# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- HemolysinCabind PF00353.19 OAG13192.1 - 2.6e-12 46.5 32.7 8.7e-09 35.2 17.7 3.3 2 1 1 3 3 3 2 RTX calcium-binding nonapeptide repeat (4 copies) DDE_3 PF13358.6 OAG13193.1 - 6.6e-09 35.7 0.0 6.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Shikimate_DH PF01488.20 OAG13194.1 - 0.076 13.1 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CcmD PF04995.14 OAG13195.1 - 0.017 15.2 1.4 0.048 13.7 1.4 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NQR2_RnfD_RnfE PF03116.15 OAG13195.1 - 0.05 13.0 0.4 0.089 12.2 0.4 1.3 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family LapA_dom PF06305.11 OAG13195.1 - 0.074 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TPX2 PF06886.11 OAG13196.1 - 0.022 15.0 0.1 0.029 14.6 0.1 1.1 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) C6_DPF PF10170.9 OAG13197.1 - 3.8 8.0 9.6 9.1 6.7 3.1 2.6 2 1 1 3 3 3 0 Cysteine-rich domain DEAD PF00270.29 OAG13198.1 - 4.6e-08 33.0 0.0 5.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG13198.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG13199.1 - 3.8e-10 40.1 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG13199.1 - 0.063 14.0 1.1 0.082 13.6 0.1 1.7 2 0 0 2 2 2 0 RecQ zinc-binding Opy2 PF09463.10 OAG13199.1 - 1.3 9.4 4.3 2.2 8.7 0.5 2.2 2 0 0 2 2 2 0 Opy2 protein Mur_ligase_M PF08245.12 OAG13200.1 - 1.5e-13 51.2 0.1 3.1e-13 50.2 0.1 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAG13200.1 - 8.9e-11 41.9 0.0 4.9e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain LptD PF04453.14 OAG13201.1 - 1.9e-17 63.6 7.8 2.8e-17 63.0 7.8 1.2 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 OAG13201.1 - 0.00029 21.0 0.1 0.00069 19.8 0.1 1.7 1 0 0 1 1 1 1 OstA-like protein Sigma70_ner PF04546.13 OAG13202.1 - 0.1 12.5 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 OAG13202.1 - 0.72 8.1 7.5 0.9 7.7 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG13202.1 - 0.74 8.0 8.0 0.94 7.6 8.0 1.3 1 0 0 1 1 1 0 Nop14-like family PC-Esterase PF13839.6 OAG13203.1 - 0.037 13.8 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RyR PF02026.16 OAG13206.1 - 3.8e-09 36.6 0.4 4.2e-05 23.7 0.2 2.6 2 0 0 2 2 2 2 RyR domain AAA_16 PF13191.6 OAG13206.1 - 0.00081 19.8 0.9 0.0046 17.4 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG13206.1 - 0.0095 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG13206.1 - 0.016 15.8 0.0 0.056 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OAG13206.1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain Torsin PF06309.11 OAG13206.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF87 PF01935.17 OAG13206.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 OAG13206.1 - 0.092 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG13206.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NLPC_P60 PF00877.19 OAG13209.1 - 4.2e-24 84.6 0.0 1e-22 80.2 0.0 3.0 3 0 0 3 3 3 1 NlpC/P60 family Peptidase_C92 PF05708.12 OAG13209.1 - 1.2e-09 38.5 0.0 0.0013 18.9 0.0 3.3 2 1 1 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Cadherin_5 PF17892.1 OAG13209.1 - 2.4e-09 37.0 0.9 1.1e-08 34.9 0.9 2.2 1 0 0 1 1 1 1 Cadherin-like domain Big_9 PF17963.1 OAG13209.1 - 1.2e-05 25.9 3.5 1.2e-05 25.9 3.5 5.9 5 1 0 5 5 5 1 Bacterial Ig domain Cadherin_4 PF17803.1 OAG13209.1 - 0.0038 17.8 9.2 0.0038 17.8 9.2 5.0 5 1 0 5 5 5 1 Bacterial cadherin-like domain Amidase_5 PF05382.13 OAG13209.1 - 0.0075 16.2 0.6 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 Bacteriophage peptidoglycan hydrolase Atg29_N PF18388.1 OAG13209.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Atg29 N-terminal domain DEAD PF00270.29 OAG13211.1 - 2.6e-08 33.8 0.0 4.5e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG13211.1 - 3.6e-06 27.3 0.0 8.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG13211.1 - 0.00039 20.5 0.0 0.017 15.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UN_NPL4 PF11543.8 OAG13212.1 - 0.013 16.0 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Endonuc-BsobI PF09194.10 OAG13213.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BsobI GUCT PF08152.12 OAG13215.1 - 0.09 13.1 0.0 0.098 13.0 0.0 1.1 1 0 0 1 1 1 0 GUCT (NUC152) domain HET PF06985.11 OAG13216.1 - 1.1e-26 93.9 0.1 1.8e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 OAG13218.1 - 4.4e-13 49.4 0.3 2.8e-06 27.8 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HET PF06985.11 OAG13218.1 - 2.9e-12 47.1 9.0 1.7e-09 38.2 3.5 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAG13218.1 - 1.8e-11 44.4 0.8 1.8e-10 41.3 0.7 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG13218.1 - 1.4e-10 41.1 3.2 0.047 14.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 OAG13218.1 - 3e-10 40.3 0.1 8.6e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 OAG13218.1 - 1.7e-05 25.0 0.6 0.11 12.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG13218.1 - 3.6e-05 23.8 0.2 0.94 10.2 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat AAA PF00004.29 OAG13218.1 - 0.00064 20.1 0.0 0.0026 18.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG13218.1 - 0.0046 17.3 0.1 0.028 14.8 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAG13218.1 - 0.019 15.0 0.1 0.16 12.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG13218.1 - 0.02 15.3 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 OAG13218.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAG13218.1 - 0.032 14.5 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rep_N PF08724.10 OAG13218.1 - 0.14 11.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Rep protein catalytic domain like DUF3435 PF11917.8 OAG13219.1 - 9.1e-138 459.7 3.0 1.6e-82 277.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) zf-met PF12874.7 OAG13219.1 - 0.22 12.0 3.4 0.39 11.2 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG13219.1 - 0.67 11.0 5.8 2.7 9.1 1.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG13219.1 - 0.96 10.0 5.8 12 6.5 0.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type HET PF06985.11 OAG13220.1 - 1e-11 45.4 14.3 3.3e-11 43.8 0.5 3.2 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG13220.1 - 1.3e-10 41.4 0.4 3.1e-10 40.2 0.4 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG13220.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG13220.1 - 0.0023 18.4 0.0 0.012 16.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf_C2H2_13 PF18508.1 OAG13220.1 - 0.006 16.2 0.3 0.013 15.0 0.3 1.6 1 0 0 1 1 1 1 Zinc finger domain RNA_helicase PF00910.22 OAG13220.1 - 0.006 17.0 0.3 0.021 15.2 0.0 2.1 2 1 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAG13220.1 - 0.013 15.5 0.1 0.13 12.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG13220.1 - 0.041 13.1 0.1 0.09 12.0 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OAG13220.1 - 0.053 13.9 0.0 0.21 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain ToxB_N PF18224.1 OAG13220.1 - 0.18 11.8 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 ToxB N-terminal domain AAA_17 PF13207.6 OAG13220.1 - 0.18 12.2 0.3 1.5 9.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain Mo-co_dimer PF03404.16 OAG13222.1 - 0.13 12.2 0.1 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain Patatin PF01734.22 OAG13223.1 - 1.8e-22 80.5 0.0 3.7e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 OAG13223.1 - 5.2e-11 42.0 5.8 1.5e-07 31.0 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG13223.1 - 2.3e-10 40.6 7.6 3.8e-05 23.9 0.2 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13223.1 - 2.9e-05 23.9 1.7 0.021 15.0 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG13223.1 - 5.1e-05 23.0 7.6 0.072 13.2 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG13223.1 - 0.00026 21.4 1.6 0.0016 18.8 1.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.28 OAG13223.1 - 0.00029 20.5 4.9 0.047 13.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG13223.1 - 0.0007 20.2 3.1 0.2 12.6 0.3 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 OAG13223.1 - 0.0039 16.9 4.1 0.046 13.4 1.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 OAG13223.1 - 0.014 16.0 2.1 0.062 14.0 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NB-ARC PF00931.22 OAG13223.1 - 0.038 13.2 0.0 0.12 11.6 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain TPR_2 PF07719.17 OAG13223.1 - 0.053 13.7 10.4 0.082 13.1 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG13223.1 - 0.063 13.7 2.6 0.62 10.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG13223.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_6 PF13174.6 OAG13223.1 - 2.1 9.1 13.7 2.2 9.1 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cupin_1 PF00190.22 OAG13225.1 - 5.5e-32 110.5 0.0 1.1e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG13225.1 - 3.8e-23 81.0 1.5 9e-12 44.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG13225.1 - 2.2e-07 30.5 0.1 0.0044 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG13225.1 - 0.0017 18.3 0.3 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 OAG13225.1 - 0.13 12.0 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Cupin SBP56 PF05694.11 OAG13226.1 - 2.6e-10 39.7 0.0 2.4e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 OAG13226.1 - 0.014 14.6 0.0 8.4 5.5 0.0 2.7 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Na_Ca_ex PF01699.24 OAG13227.1 - 1.8e-51 174.1 39.1 1.2e-28 100.0 16.4 3.2 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Acetyltransf_1 PF00583.25 OAG13229.1 - 1.9e-13 50.6 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG13229.1 - 1.5e-08 34.9 0.1 2e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG13229.1 - 1.6e-08 34.5 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG13229.1 - 0.00045 20.3 0.0 0.0005 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG13229.1 - 0.00074 19.6 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OAG13229.1 - 0.027 13.9 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 OAG13229.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Sugar_tr PF00083.24 OAG13231.1 - 6.4e-13 48.4 0.6 7.3e-13 48.2 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TPR_12 PF13424.6 OAG13232.1 - 4.8e-67 222.2 21.2 7e-20 71.1 0.7 6.0 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAG13232.1 - 1.4e-59 196.5 14.4 1e-13 50.6 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAG13232.1 - 2.4e-17 61.6 7.5 0.0032 17.4 0.0 6.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13232.1 - 1.3e-13 50.1 3.2 0.041 13.7 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG13232.1 - 1.1e-11 43.9 7.7 1.6 9.0 0.7 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.14 OAG13232.1 - 6.7e-11 41.7 0.3 0.2 12.4 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG13232.1 - 8.9e-07 28.4 0.0 0.00068 18.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_MalT PF17874.1 OAG13232.1 - 1.2e-06 28.1 4.5 0.00048 19.6 0.1 2.6 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 OAG13232.1 - 8.7e-06 26.3 6.0 0.53 11.0 0.0 5.8 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 OAG13232.1 - 0.0002 21.3 0.1 16 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG13232.1 - 0.00026 21.2 2.7 51 4.6 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_25 PF13481.6 OAG13232.1 - 0.00028 20.5 0.9 0.0013 18.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAG13232.1 - 0.00081 19.7 0.0 0.0033 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain ANAPC3 PF12895.7 OAG13232.1 - 0.0017 18.6 1.0 0.62 10.3 0.0 3.9 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG13232.1 - 0.0023 18.0 4.0 42 4.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG13232.1 - 0.0045 17.7 5.8 64 4.8 0.0 6.3 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF1925 PF09094.11 OAG13232.1 - 0.0053 17.0 0.3 22 5.4 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1925) TPR_19 PF14559.6 OAG13232.1 - 0.006 17.1 2.9 1.7 9.2 0.1 3.9 1 1 4 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OAG13232.1 - 0.014 14.9 1.2 1.4 8.3 0.1 3.3 1 1 3 4 4 4 0 Coatomer epsilon subunit AAA_16 PF13191.6 OAG13232.1 - 0.025 15.0 1.9 0.21 11.9 0.3 3.3 3 1 0 3 3 3 0 AAA ATPase domain MIT PF04212.18 OAG13232.1 - 0.083 13.0 0.0 0.93 9.6 0.0 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain AAA_24 PF13479.6 OAG13232.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rbsn PF11464.8 OAG13232.1 - 0.29 10.9 2.5 33 4.3 0.0 4.1 5 0 0 5 5 5 0 Rabenosyn Rab binding domain HET PF06985.11 OAG13233.1 - 1.7e-14 54.4 7.8 3.1e-11 43.8 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.19 OAG13234.1 - 3.2e-05 23.6 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MACPF PF01823.19 OAG13236.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 MAC/Perforin domain Peroxidase_2 PF01328.17 OAG13237.1 - 4.3e-54 183.9 0.0 5.7e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DJ-1_PfpI PF01965.24 OAG13238.1 - 3.7e-08 33.3 0.0 5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family NmrA PF05368.13 OAG13240.1 - 1.3e-14 54.3 0.1 1.6e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13240.1 - 7.6e-06 25.9 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG13240.1 - 0.00023 21.6 0.0 0.0021 18.5 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG13240.1 - 0.0047 17.2 0.0 0.03 14.6 0.0 2.2 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glyoxalase PF00903.25 OAG13241.1 - 2.9e-13 50.1 0.0 3.5e-12 46.6 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG13241.1 - 1.9e-05 24.9 0.0 3.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG13241.1 - 0.0097 16.7 0.0 0.055 14.3 0.0 2.4 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAG13241.1 - 0.029 14.3 0.0 25 4.8 0.0 3.0 3 0 0 3 3 3 0 Glyoxalase-like domain TxDE PF18711.1 OAG13241.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme FAD_binding_3 PF01494.19 OAG13242.1 - 2.6e-23 82.9 0.6 3.9e-15 56.0 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG13242.1 - 2.6e-05 24.3 0.3 6.4e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG13242.1 - 0.0013 18.3 0.6 0.0058 16.2 0.3 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG13242.1 - 0.0039 16.0 0.2 0.0055 15.5 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG13242.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG13242.1 - 0.012 14.9 0.0 0.05 12.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG13242.1 - 0.015 14.4 0.4 0.028 13.5 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG13242.1 - 0.024 13.8 0.1 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG13242.1 - 0.045 13.4 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 OAG13242.1 - 0.081 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 OAG13242.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG13242.1 - 0.2 12.2 0.2 0.54 10.9 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CDC45 PF02724.14 OAG13243.1 - 0.28 9.4 5.8 0.3 9.3 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 OAG13247.1 - 8.3e-76 255.7 19.4 9.7e-76 255.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13247.1 - 2.8e-21 75.8 27.1 9.4e-20 70.8 26.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtB PF09489.10 OAG13247.1 - 1.7 8.8 6.2 3.1 8.0 0.1 3.9 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) p450 PF00067.22 OAG13248.1 - 4.9e-62 210.2 0.0 6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MerR_1 PF13411.6 OAG13248.1 - 0.18 11.9 0.4 0.37 10.9 0.4 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein GDP_Man_Dehyd PF16363.5 OAG13249.1 - 2.9e-70 237.3 0.0 3.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG13249.1 - 1.2e-55 188.7 0.0 1.5e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG13249.1 - 2.9e-22 79.0 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG13249.1 - 3.7e-21 75.5 0.0 3.6e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG13249.1 - 2.3e-19 69.6 0.0 2.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG13249.1 - 3.3e-13 49.4 0.0 6.6e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG13249.1 - 8.6e-05 22.5 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAG13249.1 - 0.0098 15.4 0.0 1.2 8.5 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase G2BR PF18442.1 OAG13249.1 - 0.16 11.7 0.2 0.42 10.3 0.2 1.7 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) V-SNARE_C PF12352.8 OAG13250.1 - 0.2 12.0 3.7 2.1 8.7 0.5 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Glyco_hydro_38N PF01074.22 OAG13251.1 - 1.5e-86 290.4 0.1 1.5e-86 290.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAG13251.1 - 5.7e-55 186.7 0.1 6.5e-54 183.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAG13251.1 - 3.6e-28 97.5 0.0 7.6e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAG13251.1 - 8.5e-06 25.8 0.0 3.3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 OAG13251.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Hva1_TUDOR PF11160.8 OAG13253.1 - 8e-20 70.8 0.9 8e-20 70.8 0.9 2.4 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Pkinase PF00069.25 OAG13255.1 - 7.9e-61 205.7 0.0 4.3e-39 134.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13255.1 - 3.1e-27 95.5 0.0 4.4e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAG13255.1 - 1.3e-13 51.1 0.0 2.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAG13255.1 - 3.8e-07 29.7 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG13255.1 - 1.8e-05 24.8 0.0 0.001 19.0 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS PF00989.25 OAG13255.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG13255.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain Haspin_kinase PF12330.8 OAG13255.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAG13255.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 OAG13255.1 - 1.8 9.3 7.7 10 6.9 3.2 4.1 2 1 0 2 2 2 0 Protein kinase C terminal domain CFEM PF05730.11 OAG13256.1 - 3e-08 33.6 7.5 3e-08 33.6 7.5 1.9 2 0 0 2 2 2 1 CFEM domain DUF4231 PF14015.6 OAG13256.1 - 7.2 7.1 6.8 1.2 9.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF346 PF03984.13 OAG13257.1 - 7.3e-10 38.4 30.0 0.0043 16.8 0.0 7.0 7 1 0 7 7 7 5 Repeat of unknown function (DUF346) Fungal_lectin PF07938.12 OAG13257.1 - 0.019 14.3 4.9 0.15 11.5 1.4 3.2 2 1 1 3 3 3 0 Fungal fucose-specific lectin Peptidase_M6 PF05547.11 OAG13259.1 - 3.1e-06 25.9 0.2 0.0043 15.4 0.8 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Exop_C PF18559.1 OAG13259.1 - 0.024 14.5 0.5 0.59 10.0 0.5 2.3 1 1 0 1 1 1 0 Galactose-binding domain-like Abhydrolase_1 PF00561.20 OAG13260.1 - 4.8e-22 78.8 0.0 1.8e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG13260.1 - 6.6e-18 64.7 0.0 1.4e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAG13260.1 - 0.13 11.5 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Macro PF01661.21 OAG13261.1 - 2.1e-37 127.7 0.0 3.6e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Macro domain AA_permease_2 PF13520.6 OAG13263.1 - 1.9e-52 178.5 51.4 2.4e-52 178.2 51.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG13263.1 - 4.1e-24 85.0 45.1 5.5e-24 84.6 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 OAG13264.1 - 4.2e-10 39.6 5.9 4.2e-10 39.6 5.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG13264.1 - 2e-08 33.6 0.1 5.7e-08 32.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lactamase_B PF00753.27 OAG13265.1 - 2.3e-20 73.5 2.0 6.6e-20 72.0 2.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG13265.1 - 1.8e-06 27.6 0.2 2.9e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 OAG13266.1 - 3.8e-15 55.9 0.0 2.5e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG13266.1 - 0.023 14.7 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 OAG13266.1 - 0.036 13.7 0.2 0.13 11.8 0.2 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase SNF PF00209.18 OAG13267.1 - 1.1e-73 248.7 31.5 4.2e-51 174.2 16.6 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family MFS_1 PF07690.16 OAG13269.1 - 4.9e-12 45.4 35.8 7.5e-11 41.5 19.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAG13272.1 - 9.3e-11 42.0 0.3 4.6e-09 36.5 0.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAG13272.1 - 4.1e-10 39.6 0.0 1.2e-07 31.5 0.0 2.9 2 1 1 3 3 3 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG13272.1 - 1.7e-08 34.2 0.0 2.6e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG13272.1 - 1e-05 24.9 0.0 0.041 13.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG13272.1 - 0.00018 21.3 0.0 0.014 15.1 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 OAG13272.1 - 0.0063 16.2 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OAG13272.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein YjeF_N PF03853.15 OAG13272.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF829 PF05705.14 OAG13272.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 OAG13272.1 - 1.8 9.1 5.5 20 5.7 5.2 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.11 OAG13273.1 - 4.6e-15 56.2 0.1 4.6e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4201 PF13870.6 OAG13274.1 - 0.00062 19.5 11.2 0.00062 19.5 11.2 4.6 3 1 0 4 4 4 1 Domain of unknown function (DUF4201) MscS_porin PF12795.7 OAG13274.1 - 0.0014 18.2 4.2 0.0014 18.2 4.2 4.4 1 1 3 4 4 4 1 Mechanosensitive ion channel porin domain COMP PF11598.8 OAG13274.1 - 0.017 15.6 0.4 0.097 13.2 0.4 2.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Fez1 PF06818.15 OAG13274.1 - 9.7 6.6 67.2 0.021 15.3 7.3 5.1 2 1 3 5 5 5 0 Fez1 Peptidase_M28 PF04389.17 OAG13275.1 - 8.9e-35 120.2 0.0 1.7e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG13275.1 - 0.00012 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 YLP PF02757.17 OAG13276.1 - 0.095 12.7 3.1 0.54 10.4 0.8 2.8 2 0 0 2 2 2 0 YLP motif Bac_export_2 PF01312.19 OAG13277.1 - 0.27 10.4 11.1 0.0081 15.4 4.1 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2593 PF10767.9 OAG13277.1 - 0.69 10.0 6.7 2 8.4 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) Fungus-induced PF10917.8 OAG13280.1 - 0.25 11.7 0.1 0.8 10.1 0.0 1.9 2 0 0 2 2 2 0 Fungus-induced protein Serum_albumin PF00273.20 OAG13281.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Serum albumin family ADH_zinc_N PF00107.26 OAG13287.1 - 1.6e-09 37.8 0.2 4.3e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG13287.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG13287.1 - 0.0019 17.6 2.0 0.0032 16.8 2.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 OAG13287.1 - 0.13 12.2 0.4 1.9 8.4 0.1 2.4 3 0 0 3 3 3 0 NAD(P)H-binding CFEM PF05730.11 OAG13288.1 - 0.0018 18.3 5.8 0.0028 17.7 5.8 1.4 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 OAG13289.1 - 3e-79 266.9 0.0 3.9e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAG13289.1 - 1.1e-33 116.7 0.0 1.8e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG13289.1 - 8e-24 84.5 0.1 2.1e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG13289.1 - 4.7e-13 49.7 0.0 2.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG13289.1 - 0.0052 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain FA_desaturase PF00487.24 OAG13291.1 - 3.5e-26 92.6 19.8 5.1e-26 92.0 19.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG13291.1 - 7.6e-06 26.2 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Glyco_hydro_3_C PF01915.22 OAG13292.1 - 1.4e-43 149.2 0.0 2.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG13292.1 - 3.5e-34 118.6 0.0 6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG13292.1 - 2.4e-22 78.8 0.0 4.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NPR3 PF03666.13 OAG13295.1 - 6.7e-137 457.1 0.0 1.3e-136 456.1 0.0 1.5 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Cyclin PF08613.11 OAG13296.1 - 0.032 14.6 0.0 0.058 13.8 0.0 1.4 1 1 0 1 1 1 0 Cyclin CorA PF01544.18 OAG13297.1 - 4.5e-31 108.2 9.4 1.8e-22 80.0 1.8 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Mito_fiss_reg PF05308.11 OAG13297.1 - 0.0001 22.5 0.3 0.0001 22.5 0.3 2.0 2 0 0 2 2 2 1 Mitochondrial fission regulator Brr6_like_C_C PF10104.9 OAG13297.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Methyltransf_2 PF00891.18 OAG13299.1 - 2.2e-18 66.3 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain APH PF01636.23 OAG13301.1 - 1.7e-16 60.9 0.0 4.9e-16 59.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Transferase PF02458.15 OAG13302.1 - 1.7e-28 99.5 0.0 2.8e-28 98.8 0.0 1.3 1 1 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.26 OAG13303.1 - 1.4e-69 234.5 0.3 3.8e-69 233.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG13303.1 - 7.8e-57 193.2 0.1 1.2e-56 192.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG13303.1 - 7.3e-35 120.6 0.0 1.2e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG13303.1 - 6.8e-33 113.2 1.0 1.8e-32 111.8 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 OAG13303.1 - 1.1e-27 97.2 3.1 3.8e-25 88.9 0.0 3.3 2 1 1 3 3 3 1 KR domain KAsynt_C_assoc PF16197.5 OAG13303.1 - 1.9e-12 47.6 0.0 4.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OAG13303.1 - 3.6e-09 36.9 0.2 9.2e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 OAG13303.1 - 4.2e-09 37.1 0.0 1.5e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG13303.1 - 6.1e-07 30.0 0.0 2.4e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG13303.1 - 2.3e-06 27.5 0.0 8.6e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG13303.1 - 1e-05 25.4 0.0 3.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG13303.1 - 1.2e-05 25.9 0.0 9.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 OAG13303.1 - 0.00011 21.7 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 OAG13303.1 - 0.0021 18.0 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG13303.1 - 0.0063 16.0 0.0 0.021 14.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase ACP_syn_III PF08545.10 OAG13303.1 - 0.08 12.8 0.1 0.27 11.1 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 OAG13303.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1770 PF08589.10 OAG13303.1 - 0.15 13.0 0.0 0.43 11.6 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) PMT_4TMC PF16192.5 OAG13306.1 - 0.0039 16.8 1.0 0.01 15.4 0.1 1.8 1 1 1 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase DUF5336 PF17270.2 OAG13306.1 - 1.4 8.5 8.5 4.8 6.8 8.6 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5336) Peptidase_C14 PF00656.22 OAG13307.1 - 1.1e-07 32.0 0.0 3.3e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DUF1889 PF08986.10 OAG13307.1 - 0.005 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1889) Raptor_N PF14538.6 OAG13307.1 - 0.078 12.9 0.7 0.44 10.5 0.5 2.4 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain MFS_1 PF07690.16 OAG13308.1 - 5.6e-17 61.7 64.9 1e-12 47.7 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 OAG13310.1 - 2.2e-11 44.3 9.5 5.2e-10 39.8 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 OAG13312.1 - 0.12 13.0 0.2 15 6.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat FCH PF00611.23 OAG13312.1 - 0.23 11.8 0.3 5.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DNA_methylase PF00145.17 OAG13313.1 - 5.1e-24 85.2 0.0 1.2e-22 80.7 0.0 2.6 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 OAG13313.1 - 2.1e-06 27.6 0.1 0.086 12.7 0.0 3.2 2 1 0 2 2 2 2 BAH domain Amidohydro_2 PF04909.14 OAG13314.1 - 2.8e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 OAG13314.1 - 0.0036 16.7 0.0 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Ank_2 PF12796.7 OAG13315.1 - 1.3e-10 41.7 3.8 9e-08 32.6 0.4 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG13315.1 - 2.9e-09 37.3 2.4 0.00035 21.1 0.5 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG13315.1 - 1.1e-06 28.5 1.5 0.21 12.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAG13315.1 - 1.4e-05 25.3 6.3 0.01 16.3 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG13315.1 - 0.00018 21.7 3.8 0.0013 19.0 1.5 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG13316.1 - 1.8e-23 82.9 2.6 5e-09 36.6 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG13316.1 - 1.3e-19 68.2 4.2 1.9e-05 24.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OAG13316.1 - 3.5e-19 68.9 3.2 9e-08 32.5 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG13316.1 - 2.1e-18 65.8 9.6 1.1e-05 25.7 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OAG13316.1 - 1.7e-17 63.2 9.5 1.1e-08 35.1 0.3 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) RecQ5 PF06959.11 OAG13316.1 - 0.092 12.7 0.0 4.3 7.3 0.0 2.1 1 1 1 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) BCMA-Tall_bind PF09257.10 OAG13316.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 BCMA, TALL-1 binding DUF676 PF05057.14 OAG13317.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Importin_rep_5 PF18816.1 OAG13317.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Importin repeat Peptidase_S8 PF00082.22 OAG13319.1 - 3.2e-13 49.6 0.4 1e-12 48.0 0.1 2.0 2 0 0 2 2 2 1 Subtilase family Ank_2 PF12796.7 OAG13319.1 - 7.9e-08 32.8 5.0 0.003 18.1 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG13319.1 - 0.00077 20.0 0.3 0.77 10.4 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG13319.1 - 0.013 16.0 0.0 0.34 11.4 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OAG13319.1 - 0.013 16.0 2.2 1.6 9.5 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat Macin PF14865.6 OAG13319.1 - 0.14 12.7 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Macin HET PF06985.11 OAG13320.1 - 1.3e-26 93.7 0.0 2.8e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DENN PF02141.21 OAG13321.1 - 0.00079 19.4 0.8 0.0048 16.9 0.8 2.1 1 1 0 1 1 1 1 DENN (AEX-3) domain Vac14_Fig4_bd PF11916.8 OAG13322.1 - 6.2e-72 241.0 13.5 1.3e-57 194.3 4.0 2.9 3 0 0 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAG13322.1 - 1.1e-44 151.0 0.0 7.5e-42 141.9 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG13322.1 - 1.2e-09 38.5 3.1 0.019 15.4 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 OAG13322.1 - 6.4e-08 32.2 3.5 0.0036 17.4 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OAG13322.1 - 2.8e-06 27.4 1.8 0.11 12.5 0.2 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG13322.1 - 0.00012 22.3 0.8 1.5 9.2 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 OAG13322.1 - 0.05 13.7 0.0 44 4.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Vma12 PF11712.8 OAG13323.1 - 2.5e-44 150.7 0.0 4.7e-44 149.8 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TMEM171 PF15471.6 OAG13323.1 - 1 8.3 4.1 1.5 7.8 3.0 1.6 1 1 0 1 1 1 0 Transmembrane protein family 171 polyprenyl_synt PF00348.17 OAG13324.1 - 1.7e-72 243.5 0.0 2.9e-72 242.8 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase His_biosynth PF00977.21 OAG13325.1 - 2e-46 158.3 0.4 7.8e-46 156.4 0.4 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OAG13325.1 - 5.3e-23 81.8 0.0 8.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAG13325.1 - 8.6e-11 42.0 0.0 2e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG13325.1 - 3.4e-08 33.3 0.0 2.1e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OAG13325.1 - 0.0035 17.1 0.0 0.69 9.6 0.0 2.8 3 0 0 3 3 3 1 Peptidase C26 NMO PF03060.15 OAG13325.1 - 0.023 14.1 0.7 1.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Peptidase_S51 PF03575.17 OAG13325.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Ribosomal_S4 PF00163.19 OAG13326.1 - 6.1e-12 46.3 0.1 9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 OAG13326.1 - 1.3e-09 37.6 0.1 2.3e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 S4 domain TRI12 PF06609.13 OAG13327.1 - 1.4e-60 205.4 20.2 1.7e-60 205.1 20.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG13327.1 - 2e-21 76.3 43.4 1.3e-20 73.7 41.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG13327.1 - 2.5e-14 53.0 3.4 2.5e-14 53.0 3.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Sugar_tr PF00083.24 OAG13328.1 - 1.4e-95 320.9 22.1 1.6e-95 320.6 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13328.1 - 1.1e-23 83.8 47.9 3.1e-21 75.7 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IU_nuc_hydro PF01156.19 OAG13329.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cupin_5 PF06172.11 OAG13330.1 - 3.7e-40 137.4 0.1 3.7e-40 137.4 0.1 1.3 2 0 0 2 2 2 1 Cupin superfamily (DUF985) Cu-oxidase_3 PF07732.15 OAG13331.1 - 6.9e-42 142.2 6.1 7.1e-39 132.5 1.5 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG13331.1 - 5.1e-41 139.6 8.0 2.4e-35 121.3 0.5 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OAG13331.1 - 2.1e-36 125.4 1.4 3.2e-36 124.9 0.5 1.9 2 0 0 2 2 2 1 Multicopper oxidase PAP_RNA-bind PF04926.15 OAG13331.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Gpr1_Fun34_YaaH PF01184.19 OAG13332.1 - 3.7e-30 105.1 21.6 4.5e-30 104.8 21.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TMEM174 PF15029.6 OAG13332.1 - 0.48 10.1 2.8 0.19 11.4 0.3 1.7 2 0 0 2 2 2 0 Transmembrane protein 174 Cir_N PF10197.9 OAG13333.1 - 2.8e-05 24.2 0.3 2.8e-05 24.2 0.3 4.5 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PRP1_N PF06424.12 OAG13335.1 - 3.6e-51 173.4 8.4 1.2e-50 171.7 8.4 2.0 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 OAG13335.1 - 1.7e-28 98.9 0.4 7.2e-05 23.2 0.0 10.7 7 1 3 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAG13335.1 - 9.8e-28 94.5 12.6 0.0004 21.0 0.0 14.5 5 4 9 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAG13335.1 - 1.3e-09 37.5 2.7 13 6.2 0.0 11.0 14 0 0 14 14 13 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG13335.1 - 2e-08 34.8 6.0 0.069 13.8 0.0 7.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13335.1 - 1.8e-05 24.3 0.6 7.1 6.6 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13335.1 - 2.6e-05 24.1 0.4 6 7.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG13335.1 - 0.00016 21.3 2.0 4.8 7.0 0.0 5.9 7 0 0 7 7 7 1 TPR repeat TPR_4 PF07721.14 OAG13335.1 - 0.00029 21.2 0.2 8.4 7.3 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG13335.1 - 0.00042 19.6 15.3 0.1 11.7 0.1 5.4 4 2 2 6 6 6 3 NRDE-2, necessary for RNA interference ANAPC3 PF12895.7 OAG13335.1 - 0.0007 19.8 0.0 2.7 8.3 0.0 4.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAG13335.1 - 0.0012 18.9 0.6 0.73 10.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG13335.1 - 0.002 18.4 8.0 1.6 9.1 0.1 7.6 6 2 2 8 8 7 1 Tetratricopeptide repeat ChAPs PF09295.10 OAG13335.1 - 0.0048 15.9 2.7 0.073 12.1 0.0 3.3 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 OAG13335.1 - 0.0067 16.4 0.4 47 4.3 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat YfiO PF13525.6 OAG13335.1 - 0.016 14.9 0.1 0.14 11.8 0.0 2.7 3 0 0 3 3 2 0 Outer membrane lipoprotein SNAP PF14938.6 OAG13335.1 - 0.017 14.6 2.2 0.19 11.1 0.3 3.6 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP DUF3808 PF10300.9 OAG13335.1 - 0.036 12.8 0.1 5 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_17 PF13431.6 OAG13335.1 - 0.056 13.8 4.8 3.9e+02 1.8 0.0 7.8 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG13335.1 - 0.13 13.0 10.7 1.2e+02 3.6 0.1 8.0 9 1 1 10 10 7 0 Tetratricopeptide repeat TUSC2 PF15000.6 OAG13335.1 - 0.67 10.3 3.3 1.7 9.0 3.3 1.7 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Fungal_trans PF04082.18 OAG13336.1 - 1.2e-19 70.3 1.0 1.6e-19 70.0 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13336.1 - 0.00019 21.5 13.7 0.00048 20.2 13.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 OAG13337.1 - 4e-08 32.7 0.3 6e-08 32.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 OAG13338.1 - 2.5e-21 76.0 20.7 2.5e-21 76.0 20.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 OAG13338.1 - 0.042 13.7 1.7 0.67 9.8 0.1 2.4 2 0 0 2 2 2 0 VIT family DUF2070 PF09843.9 OAG13338.1 - 5.5 5.2 7.5 8.1 4.6 7.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2264 PF10022.9 OAG13339.1 - 8.9e-130 432.9 1.2 1.1e-129 432.6 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) NmrA PF05368.13 OAG13340.1 - 1.7e-16 60.5 0.1 2.7e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13340.1 - 3.1e-10 40.2 0.0 5.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG13340.1 - 0.0005 20.0 0.1 0.001 19.0 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG13340.1 - 0.0022 17.5 0.6 0.0075 15.8 0.3 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG13340.1 - 0.029 14.7 0.1 0.05 13.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG13340.1 - 0.075 13.1 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG13340.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2235 PF09994.9 OAG13341.1 - 2.3e-69 233.9 0.1 1.7e-54 185.1 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) NYD-SP28 PF14772.6 OAG13341.1 - 0.069 13.2 1.2 0.13 12.4 1.2 1.3 1 0 0 1 1 1 0 Sperm tail ATG_C PF09333.11 OAG13343.1 - 0.037 14.4 0.1 0.052 13.9 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Herpes_capsid PF06112.11 OAG13344.1 - 2.1 8.4 12.2 4.1 7.5 12.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3433 PF11915.8 OAG13345.1 - 6.8e-13 48.9 1.4 2e-12 47.4 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) ADP_ribosyl_GH PF03747.14 OAG13347.1 - 3.1e-59 201.1 3.9 3.5e-59 200.9 3.9 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NapD PF03927.13 OAG13348.1 - 0.077 13.1 0.2 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 NapD protein NmrA PF05368.13 OAG13350.1 - 2.8e-08 33.6 0.0 3.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13350.1 - 0.00028 20.8 0.0 0.00055 19.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF2673 PF10880.8 OAG13350.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) SnoaL_4 PF13577.6 OAG13351.1 - 3.6e-07 30.4 0.0 5.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG13351.1 - 0.0013 19.3 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Dioxygenase_N PF04444.14 OAG13351.1 - 0.028 14.3 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Polyketide_cyc2 PF10604.9 OAG13352.1 - 0.0005 20.3 0.1 0.00086 19.6 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3752 PF12572.8 OAG13353.1 - 5.4e-50 169.9 12.6 1.1e-49 168.9 12.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 OAG13353.1 - 0.0059 16.0 1.9 0.0075 15.6 1.9 1.1 1 0 0 1 1 1 1 Dynamitin Vps8 PF12816.7 OAG13354.1 - 3.8e-69 232.2 0.2 8.2e-69 231.1 0.2 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAG13354.1 - 6.6e-08 32.5 0.3 0.00017 21.5 0.5 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 OAG13354.1 - 0.14 12.2 0.5 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 OAG13354.1 - 1.7 8.5 4.0 0.5 10.2 0.0 2.3 3 0 0 3 3 3 0 RING-like zinc finger Amidase PF01425.21 OAG13357.1 - 8.5e-92 308.5 0.0 4e-91 306.3 0.0 1.8 1 1 0 1 1 1 1 Amidase Zn_clus PF00172.18 OAG13358.1 - 0.14 12.3 10.5 0.28 11.4 10.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 OAG13359.1 - 2.4e-10 40.3 4.6 0.01 15.9 0.0 5.3 5 0 0 5 5 5 3 LysM domain HTH_Tnp_IS630 PF01710.16 OAG13359.1 - 0.15 12.1 0.0 0.64 10.1 0.0 2.0 3 0 0 3 3 3 0 Transposase zf-RRN7 PF11781.8 OAG13359.1 - 9.3 6.0 8.9 5.9 6.7 0.1 3.6 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Retrotran_gag_3 PF14244.6 OAG13360.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Glyco_hydro_18 PF00704.28 OAG13361.1 - 1e-53 183.1 4.8 1e-53 183.1 3.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 OAG13361.1 - 1e-08 35.1 0.0 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 OAG13361.1 - 3e-05 24.4 7.8 3e-05 24.4 7.8 3.2 3 0 0 3 3 3 1 Chitin recognition protein 2OG-FeII_Oxy_3 PF13640.6 OAG13362.1 - 5e-08 33.7 0.0 7.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.23 OAG13364.1 - 1.3e-21 76.8 0.1 2.6e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13364.1 - 0.0031 17.6 0.2 0.0062 16.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4336 PF14234.6 OAG13366.1 - 2.1e-08 33.8 0.0 0.00037 19.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Pkinase PF00069.25 OAG13367.1 - 2.7e-17 63.0 0.0 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13367.1 - 2.7e-09 36.7 0.0 5.4e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Transcrip_act PF04949.13 OAG13367.1 - 0.1 12.5 0.8 0.25 11.2 0.8 1.6 1 0 0 1 1 1 0 Transcriptional activator Propeptide_C25 PF08126.11 OAG13367.1 - 0.17 10.9 0.1 0.31 10.1 0.1 1.3 1 0 0 1 1 1 0 Propeptide_C25 HET PF06985.11 OAG13368.1 - 2.2e-24 86.4 0.1 5.8e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG13368.1 - 4.8e-23 81.9 0.0 9.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13368.1 - 1.1e-15 57.7 0.0 2.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3930 PF13067.6 OAG13369.1 - 0.011 16.0 0.1 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) DUF202 PF02656.15 OAG13369.1 - 0.28 11.7 7.7 1.4 9.4 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2070 PF09843.9 OAG13369.1 - 0.41 8.9 4.1 0.51 8.6 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BTAD PF03704.17 OAG13371.1 - 0.011 16.1 0.1 2 8.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Glyco_transf_28 PF03033.20 OAG13372.1 - 1.8e-22 79.9 0.0 3.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain VPS13_C PF16909.5 OAG13372.1 - 3.5e-05 23.7 1.1 6.5e-05 22.8 1.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OAG13372.1 - 0.00011 22.5 0.1 0.00088 19.6 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 OAG13372.1 - 0.00011 21.2 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG13372.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_10 PF00331.20 OAG13373.1 - 1.8e-70 237.6 0.0 2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PIH1 PF08190.12 OAG13373.1 - 0.076 12.5 0.0 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 PIH1 N-terminal domain RNase_H PF00075.24 OAG13374.1 - 7.4e-08 32.7 0.1 8e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 RNase H PUL PF08324.11 OAG13375.1 - 2.3e-46 158.3 0.0 3.2e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 OAG13375.1 - 1.2e-35 122.6 0.0 2e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 OAG13375.1 - 9.5e-09 35.2 0.0 2.5e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG13375.1 - 0.0046 17.4 0.4 0.058 13.9 0.4 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAG13375.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein WAPL PF07814.13 OAG13375.1 - 0.063 12.1 0.0 0.16 10.7 0.0 1.5 1 1 1 2 2 2 0 Wings apart-like protein regulation of heterochromatin Cnd1 PF12717.7 OAG13375.1 - 0.085 12.9 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF4690 PF15756.5 OAG13377.1 - 0.0056 17.2 0.2 0.0087 16.6 0.2 1.3 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 OAG13377.1 - 0.011 16.0 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A DAG1 PF05454.11 OAG13377.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.4 1 1 1 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 OAG13377.1 - 0.12 13.2 0.0 0.14 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.13 OAG13377.1 - 0.17 12.1 0.0 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA TMEM52 PF14979.6 OAG13377.1 - 6.6 6.6 8.7 3.3 7.6 1.6 2.6 1 1 1 3 3 3 0 Transmembrane 52 GMC_oxred_N PF00732.19 OAG13378.1 - 1.4e-66 224.8 0.0 1.9e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG13378.1 - 1.3e-31 110.1 0.1 2.7e-31 109.0 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG13378.1 - 0.00012 22.3 0.9 0.00048 20.3 0.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG13378.1 - 0.00092 18.5 0.1 0.0016 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAG13378.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG13378.1 - 0.0039 16.5 0.1 0.0077 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG13378.1 - 0.0067 15.6 0.2 0.13 11.3 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG13378.1 - 0.019 14.6 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG13378.1 - 0.051 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG13378.1 - 0.12 11.1 0.2 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG13378.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG13378.1 - 0.17 12.1 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_34 PF11312.8 OAG13379.1 - 1.7e-112 375.6 0.1 2e-112 375.4 0.1 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_31 PF13847.6 OAG13379.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMD PF02627.20 OAG13380.1 - 5.3e-10 39.2 0.1 7.7e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.19 OAG13380.1 - 0.087 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PTPLA PF04387.14 OAG13381.1 - 8.2e-55 185.0 8.8 1.1e-54 184.6 8.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA zf-RING_5 PF14634.6 OAG13382.1 - 0.00077 19.4 3.6 0.0014 18.6 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG13382.1 - 0.01 15.9 1.5 0.02 14.9 1.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAG13382.1 - 0.031 14.6 2.4 0.066 13.6 2.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAG13382.1 - 0.13 12.1 2.9 0.31 10.9 2.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG13382.1 - 0.14 12.1 3.4 0.34 10.8 3.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG13382.1 - 0.31 10.9 2.0 0.7 9.8 2.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG13382.1 - 0.53 10.2 5.3 3.9 7.4 5.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG13382.1 - 0.62 10.3 3.0 0.87 9.8 0.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prp19 PF08606.11 OAG13383.1 - 2.7e-34 117.0 1.9 5e-34 116.1 1.9 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 OAG13383.1 - 1.4e-18 66.9 0.9 5.2e-05 23.5 0.0 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG13383.1 - 8.3e-14 51.8 6.4 0.00098 19.9 0.0 5.9 6 0 0 6 6 5 3 WD domain, G-beta repeat WD40_like PF17005.5 OAG13383.1 - 8.6e-08 31.8 0.0 0.011 15.0 0.0 2.6 1 1 2 3 3 3 2 WD40-like domain eIF2A PF08662.11 OAG13383.1 - 2e-07 31.1 0.7 3.1e-06 27.2 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OAG13383.1 - 3.7e-05 23.0 1.0 0.00016 20.9 0.4 2.3 1 1 1 2 2 2 1 Coatomer WD associated region Mcl1_mid PF12341.8 OAG13383.1 - 0.0003 20.3 1.9 0.0023 17.4 0.2 2.2 1 1 1 2 2 2 2 Minichromosome loss protein, Mcl1, middle region U-box PF04564.15 OAG13383.1 - 0.00036 20.7 0.1 0.00085 19.5 0.0 1.6 2 0 0 2 2 1 1 U-box domain HPS3_N PF14761.6 OAG13383.1 - 0.00046 19.8 0.0 0.031 13.8 0.0 2.3 1 1 1 2 2 2 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 OAG13383.1 - 0.00093 17.6 0.2 0.036 12.4 0.0 1.9 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 OAG13383.1 - 0.0011 18.8 0.7 0.12 12.4 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 OAG13383.1 - 0.015 13.8 0.1 0.08 11.5 0.0 2.0 1 1 0 2 2 2 0 Cytochrome D1 heme domain zf-Nse PF11789.8 OAG13383.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3450 PF11932.8 OAG13383.1 - 0.026 13.8 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PQQ_3 PF13570.6 OAG13383.1 - 0.027 15.0 2.7 12 6.6 0.5 3.5 3 0 0 3 3 3 0 PQQ-like domain Lactonase PF10282.9 OAG13383.1 - 0.032 13.5 0.9 0.69 9.1 0.0 2.6 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller V_ATPase_I_N PF18670.1 OAG13383.1 - 0.048 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Ge1_WD40 PF16529.5 OAG13383.1 - 0.28 10.1 1.0 1.7 7.5 0.1 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_31 PF01055.26 OAG13384.1 - 2.9e-156 521.1 4.3 3.7e-156 520.7 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG13384.1 - 1.7e-37 128.2 0.0 3.4e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG13384.1 - 2.6e-13 50.1 0.7 6.9e-13 48.7 0.7 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like SRP9-21 PF05486.12 OAG13386.1 - 1.4e-30 105.5 0.4 1.9e-30 105.1 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) GPS2_interact PF15784.5 OAG13386.1 - 0.047 14.1 0.9 0.13 12.7 1.1 1.6 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF1308 PF07000.11 OAG13387.1 - 8.2e-06 25.8 0.0 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Herpes_UL52 PF03121.15 OAG13388.1 - 0.77 9.7 2.4 13 5.8 0.5 2.3 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase WSC PF01822.19 OAG13389.1 - 3.1e-17 62.5 6.7 8.4e-17 61.1 6.7 1.7 1 0 0 1 1 1 1 WSC domain Peroxidase_2 PF01328.17 OAG13390.1 - 1.5e-52 178.8 0.2 1.9e-52 178.5 0.2 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DIX PF00778.17 OAG13390.1 - 0.049 13.5 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 DIX domain Beta_helix PF13229.6 OAG13391.1 - 2e-10 40.8 12.3 1.1e-09 38.4 8.4 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 OAG13391.1 - 4.5e-08 32.4 0.0 9e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 OAG13391.1 - 0.014 14.7 0.4 0.014 14.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) APC_N_CC PF16689.5 OAG13392.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain GFO_IDH_MocA PF01408.22 OAG13393.1 - 2.2e-18 67.2 0.0 4.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG13393.1 - 4.6e-09 36.3 0.1 7.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG13393.1 - 0.11 13.1 0.1 0.19 12.4 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 OAG13394.1 - 5.3e-06 25.5 0.6 7.8e-06 24.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 OAG13395.1 - 1.4e-48 165.6 0.0 8.7e-42 143.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Arc_PepC PF06819.11 OAG13395.1 - 0.099 12.8 0.2 0.31 11.2 0.1 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain SBP_bac_8 PF13416.6 OAG13395.1 - 0.14 12.0 0.3 0.55 10.0 0.1 1.8 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Sugar_tr PF00083.24 OAG13396.1 - 3.1e-103 346.1 25.2 3.6e-103 345.8 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13396.1 - 5.9e-21 74.8 28.7 5.9e-21 74.8 28.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG13396.1 - 2.7e-07 29.4 3.0 2.7e-07 29.4 3.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 OAG13396.1 - 0.00092 19.0 1.3 0.00092 19.0 1.3 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Phage_holin_2_1 PF04971.12 OAG13396.1 - 4.5 7.4 9.1 0.48 10.5 1.4 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S FMO-like PF00743.19 OAG13397.1 - 1.1e-21 76.9 0.0 2.2e-15 56.1 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG13397.1 - 3.8e-21 75.6 0.0 1e-19 70.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG13397.1 - 2.3e-10 40.2 0.0 5.7e-08 32.3 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG13397.1 - 8.7e-09 35.0 0.1 7.4e-07 28.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG13397.1 - 9e-08 32.6 0.3 0.0078 16.8 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13397.1 - 1.9e-07 31.2 0.0 0.00013 22.2 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG13397.1 - 0.00014 21.2 0.0 0.0019 17.5 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 OAG13397.1 - 0.00034 20.1 0.0 0.9 8.8 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.24 OAG13397.1 - 0.00047 19.8 0.3 0.039 13.5 0.1 3.2 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG13397.1 - 0.002 18.2 0.7 2 8.4 0.4 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG13397.1 - 0.0032 16.6 0.2 0.012 14.6 0.1 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAG13397.1 - 0.0056 16.1 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG13397.1 - 0.0068 15.2 0.0 0.077 11.7 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG13397.1 - 0.031 13.3 0.2 0.069 12.2 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG13397.1 - 0.1 11.8 0.0 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAG13397.1 - 0.11 11.5 0.0 2.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 OAG13397.1 - 0.2 11.9 0.0 0.62 10.3 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain DUF1962 PF09227.10 OAG13398.1 - 0.13 12.6 6.9 0.3 11.5 7.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1962) Fer4_22 PF17179.4 OAG13399.1 - 0.69 10.8 3.2 0.88 10.5 0.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain NmrA PF05368.13 OAG13400.1 - 3.3e-38 131.5 0.0 4.1e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13400.1 - 4.3e-15 56.1 0.0 5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13400.1 - 1.9e-05 24.2 0.0 5.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG13400.1 - 0.00017 20.8 0.0 0.00036 19.8 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG13400.1 - 0.00059 19.1 0.0 0.00098 18.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 OAG13400.1 - 0.0026 17.7 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG13400.1 - 0.0054 15.8 0.0 0.009 15.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG13400.1 - 0.023 14.2 0.2 0.047 13.1 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 OAG13400.1 - 0.029 14.5 0.1 0.055 13.6 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 OAG13400.1 - 0.066 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UPRTase PF14681.6 OAG13400.1 - 0.079 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Semialdhyde_dh PF01118.24 OAG13400.1 - 0.15 12.5 0.1 0.39 11.2 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OAG13401.1 - 0.00046 20.2 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 OAG13401.1 - 0.027 15.3 0.0 0.05 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 OAG13402.1 - 1.2e-21 77.8 0.1 4.2e-21 76.0 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold BNR_2 PF13088.6 OAG13403.1 - 7.3e-49 166.5 0.2 1.3e-48 165.7 0.2 1.3 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OAG13403.1 - 5.4e-05 22.6 9.5 0.81 9.9 0.0 4.5 3 0 0 3 3 3 3 BNR/Asp-box repeat Sugar_tr PF00083.24 OAG13404.1 - 2.5e-92 310.1 28.2 2.8e-92 309.9 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13404.1 - 3.4e-22 78.9 45.3 4.4e-21 75.2 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAG13405.1 - 7.4e-20 71.5 0.1 5.5e-08 32.6 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13405.1 - 2.5e-14 53.2 0.0 2.5e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase APG5 PF04106.12 OAG13405.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Sugar_tr PF00083.24 OAG13406.1 - 2.6e-85 287.0 22.2 3.1e-85 286.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13406.1 - 4.4e-23 81.8 39.3 2.1e-16 59.8 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG13406.1 - 0.005 15.3 2.8 0.0093 14.4 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-RNPHF PF08080.12 OAG13406.1 - 1.7 8.7 4.1 1.1e+02 2.9 0.2 3.4 3 0 0 3 3 3 0 RNPHF zinc finger Gly-zipper_Omp PF13488.6 OAG13406.1 - 3 7.9 8.0 0.18 11.8 2.1 2.1 2 0 0 2 2 2 0 Glycine zipper Polyketide_cyc2 PF10604.9 OAG13407.1 - 0.034 14.4 0.2 0.074 13.3 0.2 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport LVIVD PF08309.11 OAG13407.1 - 0.053 12.8 0.1 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 LVIVD repeat Polyketide_cyc PF03364.20 OAG13407.1 - 0.1 12.8 0.4 0.2 11.9 0.4 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Aa_trans PF01490.18 OAG13408.1 - 6.4e-36 123.9 30.0 7.4e-36 123.7 30.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 OAG13408.1 - 0.00017 20.5 26.2 0.039 12.8 17.0 3.9 2 2 1 3 3 3 3 Spore germination protein AA_permease_2 PF13520.6 OAG13408.1 - 0.00034 19.6 38.9 0.04 12.8 38.9 2.1 1 1 0 1 1 1 1 Amino acid permease DUF2534 PF10749.9 OAG13408.1 - 6.6 7.0 8.4 0.8 9.9 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) DHDPS PF00701.22 OAG13409.1 - 2.8e-59 200.2 0.0 3.2e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.18 OAG13410.1 - 6.1e-122 407.0 0.0 7e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG13410.1 - 1.5e-07 30.8 0.7 5e-06 25.8 0.2 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG13410.1 - 1.7e-05 24.2 0.1 3.3e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG13410.1 - 0.00022 20.8 0.1 0.46 9.9 0.0 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein Fungal_trans_2 PF11951.8 OAG13411.1 - 6.6e-37 127.2 2.7 1.1e-36 126.5 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S8 PF00082.22 OAG13412.1 - 2.9e-39 135.1 0.0 6.4e-39 134.0 0.0 1.5 1 1 1 2 2 2 1 Subtilase family fn3_5 PF06280.12 OAG13412.1 - 2.5e-17 63.6 2.3 3.9e-17 63.0 0.9 2.1 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 OAG13412.1 - 2.5e-05 24.2 0.0 8.5e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 OAG13412.1 - 0.00038 20.3 0.1 0.002 18.0 0.1 2.3 1 0 0 1 1 1 1 FlgD Ig-like domain Zn_clus PF00172.18 OAG13414.1 - 6e-07 29.5 10.4 9.9e-07 28.8 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEC-1_N PF04625.13 OAG13414.1 - 0.38 9.7 4.9 0.54 9.2 4.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Fungal_trans PF04082.18 OAG13415.1 - 0.1 11.6 0.4 1.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Fungal specific transcription factor domain CENP-B_dimeris PF09026.10 OAG13417.1 - 1.7 9.1 12.7 1.7 9.1 12.7 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain p450 PF00067.22 OAG13418.1 - 1.9e-73 247.8 0.0 2.5e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 OAG13420.1 - 1.5e-13 50.8 0.1 2.6e-13 50.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG13420.1 - 4.7e-11 42.9 0.4 1.1e-10 41.7 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG13420.1 - 3.5e-08 33.3 0.4 6.1e-08 32.5 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG13420.1 - 8.9e-08 32.5 0.2 1.7e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG13420.1 - 1e-07 31.3 0.1 2.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG13420.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 OAG13420.1 - 0.0023 18.2 0.1 0.0054 17.0 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 OAG13420.1 - 0.009 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG13420.1 - 0.013 15.5 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 OAG13420.1 - 0.036 14.2 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Abhydrolase_1 PF00561.20 OAG13421.1 - 0.036 13.7 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 OAG13422.1 - 9e-51 173.0 0.0 1.3e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG13422.1 - 1.5e-36 126.0 0.0 2.8e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG13422.1 - 2.4e-05 23.6 5.3 0.022 13.9 3.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG13422.1 - 0.0017 18.0 5.7 0.049 13.2 4.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG13422.1 - 0.0037 16.5 0.8 0.0074 15.6 0.8 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG13422.1 - 0.12 11.6 4.2 1 8.6 4.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG13422.1 - 0.14 11.2 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG13422.1 - 0.36 11.1 5.1 0.92 9.8 5.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG13422.1 - 0.61 9.1 2.2 0.56 9.2 1.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A GGACT PF06094.12 OAG13425.1 - 1.3e-15 58.0 0.0 1.8e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like adh_short PF00106.25 OAG13426.1 - 9.7e-25 87.2 0.1 1.8e-24 86.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13426.1 - 3.8e-19 69.2 0.1 6.8e-19 68.3 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2267 PF10025.9 OAG13426.1 - 0.11 12.8 0.2 0.85 9.9 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Elong_Iki1 PF10483.9 OAG13427.1 - 1.1e-79 268.0 0.0 1.3e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 OAG13428.1 - 3.9e-26 90.9 0.9 4.6e-26 90.6 0.9 1.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins FAM193_C PF15914.5 OAG13428.1 - 0.085 12.6 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 FAM193 family C-terminal Glyco_hydro_63 PF03200.16 OAG13429.1 - 5.3e-172 573.0 6.2 1.1e-171 571.9 1.6 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAG13429.1 - 2.9e-87 292.5 0.0 1.6e-86 290.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAG13429.1 - 1.8e-06 27.1 0.4 1.8e-06 27.1 0.4 1.9 2 0 0 2 2 2 1 Trehalase GDE_C PF06202.14 OAG13429.1 - 0.006 15.6 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Fic PF02661.18 OAG13430.1 - 7.2e-14 52.5 0.0 2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family Glyco_hydro_76 PF03663.14 OAG13433.1 - 6.2e-145 483.3 19.9 7.1e-145 483.1 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG13433.1 - 0.021 13.9 12.3 0.89 8.6 0.1 3.1 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_17 PF00332.18 OAG13435.1 - 0.00013 21.7 1.3 0.00037 20.2 1.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 CorA PF01544.18 OAG13436.1 - 6.1e-11 42.2 0.2 9.9e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein G_path_suppress PF15991.5 OAG13437.1 - 1.7 8.8 9.2 2 8.5 9.2 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor DUF3425 PF11905.8 OAG13439.1 - 1.4e-15 57.3 0.2 7.7e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.25 OAG13440.1 - 1.5e-23 83.3 0.1 4.8e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13440.1 - 1.6e-17 63.8 0.1 3.3e-16 59.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13440.1 - 3.5e-05 23.8 1.0 9.2e-05 22.4 1.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG13440.1 - 0.00047 19.7 0.6 0.0074 15.8 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAO PF01266.24 OAG13442.1 - 1.4e-18 67.6 0.0 2.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.19 OAG13442.1 - 3.6e-11 43.1 0.0 7.5e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase NAD_binding_8 PF13450.6 OAG13442.1 - 0.0039 17.4 0.0 0.0099 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG13442.1 - 0.0081 16.7 0.0 0.91 10.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG13442.1 - 0.014 14.7 0.0 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG13442.1 - 0.034 13.4 0.0 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 OAG13443.1 - 1.4e-07 32.6 0.0 1.9e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG13443.1 - 0.00051 20.0 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RYDR_ITPR PF01365.21 OAG13443.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 RIH domain DUF4267 PF14087.6 OAG13444.1 - 9.3e-17 61.1 6.1 1.3e-16 60.7 6.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Glyco_hydro_130 PF04041.13 OAG13444.1 - 0.032 13.2 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase Sld7_C PF18596.1 OAG13445.1 - 2.4e-28 98.1 0.5 4.9e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 OAG13445.1 - 0.0015 18.8 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain CRPV_capsid PF08762.10 OAG13446.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 CRPV capsid protein like HET PF06985.11 OAG13447.1 - 5.5e-30 104.6 2.3 1.2e-29 103.5 2.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 OAG13448.1 - 8.2e-05 22.4 0.4 0.00027 20.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG13448.1 - 0.0057 16.5 0.1 0.055 13.4 0.0 2.6 2 1 0 2 2 2 1 F-box domain MFS_1 PF07690.16 OAG13450.1 - 9.4e-43 146.5 29.7 9.4e-43 146.5 29.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG13450.1 - 0.006 14.9 5.4 0.0071 14.7 0.7 2.7 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAG13452.1 - 3.2e-05 24.0 8.3 8.1e-05 22.7 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG13452.1 - 0.084 11.9 0.2 4 6.4 0.1 2.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain LXG PF04740.12 OAG13453.1 - 0.021 14.5 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily TPR_14 PF13428.6 OAG13453.1 - 0.039 14.8 0.8 0.12 13.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SbsC_C PF18058.1 OAG13453.1 - 0.088 13.0 0.1 0.31 11.3 0.1 1.7 1 1 0 1 1 1 0 SbsC C-terminal domain Glyoxalase PF00903.25 OAG13454.1 - 8.2e-22 77.8 0.4 4.4e-16 59.3 0.0 2.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG13454.1 - 1.7e-13 50.8 0.1 2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 OAG13454.1 - 1.1e-05 25.7 0.4 0.00032 20.9 0.4 2.5 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 OAG13454.1 - 0.00043 20.4 0.1 1.1 9.4 0.0 3.1 3 1 0 3 3 3 2 Glyoxalase-like domain Gemini_C4 PF01492.17 OAG13454.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Geminivirus C4 protein Zip PF02535.22 OAG13455.1 - 7e-56 189.8 0.3 9.6e-56 189.4 0.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 OAG13456.1 - 8.7e-25 87.6 16.5 1.1e-24 87.3 16.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG13456.1 - 5.6e-09 36.0 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF702 PF05142.12 OAG13458.1 - 0.5 10.8 4.8 2.3 8.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) HET PF06985.11 OAG13459.1 - 3.9e-32 111.6 0.1 6.4e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helo_like_N PF17111.5 OAG13461.1 - 0.00028 20.3 0.1 0.00035 20.0 0.1 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_10 PF13374.6 OAG13462.1 - 6.6e-14 51.2 4.6 0.00027 20.7 0.5 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG13462.1 - 2e-12 47.2 9.2 7.8e-05 22.9 1.1 5.2 2 2 3 6 6 6 4 Tetratricopeptide repeat Clr5 PF14420.6 OAG13462.1 - 3.9e-12 46.2 0.5 1.1e-11 44.8 0.5 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_2 PF07719.17 OAG13462.1 - 7.2e-05 22.6 2.6 0.38 11.0 0.3 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG13462.1 - 0.0078 16.8 0.7 9.7 6.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13462.1 - 0.032 14.0 2.2 0.17 11.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13462.1 - 0.28 11.5 1.7 41 4.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BioW PF03744.13 OAG13462.1 - 1.2 8.6 5.7 0.51 9.9 0.5 2.4 3 0 0 3 3 3 0 6-carboxyhexanoate--CoA ligase Sas10 PF09368.10 OAG13463.1 - 4.1e-29 100.9 9.2 4.1e-29 100.9 9.2 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAG13463.1 - 3.5e-12 46.8 2.3 1.5e-11 44.8 0.0 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF4148 PF13663.6 OAG13463.1 - 1.7 8.9 7.2 0.19 11.9 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) adh_short PF00106.25 OAG13464.1 - 4.6e-21 75.2 0.3 1.3e-20 73.7 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13464.1 - 1.9e-13 50.5 0.6 5.8e-13 48.9 0.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13464.1 - 8.1e-09 35.6 0.7 2.4e-05 24.3 0.1 2.1 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 OAG13464.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAG13464.1 - 0.089 12.7 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG13464.1 - 0.14 12.6 0.0 0.66 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 OAG13464.1 - 0.18 11.3 0.1 0.27 10.6 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 OAG13465.1 - 1.1e-06 28.4 0.3 3.7e-06 26.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG13465.1 - 0.0032 17.3 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAG13465.1 - 1.4 9.5 8.2 44 4.7 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) FAD_binding_4 PF01565.23 OAG13466.1 - 6.8e-23 80.9 0.4 1.2e-22 80.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13466.1 - 4.3e-14 52.3 0.1 1e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like VPS9 PF02204.18 OAG13467.1 - 1.2e-16 60.8 0.1 2.6e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 OAG13467.1 - 5.5e-16 58.4 0.1 2.9e-13 49.7 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG13467.1 - 1.1e-14 54.8 0.1 0.00083 19.9 0.0 5.4 5 1 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG13467.1 - 1.3e-05 25.2 0.0 0.11 13.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAG13467.1 - 2.4e-05 24.8 0.0 0.016 15.8 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) PX PF00787.24 OAG13467.1 - 0.00049 20.1 0.6 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 PX domain Ank PF00023.30 OAG13467.1 - 0.076 13.5 0.2 2.5 8.7 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat Glyco_hydro_43 PF04616.14 OAG13469.1 - 1.4e-72 244.5 1.9 1.7e-72 244.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG13469.1 - 9.5e-12 45.1 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 OAG13469.1 - 0.0012 18.4 0.4 0.0097 15.5 0.0 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Sugar_tr PF00083.24 OAG13470.1 - 1.8e-60 205.1 17.2 3.3e-52 177.9 10.7 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG13470.1 - 6.4e-19 68.1 9.5 6.4e-19 68.1 9.5 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG13470.1 - 1.2e-06 27.3 14.6 0.0019 16.8 3.8 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 OAG13470.1 - 3.8e-05 22.3 8.6 5.6e-05 21.8 4.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAG13470.1 - 0.0002 19.9 1.6 0.00038 19.0 1.6 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 OAG13470.1 - 0.02 13.8 14.3 0.019 13.8 4.5 2.4 2 1 0 2 2 2 0 MFS_1 like family DUF3535 PF12054.8 OAG13470.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) MFS_5 PF05631.14 OAG13470.1 - 0.23 10.3 7.1 0.23 10.4 0.4 3.0 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM DUF485 PF04341.12 OAG13470.1 - 0.32 11.0 5.6 0.092 12.7 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Zn_clus PF00172.18 OAG13471.1 - 6.9e-10 38.9 10.6 1.4e-09 37.9 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG13471.1 - 6.9e-07 28.6 0.1 1.1e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SBF PF01758.16 OAG13472.1 - 5.2e-55 186.1 13.9 5.2e-55 186.1 13.9 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Rhodanese PF00581.20 OAG13473.1 - 2.6e-06 27.9 0.0 4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain AflR PF08493.10 OAG13474.1 - 5.1e-11 42.6 2.8 1.6e-10 41.0 2.6 2.0 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 OAG13474.1 - 2.9e-06 27.3 11.6 6.8e-06 26.1 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 OAG13475.1 - 3.9e-20 72.3 0.1 1.4e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG13475.1 - 2.7e-06 26.9 2.4 0.003 16.8 1.3 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG13475.1 - 0.0003 19.6 0.1 0.021 13.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAG13475.1 - 0.001 18.2 0.1 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG13475.1 - 0.002 17.3 3.3 0.31 10.1 0.2 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.6 OAG13475.1 - 0.0037 16.5 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG13475.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG13475.1 - 0.031 13.5 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 OAG13475.1 - 0.064 13.5 0.1 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 OAG13476.1 - 2.9e-06 26.5 1.9 5.6e-06 25.6 0.4 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain MutS_V PF00488.21 OAG13477.1 - 4.6e-51 173.5 0.0 7.6e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG13477.1 - 1.4e-18 67.8 0.0 2.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OAG13477.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_2 PF07724.14 OAG13478.1 - 6.7e-47 159.8 0.0 3.3e-45 154.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG13478.1 - 1.4e-35 121.3 3.1 1.4e-35 121.3 3.1 2.6 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAG13478.1 - 2.3e-27 94.9 0.1 9.4e-27 92.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAG13478.1 - 9.1e-20 71.4 1.0 7.3e-11 42.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG13478.1 - 3.5e-12 46.5 1.8 4.1e-08 33.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG13478.1 - 3.9e-08 33.2 0.2 8.9e-05 22.2 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 OAG13478.1 - 1e-07 32.5 4.5 0.0017 18.8 0.1 3.9 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 OAG13478.1 - 3e-07 30.8 1.6 0.024 14.9 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.6 OAG13478.1 - 1e-06 28.8 1.0 0.21 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 OAG13478.1 - 2.1e-06 27.3 0.1 0.0086 15.5 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 OAG13478.1 - 2e-05 25.1 2.2 0.043 14.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 OAG13478.1 - 2.4e-05 23.9 0.0 0.16 11.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 OAG13478.1 - 8.3e-05 22.6 7.4 0.18 11.7 0.3 4.2 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OAG13478.1 - 0.00014 21.8 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 OAG13478.1 - 0.00031 20.4 0.1 0.054 13.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 OAG13478.1 - 0.00042 20.1 0.3 0.48 10.1 0.0 3.1 3 0 0 3 3 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OAG13478.1 - 0.001 19.4 0.1 0.94 9.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase ResIII PF04851.15 OAG13478.1 - 0.0011 19.0 0.0 0.63 10.0 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 OAG13478.1 - 0.0011 18.3 0.4 1.1 8.6 0.0 3.2 2 2 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAG13478.1 - 0.0012 19.2 0.2 0.16 12.3 0.1 3.1 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 OAG13478.1 - 0.002 18.3 0.0 0.81 9.9 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 OAG13478.1 - 0.0022 17.0 0.0 0.71 8.7 0.1 2.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OAG13478.1 - 0.0035 17.1 3.1 0.19 11.5 0.0 3.6 4 0 0 4 4 3 1 AAA domain DUF853 PF05872.12 OAG13478.1 - 0.0062 15.2 0.0 0.086 11.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.6 OAG13478.1 - 0.0063 16.3 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG13478.1 - 0.0075 16.3 0.0 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAG13478.1 - 0.008 15.4 0.4 0.37 9.9 0.2 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAG13478.1 - 0.012 15.8 2.4 3.1 8.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OAG13478.1 - 0.012 15.8 7.0 0.29 11.4 0.0 3.9 5 1 0 5 5 3 0 AAA domain UvrD-helicase PF00580.21 OAG13478.1 - 0.021 14.4 5.8 0.17 11.4 0.1 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain OEP PF02321.18 OAG13478.1 - 0.026 14.3 15.7 0.055 13.3 15.7 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein RsgA_GTPase PF03193.16 OAG13478.1 - 0.041 13.8 1.6 7.8 6.4 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_6 PF12774.7 OAG13478.1 - 0.049 12.6 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 OAG13478.1 - 0.053 14.0 2.5 19 5.8 0.0 3.4 3 0 0 3 3 3 0 ABC transporter PduV-EutP PF10662.9 OAG13478.1 - 0.055 13.2 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OAG13478.1 - 0.13 12.0 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 OAG13478.1 - 0.19 11.6 1.5 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Cob_adeno_trans PF01923.18 OAG13478.1 - 0.31 11.2 2.5 0.86 9.7 2.5 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF87 PF01935.17 OAG13478.1 - 0.55 10.3 8.1 28 4.7 0.0 4.0 4 1 1 5 5 4 0 Helicase HerA, central domain GBP_C PF02841.14 OAG13478.1 - 0.57 9.5 11.0 0.97 8.8 11.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.19 OAG13478.1 - 0.98 7.3 5.4 1.3 6.8 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 OAG13478.1 - 1.1 8.6 9.2 1.8 7.8 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAG13478.1 - 1.5 8.6 16.7 0.67 9.8 7.5 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4094 PF13334.6 OAG13478.1 - 1.6 9.2 6.1 0.68 10.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1640 PF07798.11 OAG13478.1 - 2.5 8.1 11.0 5 7.1 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4446 PF14584.6 OAG13478.1 - 3.2 7.7 4.8 8 6.4 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PTPlike_phytase PF14566.6 OAG13478.1 - 5.5 7.1 6.9 4 7.5 4.9 1.7 2 0 0 2 2 1 0 Inositol hexakisphosphate EF1_GNE PF00736.19 OAG13479.1 - 1.3e-32 111.8 3.1 3.1e-32 110.6 3.1 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAG13479.1 - 6.4e-15 55.3 8.3 6.4e-15 55.3 8.3 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region DUF211 PF02680.14 OAG13479.1 - 0.021 15.0 1.0 0.035 14.3 1.0 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 GST_C_3 PF14497.6 OAG13479.1 - 0.047 13.9 0.3 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 OAG13479.1 - 0.072 12.8 4.2 0.11 12.2 4.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HET PF06985.11 OAG13480.1 - 0.031 14.6 0.1 0.049 14.0 0.1 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG13481.1 - 4.2e-35 121.3 34.5 4.2e-35 121.3 34.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG13481.1 - 1.3e-12 47.3 8.4 1.3e-12 47.3 8.4 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter PGG PF13962.6 OAG13482.1 - 6.4 6.6 10.7 4.3 7.2 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function Tetraspanin PF00335.20 OAG13482.1 - 7.4 6.2 13.2 9.3 5.9 4.2 2.4 1 1 1 2 2 2 0 Tetraspanin family Metallophos PF00149.28 OAG13483.1 - 7e-10 39.7 0.1 1.1e-09 39.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG13483.1 - 4.4e-05 23.7 0.5 0.007 16.6 0.5 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF836 PF05768.14 OAG13484.1 - 8.8e-08 32.5 0.0 9.5e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 OAG13484.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OAG13484.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.0 1 0 0 1 1 1 0 F plasmid transfer operon protein CHORD PF04968.12 OAG13485.1 - 1.1e-48 163.7 23.4 3e-25 88.7 7.4 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAG13485.1 - 1.6e-13 51.4 0.1 2.5e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 CS domain adh_short PF00106.25 OAG13486.1 - 1.2e-23 83.6 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13486.1 - 3.6e-21 75.8 0.0 4.7e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13486.1 - 0.00059 19.8 0.0 0.00086 19.3 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG13486.1 - 0.0016 17.9 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG13486.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans PF04082.18 OAG13487.1 - 1.5e-15 57.0 0.1 2.8e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13487.1 - 0.0012 18.9 11.4 0.0012 18.9 11.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_35 PF01301.19 OAG13488.1 - 1.5e-93 313.9 0.0 2.4e-93 313.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG13488.1 - 8.4e-58 193.9 11.3 8.8e-32 110.1 0.2 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAG13488.1 - 6.7e-56 189.0 6.9 1.2e-55 188.2 6.9 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAG13488.1 - 1.4e-22 79.1 1.1 5.1e-22 77.2 0.1 2.4 2 1 1 3 3 3 1 Beta-galactosidase, domain 3 FAD_binding_5 PF00941.21 OAG13491.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase MMgT PF10270.9 OAG13492.1 - 1.2e-27 96.2 0.0 1.5e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Ntox17 PF15524.6 OAG13492.1 - 0.063 13.6 0.8 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Novel toxin 17 Glyco_hydro_cc PF11790.8 OAG13493.1 - 8.5e-53 179.4 0.0 8.7e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MARVEL PF01284.23 OAG13494.1 - 0.013 15.6 6.4 5.1 7.1 1.4 3.4 3 1 0 3 3 3 0 Membrane-associating domain CorA PF01544.18 OAG13495.1 - 3.8e-05 23.1 0.1 6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RelA_SpoT PF04607.17 OAG13496.1 - 5.1e-13 49.3 0.1 1.3e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Ank_4 PF13637.6 OAG13496.1 - 8.5e-05 23.0 0.9 0.0087 16.6 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG13496.1 - 0.00061 20.0 0.2 0.0018 18.6 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG13496.1 - 0.0035 17.9 1.0 0.0066 17.0 0.4 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BUD22 PF09073.10 OAG13496.1 - 0.0058 16.0 27.2 0.011 15.1 27.2 1.4 1 0 0 1 1 1 1 BUD22 Ank_3 PF13606.6 OAG13496.1 - 0.0096 16.4 2.0 2.5 9.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat SDA1 PF05285.12 OAG13496.1 - 0.085 12.3 36.6 0.19 11.2 36.6 1.5 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 OAG13496.1 - 3.8 6.2 4.8 6.2 5.5 4.8 1.2 1 0 0 1 1 1 0 Presenilin Mannosyl_trans3 PF11051.8 OAG13497.1 - 2.4e-52 178.0 0.0 7.5e-33 114.0 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG13497.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Acetyltransf_10 PF13673.7 OAG13499.1 - 5.1e-08 32.9 0.0 9.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG13499.1 - 3.3e-07 30.7 0.3 3.6e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG13499.1 - 0.0014 18.8 0.4 0.002 18.4 0.0 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG13499.1 - 0.015 15.4 0.2 0.028 14.5 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG13499.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein CBM_15 PF03426.14 OAG13499.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Chromo_shadow PF01393.19 OAG13499.1 - 0.14 12.3 0.0 4.2 7.6 0.0 2.7 2 1 0 2 2 2 0 Chromo shadow domain FAD_binding_3 PF01494.19 OAG13500.1 - 6.6e-18 65.1 0.0 1.2e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG13500.1 - 0.0012 18.5 0.0 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG13500.1 - 0.013 14.8 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG13500.1 - 0.015 14.1 0.1 4.6 6.0 0.0 2.9 2 1 0 3 3 3 0 Tryptophan halogenase Mqo PF06039.15 OAG13500.1 - 0.015 13.8 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 OAG13500.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13500.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NACHT PF05729.12 OAG13501.1 - 1.9e-05 24.6 0.0 5.9e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG13501.1 - 4.5e-05 23.9 2.2 0.00016 22.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG13501.1 - 0.0055 17.0 0.0 0.021 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG13501.1 - 0.0078 16.7 0.3 0.068 13.7 0.0 2.6 3 0 0 3 3 3 1 ABC transporter Viral_helicase1 PF01443.18 OAG13501.1 - 0.018 14.8 1.1 0.086 12.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAG13501.1 - 0.043 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Mating_N PF12731.7 OAG13501.1 - 0.055 13.5 0.1 5.2 7.2 0.0 3.6 3 0 0 3 3 3 0 Mating-type protein beta 1 AAA_18 PF13238.6 OAG13501.1 - 0.16 12.5 1.7 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-U1 PF06220.12 OAG13502.1 - 2.4e-08 33.6 0.1 3.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger Pex14_N PF04695.13 OAG13502.1 - 1.7 9.3 6.6 0.61 10.7 1.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hira PF07569.11 OAG13503.1 - 8e-78 261.2 0.0 2.5e-77 259.6 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 OAG13503.1 - 2.6e-29 100.8 16.9 2.8e-05 24.8 0.0 9.0 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13503.1 - 2.3e-12 47.0 0.0 0.1 12.9 0.0 6.2 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAG13503.1 - 1.9e-09 37.1 0.8 4.3e-09 36.0 0.8 1.7 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 OAG13503.1 - 0.0015 17.6 0.7 0.14 11.1 0.0 3.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG13503.1 - 0.0032 17.4 0.2 13 5.8 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 OAG13503.1 - 0.033 12.2 0.1 0.081 10.9 0.0 1.6 2 0 0 2 2 2 0 IKI3 family ORC5_C PF14630.6 OAG13503.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Zn_clus PF00172.18 OAG13504.1 - 6.2e-07 29.4 11.7 1.1e-06 28.7 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG13504.1 - 3.7e-05 22.7 0.1 5.6e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 OAG13505.1 - 1.4e-29 102.9 0.0 1.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IGPS PF00218.21 OAG13505.1 - 0.068 12.3 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DSPc PF00782.20 OAG13505.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF442 PF04273.13 OAG13505.1 - 0.1 12.7 0.1 9.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Asparaginase_2 PF01112.18 OAG13506.1 - 1.4e-48 165.5 3.0 9.5e-32 110.2 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 OAG13507.1 - 6.7e-88 295.0 0.0 2e-85 286.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG13507.1 - 0.00013 20.9 0.0 0.016 14.0 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OAG13507.1 - 0.00023 21.5 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA DUF829 PF05705.14 OAG13507.1 - 0.18 11.7 0.0 0.4 10.5 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) tRNA_U5-meth_tr PF05958.11 OAG13508.1 - 7.4e-12 44.9 0.0 8.2e-11 41.5 0.0 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 OAG13508.1 - 3.3e-05 23.5 0.0 7.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAG13508.1 - 0.00068 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG13508.1 - 0.0013 19.4 0.0 0.0031 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAG13508.1 - 0.0046 16.6 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 OAG13508.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG13508.1 - 0.032 14.9 0.0 0.085 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 OAG13508.1 - 0.053 12.7 0.1 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OAG13508.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Ribosomal_S5_C PF03719.15 OAG13509.1 - 1.3e-22 79.0 0.0 2.8e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OAG13509.1 - 1.2e-16 60.5 0.7 3.1e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 OAG13510.1 - 4.8e-30 103.5 0.3 5.8e-30 103.2 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 NAD_binding_1 PF00175.21 OAG13511.1 - 2.6e-24 85.9 0.0 3.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG13511.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAG13511.1 - 1.4e-06 28.5 0.0 0.0012 19.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain RcsD_ABL PF16359.5 OAG13512.1 - 0.0015 18.6 0.4 0.0062 16.7 0.4 2.1 1 0 0 1 1 1 1 RcsD-ABL domain MFS_1 PF07690.16 OAG13514.1 - 2.4e-28 99.1 53.1 8.7e-15 54.5 21.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG13514.1 - 0.0014 17.3 30.8 0.0053 15.4 12.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein TMEM132D_C PF15706.5 OAG13514.1 - 0.14 12.0 2.5 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term La PF05383.17 OAG13516.1 - 1.6e-18 66.5 0.1 2.7e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 La domain CMS1 PF14617.6 OAG13517.1 - 5.2e-72 242.2 3.2 6.3e-72 241.9 3.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OAG13517.1 - 0.00053 19.8 0.1 0.00067 19.5 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase SPT6_acidic PF14632.6 OAG13517.1 - 0.016 15.8 6.5 0.033 14.8 6.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 SWIRM-assoc_2 PF16496.5 OAG13517.1 - 0.023 13.6 5.4 0.032 13.1 5.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal AP3D1 PF06375.11 OAG13517.1 - 0.034 14.4 6.9 0.056 13.7 6.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TMEM214 PF10151.9 OAG13517.1 - 0.18 10.2 3.5 0.25 9.8 3.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SVIP PF15811.5 OAG13517.1 - 4.2 7.9 11.0 21 5.7 8.1 2.8 3 0 0 3 3 3 0 Small VCP/p97-interacting protein CENP-T_C PF15511.6 OAG13518.1 - 4e-43 145.9 0.1 7.2e-43 145.1 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAG13518.1 - 6.3e-08 32.9 0.1 1.2e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAG13518.1 - 0.002 18.4 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG13518.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OAG13518.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 OAG13518.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SURF1 PF02104.15 OAG13519.1 - 2e-39 135.7 0.0 2.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Macoilin PF09726.9 OAG13520.1 - 0.09 11.3 2.8 0.19 10.3 2.4 1.5 1 1 1 2 2 2 0 Macoilin family DUF908 PF06012.12 OAG13520.1 - 0.15 11.4 7.3 0.18 11.1 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Use1 PF09753.9 OAG13520.1 - 0.56 9.9 7.2 1.3 8.7 7.3 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 dsDNA_bind PF01984.20 OAG13521.1 - 9.2e-40 135.4 12.9 1.2e-39 135.0 12.9 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain LPD15 PF18828.1 OAG13521.1 - 0.039 13.8 0.7 0.058 13.3 0.6 1.5 1 1 0 1 1 1 0 Large polyvalent-protein-associated domain 15 DUF4615 PF15393.6 OAG13521.1 - 0.099 13.2 0.8 0.13 12.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) HET PF06985.11 OAG13522.1 - 7.1e-19 68.6 0.2 4.5e-18 66.0 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG13523.1 - 9e-46 156.4 30.4 9e-46 156.4 30.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG13523.1 - 5.4e-09 35.4 21.3 3.3e-08 32.8 21.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4179 PF13786.6 OAG13523.1 - 0.095 13.2 0.7 19 5.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) FAD_binding_4 PF01565.23 OAG13524.1 - 1.3e-34 118.9 5.4 1.7e-34 118.5 4.5 1.7 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 OAG13524.1 - 2.2e-08 34.1 0.1 4.3e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG13524.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Rsm22 PF09243.10 OAG13525.1 - 3.1e-28 98.8 0.0 5.6e-20 71.8 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 adh_short_C2 PF13561.6 OAG13526.1 - 0.0083 15.7 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13526.1 - 0.075 12.5 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase PH PF00169.29 OAG13527.1 - 0.00063 20.2 0.0 0.0017 18.9 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAG13527.1 - 0.0017 18.7 0.0 0.01 16.2 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain HET PF06985.11 OAG13528.1 - 3.8e-24 85.7 0.3 6.2e-24 85.0 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 OAG13529.1 - 2.6e-22 78.9 2.7 1.1e-12 48.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13529.1 - 8.4e-16 57.1 0.8 1.2e-05 24.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG13529.1 - 1.4e-15 56.1 1.4 0.0042 17.1 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG13529.1 - 1.4e-13 50.2 1.3 4.3e-08 32.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG13529.1 - 1.1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 OAG13529.1 - 7.6e-10 38.1 0.9 7e-05 22.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13529.1 - 8.3e-10 38.1 3.2 0.11 12.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG13529.1 - 2.3e-06 28.1 0.2 1.6e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 OAG13529.1 - 8.4e-05 23.1 3.3 7.4 7.7 0.0 5.8 4 2 2 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG13529.1 - 0.00016 22.2 0.9 0.053 14.2 0.4 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG13529.1 - 0.0034 16.8 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region AAA_22 PF13401.6 OAG13529.1 - 0.0083 16.4 0.0 0.034 14.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 OAG13529.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 OAG13529.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 OAG13529.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ANAPC5 PF12862.7 OAG13529.1 - 0.061 13.4 0.4 4.4 7.4 0.1 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 OAG13529.1 - 0.082 13.6 0.4 29 5.6 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_35 PF14516.6 OAG13529.1 - 0.12 11.2 0.0 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.6 OAG13529.1 - 0.14 12.2 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RPN7 PF10602.9 OAG13529.1 - 0.19 11.4 2.7 11 5.7 0.0 3.3 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 OAG13529.1 - 0.52 10.9 1.9 47 4.6 0.1 3.9 2 2 2 4 4 4 0 Tetratricopeptide repeat Amidase PF01425.21 OAG13532.1 - 2.6e-56 191.5 0.0 7e-52 176.9 0.0 2.2 1 1 1 2 2 2 2 Amidase NAD_binding_9 PF13454.6 OAG13533.1 - 2.1e-34 118.8 0.2 8e-33 113.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG13533.1 - 3.2e-14 52.9 0.0 6.1e-10 38.8 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG13533.1 - 2.2e-09 37.0 0.1 2e-07 30.6 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG13533.1 - 1.1e-06 28.0 0.0 2.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG13533.1 - 3.7e-05 23.5 0.5 0.073 12.6 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 OAG13533.1 - 0.00012 21.3 0.3 0.11 11.6 0.0 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG13533.1 - 0.0011 19.1 0.1 2.2 8.6 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG13533.1 - 0.0094 15.1 1.2 0.88 8.6 0.7 3.2 3 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 OAG13533.1 - 0.036 13.4 0.0 0.098 12.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG13533.1 - 0.042 12.6 1.9 14 4.2 0.0 3.8 4 0 0 4 4 4 0 HI0933-like protein COX7a PF02238.15 OAG13534.1 - 0.14 12.5 0.1 0.56 10.6 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII NmrA PF05368.13 OAG13535.1 - 4.5e-41 140.9 0.0 5.4e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13535.1 - 2.3e-11 44.0 0.0 3.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13535.1 - 6.1e-06 25.9 0.1 2.7e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG13535.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG13535.1 - 0.051 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain JAB PF01398.21 OAG13535.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sec2p PF06428.11 OAG13536.1 - 2.2e-24 85.2 11.4 2.2e-24 85.2 11.4 3.2 3 0 0 3 3 3 2 GDP/GTP exchange factor Sec2p CAV_VP3 PF04771.12 OAG13536.1 - 0.032 14.4 0.8 0.032 14.4 0.8 2.7 3 0 0 3 3 3 0 Chicken anaemia virus VP-3 protein DUF445 PF04286.12 OAG13536.1 - 1.1 9.0 12.2 0.094 12.5 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Spc24 PF08286.11 OAG13536.1 - 1.4 9.2 14.8 19 5.5 0.4 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 OAG13536.1 - 4.1 7.9 5.7 38 4.8 0.2 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OAG13536.1 - 9.9 6.2 10.0 0.9 9.6 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 OAG13537.1 - 2.3e-40 139.3 0.1 3e-40 138.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG13537.1 - 5.6e-23 81.1 1.8 8.4e-23 80.6 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Death_2 PF14786.6 OAG13538.1 - 0.15 12.0 0.2 1.7 8.6 0.0 2.0 1 1 0 2 2 2 0 Tube Death domain LRR_4 PF12799.7 OAG13539.1 - 6.5e-13 48.6 3.8 0.00029 21.2 0.5 3.9 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG13539.1 - 1.2e-09 37.8 9.9 1.5e-06 27.9 3.9 3.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OAG13539.1 - 0.0007 19.5 9.7 5.6 7.3 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 OAG13539.1 - 0.005 16.3 1.5 0.041 13.4 0.5 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OAG13539.1 - 0.046 14.3 10.0 25 5.9 0.3 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat DLH PF01738.18 OAG13542.1 - 6.5e-26 91.2 0.0 8.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 OAG13542.1 - 0.013 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 OAG13542.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2076 PF09849.9 OAG13543.1 - 1e-05 25.7 14.6 1.5e-05 25.2 14.6 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAG13543.1 - 0.00037 20.5 1.6 0.0021 18.2 2.1 1.9 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 OAG13543.1 - 0.013 15.5 0.5 0.021 14.8 0.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Nucleoporin_FG PF13634.6 OAG13543.1 - 5.8 7.8 13.6 20 6.1 13.6 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region MFS18 PF17352.2 OAG13544.1 - 0.06 13.7 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Male Flower Specific protein 18 zf-primase PF09329.11 OAG13544.1 - 0.13 12.0 4.5 4.4 7.2 0.4 2.6 2 0 0 2 2 2 0 Primase zinc finger ApbA_C PF08546.11 OAG13546.1 - 9.7e-33 113.0 0.0 2.2e-32 111.9 0.2 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG13546.1 - 1.3e-21 76.9 0.0 2.5e-21 75.9 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 OAG13547.1 - 2.6e-11 44.0 0.2 2.6e-11 44.0 0.2 3.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Dimerisation2 PF16864.5 OAG13549.1 - 0.00079 19.3 0.1 0.0025 17.7 0.0 1.8 1 1 1 2 2 2 1 Dimerisation domain DUF3425 PF11905.8 OAG13550.1 - 1.5e-14 54.0 0.1 2.6e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG13550.1 - 0.0057 16.7 8.8 0.016 15.3 8.8 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG13550.1 - 0.13 12.4 9.8 2.7 8.1 8.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Isochorismatase PF00857.20 OAG13551.1 - 5.6e-21 75.5 0.1 6.8e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family HisKA_3 PF07730.13 OAG13551.1 - 0.079 13.5 0.3 0.19 12.3 0.3 1.6 1 0 0 1 1 1 0 Histidine kinase ECH_1 PF00378.20 OAG13552.1 - 1.3e-50 172.1 0.0 1.9e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG13552.1 - 2.9e-23 82.9 0.1 1.1e-19 71.2 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG13552.1 - 0.00097 19.1 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 UCH PF00443.29 OAG13553.1 - 9.8e-45 153.0 0.0 1.8e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG13553.1 - 6.2e-08 32.6 0.0 3.9e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4 PF00097.25 OAG13554.1 - 5.6e-08 32.5 5.9 9.6e-08 31.8 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG13554.1 - 2.1e-07 30.8 2.8 2.5e-07 30.6 1.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG13554.1 - 5e-07 29.5 3.9 1.2e-05 25.0 1.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG13554.1 - 7.7e-06 25.7 4.9 1.5e-05 24.8 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG13554.1 - 2e-05 24.5 5.2 8e-05 22.5 5.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG13554.1 - 2e-05 24.8 5.8 3.8e-05 23.9 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAG13554.1 - 4.7e-05 23.5 3.3 0.00011 22.3 3.4 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING TerY_C PF15616.6 OAG13554.1 - 0.0094 16.1 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain Prok-RING_4 PF14447.6 OAG13554.1 - 0.083 12.8 8.6 0.84 9.5 8.6 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG13554.1 - 0.1 12.9 4.4 0.58 10.5 4.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rxt3 PF08642.10 OAG13554.1 - 0.22 12.3 3.1 4.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Methyltrn_RNA_3 PF02598.17 OAG13556.1 - 2.9e-96 322.3 0.0 3.6e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase TIP41 PF04176.13 OAG13556.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP41-like family BB_PF PF18063.1 OAG13557.1 - 0.002 17.7 0.6 0.0033 17.1 0.6 1.3 1 0 0 1 1 1 1 Beta barrel Pore-forming domain GST_N_3 PF13417.6 OAG13559.1 - 2e-08 34.5 0.0 4.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG13559.1 - 8.5e-07 28.9 0.1 1.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG13559.1 - 2.2e-05 24.7 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG13559.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG13560.1 - 3.4e-13 49.7 0.0 7.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG13560.1 - 2e-11 44.1 0.0 4.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG13560.1 - 3e-08 33.8 0.0 1e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG13560.1 - 4.6e-07 30.0 0.0 7.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG13560.1 - 7.5e-05 22.7 0.0 0.00032 20.7 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG13560.1 - 0.00014 21.9 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HET PF06985.11 OAG13561.1 - 1.5e-28 100.0 0.1 1.6e-28 99.9 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG13562.1 - 3.5e-27 95.1 1.9 1.2e-25 90.1 1.6 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13562.1 - 4.5e-21 75.5 0.2 5.5e-20 71.9 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13562.1 - 4.4e-06 26.7 1.1 1.2e-05 25.3 1.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG13562.1 - 0.00053 19.5 0.4 0.001 18.6 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family QRPTase_C PF01729.19 OAG13562.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain adh_short_C2 PF13561.6 OAG13563.1 - 0.00025 20.7 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13563.1 - 0.0016 18.0 0.8 0.043 13.3 0.5 2.2 1 1 1 2 2 2 2 short chain dehydrogenase Ank_2 PF12796.7 OAG13564.1 - 1.7e-07 31.7 0.0 1.1e-06 29.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Helo_like_N PF17111.5 OAG13564.1 - 1.8e-06 27.5 0.1 4.8e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 OAG13564.1 - 5.6e-05 23.2 0.1 0.0017 18.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OAG13564.1 - 6.5e-05 23.4 0.1 0.00049 20.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG13564.1 - 0.0015 18.8 0.0 0.0044 17.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4913 PF16259.5 OAG13564.1 - 0.0069 16.4 0.9 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4913) Ank PF00023.30 OAG13564.1 - 0.02 15.4 0.2 0.16 12.5 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat SesA PF17107.5 OAG13564.1 - 0.058 13.6 0.2 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3716 PF12511.8 OAG13564.1 - 0.28 11.3 4.0 0.87 9.7 4.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) HET PF06985.11 OAG13565.1 - 1.2e-15 58.2 0.0 2.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.20 OAG13566.1 - 1.7e-15 57.4 0.1 6.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG13566.1 - 8.3e-15 56.0 0.0 1.6e-14 55.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG13566.1 - 1.5e-06 27.7 0.0 0.0027 17.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 EHN PF06441.12 OAG13566.1 - 0.038 14.4 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus FKBP_C PF00254.28 OAG13566.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase HET PF06985.11 OAG13567.1 - 2.3e-33 115.6 1.0 3.7e-33 115.0 1.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fructosamin_kin PF03881.14 OAG13568.1 - 2.3e-75 253.5 0.0 2.7e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG13568.1 - 0.0029 17.6 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG13568.1 - 0.0059 16.0 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAG13568.1 - 0.025 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Cutinase PF01083.22 OAG13569.1 - 5.4e-41 140.5 3.9 6.3e-41 140.3 3.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG13569.1 - 0.00048 19.7 0.1 0.00061 19.4 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 OAG13569.1 - 0.0011 18.7 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_9 PF10081.9 OAG13569.1 - 0.022 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_2 PF02230.16 OAG13569.1 - 0.05 13.4 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 OAG13569.1 - 0.059 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.8 OAG13569.1 - 0.063 12.5 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 OAG13571.1 - 4.3e-23 82.1 0.0 5.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG13571.1 - 2.2e-14 53.8 3.6 2.7e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG13571.1 - 6e-08 32.3 3.0 0.0041 16.4 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG13571.1 - 1.1e-06 28.0 0.5 1.1e-06 28.0 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG13571.1 - 1.3e-06 27.4 1.8 8.8e-06 24.7 1.8 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 OAG13571.1 - 6.5e-06 26.6 1.3 0.097 13.2 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG13571.1 - 1.6e-05 24.5 0.3 2.2e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG13571.1 - 2.7e-05 23.4 1.3 7.6e-05 21.9 1.4 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG13571.1 - 6.3e-05 22.0 1.1 0.15 10.9 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OAG13571.1 - 6.9e-05 23.0 2.3 0.00018 21.6 2.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG13571.1 - 0.00021 20.5 0.7 0.0004 19.6 0.7 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 OAG13571.1 - 0.00022 20.4 0.0 0.0007 18.7 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG13571.1 - 0.00082 18.7 0.0 0.045 13.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG13571.1 - 0.0011 18.4 4.4 0.1 11.9 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG13571.1 - 0.014 15.4 1.4 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG13571.1 - 0.035 13.3 0.4 0.058 12.6 0.4 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 OAG13571.1 - 0.058 13.3 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 OAG13572.1 - 5.9e-43 147.2 0.3 7.5e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG13572.1 - 8.9e-07 28.1 0.0 1.9e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 OAG13572.1 - 0.019 14.2 0.0 0.06 12.6 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Caudal_act PF04731.12 OAG13574.1 - 0.069 13.5 3.3 0.15 12.4 3.3 1.7 1 1 0 1 1 1 0 Caudal like protein activation region NmrA PF05368.13 OAG13575.1 - 2.5e-35 122.1 0.0 3.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13575.1 - 9.3e-21 74.5 0.0 1.6e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13575.1 - 1.2e-07 31.4 0.0 9.3e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG13575.1 - 0.0019 17.3 0.0 0.0059 15.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG13575.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OAG13575.1 - 0.023 15.3 0.1 0.05 14.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UPF0180 PF03698.13 OAG13575.1 - 0.18 12.0 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Ank_5 PF13857.6 OAG13576.1 - 1e-08 35.2 0.2 0.07 13.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG13576.1 - 3.5e-07 30.0 0.1 0.76 10.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OAG13576.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG13576.1 - 0.00044 20.7 0.7 0.22 12.2 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG13576.1 - 0.0011 19.3 0.4 0.027 14.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat MS_channel PF00924.18 OAG13577.1 - 4.8e-13 49.1 0.1 6.5e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAG13577.1 - 6.4e-05 22.2 0.6 0.00018 20.8 0.6 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG13577.1 - 0.00013 21.6 0.1 0.00046 19.9 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain Na_Ca_ex PF01699.24 OAG13577.1 - 0.003 17.5 1.3 0.0057 16.6 1.3 1.5 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF3708 PF12501.8 OAG13577.1 - 0.0034 17.2 0.5 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 Phosphate ATP-binding cassette transporter EF-hand_7 PF13499.6 OAG13577.1 - 0.026 14.9 0.5 0.083 13.4 0.2 2.1 2 1 0 2 2 2 0 EF-hand domain pair Flp1_like PF16982.5 OAG13577.1 - 0.031 13.7 0.2 0.082 12.3 0.2 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain ANAPC2 PF08672.11 OAG13577.1 - 0.26 11.8 1.5 4.6 7.8 0.1 3.0 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 zf-3CxxC PF13695.6 OAG13580.1 - 5e-20 71.8 3.5 1.5e-17 63.9 0.3 2.6 3 0 0 3 3 3 2 Zinc-binding domain zf-C2H2_jaz PF12171.8 OAG13580.1 - 5.4e-10 39.3 8.4 3.1e-05 24.1 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG13580.1 - 4.4e-07 30.1 11.4 9.1e-05 22.7 1.5 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG13580.1 - 0.00027 20.9 9.5 0.011 15.7 0.8 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG13580.1 - 0.0015 19.2 1.5 0.015 16.1 0.2 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG13580.1 - 0.0033 17.2 6.4 0.12 12.1 0.2 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 OAG13580.1 - 0.0096 16.3 0.3 0.0096 16.3 0.3 4.6 5 0 0 5 5 4 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG13580.1 - 0.022 15.1 1.8 2.3 8.6 0.6 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-3CxxC_2 PF17180.4 OAG13580.1 - 0.099 13.4 11.5 0.67 10.7 0.0 4.3 4 1 0 4 4 4 0 Zinc-binding domain EGF_CA PF07645.15 OAG13580.1 - 0.099 12.9 7.7 0.47 10.7 0.1 3.1 3 0 0 3 3 3 0 Calcium-binding EGF domain PRNT PF15174.6 OAG13580.1 - 1.6 8.8 4.3 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 Prion-related protein testis-specific p450 PF00067.22 OAG13581.1 - 2.8e-63 214.3 0.0 3.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 OAG13583.1 - 4.1e-33 114.8 0.1 1.2e-32 113.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 OAG13583.1 - 2.8e-16 60.0 5.4 4.5e-16 59.3 5.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAG13583.1 - 9.5e-07 28.5 0.2 0.00025 20.5 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG13583.1 - 8.6e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OAG13583.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 OAG13583.1 - 0.0014 18.5 0.8 0.0031 17.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG13583.1 - 0.0061 16.3 1.5 0.03 14.0 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG13583.1 - 0.0069 16.5 0.1 0.023 14.8 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG13583.1 - 0.0072 16.6 0.1 0.022 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG13583.1 - 0.0084 16.5 0.1 0.021 15.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OAG13583.1 - 0.039 13.7 0.3 0.1 12.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAG13583.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 OAG13583.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 OAG13583.1 - 0.083 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Rota_VP4_MID PF17477.2 OAG13583.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain PBP1_TM PF14812.6 OAG13583.1 - 0.11 12.9 1.5 0.26 11.7 1.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF87 PF01935.17 OAG13583.1 - 0.11 12.5 0.3 0.3 11.1 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 OAG13583.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OAG13583.1 - 0.16 12.0 0.3 0.38 10.8 0.3 1.8 1 1 0 1 1 1 0 Dynamin family Cellulase PF00150.18 OAG13584.1 - 6e-15 55.4 0.5 8.6e-15 54.9 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LGFP PF08310.11 OAG13584.1 - 0.54 10.8 3.0 0.6 10.7 0.7 2.2 3 0 0 3 3 3 0 LGFP repeat HET PF06985.11 OAG13585.1 - 8.1e-28 97.6 0.0 1.1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_Rpb2_4 PF04566.13 OAG13585.1 - 0.097 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Ub-Mut7C PF14451.6 OAG13586.1 - 0.081 12.8 0.0 1 9.3 0.0 2.2 1 1 1 2 2 2 0 Mut7-C ubiquitin HET PF06985.11 OAG13587.1 - 9.7e-24 84.4 0.2 1.7e-23 83.6 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_25 PF13649.6 OAG13588.1 - 6.6e-20 71.6 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG13588.1 - 5.7e-18 65.4 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG13588.1 - 1.6e-13 50.8 0.0 3.3e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG13588.1 - 1.5e-10 41.1 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG13588.1 - 8.4e-08 32.9 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG13588.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG13588.1 - 0.00034 20.0 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG13588.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 OAG13588.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 OAG13588.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FmrO PF07091.11 OAG13588.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MFS_1 PF07690.16 OAG13589.1 - 1e-31 110.2 35.0 1e-31 110.2 35.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3237 PF11578.8 OAG13590.1 - 9.8e-37 126.1 0.0 1.1e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) LUD_dom PF02589.15 OAG13590.1 - 0.21 11.3 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 LUD domain FAD_binding_3 PF01494.19 OAG13591.1 - 2.2e-23 83.1 0.0 2.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG13591.1 - 1.8e-08 34.0 0.1 0.00047 19.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13591.1 - 4.9e-08 33.1 0.5 1.2e-07 31.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG13591.1 - 1.5e-07 31.4 7.1 0.0025 17.4 3.8 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG13591.1 - 6.8e-06 25.4 4.4 8.4e-05 21.8 4.4 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG13591.1 - 1.3e-05 24.5 3.9 1.3e-05 24.5 3.9 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG13591.1 - 3.5e-05 24.3 0.5 0.00053 20.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG13591.1 - 8.1e-05 21.5 4.3 0.0016 17.2 1.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OAG13591.1 - 0.00045 19.7 0.1 0.00061 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG13591.1 - 0.0018 17.5 1.7 0.0043 16.2 1.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Rossmann-like PF10727.9 OAG13591.1 - 0.0024 17.8 0.8 0.0048 16.8 0.1 1.8 2 0 0 2 2 2 1 Rossmann-like domain Glyco_transf_4 PF13439.6 OAG13591.1 - 0.011 15.8 0.4 0.022 14.8 0.4 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_9 PF13454.6 OAG13591.1 - 0.042 13.8 3.1 0.77 9.7 3.1 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG13591.1 - 0.049 12.9 2.0 0.062 12.5 0.5 1.8 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 OAG13591.1 - 0.053 13.5 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 OAG13591.1 - 0.19 10.8 0.0 5.1 6.1 0.0 2.6 3 0 0 3 3 3 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG13591.1 - 0.22 10.7 4.6 0.32 10.2 2.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG13591.1 - 0.26 11.1 1.2 0.5 10.2 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAG13592.1 - 1.6e-34 119.2 1.2 2.9e-34 118.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13592.1 - 5.4e-09 36.0 11.9 9.7e-09 35.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 OAG13593.1 - 3.4e-26 90.7 0.4 1.3e-16 60.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG13593.1 - 4.5e-08 33.1 0.4 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG13593.1 - 8.7e-06 25.3 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG13593.1 - 5.3e-05 23.3 0.0 0.00017 21.7 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 OAG13593.1 - 0.005 16.4 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 1 Cupin DMSP_lyase PF16867.5 OAG13593.1 - 0.019 14.6 0.0 0.019 14.6 0.0 1.9 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase ARD PF03079.14 OAG13593.1 - 0.029 14.5 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family FAA_hydrolase PF01557.18 OAG13594.1 - 1.2e-57 195.1 0.0 1.6e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 OAG13595.1 - 3.5e-114 381.9 0.6 4.2e-114 381.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG13595.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4806 PF16064.5 OAG13595.1 - 0.17 12.2 0.0 0.5 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) RPE65 PF03055.15 OAG13596.1 - 2.1e-104 350.3 0.0 2.4e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LysM PF01476.20 OAG13598.1 - 2e-12 46.9 0.0 2.4e-05 24.3 0.0 4.2 4 0 0 4 4 4 3 LysM domain TPPK_C PF12555.8 OAG13598.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Astacin PF01400.24 OAG13599.1 - 0.00022 20.9 0.8 0.37 10.4 0.7 3.1 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 OAG13599.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAG13599.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAG13599.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG13599.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_18 PF00704.28 OAG13600.1 - 1e-67 229.1 0.0 1.3e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG13600.1 - 4.7e-09 36.6 7.5 4.7e-09 36.6 7.5 2.8 2 1 0 2 2 2 1 Chitin recognition protein Fungal_lectin_2 PF18647.1 OAG13602.1 - 6.7e-38 129.3 6.7 2.8e-37 127.2 6.4 2.2 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 OAG13602.1 - 1.8e-10 41.5 0.2 1.1e-08 35.7 0.0 2.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG13602.1 - 2.8e-07 30.7 0.0 6.6e-06 26.2 0.0 2.5 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 OAG13603.1 - 4.1e-37 127.9 23.0 4.1e-37 127.9 23.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sulf_coat_C PF12193.8 OAG13603.1 - 0.064 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal PRT_C PF08372.10 OAG13603.1 - 0.23 11.2 0.8 0.51 10.1 0.8 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal SirB PF04247.12 OAG13603.1 - 0.87 9.7 7.8 0.84 9.7 0.3 2.6 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB HpcH_HpaI PF03328.14 OAG13604.1 - 2.2e-33 115.2 0.3 2.8e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 OAG13604.1 - 0.0014 17.8 0.1 0.016 14.3 0.1 2.4 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ribonuc_L-PSP PF01042.21 OAG13605.1 - 6e-22 77.9 0.0 7.3e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2OG-FeII_Oxy PF03171.20 OAG13606.1 - 2.7e-12 47.0 0.0 4.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG13606.1 - 2.6e-09 37.8 0.0 6.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pam16 PF03656.13 OAG13607.1 - 6.4e-06 26.2 0.0 7.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 OAG13607.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Optomotor-blind PF11078.8 OAG13607.1 - 0.14 12.7 0.6 0.21 12.2 0.6 1.2 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region Ribosomal_L24e PF01246.20 OAG13608.1 - 8.7e-32 109.2 5.9 8.7e-32 109.2 5.9 2.3 2 0 0 2 2 2 1 Ribosomal protein L24e DUF720 PF05302.11 OAG13608.1 - 0.0044 16.9 0.4 0.25 11.2 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF720) XhlA PF10779.9 OAG13608.1 - 0.95 9.7 3.6 1.3 9.3 2.5 1.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF2175 PF09943.9 OAG13608.1 - 6.1 7.2 8.5 7.2 7.0 0.4 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GST_N_3 PF13417.6 OAG13609.1 - 5.7e-12 45.9 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG13609.1 - 8.2e-05 22.8 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG13609.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG13609.1 - 0.085 13.6 0.0 0.38 11.5 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain FAD_binding_3 PF01494.19 OAG13611.1 - 2.4e-21 76.4 0.3 6.3e-16 58.6 0.2 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG13611.1 - 0.00016 21.8 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG13611.1 - 0.00097 19.6 0.0 0.72 10.4 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG13611.1 - 0.0079 15.3 0.1 0.48 9.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG13611.1 - 0.016 14.4 0.2 0.69 9.1 0.2 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG13611.1 - 0.094 11.6 0.3 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG13611.1 - 0.13 11.5 0.0 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M14 PF00246.24 OAG13612.1 - 4.3e-16 59.6 0.0 6.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase HEPN_Toprim_N PF18871.1 OAG13612.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Aldolase_II PF00596.21 OAG13613.1 - 7.8e-25 87.9 0.0 9.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 OAG13614.1 - 2.1e-28 99.1 0.0 4.4e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13614.1 - 3e-09 36.9 13.0 5.6e-09 36.0 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 OAG13615.1 - 5.4e-15 55.7 0.1 8.3e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG13615.1 - 3e-10 41.1 0.0 3.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG13615.1 - 3.3e-09 36.4 0.1 7.4e-09 35.2 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 OAG13615.1 - 0.003 16.7 0.2 0.0061 15.7 0.0 1.5 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Thioesterase PF00975.20 OAG13615.1 - 0.018 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 OAG13615.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1100 PF06500.11 OAG13615.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.12 OAG13615.1 - 0.082 12.8 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 OAG13615.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 OAG13615.1 - 0.13 11.8 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Cutinase PF01083.22 OAG13616.1 - 6e-20 71.9 1.5 6.9e-20 71.7 1.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG13616.1 - 0.002 17.7 0.2 0.0029 17.2 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG13616.1 - 0.067 13.1 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PHD PF00628.29 OAG13617.1 - 1e-10 41.3 10.5 2.6e-10 40.0 10.5 1.8 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 OAG13617.1 - 0.005 16.6 2.7 0.011 15.6 0.4 2.2 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain AvrM-A PF18241.1 OAG13617.1 - 0.24 11.8 5.2 0.49 10.8 1.0 2.5 2 0 0 2 2 2 0 Flax-rust effector AvrM-A MAGE PF01454.19 OAG13618.1 - 7.9e-59 198.9 0.0 1.1e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 MAGE family Chalcone_2 PF16035.5 OAG13619.1 - 8.6e-68 228.1 0.0 1.3e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAG13619.1 - 0.0016 18.6 0.1 0.0085 16.2 0.0 2.0 2 0 0 2 2 2 1 Chalcone isomerase-like MFS_1 PF07690.16 OAG13620.1 - 1.7e-36 125.9 28.4 1.7e-36 125.9 28.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 OAG13620.1 - 6.4 7.0 6.0 1.7 8.9 0.0 3.1 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit rhaM PF05336.13 OAG13622.1 - 1.5e-36 124.8 0.1 1.6e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase CLU PF13236.6 OAG13623.1 - 4.4e-73 245.8 0.0 9.9e-73 244.6 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAG13623.1 - 2.8e-49 167.5 3.5 3.8e-49 167.1 0.0 2.6 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAG13623.1 - 2.3e-25 88.7 12.9 6.7e-13 48.7 0.1 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.6 OAG13623.1 - 8e-24 83.8 0.9 3.9e-23 81.6 0.5 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 OAG13623.1 - 1.2e-19 69.5 2.5 3.1e-05 23.7 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF727 PF05303.12 OAG13623.1 - 9.1e-06 25.7 0.0 2.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 OAG13623.1 - 0.0062 16.6 2.3 1.9 8.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat 3-alpha PF03475.14 OAG13623.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 3-alpha domain Spt20 PF12090.8 OAG13623.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.3 3 0 0 3 3 2 0 Spt20 family CRT10 PF08728.10 OAG13623.1 - 1.7 6.7 7.0 2.5 6.2 7.0 1.1 1 0 0 1 1 1 0 CRT10 DDHD PF02862.17 OAG13623.1 - 2.1 8.4 12.1 1.5 8.9 9.4 2.1 2 0 0 2 2 2 0 DDHD domain SAPS PF04499.15 OAG13623.1 - 4.3 6.0 13.9 1.3 7.8 9.7 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 OAG13623.1 - 5.5 6.7 12.0 0.59 9.9 7.3 1.9 2 0 0 2 2 2 0 AAA domain PGA2 PF07543.12 OAG13623.1 - 8 6.4 27.0 1.6 8.7 22.8 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Presenilin PF01080.17 OAG13623.1 - 9.7 4.8 19.8 20 3.8 19.8 1.4 1 0 0 1 1 1 0 Presenilin AAA_16 PF13191.6 OAG13624.1 - 2.1e-06 28.2 0.2 8.5e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OAG13624.1 - 0.072 12.6 0.1 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 OAG13624.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Terminase_6C PF17289.2 OAG13624.1 - 8.8 6.4 9.3 0.56 10.3 0.1 3.1 3 1 1 4 4 4 0 Terminase RNaseH-like domain P16-Arc PF04699.14 OAG13625.1 - 1.4e-49 168.4 0.0 1.5e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) HET PF06985.11 OAG13629.1 - 1.7e-07 31.7 0.0 1.6e-06 28.6 0.0 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pmp3 PF01679.17 OAG13630.1 - 3.7e-20 71.8 11.9 4.2e-20 71.7 11.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ASXH PF13919.6 OAG13633.1 - 0.058 13.4 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Asx homology domain Sec39 PF08314.11 OAG13634.1 - 1.2e-261 870.5 0.3 1.3e-261 870.3 0.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF4097 PF13349.6 OAG13635.1 - 0.00034 20.1 9.9 0.0054 16.1 0.7 2.3 1 1 1 2 2 2 2 Putative adhesin DUF4451 PF14616.6 OAG13636.1 - 2.8e-22 79.2 0.0 6.1e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) NmrA PF05368.13 OAG13637.1 - 7.1e-15 55.2 0.0 9.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13637.1 - 3.6e-08 33.5 0.0 6.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fun_ATP-synt_8 PF05933.13 OAG13638.1 - 3.6e-19 68.6 7.6 5e-19 68.2 7.6 1.2 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) Phospholip_A2_3 PF09056.11 OAG13639.1 - 1.3e-23 83.7 2.4 1.6e-23 83.5 2.4 1.0 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MFS_1 PF07690.16 OAG13640.1 - 2.3e-39 135.3 32.3 5.7e-34 117.6 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG13640.1 - 4.2e-05 22.0 0.0 0.00024 19.6 0.0 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family EptA_B_N PF08019.12 OAG13641.1 - 0.46 10.4 3.8 11 5.9 0.1 2.7 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Chitin_bind_1 PF00187.19 OAG13642.1 - 2.3e-08 34.3 21.4 2.7e-08 34.2 21.4 1.1 1 0 0 1 1 1 1 Chitin recognition protein DUF1772 PF08592.11 OAG13644.1 - 9.5e-31 106.9 3.7 1.3e-30 106.5 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 OAG13644.1 - 0.11 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 DUF1993 PF09351.10 OAG13645.1 - 9.7e-16 58.3 0.0 1.1e-15 58.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) IDEAL PF08858.10 OAG13645.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IDEAL domain Zn_clus PF00172.18 OAG13647.1 - 1.8e-05 24.8 12.3 1.8e-05 24.8 12.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG13648.1 - 3.1e-36 125.1 0.0 1.1e-34 120.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG13649.1 - 1.6e-67 228.2 0.0 2e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5311 PF17238.2 OAG13649.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Aldedh PF00171.22 OAG13650.1 - 1.7e-136 455.4 0.3 1.9e-136 455.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG13650.1 - 0.013 15.0 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) p450 PF00067.22 OAG13651.1 - 4.2e-59 200.5 0.0 5.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 OAG13654.1 - 1e-15 57.4 0.0 5.1e-15 55.1 0.0 2.2 1 1 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.26 OAG13655.1 - 2.1e-62 211.0 0.2 1e-61 208.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG13655.1 - 2.4e-57 193.8 0.0 7e-57 192.2 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 OAG13655.1 - 1.6e-54 185.1 0.0 3.4e-54 184.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG13655.1 - 7e-51 173.6 1.8 1.5e-50 172.5 1.8 1.5 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG13655.1 - 1.5e-32 112.1 0.2 3.3e-32 111.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG13655.1 - 4.9e-17 62.5 0.0 1.3e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG13655.1 - 4.6e-16 59.3 0.0 1.5e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 OAG13655.1 - 8.5e-14 52.8 0.0 5.5e-11 43.7 0.0 3.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG13655.1 - 1.1e-11 44.5 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 OAG13655.1 - 2.6e-11 43.7 0.0 7.3e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OAG13655.1 - 3.2e-10 40.1 0.1 5.6e-09 36.1 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG13655.1 - 1e-08 35.7 0.0 4.1e-08 33.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 OAG13655.1 - 1.6e-08 34.4 0.0 4.1e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 OAG13655.1 - 1.5e-07 31.9 0.0 5.8e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG13655.1 - 2.6e-06 27.3 0.0 1.5e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG13655.1 - 2.1e-05 24.0 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 OAG13655.1 - 0.00044 20.6 0.9 0.0013 19.1 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 OAG13655.1 - 0.024 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 OAG13655.1 - 0.037 13.4 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Thiolase, N-terminal domain LRR_6 PF13516.6 OAG13656.1 - 1.2e-12 46.8 19.9 0.0051 16.8 0.0 8.4 10 0 0 10 10 10 4 Leucine Rich repeat F-box-like PF12937.7 OAG13656.1 - 1.6e-12 47.1 0.1 3.1e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG13656.1 - 2.7e-10 39.8 0.1 9.9e-10 38.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAG13656.1 - 2.6e-05 24.5 8.9 0.046 14.1 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) PRANC PF09372.10 OAG13656.1 - 0.034 14.5 0.0 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 PRANC domain LRR_1 PF00560.33 OAG13656.1 - 0.1 13.2 22.1 2.9 8.8 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich Repeat TPP_enzyme_N PF02776.18 OAG13656.1 - 0.18 11.4 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2OG-FeII_Oxy_2 PF13532.6 OAG13657.1 - 1.8e-13 51.1 0.0 5.2e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDH-cyt PF16010.5 OAG13658.1 - 1.5e-29 102.9 3.7 3e-29 102.0 3.7 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAG13658.1 - 1.1e-06 28.8 0.3 2.5e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 OAG13658.1 - 0.0058 16.8 15.9 0.01 16.0 15.9 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PT PF04886.12 OAG13658.1 - 0.036 13.6 0.5 0.11 12.1 0.5 1.8 1 0 0 1 1 1 0 PT repeat DUF4834 PF16118.5 OAG13658.1 - 0.45 11.5 2.1 0.82 10.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Rtt106 PF08512.12 OAG13660.1 - 1.6e-26 92.5 0.0 2.7e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Lectin_N PF03954.14 OAG13662.1 - 0.02 14.6 0.3 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain PufQ PF05398.11 OAG13662.1 - 0.21 11.7 2.7 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF2569 PF10754.9 OAG13662.1 - 4.2 7.8 11.0 22 5.5 7.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) CDC45 PF02724.14 OAG13663.1 - 2.9 6.1 6.2 5.5 5.1 6.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Fe-ADH PF00465.19 OAG13664.1 - 9.9e-104 347.0 0.0 1.3e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG13664.1 - 2.1e-14 53.8 0.0 2.3e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase PH PF00169.29 OAG13665.1 - 0.014 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 PH domain 2OG-FeII_Oxy_2 PF13532.6 OAG13666.1 - 3.5e-31 108.9 0.0 1.3e-30 107.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 OAG13667.1 - 7.1e-66 222.3 0.0 1.1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13667.1 - 1.5e-31 109.6 0.0 2.5e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 OAG13667.1 - 6.2e-13 49.2 0.0 8.3e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 UBA PF00627.31 OAG13667.1 - 9.9e-05 22.2 0.0 0.00028 20.7 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Haspin_kinase PF12330.8 OAG13667.1 - 0.005 15.8 0.1 0.077 11.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OAG13667.1 - 0.039 13.3 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAG13667.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG13667.1 - 0.22 10.9 0.2 0.42 9.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.22 OAG13668.1 - 1.2e-12 48.4 0.1 1.1e-11 45.3 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG13668.1 - 1.3e-11 44.8 0.0 1e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CTD PF12815.7 OAG13668.1 - 0.32 11.6 6.4 1.1 9.9 3.9 2.6 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 WD40 PF00400.32 OAG13670.1 - 1.3e-12 48.0 6.9 6.4e-05 23.7 0.2 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13670.1 - 1.6e-11 44.3 0.1 0.00014 22.1 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG13670.1 - 0.0043 17.0 0.0 0.077 12.9 0.0 2.1 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAG13670.1 - 0.0064 14.5 0.0 0.074 11.0 0.0 1.9 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.16 OAG13670.1 - 0.016 13.7 0.0 0.098 11.2 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain Utp8 PF10395.9 OAG13670.1 - 0.017 13.7 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 Utp8 family PD40 PF07676.12 OAG13670.1 - 0.045 13.7 0.0 18 5.4 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat YpsA PF06908.11 OAG13670.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family EF_assoc_2 PF08356.12 OAG13671.1 - 2.4e-33 114.0 0.0 5.3e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 OAG13671.1 - 2e-29 101.0 0.3 4.6e-29 99.8 0.3 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 OAG13671.1 - 9e-25 87.1 0.0 8.4e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG13671.1 - 1.1e-14 54.7 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG13671.1 - 3.9e-09 36.6 0.0 2.7e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG13671.1 - 2.9e-06 27.3 0.0 0.22 11.4 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase EF-hand_6 PF13405.6 OAG13671.1 - 1.7e-05 24.4 2.3 0.022 14.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAG13671.1 - 6.5e-05 22.2 1.5 0.18 11.4 0.8 2.8 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 OAG13671.1 - 0.00011 22.6 0.1 0.092 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAG13671.1 - 0.00025 20.7 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG13671.1 - 0.00038 20.7 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG13671.1 - 0.00063 20.3 0.1 0.3 11.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 OAG13671.1 - 0.0009 19.3 0.1 0.44 10.6 0.0 2.7 3 0 0 3 3 2 1 Dynamin family RNA_helicase PF00910.22 OAG13671.1 - 0.00093 19.6 0.0 0.52 10.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase EF-hand_7 PF13499.6 OAG13671.1 - 0.002 18.6 0.6 0.21 12.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_24 PF13479.6 OAG13671.1 - 0.0051 16.6 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.6 OAG13671.1 - 0.0058 16.1 3.5 0.17 11.5 2.2 2.7 2 0 0 2 2 2 1 EF hand DUF815 PF05673.13 OAG13671.1 - 0.013 14.7 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG13671.1 - 0.02 14.4 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 OAG13671.1 - 0.022 14.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 OAG13671.1 - 0.024 15.2 0.1 0.92 10.1 0.1 2.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 OAG13671.1 - 0.025 14.0 0.0 11 5.5 0.1 3.1 2 1 0 2 2 2 0 ADP-ribosylation factor family VirE PF05272.11 OAG13671.1 - 0.049 13.4 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E NACHT PF05729.12 OAG13671.1 - 0.057 13.3 0.1 8.6 6.2 0.0 2.8 3 0 0 3 3 2 0 NACHT domain Ploopntkinase3 PF18751.1 OAG13671.1 - 0.077 12.9 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 EF-hand_8 PF13833.6 OAG13671.1 - 0.087 12.7 3.8 0.79 9.6 1.3 2.5 2 0 0 2 2 2 0 EF-hand domain pair G-alpha PF00503.20 OAG13671.1 - 0.09 11.9 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SPARC_Ca_bdg PF10591.9 OAG13671.1 - 0.12 12.7 0.1 37 4.7 0.0 2.8 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AIG1 PF04548.16 OAG13671.1 - 0.12 11.6 0.1 0.67 9.2 0.1 2.0 2 0 0 2 2 2 0 AIG1 family EF-hand_10 PF14788.6 OAG13671.1 - 0.14 12.1 0.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 EF hand AAA_28 PF13521.6 OAG13671.1 - 0.17 12.2 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG13671.1 - 0.17 12.0 0.0 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG13671.1 - 0.21 12.0 0.2 11 6.5 0.1 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zds_C PF08632.10 OAG13672.1 - 8.9e-29 99.0 1.2 1.5e-28 98.2 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Dynamin_M PF01031.20 OAG13674.1 - 2.3e-21 76.2 0.2 1.6e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 OAG13674.1 - 3.1e-18 66.4 0.0 9e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 OAG13674.1 - 0.00067 19.8 0.0 0.0042 17.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG13674.1 - 0.018 15.1 0.0 0.064 13.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Tim17 PF02466.19 OAG13675.1 - 7.6e-32 110.0 6.9 1.1e-31 109.5 6.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 OAG13675.1 - 0.091 12.9 6.0 0.15 12.2 0.6 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III SRP-alpha_N PF04086.13 OAG13676.1 - 1.5 8.7 15.0 0.099 12.6 10.0 1.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ACOX PF01756.19 OAG13677.1 - 2.2e-33 115.3 0.0 1.8e-32 112.4 0.0 2.1 1 1 1 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG13677.1 - 5.5e-18 65.7 0.0 1.3e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG13677.1 - 1.4e-07 31.6 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG13677.1 - 0.014 16.0 0.0 0.047 14.4 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG13677.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Oxidored_molyb PF00174.19 OAG13678.1 - 3.7e-49 166.6 0.0 6.1e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG13678.1 - 1.2e-17 64.2 3.0 2.8e-17 63.0 3.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Peptidase_S8 PF00082.22 OAG13679.1 - 1.9e-29 102.9 7.6 2.3e-29 102.6 7.6 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG13679.1 - 3.5e-06 27.6 0.0 7.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4286 PF14114.6 OAG13681.1 - 0.0031 18.0 0.3 0.0031 18.0 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4286) zf-C2H2 PF00096.26 OAG13682.1 - 0.32 11.5 9.5 0.41 11.2 3.9 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG13682.1 - 0.46 11.5 6.7 0.26 12.2 2.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF674 PF05056.12 OAG13682.1 - 0.55 9.0 2.2 2.3 7.0 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF674) FAD_binding_4 PF01565.23 OAG13683.1 - 2.9e-20 72.4 1.0 6.7e-20 71.2 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG13683.1 - 0.00012 22.1 0.4 0.00024 21.1 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like PAN_4 PF14295.6 OAG13685.1 - 0.0012 18.7 2.1 0.0029 17.5 2.1 1.6 1 0 0 1 1 1 1 PAN domain AIF_C PF14721.6 OAG13685.1 - 8.3 6.8 8.1 19 5.6 6.1 2.6 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Methyltransf_2 PF00891.18 OAG13686.1 - 3.5e-14 52.6 0.2 3.9e-13 49.2 0.0 2.2 2 1 0 2 2 2 1 O-methyltransferase domain B-block_TFIIIC PF04182.12 OAG13686.1 - 0.13 12.4 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Chromo_shadow PF01393.19 OAG13689.1 - 6.9e-18 64.5 1.8 3.1e-17 62.4 0.6 2.2 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 OAG13689.1 - 6.4e-11 42.0 0.3 1.9e-10 40.5 0.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cpn60_TCP1 PF00118.24 OAG13690.1 - 1.8e-159 531.5 5.6 2e-159 531.3 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 OAG13690.1 - 0.13 12.4 2.3 6.5 6.9 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain PAN_4 PF14295.6 OAG13692.1 - 0.38 10.7 5.0 0.24 11.4 3.0 1.6 2 0 0 2 2 2 0 PAN domain DUF3295 PF11702.8 OAG13693.1 - 2.1e-142 476.0 36.4 2.7e-142 475.6 36.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 OAG13693.1 - 3.2e-09 36.5 1.1 8.8e-09 35.1 1.0 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DNA_pol_phi PF04931.13 OAG13693.1 - 0.87 7.6 7.0 1.2 7.1 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 OAG13693.1 - 4 8.2 9.4 12 6.6 6.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 OAG13693.1 - 6.6 7.2 11.4 14 6.2 11.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fungal_trans PF04082.18 OAG13695.1 - 2.1e-13 49.9 0.2 3.8e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13695.1 - 4.3e-08 33.2 10.1 7.6e-08 32.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_processg_A PF02481.15 OAG13695.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF1287 PF06940.11 OAG13696.1 - 0.045 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Cutinase PF01083.22 OAG13697.1 - 9e-28 97.4 0.6 1.5e-27 96.7 0.6 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG13697.1 - 0.0006 19.4 0.1 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 PE-PPE domain MFS_1 PF07690.16 OAG13698.1 - 1.3e-17 63.8 53.7 8.2e-13 48.0 44.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG13698.1 - 1.5e-06 27.0 25.0 2e-06 26.5 25.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4969 PF16339.5 OAG13698.1 - 0.063 13.6 0.2 0.7 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) DUF4267 PF14087.6 OAG13698.1 - 0.58 10.2 8.2 1.9 8.6 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4267) Ctr PF04145.15 OAG13700.1 - 6.9e-36 124.1 2.5 8.4e-36 123.8 2.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3040 PF11239.8 OAG13700.1 - 0.61 10.4 4.0 0.32 11.3 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Oxidored_q3 PF00499.20 OAG13700.1 - 0.82 9.4 9.0 0.34 10.6 4.7 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LapA_dom PF06305.11 OAG13700.1 - 2 8.3 0.0 2 8.3 0.0 2.6 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ferric_reduct PF01794.19 OAG13701.1 - 1.2e-24 86.8 8.5 2.4e-24 85.9 8.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG13701.1 - 4.4e-19 69.1 0.0 6.6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG13701.1 - 4e-12 46.2 0.0 8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG13701.1 - 5.4e-05 23.8 0.0 0.00016 22.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Transgly_assoc PF04226.13 OAG13701.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.3 2 0 0 2 2 2 0 Transglycosylase associated protein F-box PF00646.33 OAG13702.1 - 2.1e-07 30.6 0.0 7.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG13702.1 - 1.4e-06 28.1 0.1 3.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 F-box-like Melibiase_2 PF16499.5 OAG13703.1 - 5.8e-48 163.5 0.4 1.2e-47 162.5 0.4 1.6 1 0 0 1 1 1 1 Alpha galactosidase A Mannosidase_ig PF17786.1 OAG13703.1 - 3.9e-18 65.8 0.1 1.5e-17 64.0 0.1 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Melibiase_C PF17801.1 OAG13703.1 - 8.7e-09 35.3 1.3 8.7e-09 35.3 1.3 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_2 PF00703.21 OAG13703.1 - 1.3e-08 35.5 0.0 3.5e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 OAG13703.1 - 4.3e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 OAG13703.1 - 4.5e-05 22.7 0.0 0.00015 20.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OAG13703.1 - 0.00037 20.4 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_3_C PF01915.22 OAG13704.1 - 2.4e-34 119.1 0.0 3.4e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG13704.1 - 3.4e-12 46.4 0.0 5.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG13704.1 - 0.0021 18.2 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Gpr1_Fun34_YaaH PF01184.19 OAG13705.1 - 2e-23 83.1 15.0 2.5e-23 82.8 15.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Meckelin PF09773.9 OAG13705.1 - 0.63 8.1 2.6 0.82 7.7 2.6 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) CDH-cyt PF16010.5 OAG13709.1 - 1e-55 188.3 0.1 1.8e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG13709.1 - 1.1e-32 113.6 0.0 1.6e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG13709.1 - 4.6e-18 66.1 2.1 1.2e-17 64.8 2.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 OAG13709.1 - 2.3e-13 49.9 6.1 6.1e-13 48.5 6.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 OAG13709.1 - 1.4e-07 31.0 3.3 0.00038 19.7 1.8 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG13709.1 - 2.6e-06 26.9 0.2 0.00091 18.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG13709.1 - 6.6e-05 22.7 2.1 0.075 12.6 1.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG13709.1 - 6.8e-05 21.7 1.6 0.00041 19.2 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG13709.1 - 0.0001 21.8 5.5 0.00081 18.8 2.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG13709.1 - 0.002 18.3 0.2 0.0061 16.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG13709.1 - 0.0024 17.2 1.9 0.5 9.6 1.5 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG13709.1 - 0.0026 16.9 0.4 0.02 14.0 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG13709.1 - 0.013 14.7 0.3 0.024 13.9 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAG13709.1 - 0.016 14.3 0.9 0.025 13.6 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG13709.1 - 0.033 14.7 2.0 2.6 8.7 0.4 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thiolase_C PF02803.18 OAG13710.1 - 3.6e-12 46.0 1.8 3.2e-11 43.0 0.6 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 OAG13710.1 - 4.2e-11 42.7 0.2 1.3e-08 34.5 0.1 3.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OAG13710.1 - 1.6e-06 27.9 0.1 0.00019 21.2 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG13710.1 - 0.0054 16.3 1.1 0.012 15.2 0.2 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OAG13710.1 - 0.032 12.9 0.3 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 OAG13710.1 - 0.062 13.3 0.4 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain FAD_binding_1 PF00667.20 OAG13711.1 - 1.2e-61 208.2 0.0 2.2e-61 207.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAG13711.1 - 2.8e-10 40.8 0.0 1.2e-09 38.8 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 OAG13711.1 - 3.8e-06 27.1 0.1 1.1e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 OAG13711.1 - 2.5e-05 24.4 0.1 0.00014 22.0 0.0 2.1 1 1 1 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 OAG13711.1 - 0.0017 18.2 0.1 0.0058 16.5 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 OAG13711.1 - 0.11 12.9 0.0 0.84 10.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF1653 PF07866.11 OAG13711.1 - 0.14 12.4 0.1 26 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1653) 7tm_3 PF00003.22 OAG13712.1 - 0.02 14.6 0.3 0.071 12.8 0.1 1.8 1 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Gpr1_Fun34_YaaH PF01184.19 OAG13713.1 - 1.2e-16 61.0 16.3 1.7e-16 60.5 16.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YfhO PF09586.10 OAG13713.1 - 0.12 10.6 1.1 0.15 10.3 1.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HIM1 PF08732.10 OAG13715.1 - 9.7e-10 38.2 0.0 2.3e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 OAG13715.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13715.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG13715.1 - 0.012 16.0 0.0 0.037 14.5 0.0 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OAG13715.1 - 0.022 14.0 0.0 2.3 7.3 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein NmrA PF05368.13 OAG13715.1 - 0.17 11.4 0.1 0.85 9.1 0.0 2.1 3 0 0 3 3 3 0 NmrA-like family MOSC PF03473.17 OAG13717.1 - 8.3e-23 80.8 0.0 1.9e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 OAG13717.1 - 4.7e-12 45.7 3.4 9e-12 44.8 3.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAG13717.1 - 9.1e-12 44.7 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain DUF2514 PF10721.9 OAG13719.1 - 0.13 12.3 5.3 0.16 12.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) 2-Hacid_dh_C PF02826.19 OAG13720.1 - 4.2e-57 192.4 0.1 1e-56 191.1 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG13720.1 - 3.4e-38 130.3 0.5 6.7e-38 129.4 0.5 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAG13720.1 - 0.0058 17.1 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 XdhC Rossmann domain LXG PF04740.12 OAG13720.1 - 0.068 12.9 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily Glyoxalase PF00903.25 OAG13721.1 - 5e-39 133.4 0.3 2.8e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG13721.1 - 3.8e-17 62.5 0.1 3.7e-07 30.4 0.0 3.8 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG13721.1 - 2.9e-07 31.2 0.0 0.026 15.3 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG13721.1 - 8.7e-07 29.2 0.0 0.029 14.5 0.0 2.5 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAG13721.1 - 5.5e-06 26.3 1.1 0.5 10.3 0.0 4.2 3 1 0 3 3 3 3 Glyoxalase-like domain DUF1338 PF07063.13 OAG13721.1 - 0.0028 16.9 0.0 1.2 8.2 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1338) MoaF PF10703.9 OAG13721.1 - 0.0059 16.5 0.1 0.47 10.4 0.0 2.4 2 0 0 2 2 2 1 MoaF N-terminal domain CppA_N PF14506.6 OAG13721.1 - 0.078 13.1 0.0 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal GCD14_N PF14801.6 OAG13721.1 - 0.12 12.2 0.0 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term FAD_binding_4 PF01565.23 OAG13723.1 - 6.8e-21 74.5 0.5 1.3e-20 73.5 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13723.1 - 0.00042 20.4 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PBP PF01161.20 OAG13724.1 - 2.7e-17 63.3 0.0 3.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2729 PF10870.8 OAG13726.1 - 0.099 12.5 0.6 0.22 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) 7TMR-HDED PF07697.11 OAG13727.1 - 0.17 12.0 3.1 0.3 11.2 3.1 1.3 1 0 0 1 1 1 0 7TM-HD extracellular LAMTOR PF15454.6 OAG13729.1 - 2.3e-13 50.5 0.4 4.9e-13 49.5 0.4 1.6 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ALS_ss_C PF10369.9 OAG13729.1 - 0.024 14.8 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Small subunit of acetolactate synthase SVIP PF15811.5 OAG13729.1 - 0.058 13.8 1.3 1.3 9.6 0.2 2.4 2 0 0 2 2 2 0 Small VCP/p97-interacting protein ABC_tran PF00005.27 OAG13731.1 - 1.3e-31 109.9 0.0 3.1e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAG13731.1 - 4.2e-26 92.2 6.8 7.4e-26 91.4 6.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAG13731.1 - 0.00012 21.6 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 OAG13731.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 OAG13731.1 - 0.0074 16.7 0.1 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG13731.1 - 0.067 13.5 0.3 0.26 11.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG13731.1 - 0.079 12.7 0.6 0.29 10.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG13731.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAG13731.1 - 0.2 11.4 1.4 1.1 9.1 0.6 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain p450 PF00067.22 OAG13732.1 - 6.3e-80 269.2 0.0 7.7e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 OAG13735.1 - 1.3e-24 86.5 1.7 2.9e-24 85.4 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13735.1 - 1.7e-11 44.1 0.1 3.3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1098 PF06497.11 OAG13735.1 - 0.079 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Tower PF09121.10 OAG13737.1 - 0.22 11.7 2.6 0.46 10.7 2.6 1.5 1 0 0 1 1 1 0 Tower Creatinase_N PF01321.18 OAG13738.1 - 0.022 15.4 0.0 0.023 15.3 0.0 1.0 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain VEGF_C PF14554.6 OAG13738.1 - 0.19 11.8 10.5 0.11 12.6 8.9 1.5 1 1 0 1 1 1 0 VEGF heparin-binding domain DUF3917 PF13055.6 OAG13739.1 - 0.16 12.4 0.3 0.37 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) HET PF06985.11 OAG13740.1 - 2e-13 50.9 6.5 1.8e-11 44.6 1.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.20 OAG13742.1 - 9.4e-58 196.1 0.0 6.9e-35 120.9 0.0 3.0 1 1 2 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family CsbD PF05532.12 OAG13743.1 - 4.5e-06 26.5 10.7 5.3e-05 23.0 1.0 2.1 2 0 0 2 2 2 2 CsbD-like adh_short PF00106.25 OAG13744.1 - 5.1e-35 120.7 2.1 6.4e-23 81.2 0.3 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13744.1 - 1.3e-31 110.0 3.1 1.3e-15 57.6 0.3 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 OAG13744.1 - 3.5e-23 81.4 4.3 1.4e-05 25.7 0.1 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13744.1 - 7.2e-14 51.9 0.3 0.085 13.2 0.0 5.8 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain KR PF08659.10 OAG13744.1 - 2.8e-13 50.2 0.3 1.1e-12 48.3 0.3 1.8 2 0 0 2 2 2 1 KR domain WD40_like PF17005.5 OAG13744.1 - 0.00032 20.1 0.1 5 6.4 0.0 4.1 4 1 1 5 5 5 2 WD40-like domain Polysacc_synt_2 PF02719.15 OAG13744.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ge1_WD40 PF16529.5 OAG13744.1 - 0.085 11.8 0.0 8.5 5.2 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_tran_WecB PF03808.13 OAG13744.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family tRNA_lig_CPD PF08302.11 OAG13745.1 - 4.4e-88 295.0 0.0 6.4e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 OAG13745.1 - 3.5e-85 285.3 0.2 6.4e-85 284.5 0.2 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 OAG13745.1 - 3.1e-51 173.8 0.7 1.5e-50 171.5 0.1 2.3 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_18 PF13238.6 OAG13745.1 - 0.019 15.5 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain HgmA PF04209.13 OAG13746.1 - 5.6e-166 552.5 0.1 6.5e-166 552.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Got1 PF04178.12 OAG13747.1 - 4.7e-35 120.4 15.4 6.3e-35 120.0 15.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 OAG13749.1 - 4.1e-12 45.9 0.0 2.4e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF676 PF05057.14 OAG13750.1 - 0.0013 18.3 0.1 0.0086 15.6 0.1 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAG13750.1 - 0.018 14.7 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG13750.1 - 0.036 14.7 0.2 0.044 14.4 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ubiquitin PF00240.23 OAG13751.1 - 4.9e-45 151.1 3.2 3.7e-24 84.3 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAG13751.1 - 1.8e-17 62.9 0.3 2.6e-09 36.8 0.1 3.4 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG13751.1 - 1.1e-10 41.8 0.5 0.00016 22.0 0.1 4.0 4 1 0 4 4 4 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG13751.1 - 1.4e-06 28.4 0.1 0.03 14.4 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG13751.1 - 9.2e-06 26.2 1.4 0.15 12.6 0.0 3.0 1 1 2 3 3 3 2 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 OAG13751.1 - 0.00012 21.9 0.2 0.0012 18.7 0.0 2.4 3 0 0 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG13751.1 - 0.0016 18.7 0.1 0.017 15.5 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain FERM_f0 PF16511.5 OAG13751.1 - 0.054 13.8 0.2 2.4 8.5 0.0 2.8 2 1 1 3 3 3 0 N-terminal or F0 domain of Talin-head FERM CHCH PF06747.13 OAG13752.1 - 6.3e-07 29.4 0.3 8.2e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 OAG13752.1 - 0.0012 19.1 1.4 0.0034 17.6 1.4 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 OAG13752.1 - 0.014 15.4 0.3 0.019 14.9 0.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 OAG13752.1 - 0.093 13.1 1.7 5 7.6 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) HET PF06985.11 OAG13753.1 - 1.6e-27 96.7 0.0 2.9e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1593 PF07632.11 OAG13754.1 - 1.1e-84 283.9 0.0 1.4e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ADH_N PF08240.12 OAG13755.1 - 7.4e-08 32.3 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG13755.1 - 3.2e-07 30.4 0.2 6.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG13755.1 - 0.0056 16.2 0.5 0.01 15.3 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase YjeF_N PF03853.15 OAG13755.1 - 0.063 13.2 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus MLANA PF14991.6 OAG13756.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Trp_oprn_chp PF09534.10 OAG13756.1 - 0.018 14.9 1.4 0.027 14.3 1.4 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sensor PF13796.6 OAG13756.1 - 0.055 13.5 0.2 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative sensor CD34_antigen PF06365.12 OAG13756.1 - 0.059 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Sulfate_transp PF00916.20 OAG13757.1 - 2.2e-63 214.3 16.5 3.8e-63 213.5 16.5 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 OAG13757.1 - 6.3e-15 55.0 0.0 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAG13757.1 - 3.4e-08 33.1 0.1 7.2e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 STAS domain Dicty_CAR PF05462.11 OAG13757.1 - 0.0017 17.6 1.5 0.0038 16.4 1.5 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF2530 PF10745.9 OAG13757.1 - 3 8.1 6.4 9.9 6.5 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DAGK_cat PF00781.24 OAG13759.1 - 2.6e-24 85.2 0.1 4.1e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain S-AdoMet_synt_M PF02772.16 OAG13759.1 - 0.025 14.8 0.0 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain PliI PF16743.5 OAG13759.1 - 0.08 12.7 0.0 19 5.0 0.0 2.7 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme Adaptin_N PF01602.20 OAG13760.1 - 4.5e-90 302.7 3.0 8.1e-90 301.8 3.0 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OAG13760.1 - 4.3e-58 195.2 1.3 1e-57 194.0 1.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OAG13760.1 - 9.2e-57 190.5 0.0 2.5e-56 189.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 OAG13760.1 - 7.1e-10 39.2 6.9 2.7e-09 37.3 0.0 3.7 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG13760.1 - 3e-07 30.7 3.9 0.00097 19.5 0.0 4.8 3 2 2 5 5 5 3 HEAT repeats Coatomer_g_Cpla PF16381.5 OAG13760.1 - 8.8e-05 22.6 0.1 0.00049 20.2 0.0 2.3 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 OAG13760.1 - 0.014 15.6 1.1 1.7 9.1 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat AP4E_app_platf PF14807.6 OAG13760.1 - 0.019 15.3 0.3 0.067 13.6 0.3 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 OAG13760.1 - 0.13 12.8 0.4 3 8.5 0.0 3.5 2 1 1 3 3 3 0 HEAT-like repeat Mago_nashi PF02792.14 OAG13761.1 - 3.9e-73 244.2 0.1 4.4e-73 244.1 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 OAG13762.1 - 4.1e-68 228.3 1.2 5e-68 228.0 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Methyltransf_4 PF02390.17 OAG13763.1 - 8.3e-50 168.6 0.3 2.9e-49 166.9 0.0 2.0 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 OAG13763.1 - 1.4e-05 25.7 0.0 6.8e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG13763.1 - 3.2e-05 24.6 0.0 9.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG13763.1 - 0.00019 21.0 0.0 0.00095 18.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OAG13763.1 - 0.00086 19.1 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG13763.1 - 0.0029 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAG13763.1 - 0.0042 17.1 0.0 0.0095 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG13763.1 - 0.0046 17.6 0.0 0.042 14.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG13763.1 - 0.053 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HA2 PF04408.23 OAG13763.1 - 0.21 11.9 0.3 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 Helicase associated domain (HA2) Zn_ribbon_recom PF13408.6 OAG13764.1 - 0.057 13.9 0.8 0.11 13.1 0.1 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF465 PF04325.13 OAG13765.1 - 0.063 13.3 0.7 0.58 10.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) REF PF05755.12 OAG13765.1 - 0.13 12.0 3.5 0.34 10.7 3.5 1.6 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Bac_rhamnosid_C PF17390.2 OAG13765.1 - 0.15 11.8 0.0 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain F-box-like PF12937.7 OAG13766.1 - 4.6e-08 32.8 0.2 3.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG13766.1 - 0.17 11.8 6.9 0.039 13.8 1.4 2.9 2 1 0 2 2 2 0 F-box domain Glyco_hydro_16 PF00722.21 OAG13767.1 - 2.6e-08 33.6 3.2 3.7e-08 33.1 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GDPD PF03009.17 OAG13769.1 - 3.4e-74 249.9 0.0 7.6e-74 248.7 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 OAG13769.1 - 1.5e-26 92.8 0.2 1.1e-09 38.7 0.1 4.3 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG13769.1 - 1.2e-22 80.0 0.9 7e-08 32.9 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 OAG13769.1 - 1.4e-18 68.0 20.8 8e-12 45.8 0.1 4.5 2 2 2 4 4 4 3 SPX domain Ank_5 PF13857.6 OAG13769.1 - 1.1e-17 63.8 0.1 2.2e-07 31.0 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG13769.1 - 4.8e-14 52.1 2.1 0.041 14.3 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OAG13769.1 - 2.5e-13 48.9 2.0 0.31 11.7 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat XAP5 PF04921.14 OAG13770.1 - 2e-84 283.3 0.1 2.7e-84 282.9 0.1 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 OAG13770.1 - 0.015 15.8 1.4 0.015 15.8 1.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) DUF4169 PF13770.6 OAG13770.1 - 2.1 8.7 6.1 0.73 10.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) UBA PF00627.31 OAG13771.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Chitin_bind_1 PF00187.19 OAG13773.1 - 4.3e-30 103.9 115.0 2.7e-09 37.3 14.2 5.8 5 0 0 5 5 5 4 Chitin recognition protein Polysacc_deac_1 PF01522.21 OAG13773.1 - 1e-27 96.5 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAG13773.1 - 0.0053 16.0 0.0 0.0078 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 UQ_con PF00179.26 OAG13774.1 - 1.2e-32 112.4 0.0 2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG13774.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF3439 PF11921.8 OAG13774.1 - 8.6 6.4 8.3 15 5.5 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nup160 PF11715.8 OAG13775.1 - 6.6e-127 424.4 0.3 8.7e-127 424.0 0.3 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Aldo_ket_red PF00248.21 OAG13776.1 - 5.1e-48 163.8 0.0 2.6e-46 158.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.9 OAG13777.1 - 4.9e-24 84.7 16.3 4.9e-24 84.7 16.3 2.2 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 OAG13777.1 - 0.28 10.7 17.5 0.38 10.3 17.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MFS_1 PF07690.16 OAG13778.1 - 8.8e-25 87.4 53.8 3.1e-15 56.0 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 OAG13779.1 - 8.5e-19 67.7 0.2 1.3e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13779.1 - 0.018 15.2 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like MAP1B_neuraxin PF00414.17 OAG13779.1 - 0.083 12.5 1.7 0.17 11.5 1.7 1.5 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat Monellin PF09200.10 OAG13781.1 - 0.02 14.7 0.2 0.04 13.8 0.2 1.5 1 0 0 1 1 1 0 Monellin zf-C2H2_4 PF13894.6 OAG13781.1 - 0.058 14.3 12.1 0.6 11.1 5.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger K1377 PF15352.6 OAG13781.1 - 0.092 11.0 0.0 0.17 10.1 0.0 1.3 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy zf-C2H2 PF00096.26 OAG13781.1 - 0.22 12.0 13.0 1.3 9.7 5.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADH_N PF08240.12 OAG13782.1 - 5.2e-10 39.2 0.8 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG13782.1 - 9.2e-08 32.1 0.1 2.4e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SKI PF01202.22 OAG13783.1 - 1.3e-12 48.1 0.0 1.8e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAG13783.1 - 6.6e-10 39.6 0.0 1.2e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG13783.1 - 2.1e-08 34.4 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG13783.1 - 1.1e-07 32.3 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAG13783.1 - 1.9e-07 31.2 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 OAG13783.1 - 3.5e-06 26.9 0.0 7e-06 25.9 0.0 1.5 1 1 1 2 2 2 1 Cytidylate kinase dNK PF01712.19 OAG13783.1 - 7e-06 26.0 0.1 0.0096 15.8 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 OAG13783.1 - 9.6e-05 22.7 0.0 0.00023 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG13783.1 - 0.00025 21.5 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OAG13783.1 - 0.00095 19.4 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 OAG13783.1 - 0.0035 17.4 0.0 0.0053 16.9 0.0 1.6 1 1 0 1 1 1 1 tRNA ligase kinase domain Mg_chelatase PF01078.21 OAG13783.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG13783.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAG13783.1 - 0.0079 16.7 0.0 0.01 16.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 OAG13783.1 - 0.0087 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase CoaE PF01121.20 OAG13783.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.5 2 0 0 2 2 1 1 Dephospho-CoA kinase AAA_14 PF13173.6 OAG13783.1 - 0.0096 16.0 0.0 0.026 14.5 0.0 1.8 2 1 0 2 2 1 1 AAA domain Ploopntkinase1 PF18748.1 OAG13783.1 - 0.011 15.3 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 APS_kinase PF01583.20 OAG13783.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 OAG13783.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OAG13783.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG13783.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAG13783.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG13783.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Cytidylate_kin2 PF13189.6 OAG13783.1 - 0.021 14.9 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family PRK PF00485.18 OAG13783.1 - 0.024 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 OAG13783.1 - 0.032 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OAG13783.1 - 0.034 13.2 1.0 0.085 11.9 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OAG13783.1 - 0.042 13.1 0.2 0.21 10.8 0.2 1.9 1 1 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 OAG13783.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OAG13783.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 OAG13783.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 OAG13783.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 OAG13783.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 OAG13783.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAG13783.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAG13783.1 - 0.13 12.2 0.1 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 OAG13783.1 - 0.15 11.7 0.2 4 7.1 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase Sigma54_activ_2 PF14532.6 OAG13783.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain SMC_N PF02463.19 OAG13783.1 - 0.16 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Vps26 PF03643.15 OAG13784.1 - 9.1e-129 428.3 0.7 1.1e-128 428.1 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OAG13784.1 - 0.00076 19.6 1.3 0.44 10.6 0.1 3.4 1 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 OAG13784.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D MIP PF00230.20 OAG13785.1 - 1.1e-35 123.4 8.3 1.5e-35 122.9 8.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1340 PF07067.11 OAG13785.1 - 0.053 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) SLAC1 PF03595.17 OAG13786.1 - 5.3e-69 233.0 45.9 5.9e-69 232.8 45.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1242 PF06842.12 OAG13786.1 - 0.0062 16.3 0.3 0.033 14.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) F-box-like PF12937.7 OAG13787.1 - 0.00016 21.5 0.2 0.00036 20.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 OAG13788.1 - 0.00014 21.7 0.9 0.024 14.5 0.0 3.6 3 0 0 3 3 3 1 F-box-like CN_hydrolase PF00795.22 OAG13790.1 - 2.2e-49 168.1 0.0 2.5e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TMF_TATA_bd PF12325.8 OAG13791.1 - 2.4e-38 130.9 10.3 2.4e-38 130.9 10.3 6.5 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAG13791.1 - 1.6e-21 76.0 12.7 1.6e-21 76.0 12.7 8.4 6 3 4 10 10 10 1 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 OAG13791.1 - 0.0011 19.1 1.5 0.0011 19.1 1.5 5.1 2 1 2 4 4 4 2 Uncharacterised protein family (UPF0242) N-terminus Mating_N PF12731.7 OAG13791.1 - 0.0034 17.4 1.1 0.092 12.8 0.0 3.4 3 0 0 3 3 3 1 Mating-type protein beta 1 DUF1664 PF07889.12 OAG13791.1 - 0.021 14.8 1.2 0.021 14.8 1.2 6.7 2 2 6 8 8 8 0 Protein of unknown function (DUF1664) WD40_alt PF14077.6 OAG13791.1 - 0.045 13.6 4.8 0.053 13.4 0.8 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif DASH_Dam1 PF08653.10 OAG13791.1 - 0.21 11.4 4.4 4.4 7.2 0.1 4.2 3 1 1 4 4 4 0 DASH complex subunit Dam1 HET PF06985.11 OAG13792.1 - 2.6e-07 31.1 11.1 2.8e-05 24.5 5.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 OAG13794.1 - 9.5e-62 205.0 3.3 1.3e-20 73.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.14 OAG13795.1 - 1.7e-31 109.5 0.0 3.2e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 MT-A70 Metallophos PF00149.28 OAG13802.1 - 1.5e-33 117.1 0.0 6.9e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAG13802.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 OAG13802.1 - 0.13 12.5 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain HET PF06985.11 OAG13803.1 - 0.00053 20.4 4.2 0.59 10.5 0.2 3.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FeoB_N PF02421.18 OAG13804.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF866 PF05907.13 OAG13805.1 - 1.1e-66 223.5 0.1 1.3e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.29 OAG13805.1 - 0.039 13.8 0.5 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 PHD-finger DUF4379 PF14311.6 OAG13805.1 - 0.12 12.8 1.3 0.12 12.8 1.3 1.9 1 1 0 1 1 1 0 Probable Zinc-ribbon domain HalOD2 PF18547.1 OAG13805.1 - 0.12 12.3 0.4 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 RNHCP PF12647.7 OAG13805.1 - 0.22 11.5 2.2 2.4 8.2 0.3 2.2 1 1 1 2 2 2 0 RNHCP domain T4_baseplate PF12322.8 OAG13805.1 - 0.23 10.9 0.8 4.7 6.6 0.0 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Zn_ribbon_SprT PF17283.2 OAG13805.1 - 0.29 11.1 5.9 1.6 8.7 5.9 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain FAD_binding_4 PF01565.23 OAG13806.1 - 4.3e-23 81.6 0.7 8.9e-23 80.6 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain RTP1_C1 PF10363.9 OAG13807.1 - 2.3e-24 85.7 0.0 1.8e-22 79.6 0.0 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 OAG13807.1 - 1e-09 37.8 0.6 2.3e-09 36.8 0.6 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 LSM PF01423.22 OAG13808.1 - 2.7e-18 65.4 0.2 3.1e-18 65.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain PPR_long PF17177.4 OAG13809.1 - 0.00079 18.9 0.0 0.29 10.4 0.0 2.7 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 OAG13809.1 - 0.0027 17.9 0.1 5.2 7.3 0.0 3.7 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 OAG13809.1 - 0.0038 17.3 0.0 5.3 7.2 0.0 3.8 2 1 2 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.20 OAG13809.1 - 0.0067 16.6 0.2 2.4 8.6 0.1 4.0 4 0 0 4 4 4 1 PPR repeat TFIIE_beta PF02186.15 OAG13809.1 - 0.17 12.2 0.3 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 TFIIE beta subunit core domain HYR PF02494.16 OAG13810.1 - 0.00072 19.8 1.0 7.8 6.9 0.1 4.2 1 1 3 4 4 4 3 HYR domain I-set PF07679.16 OAG13810.1 - 0.36 10.9 14.9 15 5.7 1.2 5.1 1 1 3 4 4 4 0 Immunoglobulin I-set domain Adipokin_hormo PF06377.11 OAG13810.1 - 2.5 8.5 7.1 5.7 7.4 0.6 3.5 4 1 0 4 4 4 0 Adipokinetic hormone Cullin_Nedd8 PF10557.9 OAG13811.1 - 0.052 13.6 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain DUF2721 PF11026.8 OAG13812.1 - 2.3e-05 24.3 0.5 0.36 10.7 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2721) DUF1656 PF07869.12 OAG13812.1 - 0.037 14.0 0.8 0.037 14.0 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) YrhK PF14145.6 OAG13812.1 - 0.051 13.4 16.7 0.038 13.9 2.8 4.2 3 1 0 3 3 3 0 YrhK-like protein DUF4231 PF14015.6 OAG13812.1 - 0.97 9.9 5.1 18 5.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) FAD_binding_4 PF01565.23 OAG13813.1 - 1.5e-21 76.6 0.7 3.1e-21 75.6 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG13813.1 - 7e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ROQ_II PF18386.1 OAG13813.1 - 0.1 12.4 0.1 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Roquin II domain Glyco_hydro_17 PF00332.18 OAG13814.1 - 0.00054 19.6 0.4 0.0011 18.6 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Herpes_UL4 PF03277.13 OAG13815.1 - 0.075 12.6 1.4 0.091 12.4 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family zf-C4pol PF14260.6 OAG13817.1 - 0.7 10.4 5.3 8.2 7.0 5.3 2.6 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta FmiP_Thoc5 PF09766.9 OAG13818.1 - 2e-20 73.4 14.5 2e-20 73.4 14.5 1.8 2 1 0 2 2 2 1 Fms-interacting protein/Thoc5 DUF349 PF03993.12 OAG13818.1 - 0.038 14.3 3.0 0.038 14.3 3.0 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) HALZ PF02183.18 OAG13818.1 - 0.051 13.8 9.2 2 8.7 0.3 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper SNF2_N PF00176.23 OAG13819.1 - 1.2e-59 201.8 0.0 2.1e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 OAG13819.1 - 3.7e-10 39.5 8.6 1.1e-09 37.9 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG13819.1 - 2.7e-08 33.5 6.8 5.8e-08 32.5 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG13819.1 - 3.7e-08 33.1 9.4 1e-07 31.7 9.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG13819.1 - 8.3e-08 32.5 10.3 2.1e-07 31.2 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAG13819.1 - 9.5e-06 25.4 7.2 2.3e-05 24.2 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG13819.1 - 4e-05 23.5 7.8 0.00011 22.1 7.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG13819.1 - 5.1e-05 23.2 4.8 0.00012 22.0 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG13819.1 - 6.6e-05 23.1 8.4 0.0002 21.6 8.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAG13819.1 - 0.00047 20.3 7.7 0.0011 19.1 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.31 OAG13819.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-ANAPC11 PF12861.7 OAG13819.1 - 0.024 14.7 3.1 0.051 13.6 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 OAG13819.1 - 0.039 14.1 3.7 0.094 12.9 3.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 OAG13819.1 - 0.051 13.5 2.1 0.11 12.5 2.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF16 PF01519.16 OAG13819.1 - 0.094 13.2 0.8 0.29 11.6 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 MGC-24 PF05283.11 OAG13820.1 - 4.9e-05 23.8 2.9 4.9e-05 23.8 2.9 2.8 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sod_Fe_C PF02777.18 OAG13821.1 - 6.3e-19 68.0 0.0 2e-16 60.0 0.0 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain PLAC8 PF04749.17 OAG13823.1 - 3.9e-12 47.0 11.8 7.1e-12 46.2 11.8 1.4 1 0 0 1 1 1 1 PLAC8 family DEAD PF00270.29 OAG13824.1 - 3.7e-48 163.6 0.0 1.6e-47 161.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG13824.1 - 1.4e-32 112.3 0.0 2.9e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG13824.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG13824.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Pro_isomerase PF00160.21 OAG13825.1 - 8.9e-50 169.0 0.3 1.1e-49 168.8 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 OAG13826.1 - 6.3e-19 68.6 1.1 5e-17 62.5 1.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 RhoGAP PF00620.27 OAG13827.1 - 1.6e-41 141.7 0.0 2.9e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAG13827.1 - 1.3e-13 51.3 0.0 3.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAG13827.1 - 9.5e-06 26.0 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OAG13827.1 - 0.02 15.2 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain An_peroxidase PF03098.15 OAG13829.1 - 4.5e-39 134.4 0.0 6.7e-25 87.7 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAG13829.1 - 6.2e-09 35.1 0.3 6.8e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 PP_kinase_N PF13089.6 OAG13829.1 - 0.2 12.0 0.1 0.45 10.9 0.1 1.5 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain DUF2235 PF09994.9 OAG13830.1 - 1e-101 340.1 0.7 1.4e-101 339.6 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3140 PF11338.8 OAG13831.1 - 2.9e-31 107.8 2.9 3.3e-31 107.6 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Sugar_tr PF00083.24 OAG13832.1 - 3.2e-129 431.7 20.0 3.6e-129 431.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13832.1 - 4e-24 85.2 40.4 1.5e-17 63.5 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG13832.1 - 0.31 10.8 2.8 0.32 10.8 0.1 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gly-zipper_YMGG PF13441.6 OAG13832.1 - 2.7 7.8 7.0 0.52 10.1 1.0 3.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper Peptidase_M50B PF13398.6 OAG13833.1 - 9.3e-60 201.7 18.6 1.2e-59 201.3 18.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF2157 PF09925.9 OAG13833.1 - 0.047 13.5 9.0 0.13 12.0 1.8 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Patched PF02460.18 OAG13833.1 - 0.1 10.6 6.3 0.17 9.9 6.3 1.2 1 0 0 1 1 1 0 Patched family YlaC PF10777.9 OAG13833.1 - 3.9 7.3 5.7 0.28 11.0 0.3 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC Atg14 PF10186.9 OAG13834.1 - 0.057 12.5 10.4 0.077 12.1 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ThiF PF00899.21 OAG13834.1 - 0.16 11.3 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 ThiF family SPATA24 PF15175.6 OAG13834.1 - 0.2 11.6 11.7 0.027 14.4 6.5 1.9 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 FUSC PF04632.12 OAG13834.1 - 0.94 7.9 8.2 1.1 7.7 8.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 OAG13834.1 - 4.4 8.0 17.5 0.75 10.4 4.1 3.1 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2564 PF10819.8 OAG13834.1 - 8 6.9 11.3 0.59 10.6 3.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) FMN_dh PF01070.18 OAG13835.1 - 8.8e-113 376.9 0.0 1e-112 376.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 OAG13835.1 - 0.00011 21.6 0.1 0.054 12.8 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG13835.1 - 0.00031 19.9 0.7 0.00072 18.6 0.4 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG13835.1 - 0.00031 20.0 0.2 0.0005 19.3 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG13835.1 - 0.0012 18.3 0.3 0.002 17.6 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG13835.1 - 0.05 13.0 0.3 1.6 8.1 0.0 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 OAG13835.1 - 0.15 11.2 0.0 0.36 10.0 0.0 1.6 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase adh_short_C2 PF13561.6 OAG13836.1 - 7.3e-49 166.4 0.1 9.8e-49 166.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13836.1 - 9.6e-36 123.1 0.1 1.2e-35 122.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG13836.1 - 9e-05 22.5 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OAG13836.1 - 0.04 14.4 0.1 0.066 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAG13836.1 - 0.083 12.8 0.2 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Esterase PF00756.20 OAG13837.1 - 2.7e-10 40.3 0.0 5.2e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAG13837.1 - 7.1e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG13837.1 - 0.0023 17.2 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 OAG13838.1 - 3.9e-81 273.5 0.1 2.8e-72 244.3 0.2 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG13838.1 - 8.1e-13 48.7 0.2 1.8e-12 47.6 0.2 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG13838.1 - 0.024 14.1 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG13838.1 - 0.046 14.3 7.3 0.088 13.4 7.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Phage_holin_2_2 PF10746.9 OAG13839.1 - 0.58 9.9 4.4 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Phage holin T7 family, holin superfamily II HeLo PF14479.6 OAG13840.1 - 5.2e-35 121.2 0.0 1.1e-34 120.2 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation T6SS-SciN PF12790.7 OAG13840.1 - 0.0051 16.5 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 SR-25 PF10500.9 OAG13841.1 - 4 7.0 19.3 5.4 6.6 4.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein E1-E2_ATPase PF00122.20 OAG13842.1 - 1.1e-51 174.9 6.5 2.7e-51 173.7 1.2 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG13842.1 - 1.1e-44 152.4 3.4 1.1e-44 152.4 3.4 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAG13842.1 - 1.9e-22 79.2 0.0 3.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG13842.1 - 1.9e-22 80.6 0.9 3.5e-21 76.5 0.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG13842.1 - 2.7e-19 68.6 0.1 9.2e-19 66.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG13842.1 - 3.8e-09 36.7 0.4 1.9e-06 27.8 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG13842.1 - 1.5e-06 28.8 0.0 3.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Response_reg PF00072.24 OAG13843.1 - 6.2e-21 74.7 0.1 3.7e-20 72.1 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 OAG13843.1 - 1.2e-19 70.9 0.0 3.1e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG13843.1 - 6.1e-06 26.2 0.1 1.7e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF5462 PF17547.2 OAG13843.1 - 0.0058 16.0 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5462) Apolipoprotein PF01442.18 OAG13843.1 - 0.14 12.1 1.5 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Enolase_C PF00113.22 OAG13844.1 - 5.8e-154 511.6 0.1 7.8e-154 511.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAG13844.1 - 1e-57 193.9 0.5 2e-57 193.0 0.5 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAG13844.1 - 3.1e-06 26.9 0.0 5.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG13844.1 - 0.049 12.8 1.5 1.2 8.2 0.2 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Methyltransf_3 PF01596.17 OAG13844.1 - 0.07 12.3 0.3 0.13 11.4 0.3 1.4 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.26 OAG13845.1 - 9.6e-37 126.3 0.0 1.1e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DHQ_synthase PF01761.20 OAG13846.1 - 7.9e-54 182.6 0.0 1.1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAG13846.1 - 5.5e-10 39.4 0.0 8.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 OAG13847.1 - 4e-11 42.5 0.0 5.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG13847.1 - 1.3e-10 42.2 0.0 2.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 OAG13847.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase Parvo_coat PF00740.18 OAG13848.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DSBA PF01323.20 OAG13850.1 - 2.7e-19 69.7 0.0 3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Dpy-30 PF05186.13 OAG13850.1 - 0.095 12.4 0.2 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Dpy-30 motif WD40 PF00400.32 OAG13851.1 - 1.4e-54 180.8 25.0 3.1e-06 27.8 0.0 12.6 12 1 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 OAG13851.1 - 4.4e-49 166.0 0.1 7e-49 165.4 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OAG13851.1 - 3.9e-19 68.7 3.8 0.013 15.8 0.0 9.2 5 3 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG13851.1 - 0.00018 20.3 3.9 0.3 9.7 0.0 4.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG13851.1 - 0.00025 20.1 0.6 4 6.3 0.0 5.1 6 1 0 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAG13851.1 - 0.00063 18.6 0.5 10 4.7 0.1 4.6 3 1 1 5 5 5 2 Nup133 N terminal like PALB2_WD40 PF16756.5 OAG13851.1 - 0.0017 17.4 0.2 1.4 7.8 0.1 2.4 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 OAG13851.1 - 0.2 11.0 0.0 17 4.6 0.0 3.4 3 1 1 4 4 4 0 WD40-like domain Kinesin PF00225.23 OAG13854.1 - 2.3e-93 312.8 0.0 4.3e-93 311.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG13854.1 - 7.9e-23 81.0 0.0 1.6e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 OAG13854.1 - 0.016 15.0 1.6 0.08 12.8 0.3 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Anti-adapt_IraP PF10796.9 OAG13854.1 - 0.041 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF4241 PF14025.6 OAG13854.1 - 0.056 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) FapA PF03961.13 OAG13854.1 - 0.73 8.4 10.0 0.034 12.8 2.4 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OAG13854.1 - 5.1 6.4 13.6 4.5 6.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFB6 PF17110.5 OAG13854.1 - 6.9 6.4 6.2 3.5 7.3 3.4 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH UCH PF00443.29 OAG13857.1 - 9.7e-29 100.6 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG13857.1 - 1e-10 41.8 0.2 1.9e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAG13857.1 - 0.022 14.3 0.3 0.33 10.5 0.3 2.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HCNGP PF07818.13 OAG13857.1 - 0.12 13.0 0.0 0.36 11.5 0.0 1.8 1 0 0 1 1 1 0 HCNGP-like protein Cpn60_TCP1 PF00118.24 OAG13858.1 - 3.2e-143 477.9 11.8 3.6e-143 477.7 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAG13858.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Ribonuc_2-5A PF06479.12 OAG13859.1 - 2.5e-43 147.3 1.3 2.6e-43 147.2 0.2 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 OAG13859.1 - 5.3e-41 140.7 0.0 1.9e-40 138.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13859.1 - 1.4e-19 70.4 0.0 2.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG13859.1 - 0.00027 19.8 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PQQ PF01011.21 OAG13859.1 - 0.0046 16.8 0.2 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat APH PF01636.23 OAG13859.1 - 0.016 15.1 0.3 0.087 12.7 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG13859.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polyketide_cyc PF03364.20 OAG13860.1 - 7.6e-22 77.9 0.0 1.3e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAG13860.1 - 1.1e-06 29.0 0.0 1.2e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.12 OAG13861.1 - 1.9e-14 54.2 0.0 5.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG13861.1 - 9.6e-13 48.7 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG13861.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG13861.1 - 2e-10 41.2 0.0 4.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG13861.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG13861.1 - 3.1e-05 23.4 0.0 6.7e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 OAG13861.1 - 0.0007 20.6 0.0 0.0015 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAG13861.1 - 0.043 13.0 0.0 0.98 8.5 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF3419 PF11899.8 OAG13861.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) MTS PF05175.14 OAG13861.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_22 PF13401.6 OAG13862.1 - 1.2e-10 41.7 0.1 4.8e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG13862.1 - 8.5e-10 39.3 0.1 7.6e-09 36.2 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG13862.1 - 1.6e-09 38.3 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 OAG13862.1 - 2.3e-09 37.1 0.0 6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 OAG13862.1 - 1.5e-05 25.1 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 OAG13862.1 - 0.00023 21.5 0.0 0.00068 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 OAG13862.1 - 0.00061 19.2 0.0 0.002 17.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OAG13862.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG13862.1 - 0.0081 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 OAG13862.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 OAG13862.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 OAG13862.1 - 0.022 14.6 0.1 0.92 9.4 0.0 2.9 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAG13862.1 - 0.028 14.4 0.0 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG13862.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Cu_amine_oxid PF01179.20 OAG13865.1 - 2.9e-118 395.4 1.8 3.8e-118 395.0 1.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG13865.1 - 6.2e-27 93.2 0.8 2.6e-26 91.2 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG13865.1 - 0.00047 20.3 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Helo_like_N PF17111.5 OAG13866.1 - 0.018 14.4 0.3 0.03 13.7 0.3 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Sugar_tr PF00083.24 OAG13867.1 - 1.2e-40 139.8 14.8 2.3e-27 96.0 4.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG13867.1 - 3.1e-21 75.7 20.3 3.3e-21 75.6 18.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Ric8 PF10165.9 OAG13867.1 - 0.14 11.2 0.5 3.3 6.6 0.1 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn AA_permease PF00324.21 OAG13868.1 - 1.8e-107 359.9 36.9 2.2e-107 359.6 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG13868.1 - 2.9e-25 89.0 41.7 3.4e-25 88.7 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease LRR_8 PF13855.6 OAG13869.1 - 2.3e-06 27.3 2.3 4.5e-06 26.3 2.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAG13869.1 - 0.0018 18.6 0.7 0.0048 17.3 0.7 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) UL42 PF17638.2 OAG13869.1 - 4.1 7.4 7.5 0.5 10.3 0.4 2.4 2 0 0 2 2 2 0 HCMV UL42 NAD_binding_10 PF13460.6 OAG13870.1 - 4.3e-05 23.5 0.0 5.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13870.1 - 0.0078 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG13870.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 OAG13870.1 - 0.043 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 OAG13870.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 OAG13870.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ABC_tran PF00005.27 OAG13874.1 - 7.1e-46 156.1 0.1 1.7e-23 83.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OAG13874.1 - 3.3e-27 95.5 42.3 1.4e-16 60.6 24.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAG13874.1 - 2e-24 86.9 5.0 3.6e-06 27.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG13874.1 - 1.1e-08 34.8 4.3 0.021 14.3 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG13874.1 - 3.1e-08 33.3 1.1 8.5e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG13874.1 - 4.7e-06 27.3 3.6 0.018 15.5 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 OAG13874.1 - 1.2e-05 25.3 0.0 0.035 13.8 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG13874.1 - 2.5e-05 24.3 0.5 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 OAG13874.1 - 0.00062 19.4 0.2 0.31 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG13874.1 - 0.0038 17.6 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OAG13874.1 - 0.011 15.4 0.4 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG13874.1 - 0.017 15.4 0.1 0.86 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 OAG13874.1 - 0.069 13.9 0.0 13 6.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 OAG13874.1 - 0.15 11.4 0.6 3.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 OAG13874.1 - 0.35 11.1 1.0 5.2 7.3 0.4 2.4 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 OAG13875.1 - 7.1e-12 45.6 0.0 9.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG13875.1 - 2.2e-08 34.1 0.0 3.6e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG13875.1 - 2.4e-08 33.8 0.0 4.5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG13875.1 - 1.1e-06 29.0 0.0 1.5e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG13875.1 - 0.0048 17.0 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAG13875.1 - 0.01 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 OAG13876.1 - 4.1e-14 52.4 0.0 5.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG13876.1 - 0.054 14.2 0.0 0.087 13.6 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Pyr_redox_2 PF07992.14 OAG13877.1 - 9.5e-15 54.6 0.0 1.8e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13877.1 - 6.3e-12 45.5 2.2 9.7e-10 38.5 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG13877.1 - 1.7e-09 37.4 0.0 1.6e-08 34.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG13877.1 - 3e-08 32.5 0.0 4.3e-06 25.4 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 OAG13877.1 - 3.3e-07 30.2 2.9 9.3e-05 22.2 1.0 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG13877.1 - 5.4e-07 29.3 0.2 2.8e-06 26.9 0.2 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG13877.1 - 3.5e-06 26.5 1.4 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG13877.1 - 3.8e-06 27.4 0.7 0.011 16.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG13877.1 - 3.6e-05 23.0 6.8 0.024 13.7 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG13877.1 - 4.8e-05 22.9 7.7 0.00013 21.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG13877.1 - 6.7e-05 22.2 0.1 0.00024 20.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG13877.1 - 7.9e-05 21.5 0.3 7.9e-05 21.5 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAG13877.1 - 0.00014 21.2 0.1 0.00014 21.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAG13877.1 - 0.0012 18.1 1.4 0.0018 17.5 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAG13877.1 - 0.0013 18.7 1.0 0.0061 16.6 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG13877.1 - 0.0065 15.6 1.2 0.0065 15.6 1.2 2.3 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 OAG13877.1 - 0.73 8.6 5.2 1.6 7.4 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 OAG13877.1 - 0.74 9.7 2.0 21 5.0 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain STI1 PF17830.1 OAG13878.1 - 0.22 11.5 17.7 0.35 10.8 0.7 5.4 5 2 0 5 5 5 0 STI1 domain ParE-like_toxin PF15781.5 OAG13878.1 - 0.34 10.9 2.7 7.7 6.6 0.0 3.2 3 0 0 3 3 3 0 ParE-like toxin of type II bacterial toxin-antitoxin system DUF3276 PF11680.8 OAG13878.1 - 6 7.0 7.9 0.52 10.5 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3276) MLANA PF14991.6 OAG13879.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Gram_pos_anchor PF00746.21 OAG13879.1 - 0.038 13.9 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CEND1 PF15677.5 OAG13879.1 - 0.11 13.0 1.2 5.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 Acetyltransf_10 PF13673.7 OAG13881.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG13881.1 - 2.1e-05 24.9 0.0 4.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG13881.1 - 0.00017 21.8 0.0 0.00027 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4411 PF14367.6 OAG13881.1 - 0.035 14.0 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) FR47 PF08445.10 OAG13881.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.3 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 OAG13881.1 - 0.14 12.2 0.0 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cutinase PF01083.22 OAG13882.1 - 3.2e-45 154.2 1.5 4.3e-45 153.8 1.5 1.2 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.20 OAG13882.1 - 0.002 18.3 0.1 0.0027 17.9 0.1 1.1 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 OAG13882.1 - 0.023 14.2 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_4 PF12146.8 OAG13882.1 - 0.034 13.4 0.2 0.034 13.4 0.2 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG13882.1 - 0.036 13.7 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 OAG13882.1 - 0.11 12.4 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Glyco_hydro_43 PF04616.14 OAG13883.1 - 4.9e-18 65.5 5.1 7.3e-18 64.9 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 OAG13883.1 - 0.00028 21.2 0.9 0.00059 20.1 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) Cnd2 PF05786.14 OAG13884.1 - 1.6e-280 933.2 6.5 1.9e-280 933.0 6.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 OAG13884.1 - 0.0074 16.5 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CAP PF00188.26 OAG13885.1 - 1.6e-19 71.0 3.3 4.5e-19 69.5 2.0 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Nop14 PF04147.12 OAG13886.1 - 0.002 16.4 12.3 0.002 16.4 12.3 2.4 2 1 0 2 2 2 1 Nop14-like family Sporozoite_P67 PF05642.11 OAG13886.1 - 9.1 4.2 8.6 18 3.2 8.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.32 OAG13887.1 - 8.3e-12 45.4 5.0 0.031 15.1 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat DHHC PF01529.20 OAG13888.1 - 0.41 10.8 1.8 0.99 9.5 1.8 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3543 PF12063.8 OAG13889.1 - 1.1e-80 270.7 0.1 1.8e-80 270.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 OAG13889.1 - 1.5e-61 208.1 0.0 3.5e-61 206.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13889.1 - 2.3e-43 148.4 0.0 4.7e-43 147.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG13889.1 - 0.44 10.4 3.7 0.9 9.4 0.0 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pro_isomerase PF00160.21 OAG13890.1 - 3.7e-50 170.3 0.2 8e-50 169.2 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAG13890.1 - 2.7e-11 43.8 0.2 0.00015 22.5 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13890.1 - 6.1e-06 26.5 0.0 0.06 13.7 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG13890.1 - 0.014 14.4 0.4 0.96 8.3 0.1 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_binding_1 PF01035.20 OAG13890.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain AAA PF00004.29 OAG13891.1 - 2.6e-42 144.4 0.0 4.4e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG13891.1 - 1.3e-11 44.1 0.1 3.2e-11 42.8 0.0 1.7 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAG13891.1 - 2.3e-11 43.5 0.1 9.5e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 OAG13891.1 - 1.1e-07 32.4 0.0 5.7e-05 23.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAG13891.1 - 1.4e-06 28.3 0.1 3.2e-05 23.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG13891.1 - 3e-06 27.5 0.0 9.5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG13891.1 - 7.3e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG13891.1 - 0.00018 21.8 0.1 0.0036 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG13891.1 - 0.00039 19.7 0.0 0.00085 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAG13891.1 - 0.00075 20.1 0.0 0.0031 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAG13891.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 OAG13891.1 - 0.0023 17.2 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAG13891.1 - 0.0034 17.6 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 OAG13891.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 OAG13891.1 - 0.0043 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 OAG13891.1 - 0.0048 16.9 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OAG13891.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 OAG13891.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAG13891.1 - 0.0073 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAG13891.1 - 0.0082 15.9 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAG13891.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAG13891.1 - 0.023 14.0 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 OAG13891.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG13891.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG13891.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 OAG13891.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 OAG13891.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG13891.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAG13891.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 OAG13891.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OAG13891.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M1 PF01433.20 OAG13892.1 - 2.9e-85 285.3 0.3 4.6e-85 284.6 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAG13892.1 - 2.6e-80 270.3 0.5 1.4e-79 267.9 0.0 2.2 2 1 1 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OAG13892.1 - 8.1e-52 176.1 2.4 2.5e-51 174.5 1.9 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 OAG13892.1 - 0.0011 19.0 0.1 0.0024 17.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Mor PF08765.11 OAG13892.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Mor transcription activator family Cytochrom_C1 PF02167.15 OAG13893.1 - 8.4e-93 310.1 0.0 1.1e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAG13893.1 - 0.0058 16.9 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAG13893.1 - 0.006 17.7 0.1 0.039 15.1 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c Acetyltransf_3 PF13302.7 OAG13894.1 - 6.9e-19 68.9 0.0 9.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG13894.1 - 0.0025 17.7 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.25 OAG13894.1 - 0.12 12.6 0.0 0.98 9.7 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family 3Beta_HSD PF01073.19 OAG13895.1 - 1.2e-58 198.3 0.0 1.6e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG13895.1 - 1.3e-33 116.5 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG13895.1 - 7.2e-17 61.8 0.0 2.5e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG13895.1 - 3.5e-15 55.9 0.2 3.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG13895.1 - 4.6e-13 48.9 0.0 7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG13895.1 - 8.7e-09 34.9 0.0 1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG13895.1 - 4.4e-08 33.2 0.0 6.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG13895.1 - 2.7e-06 27.4 0.1 6.3e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG13895.1 - 0.0065 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OAG13895.1 - 0.0077 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG13895.1 - 0.056 12.9 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Nitroreductase PF00881.24 OAG13895.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitroreductase family DUF2492 PF10678.9 OAG13895.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) eIF2A PF08662.11 OAG13896.1 - 1.2e-39 136.2 2.2 1.4e-35 122.9 0.1 4.2 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OAG13896.1 - 2.6e-05 23.9 0.4 6.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_28 PF17937.1 OAG13896.1 - 0.02 15.3 0.6 0.044 14.2 0.6 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 OAG13896.1 - 0.1 13.5 0.3 24 6.0 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_2 PF04059.12 OAG13896.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 Methyltr_RsmF_N PF17125.5 OAG13896.1 - 0.18 12.3 0.8 3.2 8.3 0.1 2.9 3 1 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF ArfGap PF01412.18 OAG13897.1 - 5.5e-33 113.5 1.0 1.9e-32 111.7 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OAG13897.1 - 1.6e-20 73.9 12.6 2.6e-20 73.2 12.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAG13897.1 - 1.8e-12 47.7 0.1 5.8e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OAG13897.1 - 0.14 12.5 1.2 1.3 9.4 1.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain CheZ PF04344.13 OAG13897.1 - 0.19 11.6 2.4 12 5.8 0.2 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ ATP11 PF06644.11 OAG13898.1 - 2.2e-95 319.5 0.2 2.6e-95 319.3 0.2 1.0 1 0 0 1 1 1 1 ATP11 protein CdiI_2 PF18593.1 OAG13898.1 - 0.004 17.8 0.1 0.7 10.6 0.0 2.7 2 0 0 2 2 2 1 CdiI immunity protein zf-C4H2 PF10146.9 OAG13898.1 - 1.9 8.8 8.3 4.3 7.6 8.3 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Pex2_Pex12 PF04757.14 OAG13899.1 - 6.4e-43 146.9 3.4 7.8e-43 146.6 3.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 OAG13899.1 - 5.5e-11 42.1 9.1 9.1e-11 41.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG13899.1 - 1.4e-10 41.4 9.4 2.2e-10 40.7 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG13899.1 - 8.1e-10 38.4 7.3 1.3e-09 37.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG13899.1 - 1.4e-09 37.8 2.6 1.4e-09 37.8 2.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG13899.1 - 1.6e-09 37.5 8.8 2.4e-09 36.9 8.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG13899.1 - 1.4e-07 31.3 6.3 2.9e-07 30.3 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG13899.1 - 1.8e-06 27.7 10.5 2.9e-06 27.0 10.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG13899.1 - 1.9e-06 28.1 6.8 3.6e-06 27.2 6.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAG13899.1 - 1.9e-05 24.7 7.8 3.5e-05 23.9 7.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OAG13899.1 - 0.01 16.0 9.0 0.018 15.2 9.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OAG13899.1 - 0.023 14.6 5.0 0.042 13.7 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OAG13899.1 - 0.032 14.3 2.4 0.056 13.5 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAG13899.1 - 0.087 12.6 3.9 0.21 11.3 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 OAG13899.1 - 0.089 12.6 6.7 0.17 11.7 6.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.15 OAG13899.1 - 0.22 11.7 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain Cauli_VI PF01693.16 OAG13900.1 - 1.2e-10 41.5 0.1 2.1e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3533 PF12051.8 OAG13902.1 - 5.8e-119 397.4 7.9 7.4e-119 397.0 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MFS_1 PF07690.16 OAG13903.1 - 1.4e-24 86.7 58.3 1.5e-23 83.3 46.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAG13903.1 - 0.0031 16.0 4.9 0.0031 16.0 4.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector Fungal_trans PF04082.18 OAG13906.1 - 6.6e-10 38.5 0.5 1.3e-09 37.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13906.1 - 3.2e-08 33.5 6.1 3.2e-08 33.5 6.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3740 PF12548.8 OAG13906.1 - 0.58 10.6 2.8 4.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Sulfatase protein Glyco_hydro_7 PF00840.20 OAG13907.1 - 1.9e-197 656.3 23.3 2.1e-197 656.1 23.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_79C PF16862.5 OAG13909.1 - 7.6e-25 87.8 0.1 1.3e-23 83.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain p450 PF00067.22 OAG13910.1 - 9e-67 225.8 0.0 1.1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DLP_helical PF18709.1 OAG13910.1 - 0.19 10.9 0.1 1.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin-like helical domain GDA1_CD39 PF01150.17 OAG13912.1 - 3.4e-95 319.2 0.0 4.3e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OAG13912.1 - 0.056 12.9 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF1547 PF07577.11 OAG13912.1 - 0.077 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) Fungal_trans PF04082.18 OAG13913.1 - 2.6e-18 66.0 0.0 5.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13913.1 - 8e-05 22.7 8.1 0.00013 22.0 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 OAG13914.1 - 2.5e-44 152.0 0.0 3.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG13914.1 - 0.0006 19.7 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG13914.1 - 0.041 13.4 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 OAG13916.1 - 8.3e-32 110.5 28.0 8.3e-32 110.5 28.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1427 PF07235.11 OAG13916.1 - 3.9 7.5 7.6 4.7 7.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1427) Sugar_tr PF00083.24 OAG13917.1 - 4.6e-74 249.9 15.6 5.3e-74 249.7 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG13917.1 - 4e-20 72.0 21.2 4e-20 72.0 21.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAG13917.1 - 0.03 12.6 0.1 0.05 11.8 0.1 1.3 1 0 0 1 1 1 0 BT1 family Transket_pyr PF02779.24 OAG13917.1 - 1 9.0 3.3 0.55 9.9 0.2 2.0 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain UDPG_MGDP_dh PF00984.19 OAG13918.1 - 2.2e-19 69.4 0.0 5.1e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 OAG13918.1 - 2.2e-19 69.8 2.0 8.1e-17 61.4 2.0 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 OAG13918.1 - 4.3e-08 33.5 0.3 7.4e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltr_RsmB-F PF01189.17 OAG13918.1 - 0.0021 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F UDPG_MGDP_dh_C PF03720.15 OAG13918.1 - 0.003 18.0 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 OAG13918.1 - 0.005 17.4 0.2 0.023 15.3 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG13918.1 - 0.0094 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 OAG13918.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OAG13918.1 - 0.068 13.0 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAG13918.1 - 0.089 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 OAG13918.1 - 0.11 11.7 0.5 0.21 10.9 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OAG13918.1 - 0.17 12.6 0.0 0.42 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 OAG13919.1 - 3.3e-37 128.3 4.7 3.1e-26 92.1 2.7 2.4 1 1 1 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 OAG13919.1 - 3.6e-07 30.2 0.0 0.0033 17.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAG13919.1 - 1.1e-05 25.5 8.4 1.1e-05 25.5 8.4 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG13919.1 - 3.9e-05 23.6 0.0 0.026 14.4 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Sarcolipin PF05366.11 OAG13919.1 - 0.46 10.2 5.2 1.2 8.9 5.2 1.7 1 0 0 1 1 1 0 Sarcolipin Polysacc_deac_1 PF01522.21 OAG13920.1 - 5.4e-23 81.2 0.0 9.4e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG13920.1 - 2.3e-20 72.7 68.4 5e-07 30.1 19.4 3.6 3 0 0 3 3 3 3 Chitin recognition protein Glyco_hydro_57 PF03065.15 OAG13920.1 - 0.041 13.1 0.0 0.093 11.9 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAG13920.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) AstA PF04958.12 OAG13921.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit HET PF06985.11 OAG13922.1 - 1.3e-23 84.0 0.5 1.6e-23 83.7 0.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.18 OAG13924.1 - 4e-25 88.7 15.4 1e-20 74.3 12.6 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein YL1 PF05764.13 OAG13924.1 - 0.0029 17.8 1.8 0.0029 17.8 1.8 2.3 2 0 0 2 2 2 1 YL1 nuclear protein EMP70 PF02990.16 OAG13924.1 - 0.11 11.2 1.0 0.16 10.6 1.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 BORCS6 PF10157.9 OAG13924.1 - 1.1 9.5 5.3 1.7 8.8 0.2 2.8 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 6 PhoLip_ATPase_C PF16212.5 OAG13927.1 - 6.3e-70 235.8 21.9 6.3e-70 235.8 21.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG13927.1 - 1.7e-26 91.7 3.5 1.7e-23 82.1 0.4 2.9 2 0 0 2 2 2 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG13927.1 - 6.5e-14 52.7 0.0 7.5e-05 23.1 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG13927.1 - 1.2e-12 47.8 0.0 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG13927.1 - 8.4e-08 31.9 0.0 4.4e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG13927.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HET PF06985.11 OAG13928.1 - 2e-21 76.9 0.0 3.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.28 OAG13929.1 - 1.3e-83 281.6 0.0 1.8e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG13929.1 - 9.7e-08 32.1 0.2 1.6e-06 28.2 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG13929.1 - 0.00038 20.0 0.1 0.00071 19.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family HET PF06985.11 OAG13931.1 - 1.4e-19 70.9 0.2 2.2e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1910 PF08928.10 OAG13931.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Phosducin PF02114.16 OAG13932.1 - 7.5e-12 44.7 0.0 4.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Phosducin SIP1 PF04938.12 OAG13932.1 - 0.1 12.3 0.0 1.8 8.2 0.0 2.4 1 1 1 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) WD40 PF00400.32 OAG13933.1 - 3.8e-38 128.8 20.7 1.5e-05 25.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13933.1 - 1.7e-16 60.3 0.0 0.00034 20.8 0.1 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG13933.1 - 8e-05 22.6 0.0 0.038 13.9 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG13933.1 - 0.0013 18.1 0.0 0.034 13.5 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 OAG13933.1 - 0.086 11.3 0.0 0.17 10.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain A_deaminase PF00962.22 OAG13934.1 - 6.1e-31 107.9 0.0 7.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase NACHT PF05729.12 OAG13936.1 - 8.3e-09 35.6 1.8 1.6e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 NACHT domain KIX_2 PF16987.5 OAG13936.1 - 1.8e-07 31.1 0.1 1.8e-07 31.1 0.1 3.2 3 0 0 3 3 2 1 KIX domain AAA_22 PF13401.6 OAG13936.1 - 0.00013 22.3 0.3 0.0013 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG13936.1 - 0.00021 21.8 3.2 0.0016 18.9 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.14 OAG13936.1 - 0.0017 17.7 1.2 0.0084 15.4 0.0 2.5 3 0 0 3 3 3 1 KAP family P-loop domain RNA_helicase PF00910.22 OAG13936.1 - 0.015 15.7 1.4 0.29 11.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 OAG13936.1 - 0.042 14.4 0.4 1.1 9.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAG13936.1 - 0.056 12.6 1.1 0.21 10.7 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 OAG13936.1 - 0.091 13.2 0.1 0.091 13.2 0.1 2.2 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 OAG13936.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NTPase VirK PF06903.12 OAG13936.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 VirK protein WRKY PF03106.15 OAG13936.1 - 0.26 11.5 3.2 0.36 11.1 1.1 2.4 2 0 0 2 2 1 0 WRKY DNA -binding domain AAA_33 PF13671.6 OAG13936.1 - 0.32 11.1 3.1 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Thioredoxin_11 PF18078.1 OAG13936.1 - 0.5 10.5 4.7 1.8 8.7 4.7 1.9 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain TUDOR PF00567.24 OAG13936.1 - 0.78 9.8 5.7 2.1 8.4 5.7 1.7 1 0 0 1 1 1 0 Tudor domain EIIBC-GUT_N PF03612.14 OAG13936.1 - 0.96 9.2 7.4 2.3 7.9 7.4 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ABC_tran PF00005.27 OAG13936.1 - 1.7 9.2 0.0 1.7 9.2 0.0 3.1 3 1 0 3 3 1 0 ABC transporter TFIIA PF03153.13 OAG13936.1 - 5 7.0 27.3 9.3 6.1 27.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phosducin PF02114.16 OAG13936.1 - 5.1 6.0 9.7 11 4.8 9.5 1.6 2 0 0 2 2 2 0 Phosducin SNF2_N PF00176.23 OAG13937.1 - 6.7e-63 212.5 0.5 1.1e-62 211.8 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG13937.1 - 4.1e-12 46.4 0.0 1e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG13937.1 - 1.2e-06 28.6 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAG13937.1 - 0.00065 19.4 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase EF-hand_7 PF13499.6 OAG13938.1 - 0.0054 17.2 2.3 0.027 14.9 0.5 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG13938.1 - 0.013 15.0 0.2 0.046 13.3 0.2 2.0 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 OAG13938.1 - 0.039 13.8 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OAG13938.1 - 0.17 11.9 4.2 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain P5-ATPase PF12409.8 OAG13938.1 - 0.18 11.9 0.8 0.39 10.8 0.8 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter Aminotran_1_2 PF00155.21 OAG13939.1 - 1.5e-58 198.8 0.0 2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 OAG13939.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Homeodomain PF00046.29 OAG13940.1 - 1.2e-19 69.9 4.1 2.4e-19 68.9 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG13940.1 - 0.00093 19.0 0.6 0.0025 17.7 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain MDM10 PF12519.8 OAG13941.1 - 1.5e-147 492.2 2.6 5e-129 431.2 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 OAG13941.1 - 2.7e-07 30.3 0.0 0.03 13.8 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic porin RL10P_insert PF17777.1 OAG13942.1 - 3.1e-24 84.8 0.0 6.2e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAG13942.1 - 5.1e-20 71.5 0.1 7.8e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Miga PF10265.9 OAG13943.1 - 3.6 6.4 5.8 4.1 6.3 5.8 1.0 1 0 0 1 1 1 0 Mitoguardin DUF515 PF04415.12 OAG13943.1 - 6.9 4.9 13.2 7.5 4.8 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CorA PF01544.18 OAG13944.1 - 0.0013 18.1 0.8 0.004 16.5 0.1 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3787 PF12655.7 OAG13944.1 - 0.028 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) COMPASS-Shg1 PF05205.12 OAG13945.1 - 4.5e-20 72.3 0.0 4.5e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.18 OAG13947.1 - 1.4e-68 231.3 0.0 1.8e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Peptidase_S8 PF00082.22 OAG13951.1 - 4.2e-18 65.6 0.4 1.5e-17 63.8 0.4 1.8 1 1 0 1 1 1 1 Subtilase family CheR_N PF03705.15 OAG13951.1 - 0.073 12.8 2.8 0.16 11.8 0.0 2.9 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain Pkinase PF00069.25 OAG13952.1 - 1.3e-26 93.6 0.0 2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13952.1 - 3.3e-12 46.2 0.0 5.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Prok-RING_4 PF14447.6 OAG13952.1 - 0.31 10.9 2.8 1.7 8.6 0.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DOT1 PF08123.13 OAG13954.1 - 8.9e-55 185.4 0.0 1.4e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Ndc1_Nup PF09531.10 OAG13955.1 - 0.68 8.6 12.5 0.9 8.1 12.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 OAG13955.1 - 2.1 6.5 18.5 2.5 6.3 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 OAG13955.1 - 7 6.8 12.9 13 5.9 12.9 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RhoGAP PF00620.27 OAG13957.1 - 3.2e-36 124.4 0.0 5e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.15 OAG13958.1 - 8.5e-20 70.2 7.1 1.2e-19 69.7 7.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OAG13958.1 - 0.00062 19.5 6.2 0.0018 18.0 6.2 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Hormone_recep PF00104.30 OAG13958.1 - 0.041 13.5 2.4 0.046 13.3 2.4 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor CorA PF01544.18 OAG13961.1 - 3.7e-11 42.9 0.1 5.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Virul_fac_BrkB PF03631.15 OAG13961.1 - 0.00043 20.0 0.9 0.00069 19.3 0.9 1.2 1 0 0 1 1 1 1 Virulence factor BrkB FtsX PF02687.21 OAG13961.1 - 0.012 16.1 0.1 0.07 13.6 0.0 2.2 2 0 0 2 2 2 0 FtsX-like permease family EMC3_TMCO1 PF01956.16 OAG13961.1 - 0.02 14.6 0.5 0.5 10.1 0.1 2.6 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like MASE4 PF17158.4 OAG13961.1 - 0.024 13.9 0.6 0.04 13.2 0.6 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain MscS_TM PF12794.7 OAG13961.1 - 0.027 13.3 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 VPS53_C PF16854.5 OAG13961.1 - 0.043 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus ERGIC_N PF13850.6 OAG13961.1 - 0.21 12.0 0.2 0.6 10.5 0.1 1.9 1 1 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SPC12 PF06645.13 OAG13961.1 - 0.53 10.4 3.8 7.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) F-box-like PF12937.7 OAG13962.1 - 9.6e-06 25.4 0.4 3.4e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 OAG13962.1 - 0.0063 16.4 1.8 0.16 11.9 1.7 3.0 2 1 0 2 2 2 1 F-box domain CRCB PF02537.15 OAG13964.1 - 5.1e-39 132.5 7.5 1e-22 80.3 8.9 2.8 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 OAG13965.1 - 1.3e-73 246.8 0.0 1.5e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG13965.1 - 3.3e-07 29.9 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 OAG13965.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding ADC PF06314.11 OAG13966.1 - 1.9e-43 148.7 0.0 2.5e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HET PF06985.11 OAG13967.1 - 1.7e-24 86.8 0.3 1.9e-24 86.7 0.3 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-CHY PF05495.12 OAG13968.1 - 3.2e-09 37.2 16.5 5e-09 36.5 16.5 1.4 1 0 0 1 1 1 1 CHY zinc finger IBR PF01485.21 OAG13968.1 - 0.008 16.4 1.7 0.008 16.4 1.7 2.3 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain TIM PF00121.18 OAG13969.1 - 4.3e-89 298.1 0.1 4.9e-89 297.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OAG13969.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 CutC family PEX-1N PF09262.11 OAG13969.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Arm-DNA-bind_3 PF13356.6 OAG13969.1 - 0.17 12.3 0.2 0.4 11.1 0.1 1.7 2 0 0 2 2 2 0 Arm DNA-binding domain L51_S25_CI-B8 PF05047.16 OAG13970.1 - 7.3e-15 54.6 0.1 1.2e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 OAG13971.1 - 3.3e-27 94.9 1.0 5.3e-27 94.3 1.0 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OAG13971.1 - 2.3e-16 59.4 0.0 4.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG13971.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_8 PF11835.8 OAG13971.1 - 0.11 12.7 0.0 0.61 10.3 0.0 1.9 1 1 0 1 1 1 0 RRM-like domain Abhydrolase_3 PF07859.13 OAG13975.1 - 6.2e-55 186.3 0.1 8.3e-55 185.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG13975.1 - 4.9e-12 45.5 0.3 1.5e-11 43.9 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG13975.1 - 0.0023 17.5 0.0 0.0067 15.9 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG13975.1 - 0.0031 16.4 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 OAG13975.1 - 0.0081 14.9 0.0 0.03 13.0 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Eno-Rase_NADH_b PF12242.8 OAG13975.1 - 0.068 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 OAG13976.1 - 4.1e-51 173.8 1.2 4.6e-51 173.6 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13976.1 - 2.8e-45 154.2 0.5 3.5e-45 153.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG13976.1 - 5.5e-13 49.2 0.4 7.6e-13 48.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG13976.1 - 0.0053 17.0 0.2 0.019 15.3 0.1 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 OAG13976.1 - 0.0076 15.7 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) AdoHcyase_NAD PF00670.21 OAG13976.1 - 0.091 12.8 0.3 0.27 11.3 0.2 1.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NmrA PF05368.13 OAG13978.1 - 4.9e-12 45.9 0.0 6.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13978.1 - 5e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG13978.1 - 0.039 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG13978.1 - 0.051 13.8 0.0 0.34 11.2 0.0 2.4 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 OAG13979.1 - 3e-08 33.6 8.5 5.8e-08 32.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG13979.1 - 0.0027 16.6 0.1 0.0042 15.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nup192 PF11894.8 OAG13980.1 - 0 1457.2 2.2 0 1457.0 2.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 OAG13981.1 - 5.3e-51 173.8 0.8 1.4e-50 172.5 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAG13981.1 - 2.8e-32 111.9 0.3 2.3e-30 105.7 0.0 4.1 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAG13981.1 - 2.8e-11 43.0 0.1 5.5e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 OAG13981.1 - 4.5e-05 22.8 6.0 0.00036 19.9 6.0 2.3 1 1 0 1 1 1 1 FAT domain AP_endonuc_2 PF01261.24 OAG13981.1 - 0.073 12.5 0.0 5.8 6.3 0.0 3.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel HET PF06985.11 OAG13982.1 - 5.8e-33 114.3 7.5 1.3e-29 103.4 7.5 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 14-3-3 PF00244.20 OAG13982.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein MAP65_ASE1 PF03999.12 OAG13985.1 - 4.2e-78 263.5 13.8 1.6e-77 261.6 14.2 1.5 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Takusan PF04822.13 OAG13985.1 - 0.81 9.6 9.8 0.068 13.1 1.6 3.2 3 1 0 3 3 3 0 Takusan Spectrin PF00435.21 OAG13985.1 - 6.4 7.3 23.6 0.17 12.4 2.7 4.9 4 1 0 5 5 5 0 Spectrin repeat Prominin PF05478.11 OAG13985.1 - 6.7 4.5 6.1 6.7 4.5 0.2 2.4 2 1 0 2 2 2 0 Prominin Bac_rhamnosid6H PF17389.2 OAG13986.1 - 1.5e-14 54.0 0.7 1.1e-12 47.9 0.3 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 OAG13986.1 - 0.00018 20.5 0.4 0.00028 19.9 0.4 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 OAG13986.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 OAG13986.1 - 0.039 12.6 0.2 0.072 11.8 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Vps16_N PF04841.13 OAG13987.1 - 1.2e-96 324.0 0.0 1.6e-96 323.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OAG13987.1 - 9.9e-85 284.4 0.1 1.8e-84 283.6 0.1 1.3 1 1 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OAG13987.1 - 0.00032 20.9 0.0 0.2 12.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 OAG13988.1 - 1.7e-51 175.1 0.1 2.9e-51 174.4 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Golgin_A5 PF09787.9 OAG13988.1 - 0.011 15.3 2.9 0.011 15.3 2.9 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 FAM184 PF15665.5 OAG13988.1 - 0.015 15.0 4.5 0.015 15.0 4.5 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 OAG13988.1 - 0.017 14.0 5.2 0.028 13.3 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkip-1 PF06878.11 OAG13988.1 - 0.038 14.1 1.3 0.071 13.2 1.3 1.4 1 0 0 1 1 1 0 Pkip-1 protein Shugoshin_N PF07558.11 OAG13988.1 - 0.052 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 OAG13988.1 - 0.073 13.7 1.3 0.46 11.1 0.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OAG13988.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.8 2 1 1 3 3 2 0 bZIP transcription factor FlxA PF14282.6 OAG13988.1 - 0.53 10.3 5.4 1.6 8.7 5.2 1.9 1 1 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.8 OAG13988.1 - 0.55 10.3 4.6 1.5 8.9 0.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SnAC PF14619.6 OAG13988.1 - 0.69 10.6 5.5 12 6.6 0.0 3.0 2 1 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex IFT20 PF14931.6 OAG13988.1 - 1.7 8.8 7.8 9.2 6.5 5.6 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DivIC PF04977.15 OAG13988.1 - 2 8.2 7.4 6.2 6.7 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator TT_ORF2 PF02957.15 OAG13988.1 - 3.2 8.7 7.4 8.2 7.4 7.4 1.7 1 0 0 1 1 1 0 TT viral ORF2 SpoU_methylase PF00588.19 OAG13989.1 - 4.9e-21 75.4 0.0 1.2e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Glyco_hydro_43 PF04616.14 OAG13990.1 - 9.8e-53 179.3 1.9 1.2e-52 179.1 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG13990.1 - 0.0041 16.7 0.1 0.031 13.9 0.1 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Aldedh PF00171.22 OAG13991.1 - 4.9e-144 480.3 0.0 6e-144 480.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 OAG13992.1 - 7.4e-09 35.8 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain cEGF PF12662.7 OAG13993.1 - 0.077 12.9 1.1 0.077 12.9 1.1 2.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_CA PF07645.15 OAG13993.1 - 0.33 11.2 6.1 2.2 8.5 6.1 2.1 1 1 0 1 1 1 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 OAG13993.1 - 0.37 11.1 7.6 2.5 8.4 7.6 2.2 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Cortex-I_coil PF09304.10 OAG13995.1 - 1.2 9.3 4.5 4.1 7.7 2.1 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil CN_hydrolase PF00795.22 OAG13996.1 - 1.2e-37 129.7 0.2 1.4e-37 129.4 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysM PF01476.20 OAG13998.1 - 6.1e-14 51.8 0.2 2.4e-06 27.5 0.1 2.6 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 OAG13999.1 - 1.3e-21 76.4 1.5 1.2e-05 25.3 0.2 4.4 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.12 OAG13999.1 - 0.074 13.3 5.5 4.9 7.5 0.3 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Tox-ODYAM1 PF15642.6 OAG13999.1 - 0.2 10.6 0.1 24 3.7 0.0 2.8 3 0 0 3 3 3 0 Toxin in Odyssella and Amoebophilus Methyltrans_SAM PF10672.9 OAG14000.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Glyco_hydro_18 PF00704.28 OAG14001.1 - 9.4e-71 239.1 0.9 1.6e-70 238.3 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG14001.1 - 1e-10 41.9 16.6 1e-10 41.9 16.6 5.2 4 2 0 4 4 4 2 Chitin recognition protein F-box-like PF12937.7 OAG14002.1 - 0.064 13.2 0.6 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 F-box-like Ank_4 PF13637.6 OAG14003.1 - 1.3e-06 28.8 0.0 1.7e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG14003.1 - 2.2e-06 27.9 0.2 0.075 13.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG14003.1 - 3.2e-05 24.4 0.0 4.9e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG14003.1 - 0.0082 16.4 0.1 0.016 15.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG14003.1 - 0.11 13.1 0.0 14 6.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat JmjC PF02373.22 OAG14004.1 - 1.5e-19 70.5 0.0 3.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.28 OAG14004.1 - 3.5e-09 37.3 0.0 4e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 SET domain HypA PF01155.19 OAG14004.1 - 0.65 10.0 3.0 0.65 10.0 0.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2635 PF10948.8 OAG14006.1 - 0.086 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) APH PF01636.23 OAG14011.1 - 5.7e-14 52.6 0.0 9.7e-14 51.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG14011.1 - 8.6e-06 25.5 0.0 3.3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 OAG14011.1 - 0.044 13.1 0.0 8.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain HET PF06985.11 OAG14013.1 - 0.00034 21.0 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myb_DNA-binding PF00249.31 OAG14014.1 - 1.5e-06 28.3 0.2 2.6e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG14014.1 - 0.031 14.5 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PBP1_TM PF14812.6 OAG14014.1 - 4.2 7.8 6.3 4 7.9 2.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 OAG14016.1 - 2.9e-49 167.9 36.5 2.9e-49 167.9 36.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14016.1 - 2.6e-13 49.7 26.1 6.5e-13 48.3 26.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter HLH PF00010.26 OAG14018.1 - 1.1e-13 50.9 0.4 2e-13 50.1 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CorA PF01544.18 OAG14019.1 - 6.9e-07 28.9 9.5 4.3e-06 26.3 1.3 3.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Gly_acyl_tr_N PF06021.11 OAG14019.1 - 0.017 15.3 0.5 0.035 14.2 0.1 1.7 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Pec_lyase_C PF00544.19 OAG14020.1 - 1.1e-44 152.5 13.1 1.6e-44 152.0 13.1 1.2 1 0 0 1 1 1 1 Pectate lyase P_gingi_FimA PF06321.11 OAG14020.1 - 0.4 10.8 9.2 0.35 11.0 1.0 2.3 2 0 0 2 2 2 0 Major fimbrial subunit protein (FimA) Mito_carr PF00153.27 OAG14021.1 - 7.5e-39 131.6 6.1 1.3e-15 57.0 0.7 4.2 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG14021.1 - 0.49 9.5 2.7 0.25 10.5 0.1 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease zf-TRAF PF02176.18 OAG14022.1 - 1.1e-10 42.1 20.5 4.6e-05 24.0 1.4 4.2 1 1 3 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 OAG14022.1 - 1.4e-06 28.1 7.3 1.4e-06 28.1 7.3 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG14022.1 - 2.2e-06 27.7 8.6 2.2e-06 27.7 8.6 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG14022.1 - 4.5e-06 26.6 8.6 4.5e-06 26.6 8.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG14022.1 - 4.6e-06 26.5 8.9 4.6e-06 26.5 8.9 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG14022.1 - 8.6e-06 26.0 10.4 8.6e-06 26.0 10.4 3.3 2 1 2 4 4 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAG14022.1 - 2e-05 24.4 8.2 2e-05 24.4 8.2 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG14022.1 - 8.1e-05 22.4 9.1 8.1e-05 22.4 9.1 2.6 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG14022.1 - 0.00038 20.2 9.8 0.00038 20.2 9.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ACC PF17848.1 OAG14022.1 - 0.028 14.5 0.2 0.028 14.5 0.2 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 OAG14022.1 - 4.5 6.9 15.0 0.095 12.3 0.6 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger SNARE PF05739.19 OAG14023.1 - 2.2e-06 27.6 1.3 2.2e-06 27.6 1.3 1.7 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 OAG14023.1 - 0.011 15.4 1.1 0.029 14.1 1.1 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 CorA PF01544.18 OAG14023.1 - 0.012 14.9 0.0 0.012 14.9 0.0 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 OAG14023.1 - 0.027 14.5 3.3 0.053 13.6 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3246 PF11596.8 OAG14023.1 - 0.037 13.5 3.1 0.056 12.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Synaptobrevin PF00957.21 OAG14023.1 - 0.052 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Synaptobrevin HemX PF04375.14 OAG14023.1 - 0.07 12.4 4.9 0.29 10.4 0.2 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Allexi_40kDa PF05549.11 OAG14023.1 - 0.38 10.2 3.2 0.21 11.1 1.0 1.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein PBP1_TM PF14812.6 OAG14023.1 - 1.1 9.7 5.8 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LPP PF04728.13 OAG14023.1 - 1.1 9.7 9.4 4.4 7.8 1.2 3.8 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Med9 PF07544.13 OAG14023.1 - 1.2 9.3 5.5 8.9 6.5 0.4 2.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Mito_carr PF00153.27 OAG14024.1 - 1.2e-62 207.8 5.1 1.9e-22 79.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAG14024.1 - 6.5e-24 81.7 2.0 3e-07 29.5 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OAG14024.1 - 7.5e-23 79.0 4.8 6.1e-07 28.6 0.9 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OAG14024.1 - 1.7e-22 79.7 2.4 1.8e-12 47.5 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG14024.1 - 7.3e-20 69.1 5.0 2.2e-06 27.1 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OAG14024.1 - 1.7e-15 56.6 2.3 1.2e-08 34.7 0.1 3.8 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG14024.1 - 1.4e-09 38.3 0.0 1.7e-06 28.4 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OAG14024.1 - 0.00059 20.0 0.4 0.39 11.0 0.0 3.2 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_9 PF14658.6 OAG14024.1 - 0.0045 17.3 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OAG14024.1 - 0.0052 16.7 1.1 0.14 12.1 0.1 2.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Serine_protease PF18405.1 OAG14024.1 - 0.068 12.3 0.2 2.2 7.4 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Cyclin_N PF00134.23 OAG14025.1 - 3.3e-14 52.7 2.6 2.3e-11 43.5 0.5 2.6 2 1 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAG14025.1 - 0.028 14.8 0.3 0.088 13.2 0.3 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 OAG14025.1 - 0.035 14.2 0.5 0.078 13.0 0.5 1.7 1 1 0 1 1 1 0 Transcription factor TFIIB repeat DUF4452 PF14618.6 OAG14026.1 - 2.1e-72 242.5 12.3 2.7e-72 242.2 12.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Fibrillin_U_N PF18193.1 OAG14027.1 - 0.14 12.3 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Vfa1 PF08432.10 OAG14029.1 - 3.3 8.0 12.0 3.7 7.8 12.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAD_binding_4 PF01565.23 OAG14030.1 - 1.2e-20 73.7 1.6 2.3e-20 72.7 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG14030.1 - 3.6e-09 36.6 0.2 7.4e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ring_hydroxyl_A PF00848.19 OAG14031.1 - 1.7e-24 87.0 5.4 5.8e-22 78.7 5.4 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG14031.1 - 1.9e-13 50.1 0.0 4.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Beach PF02138.18 OAG14031.1 - 0.067 12.6 0.2 0.099 12.0 0.2 1.2 1 0 0 1 1 1 0 Beige/BEACH domain zf-piccolo PF05715.13 OAG14031.1 - 0.77 10.0 3.2 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger DAO PF01266.24 OAG14034.1 - 1.1e-35 123.9 0.0 1.3e-35 123.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG14034.1 - 6.2e-06 25.7 0.0 0.0022 17.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG14034.1 - 4e-05 23.8 0.1 0.00014 22.0 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG14034.1 - 9.4e-05 21.8 0.0 0.049 12.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OAG14034.1 - 0.00082 18.8 0.2 0.0024 17.3 0.1 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.20 OAG14034.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 OAG14034.1 - 0.0035 16.2 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAG14034.1 - 0.007 15.1 0.2 1.3 7.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OAG14034.1 - 0.0071 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG14034.1 - 0.021 14.8 0.6 0.24 11.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG14034.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OAG14034.1 - 0.031 14.5 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 OAG14034.1 - 0.036 13.6 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 OAG14034.1 - 0.044 12.9 0.2 0.085 11.9 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG14034.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAG14034.1 - 0.079 13.5 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IFS PF16718.5 OAG14034.1 - 0.22 11.6 0.0 0.38 10.8 0.0 1.2 1 0 0 1 1 1 0 Immunity factor for SPN FMO-like PF00743.19 OAG14035.1 - 3.4e-14 52.2 0.9 2.2e-13 49.5 0.0 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG14035.1 - 1.4e-09 37.6 1.3 1.5e-07 31.0 0.0 3.6 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG14035.1 - 1.9e-06 27.2 1.7 2.9e-05 23.4 0.0 2.6 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG14035.1 - 0.00014 21.2 0.2 0.017 14.4 0.4 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG14035.1 - 0.011 15.8 0.1 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG14035.1 - 0.88 9.1 4.8 5.1 6.6 0.0 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase HAT PF02184.16 OAG14036.1 - 2e-25 88.4 71.7 4.3e-14 52.2 2.4 14.5 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OAG14036.1 - 5.6e-24 82.8 22.8 0.015 16.0 0.1 11.2 7 3 5 12 12 11 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAG14036.1 - 1.8e-17 63.6 0.1 0.0005 20.5 0.0 7.4 6 2 1 8 8 7 4 Tetratricopeptide repeat Suf PF05843.14 OAG14036.1 - 5.2e-14 52.9 16.2 0.00085 19.4 0.3 6.2 2 2 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAG14036.1 - 6e-10 38.8 3.0 0.26 11.8 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG14036.1 - 2.9e-07 30.0 8.1 0.18 11.0 1.5 6.2 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG14036.1 - 3.5e-07 29.9 0.2 19 5.8 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG14036.1 - 2.1e-06 27.9 9.3 8 6.8 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG14036.1 - 2.6e-05 24.8 10.8 0.78 10.4 0.0 7.6 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG14036.1 - 7.6e-05 22.5 11.3 4.5 7.6 0.0 9.4 12 0 0 12 12 11 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG14036.1 - 0.00073 18.8 23.8 0.23 10.5 0.0 6.2 3 3 2 6 6 6 2 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 OAG14036.1 - 0.0075 16.3 21.3 0.11 12.6 1.7 7.0 6 2 1 7 7 7 1 U3 small nucleolar RNA-associated protein 6 QIL1 PF15884.5 OAG14036.1 - 0.14 12.8 0.1 2.7 8.6 0.0 3.0 3 0 0 3 3 2 0 MICOS complex subunit MIC13, QIL1 TPR_10 PF13374.6 OAG14036.1 - 0.3 11.0 17.5 14 5.7 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG14036.1 - 0.71 10.6 19.7 53 4.8 0.1 8.6 11 0 0 11 11 8 0 Tetratricopeptide repeat Nop PF01798.18 OAG14037.1 - 2e-64 217.2 0.0 2.7e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAG14037.1 - 8.7e-44 149.3 1.7 2.1e-43 148.1 1.7 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 OAG14037.1 - 2.9 6.3 4.4 4.5 5.7 4.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA_anti_2 PF13742.6 OAG14039.1 - 0.14 12.4 0.0 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF4302 PF14135.6 OAG14039.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) DUF5559 PF17714.1 OAG14040.1 - 0.018 14.9 0.3 0.029 14.3 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) PIN_5 PF08745.11 OAG14040.1 - 0.17 11.3 0.2 9.3 5.6 0.0 2.4 2 0 0 2 2 2 0 PINc domain ribonuclease Tr-sialidase_C PF11052.8 OAG14040.1 - 0.57 10.4 0.1 0.57 10.4 0.1 2.5 3 0 0 3 3 3 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal LysM PF01476.20 OAG14041.1 - 3.9e-27 94.0 0.0 1.1e-09 38.2 0.0 4.3 4 0 0 4 4 4 4 LysM domain Glyco_hydro_18 PF00704.28 OAG14042.1 - 8.9e-67 226.0 0.6 8.9e-67 226.0 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG14042.1 - 7.7e-09 35.9 9.3 7.7e-09 35.9 9.3 5.5 7 1 0 7 7 7 2 Chitin recognition protein PYRIN PF02758.16 OAG14043.1 - 0.018 15.2 0.2 0.16 12.1 0.0 2.3 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Pex24p PF06398.11 OAG14043.1 - 0.083 11.9 1.9 0.17 10.8 2.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DGF-1_C PF11040.8 OAG14044.1 - 0.02 14.9 0.1 0.02 14.9 0.1 2.6 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-DBF PF07535.12 OAG14044.1 - 0.029 14.5 2.4 0.029 14.5 2.4 6.3 7 0 0 7 7 7 0 DBF zinc finger Zn_ribbon_SprT PF17283.2 OAG14044.1 - 0.31 11.0 6.8 18 5.3 0.0 4.2 3 1 0 3 3 3 0 SprT-like zinc ribbon domain HNH_5 PF14279.6 OAG14044.1 - 0.31 10.9 11.5 2.6 7.9 0.0 4.7 5 0 0 5 5 5 0 HNH endonuclease zf-met PF12874.7 OAG14044.1 - 9.3 6.8 39.1 0.37 11.2 0.7 8.2 7 1 0 7 7 7 0 Zinc-finger of C2H2 type Zn_clus PF00172.18 OAG14045.1 - 8.3e-08 32.2 10.1 1.3e-07 31.6 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 OAG14046.1 - 3.7e-13 48.8 7.0 7.6e-13 47.8 7.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAG14046.1 - 0.0016 18.6 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 OAG14046.1 - 0.044 13.9 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain WSC PF01822.19 OAG14047.1 - 1.8e-13 50.5 3.4 1.8e-13 50.5 3.4 2.0 2 0 0 2 2 2 1 WSC domain CBM_19 PF03427.13 OAG14048.1 - 7.1e-05 22.7 6.6 0.00042 20.2 6.6 2.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) LPMO_10 PF03067.15 OAG14048.1 - 0.0024 18.6 0.1 0.0051 17.5 0.1 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SNF5 PF04855.12 OAG14049.1 - 3.5e-87 292.1 0.0 4.8e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAG14049.1 - 7.1e-05 22.3 3.2 0.00016 21.2 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 OAG14049.1 - 1.5 8.6 8.3 15 5.4 3.4 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain AAA_23 PF13476.6 OAG14053.1 - 3.9 7.9 9.2 0.62 10.5 5.0 1.7 2 0 0 2 2 2 0 AAA domain SURF4 PF02077.15 OAG14054.1 - 7.7e-93 310.9 8.3 8.8e-93 310.8 8.3 1.0 1 0 0 1 1 1 1 SURF4 family IU_nuc_hydro PF01156.19 OAG14055.1 - 6.7e-44 150.7 0.0 4.7e-43 147.9 0.0 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Abhydrolase_3 PF07859.13 OAG14056.1 - 7.7e-18 65.1 0.1 7.4e-17 61.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG14056.1 - 1.3e-07 31.3 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 OAG14056.1 - 1.2e-06 28.3 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAG14056.1 - 6.7e-06 26.1 0.2 0.085 12.6 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase COesterase PF00135.28 OAG14056.1 - 0.00012 21.1 0.0 0.0003 19.8 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S15 PF02129.18 OAG14056.1 - 0.00016 21.4 0.4 0.00067 19.3 0.4 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 OAG14056.1 - 0.0049 15.8 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG14056.1 - 0.0067 15.7 0.1 0.017 14.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OAG14056.1 - 0.009 14.7 0.1 0.027 13.2 0.1 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 OAG14056.1 - 0.13 11.8 0.1 0.77 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 OAG14056.1 - 0.36 9.6 0.4 5.6 5.7 0.1 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Ank_2 PF12796.7 OAG14057.1 - 1.8e-27 95.7 0.1 8.2e-08 32.7 0.2 6.2 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG14057.1 - 3.6e-22 76.1 11.6 0.032 14.7 0.0 11.0 11 0 0 11 11 10 6 Ankyrin repeat Ank_4 PF13637.6 OAG14057.1 - 1.8e-21 76.2 3.4 0.0004 20.9 0.2 8.2 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Pkinase PF00069.25 OAG14057.1 - 1.5e-20 73.7 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14057.1 - 3.2e-19 69.2 0.0 2.3e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 OAG14057.1 - 4.4e-13 49.2 10.2 0.075 13.4 0.0 7.9 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG14057.1 - 2.3e-05 24.6 24.1 0.67 10.5 0.1 9.6 13 0 0 13 13 11 2 Ankyrin repeat zf-RanBP PF00641.18 OAG14057.1 - 9.7e-05 21.6 0.3 0.00024 20.3 0.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Kdo PF06293.14 OAG14057.1 - 0.021 14.2 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1843 PF08898.10 OAG14057.1 - 0.039 14.4 1.8 2.9 8.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Pkinase_fungal PF17667.1 OAG14057.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Transcrip_reg PF01709.20 OAG14057.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HeLo PF14479.6 OAG14058.1 - 4.5e-21 75.6 2.1 8.3e-21 74.8 2.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation DNA_gyraseB PF00204.25 OAG14058.1 - 0.013 15.0 0.3 0.029 13.8 0.1 1.7 2 0 0 2 2 2 0 DNA gyrase B Baculo_ME53 PF06061.11 OAG14060.1 - 0.0021 17.4 0.0 0.0029 16.9 0.0 1.1 1 0 0 1 1 1 1 Baculoviridae ME53 GIY-YIG PF01541.24 OAG14060.1 - 0.031 14.5 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain WD40 PF00400.32 OAG14061.1 - 3.8e-19 68.7 19.1 2.2e-05 25.1 0.2 6.8 6 2 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14061.1 - 1.8e-11 44.2 7.7 2.2e-05 24.7 0.2 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 OAG14061.1 - 0.0076 16.2 12.7 0.19 11.7 1.3 3.5 1 1 2 3 3 3 2 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.6 OAG14061.1 - 0.034 14.4 1.8 1.8 9.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Mod_r PF07200.13 OAG14062.1 - 8.9e-33 113.5 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3263 PF11662.8 OAG14062.1 - 0.058 13.2 0.2 0.058 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) Glyco_hydro_2_N PF02837.18 OAG14064.1 - 8.7e-11 42.0 0.0 1.2e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro2_C5 PF18565.1 OAG14065.1 - 2.7e-21 75.3 0.1 4.8e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 OAG14065.1 - 1.7e-16 59.9 0.0 4.4e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Pkinase PF00069.25 OAG14066.1 - 1.6e-60 204.7 0.0 2e-59 201.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14066.1 - 2.9e-26 92.3 0.3 6e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG14066.1 - 2.5e-05 23.4 0.2 4.5e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG14066.1 - 0.00038 20.5 0.1 0.035 14.0 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG14066.1 - 0.00054 19.4 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG14066.1 - 0.01 15.1 0.5 0.021 14.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like PA28_alpha PF02251.18 OAG14066.1 - 0.061 13.4 0.2 5.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit RIO1 PF01163.22 OAG14066.1 - 0.092 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DNA_RNApol_7kD PF03604.13 OAG14067.1 - 1.3e-17 63.1 5.7 1.6e-17 62.8 5.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 OAG14067.1 - 0.0069 16.4 0.3 0.0069 16.4 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MCM_OB PF17207.3 OAG14067.1 - 0.0099 15.7 0.3 0.01 15.7 0.3 1.0 1 0 0 1 1 1 1 MCM OB domain TFIIS_C PF01096.18 OAG14067.1 - 0.013 15.3 1.1 3.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CRD PF17979.1 OAG14067.1 - 0.016 15.3 0.4 0.016 15.3 0.4 1.1 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions DZR PF12773.7 OAG14067.1 - 0.02 14.9 0.8 0.027 14.5 0.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 OAG14067.1 - 0.052 13.5 1.9 0.53 10.3 0.5 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_13 PF09855.9 OAG14067.1 - 0.061 13.5 0.3 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) LRV_FeS PF05484.11 OAG14067.1 - 0.063 13.3 0.2 0.063 13.3 0.2 1.9 1 1 1 2 2 2 0 LRV protein FeS4 cluster DUF951 PF06107.11 OAG14067.1 - 0.078 12.9 1.8 0.56 10.2 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF35_N PF12172.8 OAG14067.1 - 0.21 11.5 3.7 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 OAG14067.1 - 0.28 11.2 0.5 0.28 11.2 0.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OAG14067.1 - 0.32 10.6 1.7 6.7 6.4 0.2 2.1 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OAG14067.1 - 0.6 10.3 5.3 3.2 7.9 5.2 2.0 1 1 0 1 1 1 0 Zinc ribbon domain Peptidase_S8 PF00082.22 OAG14068.1 - 3.8e-14 52.6 0.0 8.2e-14 51.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family NACHT PF05729.12 OAG14070.1 - 1.1e-05 25.4 0.1 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 OAG14070.1 - 0.0099 16.4 0.0 0.74 10.5 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 OAG14070.1 - 0.065 13.5 0.0 1 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain HET PF06985.11 OAG14071.1 - 4.4e-23 82.2 0.6 5.3e-23 82.0 0.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fascin PF06268.13 OAG14072.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Fascin domain adh_short_C2 PF13561.6 OAG14075.1 - 3.4e-57 193.7 0.6 4.7e-57 193.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG14075.1 - 9.7e-46 155.7 0.3 1.2e-45 155.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG14075.1 - 1.2e-08 35.1 0.3 3.2e-08 33.7 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG14075.1 - 0.0025 17.3 0.1 0.0033 16.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG14075.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1840 PF08895.11 OAG14076.1 - 0.0066 16.8 3.1 0.012 15.9 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1840) MFS_1 PF07690.16 OAG14078.1 - 2.5e-41 141.8 47.9 2.5e-41 141.8 47.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG14078.1 - 6e-12 44.8 19.5 7.6e-12 44.4 19.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG14078.1 - 0.051 11.9 19.2 0.95 7.7 18.5 2.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family 14-3-3 PF00244.20 OAG14080.1 - 1.3e-07 31.4 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 14-3-3 protein Prp19 PF08606.11 OAG14080.1 - 0.058 13.4 0.9 0.52 10.3 0.2 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like NmrA PF05368.13 OAG14081.1 - 2.2e-25 89.6 0.0 2.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14081.1 - 1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG14081.1 - 4.2e-06 26.4 0.0 1.7e-05 24.5 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG14081.1 - 0.0041 17.4 0.0 0.0099 16.1 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG14081.1 - 0.012 16.0 0.1 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG14081.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Img2 PF05046.14 OAG14081.1 - 0.14 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Zn_clus PF00172.18 OAG14082.1 - 3e-05 24.0 9.9 5.2e-05 23.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG14082.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain TauD PF02668.16 OAG14083.1 - 1.3e-56 192.4 0.8 1.5e-56 192.2 0.8 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HU-CCDC81_euk_2 PF18289.1 OAG14083.1 - 0.0093 16.1 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 NmrA PF05368.13 OAG14084.1 - 3.1e-35 121.8 0.1 9e-35 120.3 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14084.1 - 4.3e-10 39.8 0.0 6.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 OAG14085.1 - 2e-42 145.6 0.1 2.7e-31 108.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 FAA_hydrolase PF01557.18 OAG14086.1 - 2e-61 207.4 0.0 3.5e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 OAG14086.1 - 1.6e-18 67.3 0.0 2.4e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG14086.1 - 1.5e-16 61.7 0.1 2.5e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG14086.1 - 1.4e-14 54.0 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAG14086.1 - 2.1e-06 27.7 0.0 6.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 OAG14086.1 - 0.0023 17.7 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 2 PGAP1-like protein LIDHydrolase PF10230.9 OAG14086.1 - 0.0033 17.0 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 OAG14086.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAG14086.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 OAG14087.1 - 1.3e-14 53.9 0.4 3e-14 52.7 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14087.1 - 2.2e-09 37.3 12.4 4.3e-09 36.3 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4359 PF14271.6 OAG14087.1 - 0.16 12.7 0.8 8.6 7.2 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) ABC_membrane PF00664.23 OAG14088.1 - 3.3e-85 286.1 39.3 2.5e-48 165.1 19.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG14088.1 - 5.9e-71 237.3 0.0 8.5e-35 120.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG14088.1 - 1.3e-13 50.9 0.4 5.5e-05 22.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAG14088.1 - 3.7e-09 35.9 0.6 0.0015 17.4 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAG14088.1 - 2e-08 33.8 2.8 0.0018 17.9 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG14088.1 - 2.4e-07 31.1 0.4 0.031 14.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG14088.1 - 2.6e-07 30.7 0.0 0.036 14.0 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG14088.1 - 7.9e-07 29.6 1.0 0.064 13.6 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG14088.1 - 1.5e-06 28.3 0.1 0.097 12.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAG14088.1 - 6.7e-06 25.8 0.1 0.16 11.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 OAG14088.1 - 2.2e-05 24.4 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OAG14088.1 - 3.9e-05 23.5 0.6 0.47 10.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAG14088.1 - 7.4e-05 22.1 0.2 0.29 10.4 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.6 OAG14088.1 - 0.0004 20.5 1.6 1.1 9.6 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAG14088.1 - 0.00076 20.0 0.2 0.14 12.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG14088.1 - 0.0017 18.4 0.0 0.45 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG14088.1 - 0.0024 18.1 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG14088.1 - 0.0025 18.1 0.0 0.67 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG14088.1 - 0.0032 17.0 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 OAG14088.1 - 0.0037 17.7 0.9 2.2 8.7 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG14088.1 - 0.0044 17.0 0.0 5.7 6.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG14088.1 - 0.0073 16.9 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAG14088.1 - 0.011 15.7 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 OAG14088.1 - 0.011 15.0 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 OAG14088.1 - 0.019 15.3 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 OAG14088.1 - 0.037 13.7 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 OAG14088.1 - 0.12 12.5 0.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 OAG14088.1 - 0.16 11.1 0.2 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain p450 PF00067.22 OAG14089.1 - 9.2e-59 199.4 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG14091.1 - 2.5e-48 165.0 0.0 7.4e-34 117.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 NAD_binding_4 PF07993.12 OAG14092.1 - 7.9e-05 21.9 0.0 0.00012 21.3 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 OAG14092.1 - 0.00031 20.4 0.1 0.00059 19.5 0.1 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14092.1 - 0.00072 19.5 0.1 0.0038 17.1 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG14092.1 - 0.0014 18.8 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG14092.1 - 0.024 14.1 0.2 0.1 12.0 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG14092.1 - 0.12 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HET PF06985.11 OAG14093.1 - 7.4e-12 45.8 0.5 1.5e-08 35.1 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG14094.1 - 3.8e-28 98.7 0.5 8.7e-28 97.5 0.5 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer4_8 PF13183.6 OAG14094.1 - 0.061 13.8 0.3 4 8.0 0.0 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain YozE_SAM_like PF06855.12 OAG14094.1 - 0.083 13.1 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 YozE SAM-like fold tRNA_int_end_N2 PF12928.7 OAG14095.1 - 2.6e-24 85.2 0.2 4.5e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAG14095.1 - 0.0079 15.8 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain DUF4185 PF13810.6 OAG14096.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Beta-lactamase PF00144.24 OAG14097.1 - 6.2e-37 127.6 0.7 9.7e-37 126.9 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAG14097.1 - 0.037 13.6 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family NmrA PF05368.13 OAG14098.1 - 8.5e-23 81.1 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14098.1 - 6.7e-17 62.0 0.1 1.3e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG14098.1 - 4.7e-05 23.8 0.1 9.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG14098.1 - 8.3e-05 22.9 0.1 0.00051 20.3 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG14098.1 - 0.00013 21.5 0.1 0.00029 20.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG14098.1 - 0.00018 21.7 0.1 0.00036 20.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 OAG14098.1 - 0.00025 20.2 0.0 0.00043 19.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 OAG14098.1 - 0.0012 19.0 0.2 0.004 17.3 0.2 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 OAG14098.1 - 0.02 14.3 0.5 0.061 12.8 0.1 1.9 2 1 0 2 2 2 0 short chain dehydrogenase Zn_protease PF05618.11 OAG14099.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease HTH_Tnp_Tc5 PF03221.16 OAG14100.1 - 2.6e-06 27.4 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain GAD-like PF08887.11 OAG14100.1 - 0.0053 16.5 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 GAD-like domain GREB1 PF15782.5 OAG14101.1 - 0.47 7.5 11.1 0.5 7.4 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3807 PF12720.7 OAG14101.1 - 1.5 9.1 19.8 2.3 8.4 19.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 OAG14101.1 - 2.2 6.9 14.6 2.7 6.6 14.6 1.1 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 OAG14101.1 - 3 8.1 14.7 4.9 7.4 14.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Misat_Tub_SegII PF10644.9 OAG14101.1 - 3.3 8.0 8.7 33 4.8 8.5 2.3 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain CPSF100_C PF13299.6 OAG14101.1 - 3.8 7.7 12.9 7.3 6.7 12.9 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Transformer PF06495.11 OAG14101.1 - 4.8 7.2 22.0 7.5 6.6 22.0 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein CDC45 PF02724.14 OAG14101.1 - 8.5 4.5 17.7 10 4.3 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 OAG14101.1 - 9.8 4.8 10.1 12 4.6 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Fil_haemagg PF05594.14 OAG14102.1 - 0.11 13.1 0.5 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 Haemagluttinin repeat CN_hydrolase PF00795.22 OAG14103.1 - 4.6e-42 144.2 0.0 5.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCV_T PF01571.21 OAG14104.1 - 8.2e-86 287.5 0.0 1.1e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAG14104.1 - 4.8e-22 77.7 0.3 8.9e-22 76.8 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 OAG14104.1 - 0.00073 19.7 0.1 0.012 15.8 0.0 2.8 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family V-ATPase_C PF03223.15 OAG14105.1 - 2.7e-129 431.8 0.6 3.1e-129 431.6 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cep57_MT_bd PF06657.13 OAG14105.1 - 0.042 14.3 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rx_N PF18052.1 OAG14105.1 - 0.062 13.6 0.3 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Rx N-terminal domain mRNA_cap_C PF03919.15 OAG14105.1 - 0.17 12.5 1.3 0.24 12.1 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain adh_short PF00106.25 OAG14106.1 - 1.1e-24 86.9 0.0 6e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14106.1 - 3.1e-17 62.9 0.0 5.7e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG14106.1 - 1.5e-05 25.0 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG14106.1 - 7.1e-05 22.4 0.1 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG14106.1 - 0.008 15.9 0.0 0.021 14.6 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KH_8 PF17903.1 OAG14107.1 - 3.4e-30 104.0 0.3 7.5e-30 102.9 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain SET PF00856.28 OAG14108.1 - 9.4e-10 39.1 0.0 1.8e-09 38.2 0.0 1.7 2 1 0 2 2 2 1 SET domain SWM_repeat PF13753.6 OAG14108.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative flagellar system-associated repeat TPR_8 PF13181.6 OAG14108.1 - 0.072 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG14108.1 - 0.77 9.9 3.6 0.7 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.11 OAG14109.1 - 1.2e-27 97.1 1.4 1.9e-27 96.4 1.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.11 OAG14110.1 - 0.002 18.2 2.0 0.0031 17.6 2.0 1.2 1 0 0 1 1 1 1 Podoplanin FeoB_associated PF12669.7 OAG14110.1 - 0.038 14.4 0.1 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glyco_hydro_31 PF01055.26 OAG14111.1 - 3e-130 435.4 4.7 4.4e-130 434.8 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG14111.1 - 1.6e-27 96.0 0.0 3.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG14111.1 - 1.5 9.2 6.7 0.36 11.2 0.7 2.8 3 0 0 3 3 3 0 Galactose mutarotase-like FeoB_associated PF12669.7 OAG14112.1 - 0.0047 17.3 0.2 0.0094 16.3 0.2 1.4 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein SKG6 PF08693.10 OAG14112.1 - 0.0084 15.5 1.6 0.0084 15.5 1.6 2.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain MccV PF17508.2 OAG14112.1 - 4 8.1 6.5 6.4 7.4 0.6 2.5 2 0 0 2 2 2 0 Microcin V bacteriocin NAD_binding_10 PF13460.6 OAG14113.1 - 1.5e-10 41.3 0.4 3.7e-10 40.0 0.4 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG14113.1 - 1e-08 35.0 0.2 6e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG14113.1 - 1.3e-08 34.7 0.3 2.5e-08 33.8 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 OAG14113.1 - 1.3e-05 25.3 0.6 2e-05 24.7 0.3 1.5 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG14113.1 - 2.3e-05 24.9 1.2 0.0002 21.8 0.5 2.5 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 OAG14113.1 - 0.00029 20.8 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAG14113.1 - 0.0037 16.4 0.7 0.041 13.0 0.2 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain ATR13 PF16829.5 OAG14113.1 - 0.004 17.5 0.1 0.0066 16.8 0.1 1.2 1 0 0 1 1 1 1 Avirulence protein ATR13, RxLR effector Semialdhyde_dh PF01118.24 OAG14113.1 - 0.0073 16.7 0.1 0.013 16.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG14113.1 - 0.0094 15.1 0.7 0.018 14.2 0.6 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein LpxI_N PF17930.1 OAG14113.1 - 0.017 15.0 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain DapB_N PF01113.20 OAG14113.1 - 0.028 14.5 1.0 0.075 13.2 1.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 OAG14113.1 - 0.034 14.6 0.7 0.072 13.5 0.7 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG14113.1 - 0.065 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 OAG14113.1 - 0.071 12.6 0.4 0.12 11.8 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG14113.1 - 0.079 11.9 0.1 0.22 10.5 0.1 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4015 PF13200.6 OAG14113.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Gp_dh_N PF00044.24 OAG14113.1 - 0.24 11.8 1.0 1.4 9.3 1.0 2.2 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 OAG14114.1 - 2e-45 155.3 3.9 3.1e-45 154.6 3.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14114.1 - 2.3e-07 30.8 5.6 4.2e-07 30.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Tnp_Tc5 PF03221.16 OAG14115.1 - 2.1e-09 37.2 0.0 5.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG14115.1 - 0.00036 20.2 0.1 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 OAG14115.1 - 0.0037 17.0 0.2 0.8 9.6 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_6 PF01418.17 OAG14115.1 - 0.0044 17.0 0.0 0.53 10.3 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain, rpiR family HTH_Tnp_Tc3_2 PF01498.18 OAG14115.1 - 0.021 15.1 0.3 0.056 13.7 0.1 1.8 2 0 0 2 2 2 0 Transposase GntR PF00392.21 OAG14115.1 - 0.024 14.3 0.0 0.94 9.2 0.0 2.5 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF2205 PF10224.9 OAG14116.1 - 3 7.9 7.0 11 6.0 0.4 2.4 2 0 0 2 2 2 0 Short coiled-coil protein HET PF06985.11 OAG14117.1 - 9.9e-34 116.8 1.8 1.9e-33 115.9 1.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACBP PF00887.19 OAG14119.1 - 1.1e-08 35.1 0.1 1.1e-08 35.1 0.1 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein PepSY_TM PF03929.16 OAG14119.1 - 0.034 13.8 1.2 0.042 13.5 0.6 1.4 1 1 0 1 1 1 0 PepSY-associated TM region ANAPC4_WD40 PF12894.7 OAG14121.1 - 0.00072 19.8 0.0 0.24 11.7 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UPF0061 PF02696.14 OAG14122.1 - 1.9e-130 435.8 0.0 2.6e-130 435.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family ORC5_C PF14630.6 OAG14123.1 - 4.3e-57 193.8 0.2 6.1e-57 193.3 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAG14123.1 - 2.6e-15 57.2 0.2 7.2e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG14123.1 - 0.0024 18.2 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG14124.1 - 1.5e-09 38.0 1.0 2.9e-09 37.0 0.0 2.0 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 OAG14124.1 - 2.3e-05 24.7 0.0 7.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF668 PF05003.12 OAG14124.1 - 0.032 14.7 0.5 2.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF668) AAA_30 PF13604.6 OAG14124.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rx_N PF18052.1 OAG14124.1 - 0.41 11.0 3.9 4.6 7.6 0.4 3.5 2 1 1 3 3 3 0 Rx N-terminal domain MFS_1 PF07690.16 OAG14126.1 - 4.3e-24 85.1 45.3 8.9e-24 84.1 45.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG14126.1 - 3.7e-20 71.9 26.6 5.3e-20 71.4 26.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG14126.1 - 1.6e-05 24.0 8.7 1.6e-05 24.0 8.7 3.4 2 2 1 4 4 4 2 Sugar (and other) transporter dCMP_cyt_deam_1 PF00383.23 OAG14127.1 - 2.9e-08 33.5 0.2 6.9e-07 29.1 0.2 2.5 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG14127.1 - 0.0034 17.1 0.0 0.018 14.8 0.2 2.0 2 0 0 2 2 2 1 MafB19-like deaminase Cyclase PF04199.13 OAG14130.1 - 8.2e-15 55.2 0.0 2.5e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 OAG14131.1 - 3e-31 108.6 45.0 9.2e-30 103.7 24.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily EcKinase PF02958.20 OAG14132.1 - 1.7e-09 37.5 0.0 7.3e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAG14132.1 - 2.1e-06 27.9 0.2 1.1e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG14132.1 - 0.063 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG14132.1 - 0.18 10.6 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 OAG14133.1 - 7.9e-33 113.9 0.0 7.2e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14133.1 - 1.8e-19 70.1 0.0 2.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG14133.1 - 0.0056 16.1 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 OAG14134.1 - 4.6e-64 216.9 0.0 5.6e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAF-AH_p_II PF03403.13 OAG14135.1 - 0.00084 18.0 0.0 0.038 12.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG14135.1 - 0.0053 15.7 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG14135.1 - 0.0083 15.4 0.0 5.4 6.2 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 MpPF26 PF07666.11 OAG14138.1 - 0.15 12.2 5.6 0.22 11.6 5.6 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 DPM2 PF07297.12 OAG14138.1 - 0.4 11.0 4.4 1.2 9.4 0.1 2.4 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RNase_H PF00075.24 OAG14139.1 - 1.5e-33 115.9 0.0 2.3e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 OAG14139.1 - 6.2e-20 71.2 2.1 1.2e-19 70.3 2.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin COX6B PF02297.17 OAG14139.1 - 0.12 12.6 0.4 0.25 11.6 0.4 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Arm-DNA-bind_4 PF14657.6 OAG14139.1 - 0.99 9.2 3.7 2.5 7.9 0.7 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain DUF202 PF02656.15 OAG14140.1 - 0.0048 17.3 6.9 0.015 15.8 6.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) 6PF2K PF01591.18 OAG14141.1 - 1.3e-73 247.0 0.2 5.5e-52 176.3 0.1 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG14141.1 - 2.9e-30 105.4 0.0 5.8e-22 78.3 0.0 2.9 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG14141.1 - 0.014 15.6 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OAG14141.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CEND1 PF15677.5 OAG14141.1 - 2.6 8.6 11.2 0.079 13.5 3.9 2.2 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 TRAPPC9-Trs120 PF08626.11 OAG14142.1 - 0 1474.5 0.0 0 1474.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF11 PF01345.18 OAG14142.1 - 0.056 13.7 0.2 0.27 11.5 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF11 DUF3684 PF12449.8 OAG14143.1 - 0 1188.6 0.0 0 1188.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 OAG14143.1 - 0.0015 18.3 0.0 0.0049 16.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 OAG14143.1 - 0.028 14.5 0.2 0.028 14.5 0.2 1.9 2 0 0 2 2 2 0 WLM domain GFO_IDH_MocA PF01408.22 OAG14145.1 - 1.3e-25 90.6 0.0 2.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG14145.1 - 3.9e-06 27.5 0.0 6.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG14145.1 - 0.0011 19.2 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG14145.1 - 0.13 12.4 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus G6PD_N PF00479.22 OAG14145.1 - 0.21 12.2 0.0 0.36 11.5 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Mito_carr PF00153.27 OAG14146.1 - 4.7e-52 173.9 4.2 2e-16 59.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 OAG14146.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Transp_cyt_pur PF02133.15 OAG14147.1 - 4.3e-28 98.3 35.0 1.3e-27 96.6 35.0 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 OAG14148.1 - 3.4e-42 144.6 25.6 3.4e-42 144.6 25.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14148.1 - 4.6e-08 32.4 10.8 4.6e-08 32.4 10.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG14148.1 - 0.0097 14.8 0.5 0.0097 14.8 0.5 2.9 1 1 0 2 2 2 1 MFS_1 like family F-box-like PF12937.7 OAG14149.1 - 7.3e-06 25.8 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 OAG14150.1 - 4.7e-06 26.4 0.3 2.1e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 F-box-like DUF1699 PF08004.11 OAG14150.1 - 0.053 13.2 0.7 3.2 7.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Abp2 PF09441.10 OAG14151.1 - 2.3e-83 278.4 0.0 3.5e-83 277.8 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 DUF5572 PF17733.1 OAG14152.1 - 5.5e-24 83.7 2.9 1e-23 82.9 2.9 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 OAG14153.1 - 2.4e-31 107.7 0.1 2.8e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 OAG14153.1 - 7.7e-07 29.2 0.0 9e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 OAG14153.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain FDF PF09532.10 OAG14154.1 - 2.9e-21 76.3 1.1 2.9e-21 76.3 1.1 2.2 3 1 0 3 3 3 1 FDF domain GRP PF07172.11 OAG14154.1 - 0.03 15.0 20.3 0.3 11.8 12.8 2.5 2 0 0 2 2 2 0 Glycine rich protein family TFIIA PF03153.13 OAG14154.1 - 0.57 10.1 22.4 0.84 9.6 22.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit API5 PF05918.11 OAG14154.1 - 1.8 7.3 17.4 0.75 8.5 2.9 2.2 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) F-box-like PF12937.7 OAG14155.1 - 5.1e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG14155.1 - 0.094 12.6 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain Peptidase_M35 PF02102.15 OAG14157.1 - 2.9e-79 266.6 12.7 3.2e-79 266.4 12.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 OAG14157.1 - 1e-35 123.4 3.8 1.5e-35 122.8 3.8 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase F-box-like PF12937.7 OAG14158.1 - 6.9e-06 25.9 0.1 2.2e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 OAG14159.1 - 1.1e-12 48.3 0.1 0.00012 22.6 0.0 4.0 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG14159.1 - 6.5e-10 38.4 0.0 0.3 11.8 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OAG14159.1 - 4.8e-09 36.3 0.2 0.58 10.5 0.0 5.8 4 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG14159.1 - 1.3e-06 28.8 0.1 0.02 15.5 0.0 4.5 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG14159.1 - 0.00032 21.0 0.1 1.2 9.8 0.0 4.5 3 1 0 3 3 3 1 Ankyrin repeat BTB PF00651.31 OAG14164.1 - 5.9e-07 29.7 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Lys-AminoMut_A PF09043.11 OAG14164.1 - 0.019 13.4 0.1 0.026 13.0 0.1 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RRP36 PF06102.12 OAG14166.1 - 2.5e-53 180.4 32.1 2.5e-53 180.4 32.1 2.4 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 NIF PF03031.18 OAG14167.1 - 1.1e-20 74.0 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LPD1 PF18796.1 OAG14167.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 1 Thioredox_DsbH PF03190.15 OAG14169.1 - 1.7e-73 246.0 0.0 2.8e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 OAG14169.1 - 3.9e-09 36.6 0.0 7.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 OAG14169.1 - 0.00022 20.8 0.1 0.00038 20.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sigma70_r3 PF04539.16 OAG14169.1 - 0.016 15.3 0.4 0.06 13.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-70 region 3 Glyco_hydro_76 PF03663.14 OAG14169.1 - 0.058 12.9 0.3 0.14 11.6 0.2 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG14169.1 - 0.082 12.0 0.0 9 5.3 0.0 2.6 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Mrr_N PF14338.6 OAG14169.1 - 0.097 12.8 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 Mrr N-terminal domain CAP PF00188.26 OAG14170.1 - 4.5e-17 63.0 0.6 6.1e-17 62.6 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LRR_4 PF12799.7 OAG14171.1 - 1.7 9.2 12.5 2.5 8.6 0.3 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) PUF PF00806.19 OAG14172.1 - 6.5e-60 195.6 5.8 9.1e-08 31.4 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 OAG14172.1 - 0.11 12.4 0.9 17 5.3 0.0 3.7 4 1 1 5 5 5 0 Single Cache domain 2 TBPIP PF07106.13 OAG14172.1 - 0.69 9.9 3.3 3.8 7.5 0.0 3.4 3 1 1 4 4 4 0 TBPIP/Hop2 winged helix domain MgtE_N PF03448.17 OAG14172.1 - 1.7 9.3 5.8 36 5.0 0.0 3.4 4 0 0 4 4 4 0 MgtE intracellular N domain CopD PF05425.13 OAG14174.1 - 0.0075 16.7 0.1 0.0097 16.3 0.1 1.2 1 0 0 1 1 1 1 Copper resistance protein D NnrU PF07298.11 OAG14174.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 NnrU protein ISK_Channel PF02060.15 OAG14174.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Phosphodiest PF01663.22 OAG14175.1 - 1.6e-13 51.0 0.2 2.8e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAG14175.1 - 0.00035 20.0 0.5 0.00059 19.3 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OAG14175.1 - 0.0016 17.9 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 OAG14175.1 - 0.057 13.5 0.2 9.7 6.2 0.0 2.3 2 0 0 2 2 2 0 PglZ domain Dynamitin PF04912.14 OAG14176.1 - 0.44 9.8 2.0 1.8 7.8 2.0 1.9 1 1 0 1 1 1 0 Dynamitin MJ1316 PF04457.12 OAG14177.1 - 0.28 11.9 2.9 1 10.2 0.1 3.0 3 0 0 3 3 3 0 MJ1316 RNA cyclic group end recognition domain Phage_TAC_1 PF06222.11 OAG14181.1 - 0.019 14.7 0.4 0.049 13.4 0.4 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone CT_C_D PF02682.16 OAG14181.1 - 0.11 12.3 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF2457 PF10446.9 OAG14181.1 - 2.2 7.3 12.7 2.9 6.9 11.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) zf-Di19 PF05605.12 OAG14183.1 - 0.073 13.4 2.1 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OAG14183.1 - 0.1 13.5 1.7 0.64 11.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger RAP1 PF07218.11 OAG14183.1 - 1.7 6.8 3.2 2.2 6.5 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) VTC PF09359.10 OAG14184.1 - 1.1e-90 303.8 1.0 1.4e-90 303.4 0.2 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 OAG14184.1 - 5.2e-13 49.2 2.2 1.2e-12 48.1 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 OAG14184.1 - 2.5e-07 31.0 23.7 1.2e-05 25.4 1.2 3.9 2 1 2 4 4 4 2 SPX domain Vps52 PF04129.12 OAG14184.1 - 0.062 12.0 0.7 0.11 11.2 0.7 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family Receptor_2B4 PF11465.8 OAG14184.1 - 0.25 11.6 1.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Peptidase_S41 PF03572.18 OAG14185.1 - 1.4e-07 31.2 0.0 8.8e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S41 GFA PF04828.14 OAG14186.1 - 0.0039 17.5 0.4 0.0065 16.8 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme 3Beta_HSD PF01073.19 OAG14187.1 - 1.1e-48 165.7 0.1 1.4e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG14187.1 - 1.4e-29 103.3 0.2 1.7e-29 103.0 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG14187.1 - 5.3e-17 61.8 0.7 2.4e-13 49.9 0.3 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG14187.1 - 1.4e-15 57.6 0.9 2.7e-15 56.6 0.3 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG14187.1 - 1.9e-12 46.9 0.1 2.3e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG14187.1 - 8.3e-07 28.4 0.3 1.8e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG14187.1 - 0.00085 19.6 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG14187.1 - 0.016 15.1 0.4 0.47 10.3 0.4 2.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 OAG14187.1 - 0.039 13.5 0.2 0.084 12.4 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family TrkA_N PF02254.18 OAG14187.1 - 0.045 14.0 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3678 PF12435.8 OAG14187.1 - 0.049 13.0 0.7 0.16 11.4 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SpoU_sub_bind PF08032.12 OAG14187.1 - 0.059 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding GFO_IDH_MocA PF01408.22 OAG14187.1 - 0.076 13.8 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HET PF06985.11 OAG14189.1 - 8.2e-33 113.8 0.0 1.5e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ASXH PF13919.6 OAG14191.1 - 2.8e-24 85.7 0.1 5.3e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 OAG14192.1 - 8.2e-27 93.1 0.4 1.6e-26 92.2 0.4 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAG14192.1 - 2.4e-15 56.1 0.6 8.7e-15 54.3 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 OAG14192.1 - 0.02 14.8 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein SLM4 DUF4763 PF15960.5 OAG14192.1 - 0.044 13.1 0.7 0.51 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Abhydrolase_6 PF12697.7 OAG14193.1 - 2.6e-20 74.0 0.3 3.2e-20 73.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG14193.1 - 0.05 13.2 0.6 9.1 5.8 0.3 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14193.1 - 0.059 12.6 0.0 0.92 8.7 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 HlyD_D4 PF16572.5 OAG14193.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB HAD_2 PF13419.6 OAG14194.1 - 0.0017 18.4 0.0 0.006 16.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG14194.1 - 0.0079 16.5 0.0 0.017 15.5 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Toprim PF01751.22 OAG14194.1 - 0.06 13.6 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Toprim domain Pkinase PF00069.25 OAG14195.1 - 1.8e-55 188.2 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14195.1 - 1.2e-32 113.2 0.0 1.7e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG14195.1 - 3.5e-12 46.3 0.0 3e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OAG14195.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG14195.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DAO PF01266.24 OAG14196.1 - 4e-31 108.9 0.1 5.7e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG14196.1 - 0.0047 17.1 0.1 0.019 15.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG14196.1 - 0.038 14.0 4.5 0.083 12.9 0.0 2.7 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG14196.1 - 0.053 12.7 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4126 PF13548.6 OAG14196.1 - 0.45 10.2 1.6 12 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4126) Med6 PF04934.14 OAG14197.1 - 1.9e-12 47.1 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.9 OAG14198.1 - 2.3e-32 111.1 4.5 2.3e-32 111.1 4.5 3.1 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Amidase PF01425.21 OAG14199.1 - 1.6e-79 268.0 0.0 2.8e-79 267.2 0.0 1.4 1 1 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 OAG14200.1 - 6.8e-22 78.2 0.0 6.3e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain U1snRNP70_N PF12220.8 OAG14201.1 - 0.019 15.6 6.3 0.38 11.4 0.1 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HalX PF08663.10 OAG14201.1 - 0.71 10.2 5.7 0.35 11.2 0.2 2.8 3 0 0 3 3 3 0 HalX domain Peptidase_S49_N PF08496.10 OAG14201.1 - 1.1 9.3 3.2 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PHD PF00628.29 OAG14202.1 - 2.1e-07 30.7 8.8 3.6e-07 30.0 8.8 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 OAG14202.1 - 0.00012 22.6 0.9 0.0003 21.3 0.0 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 OAG14202.1 - 0.19 12.0 1.7 0.46 10.8 1.7 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain SpoIIIAH PF12685.7 OAG14202.1 - 0.51 10.1 7.1 0.47 10.3 0.1 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein MFS_1 PF07690.16 OAG14203.1 - 5.2e-45 153.9 40.8 5.2e-45 153.9 40.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily S10_plectin PF03501.15 OAG14203.1 - 0.044 13.9 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 Plectin/S10 domain OATP PF03137.20 OAG14203.1 - 0.072 11.4 3.4 0.21 9.8 3.4 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PhoH PF02562.16 OAG14204.1 - 0.016 14.7 0.1 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 OAG14204.1 - 0.034 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Pescadillo_N PF06732.11 OAG14204.1 - 0.05 13.2 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Pescadillo N-terminus NACHT PF05729.12 OAG14204.1 - 0.065 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain HET PF06985.11 OAG14206.1 - 7.8e-15 55.5 3.0 1e-11 45.4 0.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG14206.1 - 1.3e-11 44.7 0.1 2.3e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 OAG14206.1 - 4.4e-09 36.8 0.1 2.6e-08 34.3 0.1 2.4 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG14206.1 - 2.3e-06 27.8 1.5 0.0038 17.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAG14206.1 - 2.6e-06 27.9 0.0 2e-05 25.0 0.0 2.7 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG14206.1 - 2.6e-06 27.3 0.0 0.027 15.0 0.0 4.0 3 0 0 3 3 2 2 Ankyrin repeat AAA_16 PF13191.6 OAG14206.1 - 3.7e-05 24.2 0.8 0.00021 21.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG14206.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.6 OAG14206.1 - 0.00011 22.4 0.0 0.00035 20.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf_C2H2_13 PF18508.1 OAG14206.1 - 0.0038 16.8 0.1 0.0093 15.5 0.1 1.7 1 0 0 1 1 1 1 Zinc finger domain AAA PF00004.29 OAG14206.1 - 0.0045 17.4 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAG14206.1 - 0.0054 16.0 0.1 0.012 14.8 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAG14206.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OAG14206.1 - 0.019 15.0 0.0 0.089 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 OAG14206.1 - 0.056 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Torsin CDC50 PF03381.15 OAG14207.1 - 2e-99 332.7 0.0 2.4e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 OAG14207.1 - 3.6 7.7 5.5 1.2 9.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SWIRM PF04433.17 OAG14208.1 - 1.1e-12 48.0 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain p450 PF00067.22 OAG14210.1 - 8e-41 140.2 0.1 9.5e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CENP-I PF07778.11 OAG14211.1 - 4.8e-44 150.9 0.0 5.3e-43 147.5 0.0 2.0 1 1 0 1 1 1 1 Mis6 SPT_ssu-like PF11779.8 OAG14213.1 - 1.2e-23 82.5 5.2 1.2e-23 82.5 5.2 1.9 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like FtsX PF02687.21 OAG14213.1 - 0.32 11.5 6.2 0.59 10.6 6.2 1.4 1 1 0 1 1 1 0 FtsX-like permease family RF-1 PF00472.20 OAG14214.1 - 2.9e-25 88.5 1.8 4.6e-25 87.8 1.8 1.2 1 0 0 1 1 1 1 RF-1 domain FAD_binding_4 PF01565.23 OAG14215.1 - 5.6e-23 81.2 5.6 1.3e-22 80.0 5.6 1.7 1 0 0 1 1 1 1 FAD binding domain Chitin_bind_1 PF00187.19 OAG14215.1 - 3.1e-12 46.7 50.5 4.1e-06 27.2 23.1 3.2 2 1 0 2 2 2 2 Chitin recognition protein BBE PF08031.12 OAG14215.1 - 9.5e-10 38.4 0.1 1.6e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like SKG6 PF08693.10 OAG14217.1 - 0.16 11.4 0.2 0.16 11.4 0.2 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 OAG14217.1 - 0.24 11.6 1.7 0.24 11.6 0.2 1.9 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Gly_transf_sug PF04488.15 OAG14218.1 - 6.4e-12 45.9 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OAG14218.1 - 7e-06 25.6 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Zn_clus PF00172.18 OAG14219.1 - 9e-11 41.7 10.7 1.3e-10 41.2 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD PF01966.22 OAG14221.1 - 9.4e-06 25.9 1.3 9.4e-06 25.9 1.3 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 OAG14221.1 - 0.0029 17.4 0.4 0.0059 16.4 0.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pex16 PF08610.10 OAG14222.1 - 4.4e-141 469.7 0.2 5e-141 469.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) MitMem_reg PF13012.6 OAG14223.1 - 8.7e-38 129.2 0.0 1.5e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG14223.1 - 1.9e-30 105.2 0.0 3.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 OAG14223.1 - 0.18 11.5 2.6 0.26 11.0 2.6 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 OAG14223.1 - 0.59 9.8 1.2 0.89 9.3 1.2 1.2 1 0 0 1 1 1 0 Connexin SWIM PF04434.17 OAG14224.1 - 0.019 14.6 0.2 0.019 14.6 0.2 2.3 2 0 0 2 2 2 0 SWIM zinc finger Mito_carr PF00153.27 OAG14227.1 - 3.4e-66 219.2 5.8 4e-24 84.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 OAG14227.1 - 0.031 14.0 0.8 0.1 12.3 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Pec_lyase_C PF00544.19 OAG14230.1 - 1.4e-39 135.9 8.8 1.9e-39 135.4 8.8 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG14230.1 - 0.00012 22.0 8.2 0.0003 20.7 8.2 1.6 1 1 0 1 1 1 1 Right handed beta helix region F-box-like PF12937.7 OAG14232.1 - 0.034 14.0 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like Malt_amylase_C PF16657.5 OAG14232.1 - 0.18 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain HET PF06985.11 OAG14233.1 - 5.9e-27 94.8 0.0 1.1e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_rhamnosid6H PF17389.2 OAG14234.1 - 8.4e-12 45.0 0.0 4.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 OAG14234.1 - 1.1e-09 38.0 0.3 6e-09 35.6 0.1 2.3 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase C-terminal domain Laminin_G_3 PF13385.6 OAG14234.1 - 0.084 13.0 1.4 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily ERG4_ERG24 PF01222.17 OAG14235.1 - 2.4e-131 438.4 19.4 2.8e-131 438.2 19.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4131 PF13567.6 OAG14235.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) Glyco_hydro_17 PF00332.18 OAG14236.1 - 3.2e-07 30.3 4.7 6.2e-07 29.3 4.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Chitin_bind_1 PF00187.19 OAG14236.1 - 1.9e-06 28.2 26.2 3.3e-06 27.5 26.2 1.4 1 0 0 1 1 1 1 Chitin recognition protein ParG PF09274.10 OAG14236.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 ParG WXG100 PF06013.12 OAG14236.1 - 0.24 11.7 1.8 0.23 11.7 0.3 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Proteasome PF00227.26 OAG14237.1 - 3.2e-54 183.3 0.0 4.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG14237.1 - 1.9e-12 46.6 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature QCR10 PF09796.9 OAG14238.1 - 3.3e-29 100.7 0.7 3.7e-29 100.6 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-CCHC PF00098.23 OAG14239.1 - 1.8e-06 27.8 2.5 2.6e-06 27.2 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle MPP6 PF10175.9 OAG14239.1 - 2.3e-05 24.9 12.7 0.0003 21.3 12.1 2.3 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CCHC_3 PF13917.6 OAG14239.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle SabA_adhesion PF18304.1 OAG14239.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain PNISR PF15996.5 OAG14239.1 - 1 9.6 11.3 1.6 8.9 11.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RXT2_N PF08595.11 OAG14239.1 - 4.9 7.2 11.7 2.6e+02 1.6 11.6 2.2 1 1 0 1 1 1 0 RXT2-like, N-terminal EthD PF07110.11 OAG14240.1 - 1.4e-19 71.0 0.5 1.8e-19 70.7 0.5 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG14240.1 - 0.005 17.3 0.2 0.0076 16.7 0.2 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Benyvirus_P25 PF05744.11 OAG14240.1 - 0.0069 15.7 0.2 0.0086 15.4 0.2 1.1 1 0 0 1 1 1 1 Benyvirus P25/P26 protein Peptidase_M16_M PF16187.5 OAG14241.1 - 3.9e-94 315.1 0.2 6.9e-94 314.2 0.2 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OAG14241.1 - 4.2e-31 107.9 5.0 8.6e-31 106.9 0.7 3.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG14241.1 - 2.7e-30 105.7 1.7 1.9e-20 73.7 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Styelin PF17562.2 OAG14241.1 - 0.12 12.7 0.3 29 5.1 0.0 3.9 4 0 0 4 4 4 0 Styelin FLILHELTA PF10306.9 OAG14243.1 - 3.2e-33 114.0 3.0 7.5e-33 112.8 0.1 2.6 3 0 0 3 3 3 1 Hypothetical protein FLILHELTA DUF2079 PF09852.9 OAG14243.1 - 0.068 12.0 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) UPF0047 PF01894.17 OAG14245.1 - 1.6e-37 128.1 0.0 2.4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Sigma_reg_N PF13800.6 OAG14245.1 - 0.044 14.1 0.3 0.076 13.3 0.3 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-CHCC PF10276.9 OAG14246.1 - 4.1e-16 58.7 2.1 6.7e-16 58.1 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain AAL_decarboxy PF03306.13 OAG14247.1 - 1.2e-31 109.8 0.0 1.6e-15 57.1 0.0 2.0 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase Glyco_transf_90 PF05686.12 OAG14248.1 - 1.8e-27 96.3 0.2 2.4e-27 95.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG14248.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.16 OAG14249.1 - 2.2e-13 49.9 19.9 2.2e-13 49.9 19.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG14249.1 - 2.4e-05 24.1 2.9 2.4e-05 24.1 2.9 2.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Peptidase_M18 PF02127.15 OAG14250.1 - 3.2e-131 438.1 0.0 3.8e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) IPP-2 PF04979.14 OAG14251.1 - 1.1e-23 84.5 15.5 2.1e-23 83.5 15.5 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF1179 PF06678.11 OAG14251.1 - 0.55 10.2 4.2 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) IF4E PF01652.18 OAG14252.1 - 4.5e-53 179.3 0.2 6.3e-53 178.8 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 OAG14253.1 - 8.7e-27 94.4 0.0 2.1e-26 93.1 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GGACT PF06094.12 OAG14254.1 - 2.7e-17 63.5 0.0 4.7e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like PQ-loop PF04193.14 OAG14255.1 - 2.4e-20 72.1 0.8 1.5e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAG14255.1 - 0.00096 20.0 2.4 0.0014 19.5 2.4 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor GP41 PF00517.17 OAG14256.1 - 0.031 14.2 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Glyco_hydro_43 PF04616.14 OAG14257.1 - 1.7e-67 227.8 13.2 4.4e-59 200.2 2.4 2.9 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG14257.1 - 5.6e-09 36.0 0.9 0.0011 18.7 0.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Lipoprotein_15 PF03640.15 OAG14257.1 - 0.1 12.2 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Secreted repeat of unknown function Alk_phosphatase PF00245.20 OAG14258.1 - 6.4e-77 259.2 0.0 7.8e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase GCP_N_terminal PF17681.1 OAG14260.1 - 9.2e-36 124.0 0.0 1.9e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG14260.1 - 2.6e-19 69.9 0.3 7e-19 68.4 0.3 1.8 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 OAG14260.1 - 0.042 12.2 0.1 0.45 8.8 0.0 2.3 3 0 0 3 3 3 0 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 OAG14261.1 - 1.3e-113 379.5 8.4 1.6e-113 379.2 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.25 OAG14262.1 - 1.4e-26 93.5 0.0 2.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 OAG14262.1 - 5.4e-23 82.0 0.0 1.4e-22 80.6 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 OAG14262.1 - 3.9e-12 46.0 0.0 7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG14264.1 - 2.9e-18 66.2 0.0 1e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14264.1 - 3.4e-12 46.2 0.0 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase OCD_Mu_crystall PF02423.15 OAG14265.1 - 3e-17 62.6 0.0 6.5e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG14265.1 - 7.9e-10 38.9 0.0 6.6e-09 35.9 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Staph_opine_DH PF10100.9 OAG14265.1 - 0.034 12.8 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG14265.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OAG14265.1 - 0.1 12.1 0.1 20 4.6 0.0 2.6 3 0 0 3 3 3 0 NmrA-like family DAO PF01266.24 OAG14266.1 - 8.6e-33 114.4 0.2 9.7e-33 114.2 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG14266.1 - 0.00015 21.9 0.0 0.00039 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG14266.1 - 0.00019 21.9 0.3 0.0022 18.5 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG14266.1 - 0.00019 20.6 0.1 0.00035 19.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG14266.1 - 0.00046 19.5 0.0 0.001 18.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG14266.1 - 0.00093 18.9 0.6 0.00093 18.9 0.6 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAG14266.1 - 0.0094 15.2 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG14266.1 - 0.0097 15.2 0.7 0.09 12.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 OAG14266.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAG14266.1 - 0.039 13.2 0.1 0.063 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 OAG14266.1 - 0.11 12.4 0.3 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GATase_5 PF13507.6 OAG14267.1 - 4.7e-101 337.3 0.0 6.9e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAG14267.1 - 2.5e-41 141.4 0.2 7e-26 91.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAG14267.1 - 1.1e-32 112.4 0.0 2.1e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAG14267.1 - 1.9e-21 76.3 0.2 1.5e-20 73.5 0.1 2.4 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF4959 PF16323.5 OAG14268.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4959) DAO PF01266.24 OAG14269.1 - 2.1e-32 113.1 0.7 2.7e-32 112.7 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG14269.1 - 0.0036 17.5 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG14269.1 - 0.004 17.2 0.1 0.012 15.6 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG14269.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG14270.1 - 2.9e-32 112.0 65.4 1.1e-30 106.8 63.7 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14270.1 - 1.9e-12 46.8 9.9 1.9e-12 46.8 9.9 3.4 3 1 2 5 5 5 1 Sugar (and other) transporter Fungal_trans PF04082.18 OAG14271.1 - 2.9e-09 36.4 0.2 4.7e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14271.1 - 7.1e-08 32.5 9.4 7.1e-08 32.5 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1929 PF09118.11 OAG14272.1 - 8.5e-25 86.9 0.0 2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.26 OAG14272.1 - 1.9e-14 53.4 5.1 4.3e-07 29.8 0.1 2.4 1 1 0 2 2 2 2 PAN domain Kelch_6 PF13964.6 OAG14272.1 - 1.1e-13 51.0 5.6 0.00023 21.3 0.1 5.2 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OAG14272.1 - 1.2e-12 47.3 0.0 4.9e-06 26.3 0.0 5.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 OAG14272.1 - 3.9e-11 42.4 0.2 3e-06 26.7 0.1 4.5 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 OAG14272.1 - 5.3e-09 36.0 7.0 0.0025 17.8 0.2 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG14272.1 - 1.1e-05 25.6 0.2 1.3 9.4 0.0 4.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 OAG14272.1 - 7.6e-05 22.0 0.0 0.11 11.6 0.0 2.5 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus PAN_3 PF08277.12 OAG14272.1 - 0.00098 18.9 5.2 0.18 11.6 0.4 2.5 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.14 OAG14272.1 - 0.24 11.7 4.3 3.4 8.0 0.2 2.4 2 0 0 2 2 2 0 MANEC domain PAN_4 PF14295.6 OAG14272.1 - 3.3 7.7 16.9 3 7.8 0.9 3.1 2 1 1 3 3 3 0 PAN domain zf-C3HC4_3 PF13920.6 OAG14273.1 - 0.022 14.6 1.4 0.022 14.6 1.4 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NUDIX_2 PF13869.6 OAG14274.1 - 3.5e-79 264.8 0.0 4.2e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RmlD_sub_bind PF04321.17 OAG14275.1 - 6.1e-51 173.2 0.0 7.7e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAG14275.1 - 2.7e-21 76.2 0.0 3.3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG14275.1 - 1.3e-10 41.2 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG14275.1 - 5.3e-09 35.6 0.0 5.5e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 OAG14275.1 - 3.1e-08 33.1 0.2 2.5e-06 26.8 0.0 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG14275.1 - 7.2e-08 31.8 0.0 2.9e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3433 PF11915.8 OAG14276.1 - 8.6e-37 125.5 19.5 1.3e-21 76.8 1.5 3.5 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Glyco_hydro_61 PF03443.14 OAG14277.1 - 0.00041 20.4 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Metallophos PF00149.28 OAG14278.1 - 2.1e-37 129.6 0.1 4.1e-37 128.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4032 PF13224.6 OAG14279.1 - 0.033 14.1 0.9 0.078 12.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) SAM_decarbox PF01536.16 OAG14281.1 - 1.2e-131 439.0 0.0 2.2e-131 438.1 0.0 1.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase EHN PF06441.12 OAG14282.1 - 4e-32 110.8 0.1 7.5e-32 109.9 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG14282.1 - 7e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hid1 PF12722.7 OAG14283.1 - 0 1083.5 0.0 0 1083.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAG14283.1 - 2.4e-113 379.7 0.0 3e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein INTAP PF16617.5 OAG14283.1 - 0.034 14.5 1.2 0.07 13.5 1.2 1.5 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region DUF2486 PF10667.9 OAG14283.1 - 0.062 13.5 2.0 0.11 12.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) ERCC3_RAD25_C PF16203.5 OAG14284.1 - 2.5e-120 400.3 0.8 4.2e-120 399.5 0.8 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAG14284.1 - 1.4e-31 109.3 0.2 1.5e-30 105.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG14284.1 - 9e-16 58.3 0.0 2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG14284.1 - 2.5e-13 50.3 0.4 8.2e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAG14284.1 - 3.5e-06 26.0 0.0 5.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.6 OAG14284.1 - 0.03 13.7 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Dehydratase_hem PF13816.6 OAG14285.1 - 7.7e-96 321.1 0.1 8.8e-96 320.9 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 OAG14285.1 - 9.2e-07 29.2 0.7 0.017 15.5 0.1 2.9 2 2 0 2 2 2 2 Domain of unknown function (DUF4188) MFS_1 PF07690.16 OAG14286.1 - 8.3e-32 110.5 21.6 8.3e-32 110.5 21.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG14286.1 - 0.0024 16.2 2.2 0.017 13.4 2.2 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Bap31_Bap29_C PF18035.1 OAG14286.1 - 0.088 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Phage_holin_3_7 PF05449.11 OAG14286.1 - 1.1 9.4 4.9 1 9.4 0.5 2.9 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 MatE PF01554.18 OAG14287.1 - 2.4e-62 209.4 26.1 3.2e-36 124.4 10.5 2.3 2 0 0 2 2 2 2 MatE Pex2_Pex12 PF04757.14 OAG14287.1 - 1.5e-51 175.1 0.3 1.5e-51 175.1 0.3 1.6 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region Polysacc_synt_C PF14667.6 OAG14287.1 - 4e-05 23.7 8.5 4e-05 23.7 8.5 3.9 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain zf-C3HC4_4 PF15227.6 OAG14287.1 - 0.0046 17.1 0.6 0.0083 16.3 0.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG14287.1 - 0.021 14.6 0.4 0.039 13.8 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG14287.1 - 0.026 14.4 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG14287.1 - 0.031 14.1 0.3 0.052 13.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG14287.1 - 0.089 12.8 1.6 0.17 11.9 1.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Peptidase_M28 PF04389.17 OAG14288.1 - 1.3e-36 126.2 0.0 2.1e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PQ-loop PF04193.14 OAG14288.1 - 6.2e-23 80.3 15.9 1.2e-11 44.2 0.6 3.6 3 0 0 3 3 3 2 PQ loop repeat PA PF02225.22 OAG14288.1 - 1.8e-11 43.9 0.1 4.1e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG14288.1 - 6.6e-05 22.7 0.0 0.00019 21.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OAG14288.1 - 0.085 11.9 0.0 0.21 10.6 0.0 1.6 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase DUF2070 PF09843.9 OAG14288.1 - 0.85 7.8 3.9 1.5 7.1 3.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Caleosin PF05042.13 OAG14289.1 - 7.4e-65 218.0 0.1 1.1e-64 217.5 0.1 1.2 1 0 0 1 1 1 1 Caleosin related protein GCP_N_terminal PF17681.1 OAG14290.1 - 3.8e-34 118.7 0.6 7.1e-34 117.8 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG14290.1 - 1.7e-23 83.5 0.1 3e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal PapG_N PF03627.13 OAG14290.1 - 0.039 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 PapG carbohydrate binding domain DUF429 PF04250.13 OAG14290.1 - 0.076 12.8 0.1 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF429) PIN_8 PF18476.1 OAG14290.1 - 0.088 12.6 0.5 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 PIN like domain TetR_C_36 PF18598.1 OAG14290.1 - 0.15 12.1 0.5 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain BTB_2 PF02214.22 OAG14292.1 - 1.6e-09 38.0 0.0 4.4e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG14292.1 - 0.00022 21.4 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Auxin_inducible PF02519.14 OAG14292.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Auxin responsive protein DUF3444 PF11926.8 OAG14293.1 - 0.078 12.6 0.3 0.12 12.0 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3444) Polyketide_cyc PF03364.20 OAG14293.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport F1F0-ATPsyn_F PF10791.9 OAG14295.1 - 6.3e-41 138.8 0.3 7.1e-41 138.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 OAG14296.1 - 1.3e-34 118.3 2.1 2.2e-34 117.6 2.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Plk4_PB2 PF18409.1 OAG14296.1 - 0.045 14.4 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Lipase_GDSL_2 PF13472.6 OAG14297.1 - 1.1e-10 42.2 0.0 1.6e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG14297.1 - 1.3e-07 31.8 0.0 1.7e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OAG14297.1 - 0.00086 19.5 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 OAG14297.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 OSK domain DUF4553 PF15090.6 OAG14299.1 - 0.64 8.9 10.1 1.1 8.2 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Cwf_Cwc_15 PF04889.12 OAG14300.1 - 0.037 13.8 8.6 0.066 12.9 0.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 OAG14300.1 - 0.087 12.8 0.4 0.087 12.8 0.4 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3246 PF11596.8 OAG14300.1 - 0.13 11.6 1.7 0.12 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 OAG14300.1 - 3.2 8.2 11.0 0.92 9.9 4.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pyridox_oxase_2 PF12766.7 OAG14302.1 - 9.4e-26 90.4 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CDC27 PF09507.10 OAG14303.1 - 6.7e-78 263.0 29.3 7.9e-78 262.7 29.3 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF2870 PF11069.8 OAG14303.1 - 1.1 9.6 5.8 1.2 9.5 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) TerB_C PF15615.6 OAG14303.1 - 7.1 6.9 16.5 2.6 8.3 8.5 2.7 1 1 1 3 3 3 0 TerB-C domain TFCD_C PF12612.8 OAG14304.1 - 1.3e-26 93.6 1.1 1.4e-23 83.7 1.1 2.8 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal IFRD PF05004.13 OAG14304.1 - 6.6e-05 22.2 6.0 0.00082 18.6 0.6 3.3 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 OAG14304.1 - 0.00016 22.0 3.8 0.18 12.2 0.1 4.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OAG14304.1 - 0.0005 20.1 10.0 1.2 9.5 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat Vac14_Fab1_bd PF12755.7 OAG14304.1 - 0.0052 17.3 0.0 0.044 14.4 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 OAG14304.1 - 0.15 12.1 0.9 3.1 8.0 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG14304.1 - 10 6.8 14.8 0.85 10.2 0.0 6.2 7 0 0 7 7 7 0 HEAT-like repeat OTU PF02338.19 OAG14305.1 - 7.5e-14 52.3 0.5 1.2e-13 51.7 0.5 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAG14305.1 - 0.00034 20.1 1.4 0.087 12.3 0.2 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain TRAPPC-Trs85 PF12739.7 OAG14306.1 - 1.7e-113 379.7 0.1 7.8e-113 377.5 0.3 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 OAG14306.1 - 0.4 10.9 1.4 7.6 6.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Tti2 PF10521.9 OAG14307.1 - 1.2e-63 215.3 0.4 2.1e-63 214.5 0.4 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 OAG14307.1 - 3.9e-21 75.8 1.1 5.6e-20 72.0 1.1 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAG14307.1 - 1.6e-08 34.2 0.1 5.4e-08 32.5 0.1 2.0 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 OAG14307.1 - 0.00028 20.9 0.0 0.0026 17.8 0.0 2.4 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative DNA_pol_E_B PF04042.16 OAG14307.1 - 0.095 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF5134 PF17197.4 OAG14308.1 - 2.2 8.2 4.6 1.3 9.0 1.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Npa1 PF11707.8 OAG14309.1 - 2.2e-94 316.6 0.0 3.5e-93 312.7 0.0 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAG14309.1 - 7e-57 192.3 0.1 3e-56 190.2 0.0 2.1 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Glyco_hydro_72 PF03198.14 OAG14312.1 - 2e-107 359.1 4.7 2e-107 359.1 4.7 1.5 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 OAG14312.1 - 1.5e-20 73.6 7.9 4e-20 72.3 7.9 1.8 1 0 0 1 1 1 1 X8 domain bZIP_1 PF00170.21 OAG14313.1 - 9.7e-07 28.8 5.4 9.7e-07 28.8 5.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG14313.1 - 0.034 14.2 8.6 0.034 14.2 8.6 1.6 2 0 0 2 2 2 0 Basic region leucine zipper GCN5L1 PF06320.13 OAG14313.1 - 0.067 13.4 1.4 0.12 12.5 1.4 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) RsfS PF02410.15 OAG14315.1 - 5.8e-15 55.5 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF489 PF04356.12 OAG14315.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Prefoldin PF02996.17 OAG14315.1 - 0.41 10.6 2.2 0.69 9.8 2.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Pex14_N PF04695.13 OAG14315.1 - 3.8 8.1 12.7 2.1 9.0 3.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NMD3 PF04981.13 OAG14316.1 - 2.1e-77 259.9 0.6 3.3e-77 259.2 0.6 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAG14316.1 - 0.52 10.4 6.3 35 4.5 6.3 2.9 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 OAG14316.1 - 0.82 9.7 2.6 28 4.8 0.1 2.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Abhydrolase_6 PF12697.7 OAG14319.1 - 3.7e-12 47.3 6.3 1.2e-10 42.3 6.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG14319.1 - 0.00074 18.9 0.2 0.0078 15.5 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG14319.1 - 0.0043 16.7 0.0 0.028 14.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.16 OAG14320.1 - 7.1e-41 140.3 45.2 2.8e-40 138.3 44.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG14320.1 - 1e-08 34.1 24.2 2e-08 33.1 13.2 2.3 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG14320.1 - 0.001 17.5 1.4 0.001 17.5 1.4 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SNCAIP_SNCA_bd PF16700.5 OAG14321.1 - 0.024 14.3 0.4 0.064 13.0 0.4 1.6 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Glyco_transf_28 PF03033.20 OAG14322.1 - 4.8e-25 88.2 0.0 1.1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG14322.1 - 3.6e-05 22.7 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase CYYR1 PF10873.8 OAG14322.1 - 4.3 7.8 6.6 0.81 10.1 1.7 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Pec_lyase_C PF00544.19 OAG14323.1 - 5.5e-39 133.9 3.3 9.5e-39 133.2 3.3 1.3 1 0 0 1 1 1 1 Pectate lyase Fungal_trans PF04082.18 OAG14325.1 - 8e-11 41.5 0.5 2.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14325.1 - 2.7e-06 27.4 10.5 4.6e-06 26.6 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_A5L PF06193.11 OAG14325.1 - 0.4 10.1 4.7 0.83 9.0 4.7 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like MFS_1 PF07690.16 OAG14326.1 - 9.9e-24 83.9 54.1 1.5e-14 53.7 29.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily PLDc_N PF13396.6 OAG14327.1 - 2.1e-12 46.8 4.5 2.1e-12 46.8 4.5 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Glucos_trans_II PF14264.6 OAG14327.1 - 0.015 14.6 4.9 0.023 14.1 4.9 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF1673 PF07895.11 OAG14327.1 - 0.04 13.6 3.1 0.043 13.5 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) MFS_MOT1 PF16983.5 OAG14327.1 - 0.046 14.1 1.8 0.06 13.7 1.8 1.1 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily Pox_A14 PF05767.12 OAG14327.1 - 0.15 12.3 4.8 0.1 12.8 0.9 2.0 1 1 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-RanBP PF00641.18 OAG14328.1 - 0.0014 17.9 3.6 0.0014 17.9 3.6 5.3 7 0 0 7 7 7 2 Zn-finger in Ran binding protein and others ADK_lid PF05191.14 OAG14328.1 - 0.029 14.3 2.1 0.029 14.3 2.1 3.8 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-RING_10 PF16685.5 OAG14328.1 - 0.036 14.2 5.6 0.036 14.2 5.6 4.0 3 2 1 4 4 4 0 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 OAG14328.1 - 0.38 10.7 35.1 1.7 8.6 6.9 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OAG14328.1 - 0.51 10.6 30.7 1.8 8.8 2.0 3.4 2 1 1 3 3 3 0 FYVE-type zinc finger Lon_C PF05362.13 OAG14329.1 - 2e-64 216.9 0.1 3.9e-64 216.0 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG14329.1 - 3e-27 95.9 0.2 6.4e-27 94.8 0.2 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG14329.1 - 1.1e-23 84.1 0.1 5.9e-23 81.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG14329.1 - 3.6e-08 33.5 0.0 1.6e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAG14329.1 - 6.4e-08 32.5 0.4 6e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OAG14329.1 - 5.6e-06 26.8 0.3 2.8e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 OAG14329.1 - 0.0002 21.2 0.0 0.00062 19.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG14329.1 - 0.00028 21.2 0.0 0.0078 16.5 0.0 3.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG14329.1 - 0.0006 19.6 0.0 0.0032 17.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAG14329.1 - 0.00096 18.9 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OAG14329.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAG14329.1 - 0.0018 17.5 0.0 0.0045 16.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OAG14329.1 - 0.0028 17.8 0.0 0.01 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 OAG14329.1 - 0.011 16.1 0.2 0.51 10.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 OAG14329.1 - 0.012 14.5 0.2 0.51 9.2 0.1 2.3 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.21 OAG14329.1 - 0.023 14.1 0.1 0.057 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OAG14329.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG14329.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OAG14329.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 OAG14329.1 - 0.033 14.6 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAG14329.1 - 0.039 13.9 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OAG14329.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG14329.1 - 0.048 13.4 0.0 0.048 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG14329.1 - 0.048 14.2 0.1 0.16 12.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAG14329.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 OAG14329.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAG14329.1 - 0.13 12.8 0.0 0.13 12.8 0.0 2.8 1 1 1 2 2 1 0 AAA domain AAA_11 PF13086.6 OAG14329.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG14329.1 - 0.16 12.5 0.3 1.1 9.7 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 OAG14329.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAG14329.1 - 0.18 11.0 1.3 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 OAG14329.1 - 0.27 11.1 1.3 0.81 9.6 0.1 2.5 2 1 0 2 2 2 0 NTPase PEMT PF04191.13 OAG14330.1 - 4.9e-60 200.5 9.9 4.1e-36 123.6 1.4 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 OAG14330.1 - 0.003 17.3 0.1 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 OAG14330.1 - 0.04 14.5 0.1 0.25 11.9 0.1 2.2 1 1 0 1 1 1 0 SKICH domain YWFCY PF14293.6 OAG14330.1 - 0.27 11.6 2.0 1.5 9.2 0.2 2.8 3 0 0 3 3 3 0 YWFCY protein Methyltransf_33 PF10017.9 OAG14333.1 - 1e-91 307.3 0.0 1.4e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAG14333.1 - 1.1e-18 67.7 3.5 3e-10 40.1 0.5 2.4 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAG14333.1 - 0.016 15.8 0.7 0.084 13.4 0.5 2.3 1 1 1 2 2 2 0 DinB superfamily Peptidase_M15_2 PF05951.13 OAG14334.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Rhomboid PF01694.22 OAG14336.1 - 3.1e-18 66.2 11.7 5.7e-18 65.4 11.7 1.3 1 0 0 1 1 1 1 Rhomboid family Ammonium_transp PF00909.21 OAG14338.1 - 3e-109 365.3 27.4 3.6e-109 365.1 27.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tweety PF04906.13 OAG14338.1 - 1.5 7.4 3.4 0.46 9.1 0.2 1.7 2 0 0 2 2 2 0 Tweety DUF3810 PF12725.7 OAG14338.1 - 9.1 5.5 7.0 3.2 7.0 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2977 PF11192.8 OAG14341.1 - 0.057 13.5 1.5 0.28 11.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2977) Pkinase PF00069.25 OAG14345.1 - 1.8e-72 243.9 0.0 2.7e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14345.1 - 4.2e-37 127.8 0.0 1.3e-36 126.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG14345.1 - 0.00079 18.8 0.7 1.1 8.6 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OAG14345.1 - 0.0034 17.3 0.1 0.49 10.3 0.0 2.9 1 1 2 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG14345.1 - 0.0091 14.8 0.0 0.025 13.4 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase DUF4611 PF15387.6 OAG14345.1 - 0.98 9.7 4.7 0.3 11.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SET PF00856.28 OAG14346.1 - 2.1e-16 60.8 0.0 3.6e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 SET domain YHS PF04945.13 OAG14346.1 - 1.2 9.2 4.4 2.1 8.5 0.2 2.6 3 0 0 3 3 3 0 YHS domain SGL PF08450.12 OAG14347.1 - 3.8e-25 88.9 0.0 6.7e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG14347.1 - 0.0002 21.5 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 Arylesterase Rep_1B PF17873.1 OAG14347.1 - 0.17 11.8 0.2 0.48 10.4 0.2 1.8 1 0 0 1 1 1 0 Replicase polyprotein 1ab DUF1593 PF07632.11 OAG14348.1 - 9.7e-91 303.8 0.0 1.4e-90 303.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) DUF4407 PF14362.6 OAG14349.1 - 0.004 16.6 30.2 0.028 13.8 4.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4407) DUF4618 PF15397.6 OAG14349.1 - 0.28 10.6 22.9 0.037 13.5 5.9 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 OAG14349.1 - 1.3 9.6 15.4 5 7.7 0.0 4.9 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein NPP1 PF05630.11 OAG14350.1 - 1e-59 202.0 0.0 1.2e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Metallophos PF00149.28 OAG14351.1 - 5.9e-15 56.3 0.3 9.7e-15 55.6 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG14351.1 - 1.2e-07 32.1 0.1 1.1e-05 25.6 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3231 PF11553.8 OAG14352.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) PAT1 PF09770.9 OAG14353.1 - 0.77 8.0 37.2 1.1 7.5 37.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Striatin PF08232.12 OAG14355.1 - 1.5 9.4 10.4 0.12 12.9 5.9 1.4 2 0 0 2 2 2 0 Striatin family HET PF06985.11 OAG14357.1 - 1.5e-22 80.5 0.0 7.6e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG14359.1 - 6.4e-24 85.0 0.9 7.2e-24 84.8 0.9 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tox-SHH PF15652.6 OAG14361.1 - 0.074 14.0 0.7 0.23 12.5 0.7 1.8 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature XLF PF09302.11 OAG14362.1 - 1.6e-43 149.0 0.9 3.2e-43 148.0 0.9 1.5 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component KfrA_N PF11740.8 OAG14362.1 - 4.4 8.0 10.4 0.2 12.3 3.2 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Cactin_mid PF10312.9 OAG14363.1 - 4.9e-58 196.1 4.8 4.9e-58 196.1 4.8 2.0 1 1 1 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAG14363.1 - 1.3e-57 193.1 6.5 2e-57 192.5 6.5 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 OAG14363.1 - 0.039 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Endonuc-BglII PF09195.11 OAG14363.1 - 0.17 11.7 1.0 16 5.3 0.3 2.4 2 0 0 2 2 2 0 Restriction endonuclease BglII Utp13 PF08625.11 OAG14363.1 - 0.17 11.8 1.3 0.38 10.6 1.3 1.6 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DUF1087 PF06465.13 OAG14363.1 - 0.86 9.7 3.9 1.8 8.6 0.4 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) LUC7 PF03194.15 OAG14363.1 - 0.98 9.0 5.4 5.1 6.7 0.7 2.4 2 0 0 2 2 2 0 LUC7 N_terminus Forkhead PF00250.18 OAG14365.1 - 4e-25 87.9 0.1 7.9e-25 86.9 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain Glyco_hydro_28 PF00295.17 OAG14366.1 - 5e-52 177.0 12.2 1.3e-51 175.6 12.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Ribonucleas_3_3 PF14622.6 OAG14367.1 - 2.7e-05 24.3 0.1 5.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like CENP-B_N PF04218.13 OAG14367.1 - 0.0042 16.7 0.0 0.41 10.3 0.0 3.1 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain Ribonuclease_3 PF00636.26 OAG14367.1 - 0.028 15.0 0.1 0.089 13.4 0.1 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Ribonuclease_3 PF00636.26 OAG14368.1 - 1.6e-39 134.8 0.0 7.7e-21 74.7 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG14368.1 - 6.7e-29 100.6 0.0 1.6e-15 57.4 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 OAG14368.1 - 1.5e-24 85.9 0.0 5.1e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 OAG14368.1 - 1.4e-18 67.3 0.0 3.6e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG14368.1 - 2.1e-08 34.1 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCCH PF00642.24 OAG14369.1 - 2.2e-05 24.2 5.8 2.2e-05 24.2 5.8 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG14369.1 - 0.0033 17.4 8.5 0.0033 17.4 8.5 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG14369.1 - 0.11 12.3 6.5 0.083 12.7 4.6 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger DUF3638 PF12340.8 OAG14370.1 - 5.1e-59 199.3 0.6 2.7e-35 121.7 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG14370.1 - 3.5e-18 64.7 0.7 7.1e-18 63.7 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DDE_3 PF13358.6 OAG14371.1 - 3.3e-12 46.4 2.3 3.4e-12 46.3 2.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 OAG14372.1 - 2.9e-11 43.0 1.1 8.1e-10 38.3 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OAG14372.1 - 1.7e-08 34.6 11.8 3e-08 33.8 3.1 3.1 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.6 OAG14372.1 - 3.6e-06 26.9 0.7 2.6e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 OAG14372.1 - 5.3e-05 22.9 5.0 0.00058 19.6 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 OAG14372.1 - 0.00012 21.9 0.1 0.00074 19.4 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_7 PF02796.15 OAG14372.1 - 0.00014 21.9 3.1 0.88 9.7 1.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 OAG14372.1 - 0.00027 20.4 0.4 0.0012 18.4 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 OAG14372.1 - 0.00031 20.8 0.3 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4817 PF16087.5 OAG14372.1 - 0.0024 17.7 2.2 0.46 10.3 0.4 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain (DUF4817) HTH_32 PF13565.6 OAG14372.1 - 0.0051 17.4 3.5 0.25 12.0 0.7 3.2 2 1 0 2 2 2 1 Homeodomain-like domain LacI PF00356.21 OAG14372.1 - 0.006 16.4 1.5 0.023 14.5 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_36 PF13730.6 OAG14372.1 - 0.0091 15.9 0.8 0.048 13.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 OAG14372.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase Sigma70_r4 PF04545.16 OAG14372.1 - 0.015 14.8 0.6 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 OAG14372.1 - 0.018 15.1 0.2 0.11 12.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix HTH_31 PF13560.6 OAG14372.1 - 0.019 15.3 0.1 0.019 15.3 0.1 2.4 2 2 1 3 3 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 OAG14372.1 - 0.022 14.9 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_IclR PF09339.10 OAG14372.1 - 0.029 14.2 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_40 PF14493.6 OAG14372.1 - 0.056 13.9 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 OAG14372.1 - 0.077 13.2 3.1 0.83 9.9 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 OAG14372.1 - 0.09 12.9 0.3 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Phage_AlpA PF05930.12 OAG14372.1 - 0.11 12.4 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Aminotran_1_2 PF00155.21 OAG14374.1 - 8.8e-47 160.0 0.0 1.1e-46 159.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4083 PF13314.6 OAG14375.1 - 4.3 7.4 9.1 0.58 10.1 1.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Peptidase_S9 PF00326.21 OAG14377.1 - 3e-46 157.6 1.2 3e-46 157.6 1.2 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 OAG14377.1 - 3.2e-31 108.4 2.4 4.9e-31 107.8 2.4 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 OAG14377.1 - 7.4e-07 29.0 0.2 9.3e-05 22.1 0.2 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAG14377.1 - 0.0002 21.1 0.3 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 OAG14377.1 - 0.00054 19.6 0.0 0.0023 17.5 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAG14377.1 - 0.027 14.4 0.0 3.7 7.4 0.0 2.7 1 1 2 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAG14377.1 - 0.053 12.8 0.2 0.37 10.0 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 RGI_lyase PF18370.1 OAG14378.1 - 1.2e-19 70.4 0.0 2.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 OAG14378.1 - 0.0068 17.0 11.6 0.52 10.9 0.1 5.0 4 1 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 OAG14378.1 - 0.019 14.9 0.3 0.19 11.7 0.1 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Pyr_redox_2 PF07992.14 OAG14379.1 - 1.6e-17 63.7 0.0 7.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG14379.1 - 4.9e-12 45.1 0.1 1.5e-11 43.5 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG14379.1 - 3e-11 43.0 0.0 5.4e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG14379.1 - 1.6e-10 41.0 0.0 9e-10 38.6 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG14379.1 - 3.5e-06 26.5 0.0 2.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG14379.1 - 6.9e-06 26.1 3.8 0.0014 18.7 0.6 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG14379.1 - 0.00049 19.6 0.0 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG14379.1 - 0.0056 16.3 0.1 0.13 11.8 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG14379.1 - 0.022 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG14379.1 - 0.028 13.6 0.3 0.36 10.0 0.1 2.5 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 OAG14379.1 - 0.058 14.0 0.1 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG14379.1 - 0.23 10.1 0.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans_2 PF11951.8 OAG14380.1 - 5.6e-32 111.0 2.0 7.3e-32 110.6 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14380.1 - 7.2e-08 32.4 9.7 1.8e-07 31.2 9.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 OAG14380.1 - 0.69 10.4 7.1 1.5 9.3 7.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Amino_oxidase PF01593.24 OAG14381.1 - 3.2e-53 181.6 0.0 4.2e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 OAG14381.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 OAG14381.1 - 6.7e-13 48.7 0.3 2.5e-12 46.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG14381.1 - 2.3e-08 33.8 0.1 3.4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG14381.1 - 1.2e-07 31.6 1.7 1.2e-06 28.4 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG14381.1 - 2.2e-07 30.3 0.8 5.8e-07 28.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG14381.1 - 2.8e-07 29.6 0.3 8.4e-06 24.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG14381.1 - 4.2e-07 29.4 0.8 4.2e-05 22.8 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG14381.1 - 4.1e-06 26.3 0.2 0.068 12.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG14381.1 - 1.4e-05 24.4 0.1 0.00045 19.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG14381.1 - 4.7e-05 22.7 0.0 8.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAG14381.1 - 6.9e-05 23.3 0.1 0.00019 21.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG14381.1 - 0.0026 17.0 0.4 0.0038 16.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG14381.1 - 0.005 15.9 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG14381.1 - 0.0094 16.0 0.4 5.3 7.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAG14381.1 - 0.06 12.2 0.2 0.089 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_M16 PF00675.20 OAG14382.1 - 4.5e-13 49.4 0.0 9.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG14382.1 - 3.7e-10 40.1 0.1 1.1e-09 38.6 0.0 1.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 OAG14383.1 - 1e-52 179.5 0.0 4.2e-48 164.4 0.0 2.9 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 OAG14383.1 - 5.1e-20 71.3 2.0 3.1e-14 52.8 0.1 4.1 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 OAG14383.1 - 0.0022 17.8 0.8 2.8 7.8 0.7 2.9 2 1 1 3 3 3 2 TFIIE alpha subunit DAOA PF15199.6 OAG14384.1 - 0.1 13.1 0.4 0.27 11.7 0.4 1.8 1 1 0 1 1 1 0 D-amino acid oxidase activator HET PF06985.11 OAG14385.1 - 2.7e-26 92.7 0.0 4.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyoxalase PF00903.25 OAG14386.1 - 0.093 12.9 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Mid1 PF12929.7 OAG14387.1 - 3.1e-151 504.4 2.8 3.6e-151 504.2 2.8 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAG14387.1 - 0.00088 19.9 8.9 0.0043 17.7 1.3 2.8 3 0 0 3 3 3 2 Fz domain Glyco_hydro_6 PF01341.17 OAG14388.1 - 3.4e-108 362.0 0.3 4.5e-108 361.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SnoaL_4 PF13577.6 OAG14389.1 - 3e-08 33.8 0.2 4.9e-08 33.2 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG14389.1 - 0.00074 20.1 0.1 0.00093 19.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG14389.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HET PF06985.11 OAG14390.1 - 2.2e-34 118.9 0.0 4.2e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CnrY PF17524.2 OAG14390.1 - 0.091 13.0 0.1 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma factor CnrY Fungal_trans_2 PF11951.8 OAG14391.1 - 3.1e-23 82.2 0.3 6.7e-12 44.9 0.2 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14391.1 - 0.00014 21.9 8.5 0.00014 21.9 8.5 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIDE PF12483.8 OAG14391.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase Amino_oxidase PF01593.24 OAG14392.1 - 7.6e-52 177.1 0.1 8.8e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG14392.1 - 1.2e-12 47.8 0.2 2.7e-12 46.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG14392.1 - 7.2e-09 35.5 0.0 8.3e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG14392.1 - 1.4e-07 31.0 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG14392.1 - 1.7e-07 31.1 3.8 2.7e-06 27.2 3.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG14392.1 - 4.5e-07 29.4 0.0 0.00012 21.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG14392.1 - 2e-06 27.2 0.3 3.9e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG14392.1 - 9e-06 24.6 0.0 0.0002 20.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG14392.1 - 3.8e-05 23.1 0.1 0.17 11.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG14392.1 - 4e-05 22.9 0.0 7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG14392.1 - 0.00097 18.3 0.0 0.0053 15.9 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG14392.1 - 0.001 19.6 0.1 0.012 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG14392.1 - 0.04 13.2 0.1 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAG14392.1 - 0.089 12.8 0.3 19 5.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pab87_oct PF13969.6 OAG14393.1 - 0.055 13.5 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Pab87 octamerisation domain Mak10 PF04112.13 OAG14395.1 - 3.2e-59 199.2 0.0 4.7e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Proteasome PF00227.26 OAG14396.1 - 1.3e-49 168.3 0.1 2.2e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit ATP-synt_Eps PF04627.13 OAG14396.1 - 4.9e-22 77.7 2.2 4.9e-22 77.7 2.2 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Proteasome_A_N PF10584.9 OAG14396.1 - 3.7e-12 45.7 0.3 7.6e-12 44.7 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 OAG14396.1 - 0.099 12.5 1.5 3.4 7.6 0.1 2.9 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.14 OAG14397.1 - 5.7e-42 142.4 6.3 6.4e-42 142.2 6.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 OAG14397.1 - 0.099 12.1 0.1 0.099 12.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Nramp PF01566.18 OAG14397.1 - 1.7 7.5 10.6 0.87 8.5 3.3 2.0 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein UPF0220 PF05255.11 OAG14398.1 - 1.2e-69 233.1 3.4 1.4e-69 232.9 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Abhydrolase_1 PF00561.20 OAG14400.1 - 1.8e-09 37.6 0.1 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14400.1 - 0.00016 21.1 0.0 0.00097 18.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cohesin_load PF10345.9 OAG14401.1 - 8.8e-115 384.4 0.0 1e-114 384.2 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Zn_clus PF00172.18 OAG14402.1 - 1.7e-07 31.2 5.8 1.7e-07 31.2 5.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG14402.1 - 0.0023 17.0 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 OAG14403.1 - 1.3e-62 211.4 0.0 2.6e-62 210.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG14403.1 - 3.7e-43 148.1 0.0 5.7e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG14403.1 - 6.7e-21 74.2 0.0 1.2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG14403.1 - 6.6e-13 48.7 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF4058 PF13267.6 OAG14403.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Sugar_tr PF00083.24 OAG14404.1 - 5.9e-74 249.6 21.7 7.3e-74 249.3 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG14404.1 - 5.6e-15 55.1 31.5 5.6e-15 55.1 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAG14405.1 - 4e-08 33.3 0.5 8.6e-08 32.2 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 OAG14405.1 - 0.021 15.2 0.2 0.04 14.4 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG14405.1 - 0.023 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG14405.1 - 0.048 13.0 1.6 0.082 12.2 1.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 OAG14405.1 - 0.11 12.6 0.5 0.2 11.8 0.5 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Helo_like_N PF17111.5 OAG14406.1 - 4.1e-06 26.3 0.1 1e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Abhydrolase_6 PF12697.7 OAG14407.1 - 1.8e-08 35.3 0.1 2.4e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_GDSL_2 PF13472.6 OAG14409.1 - 2.9e-21 76.7 0.0 3.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG14409.1 - 1.2e-13 51.5 0.0 1.9e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 OAG14409.1 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 OAG14409.1 - 2.1e-05 24.8 0.0 2.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ECH_1 PF00378.20 OAG14410.1 - 9.5e-29 100.4 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG14410.1 - 2.5e-09 37.1 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_43 PF04616.14 OAG14411.1 - 3.8e-69 233.2 3.4 4.9e-69 232.8 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG14411.1 - 3.6e-37 128.1 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1996 PF09362.10 OAG14412.1 - 2.4e-81 273.1 1.2 4.7e-81 272.2 1.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) AidB_N PF18158.1 OAG14413.1 - 1.5e-12 47.7 0.0 3.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG14413.1 - 3.3e-12 46.9 0.5 2.8e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG14413.1 - 7e-11 42.2 0.0 4.5e-10 39.6 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.16 OAG14414.1 - 1.8e-33 116.0 27.5 1.8e-33 116.0 27.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14414.1 - 7.5e-11 41.5 5.8 7.5e-11 41.5 5.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.25 OAG14415.1 - 6.9e-51 172.5 1.1 8.5e-51 172.2 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14415.1 - 7.2e-47 159.9 0.9 3.6e-46 157.6 0.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG14415.1 - 3.6e-06 27.0 0.9 1.3e-05 25.2 0.9 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG14415.1 - 5.2e-06 26.1 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG14415.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 OAG14415.1 - 0.0049 16.8 0.2 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 OAG14415.1 - 0.022 14.5 0.1 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_25 PF01755.17 OAG14416.1 - 6e-08 32.8 0.0 4.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_3 PF13641.6 OAG14417.1 - 1.2e-20 74.4 0.0 2.9e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG14417.1 - 4.8e-17 62.3 0.0 7.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAG14417.1 - 1.1e-13 51.6 1.3 1.1e-13 51.6 1.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAG14417.1 - 4.7e-11 42.5 0.0 7.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 OAG14417.1 - 5.1e-08 31.9 0.1 0.0081 14.7 0.2 3.1 1 1 2 3 3 3 3 Cellulose synthase HET PF06985.11 OAG14418.1 - 1.4e-34 119.5 1.1 2.7e-34 118.6 1.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 OAG14419.1 - 1.2e-06 28.2 1.9 1.2e-06 28.2 1.9 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG14419.1 - 3e-05 23.8 0.4 6.5e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like SAE2 PF08573.10 OAG14420.1 - 2.3e-32 112.4 0.4 2.3e-32 112.4 0.4 4.9 4 2 1 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Nif11 PF07862.11 OAG14420.1 - 0.06 13.7 1.1 4.6 7.6 0.2 2.9 2 0 0 2 2 2 0 Nif11 domain bZIP_2 PF07716.15 OAG14420.1 - 1.7 8.8 22.2 0.65 10.1 0.7 5.4 4 0 0 4 4 4 0 Basic region leucine zipper Z1 PF10593.9 OAG14420.1 - 3.6 7.0 10.4 0.44 10.0 0.0 3.3 2 1 0 3 3 3 0 Z1 domain YabA PF06156.13 OAG14420.1 - 5.9 7.6 27.3 0.044 14.4 2.7 4.0 2 1 1 3 3 3 0 Initiation control protein YabA Glyco_hydro_61 PF03443.14 OAG14421.1 - 1.6e-52 178.5 0.1 2e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BmKX PF09132.10 OAG14421.1 - 0.14 12.1 2.0 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 BmKX Glyco_hydro_85 PF03644.13 OAG14422.1 - 2.4e-77 260.4 0.0 3.3e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 ER_lumen_recept PF00810.18 OAG14423.1 - 1.1e-55 188.5 9.5 1.8e-55 187.8 9.5 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAG14423.1 - 0.065 13.0 11.0 2 8.3 0.2 4.3 5 0 0 5 5 5 0 PQ loop repeat BC10 PF06726.12 OAG14424.1 - 2.1e-12 47.1 9.5 3e-12 46.6 9.5 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 ERAP1_C PF11838.8 OAG14425.1 - 1.4e-84 284.4 0.1 3.1e-84 283.2 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAG14425.1 - 2.6e-84 282.2 4.3 3.5e-84 281.7 3.4 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAG14425.1 - 2.4e-44 151.7 0.5 7.2e-43 146.9 0.1 2.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 OAG14425.1 - 0.081 13.0 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF45 CAP_GLY PF01302.25 OAG14426.1 - 1.2e-25 89.3 0.1 1.6e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAG14426.1 - 2.8e-20 72.5 0.0 4.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OAG14426.1 - 0.00027 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 OAG14428.1 - 1.5e-14 53.9 2.7 4.5e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG14428.1 - 7.5e-07 29.3 2.9 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 OAG14428.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Mif2_N PF15624.6 OAG14431.1 - 1.1e-38 133.0 4.0 1.1e-38 133.0 4.0 3.9 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 OAG14431.1 - 7.4e-15 54.9 0.2 1.4e-14 54.1 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like zf-CCHC PF00098.23 OAG14432.1 - 1.3e-14 53.5 18.9 3.5e-08 33.1 2.6 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 OAG14432.1 - 0.00013 21.7 8.8 0.045 13.5 1.8 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 OAG14432.1 - 0.0015 18.3 10.5 0.049 13.5 2.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 OAG14432.1 - 0.0034 17.3 13.7 0.12 12.4 1.4 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 OAG14432.1 - 0.03 14.0 5.1 0.19 11.5 0.5 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-ribbon_3 PF13248.6 OAG14432.1 - 1.2 8.6 7.4 1.2 8.6 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Polysacc_deac_1 PF01522.21 OAG14433.1 - 8.1e-27 93.6 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG14433.1 - 3.2e-08 33.9 18.1 3.2e-08 33.9 18.1 1.9 2 0 0 2 2 2 1 Chitin recognition protein HET PF06985.11 OAG14434.1 - 8e-34 117.1 0.5 1.3e-33 116.4 0.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tecti-min-caps PF09300.10 OAG14435.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Tectiviridae, minor capsid DUF445 PF04286.12 OAG14436.1 - 0.001 18.9 4.8 0.001 18.9 4.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF445) Ge1_WD40 PF16529.5 OAG14436.1 - 0.057 12.4 0.1 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1664 PF07889.12 OAG14436.1 - 3.1 7.8 4.6 43 4.2 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MARVEL PF01284.23 OAG14437.1 - 3e-17 63.0 14.0 3.9e-17 62.6 14.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DPM3 PF08285.11 OAG14437.1 - 1.1 9.6 5.8 5.2 7.3 1.9 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 OAG14437.1 - 1.8 8.7 9.4 1 9.4 4.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF485 PF04341.12 OAG14437.1 - 9.7 6.2 12.5 16 5.5 3.5 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Peptidase_M20 PF01546.28 OAG14439.1 - 9.1e-32 110.4 0.1 1.3e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG14439.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG14439.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Amidohydro_1 PF01979.20 OAG14440.1 - 6.2e-13 48.8 0.0 1.1e-12 47.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG14440.1 - 0.00067 19.2 0.0 0.012 15.1 0.0 2.5 2 1 1 3 3 3 1 Amidohydrolase family FAD_binding_3 PF01494.19 OAG14441.1 - 1.9e-62 211.6 0.0 2.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG14441.1 - 2.8e-06 27.5 0.0 1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG14441.1 - 3.1e-06 27.0 0.1 6.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG14441.1 - 0.00013 20.9 0.0 0.00025 20.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 OAG14441.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAG14441.1 - 0.0022 18.0 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG14441.1 - 0.0031 17.7 0.1 0.0098 16.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG14441.1 - 0.075 12.2 0.1 0.3 10.3 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG14441.1 - 0.14 10.8 0.0 0.33 9.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein CorA PF01544.18 OAG14442.1 - 3.6e-14 52.8 0.4 9.2e-14 51.4 0.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4199 PF13858.6 OAG14442.1 - 0.00073 20.0 0.6 0.0016 18.8 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4199) EMP70 PF02990.16 OAG14442.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF5345 PF17280.2 OAG14442.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5345) PRONE PF03759.13 OAG14443.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Beta-lactamase PF00144.24 OAG14444.1 - 1.6e-38 132.8 0.0 3.4e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase HET PF06985.11 OAG14445.1 - 4.7e-28 98.4 3.2 6.1e-27 94.8 3.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3818 PF12825.7 OAG14447.1 - 1.4e-59 201.8 0.0 4.3e-57 193.6 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG14447.1 - 8e-38 129.4 0.0 1.9e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 PX-associated DUF2162 PF09930.9 OAG14452.1 - 0.17 11.3 3.8 4.1 6.8 4.7 2.0 1 1 0 1 1 1 0 Predicted transporter (DUF2162) NMN_transporter PF04973.12 OAG14452.1 - 0.2 11.6 9.0 0.23 11.4 0.4 2.2 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Phage_holin_5_2 PF16079.5 OAG14452.1 - 0.59 10.5 4.1 17 5.8 0.1 2.7 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Form_Nir_trans PF01226.17 OAG14452.1 - 0.61 9.4 8.2 0.053 12.8 0.8 2.0 2 0 0 2 2 2 0 Formate/nitrite transporter HTH_32 PF13565.6 OAG14453.1 - 0.053 14.2 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Aft1_OSA PF11785.8 OAG14454.1 - 0.013 15.9 0.3 0.17 12.3 0.2 2.3 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain Acyl-CoA_dh_1 PF00441.24 OAG14455.1 - 1.6e-37 129.1 0.2 2.1e-37 128.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG14455.1 - 9e-19 67.5 0.1 1.7e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG14455.1 - 1.7e-12 47.8 0.0 2.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG14455.1 - 1.6e-09 38.4 0.0 1.1e-08 35.7 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 OAG14455.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PH_BEACH PF14844.6 OAG14455.1 - 0.13 12.3 0.0 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH DEAD_2 PF06733.15 OAG14455.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 Pec_lyase_C PF00544.19 OAG14458.1 - 6.5e-17 61.8 5.2 4e-16 59.2 5.2 2.0 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 OAG14458.1 - 2.3e-13 49.9 7.3 2.3e-13 49.9 7.3 3.0 2 1 1 3 3 3 1 Fungal cellulose binding domain Beta_helix PF13229.6 OAG14458.1 - 4.7e-05 23.3 3.8 8.4e-05 22.5 3.8 1.4 1 0 0 1 1 1 1 Right handed beta helix region HET PF06985.11 OAG14461.1 - 2.3e-16 60.5 0.7 1.2e-15 58.2 0.7 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YgaB PF14182.6 OAG14462.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 YgaB-like protein Ank_2 PF12796.7 OAG14463.1 - 3.9e-20 72.2 1.2 9.7e-10 38.9 0.4 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG14463.1 - 9.4e-16 56.3 2.4 0.00031 20.9 0.1 6.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 OAG14463.1 - 3.6e-13 49.5 2.0 0.00031 21.0 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG14463.1 - 5.8e-13 49.1 2.1 1e-05 26.0 0.0 5.1 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG14463.1 - 4e-08 33.4 6.3 0.21 12.1 0.3 5.7 6 0 0 6 6 6 3 Ankyrin repeat HATPase_c PF02518.26 OAG14464.1 - 2.1e-19 70.1 0.0 4.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG14464.1 - 3.2e-17 62.7 0.3 6.8e-16 58.4 0.3 2.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG14464.1 - 3.2e-15 55.9 0.0 8.1e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain YDG PF18657.1 OAG14465.1 - 0.095 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 YDG domain Zn_clus PF00172.18 OAG14465.1 - 0.34 11.1 4.3 0.69 10.1 4.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYND PF01753.18 OAG14468.1 - 2.5e-07 30.7 12.8 5.8e-07 29.5 12.8 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OAG14468.1 - 1.6 8.9 7.7 3.5 7.8 7.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 OAG14469.1 - 3e-09 36.8 12.9 6.1e-09 35.8 12.9 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG14469.1 - 0.017 15.4 9.9 0.045 14.1 9.9 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 OAG14469.1 - 0.17 11.8 6.1 0.33 10.8 6.1 1.5 1 0 0 1 1 1 0 HIT zinc finger Glyco_hydro_10 PF00331.20 OAG14470.1 - 8.7e-102 340.5 0.1 1e-101 340.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 OAG14470.1 - 0.0001 21.8 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Glyco_hydro_1 PF00232.18 OAG14470.1 - 0.0038 15.7 0.2 0.011 14.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 1 Asp PF00026.23 OAG14472.1 - 3.6e-06 26.6 0.2 0.085 12.3 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease DUF2613 PF11021.8 OAG14472.1 - 0.011 15.9 0.3 0.045 13.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) TAXi_N PF14543.6 OAG14472.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Trp_oprn_chp PF09534.10 OAG14472.1 - 0.016 15.0 0.2 0.039 13.8 0.2 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4328 PF14219.6 OAG14472.1 - 0.064 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Methyltransf_2 PF00891.18 OAG14473.1 - 7.4e-18 64.6 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain KAP_NTPase PF07693.14 OAG14473.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Dimerisation PF08100.11 OAG14473.1 - 0.38 10.8 4.4 3.2 7.8 3.5 2.7 2 1 0 2 2 2 0 Dimerisation domain GMC_oxred_N PF00732.19 OAG14475.1 - 2.5e-60 204.4 0.0 3.6e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG14475.1 - 1.3e-33 116.5 0.0 2.8e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG14475.1 - 5.4e-05 22.5 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG14475.1 - 0.00015 22.0 0.1 0.00048 20.3 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG14475.1 - 0.00089 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG14475.1 - 0.0035 17.0 0.7 0.022 14.3 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG14475.1 - 0.0076 15.5 0.1 0.67 9.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG14475.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Mon2_C PF16206.5 OAG14475.1 - 0.17 10.0 0.0 0.66 8.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of Mon2 protein TPR_9 PF13371.6 OAG14477.1 - 0.036 14.2 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG14477.1 - 0.1 13.5 1.6 0.24 12.3 1.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Dimerisation2 PF16864.5 OAG14478.1 - 0.045 13.7 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 OAG14478.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain adh_short PF00106.25 OAG14479.1 - 1.5e-36 125.7 0.1 2.2e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14479.1 - 2e-26 93.0 0.0 2.9e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG14479.1 - 3.3e-09 36.9 0.3 1.1e-08 35.2 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG14479.1 - 2.9e-05 23.7 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG14479.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 OAG14479.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 OAG14480.1 - 4.1e-20 72.1 0.3 2.5e-17 63.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14480.1 - 1.3e-10 41.3 0.0 4.9e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG14480.1 - 1.2e-05 25.3 0.2 1.8e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Av_adeno_fibre PF06536.11 OAG14480.1 - 0.1 12.5 1.3 9.2 6.2 0.1 2.4 2 0 0 2 2 2 0 Avian adenovirus fibre, N-terminal p450 PF00067.22 OAG14481.1 - 5.3e-73 246.3 0.0 6.4e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTP PF05232.12 OAG14481.1 - 0.05 13.7 1.0 0.11 12.5 1.0 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter p450 PF00067.22 OAG14482.1 - 3.9e-47 161.1 0.0 5.2e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1280 PF06918.14 OAG14482.1 - 0.15 11.6 0.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) KR PF08659.10 OAG14483.1 - 4.3e-63 212.5 0.1 1.1e-62 211.2 0.1 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 OAG14483.1 - 1.1e-62 211.9 0.2 3.6e-61 206.9 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAG14483.1 - 2.3e-40 138.7 0.0 3.8e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG14483.1 - 2.3e-39 134.0 0.0 5.7e-39 132.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 OAG14483.1 - 5.4e-38 131.3 0.0 8.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ADH_zinc_N PF00107.26 OAG14483.1 - 2.4e-17 63.1 0.2 8.3e-17 61.4 0.1 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 OAG14483.1 - 2.6e-14 53.8 0.0 8.4e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG14483.1 - 8.1e-13 48.8 0.0 1.5e-11 44.7 0.0 2.8 2 1 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG14483.1 - 7.2e-11 41.9 0.2 2.5e-10 40.1 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 OAG14483.1 - 4e-10 40.8 0.0 5e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 OAG14483.1 - 8.7e-09 35.9 0.0 3.6e-08 33.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG14483.1 - 2.8e-07 31.2 0.0 1.6e-06 28.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG14483.1 - 4e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG14483.1 - 2.7e-05 24.0 0.0 9.2e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 OAG14483.1 - 5.2e-05 22.7 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 OAG14483.1 - 8.8e-05 22.8 0.0 0.00024 21.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 OAG14483.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 OAG14483.1 - 0.011 15.5 1.0 0.14 11.8 0.1 2.8 2 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 OAG14483.1 - 0.025 14.4 0.2 0.084 12.7 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 OAG14483.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_31 PF01055.26 OAG14485.1 - 1.4e-131 439.8 4.1 1.8e-131 439.3 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG14485.1 - 9.8e-22 77.3 0.0 2.4e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 OAG14485.1 - 0.049 13.0 0.6 0.16 11.3 0.0 2.1 2 1 1 3 3 3 0 Rotavirus major outer capsid protein VP7 GHL15 PF14885.6 OAG14485.1 - 0.049 13.6 2.9 0.033 14.1 1.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Apt1 PF10351.9 OAG14486.1 - 1.9 7.2 9.1 1.8 7.3 9.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 OAG14486.1 - 3 7.5 7.9 3.9 7.1 7.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 OAG14486.1 - 3.9 5.9 12.3 3.7 6.0 12.3 1.2 1 0 0 1 1 1 0 Macoilin family TraG-D_C PF12696.7 OAG14486.1 - 7.1 6.6 8.3 14 5.7 8.3 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG PI3K_1B_p101 PF10486.9 OAG14486.1 - 8 4.1 17.1 8.7 4.0 17.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ring_hydroxyl_A PF00848.19 OAG14487.1 - 2.1e-21 76.9 4.2 9.3e-19 68.2 4.2 2.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG14487.1 - 1.1e-16 60.5 0.0 2.6e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MARVEL PF01284.23 OAG14488.1 - 1.8e-05 24.8 8.3 2.1e-05 24.6 7.9 1.3 1 1 0 1 1 1 1 Membrane-associating domain SET PF00856.28 OAG14489.1 - 1.1e-13 51.9 0.0 8.3e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 OAG14489.1 - 6.7e-10 39.8 4.0 1.7e-09 38.4 4.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding PhoU PF01895.19 OAG14489.1 - 0.053 14.0 0.6 0.16 12.5 0.2 1.9 1 1 0 1 1 1 0 PhoU domain BIRC6 PF12356.8 OAG14490.1 - 0.089 12.2 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Borrelia_lipo_1 PF05714.11 OAG14490.1 - 0.16 11.8 0.6 0.26 11.0 0.6 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein zf-RING_2 PF13639.6 OAG14491.1 - 0.00032 20.9 0.2 0.00032 20.9 0.2 3.8 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG14491.1 - 0.00047 20.1 0.4 0.00047 20.1 0.4 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG14491.1 - 0.0005 20.0 0.1 0.0005 20.0 0.1 2.8 3 0 0 3 3 3 2 zinc-RING finger domain Piezo_RRas_bdg PF12166.8 OAG14491.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Inhibitor_I29 PF08246.12 OAG14491.1 - 0.053 14.0 0.1 0.088 13.3 0.1 1.3 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) MFS_1 PF07690.16 OAG14492.1 - 6.2e-18 64.8 54.7 4.1e-15 55.6 54.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PetG PF02529.15 OAG14492.1 - 3.6 7.5 9.6 7.3 6.5 0.2 3.4 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit 5 AATase PF07247.12 OAG14493.1 - 3e-10 39.3 0.0 1.7e-08 33.5 0.0 2.8 2 1 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.20 OAG14493.1 - 0.025 13.3 0.2 0.064 11.9 0.1 1.6 2 0 0 2 2 2 0 Condensation domain Abhydrolase_3 PF07859.13 OAG14494.1 - 1.4e-45 155.7 0.1 1.8e-45 155.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG14494.1 - 5.1e-11 42.1 0.0 1.1e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DIT1_PvcA PF05141.12 OAG14497.1 - 1.6e-94 316.5 0.0 8.5e-94 314.1 0.0 2.0 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 OAG14497.1 - 4.9e-27 94.6 0.0 9.5e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG14497.1 - 1.5e-08 34.9 0.1 3.4e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 OAG14497.1 - 3.2e-07 29.4 0.0 0.0049 15.6 0.0 2.5 2 1 0 2 2 2 2 Transferase family Hamartin PF04388.12 OAG14497.1 - 0.023 13.4 0.6 0.039 12.6 0.6 1.2 1 0 0 1 1 1 0 Hamartin protein WW_1 PF18507.1 OAG14497.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF1769 PF08588.10 OAG14498.1 - 1.5e-24 86.0 0.4 2.8e-24 85.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.20 OAG14499.1 - 4.2e-95 318.8 0.0 6.1e-95 318.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3506 PF12014.8 OAG14500.1 - 8.8e-54 181.3 0.0 2.1e-53 180.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 OAG14500.1 - 5.6e-09 35.6 0.2 1.2e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG14500.1 - 5.5e-08 32.6 0.3 1.2e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 OAG14500.1 - 0.016 15.7 0.2 0.035 14.6 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pkinase PF00069.25 OAG14501.1 - 8.2e-44 149.9 0.0 4.7e-30 104.8 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14501.1 - 1.5e-21 76.8 0.2 3.4e-15 56.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 OAG14501.1 - 0.0001 21.8 0.2 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG14501.1 - 0.066 12.0 5.5 0.42 9.3 0.0 2.9 3 0 0 3 3 3 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OAG14501.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HET PF06985.11 OAG14502.1 - 3.2e-23 82.7 0.0 7.4e-23 81.5 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Polysacc_deac_1 PF01522.21 OAG14503.1 - 3.6e-27 94.7 0.0 5.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG14503.1 - 0.00048 20.5 17.8 0.0012 19.3 17.8 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 OAG14503.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) FAM199X PF15814.5 OAG14503.1 - 1.8 7.6 6.9 3.1 6.8 6.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X Amino_oxidase PF01593.24 OAG14506.1 - 7.3e-61 206.8 0.0 8.4e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG14506.1 - 1.6e-10 41.1 0.1 3.6e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG14506.1 - 2.8e-06 26.8 1.1 0.015 14.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG14506.1 - 3.7e-05 23.5 0.7 0.00017 21.3 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG14506.1 - 5e-05 23.8 0.3 0.00026 21.5 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG14506.1 - 6e-05 22.3 0.6 9.6e-05 21.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG14506.1 - 0.00021 20.1 0.7 0.0026 16.5 0.4 2.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG14506.1 - 0.00045 19.5 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG14506.1 - 0.00055 19.3 0.2 0.001 18.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAG14506.1 - 0.0042 17.1 2.4 0.036 14.1 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG14506.1 - 0.0073 15.7 1.0 0.011 15.2 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG14506.1 - 0.0099 15.2 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG14506.1 - 0.014 14.7 0.3 0.028 13.7 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SPOUT_MTase PF02590.17 OAG14506.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Lycopene_cycl PF05834.12 OAG14506.1 - 0.077 12.0 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein RTA1 PF04479.13 OAG14507.1 - 7.5e-43 146.5 14.3 7.5e-43 146.5 14.3 1.6 1 1 1 2 2 2 1 RTA1 like protein Fungal_trans PF04082.18 OAG14508.1 - 9.7e-14 51.0 0.1 3.6e-13 49.1 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14508.1 - 8.6e-08 32.2 11.4 1.8e-07 31.1 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3676 PF12429.8 OAG14508.1 - 0.17 11.7 3.4 0.24 11.2 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3676) Ysc84 PF04366.12 OAG14509.1 - 7.7e-41 138.8 0.0 1.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator ArabFuran-catal PF09206.11 OAG14510.1 - 4.3e-153 509.2 13.6 4.3e-153 509.2 13.6 1.6 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 OAG14510.1 - 1.3e-54 184.0 2.9 2e-54 183.4 2.9 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Aldo_ket_red PF00248.21 OAG14514.1 - 1.6e-45 155.5 0.0 1.8e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavodoxin_2 PF02525.17 OAG14514.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold FAD_binding_3 PF01494.19 OAG14515.1 - 4.2e-24 85.4 0.2 6.4e-24 84.9 0.2 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG14515.1 - 1e-09 38.5 0.7 1.2e-05 25.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG14515.1 - 3.6e-08 33.0 0.2 6.4e-08 32.2 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG14515.1 - 3.7e-07 30.3 0.3 9.4e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG14515.1 - 7e-05 22.1 0.2 0.00014 21.1 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 OAG14515.1 - 0.0003 19.9 0.0 0.015 14.3 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.24 OAG14515.1 - 0.0053 16.1 0.6 1.3 8.2 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG14515.1 - 0.0056 16.0 0.3 0.013 14.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAG14515.1 - 0.0069 16.9 0.2 0.015 15.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG14515.1 - 0.021 13.5 0.2 0.08 11.6 0.2 1.9 1 1 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 OAG14515.1 - 0.052 12.6 0.6 2.3 7.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG14515.1 - 0.079 11.8 1.2 0.49 9.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG14515.1 - 0.12 12.4 1.8 6 6.8 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG14515.1 - 0.14 11.3 0.3 1.1 8.4 0.2 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Syja_N PF02383.18 OAG14516.1 - 3.6e-78 263.1 0.0 4.3e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 OAG14517.1 - 2.5e-59 199.5 0.4 2.9e-59 199.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG14517.1 - 3.6e-36 124.0 0.2 7.1e-36 123.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG14517.1 - 4.1e-15 55.7 0.0 5.1e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG14517.1 - 7.2e-07 28.9 0.1 1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG14517.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG14517.1 - 2.3e-06 27.1 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAG14517.1 - 1.2e-05 25.3 1.6 0.07 13.0 0.3 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG14517.1 - 0.0073 16.7 0.2 0.014 15.8 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OAG14517.1 - 0.097 12.1 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAG14517.1 - 0.11 12.7 0.0 3.6 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OAG14517.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAT PF03417.16 OAG14517.1 - 0.17 11.6 0.2 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase HET PF06985.11 OAG14520.1 - 9.1e-30 103.9 0.3 1.5e-29 103.2 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 OAG14521.1 - 2e-41 142.3 0.0 2.4e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mitofilin PF09731.9 OAG14522.1 - 2.6e-137 459.3 27.1 1.9e-116 390.4 31.4 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Mer2 PF09074.10 OAG14522.1 - 0.059 13.2 9.6 0.11 12.4 9.6 1.4 1 0 0 1 1 1 0 Mer2 V-ATPase_G_2 PF16999.5 OAG14522.1 - 0.14 12.5 16.4 0.2 12.1 15.0 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ALMT PF11744.8 OAG14522.1 - 0.26 10.1 13.7 0.38 9.5 13.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1515 PF07439.11 OAG14522.1 - 0.72 9.9 3.9 0.53 10.3 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FIVAR PF07554.13 OAG14522.1 - 5.4 7.8 11.3 4.6 8.1 3.7 3.1 1 1 0 2 2 2 0 FIVAR domain Pro-kuma_activ PF09286.11 OAG14524.1 - 1.9e-41 141.7 1.2 3.7e-41 140.7 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG14524.1 - 2.6e-06 26.9 0.0 1.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Subtilase family DUF1233 PF06806.12 OAG14524.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) HET PF06985.11 OAG14525.1 - 7.2e-23 81.6 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 OAG14526.1 - 8.3e-26 90.7 25.8 1.5e-14 54.2 9.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DapB_N PF01113.20 OAG14527.1 - 0.026 14.7 0.0 0.096 12.8 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Hemagglutinin PF00509.18 OAG14527.1 - 0.064 11.7 0.0 0.093 11.1 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin NolV PF06635.12 OAG14528.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein NolV FANCD2OS PF15124.6 OAG14528.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 FANCD2 opposite strand protein DUF3020 PF11223.8 OAG14528.1 - 0.45 11.1 2.0 1 9.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) HET PF06985.11 OAG14530.1 - 9.9e-16 58.4 0.1 2.1e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG14531.1 - 6.1e-11 42.9 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CN_hydrolase PF00795.22 OAG14533.1 - 1.6e-40 139.1 0.0 2.7e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 OAG14533.1 - 2.2e-10 40.8 0.7 7.3e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase WcbI PF18588.1 OAG14533.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Amdase PF17645.1 OAG14533.1 - 0.13 11.9 0.5 0.31 10.6 0.5 1.6 1 1 0 1 1 1 0 Arylmalonate decarboxylase DUF3533 PF12051.8 OAG14534.1 - 9.6e-46 156.4 20.5 1.1e-45 156.2 20.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) 60KD_IMP PF02096.20 OAG14534.1 - 0.044 13.7 2.6 0.061 13.2 1.1 2.0 2 1 0 2 2 2 0 60Kd inner membrane protein p450 PF00067.22 OAG14535.1 - 1.6e-72 244.8 0.0 2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG14536.1 - 9.8e-99 331.2 23.4 1.1e-98 331.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG14536.1 - 4.4e-22 78.5 24.3 4.4e-22 78.5 24.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 OAG14536.1 - 0.11 12.3 1.3 3.5 7.5 0.1 3.6 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PMT_4TMC PF16192.5 OAG14536.1 - 0.92 9.1 6.7 6 6.4 6.7 2.4 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase HET PF06985.11 OAG14537.1 - 2.7e-21 76.4 0.3 3.9e-20 72.7 0.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 OAG14538.1 - 1.6e-55 188.4 0.0 1.8e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family T5orf172 PF10544.9 OAG14540.1 - 1.8e-18 67.0 1.4 3.4e-18 66.1 0.2 2.1 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 OAG14540.1 - 3.2e-09 37.3 0.4 1e-08 35.7 0.4 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 SesA PF17107.5 OAG14541.1 - 0.00061 20.0 4.2 0.001 19.3 0.6 2.7 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases EthD PF07110.11 OAG14542.1 - 0.018 16.2 0.1 0.042 15.0 0.1 1.7 1 0 0 1 1 1 0 EthD domain Acetyltransf_10 PF13673.7 OAG14544.1 - 1.8e-10 40.8 0.0 5.1e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG14544.1 - 4.3e-08 33.4 0.0 8.9e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG14544.1 - 2.7e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fringe PF02434.16 OAG14545.1 - 2.1e-07 30.6 0.6 1.1e-06 28.3 0.6 1.9 1 1 0 1 1 1 1 Fringe-like CBM_4_9 PF02018.17 OAG14546.1 - 7.5e-05 23.0 1.8 0.00012 22.4 1.8 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain BetaGal_dom4_5 PF13364.6 OAG14546.1 - 0.025 15.1 0.4 0.069 13.7 0.4 1.8 1 1 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF3433 PF11915.8 OAG14550.1 - 8.5e-07 29.3 0.3 8.5e-07 29.3 0.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF3433 PF11915.8 OAG14551.1 - 7.9e-19 67.9 5.3 7.9e-19 67.9 5.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF4271 PF14093.6 OAG14551.1 - 3.1 7.7 11.0 0.85 9.5 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) 2-Hacid_dh_C PF02826.19 OAG14552.1 - 5.2e-44 149.7 0.0 2.1e-42 144.5 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG14552.1 - 7.5e-08 32.1 0.0 4.4e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Na_H_Exchanger PF00999.21 OAG14553.1 - 9.4e-46 156.3 23.9 1.2e-45 155.9 23.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Lactonase PF10282.9 OAG14554.1 - 2.8e-24 86.0 5.4 1.5e-22 80.4 4.3 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OAG14554.1 - 0.00086 19.0 1.7 0.016 14.8 0.1 3.1 1 1 2 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Mito_carr PF00153.27 OAG14557.1 - 1.6e-15 56.8 1.8 1.6e-11 44.0 0.0 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein SPT16 PF08644.11 OAG14558.1 - 8.8e-54 181.8 0.2 8.8e-54 181.8 0.2 3.3 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAG14558.1 - 8e-49 165.5 2.9 1.8e-48 164.4 0.5 2.8 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAG14558.1 - 2.2e-27 96.1 0.0 4.5e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAG14558.1 - 2.2e-16 60.0 0.2 1.7e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Sigma_reg_N PF13800.6 OAG14559.1 - 0.5 10.7 1.4 19 5.7 0.1 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Herpes_IE68 PF02479.16 OAG14561.1 - 5.6e-05 22.8 0.2 7.5e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus immediate early protein DUF3039 PF11238.8 OAG14561.1 - 0.06 13.1 1.4 21 5.0 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3039) zf-Sec23_Sec24 PF04810.15 OAG14562.1 - 0.089 12.9 0.5 0.089 12.9 0.5 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Tannase PF07519.11 OAG14565.1 - 2.8e-88 296.9 0.0 3.4e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase T5orf172 PF10544.9 OAG14566.1 - 2.2e-23 82.7 5.5 2.3e-23 82.7 3.7 2.1 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 OAG14566.1 - 8.2e-17 61.7 3.8 8.2e-17 61.7 3.8 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 MazG PF03819.17 OAG14566.1 - 0.12 12.6 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain GIY-YIG PF01541.24 OAG14566.1 - 1.3 9.4 4.3 4.8 7.5 4.3 2.1 1 1 0 1 1 1 0 GIY-YIG catalytic domain HET PF06985.11 OAG14567.1 - 1e-24 87.6 0.0 1.9e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TC1 PF15063.6 OAG14567.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 TM2 PF05154.16 OAG14568.1 - 1.5e-07 31.7 8.9 2.2e-07 31.1 8.7 1.5 1 1 0 1 1 1 1 TM2 domain CoxIIa PF08113.11 OAG14568.1 - 0.018 14.8 0.5 0.054 13.3 0.5 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family HET PF06985.11 OAG14569.1 - 8.9e-21 74.8 0.2 2.6e-20 73.2 0.0 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 OAG14570.1 - 1e-58 198.7 0.0 1.3e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 OAG14571.1 - 3.6e-31 108.5 0.0 3.6e-31 108.5 0.0 1.7 2 0 0 2 2 1 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 OAG14571.1 - 9.8e-05 22.6 0.0 0.041 14.2 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 OAG14571.1 - 0.0091 16.1 7.2 0.016 15.4 7.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 OAG14571.1 - 0.025 14.0 7.5 0.042 13.3 7.5 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAG14571.1 - 0.026 13.9 7.3 0.039 13.3 7.3 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 OAG14571.1 - 0.12 11.4 0.3 0.32 9.9 0.4 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 OAG14571.1 - 0.26 9.5 8.6 0.37 8.9 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 OAG14571.1 - 0.29 11.2 7.6 0.54 10.3 7.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 OAG14571.1 - 0.47 8.7 7.5 0.7 8.1 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 OAG14571.1 - 2.3 8.0 8.4 4 7.2 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sigma70_ner PF04546.13 OAG14571.1 - 7 6.5 8.0 14 5.5 8.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region His_Phos_1 PF00300.22 OAG14572.1 - 5.8e-09 35.9 0.0 1.5e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Toast_rack_N PF17115.5 OAG14574.1 - 0.15 12.4 0.0 14 6.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of toast_rack, DUF2154 5-FTHF_cyc-lig PF01812.20 OAG14575.1 - 7e-09 35.8 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SBF_like PF13593.6 OAG14576.1 - 1.5e-95 320.1 29.1 1.7e-95 319.9 29.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) zf-C2H2 PF00096.26 OAG14579.1 - 1.9e-13 50.1 37.7 0.00068 20.0 0.4 6.6 8 0 0 8 8 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG14579.1 - 4.6e-13 48.8 35.0 0.0014 19.3 2.3 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG14579.1 - 5.8e-06 26.5 29.0 1.2e-05 25.6 1.6 7.3 8 0 0 8 8 8 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAG14579.1 - 0.0012 18.8 13.7 0.04 13.9 1.8 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAG14579.1 - 0.0088 16.3 15.2 0.99 9.7 0.6 3.8 4 1 0 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAG14579.1 - 0.009 16.3 13.3 0.018 15.3 0.1 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAG14579.1 - 0.013 15.8 4.3 0.13 12.6 1.6 3.0 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-BED PF02892.15 OAG14579.1 - 0.041 13.9 8.3 9.7 6.3 0.0 4.5 4 0 0 4 4 4 0 BED zinc finger zf-met PF12874.7 OAG14579.1 - 0.05 14.0 0.0 0.05 14.0 0.0 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BBP1_N PF15271.6 OAG14579.1 - 0.11 13.3 0.1 0.17 12.7 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein zf-C2H2_3rep PF18868.1 OAG14579.1 - 0.16 12.6 5.8 0.57 10.9 4.5 2.5 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 OAG14579.1 - 0.58 10.8 9.6 5.1 7.8 0.9 4.4 4 2 1 5 5 4 0 FOXP coiled-coil domain zinc_ribbon_4 PF13717.6 OAG14579.1 - 2.9 7.9 7.1 1 9.3 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-LSD1 PF06943.12 OAG14579.1 - 7.3 6.5 7.7 16 5.4 0.1 3.9 4 0 0 4 4 4 0 LSD1 zinc finger DUF4225 PF13988.6 OAG14580.1 - 0.24 10.9 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) MF_alpha_N PF05436.11 OAG14581.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.0 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF3632 PF12311.8 OAG14582.1 - 3.5e-17 63.4 12.7 3.5e-17 63.4 12.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) BTB PF00651.31 OAG14583.1 - 3.6e-05 24.0 0.0 6.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NACHT PF05729.12 OAG14584.1 - 0.00016 21.6 0.1 0.0009 19.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG14584.1 - 0.03 14.6 0.0 0.34 11.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 OAG14585.1 - 4.1 7.1 5.0 1.6 8.4 2.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M28 PF04389.17 OAG14586.1 - 4.3e-36 124.5 0.1 2e-35 122.3 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M28 Sugar_tr PF00083.24 OAG14588.1 - 6e-124 414.3 23.2 1.4e-123 413.2 23.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG14588.1 - 1.1e-28 100.3 61.2 5.4e-24 84.8 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.22 OAG14589.1 - 9.6e-18 64.5 2.4 4e-17 62.4 0.0 2.3 2 0 0 2 2 2 1 Subtilase family MGC-24 PF05283.11 OAG14589.1 - 0.48 10.9 11.2 1.1 9.7 11.2 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 OAG14589.1 - 2.7 6.5 4.3 3.6 6.0 4.3 1.1 1 0 0 1 1 1 0 Macoilin family Sod_Fe_C PF02777.18 OAG14591.1 - 2.2e-36 124.1 0.4 3.5e-36 123.5 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAG14591.1 - 1.3e-34 118.5 4.4 2.9e-34 117.4 1.6 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain p450 PF00067.22 OAG14592.1 - 9.8e-57 192.7 0.0 1.2e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 OAG14593.1 - 1.9e-50 171.3 0.0 4.1e-50 170.2 0.0 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 OAG14593.1 - 0.00069 19.0 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain FAD_binding_4 PF01565.23 OAG14594.1 - 1.2e-25 89.9 4.6 2.5e-25 88.8 4.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG14594.1 - 0.00016 21.7 0.2 0.00036 20.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 OAG14595.1 - 2.7e-44 151.7 0.0 3.6e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 OAG14596.1 - 1.1e-15 57.4 35.2 1.8e-15 56.7 35.0 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Asparaginase PF00710.20 OAG14597.1 - 1.5e-32 112.8 0.0 2.5e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG14597.1 - 6.6e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 OAG14597.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 PA domain Glyco_hydro_cc PF11790.8 OAG14598.1 - 3.9e-56 190.3 1.0 4.5e-56 190.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NGP1NT PF08153.12 OAG14600.1 - 1e-44 151.8 0.1 1.7e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAG14600.1 - 2.6e-16 59.7 0.0 2.2e-12 47.1 0.0 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG14600.1 - 5.5e-05 22.7 0.0 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG14600.1 - 0.00055 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 OAG14600.1 - 0.0046 16.4 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 OAG14600.1 - 0.036 14.1 6.4 1.4 9.0 0.0 4.1 3 1 1 4 4 4 0 Dynamin family Cwf_Cwc_15 PF04889.12 OAG14600.1 - 0.64 9.7 18.3 1.6 8.4 18.3 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 OAG14600.1 - 4.3 7.1 15.2 4.5 7.0 13.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 OAG14600.1 - 7.9 4.6 21.9 10 4.1 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family HET PF06985.11 OAG14602.1 - 4.7e-20 72.4 0.0 1.3e-19 71.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_2 PF00891.18 OAG14603.1 - 2e-10 40.3 0.2 7e-10 38.6 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase domain MKLP1_Arf_bdg PF16540.5 OAG14603.1 - 0.048 13.7 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 DUF4423 PF14394.6 OAG14603.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Methyltransf_23 PF13489.6 OAG14604.1 - 3.7e-19 69.1 0.0 6.9e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG14604.1 - 4.5e-13 49.7 0.0 1.4e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG14604.1 - 6.2e-10 39.6 0.0 1.7e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG14604.1 - 1e-09 38.4 0.0 1.3e-07 31.6 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG14604.1 - 1.6e-09 38.4 0.0 1.1e-08 35.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG14604.1 - 0.00014 21.5 0.0 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG14604.1 - 0.00022 20.7 0.0 0.00071 19.1 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 OAG14604.1 - 0.0047 17.1 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAG14604.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 OAG14604.1 - 0.027 13.9 0.1 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAG14604.1 - 0.066 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 OAG14604.1 - 0.14 11.5 0.0 1.3 8.3 0.0 2.3 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Asp PF00026.23 OAG14605.1 - 1.8e-10 40.8 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 OAG14605.1 - 0.0076 15.2 0.3 0.013 14.4 0.3 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein MtrF PF09472.10 OAG14605.1 - 0.41 10.1 2.2 0.53 9.7 0.8 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Cation_ATPase_C PF00689.21 OAG14607.1 - 1.4e-43 148.7 4.6 1.4e-43 148.7 4.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG14607.1 - 2.6e-35 121.6 1.3 2.6e-35 121.6 1.3 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OAG14607.1 - 3.1e-19 70.1 0.3 1.2e-18 68.2 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG14607.1 - 1.8e-18 66.4 0.0 3.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG14607.1 - 1.1e-11 44.2 0.0 7.7e-10 38.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG14607.1 - 2.8e-05 24.0 0.1 0.00073 19.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 OAG14607.1 - 0.19 10.5 4.7 0.4 9.5 3.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Caps_synth PF05704.12 OAG14608.1 - 7.9e-11 41.9 0.9 2.4e-10 40.2 0.9 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG14608.1 - 4.4e-06 27.2 0.0 3.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif tRNA-synt_2 PF00152.20 OAG14609.1 - 1.2e-92 310.4 0.0 1.6e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAG14609.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.25 OAG14609.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG14609.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) MIP PF00230.20 OAG14611.1 - 4.6e-52 177.0 18.1 6e-52 176.6 18.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.6 OAG14612.1 - 3e-12 46.6 4.9 4.7e-12 46.0 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG14612.1 - 5.7e-09 35.7 4.1 9.2e-09 35.0 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG14612.1 - 1.8e-08 34.1 2.6 2.8e-08 33.5 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG14612.1 - 2.5e-08 34.1 3.1 5e-08 33.1 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG14612.1 - 4.8e-08 32.6 2.4 4.8e-08 32.6 2.4 1.7 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 OAG14612.1 - 7.7e-08 32.3 0.1 1.8e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 OAG14612.1 - 5.6e-07 29.4 1.9 8.4e-07 28.8 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG14612.1 - 7.9e-06 25.8 1.9 1.5e-05 24.9 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG14612.1 - 1.1e-05 25.2 2.8 1.6e-05 24.7 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG14612.1 - 0.0012 18.9 0.5 0.0023 18.0 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG14612.1 - 0.0077 16.1 3.1 0.013 15.3 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAG14612.1 - 0.025 14.2 3.0 0.047 13.3 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAG14612.1 - 0.24 11.6 2.2 0.57 10.4 2.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OAG14612.1 - 0.24 11.6 4.3 0.47 10.6 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OAG14612.1 - 0.44 10.7 2.1 0.93 9.7 2.1 1.6 1 1 0 1 1 1 0 RING-variant domain DUF1137 PF06587.11 OAG14613.1 - 0.11 12.5 0.0 25 4.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1137) MAPEG PF01124.18 OAG14614.1 - 1e-16 61.0 1.9 9.1e-16 57.9 1.9 1.9 1 1 0 1 1 1 1 MAPEG family TMEM208_SND2 PF05620.11 OAG14614.1 - 0.28 10.9 2.0 2 8.2 0.4 2.0 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 F_bP_aldolase PF01116.20 OAG14615.1 - 1.2e-77 261.1 0.1 1.4e-77 260.9 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Hydrolase_6 PF13344.6 OAG14616.1 - 5.6e-30 103.5 0.0 1.2e-29 102.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG14616.1 - 1.1e-13 51.0 0.0 2.3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG14616.1 - 1.2e-12 48.6 0.1 1.9e-06 28.3 0.0 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG14616.1 - 8.3e-06 26.0 0.2 0.087 12.9 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Peptidase_M18 PF02127.15 OAG14617.1 - 9.6e-172 571.6 0.0 1.2e-171 571.3 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OAG14617.1 - 0.0034 16.5 0.1 1.6 7.7 0.1 3.1 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase WD40 PF00400.32 OAG14618.1 - 8.3e-25 86.6 7.2 0.0004 21.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14618.1 - 7.6e-14 51.8 6.7 2.2e-05 24.7 0.5 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG14618.1 - 1e-08 35.3 0.7 0.013 15.4 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DNA_primase_lrg PF04104.14 OAG14619.1 - 1e-83 280.8 0.0 2.7e-83 279.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit ArdA PF07275.11 OAG14619.1 - 0.24 12.0 0.7 0.85 10.2 0.1 2.1 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Lipase_GDSL_2 PF13472.6 OAG14620.1 - 1.4e-20 74.5 2.5 2.1e-20 73.9 2.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG14620.1 - 1.8e-07 31.4 0.3 3.2e-07 30.5 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank_2 PF12796.7 OAG14623.1 - 7.8e-68 225.1 0.0 1.3e-11 44.9 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG14623.1 - 9.4e-42 136.2 0.3 0.002 18.5 0.1 10.9 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 OAG14623.1 - 1.7e-37 127.3 1.2 2.2e-09 37.7 0.0 7.2 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG14623.1 - 3.6e-36 122.7 5.6 1.7e-05 25.0 0.0 9.6 3 3 7 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 OAG14623.1 - 2e-35 119.6 3.1 0.0067 16.8 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat VWA_3_C PF18571.1 OAG14623.1 - 0.013 15.3 2.8 67 3.5 0.0 5.6 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain PA-IL PF07828.12 OAG14623.1 - 0.13 12.3 0.0 4.8 7.2 0.0 2.5 1 1 1 2 2 2 0 PA-IL-like protein MFS_1 PF07690.16 OAG14624.1 - 9.9e-30 103.6 19.7 9.9e-30 103.6 19.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG14624.1 - 5.1e-08 32.6 2.1 1e-07 31.6 2.1 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB HpcH_HpaI PF03328.14 OAG14625.1 - 2.7e-30 105.1 0.0 4.4e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 OAG14625.1 - 0.0031 16.7 0.5 0.072 12.2 0.3 2.6 2 1 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain Fungal_trans PF04082.18 OAG14626.1 - 3e-12 46.1 0.1 6.1e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14626.1 - 2.4e-05 24.3 12.2 4.8e-05 23.4 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbN PF02468.15 OAG14626.1 - 0.22 11.4 0.6 0.44 10.4 0.1 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) 2-Hacid_dh_C PF02826.19 OAG14627.1 - 1.2e-44 151.9 0.0 1.8e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG14627.1 - 7e-19 67.8 0.0 7.6e-19 67.7 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans PF04082.18 OAG14628.1 - 6.3e-17 61.5 0.2 8.9e-17 61.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14628.1 - 3.7e-09 36.5 8.5 8.9e-09 35.3 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 OAG14628.1 - 3.7 8.0 8.3 0.41 11.0 3.3 2.0 2 0 0 2 2 2 0 Opy2 protein NAD_binding_4 PF07993.12 OAG14629.1 - 1.1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG14629.1 - 9.5e-05 22.0 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAG14630.1 - 4.5e-07 29.9 8.3 8.6e-07 29.0 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG14631.1 - 2.3e-44 151.8 48.3 2.3e-44 151.8 48.3 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG14631.1 - 2.7e-20 72.3 13.9 4e-20 71.8 13.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG14631.1 - 4.3e-16 58.8 7.9 4.3e-16 58.8 7.9 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG14631.1 - 0.011 16.1 0.4 0.011 16.1 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3522) OATP PF03137.20 OAG14631.1 - 8.7 4.5 13.6 53 1.9 13.6 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_6 PF12697.7 OAG14632.1 - 1e-06 29.5 0.1 1.7e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG14632.1 - 6.9e-06 25.9 0.0 6.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 OAG14632.1 - 7.7e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 OAG14632.1 - 2.3e-05 24.2 0.1 5.7e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OAG14632.1 - 0.0028 17.5 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 OAG14632.1 - 0.029 13.0 0.0 0.35 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OAG14632.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OAG14632.1 - 0.09 12.3 1.0 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAG14632.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mpp10 PF04006.12 OAG14633.1 - 3.4e-118 395.8 40.7 1.1e-117 394.0 40.7 1.7 1 1 0 1 1 1 1 Mpp10 protein MFS_1 PF07690.16 OAG14635.1 - 2.3e-12 46.6 55.9 8.8e-10 38.0 51.2 3.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF697 PF05128.12 OAG14635.1 - 0.088 12.5 2.1 0.43 10.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) tRNA-synt_1g PF09334.11 OAG14636.1 - 2.5e-153 510.5 0.4 3.5e-153 510.0 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAG14636.1 - 3.6e-07 28.8 8.4 1.4e-06 26.9 0.0 3.3 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG14636.1 - 0.0034 17.4 0.2 0.008 16.2 0.1 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG14636.1 - 0.036 13.4 0.0 0.036 13.4 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF1682 PF07946.14 OAG14636.1 - 0.089 12.0 5.3 0.14 11.3 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) BRF1 PF07741.13 OAG14636.1 - 3.3 8.1 12.1 9.3 6.7 12.1 1.8 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4407 PF14362.6 OAG14636.1 - 9.2 5.5 7.8 16 4.7 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Yae1_N PF09811.9 OAG14637.1 - 7.4e-10 38.4 1.6 1.1e-09 37.8 1.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Septin PF00735.18 OAG14638.1 - 2.5e-112 374.8 0.7 3e-112 374.5 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG14638.1 - 2.6e-08 33.9 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG14638.1 - 1.1e-05 25.4 0.3 7.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OAG14638.1 - 2.2e-05 23.9 0.0 6.9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 OAG14638.1 - 2.3e-05 24.0 0.3 0.0055 16.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG14638.1 - 0.0011 19.1 0.2 1.1 9.2 0.1 2.7 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 OAG14638.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG14638.1 - 0.0075 16.5 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAG14638.1 - 0.014 15.0 0.0 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 OAG14638.1 - 0.014 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 OAG14638.1 - 0.022 13.9 0.6 0.065 12.4 0.5 1.8 1 1 0 1 1 1 0 G-protein alpha subunit Ras PF00071.22 OAG14638.1 - 0.038 13.6 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 OAG14638.1 - 0.041 14.4 1.3 0.058 13.9 0.7 1.8 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 OAG14638.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OAG14638.1 - 0.079 13.4 0.1 0.17 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG14638.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 OAG14639.1 - 1e-11 44.9 0.9 1e-11 44.9 0.9 1.9 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 OAG14639.1 - 0.069 12.6 0.6 0.11 12.0 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain F-box-like_2 PF13013.6 OAG14639.1 - 0.1 12.6 0.3 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 F-box-like domain GRAB PF10375.9 OAG14640.1 - 1.2e-08 34.4 0.1 2.9e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.21 OAG14640.1 - 1.9e-05 24.4 44.7 0.075 12.6 8.3 3.2 1 1 2 3 3 3 2 Intermediate filament protein ZapB PF06005.12 OAG14640.1 - 0.00013 22.4 9.0 0.00013 22.4 9.0 5.5 3 2 1 4 4 4 2 Cell division protein ZapB Atg14 PF10186.9 OAG14640.1 - 0.00043 19.5 17.4 0.00043 19.5 17.4 3.0 2 1 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 OAG14640.1 - 0.00051 19.6 47.9 0.28 10.6 25.4 3.3 1 1 2 3 3 3 2 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 OAG14640.1 - 0.015 15.9 8.0 0.015 15.9 8.0 4.3 1 1 2 3 3 2 0 Syntaxin 6, N-terminal BST2 PF16716.5 OAG14640.1 - 0.023 15.3 41.6 0.06 13.9 8.6 5.1 3 2 1 4 4 4 0 Bone marrow stromal antigen 2 HOOK PF05622.12 OAG14640.1 - 0.071 11.3 48.4 0.71 7.9 37.5 3.6 1 1 3 4 4 4 0 HOOK protein EzrA PF06160.12 OAG14640.1 - 0.19 9.9 41.3 0.066 11.4 12.3 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 OAG14640.1 - 0.31 11.1 20.0 2.4 8.2 6.2 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OAG14640.1 - 0.34 11.1 28.4 1.8 8.8 1.9 3.9 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 OAG14640.1 - 0.57 10.4 0.1 0.57 10.4 0.1 4.8 5 1 1 6 6 6 0 Homeobox associated leucine zipper ATG16 PF08614.11 OAG14640.1 - 2.4 8.4 64.7 0.38 11.0 21.4 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.6 OAG14640.1 - 2.5 7.4 47.0 1.1 8.5 17.3 3.6 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAG14640.1 - 3.1 7.9 20.9 2.6 8.1 2.4 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) XhlA PF10779.9 OAG14640.1 - 3.2 8.0 28.0 0.13 12.5 1.5 5.1 3 1 2 5 5 5 0 Haemolysin XhlA TMEM191C PF15194.6 OAG14640.1 - 8.5 6.6 8.7 0.7 10.1 0.7 3.1 4 0 0 4 4 4 0 TMEM191C family Astacin PF01400.24 OAG14641.1 - 1.8e-08 34.2 1.8 8.4e-06 25.5 0.3 2.6 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OAG14641.1 - 0.00043 20.2 0.2 0.0029 17.5 0.1 2.2 2 1 1 3 3 3 1 Matrixin Reprolysin_5 PF13688.6 OAG14641.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAG14641.1 - 0.045 13.4 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAG14641.1 - 0.063 13.8 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 OAG14641.1 - 0.13 11.9 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 OAG14641.1 - 0.29 10.3 2.5 0.51 9.5 2.5 1.3 1 0 0 1 1 1 0 Met-zincin FAD_binding_3 PF01494.19 OAG14642.1 - 2.5e-34 119.1 0.0 4.3e-34 118.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG14642.1 - 5.3e-05 22.4 0.1 0.19 10.7 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 OAG14642.1 - 5.9e-05 22.8 0.0 0.0008 19.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAG14642.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG14642.1 - 0.068 12.4 0.1 0.24 10.6 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BPL_LplA_LipB PF03099.19 OAG14645.1 - 0.0014 18.5 0.0 0.0051 16.7 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 OAG14645.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF1289 PF06945.13 OAG14647.1 - 0.024 14.5 0.7 0.024 14.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) zf-C2H2_4 PF13894.6 OAG14647.1 - 0.21 12.5 0.2 0.21 12.5 0.2 4.8 3 1 1 4 4 4 0 C2H2-type zinc finger adh_short PF00106.25 OAG14648.1 - 1.6e-23 83.2 0.2 3.2e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14648.1 - 6.8e-14 52.0 0.1 4.1e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG14648.1 - 2.2e-07 31.0 0.1 3.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG14648.1 - 0.0037 16.4 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sds3 PF08598.11 OAG14648.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Sds3-like CTP_transf_like PF01467.26 OAG14649.1 - 0.0021 18.3 0.0 0.059 13.6 0.0 2.4 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF802 PF05650.11 OAG14650.1 - 0.073 13.6 0.6 0.28 11.7 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Totivirus_coat PF05518.11 OAG14651.1 - 6.3 4.7 12.6 8.4 4.3 12.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Methyltransf_23 PF13489.6 OAG14652.1 - 4e-19 69.1 0.0 7.6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG14652.1 - 3.4e-13 50.1 0.0 8.9e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG14652.1 - 1.7e-10 41.4 0.0 4.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG14652.1 - 1.3e-09 38.0 0.0 4.1e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG14652.1 - 8.1e-09 36.1 0.0 3e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG14652.1 - 0.00013 21.6 0.0 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 OAG14652.1 - 0.00058 20.0 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 OAG14652.1 - 0.0012 18.2 0.0 0.0029 16.9 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OAG14652.1 - 0.0038 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAG14652.1 - 0.013 14.8 0.0 0.079 12.3 0.0 2.1 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAG14652.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAG14652.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase WSC PF01822.19 OAG14654.1 - 1.8e-47 159.5 48.5 3.7e-18 65.5 12.9 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 OAG14654.1 - 8e-24 84.1 0.0 1e-22 80.5 0.0 2.5 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAG14654.1 - 6.1e-18 64.9 0.0 1.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) HAD_2 PF13419.6 OAG14655.1 - 1.7e-18 67.3 0.0 2.8e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG14655.1 - 3e-10 40.7 0.0 2.8e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG14655.1 - 5.5e-05 23.2 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG14655.1 - 0.0078 16.3 0.2 0.24 11.5 0.2 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Fructosamin_kin PF03881.14 OAG14656.1 - 5e-32 111.3 0.0 7.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG14656.1 - 0.00099 19.1 0.0 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family HET PF06985.11 OAG14658.1 - 1.6e-14 54.5 0.1 4.1e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CUE PF02845.16 OAG14658.1 - 0.0017 18.0 0.3 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 CUE domain Taeniidae_ag PF05596.11 OAG14658.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen TatD_DNase PF01026.21 OAG14659.1 - 2.1e-39 135.5 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Glyco_hydro_36 PF17167.4 OAG14660.1 - 1.2e-61 208.8 0.1 2.6e-61 207.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 OAG14660.1 - 3.2e-30 105.4 0.1 5.3e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 OAG14660.1 - 2.6e-05 23.6 0.1 7.1e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1380 PF07128.12 OAG14660.1 - 0.018 15.2 0.1 0.2 11.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1380) Glyco_hydro_65C PF03633.15 OAG14660.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain WD40 PF00400.32 OAG14661.1 - 3.9e-05 24.3 7.6 0.0033 18.2 0.1 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 OAG14661.1 - 0.00055 19.8 1.5 0.88 9.6 0.1 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PQQ PF01011.21 OAG14661.1 - 0.029 14.3 1.7 0.59 10.2 0.1 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat adh_short_C2 PF13561.6 OAG14662.1 - 4.2e-46 157.4 0.1 1.1e-40 139.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG14662.1 - 1e-44 152.4 0.1 1.3e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG14662.1 - 1.1e-14 54.8 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG14662.1 - 7.4e-06 25.6 0.1 3.2e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG14662.1 - 0.0048 16.3 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Meth_synt_2 PF01717.18 OAG14663.1 - 5.4e-153 509.0 0.0 3.7e-148 493.1 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG14663.1 - 7e-125 416.7 0.1 1.3e-117 392.8 0.0 3.2 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 OAG14663.1 - 3.8e-06 26.3 0.0 0.0046 16.2 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 OAG14663.1 - 0.9 9.4 3.1 0.48 10.2 0.2 2.2 2 0 0 2 2 2 0 Short C-terminal domain Kelch_4 PF13418.6 OAG14664.1 - 1.2e-05 25.2 3.0 0.47 10.5 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG14664.1 - 0.0046 16.9 1.7 0.23 11.5 0.0 3.3 4 0 0 4 4 4 1 Kelch motif MLANA PF14991.6 OAG14664.1 - 0.043 14.1 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Kelch_6 PF13964.6 OAG14664.1 - 0.083 13.2 10.1 1.1 9.6 0.1 4.6 6 0 0 6 6 6 0 Kelch motif SVIP PF15811.5 OAG14664.1 - 1.2 9.6 3.8 0.94 10.0 0.0 2.7 3 0 0 3 3 3 0 Small VCP/p97-interacting protein FAD_binding_4 PF01565.23 OAG14666.1 - 1.1e-25 90.0 0.2 1.6e-25 89.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG14666.1 - 0.016 15.3 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like MMR_HSR1 PF01926.23 OAG14667.1 - 8.6e-21 74.2 0.5 1.9e-09 37.6 0.0 3.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase AIG1 PF04548.16 OAG14667.1 - 2.2e-08 33.7 9.8 2.2e-05 23.9 0.0 3.4 3 0 0 3 3 2 2 AIG1 family FeoB_N PF02421.18 OAG14667.1 - 2.6e-08 33.5 0.4 0.0016 18.0 0.0 2.7 3 0 0 3 3 2 2 Ferrous iron transport protein B Septin PF00735.18 OAG14667.1 - 6.3e-07 29.0 0.0 0.051 12.8 0.0 2.8 2 0 0 2 2 2 2 Septin SRPRB PF09439.10 OAG14667.1 - 8.5e-07 28.6 0.1 0.0057 16.1 0.0 2.9 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG14667.1 - 2.2e-06 27.7 7.8 0.0016 18.3 0.2 3.4 3 2 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 OAG14667.1 - 0.00022 21.4 0.1 0.092 12.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG14667.1 - 0.00036 20.8 4.0 0.14 12.4 0.0 3.2 4 0 0 4 4 2 2 AAA domain NB-ARC PF00931.22 OAG14667.1 - 0.00086 18.6 6.8 0.32 10.1 0.0 4.0 4 0 0 4 4 4 2 NB-ARC domain ATP_bind_1 PF03029.17 OAG14667.1 - 0.0011 18.9 3.0 0.77 9.5 0.3 3.9 3 1 1 4 4 4 1 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 OAG14667.1 - 0.0013 18.5 0.5 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 OAG14667.1 - 0.0029 17.3 0.2 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG14667.1 - 0.009 16.0 0.2 2.4 8.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG14667.1 - 0.0094 16.5 10.8 0.69 10.4 0.0 4.2 4 0 0 4 4 4 2 ABC transporter SRP54 PF00448.22 OAG14667.1 - 0.0099 15.5 1.6 1.7 8.2 0.2 3.0 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain Urocanase PF01175.18 OAG14667.1 - 0.011 15.3 0.6 0.032 13.9 0.6 1.8 1 0 0 1 1 1 0 Urocanase Rossmann-like domain RNA_helicase PF00910.22 OAG14667.1 - 0.037 14.4 0.1 18 5.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 OAG14667.1 - 0.042 13.6 0.4 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OAG14667.1 - 0.048 14.2 11.5 0.54 10.8 0.0 4.2 4 1 0 4 4 2 0 AAA domain AAA_16 PF13191.6 OAG14667.1 - 0.048 14.0 2.2 11 6.4 0.0 3.2 3 0 0 3 3 2 0 AAA ATPase domain Arf PF00025.21 OAG14667.1 - 0.059 12.8 0.1 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 OAG14667.1 - 0.068 12.1 1.0 1.2 8.0 0.1 2.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 OAG14667.1 - 0.071 12.9 0.7 2 8.2 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 OAG14667.1 - 0.071 13.3 0.1 7.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 OAG14667.1 - 0.12 12.1 1.0 4 7.1 0.1 3.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 OAG14667.1 - 0.12 12.3 0.4 17 5.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Gtr1_RagA PF04670.12 OAG14667.1 - 0.2 11.0 2.8 0.81 9.0 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region IIGP PF05049.13 OAG14667.1 - 1.1 8.2 5.7 4 6.4 0.0 2.7 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 OAG14667.1 - 1.3 8.5 4.7 41 3.7 0.1 3.8 3 1 1 4 4 4 0 AAA domain Dynamin_N PF00350.23 OAG14667.1 - 6.8 6.7 31.4 2.5 8.2 0.0 7.1 4 4 2 6 6 4 0 Dynamin family AIG1 PF04548.16 OAG14668.1 - 3.1e-07 29.9 0.5 6.2e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OAG14668.1 - 7.1e-07 29.3 0.2 4.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Cep57_MT_bd PF06657.13 OAG14668.1 - 0.00062 20.2 10.0 0.5 10.9 0.1 3.4 3 0 0 3 3 3 2 Centrosome microtubule-binding domain of Cep57 RsgA_GTPase PF03193.16 OAG14668.1 - 0.0012 18.8 1.5 0.0086 16.0 0.3 2.5 2 0 0 2 2 2 1 RsgA GTPase ALMT PF11744.8 OAG14668.1 - 0.0014 17.5 4.6 0.0021 17.0 4.6 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter TPR_MLP1_2 PF07926.12 OAG14668.1 - 0.0025 17.9 5.9 0.0025 17.9 5.9 2.8 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 OAG14668.1 - 0.0041 17.0 11.4 0.0041 17.0 11.4 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 OAG14668.1 - 0.0071 16.4 4.7 0.0071 16.4 4.7 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zw10 PF06248.13 OAG14668.1 - 0.03 12.9 7.7 0.077 11.6 6.3 2.1 2 1 0 2 2 2 0 Centromere/kinetochore Zw10 DUF1664 PF07889.12 OAG14668.1 - 0.048 13.7 1.0 0.048 13.7 1.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) OmpH PF03938.14 OAG14668.1 - 0.058 13.7 10.0 0.23 11.8 2.0 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.23 OAG14668.1 - 0.097 12.7 6.7 0.65 10.0 0.0 3.5 2 2 1 3 3 3 0 Dynamin family YPEB PF14620.6 OAG14668.1 - 0.1 11.9 5.4 0.29 10.4 5.4 1.7 1 1 0 1 1 1 0 YpeB sporulation BLOC1_2 PF10046.9 OAG14668.1 - 0.12 12.7 3.1 0.22 11.9 1.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Viral_P18 PF04521.13 OAG14668.1 - 0.14 12.0 2.3 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein KxDL PF10241.9 OAG14668.1 - 0.16 12.3 7.2 2.6 8.4 2.8 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein Prefoldin PF02996.17 OAG14668.1 - 0.17 11.8 6.3 0.25 11.2 2.0 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF4510 PF14971.6 OAG14668.1 - 0.22 11.9 4.5 0.14 12.5 0.9 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4510) Fez1 PF06818.15 OAG14668.1 - 0.28 11.6 10.2 0.64 10.4 10.2 1.6 1 0 0 1 1 1 0 Fez1 ABC_tran_CTD PF16326.5 OAG14668.1 - 2.1 8.6 10.5 1.7 8.9 2.0 3.6 3 1 0 3 3 3 0 ABC transporter C-terminal domain PRKG1_interact PF15898.5 OAG14668.1 - 2.6 9.0 14.7 2 9.4 2.3 2.6 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 OAG14668.1 - 4.1 7.6 8.1 6.6 6.9 5.2 2.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 OAG14668.1 - 5.5 7.3 11.1 1.7 8.9 3.4 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Enkurin PF13864.6 OAG14668.1 - 9.2 6.8 10.9 2.6 8.6 3.6 2.6 1 1 0 2 2 2 0 Calmodulin-binding FlaC_arch PF05377.11 OAG14668.1 - 9.2 6.7 7.1 17 5.9 0.4 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LapA_dom PF06305.11 OAG14669.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pro-kuma_activ PF09286.11 OAG14670.1 - 6.8e-38 130.2 0.3 4.4e-37 127.5 0.0 2.3 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG14670.1 - 6e-09 35.6 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family zf-RAG1 PF10426.9 OAG14670.1 - 0.13 12.4 0.7 0.25 11.5 0.7 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain HSP20 PF00011.21 OAG14671.1 - 2.9e-15 56.2 0.6 7.1e-11 42.2 0.1 2.6 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG14671.1 - 0.0032 17.0 0.0 0.0073 15.8 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA MscS_TM PF12794.7 OAG14671.1 - 0.14 11.0 2.6 0.25 10.1 2.6 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ndc1_Nup PF09531.10 OAG14671.1 - 1.9 7.0 12.6 3.2 6.3 12.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pap_E4 PF02711.14 OAG14672.1 - 0.064 14.2 0.2 0.074 14.0 0.2 1.1 1 0 0 1 1 1 0 E4 protein Hamartin PF04388.12 OAG14672.1 - 0.81 8.3 4.8 0.87 8.2 4.8 1.0 1 0 0 1 1 1 0 Hamartin protein HET PF06985.11 OAG14674.1 - 6.9e-27 94.6 0.2 8.2e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAN_4 PF14295.6 OAG14675.1 - 0.0084 16.0 3.9 0.16 11.9 0.6 2.6 2 0 0 2 2 2 2 PAN domain Opiods_neuropep PF01160.18 OAG14675.1 - 5.2 7.3 6.1 5.2 7.2 0.1 3.1 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide MIP PF00230.20 OAG14676.1 - 5.6e-45 153.8 14.0 7.4e-45 153.4 14.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein F-box-like_2 PF13013.6 OAG14677.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Rtt106_N PF18215.1 OAG14677.1 - 0.17 11.7 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Proton_antipo_N PF00662.20 OAG14677.1 - 0.41 10.8 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 4HBT PF03061.22 OAG14679.1 - 0.018 15.4 0.2 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily MHYT PF03707.16 OAG14681.1 - 1.5e-11 44.3 16.1 1.6e-07 31.4 0.1 4.0 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat TM2 PF05154.16 OAG14681.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.9 4 0 0 4 4 4 0 TM2 domain WD40 PF00400.32 OAG14682.1 - 1.7e-35 120.4 7.9 5.1e-09 36.6 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14682.1 - 1.1e-13 51.3 1.2 0.015 15.6 0.0 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG14682.1 - 0.0022 17.1 0.7 0.045 12.8 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region Amidohydro_3 PF07969.11 OAG14682.1 - 0.0029 17.1 0.1 0.004 16.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family IKI3 PF04762.12 OAG14682.1 - 0.15 10.1 0.3 0.35 8.8 0.2 1.7 3 0 0 3 3 3 0 IKI3 family CTP_transf_like PF01467.26 OAG14683.1 - 2.9e-26 92.4 0.0 5.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Svs_4_5_6 PF17381.2 OAG14683.1 - 3.3 8.8 10.0 0.4 11.7 1.3 2.6 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 Clc-like PF07062.12 OAG14685.1 - 0.029 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Clc-like Tcp11 PF05794.13 OAG14686.1 - 4.7e-102 342.4 0.0 6.4e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 DUF3042 PF11240.8 OAG14687.1 - 0.16 12.0 0.2 3.9 7.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) ADH_N PF08240.12 OAG14688.1 - 2.2e-09 37.1 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG14688.1 - 2.3e-09 37.3 0.1 3.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG14688.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PHP_C PF13263.6 OAG14688.1 - 0.027 14.2 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 PHP-associated Eno-Rase_NADH_b PF12242.8 OAG14688.1 - 0.032 14.0 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNMT1-RFD PF12047.8 OAG14688.1 - 0.041 13.9 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain DJ-1_PfpI PF01965.24 OAG14690.1 - 6.4e-19 68.3 0.0 1.5e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 OAG14690.1 - 0.0016 18.3 0.1 0.0029 17.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Tautomerase_3 PF14832.6 OAG14692.1 - 4.5e-46 156.5 0.0 5.3e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 OAG14692.1 - 7e-05 22.7 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 Tautomerase enzyme IRF PF00605.17 OAG14692.1 - 0.036 14.4 0.2 0.07 13.4 0.2 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor NmrA PF05368.13 OAG14693.1 - 2.4e-22 79.6 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14693.1 - 1.9e-09 37.7 0.1 6.2e-09 36.0 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG14693.1 - 0.001 18.6 0.1 0.0044 16.5 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 OAG14693.1 - 0.0024 17.9 0.2 0.054 13.5 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain CBS PF00571.28 OAG14693.1 - 0.0042 17.5 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 CBS domain Semialdhyde_dh PF01118.24 OAG14693.1 - 0.0097 16.3 0.3 0.17 12.3 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain LpxI_N PF17930.1 OAG14693.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 LpxI N-terminal domain CbiJ PF02571.14 OAG14693.1 - 0.06 12.8 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_2 PF03446.15 OAG14693.1 - 0.068 13.3 0.0 0.4 10.8 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.19 OAG14693.1 - 0.2 12.3 0.9 0.76 10.5 0.9 2.0 1 1 0 1 1 1 0 CoA binding domain HET PF06985.11 OAG14694.1 - 1.7e-05 25.2 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG14695.1 - 6.2e-33 114.2 0.1 1.1e-32 113.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Protoglobin PF11563.8 OAG14696.1 - 8e-60 201.3 0.1 1e-59 201.0 0.1 1.1 1 0 0 1 1 1 1 Protoglobin DUF1242 PF06842.12 OAG14698.1 - 9.4e-13 47.7 0.5 1.2e-12 47.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 OAG14699.1 - 1.1e-24 86.2 0.2 1.4e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 OAG14699.1 - 0.00011 22.5 1.2 0.00014 22.1 0.3 1.6 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 OAG14699.1 - 0.00062 19.9 0.1 0.00076 19.6 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG14699.1 - 0.0064 16.8 0.6 0.011 16.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAG14699.1 - 0.022 14.9 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG14699.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 OAG14699.1 - 0.11 13.0 0.4 0.21 12.1 0.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Exo_endo_phos_2 PF14529.6 OAG14700.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1996 PF09362.10 OAG14701.1 - 3.2e-43 148.4 0.4 4e-43 148.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 OAG14702.1 - 7.8e-21 75.0 0.0 1.2e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GCP5-Mod21 PF14609.6 OAG14703.1 - 0.058 11.7 0.7 0.064 11.6 0.7 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Pectinesterase PF01095.19 OAG14704.1 - 3.9e-48 163.7 2.5 5.2e-48 163.3 2.5 1.0 1 0 0 1 1 1 1 Pectinesterase ALAD PF00490.21 OAG14707.1 - 7.7e-121 403.1 0.0 9e-121 402.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase BCS1_N PF08740.11 OAG14708.1 - 6.8e-32 111.0 0.6 1.6e-31 109.7 0.0 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 OAG14708.1 - 1.1e-16 61.5 0.0 6.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG14708.1 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG14708.1 - 0.02 15.3 0.1 0.063 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OAG14708.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 OAG14708.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAG14708.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.5 1 1 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 OAG14708.1 - 0.44 9.2 5.2 0.63 8.7 5.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 OAG14708.1 - 0.45 9.7 2.3 0.91 8.7 2.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 OAG14708.1 - 8.1 3.4 10.6 13 2.8 10.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HET PF06985.11 OAG14709.1 - 6.7e-25 88.2 0.0 9.2e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5412 PF17428.2 OAG14709.1 - 0.032 14.1 0.9 0.063 13.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5412) DUF3176 PF11374.8 OAG14711.1 - 1.6e-28 99.0 0.4 3.9e-28 97.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MFS_1 PF07690.16 OAG14712.1 - 3e-35 121.8 33.0 4.6e-35 121.2 33.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14712.1 - 3.3e-10 39.4 6.2 3.3e-10 39.4 6.2 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter DUF4271 PF14093.6 OAG14712.1 - 0.0053 16.7 0.9 0.0053 16.7 0.9 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF4271) 2OG-FeII_Oxy PF03171.20 OAG14713.1 - 1.9e-15 57.2 0.0 1.5e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG14713.1 - 8.7e-14 52.3 0.0 1.4e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Clr5 PF14420.6 OAG14714.1 - 1.2e-11 44.6 2.3 2.9e-11 43.4 2.3 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAG14714.1 - 1.4e-05 25.2 3.9 2.7e-05 24.4 0.7 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG14714.1 - 0.0014 19.2 2.9 8.2 7.5 0.1 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG14714.1 - 0.035 14.0 1.9 0.16 11.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TraI_2_C PF07515.11 OAG14714.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term DUF3861 PF12977.7 OAG14714.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) TPR_2 PF07719.17 OAG14714.1 - 0.13 12.4 2.3 12 6.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.6 OAG14714.1 - 0.18 12.1 1.6 14 6.1 0.0 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TPR_6 PF13174.6 OAG14714.1 - 0.84 10.4 4.6 31 5.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HET PF06985.11 OAG14716.1 - 5.6e-37 127.3 0.1 6.5e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stealth_CR4 PF17103.5 OAG14716.1 - 0.0048 16.8 0.2 0.44 10.5 0.0 2.6 3 0 0 3 3 3 2 Stealth protein CR4, conserved region 4 Transferase PF02458.15 OAG14717.1 - 5.1e-24 84.7 0.0 3.8e-22 78.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family Pkinase_Tyr PF07714.17 OAG14717.1 - 0.04 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RRM_1 PF00076.22 OAG14718.1 - 1.3e-11 44.2 0.2 0.00037 20.2 0.0 4.6 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAG14718.1 - 2.3e-05 24.3 0.1 0.042 13.9 0.1 2.7 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_5 PF13893.6 OAG14718.1 - 0.047 13.3 0.0 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 OAG14720.1 - 7.2e-60 202.7 0.0 9.6e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG14720.1 - 9.3e-15 55.4 0.0 2.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Herpes_UL47 PF03362.13 OAG14720.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein NMO PF03060.15 OAG14720.1 - 0.18 11.1 0.3 0.36 10.2 0.3 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DUF1658 PF07871.11 OAG14721.1 - 0.0055 16.6 7.8 0.013 15.4 0.4 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1658) Transferase PF02458.15 OAG14722.1 - 4.4e-22 78.4 0.0 6e-14 51.5 0.0 2.5 2 1 0 2 2 2 2 Transferase family ACOX PF01756.19 OAG14723.1 - 1.8e-43 148.2 0.1 6e-43 146.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG14723.1 - 2.1e-25 89.7 2.4 5.3e-25 88.4 2.4 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG14723.1 - 4.4e-08 33.2 0.0 3.3e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG14723.1 - 0.095 12.9 0.9 0.96 9.6 0.6 2.5 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 OAG14724.1 - 1.8e-08 34.3 13.7 3.2e-08 33.6 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DER1 PF04511.15 OAG14725.1 - 0.05 13.5 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 Der1-like family Acetyltransf_1 PF00583.25 OAG14726.1 - 3.3e-12 46.7 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG14726.1 - 3.2e-08 33.4 0.1 4.8e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OAG14726.1 - 7.2e-08 32.4 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG14726.1 - 1.4e-05 25.5 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG14726.1 - 0.0048 17.0 0.1 0.0097 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAG14726.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 Putative acetyl-transferase Glyco_hydro_130 PF04041.13 OAG14726.1 - 0.018 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase CTP_transf_like PF01467.26 OAG14728.1 - 1.8e-23 83.4 0.0 3e-22 79.4 0.0 2.6 2 1 1 3 3 3 1 Cytidylyltransferase-like Morc6_S5 PF17942.1 OAG14729.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like Glyco_hydro_6 PF01341.17 OAG14731.1 - 2.6e-96 323.0 0.1 3.3e-96 322.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 But2 PF09792.9 OAG14733.1 - 7.6e-55 185.2 0.7 7.6e-55 185.2 0.7 2.5 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain BCSC_C PF05420.11 OAG14733.1 - 0.04 13.1 0.2 2.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Cellulose synthase operon protein C C-terminus (BCSC_C) DUF5412 PF17428.2 OAG14733.1 - 0.22 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5412) TMEM132D_C PF15706.5 OAG14734.1 - 0.19 11.5 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MIP PF00230.20 OAG14735.1 - 5.8e-44 150.5 16.3 7.6e-44 150.1 16.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein EB1 PF03271.17 OAG14737.1 - 6.1e-18 64.8 1.5 6.1e-18 64.8 1.5 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 OAG14737.1 - 1.2e-07 31.8 0.8 2.2e-07 31.0 0.6 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OAG14737.1 - 0.011 15.9 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Syja_N PF02383.18 OAG14737.1 - 0.067 12.5 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Lipase_GDSL_2 PF13472.6 OAG14738.1 - 2.8e-14 53.9 0.3 3.9e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG14738.1 - 3.6e-11 43.4 0.1 4.8e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 OAG14738.1 - 0.00051 19.4 0.0 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 OAG14738.1 - 0.0068 16.6 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NinE PF05322.11 OAG14738.1 - 0.045 13.7 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 NINE Protein DLH PF01738.18 OAG14739.1 - 2.3e-28 99.2 0.0 2.9e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG14739.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3425 PF11905.8 OAG14740.1 - 3.8e-19 68.9 0.3 6.4e-19 68.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Scytalone_dh PF02982.14 OAG14741.1 - 1.6e-13 50.8 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 OAG14741.1 - 4.6e-10 39.7 0.0 5.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Pertussis_S1 PF02917.14 OAG14741.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Glyco_hydro_61 PF03443.14 OAG14743.1 - 3.1e-55 187.3 0.0 3.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.7 OAG14744.1 - 9.1e-05 23.0 0.1 0.13 12.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG14744.1 - 0.0024 18.2 0.4 15 6.6 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 OAG14744.1 - 0.011 16.1 1.5 21 5.8 0.2 4.4 4 1 0 4 4 4 0 Ankyrin repeat PX PF00787.24 OAG14745.1 - 1.2e-14 54.2 0.0 2.9e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 PX domain 2OG-FeII_Oxy PF03171.20 OAG14746.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-RING_2 PF13639.6 OAG14747.1 - 0.00035 20.8 1.9 0.00042 20.6 1.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG14747.1 - 0.00089 19.2 0.9 0.0011 18.9 0.9 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG14747.1 - 0.0056 16.9 0.9 0.0067 16.7 0.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG14747.1 - 0.013 15.3 1.9 0.035 13.9 2.1 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG14747.1 - 0.035 14.1 2.2 0.044 13.8 2.2 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 OAG14747.1 - 0.26 11.1 2.7 0.33 10.7 2.7 1.2 1 0 0 1 1 1 0 RING-like zinc finger Abhydrolase_6 PF12697.7 OAG14748.1 - 8e-16 59.3 0.3 1.2e-15 58.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG14748.1 - 5.4e-15 55.7 0.2 3.5e-09 36.7 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14748.1 - 5.5e-07 29.1 0.2 2e-06 27.3 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 OAG14749.1 - 8.2e-25 87.6 0.0 9.3e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG14749.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG14749.1 - 0.16 11.4 0.1 0.9 9.0 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family NACHT PF05729.12 OAG14750.1 - 1e-08 35.3 2.0 2.7e-07 30.7 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 OAG14750.1 - 8e-08 32.8 0.0 7.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG14750.1 - 0.00025 21.3 0.2 0.0021 18.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain SesA PF17107.5 OAG14750.1 - 0.00075 19.7 0.0 0.0034 17.6 0.0 2.3 2 1 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran PF00005.27 OAG14750.1 - 0.0012 19.3 0.1 0.0048 17.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 OAG14750.1 - 0.0034 17.6 0.3 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAG14750.1 - 0.011 16.3 2.6 0.12 12.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Med30 PF11315.8 OAG14750.1 - 0.013 15.7 0.5 0.17 12.0 0.0 2.7 2 1 0 3 3 3 0 Mediator complex subunit 30 RNA_helicase PF00910.22 OAG14750.1 - 0.015 15.7 1.5 0.025 15.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OAG14750.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG14750.1 - 0.027 13.7 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 OAG14750.1 - 0.03 14.9 0.1 0.32 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG14750.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAG14750.1 - 0.048 14.1 0.0 0.63 10.5 0.0 2.7 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAG14750.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 OAG14750.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 OAG14750.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Iron_transport PF10634.9 OAG14750.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Fe2+ transport protein Ploopntkinase3 PF18751.1 OAG14750.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 UPF0184 PF03670.13 OAG14750.1 - 0.57 10.6 6.2 0.21 12.0 1.5 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) HET PF06985.11 OAG14751.1 - 1.3e-21 77.5 0.0 2.6e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5581 PF17744.1 OAG14751.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5581) NACHT PF05729.12 OAG14752.1 - 5.6e-06 26.4 0.1 1.8e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG14752.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG14752.1 - 0.012 16.0 0.0 0.048 14.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG14752.1 - 0.025 14.9 0.1 0.2 11.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 OAG14752.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea UTP25 PF06862.12 OAG14753.1 - 2.8e-181 603.4 0.1 3.6e-181 603.1 0.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 JAB PF01398.21 OAG14754.1 - 2.9e-21 75.6 0.0 4.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAG14754.1 - 3.9e-21 75.5 0.7 7.5e-21 74.7 0.7 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 OAG14754.1 - 7.3e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) FlaC_arch PF05377.11 OAG14754.1 - 0.12 12.8 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DZR PF12773.7 OAG14755.1 - 0.00082 19.4 3.9 0.002 18.1 0.7 2.2 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 OAG14755.1 - 0.011 15.1 7.9 0.11 12.0 4.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OAG14755.1 - 0.039 13.7 9.2 0.11 12.3 4.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 OAG14755.1 - 0.096 12.4 9.1 7.2 6.4 0.4 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 OAG14755.1 - 0.17 12.6 6.9 1.5 9.6 7.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 OAG14755.1 - 2.2 8.3 5.8 2.1 8.4 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF35_N PF12172.8 OAG14755.1 - 3 7.8 7.6 18 5.3 0.4 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TF_Zn_Ribbon PF08271.12 OAG14755.1 - 7.6 6.1 11.1 2.8 7.5 0.3 3.1 2 1 1 3 3 3 0 TFIIB zinc-binding Glyco_hydro_28 PF00295.17 OAG14756.1 - 2e-81 273.6 17.6 2.5e-81 273.3 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.16 OAG14758.1 - 2.6e-35 122.0 39.0 2.6e-35 122.0 39.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF373 PF04123.13 OAG14759.1 - 0.17 11.3 6.0 0.083 12.3 3.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) LRR_4 PF12799.7 OAG14760.1 - 0.033 14.6 3.2 29 5.2 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Acyl-CoA_dh_1 PF00441.24 OAG14761.1 - 3.2e-31 108.6 4.0 6.2e-31 107.6 4.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG14761.1 - 9.2e-21 73.9 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG14761.1 - 1.3e-18 67.7 0.0 3e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG14761.1 - 6.6e-14 52.3 8.0 3.2e-13 50.1 5.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3405 PF11885.8 OAG14762.1 - 3.4e-228 758.4 3.4 4.1e-228 758.2 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) adh_short_C2 PF13561.6 OAG14763.1 - 1.1e-53 182.2 4.5 3.7e-53 180.5 4.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG14763.1 - 2e-32 112.2 3.6 1.7e-31 109.2 3.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG14763.1 - 5.1e-05 23.2 0.6 0.00055 19.9 0.1 2.1 1 1 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 OAG14763.1 - 0.0013 18.1 0.1 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LIP PF03583.14 OAG14765.1 - 9.2e-76 254.9 0.2 1.2e-75 254.5 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase DUF2235 PF09994.9 OAG14766.1 - 1.5e-56 191.9 0.0 1.5e-56 191.9 0.0 2.2 3 1 0 3 3 3 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) GFA PF04828.14 OAG14767.1 - 2.3e-20 72.7 0.5 3.7e-20 72.1 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme EspG PF06872.11 OAG14767.1 - 0.041 12.4 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 EspG protein Rpr2 PF04032.16 OAG14767.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.1 1 1 2 3 3 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NapB PF03892.14 OAG14767.1 - 1.5 8.9 4.3 5.7 7.0 4.3 1.8 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Fungal_trans PF04082.18 OAG14768.1 - 3.7e-09 36.0 0.6 9.9e-09 34.6 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14768.1 - 5.7e-06 26.4 14.0 9.8e-06 25.6 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpaB PF03241.13 OAG14768.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal DLH PF01738.18 OAG14769.1 - 9.5e-07 28.6 0.1 5.6e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAG14769.1 - 1.7e-05 25.6 0.2 2.2e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG14769.1 - 0.00015 21.5 0.0 0.00091 18.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14769.1 - 0.00042 19.7 0.0 0.82 8.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG14769.1 - 0.0066 15.9 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG14769.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 OAG14769.1 - 0.02 13.6 0.1 0.04 12.6 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 OAG14769.1 - 0.023 13.5 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 OAG14769.1 - 0.093 12.3 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) adh_short PF00106.25 OAG14771.1 - 6e-35 120.5 0.0 7.6e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG14771.1 - 2.5e-22 79.6 0.1 3.4e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG14771.1 - 4.5e-05 23.4 0.3 0.00011 22.1 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG14771.1 - 6e-05 23.0 0.0 8.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG14771.1 - 0.0041 16.5 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 OAG14771.1 - 0.0056 16.3 0.2 0.036 13.6 0.3 1.9 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 OAG14771.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2985 PF11204.8 OAG14772.1 - 1.1e-36 124.8 1.1 2.4e-36 123.8 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Glyco_transf_28 PF03033.20 OAG14773.1 - 9.3e-19 67.8 0.0 3.9e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG14773.1 - 4.7e-06 25.7 0.1 8.4e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG14773.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain p450 PF00067.22 OAG14774.1 - 5.8e-57 193.5 0.0 8.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PEPCK_GTP PF00821.18 OAG14774.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Aspzincin_M35 PF14521.6 OAG14775.1 - 1.6e-36 126.0 4.3 4.2e-36 124.7 4.3 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 OAG14775.1 - 3.8e-31 108.3 18.7 1.8e-30 106.1 18.7 1.8 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 OAG14775.1 - 0.0015 18.1 1.5 0.0015 18.1 1.5 2.0 2 0 0 2 2 2 1 Putative peptidase family GST_N_5 PF18485.1 OAG14775.1 - 0.034 14.5 0.2 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain IL7 PF01415.16 OAG14775.1 - 0.071 13.1 0.3 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 Interleukin 7/9 family COesterase PF00135.28 OAG14776.1 - 4.5e-66 223.8 0.0 5.8e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG14776.1 - 2.6e-11 43.8 0.8 1e-09 38.5 0.5 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG14776.1 - 0.0024 17.5 1.1 0.012 15.3 1.1 1.9 1 1 0 1 1 1 1 Putative esterase zf-His_Me_endon PF05551.11 OAG14777.1 - 0.0011 19.2 0.1 0.0014 18.8 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease SBP_bac_3 PF00497.20 OAG14778.1 - 6.9e-30 104.1 0.1 1.3e-29 103.2 0.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Abhydrolase_6 PF12697.7 OAG14779.1 - 2.2e-12 48.1 6.2 3.6e-12 47.4 6.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG14779.1 - 3.9e-12 46.4 1.1 3.9e-12 46.4 1.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14779.1 - 2.2e-05 23.9 0.2 3.2e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG14779.1 - 3e-05 24.3 0.4 4.6e-05 23.7 0.1 1.4 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 OAG14779.1 - 0.0022 17.7 0.5 0.0034 17.1 0.5 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 OAG14779.1 - 0.0034 17.2 0.3 0.0046 16.8 0.3 1.4 1 1 0 1 1 1 1 Lipase (class 3) TRP PF06011.12 OAG14781.1 - 6.5e-142 473.2 14.9 8.2e-142 472.9 14.9 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG14781.1 - 3.3e-38 131.2 0.1 8.9e-38 129.8 0.0 1.8 2 0 0 2 2 2 1 ML-like domain ETRAMP PF09716.10 OAG14781.1 - 2.5 8.2 5.3 0.96 9.6 0.0 2.9 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 OAG14781.1 - 4.6 8.2 0.0 4.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_cc PF11790.8 OAG14783.1 - 1e-75 254.4 1.8 1.4e-75 253.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Rhodanese_C PF12368.8 OAG14784.1 - 0.0015 18.8 4.2 0.13 12.6 0.5 2.7 2 0 0 2 2 2 2 Rhodanase C-terminal C1_2 PF03107.16 OAG14784.1 - 0.0045 17.3 3.7 0.0045 17.3 3.7 2.5 2 0 0 2 2 2 1 C1 domain zf-HC5HC2H PF13771.6 OAG14784.1 - 0.95 9.8 7.1 0.21 11.9 2.7 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain Lipase_3 PF01764.25 OAG14785.1 - 7.9e-16 58.2 0.0 1.4e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG14785.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family CorA PF01544.18 OAG14786.1 - 0.001 18.5 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MOLO1 PF17175.4 OAG14787.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 Glyco_hydro81C PF17652.1 OAG14789.1 - 1.1e-159 531.4 6.9 1.4e-159 531.0 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAG14789.1 - 2.7e-99 332.4 0.1 4e-99 331.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain WW PF00397.26 OAG14790.1 - 0.00012 22.1 0.5 0.00012 22.1 0.5 2.4 3 0 0 3 3 3 1 WW domain DASH_Spc34 PF08657.10 OAG14791.1 - 2.1e-44 152.3 0.0 6.9e-22 78.5 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Tropomyosin_1 PF12718.7 OAG14791.1 - 0.0035 17.5 8.7 0.0062 16.7 8.7 1.3 1 0 0 1 1 1 1 Tropomyosin like DegS PF05384.11 OAG14791.1 - 0.0091 15.5 5.1 0.014 14.9 5.1 1.2 1 0 0 1 1 1 1 Sensor protein DegS DUF3584 PF12128.8 OAG14791.1 - 0.031 11.8 4.5 0.039 11.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMCO5 PF14992.6 OAG14791.1 - 0.051 13.1 2.0 0.067 12.8 2.0 1.3 1 0 0 1 1 1 0 TMCO5 family DASH_Spc19 PF08287.11 OAG14791.1 - 0.088 12.7 3.3 0.13 12.1 3.3 1.2 1 0 0 1 1 1 0 Spc19 Spectrin PF00435.21 OAG14791.1 - 0.12 12.9 3.0 4.5 7.8 1.7 2.3 1 1 0 2 2 2 0 Spectrin repeat Rpn3_C PF08375.11 OAG14792.1 - 3.4e-27 94.7 1.2 1.2e-26 92.9 1.4 1.8 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAG14792.1 - 1e-22 80.6 1.3 1.2e-21 77.2 0.1 2.8 3 0 0 3 3 3 1 PCI domain Sigma70_r1_2 PF00140.20 OAG14792.1 - 1.6 8.8 4.7 1.6 8.8 2.0 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Ank_2 PF12796.7 OAG14793.1 - 9.8e-26 90.2 5.6 3.2e-09 37.3 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG14793.1 - 2.8e-21 75.3 0.3 1.5e-06 28.4 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG14793.1 - 1.4e-18 67.0 2.7 4.1e-09 36.8 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG14793.1 - 3.1e-15 54.7 5.0 0.00069 19.9 0.1 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OAG14793.1 - 2.4e-11 43.5 6.4 0.0019 18.6 0.3 5.1 5 0 0 5 5 5 4 Ankyrin repeat SPATIAL PF15256.6 OAG14794.1 - 0.019 15.3 0.2 0.026 14.9 0.2 1.2 1 0 0 1 1 1 0 SPATIAL Drf_FH1 PF06346.12 OAG14794.1 - 0.18 11.5 11.1 0.29 10.8 11.1 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 DWNN PF08783.11 OAG14795.1 - 3.5e-25 88.1 0.1 6.8e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAG14795.1 - 1.1e-11 44.3 5.2 2.1e-11 43.4 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 OAG14795.1 - 0.00012 21.9 6.3 0.00012 21.9 6.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG14795.1 - 0.0015 18.5 4.7 0.0035 17.3 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG14795.1 - 0.0035 17.6 5.5 0.0077 16.5 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 OAG14795.1 - 0.0078 16.0 2.1 0.018 14.9 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OAG14795.1 - 0.029 14.5 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 1 0 U-box domain zf-CCHC PF00098.23 OAG14795.1 - 0.045 13.8 0.5 0.13 12.4 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 OAG14795.1 - 0.047 12.0 2.0 0.072 11.4 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-RING_4 PF14570.6 OAG14795.1 - 0.049 13.4 5.1 0.14 12.0 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG14795.1 - 0.066 13.4 7.2 0.15 12.2 7.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG14795.1 - 0.11 12.4 5.9 0.24 11.3 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 OAG14795.1 - 0.16 12.1 3.8 0.42 10.7 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) eIF3g PF12353.8 OAG14795.1 - 0.16 12.3 5.8 1 9.7 0.1 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G GREB1 PF15782.5 OAG14795.1 - 2.1 5.4 7.0 2.7 5.0 7.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FSA_C PF10479.9 OAG14795.1 - 2.2 6.3 9.5 3.3 5.7 9.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 OAG14795.1 - 6.8 4.5 7.0 0.26 9.2 1.3 1.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.7 OAG14795.1 - 8.9 4.3 6.3 13 3.7 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PDZ_1 PF12812.7 OAG14796.1 - 1.9e-60 200.8 0.0 2.4e-36 123.6 0.0 2.8 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 OAG14796.1 - 2.4e-25 90.2 0.4 1.9e-21 77.5 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 OAG14796.1 - 2e-13 50.5 0.8 3.6e-06 27.2 0.1 4.0 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 OAG14796.1 - 4e-12 45.8 0.9 8.8e-06 25.5 0.4 4.7 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 OAG14796.1 - 4.9e-10 39.6 0.0 4.1e-05 23.8 0.0 3.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 OAG14796.1 - 7e-05 22.7 0.0 0.00026 20.9 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 OAG14796.1 - 0.0012 18.8 0.6 0.22 11.5 0.1 3.3 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 OAG14796.1 - 0.12 11.0 0.1 0.23 10.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 zf-Di19 PF05605.12 OAG14797.1 - 0.15 12.4 0.4 0.41 11.0 0.3 1.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CutC PF03932.14 OAG14799.1 - 2e-61 207.0 0.0 2.4e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 CutC family Synuclein PF01387.17 OAG14800.1 - 0.14 12.4 7.5 0.25 11.6 7.5 1.3 1 0 0 1 1 1 0 Synuclein Fungal_trans_2 PF11951.8 OAG14802.1 - 4.1e-10 39.0 0.1 1.1e-06 27.8 0.0 2.2 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14802.1 - 2.3e-06 27.6 10.5 4.8e-06 26.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TUTF7_u4 PF16631.5 OAG14803.1 - 0.098 13.3 0.6 0.13 12.9 0.6 1.0 1 0 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 p450 PF00067.22 OAG14804.1 - 5.4e-72 243.0 0.0 7.1e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Suppressor_APC PF11414.8 OAG14804.1 - 0.27 11.3 0.9 1.1 9.4 0.1 2.3 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein HET PF06985.11 OAG14805.1 - 5.4e-31 107.9 2.3 1.1e-30 106.9 2.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RP-C_C PF11800.8 OAG14806.1 - 0.048 13.7 0.6 0.073 13.2 0.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DRIM PF07539.12 OAG14807.1 - 4.5e-187 623.2 0.4 4.5e-187 623.2 0.4 3.9 5 1 0 5 5 5 1 Down-regulated in metastasis DNA_ligase_A_N PF04675.14 OAG14807.1 - 0.0019 18.5 1.5 15 5.9 0.1 4.1 3 0 0 3 3 3 2 DNA ligase N terminus MMS19_C PF12460.8 OAG14807.1 - 0.0073 15.5 1.7 3.5 6.7 0.1 4.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 OAG14807.1 - 0.0095 16.3 1.4 1.1 9.7 0.2 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OAG14807.1 - 0.017 15.3 5.4 71 4.1 0.0 7.3 8 0 0 8 8 8 0 HEAT repeat HD PF01966.22 OAG14807.1 - 0.069 13.4 1.2 1.1 9.5 1.9 2.7 2 0 0 2 2 2 0 HD domain CwfJ_C_1 PF04677.15 OAG14808.1 - 9.6e-22 77.1 0.0 2.7e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAG14808.1 - 1.9e-16 60.7 2.5 4.5e-16 59.5 2.5 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.28 OAG14808.1 - 0.01 16.4 0.0 0.033 14.7 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DUF1524 PF07510.11 OAG14809.1 - 1.4e-08 34.7 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 OAG14809.1 - 0.088 12.7 1.2 0.28 11.1 0.3 2.2 2 1 0 2 2 2 0 HNH endonuclease 120_Rick_ant PF12574.8 OAG14809.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.24 OAG14810.1 - 1.5e-68 231.7 20.8 1.8e-68 231.5 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG14810.1 - 7.1e-13 48.2 38.0 3.4e-12 46.0 33.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG14810.1 - 0.00046 19.2 9.3 0.00069 18.6 2.0 2.3 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 OAG14810.1 - 0.0074 14.9 24.0 0.013 14.1 5.8 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF1654 PF07867.11 OAG14811.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Gti1_Pac2 PF09729.9 OAG14812.1 - 1.4e-44 152.3 5.4 9.2e-38 130.1 0.2 3.0 2 1 1 3 3 3 2 Gti1/Pac2 family MFS_1 PF07690.16 OAG14813.1 - 1.5e-31 109.6 27.4 2.3e-31 109.0 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG14813.1 - 3.5 7.4 5.1 17 5.2 0.6 3.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Epimerase PF01370.21 OAG14814.1 - 2.6e-13 50.0 0.0 1.8e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG14814.1 - 3.9e-13 49.0 0.0 9.7e-13 47.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG14814.1 - 5.9e-11 42.3 0.0 8.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG14814.1 - 5.4e-10 39.5 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG14814.1 - 1.9e-07 30.5 0.0 2.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG14814.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAG14814.1 - 0.0013 18.0 0.1 0.016 14.4 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 OAG14814.1 - 0.0027 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG14814.1 - 0.0051 16.7 0.1 0.048 13.6 0.1 2.4 2 1 0 2 2 2 1 KR domain Zn_clus PF00172.18 OAG14815.1 - 3.8e-07 30.1 10.0 6.6e-07 29.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YihI PF04220.12 OAG14815.1 - 0.12 12.1 0.5 0.2 11.4 0.5 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) ADH_zinc_N PF00107.26 OAG14816.1 - 3.6e-09 36.7 1.0 8.4e-09 35.5 1.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG14816.1 - 6.5e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG14816.1 - 0.011 16.8 0.0 0.022 15.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.22 OAG14817.1 - 1.6e-18 66.2 0.9 3.2e-18 65.3 0.4 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG14817.1 - 2.4e-05 23.9 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG14817.1 - 0.067 13.1 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif JmjC PF02373.22 OAG14818.1 - 1.4e-08 35.2 0.0 2.1e-07 31.4 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAG14818.1 - 2e-08 34.2 0.0 7.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 OAG14818.1 - 4.7e-08 32.8 6.9 4.7e-08 32.8 6.9 2.3 2 0 0 2 2 2 1 PHD-finger JHD PF17811.1 OAG14818.1 - 1e-06 29.2 1.9 1.3e-06 28.9 0.6 1.8 2 0 0 2 2 2 1 Jumonji helical domain Dickkopf_N PF04706.12 OAG14818.1 - 3 8.4 11.5 2.8 8.5 0.6 3.0 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region zf-PHD-like PF15446.6 OAG14818.1 - 3.1 7.4 7.1 0.54 9.9 2.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Proteasome PF00227.26 OAG14819.1 - 1.2e-47 161.8 0.2 1.5e-47 161.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit p450 PF00067.22 OAG14821.1 - 1e-64 219.0 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 K_trans PF02705.16 OAG14823.1 - 1.2e-182 608.2 17.8 1.5e-182 607.9 17.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter TPPK_C PF12555.8 OAG14823.1 - 7.6 6.7 10.5 1.5 9.0 2.7 3.5 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DnaJ PF00226.31 OAG14824.1 - 2e-26 91.9 3.2 3.7e-26 91.0 3.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OAG14824.1 - 5.9e-26 91.3 0.0 8.3e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OAG14824.1 - 6.5e-15 55.2 16.4 1e-14 54.6 16.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG14824.1 - 5.9e-06 26.2 8.2 0.0015 18.4 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG14824.1 - 0.0026 17.7 8.0 0.24 11.5 0.9 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 OAG14824.1 - 0.044 14.2 8.2 1.3 9.5 1.3 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar TackOD1 PF18551.1 OAG14824.1 - 2.5 7.7 8.4 0.71 9.5 1.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Ribosomal_S17 PF00366.20 OAG14825.1 - 4.7e-17 61.9 3.2 4.7e-17 61.9 3.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 DUF4530 PF15039.6 OAG14825.1 - 0.0027 17.8 0.4 0.0044 17.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Cnd1_N PF12922.7 OAG14827.1 - 9.2e-60 201.3 0.0 3.6e-59 199.4 0.0 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 OAG14827.1 - 2.2e-47 161.1 10.0 3.1e-43 147.6 0.1 4.6 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG14827.1 - 4.2e-07 30.3 11.0 0.016 15.6 0.0 6.6 7 2 1 9 9 9 3 HEAT repeats HEAT PF02985.22 OAG14827.1 - 8.2e-07 28.8 10.8 0.23 11.8 0.1 7.9 7 1 1 8 8 8 2 HEAT repeat RTP1_C1 PF10363.9 OAG14827.1 - 3.2e-05 24.1 2.1 0.42 10.8 0.1 4.2 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 OAG14827.1 - 0.00014 21.2 3.6 0.0019 17.5 1.0 3.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OAG14827.1 - 0.018 15.5 9.4 34 5.1 0.2 6.0 5 0 0 5 5 5 0 HEAT-like repeat TIP120 PF08623.10 OAG14827.1 - 2 8.2 5.8 4.1 7.2 1.0 3.7 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Pkinase PF00069.25 OAG14828.1 - 2.4e-43 148.4 0.0 1.2e-39 136.3 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG14828.1 - 4.2e-13 49.2 0.0 9e-09 35.0 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG14828.1 - 0.00073 18.9 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAG14828.1 - 0.002 17.0 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG14828.1 - 0.0024 17.8 0.0 0.065 13.2 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG14828.1 - 0.038 13.6 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAG14828.1 - 0.047 13.0 0.1 0.15 11.4 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 OAG14829.1 - 1.3e-22 80.2 26.3 1.3e-22 80.2 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 OAG14829.1 - 0.0092 16.3 0.2 0.0092 16.3 0.2 3.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 OAG14830.1 - 5.5e-11 42.0 0.0 1.5e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14830.1 - 7.4e-05 22.8 14.2 0.00014 21.9 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 OAG14830.1 - 0.042 12.3 0.0 0.063 11.7 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B PhyH PF05721.13 OAG14831.1 - 1.6e-07 31.8 0.0 3.7e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG14831.1 - 1.4e-05 24.1 1.3 0.16 10.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 OAG14831.1 - 0.041 14.3 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAG14831.1 - 0.058 14.3 0.0 0.12 13.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_S15 PF02129.18 OAG14832.1 - 1.3e-38 133.1 0.7 7.3e-36 124.1 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG14832.1 - 4.5e-36 124.9 0.0 6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain LCAT PF02450.15 OAG14833.1 - 2.1e-106 356.4 0.0 2.5e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 OAG14833.1 - 0.046 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 OAG14833.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.25 OAG14834.1 - 9.4e-19 67.8 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG14834.1 - 5.2e-11 42.4 0.0 8.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG14834.1 - 1.7e-10 41.2 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG14834.1 - 3e-10 40.1 0.0 4.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG14834.1 - 1.4e-09 38.8 0.0 1.8e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG14834.1 - 9.9e-07 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG14834.1 - 7.2e-06 26.1 0.4 1.8e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG14834.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 OAG14834.1 - 0.0035 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase RNA_pol_Rpb2_6 PF00562.28 OAG14835.1 - 7.4e-110 367.7 0.1 9.9e-110 367.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG14835.1 - 6e-37 127.1 0.0 9.6e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAG14835.1 - 4.3e-27 94.1 0.0 1e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OAG14835.1 - 1.4e-25 89.1 0.0 2.9e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OAG14835.1 - 2.7e-22 79.3 0.0 4.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAG14835.1 - 2.1e-14 53.7 0.1 3.2e-13 49.9 0.1 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 BA14K PF07886.11 OAG14835.1 - 0.043 13.7 0.7 0.11 12.4 0.7 1.7 1 0 0 1 1 1 0 BA14K-like protein Rpr2 PF04032.16 OAG14835.1 - 0.069 13.4 0.7 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.21 OAG14836.1 - 1.9e-44 151.2 0.0 2.3e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OAG14836.1 - 3.8e-18 65.6 0.0 4.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG14836.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG14836.1 - 3.1e-08 33.3 0.0 3.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG14836.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG14836.1 - 9.3e-06 25.2 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG14836.1 - 0.00019 20.7 0.2 0.0011 18.2 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 OAG14836.1 - 0.0086 15.6 0.2 0.017 14.7 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG14836.1 - 0.054 13.6 0.0 0.31 11.1 0.1 1.9 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OAG14836.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RCR PF12273.8 OAG14837.1 - 3.7e-23 82.4 6.8 4.8e-23 82.1 6.8 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 OAG14837.1 - 5.2e-05 23.6 0.0 6.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 OAG14837.1 - 0.00018 21.3 0.4 0.00022 21.0 0.4 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TMEM119 PF15724.5 OAG14837.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 TMEM119 family LYRIC PF15686.5 OAG14837.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF2868 PF11067.8 OAG14837.1 - 0.041 13.4 0.2 0.045 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Comm PF15957.5 OAG14837.1 - 0.051 13.9 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Commissureless OSTbeta PF15048.6 OAG14837.1 - 0.083 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM51 PF15345.6 OAG14837.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2207 PF09972.9 OAG14837.1 - 0.17 10.6 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM52 PF14979.6 OAG14837.1 - 0.91 9.4 5.9 0.21 11.5 2.2 1.7 1 1 1 2 2 2 0 Transmembrane 52 WBP-1 PF11669.8 OAG14837.1 - 3.6 8.3 6.9 1.4 9.6 3.7 1.9 2 1 0 2 2 2 0 WW domain-binding protein 1 Coatomer_WDAD PF04053.14 OAG14838.1 - 8.7e-147 489.7 0.1 1.2e-146 489.3 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAG14838.1 - 5.5e-94 315.2 0.0 7.9e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAG14838.1 - 2.3e-33 113.7 19.1 1.3e-07 32.2 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14838.1 - 7e-06 26.3 1.4 0.081 13.2 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG14838.1 - 0.025 13.3 4.3 3.7 6.1 0.1 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 OAG14838.1 - 0.25 11.2 2.3 0.45 10.4 0.1 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS Nucleo_P87 PF07267.11 OAG14839.1 - 6.2 5.5 15.4 0.19 10.5 8.4 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Cupin_1 PF00190.22 OAG14840.1 - 1.6e-17 63.6 0.4 2.5e-17 62.9 0.4 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG14840.1 - 0.039 13.7 0.3 0.66 9.7 0.3 2.3 1 1 0 1 1 1 0 Cupin domain DegT_DnrJ_EryC1 PF01041.17 OAG14841.1 - 9.8e-98 327.8 0.0 1.4e-97 327.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 OAG14841.1 - 6e-21 75.5 0.0 1.6e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Aminotran_1_2 PF00155.21 OAG14841.1 - 2e-05 23.9 0.0 4.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG14841.1 - 0.02 13.5 0.0 0.08 11.5 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme GFO_IDH_MocA_C PF02894.17 OAG14841.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Beta_elim_lyase PF01212.21 OAG14841.1 - 0.052 12.8 0.0 0.45 9.7 0.0 2.1 1 1 1 2 2 2 0 Beta-eliminating lyase TrkA_N PF02254.18 OAG14841.1 - 0.066 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 OAG14841.1 - 0.084 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 OAG14841.1 - 0.099 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PCP PF02429.15 OAG14841.1 - 0.14 12.5 0.3 0.3 11.4 0.3 1.4 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein FMN_dh PF01070.18 OAG14842.1 - 1.4e-104 349.9 0.1 5.6e-104 347.9 0.1 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG14842.1 - 7.1e-07 28.7 0.1 2e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG14842.1 - 1.7e-06 27.3 0.9 0.00067 18.8 0.2 2.7 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 OAG14842.1 - 0.00012 21.6 0.3 0.97 8.8 0.0 3.0 3 0 0 3 3 3 2 Histidine biosynthesis protein NMO PF03060.15 OAG14842.1 - 0.00027 20.4 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAG14842.1 - 0.0012 18.2 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG14842.1 - 0.0015 17.7 0.5 0.0047 16.1 0.2 1.9 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OAG14842.1 - 0.031 13.5 0.3 1.2 8.2 0.0 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 OAG14842.1 - 0.046 13.1 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator GMC_oxred_N PF00732.19 OAG14843.1 - 2.2e-58 198.0 0.0 3e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG14843.1 - 4.1e-32 111.7 0.1 9.3e-32 110.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG14843.1 - 1.3e-06 27.8 0.0 1.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG14843.1 - 0.00011 21.6 0.0 0.00039 19.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG14843.1 - 0.0005 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG14843.1 - 0.0012 18.2 1.1 0.0019 17.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG14843.1 - 0.0013 18.3 0.3 0.0024 17.5 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG14843.1 - 0.0014 17.4 0.1 0.036 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG14843.1 - 0.009 15.1 0.0 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG14843.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG14843.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 OAG14843.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TPR_12 PF13424.6 OAG14845.1 - 8.8e-76 250.2 30.2 9.2e-15 54.7 0.2 7.2 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 OAG14845.1 - 1.1e-63 209.6 21.4 7.9e-10 38.3 0.0 10.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 OAG14845.1 - 1.9e-19 68.2 14.0 0.0029 17.5 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG14845.1 - 2.6e-16 59.9 11.4 6.3e-10 38.9 3.6 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 OAG14845.1 - 3e-13 49.0 15.1 0.15 12.0 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG14845.1 - 6.4e-13 47.7 17.1 0.11 12.6 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAG14845.1 - 3.5e-12 46.7 13.2 0.00065 20.3 0.8 6.6 7 2 1 8 8 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG14845.1 - 1.7e-11 44.4 12.8 0.0003 21.2 0.1 7.4 4 2 3 7 7 7 2 Tetratricopeptide repeat HET PF06985.11 OAG14845.1 - 5.4e-11 43.0 8.1 1e-08 35.7 1.0 3.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.6 OAG14845.1 - 1.7e-10 40.8 7.9 0.21 12.5 0.1 7.7 6 1 1 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAG14845.1 - 1.2e-09 37.7 0.0 4.2e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 OAG14845.1 - 4.4e-09 36.1 12.2 0.015 15.9 0.1 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG14845.1 - 9.3e-07 28.8 10.2 24 5.6 0.1 8.5 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG14845.1 - 5.3e-06 26.2 11.0 1.6 9.1 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG14845.1 - 2e-05 24.7 10.2 2.3 8.5 0.4 6.6 2 1 2 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 OAG14845.1 - 0.00092 19.1 9.0 6.6 6.8 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 OAG14845.1 - 0.002 18.2 0.0 5.7 7.4 0.0 4.5 4 0 0 4 4 3 1 PPR repeat AAA_16 PF13191.6 OAG14845.1 - 0.0025 18.2 0.1 0.032 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG14845.1 - 0.009 15.9 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.6 OAG14845.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain UDPG_MGDP_dh_N PF03721.14 OAG14846.1 - 9.6e-44 149.2 0.1 4.9e-43 146.9 0.1 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OAG14846.1 - 1.7e-30 105.0 0.0 4.3e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OAG14846.1 - 7.2e-20 71.4 0.0 3.9e-17 62.6 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 OAG14846.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_1b PF00579.25 OAG14847.1 - 1.1e-64 218.6 0.4 1.8e-64 217.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Sugarporin_N PF11471.8 OAG14847.1 - 0.0049 16.8 1.5 0.01 15.8 1.5 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Acyl-CoA_dh_2 PF08028.11 OAG14847.1 - 0.1 12.9 0.6 0.2 11.9 0.6 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4349 PF14257.6 OAG14847.1 - 0.1 12.0 0.3 0.18 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SNARE PF05739.19 OAG14847.1 - 0.15 12.1 0.5 0.32 11.0 0.5 1.5 1 0 0 1 1 1 0 SNARE domain Spc24 PF08286.11 OAG14847.1 - 0.24 11.6 1.1 0.56 10.5 1.1 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 OAG14847.1 - 0.35 11.1 5.9 0.2 12.0 2.8 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 OAG14847.1 - 1.1 9.5 9.5 6.7 7.0 3.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TFIID_20kDa PF03847.13 OAG14848.1 - 1.3e-22 80.0 0.2 2e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2390 PF09523.10 OAG14848.1 - 0.088 13.1 0.5 0.088 13.1 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2390) Exo_endo_phos PF03372.23 OAG14849.1 - 4.2e-13 49.3 0.0 6.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 OAG14849.1 - 0.0023 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Luciferase catalytic domain WD40 PF00400.32 OAG14850.1 - 3.8e-59 195.3 15.7 2.5e-11 43.9 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14850.1 - 4e-21 75.1 0.8 0.00079 19.7 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG14850.1 - 2.5e-08 33.2 0.2 0.058 12.3 0.0 4.4 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG14850.1 - 3.8e-08 33.4 0.0 0.00039 20.4 0.0 3.4 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG14850.1 - 5.7e-07 28.6 1.3 0.0059 15.3 0.4 4.6 2 2 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG14850.1 - 1.4e-06 27.9 0.0 0.00012 21.5 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 OAG14850.1 - 0.00039 18.9 0.0 0.0017 16.8 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 OAG14850.1 - 0.0039 16.3 0.3 3.2 6.8 0.0 3.6 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) PD40 PF07676.12 OAG14850.1 - 0.0046 16.8 3.5 4.2 7.4 0.0 4.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 OAG14850.1 - 0.0092 14.6 0.1 9.4 4.6 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain VID27 PF08553.10 OAG14850.1 - 0.017 14.2 0.1 1 8.4 0.0 3.1 2 1 2 4 4 4 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 OAG14850.1 - 0.16 10.6 1.1 3.8 6.1 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like PALB2_WD40 PF16756.5 OAG14850.1 - 0.21 10.5 0.9 7.9 5.3 0.2 3.2 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RrnaAD PF00398.20 OAG14851.1 - 1.1e-64 218.1 0.0 1.6e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAG14851.1 - 1.1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG14851.1 - 9.1e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG14851.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAG14851.1 - 0.0003 20.4 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OAG14851.1 - 0.00088 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG14851.1 - 0.0022 18.7 0.0 0.0058 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG14851.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG14851.1 - 0.036 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 OAG14851.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 OAG14851.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RHH_6 PF16762.5 OAG14851.1 - 0.12 13.0 0.1 0.27 11.9 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain AP_endonuc_2 PF01261.24 OAG14852.1 - 3.2e-32 111.7 0.1 4.8e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phage_T7_Capsid PF05396.11 OAG14852.1 - 0.055 13.8 0.4 0.15 12.4 0.4 1.7 1 0 0 1 1 1 0 Phage T7 capsid assembly protein HpaB_N PF11794.8 OAG14852.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Zn_clus PF00172.18 OAG14853.1 - 5.5e-09 36.0 9.1 1.3e-08 34.8 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.22 OAG14854.1 - 1.2e-17 63.9 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG14854.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain HET PF06985.11 OAG14857.1 - 2.6e-25 89.5 1.2 7e-25 88.1 1.2 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.21 OAG14858.1 - 2.2e-17 62.8 15.4 1.4e-16 60.1 15.4 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG14858.1 - 1.9e-09 36.9 12.6 2.5e-09 36.5 12.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2871 PF11070.8 OAG14858.1 - 0.024 14.9 0.3 0.064 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) DUF5592 PF17332.2 OAG14858.1 - 3.8 8.1 6.8 0.29 11.7 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5592) CorA PF01544.18 OAG14860.1 - 6.1e-06 25.8 2.5 2e-05 24.1 1.6 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein CorA PF01544.18 OAG14862.1 - 9.7e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RasGEF PF00617.19 OAG14863.1 - 1.9e-46 158.5 0.1 3e-46 157.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG14863.1 - 1e-11 45.0 0.5 2.1e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF3445 PF11927.8 OAG14865.1 - 2.9e-81 272.4 0.0 4.3e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 OAG14866.1 - 6.7e-78 262.8 21.2 8.2e-78 262.5 21.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family YitT_membrane PF02588.15 OAG14866.1 - 0.82 9.0 5.7 0.14 11.5 0.8 2.1 1 1 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Gar1 PF04410.14 OAG14867.1 - 1.5e-39 135.2 5.0 1.5e-39 135.2 5.0 2.4 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region SR-25 PF10500.9 OAG14867.1 - 2.8 7.5 42.2 2.9 7.4 3.5 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 OAG14868.1 - 9.1e-51 173.0 0.0 1.8e-50 172.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAG14868.1 - 1.9e-39 133.2 49.9 6.2e-10 38.7 5.9 9.8 5 3 4 10 10 10 8 Leucine rich repeat Guanylate_cyc PF00211.20 OAG14868.1 - 2.2e-31 108.9 0.0 1.7e-30 106.0 0.0 2.1 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 OAG14868.1 - 4.9e-31 106.2 60.8 0.00021 21.6 2.3 12.8 6 3 10 17 17 17 14 Leucine Rich repeats (2 copies) Ad_cyc_g-alpha PF08509.11 OAG14868.1 - 6.3e-06 25.8 0.4 2e-05 24.2 0.4 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 OAG14868.1 - 9.4e-06 26.2 0.1 8.3e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 OAG14868.1 - 1.6e-05 24.5 15.1 0.23 10.9 0.1 5.1 2 1 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OAG14868.1 - 0.00011 22.2 46.4 2.2 9.2 0.0 15.5 16 2 1 17 17 17 1 Leucine Rich Repeat LRR_5 PF13306.6 OAG14868.1 - 0.00062 19.7 0.0 1.7 8.6 0.0 3.4 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) ATP_bind_2 PF03668.15 OAG14869.1 - 0.0057 16.0 0.4 0.0079 15.5 0.4 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family CinA PF02464.17 OAG14870.1 - 8.6e-37 126.1 2.2 9.8e-37 125.9 2.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein FAM25 PF15825.5 OAG14870.1 - 0.16 12.3 1.9 0.25 11.7 0.4 1.9 2 0 0 2 2 2 0 FAM25 family p450 PF00067.22 OAG14871.1 - 3.8e-50 171.0 0.0 8.7e-50 169.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 InPase PF18823.1 OAG14871.1 - 0.06 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase DUF1654 PF07867.11 OAG14871.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Zn_clus PF00172.18 OAG14873.1 - 5.6e-09 36.0 13.1 9.9e-09 35.2 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP_bind_2 PF03668.15 OAG14875.1 - 0.0067 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family Ribophorin_I PF04597.14 OAG14876.1 - 7.2e-153 509.9 0.1 8.2e-153 509.7 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.12 OAG14877.1 - 6.2e-121 403.2 0.1 9.3e-121 402.7 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAG14877.1 - 1.9e-24 86.5 0.3 1.5e-12 47.5 0.0 2.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG14877.1 - 0.00022 20.7 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase RPE65 PF03055.15 OAG14878.1 - 1.5e-83 281.5 0.2 1.9e-83 281.2 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Msg2_C PF12373.8 OAG14878.1 - 0.16 11.4 0.5 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal IBR PF01485.21 OAG14879.1 - 1.8e-12 47.3 48.2 9.8e-10 38.5 4.8 4.5 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain Acetyltransf_1 PF00583.25 OAG14880.1 - 3.2e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG14880.1 - 6.2e-09 36.2 0.0 7.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG14880.1 - 1.5e-06 28.2 0.0 3.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG14880.1 - 9e-06 25.6 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG14880.1 - 0.0056 17.4 0.0 0.0091 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG14880.1 - 0.017 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 OAG14880.1 - 0.021 14.5 0.0 0.072 12.8 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 OAG14881.1 - 1.7e-10 40.7 0.0 3.3e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.21 OAG14881.1 - 0.0082 15.4 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DAO PF01266.24 OAG14881.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG14881.1 - 0.051 12.6 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG14881.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAG14881.1 - 0.12 12.6 0.1 0.86 9.9 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 OAG14881.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 OAG14882.1 - 2.8e-79 266.6 0.0 3.8e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG14882.1 - 1.1e-32 113.5 0.0 2.5e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG14882.1 - 0.00021 20.5 0.1 0.00031 19.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG14882.1 - 0.0041 16.3 0.1 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG14882.1 - 0.0047 16.2 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG14882.1 - 0.0091 15.6 1.0 0.05 13.2 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG14882.1 - 0.016 14.5 0.2 0.071 12.3 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAG14882.1 - 0.055 14.0 0.3 0.57 10.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AOX PF01786.17 OAG14883.1 - 2.1e-96 321.6 1.3 2.6e-96 321.3 1.3 1.1 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.18 OAG14884.1 - 1.4e-27 95.9 1.0 1.5e-27 95.8 1.0 1.0 1 0 0 1 1 1 1 Acylphosphatase CH PF00307.31 OAG14885.1 - 0.037 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain Cas_APE2256 PF09651.10 OAG14885.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Caskin1-CID PF16600.5 OAG14885.1 - 0.33 11.6 6.5 3.2 8.4 3.3 2.5 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain KAR9 PF08580.10 OAG14886.1 - 1.4e-128 430.4 43.6 1.4e-128 430.4 43.6 2.5 2 1 0 2 2 2 1 Yeast cortical protein KAR9 APG17 PF04108.12 OAG14886.1 - 0.19 10.8 3.4 0.12 11.4 1.1 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 HET PF06985.11 OAG14888.1 - 1.7e-26 93.3 0.3 3e-26 92.5 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CBM_5_12_2 PF14600.6 OAG14888.1 - 0.024 14.6 0.4 0.059 13.3 0.4 1.6 1 0 0 1 1 1 0 Cellulose-binding domain Fungal_trans PF04082.18 OAG14889.1 - 8.8e-15 54.5 0.2 1.8e-14 53.4 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14889.1 - 2e-07 31.0 8.9 4.2e-07 30.0 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_9 PF14604.6 OAG14891.1 - 1.5e-09 37.6 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG14891.1 - 5.8e-07 29.0 0.0 9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG14891.1 - 7.4e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 OAG14891.1 - 0.0026 17.9 4.6 0.0053 16.9 4.6 1.5 1 0 0 1 1 1 1 Podoplanin DTHCT PF08070.11 OAG14891.1 - 0.0096 16.6 0.5 0.034 14.9 0.5 1.9 1 0 0 1 1 1 1 DTHCT (NUC029) region LAT PF15234.6 OAG14892.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells Suf PF05843.14 OAG14893.1 - 0.07 13.1 1.3 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) adh_short_C2 PF13561.6 OAG14895.1 - 1.6e-36 126.1 0.2 2.1e-36 125.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG14895.1 - 1.8e-29 102.6 0.0 3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG14895.1 - 1.4e-05 25.1 0.1 2.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Ammonium_transp PF00909.21 OAG14896.1 - 3e-114 381.8 29.8 3.5e-114 381.6 29.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4379 PF14311.6 OAG14897.1 - 0.002 18.4 1.1 0.0077 16.6 1.1 2.0 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Clat_adaptor_s PF01217.20 OAG14898.1 - 5.2e-56 188.5 1.2 6e-56 188.3 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec23_trunk PF04811.15 OAG14899.1 - 1.8e-55 188.2 0.0 3.1e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG14899.1 - 8e-26 89.9 0.0 1.5e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAG14899.1 - 7.4e-18 65.1 0.0 1.8e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAG14899.1 - 2.4e-14 53.1 1.5 5.7e-14 51.9 1.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG14899.1 - 2.1e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L27A PF00828.19 OAG14900.1 - 1.2e-20 74.4 0.0 1.9e-20 73.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1593 PF07632.11 OAG14901.1 - 0.043 13.2 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) GatB_N PF02934.15 OAG14902.1 - 1e-95 320.2 0.0 1.4e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAG14902.1 - 3e-13 49.9 0.0 9.2e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 GatB domain DUF3391 PF11871.8 OAG14903.1 - 0.0074 16.8 2.9 0.0096 16.5 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) AAA_11 PF13086.6 OAG14904.1 - 0.84 9.4 8.0 1.2 8.8 8.0 1.2 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 OAG14904.1 - 0.89 8.2 7.8 1 7.9 7.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5542 PF17696.1 OAG14904.1 - 1.1 9.4 3.9 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Presenilin PF01080.17 OAG14904.1 - 3.1 6.5 8.7 3.9 6.2 8.7 1.1 1 0 0 1 1 1 0 Presenilin TMEM208_SND2 PF05620.11 OAG14904.1 - 3.5 7.4 9.2 1.1 9.1 1.5 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 MPP6 PF10175.9 OAG14904.1 - 5.4 7.5 18.2 7.3 7.1 18.2 1.2 1 0 0 1 1 1 0 M-phase phosphoprotein 6 LMBR1 PF04791.16 OAG14904.1 - 9.5 5.0 7.8 12 4.6 7.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.7 OAG14904.1 - 9.5 4.2 9.3 11 4.0 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Inositol_P PF00459.25 OAG14905.1 - 1.3e-60 205.2 0.0 1.5e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RRM_1 PF00076.22 OAG14907.1 - 8.2e-16 57.6 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.19 OAG14908.1 - 5e-128 426.5 0.0 6.3e-128 426.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG14908.1 - 3.9e-48 163.6 0.0 5.9e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG14908.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AD PF09793.9 OAG14909.1 - 1e-27 96.1 0.5 1.5e-27 95.6 0.5 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Pathogen_betaC1 PF09593.10 OAG14909.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein Helo_like_N PF17111.5 OAG14910.1 - 4.4e-09 36.0 4.7 7e-09 35.4 4.7 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAG14910.1 - 0.0028 17.9 2.8 0.0038 17.4 1.1 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ribosomal_L10 PF00466.20 OAG14910.1 - 0.11 12.7 0.2 17 5.7 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein L10 MarR_2 PF12802.7 OAG14910.1 - 0.14 12.1 0.1 12 5.9 0.0 2.6 3 0 0 3 3 3 0 MarR family NAM-associated PF14303.6 OAG14911.1 - 0.19 12.4 1.3 0.34 11.6 1.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CENP-F_leu_zip PF10473.9 OAG14912.1 - 0.012 15.7 1.9 0.03 14.4 1.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 OAG14912.1 - 0.044 12.4 1.8 0.078 11.6 1.8 1.3 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 OAG14912.1 - 0.63 10.3 4.7 0.72 10.1 1.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-ZPR1 PF03367.13 OAG14912.1 - 2.7 7.8 5.3 20 5.0 0.6 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Med3 PF11593.8 OAG14912.1 - 3.6 6.7 8.7 5.1 6.2 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Thioredoxin PF00085.20 OAG14913.1 - 3.6e-20 71.9 0.0 4.2e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG14913.1 - 1.2e-06 28.9 0.3 1.1e-05 25.9 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OAG14913.1 - 9.5e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG14913.1 - 0.0062 15.9 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 OAG14913.1 - 0.0067 16.4 0.0 0.0084 16.1 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 OAG14913.1 - 0.012 15.3 0.1 0.27 10.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 OAG14913.1 - 0.029 14.7 0.0 4.4 7.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Con-6 PF10346.9 OAG14914.1 - 1.2e-13 50.8 3.3 2e-13 50.1 3.3 1.4 1 0 0 1 1 1 1 Conidiation protein 6 Glyco_transf_24 PF18404.1 OAG14915.1 - 9.6e-148 490.8 1.0 1.5e-147 490.2 1.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAG14915.1 - 2.3e-67 227.6 0.0 2.2e-66 224.4 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAG14915.1 - 2.2e-52 178.1 0.0 5.3e-51 173.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OAG14915.1 - 4.1e-48 163.8 0.4 9.8e-48 162.6 0.4 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAG14915.1 - 1.4e-43 148.1 0.1 1.9e-42 144.4 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAG14915.1 - 1.9e-39 134.1 0.0 3.8e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 OAG14915.1 - 3.3e-05 23.6 0.2 6.5e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.16 OAG14916.1 - 4e-35 121.4 48.4 3.2e-33 115.1 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3431 PF11913.8 OAG14917.1 - 2.4e-85 285.7 0.2 3.1e-85 285.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Atg14 PF10186.9 OAG14917.1 - 0.24 10.4 0.3 0.32 10.0 0.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CFEM PF05730.11 OAG14920.1 - 3.2e-12 46.4 9.7 5.5e-12 45.6 9.7 1.4 1 0 0 1 1 1 1 CFEM domain HET PF06985.11 OAG14921.1 - 3.1e-14 53.5 7.6 3.6e-12 46.9 1.7 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Spherulin4 PF12138.8 OAG14922.1 - 5.8e-66 222.6 0.1 6.6e-66 222.4 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF851 PF05867.11 OAG14922.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF851) Beta_elim_lyase PF01212.21 OAG14924.1 - 3e-71 240.1 0.0 3.8e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAG14924.1 - 0.0032 16.1 0.0 0.0065 15.0 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG14924.1 - 0.0067 15.6 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG14924.1 - 0.056 12.7 0.1 0.12 11.6 0.1 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GATase PF00117.28 OAG14925.1 - 2.4e-10 40.5 0.0 3.1e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I MFS_1 PF07690.16 OAG14926.1 - 2.5e-51 174.7 29.8 2.1e-50 171.6 28.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG14926.1 - 1.3e-11 44.1 34.5 2.2e-10 40.0 34.6 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2975 PF11188.8 OAG14926.1 - 0.053 13.4 0.3 0.053 13.4 0.3 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2975) OATP PF03137.20 OAG14926.1 - 0.078 11.3 12.0 0.0064 14.8 5.7 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Vpu PF00558.19 OAG14926.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 Vpu protein DUF4381 PF14316.6 OAG14926.1 - 0.24 11.6 0.1 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FSH1 PF03959.13 OAG14927.1 - 4.5e-28 98.4 0.0 5.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG14927.1 - 0.025 14.4 0.1 2.8 7.7 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OAG14927.1 - 0.17 11.7 0.4 0.61 9.9 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Glutaredoxin PF00462.24 OAG14928.1 - 8.3e-19 67.6 0.0 6.7e-18 64.7 0.0 2.3 2 1 1 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 OAG14928.1 - 3.4e-13 49.5 0.0 7.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 OAG14928.1 - 0.0048 16.8 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 F plasmid transfer operon protein DUF3801 PF12687.7 OAG14928.1 - 0.018 15.1 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Thioredoxin_8 PF13905.6 OAG14928.1 - 0.045 14.1 0.0 1.3 9.4 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like TrbC_Ftype PF09673.10 OAG14928.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Brix PF04427.18 OAG14929.1 - 4.7e-39 134.5 0.5 6.1e-39 134.1 0.5 1.1 1 0 0 1 1 1 1 Brix domain MMS19_C PF12460.8 OAG14930.1 - 7.8e-106 354.7 3.3 4.4e-101 339.0 5.7 4.5 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 OAG14930.1 - 8.8e-100 333.6 0.0 1.3e-94 316.7 0.0 3.6 3 0 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 OAG14930.1 - 3.7e-06 27.2 4.0 0.012 16.0 0.4 5.6 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 OAG14930.1 - 0.004 17.6 9.8 0.18 12.4 0.3 6.0 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 OAG14930.1 - 0.027 14.7 5.0 13 6.4 0.1 5.6 6 0 0 6 6 6 0 HEAT repeat RTP1_C1 PF10363.9 OAG14930.1 - 0.067 13.4 0.4 2.3 8.4 0.0 3.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 THF_DHG_CYH PF00763.23 OAG14931.1 - 4.1e-23 81.9 0.0 6.6e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAG14931.1 - 3.1e-13 49.4 0.0 2.7e-09 36.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F-box PF00646.33 OAG14932.1 - 5.7e-07 29.3 0.8 1.2e-06 28.3 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG14932.1 - 0.0049 16.7 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like SH3_9 PF14604.6 OAG14933.1 - 1.7e-29 101.4 6.5 4.3e-15 55.3 0.6 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAG14933.1 - 1.5e-25 88.6 4.0 1e-12 47.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OAG14933.1 - 1.9e-14 53.1 0.0 4e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 OAG14933.1 - 2.6e-14 53.0 0.0 5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Spc7 PF08317.11 OAG14934.1 - 0.00076 18.5 5.3 0.00076 18.5 5.3 3.2 1 1 2 3 3 3 2 Spc7 kinetochore protein Mto2_bdg PF12808.7 OAG14934.1 - 0.034 14.4 1.8 0.98 9.8 0.2 3.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TolA_bind_tri PF16331.5 OAG14934.1 - 2.4 8.3 13.6 13 5.9 0.0 4.4 2 1 2 4 4 4 0 TolA binding protein trimerisation TBCA PF02970.16 OAG14934.1 - 5.2 7.5 18.6 2.3 8.6 1.1 3.8 3 1 0 3 3 3 0 Tubulin binding cofactor A V_ATPase_I PF01496.19 OAG14934.1 - 9.9 3.9 25.5 0.013 13.5 6.0 2.8 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PBP PF01161.20 OAG14935.1 - 2.8e-21 76.2 0.1 4.1e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Isochorismatase PF00857.20 OAG14936.1 - 2.9e-31 109.0 0.0 5.8e-31 108.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family LolA_like PF17131.4 OAG14936.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein Dynamin_M PF01031.20 OAG14937.1 - 3e-109 364.7 0.0 5.2e-109 363.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAG14937.1 - 1.4e-56 191.2 0.5 2.6e-56 190.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAG14937.1 - 7.7e-32 109.3 2.1 1.9e-31 108.1 2.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG14937.1 - 4.4e-05 23.5 0.3 0.00064 19.8 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG14937.1 - 0.13 11.8 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP-synt_E PF05680.12 OAG14938.1 - 1e-20 73.9 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain ATS PF15445.6 OAG14938.1 - 0.14 11.5 0.1 0.16 11.4 0.1 1.0 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 WD40 PF00400.32 OAG14939.1 - 6.2e-08 33.2 8.4 0.14 13.1 0.1 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat GFO_IDH_MocA_C PF02894.17 OAG14942.1 - 1.1e-17 64.1 0.4 4.2e-16 59.0 0.1 3.0 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 OAG14942.1 - 5.2e-17 62.8 0.2 1.1e-16 61.8 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG14942.1 - 0.12 13.1 0.3 0.32 11.7 0.3 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GPI-anchored PF10342.9 OAG14943.1 - 2.7e-15 56.9 0.9 2.7e-15 56.9 0.9 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RE_NgoFVII PF09565.10 OAG14944.1 - 0.032 13.5 0.6 0.038 13.3 0.6 1.0 1 0 0 1 1 1 0 NgoFVII restriction endonuclease DUF1942 PF09167.11 OAG14944.1 - 0.049 13.6 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) KIX_2 PF16987.5 OAG14944.1 - 0.096 12.7 0.9 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 KIX domain Peptidase_S30 PF01577.16 OAG14944.1 - 0.28 10.8 3.6 0.35 10.5 3.6 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease DTHCT PF08070.11 OAG14944.1 - 0.41 11.4 9.7 1.2 9.9 9.6 1.8 1 1 1 2 2 2 0 DTHCT (NUC029) region SET PF00856.28 OAG14945.1 - 9.3e-12 45.7 0.0 2.5e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAG14945.1 - 4.3e-07 29.9 14.8 4.3e-07 29.9 14.8 2.6 2 1 0 2 2 2 1 MYND finger LpxK PF02606.14 OAG14950.1 - 0.0072 15.5 0.0 0.0087 15.2 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Pex19 PF04614.12 OAG14950.1 - 0.064 13.0 1.7 0.12 12.1 1.7 1.4 1 0 0 1 1 1 0 Pex19 protein family SUR7 PF06687.12 OAG14951.1 - 1.1e-42 146.1 6.2 1.3e-42 145.8 6.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 OAG14951.1 - 1.4e-05 25.1 2.9 1.4e-05 25.1 2.9 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 TssO PF17561.2 OAG14951.1 - 0.085 13.0 0.0 0.085 13.0 0.0 2.8 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF1072 PF06380.11 OAG14951.1 - 0.75 9.7 4.9 2.8 7.9 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Amastin PF07344.11 OAG14951.1 - 3.9 7.3 12.7 1.3 8.9 6.8 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein EF-hand_1 PF00036.32 OAG14952.1 - 2.8e-26 89.1 4.8 2.7e-06 26.5 0.0 5.7 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 OAG14952.1 - 3e-24 82.8 3.7 1.8e-05 24.3 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OAG14952.1 - 1.5e-23 82.4 1.8 2.4e-11 43.3 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 OAG14952.1 - 1.1e-21 77.0 5.9 2.7e-09 37.3 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAG14952.1 - 1.1e-16 59.4 7.4 0.0014 18.0 0.1 4.9 5 1 0 5 5 5 4 EF hand SRF-TF PF00319.18 OAG14953.1 - 4e-24 83.9 0.2 6.1e-24 83.3 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Exonuc_VII_L PF02601.15 OAG14953.1 - 0.67 9.5 14.9 0.89 9.1 14.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.6 OAG14953.1 - 8.8 6.3 10.5 20 5.1 10.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF1708 PF08101.11 OAG14954.1 - 5.7e-174 579.3 0.7 7.4e-174 578.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) Vfa1 PF08432.10 OAG14955.1 - 4.9 7.4 6.8 4.5 7.6 4.5 2.1 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_61 PF03443.14 OAG14956.1 - 9.4e-54 182.5 0.1 1.2e-53 182.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4469 PF14734.6 OAG14956.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold DUF5624 PF18538.1 OAG14956.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Cyc-maltodext_C PF10438.9 OAG14957.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain DRMBL PF07522.14 OAG14958.1 - 1.8e-34 118.2 0.0 3.3e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OAG14958.1 - 6.7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Metallophos_2 PF12850.7 OAG14958.1 - 0.11 12.7 0.0 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain UBZ_FAAP20 PF15750.5 OAG14958.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DIOX_N PF14226.6 OAG14959.1 - 6.3e-17 62.4 0.0 1.2e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG14959.1 - 1.9e-15 57.1 0.0 4.7e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 OAG14960.1 - 8.1e-07 29.1 7.6 1.7e-06 28.0 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 OAG14961.1 - 1.2e-63 215.5 0.3 1.5e-63 215.2 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG14961.1 - 3.7e-20 72.9 0.4 8.9e-16 58.4 0.3 2.8 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAG14961.1 - 0.0036 16.7 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 OAG14962.1 - 2.4e-47 161.5 32.2 1e-46 159.5 32.2 1.7 1 1 0 1 1 1 1 Permease family Cys_rich_VLP PF14194.6 OAG14962.1 - 0.27 11.4 1.1 1.6 8.9 0.7 2.1 2 0 0 2 2 2 0 Cysteine-rich VLP Fungal_trans PF04082.18 OAG14963.1 - 2.7e-07 29.9 0.4 5.7e-07 28.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG14963.1 - 7.6e-07 29.2 6.9 1.5e-06 28.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WRC PF08879.10 OAG14964.1 - 0.063 13.0 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 WRC FeS_assembly_P PF01883.19 OAG14965.1 - 1.5e-08 34.7 0.0 4.3e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein NAP PF00956.18 OAG14966.1 - 0.054 12.7 3.0 0.066 12.4 3.0 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) vATP-synt_E PF01991.18 OAG14966.1 - 0.18 11.2 3.4 0.25 10.7 3.4 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit LSM PF01423.22 OAG14968.1 - 6.6e-16 57.8 0.0 9.8e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG14968.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 OAG14968.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Methyltransf_11 PF08241.12 OAG14969.1 - 5.8e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG14969.1 - 0.0085 16.8 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG14969.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribul_P_3_epim PF00834.19 OAG14970.1 - 2.5e-62 209.8 0.0 2.3e-61 206.6 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 OAG14970.1 - 0.013 15.0 0.0 0.35 10.3 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein QRPTase_C PF01729.19 OAG14970.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 OAG14970.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-RING_2 PF13639.6 OAG14972.1 - 2.1e-10 40.8 6.2 3.3e-10 40.1 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG14972.1 - 5.4e-07 29.5 6.1 1.2e-06 28.5 6.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG14972.1 - 2.2e-06 27.5 6.0 3.5e-06 26.9 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG14972.1 - 2.7e-05 23.8 4.4 2.7e-05 23.8 4.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 OAG14972.1 - 3.1e-05 23.7 5.7 5.6e-05 22.9 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG14972.1 - 4.1e-05 23.8 3.7 9e-05 22.7 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG14972.1 - 4.8e-05 23.1 5.8 8e-05 22.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG14972.1 - 0.00018 21.3 4.4 0.00028 20.7 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG14972.1 - 0.00056 19.7 5.4 0.00098 18.9 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG14972.1 - 0.0037 17.3 1.4 0.0069 16.4 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OAG14972.1 - 0.015 15.4 6.1 0.026 14.7 6.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING VATC PF18716.1 OAG14972.1 - 0.049 13.5 2.1 0.37 10.7 0.4 2.3 2 0 0 2 2 2 0 Vms1-associating treble clef domain RNase_T PF00929.24 OAG14973.1 - 2.4e-07 31.4 0.0 7.5e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Filament PF00038.21 OAG14974.1 - 0.095 12.3 4.2 0.21 11.1 3.8 1.8 1 1 0 1 1 1 0 Intermediate filament protein XkdW PF09636.10 OAG14974.1 - 0.23 11.6 0.7 3.2 7.9 0.1 2.8 2 1 0 2 2 2 0 XkdW protein GAS PF13851.6 OAG14974.1 - 1.9 7.8 5.7 12 5.2 1.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 OAG14974.1 - 2.2 8.9 11.5 9.7 6.9 0.4 3.3 2 1 1 3 3 3 0 SlyX Ribonuclease_T2 PF00445.18 OAG14975.1 - 3.4e-37 128.5 0.1 4.4e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Lactamase_B_2 PF12706.7 OAG14977.1 - 1.9e-35 122.2 0.0 1.1e-34 119.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG14977.1 - 3.2e-11 43.4 0.0 5.6e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG14977.1 - 0.83 9.6 4.9 1.2 9.1 1.7 2.4 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily AAA PF00004.29 OAG14978.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG14978.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG14978.1 - 0.00012 22.0 0.1 0.00062 19.8 0.0 2.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG14978.1 - 0.00014 22.2 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OAG14978.1 - 0.00034 20.8 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG14978.1 - 0.00059 20.2 0.1 0.011 16.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAG14978.1 - 0.0013 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG14978.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG14978.1 - 0.026 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG14978.1 - 0.029 13.9 0.0 0.095 12.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG14978.1 - 0.044 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OAG14978.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG14978.1 - 0.052 13.3 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OAG14978.1 - 0.083 12.7 0.6 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OAG14978.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAG14978.1 - 0.097 12.4 0.2 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAG14978.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG14978.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG14978.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 OAG14979.1 - 5.9e-146 486.9 15.8 6.6e-146 486.8 15.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ELMO_CED12 PF04727.13 OAG14981.1 - 1.6e-48 165.1 0.2 3.4e-48 164.1 0.2 1.5 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 OAG14981.1 - 2.7e-38 131.5 0.0 5.1e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 OAG14981.1 - 5.3e-14 52.4 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Spidroin_MaSp PF11260.8 OAG14981.1 - 0.22 11.8 5.2 0.11 12.8 1.7 2.3 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 DUF3552 PF12072.8 OAG14981.1 - 0.36 10.2 1.9 0.57 9.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Siva PF05458.12 OAG14982.1 - 0.00069 19.4 11.5 0.00095 18.9 11.5 1.2 1 0 0 1 1 1 1 Cd27 binding protein (Siva) A_deaminase PF00962.22 OAG14983.1 - 6.1e-123 410.3 0.1 8.8e-123 409.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase RRM_1 PF00076.22 OAG14984.1 - 3.3e-38 129.3 0.5 1.8e-22 78.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG14984.1 - 0.0019 17.8 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG14984.1 - 0.015 15.1 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG14984.1 - 0.18 11.8 3.1 0.41 10.7 0.0 2.9 3 1 0 3 3 3 0 RNA binding motif TPR_1 PF00515.28 OAG14985.1 - 2.6e-21 74.5 2.0 1.4e-07 31.0 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG14985.1 - 3.1e-20 70.6 4.5 3.8e-06 26.6 0.1 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAG14985.1 - 1.1e-15 57.9 5.4 1.7e-06 28.5 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG14985.1 - 2.2e-15 56.0 5.5 2.1e-05 25.0 0.1 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG14985.1 - 2.5e-15 55.9 3.5 1.1e-07 31.4 0.0 5.1 4 2 1 5 5 5 3 TPR repeat TPR_19 PF14559.6 OAG14985.1 - 2.1e-13 50.6 2.5 0.0015 19.0 0.1 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG14985.1 - 1.1e-10 41.2 1.7 0.21 12.0 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG14985.1 - 3.7e-10 39.2 0.7 0.0015 18.6 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG14985.1 - 1.2e-09 37.5 1.9 0.089 12.9 0.0 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG14985.1 - 6.3e-09 35.8 1.1 0.0016 18.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG14985.1 - 6.2e-08 32.8 4.5 0.00027 21.2 0.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 OAG14985.1 - 9.4e-08 32.3 6.2 0.002 18.4 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG14985.1 - 5.1e-06 26.8 2.0 15 6.5 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG14985.1 - 1.7e-05 25.0 1.9 0.003 17.7 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAG14985.1 - 0.002 17.4 1.5 0.77 8.9 0.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 OAG14985.1 - 0.012 15.7 0.1 38 4.4 0.0 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 OAG14985.1 - 0.013 15.5 0.0 0.99 9.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG14985.1 - 0.015 15.2 1.9 4.1 7.4 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 OAG14985.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4919 PF16266.5 OAG14985.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) PMT PF02366.18 OAG14986.1 - 7.6e-84 281.1 16.4 7.6e-84 281.1 16.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UAA PF08449.11 OAG14986.1 - 4.5e-82 275.6 9.3 4.5e-82 275.6 9.3 1.8 3 0 0 3 3 3 1 UAA transporter family PMT_4TMC PF16192.5 OAG14986.1 - 2.8e-71 239.2 3.0 2.8e-71 239.2 3.0 3.8 4 1 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG14986.1 - 7.9e-07 29.1 1.0 8e-05 22.6 1.0 2.5 1 1 0 1 1 1 1 MIR domain Nuc_sug_transp PF04142.15 OAG14986.1 - 0.00016 20.9 7.3 0.00063 19.0 7.3 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF334 PF03904.13 OAG14986.1 - 0.13 11.8 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) TssN PF17555.2 OAG14986.1 - 2.3 7.5 6.8 0.35 10.2 1.6 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 OAG14987.1 - 1.2e-12 48.1 4.0 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG14987.1 - 0.013 15.8 0.1 3.5 8.0 0.0 3.7 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L3 PF00297.22 OAG14988.1 - 5e-183 608.2 8.7 5.6e-183 608.0 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 FAD_binding_2 PF00890.24 OAG14989.1 - 1.9e-126 422.6 4.2 2.3e-126 422.2 4.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAG14989.1 - 2.6e-45 153.5 0.4 3.9e-45 153.0 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 OAG14989.1 - 1.4e-05 24.3 1.9 0.012 14.7 1.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAG14989.1 - 3.5e-05 23.2 0.1 0.032 13.5 0.1 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 OAG14989.1 - 4.9e-05 22.7 0.3 0.0019 17.5 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG14989.1 - 0.003 16.9 0.1 0.0058 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG14989.1 - 0.046 13.3 2.2 0.27 10.7 2.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG14989.1 - 0.071 11.8 0.3 0.25 10.0 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Epimerase PF01370.21 OAG14990.1 - 6.5e-08 32.3 0.2 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG14990.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Abhydrolase_1 PF00561.20 OAG14991.1 - 2e-15 57.1 0.1 1.9e-13 50.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG14991.1 - 1.9e-11 43.7 0.0 1.7e-07 30.8 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG14991.1 - 2.1e-08 35.1 0.0 2.9e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAG14991.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 OAG14991.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 OAG14991.1 - 0.14 11.6 0.1 11 5.5 0.1 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 OAG14991.1 - 0.15 11.6 0.0 8.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 OAG14991.1 - 0.22 10.2 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 OAG14992.1 - 2e-14 53.9 0.1 1.3e-13 51.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG14992.1 - 4.5e-10 40.5 1.8 7.5e-10 39.8 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG14992.1 - 0.0041 16.4 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG14992.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 OAG14992.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Misat_Tub_SegII PF10644.9 OAG14993.1 - 0.15 12.3 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain NmrA PF05368.13 OAG14994.1 - 1.4e-13 51.0 0.0 3.3e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG14994.1 - 1.5e-10 41.2 0.0 4.2e-09 36.5 0.0 2.7 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG14994.1 - 0.0021 17.6 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG14994.1 - 0.097 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAGK PF15284.6 OAG14995.1 - 0.14 12.1 0.3 0.4 10.6 0.3 1.8 1 0 0 1 1 1 0 Phage-encoded virulence factor Peptidase_S8 PF00082.22 OAG14997.1 - 1.7e-35 122.7 14.4 3.2e-35 121.9 14.4 1.4 1 0 0 1 1 1 1 Subtilase family Sortilin-Vps10 PF15902.5 OAG14999.1 - 1.9e-291 966.3 23.2 1.8e-153 511.5 8.3 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAG14999.1 - 5.8e-84 280.6 21.0 3.5e-43 147.9 4.0 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 OAG14999.1 - 7.9e-07 28.2 38.9 0.79 10.0 0.0 11.1 11 0 0 11 11 11 5 BNR/Asp-box repeat PSII_BNR PF14870.6 OAG14999.1 - 2.7e-06 26.9 11.4 1e-05 25.0 0.0 5.1 5 2 0 5 5 5 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 OAG14999.1 - 0.0044 17.0 7.3 0.38 11.0 0.1 5.3 5 0 0 5 5 5 1 BNR-Asp box repeat NAD_binding_8 PF13450.6 OAG15000.1 - 8.7e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG15000.1 - 5.2e-05 22.8 0.0 9.5e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG15000.1 - 0.0002 21.1 0.0 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG15000.1 - 0.0018 17.4 0.0 0.0093 15.1 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG15000.1 - 0.0018 17.5 0.0 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG15000.1 - 0.0025 17.0 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG15000.1 - 0.0041 15.9 0.0 0.0066 15.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG15000.1 - 0.0077 16.2 0.2 0.043 13.8 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG15000.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG15000.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3176 PF11374.8 OAG15001.1 - 7.4e-35 119.4 3.0 8.7e-35 119.2 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MFS_1 PF07690.16 OAG15002.1 - 4.7e-29 101.4 23.6 2e-16 59.9 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15002.1 - 1.9e-07 30.3 17.9 0.00029 19.8 0.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG15002.1 - 1.2e-06 27.1 4.0 0.033 12.5 0.1 3.1 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAG15002.1 - 1.9e-05 23.4 20.2 0.0009 17.9 10.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 OAG15002.1 - 2.2e-05 23.1 9.0 0.01 14.3 1.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector UCR_Fe-S_N PF10399.9 OAG15002.1 - 0.0063 15.8 3.8 1.2 8.5 0.4 2.8 2 0 0 2 2 2 2 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1_like PF12832.7 OAG15002.1 - 0.01 14.8 6.1 0.12 11.2 2.7 2.3 1 1 0 2 2 2 1 MFS_1 like family DUF515 PF04415.12 OAG15003.1 - 0.014 13.8 1.1 0.019 13.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RRN3 PF05327.11 OAG15003.1 - 0.2 10.1 1.8 0.28 9.7 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SelP_N PF04592.14 OAG15003.1 - 6.7 6.0 13.5 10 5.5 13.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PCI PF01399.27 OAG15004.1 - 3.7e-08 33.8 0.1 7.6e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 PCI domain CSN7a_helixI PF18392.1 OAG15004.1 - 0.00046 20.0 0.1 0.00089 19.1 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain DUF5543 PF17697.1 OAG15004.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5543) HMA PF00403.26 OAG15005.1 - 7.6e-49 164.0 1.7 6.4e-13 48.9 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 OAG15005.1 - 4e-48 163.3 0.6 4e-48 163.3 0.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG15005.1 - 4.2e-31 108.9 2.3 9.9e-31 107.7 0.5 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG15005.1 - 0.0013 18.5 0.5 0.0039 17.0 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Antigen_Bd37 PF11641.8 OAG15005.1 - 0.046 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zinc_ribbon_12 PF11331.8 OAG15005.1 - 0.11 12.4 2.1 40 4.1 0.0 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain DSBA PF01323.20 OAG15005.1 - 0.13 12.0 1.0 8.5 6.1 0.0 3.6 4 0 0 4 4 4 0 DSBA-like thioredoxin domain FAM70 PF14967.6 OAG15005.1 - 0.15 11.5 0.5 3.6 7.0 0.0 2.7 2 1 0 3 3 3 0 FAM70 protein DUF678 PF05077.12 OAG15005.1 - 0.26 11.5 4.1 5.6 7.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Ras PF00071.22 OAG15006.1 - 5.1e-41 140.0 0.0 6.6e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG15006.1 - 1.3e-28 99.6 0.0 1.7e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG15006.1 - 1.2e-10 41.1 0.0 5.5e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG15006.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG15006.1 - 0.0048 16.5 0.0 0.043 13.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAG15006.1 - 0.0049 17.3 0.1 0.014 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 OAG15006.1 - 0.0081 16.7 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 OAG15006.1 - 0.0088 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAG15006.1 - 0.011 15.4 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAG15006.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OAG15006.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG15006.1 - 0.045 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG15006.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.10 OAG15006.1 - 0.12 11.7 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PAF-AH_p_II PF03403.13 OAG15007.1 - 2.1e-47 161.5 0.0 3.6e-47 160.7 0.0 1.3 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG15007.1 - 1.5e-06 27.3 0.0 4.4e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG15007.1 - 0.00042 19.4 0.0 0.00071 18.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 OAG15007.1 - 0.00076 18.8 0.8 0.0034 16.7 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG15007.1 - 0.13 12.4 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Thioesterase domain DLH PF01738.18 OAG15007.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family SAD_SRA PF02182.17 OAG15008.1 - 8.9e-33 113.2 0.5 1.9e-32 112.1 0.5 1.6 1 0 0 1 1 1 1 SAD/SRA domain Sedlin_N PF04628.13 OAG15008.1 - 0.065 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF2718 PF10918.8 OAG15008.1 - 1.5 9.3 5.5 3.8 8.0 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2718) Allexi_40kDa PF05549.11 OAG15008.1 - 5.3 6.5 12.0 0.41 10.1 0.1 2.9 1 1 2 3 3 3 0 Allexivirus 40kDa protein DivIVA PF05103.13 OAG15008.1 - 7.8 6.6 12.6 3.6 7.7 8.0 2.3 2 0 0 2 2 2 0 DivIVA protein Noc2 PF03715.13 OAG15009.1 - 2.3e-128 427.6 0.1 3.8e-128 426.9 0.1 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 OAG15009.1 - 0.0032 15.8 1.8 0.0032 15.8 1.8 4.1 2 2 1 3 3 3 1 Nop14-like family VPS28 PF03997.12 OAG15010.1 - 1.6e-70 236.6 0.2 1.9e-70 236.4 0.2 1.1 1 0 0 1 1 1 1 VPS28 protein C-C_Bond_Lyase PF15617.6 OAG15010.1 - 0.018 14.2 0.3 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold NDC10_II PF16787.5 OAG15010.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MSA-2c PF12238.8 OAG15010.1 - 0.093 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Methyltransf_16 PF10294.9 OAG15011.1 - 7.8e-21 74.6 0.0 3.7e-20 72.4 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG15011.1 - 4.5e-08 33.1 0.0 7.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15011.1 - 0.099 13.4 0.2 0.31 11.8 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain ADH_N PF08240.12 OAG15012.1 - 2.2e-32 111.2 1.0 3e-32 110.8 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15012.1 - 9.2e-24 83.9 0.5 1.8e-23 82.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG15012.1 - 2.6e-10 40.1 0.1 4.7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG15012.1 - 7.9e-05 23.7 0.0 0.00016 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG15012.1 - 9.3e-05 21.8 0.5 0.00015 21.2 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OAG15012.1 - 0.002 17.7 0.4 0.0039 16.8 0.4 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAG15012.1 - 0.0025 17.1 0.1 0.0051 16.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.6 OAG15012.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15012.1 - 0.061 14.0 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 OAG15012.1 - 0.088 12.9 2.5 0.24 11.5 1.1 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MTS PF05175.14 OAG15012.1 - 0.091 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HI0933_like PF03486.14 OAG15012.1 - 0.11 11.2 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_8 PF08022.12 OAG15014.1 - 8.3e-24 83.8 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG15014.1 - 7.8e-22 78.1 0.0 1.2e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG15014.1 - 6.9e-19 68.2 10.7 6.9e-19 68.2 10.7 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component ADH_N PF08240.12 OAG15015.1 - 7.4e-27 93.4 2.1 8.6e-27 93.2 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15015.1 - 1.8e-17 63.5 0.0 2.7e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG15015.1 - 2.8e-05 23.7 0.1 0.0022 17.5 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 OAG15015.1 - 0.093 12.3 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EthD PF07110.11 OAG15016.1 - 4.7e-05 24.5 0.0 5.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain GMC_oxred_N PF00732.19 OAG15017.1 - 3.6e-63 213.7 0.0 4.8e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG15017.1 - 7.5e-27 94.6 0.0 4.1e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 OAG15017.1 - 1e-05 25.3 0.2 0.00029 20.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG15017.1 - 8.5e-05 21.9 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG15017.1 - 0.00022 21.4 0.0 0.00075 19.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG15017.1 - 0.00047 19.3 0.0 0.0007 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG15017.1 - 0.00062 19.0 0.1 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG15017.1 - 0.00069 18.9 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG15017.1 - 0.001 18.4 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG15017.1 - 0.066 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding adh_short_C2 PF13561.6 OAG15018.1 - 9.6e-33 113.7 0.1 4.7e-19 68.9 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15018.1 - 3.5e-28 98.4 0.4 9.5e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG15018.1 - 0.00037 20.5 0.2 0.0008 19.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Zn_clus PF00172.18 OAG15019.1 - 2.6e-07 30.6 7.0 4.9e-07 29.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 OAG15020.1 - 2.4e-34 118.9 0.0 5.4e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAG15020.1 - 1.8e-15 56.5 0.0 4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 OAG15021.1 - 2.8e-06 27.4 0.2 4.2e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SNF2_N PF00176.23 OAG15024.1 - 4.9e-66 222.8 1.2 8.2e-66 222.1 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG15024.1 - 8.8e-15 55.0 0.0 1.7e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG15024.1 - 5.7e-10 39.5 0.2 1.8e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 OAG15024.1 - 6.9e-09 35.4 3.6 1.5e-08 34.4 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG15024.1 - 1.8e-07 31.0 4.4 4.5e-07 29.8 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG15024.1 - 8.1e-07 28.8 5.9 2.1e-06 27.5 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG15024.1 - 1.9e-06 27.6 1.5 1.9e-06 27.6 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG15024.1 - 2.9e-06 27.5 6.1 8.4e-06 26.0 6.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG15024.1 - 2.5e-05 24.1 2.7 7.9e-05 22.5 2.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG15024.1 - 0.00086 19.1 7.3 0.006 16.4 7.4 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG15024.1 - 0.0022 18.1 6.3 0.0069 16.5 6.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Sec20 PF03908.13 OAG15024.1 - 0.021 14.8 0.4 0.021 14.8 0.4 1.8 2 0 0 2 2 1 0 Sec20 HDA2-3 PF11496.8 OAG15024.1 - 0.053 12.7 0.2 0.12 11.5 0.2 1.7 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SPT6_acidic PF14632.6 OAG15024.1 - 0.078 13.6 15.3 0.47 11.1 15.3 2.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 Baculo_IE-1 PF05290.11 OAG15024.1 - 0.092 12.7 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 OAG15024.1 - 0.15 11.9 4.0 0.81 9.5 4.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pox_RNA_Pol_19 PF05320.12 OAG15024.1 - 0.3 11.1 6.2 0.065 13.2 2.3 2.0 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.14 OAG15024.1 - 1.1 7.5 10.7 2.1 6.6 10.7 1.3 1 0 0 1 1 1 0 CDC45-like protein HAMP PF00672.25 OAG15025.1 - 6.5e-34 116.1 22.7 1.4e-06 28.6 0.1 7.8 6 2 1 7 7 7 5 HAMP domain HATPase_c PF02518.26 OAG15025.1 - 5.3e-30 104.2 0.1 2.6e-29 102.0 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG15025.1 - 2.8e-28 98.3 0.3 2.4e-27 95.3 0.1 2.6 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG15025.1 - 2.3e-16 59.6 0.5 2.3e-16 59.6 0.5 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 OAG15025.1 - 9.8e-10 38.7 9.8 1.2 9.5 0.1 7.3 4 2 3 7 7 7 3 Syntaxin-like protein DUF4279 PF14106.6 OAG15025.1 - 1.4e-05 25.2 0.6 4.6 7.5 0.0 5.8 6 0 0 6 6 6 1 Domain of unknown function (DUF4279) DUF948 PF06103.11 OAG15025.1 - 0.0011 19.2 49.6 0.015 15.6 1.0 10.0 4 2 3 7 7 7 2 Bacterial protein of unknown function (DUF948) DUF3829 PF12889.7 OAG15025.1 - 0.0045 16.5 7.3 0.69 9.3 0.0 4.5 3 2 1 4 4 4 1 Protein of unknown function (DUF3829) HSBP1 PF06825.12 OAG15025.1 - 0.018 14.9 0.3 1 9.3 0.4 4.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Cbl_N PF02262.16 OAG15025.1 - 0.057 13.4 0.0 12 6.0 0.0 3.3 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 AdHead_fibreRBD PF16812.5 OAG15025.1 - 0.085 12.7 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre REF PF05755.12 OAG15025.1 - 0.087 12.6 11.5 3.4 7.4 0.3 5.3 2 2 4 6 6 6 0 Rubber elongation factor protein (REF) Ribosomal_S20p PF01649.18 OAG15025.1 - 0.32 11.7 1.7 5.9 7.6 0.8 3.0 2 0 0 2 2 2 0 Ribosomal protein S20 SpoIIID PF12116.8 OAG15025.1 - 0.5 10.5 2.2 16 5.7 0.0 4.0 4 0 0 4 4 2 0 Stage III sporulation protein D Fib_alpha PF08702.10 OAG15025.1 - 1.5 9.0 29.8 0.45 10.7 0.2 7.1 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF4763 PF15960.5 OAG15025.1 - 3.3 7.0 7.6 20 4.4 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4763) DUF883 PF05957.13 OAG15025.1 - 5.1 7.8 17.2 8.6 7.0 0.5 6.2 3 1 4 8 8 8 0 Bacterial protein of unknown function (DUF883) CMD PF02627.20 OAG15025.1 - 5.9 7.0 6.6 52 4.0 0.0 4.8 6 0 0 6 6 6 0 Carboxymuconolactone decarboxylase family DUF4795 PF16043.5 OAG15025.1 - 7.6 6.1 22.6 14 5.2 3.1 5.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) AcylCoA_dehyd_C PF12186.8 OAG15025.1 - 9.5 6.4 15.2 43 4.3 0.2 6.5 6 0 0 6 6 6 0 Acyl-CoA dehydrogenase C terminal zf-RING_2 PF13639.6 OAG15026.1 - 6.8e-13 48.7 7.0 1e-12 48.1 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG15026.1 - 1.2e-09 37.9 6.6 1.8e-09 37.3 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG15026.1 - 7.7e-09 35.7 8.6 1.5e-08 34.8 8.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG15026.1 - 1.4e-08 34.6 5.3 2.9e-08 33.6 2.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG15026.1 - 4.7e-08 32.9 5.4 7.4e-08 32.2 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG15026.1 - 1.1e-07 31.5 7.0 1.8e-07 30.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG15026.1 - 5.5e-07 29.2 4.1 9.2e-07 28.5 4.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OAG15026.1 - 1.6e-05 24.8 4.5 3.3e-05 23.8 4.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAG15026.1 - 4.4e-05 23.3 3.4 7.4e-05 22.5 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG15026.1 - 9.9e-05 21.9 5.3 0.00018 21.1 5.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAG15026.1 - 0.00055 20.1 5.6 0.004 17.3 5.6 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 OAG15026.1 - 0.00062 19.6 6.6 0.00085 19.1 5.4 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAG15026.1 - 0.0021 17.8 3.4 0.0032 17.2 3.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG15026.1 - 0.01 16.0 5.0 0.019 15.1 5.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OAG15026.1 - 0.012 15.7 6.1 0.02 15.0 6.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 OAG15026.1 - 0.071 13.0 0.9 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.11 OAG15026.1 - 0.11 12.8 6.2 0.74 10.2 6.2 2.1 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 OAG15026.1 - 0.13 12.1 5.6 0.22 11.5 5.6 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 OAG15026.1 - 0.15 12.2 2.2 0.25 11.5 2.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 OAG15026.1 - 0.17 11.8 6.8 0.095 12.6 1.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 OAG15026.1 - 0.27 11.3 3.2 1 9.5 3.2 1.9 1 1 0 1 1 1 0 Zinc-finger zf-UDP PF14569.6 OAG15026.1 - 0.36 11.0 2.3 0.61 10.2 2.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2HC5 PF06221.13 OAG15026.1 - 0.74 9.9 6.2 0.78 9.8 0.4 2.2 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF5102 PF17104.5 OAG15027.1 - 5.9e-103 344.9 2.9 5.9e-103 344.9 2.9 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 OAG15028.1 - 9.6e-40 135.0 3.7 9.6e-40 135.0 3.7 2.4 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 OAG15028.1 - 0.00013 22.7 82.7 0.00049 20.9 42.0 6.9 1 1 4 5 5 4 3 Nucleoporin FG repeat region BRE1 PF08647.11 OAG15028.1 - 0.0068 16.4 16.3 0.11 12.6 3.4 2.3 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase hDGE_amylase PF14701.6 OAG15028.1 - 0.01 15.0 5.9 0.017 14.2 5.9 1.3 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain OmpH PF03938.14 OAG15028.1 - 0.021 15.2 18.1 0.061 13.6 4.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_S64 PF08192.11 OAG15028.1 - 0.052 12.0 7.8 0.083 11.4 7.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 ERM PF00769.19 OAG15028.1 - 0.12 12.2 17.4 0.28 11.0 17.4 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 OAG15028.1 - 0.12 11.6 17.6 0.043 13.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 OAG15028.1 - 0.15 12.3 20.9 0.045 14.0 6.7 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 OAG15028.1 - 0.17 10.5 12.3 0.059 12.0 5.9 1.9 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.12 OAG15028.1 - 0.31 11.1 12.8 2.5 8.1 3.1 3.0 1 1 2 3 3 3 0 Laminin Domain II Taxilin PF09728.9 OAG15028.1 - 0.53 9.4 14.4 0.12 11.5 1.6 2.3 2 0 0 2 2 2 0 Myosin-like coiled-coil protein GldM_N PF12081.8 OAG15028.1 - 0.54 10.3 6.9 0.99 9.5 6.9 1.3 1 0 0 1 1 1 0 GldM N-terminal domain BLOC1_2 PF10046.9 OAG15028.1 - 0.61 10.4 11.9 2.5 8.5 3.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OAG15028.1 - 1 9.4 9.8 3.2 7.8 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 OAG15028.1 - 1.4 9.3 19.7 2 8.8 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WXG100 PF06013.12 OAG15028.1 - 2 8.7 14.7 0.84 9.9 0.8 3.9 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Atg14 PF10186.9 OAG15028.1 - 2.2 7.3 6.7 3.5 6.6 6.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 OAG15028.1 - 2.4 8.6 10.6 4 7.9 10.6 1.3 1 0 0 1 1 1 0 AAA domain Tho2 PF11262.8 OAG15028.1 - 2.5 7.2 9.5 0.42 9.8 3.6 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ING PF12998.7 OAG15028.1 - 2.7 8.6 8.2 2.1 9.0 2.8 2.5 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding TPD52 PF04201.15 OAG15028.1 - 2.8 7.5 7.4 81 2.8 7.7 2.5 1 1 0 1 1 1 0 Tumour protein D52 family DUF4201 PF13870.6 OAG15028.1 - 3.4 7.4 14.9 0.5 10.1 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Uds1 PF15456.6 OAG15028.1 - 4.3 7.5 9.8 0.4 10.9 0.7 2.7 2 1 1 3 3 3 0 Up-regulated During Septation V_ATPase_I PF01496.19 OAG15028.1 - 4.6 5.0 7.0 6.3 4.6 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliJ PF02050.16 OAG15028.1 - 4.8 7.4 16.6 0.2 11.9 1.1 3.1 3 1 0 3 3 3 0 Flagellar FliJ protein DUF948 PF06103.11 OAG15028.1 - 7.1 7.0 6.7 3.4 8.0 1.7 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 OAG15028.1 - 7.5 7.2 16.0 18 6.0 8.6 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MFS_1 PF07690.16 OAG15029.1 - 7.1e-32 110.7 19.7 7.1e-32 110.7 19.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.21 OAG15030.1 - 1.1e-105 354.2 0.0 3.2e-105 352.7 0.0 1.6 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG15031.1 - 0.0002 20.4 35.0 0.00084 18.4 25.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 OAG15031.1 - 9.8 6.3 25.4 0.62 10.1 0.1 4.8 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III ATP-synt_G PF04718.15 OAG15032.1 - 6.4e-35 120.0 0.9 2e-34 118.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ISG65-75 PF11727.8 OAG15032.1 - 0.046 12.9 2.3 0.078 12.2 2.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.13 OAG15032.1 - 0.079 13.6 1.8 1.8 9.2 1.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Helicase_C PF00271.31 OAG15033.1 - 1.1e-23 83.6 0.0 5e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG15033.1 - 1.3e-19 70.6 0.1 4.1e-17 62.5 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OAG15033.1 - 0.0083 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold UTP25 PF06862.12 OAG15033.1 - 0.055 12.2 0.0 0.52 9.0 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyco_tranf_2_3 PF13641.6 OAG15034.1 - 1.4e-28 100.4 0.0 1.6e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG15034.1 - 2.8e-09 37.0 0.0 4.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG15034.1 - 1.3e-06 28.0 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OAG15034.1 - 0.0021 18.0 0.8 0.0021 18.0 0.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Amidohydro_2 PF04909.14 OAG15035.1 - 3.2e-11 43.6 0.1 3.4e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Clr5 PF14420.6 OAG15036.1 - 2.4e-16 59.7 2.7 4.8e-16 58.7 0.7 2.6 2 0 0 2 2 2 1 Clr5 domain adh_short_C2 PF13561.6 OAG15037.1 - 1.1e-56 192.0 0.0 2.5e-56 190.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15037.1 - 1.5e-42 145.3 0.1 3.8e-42 144.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG15037.1 - 9.2e-11 42.0 0.1 1.3e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain AAA_23 PF13476.6 OAG15038.1 - 1.7e-28 100.5 26.0 1.7e-28 100.5 26.0 8.0 2 1 2 5 5 3 1 AAA domain SMC_N PF02463.19 OAG15038.1 - 7e-10 38.7 35.7 3e-08 33.4 0.1 3.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OAG15038.1 - 4.9e-06 26.7 0.0 1.8e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 OAG15038.1 - 3.2e-05 22.8 117.5 0.0011 17.8 15.8 7.3 2 1 4 7 7 7 5 AAA domain AAA_15 PF13175.6 OAG15038.1 - 4e-05 23.5 1.4 4e-05 23.5 1.4 5.5 1 1 3 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG15038.1 - 4.6e-05 23.4 15.4 0.01 15.7 0.1 4.6 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG15038.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 OAG15038.1 - 0.0039 16.8 23.5 0.0039 16.8 23.5 8.4 2 2 5 7 7 7 1 Mechanosensitive ion channel porin domain HHH_8 PF14716.6 OAG15038.1 - 0.033 14.5 4.8 3.9 7.9 0.3 5.2 4 1 0 4 4 4 0 Helix-hairpin-helix domain AAA_22 PF13401.6 OAG15038.1 - 0.13 12.6 4.7 0.19 12.0 0.0 3.6 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 OAG15038.1 - 0.14 12.7 0.0 0.14 12.7 0.0 6.9 3 2 0 3 3 2 0 ABC transporter MtrB PF05440.12 OAG15038.1 - 1.9 9.0 5.8 36 4.9 0.0 4.7 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B GATA PF00320.27 OAG15039.1 - 2.9e-16 58.8 6.1 5.7e-16 57.8 6.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAG15039.1 - 2.4e-13 50.2 0.0 5.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG15039.1 - 1.1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG15039.1 - 1.2e-07 31.9 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 OAG15039.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OAG15039.1 - 0.00069 19.8 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 OAG15039.1 - 0.0062 16.6 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain DUF4428 PF14471.6 OAG15039.1 - 0.88 9.5 7.6 0.072 13.0 1.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Beta-lactamase PF00144.24 OAG15040.1 - 1e-39 136.7 0.0 1.6e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAG15040.1 - 5.8e-05 22.8 0.0 0.0043 16.7 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 OAG15040.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase ThiF PF00899.21 OAG15041.1 - 6.3e-59 199.3 0.0 9.9e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OAG15041.1 - 7.1e-10 39.4 0.0 3.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_7 PF13241.6 OAG15041.1 - 0.007 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Fez1 PF06818.15 OAG15041.1 - 0.0099 16.3 0.2 0.018 15.5 0.2 1.3 1 0 0 1 1 1 1 Fez1 Shikimate_DH PF01488.20 OAG15041.1 - 0.15 12.2 0.3 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FlxA PF14282.6 OAG15041.1 - 0.15 12.1 0.7 0.33 11.0 0.7 1.6 1 0 0 1 1 1 0 FlxA-like protein HET PF06985.11 OAG15042.1 - 5.4e-18 65.7 0.0 1.6e-17 64.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLX9 PF15341.6 OAG15043.1 - 2.7e-25 89.3 11.0 5.1e-25 88.4 11.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ADH_N PF08240.12 OAG15043.1 - 5.3e-07 29.5 0.0 8.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15043.1 - 0.00016 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ABC2_membrane_3 PF12698.7 OAG15044.1 - 0.098 11.7 8.4 0.12 11.5 8.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 OAG15045.1 - 6e-61 206.5 4.4 6.9e-61 206.3 4.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter GIT_SHD PF08518.11 OAG15046.1 - 0.017 14.8 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT PP2C PF00481.21 OAG15047.1 - 8.7e-35 120.6 0.0 2e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAG15047.1 - 0.15 12.0 0.0 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CLTH PF10607.9 OAG15048.1 - 4.7e-35 120.6 0.1 6.9e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 OAG15048.1 - 2.3e-23 82.6 0.2 4.2e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 OAG15048.1 - 0.013 15.4 0.1 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 LisH INO80_Ies4 PF08193.11 OAG15049.1 - 2.5e-43 148.8 19.1 3.1e-43 148.5 19.1 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Ndc1_Nup PF09531.10 OAG15049.1 - 4.7 5.8 4.8 5.4 5.6 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 OAG15050.1 - 2.6e-15 56.5 8.4 0.00024 21.8 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15050.1 - 1.2e-10 41.6 2.4 0.014 15.7 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG15050.1 - 0.0024 17.8 0.1 4.2 7.2 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OAG15050.1 - 0.033 12.7 0.1 1.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain RNA_pol_Rpb1_5 PF04998.17 OAG15051.1 - 1.3e-101 339.5 0.2 2e-101 338.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAG15051.1 - 1.6e-101 339.8 0.0 5.3e-101 338.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAG15051.1 - 6.6e-76 254.2 0.1 1.1e-75 253.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAG15051.1 - 1.6e-58 197.7 0.5 1.6e-58 197.7 0.5 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAG15051.1 - 2.3e-47 160.9 0.0 4.8e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAG15051.1 - 6.5e-44 149.2 7.0 1.2e-43 148.3 7.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAG15051.1 - 8e-33 112.6 0.0 1.8e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAG15051.1 - 1.9e-18 65.7 202.0 0.0057 17.0 10.1 14.8 9 3 6 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat CLTH PF10607.9 OAG15052.1 - 1.7e-31 109.1 0.0 3.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAG15052.1 - 5.5e-08 32.7 0.2 1.2e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 OAG15052.1 - 0.00056 19.3 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 OAG15052.1 - 0.0011 19.2 0.4 0.0021 18.3 0.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG15052.1 - 0.0012 18.7 0.2 0.0023 17.8 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG15052.1 - 0.012 15.4 0.9 0.024 14.5 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG15052.1 - 0.017 15.0 0.8 0.031 14.1 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG15052.1 - 0.021 14.7 0.4 0.04 13.8 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG15052.1 - 0.062 13.5 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG15052.1 - 0.081 12.8 0.7 0.16 11.9 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.18 OAG15053.1 - 0.022 14.9 0.0 3.3 8.0 0.0 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Glyco_transf_28 PF03033.20 OAG15054.1 - 9.6e-18 64.6 0.1 4.3e-16 59.2 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG15054.1 - 2.2e-05 23.5 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OAG15054.1 - 0.00024 21.4 0.0 0.0011 19.3 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 OAG15054.1 - 0.0023 17.9 1.9 0.0067 16.4 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase family 28 C-terminal domain Pox_VLTF3 PF04947.14 OAG15055.1 - 0.049 13.4 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like S1-P1_nuclease PF02265.16 OAG15056.1 - 4.1e-60 203.7 0.0 4.7e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Glyoxalase PF00903.25 OAG15057.1 - 1.1e-07 32.1 3.8 3.5e-07 30.5 0.9 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG15057.1 - 0.0049 17.1 0.4 0.15 12.3 0.2 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 OAG15058.1 - 9.7e-30 103.5 0.0 5.5e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15058.1 - 1.5e-20 73.8 0.0 3.1e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG15058.1 - 2.4e-06 27.2 0.3 6.7e-06 25.7 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG15058.1 - 4e-06 26.9 0.0 6.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 OAG15058.1 - 9.9e-05 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 OAG15058.1 - 0.00022 20.4 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG15058.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 OAG15059.1 - 9.1e-13 48.1 0.2 1.2e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15059.1 - 4.6e-09 36.2 0.2 5.4e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG15059.1 - 4.2e-05 23.5 0.2 7.4e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG15059.1 - 0.00027 20.9 0.1 0.00045 20.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAG15059.1 - 0.0004 20.0 2.2 0.00083 19.0 2.2 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG15059.1 - 0.0019 17.7 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG15059.1 - 0.0058 16.1 0.1 0.0089 15.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_hydro_61 PF03443.14 OAG15060.1 - 1.9e-59 201.0 0.0 2.4e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.19 OAG15061.1 - 3.1e-51 174.5 0.0 4.1e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG15061.1 - 1.8e-35 122.5 0.0 2.9e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG15061.1 - 4.9e-07 29.7 0.2 7.2e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG15061.1 - 0.00058 19.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG15061.1 - 0.0017 17.5 0.6 0.18 10.9 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG15061.1 - 0.011 16.0 1.0 0.03 14.6 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG15061.1 - 0.013 14.5 0.3 0.044 12.8 0.1 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG15061.1 - 0.022 14.0 0.3 0.85 8.8 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG15062.1 - 1.3e-24 86.7 0.0 6.3e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15062.1 - 9.3e-16 58.1 0.0 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15062.1 - 5.6e-11 42.7 0.1 8.8e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG15062.1 - 2.5e-05 23.8 0.0 0.0001 21.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG15062.1 - 6.7e-05 22.5 0.2 0.00014 21.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_9 PF01075.17 OAG15062.1 - 0.02 14.2 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) YjeF_N PF03853.15 OAG15062.1 - 0.064 13.1 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_binding_7 PF13241.6 OAG15062.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Antibiotic_NAT PF02522.14 OAG15063.1 - 0.16 11.7 0.1 0.25 11.1 0.1 1.4 1 1 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Foie-gras_1 PF11817.8 OAG15064.1 - 0.27 10.8 1.2 0.35 10.4 1.2 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 WD40 PF00400.32 OAG15065.1 - 3.7e-35 119.3 26.3 0.00011 22.9 0.3 10.9 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15065.1 - 5.5e-16 58.6 1.6 0.00026 21.2 0.0 6.5 3 3 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG15065.1 - 0.00039 20.8 11.7 0.21 12.1 0.1 5.7 7 0 0 7 7 7 2 PQQ-like domain WD40_like PF17005.5 OAG15065.1 - 0.0049 16.2 0.0 1.9 7.7 0.0 2.7 1 1 1 2 2 2 2 WD40-like domain PD40 PF07676.12 OAG15065.1 - 0.0062 16.5 2.0 15 5.7 0.1 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WI12 PF07107.11 OAG15065.1 - 0.03 14.5 0.4 3.7 7.7 0.0 3.3 2 1 1 3 3 3 0 Wound-induced protein WI12 Mcl1_mid PF12341.8 OAG15065.1 - 0.096 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region PQQ PF01011.21 OAG15065.1 - 0.14 12.1 1.1 1.1e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat DLH PF01738.18 OAG15067.1 - 5.8e-32 111.0 0.0 6.8e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG15067.1 - 0.0014 18.3 0.0 0.0088 15.7 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG15067.1 - 0.038 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 2OG-FeII_Oxy_2 PF13532.6 OAG15069.1 - 2.4e-36 125.8 0.1 3.3e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 OAG15069.1 - 2e-05 24.6 4.1 4.9e-05 23.3 4.1 1.7 1 0 0 1 1 1 1 GRF zinc finger WD40 PF00400.32 OAG15070.1 - 8.5e-14 51.7 19.3 0.019 15.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15070.1 - 0.066 13.5 0.1 4.8 7.6 0.0 3.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SAGA-Tad1 PF12767.7 OAG15071.1 - 1.4e-51 175.6 0.0 1.8e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Gcn1_N PF12074.8 OAG15072.1 - 1e-120 403.3 15.5 1.3e-119 399.7 7.9 3.7 4 0 0 4 4 4 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 OAG15072.1 - 9.1e-28 96.3 50.1 4.2e-07 30.3 0.0 18.0 17 2 4 21 21 19 9 HEAT-like repeat HEAT PF02985.22 OAG15072.1 - 7.5e-26 88.0 37.3 0.012 15.8 0.1 19.9 22 0 0 22 22 21 7 HEAT repeat HEAT_2 PF13646.6 OAG15072.1 - 1.5e-24 86.2 42.2 0.00013 22.3 3.5 14.8 10 3 6 16 16 16 8 HEAT repeats Cnd1 PF12717.7 OAG15072.1 - 1.8e-13 50.9 7.0 0.047 13.7 0.1 9.7 9 1 1 10 10 10 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OAG15072.1 - 1.2e-11 45.1 1.6 0.0058 16.8 0.1 6.3 5 0 0 5 5 5 3 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 OAG15072.1 - 1.6e-10 41.4 0.0 8.4 7.1 0.0 8.8 7 2 3 10 10 9 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAG15072.1 - 6.9e-09 35.6 0.0 0.062 12.9 0.0 6.0 3 1 2 5 5 5 2 CLASP N terminal Adaptin_N PF01602.20 OAG15072.1 - 6.2e-07 28.4 11.7 0.16 10.5 0.0 7.2 7 1 0 7 7 7 2 Adaptin N terminal region TIP120 PF08623.10 OAG15072.1 - 0.00013 21.8 0.1 0.72 9.6 0.0 6.1 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 OAG15072.1 - 0.0039 17.4 13.0 21 5.3 0.0 8.4 9 0 0 9 9 9 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 OAG15072.1 - 0.008 16.5 1.3 7.3 6.9 0.1 4.2 4 0 0 4 4 4 1 FANCI solenoid 2 DRIM PF07539.12 OAG15072.1 - 0.049 11.9 11.9 0.83 7.9 0.2 4.9 4 2 1 5 5 5 0 Down-regulated in metastasis TFCD_C PF12612.8 OAG15072.1 - 0.18 11.6 3.9 14 5.5 0.0 4.6 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal MMS19_C PF12460.8 OAG15072.1 - 0.46 9.5 28.5 0.34 10.0 0.1 7.1 8 2 2 10 10 10 0 RNAPII transcription regulator C-terminal DUF937 PF06078.11 OAG15072.1 - 0.66 10.6 11.1 72 4.0 0.4 7.0 6 2 0 6 6 6 0 Bacterial protein of unknown function (DUF937) WASH-7_C PF14746.6 OAG15072.1 - 2.3 7.9 3.8 1.8 8.2 1.3 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal HA2 PF04408.23 OAG15073.1 - 5.2e-16 58.9 0.6 1.3e-15 57.6 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG15073.1 - 1.9e-13 50.7 0.0 5.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG15073.1 - 1.1e-10 41.5 0.1 2.6e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG15073.1 - 7.6e-10 39.2 0.2 1.4e-08 35.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 OAG15073.1 - 0.002 18.5 0.3 0.0058 17.0 0.2 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 OAG15073.1 - 0.0047 17.5 0.1 0.02 15.4 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 OAG15073.1 - 0.014 15.1 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG15073.1 - 0.039 14.5 0.1 0.039 14.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 OAG15073.1 - 0.1 12.3 0.0 7.1 6.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OAG15073.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OAG15073.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAG15073.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 OAG15074.1 - 4e-05 23.2 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG15074.1 - 0.00041 21.0 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG15074.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein WD40_like PF17005.5 OAG15074.1 - 0.0058 16.0 0.2 0.037 13.4 0.0 2.3 3 0 0 3 3 3 1 WD40-like domain bZIP_1 PF00170.21 OAG15074.1 - 0.13 12.4 11.9 0.33 11.1 11.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor AAA_16 PF13191.6 OAG15074.1 - 0.15 12.4 0.0 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain bZIP_Maf PF03131.17 OAG15074.1 - 0.43 11.1 3.9 1.1 9.8 3.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG15074.1 - 0.76 9.9 10.5 1.6 8.9 10.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper TPR_1 PF00515.28 OAG15075.1 - 5.5e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG15075.1 - 0.0011 19.0 0.1 0.0027 17.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG15075.1 - 0.0021 18.3 2.3 0.094 13.0 0.2 1.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG15075.1 - 0.0032 17.5 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG15075.1 - 0.025 14.6 0.1 0.081 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG15075.1 - 0.27 12.2 2.0 4.7 8.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.11 OAG15076.1 - 1.4e-32 113.1 0.8 2.6e-32 112.2 0.5 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) KorB_C PF06613.11 OAG15076.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Pyr_redox_2 PF07992.14 OAG15077.1 - 3.6e-40 138.1 0.1 1.4e-36 126.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG15077.1 - 6.3e-11 42.7 0.0 1.2e-08 35.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG15077.1 - 0.0074 15.9 0.0 5.4 6.5 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG15077.1 - 0.045 14.0 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain T2SSL PF05134.13 OAG15077.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L FAD_binding_2 PF00890.24 OAG15077.1 - 0.16 11.0 0.0 0.74 8.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Mis14 PF08641.12 OAG15078.1 - 3.3e-12 46.9 11.2 9.4e-12 45.4 9.3 2.3 2 1 0 2 2 2 1 Kinetochore protein Mis14 like 7TMR-HDED PF07697.11 OAG15078.1 - 0.033 14.3 4.8 0.069 13.3 4.8 1.6 1 1 0 1 1 1 0 7TM-HD extracellular SPX PF03105.19 OAG15079.1 - 0.93 9.3 7.5 1 9.2 7.5 1.1 1 0 0 1 1 1 0 SPX domain RasGAP PF00616.19 OAG15080.1 - 2.2e-59 200.7 0.1 2.2e-59 200.7 0.1 2.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAG15080.1 - 9.9e-30 103.5 2.4 9.9e-30 103.5 2.4 2.8 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.11 OAG15080.1 - 0.15 11.8 1.9 0.24 11.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF724 PF05266.14 OAG15080.1 - 5.3 6.8 7.7 2.9 7.7 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPR_1 PF00515.28 OAG15081.1 - 0.065 13.1 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyrid_ox_like PF16242.5 OAG15086.1 - 2.5e-23 82.3 0.0 3.6e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAG15086.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC_tran_CTD PF16326.5 OAG15087.1 - 0.0067 16.6 4.9 0.0067 16.6 4.9 4.9 3 3 1 4 4 4 1 ABC transporter C-terminal domain GIT_CC PF16559.5 OAG15087.1 - 0.028 14.3 1.5 5.7 6.9 0.0 3.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Takusan PF04822.13 OAG15087.1 - 0.049 13.5 0.7 0.049 13.5 0.7 2.6 3 0 0 3 3 3 0 Takusan DUF4407 PF14362.6 OAG15087.1 - 0.38 10.1 33.0 0.52 9.6 13.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 OAG15087.1 - 1.5 9.3 24.8 1.2 9.6 1.3 4.2 2 1 2 4 4 4 0 Snapin/Pallidin HEM4 PF02602.15 OAG15088.1 - 5e-44 150.4 0.0 8.5e-44 149.6 0.0 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Macoilin PF09726.9 OAG15089.1 - 2.6 6.5 8.9 3.7 6.0 8.9 1.3 1 0 0 1 1 1 0 Macoilin family HeLo PF14479.6 OAG15091.1 - 9e-32 110.6 0.0 1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation HET PF06985.11 OAG15092.1 - 4.3e-23 82.3 0.3 4.8e-23 82.1 0.3 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 OAG15094.1 - 0.0036 17.6 0.2 11 6.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG15094.1 - 0.022 15.2 4.9 1.9 9.0 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OAG15094.1 - 0.064 13.8 0.8 2.4 8.8 0.0 3.4 5 0 0 5 5 5 0 Ankyrin repeats (3 copies) FRQ PF09421.10 OAG15096.1 - 1.1e-136 457.3 56.7 1.5e-136 456.9 55.8 1.6 1 1 0 1 1 1 1 Frequency clock protein COQ9 PF08511.11 OAG15097.1 - 4.9e-32 109.5 0.2 7.7e-32 108.9 0.2 1.3 1 0 0 1 1 1 1 COQ9 WD40 PF00400.32 OAG15098.1 - 2.1e-09 37.8 5.0 0.5 11.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15098.1 - 0.0051 17.1 0.0 9.8 6.6 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG15098.1 - 0.05 12.2 0.0 4.2 5.9 0.1 2.3 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF167 PF02594.16 OAG15100.1 - 2.2e-22 78.9 1.1 3.2e-22 78.4 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Arginase PF00491.21 OAG15101.1 - 3.8e-77 259.6 0.6 4.3e-77 259.3 0.6 1.0 1 0 0 1 1 1 1 Arginase family DUF4094 PF13334.6 OAG15102.1 - 0.0098 16.3 0.2 0.016 15.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) Vpu PF00558.19 OAG15102.1 - 0.044 13.5 0.4 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Vpu protein Pox_A_type_inc PF04508.12 OAG15102.1 - 0.2 11.6 2.7 0.33 10.9 0.5 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SURF6 PF04935.12 OAG15102.1 - 0.33 10.7 7.6 0.42 10.4 7.6 1.0 1 0 0 1 1 1 0 Surfeit locus protein 6 Ribosomal_L6e_N PF03868.15 OAG15104.1 - 0.0013 18.9 0.1 0.002 18.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain DUF2183 PF09949.9 OAG15105.1 - 1.6e-20 73.2 0.1 3.3e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Amidase PF01425.21 OAG15106.1 - 4.8e-65 220.3 0.0 6e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 OAG15106.1 - 7.5e-36 123.9 0.0 2e-35 122.5 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.15 OAG15107.1 - 7.9e-84 282.0 33.8 9.3e-84 281.7 33.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 OAG15108.1 - 2e-23 82.8 0.2 3.1e-23 82.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15108.1 - 3e-05 24.0 9.9 3e-05 24.0 9.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG15110.1 - 6.1e-11 42.9 0.1 8.5e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1357 PF07094.11 OAG15110.1 - 0.091 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) DUF334 PF03904.13 OAG15111.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RIH_assoc PF08454.11 OAG15111.1 - 0.2 11.5 1.0 0.28 11.0 1.0 1.5 1 1 0 1 1 1 0 RyR and IP3R Homology associated T3SS_needle_E PF08988.10 OAG15111.1 - 1.1 9.5 5.1 0.39 10.9 0.4 2.6 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle IR1-M PF12185.8 OAG15112.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain pP_pnuc_1 PF18165.1 OAG15112.1 - 0.22 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease DUF3328 PF11807.8 OAG15114.1 - 1.1e-31 110.4 3.7 1.2e-31 110.2 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4024 PF13216.6 OAG15116.1 - 0.0065 16.4 3.4 28 4.8 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF4024) Peptidase_S28 PF05577.12 OAG15117.1 - 7.2e-43 147.0 0.2 1e-41 143.2 0.2 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 NIF PF03031.18 OAG15118.1 - 1.5e-25 89.8 0.2 2.6e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OAG15118.1 - 2.5e-08 34.2 0.0 6.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG15118.1 - 1.4e-06 28.1 0.1 3.4e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OAG15118.1 - 8.7e-05 22.9 0.7 0.00019 21.8 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG15118.1 - 0.055 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OAG15118.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Zn_clus PF00172.18 OAG15119.1 - 8e-08 32.3 7.8 8e-08 32.3 7.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG15119.1 - 2.4e-05 23.5 0.6 0.0001 21.4 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.7 OAG15119.1 - 0.00067 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like zn-ribbon_14 PF16503.5 OAG15119.1 - 0.14 11.7 0.6 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon Ribosomal_L11_N PF03946.14 OAG15120.1 - 1.9e-26 91.7 0.1 4.1e-26 90.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAG15120.1 - 1e-23 83.6 2.1 3e-23 82.1 2.1 1.8 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SNF2_N PF00176.23 OAG15121.1 - 4.7e-57 193.3 0.0 7.9e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAG15121.1 - 7e-55 186.0 0.5 2e-54 184.5 0.4 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 OAG15121.1 - 3.5e-15 56.3 0.0 1.1e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG15121.1 - 7.8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OB_NTP_bind PF07717.16 OAG15122.1 - 6.2e-19 68.1 0.0 1.4e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG15122.1 - 7.2e-17 61.6 0.2 5e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG15122.1 - 7.1e-14 52.1 0.0 2.3e-13 50.4 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG15122.1 - 4.8e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG15122.1 - 1.3e-05 25.5 0.0 4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG15122.1 - 0.0013 19.0 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG15122.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG15122.1 - 0.002 17.2 0.0 0.0047 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 OAG15122.1 - 0.014 15.4 0.0 0.086 12.8 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 OAG15122.1 - 0.022 14.4 0.0 0.073 12.7 0.0 1.9 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DAP3 PF10236.9 OAG15122.1 - 0.042 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 OAG15122.1 - 0.047 14.2 1.2 0.13 12.8 0.0 2.3 1 1 1 2 2 2 0 ABC transporter AAA_16 PF13191.6 OAG15122.1 - 0.066 13.6 0.8 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAG15122.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG15122.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAG15122.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IATP PF04568.12 OAG15122.1 - 6.7 7.2 7.8 2.3 8.7 2.0 2.8 3 0 0 3 3 2 0 Mitochondrial ATPase inhibitor, IATP PALP PF00291.25 OAG15123.1 - 2.9e-55 187.8 0.6 3.4e-55 187.5 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBP_bac_8 PF13416.6 OAG15123.1 - 0.013 15.4 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Metallophos_2 PF12850.7 OAG15123.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EI24 PF07264.11 OAG15124.1 - 8e-10 39.2 12.5 1.3e-09 38.6 12.5 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Asp PF00026.23 OAG15125.1 - 9.3e-108 360.4 0.1 1.1e-107 360.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG15125.1 - 3e-16 60.2 2.7 3.6e-14 53.4 1.9 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG15125.1 - 7.8e-05 23.2 0.1 1 10.0 0.0 3.1 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 OAG15125.1 - 0.00011 22.0 0.0 0.0019 18.0 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAG15125.1 - 0.0032 18.0 0.0 2.8 8.6 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease GRAM PF02893.20 OAG15126.1 - 3.8e-29 100.9 3.9 1.2e-18 67.1 0.2 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 OAG15126.1 - 4.6e-27 94.7 0.0 1e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 OAG15126.1 - 5.5e-15 55.8 0.0 1.8e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OAG15126.1 - 4.1e-06 27.1 0.1 1.1e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 OAG15126.1 - 7.1e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 OAG15126.1 - 0.0016 18.6 0.0 0.0051 16.9 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_2 PF08458.10 OAG15126.1 - 0.0084 16.4 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region RED_N PF07808.13 OAG15127.1 - 9.7e-06 25.3 5.9 9.7e-06 25.3 5.9 2.5 3 0 0 3 3 3 1 RED-like protein N-terminal region GvpG PF05120.12 OAG15127.1 - 0.068 13.2 0.4 0.068 13.2 0.4 2.5 2 0 0 2 2 2 0 Gas vesicle protein G Glyco_hydro_43 PF04616.14 OAG15128.1 - 1.7e-39 135.8 10.9 2.1e-39 135.6 10.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CENP-T_C PF15511.6 OAG15129.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG15129.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG15129.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG15129.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG15129.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG15129.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG15129.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OAG15129.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 OAG15129.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 OAG15130.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAG15130.1 - 6e-06 26.5 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OAG15130.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OAG15130.1 - 4.3e-05 23.6 0.3 7.9e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAG15130.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG15130.1 - 0.028 14.5 0.2 0.048 13.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AhpC-TSA PF00578.21 OAG15131.1 - 0.00029 20.7 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OAG15131.1 - 0.0068 16.5 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Exo5 PF09810.9 OAG15132.1 - 1.7e-127 426.0 0.0 2.6e-126 422.1 0.0 2.2 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 OAG15132.1 - 1.6e-07 31.5 0.0 0.0033 17.4 0.0 2.5 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Hydrolase PF00702.26 OAG15133.1 - 4.7e-09 36.8 0.0 7.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG15133.1 - 5.1e-09 36.5 0.0 9.9e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG15133.1 - 1.7e-07 31.2 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like AMP-binding PF00501.28 OAG15134.1 - 3.3e-78 263.2 0.0 4.2e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG15134.1 - 2.1e-16 59.5 3.6 2.1e-16 59.5 3.6 2.3 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG15134.1 - 7.8e-15 55.6 0.0 1.7e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 OAG15135.1 - 2.3e-52 176.8 0.1 7e-52 175.3 0.1 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG15135.1 - 1e-18 67.7 0.0 1.2e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG15135.1 - 0.00021 20.8 0.0 0.00077 19.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OAG15135.1 - 0.015 14.8 0.2 0.21 11.1 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG15135.1 - 0.017 14.7 0.1 2.9 7.4 0.1 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG15135.1 - 0.017 15.0 0.0 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 OAG15135.1 - 0.059 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 OAG15135.1 - 0.066 13.3 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG15135.1 - 0.071 13.5 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Transferase PF02458.15 OAG15136.1 - 7.5e-22 77.6 0.0 1.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Transferase family DNase_NucA_NucB PF14040.6 OAG15139.1 - 1.7e-13 51.0 0.1 2.6e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB AIM24 PF01987.17 OAG15141.1 - 1.4e-53 181.7 0.2 1.8e-53 181.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF1983 PF09327.11 OAG15141.1 - 0.07 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1983) XPB_DRD PF18458.1 OAG15141.1 - 0.11 12.3 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain ABC_membrane PF00664.23 OAG15142.1 - 5.6e-43 147.6 12.3 7e-43 147.2 12.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG15142.1 - 5.5e-35 120.9 0.0 1e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG15142.1 - 9e-07 28.5 0.0 0.00024 20.6 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG15142.1 - 1.3e-05 25.7 0.1 3.1e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OAG15142.1 - 0.00051 20.1 0.0 0.013 15.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG15142.1 - 0.0014 18.9 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG15142.1 - 0.0046 16.8 0.1 0.033 14.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAG15142.1 - 0.0049 17.3 0.0 0.03 14.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG15142.1 - 0.015 14.6 0.0 0.048 12.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 OAG15142.1 - 0.015 15.3 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG15142.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAG15142.1 - 0.018 14.8 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 OAG15142.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 OAG15142.1 - 0.027 14.1 0.2 0.094 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAG15142.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 OAG15142.1 - 0.029 14.9 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OAG15142.1 - 0.03 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_1 PF00515.28 OAG15142.1 - 0.032 14.1 1.5 0.081 12.8 1.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.12 OAG15142.1 - 0.036 14.0 0.0 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 OAG15142.1 - 0.043 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAG15142.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OAG15142.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_10 PF12846.7 OAG15142.1 - 0.059 12.3 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.6 OAG15142.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG15142.1 - 0.063 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG15142.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OAG15142.1 - 0.15 12.3 0.7 0.59 10.4 0.6 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat AAA_15 PF13175.6 OAG15142.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TPR_11 PF13414.6 OAG15142.1 - 0.19 11.4 0.6 0.42 10.3 0.6 1.6 1 0 0 1 1 1 0 TPR repeat HET PF06985.11 OAG15143.1 - 3.3e-27 95.6 0.0 5.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG15146.1 - 4.4e-59 199.2 2.9 2.2e-40 138.2 3.2 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15146.1 - 3.7e-44 151.0 0.3 3.6e-31 108.5 0.4 2.5 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15146.1 - 4.6e-11 42.9 0.8 7.8e-11 42.2 0.8 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG15146.1 - 0.0032 16.8 0.2 0.0075 15.6 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HCO3_cotransp PF00955.21 OAG15147.1 - 5.2e-86 289.5 13.0 2.6e-46 158.5 5.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Amino_oxidase PF01593.24 OAG15148.1 - 2.8e-37 129.1 0.0 5.9e-37 128.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG15148.1 - 1.1e-05 25.6 0.0 3.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 OAG15149.1 - 1.2e-40 139.6 0.0 1.8e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15149.1 - 3.6e-27 95.3 0.0 5.4e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 OAG15149.1 - 0.0041 17.4 5.3 0.0082 16.5 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG15149.1 - 0.009 15.8 5.2 0.016 15.0 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 OAG15149.1 - 0.046 13.0 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like zf-RING_10 PF16685.5 OAG15149.1 - 0.047 13.8 2.4 0.09 12.9 2.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 OAG15149.1 - 4 7.4 5.5 7.5 6.5 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG15149.1 - 6.4 6.8 5.7 13 5.8 5.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain HET PF06985.11 OAG15150.1 - 1.7e-29 103.1 0.3 3.2e-29 102.2 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 OAG15152.1 - 6.6e-09 36.0 0.0 1.8e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain CN_hydrolase PF00795.22 OAG15153.1 - 2.6e-24 86.0 0.0 3.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Melibiase PF02065.18 OAG15153.1 - 0.00047 19.2 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase NADHdh_A3 PF14987.6 OAG15153.1 - 0.023 15.0 0.1 0.26 11.6 0.1 2.6 3 0 0 3 3 3 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 bZIP_1 PF00170.21 OAG15155.1 - 8.6e-09 35.4 9.2 1.7e-08 34.4 9.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG15155.1 - 0.0007 19.6 8.7 0.0013 18.7 8.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG15155.1 - 0.0022 18.4 5.5 0.0064 17.0 5.5 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor GvpL_GvpF PF06386.11 OAG15155.1 - 0.0023 17.9 1.4 0.0041 17.1 1.4 1.4 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF Sad1_UNC PF07738.13 OAG15155.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal NmrA PF05368.13 OAG15156.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG15156.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_8 PF13450.6 OAG15159.1 - 0.00046 20.4 0.4 0.0031 17.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG15159.1 - 0.0041 17.2 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAG15159.1 - 0.032 13.5 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG15159.1 - 0.033 13.5 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG15159.1 - 0.063 13.3 0.1 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding MOZ_SAS PF01853.18 OAG15160.1 - 1e-66 224.0 0.0 1.5e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG15160.1 - 5.7e-16 57.9 0.0 1.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_1 PF00583.25 OAG15160.1 - 0.0055 16.9 0.0 0.06 13.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG15160.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG15160.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Helicase_C_2 PF13307.6 OAG15161.1 - 5.4e-54 182.9 0.0 1.6e-53 181.4 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAG15161.1 - 3.5e-48 163.5 0.0 6.1e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OAG15161.1 - 0.0015 18.6 0.0 0.81 9.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG15161.1 - 0.0099 15.7 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 OAG15161.1 - 0.068 12.6 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 OAG15161.1 - 0.11 12.8 0.3 4.9 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain PTR2 PF00854.21 OAG15162.1 - 3.5e-84 282.9 8.2 4.9e-84 282.4 8.2 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG15163.1 - 2.5e-40 138.5 32.2 2.5e-40 138.5 32.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15163.1 - 5.8e-13 48.5 7.0 5.8e-13 48.5 7.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAG15163.1 - 5.1e-08 31.8 0.3 5.1e-08 31.8 0.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Antirestrict PF03230.13 OAG15163.1 - 0.081 13.0 0.2 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Antirestriction protein DUF1294 PF06961.13 OAG15163.1 - 0.11 12.7 0.1 0.53 10.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1294) SnoaL_4 PF13577.6 OAG15164.1 - 5.2e-05 23.4 0.4 7.2e-05 22.9 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG15164.1 - 0.036 14.7 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_1 PF00561.20 OAG15165.1 - 1.6e-22 80.4 0.0 3.7e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG15165.1 - 4.6e-16 60.1 0.0 5.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG15165.1 - 0.0002 20.7 0.0 0.084 12.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 OAG15165.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 OAG15165.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HET PF06985.11 OAG15166.1 - 1.5e-24 87.0 0.2 2e-24 86.6 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_rhamnosid6H PF17389.2 OAG15167.1 - 7.5e-67 226.0 0.6 1e-66 225.5 0.6 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OAG15167.1 - 4.8e-38 130.7 0.7 2.8e-19 69.6 0.4 2.5 2 0 0 2 2 2 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OAG15167.1 - 3.6e-19 68.6 0.0 8.3e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OAG15167.1 - 6.8e-12 45.0 0.1 2.2e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain NACHT PF05729.12 OAG15168.1 - 2.9e-25 89.1 0.0 5.4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 OAG15168.1 - 2.4e-22 79.0 3.7 0.00036 20.8 0.4 7.4 4 3 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG15168.1 - 2.5e-17 62.9 29.3 1.7e-06 28.7 1.2 10.0 10 0 0 10 10 10 5 WD domain, G-beta repeat HET PF06985.11 OAG15168.1 - 5e-14 52.9 9.2 7.6e-12 45.8 0.2 3.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Nbas_N PF15492.6 OAG15168.1 - 0.00073 19.0 6.2 5.3 6.3 0.1 5.5 3 1 4 7 7 7 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OAG15168.1 - 0.0017 17.1 9.6 1.9 7.0 0.1 5.7 3 2 3 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG15168.1 - 0.07 12.4 0.0 3.4 6.9 0.0 2.6 1 1 0 2 2 2 0 WD40-like domain IKI3 PF04762.12 OAG15168.1 - 0.12 10.4 1.9 1.4 6.8 0.3 3.3 5 0 0 5 5 5 0 IKI3 family Glyoxalase PF00903.25 OAG15169.1 - 1e-13 51.6 0.1 1.6e-13 50.9 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 OAG15169.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal BtrH_N PF14399.6 OAG15169.1 - 0.019 15.2 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal Glyoxalase_6 PF18029.1 OAG15169.1 - 0.058 14.2 0.0 0.38 11.6 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain HET PF06985.11 OAG15170.1 - 2.2e-26 93.0 0.0 4.2e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trimer_CC PF08954.11 OAG15171.1 - 0.1 12.2 0.3 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 Trimerisation motif Spc7_N PF15402.6 OAG15171.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FtsJ PF01728.19 OAG15172.1 - 9.2e-13 48.7 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase SecE PF00584.20 OAG15173.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Abhydrolase_3 PF07859.13 OAG15175.1 - 5.8e-22 78.6 0.0 8.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG15175.1 - 4.1e-05 22.6 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAG15175.1 - 0.013 14.8 0.1 0.099 11.9 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 OAG15175.1 - 0.064 12.9 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase HTH_psq PF05225.16 OAG15177.1 - 0.00092 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_49 PF18010.1 OAG15177.1 - 0.047 13.5 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain DUF4419 PF14388.6 OAG15179.1 - 7e-106 354.0 0.0 8.1e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) NACHT PF05729.12 OAG15181.1 - 1e-08 35.3 0.4 1.9e-07 31.1 0.0 2.7 3 0 0 3 3 3 1 NACHT domain SesA PF17107.5 OAG15181.1 - 2.4e-07 30.9 1.5 2.9e-06 27.5 0.1 2.7 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 OAG15181.1 - 1.8e-06 28.4 0.2 2.7e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG15181.1 - 2.8e-06 27.7 0.1 4.2e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG15181.1 - 0.0017 18.8 0.1 0.011 16.3 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 OAG15181.1 - 0.0043 17.6 0.0 0.036 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG15181.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG15181.1 - 0.0053 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 OAG15181.1 - 0.0074 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAG15181.1 - 0.0087 16.4 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.18 OAG15181.1 - 0.021 14.5 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 OAG15181.1 - 0.037 14.4 0.0 0.49 10.8 0.0 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAG15181.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OAG15181.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 OAG15181.1 - 0.072 13.6 0.1 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OAG15181.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 OAG15181.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OAG15181.1 - 0.12 12.4 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OAG15181.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 NTPase p450 PF00067.22 OAG15182.1 - 1.6e-47 162.3 0.0 1.9e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 OAG15183.1 - 4.2e-27 94.6 3.7 6.9e-27 93.9 3.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG15183.1 - 3.9e-09 36.5 0.0 8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.6 OAG15185.1 - 7.8e-22 77.9 0.0 2.9e-21 76.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15185.1 - 2.6e-14 53.7 0.0 1.5e-13 51.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15185.1 - 1.5e-12 48.0 0.0 3.7e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15185.1 - 7.6e-12 45.3 0.0 8.9e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG15185.1 - 1.7e-10 41.5 0.0 1.6e-09 38.4 0.0 2.5 2 2 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG15185.1 - 6.5e-08 32.2 0.0 5.7e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAG15185.1 - 0.00067 19.1 0.0 0.00098 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG15185.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG15185.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MmoB_DmpM PF02406.17 OAG15185.1 - 0.027 14.7 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 MmoB/DmpM family FtsJ PF01728.19 OAG15185.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 OAG15185.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 OAG15186.1 - 2.3e-67 227.8 0.0 2.9e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG15189.1 - 5.3e-40 137.5 0.0 6.8e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF_4EBP PF05456.11 OAG15189.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Cys_Met_Meta_PP PF01053.20 OAG15190.1 - 5.3e-128 426.8 0.0 6.2e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG15190.1 - 2.2e-08 33.7 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG15190.1 - 6.4e-08 31.9 0.0 2.1e-07 30.2 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG15190.1 - 0.00022 20.7 0.0 0.00051 19.5 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 OAG15190.1 - 0.041 12.4 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.16 OAG15190.1 - 0.057 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Pim PF16765.5 OAG15191.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Pesticin immunity protein adh_short PF00106.25 OAG15192.1 - 3.7e-28 98.3 0.1 6.1e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15192.1 - 2.7e-22 79.5 0.0 3.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG15192.1 - 3.7e-05 23.3 0.0 8.6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG15192.1 - 0.014 15.3 0.5 0.89 9.4 0.3 2.8 1 1 1 2 2 2 0 KR domain p450 PF00067.22 OAG15193.1 - 1.7e-65 221.6 0.0 2.2e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.20 OAG15194.1 - 9.3e-14 51.8 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 OAG15195.1 - 1.1e-09 38.3 8.8 2e-09 37.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG15196.1 - 5.1e-64 216.7 0.0 7.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 OAG15198.1 - 1.7e-25 90.1 0.0 3e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPX PF03105.19 OAG15200.1 - 0.037 14.0 1.9 0.045 13.7 1.9 1.2 1 0 0 1 1 1 0 SPX domain PAN_4 PF14295.6 OAG15201.1 - 0.0058 16.5 2.0 1.1 9.2 0.2 2.6 2 0 0 2 2 2 2 PAN domain HET PF06985.11 OAG15202.1 - 4.9e-27 95.1 0.0 1.1e-26 94.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.18 OAG15204.1 - 2.3e-41 141.8 27.8 2.7e-41 141.6 27.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAG15204.1 - 1.1e-06 27.9 12.0 1.1e-06 27.9 12.0 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 OAG15204.1 - 3.2 6.5 22.5 0.26 10.1 15.2 2.4 2 1 0 2 2 2 0 Spore germination protein Fungal_trans_2 PF11951.8 OAG15205.1 - 2.3e-07 30.0 7.1 1.1e-06 27.7 7.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15205.1 - 7.6e-07 29.2 7.4 7.6e-07 29.2 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG15206.1 - 6.9e-19 68.1 0.5 7.1e-18 64.8 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15206.1 - 5.9e-11 42.4 0.3 1.7e-10 40.8 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15206.1 - 5.3e-05 23.2 0.1 9.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG15206.1 - 0.0028 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG15206.1 - 0.0072 15.5 0.1 0.0099 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG15206.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2585 PF10755.9 OAG15208.1 - 0.026 14.2 0.5 0.047 13.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2585) Tlr3_TMD PF17968.1 OAG15208.1 - 1.2 9.3 0.1 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Peptidase_S8 PF00082.22 OAG15209.1 - 2.5e-32 112.3 9.1 3e-32 112.1 9.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG15209.1 - 5.7e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3638 PF12340.8 OAG15210.1 - 5.1e-89 297.5 0.2 8.9e-89 296.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG15210.1 - 4.2e-15 54.8 0.1 8e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Ribosomal_S27e PF01667.17 OAG15210.1 - 0.057 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 SMP PF04927.12 OAG15211.1 - 0.00031 21.2 0.3 0.00038 20.9 0.3 1.2 1 0 0 1 1 1 1 Seed maturation protein zf-met PF12874.7 OAG15212.1 - 7e-10 39.0 18.3 0.00011 22.4 1.9 5.0 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG15212.1 - 4.3e-09 36.4 20.2 0.034 15.0 0.5 6.6 5 1 1 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG15212.1 - 7.4e-09 35.7 19.4 0.00016 21.9 1.4 4.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG15212.1 - 3.4e-08 33.5 22.5 0.027 14.9 2.0 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG15212.1 - 1.3e-06 28.7 23.4 0.006 16.9 0.6 5.1 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OAG15212.1 - 1.5e-06 28.1 14.3 0.0048 16.9 0.8 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-DNA_Pol PF08996.10 OAG15212.1 - 0.0018 18.1 4.3 0.041 13.6 0.2 2.3 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger Rad50_zn_hook PF04423.14 OAG15212.1 - 0.028 14.2 0.6 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 OAG15212.1 - 1.4 8.9 12.5 31 4.6 0.4 3.7 2 2 0 2 2 2 0 zinc-ribbons AKAP95 PF04988.12 OAG15212.1 - 2 8.6 11.2 1.7 8.9 0.4 3.8 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) DUF393 PF04134.12 OAG15212.1 - 2.6 9.4 6.4 21 6.5 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF393 Zn-ribbon_8 PF09723.10 OAG15212.1 - 4.2 7.6 18.5 8.3 6.6 0.6 4.9 3 2 2 5 5 5 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 OAG15212.1 - 7 7.3 24.0 6 7.5 0.3 5.3 5 1 0 5 5 5 0 Zinc-finger double domain LRR_4 PF12799.7 OAG15213.1 - 0.091 13.2 0.1 19 5.8 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) A_deaminase PF00962.22 OAG15214.1 - 6.1e-23 81.7 0.0 8.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 OAG15215.1 - 7.4e-43 146.0 0.1 1.9e-41 141.4 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 OAG15215.1 - 2.4e-26 91.9 0.2 1.7e-25 89.2 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 OAG15215.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal TACC_C PF05010.14 OAG15217.1 - 0.013 15.3 0.7 0.02 14.7 0.7 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_14 PF13428.6 OAG15217.1 - 0.062 14.1 0.4 0.48 11.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Rab3-GTPase_cat PF13890.6 OAG15217.1 - 0.073 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Osmo_CC PF08946.10 OAG15217.1 - 0.083 13.1 2.4 0.49 10.7 0.1 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TEX12 PF15219.6 OAG15217.1 - 0.084 13.2 0.5 1.5 9.2 0.4 2.7 1 1 1 2 2 2 0 Testis-expressed 12 ApoB100_C PF12491.8 OAG15217.1 - 0.094 12.7 0.4 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal COPI_assoc PF08507.10 OAG15217.1 - 0.18 11.8 2.6 0.25 11.4 2.6 1.2 1 0 0 1 1 1 0 COPI associated protein MFS_1 PF07690.16 OAG15218.1 - 8.9e-37 126.8 31.6 8.9e-37 126.8 31.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 OAG15218.1 - 3.1e-05 24.3 3.0 0.026 14.8 0.0 3.4 2 1 0 3 3 3 2 Domain of unknown function (DUF1772) CSN8_PSD8_EIF3K PF10075.9 OAG15220.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family UQ_con PF00179.26 OAG15222.1 - 9.4e-49 164.7 0.0 1.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG15222.1 - 0.0043 16.9 0.1 0.0067 16.3 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 OAG15222.1 - 0.16 12.2 0.2 0.24 11.7 0.2 1.4 1 1 0 1 1 1 0 RWD domain DUF2237 PF09996.9 OAG15226.1 - 9.7e-40 135.1 0.1 1.2e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Phospholip_A2_3 PF09056.11 OAG15227.1 - 2e-29 102.5 1.6 2.7e-29 102.0 1.6 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Phage_base_V PF04717.12 OAG15227.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector DUF155 PF02582.14 OAG15228.1 - 1.2e-54 185.0 0.0 1.2e-54 185.0 0.0 1.8 3 0 0 3 3 3 1 Uncharacterised ACR, YagE family COG1723 TsaE PF02367.17 OAG15228.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RGS PF00615.19 OAG15229.1 - 1.6e-14 54.2 0.1 1.2e-12 48.2 0.1 2.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain 2OG-FeII_Oxy_3 PF13640.6 OAG15230.1 - 5.3e-11 43.3 0.1 8.8e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RING_2 PF13639.6 OAG15231.1 - 1.9e-08 34.5 2.8 3.6e-08 33.6 2.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG15231.1 - 5.6e-06 26.3 2.6 0.0001 22.3 0.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG15231.1 - 2.6e-05 24.1 1.8 4.7e-05 23.2 1.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG15231.1 - 0.00018 21.3 0.8 0.00048 19.9 0.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG15231.1 - 0.00082 19.2 0.8 0.0016 18.3 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG15231.1 - 0.0019 18.0 2.3 0.0034 17.2 2.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG15231.1 - 0.0043 17.3 2.9 0.0085 16.4 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG15231.1 - 0.009 15.8 3.5 0.021 14.6 3.5 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 OAG15231.1 - 0.012 15.4 3.6 0.026 14.4 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OAG15231.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 OAG15231.1 - 0.03 14.5 0.3 0.079 13.1 0.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DDR PF08841.10 OAG15232.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OAG15232.1 - 0.22 9.7 0.0 0.29 9.3 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein PGAP1 PF07819.13 OAG15233.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein VSP PF03302.13 OAG15233.1 - 0.022 13.6 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Amnionless PF14828.6 OAG15233.1 - 0.081 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Amnionless FeoB_associated PF12669.7 OAG15233.1 - 0.14 12.6 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Gram_pos_anchor PF00746.21 OAG15233.1 - 0.75 9.8 3.3 1.8 8.5 3.3 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif zf-Tim10_DDP PF02953.15 OAG15235.1 - 4.2e-20 71.2 2.3 5.1e-20 70.9 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TrbI_Ftype PF09677.10 OAG15236.1 - 0.22 11.8 0.5 1 9.7 0.2 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) GWT1 PF06423.12 OAG15237.1 - 2.3e-41 141.4 4.9 6.9e-41 139.8 4.9 1.8 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 OAG15237.1 - 0.0055 17.2 0.0 0.0055 17.2 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) DUF4896 PF16237.5 OAG15237.1 - 0.0077 16.1 1.5 0.23 11.3 0.9 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4896) DAO PF01266.24 OAG15238.1 - 9.8e-20 71.4 0.0 4.3e-19 69.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAG15238.1 - 0.0083 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 OAG15238.1 - 0.043 13.3 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 OAG15238.1 - 0.052 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 OAG15239.1 - 4.5e-26 91.5 0.4 6.6e-26 90.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15239.1 - 3.1e-09 36.8 9.6 5.7e-09 35.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 OAG15240.1 - 9.3e-41 139.8 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG15240.1 - 6.9e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UDPGP PF01704.18 OAG15241.1 - 2.9e-60 204.1 0.0 3.8e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.6 OAG15241.1 - 0.029 14.1 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF5425 PF17472.2 OAG15241.1 - 0.13 13.1 0.7 19 6.1 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5425) HHH_5 PF14520.6 OAG15242.1 - 5.3e-07 30.1 0.2 1e-06 29.2 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 OAG15242.1 - 0.098 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain adh_short PF00106.25 OAG15243.1 - 5.4e-46 156.5 0.8 7.2e-46 156.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15243.1 - 1.6e-31 109.7 0.4 2.1e-31 109.3 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15243.1 - 6.7e-08 32.7 1.0 1.6e-07 31.5 1.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG15243.1 - 3.6e-06 26.3 0.7 6.3e-06 25.5 0.7 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG15243.1 - 0.0066 15.9 1.9 0.013 15.0 0.4 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG15243.1 - 0.016 14.5 0.0 0.046 13.1 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 OAG15243.1 - 0.025 14.7 0.5 0.044 13.8 0.5 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG15243.1 - 0.036 13.4 0.1 0.072 12.4 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GvpG PF05120.12 OAG15244.1 - 0.47 10.5 4.5 1.3 9.1 4.5 1.8 1 1 0 1 1 1 0 Gas vesicle protein G Mei5 PF10376.9 OAG15244.1 - 3.7 7.3 25.5 38 4.1 2.3 3.5 2 1 1 3 3 3 0 Double-strand recombination repair protein Tyrosinase PF00264.20 OAG15245.1 - 2.2e-44 152.4 2.5 3.2e-44 151.9 2.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BTB PF00651.31 OAG15248.1 - 4.6e-08 33.3 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.27 OAG15249.1 - 2.2e-12 47.4 0.0 4.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAG15249.1 - 0.0097 16.0 2.0 0.15 12.3 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG15249.1 - 0.011 16.3 0.6 0.16 12.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3836 PF12930.7 OAG15249.1 - 0.056 13.2 0.7 0.12 12.1 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF3836) DUF1376 PF07120.11 OAG15249.1 - 0.079 13.3 0.1 0.26 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) TPR_1 PF00515.28 OAG15249.1 - 0.13 12.1 1.4 0.33 10.8 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 OAG15250.1 - 1.4e-53 180.1 1.9 1.7e-53 179.8 1.9 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A ECH_1 PF00378.20 OAG15251.1 - 1.2e-42 145.9 0.0 1.6e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG15251.1 - 4.7e-22 78.9 0.1 6.6e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Nucleopor_Nup85 PF07575.13 OAG15252.1 - 1.6e-24 86.4 1.5 4.3e-17 61.9 0.1 2.6 3 0 0 3 3 3 2 Nup85 Nucleoporin PBP1_TM PF14812.6 OAG15252.1 - 0.065 13.6 3.2 0.15 12.5 3.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAG15252.1 - 0.95 9.9 11.8 13 6.2 12.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ysc84 PF04366.12 OAG15253.1 - 7.2e-45 151.9 0.0 1.1e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator RRP7 PF12923.7 OAG15254.1 - 3.1e-31 108.0 2.9 6.1e-31 107.0 2.9 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAG15254.1 - 9.6e-22 77.5 0.0 2.2e-21 76.3 0.0 1.6 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 OAG15254.1 - 0.031 14.1 1.7 2.7 7.9 0.0 3.2 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 OAG15255.1 - 2.5e-42 145.1 0.0 3.9e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15255.1 - 7e-24 84.5 0.0 1.3e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 OAG15255.1 - 2.1e-16 60.6 0.0 1.3e-15 58.0 0.0 2.5 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.14 OAG15255.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TRAP_alpha PF03896.16 OAG15256.1 - 0.073 12.3 2.7 0.1 11.8 2.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3402 PF11882.8 OAG15256.1 - 0.19 10.8 3.3 0.27 10.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) BUD22 PF09073.10 OAG15256.1 - 0.26 10.6 7.7 0.34 10.2 7.7 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 OAG15256.1 - 0.49 8.4 3.6 0.69 7.9 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 OAG15256.1 - 1.2 8.5 11.2 1.5 8.2 11.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAG15256.1 - 4.1 5.5 11.2 5 5.2 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Catalase PF00199.19 OAG15257.1 - 3.9e-173 576.0 0.4 6.2e-173 575.3 0.4 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG15257.1 - 1.5e-16 60.4 0.1 2.8e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 OAG15257.1 - 4.1e-09 36.3 0.9 8.5e-09 35.2 0.9 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 OAG15257.1 - 2.3e-08 34.0 0.1 4.4e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family MMM1 PF10296.9 OAG15260.1 - 0.00012 21.3 0.0 0.00074 18.7 0.0 2.3 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SPX PF03105.19 OAG15260.1 - 5.9 6.7 11.7 9.7 6.0 11.7 1.3 1 0 0 1 1 1 0 SPX domain HET PF06985.11 OAG15262.1 - 2.3e-28 99.4 0.0 4.3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HTH_33 PF13592.6 OAG15262.1 - 0.11 12.1 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Response_reg PF00072.24 OAG15263.1 - 4.4e-25 88.0 0.1 8.1e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG15263.1 - 7e-23 81.3 0.1 1.4e-21 77.1 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG15263.1 - 1.8e-13 50.3 0.0 4.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 OAG15263.1 - 0.0067 16.8 1.1 1.4 9.4 0.1 3.1 3 0 0 3 3 3 1 HAMP domain VGCC_alpha2 PF08473.11 OAG15263.1 - 0.037 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd GST_N_3 PF13417.6 OAG15266.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG15266.1 - 2.9e-06 27.5 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG15266.1 - 0.0056 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG15266.1 - 0.027 14.7 0.1 0.074 13.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG15266.1 - 0.037 14.0 0.1 0.27 11.3 0.0 2.1 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Fibrillarin_2 PF10113.9 OAG15266.1 - 0.095 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein ArsB PF02040.15 OAG15269.1 - 4.2e-14 52.7 19.3 4.8e-10 39.4 5.4 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Esterase_phd PF10503.9 OAG15271.1 - 3.3e-21 75.8 0.1 4.3e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG15271.1 - 4.2e-06 26.4 0.1 6.5e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG15271.1 - 0.00012 21.8 0.7 0.00017 21.3 0.6 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG15271.1 - 0.0023 17.6 0.6 0.0034 17.1 0.6 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OAG15271.1 - 0.003 17.5 0.1 0.0038 17.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAG15271.1 - 0.0073 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Eno-Rase_NADH_b PF12242.8 OAG15271.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2920 PF11144.8 OAG15271.1 - 0.043 13.0 0.3 0.065 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 OAG15271.1 - 0.044 13.7 0.2 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 OAG15271.1 - 0.044 12.6 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.12 OAG15271.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_61 PF03443.14 OAG15272.1 - 5.6e-30 104.8 0.1 6.9e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TIP39 PF14980.6 OAG15273.1 - 0.056 13.3 1.0 0.13 12.2 1.0 1.7 1 0 0 1 1 1 0 TIP39 peptide FAM199X PF15814.5 OAG15273.1 - 0.35 9.9 2.4 0.58 9.2 2.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X HET PF06985.11 OAG15274.1 - 6.5e-27 94.7 0.0 8.2e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 OAG15275.1 - 1.7e-16 61.5 0.0 2.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG15275.1 - 1.5e-06 28.1 0.1 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3669 PF12417.8 OAG15276.1 - 2.2e-09 37.4 0.0 3.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Zinc finger protein TFB6 PF17110.5 OAG15278.1 - 5e-55 185.9 0.1 6.2e-55 185.6 0.1 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Bul1_N PF04425.12 OAG15279.1 - 1.8e-07 30.3 2.2 8.5e-07 28.1 0.6 2.3 1 1 1 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.29 OAG15279.1 - 8.9e-06 25.8 0.0 3.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG15279.1 - 2.6e-05 23.8 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Tmemb_14 PF03647.13 OAG15280.1 - 8.8e-24 84.1 4.7 1e-23 83.9 4.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.21 OAG15280.1 - 0.045 13.7 0.2 0.045 13.7 0.2 3.2 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DUF4094 PF13334.6 OAG15281.1 - 0.077 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) NmrA PF05368.13 OAG15282.1 - 1.8e-15 57.2 0.0 2.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG15282.1 - 2.1e-10 40.8 0.0 5.2e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG15282.1 - 6.1e-06 25.9 0.2 3.3e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG15283.1 - 2e-67 228.0 0.0 2.5e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIM24 PF01987.17 OAG15284.1 - 0.0024 17.7 0.1 0.66 9.7 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial biogenesis AIM24 Kelch_3 PF13415.6 OAG15284.1 - 0.11 12.8 3.9 0.17 12.2 0.1 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain adh_short PF00106.25 OAG15285.1 - 6e-37 127.0 0.3 7.8e-37 126.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15285.1 - 1.4e-26 93.5 0.1 2.4e-26 92.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15285.1 - 1.3e-17 64.3 0.1 1.6e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG15285.1 - 4e-09 36.0 0.1 5e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG15285.1 - 2.4e-07 30.5 0.2 6.3e-07 29.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG15285.1 - 0.0014 18.7 0.2 0.0032 17.5 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 OAG15285.1 - 0.0045 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ThiF PF00899.21 OAG15285.1 - 0.033 13.5 0.3 0.071 12.4 0.3 1.5 1 0 0 1 1 1 0 ThiF family Peptidase_S3 PF00944.19 OAG15285.1 - 0.052 13.3 0.1 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Alphavirus core protein DUF3176 PF11374.8 OAG15286.1 - 3.5e-28 97.9 0.9 9.4e-28 96.5 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) UBM PF14377.6 OAG15287.1 - 0.00048 19.5 0.4 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin binding region Senescence PF06911.12 OAG15288.1 - 1.2e-53 182.2 11.8 1.8e-53 181.6 11.8 1.3 1 0 0 1 1 1 1 Senescence-associated protein DIOX_N PF14226.6 OAG15290.1 - 1.1e-27 97.1 0.0 5.5e-26 91.6 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG15290.1 - 1.4e-12 48.0 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3283 PF11686.8 OAG15290.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) bZIP_1 PF00170.21 OAG15291.1 - 0.00023 21.2 10.6 0.0029 17.7 10.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 OAG15291.1 - 0.00078 20.0 0.1 0.0017 18.9 0.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA TSC22 PF01166.18 OAG15291.1 - 0.0051 17.1 2.5 0.018 15.4 0.4 2.2 1 1 1 2 2 2 1 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 OAG15291.1 - 0.12 12.6 2.9 0.22 11.8 2.9 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 OAG15291.1 - 0.17 12.0 11.9 2.2 8.4 4.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HAUS6_N PF14661.6 OAG15291.1 - 0.29 10.7 3.9 0.43 10.1 3.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_1 PF00232.18 OAG15292.1 - 1.1e-155 518.6 0.0 1.3e-155 518.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1479 PF07350.12 OAG15293.1 - 7.1e-168 558.7 0.0 8.2e-168 558.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 OAG15293.1 - 0.047 13.9 0.2 4.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3347 PF11827.8 OAG15293.1 - 0.069 13.3 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF5337 PF17272.2 OAG15295.1 - 0.14 12.0 0.5 0.27 11.1 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) WD40 PF00400.32 OAG15296.1 - 2.1e-35 120.2 6.4 3.6e-07 30.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15296.1 - 2.3e-13 50.3 0.0 8.8e-05 22.7 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAG15296.1 - 0.11 10.8 0.0 0.33 9.2 0.0 1.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TRAPP PF04051.16 OAG15297.1 - 2.3e-35 121.4 0.0 2.8e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MIP PF00230.20 OAG15300.1 - 4.3e-48 164.0 15.1 5.7e-48 163.6 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein IATP PF04568.12 OAG15301.1 - 3.4e-21 75.5 0.9 4.1e-21 75.2 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 14-3-3 PF00244.20 OAG15302.1 - 2.5e-106 354.1 5.5 2.9e-106 354.0 5.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OAG15302.1 - 0.023 15.0 1.2 2.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TerB PF05099.13 OAG15302.1 - 0.026 14.5 1.2 0.041 13.8 0.3 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB Orbi_VP5 PF00901.17 OAG15302.1 - 0.17 10.2 3.8 0.29 9.5 3.8 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TPR_19 PF14559.6 OAG15302.1 - 1.1 9.9 5.3 0.42 11.1 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 OAG15303.1 - 5.9e-57 191.8 0.6 1.2e-56 190.8 0.2 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG15303.1 - 8.7e-37 126.9 0.0 7.7e-36 123.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain SecIII_SopE_N PF05364.14 OAG15303.1 - 0.19 11.8 0.7 4.3 7.5 0.2 2.5 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus CybS PF05328.12 OAG15304.1 - 1.3e-51 173.8 0.0 2e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF3292 PF11696.8 OAG15305.1 - 2.1e-06 26.5 17.6 0.00069 18.1 0.9 3.7 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) MFS_4 PF06779.14 OAG15305.1 - 0.15 11.3 0.5 0.29 10.4 0.4 1.5 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF639 PF04842.12 OAG15305.1 - 0.18 11.2 4.5 5 6.5 0.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF639) CoxIIa PF08113.11 OAG15305.1 - 1.5 8.7 5.6 3.5 7.5 3.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family AA_permease_2 PF13520.6 OAG15306.1 - 4.8e-48 164.0 48.3 5.8e-48 163.8 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG15306.1 - 6.5e-24 84.4 44.6 3.8e-23 81.8 44.5 1.8 1 1 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 OAG15306.1 - 0.31 11.1 5.6 0.51 10.4 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) LPG_synthase_TM PF03706.13 OAG15306.1 - 1.2 8.6 30.5 0.062 12.8 2.7 3.5 3 1 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region GFA PF04828.14 OAG15307.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 OAG15307.1 - 0.085 12.6 0.3 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain FMO-like PF00743.19 OAG15308.1 - 4.7e-55 187.0 0.0 6.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG15308.1 - 1.2e-19 70.7 0.0 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG15308.1 - 2.8e-14 53.0 0.0 9e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG15308.1 - 1.8e-06 28.0 0.1 0.22 11.5 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG15308.1 - 3.3e-06 26.5 0.1 5.1e-05 22.6 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG15308.1 - 0.00072 19.7 0.0 0.0051 17.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG15308.1 - 0.024 13.3 0.0 0.97 8.1 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAG15308.1 - 0.041 13.3 0.1 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAG15308.1 - 0.063 12.9 0.0 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AtuA PF07287.11 OAG15310.1 - 1.4e-134 448.2 0.9 1.8e-134 447.9 0.9 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF1048 PF06304.11 OAG15310.1 - 0.014 15.8 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) Methyltransf_23 PF13489.6 OAG15312.1 - 6.8e-21 74.8 0.0 9.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15312.1 - 9.2e-09 35.9 0.0 2.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15312.1 - 6.8e-07 29.8 0.0 2.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15312.1 - 2.6e-05 24.0 0.0 0.00028 20.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG15312.1 - 5.4e-05 23.9 0.0 0.00037 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG15312.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 OAG15312.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAG15312.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAG15312.1 - 0.054 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG15312.1 - 0.23 10.8 0.0 0.64 9.3 0.0 1.7 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family SBF PF01758.16 OAG15313.1 - 9.5e-53 178.8 6.5 1.9e-52 177.8 6.5 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family PIG-P PF08510.12 OAG15313.1 - 0.31 11.0 5.8 4.1 7.4 0.2 3.1 2 1 0 2 2 2 0 PIG-P HLH PF00010.26 OAG15315.1 - 1.4e-13 50.6 0.1 1.4e-13 50.6 0.1 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain K-box PF01486.17 OAG15315.1 - 0.21 11.8 3.7 7.5 6.8 0.0 2.7 3 0 0 3 3 3 0 K-box region CDC45 PF02724.14 OAG15315.1 - 2.6 6.2 9.4 3.5 5.8 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein bZIP_2 PF07716.15 OAG15315.1 - 3.8 7.7 12.6 0.051 13.7 2.1 2.7 3 0 0 3 3 3 0 Basic region leucine zipper zf-RING_2 PF13639.6 OAG15316.1 - 3.4e-12 46.5 6.1 5.9e-12 45.7 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG15316.1 - 5.4e-09 35.6 3.1 1.4e-08 34.3 3.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAG15316.1 - 1.7e-08 34.2 2.7 3e-08 33.4 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG15316.1 - 4.7e-08 32.7 3.8 7.4e-08 32.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG15316.1 - 2.8e-07 30.7 6.6 8.1e-07 29.2 6.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG15316.1 - 1.4e-06 28.2 0.6 5.5e-06 26.3 0.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG15316.1 - 9.2e-06 25.5 3.7 1.6e-05 24.8 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain SKG6 PF08693.10 OAG15316.1 - 4.3e-05 22.8 2.4 4.3e-05 22.8 2.4 1.6 2 0 0 2 2 1 1 Transmembrane alpha-helix domain zf-ANAPC11 PF12861.7 OAG15316.1 - 5.2e-05 23.2 1.8 8.7e-05 22.5 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAG15316.1 - 0.00015 21.6 2.8 0.00015 21.6 2.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAG15316.1 - 0.017 15.2 1.9 0.017 15.2 1.9 2.0 2 1 0 2 2 1 0 RING-variant domain FANCL_C PF11793.8 OAG15316.1 - 0.018 15.2 9.1 0.16 12.1 6.9 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OAG15316.1 - 0.018 14.9 7.2 0.034 14.0 5.7 2.1 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 DUF3377 PF11857.8 OAG15316.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4448 PF14610.6 OAG15316.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zn_ribbon_17 PF17120.5 OAG15316.1 - 0.045 13.4 5.0 0.086 12.5 5.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 OAG15316.1 - 0.17 12.0 1.9 0.32 11.1 1.9 1.5 1 1 0 1 1 1 0 KIAA1045 RING finger TMEM154 PF15102.6 OAG15316.1 - 0.21 11.5 3.7 0.67 9.9 3.7 1.9 1 1 0 1 1 1 0 TMEM154 protein family zf-RING-like PF08746.11 OAG15316.1 - 0.29 11.5 4.1 0.57 10.5 4.1 1.6 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OAG15316.1 - 0.3 11.3 3.9 0.64 10.2 3.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 OAG15316.1 - 0.65 9.9 5.4 1.5 8.7 5.4 1.7 1 1 0 1 1 1 0 PHD-finger HET PF06985.11 OAG15317.1 - 5.9e-27 94.8 0.0 1.1e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_Rpb2_6 PF00562.28 OAG15318.1 - 5.1e-123 411.0 0.1 8e-123 410.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG15318.1 - 2.4e-60 203.5 0.0 8.3e-60 201.8 0.0 1.9 2 1 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAG15318.1 - 9.6e-42 142.8 0.1 2.4e-41 141.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAG15318.1 - 4.2e-32 110.4 0.0 8.4e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAG15318.1 - 1.3e-25 89.3 0.1 3.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OAG15318.1 - 5.9e-22 77.7 0.3 1.3e-21 76.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OAG15318.1 - 9.3e-21 74.2 0.2 2.9e-20 72.6 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.26 OAG15319.1 - 3.3e-30 104.7 0.2 5.5e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG15319.1 - 6.1e-10 40.3 0.0 9.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG15319.1 - 0.00014 21.7 0.0 0.0005 19.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG15319.1 - 0.0076 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG15319.1 - 0.039 13.3 0.3 0.059 12.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ubiquitin PF00240.23 OAG15320.1 - 3e-18 65.3 0.0 5.3e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAG15320.1 - 2e-08 34.0 0.1 5.8e-08 32.5 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 OAG15320.1 - 1.7e-05 25.3 0.1 3.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 OAG15320.1 - 1.8e-05 24.5 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAG15320.1 - 0.00028 21.0 0.1 0.00047 20.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 OAG15320.1 - 0.0054 16.6 29.3 0.37 10.8 6.4 3.9 3 1 0 3 3 3 3 STI1 domain HOIP-UBA PF16678.5 OAG15320.1 - 0.013 15.5 0.2 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair PadR PF03551.14 OAG15322.1 - 0.045 13.7 0.1 1.2 9.2 0.0 3.0 2 2 2 4 4 4 0 Transcriptional regulator PadR-like family HET PF06985.11 OAG15323.1 - 1.1e-37 129.6 0.8 2.3e-37 128.6 0.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG15324.1 - 1.9e-36 125.6 1.3 3.3e-36 124.8 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG15325.1 - 1.4e-24 87.1 0.0 3.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CTNNBL PF08216.11 OAG15326.1 - 1.1e-38 131.5 0.3 3.5e-38 129.9 0.3 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear SIL1 PF16782.5 OAG15326.1 - 0.0033 16.7 0.0 0.28 10.3 0.0 2.5 1 1 0 2 2 2 2 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 OAG15326.1 - 0.013 15.9 0.4 0.05 14.0 0.1 2.2 2 0 0 2 2 2 0 HEAT repeats Mo25 PF08569.11 OAG15326.1 - 0.052 12.9 0.6 0.087 12.2 0.2 1.7 2 1 0 2 2 2 0 Mo25-like Dus PF01207.17 OAG15327.1 - 7.7e-40 136.9 0.0 1.5e-26 93.2 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 OAG15327.1 - 1.4e-05 24.7 9.4 0.0026 17.5 0.4 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG15327.1 - 6.1e-05 22.9 8.2 0.063 13.4 1.5 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OAG15327.1 - 0.00043 20.1 6.8 0.027 14.4 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SIS_2 PF13580.6 OAG15327.1 - 0.018 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 SIS domain Torus PF16131.5 OAG15327.1 - 4.3 8.1 7.9 15 6.4 0.7 2.7 1 1 1 2 2 2 0 Torus domain Bap31 PF05529.12 OAG15328.1 - 1.9e-50 170.2 3.3 2.7e-50 169.7 3.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAG15328.1 - 2.2e-11 43.6 1.2 2.2e-11 43.6 1.2 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Lebercilin PF15619.6 OAG15328.1 - 0.0014 18.3 0.3 0.0018 17.9 0.3 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 OAG15328.1 - 0.0086 15.8 1.4 0.16 11.7 0.1 3.0 3 0 0 3 3 3 1 Septum formation initiator She9_MDM33 PF05546.11 OAG15328.1 - 0.0093 15.8 0.2 0.0093 15.8 0.2 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family Nup54_57_C PF18570.1 OAG15328.1 - 0.033 13.8 1.0 0.91 9.2 0.1 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain TolA_bind_tri PF16331.5 OAG15328.1 - 0.055 13.5 1.1 0.4 10.8 0.2 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Csm1_N PF18504.1 OAG15328.1 - 0.11 12.9 1.8 0.13 12.6 0.8 1.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Trimer_CC PF08954.11 OAG15328.1 - 0.23 11.1 0.9 6.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Trimerisation motif Amidase PF01425.21 OAG15329.1 - 8.5e-67 226.1 0.0 1.1e-65 222.4 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF2205 PF10224.9 OAG15330.1 - 6.5e-34 115.8 0.6 1.5e-33 114.6 0.6 1.6 1 0 0 1 1 1 1 Short coiled-coil protein His_Phos_2 PF00328.22 OAG15331.1 - 2.5e-37 129.1 0.0 3.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) kleA_kleC PF17383.2 OAG15332.1 - 0.069 13.5 0.3 0.14 12.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A ADH_N PF08240.12 OAG15333.1 - 4.9e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NPCBM_assoc PF10633.9 OAG15333.1 - 0.98 9.7 4.1 13 6.1 0.1 3.1 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FA PF08736.11 OAG15334.1 - 0.43 10.7 3.4 14 5.9 0.3 2.6 2 0 0 2 2 2 0 FERM adjacent (FA) MFS_1 PF07690.16 OAG15335.1 - 3.7e-58 197.2 46.4 2.2e-43 148.5 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG15335.1 - 5e-10 38.5 20.0 2.2e-06 26.5 7.1 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAG15335.1 - 3e-06 26.3 11.1 0.0021 17.0 7.2 3.2 2 2 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 OAG15335.1 - 0.00034 20.0 20.2 0.0063 15.9 8.6 2.5 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG15335.1 - 0.01 14.1 0.7 0.17 10.2 1.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cellulase PF00150.18 OAG15336.1 - 1.2e-17 64.2 5.9 1.1e-16 61.2 5.9 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 OAG15337.1 - 6.6e-38 130.5 27.0 6.6e-38 130.5 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Clr2_transil PF16761.5 OAG15339.1 - 2.6e-18 66.6 0.1 6.4e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAG15339.1 - 4.8e-15 56.6 1.7 6.8e-14 52.9 0.0 3.1 3 1 0 3 3 3 1 Transcription-silencing protein Clr2 UPF0524 PF15823.5 OAG15339.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 Nucleo_P87 PF07267.11 OAG15339.1 - 0.57 9.0 3.4 0.92 8.3 3.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CorA PF01544.18 OAG15340.1 - 4.7e-05 22.9 0.0 0.00014 21.3 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1270 PF06900.11 OAG15340.1 - 0.061 13.7 0.6 0.35 11.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DNA_pol_phi PF04931.13 OAG15340.1 - 0.13 10.3 26.1 0.22 9.6 26.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Rhabdo_ncap PF00945.18 OAG15340.1 - 0.24 10.2 5.9 0.4 9.5 5.9 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop14 PF04147.12 OAG15340.1 - 0.45 8.7 20.5 0.68 8.1 20.5 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 OAG15340.1 - 0.77 7.8 12.0 1.3 7.0 12.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.8 OAG15340.1 - 0.97 9.6 25.2 2.2 8.5 25.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 OAG15340.1 - 1.2 7.3 16.6 2.1 6.5 16.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 OAG15340.1 - 1.4 8.8 5.0 3 7.7 5.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.12 OAG15340.1 - 1.7 7.9 22.9 2.8 7.2 22.9 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OAG15340.1 - 1.9 7.8 21.9 3.2 7.1 21.9 1.3 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OAG15340.1 - 1.9 8.0 21.8 3.5 7.2 21.8 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 OAG15340.1 - 2.3 7.9 24.0 0.28 10.9 19.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 OAG15340.1 - 2.7 7.9 15.8 6 6.8 15.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.10 OAG15340.1 - 3 8.2 6.4 6 7.1 6.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.9 OAG15340.1 - 3.2 6.8 26.7 5.7 6.0 26.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 OAG15340.1 - 5 7.1 12.1 13 5.8 12.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal TFB6 PF17110.5 OAG15340.1 - 5.4 6.7 9.5 14 5.3 9.4 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FYDLN_acid PF09538.10 OAG15340.1 - 6.2 7.6 20.5 19 6.0 20.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CFEM PF05730.11 OAG15341.1 - 1.7e-11 44.0 7.6 2.9e-11 43.3 7.6 1.4 1 0 0 1 1 1 1 CFEM domain Thioredoxin_3 PF13192.6 OAG15344.1 - 0.11 12.5 0.7 0.22 11.6 0.7 1.5 1 0 0 1 1 1 0 Thioredoxin domain FPN1 PF06963.12 OAG15346.1 - 1e-124 416.5 17.0 1.2e-124 416.3 17.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF2759 PF10958.8 OAG15346.1 - 0.068 12.9 2.0 0.2 11.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) F-box-like_2 PF13013.6 OAG15347.1 - 0.095 12.7 0.1 20 5.2 0.0 2.5 2 0 0 2 2 2 0 F-box-like domain HET PF06985.11 OAG15348.1 - 2.8e-26 92.6 0.3 2.8e-26 92.6 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAG15349.1 - 2e-08 34.8 0.1 8.3e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Nnf1 PF03980.14 OAG15349.1 - 0.095 13.1 0.2 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Nnf1 APH PF01636.23 OAG15350.1 - 1.3e-11 45.0 0.1 1.3e-10 41.6 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1929 PF09118.11 OAG15351.1 - 1e-19 70.6 0.0 2.6e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_1 PF01344.25 OAG15351.1 - 5e-14 51.6 0.4 0.00015 21.2 0.1 4.4 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 OAG15351.1 - 3.9e-13 49.2 8.0 0.00011 22.4 0.0 5.3 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OAG15351.1 - 4e-08 33.1 6.7 0.09 12.8 0.0 5.4 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG15351.1 - 7.1e-08 32.1 0.6 0.049 13.6 0.3 5.0 4 1 0 4 4 4 2 Kelch motif Glyoxal_oxid_N PF07250.11 OAG15351.1 - 5.5e-07 29.0 0.0 0.01 15.0 0.0 2.7 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF4018 PF13210.6 OAG15351.1 - 0.045 13.5 0.2 0.067 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) DUF1668 PF07893.13 OAG15351.1 - 0.12 11.7 0.0 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) DUF5122 PF17164.4 OAG15351.1 - 1.3 9.4 4.4 3.7 7.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller zinc_ribbon_5 PF13719.6 OAG15352.1 - 0.0025 17.5 4.3 0.021 14.6 4.3 2.2 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 OAG15352.1 - 0.0049 16.8 3.5 0.2 11.6 3.5 2.2 1 1 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAG15352.1 - 0.04 14.1 1.8 3.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 OAG15352.1 - 0.23 10.9 4.4 2 7.9 4.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-LSD1 PF06943.12 OAG15352.1 - 1.7 8.6 5.3 7.3 6.5 1.7 2.2 2 0 0 2 2 2 0 LSD1 zinc finger PADR1 PF08063.12 OAG15352.1 - 2.9 7.8 5.8 1.5 8.7 0.3 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain BaffR-Tall_bind PF09256.10 OAG15353.1 - 0.19 11.5 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding HPP PF04982.13 OAG15354.1 - 4.2e-39 133.5 8.4 1e-38 132.2 6.3 1.9 2 0 0 2 2 2 1 HPP family Tmemb_14 PF03647.13 OAG15354.1 - 0.0016 19.2 3.9 0.044 14.5 2.0 2.5 2 1 0 2 2 2 1 Transmembrane proteins 14C F-box-like PF12937.7 OAG15355.1 - 1.7e-12 47.0 0.6 3.3e-12 46.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG15355.1 - 1.5e-08 34.3 0.8 3.3e-08 33.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain SKG6 PF08693.10 OAG15356.1 - 0.0016 17.8 0.9 0.0046 16.3 0.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OAG15356.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CcmD PF04995.14 OAG15356.1 - 0.1 12.7 1.3 0.24 11.5 1.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Insulin_TMD PF17870.1 OAG15356.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vps62 PF06101.11 OAG15359.1 - 1.5e-16 59.9 0.0 2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Toxin_10 PF05431.11 OAG15359.1 - 1.2e-07 31.3 0.5 2e-07 30.6 0.5 1.3 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 ETX_MTX2 PF03318.13 OAG15359.1 - 0.0021 17.8 9.9 0.0042 16.9 7.0 2.1 2 0 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 HET PF06985.11 OAG15360.1 - 3.9e-27 95.4 4.4 5.5e-24 85.2 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SBDS PF01172.18 OAG15361.1 - 7.4e-20 70.8 0.2 8.6e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 OAG15362.1 - 7.8e-29 101.2 0.1 1.4e-28 100.3 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OAG15362.1 - 0.022 15.3 0.0 0.075 13.6 0.0 1.9 1 0 0 1 1 1 0 PH domain Nas2_N PF18265.1 OAG15363.1 - 5.7e-31 106.3 0.1 8.3e-31 105.8 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAG15363.1 - 4.1e-10 39.3 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAG15363.1 - 1.1e-05 25.6 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAG15363.1 - 1.8e-05 25.0 0.0 3.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAG15363.1 - 0.0015 18.9 0.2 0.022 15.1 0.2 2.2 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain ABC_tran_CTD PF16326.5 OAG15363.1 - 0.015 15.5 2.1 3.5 7.9 0.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4806 PF16064.5 OAG15363.1 - 0.21 11.9 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Ras PF00071.22 OAG15364.1 - 2.3e-48 163.9 0.0 2.8e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG15364.1 - 2e-28 99.0 0.0 4.7e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG15364.1 - 9.5e-10 38.2 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OAG15364.1 - 0.00095 19.5 0.1 0.006 17.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 OAG15364.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG15364.1 - 0.0053 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 OAG15364.1 - 0.023 14.2 0.2 0.045 13.2 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 OAG15364.1 - 0.027 13.6 1.7 1.4 8.0 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 OAG15364.1 - 0.038 13.5 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OAG15364.1 - 0.059 13.4 0.1 0.13 12.2 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OAG15364.1 - 0.073 12.8 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG15364.1 - 0.093 12.9 1.1 0.23 11.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG15364.1 - 0.096 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArgoMid PF16487.5 OAG15364.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute RsgA_GTPase PF03193.16 OAG15364.1 - 0.16 11.9 0.2 9.5 6.1 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Zn_clus PF00172.18 OAG15365.1 - 3.4e-08 33.5 9.1 5.9e-08 32.7 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG15365.1 - 6.3e-08 32.0 0.1 1.1e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 OAG15366.1 - 1.5e-34 119.6 0.0 1.5e-32 113.0 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG15366.1 - 2.6e-33 115.8 0.0 2.5e-24 86.3 0.0 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG15366.1 - 2.3e-05 23.7 0.0 0.0038 16.4 0.0 2.8 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG15366.1 - 2.4e-05 23.5 0.0 0.16 10.9 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG15366.1 - 4.6e-05 22.7 0.0 0.00089 18.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OAG15366.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 OAG15366.1 - 0.014 15.3 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 KR domain NAD_binding_2 PF03446.15 OAG15366.1 - 0.21 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_114 PF03537.13 OAG15367.1 - 1.2e-81 273.5 0.0 1.4e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.21 OAG15368.1 - 0.044 13.7 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Glyco_trans_1_4 PF13692.6 OAG15369.1 - 2.4e-10 41.0 0.0 4.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAG15369.1 - 9e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 OAG15369.1 - 6.3e-05 22.8 0.0 0.002 17.9 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3492) Orthopox_35kD PF02250.15 OAG15369.1 - 0.13 12.0 0.0 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 35kD major secreted virus protein Pectate_lyase PF03211.13 OAG15370.1 - 1.7e-74 249.7 5.0 2.4e-74 249.3 5.0 1.2 1 0 0 1 1 1 1 Pectate lyase Utp11 PF03998.13 OAG15371.1 - 2.9e-65 220.6 34.9 5.2e-65 219.8 34.9 1.4 1 1 0 1 1 1 1 Utp11 protein Alpha_kinase PF02816.18 OAG15371.1 - 0.086 13.0 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Alpha-kinase family DUF2250 PF10007.9 OAG15371.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) adh_short PF00106.25 OAG15372.1 - 1.5e-39 135.5 0.5 1.7e-39 135.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15372.1 - 1.8e-33 116.0 0.5 2.3e-33 115.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15372.1 - 2.1e-10 40.8 4.2 7e-10 39.1 3.4 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_8 PF13450.6 OAG15372.1 - 0.036 14.3 1.0 0.12 12.6 0.2 2.1 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.6 OAG15372.1 - 0.1 12.5 1.0 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Cmc1 PF08583.10 OAG15373.1 - 7.6e-14 51.5 4.5 1.3e-13 50.7 4.5 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 OAG15373.1 - 0.0068 16.4 0.8 0.015 15.3 0.8 1.6 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 OAG15373.1 - 0.038 14.3 0.9 3.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) TFIID-31kDa PF02291.15 OAG15374.1 - 1.2e-42 144.8 0.0 1.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Spt20 PF12090.8 OAG15374.1 - 0.06 13.0 6.1 0.083 12.5 6.1 1.2 1 0 0 1 1 1 0 Spt20 family Mucin PF01456.17 OAG15374.1 - 0.25 11.3 8.3 0.5 10.4 8.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4106 PF13388.6 OAG15374.1 - 3.8 6.6 8.3 4.6 6.4 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Retinal PF15449.6 OAG15374.1 - 4.2 5.0 10.2 5 4.8 10.2 1.1 1 0 0 1 1 1 0 Retinal protein LNS2 PF08235.13 OAG15375.1 - 2e-94 315.3 0.0 2.9e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAG15375.1 - 1e-41 141.0 0.0 2.3e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAG15375.1 - 0.0036 16.9 0.4 0.077 12.6 0.0 2.7 3 1 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 OAG15376.1 - 5.6e-07 29.8 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain HSBP1 PF06825.12 OAG15376.1 - 0.52 10.2 2.9 1.2 9.0 2.9 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Glyco_hydro_43 PF04616.14 OAG15377.1 - 1.6e-13 50.6 1.2 2.1e-13 50.2 0.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 NmrA PF05368.13 OAG15378.1 - 2.9e-12 46.7 0.0 6.3e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG15378.1 - 4.5e-09 36.5 0.0 6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG15378.1 - 0.002 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OAG15378.1 - 0.0056 16.8 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF1400 PF07176.11 OAG15378.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) TrkA_N PF02254.18 OAG15378.1 - 0.082 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain THF_DHG_CYH_C PF02882.19 OAG15378.1 - 0.13 11.6 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG15378.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 OAG15379.1 - 7.9e-28 97.7 0.0 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 OAG15379.1 - 0.0033 17.9 0.2 0.12 12.9 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG15379.1 - 0.057 12.7 0.1 0.26 10.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG15379.1 - 0.088 12.0 0.1 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG15379.1 - 0.092 11.8 0.0 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 OAG15379.1 - 0.12 12.6 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.12 OAG15381.1 - 2.2e-29 101.5 1.2 2.2e-29 101.5 1.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15381.1 - 1.3e-16 60.7 1.0 4.3e-16 59.1 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG15381.1 - 3.4e-07 30.0 0.1 3e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG15381.1 - 1.6e-05 24.3 0.2 3.2e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG15381.1 - 0.00021 22.3 0.0 0.00061 20.8 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG15381.1 - 0.00033 20.0 0.1 0.001 18.4 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG15381.1 - 0.0027 17.6 0.1 0.0041 17.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG15381.1 - 0.004 17.7 0.1 0.048 14.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG15381.1 - 0.0086 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG15381.1 - 0.0087 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 OAG15381.1 - 0.053 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_25 PF13649.6 OAG15381.1 - 0.079 13.7 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.6 OAG15381.1 - 0.1 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG15381.1 - 0.12 11.0 0.2 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 OAG15381.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 OAG15383.1 - 1.3e-05 24.7 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Host_attach PF10116.9 OAG15383.1 - 0.012 16.2 0.5 4.5 7.9 0.2 2.5 2 0 0 2 2 2 0 Protein required for attachment to host cells Pkinase_Tyr PF07714.17 OAG15383.1 - 0.036 13.3 0.0 0.25 10.6 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 OAG15384.1 - 1.7e-24 86.2 0.3 3.6e-12 46.7 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG15384.1 - 7.3e-17 61.5 0.0 2.2e-06 28.1 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG15384.1 - 1e-15 56.2 0.1 0.00054 20.2 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OAG15384.1 - 1.6e-13 50.4 2.1 0.0011 19.3 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG15384.1 - 2.3e-12 46.9 1.5 1.3e-05 25.3 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 OAG15384.1 - 5.2e-09 35.8 1.0 5.5e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15384.1 - 2.3e-05 23.8 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.28 OAG15386.1 - 5e-93 312.0 0.0 6.1e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG15386.1 - 1.8e-13 51.2 0.1 5.6e-13 49.7 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 OAG15387.1 - 2.2e-37 128.4 0.0 3.3e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15387.1 - 1.7e-31 109.6 0.0 2.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAG15387.1 - 0.00013 21.9 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAG15387.1 - 0.00031 20.7 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 OAG15387.1 - 0.011 15.4 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAG15387.1 - 0.04 14.5 0.1 0.095 13.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG15387.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 OAG15388.1 - 2.4e-41 141.2 0.1 6.1e-14 52.6 0.0 5.6 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 OAG15388.1 - 2.4e-38 131.8 0.0 1.9e-37 128.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG15388.1 - 1.4e-26 93.9 38.9 1.1e-23 84.4 0.0 6.8 7 0 0 7 7 7 2 AAA domain AAA_30 PF13604.6 OAG15388.1 - 5.3e-20 71.9 13.3 1.6e-06 28.0 0.1 6.0 6 0 0 6 6 5 5 AAA domain AAA_19 PF13245.6 OAG15388.1 - 1.3e-19 71.0 1.7 4.5e-10 40.0 0.0 6.1 4 2 1 5 5 5 4 AAA domain AAA_5 PF07728.14 OAG15388.1 - 2.6e-15 56.6 1.8 0.0032 17.4 0.0 5.8 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_6 PF17866.1 OAG15388.1 - 1.3e-14 54.1 13.5 3.1e-06 27.3 0.1 4.4 4 0 0 4 4 3 2 AAA lid domain Mg_chelatase PF01078.21 OAG15388.1 - 2.5e-11 43.4 0.3 0.14 11.6 0.0 5.3 5 0 0 5 5 5 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OAG15388.1 - 6.7e-10 39.4 12.9 0.056 13.7 0.2 7.1 5 3 1 6 6 5 3 AAA domain RuvB_N PF05496.12 OAG15388.1 - 8.6e-09 35.3 0.1 0.036 13.8 0.0 4.6 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OAG15388.1 - 9.2e-09 35.5 1.5 0.00086 19.3 0.0 4.9 4 1 1 5 5 4 2 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 OAG15388.1 - 4.6e-08 33.4 0.2 1.9 8.9 0.0 5.1 4 0 0 4 4 4 1 RNA helicase AAA_24 PF13479.6 OAG15388.1 - 8.1e-08 32.2 2.1 0.76 9.5 0.0 5.3 5 0 0 5 5 5 3 AAA domain AAA_33 PF13671.6 OAG15388.1 - 2.5e-06 27.7 7.0 2.3 8.4 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 OAG15388.1 - 3.1e-06 27.8 9.0 1.6 9.3 0.0 5.7 5 0 0 5 5 5 1 AAA domain AAA_7 PF12775.7 OAG15388.1 - 1.4e-05 24.7 0.2 12 5.4 0.0 4.4 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAG15388.1 - 3e-05 24.5 15.4 2.1 8.7 0.0 6.0 6 1 0 6 6 4 3 AAA ATPase domain Sigma54_activ_2 PF14532.6 OAG15388.1 - 3e-05 24.1 0.6 0.033 14.3 0.0 4.2 4 0 0 4 4 4 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 OAG15388.1 - 3.6e-05 23.6 2.0 6.5 6.4 0.0 5.1 5 0 0 5 5 5 0 IstB-like ATP binding protein SRP54 PF00448.22 OAG15388.1 - 0.0003 20.5 2.6 0.18 11.4 0.0 4.0 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 OAG15388.1 - 0.0013 18.3 5.8 2.7 7.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain PhoH PF02562.16 OAG15388.1 - 0.0014 18.1 2.8 0.97 8.8 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein DUF2075 PF09848.9 OAG15388.1 - 0.002 17.5 0.0 0.002 17.5 0.0 5.5 6 2 0 6 6 4 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 OAG15388.1 - 0.0048 16.8 0.0 2.4 8.0 0.0 3.5 4 0 0 4 4 3 1 Rad17 P-loop domain UvrD-helicase PF00580.21 OAG15388.1 - 0.0091 15.6 0.0 0.0091 15.6 0.0 5.2 6 0 0 6 6 4 1 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 OAG15388.1 - 0.014 15.1 1.0 80 3.1 0.1 4.4 4 0 0 4 4 4 0 P-loop containing region of AAA domain CbiA PF01656.23 OAG15388.1 - 0.092 12.8 3.4 7.1 6.7 0.1 4.5 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 OAG15388.1 - 0.12 12.3 2.9 60 3.5 0.0 4.2 4 0 0 4 4 4 0 NTPase Helicase_RecD PF05127.14 OAG15388.1 - 0.88 9.4 5.2 0.94 9.3 0.0 3.4 3 0 0 3 3 2 0 Helicase ABC_tran PF00005.27 OAG15388.1 - 0.89 10.1 12.6 8.9 6.8 0.0 5.0 5 0 0 5 5 4 0 ABC transporter ATPase PF06745.13 OAG15388.1 - 3.4 6.9 14.0 2.3 7.5 0.0 5.3 6 0 0 6 6 5 0 KaiC HET PF06985.11 OAG15390.1 - 3.7e-25 89.0 0.0 7.4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TauD PF02668.16 OAG15391.1 - 4.4e-17 62.8 0.1 5e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG15392.1 - 5.2e-30 104.6 48.0 5.2e-30 104.6 48.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15392.1 - 7.5e-05 21.8 38.8 0.0065 15.4 16.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter ADC PF06314.11 OAG15394.1 - 0.0037 16.9 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) zf-C2H2_aberr PF17017.5 OAG15395.1 - 0.00016 21.8 2.7 0.07 13.3 0.2 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG15395.1 - 0.00036 20.8 13.2 0.04 14.4 1.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG15395.1 - 0.00059 20.5 12.6 0.037 14.9 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG15395.1 - 0.027 14.9 0.5 0.027 14.9 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG15395.1 - 0.78 10.1 6.1 2.1 8.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAG15395.1 - 2.8 8.3 6.4 2.7 8.4 0.3 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) HET PF06985.11 OAG15396.1 - 8.5e-29 100.8 3.2 3.7e-27 95.5 3.2 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG15397.1 - 8.8e-14 51.4 0.0 2.1e-12 46.9 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15397.1 - 7.9e-08 32.1 0.1 1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAG15397.1 - 0.0001 21.6 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG15397.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG15398.1 - 3.7e-09 36.3 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15398.1 - 0.00048 19.8 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.27 OAG15399.1 - 2.3e-06 27.8 3.0 4.9e-06 26.7 2.4 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG15399.1 - 0.0014 18.2 0.1 0.0029 17.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF521 PF04412.13 OAG15400.1 - 2e-121 405.5 0.0 2.7e-121 405.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 OAG15400.1 - 2.5e-29 100.9 0.1 8.4e-29 99.2 0.0 1.9 2 0 0 2 2 2 1 Aconitase X swivel domain Acetyltransf_3 PF13302.7 OAG15401.1 - 9.9e-22 78.1 0.0 1.2e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG15401.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Fib_alpha PF08702.10 OAG15402.1 - 0.007 16.6 2.9 0.007 16.6 2.9 3.4 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family GAS PF13851.6 OAG15402.1 - 0.33 10.3 26.9 0.02 14.2 13.4 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 OAG15402.1 - 1.5 8.7 12.0 0.35 10.7 3.0 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Goodbye PF17109.5 OAG15402.1 - 2.7 8.5 6.3 13 6.3 0.8 2.9 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain FapA PF03961.13 OAG15402.1 - 2.7 6.5 11.7 0.77 8.3 6.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Mod_r PF07200.13 OAG15402.1 - 4.9 7.3 24.2 0.29 11.2 14.7 2.9 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PH_4 PF15404.6 OAG15402.1 - 9.5 6.0 7.4 0.36 10.6 1.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_23 PF13489.6 OAG15404.1 - 2.6e-09 37.1 0.0 3.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15404.1 - 2.8e-06 28.0 0.0 9e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15404.1 - 0.00025 20.9 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15404.1 - 0.00056 20.5 0.0 0.0017 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cu-oxidase_2 PF07731.14 OAG15405.1 - 5.2e-41 139.6 10.9 1.6e-40 138.0 1.0 3.6 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG15405.1 - 4.6e-38 129.9 2.3 4.6e-38 129.9 2.3 2.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG15405.1 - 5e-34 117.7 1.7 1.5e-30 106.5 0.5 2.7 2 0 0 2 2 2 2 Multicopper oxidase ERbeta_N PF12497.8 OAG15406.1 - 0.083 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Estrogen receptor beta Sugar_tr PF00083.24 OAG15408.1 - 2.9e-86 290.1 25.0 3.3e-86 290.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15408.1 - 3.4e-34 118.3 47.8 1.3e-26 93.4 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG15408.1 - 3e-10 39.2 1.4 3e-10 39.2 1.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DNase_NucA_NucB PF14040.6 OAG15409.1 - 5.7e-08 33.1 1.0 1.4e-07 31.8 1.0 1.7 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Sugar_tr PF00083.24 OAG15411.1 - 1.1e-73 248.6 25.7 1.3e-73 248.4 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15411.1 - 2.5e-11 43.1 43.5 7.4e-11 41.6 40.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG15411.1 - 0.00038 19.2 25.1 0.0016 17.1 10.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Herpes_UL49_5 PF05702.11 OAG15412.1 - 0.01 15.9 0.3 0.024 14.7 0.3 1.7 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DUF3568 PF12092.8 OAG15412.1 - 1.3 9.1 4.0 1.4 9.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) DUF4820 PF16091.5 OAG15415.1 - 0.048 13.0 2.2 0.057 12.8 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Fungal_trans PF04082.18 OAG15417.1 - 7.6e-14 51.4 0.7 1.1e-13 50.8 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15417.1 - 0.00031 20.8 7.1 0.0008 19.5 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 OAG15418.1 - 1.9e-83 280.4 0.0 2.3e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_S8 PF00082.22 OAG15419.1 - 1e-43 149.7 0.4 2.5e-43 148.4 0.4 1.6 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAG15419.1 - 6e-12 46.3 0.0 7.6e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Fn3-like domain RTA1 PF04479.13 OAG15420.1 - 1.8e-52 178.0 2.2 2.1e-52 177.8 2.2 1.0 1 0 0 1 1 1 1 RTA1 like protein MIG-14_Wnt-bd PF06664.12 OAG15420.1 - 0.0052 16.0 1.5 0.009 15.3 0.7 1.6 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Peptidase_M43 PF05572.13 OAG15421.1 - 6.4e-17 61.9 0.1 9.3e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAG15421.1 - 0.0057 17.2 0.1 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG15421.1 - 0.0085 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAG15421.1 - 0.02 14.6 0.9 0.074 12.7 0.6 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Orbi_VP1 PF05788.12 OAG15421.1 - 0.099 10.2 0.0 0.13 9.8 0.0 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) DUF3761 PF12587.8 OAG15424.1 - 0.18 12.2 1.2 11 6.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3761) DUF1031 PF06275.11 OAG15425.1 - 0.032 14.5 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Fungal_trans PF04082.18 OAG15426.1 - 5.6e-26 91.1 0.2 8.6e-26 90.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15426.1 - 4e-08 33.2 10.6 9.2e-08 32.1 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 OAG15427.1 - 1.8e-15 57.3 0.1 2.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG15427.1 - 1e-12 49.2 0.3 1.5e-12 48.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG15427.1 - 1.1e-08 34.7 0.1 1.3e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OAG15427.1 - 0.00076 19.2 0.0 0.0009 18.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 OAG15427.1 - 0.0017 17.1 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 OAG15427.1 - 0.009 16.1 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 OAG15427.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Peptidase_S9 PF00326.21 OAG15427.1 - 0.13 11.7 0.0 0.67 9.4 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG15428.1 - 0.0045 16.3 0.0 0.0074 15.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 OAG15428.1 - 0.0054 16.3 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG15428.1 - 0.12 12.9 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Amastin PF07344.11 OAG15429.1 - 0.1 12.5 3.4 0.21 11.4 3.4 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein adh_short PF00106.25 OAG15430.1 - 4.2e-21 75.3 0.1 1.4e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15430.1 - 7.9e-14 51.8 1.1 3.9e-13 49.5 1.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG15430.1 - 7.9e-08 32.0 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG15430.1 - 4.2e-06 26.8 0.1 6.9e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG15430.1 - 7.5e-06 25.9 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 OAG15430.1 - 0.0078 16.2 0.2 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L12 PF00542.19 OAG15430.1 - 0.11 12.8 0.3 0.36 11.2 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain FAD_binding_3 PF01494.19 OAG15431.1 - 1.3e-16 60.8 0.0 2.4e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG15431.1 - 2.8e-07 30.5 0.1 0.00043 20.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG15431.1 - 0.0028 16.9 0.1 0.015 14.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG15431.1 - 0.003 17.7 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG15431.1 - 0.0031 18.1 0.0 0.029 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG15431.1 - 0.011 14.6 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 OAG15431.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HET PF06985.11 OAG15432.1 - 1.9e-24 86.7 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Patatin PF01734.22 OAG15433.1 - 5.3e-20 72.5 0.7 2e-19 70.6 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase ABC_tran PF00005.27 OAG15433.1 - 0.011 16.3 0.0 0.04 14.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OAG15433.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-B_box PF00643.24 OAG15433.1 - 0.064 13.4 14.1 0.042 14.0 8.0 2.8 2 0 0 2 2 2 0 B-box zinc finger Glyco_tranf_2_3 PF13641.6 OAG15434.1 - 4.4e-11 43.1 0.1 6.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sulfotransfer_3 PF13469.6 OAG15436.1 - 0.067 13.6 0.2 0.35 11.2 0.2 2.1 1 1 0 1 1 1 0 Sulfotransferase family DUF4050 PF13259.6 OAG15437.1 - 3.8e-45 154.5 4.8 1.6e-44 152.4 4.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) E1-E2_ATPase PF00122.20 OAG15439.1 - 1.4e-34 119.2 0.8 5.8e-34 117.2 0.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG15439.1 - 5.2e-22 79.2 0.0 8.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG15439.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 OAG15439.1 - 0.11 12.8 0.2 7 7.0 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Ldi PF18566.1 OAG15440.1 - 2e-78 264.1 0.0 2.9e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Linalool dehydratase/isomerase PAP_PilO PF06864.12 OAG15440.1 - 0.039 12.8 0.4 0.064 12.1 0.4 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Glyco_hydro_36 PF17167.4 OAG15440.1 - 0.06 12.0 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Aspzincin_M35 PF14521.6 OAG15441.1 - 0.00035 21.1 0.5 0.35 11.4 0.3 2.4 2 0 0 2 2 2 2 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 OAG15441.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.8 2 0 0 2 2 2 0 Putative peptidase family TMIE PF16038.5 OAG15441.1 - 0.65 9.9 2.2 1.3 8.9 2.2 1.4 1 0 0 1 1 1 0 TMIE protein GIT_CC PF16559.5 OAG15443.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Caudo_TAP PF02413.17 OAG15443.1 - 0.55 10.4 14.5 0.45 10.6 4.5 2.8 1 1 2 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK RR_TM4-6 PF06459.12 OAG15443.1 - 1.4 8.7 8.1 1.9 8.3 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HTH_Tnp_Tc5 PF03221.16 OAG15444.1 - 2.1e-09 37.3 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG15444.1 - 0.00088 19.0 0.0 0.0021 17.7 0.0 1.7 1 1 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 OAG15444.1 - 0.0039 16.9 0.1 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 OAG15444.1 - 0.027 14.6 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OAG15444.1 - 0.06 13.6 0.3 0.2 11.9 0.0 1.9 1 1 0 2 2 2 0 Transposase GntR PF00392.21 OAG15444.1 - 0.08 12.6 0.0 1.7 8.4 0.0 2.7 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family HLH PF00010.26 OAG15445.1 - 4.7e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Red1 PF07964.11 OAG15445.1 - 2.3 6.4 14.3 3.2 5.9 14.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Dickkopf_N PF04706.12 OAG15446.1 - 0.0021 18.5 0.9 0.0021 18.5 0.9 4.4 4 0 0 4 4 4 2 Dickkopf N-terminal cysteine-rich region Cnl2_NKP2 PF09447.10 OAG15447.1 - 4.9e-24 84.2 0.6 6.2e-23 80.7 0.1 2.3 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Exonuc_VII_L PF02601.15 OAG15447.1 - 0.03 13.9 2.2 0.039 13.5 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 OAG15447.1 - 0.04 14.1 3.9 0.16 12.1 3.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FliG_C PF01706.16 OAG15447.1 - 0.083 13.1 3.7 0.86 9.8 0.5 2.7 3 0 0 3 3 3 0 FliG C-terminal domain MADF_DNA_bdg PF10545.9 OAG15447.1 - 0.2 12.0 2.1 0.35 11.2 1.6 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SOGA PF11365.8 OAG15447.1 - 0.24 12.5 3.1 0.44 11.7 3.1 1.4 1 0 0 1 1 1 0 Protein SOGA MRG PF05712.13 OAG15448.1 - 4e-51 173.2 0.9 6.2e-51 172.5 0.9 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAG15448.1 - 1e-10 41.3 2.0 1.8e-10 40.5 2.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 OAG15448.1 - 0.013 15.4 0.9 0.033 14.1 0.9 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Longin_2 PF18639.1 OAG15448.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Yeast longin domain AAA_18 PF13238.6 OAG15449.1 - 7.8e-08 32.9 0.0 3.2e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 OAG15449.1 - 0.00034 20.4 0.0 0.0018 18.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OAG15449.1 - 0.008 16.3 0.0 0.027 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG15449.1 - 0.013 15.8 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 OAG15449.1 - 0.03 14.1 0.3 0.16 11.7 0.3 1.9 1 1 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 OAG15449.1 - 0.072 13.3 0.2 0.14 12.4 0.1 1.7 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 OAG15449.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 OAG15449.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG15449.1 - 0.2 12.2 0.0 0.32 11.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RbsD_FucU PF05025.13 OAG15449.1 - 0.23 11.9 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family DUF1741 PF08427.10 OAG15450.1 - 2.6e-82 276.0 2.0 7e-82 274.6 2.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) Pyridoxal_deC PF00282.19 OAG15451.1 - 3.3e-15 55.7 0.0 5.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG15451.1 - 7e-06 25.2 0.0 1.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG15451.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FA_desaturase PF00487.24 OAG15452.1 - 0.053 13.4 1.0 0.09 12.6 1.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase IMS PF00817.20 OAG15454.1 - 4e-36 124.3 0.1 2.1e-35 121.9 0.0 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OAG15454.1 - 4.4e-17 62.9 0.1 9.3e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG15454.1 - 2.9e-05 24.1 0.0 0.0018 18.5 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif zf_UBZ PF18439.1 OAG15454.1 - 0.031 13.9 0.1 0.031 13.9 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Ribosomal_L16 PF00252.18 OAG15455.1 - 8.4e-31 106.7 0.1 1.1e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 OAG15456.1 - 2.9e-61 206.2 0.5 5.1e-60 202.2 0.2 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAG15456.1 - 2.3e-14 53.5 0.0 8e-14 51.8 0.0 2.0 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAG15456.1 - 7e-10 39.4 0.1 3.9e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG15456.1 - 8.4e-07 29.1 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OAG15456.1 - 0.00075 19.8 0.0 0.0029 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG15456.1 - 0.0027 17.9 0.3 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAG15456.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG15456.1 - 0.0057 17.2 0.5 0.03 14.9 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAG15456.1 - 0.0082 16.5 2.8 0.018 15.4 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 OAG15456.1 - 0.011 16.0 3.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.7 OAG15456.1 - 0.02 14.8 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_14 PF13173.6 OAG15456.1 - 0.053 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG15456.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAG15456.1 - 0.074 13.0 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 OAG15456.1 - 0.32 10.9 1.4 0.93 9.4 0.0 2.4 3 0 0 3 3 3 0 NTPase Tho2 PF11262.8 OAG15456.1 - 0.52 9.5 7.1 0.3 10.3 3.9 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 zf-H2C2_2 PF13465.6 OAG15457.1 - 3.6 8.2 6.5 1.3 9.6 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.16 OAG15459.1 - 5.9e-38 130.7 28.2 5.9e-38 130.7 28.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG15459.1 - 1.1e-06 28.3 2.5 1.1e-06 28.3 2.5 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB adh_short PF00106.25 OAG15460.1 - 1.7e-24 86.4 0.1 5.4e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15460.1 - 8.8e-15 54.9 0.1 1.8e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15460.1 - 2.9e-10 40.3 0.0 4.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG15460.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_N_3 PF13417.6 OAG15461.1 - 0.0018 18.6 0.1 0.0041 17.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG15461.1 - 0.002 18.3 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG15461.1 - 0.015 15.3 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LAL_C2 PF18603.1 OAG15461.1 - 0.076 13.2 0.1 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 GST_N_4 PF17172.4 OAG15461.1 - 0.12 13.2 0.0 0.26 12.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Pyr_redox_2 PF07992.14 OAG15462.1 - 1.1e-05 24.8 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG15462.1 - 1.5e-05 24.3 0.0 0.0029 16.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OAG15462.1 - 5.3e-05 21.8 0.0 0.0006 18.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG15462.1 - 0.002 17.4 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG15462.1 - 0.0033 17.5 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG15462.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG15462.1 - 0.028 15.0 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG15462.1 - 0.11 12.8 0.0 19 5.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Peptidase_A22B PF04258.13 OAG15463.1 - 2e-62 211.3 1.5 7.3e-42 143.8 0.4 2.3 2 1 0 2 2 2 2 Signal peptide peptidase SPP PF06550.11 OAG15463.1 - 0.00047 19.7 8.0 0.013 15.0 8.0 2.5 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease FAM176 PF14851.6 OAG15463.1 - 3.3 7.4 7.0 3.2 7.4 0.0 2.8 2 1 0 2 2 2 0 FAM176 family RCC1_2 PF13540.6 OAG15466.1 - 0.00021 21.0 0.4 0.0027 17.4 0.1 2.6 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OAG15466.1 - 0.0045 17.6 0.9 20 5.9 0.0 4.3 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ifi-6-16 PF06140.13 OAG15467.1 - 1.6e-09 37.5 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 OAG15467.1 - 0.00096 19.7 0.1 0.002 18.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) HET PF06985.11 OAG15469.1 - 3.2e-23 82.7 0.4 6.2e-23 81.8 0.2 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S15 PF02129.18 OAG15470.1 - 1.7e-45 155.7 2.2 1.8e-45 155.7 0.9 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG15470.1 - 1.2e-23 84.3 0.1 2.5e-23 83.2 0.1 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 OAG15470.1 - 4.4e-05 23.1 7.1 0.012 15.1 0.3 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF3425 PF11905.8 OAG15471.1 - 2.1e-14 53.5 0.1 4.5e-14 52.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) CEBP1_N PF16368.5 OAG15471.1 - 0.019 14.5 0.5 0.031 13.8 0.5 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus bZIP_1 PF00170.21 OAG15471.1 - 0.14 12.3 5.0 0.26 11.4 5.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor Tmemb_cc2 PF10267.9 OAG15473.1 - 0.00066 18.9 0.4 0.0008 18.7 0.4 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF745 PF05335.13 OAG15473.1 - 0.015 15.0 3.2 0.015 15.0 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) TMPIT PF07851.13 OAG15473.1 - 0.051 12.8 1.7 0.057 12.7 1.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF5082 PF16888.5 OAG15473.1 - 0.16 12.2 5.6 1.3 9.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 OAG15473.1 - 0.56 10.7 7.5 1.9 9.0 7.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB Pro_isomerase PF00160.21 OAG15474.1 - 8.1e-55 185.4 0.0 1.1e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.12 OAG15475.1 - 1.7e-27 95.4 0.1 2.8e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15475.1 - 1.5e-06 28.2 0.1 3.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG15475.1 - 1.3e-05 25.0 0.1 1.3e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 OAG15475.1 - 0.0012 18.4 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG15475.1 - 0.015 14.6 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG15475.1 - 0.036 12.8 0.7 0.12 11.0 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Transferase PF02458.15 OAG15476.1 - 4.6e-07 28.9 0.0 0.00013 20.8 0.0 2.4 2 1 0 2 2 2 2 Transferase family Ank_2 PF12796.7 OAG15477.1 - 4.1e-35 120.2 4.5 1.9e-09 38.0 0.0 8.2 9 0 0 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG15477.1 - 6.7e-28 96.7 0.3 4.7e-05 23.8 0.0 10.6 10 2 2 12 12 12 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG15477.1 - 2.4e-21 75.5 3.8 0.012 16.0 0.0 9.5 9 1 1 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG15477.1 - 8.2e-21 71.9 4.9 0.0064 16.9 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 OAG15477.1 - 3.6e-19 68.3 3.2 0.0008 19.8 0.0 8.9 10 0 0 10 10 10 4 Ankyrin repeat BUD22 PF09073.10 OAG15477.1 - 0.12 11.7 6.5 0.25 10.6 6.5 1.4 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 OAG15478.1 - 0.0038 16.2 4.8 0.0054 15.7 4.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG15479.1 - 6.8e-37 127.2 31.7 8.8e-37 126.8 31.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG15479.1 - 3.2e-20 72.3 56.4 3.2e-20 72.3 56.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15479.1 - 2.9e-11 42.9 8.5 2.9e-11 42.9 8.5 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter SET PF00856.28 OAG15482.1 - 1.4e-14 54.9 0.0 3e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 SET domain DUF4710 PF15828.5 OAG15483.1 - 0.18 12.0 6.0 0.23 11.6 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4710) PTP_tm PF18861.1 OAG15484.1 - 0.0013 18.8 0.2 0.0022 18.0 0.2 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J VSP PF03302.13 OAG15484.1 - 0.0014 17.6 0.1 0.002 17.1 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 OAG15484.1 - 0.012 15.0 1.1 0.029 13.8 1.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG15484.1 - 0.044 14.7 0.0 0.077 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OAG15484.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF202 PF02656.15 OAG15484.1 - 0.27 11.7 3.2 1.8 9.1 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HET PF06985.11 OAG15485.1 - 1.6e-11 44.8 1.4 1.6e-11 44.8 1.4 2.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) BNR_assoc_N PF14873.6 OAG15485.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase PTP_tm PF18861.1 OAG15486.1 - 0.0094 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J BatA PF07584.11 OAG15486.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal MLANA PF14991.6 OAG15486.1 - 0.055 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Alpha_GJ PF03229.13 OAG15486.1 - 0.18 12.4 4.8 0.095 13.3 1.2 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J SKG6 PF08693.10 OAG15486.1 - 0.18 11.2 0.7 0.36 10.3 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 OAG15486.1 - 1.6 9.4 7.7 0.22 12.2 3.1 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage AltA1 PF16541.5 OAG15487.1 - 0.00075 20.3 0.0 0.00087 20.1 0.0 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 CFEM PF05730.11 OAG15489.1 - 2.5e-09 37.1 6.1 5.5e-09 36.0 6.1 1.6 1 0 0 1 1 1 1 CFEM domain Mitofilin PF09731.9 OAG15489.1 - 0.0097 14.8 4.6 0.012 14.5 4.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ISG65-75 PF11727.8 OAG15489.1 - 0.26 10.5 6.4 0.33 10.1 5.3 1.6 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.13 OAG15489.1 - 1 10.0 8.4 0.12 13.0 0.7 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Chorismate_bind PF00425.18 OAG15490.1 - 3.7e-91 305.3 0.0 1.4e-90 303.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAG15490.1 - 2.6e-28 99.0 0.1 1.9e-24 86.5 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region FragX_IP PF05994.11 OAG15490.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Dehydrin PF00257.19 OAG15491.1 - 0.01 16.4 0.6 0.01 16.4 0.6 1.7 2 0 0 2 2 2 1 Dehydrin SH3BP5 PF05276.14 OAG15491.1 - 0.014 15.2 1.0 0.021 14.6 1.0 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF848 PF05852.11 OAG15491.1 - 0.028 14.5 1.9 0.058 13.5 1.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF5423 PF17461.2 OAG15491.1 - 0.063 12.1 9.2 0.14 11.0 3.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5423) BOF PF04076.13 OAG15491.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein SR-25 PF10500.9 OAG15491.1 - 3.2 7.3 10.3 1.1 8.8 4.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nfu_N PF08712.11 OAG15492.1 - 8.5e-29 99.5 0.0 4.9e-28 97.0 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAG15492.1 - 2.5e-27 94.8 0.1 3.9e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain MARVEL PF01284.23 OAG15493.1 - 0.02 14.9 12.7 0.031 14.3 12.7 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF4064 PF13273.6 OAG15493.1 - 0.47 10.8 6.6 0.066 13.5 0.8 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) HMGL-like PF00682.19 OAG15494.1 - 1.1e-41 143.1 0.0 2.2e-31 109.4 0.2 2.1 2 0 0 2 2 2 2 HMGL-like Fungal_trans_2 PF11951.8 OAG15495.1 - 4.9e-48 163.9 0.2 6.8e-48 163.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15495.1 - 1.3e-06 28.4 7.1 2.4e-06 27.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvdE PF03851.14 OAG15496.1 - 5.8e-114 380.0 0.0 7.6e-114 379.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE SRA1 PF07304.11 OAG15498.1 - 2.2e-10 40.5 6.7 2.2e-10 40.5 6.7 3.3 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 OAG15498.1 - 0.0027 17.4 0.2 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 OAG15498.1 - 0.013 15.5 1.8 0.035 14.2 0.3 2.4 2 1 0 2 2 2 0 Prp18 domain ANAPC4_WD40 PF12894.7 OAG15498.1 - 0.032 14.5 0.1 1.1 9.6 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG15498.1 - 0.046 14.6 4.2 8.4 7.4 0.1 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat RRM_1 PF00076.22 OAG15499.1 - 2.4e-17 62.5 0.0 3.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG15499.1 - 0.00013 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OAG15499.1 - 0.0086 15.7 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LD_cluster3 PF18180.1 OAG15499.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster3 family Nup35_RRM_2 PF14605.6 OAG15499.1 - 0.19 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.11 OAG15500.1 - 0.00047 19.9 0.1 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 OAG15501.1 - 4.4e-18 65.3 3.1 5.1e-18 65.1 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 OAG15501.1 - 0.02 14.9 1.4 0.033 14.2 1.2 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 OAG15501.1 - 0.023 14.6 0.2 0.032 14.2 0.2 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 OAG15501.1 - 0.083 12.5 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DnaJ PF00226.31 OAG15502.1 - 4.6e-09 36.3 0.2 1.8e-08 34.4 0.2 2.0 1 1 0 1 1 1 1 DnaJ domain PCEMA1 PF07418.11 OAG15502.1 - 0.0042 16.7 0.0 0.0057 16.2 0.0 1.3 1 1 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 POP1 PF06978.11 OAG15503.1 - 8e-68 228.5 6.5 1.3e-67 227.8 6.5 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAG15503.1 - 7.6e-33 112.7 1.4 2e-32 111.4 1.4 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 OAG15503.1 - 0.016 14.6 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain Sgf11 PF08209.11 OAG15504.1 - 2.4e-14 52.6 1.7 5e-14 51.6 0.1 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.6 OAG15504.1 - 0.41 10.1 2.3 11 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 OAG15504.1 - 1 9.3 8.6 0.26 11.2 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 OAG15504.1 - 2.6 8.4 4.3 6.9 7.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4171 PF13775.6 OAG15505.1 - 0.036 14.5 3.6 0.071 13.6 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Glu-tRNAGln PF02686.15 OAG15506.1 - 1.6e-11 44.3 1.0 8.6e-11 42.0 1.0 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 OAG15507.1 - 5.3e-113 377.1 18.1 6e-113 376.9 18.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OAG15507.1 - 6.8e-06 26.3 12.5 0.002 18.4 0.7 4.0 1 1 1 3 3 3 2 Tetratricopeptide repeat Hep_59 PF07052.11 OAG15507.1 - 0.089 13.6 0.3 0.18 12.6 0.3 1.6 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 TPR_2 PF07719.17 OAG15507.1 - 0.1 12.8 19.2 1.6 9.1 0.2 6.0 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG15507.1 - 0.13 12.6 18.2 0.24 11.7 0.4 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG15507.1 - 0.87 9.5 16.3 9.9 6.2 0.1 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG15507.1 - 2.3 8.4 11.7 18 5.7 0.8 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG15507.1 - 3.3 8.6 18.2 9.3 7.1 0.3 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Fasciclin PF02469.22 OAG15508.1 - 1.7e-44 151.1 0.0 1.6e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Pyridoxal_deC PF00282.19 OAG15509.1 - 8.8e-62 209.0 0.0 1.3e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG15509.1 - 0.00023 20.2 0.0 0.00048 19.2 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_7 PF03441.14 OAG15510.1 - 2e-46 158.0 0.2 3.4e-46 157.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG15510.1 - 1.7e-11 44.4 0.0 7.3e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 DNA photolyase HET PF06985.11 OAG15511.1 - 1.2e-25 90.5 0.0 2.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PTPA PF03095.15 OAG15511.1 - 0.041 13.3 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Ald_Xan_dh_C2 PF02738.18 OAG15512.1 - 3e-203 676.2 2.3 4.6e-203 675.6 2.3 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAG15512.1 - 8.8e-47 159.0 0.0 1.8e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 OAG15512.1 - 1.6e-33 115.3 0.0 3.8e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OAG15512.1 - 8.9e-33 112.5 0.1 4.3e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 OAG15512.1 - 2.3e-28 98.0 0.0 4.9e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OAG15512.1 - 1e-07 31.8 0.2 1e-07 31.8 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.16 OAG15512.1 - 0.041 14.0 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 region 3 DUF218 PF02698.17 OAG15512.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain KH_1 PF00013.29 OAG15513.1 - 1.3e-47 159.5 14.4 9.2e-16 57.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG15513.1 - 3.6e-12 46.0 6.3 0.00043 20.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAG15513.1 - 1.8e-10 40.5 2.4 0.0015 18.3 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 OAG15513.1 - 6.2e-06 26.1 0.0 0.0081 16.1 0.0 3.5 3 1 1 4 4 4 1 KH-like RNA-binding domain KH_5 PF13184.6 OAG15513.1 - 0.0088 16.1 5.7 2.4 8.3 0.2 3.5 3 0 0 3 3 3 1 NusA-like KH domain Glyco_hydro_76 PF03663.14 OAG15514.1 - 1.1e-155 518.7 26.0 1.3e-155 518.5 26.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ATP-grasp_5 PF13549.6 OAG15514.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Glyco_hydro_88 PF07470.13 OAG15514.1 - 0.13 11.3 14.1 2.3 7.2 0.9 3.1 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.21 OAG15515.1 - 1.6e-32 111.2 0.6 1.8e-32 111.0 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Chi-conotoxin PF16981.5 OAG15515.1 - 0.7 10.2 3.7 0.59 10.4 1.3 2.0 2 1 1 3 3 3 0 chi-Conotoxin or t superfamily SNARE PF05739.19 OAG15515.1 - 3.1 7.8 7.1 0.74 9.9 3.4 1.9 2 0 0 2 2 2 0 SNARE domain NAT PF04768.13 OAG15516.1 - 1.1e-38 132.6 0.4 2.2e-38 131.6 0.4 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 OAG15516.1 - 1.1e-32 113.0 0.0 2.7e-32 111.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 OAG15516.1 - 4.1e-32 111.7 0.0 8.5e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.22 OAG15516.1 - 0.00045 21.0 0.0 0.005 17.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 OAG15516.1 - 0.00088 19.4 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 OAG15516.1 - 0.02 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S15 PF02129.18 OAG15517.1 - 6e-36 124.4 0.0 3.4e-35 121.9 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG15517.1 - 3e-19 69.9 0.1 4.6e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain ADH_zinc_N PF00107.26 OAG15518.1 - 4.1e-07 30.0 0.2 6.9e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cu_amine_oxidN2 PF02727.16 OAG15520.1 - 0.062 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain TPR_1 PF00515.28 OAG15522.1 - 5.8e-52 171.5 28.9 1.1e-08 34.5 0.0 10.7 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 OAG15522.1 - 2.6e-43 142.6 23.4 4.1e-06 26.5 0.0 10.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAG15522.1 - 6.4e-37 122.7 21.8 5.2e-05 23.1 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 OAG15522.1 - 4.8e-26 89.2 17.9 2e-05 24.6 0.1 10.2 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG15522.1 - 1.9e-24 85.1 27.6 1e-06 28.3 1.0 9.4 5 2 4 9 9 9 6 TPR repeat TPR_16 PF13432.6 OAG15522.1 - 3.3e-22 78.8 14.8 2.9e-07 31.0 0.1 7.0 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG15522.1 - 1.2e-21 76.9 14.3 0.00059 20.3 0.9 6.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAG15522.1 - 6.3e-21 73.3 12.1 0.00093 19.8 0.2 8.5 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAG15522.1 - 2.6e-20 70.9 16.0 0.0097 15.9 0.1 9.0 9 1 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG15522.1 - 5.4e-20 71.5 22.3 2.6e-05 24.4 0.6 7.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 OAG15522.1 - 7.2e-18 64.0 23.7 0.014 16.0 0.6 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAG15522.1 - 4.5e-13 49.1 11.7 0.00061 19.9 0.1 6.1 1 1 7 8 8 8 5 Tetratricopeptide repeat TPR_15 PF13429.6 OAG15522.1 - 3.6e-10 39.5 10.9 0.051 12.8 3.0 5.1 1 1 1 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG15522.1 - 4e-08 33.4 2.9 4e-08 33.4 2.9 3.6 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OAG15522.1 - 4.2e-06 26.6 7.1 0.79 9.4 0.0 4.5 4 2 0 4 4 4 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 OAG15522.1 - 0.0042 17.5 8.2 6.2 7.3 0.0 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DUF2225 PF09986.9 OAG15522.1 - 0.0061 16.3 3.8 0.16 11.6 0.0 3.0 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 OAG15522.1 - 0.13 12.6 5.2 0.35 11.2 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG15522.1 - 0.95 9.4 21.3 5.7 7.0 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.6 OAG15522.1 - 1.7 8.0 20.0 9 5.6 0.8 5.1 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP NuiA PF07924.11 OAG15523.1 - 1.1e-05 25.8 1.5 0.00088 19.7 0.1 2.5 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein Phage_Mu_Gp45 PF06890.12 OAG15523.1 - 0.16 11.7 0.6 0.43 10.3 0.2 1.9 2 1 0 2 2 2 0 Bacteriophage Mu Gp45 protein SKN1 PF03935.15 OAG15524.1 - 8.1e-230 763.4 1.3 9.5e-230 763.2 1.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FAM193_C PF15914.5 OAG15525.1 - 0.046 13.5 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 FAM193 family C-terminal Enterotoxin_b PF01376.18 OAG15525.1 - 0.062 13.5 0.1 0.075 13.2 0.1 1.1 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain CytB6-F_Fe-S PF08802.10 OAG15525.1 - 0.14 12.2 1.0 0.14 12.2 1.0 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DASH_Hsk3 PF08227.11 OAG15526.1 - 5.1e-18 65.2 3.6 6.4e-18 64.8 3.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ADIP PF11559.8 OAG15526.1 - 0.042 13.9 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 OAG15526.1 - 0.1 13.2 1.1 0.15 12.7 1.1 1.3 1 0 0 1 1 1 0 SlyX GATA PF00320.27 OAG15527.1 - 4.1e-16 58.3 2.5 7.6e-16 57.4 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAG15527.1 - 2e-12 46.7 2.4 3.6e-12 45.9 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DJ-1_PfpI PF01965.24 OAG15528.1 - 1.8e-08 34.4 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.22 OAG15530.1 - 5.7e-43 147.3 0.0 7.1e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4199 PF13858.6 OAG15530.1 - 0.00079 19.9 0.3 0.0079 16.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Sugar_tr PF00083.24 OAG15532.1 - 2.2e-78 264.2 27.0 2.8e-78 263.8 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15532.1 - 2.7e-26 92.3 28.9 2.7e-26 92.3 28.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily BNR_2 PF13088.6 OAG15533.1 - 0.00016 21.1 0.1 0.00091 18.6 0.1 1.9 1 1 1 2 2 2 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 OAG15533.1 - 0.078 11.8 1.1 10 4.8 0.1 2.8 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, Abhydrolase_2 PF02230.16 OAG15534.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 OAG15534.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 OAG15534.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG15534.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family CENP-Q PF13094.6 OAG15535.1 - 1.7e-32 113.0 7.7 1.7e-32 113.0 7.7 2.4 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cullin_Nedd8 PF10557.9 OAG15535.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain YqhG PF11079.8 OAG15535.1 - 0.074 12.0 0.7 0.11 11.4 0.7 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Prominin PF05478.11 OAG15535.1 - 0.24 9.3 5.5 0.059 11.3 1.2 2.1 2 1 0 2 2 2 0 Prominin RACo_linker PF17650.1 OAG15535.1 - 0.24 11.3 3.2 6.3 6.7 0.1 2.6 2 1 1 3 3 3 0 RACo linker region Fib_alpha PF08702.10 OAG15535.1 - 0.35 11.0 9.5 2.2 8.5 3.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family 4HB_MCP_1 PF12729.7 OAG15535.1 - 2.3 7.7 6.2 13 5.3 1.2 2.8 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 OAG15535.1 - 4.9 7.2 7.6 2.3 8.3 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 OAG15535.1 - 6.7 7.4 8.1 2.6 8.7 2.4 2.9 2 1 2 4 4 4 0 Initiation control protein YabA Zn_clus PF00172.18 OAG15536.1 - 1.1e-05 25.5 8.2 2e-05 24.6 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.10 OAG15537.1 - 2.8e-75 253.4 30.1 1.7e-74 250.8 10.8 5.0 5 2 1 6 6 6 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 OAG15537.1 - 0.00052 20.2 17.9 0.0006 20.1 0.2 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG15537.1 - 0.0058 16.8 1.9 14 6.2 0.3 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG15537.1 - 0.011 16.5 5.8 6.4 7.9 0.2 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG15537.1 - 0.014 15.9 4.4 0.87 10.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG15537.1 - 0.024 15.3 1.9 8.3 7.2 0.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG15537.1 - 0.06 13.2 6.3 16 5.6 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG15537.1 - 0.072 13.8 6.4 0.27 12.0 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG15537.1 - 0.65 10.2 16.6 0.34 11.1 1.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 OAG15537.1 - 5.2 7.5 6.4 27 5.3 0.7 3.8 4 0 0 4 4 4 0 PPR repeat HMG_box PF00505.19 OAG15538.1 - 3.1e-23 82.0 1.3 6.6e-23 80.9 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG15538.1 - 5.7e-09 36.4 1.1 1.4e-08 35.2 1.1 1.7 1 0 0 1 1 1 1 HMG-box domain Abhydrolase_3 PF07859.13 OAG15539.1 - 2.7e-37 128.7 0.0 1.3e-25 90.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG15539.1 - 0.0042 16.0 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase zf-RING_5 PF14634.6 OAG15540.1 - 0.00087 19.2 9.5 0.0015 18.4 7.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain FYVE PF01363.21 OAG15540.1 - 0.0078 16.3 3.5 0.018 15.2 3.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 OAG15540.1 - 0.0088 16.4 8.2 0.015 15.6 6.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG15540.1 - 0.033 14.2 4.6 0.033 14.2 4.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG15540.1 - 0.1 12.5 7.2 0.42 10.5 7.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG15540.1 - 0.21 11.8 6.8 1.1 9.5 6.8 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG15540.1 - 4.5 7.2 10.4 2e+02 1.9 9.9 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Chitin_bind_1 PF00187.19 OAG15541.1 - 8.9e-22 77.3 63.1 2.4e-12 47.1 14.0 3.9 3 1 0 3 3 3 3 Chitin recognition protein Abhydrolase_2 PF02230.16 OAG15542.1 - 1.2e-59 201.7 0.0 1.4e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG15542.1 - 3.5e-06 26.6 0.9 0.00041 19.9 0.1 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG15542.1 - 4.7e-06 26.0 0.6 0.021 14.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 OAG15542.1 - 6.8e-05 22.5 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG15542.1 - 0.00011 22.1 0.1 0.051 13.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 OAG15542.1 - 0.00022 20.9 0.0 0.0015 18.2 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG15542.1 - 0.0012 19.5 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 OAG15542.1 - 0.037 13.5 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase BAAT_C PF08840.11 OAG15542.1 - 0.042 13.8 0.3 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.22 OAG15542.1 - 0.044 13.7 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 OAG15542.1 - 0.056 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.16 OAG15542.1 - 0.11 12.2 0.1 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Esterase PF00756.20 OAG15542.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Putative esterase HhH-GPD PF00730.25 OAG15543.1 - 5.1e-06 26.9 0.0 1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG15543.1 - 0.005 16.7 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG15543.1 - 0.026 15.1 0.0 0.43 11.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.25 OAG15544.1 - 1e-43 149.1 0.8 1.4e-43 148.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15544.1 - 5.9e-39 134.0 0.1 9.6e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15544.1 - 7.6e-07 29.2 1.4 3e-06 27.3 1.2 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG15544.1 - 0.00013 21.2 1.0 0.00024 20.3 1.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 OAG15544.1 - 0.0037 17.3 0.1 0.009 16.0 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 OAG15544.1 - 0.0041 17.2 0.1 0.0069 16.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAG15544.1 - 0.057 13.1 0.8 0.14 11.8 0.3 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAG15544.1 - 0.074 12.9 0.7 0.25 11.2 0.4 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG15544.1 - 0.09 13.3 1.5 4.9 7.8 0.8 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 OAG15545.1 - 1.3e-11 45.4 0.1 2.3e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG15545.1 - 2.6e-09 37.5 0.1 2.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain HLH PF00010.26 OAG15546.1 - 2.9e-14 52.7 0.2 6e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PARM PF17061.5 OAG15546.1 - 0.39 10.8 17.6 0.53 10.4 17.6 1.1 1 0 0 1 1 1 0 PARM Zn_clus PF00172.18 OAG15549.1 - 3.2e-08 33.5 6.7 5.2e-08 32.9 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 OAG15551.1 - 8.7e-13 47.3 0.0 5.1e-12 44.8 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 OAG15551.1 - 0.00017 21.9 0.0 0.0051 17.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA Atg14 PF10186.9 OAG15552.1 - 0.00017 20.8 1.3 0.00036 19.7 0.3 1.9 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TraC PF07820.12 OAG15552.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.5 3 0 0 3 3 3 0 TraC-like protein TnpV PF14198.6 OAG15552.1 - 0.48 10.4 1.9 6.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Transposon-encoded protein TnpV DUF724 PF05266.14 OAG15552.1 - 0.58 9.9 8.2 0.2 11.5 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) FUSC PF04632.12 OAG15552.1 - 0.97 7.9 15.3 2.3 6.7 8.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4407 PF14362.6 OAG15552.1 - 1.6 8.0 9.2 4.7 6.5 9.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mcm10 PF09332.11 OAG15552.1 - 3.5 6.9 6.1 1.2 8.5 0.1 2.4 3 0 0 3 3 3 0 Mcm10 replication factor Pox_A_type_inc PF04508.12 OAG15552.1 - 3.7 7.6 9.4 2.6 8.1 0.1 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 OAG15552.1 - 8.3 6.7 12.5 3.4 7.9 0.0 3.7 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 HET PF06985.11 OAG15553.1 - 2.9e-24 86.1 0.3 8.5e-24 84.6 0.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5475 PF17569.2 OAG15553.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5475) Cutinase PF01083.22 OAG15554.1 - 1.9e-51 174.5 10.6 2.2e-51 174.3 10.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG15554.1 - 1.4e-06 28.0 0.1 1.9e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG15554.1 - 0.0098 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.20 OAG15554.1 - 0.049 13.3 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG15554.1 - 0.055 14.1 0.1 0.068 13.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OAG15554.1 - 0.081 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAG15554.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 OAG15554.1 - 0.12 12.2 0.4 0.24 11.2 0.3 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_2 PF01674.18 OAG15554.1 - 0.13 11.7 5.8 0.37 10.3 5.8 1.7 1 1 0 1 1 1 0 Lipase (class 2) DAO PF01266.24 OAG15555.1 - 4e-30 105.6 0.7 1.4e-29 103.8 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG15555.1 - 9.6e-05 22.4 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG15555.1 - 0.00017 21.7 0.0 0.002 18.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG15555.1 - 0.00026 20.0 0.1 0.0031 16.4 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 OAG15555.1 - 0.00041 19.6 0.3 0.0011 18.2 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG15555.1 - 0.00055 19.3 0.0 0.4 9.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG15555.1 - 0.015 14.4 0.3 3.6 6.5 0.1 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG15555.1 - 0.04 13.2 0.5 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG15555.1 - 0.051 12.8 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAG15555.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_3_C PF01915.22 OAG15557.1 - 6.7e-53 179.7 0.2 1.1e-52 178.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG15557.1 - 1.8e-45 155.7 0.0 2.6e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG15557.1 - 4.9e-23 81.0 2.1 1.3e-22 79.6 2.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 OAG15557.1 - 0.028 13.5 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain ASH PF15780.5 OAG15557.1 - 0.061 13.5 0.1 0.56 10.5 0.1 2.4 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin His_Phos_1 PF00300.22 OAG15559.1 - 6.8e-27 94.4 0.0 1.4e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF5585 PF17823.1 OAG15559.1 - 0.024 13.6 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Zn_clus PF00172.18 OAG15561.1 - 7e-05 22.9 14.1 7e-05 22.9 14.1 4.7 3 1 2 5 5 5 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SSI PF00720.17 OAG15561.1 - 0.029 14.3 1.0 0.095 12.7 1.0 1.9 1 0 0 1 1 1 0 Subtilisin inhibitor-like TauD PF02668.16 OAG15562.1 - 1.3e-59 202.2 1.1 1.7e-59 201.9 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG15563.1 - 3.2e-21 75.7 13.7 4.2e-21 75.3 13.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 OAG15564.1 - 1e-32 113.2 0.0 1.2e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15564.1 - 3.6e-24 85.6 0.0 4.5e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15564.1 - 6.6e-06 26.2 0.6 0.00013 21.9 0.5 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG15564.1 - 3.4e-05 23.4 0.0 4.9e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG15564.1 - 0.00017 21.1 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 OAG15564.1 - 0.0048 16.0 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain COesterase PF00135.28 OAG15565.1 - 3.7e-74 250.5 0.0 6.2e-74 249.7 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family HbrB PF08539.11 OAG15566.1 - 8e-51 172.4 0.0 2.1e-50 171.0 0.0 1.8 1 0 0 1 1 1 1 HbrB-like SUIM_assoc PF16619.5 OAG15566.1 - 3.5e-05 23.8 0.0 0.52 10.4 0.0 5.1 5 1 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 Gon7 PF08738.10 OAG15567.1 - 2.7e-12 46.7 3.7 7.1e-10 38.9 0.3 2.0 1 1 1 2 2 2 2 Gon7 family Vps39_2 PF10367.9 OAG15568.1 - 4.9e-33 113.8 0.0 1.3e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 OAG15568.1 - 2e-31 108.5 0.1 9.5e-31 106.3 0.0 2.3 3 0 0 3 3 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 OAG15568.1 - 2.4e-20 73.3 0.0 1.6e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 CNH domain TPR_16 PF13432.6 OAG15568.1 - 0.0016 19.0 0.2 0.66 10.7 0.2 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG15568.1 - 0.002 17.9 7.3 2.1 8.3 2.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 OAG15568.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_8 PF13181.6 OAG15568.1 - 0.0082 16.3 4.3 0.86 10.0 0.4 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG15568.1 - 0.023 14.6 0.9 16 5.6 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG15568.1 - 0.026 14.6 7.3 3 8.2 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG15568.1 - 0.039 14.2 1.9 0.46 10.8 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAG15568.1 - 0.12 12.6 6.4 16 5.9 0.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 OAG15568.1 - 0.16 12.2 0.3 0.61 10.3 0.1 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_3 PF07720.12 OAG15568.1 - 0.64 10.1 5.9 12 6.0 1.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG15568.1 - 1.3 9.6 6.5 2.3 8.8 1.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OAG15569.1 - 0.0024 17.9 3.5 0.96 9.5 0.1 3.5 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus MaAIMP_sms PF16951.5 OAG15569.1 - 0.018 14.8 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit Collagen_mid PF15984.5 OAG15569.1 - 0.048 13.4 6.9 0.18 11.6 0.4 2.8 2 1 0 2 2 2 0 Bacterial collagen, middle region EspB PF05802.11 OAG15569.1 - 0.14 12.1 2.8 0.61 10.1 0.3 2.6 2 1 0 2 2 2 0 Enterobacterial EspB protein CCD PF07860.11 OAG15569.1 - 0.56 10.3 1.9 9.1 6.3 0.0 3.4 3 0 0 3 3 3 0 WisP family C-Terminal Region ApoLp-III PF07464.11 OAG15569.1 - 1.2 9.2 3.2 9.5 6.3 0.1 3.4 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 OAG15569.1 - 4.4 7.6 6.9 8.3 6.7 0.1 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Acetyltransf_1 PF00583.25 OAG15571.1 - 8e-08 32.5 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG15571.1 - 1.2e-07 31.8 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG15571.1 - 1.4e-07 31.8 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nkap_C PF06047.11 OAG15571.1 - 0.032 14.3 1.5 0.11 12.6 1.5 1.7 1 1 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain Antimicrobial17 PF08129.11 OAG15572.1 - 0.062 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta enterocin family Cutinase PF01083.22 OAG15573.1 - 1.2e-43 149.2 0.0 1.7e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Cutinase YAcAr PF10686.9 OAG15573.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family PE-PPE PF08237.11 OAG15573.1 - 0.028 13.9 0.1 0.076 12.5 0.1 1.6 1 1 1 2 2 2 0 PE-PPE domain GCN5L1 PF06320.13 OAG15574.1 - 2e-21 76.2 3.0 2.5e-21 76.0 3.0 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.8 OAG15574.1 - 0.0072 15.8 2.3 0.008 15.6 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4407 PF14362.6 OAG15574.1 - 0.37 10.1 5.4 0.41 10.0 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 OAG15574.1 - 0.63 10.6 3.9 10 6.8 3.9 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF913 PF06025.12 OAG15575.1 - 4.5e-127 424.0 0.0 4.5e-127 424.0 0.0 7.0 7 0 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OAG15575.1 - 5e-108 361.7 0.0 5e-108 361.7 0.0 5.2 5 1 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 OAG15575.1 - 1.9e-93 313.3 0.2 3.3e-93 312.6 0.2 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 OAG15575.1 - 8.7e-30 101.3 20.4 6.4e-11 41.3 0.8 4.0 3 0 0 3 3 3 3 Ubiquitin binding region MIEAP PF16026.5 OAG15575.1 - 0.84 9.8 3.9 6.9 6.8 2.8 3.1 2 0 0 2 2 2 0 Mitochondria-eating protein p450 PF00067.22 OAG15576.1 - 0.008 15.0 0.0 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_3 PF05899.12 OAG15577.1 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 OAG15577.1 - 1.7e-05 24.6 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 OAG15577.1 - 0.075 12.8 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Cupin domain MIOX PF05153.15 OAG15578.1 - 2.7e-122 407.1 3.7 3.9e-122 406.6 3.7 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase Cytochrom_C_2 PF01322.20 OAG15578.1 - 0.0047 17.8 2.7 0.009 16.9 2.7 1.5 1 0 0 1 1 1 1 Cytochrome C' NOG1_N PF17835.1 OAG15578.1 - 0.24 11.3 2.7 0.62 10.0 0.1 2.5 2 1 0 2 2 2 0 NOG1 N-terminal helical domain Aldo_ket_red PF00248.21 OAG15579.1 - 3e-45 154.7 0.3 2.9e-37 128.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family adh_short_C2 PF13561.6 OAG15580.1 - 2.7e-54 184.2 0.1 3.4e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15580.1 - 5.7e-53 179.3 0.1 8.6e-53 178.7 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG15580.1 - 1.6e-12 47.7 0.6 5.2e-12 46.1 0.2 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG15580.1 - 5.3e-05 22.8 0.0 8.8e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 OAG15580.1 - 0.003 17.3 0.0 0.038 13.7 0.0 2.1 2 1 0 2 2 2 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 OAG15580.1 - 0.013 14.8 0.1 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 OAG15580.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family AAA_31 PF13614.6 OAG15580.1 - 0.022 14.7 0.4 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain GDP_Man_Dehyd PF16363.5 OAG15580.1 - 0.026 14.0 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG15580.1 - 0.048 12.7 0.1 1 8.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_N PF08240.12 OAG15581.1 - 1e-27 96.2 0.3 1e-27 96.2 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15581.1 - 1.7e-17 63.6 0.8 3.3e-17 62.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG15581.1 - 5.7e-11 42.3 2.4 7.9e-06 25.5 0.0 2.3 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG15581.1 - 0.0046 16.3 1.9 0.0096 15.2 1.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG15581.1 - 0.0079 17.2 0.1 0.044 14.8 0.0 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ThiF PF00899.21 OAG15581.1 - 0.019 14.4 0.3 0.039 13.3 0.3 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 OAG15581.1 - 0.047 13.3 0.4 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG15581.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG15581.1 - 0.26 11.3 0.9 1.4 8.9 0.3 2.4 1 1 2 3 3 3 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 OAG15582.1 - 1.3e-25 90.6 0.4 2.5e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG15582.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 OAG15582.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_3 PF03447.16 OAG15582.1 - 0.11 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain tRNA-synt_1 PF00133.22 OAG15583.1 - 1.2e-32 112.9 0.1 1.6e-25 89.5 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAG15583.1 - 3.6e-13 49.1 0.0 3.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG15583.1 - 7e-13 48.8 1.7 2.5e-12 47.0 1.7 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG15583.1 - 1e-08 34.9 0.1 2.8e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Prenyltransf PF01255.19 OAG15583.1 - 0.087 12.3 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase ATP-synt_ab PF00006.25 OAG15586.1 - 9.1e-67 224.8 0.0 1.2e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAG15586.1 - 5.6e-14 52.4 0.5 1.1e-13 51.5 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LIM_bind PF01803.16 OAG15587.1 - 5.4e-62 209.5 0.0 5.4e-62 209.5 0.0 4.5 3 1 0 3 3 3 1 LIM-domain binding protein DUF4407 PF14362.6 OAG15587.1 - 0.00048 19.6 23.1 0.0074 15.7 22.4 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Pkinase PF00069.25 OAG15588.1 - 4.5e-30 104.9 0.0 1.6e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15588.1 - 2.1e-21 76.4 0.0 1.3e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L28 PF00830.19 OAG15589.1 - 1.7e-15 57.0 1.0 1.7e-15 57.0 1.0 2.0 2 0 0 2 2 2 1 Ribosomal L28 family CusF_Ec PF11604.8 OAG15589.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF PTH2 PF01981.16 OAG15590.1 - 1.4e-47 160.8 0.1 1.9e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 CENP-B_dimeris PF09026.10 OAG15590.1 - 0.042 14.2 0.7 0.069 13.5 0.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tom5 PF10642.9 OAG15590.1 - 0.74 9.9 6.7 25 5.0 0.6 3.3 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase GET2 PF08690.10 OAG15591.1 - 5e-25 88.8 7.3 4e-23 82.6 7.3 2.1 1 1 0 1 1 1 1 GET complex subunit GET2 TRAM_LAG1_CLN8 PF03798.16 OAG15591.1 - 0.02 14.6 0.4 0.031 14.0 0.4 1.3 1 0 0 1 1 1 0 TLC domain Tim17 PF02466.19 OAG15591.1 - 0.15 12.4 1.2 0.34 11.3 1.2 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LAM_C PF12544.8 OAG15592.1 - 2.9e-05 24.2 0.0 7.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 OAG15592.1 - 0.00032 21.1 0.1 0.0027 18.1 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 OAG15592.1 - 0.0031 17.6 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Couple_hipA PF13657.6 OAG15592.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 HipA N-terminal domain Fer4_12 PF13353.6 OAG15592.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain TPR_12 PF13424.6 OAG15593.1 - 0.0012 19.1 1.4 0.0072 16.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box-like_2 PF13013.6 OAG15593.1 - 0.0051 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain TPR_2 PF07719.17 OAG15593.1 - 0.0074 16.3 0.1 0.0074 16.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat PMI_typeI PF01238.21 OAG15594.1 - 2.4e-72 244.2 0.0 1.8e-71 241.3 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 OAG15594.1 - 1.5e-08 34.2 0.0 0.00038 20.1 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG15594.1 - 3.4e-06 27.0 0.0 0.00042 20.2 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG15594.1 - 0.13 12.0 0.1 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Glyco_transf_34 PF05637.12 OAG15595.1 - 3.8e-66 223.2 0.0 4.5e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MMR_HSR1 PF01926.23 OAG15596.1 - 0.00012 22.1 0.0 0.54 10.4 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase Aminotran_1_2 PF00155.21 OAG15597.1 - 6.6e-87 292.0 0.0 7.6e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RE_NgoFVII PF09565.10 OAG15597.1 - 0.17 11.2 0.1 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 NgoFVII restriction endonuclease Hpt PF01627.23 OAG15598.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Hpt domain Erp_C PF06780.11 OAG15598.1 - 0.023 14.7 7.7 0.34 10.9 3.4 2.4 1 1 1 2 2 2 0 Erp protein C-terminus NuA4 PF09340.10 OAG15598.1 - 0.029 14.2 2.3 0.031 14.2 1.1 1.8 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF4844 PF16133.5 OAG15598.1 - 0.043 14.4 2.8 0.15 12.6 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) AKAP7_NLS PF10469.9 OAG15599.1 - 5.9e-23 81.8 0.0 7.5e-21 75.0 0.2 2.2 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 OAG15599.1 - 0.011 15.9 2.4 1.6 9.0 0.4 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase NUC130_3NT PF08158.12 OAG15600.1 - 0.48 10.8 4.9 13 6.2 0.1 3.2 3 1 0 3 3 3 0 NUC130/3NT domain DASH_Duo1 PF08651.10 OAG15600.1 - 1.2 8.9 7.7 0.17 11.7 2.6 2.1 2 1 0 2 2 2 0 DASH complex subunit Duo1 Vps53_N PF04100.12 OAG15600.1 - 3.1 6.7 6.6 4.9 6.0 0.9 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal Syntaxin-6_N PF09177.11 OAG15600.1 - 8.3 7.0 8.2 2.7 8.6 0.5 3.0 3 1 0 3 3 3 0 Syntaxin 6, N-terminal GST_N_3 PF13417.6 OAG15601.1 - 3.4e-12 46.6 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG15601.1 - 6.2e-11 42.4 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG15601.1 - 2.9e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG15601.1 - 0.00036 20.7 0.0 0.00079 19.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG15601.1 - 0.0052 17.0 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG15601.1 - 0.0056 16.7 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sel1 PF08238.12 OAG15602.1 - 2e-41 139.5 26.0 1.2e-07 32.2 0.3 7.7 7 0 0 7 7 7 7 Sel1 repeat SRC-1 PF08832.10 OAG15602.1 - 0.032 15.3 0.4 0.39 11.8 0.0 2.6 2 0 0 2 2 2 0 Steroid receptor coactivator TPR_16 PF13432.6 OAG15602.1 - 0.051 14.2 9.0 0.63 10.7 0.3 4.0 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG15602.1 - 0.077 13.7 8.5 7.3 7.5 0.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG15602.1 - 0.35 11.4 4.8 1.9 9.0 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CBP4 PF07960.11 OAG15603.1 - 1.2e-27 96.3 1.3 1.3e-27 96.2 1.3 1.0 1 0 0 1 1 1 1 CBP4 ERCC4 PF02732.15 OAG15604.1 - 1.3e-20 74.2 0.0 2.7e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain eIF-1a PF01176.19 OAG15605.1 - 4.2e-22 77.7 0.1 5.9e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sigma70_r2 PF04542.14 OAG15606.1 - 0.063 13.0 1.8 0.1 12.4 0.9 1.8 2 0 0 2 2 2 0 Sigma-70 region 2 Aminotran_4 PF01063.19 OAG15607.1 - 6.5e-15 55.6 0.0 5.3e-10 39.5 0.0 3.1 2 1 0 2 2 2 2 Amino-transferase class IV Sugar_tr PF00083.24 OAG15608.1 - 6.2e-81 272.6 18.1 7.6e-81 272.3 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15608.1 - 3.5e-19 68.9 27.8 3.3e-14 52.6 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG15608.1 - 7.2e-07 28.1 15.1 1e-05 24.3 1.3 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAG15608.1 - 0.21 10.4 17.0 0.24 10.2 7.6 2.3 2 0 0 2 2 2 0 MFS_1 like family tRNA-synt_1b PF00579.25 OAG15609.1 - 9.7e-22 77.6 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PRELI PF04707.14 OAG15610.1 - 1.2e-21 77.1 0.0 5.2e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Glyco_hydro_35 PF01301.19 OAG15612.1 - 9.7e-88 294.8 0.4 2e-87 293.7 0.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG15612.1 - 4.7e-56 188.3 9.4 1.5e-31 109.3 0.0 3.5 4 1 1 5 5 5 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAG15612.1 - 1.5e-53 181.3 7.5 2.4e-53 180.6 7.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAG15612.1 - 4.8e-25 86.9 0.0 9.9e-25 85.9 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Sugar_tr PF00083.24 OAG15613.1 - 1e-74 252.1 20.8 1.2e-74 251.9 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15613.1 - 1.5e-17 63.6 34.8 8.3e-13 48.0 14.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG15613.1 - 3.6 6.3 17.0 0.28 10.0 7.7 3.1 2 2 1 3 3 3 0 MFS_1 like family Baculo_PEP_C PF04513.12 OAG15614.1 - 0.011 15.8 18.2 0.4 10.7 0.5 3.4 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.8 OAG15614.1 - 0.76 9.0 9.9 0.051 12.8 3.1 2.3 1 1 2 3 3 3 0 Invariant surface glycoprotein YtxH PF12732.7 OAG15614.1 - 3.3 8.3 5.0 13 6.4 0.1 3.2 2 1 0 2 2 2 0 YtxH-like protein Fzo_mitofusin PF04799.13 OAG15614.1 - 5.4 6.5 17.3 0.74 9.3 4.9 3.2 2 2 2 4 4 4 0 fzo-like conserved region Snapin_Pallidin PF14712.6 OAG15614.1 - 5.8 7.4 27.1 2.1 8.8 2.8 5.2 4 1 1 5 5 5 0 Snapin/Pallidin Lyase_1 PF00206.20 OAG15615.1 - 5.4e-112 374.2 0.0 7.4e-112 373.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAG15615.1 - 3.3e-20 72.2 0.1 6.7e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus zf-rbx1 PF12678.7 OAG15616.1 - 5.1e-07 29.9 6.6 8.1e-07 29.2 6.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG15616.1 - 1.8e-06 28.2 7.7 3.8e-06 27.1 7.7 1.5 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG15616.1 - 2.9e-06 27.2 1.1 5e-06 26.5 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG15616.1 - 1.5e-05 24.8 6.3 2.4e-05 24.1 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG15616.1 - 0.00014 21.8 3.0 0.00031 20.7 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG15616.1 - 0.0008 19.3 6.4 0.0013 18.6 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG15616.1 - 0.011 15.8 2.9 0.025 14.7 2.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAG15616.1 - 0.023 14.6 6.0 0.08 12.8 6.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OAG15616.1 - 0.2 11.8 5.1 0.36 11.0 5.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OAG15616.1 - 0.73 9.7 7.3 10 6.1 7.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG15616.1 - 1.4 8.9 9.7 8.1 6.4 9.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG15616.1 - 3.3 7.6 6.0 2.3 8.1 2.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 OAG15617.1 - 3.9e-59 200.2 0.0 2.6e-58 197.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15617.1 - 3.4e-29 101.9 0.1 1.8e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG15617.1 - 0.0018 17.7 0.1 0.0082 15.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG15617.1 - 0.0019 18.1 2.3 0.07 13.0 0.9 3.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 OAG15617.1 - 0.0081 16.8 2.4 0.013 16.2 0.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAG15617.1 - 0.013 14.4 0.0 0.033 13.2 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAG15617.1 - 0.014 14.8 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 OAG15618.1 - 1.8e-23 83.1 0.0 1e-11 44.7 0.0 2.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG15618.1 - 2.1e-20 74.1 0.2 2.1e-20 74.1 0.2 4.4 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 OAG15618.1 - 2.2e-09 37.5 6.9 4.1e-06 26.8 0.0 4.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAG15618.1 - 1.3e-07 31.8 0.5 0.0033 17.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG15618.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG15618.1 - 0.015 15.8 0.0 0.015 15.8 0.0 5.1 3 2 0 3 3 1 0 ABC transporter AAA PF00004.29 OAG15618.1 - 0.021 15.2 0.0 0.13 12.7 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 OAG15618.1 - 0.045 13.4 0.0 0.045 13.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OAG15618.1 - 0.083 13.2 0.9 6.9 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAG15618.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 OAG15618.1 - 1.9 8.3 6.9 1.3 8.9 0.1 3.3 3 1 0 3 3 3 0 RsgA GTPase Adeno_E3_CR2 PF02439.15 OAG15620.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 OAG15620.1 - 0.053 13.4 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Rifin DUF3769 PF12600.8 OAG15620.1 - 0.084 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) ERGIC_N PF13850.6 OAG15620.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MRAP PF15183.6 OAG15620.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Tyrosinase PF00264.20 OAG15622.1 - 3.1e-53 181.3 0.4 4.2e-53 180.9 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BTB PF00651.31 OAG15624.1 - 8.9e-05 22.7 0.3 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF2505 PF10698.9 OAG15624.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Bromodomain PF00439.25 OAG15625.1 - 8e-08 32.2 0.0 4.8e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Bromodomain SlyX PF04102.12 OAG15626.1 - 0.0011 19.5 1.5 0.0011 19.5 1.5 1.9 1 1 1 2 2 2 1 SlyX Spc7 PF08317.11 OAG15626.1 - 0.0036 16.3 1.0 0.0043 16.0 1.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Sugarporin_N PF11471.8 OAG15626.1 - 0.0053 16.7 5.4 0.013 15.5 5.4 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Csm1_N PF18504.1 OAG15626.1 - 0.11 12.8 3.2 0.18 12.2 3.0 1.5 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF4855 PF16147.5 OAG15626.1 - 0.17 10.9 0.1 0.36 9.9 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4855) GrpE PF01025.19 OAG15626.1 - 0.92 9.2 5.3 1.3 8.7 5.3 1.2 1 0 0 1 1 1 0 GrpE ATP_transf PF09830.9 OAG15627.1 - 3e-14 52.9 0.1 5.9e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 OAG15627.1 - 0.056 13.2 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) Peptidase_M14 PF00246.24 OAG15628.1 - 6.5e-83 278.9 0.3 8.1e-83 278.5 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase HET PF06985.11 OAG15629.1 - 2e-13 50.9 11.2 6.6e-11 42.8 4.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HlyIII PF03006.20 OAG15630.1 - 2.5e-49 168.0 20.4 3e-49 167.8 20.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related GET2 PF08690.10 OAG15630.1 - 0.029 14.0 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DC_STAMP PF07782.13 OAG15630.1 - 0.39 10.5 5.2 0.31 10.8 3.0 1.8 3 0 0 3 3 3 0 DC-STAMP-like protein Peptidase_S8 PF00082.22 OAG15631.1 - 2.5e-17 63.1 0.1 4.9e-17 62.1 0.1 1.5 1 1 0 1 1 1 1 Subtilase family LeuA_dimer PF08502.10 OAG15631.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain FA_desaturase PF00487.24 OAG15632.1 - 1.5e-23 84.0 18.3 3.1e-23 82.9 18.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG15632.1 - 8.9e-05 22.7 0.0 0.00031 21.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) GCP_C_terminal PF04130.13 OAG15633.1 - 6.6e-96 321.4 0.2 1.7e-95 320.1 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG15633.1 - 6e-79 265.8 0.0 4.2e-78 263.1 0.0 2.3 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal AMP-binding PF00501.28 OAG15634.1 - 7.3e-35 120.4 0.8 1.2e-32 113.1 0.1 2.8 3 0 0 3 3 3 2 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG15634.1 - 2.5e-34 118.6 0.0 3.7e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG15634.1 - 2.1e-09 37.2 0.2 1.9e-08 34.0 0.1 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG15634.1 - 1.7e-08 34.7 0.0 4.7e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 OAG15634.1 - 0.0012 18.4 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG15634.1 - 0.002 17.3 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG15634.1 - 0.0035 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG15634.1 - 0.0073 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 OAG15634.1 - 0.024 14.8 0.0 0.083 13.0 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAG15634.1 - 0.044 14.2 0.0 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3176 PF11374.8 OAG15635.1 - 1.4e-29 102.4 0.6 6.1e-29 100.4 0.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3176 PF11374.8 OAG15637.1 - 6.3e-35 119.6 0.5 1.2e-34 118.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Sugar_tr PF00083.24 OAG15639.1 - 1.4e-74 251.6 9.7 1.7e-74 251.4 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15639.1 - 4.4e-36 124.5 11.8 2.5e-32 112.2 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG15639.1 - 1.5e-05 23.8 6.6 0.00021 20.0 1.1 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 OAG15639.1 - 0.00028 19.8 1.3 0.00057 18.8 1.3 1.5 1 0 0 1 1 1 1 LacY proton/sugar symporter TRI12 PF06609.13 OAG15639.1 - 0.046 12.1 4.1 0.018 13.4 1.4 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_1 PF05106.12 OAG15639.1 - 0.062 13.7 2.4 0.12 12.8 0.4 2.5 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Hema_HEFG PF02710.14 OAG15639.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Zn_clus PF00172.18 OAG15640.1 - 2.7e-08 33.8 14.1 4.2e-08 33.2 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5480 PF17576.2 OAG15640.1 - 0.14 12.2 0.2 5 7.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5480) MFS_1 PF07690.16 OAG15641.1 - 1.7e-32 112.7 21.3 1.7e-32 112.7 21.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15641.1 - 1.4e-14 53.8 10.4 1.4e-14 53.8 10.4 2.5 1 1 2 3 3 3 1 Sugar (and other) transporter Iso_dh PF00180.20 OAG15642.1 - 2.7e-88 296.4 0.0 3.1e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ECD PF18432.1 OAG15642.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Extracellular Cadherin domain Fungal_trans PF04082.18 OAG15643.1 - 8.5e-20 70.9 1.4 2.5e-19 69.3 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG15644.1 - 1.2e-21 76.9 0.1 2.1e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15644.1 - 8.6e-08 32.2 9.2 1.8e-07 31.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAG15645.1 - 2.3e-29 101.4 2.7 2.3e-29 101.4 2.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15645.1 - 2.5e-20 72.8 0.3 3.8e-20 72.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG15645.1 - 2.1e-13 50.3 0.0 3.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAG15645.1 - 0.0014 18.0 0.7 0.0045 16.3 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG15645.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG15645.1 - 0.013 15.5 0.1 0.054 13.5 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 OAG15645.1 - 0.017 16.2 0.0 0.049 14.7 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG15645.1 - 0.02 14.2 1.4 0.029 13.7 1.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG15645.1 - 0.048 12.9 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG15645.1 - 0.059 13.0 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 OAG15645.1 - 0.083 13.3 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 OAG15645.1 - 0.14 10.8 1.1 0.19 10.4 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.24 OAG15646.1 - 2.1e-95 320.3 26.7 2.4e-95 320.1 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15646.1 - 8.2e-33 113.8 54.9 1.1e-29 103.5 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG15646.1 - 0.00089 17.8 10.4 0.071 11.5 5.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 OAG15646.1 - 0.00089 17.9 3.7 0.00089 17.9 3.7 2.9 4 0 0 4 4 4 2 MFS/sugar transport protein SPT_ssu-like PF11779.8 OAG15646.1 - 0.068 12.8 2.4 0.23 11.1 2.4 1.9 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Fungal_trans PF04082.18 OAG15647.1 - 9.4e-18 64.2 1.2 1.5e-17 63.6 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG15647.1 - 6.1e-07 29.6 16.5 0.00025 21.3 7.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG15647.1 - 0.0014 19.3 12.2 0.066 14.1 5.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG15647.1 - 0.017 15.5 1.8 0.017 15.5 1.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG15647.1 - 0.21 11.9 3.6 0.57 10.5 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG15647.1 - 4.2 7.5 8.7 0.61 10.2 4.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short_C2 PF13561.6 OAG15648.1 - 4.9e-60 203.0 0.1 6.2e-60 202.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15648.1 - 2.6e-43 147.8 0.1 3.1e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG15648.1 - 1.3e-08 34.9 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 OAG15648.1 - 0.00089 18.7 4.1 0.069 12.5 1.3 2.9 2 1 1 3 3 3 2 ThiF family Polysacc_synt_2 PF02719.15 OAG15648.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase PF01425.21 OAG15649.1 - 7.7e-93 311.9 0.1 9.7e-93 311.6 0.1 1.1 1 0 0 1 1 1 1 Amidase ADH_N PF08240.12 OAG15650.1 - 2.7e-24 85.1 0.4 8.8e-24 83.5 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15650.1 - 4.3e-15 55.9 0.1 1e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase XdhC_C PF13478.6 OAG15650.1 - 0.16 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Polysacc_deac_1 PF01522.21 OAG15651.1 - 2e-18 66.5 0.0 4.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG15651.1 - 2.9e-05 23.8 0.1 0.00011 22.0 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 OAG15651.1 - 0.1 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Aa_trans PF01490.18 OAG15652.1 - 3.8e-31 108.2 28.3 4.5e-31 108.0 28.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FMO-like PF00743.19 OAG15653.1 - 3.5e-40 137.9 0.0 9.5e-30 103.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG15653.1 - 3.9e-16 59.2 0.0 3.4e-14 52.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG15653.1 - 3.3e-14 52.8 0.0 4.7e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG15653.1 - 7.1e-13 48.4 0.0 1.4e-12 47.5 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG15653.1 - 7.5e-06 26.0 0.0 4.2e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG15653.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG15653.1 - 0.0055 16.3 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG15653.1 - 0.087 12.1 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAG15653.1 - 0.1 12.7 0.0 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG15653.1 - 0.17 12.4 0.0 18 5.9 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAG15653.1 - 0.36 10.0 1.3 11 5.1 0.8 2.3 1 1 1 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 OAG15654.1 - 2.9e-05 23.5 0.3 0.00047 19.6 0.1 2.4 1 1 2 3 3 3 1 Flavin containing amine oxidoreductase PHO4 PF01384.20 OAG15656.1 - 0.0085 15.2 0.0 0.017 14.2 0.0 1.7 1 1 0 1 1 1 1 Phosphate transporter family Choline_transpo PF04515.12 OAG15656.1 - 0.019 14.2 0.4 0.041 13.1 0.4 1.5 1 0 0 1 1 1 0 Plasma-membrane choline transporter zf-rbx1 PF12678.7 OAG15657.1 - 2.9e-10 40.3 1.8 2.9e-10 40.3 1.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG15657.1 - 4.5e-09 36.0 0.5 4.5e-09 36.0 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG15657.1 - 6.5e-09 36.0 2.4 6.5e-09 36.0 2.4 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAG15657.1 - 1.4e-07 31.3 0.7 1.4e-07 31.3 0.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG15657.1 - 8.8e-06 25.5 7.0 5.6e-05 22.9 6.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG15657.1 - 3.6e-05 23.6 6.1 7.6e-05 22.6 1.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG15657.1 - 6.2e-05 22.8 0.2 6.2e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG15657.1 - 6.2e-05 23.0 1.8 0.00028 20.9 0.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAG15657.1 - 0.00011 22.2 0.5 0.00011 22.2 0.5 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-Nse PF11789.8 OAG15657.1 - 0.00021 21.0 1.0 0.015 15.1 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OAG15657.1 - 0.0051 16.9 1.2 0.0051 16.9 1.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OAG15657.1 - 0.0066 16.2 2.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 OAG15657.1 - 0.02 14.5 0.2 0.02 14.5 0.2 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 OAG15657.1 - 0.06 13.0 0.3 0.06 13.0 0.3 2.2 2 0 0 2 2 2 0 P-11 zinc finger Colicin_V PF02674.16 OAG15658.1 - 0.031 14.2 1.2 0.031 14.2 1.2 2.6 2 1 0 2 2 2 0 Colicin V production protein DUF2231 PF09990.9 OAG15658.1 - 2 8.9 9.1 0.46 10.9 2.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF4407 PF14362.6 OAG15660.1 - 0.046 13.1 7.4 0.077 12.3 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OAG15660.1 - 0.3 9.0 6.2 0.4 8.5 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 OAG15660.1 - 1 9.4 4.2 13 5.8 3.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 OAG15660.1 - 4.7 7.3 11.7 9.6 6.3 11.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OAG15660.1 - 6.4 5.8 13.5 12 4.9 13.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 OAG15660.1 - 9.5 5.7 11.1 18 4.8 11.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mut7-C PF01927.16 OAG15661.1 - 0.0051 16.9 1.3 0.0051 16.9 1.3 1.9 1 1 1 2 2 2 1 Mut7-C RNAse domain Zn_ribbon_SprT PF17283.2 OAG15661.1 - 2.4 8.1 6.7 3.2 7.7 5.3 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain LIM PF00412.22 OAG15661.1 - 3.3 8.0 9.6 9.5 6.5 9.6 1.8 1 1 0 1 1 1 0 LIM domain zf-Di19 PF05605.12 OAG15661.1 - 8.7 6.7 10.7 3.9 7.8 4.8 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MRC1 PF09444.10 OAG15662.1 - 1.3e-32 113.3 25.0 1.3e-32 113.3 25.0 8.1 6 3 1 9 9 9 2 MRC1-like domain COQ7 PF03232.13 OAG15663.1 - 6e-69 231.2 0.3 7.4e-69 230.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 OAG15663.1 - 2.6e-06 27.9 0.0 4.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF4455 PF14643.6 OAG15663.1 - 0.051 12.2 0.2 0.071 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Plus-3 PF03126.18 OAG15664.1 - 4.3e-23 81.9 0.0 1.3e-22 80.4 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain DDHD PF02862.17 OAG15664.1 - 9.8 6.3 15.5 8.3 6.5 0.5 2.2 2 0 0 2 2 2 0 DDHD domain Oxysterol_BP PF01237.18 OAG15665.1 - 2.3e-116 388.7 0.0 4.3e-116 387.8 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAG15665.1 - 4.4e-39 132.6 1.1 6.2e-39 132.2 0.2 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OAG15665.1 - 4.1e-06 27.2 0.5 1.9e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OAG15665.1 - 0.17 12.3 1.8 6.3 7.3 0.6 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain Lipase_GDSL PF00657.22 OAG15667.1 - 8e-07 29.2 0.1 9.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG15667.1 - 4.4e-05 24.0 2.8 7.9e-05 23.1 2.8 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TPR_12 PF13424.6 OAG15668.1 - 3.1e-13 49.8 16.6 0.1 12.9 0.1 8.6 7 1 1 9 9 8 4 Tetratricopeptide repeat NACHT PF05729.12 OAG15668.1 - 5.4e-08 32.9 0.5 5.7e-07 29.6 0.1 3.1 2 1 0 2 2 1 1 NACHT domain AAA_16 PF13191.6 OAG15668.1 - 1.8e-05 25.2 0.0 1.8e-05 25.2 0.0 2.9 4 0 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG15668.1 - 4.4e-05 23.8 0.5 0.00076 19.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OAG15668.1 - 0.0031 17.3 0.3 0.055 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 OAG15668.1 - 0.0044 16.9 14.3 4.6 7.5 0.0 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat PRK PF00485.18 OAG15668.1 - 0.014 15.1 0.3 0.33 10.7 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 OAG15668.1 - 0.026 15.0 4.9 0.071 13.5 0.0 4.0 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAG15668.1 - 0.029 14.1 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OAG15668.1 - 0.054 13.6 0.6 1.6 8.8 0.0 3.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAG15668.1 - 0.079 12.7 0.1 0.55 9.9 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OAG15668.1 - 0.083 12.8 0.1 0.3 11.0 0.1 2.0 1 0 0 1 1 1 0 NTPase DUF5123 PF17161.4 OAG15668.1 - 0.13 13.3 1.4 0.74 10.9 0.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) AAA_23 PF13476.6 OAG15668.1 - 0.3 11.5 0.0 0.3 11.5 0.0 4.1 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAG15668.1 - 0.4 10.7 0.0 0.4 10.7 0.0 5.5 5 1 1 6 6 6 0 Helicase HerA, central domain ABC_tran PF00005.27 OAG15668.1 - 0.71 10.4 0.0 0.71 10.4 0.0 2.7 3 0 0 3 3 3 0 ABC transporter TPR_8 PF13181.6 OAG15668.1 - 3.6 8.0 9.3 50 4.5 0.2 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Aldolase_II PF00596.21 OAG15669.1 - 4.1e-47 160.5 0.0 5.3e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain His_Phos_1 PF00300.22 OAG15670.1 - 8.6e-05 22.3 0.3 0.13 11.9 0.1 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) YrpD PF15493.6 OAG15670.1 - 0.14 12.0 0.9 0.22 11.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD TFIIA PF03153.13 OAG15670.1 - 0.19 11.7 3.5 0.13 12.2 0.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Vps36_ESCRT-II PF11605.8 OAG15671.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 OAG15671.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Totivirus_coat PF05518.11 OAG15671.1 - 2.5 6.1 4.1 3.5 5.5 4.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Thiolase_N PF00108.23 OAG15672.1 - 1.8e-73 247.1 4.6 1.8e-73 247.1 4.6 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG15672.1 - 7.1e-45 151.6 0.5 1.5e-44 150.6 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG15672.1 - 0.031 13.8 3.3 0.31 10.6 1.7 2.8 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG15672.1 - 0.036 13.9 0.6 12 5.8 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4129 PF13559.6 OAG15673.1 - 0.002 18.3 0.3 0.0055 16.9 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) AgrB PF04647.15 OAG15673.1 - 0.038 13.3 3.0 0.061 12.6 3.0 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Mannosyl_trans2 PF04188.13 OAG15673.1 - 0.067 12.5 1.0 0.089 12.1 0.3 1.4 2 0 0 2 2 2 0 Mannosyltransferase (PIG-V) SelP_N PF04592.14 OAG15673.1 - 0.23 10.8 4.6 0.44 9.9 4.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RuvC_III PF18541.1 OAG15673.1 - 0.32 10.9 2.5 0.54 10.2 2.5 1.4 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 TBP PF00352.21 OAG15674.1 - 1.6e-66 220.2 0.1 6.3e-32 109.4 0.1 2.4 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAG15674.1 - 0.00014 21.9 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAG15674.1 - 0.17 11.8 0.1 0.76 9.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) p450 PF00067.22 OAG15675.1 - 8e-49 166.6 0.0 1.2e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG15676.1 - 2e-37 128.9 34.8 2.9e-37 128.4 34.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG15676.1 - 9e-10 37.6 14.6 1.2e-09 37.2 14.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG15676.1 - 1.1e-07 31.1 11.3 1.1e-07 31.1 11.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter zf-RING_2 PF13639.6 OAG15677.1 - 4.9e-08 33.2 6.0 1.7e-07 31.5 6.0 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG15677.1 - 3.7e-06 27.1 6.4 6.2e-06 26.4 6.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG15677.1 - 5.3e-06 26.2 3.9 1.7e-05 24.6 3.9 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAG15677.1 - 2.8e-05 24.1 4.2 6.8e-05 22.8 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG15677.1 - 0.0002 21.2 2.6 0.0002 21.2 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG15677.1 - 0.00027 20.9 3.6 0.00047 20.1 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG15677.1 - 0.0028 17.5 5.0 0.005 16.7 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OAG15677.1 - 0.012 15.3 1.3 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 OAG15677.1 - 0.015 15.1 6.1 0.11 12.4 6.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG15677.1 - 0.027 14.1 4.2 0.027 14.1 4.2 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAG15677.1 - 0.035 13.8 4.0 4.4 7.1 4.0 2.6 1 1 0 1 1 1 0 RING-like zinc finger zf-LITAF-like PF10601.9 OAG15677.1 - 0.19 12.0 4.6 0.75 10.1 4.6 1.9 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-ANAPC11 PF12861.7 OAG15677.1 - 0.22 11.6 3.2 0.42 10.7 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAG15677.1 - 0.41 10.8 3.3 1.4 9.1 3.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Peptidase_S10 PF00450.22 OAG15678.1 - 2.6e-71 241.3 0.0 3.4e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Prenyltransf PF01255.19 OAG15680.1 - 2.5e-82 275.7 0.2 4e-82 275.1 0.2 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_S64 PF08192.11 OAG15681.1 - 0.037 12.5 0.0 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 SKA2 PF16740.5 OAG15681.1 - 0.08 12.7 0.4 1.4 8.7 0.0 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3053 PF11254.8 OAG15681.1 - 0.093 12.3 0.7 0.15 11.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) NigD_C PF17415.2 OAG15681.1 - 0.15 12.1 0.1 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain Sld5 PF05916.11 OAG15682.1 - 3.2e-22 79.1 0.0 4.9e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Phage_spike PF18715.1 OAG15682.1 - 0.24 11.5 0.6 0.38 10.9 0.0 1.5 2 0 0 2 2 2 0 Phage spike trimer BLM10_mid PF16507.5 OAG15683.1 - 1.8e-206 686.9 0.0 2.1e-205 683.4 0.0 2.2 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAG15683.1 - 1.2e-30 105.3 0.2 1.7e-29 101.5 0.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAG15683.1 - 1.3e-21 76.6 0.0 4e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal IFRD PF05004.13 OAG15683.1 - 0.012 14.7 0.0 0.53 9.3 0.0 2.9 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 OAG15683.1 - 0.023 14.9 0.0 5.2 7.6 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.8 OAG15683.1 - 0.056 13.0 0.6 5.2 6.5 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal OCD_Mu_crystall PF02423.15 OAG15684.1 - 5.3e-09 35.5 1.2 4.3e-05 22.6 0.0 3.3 3 2 1 4 4 4 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG15684.1 - 0.00063 19.8 0.0 0.021 14.9 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DUF3530 PF12048.8 OAG15684.1 - 0.0049 16.3 0.2 0.24 10.8 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3530) Ribosomal_L7Ae PF01248.26 OAG15685.1 - 2.1e-22 78.6 1.1 3.6e-22 77.9 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAG15685.1 - 0.014 15.5 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Mannosyl_trans2 PF04188.13 OAG15686.1 - 2.7e-58 198.3 13.9 3.8e-58 197.9 13.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Drf_GBD PF06371.13 OAG15688.1 - 6e-10 39.0 3.4 4e-09 36.3 3.4 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain BRAP2 PF07576.12 OAG15689.1 - 2.5e-34 117.4 0.0 4.2e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAG15689.1 - 1e-19 70.6 5.3 2.6e-19 69.3 5.3 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAG15689.1 - 2.9e-08 33.9 8.8 2.9e-08 33.9 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG15689.1 - 6.4e-06 25.9 8.2 6.4e-06 25.9 8.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG15689.1 - 6.2e-05 22.8 7.3 6.2e-05 22.8 7.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG15689.1 - 0.00012 22.0 4.7 0.00082 19.4 4.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG15689.1 - 0.00019 21.7 6.0 0.00054 20.2 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG15689.1 - 0.00038 20.1 4.9 0.00038 20.1 4.9 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAG15689.1 - 0.00074 19.3 15.6 0.00089 19.1 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAG15689.1 - 0.0012 18.6 1.9 0.003 17.4 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OAG15689.1 - 0.0027 17.6 6.5 0.0027 17.6 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAG15689.1 - 0.01 15.9 4.0 0.026 14.6 4.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tropomyosin_1 PF12718.7 OAG15689.1 - 0.08 13.1 22.6 0.16 12.1 22.6 1.5 1 0 0 1 1 1 0 Tropomyosin like TMF_DNA_bd PF12329.8 OAG15689.1 - 0.17 11.9 21.6 0.24 11.4 5.9 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 OAG15689.1 - 0.32 11.3 4.0 2.3 8.5 4.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 OAG15689.1 - 0.53 10.8 10.8 0.14 12.6 1.1 2.3 2 0 0 2 2 2 0 PhoU domain TPR_MLP1_2 PF07926.12 OAG15689.1 - 0.57 10.2 28.7 1.1 9.4 28.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.6 OAG15689.1 - 0.85 9.5 18.3 0.2 11.6 8.6 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 ATG16 PF08614.11 OAG15689.1 - 0.99 9.6 26.4 16 5.7 26.5 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 OAG15689.1 - 1.6 8.1 11.1 2.8 7.2 11.1 1.3 1 0 0 1 1 1 0 FAM76 protein AAA_13 PF13166.6 OAG15689.1 - 1.6 7.3 15.2 2.2 6.8 15.2 1.1 1 0 0 1 1 1 0 AAA domain T3SSipB PF16535.5 OAG15689.1 - 1.6 9.2 25.2 1.6 9.2 5.2 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB Fib_alpha PF08702.10 OAG15689.1 - 1.9 8.7 11.7 2.1 8.5 9.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Zn_ribbon_17 PF17120.5 OAG15689.1 - 2.2 7.9 13.7 0.09 12.4 5.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type AAA_23 PF13476.6 OAG15689.1 - 2.4 8.6 10.0 4.4 7.8 10.0 1.4 1 0 0 1 1 1 0 AAA domain Sec20 PF03908.13 OAG15689.1 - 4.1 7.4 7.9 4.2 7.3 0.6 2.4 2 0 0 2 2 2 0 Sec20 DUF1664 PF07889.12 OAG15689.1 - 5.1 7.1 11.4 3.9 7.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OAG15689.1 - 5.4 7.4 15.3 8.7 6.7 10.0 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 OAG15689.1 - 6.5 6.2 12.7 11 5.5 12.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 OAG15689.1 - 6.9 6.5 7.9 15 5.5 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ZapB PF06005.12 OAG15689.1 - 6.9 7.2 21.5 2.2 8.8 8.3 2.7 2 1 1 3 3 2 0 Cell division protein ZapB FUSC PF04632.12 OAG15689.1 - 7 5.1 10.0 11 4.4 10.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 OAG15689.1 - 7.8 5.3 7.0 11 4.8 7.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 OAG15690.1 - 1.9e-39 132.9 18.4 7.1e-05 23.5 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 OAG15690.1 - 1.3e-10 41.0 0.1 2.3e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAG15690.1 - 3e-08 33.8 1.7 0.079 13.3 0.0 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 OAG15690.1 - 2.6e-07 30.3 0.1 5.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAG15690.1 - 2.4e-05 23.2 1.7 2.1 6.9 0.0 5.2 4 1 1 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OAG15690.1 - 0.0002 21.0 1.1 0.091 12.3 0.7 2.9 1 1 0 1 1 1 1 PQQ-like domain F-box_4 PF15966.5 OAG15690.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box Acetyltransf_2 PF00797.17 OAG15693.1 - 5.3e-38 131.2 0.0 7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Endonuc-dimeris PF09124.10 OAG15693.1 - 0.0061 16.7 0.5 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 T4 recombination endonuclease VII, dimerisation HTH_33 PF13592.6 OAG15693.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix MWFE PF15879.5 OAG15694.1 - 4.3e-23 81.2 0.1 5.3e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 OAG15695.1 - 4.9e-75 251.1 0.0 7.5e-75 250.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG15695.1 - 1.9e-19 69.0 3.0 4.2e-19 67.9 3.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 OAG15695.1 - 3.1e-09 36.8 4.9 3.1e-09 36.8 4.9 2.0 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.20 OAG15695.1 - 0.079 12.7 0.7 0.17 11.6 0.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Acetyltransf_7 PF13508.7 OAG15695.1 - 0.19 12.1 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD PF00628.29 OAG15695.1 - 0.47 10.4 9.6 0.24 11.3 5.8 2.3 2 0 0 2 2 2 0 PHD-finger zinc_ribbon_10 PF10058.9 OAG15695.1 - 1.5 8.6 4.4 2.4 8.0 0.1 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Glyco_hydro_43 PF04616.14 OAG15696.1 - 1.6e-65 221.3 4.2 2.1e-65 220.9 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG15696.1 - 3.2e-17 62.9 0.0 6.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain p450 PF00067.22 OAG15697.1 - 5.6e-47 160.5 0.0 7.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Velvet PF11754.8 OAG15698.1 - 1.4e-38 133.3 1.3 1.8e-27 96.9 0.3 2.2 1 1 1 2 2 2 2 Velvet factor HSP70 PF00012.20 OAG15700.1 - 5.7e-09 34.7 0.0 1.8e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein GrpE PF01025.19 OAG15701.1 - 0.03 14.0 1.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 GrpE FH2 PF02181.23 OAG15701.1 - 0.059 12.5 0.3 0.092 11.9 0.3 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain CDC45 PF02724.14 OAG15702.1 - 1.2e-238 793.6 0.1 2.9e-238 792.4 0.1 2.1 1 1 0 1 1 1 1 CDC45-like protein Bestrophin PF01062.21 OAG15702.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel CSRNP_N PF16019.5 OAG15702.1 - 2 8.3 6.4 0.61 10.0 1.7 2.3 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus BUD22 PF09073.10 OAG15702.1 - 4.3 6.6 32.4 0.58 9.4 10.5 2.4 2 0 0 2 2 2 0 BUD22 FAM60A PF15396.6 OAG15702.1 - 5.5 6.9 7.8 0.28 11.2 1.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 OAG15702.1 - 5.9 6.6 10.5 1.2 8.9 2.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Acyltransferase PF01553.21 OAG15703.1 - 4e-11 42.7 0.0 8.3e-10 38.4 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase BMP2K_C PF15282.6 OAG15703.1 - 0.066 13.1 2.0 0.11 12.3 2.0 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Glyco_hydro_76 PF03663.14 OAG15704.1 - 2.8e-132 441.7 15.5 3.7e-132 441.3 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG15704.1 - 0.032 13.3 11.5 0.31 10.1 1.2 2.6 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Ccdc124 PF06244.12 OAG15705.1 - 7.4e-27 94.4 24.4 7.4e-27 94.4 24.4 2.6 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 FLYWCH_u PF16662.5 OAG15705.1 - 0.052 13.6 1.4 0.094 12.8 0.1 2.3 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 AHJR-like PF18743.1 OAG15705.1 - 0.82 9.2 5.5 0.26 10.8 0.3 2.5 2 2 1 3 3 3 0 REase_AHJR-like TMEM214 PF10151.9 OAG15705.1 - 1.6 7.1 13.5 2.8 6.3 13.5 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator LicD PF04991.13 OAG15705.1 - 8 6.5 10.1 0.52 10.4 0.9 2.0 2 0 0 2 2 2 0 LicD family GGDEF PF00990.21 OAG15706.1 - 0.063 13.0 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain Spectrin PF00435.21 OAG15706.1 - 0.26 11.8 6.3 0.57 10.7 6.0 1.9 1 1 0 1 1 1 0 Spectrin repeat FXR_C1 PF16096.5 OAG15706.1 - 0.94 9.7 10.3 0.077 13.2 4.4 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 MIP PF00230.20 OAG15707.1 - 4.4e-50 170.5 2.9 5.5e-50 170.2 2.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein OPT PF03169.15 OAG15708.1 - 2.1e-156 522.1 19.3 2.4e-156 521.9 19.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 OAG15708.1 - 0.0057 16.6 0.9 0.11 12.5 0.0 3.0 2 0 0 2 2 2 1 Bacteriophage P21 holin S MscL PF01741.18 OAG15708.1 - 0.63 10.3 3.9 5.1 7.4 0.1 3.1 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL DUF4212 PF13937.6 OAG15708.1 - 0.97 9.9 0.0 0.97 9.9 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4212) Peptidase_C13 PF01650.18 OAG15709.1 - 1.3e-41 142.8 0.1 1.8e-41 142.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family PARP PF00644.20 OAG15710.1 - 2.1e-08 34.0 0.1 4.4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 OAG15710.1 - 2.5e-07 30.5 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG15710.1 - 0.12 12.7 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 RWD domain COG5 PF10392.9 OAG15711.1 - 0.0027 17.9 0.1 0.0055 16.9 0.1 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2040 PF09745.9 OAG15711.1 - 0.0063 16.6 1.9 0.2 11.7 1.4 2.3 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DEDD_Tnp_IS110 PF01548.17 OAG15711.1 - 0.013 15.4 0.2 0.027 14.3 0.2 1.5 1 0 0 1 1 1 0 Transposase COG7 PF10191.9 OAG15711.1 - 0.13 10.5 0.0 1.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) DUF2076 PF09849.9 OAG15711.1 - 9.3 6.2 11.1 0.4 10.7 5.5 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) BIR PF00653.21 OAG15712.1 - 3.5e-45 152.5 0.7 2.2e-21 76.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DBP PF12361.8 OAG15712.1 - 0.23 11.3 5.1 0.38 10.6 5.1 1.2 1 0 0 1 1 1 0 Duffy-antigen binding protein Tam41_Mmp37 PF09139.11 OAG15713.1 - 1.2e-119 399.5 0.0 1.4e-119 399.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF2856 PF11043.8 OAG15713.1 - 0.01 16.0 0.1 0.029 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2856) AT_hook PF02178.19 OAG15714.1 - 0.001 18.7 14.9 0.24 11.4 2.5 3.7 2 0 0 2 2 2 2 AT hook motif GEN1_C PF18380.1 OAG15715.1 - 1.5e-28 99.7 0.1 1.5e-28 99.7 0.1 2.3 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 OAG15715.1 - 4.4e-23 81.4 0.0 7.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG15715.1 - 1.1e-09 38.7 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OAG15715.1 - 0.009 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Apo-CIII PF05778.12 OAG15716.1 - 0.043 13.4 1.6 2.1 8.1 0.1 3.7 4 0 0 4 4 4 0 Apolipoprotein CIII (Apo-CIII) AAA PF00004.29 OAG15717.1 - 4.4e-19 69.2 0.0 1.1e-18 68.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG15717.1 - 3.6e-05 24.1 0.3 0.0006 20.1 0.0 2.8 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 OAG15717.1 - 8.4e-05 23.0 0.0 0.00032 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG15717.1 - 0.0032 17.5 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAG15717.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG15717.1 - 0.03 14.5 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG15717.1 - 0.031 14.4 0.0 0.083 13.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAG15717.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2459 PF09601.10 OAG15717.1 - 0.051 13.4 0.3 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) RNA_helicase PF00910.22 OAG15717.1 - 0.076 13.4 0.0 2.3 8.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 OAG15717.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 OAG15717.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG15717.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OAG15717.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AgI_II_C2 PF17998.1 OAG15717.1 - 0.69 10.2 4.9 0.29 11.4 0.1 2.7 4 0 0 4 4 3 0 Cell surface antigen I/II C2 terminal domain zf-RING_2 PF13639.6 OAG15720.1 - 4.6e-09 36.5 2.0 6.8e-09 35.9 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG15720.1 - 2.5e-06 27.7 3.6 2e-05 24.8 3.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG15720.1 - 0.00073 19.5 0.5 0.0011 18.9 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG15720.1 - 0.0012 18.6 4.2 0.0037 17.1 3.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG15720.1 - 0.0021 17.8 1.5 0.0034 17.1 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OAG15720.1 - 0.0033 17.4 5.0 0.0062 16.5 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG15720.1 - 0.022 14.7 1.1 0.036 13.9 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PUL PF08324.11 OAG15720.1 - 0.072 12.3 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 PUL domain NAD_binding_10 PF13460.6 OAG15721.1 - 1.3e-05 25.2 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 OAG15721.1 - 0.0045 17.1 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 OAG15721.1 - 0.044 13.2 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAG15722.1 - 0.048 12.7 1.1 0.64 9.0 0.4 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Inositol_P PF00459.25 OAG15724.1 - 2.5e-52 178.1 0.9 6.5e-52 176.7 0.9 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.13 OAG15725.1 - 7.9e-31 106.9 0.6 2.3e-23 82.7 0.2 2.4 1 1 1 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 OAG15725.1 - 4.7e-24 84.4 0.1 1.6e-23 82.7 0.1 2.0 1 0 0 1 1 1 1 Rsm1-like Methyltr_RsmB-F PF01189.17 OAG15726.1 - 6.7e-35 120.6 0.0 1.4e-26 93.4 0.0 3.5 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F B2-adapt-app_C PF09066.10 OAG15726.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain FtsJ PF01728.19 OAG15726.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L30_N PF08079.12 OAG15727.1 - 1.9e-19 69.7 16.1 1.9e-19 69.7 16.1 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAG15727.1 - 3.4e-18 65.2 2.0 3.4e-18 65.2 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 OAG15727.1 - 0.015 15.3 4.6 0.021 14.7 4.6 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tipalpha PF16753.5 OAG15727.1 - 0.033 14.0 0.4 0.056 13.3 0.2 1.6 1 1 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter DUF4337 PF14235.6 OAG15727.1 - 3.7 7.7 8.3 5.4 7.1 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fungal_trans PF04082.18 OAG15728.1 - 8.4e-24 84.0 0.0 2e-23 82.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15728.1 - 4.7e-09 36.2 10.4 7.3e-09 35.6 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spem1 PF15670.5 OAG15728.1 - 0.06 12.9 1.7 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 MFS_1 PF07690.16 OAG15730.1 - 8.5e-39 133.5 22.3 7.5e-31 107.3 0.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG15730.1 - 8.9e-11 41.3 0.2 8.9e-11 41.3 0.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG15730.1 - 0.00019 20.4 6.9 0.00056 18.9 6.9 1.9 1 1 0 1 1 1 1 MFS_1 like family Antimicrobial24 PF16049.5 OAG15730.1 - 6.1 6.9 10.5 15 5.7 0.6 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide UQ_con PF00179.26 OAG15732.1 - 5.7e-09 35.8 0.1 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG15732.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 RWD domain adh_short PF00106.25 OAG15735.1 - 2.4e-37 128.3 0.1 3.5e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15735.1 - 2.6e-24 86.1 0.1 3.7e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15735.1 - 1.5e-07 31.5 0.6 4.2e-07 30.1 0.6 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG15735.1 - 0.0011 18.5 0.1 0.0025 17.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG15735.1 - 0.0024 16.9 0.1 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 OAG15735.1 - 0.0027 17.1 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG15735.1 - 0.052 13.4 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding GTP1_OBG PF01018.22 OAG15736.1 - 3.4e-40 137.2 2.6 2e-29 102.2 3.8 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 OAG15736.1 - 1.3e-23 83.2 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG15736.1 - 1.1e-07 31.5 0.1 2.7e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 OAG15736.1 - 0.0088 15.1 0.0 0.79 8.7 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAG15736.1 - 0.014 15.9 0.0 0.04 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 OAG15736.1 - 0.019 14.4 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 OAG15736.1 - 0.12 12.5 0.0 13 5.9 0.0 2.3 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 OAG15736.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 OAG15736.1 - 0.16 11.5 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sugar_tr PF00083.24 OAG15737.1 - 3e-77 260.4 20.5 3.5e-77 260.2 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15737.1 - 2.4e-28 99.1 30.6 2.1e-26 92.7 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG15737.1 - 0.017 13.4 9.6 1.2 7.3 0.4 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 OAG15737.1 - 1.1 9.3 6.7 16 5.6 0.7 3.4 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB Carboxyl_trans PF01039.22 OAG15738.1 - 1.6e-78 264.6 0.0 1.9e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAG15739.1 - 1.8e-57 194.3 0.0 2.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAG15739.1 - 5.2e-33 113.4 0.0 1.4e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAG15739.1 - 3e-26 92.1 0.1 1e-25 90.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAG15739.1 - 7.2e-13 48.2 2.7 1e-12 47.7 1.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG15739.1 - 2.7e-07 30.4 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAG15739.1 - 6.6e-07 29.1 1.2 1.7e-06 27.7 0.1 2.3 2 1 0 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 OAG15739.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 OAG15739.1 - 0.00044 20.2 0.2 0.002 18.0 0.1 2.2 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 OAG15739.1 - 0.00086 19.4 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 OAG15739.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 OAG15739.1 - 0.019 14.9 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Hamartin PF04388.12 OAG15739.1 - 0.88 8.2 9.1 0.61 8.7 6.6 1.8 2 0 0 2 2 2 0 Hamartin protein OsmC PF02566.19 OAG15740.1 - 2.2e-14 53.7 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein p450 PF00067.22 OAG15741.1 - 3.2e-45 154.8 0.0 5.6e-45 153.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exo1 PF01612.20 OAG15742.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Ribosomal_L13e PF01294.18 OAG15742.1 - 0.74 9.6 3.7 1.5 8.7 3.7 1.4 1 0 0 1 1 1 0 Ribosomal protein L13e DUF21 PF01595.20 OAG15743.1 - 3.2e-32 111.6 0.1 5.8e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAG15743.1 - 8.4e-06 26.1 0.2 0.086 13.3 0.0 3.0 2 0 0 2 2 2 2 CBS domain Transket_pyr PF02779.24 OAG15744.1 - 2e-42 144.9 0.0 3.2e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG15744.1 - 2.2e-34 118.0 0.3 9.6e-34 115.9 0.2 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OAG15744.1 - 0.0007 19.9 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II VIT PF08487.10 OAG15745.1 - 2.2e-32 111.6 0.2 6.1e-32 110.1 0.2 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OAG15745.1 - 1.5e-27 96.5 0.0 3.1e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 OAG15745.1 - 1.7e-13 50.3 0.1 3.9e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OAG15745.1 - 5.3e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG15745.1 - 1.2e-08 35.5 0.0 5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OAG15745.1 - 0.00013 21.4 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein RNA_pol_Rpb1_R PF05001.13 OAG15745.1 - 0.1 13.0 12.3 0.45 11.0 12.3 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat MRAP PF15183.6 OAG15746.1 - 0.034 14.1 0.4 0.28 11.1 0.3 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DHHC PF01529.20 OAG15746.1 - 0.27 11.3 3.8 0.25 11.5 1.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase STE3 PF02076.15 OAG15746.1 - 0.77 8.9 8.4 0.44 9.7 6.1 1.8 1 1 1 2 2 2 0 Pheromone A receptor SPK PF04435.18 OAG15747.1 - 0.014 15.8 0.6 0.034 14.5 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF545) F_bP_aldolase PF01116.20 OAG15748.1 - 1.6e-73 247.6 0.3 1.8e-73 247.5 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II GARP PF16731.5 OAG15748.1 - 0.13 11.9 0.3 0.22 11.2 0.0 1.4 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Fungal_trans_2 PF11951.8 OAG15749.1 - 3.1e-08 32.8 0.0 1.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15749.1 - 6.1e-06 26.3 10.3 6.1e-06 26.3 10.3 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG15750.1 - 8e-51 172.8 0.0 1.1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15750.1 - 3.9e-45 153.7 0.1 4.7e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG15750.1 - 1.6e-09 37.9 0.2 2.9e-09 37.1 0.2 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG15750.1 - 0.0054 15.9 0.0 0.0066 15.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG15750.1 - 0.0097 14.9 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG15750.1 - 0.14 11.6 0.2 0.36 10.2 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 OAG15751.1 - 1.2e-39 136.2 32.9 1.2e-39 136.2 32.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FGGY_N PF00370.21 OAG15751.1 - 0.032 13.8 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain BUD22 PF09073.10 OAG15754.1 - 1.6e-78 265.0 45.8 2e-78 264.7 45.8 1.1 1 0 0 1 1 1 1 BUD22 DUF1858 PF08984.11 OAG15754.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) T3SS_needle_E PF08988.10 OAG15754.1 - 0.24 11.6 3.1 0.72 10.1 3.1 1.8 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DUF5082 PF16888.5 OAG15756.1 - 0.073 13.4 0.6 0.25 11.7 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4455 PF14643.6 OAG15756.1 - 0.077 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF2076 PF09849.9 OAG15756.1 - 5.7 6.9 41.4 1.7 8.6 19.8 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Myc_target_1 PF15179.6 OAG15757.1 - 0.0012 18.8 0.9 0.73 9.7 0.1 2.2 2 0 0 2 2 2 2 Myc target protein 1 Heliorhodopsin PF18761.1 OAG15757.1 - 0.019 14.3 0.2 0.043 13.1 0.2 1.6 1 0 0 1 1 1 0 Heliorhodopsin TMEM190 PF15431.6 OAG15757.1 - 0.019 15.1 3.5 2 8.6 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 190 DUF3522 PF12036.8 OAG15757.1 - 0.028 14.7 2.5 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) FtsX PF02687.21 OAG15757.1 - 0.37 11.3 7.5 0.13 12.8 0.8 2.5 3 0 0 3 3 3 0 FtsX-like permease family DUF4010 PF13194.6 OAG15757.1 - 1.2 8.7 6.9 0.23 11.1 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) GMC_oxred_N PF00732.19 OAG15758.1 - 8.1e-56 189.6 0.0 1.3e-55 188.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG15758.1 - 3.5e-28 98.9 0.0 6.9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG15758.1 - 1.9e-05 24.0 0.5 0.018 14.1 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG15758.1 - 4.1e-05 23.7 0.2 0.00012 22.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG15758.1 - 0.00067 19.0 0.2 0.0027 17.0 0.3 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG15758.1 - 0.0017 18.0 0.3 0.028 14.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG15758.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG15758.1 - 0.0067 15.7 0.1 0.096 11.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG15758.1 - 0.0071 15.6 0.1 1.2 8.3 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG15758.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding CoA_binding_3 PF13727.6 OAG15758.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain HI0933_like PF03486.14 OAG15758.1 - 0.23 10.1 0.6 0.35 9.5 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.21 OAG15759.1 - 4.3e-128 427.9 42.5 4.9e-128 427.7 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG15759.1 - 2.6e-39 135.3 50.2 3.2e-39 135.0 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 OAG15760.1 - 1.6e-36 125.8 0.1 2.6e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CEND1 PF15677.5 OAG15761.1 - 0.0029 18.2 6.4 0.0029 18.2 6.4 2.6 2 1 1 3 3 3 1 Cell cycle exit and neuronal differentiation protein 1 Alpha_GJ PF03229.13 OAG15761.1 - 0.033 14.8 3.6 0.033 14.8 3.6 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4366 PF14283.6 OAG15761.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1218 PF06749.12 OAG15762.1 - 1.6 9.3 6.6 0.33 11.5 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CHRD PF07452.12 OAG15763.1 - 3.2e-11 44.2 0.2 5.3e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 CHRD domain Peroxidase_2 PF01328.17 OAG15764.1 - 2.2e-44 152.2 0.0 3e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_92 PF07971.12 OAG15766.1 - 4.1e-135 451.3 1.4 5e-135 451.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG15766.1 - 5e-52 177.2 4.0 7.3e-52 176.6 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TMEM61 PF15105.6 OAG15767.1 - 4.2 7.1 5.8 6.3 6.6 5.8 1.2 1 0 0 1 1 1 0 TMEM61 protein family YrhK PF14145.6 OAG15769.1 - 0.00025 20.9 21.0 0.011 15.6 2.0 4.3 4 0 0 4 4 4 4 YrhK-like protein DUF202 PF02656.15 OAG15769.1 - 0.78 10.2 8.8 2.4 8.7 0.7 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ComJ PF11033.8 OAG15770.1 - 0.041 13.6 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) DUF3487 PF11990.8 OAG15770.1 - 6.5 6.7 15.0 2.5 8.0 2.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) ThrE PF06738.12 OAG15772.1 - 2e-66 223.8 0.9 2e-66 223.8 0.9 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAG15772.1 - 2.8e-05 24.2 1.3 2.8e-05 24.2 1.3 3.6 4 0 0 4 4 4 2 Threonine/Serine exporter, ThrE FAD_binding_3 PF01494.19 OAG15774.1 - 1.6e-41 142.7 0.0 2.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG15774.1 - 2e-06 27.3 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG15774.1 - 7.6e-06 25.7 0.1 0.015 14.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG15774.1 - 9.4e-06 25.8 0.1 2.1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG15774.1 - 9.1e-05 22.9 0.0 0.03 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG15774.1 - 0.00013 21.3 0.1 0.00021 20.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG15774.1 - 0.0061 15.3 0.4 0.018 13.8 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG15774.1 - 0.011 14.8 0.3 0.021 13.9 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG15774.1 - 0.036 13.1 0.1 0.087 11.9 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG15774.1 - 0.055 13.5 0.2 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG15774.1 - 0.097 11.9 0.7 0.16 11.2 0.5 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.22 OAG15775.1 - 2.6e-102 343.3 1.0 3.1e-102 343.1 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MetallophosN PF16371.5 OAG15775.1 - 0.0097 16.1 0.6 1.1 9.6 0.1 2.8 2 0 0 2 2 2 2 N terminal of Calcineurin-like phosphoesterase Sugar_tr PF00083.24 OAG15776.1 - 2.8e-102 342.9 13.2 7.2e-83 278.9 3.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG15776.1 - 9.9e-12 44.4 33.5 2.7e-09 36.4 14.9 3.0 1 1 3 4 4 4 2 Major Facilitator Superfamily Complex1_LYR PF05347.15 OAG15778.1 - 0.12 12.4 0.3 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Spc7 PF08317.11 OAG15781.1 - 0.0005 19.0 23.3 0.0005 19.0 23.3 6.6 1 1 6 7 7 7 5 Spc7 kinetochore protein HOOK PF05622.12 OAG15781.1 - 4.1 5.4 106.5 0.31 9.1 18.7 3.2 2 1 0 2 2 2 0 HOOK protein VSP PF03302.13 OAG15782.1 - 0.0075 15.2 0.6 0.0092 14.9 0.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein zf-Nse PF11789.8 OAG15783.1 - 2.7e-22 78.3 0.5 4.6e-22 77.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OAG15783.1 - 5.7e-05 23.1 0.3 0.0001 22.2 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger ParD_antitoxin PF03693.14 OAG15783.1 - 0.0039 17.6 0.2 0.0083 16.5 0.2 1.5 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH zf-MIZ PF02891.20 OAG15783.1 - 0.0042 16.8 0.2 0.0084 15.8 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Fcf2 PF08698.11 OAG15783.1 - 0.0047 17.3 0.5 0.016 15.6 0.5 1.9 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing zf-C3HC4_2 PF13923.6 OAG15783.1 - 0.014 15.3 0.2 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 OAG15784.1 - 2.3e-52 174.9 5.9 5e-18 64.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TAP35_44 PF07265.11 OAG15784.1 - 0.03 14.4 1.5 0.41 10.7 0.3 2.2 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Serine_protease PF18405.1 OAG15784.1 - 0.037 13.2 2.6 0.14 11.2 1.5 2.5 1 1 0 1 1 1 0 Gammaproteobacterial serine protease F-actin_cap_A PF01267.17 OAG15785.1 - 6.3e-96 320.9 0.0 7.2e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF5024 PF16427.5 OAG15785.1 - 0.14 12.5 0.1 2.3 8.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5024) VHS PF00790.19 OAG15788.1 - 5.4e-25 87.9 0.0 1.2e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAG15788.1 - 9.3e-05 22.7 0.3 0.00022 21.5 0.3 1.6 1 0 0 1 1 1 1 GAT domain Shadoo PF14999.6 OAG15789.1 - 0.026 14.6 2.2 0.034 14.3 2.2 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective VIT1 PF01988.19 OAG15792.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 VIT family CorA PF01544.18 OAG15793.1 - 1.6e-06 27.6 0.2 2.7e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC_membrane PF00664.23 OAG15794.1 - 0.0043 16.7 0.0 0.0061 16.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4564 PF15169.6 OAG15794.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) DEAD PF00270.29 OAG15795.1 - 6.4e-41 140.0 0.0 1.2e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG15795.1 - 1.8e-27 95.9 0.0 4.5e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG15795.1 - 1.1e-05 25.5 0.6 0.0013 18.8 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit FtsJ PF01728.19 OAG15796.1 - 6.3e-64 215.3 0.0 9.3e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase KH_1 PF00013.29 OAG15798.1 - 4.3e-90 295.6 29.2 1.8e-13 50.1 0.0 13.1 13 1 0 13 13 13 9 KH domain SLS PF14611.6 OAG15798.1 - 2.3e-17 63.6 4.5 0.019 14.8 0.0 8.8 5 3 3 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 OAG15798.1 - 9.2e-12 44.6 13.2 0.074 12.9 0.1 7.5 7 0 0 7 7 7 5 KH domain KH_4 PF13083.6 OAG15798.1 - 0.00031 20.5 3.7 0.73 9.8 0.1 5.2 5 0 0 5 5 5 2 KH domain BMC PF00936.19 OAG15798.1 - 0.0018 18.3 1.6 2.2 8.3 0.0 3.4 3 0 0 3 3 3 2 BMC domain KH_5 PF13184.6 OAG15798.1 - 8.5 6.6 10.0 8.6 6.5 0.1 5.0 6 0 0 6 6 6 0 NusA-like KH domain VHS PF00790.19 OAG15799.1 - 3e-35 121.1 0.5 5e-35 120.4 0.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAG15799.1 - 2e-16 59.3 0.0 4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG15799.1 - 1.3e-14 53.7 0.0 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG15799.1 - 2.2e-14 52.8 0.0 4.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAG15799.1 - 1.7e-11 44.2 0.0 4.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 OAG15799.1 - 0.022 14.6 4.3 0.056 13.4 4.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 OAG15800.1 - 3.3e-72 243.0 0.0 4.7e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG15800.1 - 3.6e-45 154.3 0.0 5.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAG15800.1 - 9.8e-22 77.1 0.4 2.2e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 OAG15800.1 - 8.5e-08 31.8 0.1 1.9e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG15800.1 - 2.4e-07 29.9 0.0 4.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG15800.1 - 0.0045 16.4 0.5 0.03 13.7 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG15800.1 - 0.0099 15.8 0.1 0.054 13.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG15800.1 - 0.016 14.2 1.1 0.054 12.4 1.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 OAG15800.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain FTA2 PF13095.6 OAG15800.1 - 0.2 11.2 0.3 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1768 PF08719.11 OAG15801.1 - 5.6e-09 36.4 0.4 5.9e-09 36.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_S17 PF00366.20 OAG15801.1 - 0.034 14.2 0.1 0.12 12.5 0.1 1.9 1 1 0 1 1 1 0 Ribosomal protein S17 PHY PF00360.20 OAG15802.1 - 3.5e-28 98.2 0.0 7.4e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 OAG15802.1 - 4.9e-19 68.9 0.1 1.1e-18 67.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG15802.1 - 6.4e-17 61.7 0.1 1.9e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 OAG15802.1 - 5.8e-14 52.9 0.0 3.9e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 OAG15802.1 - 2.2e-12 46.8 1.0 7e-12 45.2 1.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 OAG15802.1 - 1.2e-08 35.5 0.0 6.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 OAG15802.1 - 0.023 14.5 0.3 0.071 12.9 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Flavoprotein PF02441.19 OAG15803.1 - 2.7e-15 56.5 0.0 4.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 OAG15803.1 - 0.01 16.4 0.1 2.9 8.6 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Cyt-b5 PF00173.28 OAG15804.1 - 6.3e-22 77.5 0.2 8.2e-22 77.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U62_UL91 PF17442.2 OAG15804.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins NUC153 PF08159.12 OAG15805.1 - 2.4e-13 49.7 2.6 5.4e-13 48.5 2.6 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 OAG15805.1 - 0.004 18.0 0.0 22 6.1 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG15805.1 - 0.067 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 OAG15806.1 - 1.7e-66 224.7 2.1 1.7e-66 224.7 2.1 5.0 4 2 1 5 5 5 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 OAG15806.1 - 4.6e-60 203.6 8.0 4.6e-60 203.6 8.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 OAG15806.1 - 1.6e-34 119.8 3.3 8.7e-33 114.1 0.0 3.8 3 1 0 3 3 3 1 MID domain of medPIWI DHHC PF01529.20 OAG15808.1 - 1e-34 119.5 1.4 1e-34 119.5 1.4 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 OAG15808.1 - 1.2 9.9 5.2 1.9 9.2 5.2 1.2 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Myb_DNA-bind_2 PF08914.11 OAG15809.1 - 7.8e-23 80.4 1.1 1.9e-22 79.2 1.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 OAG15809.1 - 1.6e-16 60.1 0.1 8e-15 54.7 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 OAG15809.1 - 1.6e-09 38.0 0.0 8.8e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 OAG15809.1 - 0.00012 22.7 0.4 0.00012 22.7 0.4 2.9 2 1 1 3 3 3 1 Rap1, DNA-binding HTH_Tnp_Tc5 PF03221.16 OAG15809.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF3176 PF11374.8 OAG15810.1 - 5.6e-29 100.5 1.1 1.3e-28 99.3 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) LUC7 PF03194.15 OAG15811.1 - 2.2e-73 247.0 4.6 2.6e-73 246.8 4.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus GCOM2 PF15328.6 OAG15811.1 - 0.021 15.2 0.3 0.031 14.7 0.3 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 MCPsignal PF00015.21 OAG15811.1 - 0.031 14.1 0.2 0.049 13.4 0.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TelA PF05816.11 OAG15811.1 - 0.046 12.8 3.4 0.073 12.1 3.4 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF4919 PF16266.5 OAG15811.1 - 0.16 11.9 0.9 0.4 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) GRP PF07172.11 OAG15811.1 - 3.3 8.5 26.3 2.5 8.8 23.7 2.0 2 0 0 2 2 2 0 Glycine rich protein family Gpi16 PF04113.14 OAG15812.1 - 1.5e-238 792.8 0.0 1.8e-238 792.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component ketoacyl-synt PF00109.26 OAG15814.1 - 5.2e-56 190.0 0.0 1.4e-55 188.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG15814.1 - 7.1e-55 185.7 0.0 5.6e-54 182.8 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 OAG15814.1 - 8.2e-52 176.3 0.0 1.6e-51 175.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG15814.1 - 1.3e-48 166.2 0.3 2.2e-48 165.4 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG15814.1 - 5.2e-37 126.5 0.1 1.2e-36 125.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain DUF1769 PF08588.10 OAG15814.1 - 5e-21 74.7 0.5 1.4e-20 73.2 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Methyltransf_12 PF08242.12 OAG15814.1 - 7.1e-21 74.8 0.0 2.3e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG15814.1 - 1.1e-16 62.1 0.0 2.1e-15 58.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 OAG15814.1 - 5.2e-15 55.9 0.1 5.6e-13 49.3 0.1 2.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 OAG15814.1 - 6.1e-14 52.1 0.6 5.1e-13 49.1 0.1 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG15814.1 - 7.6e-14 52.2 0.0 4.7e-13 49.7 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG15814.1 - 1.9e-13 50.6 0.0 4.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15814.1 - 2e-12 47.2 0.0 5.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15814.1 - 1.4e-11 44.9 0.0 5.5e-11 43.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG15814.1 - 4.7e-08 32.7 0.1 6.8e-07 28.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 OAG15814.1 - 2.1e-07 31.2 0.0 6.7e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 OAG15814.1 - 5.7e-07 29.2 1.5 1.9e-06 27.5 0.0 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain ADH_N PF08240.12 OAG15814.1 - 1.5e-05 24.8 0.1 4.1e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 OAG15814.1 - 0.0003 20.2 0.0 0.00082 18.8 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 OAG15814.1 - 0.00071 19.3 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 OAG15814.1 - 0.0018 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_33 PF10017.9 OAG15814.1 - 0.0045 16.2 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent ACP_syn_III PF08545.10 OAG15814.1 - 0.034 14.0 0.1 1 9.3 0.2 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.12 OAG15814.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 OAG15814.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAD_binding_4 PF01565.23 OAG15815.1 - 2.1e-17 63.2 0.2 1.9e-15 56.8 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG15815.1 - 2e-05 24.6 0.1 5.3e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 OAG15816.1 - 5.8e-68 229.7 0.0 6.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pox_P35 PF03213.14 OAG15816.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein p450 PF00067.22 OAG15817.1 - 8.2e-55 186.4 0.0 1.1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLAC9 PF15205.6 OAG15817.1 - 0.12 12.8 0.2 0.33 11.4 0.2 1.7 1 0 0 1 1 1 0 Placenta-specific protein 9 2TM PF13239.6 OAG15817.1 - 0.63 10.4 0.1 0.63 10.4 0.1 1.9 2 0 0 2 2 2 0 2TM domain p450 PF00067.22 OAG15818.1 - 6e-63 213.2 0.0 7.5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_4 PF17784.1 OAG15819.1 - 1.9e-61 207.7 0.0 2.3e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG15819.1 - 0.007 16.8 0.2 0.14 12.6 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family HSP70 PF00012.20 OAG15820.1 - 1.6e-262 872.0 17.6 1.9e-262 871.9 17.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG15820.1 - 3.2e-21 75.5 0.7 3.3e-20 72.1 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 OAG15820.1 - 0.011 15.3 0.3 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF5053 PF16476.5 OAG15820.1 - 0.084 12.6 1.9 0.36 10.5 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5053) FGGY_C PF02782.16 OAG15820.1 - 0.094 12.4 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAG15820.1 - 0.55 10.7 12.4 4 7.9 0.6 3.7 3 2 0 3 3 3 0 Cell division protein FtsA PRANC PF09372.10 OAG15824.1 - 0.059 13.7 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 PRANC domain Oxidored_FMN PF00724.20 OAG15825.1 - 2.6e-67 227.5 0.0 3e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2235 PF09994.9 OAG15826.1 - 3.8e-58 197.1 0.0 5e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Med7 PF05983.11 OAG15827.1 - 1.9e-56 191.2 3.9 2.5e-56 190.8 3.9 1.2 1 0 0 1 1 1 1 MED7 protein ADH_zinc_N PF00107.26 OAG15828.1 - 4.9e-17 62.1 0.1 1e-16 61.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG15828.1 - 2.4e-07 31.8 0.0 3.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG15828.1 - 5.7e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PhoD PF09423.10 OAG15829.1 - 1.6e-113 379.3 7.6 2.1e-113 378.9 7.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAG15829.1 - 7e-34 116.2 0.0 1.6e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain ADH_zinc_N_2 PF13602.6 OAG15829.1 - 2.2e-28 99.9 0.0 1.1e-27 97.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG15829.1 - 2.9e-15 56.4 0.0 8.5e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG15829.1 - 7.6e-05 22.6 3.0 0.00017 21.5 0.1 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Pur_ac_phosph_N PF16656.5 OAG15829.1 - 0.00075 20.0 0.6 0.0023 18.5 0.6 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 OAG15829.1 - 0.14 12.6 0.9 0.37 11.3 0.9 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase HTH_Tnp_Tc5 PF03221.16 OAG15832.1 - 0.13 12.3 0.1 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF1445 PF07286.12 OAG15833.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) FAD_binding_4 PF01565.23 OAG15834.1 - 1.4e-22 79.9 0.1 3.2e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain HET PF06985.11 OAG15835.1 - 1.2e-27 97.1 0.1 2.5e-27 96.0 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.18 OAG15836.1 - 2.1e-11 43.7 17.0 3.1e-11 43.2 17.0 1.2 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 OAG15836.1 - 0.0096 13.9 1.1 0.01 13.8 1.1 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 OAG15836.1 - 0.012 15.9 9.5 0.02 15.2 9.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 OAG15836.1 - 0.051 13.7 3.9 0.074 13.2 3.9 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box PF00646.33 OAG15839.1 - 7.3e-05 22.5 0.7 0.0002 21.2 0.4 1.9 2 0 0 2 2 2 1 F-box domain GFA PF04828.14 OAG15841.1 - 6.1e-09 36.1 0.1 6.1e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme peroxidase PF00141.23 OAG15842.1 - 1.7e-21 77.0 0.4 2.8e-21 76.3 0.4 1.2 1 0 0 1 1 1 1 Peroxidase Phage_term_sma PF07141.11 OAG15842.1 - 0.012 15.4 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit Abhydrolase_3 PF07859.13 OAG15844.1 - 2.4e-27 96.2 0.0 3.1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG15844.1 - 2.3e-13 49.8 0.0 3.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 OAG15844.1 - 0.017 14.0 0.0 0.052 12.4 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family DUF2974 PF11187.8 OAG15844.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) NmrA PF05368.13 OAG15845.1 - 1.2e-30 106.8 0.0 1.5e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG15845.1 - 1.1e-21 77.5 0.1 1.8e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG15845.1 - 8.3e-06 25.4 0.4 8.8e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG15845.1 - 3e-05 24.5 0.1 7.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG15845.1 - 0.00014 22.1 0.1 0.00028 21.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG15845.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 OAG15845.1 - 0.0075 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAG15845.1 - 0.036 13.1 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 OAG15845.1 - 0.085 13.6 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase AvrRpt-cleavage PF05627.11 OAG15845.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr TrkA_N PF02254.18 OAG15845.1 - 0.13 12.5 0.1 0.63 10.3 0.0 2.0 1 1 1 2 2 2 0 TrkA-N domain DUF846 PF05832.12 OAG15846.1 - 0.0025 17.9 1.0 0.0038 17.3 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2070 PF09843.9 OAG15846.1 - 0.73 8.0 4.7 0.79 7.9 4.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HET PF06985.11 OAG15847.1 - 2.9e-30 105.5 0.3 1.5e-21 77.2 0.1 2.5 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 OAG15848.1 - 1.5e-25 89.6 0.7 2.5e-25 88.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain SBP PF03110.14 OAG15850.1 - 0.012 15.9 2.1 0.09 13.1 1.2 2.2 2 0 0 2 2 2 0 SBP domain Rubredoxin_2 PF18073.1 OAG15850.1 - 0.04 13.7 0.4 0.1 12.4 0.4 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain PGG PF13962.6 OAG15850.1 - 0.25 11.2 2.8 1 9.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function XPG_N PF00752.17 OAG15851.1 - 0.0078 16.7 0.1 0.061 13.8 0.1 1.9 1 1 1 2 2 2 1 XPG N-terminal domain DUF5045 PF16464.5 OAG15851.1 - 0.064 13.6 0.3 0.093 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) DUF4303 PF14136.6 OAG15851.1 - 0.082 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Goodbye PF17109.5 OAG15852.1 - 7.3e-15 55.5 0.1 2.7e-14 53.7 0.1 2.0 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 OAG15852.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG15852.1 - 2e-05 25.1 1.0 0.00038 20.9 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 OAG15852.1 - 0.0082 16.2 0.5 2.9 8.2 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2075 PF09848.9 OAG15852.1 - 0.029 13.6 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_12 PF13424.6 OAG15852.1 - 0.036 14.4 1.1 2.5 8.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.17 OAG15852.1 - 0.068 13.0 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type AAA_22 PF13401.6 OAG15852.1 - 0.076 13.3 1.7 0.82 9.9 0.0 3.3 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAG15852.1 - 0.097 13.1 0.0 0.37 11.2 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Cutinase PF01083.22 OAG15853.1 - 2.7e-23 82.8 0.0 2.7e-23 82.8 0.0 2.0 2 1 0 2 2 2 1 Cutinase PPR_long PF17177.4 OAG15853.1 - 0.22 10.8 2.7 8.8 5.6 0.8 2.2 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP Sporozoite_P67 PF05642.11 OAG15853.1 - 0.68 8.0 13.6 0.86 7.6 13.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_1 PF00561.20 OAG15854.1 - 4.5e-16 59.3 0.1 7.9e-16 58.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG15854.1 - 4.8e-10 40.4 0.0 6.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG15854.1 - 1.1e-07 31.4 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 OAG15854.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus TFIIA PF03153.13 OAG15856.1 - 0.48 10.4 16.3 0.4 10.6 14.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.11 OAG15856.1 - 3.8 5.9 11.4 5.7 5.3 11.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2433 PF10360.9 OAG15858.1 - 1.2e-48 164.3 0.0 1.9e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 OAG15858.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG15858.1 - 0.014 15.6 0.0 0.045 13.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 OAG15858.1 - 0.28 11.1 2.8 0.41 10.6 2.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Keratin_2_tail PF16210.5 OAG15858.1 - 1.8 8.8 44.2 4.3 7.6 44.2 1.6 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail HEAT PF02985.22 OAG15859.1 - 5.2e-20 69.8 3.1 0.00047 20.2 0.1 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 OAG15859.1 - 5.2e-17 62.0 11.7 1.1e-06 29.0 0.5 9.2 9 2 1 10 10 8 4 HEAT-like repeat HEAT_2 PF13646.6 OAG15859.1 - 2.5e-16 59.8 2.9 0.00019 21.8 0.1 7.6 6 2 1 7 7 7 4 HEAT repeats IBN_N PF03810.19 OAG15859.1 - 6.5e-11 42.0 1.0 3.6e-10 39.6 0.5 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 OAG15859.1 - 9.1e-09 35.1 2.4 0.98 9.6 0.0 6.9 7 0 0 7 7 6 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OAG15859.1 - 4.7e-08 32.0 0.0 0.019 13.5 0.0 3.8 4 1 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OAG15859.1 - 1.3e-07 32.1 0.0 0.8 10.3 0.0 5.5 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAG15859.1 - 6.9e-07 29.5 0.0 0.2 11.7 0.0 4.9 5 1 0 5 5 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAG15859.1 - 3.9e-05 23.0 0.0 0.0022 17.2 0.0 2.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 OAG15859.1 - 5.4e-05 22.4 0.5 0.31 10.1 0.0 4.8 2 2 0 3 3 3 1 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 OAG15859.1 - 8.6e-05 22.4 0.0 0.61 9.8 0.0 4.1 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OAG15859.1 - 0.00025 21.2 0.0 1.9 8.7 0.0 4.3 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAG15859.1 - 0.00029 20.5 0.0 1.4 8.4 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal DUF4042 PF13251.6 OAG15859.1 - 0.0047 16.7 0.2 6.6 6.4 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) Xpo1 PF08389.12 OAG15859.1 - 0.0055 16.8 0.0 1.1 9.4 0.0 3.3 2 2 0 2 2 2 1 Exportin 1-like protein Tti2 PF10521.9 OAG15859.1 - 0.051 13.1 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Tti2 family NPC1_N PF16414.5 OAG15860.1 - 8.9e-84 280.9 11.8 1.8e-83 279.8 11.8 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAG15860.1 - 4.5e-74 250.0 2.4 1.1e-72 245.3 3.5 2.5 3 1 0 3 3 3 1 Patched family Sterol-sensing PF12349.8 OAG15860.1 - 2.9e-52 176.6 5.4 2.9e-52 176.6 5.4 3.3 2 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OAG15860.1 - 0.00016 20.7 10.0 0.00016 20.7 10.0 2.6 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.19 OAG15860.1 - 0.068 10.8 12.1 0.13 9.9 12.1 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Aldo_ket_red PF00248.21 OAG15861.1 - 4.6e-39 134.4 0.0 8.2e-38 130.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 OAG15862.1 - 6.1e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.14 OAG15864.1 - 0.0036 17.2 3.9 0.0088 15.9 3.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Allexi_40kDa PF05549.11 OAG15864.1 - 0.04 13.4 0.8 0.07 12.6 0.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DHR10 PF18595.1 OAG15864.1 - 1.1 9.3 8.4 2.6 8.2 7.5 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain H_lectin PF09458.10 OAG15865.1 - 3.1e-30 104.2 0.6 7.1e-12 45.3 0.3 3.8 3 0 0 3 3 3 3 H-type lectin domain AA_permease_2 PF13520.6 OAG15866.1 - 3e-54 184.5 43.3 3.7e-54 184.2 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG15866.1 - 1.2e-21 76.9 36.8 1.6e-21 76.5 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease OGG_N PF07934.12 OAG15867.1 - 6.5e-36 123.1 0.1 7e-35 119.7 0.0 2.1 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OAG15867.1 - 9.3e-15 55.0 0.0 1.9e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG15867.1 - 4.2e-05 23.2 0.0 9.8e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 OAG15868.1 - 5.8e-28 96.5 0.0 7.1e-10 38.6 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG15868.1 - 0.00019 21.2 0.1 0.17 11.8 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM PF05172.13 OAG15868.1 - 0.18 11.8 0.0 7.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif adh_short PF00106.25 OAG15869.1 - 2.6e-21 76.0 0.2 4.4e-18 65.5 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15869.1 - 3e-11 43.4 0.0 2.6e-09 37.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15869.1 - 5.9e-07 29.6 0.2 9e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG15869.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2016 PF09436.10 OAG15870.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) ADH_N PF08240.12 OAG15871.1 - 2.3e-24 85.4 1.6 3.6e-24 84.7 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15871.1 - 2.3e-22 79.3 0.0 3.4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG15871.1 - 0.00022 22.3 0.0 0.00037 21.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG15871.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG15871.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 OAG15873.1 - 8.5e-132 440.2 23.1 9.7e-132 440.0 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG15873.1 - 8.4e-24 84.1 51.2 7.2e-23 81.1 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily dUTPase PF00692.19 OAG15874.1 - 7.4e-40 135.6 0.0 9.7e-40 135.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase LCE6A PF15858.5 OAG15874.1 - 0.12 13.2 0.5 0.12 13.2 0.5 2.0 1 1 1 2 2 2 0 Late cornified envelope protein 6A family Phos_pyr_kin PF08543.12 OAG15875.1 - 1.1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAG15875.1 - 2.4e-05 23.8 0.0 8.1e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 OAG15876.1 - 4.1e-53 178.4 2.7 4.1e-53 178.4 2.7 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAG15876.1 - 9e-53 177.8 0.1 8.3e-52 174.7 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rab5ip PF07019.12 OAG15876.1 - 6.3e-17 61.9 0.5 1.1e-16 61.2 0.5 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Rad9 PF04139.13 OAG15876.1 - 1.4e-06 28.0 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 OAG15876.1 - 0.0012 18.1 0.1 0.0044 16.2 0.0 1.9 2 1 0 2 2 2 1 Hus1-like protein Vezatin PF12632.7 OAG15878.1 - 6.5e-66 222.6 0.2 1.1e-65 221.8 0.0 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes DUF2628 PF10947.8 OAG15878.1 - 0.055 13.8 0.6 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) zf-C2H2_4 PF13894.6 OAG15879.1 - 4.5e-06 27.0 0.4 0.0051 17.5 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG15879.1 - 0.00012 22.4 4.8 0.00031 21.0 0.1 3.0 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-BED PF02892.15 OAG15879.1 - 0.036 14.1 0.8 7 6.8 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_aberr PF17017.5 OAG15879.1 - 0.037 14.2 0.0 9.4 6.3 0.0 2.4 1 1 0 2 2 2 0 Aberrant zinc-finger DUF2961 PF11175.8 OAG15879.1 - 0.1 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) DUF4729 PF15866.5 OAG15879.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-RRN7 PF11781.8 OAG15879.1 - 0.25 11.1 2.3 0.4 10.4 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_4 PF13894.6 OAG15880.1 - 7.9e-05 23.2 1.1 0.72 10.8 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG15880.1 - 0.06 13.8 9.9 0.14 12.7 0.1 3.2 2 1 0 2 2 2 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG15880.1 - 0.097 13.3 0.0 0.31 11.7 0.0 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain FAD_binding_3 PF01494.19 OAG15881.1 - 1.1e-17 64.3 0.0 5.9e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG15881.1 - 7.1e-06 25.8 4.7 0.04 13.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG15881.1 - 3.5e-05 23.0 0.7 0.00011 21.4 0.7 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG15881.1 - 3.7e-05 23.0 2.5 3.7e-05 23.0 2.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG15881.1 - 5.7e-05 22.5 3.1 0.015 14.6 1.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG15881.1 - 0.00043 19.7 2.1 0.0007 19.0 2.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG15881.1 - 0.0006 20.0 3.6 0.0074 16.5 2.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG15881.1 - 0.0016 17.2 0.9 0.0069 15.1 0.8 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG15881.1 - 0.0055 15.8 0.7 0.0088 15.2 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG15881.1 - 0.018 13.9 2.3 0.099 11.5 0.4 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 OAG15881.1 - 0.02 14.2 0.2 0.04 13.1 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 OAG15881.1 - 0.043 13.1 0.7 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAG15881.1 - 0.052 12.8 0.1 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG15881.1 - 0.22 12.1 2.6 0.97 10.0 0.4 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG15881.1 - 0.26 11.2 1.2 0.55 10.1 1.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.21 OAG15882.1 - 1.9e-16 60.1 0.0 1.1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG15882.1 - 2.7e-05 23.9 0.6 9.8e-05 22.1 0.1 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 OAG15882.1 - 0.092 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Amidase PF01425.21 OAG15883.1 - 2.9e-88 296.8 0.0 3.9e-88 296.4 0.0 1.2 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 OAG15884.1 - 5.6e-82 275.8 0.0 7.2e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG15884.1 - 3.1e-28 98.9 0.0 6.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAG15884.1 - 1.9e-05 24.1 0.0 7.6e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG15884.1 - 0.00063 18.9 0.1 0.00097 18.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG15884.1 - 0.00088 18.1 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 OAG15884.1 - 0.00092 18.9 0.1 0.14 11.7 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG15884.1 - 0.0037 16.5 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAG15884.1 - 0.0047 17.1 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG15884.1 - 0.01 16.3 0.0 0.077 13.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG15884.1 - 0.021 15.1 0.0 0.075 13.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAG15884.1 - 0.041 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG15884.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Inj_translocase PF16928.5 OAG15884.1 - 0.61 9.5 2.2 0.34 10.3 0.1 1.6 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome MFS_1 PF07690.16 OAG15885.1 - 1.4e-31 109.7 24.3 2e-31 109.2 24.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.9 OAG15885.1 - 0.06 13.6 0.8 0.36 11.1 0.1 2.4 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fungal_trans PF04082.18 OAG15886.1 - 1.4e-43 148.9 3.0 2.4e-43 148.1 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ald_Xan_dh_C2 PF02738.18 OAG15887.1 - 3.5e-198 659.5 0.0 4.8e-198 659.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAG15887.1 - 2.4e-39 134.8 0.0 4.8e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OAG15887.1 - 4.4e-32 110.3 0.0 1.5e-31 108.6 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 OAG15887.1 - 4e-31 107.6 0.0 9e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OAG15887.1 - 1.5e-25 89.0 0.1 4.2e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OAG15887.1 - 8.8e-08 32.0 1.4 3.4e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Oxidored_FMN PF00724.20 OAG15888.1 - 2.8e-91 306.3 0.0 3.8e-89 299.3 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.23 OAG15889.1 - 2.3e-14 53.9 0.0 4.4e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 OAG15890.1 - 2.8e-08 33.6 0.1 5.8e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAG15890.1 - 0.0015 18.2 2.0 0.04 13.5 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.12 OAG15890.1 - 0.0069 16.6 1.5 0.15 12.3 0.3 2.3 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region adh_short_C2 PF13561.6 OAG15891.1 - 1.4e-28 100.0 0.0 5.5e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG15891.1 - 6.5e-21 74.7 0.0 1.2e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG15891.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 2 0 0 2 2 2 0 KR domain HSCB_C PF07743.13 OAG15892.1 - 5e-21 75.0 14.2 6.8e-21 74.5 10.5 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAG15892.1 - 1.4e-06 28.3 0.5 3.8e-06 26.9 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DMP1 PF07263.11 OAG15892.1 - 0.0056 15.6 0.7 0.0056 15.6 0.7 1.6 2 0 0 2 2 2 1 Dentin matrix protein 1 (DMP1) Malate_DH PF12434.8 OAG15893.1 - 0.11 12.5 1.1 0.44 10.6 1.1 2.0 1 0 0 1 1 1 0 Malate dehydrogenase enzyme T2SSF PF00482.23 OAG15893.1 - 0.2 11.6 1.7 1.2 9.1 0.1 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Ribosomal_L17 PF01196.19 OAG15893.1 - 0.72 10.8 2.8 1.1 10.1 0.1 2.6 3 1 0 3 3 3 0 Ribosomal protein L17 DUF924 PF06041.11 OAG15894.1 - 6.9e-45 153.4 0.1 8.3e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) p450 PF00067.22 OAG15895.1 - 4.2e-69 233.5 0.0 5.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMD PF08397.11 OAG15896.1 - 0.12 11.7 0.6 0.21 10.9 0.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Fungal_trans PF04082.18 OAG15897.1 - 4.1e-11 42.4 0.0 8.7e-11 41.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 OAG15898.1 - 2.5e-65 216.5 1.3 1.4e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_transf_3 PF02515.17 OAG15899.1 - 1.6e-126 422.4 0.0 1.8e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III HgmA PF04209.13 OAG15900.1 - 8.1e-142 472.9 0.0 9.6e-142 472.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Lyase_1 PF00206.20 OAG15901.1 - 3.1e-46 158.2 0.0 6.9e-46 157.1 0.0 1.5 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG15901.1 - 1.7e-20 73.3 0.1 3.6e-19 69.1 0.0 2.6 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Thiolase_N PF00108.23 OAG15902.1 - 1.9e-71 240.5 0.2 8.6e-71 238.3 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG15902.1 - 3.5e-44 149.4 0.1 4.3e-43 145.9 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG15902.1 - 2.3e-05 24.1 0.1 5.8e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain CoA_trans PF01144.23 OAG15903.1 - 2.8e-95 317.8 5.3 2.2e-56 190.7 0.9 2.3 2 0 0 2 2 2 2 Coenzyme A transferase Fe-ADH PF00465.19 OAG15903.1 - 4.4e-71 239.6 0.5 7.6e-71 238.8 0.5 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG15903.1 - 1.1e-15 58.1 0.1 2.2e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PFK PF00365.20 OAG15903.1 - 0.083 12.2 0.4 0.24 10.7 0.2 1.8 2 0 0 2 2 2 0 Phosphofructokinase NAD_binding_10 PF13460.6 OAG15904.1 - 2.3e-11 43.9 0.0 1.3e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 OAG15904.1 - 0.00016 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG15904.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 OAG15905.1 - 1.2e-28 100.3 0.1 1.8e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG15905.1 - 5.1e-26 91.3 0.0 9.4e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG15905.1 - 0.00062 20.3 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent COesterase PF00135.28 OAG15906.1 - 2.4e-53 181.8 0.0 3.2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG15906.1 - 7e-06 26.0 0.1 6.8e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG15906.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 OAG15906.1 - 0.27 9.7 0.0 0.45 9.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lactamase_B PF00753.27 OAG15907.1 - 2.8e-07 30.8 2.3 7e-07 29.5 2.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG15907.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG15907.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RecX PF02631.16 OAG15907.1 - 0.18 12.3 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 RecX family p450 PF00067.22 OAG15908.1 - 3.6e-56 190.8 0.1 4.4e-56 190.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3_C PF01915.22 OAG15909.1 - 5e-41 140.9 0.0 8.3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG15909.1 - 6.3e-36 124.4 0.0 1e-35 123.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG15909.1 - 3e-07 30.5 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-MYND PF01753.18 OAG15910.1 - 8.3e-05 22.6 17.1 8.3e-05 22.6 17.1 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 OAG15910.1 - 1.2 9.5 14.4 3.4 8.1 14.4 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ABM PF03992.16 OAG15911.1 - 3.5e-16 59.1 0.0 4.6e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Peptidase_S51 PF03575.17 OAG15912.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 RNA_pol_Rbc25 PF08292.12 OAG15913.1 - 2.2e-34 118.4 1.1 4.2e-34 117.6 1.1 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAG15913.1 - 3.1e-14 53.1 0.0 6.9e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAG15913.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 S1 RNA binding domain NUFIP1 PF10453.9 OAG15914.1 - 4.4e-10 39.2 0.9 1.2e-09 37.8 0.9 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 OAG15914.1 - 3.8e-05 23.5 0.7 6.4e-05 22.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG15914.1 - 0.014 15.2 2.0 0.022 14.5 2.0 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG15914.1 - 0.049 13.7 5.0 0.085 12.9 5.0 1.4 1 0 0 1 1 1 0 Zinc finger domain HCV_NS4a PF01006.20 OAG15914.1 - 0.16 11.8 0.2 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Cupin_7 PF12973.7 OAG15915.1 - 0.024 14.6 0.1 0.046 13.6 0.1 1.7 1 1 0 1 1 1 0 ChrR Cupin-like domain PI-PLC-X PF00388.19 OAG15916.1 - 5.2e-63 211.0 0.0 7.7e-63 210.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG15916.1 - 2.9e-38 130.8 0.0 5.1e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAG15916.1 - 7.9e-06 26.1 0.0 4.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 C2 domain D-ser_dehydrat PF14031.6 OAG15917.1 - 0.042 14.5 0.1 0.043 14.5 0.1 1.1 1 0 0 1 1 1 0 Putative serine dehydratase domain zf-NADH-PPase PF09297.11 OAG15917.1 - 0.13 12.0 4.6 4.4 7.0 0.5 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ADH_N_2 PF16884.5 OAG15919.1 - 2.2e-31 108.0 0.0 4.7e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG15919.1 - 2.6e-19 69.5 0.0 4.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG15919.1 - 2e-10 41.9 0.1 3.7e-10 41.0 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HET PF06985.11 OAG15920.1 - 1.6e-28 99.9 0.7 3.5e-28 98.8 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PDZ_6 PF17820.1 OAG15920.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Dus PF01207.17 OAG15921.1 - 1e-45 156.2 0.0 3.7e-45 154.3 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ku_C PF03730.14 OAG15921.1 - 0.65 10.7 5.2 0.83 10.4 3.5 2.0 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm CorA PF01544.18 OAG15922.1 - 4.6e-07 29.5 0.0 7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BLM_N PF16202.5 OAG15922.1 - 0.039 13.1 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein SecE PF00584.20 OAG15922.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex GH131_N PF18271.1 OAG15923.1 - 1.4e-76 257.6 0.1 1.6e-76 257.4 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 OAG15923.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Pirin PF02678.16 OAG15924.1 - 9.8e-30 102.7 0.0 1.9e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OAG15924.1 - 1.2e-26 93.0 0.0 7e-25 87.4 0.0 2.4 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAG15924.1 - 1.9e-08 33.9 0.3 4.1e-06 26.4 0.5 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG15924.1 - 0.067 12.9 0.1 0.86 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DIOX_N PF14226.6 OAG15925.1 - 2.5e-29 102.4 0.1 4.3e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG15925.1 - 6.2e-23 81.2 0.1 1.7e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 OAG15926.1 - 1.4e-25 89.9 0.0 1.8e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG15926.1 - 8.2e-19 68.1 0.0 1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG15926.1 - 2.3e-09 37.4 0.0 3.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG15926.1 - 0.062 12.6 0.0 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F-box-like PF12937.7 OAG15927.1 - 0.011 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 OAG15927.1 - 0.02 14.6 0.0 10 6.0 0.0 2.8 1 1 0 2 2 2 0 Leucine rich repeat p450 PF00067.22 OAG15928.1 - 1.4e-70 238.3 0.0 1.7e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 OAG15929.1 - 1.2e-12 48.3 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG15929.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 OAG15929.1 - 0.11 12.0 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family 2OG-FeII_Oxy_2 PF13532.6 OAG15931.1 - 7.7e-29 101.3 0.0 1e-28 100.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPATA6 PF14909.6 OAG15931.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Fungal_trans PF04082.18 OAG15932.1 - 1.8e-14 53.5 0.0 3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG15932.1 - 1.4e-06 28.3 11.1 2.4e-06 27.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 OAG15932.1 - 0.07 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ApoB100_C PF12491.8 OAG15935.1 - 0.15 12.0 1.0 14 5.7 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal ADH_zinc_N PF00107.26 OAG15936.1 - 1.1e-09 38.3 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG15936.1 - 0.00062 19.6 0.0 0.01 15.7 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Mid2 PF04478.12 OAG15937.1 - 0.03 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 OAG15937.1 - 0.043 12.6 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless PAP2 PF01569.21 OAG15937.1 - 0.065 13.0 1.4 0.11 12.3 1.4 1.6 1 1 0 1 1 1 0 PAP2 superfamily DUF2970 PF11174.8 OAG15937.1 - 0.2 11.5 1.6 0.35 10.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) LANC_like PF05147.13 OAG15938.1 - 9.1e-32 110.0 0.0 6.3e-31 107.2 0.0 1.9 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein Tyrosinase PF00264.20 OAG15940.1 - 2.4e-36 126.1 1.4 2.8e-36 125.9 0.2 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG15940.1 - 1.3e-12 48.4 0.0 3.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Tyosinase C-terminal domain Methyltransf_25 PF13649.6 OAG15941.1 - 3.1e-14 53.5 0.0 6.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15941.1 - 7.9e-12 45.2 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15941.1 - 9.9e-12 45.4 0.0 2.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG15941.1 - 4.4e-11 43.4 0.0 8.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG15941.1 - 2.1e-09 37.4 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG15941.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OAG15941.1 - 0.00033 20.3 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OAG15941.1 - 0.0019 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 OAG15941.1 - 0.0035 17.5 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 OAG15941.1 - 0.0041 16.6 0.0 0.67 9.4 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 OAG15941.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 OAG15941.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_33 PF10017.9 OAG15941.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_5 PF01795.19 OAG15941.1 - 0.025 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_4 PF02390.17 OAG15941.1 - 0.026 14.0 0.0 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase IBR PF01485.21 OAG15942.1 - 1.7e-07 31.4 6.0 1.7e-07 31.4 6.0 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Rac1 PF09632.10 OAG15942.1 - 0.2 10.8 0.8 0.34 10.0 0.1 1.7 2 0 0 2 2 2 0 Rac1-binding domain RhoGAP PF00620.27 OAG15943.1 - 1.2e-36 125.8 0.9 2.3e-36 124.9 0.4 1.7 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAG15943.1 - 4.9e-27 93.9 36.6 1.4e-11 44.4 5.2 5.1 5 0 0 5 5 5 4 LIM domain CLZ PF16526.5 OAG15943.1 - 0.098 13.0 0.1 23 5.5 0.0 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RNA_pol_Rpb4 PF03874.16 OAG15944.1 - 2.6e-15 56.8 0.6 3.4e-15 56.5 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1878 PF08963.10 OAG15946.1 - 0.024 15.1 0.1 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) DUF3645 PF12359.8 OAG15946.1 - 0.12 11.8 0.4 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) ADH_N PF08240.12 OAG15947.1 - 5.9e-25 87.3 4.0 9.7e-25 86.6 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG15947.1 - 2.4e-18 66.3 0.0 4.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG15947.1 - 0.00034 20.0 0.1 0.00064 19.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG15947.1 - 0.0007 20.6 0.0 0.0011 20.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG15947.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAG15948.1 - 2.7e-17 63.0 0.1 1e-16 61.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAG15948.1 - 8.4e-05 21.8 0.1 0.00018 20.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG15948.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG15948.1 - 0.0016 17.8 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG15948.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG15948.1 - 0.068 12.4 0.0 0.73 9.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG15948.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 OAG15948.1 - 0.22 10.5 0.9 2.4 7.1 0.5 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein Methyltransf_23 PF13489.6 OAG15949.1 - 2.6e-19 69.7 0.0 3.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG15949.1 - 1.2e-12 48.4 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG15949.1 - 6e-11 42.8 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG15949.1 - 8e-08 32.9 0.0 4.9e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG15949.1 - 9.1e-07 28.8 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 OAG15949.1 - 0.00046 19.6 0.0 0.0037 16.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG15949.1 - 0.0039 16.5 0.0 0.0099 15.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 OAG15949.1 - 0.0041 16.7 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG15949.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAG15949.1 - 0.054 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 OAG15949.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1211 PF06736.11 OAG15951.1 - 7.7 7.0 10.0 0.14 12.6 0.7 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1211) AA_permease_2 PF13520.6 OAG15952.1 - 1e-44 153.1 35.3 1.4e-44 152.6 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG15952.1 - 1.5e-16 60.1 35.1 2.6e-16 59.3 35.1 1.4 1 1 0 1 1 1 1 Amino acid permease CENP-F_leu_zip PF10473.9 OAG15953.1 - 3.3e-17 62.8 269.1 8.5e-05 22.6 0.9 19.3 3 2 16 20 20 20 14 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OAG15953.1 - 1.1e-10 42.1 303.1 0.077 13.2 16.4 16.8 1 1 16 17 17 17 14 Autophagy protein 16 (ATG16) Filament PF00038.21 OAG15953.1 - 1.8e-08 34.3 228.2 0.00039 20.1 33.4 11.0 3 1 7 10 10 10 6 Intermediate filament protein Fez1 PF06818.15 OAG15953.1 - 0.00013 22.5 20.3 0.00013 22.5 20.3 14.0 4 2 10 14 14 14 5 Fez1 TolA_bind_tri PF16331.5 OAG15953.1 - 0.02 15.0 0.4 0.02 15.0 0.4 19.4 5 3 17 23 23 23 0 TolA binding protein trimerisation DUF1664 PF07889.12 OAG15953.1 - 0.28 11.2 142.0 0.28 11.2 6.1 16.7 7 4 8 16 16 16 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_1 PF00441.24 OAG15954.1 - 3.3e-37 128.0 6.4 5.5e-37 127.3 6.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG15954.1 - 4.5e-30 104.6 0.0 1.2e-29 103.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG15954.1 - 2.6e-23 82.0 0.0 7e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG15954.1 - 9.1e-15 55.1 1.6 1.5e-14 54.4 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAG15954.1 - 0.00016 21.5 0.0 0.00047 19.9 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 OAG15954.1 - 0.082 13.0 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Staphylococcal AgrD protein Glyco_hydro_16 PF00722.21 OAG15955.1 - 2.6e-41 141.0 2.2 3.2e-41 140.7 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 PAP_PilO PF06864.12 OAG15955.1 - 0.073 11.9 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) SF3a60_bindingd PF12108.8 OAG15957.1 - 0.07 13.0 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SRA1 PF07304.11 OAG15957.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) SprT-like PF10263.9 OAG15958.1 - 0.00079 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family RRM_1 PF00076.22 OAG15959.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP PF03399.16 OAG15959.1 - 0.1 11.9 0.1 0.29 10.5 0.1 1.7 1 0 0 1 1 1 0 SAC3/GANP family IL4 PF00727.18 OAG15960.1 - 0.13 12.5 0.5 0.21 11.8 0.5 1.3 1 0 0 1 1 1 0 Interleukin 4 SprT-like PF10263.9 OAG15961.1 - 9.1e-06 25.5 0.3 3.1e-05 23.8 0.3 1.9 1 1 0 1 1 1 1 SprT-like family zf-MIZ PF02891.20 OAG15962.1 - 2.9e-11 42.9 1.5 2.9e-11 42.9 1.5 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAG15962.1 - 0.039 13.8 0.6 0.087 12.7 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SH3_9 PF14604.6 OAG15963.1 - 1.9e-13 50.0 0.1 3.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG15963.1 - 1.5e-11 43.7 0.0 3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 OAG15963.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAG15963.1 - 2.4e-09 37.7 0.0 1.4e-08 35.2 0.0 2.4 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 OAG15963.1 - 7.4e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 OAG15963.1 - 0.0019 18.6 0.0 0.0067 16.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 OAG15963.1 - 0.0074 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 OAG15963.1 - 0.067 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Fringe PF02434.16 OAG15964.1 - 1.2e-09 38.0 0.1 1.9e-08 34.1 0.1 2.4 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 OAG15964.1 - 0.00087 19.1 0.8 0.0018 18.1 0.8 1.5 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.12 OAG15964.1 - 0.0022 17.4 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_1 PF00024.26 OAG15964.1 - 0.01 15.8 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 OAG15964.1 - 0.014 15.1 1.3 0.025 14.3 1.3 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Galactosyl_T PF01762.21 OAG15964.1 - 0.029 14.2 0.0 1 9.1 0.0 2.6 1 1 0 1 1 1 0 Galactosyltransferase YppF PF14178.6 OAG15964.1 - 0.083 12.8 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 YppF-like protein Glyco_hydro_45 PF02015.16 OAG15965.1 - 1e-87 293.4 17.2 1.2e-87 293.2 17.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Sulfate_transp PF00916.20 OAG15966.1 - 2.2e-110 369.0 20.8 2.8e-110 368.7 20.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG15966.1 - 3.3e-08 33.2 0.0 6.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAG15966.1 - 0.00024 21.5 5.2 0.00024 21.5 5.2 3.2 2 2 1 3 3 3 2 Molybdate transporter of MFS superfamily YdjM PF04307.14 OAG15966.1 - 0.1 11.9 2.6 0.42 9.9 2.6 2.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Amidohydro_1 PF01979.20 OAG15967.1 - 1.9e-23 83.4 0.0 7.6e-23 81.4 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG15967.1 - 5e-10 39.4 0.0 6.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Maf PF02545.14 OAG15968.1 - 1.7e-51 174.3 0.2 2e-51 174.1 0.2 1.0 1 0 0 1 1 1 1 Maf-like protein ADH_zinc_N PF00107.26 OAG15969.1 - 3.5e-20 72.3 0.0 5.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG15969.1 - 3.1e-18 65.6 0.0 5.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAG15969.1 - 1.5e-07 32.5 0.0 2.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ETRAMP PF09716.10 OAG15970.1 - 0.047 13.7 0.0 0.047 13.7 0.0 2.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) MaAIMP_sms PF16951.5 OAG15970.1 - 0.13 12.0 2.4 0.29 10.9 0.0 2.6 3 0 0 3 3 3 0 Putative methionine and alanine importer, small subunit Sulf_transp PF04143.14 OAG15970.1 - 6.8 6.2 10.3 1.5 8.3 4.2 2.7 2 1 0 2 2 2 0 Sulphur transport DUF5083 PF16890.5 OAG15971.1 - 0.094 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Amidohydro_1 PF01979.20 OAG15973.1 - 2.1e-76 257.5 1.1 3.6e-76 256.7 0.6 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 OAG15973.1 - 4.5e-56 188.4 2.3 9.1e-56 187.4 2.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 OAG15973.1 - 1.4e-40 137.2 0.4 3.5e-40 136.0 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 OAG15973.1 - 1.1e-37 128.3 0.1 2.5e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 OAG15973.1 - 1.8e-06 27.7 0.3 6.2e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family RRM_1 PF00076.22 OAG15975.1 - 9.7e-47 156.7 0.0 6.4e-17 61.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG15975.1 - 1.6e-07 31.2 0.3 0.0013 18.7 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG15975.1 - 1e-05 25.5 0.0 0.001 19.1 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 OAG15975.1 - 0.00022 21.0 0.0 0.048 13.5 0.0 3.1 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG15975.1 - 0.00084 19.4 0.7 0.044 13.9 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 OAG15975.1 - 0.018 14.6 0.0 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Scytalone_dh PF02982.14 OAG15977.1 - 1.2e-87 291.7 0.9 1.4e-87 291.4 0.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 OAG15977.1 - 2.7e-08 34.0 0.2 3.4e-08 33.7 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain HET PF06985.11 OAG15978.1 - 5.8e-26 91.6 0.2 1.1e-25 90.7 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_15 PF17032.5 OAG15979.1 - 3.4e-05 24.5 0.3 4.7e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family Ocnus PF05005.15 OAG15979.1 - 0.064 13.4 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) RIG-I_C-RD PF11648.8 OAG15979.1 - 0.068 13.4 0.4 0.081 13.2 0.4 1.1 1 0 0 1 1 1 0 C-terminal domain of RIG-I Dynein_light PF01221.18 OAG15980.1 - 2e-40 137.0 2.1 2.3e-40 136.8 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M24 PF00557.24 OAG15980.1 - 0.065 12.9 0.1 0.075 12.7 0.1 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 RRM_1 PF00076.22 OAG15981.1 - 2e-72 239.0 3.0 1.7e-16 59.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG15981.1 - 2.7e-15 56.0 0.0 1.1e-05 25.1 0.0 5.3 5 0 0 5 5 5 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAG15981.1 - 3.8e-06 26.9 0.2 0.0031 17.6 0.0 4.1 4 0 0 4 4 4 1 Limkain b1 RRM_7 PF16367.5 OAG15981.1 - 4.7e-06 26.6 0.1 5.1 7.3 0.0 4.6 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 OAG15981.1 - 2e-05 24.6 3.2 6.3 6.9 0.0 5.1 4 1 1 5 5 5 3 RNA binding motif Nup35_RRM_2 PF14605.6 OAG15981.1 - 3.3e-05 23.8 0.1 0.04 13.9 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 OAG15981.1 - 0.015 15.3 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 RL domain TEA PF01285.18 OAG15982.1 - 6.3e-24 83.8 0.1 1.5e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 TEA/ATTS domain dsrm PF00035.26 OAG15983.1 - 4.9e-05 23.9 0.1 0.94 10.2 0.0 4.1 3 1 0 3 3 3 2 Double-stranded RNA binding motif DUF3446 PF11928.8 OAG15983.1 - 2.1 8.7 9.9 8.9 6.7 3.2 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Arm-DNA-bind_4 PF14657.6 OAG15983.1 - 2.3 8.0 8.8 23 4.8 0.4 4.0 3 0 0 3 3 3 0 Arm DNA-binding domain HMG_box PF00505.19 OAG15984.1 - 8.9e-06 26.0 5.4 8.9e-06 26.0 5.4 3.4 3 1 0 3 3 3 1 HMG (high mobility group) box ExsD PF16806.5 OAG15984.1 - 0.042 13.8 0.5 0.078 12.9 0.5 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD CN_hydrolase PF00795.22 OAG15985.1 - 6.2e-58 196.2 0.0 7e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 OAG15986.1 - 4.3e-14 52.2 41.3 4.3e-14 52.2 41.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG15986.1 - 1.8e-06 27.7 7.3 1.8e-06 27.7 7.3 2.8 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Cutinase PF01083.22 OAG15987.1 - 5.1e-43 147.1 1.9 7e-43 146.6 1.9 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG15987.1 - 0.00011 21.9 0.3 0.00018 21.1 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG15987.1 - 0.0006 19.8 0.0 0.00093 19.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 OAG15987.1 - 0.002 18.0 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 OAG15987.1 - 0.016 15.1 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OAG15987.1 - 0.03 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 OAG15987.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_M28 PF04389.17 OAG15988.1 - 3.9e-29 101.8 0.1 9.9e-29 100.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG15988.1 - 1.1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.21 OAG15988.1 - 0.0013 19.0 0.3 0.0035 17.6 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_M42 PF05343.14 OAG15988.1 - 0.0018 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.15 OAG15988.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin DUF3807 PF12720.7 OAG15991.1 - 6.6e-48 163.4 4.4 7.7e-48 163.2 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Fasciclin PF02469.22 OAG15992.1 - 0.0025 18.1 0.0 0.006 16.8 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Lactamase_B PF00753.27 OAG15993.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RecR PF02132.15 OAG15993.1 - 0.33 10.6 2.4 0.7 9.5 2.4 1.5 1 0 0 1 1 1 0 RecR protein DPPIV_N PF00930.21 OAG15994.1 - 5.3e-111 370.8 0.7 7.2e-111 370.4 0.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAG15994.1 - 2.8e-56 190.3 2.2 5.8e-56 189.3 2.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG15994.1 - 1.2e-08 34.9 1.0 1.8e-07 31.0 0.4 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 OAG15994.1 - 0.0018 18.9 0.3 0.36 11.4 0.1 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG15994.1 - 0.004 16.8 0.1 0.026 14.2 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 OAG15994.1 - 0.1 11.1 0.0 0.75 8.2 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SHS2_Rpb7-N PF03876.17 OAG15995.1 - 4.6e-13 49.3 0.0 7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAG15995.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OAG15995.1 - 0.00061 20.0 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 OAG15996.1 - 2.7e-25 88.3 1.1 4.2e-25 87.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 OAG15997.1 - 2.9e-73 246.0 0.0 4.4e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAG15997.1 - 3.9e-47 159.7 0.4 6.9e-47 158.9 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAG15997.1 - 8.4e-16 58.2 2.6 2e-15 57.0 2.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SNARE_assoc PF09335.11 OAG15998.1 - 2.6e-15 56.9 5.7 2.6e-15 56.9 5.7 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein ATP-synt_E PF05680.12 OAG15998.1 - 0.043 14.2 0.2 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF1771 PF08590.10 OAG15999.1 - 1.6e-14 54.0 9.8 3.3e-14 53.0 9.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 OAG15999.1 - 3.4e-08 33.2 6.2 0.00095 19.0 1.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG15999.1 - 1.2e-07 31.5 10.5 8.8e-06 25.6 1.4 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAG15999.1 - 1.1e-05 25.0 11.2 0.00021 21.0 0.4 2.9 2 1 0 2 2 2 2 CCCH-type zinc finger Smr PF01713.21 OAG15999.1 - 2.5e-05 24.5 0.0 6.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 OAG15999.1 - 4.5e-05 23.8 10.6 0.0035 17.8 0.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OAG15999.1 - 0.0036 17.5 2.5 0.24 11.6 0.1 2.4 1 1 1 2 2 2 2 Zinc-finger containing family UL2 PF08196.11 OAG15999.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 UL2 protein Torus PF16131.5 OAG15999.1 - 0.18 12.5 7.0 0.2 12.3 0.6 2.4 1 1 1 2 2 2 0 Torus domain zf-C3H1 PF10650.9 OAG15999.1 - 8.3 6.2 5.5 31 4.4 0.8 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain Cnn_1N PF07989.11 OAG16000.1 - 3.7 7.8 6.2 21 5.4 0.6 3.7 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 FAA_hydrolase PF01557.18 OAG16001.1 - 4e-53 180.3 0.0 4.8e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MCCD1 PF15707.5 OAG16002.1 - 0.072 13.5 0.1 0.089 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 PWI PF01480.17 OAG16004.1 - 4.2e-30 103.9 0.4 7.5e-30 103.1 0.4 1.4 1 0 0 1 1 1 1 PWI domain AAA_18 PF13238.6 OAG16004.1 - 0.11 13.1 0.2 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Phage_AlpA PF05930.12 OAG16004.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) PP2C PF00481.21 OAG16005.1 - 2.5e-05 24.0 0.1 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 OAG16005.1 - 7.5e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3456 PF11938.8 OAG16005.1 - 0.079 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP CBS PF00571.28 OAG16006.1 - 9.9e-06 25.9 0.0 0.45 11.0 0.0 3.1 2 1 0 2 2 2 2 CBS domain PWWP PF00855.17 OAG16007.1 - 1.1e-14 54.6 0.0 1.1e-14 54.6 0.0 3.4 2 1 1 3 3 3 1 PWWP domain Med26 PF08711.11 OAG16007.1 - 0.069 13.2 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Carb_kinase PF01256.17 OAG16008.1 - 7.1e-59 199.2 0.2 9.2e-59 198.9 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 OAG16008.1 - 6.8e-05 22.4 0.1 0.00011 21.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.24 OAG16008.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG16008.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase zf-BED PF02892.15 OAG16010.1 - 2.1e-06 27.7 2.8 0.028 14.5 0.0 2.7 2 0 0 2 2 2 2 BED zinc finger FdhD-NarQ PF02634.15 OAG16011.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family Bromo_TP PF07524.13 OAG16012.1 - 4.9e-08 32.9 0.2 1.4e-07 31.4 0.0 1.9 3 0 0 3 3 3 1 Bromodomain associated TFIID-31kDa PF02291.15 OAG16012.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Phage_int_SAM_4 PF13495.6 OAG16012.1 - 0.051 14.1 0.2 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain TAFII55_N PF04658.13 OAG16013.1 - 5.8e-45 152.9 0.1 3e-43 147.3 0.0 2.6 2 0 0 2 2 2 1 TAFII55 protein conserved region AAA_13 PF13166.6 OAG16013.1 - 8 5.0 17.8 11 4.5 17.8 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OAG16014.1 - 5.4e-45 153.8 0.0 8.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16014.1 - 1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG16014.1 - 8.7e-05 22.6 0.1 0.25 11.2 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OAG16014.1 - 0.0052 16.4 0.1 0.011 15.4 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAG16014.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.12 OAG16015.1 - 2.6e-07 30.7 0.7 6.5e-07 29.5 0.7 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAG16015.1 - 5.2e-07 29.6 0.0 0.0035 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG16015.1 - 1.8e-05 24.5 2.0 2.4e-05 24.1 0.4 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C WD40 PF00400.32 OAG16016.1 - 3.1e-30 103.7 17.6 4.3e-09 36.8 0.2 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat PRP4 PF08799.11 OAG16016.1 - 1.2e-14 53.6 1.0 2.6e-14 52.4 1.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 OAG16016.1 - 1.2e-13 51.2 0.0 0.083 13.2 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG16016.1 - 0.00021 21.3 0.0 6 6.7 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG16016.1 - 0.00057 19.3 0.0 0.63 9.3 0.0 3.4 3 0 0 3 3 3 1 WD40-like domain Toprim_3 PF13362.6 OAG16016.1 - 0.05 14.0 0.6 0.098 13.0 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Nbas_N PF15492.6 OAG16016.1 - 0.067 12.5 0.0 0.56 9.5 0.0 2.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OAG16016.1 - 0.41 9.2 1.2 5.1 5.6 0.4 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 bZIP_Maf PF03131.17 OAG16017.1 - 1.5e-09 38.3 8.6 3.6e-09 37.0 6.6 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 OAG16017.1 - 1.2e-07 31.7 7.4 1.2e-07 31.7 7.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG16017.1 - 9.2e-07 28.9 9.9 9.2e-07 28.9 9.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper UPF0242 PF06785.11 OAG16017.1 - 0.35 10.9 16.2 0.59 10.2 15.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 OAG16017.1 - 6.5 7.1 10.5 3.1 8.1 8.0 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sel1 PF08238.12 OAG16018.1 - 5.3e-17 61.9 6.6 7.5e-07 29.6 0.5 4.3 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 OAG16018.1 - 0.038 14.6 3.0 0.23 12.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 OAG16019.1 - 1.9e-07 31.3 3.9 1.9e-07 31.3 3.9 3.1 1 1 2 3 3 3 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAG16019.1 - 0.00024 20.8 1.6 0.00024 20.8 1.6 4.5 4 0 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG16019.1 - 0.0042 17.1 30.2 0.46 10.6 0.9 5.5 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH PF00642.24 OAG16019.1 - 0.0069 16.3 1.0 0.0069 16.3 1.0 5.4 6 0 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 OAG16019.1 - 0.015 15.0 2.7 0.1 12.3 0.2 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain DnaB_bind PF10410.9 OAG16019.1 - 0.22 11.7 0.1 0.37 11.0 0.1 1.3 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MSA-2c PF12238.8 OAG16019.1 - 0.31 11.0 2.3 0.67 9.9 2.3 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Torus PF16131.5 OAG16019.1 - 2.4 8.9 23.9 2 9.1 1.0 4.8 1 1 4 5 5 5 0 Torus domain TspO_MBR PF03073.15 OAG16022.1 - 8e-43 145.7 9.8 1.2e-42 145.2 9.8 1.2 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 OAG16023.1 - 1.1e-29 102.8 10.6 1.1e-29 102.8 10.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OAG16023.1 - 8.5e-14 52.4 1.0 8.5e-14 52.4 1.0 2.3 1 1 1 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 OAG16023.1 - 8.6e-12 44.7 0.5 2.6e-11 43.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) DUF3818 PF12825.7 OAG16024.1 - 1.4e-133 445.2 0.7 2.3e-133 444.4 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG16024.1 - 2.1e-40 137.7 0.7 4.9e-40 136.5 0.7 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAG16024.1 - 5.2e-11 42.5 0.0 2.1e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 PX domain GFD1 PF17331.2 OAG16024.1 - 0.59 10.4 8.6 0.026 14.7 2.4 2.0 2 0 0 2 2 2 0 GFD1 mRNA transport factor COPIIcoated_ERV PF07970.12 OAG16025.1 - 2.1e-85 286.1 0.2 9.6e-85 283.9 0.3 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG16025.1 - 1.2e-30 105.7 0.0 4.7e-29 100.6 0.0 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 OAG16026.1 - 1.6e-12 46.9 0.8 4.8e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 TAP C-terminal domain UBA_4 PF14555.6 OAG16026.1 - 0.0051 16.6 0.5 0.013 15.3 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain LRR_4 PF12799.7 OAG16026.1 - 0.36 11.3 2.1 1.9 9.0 0.1 2.7 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Sulfate_transp PF00916.20 OAG16027.1 - 1.1e-105 353.5 22.1 1.4e-105 353.2 22.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG16027.1 - 5.4e-09 35.7 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAG16027.1 - 0.0068 16.8 20.3 0.012 16.0 3.6 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 OAG16027.1 - 0.018 15.0 0.5 0.018 15.0 0.5 3.3 4 0 0 4 4 4 0 Stannin transmembrane Nop14 PF04147.12 OAG16028.1 - 2.8e-237 790.2 38.6 5.7e-184 613.8 22.5 2.2 1 1 1 2 2 2 2 Nop14-like family PBC PF03792.13 OAG16028.1 - 0.03 14.1 0.0 0.03 14.1 0.0 3.4 4 1 0 4 4 4 0 PBC domain Vps53_N PF04100.12 OAG16030.1 - 3e-107 358.9 4.6 7.5e-107 357.6 4.6 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 OAG16030.1 - 8.8e-09 35.1 5.0 1.9e-08 33.9 5.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 OAG16030.1 - 3.1e-05 23.9 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 OAG16030.1 - 0.0024 17.9 4.8 0.018 15.2 3.7 3.0 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 OAG16030.1 - 0.0031 16.1 4.5 0.0031 16.1 4.5 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 APG6_N PF17675.1 OAG16030.1 - 0.007 16.9 3.4 0.02 15.4 3.4 1.9 1 0 0 1 1 1 1 Apg6 coiled-coil region VPS53_C PF16854.5 OAG16030.1 - 0.025 14.4 0.2 0.15 11.9 0.0 2.3 2 1 1 3 3 3 0 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 OAG16030.1 - 0.03 13.2 4.9 0.058 12.3 4.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein MitMem_reg PF13012.6 OAG16030.1 - 0.039 14.4 3.9 0.16 12.4 0.0 3.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Baculo_PEP_C PF04513.12 OAG16030.1 - 0.25 11.4 6.1 0.37 10.8 4.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 OAG16030.1 - 0.25 9.9 1.4 0.41 9.2 1.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Allexi_40kDa PF05549.11 OAG16030.1 - 0.26 10.7 3.2 0.29 10.6 1.7 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF5339 PF17274.2 OAG16030.1 - 0.82 10.6 3.6 31 5.5 3.6 2.9 1 1 0 1 1 1 0 Family of unknown function (DUF5339) Glyco_hydro_18 PF00704.28 OAG16031.1 - 1e-71 242.2 0.0 1.2e-71 242.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Comm PF15957.5 OAG16031.1 - 0.12 12.7 0.0 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Commissureless zf-CCCH PF00642.24 OAG16032.1 - 5.4e-21 74.0 37.3 3.8e-06 26.7 0.2 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG16032.1 - 8.3e-16 57.5 43.1 2.2e-06 27.5 1.8 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAG16032.1 - 5.1e-13 49.7 27.3 0.00029 21.5 0.5 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAG16032.1 - 2.1e-09 36.9 40.2 0.00012 21.8 0.5 5.3 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OAG16032.1 - 3.9e-05 23.8 8.1 3.9e-05 23.8 8.1 3.1 1 1 2 3 3 3 2 Zinc-finger containing family Glucos_trans_II PF14264.6 OAG16033.1 - 0.025 13.9 2.2 0.036 13.4 2.2 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII SLATT_fungal PF18142.1 OAG16035.1 - 0.47 10.4 1.5 1.5 8.8 0.5 2.2 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain AA_permease PF00324.21 OAG16037.1 - 3.3e-125 418.4 45.7 4.1e-125 418.1 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG16037.1 - 6.4e-29 101.0 48.4 8.8e-29 100.6 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 OAG16037.1 - 0.91 9.3 2.7 0.79 9.5 0.4 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 Glyco_hydro_88 PF07470.13 OAG16038.1 - 5.9e-14 51.9 0.1 1.2e-13 50.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 TLP1_add_C PF18313.1 OAG16039.1 - 3.4e-31 107.0 0.0 9.4e-31 105.6 0.0 1.8 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Nup54 PF13874.6 OAG16039.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Sec10 PF07393.11 OAG16040.1 - 2.7e-195 650.9 0.0 3.4e-195 650.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 OAG16040.1 - 0.025 14.5 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 MarR family Prenyltransf PF01255.19 OAG16041.1 - 2.1e-05 24.1 0.0 0.00022 20.8 0.0 2.0 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 OAG16041.1 - 0.02 15.3 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Ribosomal_S19 PF00203.21 OAG16042.1 - 2.3e-32 110.7 0.3 3e-32 110.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 OAG16043.1 - 1.3e-25 89.8 12.3 1.6e-25 89.5 12.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 OAG16043.1 - 0.043 13.8 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain SPT2 PF08243.11 OAG16044.1 - 1.2e-07 32.3 12.9 2.4e-07 31.3 12.9 1.5 1 0 0 1 1 1 1 SPT2 chromatin protein Ank_2 PF12796.7 OAG16045.1 - 0.016 15.8 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Rpn9_C PF18261.1 OAG16045.1 - 0.12 11.9 0.2 0.3 10.7 0.2 1.6 1 0 0 1 1 1 0 Rpn9 C-terminal helix Arylsulfotran_2 PF14269.6 OAG16049.1 - 5.9e-61 206.4 3.7 7.9e-61 206.0 3.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG16049.1 - 1.4e-16 60.4 1.6 2.5e-15 56.3 1.6 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF202 PF02656.15 OAG16050.1 - 3.4e-17 62.6 1.2 3.4e-17 62.6 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TssN PF17555.2 OAG16050.1 - 1.3 8.3 5.1 2.2 7.6 3.8 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssN Cation_efflux PF01545.21 OAG16051.1 - 4.8e-51 173.3 15.5 2.3e-50 171.1 15.5 1.8 1 1 0 1 1 1 1 Cation efflux family PTR2 PF00854.21 OAG16052.1 - 2.1e-92 310.0 3.6 5e-92 308.8 3.6 1.5 1 1 0 1 1 1 1 POT family DUF3040 PF11239.8 OAG16052.1 - 8.3 6.8 7.5 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Complex1_49kDa PF00346.19 OAG16056.1 - 6.5e-124 412.4 0.0 9.2e-124 411.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAG16056.1 - 0.0072 15.3 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 OAG16057.1 - 2e-24 86.1 0.0 3.8e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG16057.1 - 8e-21 73.2 0.0 1.8e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ATP-synt PF00231.19 OAG16059.1 - 2.2e-77 260.5 4.0 2.7e-77 260.2 4.0 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I PF01028.20 OAG16060.1 - 1.8e-97 325.1 5.0 1.8e-97 325.1 5.0 2.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 OAG16060.1 - 1.7e-96 321.8 5.4 1.7e-96 321.8 5.4 3.8 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 OAG16060.1 - 3.1e-34 116.7 1.2 1.2e-33 114.8 1.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Epimerase PF01370.21 OAG16061.1 - 1.3e-13 50.9 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG16061.1 - 7.6e-09 35.1 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG16061.1 - 0.091 11.8 0.0 0.27 10.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mt_ATP-synt_B PF05405.14 OAG16062.1 - 1.5e-49 167.8 6.1 1.9e-49 167.4 6.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CBF PF03914.17 OAG16063.1 - 8.9e-36 123.5 0.3 3.3e-35 121.6 0.1 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DPPIV_rep PF18811.1 OAG16063.1 - 0.69 9.9 4.7 2.8 8.0 0.2 3.3 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Sdh5 PF03937.16 OAG16063.1 - 2.3 8.2 4.9 13 5.8 0.5 3.3 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase PIR PF00399.19 OAG16064.1 - 1.1e-05 24.8 6.4 1.1e-05 24.8 6.4 2.3 2 0 0 2 2 2 1 Yeast PIR protein repeat Sugar_tr PF00083.24 OAG16065.1 - 9.2e-26 90.7 18.7 6.9e-23 81.2 18.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16065.1 - 6.5e-08 31.9 34.4 8.7e-06 24.9 11.1 3.3 1 1 1 3 3 3 2 Major Facilitator Superfamily CDC45 PF02724.14 OAG16067.1 - 0.63 8.3 8.1 0.58 8.4 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAG16067.1 - 1.8 7.9 11.7 1.9 7.8 11.7 1.1 1 0 0 1 1 1 0 SDA1 Glyco_transf_34 PF05637.12 OAG16069.1 - 2.5e-64 217.3 1.3 3.7e-64 216.7 1.3 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family CPSase_L_D2 PF02786.17 OAG16071.1 - 4.3e-107 356.4 0.0 4.4e-81 271.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAG16071.1 - 7.6e-42 142.5 0.1 1.9e-41 141.2 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAG16071.1 - 1.8e-18 66.7 0.0 3.5e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAG16071.1 - 3.5e-17 62.6 0.2 1.7e-09 37.6 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OAG16071.1 - 1e-10 41.4 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 OAG16071.1 - 3.8e-06 26.6 0.0 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 OAG16071.1 - 3.7e-05 23.3 0.0 0.032 13.7 0.1 3.2 2 1 1 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 OAG16071.1 - 0.00036 20.4 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SNase PF00565.17 OAG16072.1 - 2.2e-25 89.2 0.8 3.9e-25 88.4 0.8 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Amino_oxidase PF01593.24 OAG16074.1 - 1.2e-84 285.2 0.1 3.9e-70 237.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 OAG16074.1 - 1.1e-14 54.5 0.0 2.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 OAG16074.1 - 4.6e-09 36.4 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG16074.1 - 0.00015 21.4 0.1 0.00044 19.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box PF00505.19 OAG16074.1 - 0.00063 20.1 1.6 0.0013 19.1 0.2 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 OAG16074.1 - 0.00081 18.7 0.1 0.0028 17.0 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG16074.1 - 0.0024 17.9 0.5 0.98 9.4 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding HMG_box_2 PF09011.10 OAG16074.1 - 0.0065 17.0 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain UCH PF00443.29 OAG16075.1 - 2.3e-57 194.4 0.0 4.6e-57 193.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG16075.1 - 8.9e-27 94.5 0.5 9.2e-21 74.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OAG16075.1 - 0.00094 18.7 2.1 0.015 14.8 1.0 2.5 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase MYCBPAP PF14646.6 OAG16075.1 - 0.53 9.2 12.0 0.14 11.1 6.7 2.4 3 0 0 3 3 3 0 MYCBP-associated protein family Synaphin PF05835.12 OAG16075.1 - 2.7 8.2 17.8 0.023 15.0 9.1 1.9 2 0 0 2 2 2 0 Synaphin protein TFIIS_M PF07500.14 OAG16076.1 - 5.2e-30 104.2 0.8 5.2e-30 104.2 0.8 2.4 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAG16076.1 - 1.4e-17 63.3 8.6 2.2e-17 62.6 8.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAG16076.1 - 1.6e-13 50.5 2.4 5.2e-13 48.8 0.7 2.6 3 0 0 3 3 3 1 TFIIS helical bundle-like domain zf-CHY PF05495.12 OAG16076.1 - 0.028 14.9 2.5 0.071 13.6 2.5 1.7 1 1 0 1 1 1 0 CHY zinc finger Evr1_Alr PF04777.13 OAG16076.1 - 0.19 12.2 1.7 0.42 11.1 1.7 1.6 1 0 0 1 1 1 0 Erv1 / Alr family NuA4 PF09340.10 OAG16077.1 - 3e-26 91.1 1.0 3.2e-26 91.0 0.1 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 zf-C2H2 PF00096.26 OAG16078.1 - 4e-10 39.6 11.5 1.5e-05 25.2 4.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG16078.1 - 1e-08 35.2 12.8 5.1e-05 23.5 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG16078.1 - 3.7e-07 30.4 10.4 0.00062 20.4 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAG16078.1 - 7.6e-06 26.1 1.2 1.9e-05 24.9 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG16078.1 - 0.00014 21.8 2.1 0.00014 21.8 2.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG16078.1 - 0.00072 19.8 5.0 0.001 19.3 2.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAG16078.1 - 0.07 13.5 2.0 0.088 13.1 1.0 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OAG16078.1 - 0.2 11.4 8.3 1.1 9.1 0.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAG16078.1 - 0.31 11.0 5.2 4.4 7.3 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 OAG16078.1 - 2.3 8.3 5.2 0.84 9.7 0.9 2.2 2 0 0 2 2 2 0 BED zinc finger HATPase_c PF02518.26 OAG16079.1 - 2.6e-31 108.4 0.1 5.3e-31 107.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG16079.1 - 4.2e-21 74.7 0.3 2.6e-20 72.2 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAG16079.1 - 2.4e-20 72.8 0.1 2.6e-19 69.4 0.0 2.7 3 0 0 3 3 3 1 Response regulator receiver domain PAS_9 PF13426.7 OAG16079.1 - 4.5e-18 65.4 0.1 1e-07 32.2 0.0 4.7 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 OAG16079.1 - 7.2e-17 61.5 1.4 3e-16 59.5 1.4 2.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG16079.1 - 6.5e-16 58.6 2.4 7.7e-06 26.1 0.1 4.8 4 1 0 4 4 4 3 PAS fold PAS PF00989.25 OAG16079.1 - 4.8e-15 55.5 0.0 1.1e-06 28.6 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 OAG16079.1 - 4.2e-06 26.6 0.1 0.22 11.6 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_10 PF13596.6 OAG16079.1 - 0.00063 20.3 0.3 0.84 10.3 0.2 3.0 3 0 0 3 3 3 2 PAS domain HATPase_c_3 PF13589.6 OAG16079.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1835 PF08874.10 OAG16079.1 - 0.2 11.8 2.2 3.2 8.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1835) Yos1 PF08571.10 OAG16080.1 - 1.3e-32 111.9 0.3 1.4e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Yos1-like VRR_NUC PF08774.11 OAG16081.1 - 2.1e-21 76.0 0.0 5.7e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain FANCI_S1-cap PF14674.6 OAG16081.1 - 0.027 14.6 1.0 0.068 13.3 1.0 1.7 1 0 0 1 1 1 0 FANCI solenoid 1 cap KleE PF17394.2 OAG16083.1 - 2.5 8.4 7.4 0.23 11.7 1.9 2.1 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Wzy_C PF04932.15 OAG16083.1 - 8.4 6.0 9.8 0.24 11.0 3.4 1.9 2 1 0 2 2 2 0 O-Antigen ligase Mito_carr PF00153.27 OAG16086.1 - 4.6e-62 206.0 0.8 3.8e-21 74.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OAG16086.1 - 8.8e-13 48.6 9.2 1.5e-12 47.9 0.2 3.1 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF1925 PF09094.11 OAG16086.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Cgr1 PF03879.14 OAG16087.1 - 3e-31 108.0 34.4 3.3e-31 107.8 34.4 1.0 1 0 0 1 1 1 1 Cgr1 family eIF3_subunit PF08597.10 OAG16087.1 - 0.54 10.1 20.0 0.6 10.0 20.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2207 PF09972.9 OAG16088.1 - 0.17 10.6 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HOOK PF05622.12 OAG16088.1 - 0.21 9.7 6.6 0.29 9.2 6.6 1.1 1 0 0 1 1 1 0 HOOK protein SelP_N PF04592.14 OAG16088.1 - 0.7 9.2 12.3 1.3 8.4 12.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prominin PF05478.11 OAG16088.1 - 0.89 7.4 2.3 0.9 7.4 0.4 1.8 1 1 1 2 2 2 0 Prominin TRPM_tetra PF16519.5 OAG16088.1 - 1.2 9.3 3.5 2.5 8.3 0.2 2.8 3 0 0 3 3 3 0 Tetramerisation domain of TRPM ZapB PF06005.12 OAG16088.1 - 2.4 8.6 7.2 2.1 8.8 1.5 2.6 2 1 1 3 3 3 0 Cell division protein ZapB ADH_N PF08240.12 OAG16089.1 - 1.4e-06 28.1 0.2 3.7e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG16089.1 - 0.0023 17.9 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFA PF04828.14 OAG16090.1 - 1.9e-05 24.9 2.8 1.9e-05 24.9 2.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme SF3b1 PF08920.10 OAG16091.1 - 1.2e-21 77.4 10.0 1.9e-20 73.5 10.0 2.6 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 OAG16091.1 - 1.2e-12 48.0 12.6 0.31 11.4 0.0 8.0 5 1 2 8 8 8 6 HEAT repeats HEAT PF02985.22 OAG16091.1 - 2.3e-12 46.0 7.7 0.0013 18.8 0.1 9.2 10 0 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.6 OAG16091.1 - 3.7e-12 46.5 6.5 0.001 19.5 0.0 7.0 7 1 0 7 7 7 3 HEAT-like repeat Cnd1 PF12717.7 OAG16091.1 - 1.1e-08 35.2 5.9 0.18 11.8 0.0 6.6 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG16091.1 - 1.2e-06 29.1 3.3 0.35 11.5 0.0 6.0 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAG16091.1 - 3.9e-06 25.7 1.6 0.36 9.3 0.0 3.5 2 1 1 3 3 3 3 Adaptin N terminal region NUC173 PF08161.12 OAG16091.1 - 0.00048 19.8 0.3 1.9 8.1 0.0 5.0 4 1 2 6 6 6 1 NUC173 domain UNC45-central PF11701.8 OAG16091.1 - 0.00076 19.5 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 OAG16091.1 - 0.0023 17.5 0.1 1 8.9 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal DUF3385 PF11865.8 OAG16091.1 - 0.0025 17.7 5.3 0.053 13.4 0.2 4.4 4 1 0 5 5 5 1 Domain of unknown function (DUF3385) UME PF08064.13 OAG16091.1 - 0.0051 16.7 0.1 8.6 6.3 0.0 4.2 5 0 0 5 5 5 1 UME (NUC010) domain CRM1_C PF08767.11 OAG16091.1 - 0.022 14.0 0.1 0.059 12.5 0.1 1.7 1 0 0 1 1 1 0 CRM1 C terminal PBECR5 PF18814.1 OAG16091.1 - 0.57 10.1 4.9 21 4.9 0.0 3.0 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Aldo_ket_red PF00248.21 OAG16094.1 - 8.8e-67 225.4 0.1 9.8e-67 225.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.21 OAG16095.1 - 0.00026 21.0 8.2 0.00055 20.0 8.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG16095.1 - 0.03 14.4 5.1 0.03 14.4 5.1 1.9 1 1 0 1 1 1 0 Basic region leucine zipper DUF1192 PF06698.11 OAG16095.1 - 0.23 11.6 1.8 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SH3BGR PF04908.15 OAG16096.1 - 0.00022 21.3 1.3 0.0018 18.4 0.0 3.1 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glyco_transf_34 PF05637.12 OAG16097.1 - 1.8e-17 63.9 0.0 2.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 OAG16097.1 - 0.015 15.2 0.4 0.22 11.5 0.0 2.3 1 1 1 2 2 2 0 Nucleotide-diphospho-sugar transferase BRO1 PF03097.18 OAG16098.1 - 1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 BRO1-like domain NDUFB10 PF10249.9 OAG16099.1 - 0.00093 19.7 0.0 0.0011 19.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 OAG16099.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase MFS_1 PF07690.16 OAG16101.1 - 4.2e-53 180.5 50.8 1.7e-51 175.2 51.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG16101.1 - 2e-19 69.5 13.6 2e-19 69.5 13.6 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG16101.1 - 3.3e-15 55.9 6.8 3.3e-15 55.9 6.8 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter DUF1752 PF08550.10 OAG16102.1 - 3.7e-09 36.3 2.8 8.2e-09 35.1 2.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Calreticulin PF00262.18 OAG16103.1 - 2.1e-171 569.7 16.9 2.1e-171 569.7 16.9 2.0 2 0 0 2 2 2 1 Calreticulin family DUF1911 PF08929.10 OAG16103.1 - 0.012 16.4 0.0 0.033 15.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Aldedh PF00171.22 OAG16104.1 - 1.3e-138 462.4 0.7 1.5e-138 462.2 0.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.20 OAG16104.1 - 0.035 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase II DUF2406 PF10295.9 OAG16106.1 - 2.4e-27 95.4 0.8 3.2e-26 91.8 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 OAG16107.1 - 1.2e-14 54.2 10.7 1.6e-14 53.7 10.7 1.2 1 0 0 1 1 1 1 VMA21-like domain TMEM100 PF16311.5 OAG16107.1 - 0.08 12.5 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 SNF2_N PF00176.23 OAG16108.1 - 6e-52 176.5 1.8 1.1e-51 175.7 1.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG16108.1 - 6.2e-21 74.8 0.1 3.6e-17 62.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAG16108.1 - 2.4e-10 40.7 0.0 5.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG16108.1 - 0.0011 18.2 0.1 0.0024 17.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 OAG16108.1 - 0.025 14.2 0.1 0.22 11.1 0.0 2.5 2 0 0 2 2 2 0 DEAD_2 BKACE PF05853.12 OAG16108.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme AA_permease_2 PF13520.6 OAG16109.1 - 9.1e-62 209.3 47.1 1.2e-61 208.9 47.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG16109.1 - 9.2e-18 64.1 38.9 1.2e-17 63.7 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.14 OAG16111.1 - 1.7e-11 43.9 0.0 1.2e-05 24.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG16111.1 - 4e-10 39.4 0.0 0.002 17.5 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG16111.1 - 3.1e-09 36.4 0.0 0.00034 19.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG16111.1 - 4.7e-06 26.4 0.3 0.15 11.6 0.0 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG16111.1 - 0.00028 20.2 0.0 0.021 14.1 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAG16111.1 - 0.00062 20.0 0.1 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG16111.1 - 0.00069 18.4 0.0 0.003 16.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG16111.1 - 0.00097 18.3 0.0 0.003 16.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG16111.1 - 0.0013 19.3 0.0 5.6 7.6 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG16111.1 - 0.0079 15.9 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 OAG16111.1 - 0.0086 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG16111.1 - 0.036 14.1 1.3 0.28 11.2 0.3 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 OAG16111.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mito_carr PF00153.27 OAG16112.1 - 1.3e-58 194.9 3.8 6.1e-20 71.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.6 OAG16112.1 - 0.11 12.7 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation PT-VENN PF04829.13 OAG16112.1 - 1.2 9.3 4.6 21 5.3 0.1 3.4 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Serine_protease PF18405.1 OAG16112.1 - 1.5 7.9 7.5 6.8 5.8 0.2 3.2 2 2 1 4 4 4 0 Gammaproteobacterial serine protease DUF917 PF06032.12 OAG16113.1 - 4.7e-127 423.6 0.5 4.7e-127 423.6 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OAG16113.1 - 2.9e-30 105.5 1.0 1.1e-26 93.8 0.2 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG16113.1 - 3.6e-13 49.6 5.1 9.2e-12 45.0 0.1 3.1 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OAG16113.1 - 0.0007 18.3 1.9 0.00086 18.0 0.0 1.9 2 0 0 2 2 2 1 MutL protein StbA PF06406.11 OAG16113.1 - 0.036 13.3 0.0 7.7 5.6 0.0 2.5 2 1 0 2 2 2 0 StbA protein Methyltransf_16 PF10294.9 OAG16114.1 - 2.3e-18 66.5 0.0 3.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OAG16114.1 - 0.00033 21.3 0.0 0.0006 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG16114.1 - 0.0011 18.6 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG16114.1 - 0.016 15.9 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAG16114.1 - 0.03 13.7 0.1 0.06 12.7 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAG16114.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG16114.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 OAG16115.1 - 2.4e-86 290.4 24.2 3e-86 290.1 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16115.1 - 5.1e-17 61.8 19.9 5.1e-17 61.8 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 OAG16116.1 - 1.3e-71 241.6 0.0 1.6e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OAG16116.1 - 0.00025 21.8 0.7 0.0058 17.4 0.7 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OAG16116.1 - 0.0019 17.9 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAG16116.1 - 0.0043 15.7 0.0 0.007 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 OAG16116.1 - 0.0052 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 OAG16116.1 - 0.013 14.9 0.0 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF4994 PF16385.5 OAG16116.1 - 0.02 14.8 0.5 0.05 13.5 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF2336 PF10098.9 OAG16116.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Zn_clus PF00172.18 OAG16117.1 - 3.2e-08 33.6 5.5 9.5e-08 32.1 5.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG16118.1 - 3.5e-13 50.1 0.0 7.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SCP2 PF02036.17 OAG16119.1 - 4.6e-23 81.6 0.3 5.3e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAG16119.1 - 6.9e-05 23.1 0.2 8.3e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF4115 PF13464.6 OAG16119.1 - 0.086 13.0 0.2 2.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4115) F-box PF00646.33 OAG16120.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 F-box domain Arrestin_N PF00339.29 OAG16121.1 - 6.7e-12 45.7 0.1 1.3e-10 41.5 0.1 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG16121.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus V-ATPase_G PF03179.15 OAG16123.1 - 3.4e-32 111.1 16.6 3.9e-32 110.9 16.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 OAG16123.1 - 0.031 14.3 11.0 0.042 13.8 11.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF3552 PF12072.8 OAG16123.1 - 0.048 13.1 18.1 0.1 12.0 18.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DXP_reductoisom PF02670.16 OAG16123.1 - 0.15 12.8 2.7 0.16 12.7 2.1 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ATP-synt_B PF00430.18 OAG16123.1 - 0.18 11.9 18.2 0.72 9.9 17.0 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 OAG16123.1 - 0.28 11.6 14.1 0.43 11.0 14.1 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RGS-like PF09128.11 OAG16123.1 - 0.32 10.7 5.6 0.38 10.5 5.6 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain OmpH PF03938.14 OAG16123.1 - 0.48 10.8 15.7 0.65 10.3 15.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP11 PF06644.11 OAG16123.1 - 1.3 8.8 11.5 1.6 8.5 11.5 1.1 1 0 0 1 1 1 0 ATP11 protein HAUS6_N PF14661.6 OAG16123.1 - 2.3 7.7 9.1 2.8 7.4 9.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SAPS PF04499.15 OAG16123.1 - 2.8 6.6 9.5 3.2 6.4 9.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 OAG16123.1 - 5.3 6.3 9.4 6.3 6.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 OAG16123.1 - 8.4 7.1 10.3 83 3.9 10.3 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PET117 PF15786.5 OAG16124.1 - 6.1e-25 87.3 1.7 6.9e-25 87.1 1.7 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Tic110 PF16940.5 OAG16124.1 - 0.035 12.6 0.4 0.042 12.4 0.4 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Cys_rich_VLP PF14194.6 OAG16126.1 - 0.16 12.1 2.8 0.31 11.2 2.8 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP AMPK1_CBM PF16561.5 OAG16127.1 - 1.9e-05 24.8 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycoprotein PF03409.15 OAG16127.1 - 0.23 10.2 2.2 0.16 10.8 0.3 1.6 2 0 0 2 2 2 0 Transmembrane glycoprotein Fmp27 PF10344.9 OAG16127.1 - 8.4 4.3 8.0 5.4 5.0 4.1 1.9 2 0 0 2 2 2 0 Mitochondrial protein from FMP27 ADIP PF11559.8 OAG16128.1 - 5e-43 146.8 12.7 5e-43 146.8 12.7 1.8 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 OAG16128.1 - 0.00019 21.0 10.8 0.00019 21.0 10.8 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 5 PKcGMP_CC PF16808.5 OAG16128.1 - 0.02 14.7 2.3 0.34 10.8 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RPW8 PF05659.11 OAG16128.1 - 0.061 13.0 3.1 0.073 12.8 0.4 2.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lipoprotein_6 PF01441.19 OAG16128.1 - 0.13 12.2 1.2 0.26 11.3 1.2 1.4 1 0 0 1 1 1 0 Lipoprotein SHE3 PF17078.5 OAG16128.1 - 0.15 11.8 11.5 0.57 9.9 11.5 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF641 PF04859.12 OAG16128.1 - 0.2 12.0 12.1 3.4 8.0 9.2 3.2 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 OAG16128.1 - 0.37 10.0 2.3 0.74 9.0 2.3 1.6 1 0 0 1 1 1 0 TMPIT-like protein Tup_N PF08581.10 OAG16128.1 - 0.48 10.8 11.4 0.072 13.4 1.4 4.0 3 2 1 5 5 5 0 Tup N-terminal Spc7 PF08317.11 OAG16128.1 - 0.6 8.9 13.2 0.12 11.2 7.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FAP206 PF12018.8 OAG16128.1 - 1 8.8 4.9 3.1 7.3 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function Baculo_PEP_C PF04513.12 OAG16128.1 - 1.3 9.1 10.4 1.1 9.2 3.4 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 OAG16128.1 - 1.5 8.6 9.4 2.8 7.8 8.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Nup88 PF10168.9 OAG16128.1 - 1.7 6.4 13.6 3.5 5.3 0.1 2.1 2 0 0 2 2 2 0 Nuclear pore component DUF2514 PF10721.9 OAG16128.1 - 2.9 7.9 16.3 0.43 10.6 11.8 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2514) DUF2570 PF10828.8 OAG16128.1 - 3.2 7.6 6.2 8.5 6.2 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) BORCS6 PF10157.9 OAG16128.1 - 4.9 7.4 9.7 1.5 9.1 0.0 2.9 3 1 0 3 3 3 0 BLOC-1-related complex sub-unit 6 Mto2_bdg PF12808.7 OAG16128.1 - 6.3 7.2 16.5 3.4 8.1 3.1 3.8 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FUSC PF04632.12 OAG16128.1 - 6.3 5.2 6.8 15 4.0 6.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 OAG16128.1 - 9.1 5.8 7.5 1.3 8.5 1.8 2.3 2 1 1 3 3 3 0 fzo-like conserved region FAD_binding_4 PF01565.23 OAG16129.1 - 2.5e-18 66.1 2.3 4e-18 65.5 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.20 OAG16130.1 - 3.1e-33 115.5 0.1 5.2e-33 114.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG16130.1 - 5.8e-12 45.4 0.0 1.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG16130.1 - 5.3e-08 33.7 0.1 8.1e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG16130.1 - 0.00074 19.6 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 OAG16130.1 - 0.02 14.6 0.0 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 OAG16130.1 - 0.032 12.9 0.0 0.9 8.1 0.0 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Peptidase_S28 PF05577.12 OAG16130.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Keratin_assoc PF09775.9 OAG16130.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 HATPase_c PF02518.26 OAG16131.1 - 4.5e-22 78.7 0.1 1.6e-21 76.9 0.0 2.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG16131.1 - 1.4e-13 51.0 0.0 1.8e-10 41.0 0.1 2.7 1 1 1 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 OAG16131.1 - 5.2e-09 36.0 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain C166 PF17615.2 OAG16132.1 - 8.4e-33 113.7 9.1 1.1e-32 113.4 9.1 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 OAG16132.1 - 4.3e-07 30.4 1.1 4.2e-06 27.2 0.1 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Meth_synt_2 PF01717.18 OAG16133.1 - 4.1e-14 52.6 0.0 9.2e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG16133.1 - 0.00048 19.7 0.0 0.028 13.9 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Kelch_4 PF13418.6 OAG16135.1 - 3.6e-28 97.3 6.0 1.9e-11 43.8 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG16135.1 - 5.9e-24 83.8 4.7 9.8e-07 28.9 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG16135.1 - 8.2e-16 57.7 7.1 0.0064 16.8 0.1 5.6 3 2 2 5 5 5 5 Kelch motif Kelch_1 PF01344.25 OAG16135.1 - 4.1e-13 48.7 3.1 0.0023 17.5 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OAG16135.1 - 1.3e-08 34.6 3.4 0.0057 16.6 0.0 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OAG16135.1 - 2.2e-06 27.4 8.2 0.064 13.3 0.5 5.4 5 1 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 OAG16135.1 - 0.057 13.9 0.2 8.8 7.0 0.1 3.1 2 0 0 2 2 2 0 PQQ-like domain p450 PF00067.22 OAG16136.1 - 4.1e-78 263.2 0.0 5e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rotavirus_VP3 PF06929.11 OAG16136.1 - 0.08 11.2 0.1 0.12 10.6 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Glyco_hydro_16 PF00722.21 OAG16137.1 - 5.1e-18 65.2 1.3 1.1e-17 64.1 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ATPase_gene1 PF09527.10 OAG16137.1 - 0.015 15.5 2.5 0.15 12.3 0.4 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4097 PF13349.6 OAG16137.1 - 0.067 12.5 0.7 0.097 12.0 0.7 1.2 1 0 0 1 1 1 0 Putative adhesin Glyco_trans_2_3 PF13632.6 OAG16139.1 - 1.9e-52 178.1 1.1 1.9e-52 178.1 1.1 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG16139.1 - 0.00011 22.1 0.0 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG16139.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG16139.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Herpes_ICP4_N PF03584.15 OAG16139.1 - 0.2 11.5 0.0 9.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region Het-C PF07217.11 OAG16140.1 - 3.5e-238 791.7 0.0 4.5e-238 791.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Oxidored_FMN PF00724.20 OAG16141.1 - 4.4e-86 289.2 0.0 5e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_18 PF00704.28 OAG16142.1 - 3.6e-58 197.7 0.2 4.2e-58 197.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG16142.1 - 3.3e-08 33.9 43.0 1e-06 29.1 13.2 3.0 2 0 0 2 2 2 2 Chitin recognition protein LysM PF01476.20 OAG16144.1 - 0.084 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 LysM domain Chitin_bind_1 PF00187.19 OAG16145.1 - 1.6e-38 130.9 249.5 6.1e-06 26.6 18.0 10.0 8 1 0 9 9 9 9 Chitin recognition protein Peroxidase_2 PF01328.17 OAG16146.1 - 3.9e-44 151.4 0.0 5.8e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 CAMSAP_CKK PF08683.11 OAG16148.1 - 0.11 12.7 0.0 7.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated DUF2408 PF10303.9 OAG16150.1 - 0.099 13.2 0.1 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) GAF PF01590.26 OAG16152.1 - 0.1 13.2 0.0 0.27 11.9 0.0 1.7 2 0 0 2 2 2 0 GAF domain Aldo_ket_red PF00248.21 OAG16153.1 - 1.1e-58 198.8 0.0 1.4e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG16154.1 - 7.7e-29 100.7 65.8 1.6e-16 60.2 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ustilago_mating PF05722.12 OAG16155.1 - 0.083 12.4 0.0 0.083 12.4 0.0 1.0 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Fringe PF02434.16 OAG16157.1 - 3.3e-11 43.1 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_3 PF08277.12 OAG16157.1 - 0.021 14.7 0.2 0.05 13.4 0.2 1.6 1 0 0 1 1 1 0 PAN-like domain HET PF06985.11 OAG16158.1 - 4.9e-19 69.1 0.0 8.7e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG16159.1 - 5.6e-23 81.9 0.0 1e-22 81.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) L6_membrane PF05805.12 OAG16160.1 - 0.09 12.3 0.3 0.12 12.0 0.3 1.3 1 1 0 1 1 1 0 L6 membrane protein DIM PF08194.12 OAG16161.1 - 0.091 13.0 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 DIM protein GMC_oxred_N PF00732.19 OAG16162.1 - 2.4e-49 168.3 0.0 4.7e-49 167.4 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG16162.1 - 5.8e-38 130.7 0.0 9.5e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG16162.1 - 7.4e-06 25.2 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG16162.1 - 0.00015 21.9 0.0 0.00047 20.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG16162.1 - 0.00059 20.3 0.2 0.2 12.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG16162.1 - 0.0009 18.4 0.0 0.22 10.6 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG16162.1 - 0.0015 17.8 0.0 0.0078 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG16162.1 - 0.0019 17.8 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG16162.1 - 0.003 16.8 0.1 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 OAG16162.1 - 0.037 12.9 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 OAG16162.1 - 0.043 13.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.22 OAG16163.1 - 6.4e-159 529.3 0.2 8.1e-159 529.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 OAG16164.1 - 0 1016.9 0.8 1.2e-77 261.3 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 OAG16164.1 - 4e-242 803.7 0.0 8.1e-85 285.2 0.2 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 OAG16164.1 - 1e-52 176.3 8.7 1.4e-12 47.7 0.2 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG16164.1 - 3.8e-19 69.4 5.5 0.0013 19.7 0.0 7.0 6 1 1 7 7 7 5 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 OAG16164.1 - 6.3e-15 55.4 0.0 2.9e-05 23.9 0.0 3.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16164.1 - 8e-14 52.1 0.0 2.9e-05 24.7 0.0 3.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG16164.1 - 2.4e-12 47.5 0.0 2.8e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAG16164.1 - 4.9e-12 46.3 0.0 0.00024 21.7 0.0 3.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OAG16164.1 - 9.6e-09 35.2 0.0 0.00028 20.7 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 OAG16164.1 - 0.00037 20.3 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 Lysine methyltransferase ASC PF00858.24 OAG16164.1 - 0.052 12.5 0.0 7.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel RrnaAD PF00398.20 OAG16164.1 - 0.099 11.7 0.0 14 4.6 0.0 2.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase NTS_2 PF15448.6 OAG16164.1 - 0.13 12.7 0.0 0.52 10.7 0.0 2.0 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein p450 PF00067.22 OAG16165.1 - 3.9e-13 49.0 0.0 4.3e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Dabb PF07876.12 OAG16167.1 - 4.3e-09 36.9 0.0 2.3e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2235 PF09994.9 OAG16168.1 - 2.1e-87 293.2 0.0 2.8e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BPL_N PF09825.9 OAG16169.1 - 8.5e-149 495.7 0.0 1.1e-148 495.3 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAG16169.1 - 1.8e-22 79.6 0.0 3.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ntox27 PF15531.6 OAG16169.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 27 Glyco_hydro_42M PF08532.10 OAG16169.1 - 0.17 11.3 0.3 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain DUF5580 PF17743.1 OAG16169.1 - 0.26 9.8 1.0 0.38 9.2 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Vps53_N PF04100.12 OAG16169.1 - 0.33 9.9 0.6 0.46 9.4 0.6 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal CHCH PF06747.13 OAG16170.1 - 8.8e-06 25.7 7.3 1.3e-05 25.2 7.3 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAG16170.1 - 0.0023 17.9 1.4 0.049 13.6 0.4 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAG16170.1 - 0.051 13.6 3.6 0.11 12.5 3.6 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GT-D PF08759.11 OAG16170.1 - 0.065 12.9 0.1 0.069 12.8 0.1 1.0 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Oxysterol_BP PF01237.18 OAG16171.1 - 1.2e-65 221.8 7.6 1.3e-63 215.1 7.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein YwhD PF08741.10 OAG16171.1 - 0.071 12.8 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 YwhD family PGM_PMM_I PF02878.16 OAG16172.1 - 1e-32 112.7 0.0 1.5e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAG16172.1 - 1.9e-26 92.5 0.0 3.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAG16172.1 - 6.8e-16 58.8 0.0 1.6e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAG16172.1 - 2.2e-09 37.4 0.0 5.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain XPG_I_2 PF12813.7 OAG16173.1 - 5.6e-46 157.0 0.0 1.3e-45 155.9 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.18 OAG16173.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 XPG I-region Fungal_trans_2 PF11951.8 OAG16175.1 - 4.4e-22 78.4 0.3 6.3e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16175.1 - 0.00055 20.0 9.0 0.00087 19.4 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.10 OAG16176.1 - 8.2e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAG16176.1 - 1.4e-11 44.5 0.1 7.3e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DNA_pol_A_exo1 PF01612.20 OAG16177.1 - 1.1e-10 41.5 0.0 3e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease RSN1_7TM PF02714.15 OAG16178.1 - 5.1e-78 262.2 21.8 1.2e-77 261.0 21.8 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG16178.1 - 1.1e-37 129.9 0.2 1.9e-37 129.2 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG16178.1 - 3.2e-36 124.4 4.2 3.2e-36 124.4 4.2 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport CABS1 PF15367.6 OAG16178.1 - 0.016 14.4 0.2 0.024 13.8 0.2 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 ABC_tran_CTD PF16326.5 OAG16178.1 - 0.23 11.8 0.5 24 5.3 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain PhoR PF11808.8 OAG16178.1 - 0.99 9.9 5.2 1.6 9.2 0.5 3.5 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR MRP-L28 PF09812.9 OAG16179.1 - 7.6e-06 26.2 0.0 2.3e-05 24.6 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 OAG16180.1 - 1.8e-47 160.9 0.0 2.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG16180.1 - 7e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG16180.1 - 3.8e-08 33.0 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG16180.1 - 0.009 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG16180.1 - 0.014 14.7 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG16180.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAG16180.1 - 0.076 12.8 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 OAG16180.1 - 0.15 12.0 0.0 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AAA_16 PF13191.6 OAG16180.1 - 0.18 12.2 0.1 0.43 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAG16180.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 OAG16181.1 - 1.9e-52 178.2 0.1 1.9e-52 178.2 0.1 4.1 3 1 1 4 4 4 1 Salt tolerance down-regulator PGM_PMM_I PF02878.16 OAG16182.1 - 1.4e-19 70.2 0.1 1.1e-08 34.9 0.0 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAG16182.1 - 1.3e-12 47.7 2.2 1.8e-10 40.9 1.1 3.4 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OAG16182.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAG16182.1 - 0.013 16.1 0.9 0.2 12.3 0.3 3.2 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FANCI_S1-cap PF14674.6 OAG16182.1 - 0.2 11.8 0.3 0.95 9.6 0.1 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 cap FAD_binding_3 PF01494.19 OAG16184.1 - 6.8e-23 81.5 0.1 5.9e-22 78.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG16184.1 - 0.0045 17.5 3.2 0.49 11.0 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG16184.1 - 0.0045 16.3 0.5 1 8.6 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG16184.1 - 0.0046 16.2 0.3 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG16184.1 - 0.005 16.2 0.2 0.071 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.10 OAG16184.1 - 0.023 13.8 0.0 0.085 11.9 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 OAG16184.1 - 0.049 13.9 0.1 0.28 11.4 0.1 2.4 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG16184.1 - 0.11 11.5 0.7 1.8 7.6 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein SET PF00856.28 OAG16186.1 - 4.2e-10 40.3 0.0 9.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 SET domain TPR_2 PF07719.17 OAG16186.1 - 2.9e-05 23.8 10.1 0.011 15.8 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAG16186.1 - 0.00049 20.1 0.8 0.0013 18.7 0.8 1.7 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_1 PF00515.28 OAG16186.1 - 0.0016 18.2 11.0 0.37 10.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG16186.1 - 0.035 14.3 1.2 0.13 12.5 1.2 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OAG16186.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.4 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 OAG16186.1 - 0.19 12.5 7.7 0.62 10.8 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG16186.1 - 0.19 12.6 1.8 0.29 12.1 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG16186.1 - 1.5 9.0 4.1 4.5 7.4 0.7 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 OAG16186.1 - 4.3 7.8 4.6 35 4.9 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pec_lyase_C PF00544.19 OAG16188.1 - 5.1e-09 36.0 3.3 1.6e-07 31.1 3.0 2.4 1 1 0 1 1 1 1 Pectate lyase malic PF00390.19 OAG16188.1 - 0.021 14.6 0.4 0.035 13.9 0.4 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Beta_helix PF13229.6 OAG16188.1 - 0.38 10.6 7.1 1.5 8.7 6.2 2.1 1 1 1 2 2 2 0 Right handed beta helix region APH PF01636.23 OAG16189.1 - 5e-11 43.0 0.0 9.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Homeobox_KN PF05920.11 OAG16190.1 - 4.2e-07 29.8 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.6 OAG16190.1 - 0.00014 22.4 17.3 1.2 10.2 1.3 5.0 3 1 1 4 4 4 3 C2H2-type zinc finger HTH_Mga PF08280.11 OAG16190.1 - 0.0059 16.6 0.2 0.011 15.7 0.2 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Homeodomain PF00046.29 OAG16190.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain zf-C2H2 PF00096.26 OAG16190.1 - 0.038 14.5 12.0 1.2 9.8 0.1 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG16190.1 - 0.33 11.3 3.6 13 6.2 0.4 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MSL1_dimer PF16801.5 OAG16190.1 - 0.38 10.6 4.1 0.72 9.7 4.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Homeobox_KN PF05920.11 OAG16191.1 - 4.6e-09 36.0 0.1 1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 OAG16191.1 - 0.0035 17.7 10.9 0.43 11.1 2.3 4.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG16191.1 - 0.0044 17.3 5.5 1.1 9.7 3.4 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG16191.1 - 0.0052 17.5 16.9 0.04 14.8 2.5 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger Ribosomal_L44 PF00935.19 OAG16191.1 - 1.2 9.6 4.4 0.45 11.0 1.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 zf-C2H2_2 PF12756.7 OAG16191.1 - 2.2 8.6 8.7 36 4.8 0.6 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) GMC_oxred_N PF00732.19 OAG16192.1 - 6.6e-31 107.8 0.0 7.8e-28 97.7 0.0 2.9 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG16192.1 - 9.4e-29 100.8 0.1 1.7e-28 100.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG16192.1 - 0.00025 21.2 0.1 0.00064 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG16192.1 - 0.0022 17.3 0.0 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG16192.1 - 0.0026 16.9 0.4 0.015 14.4 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG16192.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG16192.1 - 0.19 10.9 0.2 3.1 7.0 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG16192.1 - 0.21 11.2 0.6 0.45 10.2 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Meth_synt_2 PF01717.18 OAG16193.1 - 1.5e-13 50.7 0.0 1.5e-08 34.3 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG16193.1 - 0.00057 19.5 0.0 0.0053 16.3 0.0 2.4 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain CKS PF01111.19 OAG16193.1 - 0.0052 17.0 0.1 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Epimerase PF01370.21 OAG16194.1 - 1.2e-16 61.0 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG16194.1 - 2.5e-12 46.4 0.0 3.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG16194.1 - 4.3e-09 35.9 0.0 2.7e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG16194.1 - 2.9e-08 33.5 0.1 7.4e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG16194.1 - 7.8e-05 22.3 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 OAG16194.1 - 0.00028 20.9 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG16194.1 - 0.00078 19.4 0.5 0.0011 18.9 0.1 1.7 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 OAG16194.1 - 0.00092 18.7 0.1 0.0041 16.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG16194.1 - 0.0017 17.6 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG16194.1 - 0.03 14.9 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG16194.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NTF2 PF02136.20 OAG16195.1 - 4.1e-32 111.3 0.0 4.6e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAG16195.1 - 0.012 16.0 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Thiolase_N PF00108.23 OAG16196.1 - 1.8e-75 253.7 2.1 2.3e-75 253.3 2.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG16196.1 - 6e-41 138.9 0.4 2.1e-40 137.2 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG16196.1 - 0.00012 21.8 1.3 0.00012 21.8 1.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.8 OAG16197.1 - 6e-11 43.0 11.0 6e-11 43.0 11.0 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.10 OAG16198.1 - 3.6e-76 255.2 0.3 6.6e-76 254.4 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OAG16198.1 - 1.6e-25 89.8 0.4 2.8e-25 88.9 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAG16198.1 - 2.9e-09 36.7 0.1 7.8e-09 35.3 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAG16198.1 - 0.034 13.9 1.1 0.54 10.0 0.1 2.4 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain adh_short PF00106.25 OAG16199.1 - 2.7e-33 115.1 0.0 3.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16199.1 - 4.9e-28 98.3 0.0 3.4e-27 95.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG16199.1 - 9.3e-10 38.7 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 KR domain AAA PF00004.29 OAG16201.1 - 2.3e-17 63.6 0.2 9.2e-16 58.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG16201.1 - 0.00078 19.7 1.3 0.0087 16.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OAG16201.1 - 0.0011 19.4 0.2 0.0035 17.7 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG16201.1 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.11 OAG16201.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 Torsin AAA_30 PF13604.6 OAG16201.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG16201.1 - 0.04 14.1 0.0 0.19 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG16201.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 OAG16201.1 - 0.17 12.2 0.4 1 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 OAG16201.1 - 0.18 11.4 0.2 5.4 6.6 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Serine_rich PF08824.10 OAG16202.1 - 0.0062 16.5 1.5 0.0062 16.5 1.5 2.1 3 0 0 3 3 3 1 Serine rich protein interaction domain Phi-29_GP16_7 PF06720.11 OAG16202.1 - 0.19 11.5 2.0 0.39 10.6 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 CorA PF01544.18 OAG16202.1 - 0.23 10.7 5.1 0.28 10.5 0.1 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein EGF_2 PF07974.13 OAG16203.1 - 7.3 7.1 11.6 33 5.0 11.6 2.1 1 1 0 1 1 1 0 EGF-like domain Chlorosome_CsmC PF11098.8 OAG16205.1 - 0.026 14.5 6.4 0.032 14.2 6.4 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C MIF4G PF02854.19 OAG16206.1 - 3.3e-49 167.4 0.0 7.9e-49 166.2 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAG16206.1 - 9.5e-24 83.4 0.4 3.8e-23 81.5 0.4 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 THRAP3_BCLAF1 PF15440.6 OAG16206.1 - 0.043 12.8 33.3 0.11 11.5 33.3 1.6 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Homeodomain PF00046.29 OAG16207.1 - 2.8e-17 62.3 3.5 4.9e-17 61.5 3.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG16207.1 - 0.026 14.4 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain PBP1_TM PF14812.6 OAG16207.1 - 5.7 7.4 9.4 1.5 9.2 4.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal efThoc1 PF11957.8 OAG16209.1 - 1e-124 416.9 4.2 1.3e-124 416.6 4.2 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Swi3 PF07962.12 OAG16210.1 - 2.9e-30 104.1 0.2 4.3e-30 103.5 0.2 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.12 OAG16211.1 - 4.9e-51 172.6 1.3 7.8e-51 172.0 0.6 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 OAG16211.1 - 1.5e-41 141.4 0.0 2.9e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 OAG16211.1 - 1.2e-22 81.2 0.8 1.9e-22 80.5 0.8 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OAG16211.1 - 1.4e-18 67.2 0.0 3.6e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG16211.1 - 6.8e-07 29.6 0.0 2.8e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG16211.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ins_allergen_rp PF06757.13 OAG16212.1 - 0.033 14.2 0.9 15 5.5 0.0 3.0 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification DUF848 PF05852.11 OAG16212.1 - 0.8 9.8 9.8 0.092 12.8 2.2 2.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Phage_holin_7_1 PF16081.5 OAG16212.1 - 2.5 8.3 4.6 5.4 7.2 0.3 2.7 1 1 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family ECH_2 PF16113.5 OAG16212.1 - 7.3 6.0 11.4 3.2 7.1 7.6 2.0 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 OAG16213.1 - 3.3e-22 79.1 0.0 6.6e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16213.1 - 3.7e-06 26.4 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG16213.1 - 0.0053 16.1 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.11 OAG16215.1 - 1.5e-31 109.7 0.4 2.3e-31 109.1 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aquarius_N PF16399.5 OAG16216.1 - 0 1084.8 0.0 0 1084.3 0.0 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OAG16216.1 - 1.2e-29 103.4 0.0 1.9e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG16216.1 - 3.6e-22 79.4 0.0 1.1e-21 77.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG16216.1 - 1.4e-06 28.2 0.0 0.001 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG16216.1 - 2.4e-06 27.9 0.0 6.3e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG16216.1 - 2.9e-05 24.1 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 OAG16216.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 OAG16216.1 - 0.004 17.6 0.0 0.023 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG16216.1 - 0.0051 17.2 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 OAG16216.1 - 0.024 13.9 0.8 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OAG16216.1 - 0.034 13.7 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 OAG16216.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.17 OAG16216.1 - 0.047 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UvrD_C_2 PF13538.6 OAG16216.1 - 0.092 12.6 0.6 0.22 11.4 0.1 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 OAG16216.1 - 0.12 12.7 0.1 1.7 9.1 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 OAG16216.1 - 0.15 12.3 1.0 0.98 9.7 0.2 2.6 2 1 1 3 3 2 0 AAA domain AAA_5 PF07728.14 OAG16216.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_pol_3_Rpc31 PF11705.8 OAG16216.1 - 3.6 7.8 8.8 10 6.3 8.8 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NADH-u_ox-rdase PF10785.9 OAG16217.1 - 1.2e-27 96.4 0.3 2.1e-27 95.6 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 OAG16217.1 - 5.6e-23 80.7 0.1 8.6e-23 80.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TauD PF02668.16 OAG16218.1 - 1.9e-36 126.3 0.1 2.6e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG16218.1 - 2.1e-09 37.9 0.1 7.6e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 OAG16218.1 - 0.049 12.7 0.0 0.51 9.4 0.0 2.1 2 0 0 2 2 2 0 CsiD AAA PF00004.29 OAG16219.1 - 2.1e-40 138.2 0.0 4.2e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG16219.1 - 2.9e-19 68.8 0.3 5.8e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAG16219.1 - 7.9e-09 35.2 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG16219.1 - 9.7e-05 22.4 0.1 0.00053 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG16219.1 - 0.00014 22.3 1.5 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAG16219.1 - 0.00029 21.0 0.1 0.011 15.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG16219.1 - 0.0003 20.6 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG16219.1 - 0.0014 18.9 1.8 0.082 13.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 OAG16219.1 - 0.0069 15.8 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OAG16219.1 - 0.007 15.8 1.1 0.08 12.4 0.1 2.5 3 0 0 3 3 3 1 PhoH-like protein AAA_33 PF13671.6 OAG16219.1 - 0.0089 16.2 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAG16219.1 - 0.012 14.8 0.6 0.03 13.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLZ PF16526.5 OAG16219.1 - 0.017 15.5 5.6 0.09 13.1 5.6 2.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IstB_IS21 PF01695.17 OAG16219.1 - 0.074 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein JIP_LZII PF16471.5 OAG16219.1 - 0.091 13.0 5.2 0.27 11.5 5.2 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_7 PF12775.7 OAG16219.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG16219.1 - 0.26 11.0 0.0 0.26 11.0 0.0 2.5 3 1 0 3 3 2 0 AAA domain RPN2_C PF18004.1 OAG16219.1 - 3 7.7 8.7 7.5 6.5 8.7 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3419 PF11899.8 OAG16221.1 - 7.3e-151 502.7 0.0 9.5e-151 502.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 OAG16221.1 - 2.3e-11 43.8 0.0 4.6e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16221.1 - 2.7e-07 31.2 0.0 1.8e-05 25.3 0.0 3.5 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG16221.1 - 8.1e-07 29.7 0.0 6.7e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG16221.1 - 2.6e-05 24.8 0.0 0.0025 18.4 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG16221.1 - 4.2e-05 23.4 0.0 0.00017 21.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG16221.1 - 0.0082 15.5 0.0 0.047 13.0 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG16221.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG16221.1 - 0.046 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Rer1 PF03248.13 OAG16222.1 - 2.1e-77 258.7 2.1 2.5e-77 258.5 2.1 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 OAG16223.1 - 4.2e-73 245.7 0.4 4.8e-73 245.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG16223.1 - 2.2e-33 116.2 0.1 4.7e-31 108.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PrpR_N PF06506.11 OAG16223.1 - 0.038 13.6 0.2 0.074 12.6 0.1 1.5 2 0 0 2 2 2 0 Propionate catabolism activator Ferric_reduct PF01794.19 OAG16224.1 - 2.6e-19 69.6 9.5 7.2e-19 68.1 9.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG16224.1 - 6.4e-09 35.9 0.3 7.1e-08 32.5 0.3 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG16224.1 - 3.5e-06 27.2 0.0 0.014 15.5 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Chordopox_A13L PF05961.11 OAG16225.1 - 0.05 13.8 0.1 0.11 12.8 0.0 1.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Tfb2 PF03849.14 OAG16227.1 - 3.5e-131 437.4 0.0 4.4e-131 437.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAG16227.1 - 4.6e-19 68.6 0.0 9.5e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAG16227.1 - 0.00057 20.0 0.0 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dynamin_M PF01031.20 OAG16227.1 - 0.066 12.4 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin central region 4HBT PF03061.22 OAG16228.1 - 3e-13 49.9 0.0 3.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG16228.1 - 0.05 13.7 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Lipase_GDSL_2 PF13472.6 OAG16230.1 - 2.5e-10 41.0 0.1 3.1e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG16230.1 - 1.9e-07 31.2 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase adh_short PF00106.25 OAG16231.1 - 4e-28 98.2 0.1 5.4e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16231.1 - 5.7e-19 68.6 0.1 6.9e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG16231.1 - 6e-07 29.2 0.1 3.6e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG16231.1 - 9.8e-07 28.9 0.1 2e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG16231.1 - 8.8e-05 22.5 0.1 0.00026 20.9 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG16231.1 - 0.00052 19.6 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG16231.1 - 0.0014 18.1 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 OAG16232.1 - 1.6e-25 89.8 0.6 2.4e-25 89.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16232.1 - 9.7e-05 22.4 8.6 0.00016 21.7 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 OAG16233.1 - 1e-06 29.0 15.1 0.1 13.5 4.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG16233.1 - 2.8e-05 24.3 16.5 0.054 14.0 1.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OAG16233.1 - 0.0031 17.2 13.4 0.21 11.4 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 OAG16233.1 - 0.041 14.2 3.2 0.041 14.2 3.2 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4729 PF15866.5 OAG16233.1 - 0.24 10.7 7.9 0.85 8.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) Transpos_assoc PF13963.6 OAG16233.1 - 0.35 11.2 7.3 0.91 9.9 0.9 2.8 2 1 1 3 3 3 0 Transposase-associated domain Sina PF03145.16 OAG16233.1 - 0.96 9.4 7.9 1.9 8.4 8.0 1.4 1 1 0 1 1 1 0 Seven in absentia protein family zf-BED PF02892.15 OAG16233.1 - 1.8 8.7 7.5 2 8.5 0.2 3.2 3 0 0 3 3 3 0 BED zinc finger zf-met2 PF12907.7 OAG16233.1 - 3 8.0 11.0 13 6.0 3.1 3.3 3 0 0 3 3 3 0 Zinc-binding FOXP-CC PF16159.5 OAG16233.1 - 4.2 8.1 7.8 61 4.4 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAG16235.1 - 5.4e-05 23.4 5.9 0.88 10.2 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG16235.1 - 0.053 14.0 3.3 0.34 11.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG16235.1 - 1.8 9.6 4.6 64 4.8 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1304 PF06993.12 OAG16236.1 - 0.00056 19.9 3.2 0.0011 19.0 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Saf_2TM PF18303.1 OAG16236.1 - 0.051 13.2 0.3 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Chromate_transp PF02417.15 OAG16236.1 - 0.071 13.3 5.0 0.1 12.8 5.0 1.1 1 0 0 1 1 1 0 Chromate transporter Zeta_toxin PF06414.12 OAG16236.1 - 0.11 11.8 0.1 0.3 10.3 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin Fumble PF03630.14 OAG16237.1 - 9.2e-142 472.1 0.0 1.2e-141 471.7 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF2256 PF10013.9 OAG16238.1 - 3.8e-06 26.9 3.4 1.1e-05 25.5 3.4 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC5 PF06221.13 OAG16238.1 - 0.15 12.1 0.3 0.28 11.2 0.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-MYND PF01753.18 OAG16238.1 - 5.2 7.3 8.7 0.66 10.1 4.3 1.8 2 0 0 2 2 2 0 MYND finger Myb_DNA-binding PF00249.31 OAG16239.1 - 0.0002 21.5 0.1 0.00047 20.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0016 PF01169.19 OAG16240.1 - 6.3e-41 138.6 26.2 5.4e-21 74.7 11.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 OAG16240.1 - 0.031 14.0 0.1 0.031 14.0 0.1 2.3 2 0 0 2 2 2 0 Putative manganese efflux pump Cyclin_N PF00134.23 OAG16241.1 - 1.2e-14 54.1 0.2 3.2e-14 52.8 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG16241.1 - 0.00078 19.5 0.8 0.034 14.2 0.0 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 OAG16241.1 - 0.0032 17.5 2.5 1.5 8.9 0.4 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Abhydrolase_3 PF07859.13 OAG16242.1 - 2.5e-41 141.9 0.0 4.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG16242.1 - 0.062 12.2 0.0 4.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Steryl acetyl hydrolase Seipin PF06775.14 OAG16245.1 - 8.5e-54 182.7 0.0 1.1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) zf-PARP PF00645.18 OAG16248.1 - 1e-19 71.2 0.2 1e-19 71.2 0.2 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CHZ PF09649.10 OAG16250.1 - 0.0094 15.4 3.3 0.021 14.3 3.3 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ Pex14_N PF04695.13 OAG16251.1 - 5.8e-42 144.0 1.4 5.8e-42 144.0 1.4 2.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BicD PF09730.9 OAG16251.1 - 8.5e-05 21.2 0.1 0.00012 20.7 0.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D V-SNARE_C PF12352.8 OAG16251.1 - 0.027 14.8 1.1 0.044 14.1 0.2 1.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF1043 PF06295.12 OAG16251.1 - 0.057 13.4 1.9 0.14 12.2 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3847 PF12958.7 OAG16251.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) LMBR1 PF04791.16 OAG16251.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 OAG16251.1 - 0.17 11.9 0.0 0.64 10.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) EamA PF00892.20 OAG16251.1 - 0.21 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family Baculo_PEP_C PF04513.12 OAG16251.1 - 0.21 11.6 2.3 9 6.3 0.1 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 OAG16251.1 - 0.23 10.9 2.9 0.35 10.3 2.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 OAG16251.1 - 0.4 8.1 5.5 0.54 7.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.14 OAG16251.1 - 0.81 9.3 6.4 1.6 8.3 6.4 1.5 1 1 0 1 1 1 0 Laminin Domain I DUF3450 PF11932.8 OAG16251.1 - 0.98 8.7 4.6 1.8 7.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3439 PF11921.8 OAG16252.1 - 0.79 9.7 8.1 2.2 8.3 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) 3HCDH_N PF02737.18 OAG16254.1 - 1.1e-51 175.3 0.3 1.5e-51 174.8 0.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG16254.1 - 2.4e-33 114.6 0.0 4.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG16254.1 - 0.00093 19.4 0.1 0.0025 18.0 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OAG16254.1 - 0.0037 16.7 0.3 0.026 13.9 0.1 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG16254.1 - 0.0085 16.4 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FeoC PF09012.10 OAG16254.1 - 0.024 14.7 0.0 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 FeoC like transcriptional regulator UDPG_MGDP_dh_N PF03721.14 OAG16254.1 - 0.031 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LpxI_C PF06230.11 OAG16254.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 LpxI C-terminal domain NAD_Gly3P_dh_N PF01210.23 OAG16254.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TIMELESS PF04821.14 OAG16255.1 - 2.2e-78 263.3 0.0 6.1e-78 261.9 0.0 1.9 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 OAG16255.1 - 2.1e-23 83.3 0.0 2.1e-23 83.3 0.0 4.2 2 1 2 4 4 4 1 Timeless protein C terminal region Ribosomal_S28e PF01200.18 OAG16257.1 - 3.7e-30 103.7 1.4 4.1e-30 103.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Chitin_bind_1 PF00187.19 OAG16258.1 - 4.8e-07 30.1 21.0 4.8e-07 30.1 21.0 2.8 2 1 0 2 2 2 1 Chitin recognition protein TFIIB PF00382.19 OAG16259.1 - 4e-32 110.1 0.4 3.7e-16 58.9 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAG16259.1 - 1.2e-12 47.1 1.3 2.5e-12 46.1 1.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 OAG16259.1 - 2e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain HTH_29 PF13551.6 OAG16259.1 - 0.07 13.2 0.0 8.4 6.5 0.0 3.4 4 0 0 4 4 4 0 Winged helix-turn helix zf-ribbon_3 PF13248.6 OAG16259.1 - 0.087 12.3 2.1 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PPR_long PF17177.4 OAG16259.1 - 0.13 11.6 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP ATP_sub_h PF10775.9 OAG16260.1 - 8.9e-28 96.1 0.3 1.2e-27 95.7 0.3 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF1765 PF08578.10 OAG16261.1 - 4.9e-39 133.6 4.9 9.1e-39 132.8 4.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) K1 PF02960.14 OAG16262.1 - 0.086 13.0 0.4 0.11 12.6 0.3 1.3 1 1 0 1 1 1 0 K1 glycoprotein FtsX PF02687.21 OAG16262.1 - 0.33 11.5 4.9 0.53 10.8 4.9 1.2 1 0 0 1 1 1 0 FtsX-like permease family GNVR PF13807.6 OAG16262.1 - 3.6 7.6 6.7 1.4 8.9 4.2 1.9 2 1 0 2 2 2 0 G-rich domain on putative tyrosine kinase Fungal_trans_2 PF11951.8 OAG16263.1 - 2.7e-09 36.3 0.3 7.2e-09 34.9 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16263.1 - 1.6e-08 34.5 11.4 2.6e-08 33.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.6 OAG16264.1 - 3.1e-22 78.6 0.0 5.7e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG16264.1 - 1.2e-18 66.9 0.0 3.9e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG16264.1 - 0.061 13.6 0.1 2 8.7 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 OAG16265.1 - 5.3e-49 167.0 0.0 1.4e-48 165.6 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Stork_head PF10264.9 OAG16266.1 - 0.084 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain PGK PF00162.19 OAG16266.1 - 0.19 10.6 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase CUE PF02845.16 OAG16267.1 - 9.5e-11 41.2 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 OAG16267.1 - 0.019 15.0 0.3 0.019 15.0 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-associated protein 2 Metal_resist PF13801.6 OAG16267.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.0 2 1 1 3 3 3 0 Heavy-metal resistance PalH PF08733.10 OAG16270.1 - 0.21 10.6 3.2 7.6 5.4 0.3 2.4 2 0 0 2 2 2 0 PalH/RIM21 Oxidored_q2 PF00420.24 OAG16270.1 - 1.3 8.7 4.8 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HlyIII PF03006.20 OAG16271.1 - 1.4e-51 175.4 17.1 1.7e-51 175.1 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Epimerase PF01370.21 OAG16272.1 - 3.1e-07 30.1 0.0 1.2e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG16272.1 - 0.00065 19.6 0.0 0.017 15.1 0.0 2.6 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG16272.1 - 0.0018 17.5 0.0 0.01 15.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAG16272.1 - 0.033 13.2 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG16272.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF4427 PF14468.6 OAG16272.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) DUF3040 PF11239.8 OAG16273.1 - 0.039 14.2 0.6 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4257 PF14074.6 OAG16273.1 - 0.04 14.1 0.2 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) SLC3A2_N PF16028.5 OAG16273.1 - 0.097 12.2 5.2 3.5 7.2 0.9 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus COX7a PF02238.15 OAG16273.1 - 0.2 12.1 0.1 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Podoplanin PF05808.11 OAG16273.1 - 0.79 9.8 3.2 1.4 9.0 3.2 1.4 1 0 0 1 1 1 0 Podoplanin F-box-like PF12937.7 OAG16274.1 - 1.8e-08 34.1 0.1 4.9e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16274.1 - 0.00068 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain Paf1 PF03985.13 OAG16275.1 - 4.5e-63 213.7 0.0 8.1e-63 212.9 0.0 1.4 1 1 0 1 1 1 1 Paf1 FA_hydroxylase PF04116.13 OAG16276.1 - 1.6e-26 93.2 17.8 1.6e-26 93.2 17.8 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily SNF2_N PF00176.23 OAG16279.1 - 9.9e-64 215.2 0.0 1.9e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG16279.1 - 2.4e-18 66.5 0.0 5.7e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG16279.1 - 4.7e-07 30.0 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG16279.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Prefoldin_2 PF01920.20 OAG16279.1 - 0.17 11.9 2.7 3.2 7.8 0.0 2.7 1 1 1 2 2 2 0 Prefoldin subunit DUF2730 PF10805.8 OAG16279.1 - 0.21 11.7 0.5 0.59 10.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DNA_pol3_tau_4 PF12168.8 OAG16279.1 - 1.9 9.1 10.1 0.33 11.5 4.4 2.8 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding F-box PF00646.33 OAG16281.1 - 0.0058 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG16281.1 - 0.0093 15.8 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like Pox_Ag35 PF03286.14 OAG16284.1 - 0.15 11.8 2.7 0.17 11.7 2.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mg296 PF09644.10 OAG16286.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Mg296 protein Cellulase PF00150.18 OAG16287.1 - 1.2e-49 169.3 0.0 1.5e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 OAG16287.1 - 9.1e-12 44.7 8.6 9.1e-12 44.7 8.6 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Adeno_PV PF03910.13 OAG16287.1 - 5.1 5.7 8.1 8.5 5.0 8.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DAO PF01266.24 OAG16288.1 - 7.7e-42 144.1 0.0 8.9e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG16288.1 - 4e-05 23.8 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG16288.1 - 0.00074 18.8 0.0 0.018 14.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG16288.1 - 0.0011 19.0 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 OAG16288.1 - 0.0018 17.5 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 OAG16288.1 - 0.031 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 OAG16288.1 - 0.031 13.5 0.0 0.067 12.4 0.0 1.4 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.19 OAG16288.1 - 0.052 12.9 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.6 OAG16288.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_23 PF13489.6 OAG16289.1 - 4.6e-29 101.4 0.0 7.2e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16289.1 - 1.8e-07 31.8 0.0 4.3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG16289.1 - 3.3e-06 27.7 0.0 5.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG16289.1 - 4.2e-06 27.4 0.0 7.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG16289.1 - 4.8e-06 26.5 0.0 7.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pannexin_like PF12534.8 OAG16290.1 - 0.94 8.5 5.2 1.4 7.9 5.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF2235 PF09994.9 OAG16291.1 - 1.2e-80 271.0 0.0 1.7e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Acyl_transf_3 PF01757.22 OAG16292.1 - 1.1e-05 24.7 5.4 2e-05 23.8 5.2 1.5 1 1 0 1 1 1 1 Acyltransferase family NOA36 PF06524.12 OAG16293.1 - 0.24 10.7 9.2 0.38 10.0 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.9 OAG16293.1 - 1.8 7.0 4.8 2.1 6.8 4.8 1.1 1 0 0 1 1 1 0 Macoilin family RNA_pol_3_Rpc31 PF11705.8 OAG16294.1 - 1.1e-53 182.8 7.2 1.5e-53 182.3 7.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 OAG16294.1 - 0.0045 16.5 20.1 0.0055 16.2 20.1 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OAG16294.1 - 0.36 10.1 14.9 0.41 9.9 14.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 OAG16294.1 - 1.3 7.9 8.6 1.6 7.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 OAG16294.1 - 2.3 8.4 5.6 3.8 7.7 5.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AIF-MLS PF14962.6 OAG16294.1 - 2.4 8.1 8.8 3.5 7.6 8.8 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2457 PF10446.9 OAG16294.1 - 3.3 6.7 22.1 4.8 6.2 22.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CorA PF01544.18 OAG16296.1 - 0.0027 17.1 7.8 0.026 13.8 7.8 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PNK3P PF08645.11 OAG16296.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase LPD39 PF18858.1 OAG16296.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Pkinase PF00069.25 OAG16297.1 - 5.1e-21 75.2 0.0 1.1e-20 74.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 OAG16297.1 - 0.14 11.7 0.0 0.95 9.0 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase AAA PF00004.29 OAG16298.1 - 2.8e-19 69.8 0.0 5.6e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG16298.1 - 0.00012 22.5 0.1 0.0011 19.4 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain Zot PF05707.12 OAG16298.1 - 0.00014 21.6 0.2 0.0029 17.3 0.0 2.5 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 OAG16298.1 - 0.00047 20.4 0.1 0.0046 17.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_lid_6 PF17866.1 OAG16298.1 - 0.011 15.9 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA lid domain AAA_11 PF13086.6 OAG16298.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 OAG16298.1 - 0.035 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 OAG16298.1 - 0.041 14.2 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG16298.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAG16298.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAG16298.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OAG16298.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain CCD PF07860.11 OAG16298.1 - 0.094 12.8 0.8 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 WisP family C-Terminal Region AAA_33 PF13671.6 OAG16298.1 - 0.16 12.2 0.0 0.55 10.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF5617 PF18493.1 OAG16298.1 - 0.8 9.8 3.2 0.98 9.6 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5617) Pectate_lyase PF03211.13 OAG16299.1 - 1.2e-64 217.6 1.3 1.6e-64 217.2 1.3 1.1 1 0 0 1 1 1 1 Pectate lyase Epimerase PF01370.21 OAG16300.1 - 1.6e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG16300.1 - 1.7e-07 30.7 0.0 0.00033 19.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG16300.1 - 6.3e-07 29.1 0.1 1.1e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG16300.1 - 1.5e-06 27.4 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG16300.1 - 0.00072 19.5 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG16300.1 - 0.005 16.4 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG16300.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PAN_4 PF14295.6 OAG16300.1 - 0.16 11.9 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 PAN domain Not1 PF04054.15 OAG16303.1 - 1.1e-126 422.8 0.3 3.3e-126 421.1 0.3 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAG16303.1 - 2.4e-93 311.7 0.1 5.9e-93 310.4 0.1 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAG16303.1 - 2.4e-47 160.6 5.6 7e-47 159.0 5.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAG16303.1 - 1.3e-45 155.0 0.0 3.2e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAG16303.1 - 4e-31 108.1 0.5 1.4e-30 106.3 0.5 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat IQ_SEC7_PH PF16453.5 OAG16303.1 - 0.045 13.7 0.8 0.44 10.5 0.1 2.6 2 0 0 2 2 2 0 PH domain Prion PF00377.18 OAG16303.1 - 0.051 13.4 0.6 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain DUF1835 PF08874.10 OAG16303.1 - 0.41 10.9 1.8 1.7 8.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) MA3 PF02847.17 OAG16303.1 - 1.3 9.0 3.9 38 4.3 0.1 4.0 4 0 0 4 4 4 0 MA3 domain FCH PF00611.23 OAG16304.1 - 3.9e-13 49.5 0.1 1.5e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OAG16304.1 - 1.1e-12 47.3 0.0 2.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG16304.1 - 2.4e-12 46.5 0.1 4.1e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG16304.1 - 1.9e-10 40.2 0.0 7.9e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Rapsyn_N PF10579.9 OAG16304.1 - 0.14 12.2 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region SoPB_HTH PF18090.1 OAG16305.1 - 0.15 12.2 0.0 0.76 10.0 0.0 2.0 2 0 0 2 2 2 0 Centromere-binding protein HTH domain MPM1 PF17234.2 OAG16307.1 - 0.068 13.4 0.6 0.09 13.0 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF2810 PF10928.8 OAG16307.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) DUF853 PF05872.12 OAG16308.1 - 0.61 8.6 3.8 0.71 8.4 3.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FTO_CTD PF12934.7 OAG16309.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain YrhK PF14145.6 OAG16310.1 - 0.43 10.5 25.4 5.4 7.0 3.2 4.8 3 2 0 3 3 3 0 YrhK-like protein MFS_1 PF07690.16 OAG16311.1 - 2.5e-43 148.4 40.8 8e-43 146.7 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG16311.1 - 6.9e-14 51.6 18.6 1.2e-13 50.7 18.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG16311.1 - 4.4e-09 35.3 0.7 6.4e-09 34.8 0.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG16311.1 - 2.9e-07 30.1 3.2 2.9e-07 30.1 3.2 1.8 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG16311.1 - 0.34 9.1 13.1 0.022 13.1 1.9 3.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BTB PF00651.31 OAG16312.1 - 0.00075 19.7 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 OAG16313.1 - 1.1e-53 182.3 0.0 1.6e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16313.1 - 4.3e-33 114.7 0.0 5.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG16313.1 - 0.00014 21.2 0.0 0.00034 20.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OAG16313.1 - 0.00017 21.6 0.1 0.0006 19.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG16313.1 - 0.0036 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG16313.1 - 0.28 10.1 1.7 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain DUF456 PF04306.13 OAG16315.1 - 0.0075 16.6 4.0 0.012 15.9 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF572 PF04502.13 OAG16316.1 - 2.1e-08 34.2 4.8 6.3e-08 32.6 0.4 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF572) Oxidored-like PF09791.9 OAG16318.1 - 1.8e-25 88.3 4.5 1.8e-25 88.3 4.5 2.2 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.11 OAG16319.1 - 1.1e-38 131.3 0.2 1.2e-38 131.1 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 OAG16319.1 - 0.025 14.6 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2523 PF10734.9 OAG16319.1 - 0.055 14.0 0.6 0.079 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) TrkA_N PF02254.18 OAG16320.1 - 0.043 14.1 0.4 10 6.4 0.0 3.5 2 1 1 3 3 3 0 TrkA-N domain Adaptin_N PF01602.20 OAG16322.1 - 1.9e-120 402.9 8.7 2.3e-120 402.6 8.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAG16322.1 - 4.2e-47 159.0 0.0 1.3e-46 157.5 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAG16322.1 - 1.1e-18 67.5 0.0 2.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG16322.1 - 1.1e-05 25.6 2.2 0.014 15.4 0.0 2.8 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG16322.1 - 0.02 15.3 1.4 2.2 8.7 0.1 4.0 4 0 0 4 4 4 0 HEAT repeats AP4E_app_platf PF14807.6 OAG16322.1 - 0.11 12.8 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF1768 PF08719.11 OAG16323.1 - 1.4e-54 184.7 1.6 1.6e-54 184.5 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Fungal_trans PF04082.18 OAG16325.1 - 2.6e-16 59.5 0.1 4e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliS PF02561.14 OAG16325.1 - 0.046 14.0 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliS HET PF06985.11 OAG16326.1 - 4e-27 95.4 0.6 6.7e-27 94.6 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ala_racemase_N PF01168.20 OAG16327.1 - 1.8e-24 86.6 0.0 2.2e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fer4_24 PF18109.1 OAG16327.1 - 0.0041 17.4 1.2 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 Ferredoxin I 4Fe-4S cluster domain Abhydrolase_6 PF12697.7 OAG16328.1 - 0.00026 21.7 2.5 0.00065 20.4 2.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldose_epim PF01263.20 OAG16329.1 - 2e-44 152.1 0.7 2.5e-44 151.8 0.7 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GDPD PF03009.17 OAG16331.1 - 0.05 13.3 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 OAG16331.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain MS_channel PF00924.18 OAG16332.1 - 7.8e-16 58.2 1.6 1.8e-15 57.0 1.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAG16332.1 - 0.0009 18.6 0.1 0.0021 17.5 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OAG16332.1 - 0.0033 16.8 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OAG16332.1 - 0.0075 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OAG16332.1 - 0.01 15.7 0.0 0.04 13.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain MARVEL PF01284.23 OAG16333.1 - 0.0002 21.4 5.0 0.00023 21.2 5.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain Collectrin PF16959.5 OAG16334.1 - 0.13 12.0 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Renal amino acid transporter PIG-Y PF15159.6 OAG16335.1 - 2e-22 79.9 7.8 3.1e-22 79.3 7.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 OAG16335.1 - 0.013 16.0 3.2 1.4 9.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Cation_efflux PF01545.21 OAG16336.1 - 5.2e-09 36.1 11.0 6.8e-09 35.7 11.0 1.1 1 0 0 1 1 1 1 Cation efflux family IBR PF01485.21 OAG16337.1 - 9.1e-08 32.2 10.0 9.1e-08 32.2 10.0 3.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OAG16337.1 - 0.017 15.0 1.8 0.017 15.0 1.8 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) V-ATPase_G PF03179.15 OAG16337.1 - 5 7.7 12.0 13 6.4 12.0 1.7 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit zf-RING_2 PF13639.6 OAG16337.1 - 5.2 7.5 27.8 0.069 13.5 5.4 3.6 3 0 0 3 3 3 0 Ring finger domain TFIIB PF00382.19 OAG16338.1 - 0.11 12.5 0.3 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Terminase_4 PF05119.12 OAG16340.1 - 0.16 12.4 0.3 2.2 8.8 0.2 2.1 1 1 1 2 2 2 0 Phage terminase, small subunit Epimerase PF01370.21 OAG16341.1 - 3.8e-11 42.9 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG16341.1 - 1.7e-07 30.6 0.0 2.6e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG16341.1 - 6.9e-06 25.4 0.0 2.2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG16341.1 - 0.03 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Tautomerase_3 PF14832.6 OAG16342.1 - 3.2e-36 124.6 0.3 3.7e-36 124.4 0.3 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WXG100 PF06013.12 OAG16343.1 - 0.058 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG CDC27 PF09507.10 OAG16343.1 - 0.35 10.2 19.7 0.41 10.0 19.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ORC6 PF05460.13 OAG16343.1 - 5.1 6.3 17.5 6 6.0 17.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ish1 PF10281.9 OAG16344.1 - 2.5e-48 162.1 15.4 2e-14 53.6 0.0 5.1 5 0 0 5 5 5 4 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 OAG16344.1 - 0.003 17.5 0.9 5.2 7.1 0.0 4.1 4 0 0 4 4 4 1 Slx4 endonuclease HeH PF12949.7 OAG16344.1 - 0.0034 17.1 0.0 2.1 8.1 0.0 3.5 4 0 0 4 4 4 2 HeH/LEM domain SAP PF02037.27 OAG16344.1 - 0.0092 15.7 0.0 2.3 8.0 0.0 3.5 3 1 0 3 3 3 1 SAP domain Dickkopf_N PF04706.12 OAG16349.1 - 1.2 9.6 17.9 0.26 11.8 13.4 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF1797 PF08796.10 OAG16356.1 - 0.062 13.4 0.3 0.13 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) p450 PF00067.22 OAG16359.1 - 2.4e-55 188.1 0.0 3.5e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glycos_transf_1 PF00534.20 OAG16360.1 - 1.4e-09 37.8 0.0 2.8e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG16360.1 - 6.4e-09 36.3 0.0 1.3e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG16360.1 - 0.045 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ADH_N PF08240.12 OAG16361.1 - 1.7e-29 101.9 3.1 3.1e-29 101.0 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG16361.1 - 1.9e-10 40.8 0.0 7.7e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG16361.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3433 PF11915.8 OAG16362.1 - 4e-42 142.6 16.5 3.9e-23 81.7 1.6 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF3433) DUF2569 PF10754.9 OAG16362.1 - 0.046 14.1 1.5 0.27 11.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF3708 PF12501.8 OAG16362.1 - 0.085 12.6 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter CcmD PF04995.14 OAG16362.1 - 9.2 6.4 8.4 1.1 9.4 1.0 3.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Arf PF00025.21 OAG16363.1 - 9.4e-75 249.9 0.1 1e-74 249.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG16363.1 - 1.3e-14 54.4 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG16363.1 - 1.2e-12 47.6 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG16363.1 - 3e-11 43.1 0.3 4.2e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG16363.1 - 8.1e-11 41.8 0.0 9.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG16363.1 - 6.9e-09 35.4 0.0 8.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG16363.1 - 6.5e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG16363.1 - 0.00032 20.3 0.0 0.028 14.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG16363.1 - 0.004 16.7 0.6 0.018 14.5 0.6 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 OAG16363.1 - 0.094 13.3 0.2 0.26 11.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain Ric8 PF10165.9 OAG16364.1 - 0.00049 19.3 0.9 0.00053 19.1 0.9 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF676 PF05057.14 OAG16366.1 - 0.00043 19.9 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAG16366.1 - 0.0026 17.0 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 OAG16366.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OAG16366.1 - 0.014 16.0 1.8 0.039 14.6 2.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OAG16366.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF726 PF05277.12 OAG16366.1 - 0.042 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 OAG16366.1 - 0.069 12.9 0.1 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 OAG16366.1 - 0.083 12.5 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.8 OAG16366.1 - 0.086 12.4 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.16 OAG16366.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AAA_16 PF13191.6 OAG16367.1 - 7.1e-07 29.8 0.1 1.2e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAG16367.1 - 5.8e-06 26.3 1.0 1.1e-05 25.4 1.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG16367.1 - 1.6e-05 25.2 0.1 3.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OAG16367.1 - 4.3e-05 22.8 0.1 5.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 OAG16367.1 - 0.00011 22.6 0.5 0.0016 18.9 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 OAG16367.1 - 0.14 11.4 0.7 0.22 10.7 0.5 1.6 1 1 1 2 2 2 0 KAP family P-loop domain Ank_2 PF12796.7 OAG16368.1 - 6.1e-19 68.4 0.0 5.9e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG16368.1 - 8.6e-16 56.5 0.0 0.0052 17.2 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OAG16368.1 - 9.3e-15 54.3 0.2 0.00057 20.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG16368.1 - 1.8e-14 53.6 0.1 8e-05 22.9 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG16368.1 - 1e-08 35.5 0.0 6.5e-06 26.6 0.0 3.6 2 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3176 PF11374.8 OAG16369.1 - 2e-28 98.7 2.8 4.5e-28 97.6 2.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4131 PF13567.6 OAG16369.1 - 4.6 6.9 6.2 1.7 8.3 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) FAD_binding_4 PF01565.23 OAG16370.1 - 4.2e-20 71.9 1.0 7.9e-20 71.0 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG16370.1 - 4.7e-09 36.2 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.24 OAG16371.1 - 6.5e-127 424.1 22.8 7.5e-127 423.9 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16371.1 - 1e-21 77.3 37.3 1.7e-20 73.3 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5357 PF17310.2 OAG16371.1 - 9.1 4.7 6.2 5.4 5.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5357) FMN_dh PF01070.18 OAG16372.1 - 1.3e-115 386.2 0.1 1.8e-115 385.7 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 OAG16372.1 - 2.6e-05 23.7 0.0 0.092 12.0 0.0 2.6 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG16372.1 - 2.8e-05 23.3 0.6 4.7e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG16372.1 - 0.0044 16.2 0.2 0.0064 15.7 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG16372.1 - 0.014 14.8 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 OAG16372.1 - 0.027 13.9 0.9 3.1 7.2 0.0 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein IGPS PF00218.21 OAG16372.1 - 0.077 12.2 0.3 0.74 8.9 0.3 2.2 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Methyltransf_2 PF00891.18 OAG16373.1 - 1.7e-26 92.8 0.0 2.5e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MFS_1 PF07690.16 OAG16374.1 - 5e-33 114.5 51.2 5.9e-33 114.3 51.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG16374.1 - 2.5e-05 23.3 27.8 0.0078 15.1 15.0 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter AA_permease PF00324.21 OAG16375.1 - 3.7e-83 279.7 25.8 4.6e-83 279.4 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG16375.1 - 9.7e-18 64.2 31.7 1.2e-17 63.9 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_1 PF04531.13 OAG16375.1 - 0.044 14.3 0.0 0.18 12.3 0.0 2.1 1 0 0 1 1 1 0 Bacteriophage holin HET PF06985.11 OAG16376.1 - 1.9e-12 47.8 1.8 2.7e-09 37.5 0.5 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Hva1_TUDOR PF11160.8 OAG16377.1 - 1.4e-16 60.4 2.7 1.4e-16 60.4 2.7 3.3 4 2 1 5 5 5 1 Hypervirulence associated proteins TUDOR domain HlyIII PF03006.20 OAG16378.1 - 1.5e-64 217.8 9.7 1.7e-64 217.6 9.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 OAG16378.1 - 0.035 14.2 1.9 0.18 11.9 1.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF962) HisKA_7TM PF16927.5 OAG16378.1 - 0.066 13.3 12.0 0.13 12.3 12.0 1.6 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF373 PF04123.13 OAG16378.1 - 1.7 8.0 3.7 1.8 7.9 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4231 PF14015.6 OAG16378.1 - 1.7 9.1 5.0 40 4.7 0.3 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF4231) CSN8_PSD8_EIF3K PF10075.9 OAG16379.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Brix PF04427.18 OAG16380.1 - 5.9e-48 163.5 0.1 8.6e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain MscS_TM PF12794.7 OAG16380.1 - 0.33 9.8 4.3 0.61 8.9 4.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DEAD PF00270.29 OAG16381.1 - 6.6e-48 162.8 0.0 9.8e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG16381.1 - 1.1e-30 106.2 0.0 5.2e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG16381.1 - 0.0034 17.4 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG16381.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FoP_duplication PF13865.6 OAG16381.1 - 1.8 9.1 11.6 5 7.7 11.6 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Haem_degrading PF03928.14 OAG16382.1 - 4.8e-29 100.8 0.0 7.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading YAcAr PF10686.9 OAG16382.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Peptidase_S8 PF00082.22 OAG16383.1 - 5.7e-25 88.2 0.7 8.9e-25 87.6 0.7 1.3 1 0 0 1 1 1 1 Subtilase family MRP-L27 PF09809.9 OAG16383.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 Lipase_GDSL_2 PF13472.6 OAG16384.1 - 6.8e-10 39.6 0.3 8.8e-10 39.3 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG16384.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ferritin_2 PF13668.6 OAG16385.1 - 3e-15 56.6 0.0 4.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain TRM PF02005.16 OAG16386.1 - 4.7e-116 388.0 0.0 1.6e-100 336.9 0.0 2.0 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OAG16386.1 - 0.0042 16.9 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein Nop25 PF09805.9 OAG16386.1 - 0.039 14.4 8.0 0.082 13.4 8.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) MTS PF05175.14 OAG16386.1 - 0.046 13.3 0.1 0.097 12.2 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Auto_anti-p27 PF06677.12 OAG16386.1 - 0.86 9.8 3.2 0.89 9.8 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2951 PF11166.8 OAG16386.1 - 1.2 9.4 6.8 2.9 8.2 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) LRRCT PF01463.24 OAG16387.1 - 0.14 12.7 1.0 0.52 11.0 0.1 2.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain HRI1 PF16815.5 OAG16388.1 - 1.4e-70 237.6 1.8 1.9e-70 237.2 1.8 1.1 1 0 0 1 1 1 1 Protein HRI1 Ribosomal_L13e PF01294.18 OAG16389.1 - 2.7e-76 255.4 5.0 3.9e-76 254.9 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e LRR_8 PF13855.6 OAG16390.1 - 9e-34 115.0 30.9 1.2e-08 34.6 2.7 7.1 6 0 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OAG16390.1 - 2.3e-26 91.4 48.9 9.4e-07 29.1 0.6 9.9 4 3 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAG16390.1 - 3.6e-07 29.9 22.9 0.11 11.9 0.9 5.4 2 2 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 OAG16390.1 - 0.0055 17.1 27.9 23 6.1 0.3 10.1 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 OAG16390.1 - 0.078 13.1 27.3 33 4.9 0.0 10.6 11 1 0 11 11 11 0 Leucine Rich repeat T3SS_needle_E PF08988.10 OAG16390.1 - 0.55 10.4 2.8 1.4 9.2 0.1 2.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF1844 PF08899.11 OAG16391.1 - 0.043 14.1 0.3 0.16 12.3 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) PDCD7 PF16021.5 OAG16391.1 - 0.11 11.6 11.2 0.19 10.8 11.2 1.4 1 0 0 1 1 1 0 Programmed cell death protein 7 Exonuc_VII_L PF02601.15 OAG16391.1 - 4.4 6.8 9.7 7.4 6.0 9.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ArAE_2_N PF10337.9 OAG16391.1 - 7.3 5.5 6.2 12 4.8 6.2 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal GFO_IDH_MocA PF01408.22 OAG16392.1 - 8.8e-17 62.0 0.0 1.6e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG16392.1 - 0.00081 20.0 0.1 0.0016 19.1 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NMO PF03060.15 OAG16393.1 - 1.7e-32 113.2 2.4 3e-24 86.0 1.2 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 OAG16393.1 - 7.5e-11 41.6 0.0 0.00011 21.4 1.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG16393.1 - 2.3e-06 26.9 3.9 3.6e-06 26.3 3.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG16393.1 - 5.6e-06 25.7 0.1 8.4e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Tautomerase_3 PF14832.6 OAG16394.1 - 7.8e-42 142.7 0.1 8.9e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DUF4551 PF15087.6 OAG16395.1 - 0.29 9.9 3.1 0.37 9.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Prismane PF03063.20 OAG16396.1 - 0.025 13.3 0.2 0.031 13.0 0.2 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family zf-C2H2_jaz PF12171.8 OAG16397.1 - 6.8e-06 26.2 0.5 1.1e-05 25.6 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG16397.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OAG16397.1 - 0.0029 18.0 0.5 0.0029 18.0 0.5 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG16397.1 - 0.14 13.1 0.1 0.14 13.1 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1691 PF07950.11 OAG16398.1 - 2.9e-37 127.7 4.0 3.5e-32 111.3 2.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Alpha-amylase PF00128.24 OAG16399.1 - 6.7e-105 351.4 0.6 1.3e-104 350.4 0.2 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG16399.1 - 3.1e-06 27.2 0.0 0.00026 21.0 0.0 2.6 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAG16399.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 OAG16399.1 - 0.091 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Sugar_tr PF00083.24 OAG16400.1 - 1.6e-85 287.7 24.3 2.7e-85 286.9 24.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16400.1 - 5.9e-21 74.8 37.6 7.4e-20 71.2 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG16400.1 - 1.2e-09 38.1 8.2 1.9e-09 37.5 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_2 PF13347.6 OAG16400.1 - 0.0068 15.0 21.5 0.088 11.3 10.0 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein ACI44 PF15270.6 OAG16403.1 - 0.16 12.2 0.3 0.35 11.1 0.3 1.5 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor MLTR_LBD PF17765.1 OAG16403.1 - 0.16 12.1 0.1 24 5.0 0.0 2.3 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain DUF1816 PF08846.10 OAG16404.1 - 0.16 12.0 0.1 24 5.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) APC_u14 PF16635.5 OAG16404.1 - 0.2 12.2 2.6 0.31 11.6 0.5 2.5 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Transket_pyr PF02779.24 OAG16405.1 - 4.8e-49 166.4 0.0 7.1e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG16405.1 - 4.8e-34 116.9 0.0 1.2e-33 115.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.10 OAG16406.1 - 8.1e-30 102.9 0.2 1.4e-29 102.2 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAG16406.1 - 2.7e-20 72.8 0.0 5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16406.1 - 8.4e-19 68.1 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG16406.1 - 3.9e-17 62.5 0.0 5.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG16406.1 - 6.7e-14 51.8 0.1 9.6e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG16406.1 - 8.6e-12 45.2 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG16406.1 - 2.4e-09 36.9 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG16406.1 - 6.1e-09 36.5 0.0 1.4e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OAG16406.1 - 4.3e-05 22.3 0.0 6.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 OAG16406.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 OAG16406.1 - 0.00024 20.3 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 OAG16406.1 - 0.0013 18.1 0.1 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OAG16406.1 - 0.0034 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAG16406.1 - 0.0043 17.1 0.4 0.0082 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAG16406.1 - 0.0044 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAG16406.1 - 0.0055 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 OAG16406.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 OAG16406.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 OAG16406.1 - 0.084 13.9 0.0 0.36 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain VAPB_antitox PF02697.14 OAG16406.1 - 0.16 12.8 0.3 0.42 11.4 0.3 1.6 1 0 0 1 1 1 0 Putative antitoxin RRM_1 PF00076.22 OAG16407.1 - 2.8e-08 33.5 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG16407.1 - 0.0029 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG16407.1 - 0.023 14.8 0.1 0.067 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Complex1_LYR PF05347.15 OAG16408.1 - 1.8e-05 24.7 0.3 4.1e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG16408.1 - 0.065 14.0 0.8 0.087 13.6 0.8 1.4 1 1 0 1 1 1 0 Complex1_LYR-like zinc_ribbon_10 PF10058.9 OAG16409.1 - 1.8e-19 69.2 0.1 3.8e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Cep57_CLD_2 PF14197.6 OAG16409.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MAS20 PF02064.15 OAG16409.1 - 0.031 14.4 0.4 0.074 13.2 0.4 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor RNase_H2-Ydr279 PF09468.10 OAG16410.1 - 2.4e-42 144.9 1.8 2.7e-42 144.7 0.2 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAG16410.1 - 7.7e-26 90.2 0.0 2.3e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain zf-primase PF09329.11 OAG16411.1 - 1.5e-17 63.2 1.8 2.5e-17 62.4 1.8 1.4 1 0 0 1 1 1 1 Primase zinc finger TTL PF03133.15 OAG16412.1 - 2e-51 174.9 0.0 4.5e-51 173.7 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family SDA1 PF05285.12 OAG16412.1 - 0.037 13.5 7.2 0.05 13.0 7.2 1.1 1 0 0 1 1 1 0 SDA1 DASH_Duo1 PF08651.10 OAG16414.1 - 1.4e-31 108.0 3.3 2e-31 107.6 3.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 OAG16414.1 - 0.4 11.1 11.7 0.041 14.3 7.4 1.7 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF5568 PF17724.1 OAG16414.1 - 0.94 9.3 9.2 0.084 12.7 4.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5568) 3HCDH_N PF02737.18 OAG16414.1 - 3.5 7.5 10.5 0.18 11.7 1.8 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF745 PF05335.13 OAG16414.1 - 4.9 6.8 18.6 14 5.4 18.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Macoilin PF09726.9 OAG16414.1 - 6.6 5.2 11.2 8.8 4.7 11.2 1.1 1 0 0 1 1 1 0 Macoilin family GalKase_gal_bdg PF10509.9 OAG16415.1 - 7e-21 73.5 0.0 1.3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAG16415.1 - 3.4e-15 56.0 2.8 8e-15 54.8 2.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG16415.1 - 6.1e-14 52.2 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Fungal_trans PF04082.18 OAG16418.1 - 5.4e-06 25.6 0.1 1.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Goodbye PF17109.5 OAG16419.1 - 4.2e-18 65.9 0.5 2.5e-17 63.4 0.1 2.7 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain TPR_7 PF13176.6 OAG16419.1 - 0.015 15.3 0.3 17 5.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Init_tRNA_PT PF04179.12 OAG16419.1 - 0.015 15.6 0.0 0.059 13.7 0.0 2.0 1 0 0 1 1 1 0 Rit1 DUSP-like domain TPR_1 PF00515.28 OAG16419.1 - 0.21 11.5 6.9 30 4.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG16419.1 - 0.57 10.4 7.7 67 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG16419.1 - 3.8 8.0 8.3 23 5.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CorA PF01544.18 OAG16421.1 - 1e-08 34.9 0.2 1.7e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 OAG16422.1 - 0.0014 17.6 7.9 0.0014 17.6 7.9 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 OAG16422.1 - 0.022 13.4 8.0 0.029 12.9 8.0 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein HTH_Tnp_Tc5 PF03221.16 OAG16423.1 - 3.2e-10 39.9 0.0 6.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG16423.1 - 0.0015 18.3 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_6 PF01418.17 OAG16423.1 - 0.0022 17.9 0.0 0.069 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 OAG16423.1 - 0.062 13.1 0.2 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain GntR PF00392.21 OAG16423.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_49 PF18010.1 OAG16423.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain Rhodanese PF00581.20 OAG16424.1 - 1.3e-13 51.4 0.0 2.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 OAG16425.1 - 3.6e-14 52.7 0.0 2.4e-12 46.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG16425.1 - 2.4e-13 49.4 0.0 3.5e-12 45.5 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG16425.1 - 4.6e-11 42.5 0.0 1.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG16425.1 - 5.6e-11 42.2 0.0 2.6e-08 33.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG16425.1 - 4.6e-06 26.8 0.9 1.7e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG16425.1 - 0.00014 21.9 0.4 0.46 10.5 0.1 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG16425.1 - 0.00024 21.2 0.0 2.8 8.0 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG16425.1 - 0.00037 21.0 1.2 1.1 9.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG16425.1 - 0.014 14.7 0.2 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAG16425.1 - 0.066 12.3 0.9 0.12 11.5 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 OAG16425.1 - 0.097 11.9 0.0 4.3 6.5 0.0 2.2 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 OAG16425.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG16425.1 - 0.17 11.1 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG16425.1 - 0.97 8.9 6.9 0.16 11.6 1.7 2.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 OAG16425.1 - 3.3 6.7 5.2 0.45 9.6 0.4 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A PCI PF01399.27 OAG16426.1 - 0.0072 16.8 0.0 0.085 13.4 0.0 2.5 2 0 0 2 2 2 1 PCI domain AhpC-TSA PF00578.21 OAG16427.1 - 1.5e-29 102.4 0.0 2.9e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 OAG16427.1 - 7.3e-14 51.3 0.1 1.5e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 OAG16427.1 - 2e-13 50.3 0.0 4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Redoxin SSXT PF05030.12 OAG16428.1 - 2.6e-06 27.0 0.1 2.6e-06 27.0 0.1 3.3 3 1 0 3 3 3 1 SSXT protein (N-terminal region) MPM1 PF17234.2 OAG16428.1 - 4.6 7.5 12.3 0.16 12.2 2.8 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PGA2 PF07543.12 OAG16428.1 - 6.9 6.6 11.1 12 5.9 4.1 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 FtsJ PF01728.19 OAG16429.1 - 6.3e-52 176.2 0.0 8.8e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OAG16429.1 - 0.01 15.6 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16429.1 - 0.023 15.4 0.0 0.54 11.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 OAG16430.1 - 5.9e-73 240.9 1.9 3.6e-24 84.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG16430.1 - 0.00057 19.1 0.3 0.19 10.8 0.1 3.1 4 1 0 4 4 4 2 Gammaproteobacterial serine protease GAD-like PF08887.11 OAG16430.1 - 0.0023 17.7 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 GAD-like domain 2Fe-2S_thioredx PF01257.19 OAG16431.1 - 7.4e-61 204.2 0.5 9.4e-61 203.9 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3824 PF12868.7 OAG16434.1 - 1.1e-37 130.0 32.9 1.1e-37 130.0 32.9 10.5 5 4 4 11 11 11 3 Domain of unknwon function (DUF3824) DUF533 PF04391.12 OAG16434.1 - 0.27 10.8 16.9 1.8 8.1 0.5 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF533) ABA_WDS PF02496.16 OAG16434.1 - 0.29 11.6 27.1 1.1 9.8 1.4 5.4 4 1 0 4 4 4 0 ABA/WDS induced protein CorA PF01544.18 OAG16435.1 - 1.5e-25 90.1 1.1 7.6e-22 78.0 1.3 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 OAG16436.1 - 1.7e-28 99.6 35.2 1.7e-28 99.6 35.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.8 OAG16436.1 - 0.095 12.8 0.1 13 5.9 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function Chlorosome_CsmC PF11098.8 OAG16437.1 - 1.5 8.8 6.3 6.2 6.8 1.9 2.2 2 0 0 2 2 2 0 Chlorosome envelope protein C IHABP4_N PF16174.5 OAG16438.1 - 0.74 10.4 11.2 1.1 9.8 11.2 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SRP-alpha_N PF04086.13 OAG16438.1 - 1.3 8.9 7.1 1.5 8.7 7.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 OAG16438.1 - 6.3 5.4 6.1 6.5 5.4 6.1 1.1 1 0 0 1 1 1 0 Presenilin Acyltransferase PF01553.21 OAG16439.1 - 2.5e-27 95.1 0.0 4.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAG16439.1 - 7.4e-13 48.4 0.3 1.9e-12 47.1 0.3 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Hep_59 PF07052.11 OAG16440.1 - 1.8e-05 25.4 2.6 3.2e-05 24.6 0.0 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 SesA PF17107.5 OAG16440.1 - 0.066 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CBP_BcsS PF17036.5 OAG16440.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS NifU_N PF01592.16 OAG16441.1 - 1.3e-50 170.8 0.0 1.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 OAG16441.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain UCH PF00443.29 OAG16442.1 - 1.7e-23 83.4 0.0 2.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG16442.1 - 1.3e-20 73.5 0.9 1.3e-20 73.5 0.9 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OAG16442.1 - 5.2e-20 71.0 0.1 1.3e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 OAG16442.1 - 7.4e-09 35.6 5.4 2.3e-06 27.4 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 OAG16442.1 - 0.0093 15.8 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain DNA_pol_phi PF04931.13 OAG16443.1 - 1.5e-215 717.8 34.0 1.9e-215 717.5 34.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 OAG16443.1 - 2.5 7.4 41.6 0.012 15.1 26.8 3.0 3 0 0 3 3 3 0 SDA1 Med4 PF10018.9 OAG16444.1 - 5.7e-36 124.0 3.2 8e-36 123.5 3.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4972 PF16342.5 OAG16444.1 - 0.07 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) AAA_13 PF13166.6 OAG16444.1 - 0.1 11.2 1.1 0.14 10.8 1.1 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 OAG16444.1 - 0.21 11.8 0.7 0.38 10.9 0.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 OAG16444.1 - 1.2 9.5 3.8 0.63 10.4 0.5 2.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 EF-hand_7 PF13499.6 OAG16445.1 - 6.9e-24 84.1 7.7 1.9e-15 57.0 0.5 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAG16445.1 - 5.2e-23 79.0 5.1 4.3e-06 26.2 0.1 5.6 5 1 1 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 OAG16445.1 - 8.9e-23 78.1 16.5 4.8e-08 32.0 0.1 5.2 6 1 1 7 7 7 3 EF hand EF-hand_5 PF13202.6 OAG16445.1 - 1.7e-17 62.1 11.6 3.2e-05 23.2 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OAG16445.1 - 1.7e-13 50.2 11.2 2.9e-05 23.8 0.9 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 OAG16445.1 - 4.3e-08 33.0 7.1 0.0023 17.8 0.1 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAG16445.1 - 0.00064 20.0 3.4 1 9.7 0.2 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OAG16445.1 - 0.00075 19.8 0.4 0.022 15.1 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 OAG16445.1 - 0.3 11.0 2.9 2.5 8.0 0.0 3.4 3 1 0 3 3 3 0 EF hand EMP70 PF02990.16 OAG16446.1 - 3.2e-206 686.0 0.3 4e-206 685.7 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3920 PF13058.6 OAG16446.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) MFS_1 PF07690.16 OAG16447.1 - 8.9e-43 146.6 28.8 8.9e-43 146.6 28.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG16447.1 - 1.5e-13 50.1 2.1 2.3e-13 49.5 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG16447.1 - 1.9e-06 27.4 3.4 1.9e-06 27.4 3.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB HECW1_helix PF18436.1 OAG16447.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 PGG PF13962.6 OAG16447.1 - 2.4 8.0 8.1 0.73 9.7 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function Fungal_trans PF04082.18 OAG16448.1 - 8.9e-10 38.0 1.1 1.5e-09 37.3 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16448.1 - 6.4e-07 29.4 9.3 1.4e-06 28.3 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VID27 PF08553.10 OAG16449.1 - 2.8e-191 635.1 0.2 4.4e-191 634.5 0.2 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAG16449.1 - 3.5e-72 241.8 0.7 3.5e-72 241.8 0.7 2.3 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 OAG16449.1 - 6.5e-44 148.7 0.3 3.6e-43 146.3 0.2 2.2 2 0 0 2 2 2 1 VID27 PH-like domain CobT PF06213.12 OAG16449.1 - 3 7.1 12.6 5.6 6.3 12.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OAG16449.1 - 6.3 5.0 7.4 9.1 4.4 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SnoaL_2 PF12680.7 OAG16450.1 - 5.2e-05 23.8 0.0 9.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG16450.1 - 0.00052 19.8 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Ank_4 PF13637.6 OAG16451.1 - 2.3e-05 24.9 0.1 0.23 12.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG16451.1 - 0.001 19.6 0.1 0.042 14.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG16451.1 - 0.066 13.6 0.1 3.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 OAG16451.1 - 0.072 13.6 0.3 0.85 10.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat NMT1 PF09084.11 OAG16452.1 - 7e-11 42.5 0.0 1.6e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 OAG16452.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family PSCyt2 PF07583.11 OAG16452.1 - 0.02 14.8 0.2 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) SBP_bac_3 PF00497.20 OAG16452.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Hemerythrin PF01814.23 OAG16452.1 - 0.027 15.1 0.1 0.04 14.5 0.1 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DLH PF01738.18 OAG16453.1 - 9.1e-16 58.1 0.3 1.1e-13 51.2 0.3 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Rep_fac-A_C PF08646.10 OAG16454.1 - 5.6e-53 178.6 4.8 2.3e-50 170.1 2.4 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAG16454.1 - 4.2e-36 122.8 0.6 9.4e-36 121.7 0.6 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 OAG16454.1 - 3.8e-21 75.0 0.4 3.8e-21 75.0 0.4 2.3 3 0 0 3 3 3 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAG16454.1 - 1.7e-13 50.4 0.1 2.5e-08 33.8 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OAG16454.1 - 0.0024 17.6 0.2 0.59 9.8 0.0 2.9 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 OAG16454.1 - 0.016 13.7 0.1 0.026 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF4539 PF15072.6 OAG16454.1 - 0.036 14.1 0.1 0.41 10.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) ADH_zinc_N PF00107.26 OAG16455.1 - 2.7e-19 69.5 0.2 4.7e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG16455.1 - 1.4e-17 65.0 0.0 2.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG16455.1 - 1.1e-06 28.4 0.0 4.9e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG16455.1 - 0.0015 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Zeta_toxin PF06414.12 OAG16455.1 - 0.02 14.2 0.3 0.07 12.4 0.3 1.8 1 1 0 1 1 1 0 Zeta toxin F_bP_aldolase PF01116.20 OAG16455.1 - 0.069 12.6 0.1 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Glyco_hydro_cc PF11790.8 OAG16456.1 - 2.3e-56 191.1 0.4 3.2e-56 190.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sua5_yciO_yrdC PF01300.18 OAG16459.1 - 1.3e-51 174.6 0.0 2.6e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAG16459.1 - 3.4e-33 115.1 0.0 8.5e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pantoate_transf PF02548.15 OAG16459.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Cofilin_ADF PF00241.20 OAG16460.1 - 5.2e-23 81.1 0.2 6e-23 80.9 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.7 OAG16461.1 - 4.7e-06 26.4 0.1 9.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16461.1 - 0.00028 20.7 0.0 0.00068 19.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain EH_Signature PF15611.6 OAG16461.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 EH_Signature domain KH_5 PF13184.6 OAG16461.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NusA-like KH domain F-box_4 PF15966.5 OAG16461.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box SIR2 PF02146.17 OAG16462.1 - 9.3e-55 185.3 0.0 1.5e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family VitD-bind_III PF09164.10 OAG16462.1 - 0.09 12.8 0.7 0.47 10.5 0.7 2.2 1 1 1 2 2 2 0 Vitamin D binding protein, domain III baeRF_family12 PF18856.1 OAG16462.1 - 1.1 9.8 5.0 0.22 12.1 1.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 adh_short_C2 PF13561.6 OAG16464.1 - 5e-63 212.8 0.0 5.7e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG16464.1 - 9.2e-52 175.3 0.2 1.1e-51 175.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG16464.1 - 3.8e-16 59.5 1.3 5.3e-16 59.0 1.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG16464.1 - 0.053 12.7 0.0 0.077 12.1 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 OAG16464.1 - 0.095 12.6 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2237 PF09996.9 OAG16465.1 - 9.1e-21 74.0 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PUL PF08324.11 OAG16466.1 - 1.5e-67 227.8 0.5 2.1e-67 227.3 0.5 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OAG16466.1 - 4.3e-45 152.6 0.5 7.4e-45 151.8 0.5 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OAG16466.1 - 2.1e-31 107.5 8.8 8.7e-07 29.6 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat V-ATPase_H_N PF03224.14 OAG16466.1 - 0.063 12.6 0.1 0.13 11.5 0.1 1.5 1 1 0 1 1 1 0 V-ATPase subunit H BTB PF00651.31 OAG16468.1 - 1.8e-13 50.7 0.1 1.4e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain HRXXH PF13933.6 OAG16470.1 - 3.2e-105 351.1 0.0 3.2e-105 351.1 0.0 1.3 2 0 0 2 2 2 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAG16470.1 - 1.5e-05 25.5 0.1 4.3e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Sporozoite_P67 PF05642.11 OAG16470.1 - 0.0013 16.9 0.6 0.0016 16.7 0.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Zip PF02535.22 OAG16471.1 - 8.3e-44 150.2 16.8 8.3e-44 150.2 16.8 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter MaoC_dehydrat_N PF13452.6 OAG16472.1 - 0.019 15.1 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase TRAM PF01938.20 OAG16472.1 - 0.11 12.5 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 TRAM domain Fungal_trans PF04082.18 OAG16473.1 - 4.3e-22 78.4 0.8 7.8e-22 77.6 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16473.1 - 7.6e-07 29.2 9.2 7.6e-07 29.2 9.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Catalase PF00199.19 OAG16474.1 - 1.3e-154 515.0 0.2 2.1e-154 514.3 0.2 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG16474.1 - 9.8e-15 54.5 0.1 1.8e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive LPD11 PF18824.1 OAG16474.1 - 0.55 10.4 1.9 5.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Hemerythrin PF01814.23 OAG16475.1 - 7.7e-15 55.7 2.4 1e-14 55.3 2.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sugar_tr PF00083.24 OAG16477.1 - 4.3e-125 418.1 24.6 4.9e-125 417.9 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16477.1 - 3.7e-25 88.6 20.5 3.7e-25 88.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 OAG16478.1 - 2.2e-59 199.8 0.0 3e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG16478.1 - 4e-21 75.1 0.0 4.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 OAG16478.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 OAG16478.1 - 0.022 14.9 0.3 0.051 13.7 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 OAG16478.1 - 0.057 13.5 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain APP_Cu_bd PF12924.7 OAG16478.1 - 0.069 13.9 0.1 1.8 9.3 0.1 2.7 3 0 0 3 3 3 0 Copper-binding of amyloid precursor, CuBD NAD_binding_10 PF13460.6 OAG16479.1 - 1.5e-15 57.6 0.0 2.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG16479.1 - 1.2e-12 47.9 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG16479.1 - 1.1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG16479.1 - 9.4e-05 22.0 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG16479.1 - 0.0015 18.9 0.1 0.0034 17.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG16479.1 - 0.0099 16.0 0.4 0.022 14.9 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 OAG16479.1 - 0.016 14.9 0.1 5.8 6.6 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAG16479.1 - 0.021 15.4 0.2 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAG16479.1 - 0.047 12.7 0.0 0.093 11.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IDO PF01231.18 OAG16479.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.18 OAG16480.1 - 8.8e-15 54.5 0.5 1.5e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16480.1 - 2.5e-07 30.7 16.4 4.6e-07 29.8 16.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG16481.1 - 9.9e-10 37.9 0.3 2.2e-09 36.7 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16481.1 - 9.3e-07 28.9 10.2 1.5e-06 28.2 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PriX PF18689.1 OAG16481.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Primase X Caleosin PF05042.13 OAG16482.1 - 2.6e-75 252.0 0.1 3.2e-75 251.7 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 OAG16482.1 - 0.0083 16.0 0.5 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain IMS PF00817.20 OAG16483.1 - 5.4e-39 133.6 0.0 8.2e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 OAG16483.1 - 1.1e-14 53.7 1.0 2.2e-14 52.7 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 OAG16483.1 - 5e-11 43.3 0.0 1.4e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG16483.1 - 0.063 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif FPP PF05911.11 OAG16486.1 - 0.73 8.0 23.5 1.1 7.4 23.5 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil bZIP_1 PF00170.21 OAG16486.1 - 2.2 8.5 10.8 0.13 12.4 2.9 3.0 1 1 2 3 3 3 0 bZIP transcription factor BRE1 PF08647.11 OAG16486.1 - 6.8 6.8 22.2 0.18 11.9 11.1 3.1 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 OAG16486.1 - 8.1 7.2 17.7 7.2 7.3 9.5 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 OAG16486.1 - 9.2 5.5 25.7 0.047 13.0 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) eIF3m_C_helix PF18005.1 OAG16487.1 - 0.00079 19.1 0.8 0.00079 19.1 0.8 2.5 3 0 0 3 3 3 1 eIF3 subunit M, C-terminal helix AA_permease_2 PF13520.6 OAG16488.1 - 9.2e-61 205.9 53.8 1.2e-60 205.6 53.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG16488.1 - 1.2e-23 83.4 48.0 1.6e-23 83.0 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease Isochorismatase PF00857.20 OAG16489.1 - 1.2e-42 146.1 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Catalase_C PF18011.1 OAG16489.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases CENP-T_C PF15511.6 OAG16490.1 - 3.9e-09 36.6 0.1 4.7e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG16490.1 - 1.1e-05 25.7 0.2 1.3e-05 25.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG16490.1 - 3.7e-05 23.8 0.2 5.4e-05 23.3 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG16490.1 - 5.7e-05 23.3 0.2 9.9e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG16490.1 - 0.00015 22.1 0.1 0.00021 21.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG16490.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG16490.1 - 0.0057 16.6 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 OAG16490.1 - 0.024 14.4 0.2 0.03 14.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 OAG16490.1 - 0.06 13.9 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 OAG16490.1 - 0.067 13.2 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region SNARE_assoc PF09335.11 OAG16491.1 - 0.026 15.0 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Histone PF00125.24 OAG16491.1 - 0.031 14.6 0.6 0.051 13.9 0.6 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TraL PF07178.11 OAG16491.1 - 0.22 12.0 0.5 0.41 11.1 0.5 1.4 1 0 0 1 1 1 0 TraL protein CbtA PF09490.10 OAG16491.1 - 0.47 10.2 2.8 0.61 9.8 0.6 2.0 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) Fibrinogen_BP PF08017.11 OAG16493.1 - 0.1 11.0 0.9 0.18 10.2 0.9 1.3 1 1 0 1 1 1 0 Fibrinogen binding protein PSI_integrin PF17205.3 OAG16494.1 - 0.032 14.0 0.1 0.088 12.6 0.1 1.7 1 0 0 1 1 1 0 Integrin plexin domain HET PF06985.11 OAG16495.1 - 0.0076 16.6 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2138 PF09909.9 OAG16495.1 - 0.12 10.6 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) CDH-cyt PF16010.5 OAG16496.1 - 5.2e-22 78.4 0.1 9.6e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4079 PF13301.6 OAG16496.1 - 0.00013 22.1 2.5 0.02 15.1 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) DUF2427 PF10348.9 OAG16496.1 - 0.44 10.4 7.1 0.094 12.5 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) AAA_12 PF13087.6 OAG16499.1 - 7.6e-40 136.7 0.0 1.1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG16499.1 - 5.2e-25 88.7 1.4 4e-24 85.8 1.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG16499.1 - 1.7e-09 37.7 0.0 3e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG16499.1 - 1.5e-07 31.9 0.0 1.2e-05 25.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OAG16499.1 - 6.4e-06 26.1 0.0 0.0031 17.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG16499.1 - 9.2e-05 22.5 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG16499.1 - 0.00042 19.8 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 OAG16499.1 - 0.0024 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 OAG16499.1 - 0.0052 16.1 0.0 0.089 12.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 OAG16499.1 - 0.064 13.0 0.1 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG16499.1 - 0.066 13.6 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OAG16499.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Helicase_RecD PF05127.14 OAG16499.1 - 0.12 12.2 0.3 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Helicase DnaB_C PF03796.15 OAG16499.1 - 0.16 11.3 0.0 0.55 9.5 0.0 1.8 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 OAG16499.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 OAG16502.1 - 3.9e-82 276.4 0.0 4.6e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KxDL PF10241.9 OAG16503.1 - 2.1e-30 104.9 0.3 2.7e-30 104.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 OAG16503.1 - 0.12 11.8 0.6 0.13 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 OAG16504.1 - 7.7e-54 181.7 0.0 1.7e-39 135.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG16504.1 - 1.3e-09 37.7 0.1 4.4e-09 36.0 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG16504.1 - 2.3e-09 37.9 0.0 0.0017 18.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 OAG16504.1 - 2.5e-09 36.8 0.0 3.6e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 OAG16504.1 - 2.9e-08 34.1 0.4 0.0018 18.5 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_24 PF13479.6 OAG16504.1 - 2.8e-07 30.5 0.0 0.022 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAG16504.1 - 1.1e-06 28.7 0.2 0.0032 17.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG16504.1 - 1.4e-06 27.8 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 OAG16504.1 - 1.9e-06 27.7 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG16504.1 - 2.2e-06 28.2 0.1 0.083 13.4 0.0 4.2 5 0 0 5 5 3 1 AAA domain Mg_chelatase PF01078.21 OAG16504.1 - 4.1e-06 26.3 0.1 0.0082 15.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAG16504.1 - 4.7e-06 26.8 0.0 0.12 12.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 OAG16504.1 - 1.9e-05 24.9 0.0 0.00043 20.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 OAG16504.1 - 2.2e-05 24.8 0.1 0.2 12.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 OAG16504.1 - 5e-05 23.1 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 OAG16504.1 - 0.00018 21.8 0.0 0.76 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 OAG16504.1 - 0.00025 20.3 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase PF06745.13 OAG16504.1 - 0.00028 20.3 0.8 0.034 13.5 0.1 2.8 2 1 1 3 3 3 1 KaiC NACHT PF05729.12 OAG16504.1 - 0.0004 20.4 0.9 0.22 11.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_17 PF13207.6 OAG16504.1 - 0.00042 20.8 0.1 0.34 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG16504.1 - 0.00085 19.0 0.6 1.7 8.2 0.1 3.6 5 0 0 5 5 4 1 AAA domain PhoH PF02562.16 OAG16504.1 - 0.0009 18.7 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 OAG16504.1 - 0.0014 18.3 0.0 0.37 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG16504.1 - 0.0017 18.2 0.0 0.76 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG16504.1 - 0.0017 18.9 0.2 0.46 11.0 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 OAG16504.1 - 0.0021 18.1 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG16504.1 - 0.003 17.1 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 OAG16504.1 - 0.0033 17.4 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OAG16504.1 - 0.0061 16.9 0.1 0.87 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 OAG16504.1 - 0.011 15.4 0.0 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain CDC48_N PF02359.18 OAG16504.1 - 0.021 15.0 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain DUF2075 PF09848.9 OAG16504.1 - 0.023 14.0 0.3 2.1 7.5 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAG16504.1 - 0.04 13.8 0.4 36 4.2 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 OAG16504.1 - 0.045 13.6 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 OAG16504.1 - 0.058 13.1 0.1 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 OAG16504.1 - 0.1 12.0 0.3 11 5.3 0.0 3.3 3 1 1 4 4 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 OAG16504.1 - 0.13 11.4 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SNF2_N PF00176.23 OAG16505.1 - 3.8e-26 91.6 1.6 5.1e-25 87.9 1.5 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OAG16505.1 - 1.6e-14 54.0 0.1 6.3e-14 52.1 0.0 2.0 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-RING_UBOX PF13445.6 OAG16505.1 - 0.0063 16.5 13.1 0.048 13.7 5.1 2.7 2 0 0 2 2 2 2 RING-type zinc-finger FYVE PF01363.21 OAG16505.1 - 3.3 7.9 7.9 5.5 7.2 1.7 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_5 PF14634.6 OAG16505.1 - 3.4 7.7 20.0 3.6 7.6 7.1 2.6 2 0 0 2 2 2 0 zinc-RING finger domain RNA_pol_Rpb5_C PF01191.19 OAG16506.1 - 1.4e-34 117.8 0.2 2.1e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAG16506.1 - 8.2e-27 93.6 0.0 1.6e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain LCM PF04072.14 OAG16507.1 - 1.6e-25 90.1 0.0 3.7e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MAD PF05557.13 OAG16508.1 - 4.2e-65 220.4 74.0 5.7e-65 219.9 74.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Seryl_tRNA_N PF02403.22 OAG16508.1 - 0.0064 16.7 9.4 0.0064 16.7 9.4 7.5 2 2 5 8 8 8 2 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 OAG16508.1 - 0.011 15.8 1.5 0.011 15.8 1.5 11.2 10 1 3 13 13 13 0 Basic region leucine zipper HALZ PF02183.18 OAG16508.1 - 0.044 14.0 0.7 0.044 14.0 0.7 9.2 11 1 1 12 12 12 0 Homeobox associated leucine zipper Spc7 PF08317.11 OAG16508.1 - 4.8 6.0 101.3 0.038 12.9 28.6 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein SHMT PF00464.19 OAG16510.1 - 4.3e-200 664.4 0.1 5.9e-200 663.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase TPR_1 PF00515.28 OAG16512.1 - 4.6e-05 23.0 7.1 0.013 15.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG16512.1 - 0.0011 18.9 6.9 0.12 12.5 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Cucumo_2B PF03263.13 OAG16512.1 - 0.045 14.2 0.7 0.09 13.2 0.7 1.5 1 0 0 1 1 1 0 Cucumovirus protein 2B TPR_14 PF13428.6 OAG16512.1 - 0.15 13.0 1.2 39 5.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Mcp5_PH PF12814.7 OAG16514.1 - 6.6e-46 155.4 0.0 1.2e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 OAG16514.1 - 0.1 13.0 10.7 0.26 11.7 10.7 1.7 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 OAG16514.1 - 0.19 11.8 18.2 0.3 11.1 11.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mycoplasma_p37 PF06646.11 OAG16514.1 - 0.26 10.5 0.8 0.43 9.8 0.8 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 Golgin_A5 PF09787.9 OAG16514.1 - 0.35 10.3 12.9 0.64 9.4 12.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 OAG16514.1 - 1.4 9.5 11.9 3.9 8.0 11.9 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 OAG16514.1 - 2.8 8.0 11.7 0.093 12.8 5.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 OAG16514.1 - 6.6 7.2 14.4 0.93 9.9 3.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) AMP-binding PF00501.28 OAG16516.1 - 6.1e-78 262.3 0.0 7.6e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG16516.1 - 9e-16 58.6 0.1 1.8e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 OAG16517.1 - 4e-16 59.8 0.0 1.2e-15 58.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 OAG16517.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 SAD/SRA domain Dioxygenase_C PF00775.21 OAG16518.1 - 1.5e-42 145.1 0.0 2.5e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Acyl-CoA_dh_1 PF00441.24 OAG16518.1 - 1.4e-41 142.2 0.4 2.4e-41 141.4 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG16518.1 - 8.9e-34 116.6 0.0 2.3e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG16518.1 - 1.7e-27 95.4 0.3 3.6e-27 94.4 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Dioxygenase_N PF04444.14 OAG16518.1 - 1.1e-25 89.3 0.1 2.2e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Acyl-CoA_dh_2 PF08028.11 OAG16518.1 - 9.5e-16 58.3 0.1 1.8e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CMD PF02627.20 OAG16518.1 - 6.4e-10 38.9 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family HpaB_N PF11794.8 OAG16518.1 - 1.3e-05 25.0 0.5 3.5e-05 23.6 0.5 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CarboxypepD_reg PF13620.6 OAG16518.1 - 0.044 14.0 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Lactonase PF10282.9 OAG16519.1 - 6.7e-13 48.6 0.0 2.6e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.7 OAG16520.1 - 5.9e-14 53.2 0.0 1.4e-13 52.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG16520.1 - 2.7e-13 50.2 0.0 7.4e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG16520.1 - 7.2e-08 32.0 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG16520.1 - 4e-06 25.7 0.0 5.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family EthD PF07110.11 OAG16520.1 - 1e-05 26.5 0.2 0.062 14.4 0.1 3.0 2 0 0 2 2 2 2 EthD domain Esterase PF00756.20 OAG16520.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase TilS_C PF11734.8 OAG16520.1 - 0.32 10.5 1.5 2 7.9 1.5 2.3 1 1 0 1 1 1 0 TilS substrate C-terminal domain MscL PF01741.18 OAG16521.1 - 7.5e-10 39.2 0.0 9.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL WD40 PF00400.32 OAG16523.1 - 4.1e-15 55.9 7.5 0.16 12.9 0.5 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat CDC45 PF02724.14 OAG16523.1 - 0.00041 18.8 3.0 0.00041 18.8 3.0 1.4 2 0 0 2 2 2 1 CDC45-like protein ANAPC4_WD40 PF12894.7 OAG16523.1 - 0.033 14.5 0.1 15 6.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpc4 PF05132.14 OAG16523.1 - 3.5 8.0 10.5 11 6.4 4.5 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 SKG6 PF08693.10 OAG16524.1 - 0.0065 15.9 5.3 0.011 15.1 5.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GT87 PF09594.10 OAG16524.1 - 0.028 14.1 0.6 0.044 13.5 0.6 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 Mito_fiss_reg PF05308.11 OAG16524.1 - 3.7 7.6 6.1 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator SKG6 PF08693.10 OAG16525.1 - 0.0017 17.7 1.5 0.0032 16.9 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 OAG16525.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A Romo1 PF10247.9 OAG16525.1 - 0.12 12.8 1.9 0.21 11.9 1.9 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 VSP PF03302.13 OAG16525.1 - 0.2 10.5 0.2 0.25 10.2 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Gram_pos_anchor PF00746.21 OAG16525.1 - 1.1 9.3 3.8 0.7 9.9 1.3 2.0 1 1 1 2 2 2 0 LPXTG cell wall anchor motif Popeye PF04831.13 OAG16526.1 - 1.1 9.4 9.9 0.054 13.7 3.9 2.0 2 0 0 2 2 2 0 Popeye protein conserved region AA_permease PF00324.21 OAG16528.1 - 3.4e-124 415.0 46.4 4.1e-124 414.8 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG16528.1 - 1.2e-29 103.5 51.9 1.5e-29 103.1 51.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAG16528.1 - 0.068 12.0 5.3 0.47 9.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Hydrophobin_2 PF06766.11 OAG16529.1 - 5.7e-22 77.4 11.7 7.8e-22 77.0 11.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NRIP1_repr_1 PF15687.5 OAG16530.1 - 0.053 13.2 0.9 0.095 12.4 0.9 1.3 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 ApbA_C PF08546.11 OAG16531.1 - 8.3e-28 97.1 0.1 3e-27 95.3 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG16531.1 - 4.9e-27 94.5 0.0 6.9e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Nif11 PF07862.11 OAG16531.1 - 0.11 12.8 0.1 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Nif11 domain Asparaginase_C PF17763.1 OAG16531.1 - 0.21 11.8 0.7 5.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain F-box-like PF12937.7 OAG16532.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16532.1 - 0.00026 20.8 0.2 0.0025 17.6 0.0 2.7 3 0 0 3 3 3 1 F-box domain Sec6 PF06046.13 OAG16532.1 - 0.097 11.0 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 CRS1_YhbY PF01985.21 OAG16532.1 - 0.1 12.8 0.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain Elongin_A PF06881.11 OAG16533.1 - 3.1e-33 114.4 1.5 5.6e-33 113.6 1.5 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Myb_DNA-bind_3 PF12776.7 OAG16533.1 - 0.056 14.4 0.8 0.12 13.3 0.8 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Bap31_Bap29_C PF18035.1 OAG16533.1 - 0.28 11.2 8.4 0.52 10.3 8.4 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain THOC7 PF05615.13 OAG16534.1 - 2.5e-27 95.7 7.5 2.5e-27 95.7 7.5 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 CALCOCO1 PF07888.11 OAG16534.1 - 0.00071 18.6 19.7 0.0012 17.8 19.7 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.15 OAG16534.1 - 0.0033 17.2 1.4 0.0033 17.2 1.4 2.7 2 1 1 3 3 3 1 Septum formation initiator PNKP_ligase PF16542.5 OAG16534.1 - 0.011 15.3 0.4 0.015 14.8 0.4 1.2 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain FlaC_arch PF05377.11 OAG16534.1 - 2.2 8.7 4.8 11 6.6 0.6 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 OAG16534.1 - 2.6 8.2 6.1 4.7 7.4 0.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 OAG16534.1 - 3.8 6.8 7.5 5.5 6.2 7.5 1.3 1 0 0 1 1 1 0 FAM76 protein HAUS5 PF14817.6 OAG16534.1 - 9.2 4.9 17.9 1.6 7.4 8.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 TBCA PF02970.16 OAG16535.1 - 4.9e-26 90.9 10.6 4.9e-26 90.9 10.6 1.6 1 1 1 2 2 2 1 Tubulin binding cofactor A Snf7 PF03357.21 OAG16535.1 - 0.024 14.3 8.3 0.018 14.6 7.2 1.3 1 1 0 1 1 1 0 Snf7 FapA PF03961.13 OAG16535.1 - 0.038 12.6 7.2 0.04 12.5 7.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 OAG16535.1 - 0.056 12.3 10.2 0.033 13.1 3.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAG16535.1 - 0.1 11.9 8.9 0.11 11.8 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2570 PF10828.8 OAG16535.1 - 0.14 12.0 6.2 0.23 11.3 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4398 PF14346.6 OAG16535.1 - 0.35 11.5 13.1 0.95 10.1 3.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Tho2 PF11262.8 OAG16535.1 - 0.63 9.2 6.8 0.73 9.0 6.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1910 PF08928.10 OAG16535.1 - 0.75 9.8 5.6 0.97 9.4 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Med8 PF10232.9 OAG16535.1 - 0.98 9.0 8.9 1.1 8.8 8.9 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 JIP_LZII PF16471.5 OAG16535.1 - 1.2 9.3 8.6 1.1 9.5 3.3 2.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF5327 PF17261.2 OAG16535.1 - 1.2 9.9 7.9 0.74 10.6 1.3 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5327) DUF1690 PF07956.11 OAG16535.1 - 1.8 9.0 9.3 3.6 8.0 9.3 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) MCM PF00493.23 OAG16536.1 - 6.4e-100 332.8 0.0 9.7e-100 332.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG16536.1 - 1.7e-37 128.1 1.0 3.7e-37 127.0 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG16536.1 - 2.7e-29 101.4 1.8 7.2e-29 100.1 1.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG16536.1 - 1.7e-15 57.5 0.0 6e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 OAG16536.1 - 5.2e-06 26.5 0.1 2.5e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG16536.1 - 9.9e-06 25.1 0.0 0.00025 20.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG16536.1 - 0.00032 20.5 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG16536.1 - 0.066 12.9 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Elf1 PF05129.13 OAG16536.1 - 0.13 12.3 0.4 0.33 11.0 0.4 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like MFS_1 PF07690.16 OAG16539.1 - 9.4e-17 61.0 58.6 1e-15 57.5 25.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG16539.1 - 1.1e-10 40.6 13.3 1.1e-10 40.6 13.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Vac7 PF12751.7 OAG16540.1 - 3.5e-116 388.8 24.5 6.8e-105 351.6 3.1 3.4 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 Pox_I5 PF04713.12 OAG16540.1 - 0.14 12.3 0.6 0.24 11.4 0.6 1.3 1 0 0 1 1 1 0 Poxvirus protein I5 CBM-like PF14683.6 OAG16541.1 - 1.3e-34 119.5 0.1 4.2e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG16541.1 - 2.9e-16 59.0 1.8 1.2e-15 57.1 1.8 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG16541.1 - 7.7e-07 29.3 0.6 4.5e-06 26.8 0.2 2.5 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 OAG16541.1 - 0.00024 21.2 0.1 0.00079 19.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 OAG16541.1 - 0.022 14.7 0.4 0.7 9.9 0.4 2.8 2 1 0 2 2 2 0 CarboxypepD_reg-like domain RhgB_N PF09284.10 OAG16541.1 - 0.042 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Dioxygenase_C PF00775.21 OAG16541.1 - 0.5 9.8 4.6 0.16 11.4 0.4 2.2 3 0 0 3 3 3 0 Dioxygenase SSF PF00474.17 OAG16542.1 - 1.5e-18 66.9 30.3 2.5e-18 66.2 30.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DMRT-like PF15791.5 OAG16543.1 - 0.095 13.1 4.3 0.44 11.0 3.5 2.2 1 1 1 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 DUF5546 PF17700.1 OAG16545.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5546) DEAD PF00270.29 OAG16546.1 - 1.1e-36 126.2 0.2 2e-36 125.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG16546.1 - 1.2e-29 102.8 0.1 4.4e-28 97.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG16546.1 - 0.00068 19.7 0.0 0.0027 17.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG16546.1 - 0.0012 19.2 2.6 0.0029 18.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 OAG16546.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Mucin PF01456.17 OAG16546.1 - 0.041 13.9 9.8 0.075 13.0 9.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RNA_polI_A34 PF08208.11 OAG16546.1 - 0.14 12.2 7.2 8 6.5 5.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Med3 PF11593.8 OAG16546.1 - 4.2 6.5 9.4 7.8 5.6 9.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5326 PF17260.2 OAG16555.1 - 0.012 15.7 0.2 0.022 14.9 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Ldr_toxin PF13940.6 OAG16557.1 - 0.01 15.9 1.5 0.019 15.0 1.5 1.5 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system Glyco_hydro_64 PF16483.5 OAG16559.1 - 1.5e-141 472.0 0.1 1.9e-141 471.6 0.1 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF2502 PF10697.9 OAG16559.1 - 0.011 16.1 0.2 0.044 14.1 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Fungal_trans PF04082.18 OAG16560.1 - 8.9e-09 34.7 0.1 1.6e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4149 PF13664.6 OAG16561.1 - 2.2e-20 72.9 2.0 2.2e-20 72.9 2.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) Erg28 PF03694.13 OAG16561.1 - 0.043 14.2 0.1 0.071 13.5 0.1 1.3 1 0 0 1 1 1 0 Erg28 like protein Lipase_GDSL_2 PF13472.6 OAG16562.1 - 1.2e-11 45.3 2.0 1.7e-11 44.8 2.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG16562.1 - 6.3e-07 29.6 0.1 9.4e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank_2 PF12796.7 OAG16563.1 - 2.8e-24 85.5 6.5 3.5e-10 40.3 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG16563.1 - 4e-19 68.7 0.6 4e-06 27.3 0.0 6.3 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG16563.1 - 2e-18 64.5 5.6 0.0011 19.3 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OAG16563.1 - 2.6e-10 40.3 8.4 0.037 14.3 0.0 6.9 3 1 4 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG16563.1 - 3e-10 40.1 12.7 0.088 13.3 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat Nop14 PF04147.12 OAG16563.1 - 0.15 10.2 8.7 0.22 9.7 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAG16563.1 - 0.53 9.7 8.0 0.83 9.0 8.0 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 OAG16563.1 - 1.4 8.8 6.5 2.4 8.0 6.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 OAG16563.1 - 4 6.7 11.5 7.1 5.9 11.5 1.3 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 OAG16565.1 - 6.5e-33 114.1 41.8 1.7e-32 112.7 41.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Beta_helix_2 PF18835.1 OAG16565.1 - 0.12 12.1 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Lipase_3 PF01764.25 OAG16566.1 - 2.6e-06 27.4 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 OAG16566.1 - 0.0034 17.2 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 OAG16566.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 OAG16566.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_3 PF13302.7 OAG16567.1 - 8e-15 55.7 0.0 9.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG16567.1 - 0.00017 21.8 0.0 0.00065 19.9 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG16567.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Fungal_trans PF04082.18 OAG16568.1 - 3.4e-08 32.8 0.0 5.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16568.1 - 2.4e-07 30.7 9.9 4.8e-07 29.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IDO PF01231.18 OAG16569.1 - 6e-116 387.8 0.0 7.1e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase BTB PF00651.31 OAG16570.1 - 1.7e-10 41.1 0.0 7.7e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Aminotran_5 PF00266.19 OAG16570.1 - 2.6e-06 26.6 0.0 4.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cytochrom_B561 PF03188.16 OAG16571.1 - 1.6e-17 63.9 5.9 1.6e-17 63.9 5.9 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 SdpI PF13630.6 OAG16571.1 - 0.023 14.8 1.7 0.023 14.8 1.7 3.0 3 2 0 3 3 3 0 SdpI/YhfL protein family 7TM_GPCR_Srz PF10325.9 OAG16571.1 - 0.23 10.8 3.6 0.074 12.4 0.4 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz SLATT_3 PF18184.1 OAG16571.1 - 0.32 11.1 1.3 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF2306 PF10067.9 OAG16571.1 - 1.6 8.9 13.2 0.051 13.8 3.9 2.6 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) DUF4079 PF13301.6 OAG16571.1 - 8.8 6.5 16.7 7.8 6.6 8.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) HATPase_c PF02518.26 OAG16572.1 - 1.1e-26 93.6 0.0 2.2e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG16572.1 - 1.2e-17 63.7 0.2 3.1e-17 62.4 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAG16572.1 - 2.2e-17 63.2 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 OAG16572.1 - 9.8e-17 61.0 2.0 2.2e-08 34.2 0.5 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 OAG16572.1 - 1.7e-09 37.7 0.0 0.00037 20.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAG16572.1 - 4.1e-07 30.2 0.1 0.00043 20.5 0.0 3.6 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 OAG16572.1 - 5.8e-07 29.7 0.0 0.0056 16.9 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.7 OAG16572.1 - 8.8e-05 22.4 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAN_4 PF14295.6 OAG16575.1 - 4.9e-16 58.4 5.0 1.4e-08 34.5 1.3 2.5 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 OAG16575.1 - 6.9e-06 25.8 4.9 0.04 13.7 0.1 2.9 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.26 OAG16575.1 - 2.1e-05 24.4 1.5 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 OAG16575.1 - 0.26 11.4 4.4 2.3 8.4 0.4 2.8 2 0 0 2 2 2 0 PAN-like domain Dicty_CTDC PF00526.18 OAG16575.1 - 2.9 7.9 11.2 1.1 9.2 1.0 3.3 3 0 0 3 3 3 0 Dictyostelium (slime mold) repeat NPV_P10 PF05531.12 OAG16577.1 - 0.034 14.6 4.0 27 5.3 0.0 5.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 OAG16577.1 - 0.039 11.9 10.8 1.4 6.8 0.1 3.7 4 1 0 4 4 4 0 Prominin RSN1_7TM PF02714.15 OAG16577.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate COG2 PF06148.11 OAG16577.1 - 0.16 12.0 3.9 33 4.6 0.2 5.2 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 OAG16577.1 - 0.46 10.5 16.9 2.1 8.4 1.2 5.7 7 0 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nmad5 PF18757.1 OAG16577.1 - 1.7 8.8 9.7 0.53 10.5 0.2 3.5 4 0 0 4 4 4 0 Nucleotide modification associated domain 5 BLOC1S3 PF15753.5 OAG16577.1 - 3.1 7.9 7.9 1.3 9.1 0.0 3.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF3040 PF11239.8 OAG16577.1 - 4.1 7.8 6.5 0.85 9.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Antigen_Bd37 PF11641.8 OAG16577.1 - 6.6 6.2 7.8 19 4.7 1.5 3.1 2 1 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Reprolysin_4 PF13583.6 OAG16578.1 - 1.3e-05 25.0 0.0 1.9e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG16578.1 - 3.8e-05 23.9 0.0 6.1e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 OAG16578.1 - 0.00021 21.0 0.0 0.00058 19.5 0.0 1.5 1 1 1 2 2 2 1 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 OAG16578.1 - 0.00052 19.3 0.1 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Met-zincin Peptidase_M10 PF00413.24 OAG16578.1 - 0.0018 18.1 1.9 0.0029 17.5 0.7 2.0 2 1 0 2 2 2 1 Matrixin Reprolysin_2 PF13574.6 OAG16578.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAG16578.1 - 0.0026 18.3 0.3 0.0052 17.3 0.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OAG16578.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 OAG16578.1 - 0.045 13.7 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Astacin PF01400.24 OAG16578.1 - 0.47 10.0 2.1 1.6 8.3 2.1 1.8 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) IBR PF01485.21 OAG16580.1 - 8.4e-24 83.6 48.1 1.5e-13 50.7 7.6 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAG16580.1 - 1.6e-05 24.7 3.7 1.6e-05 24.7 3.7 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG16580.1 - 6.2e-05 23.2 3.7 6.2e-05 23.2 3.7 4.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG16580.1 - 0.00041 20.1 5.8 0.00041 20.1 5.8 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG16580.1 - 0.001 19.0 4.2 0.001 19.0 4.2 3.7 3 0 0 3 3 3 1 RING-type zinc-finger Trp_syntA PF00290.20 OAG16580.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain zf-RING_14 PF17978.1 OAG16580.1 - 0.041 14.3 1.5 0.041 14.3 1.5 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG16580.1 - 2.4 8.4 33.4 0.43 10.8 3.4 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING DNA_ligase_ZBD PF03119.16 OAG16580.1 - 3.6 7.7 11.4 2.6 8.2 0.2 3.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain W2 PF02020.18 OAG16581.1 - 1.1e-11 44.7 7.7 4.4e-11 42.8 7.4 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAG16581.1 - 4.1e-11 42.1 13.7 4e-05 23.2 3.7 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAG16581.1 - 1.8e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OAG16581.1 - 8.3e-05 23.0 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAG16581.1 - 0.00031 20.4 9.3 0.085 12.6 0.8 3.4 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 OAG16581.1 - 0.019 13.1 1.3 0.072 11.2 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) HSF_DNA-bind PF00447.17 OAG16582.1 - 2.2e-31 108.3 1.7 4.1e-31 107.5 1.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 OAG16582.1 - 2.1e-22 79.4 0.0 4.3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Redoxin PF08534.10 OAG16583.1 - 4.7e-28 97.8 0.0 5.6e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG16583.1 - 2.1e-07 30.9 0.0 2.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FmdA_AmdA PF03069.15 OAG16584.1 - 1.8e-175 583.2 0.0 2.2e-156 520.4 0.0 2.0 2 0 0 2 2 2 2 Acetamidase/Formamidase family EI24 PF07264.11 OAG16585.1 - 7e-14 52.5 0.0 6.3e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 OAG16586.1 - 3.9e-34 117.6 0.0 8.9e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Patatin PF01734.22 OAG16588.1 - 1.7e-23 83.9 0.3 2.6e-22 80.0 0.3 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase BTB PF00651.31 OAG16591.1 - 1.7e-20 73.3 0.0 1.2e-08 35.1 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain TMA7 PF09072.10 OAG16591.1 - 0.055 14.3 0.3 0.11 13.4 0.3 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 Peptidase_S8 PF00082.22 OAG16592.1 - 2e-37 129.1 13.0 3e-37 128.5 13.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG16592.1 - 7.9e-18 64.9 1.1 2e-17 63.6 1.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 OAG16593.1 - 7e-117 389.7 0.3 1.2e-116 389.0 0.3 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OAG16593.1 - 5.7e-10 39.2 1.3 2.7e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OAG16593.1 - 1.4e-08 35.1 0.1 6.2e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OAG16593.1 - 0.00042 21.1 0.8 6 7.9 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Tli4_N PF18443.1 OAG16593.1 - 0.7 10.3 2.1 1.5 9.2 0.8 2.2 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Cys_rich_VLP PF14194.6 OAG16594.1 - 1.2 9.3 4.1 0.57 10.4 1.5 1.9 2 1 0 2 2 2 0 Cysteine-rich VLP HET PF06985.11 OAG16595.1 - 6.1e-27 94.8 1.0 4.9e-26 91.8 1.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG16596.1 - 3e-21 75.6 0.0 4.5e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16596.1 - 8.5e-11 41.8 23.2 4.9e-08 33.0 11.3 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM217 PF15344.6 OAG16596.1 - 0.2 11.5 0.5 0.39 10.6 0.5 1.4 1 0 0 1 1 1 0 FAM217 family Apolipoprotein PF01442.18 OAG16600.1 - 0.0033 17.3 0.0 3.8 7.4 0.0 3.3 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain ATG_C PF09333.11 OAG16600.1 - 0.0047 17.2 1.1 0.054 13.8 0.3 2.9 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain T3SSipB PF16535.5 OAG16600.1 - 0.016 15.7 1.3 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Perilipin PF03036.16 OAG16600.1 - 0.028 13.4 0.6 0.028 13.4 0.6 3.5 3 1 1 4 4 4 0 Perilipin family Phasin PF05597.11 OAG16600.1 - 0.029 14.4 4.1 4.4 7.3 0.2 3.8 4 1 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 OAG16600.1 - 0.63 10.5 0.1 0.63 10.5 0.1 4.6 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein TOBE PF03459.17 OAG16600.1 - 2 8.8 9.4 4.1 7.8 0.7 3.6 4 0 0 4 4 4 0 TOBE domain WD40 PF00400.32 OAG16602.1 - 1.1e-24 86.2 9.6 2.7e-08 34.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG16602.1 - 7.7e-09 35.7 0.9 0.011 16.0 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG16602.1 - 1.5e-06 27.5 0.1 0.003 16.6 0.0 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG16602.1 - 0.017 13.8 1.1 3.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MFS_1 PF07690.16 OAG16603.1 - 1.6e-35 122.7 30.0 1.6e-33 116.1 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 OAG16603.1 - 0.0078 16.3 0.1 0.63 10.1 0.0 2.5 2 0 0 2 2 2 1 PgaD-like protein Nsp2a_N PF17896.1 OAG16603.1 - 0.056 12.6 0.5 0.66 9.1 0.2 2.0 2 0 0 2 2 2 0 Replicase polyprotein 1a N-terminal domain Epimerase PF01370.21 OAG16604.1 - 3.5e-12 46.3 0.0 5.2e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG16604.1 - 1.9e-06 27.9 0.0 4.3e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAG16604.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAG16604.1 - 0.016 14.9 0.3 0.025 14.2 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 OAG16604.1 - 0.018 14.6 0.3 0.28 10.7 0.3 2.4 1 1 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG16604.1 - 0.068 12.6 0.2 0.1 11.9 0.2 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cupin_2 PF07883.11 OAG16605.1 - 1.6e-15 56.5 0.2 3.2e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG16605.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 OAG16605.1 - 7.9e-06 26.1 0.1 1.5e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.12 OAG16605.1 - 6.7e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAG16605.1 - 0.00026 20.7 0.1 0.00029 20.6 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 OAG16605.1 - 0.0007 19.2 0.1 0.00088 18.9 0.1 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 OAG16605.1 - 0.025 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase SsgA PF04686.12 OAG16605.1 - 0.065 13.2 0.1 0.22 11.5 0.1 1.8 1 1 1 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA ABC_membrane PF00664.23 OAG16606.1 - 9.3e-50 169.8 10.4 1.3e-49 169.3 10.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG16606.1 - 4.6e-35 121.1 0.0 1.5e-34 119.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OAG16606.1 - 1.3e-05 24.7 0.0 3.2e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG16606.1 - 0.00024 21.4 0.6 0.0027 18.0 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG16606.1 - 0.0044 17.4 0.4 0.017 15.5 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 OAG16606.1 - 0.0082 15.9 0.3 0.084 12.6 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 OAG16606.1 - 0.0084 16.5 0.2 0.085 13.3 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 OAG16606.1 - 0.022 14.9 0.7 0.19 11.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 OAG16606.1 - 0.025 14.3 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAG16606.1 - 0.073 12.8 0.1 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG16606.1 - 0.12 11.9 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAG16606.1 - 0.15 12.3 0.8 1.7 9.0 0.8 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RTC PF01137.21 OAG16607.1 - 1.2e-63 214.3 0.2 1.6e-63 213.9 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase FAD_binding_1 PF00667.20 OAG16608.1 - 1.8e-48 165.0 0.0 2.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAG16608.1 - 5.2e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain F-box-like PF12937.7 OAG16609.1 - 1.5e-07 31.2 0.1 3.3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16609.1 - 0.018 14.9 0.1 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 F-box domain MOSC PF03473.17 OAG16610.1 - 5.2e-29 100.9 0.0 8.5e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG16610.1 - 4.3e-09 36.3 0.0 5.1e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Allantoicase PF03561.15 OAG16611.1 - 4.5e-92 305.6 0.1 1.4e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 OAG16612.1 - 1.2e-30 105.8 1.3 2.4e-30 104.9 1.3 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 OAG16612.1 - 4.3e-15 56.1 0.1 2.8e-14 53.4 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG16612.1 - 7.9e-12 45.5 0.0 1.3e-06 28.8 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG16612.1 - 1.2e-11 44.5 0.0 9.8e-06 25.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG16612.1 - 1e-09 38.4 0.0 6e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG16612.1 - 2.7e-07 30.4 0.2 0.00073 19.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat HATPase_c PF02518.26 OAG16613.1 - 8.8e-31 106.7 0.0 1.8e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG16613.1 - 4e-20 71.6 0.0 2.5e-19 69.1 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAG16613.1 - 9e-18 64.5 0.0 2.2e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 OAG16613.1 - 3.1e-12 47.2 0.3 2.1e-10 41.3 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 OAG16613.1 - 4.6e-10 39.3 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.6 OAG16613.1 - 1.7e-08 34.9 0.0 6.1e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAG16613.1 - 5.5e-07 30.3 0.0 1.6e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 OAG16613.1 - 0.00078 19.4 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain GAF_3 PF13492.6 OAG16613.1 - 0.0016 18.8 0.0 0.0056 17.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain RsgA_GTPase PF03193.16 OAG16613.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Hydrolase_4 PF12146.8 OAG16615.1 - 6e-27 94.4 0.1 4.6e-26 91.6 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG16615.1 - 7.1e-22 78.3 0.0 8.6e-19 68.2 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG16615.1 - 7.5e-18 65.9 0.0 1e-17 65.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAG16615.1 - 5.4e-07 29.6 0.1 0.089 12.6 0.0 3.0 1 1 1 3 3 3 2 Phospholipase/Carboxylesterase Ndr PF03096.14 OAG16615.1 - 6.7e-06 25.0 0.0 8.3e-06 24.7 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 OAG16615.1 - 2.3e-05 24.2 0.1 0.00051 19.8 0.2 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG16615.1 - 3.4e-05 23.4 0.1 0.051 13.0 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 OAG16615.1 - 3.6e-05 22.5 0.6 0.00024 19.8 0.0 2.0 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG16615.1 - 0.00012 21.1 0.1 0.00033 19.7 0.1 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 OAG16615.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 OAG16615.1 - 0.00061 19.7 0.1 0.006 16.5 0.0 2.0 1 1 1 2 2 2 1 Serine hydrolase DUF676 PF05057.14 OAG16615.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DLH PF01738.18 OAG16615.1 - 0.0073 15.9 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG16615.1 - 0.014 15.3 0.1 0.017 14.9 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG16615.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.10 OAG16615.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 OAG16615.1 - 0.084 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 OAG16615.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 OAG16615.1 - 0.12 11.9 0.0 0.78 9.2 0.0 1.9 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Acyl_transf_2 PF02273.15 OAG16615.1 - 0.12 11.5 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Acyl transferase DUF915 PF06028.11 OAG16615.1 - 0.15 11.3 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 OAG16615.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cyt-b5 PF00173.28 OAG16617.1 - 3e-18 65.7 0.3 3.4e-18 65.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TSP9 PF11493.8 OAG16617.1 - 0.018 15.7 0.1 0.022 15.4 0.1 1.1 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 GH131_N PF18271.1 OAG16619.1 - 1.9e-61 208.0 6.3 2.1e-61 207.8 6.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 OAG16619.1 - 0.0015 18.5 7.2 0.0033 17.3 7.2 1.6 1 1 0 1 1 1 1 Polysaccharide lyase TetR_N PF00440.23 OAG16619.1 - 0.14 11.9 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family SWI-SNF_Ssr4 PF08549.10 OAG16621.1 - 3.6e-177 591.2 36.1 4.4e-175 584.3 36.1 2.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Acyl_transf_3 PF01757.22 OAG16623.1 - 1.3e-13 50.7 22.8 2.2e-13 50.0 22.6 1.5 1 1 0 1 1 1 1 Acyltransferase family Band_7 PF01145.25 OAG16624.1 - 1.4e-30 106.6 4.3 2.5e-30 105.8 4.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OAG16624.1 - 0.0092 15.7 0.5 0.018 14.8 0.5 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Dak1_2 PF13684.6 OAG16624.1 - 0.016 14.3 0.8 0.023 13.8 0.8 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Kinesin_assoc PF16183.5 OAG16624.1 - 0.63 10.2 3.8 0.47 10.6 1.5 1.8 1 1 0 2 2 2 0 Kinesin-associated SesA PF17107.5 OAG16625.1 - 7e-07 29.5 1.5 1.2e-06 28.7 1.5 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 OAG16625.1 - 8.8e-05 22.0 0.6 0.00017 21.0 0.6 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 OAG16625.1 - 0.0018 18.6 0.2 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OAG16625.1 - 0.0023 18.5 0.0 0.0052 17.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG16625.1 - 0.0052 17.2 0.1 0.025 15.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAG16625.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG16625.1 - 0.092 13.4 0.1 0.27 11.9 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Rx_N PF18052.1 OAG16625.1 - 0.13 12.6 3.2 0.14 12.5 0.5 2.4 3 0 0 3 3 3 0 Rx N-terminal domain DUF1768 PF08719.11 OAG16626.1 - 4.7e-27 95.2 0.0 5.8e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) LRR19-TM PF15176.6 OAG16626.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain OST3_OST6 PF04756.13 OAG16628.1 - 4.6e-104 347.9 0.0 5.2e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family QCR10 PF09796.9 OAG16628.1 - 0.074 13.1 4.0 1.6 8.8 0.3 2.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HXXEE PF13787.6 OAG16628.1 - 0.15 12.8 0.3 0.15 12.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif YqhR PF11085.8 OAG16628.1 - 0.6 10.0 5.0 0.78 9.6 0.8 2.2 2 0 0 2 2 2 0 Conserved membrane protein YqhR CPBP PF02517.16 OAG16628.1 - 1.1 9.7 5.5 6.6 7.2 5.5 2.1 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease DUF4449 PF14613.6 OAG16629.1 - 1.4e-07 31.8 3.4 2.9e-07 30.7 0.1 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) AbiH PF14253.6 OAG16629.1 - 0.0039 17.1 1.9 0.012 15.5 1.0 2.0 2 0 0 2 2 2 1 Bacteriophage abortive infection AbiH Senescence PF06911.12 OAG16629.1 - 0.033 14.5 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 Senescence-associated protein PB1 PF00564.24 OAG16629.1 - 0.042 13.8 0.2 0.83 9.6 0.1 2.6 1 1 1 2 2 2 0 PB1 domain Tricorn_C1 PF14684.6 OAG16629.1 - 0.046 13.8 0.1 0.23 11.6 0.1 2.3 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF1828 PF08861.10 OAG16629.1 - 0.08 13.2 0.3 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1828 T3SS_basalb_I PF17001.5 OAG16629.1 - 0.15 12.7 1.1 0.61 10.7 0.3 2.5 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF4208 PF13907.6 OAG16629.1 - 0.47 10.9 2.7 3.7 8.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Malic_M PF03949.15 OAG16630.1 - 1.7e-92 309.3 0.0 2.2e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAG16630.1 - 3.1e-61 206.3 0.0 6.6e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain FGF-BP1 PF06473.12 OAG16631.1 - 0.83 9.4 2.8 1 9.2 2.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Rhomboid_SP PF12595.8 OAG16632.1 - 0.1 11.9 0.3 1.6 8.1 0.0 1.9 1 1 1 2 2 2 0 Rhomboid serine protease FAM101 PF15068.6 OAG16632.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 FAM101 family Patatin PF01734.22 OAG16633.1 - 3.6e-14 53.4 0.0 1.7e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase ApbA_C PF08546.11 OAG16635.1 - 7.3e-27 94.0 0.0 9.6e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG16635.1 - 2.7e-05 23.9 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Ribosomal_L44 PF00935.19 OAG16636.1 - 4.2e-36 123.3 12.1 6.6e-36 122.6 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 MSC PF09402.10 OAG16637.1 - 6.3e-100 334.9 0.0 9.3e-100 334.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 OAG16637.1 - 2.7e-14 52.6 0.0 5.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain NifQ PF04891.12 OAG16637.1 - 6.5 7.1 6.1 4.6 7.6 0.1 2.4 2 0 0 2 2 2 0 NifQ Pkinase PF00069.25 OAG16638.1 - 4.5e-14 52.4 0.0 1.1e-13 51.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16638.1 - 2.1e-06 27.2 0.0 5.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase LINES_N PF14694.6 OAG16638.1 - 0.026 14.0 0.2 0.039 13.4 0.2 1.1 1 0 0 1 1 1 0 Lines N-terminus Sugar_tr PF00083.24 OAG16640.1 - 8.9e-76 255.6 20.2 1.1e-75 255.3 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16640.1 - 1.4e-25 89.9 20.5 2.3e-25 89.3 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3624 PF12292.8 OAG16640.1 - 4 7.9 13.1 16 6.0 1.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) EthD PF07110.11 OAG16643.1 - 2.2e-19 70.4 0.2 2.8e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG16643.1 - 1.8e-07 31.6 0.1 2.2e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase ATP-grasp PF02222.22 OAG16643.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 1 0 1 1 1 0 ATP-grasp domain adh_short PF00106.25 OAG16644.1 - 8.2e-33 113.5 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16644.1 - 1.2e-23 83.9 0.0 1.5e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG16644.1 - 2.4e-05 24.3 0.0 9.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 KR domain MT0933_antitox PF14013.6 OAG16645.1 - 0.033 14.5 2.7 0.055 13.8 2.7 1.3 1 0 0 1 1 1 0 MT0933-like antitoxin protein DUF883 PF05957.13 OAG16645.1 - 0.067 13.8 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MINDY_DUB PF04424.13 OAG16647.1 - 0.15 12.0 0.0 1 9.4 0.0 2.4 2 1 0 2 2 2 0 MINDY deubiquitinase AAA PF00004.29 OAG16648.1 - 2.2e-15 57.3 0.0 4e-06 27.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAG16648.1 - 0.02 14.9 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 BCS1 N terminal IPT PF01745.16 OAG16648.1 - 0.09 12.2 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase AAA_16 PF13191.6 OAG16648.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 OAG16648.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 OAG16648.1 - 0.17 11.0 0.2 0.37 9.8 0.2 1.4 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.6 OAG16648.1 - 0.65 8.6 2.5 0.35 9.4 0.2 1.6 2 0 0 2 2 2 0 AAA domain HET PF06985.11 OAG16649.1 - 1.6e-30 106.4 0.5 3.3e-30 105.3 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pirin PF02678.16 OAG16652.1 - 8.9e-28 96.4 0.1 2.1e-27 95.2 0.1 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OAG16652.1 - 1e-27 96.5 0.0 5.5e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAG16652.1 - 3.3e-08 33.1 0.1 0.00037 20.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG16652.1 - 0.0011 18.6 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) HET PF06985.11 OAG16654.1 - 2.4e-23 83.1 1.7 3.7e-23 82.5 1.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 OAG16655.1 - 1.7e-74 251.4 22.9 1.9e-74 251.2 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16655.1 - 9.5e-07 28.1 38.1 3e-05 23.1 13.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 OAG16656.1 - 2.2e-17 63.3 0.2 2.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain CD45 PF12567.8 OAG16657.1 - 0.012 15.6 1.9 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 Leukocyte receptor CD45 PPR_2 PF13041.6 OAG16658.1 - 1.2e-08 35.0 0.1 0.46 10.7 0.1 6.9 8 0 0 8 8 8 1 PPR repeat family PPR_3 PF13812.6 OAG16658.1 - 1.3e-05 25.1 0.0 3.5 7.8 0.0 4.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 OAG16658.1 - 2.5e-05 24.2 1.1 8.1 6.9 0.0 6.7 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 OAG16658.1 - 0.0004 19.8 0.0 0.97 8.7 0.0 3.9 4 0 0 4 4 4 1 Pentacotripeptide-repeat region of PRORP TPR_15 PF13429.6 OAG16658.1 - 0.026 13.7 1.7 3.9 6.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat YcaO_C PF18381.1 OAG16658.1 - 0.029 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain ENT PF03735.14 OAG16658.1 - 0.07 13.2 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 ENT domain DUF2520 PF10728.9 OAG16658.1 - 0.095 12.5 0.0 0.86 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) ANAPC3 PF12895.7 OAG16658.1 - 0.12 12.6 0.9 0.54 10.5 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ERAP1_C PF11838.8 OAG16658.1 - 0.6 9.6 6.1 6.6 6.2 0.1 3.7 3 1 1 4 4 4 0 ERAP1-like C-terminal domain TPR_14 PF13428.6 OAG16658.1 - 2.3 9.3 9.9 1.1e+02 4.0 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 OAG16659.1 - 3e-15 56.2 0.1 3e-15 56.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 QWRF PF04484.12 OAG16659.1 - 0.28 10.9 1.8 0.39 10.4 1.8 1.2 1 0 0 1 1 1 0 QWRF family Cellulase PF00150.18 OAG16660.1 - 3.2e-09 36.7 5.2 2.7e-08 33.6 5.2 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MPLKIP PF15502.6 OAG16661.1 - 2.3e-05 24.5 0.1 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein SNRNP27 PF08648.12 OAG16661.1 - 0.0034 17.4 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Homeobox_KN PF05920.11 OAG16662.1 - 8.4e-14 51.2 0.5 8.4e-14 51.2 0.5 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OAG16662.1 - 1e-06 28.5 0.1 3.8e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 OAG16662.1 - 0.0002 21.3 0.2 0.03 14.4 0.0 3.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAG16662.1 - 0.00032 21.3 1.8 0.00032 21.3 1.8 4.9 4 1 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG16662.1 - 0.00035 20.9 21.8 0.0014 19.0 1.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG16662.1 - 2.2 8.7 5.4 0.5 10.7 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.7 OAG16663.1 - 1.5e-47 160.1 0.3 5.3e-12 46.2 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG16663.1 - 8e-33 112.4 1.0 7.3e-05 23.2 0.0 9.4 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG16663.1 - 1.3e-24 83.6 0.1 0.00062 20.0 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OAG16663.1 - 6.7e-24 83.7 4.2 0.024 15.0 0.0 7.8 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OAG16663.1 - 9.5e-23 79.6 0.9 0.0026 18.2 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat zf-tcix PF14952.6 OAG16663.1 - 0.08 12.6 0.9 0.16 11.6 0.9 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Evr1_Alr PF04777.13 OAG16663.1 - 0.085 13.3 0.0 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Erv1 / Alr family HET PF06985.11 OAG16664.1 - 1.8e-07 31.6 0.2 3.5e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 OAG16667.1 - 1.3e-133 446.2 23.1 1.5e-133 446.0 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG16667.1 - 1.4e-24 86.7 56.4 1.3e-20 73.6 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arteri_Gl PF00951.18 OAG16667.1 - 0.0033 17.3 2.8 0.0033 17.3 2.8 2.1 2 0 0 2 2 2 1 Arterivirus GL envelope glycoprotein Chitin_bind_1 PF00187.19 OAG16668.1 - 5.5e-11 42.8 45.8 2.1e-07 31.3 21.4 4.8 5 0 0 5 5 5 2 Chitin recognition protein PAN_3 PF08277.12 OAG16668.1 - 0.0024 17.7 1.0 0.0024 17.7 1.0 4.1 4 0 0 4 4 4 2 PAN-like domain PAN_4 PF14295.6 OAG16668.1 - 0.004 17.0 0.3 0.004 17.0 0.3 5.3 5 0 0 5 5 5 2 PAN domain PAN_2 PF08276.11 OAG16668.1 - 0.017 15.2 3.4 0.017 15.2 3.4 4.0 3 1 1 4 4 4 0 PAN-like domain SPX PF03105.19 OAG16668.1 - 3.3 7.6 6.6 4.8 7.0 6.6 1.2 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 OAG16672.1 - 6.1e-59 196.0 8.3 1.2e-20 73.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Optomotor-blind PF11078.8 OAG16673.1 - 0.00028 21.4 0.2 0.0009 19.8 0.2 1.9 1 0 0 1 1 1 1 Optomotor-blind protein N-terminal region Glyco_hydro_18 PF00704.28 OAG16675.1 - 1.4e-64 218.8 0.0 2e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG16675.1 - 2.9e-10 40.4 7.4 2.9e-10 40.4 7.4 4.6 5 1 0 5 5 5 1 Chitin recognition protein Pectate_lyase_3 PF12708.7 OAG16676.1 - 2.9e-95 318.2 9.2 2.8e-81 272.5 4.9 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 OAG16676.1 - 3.2e-15 55.9 0.0 7.9e-07 29.0 0.0 3.4 3 0 0 3 3 3 2 LysM domain End_N_terminal PF12218.8 OAG16676.1 - 4.2e-05 23.1 3.7 0.033 13.9 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Kelch_5 PF13854.6 OAG16677.1 - 2.3e-14 53.0 3.6 2.7e-05 24.0 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 OAG16677.1 - 9.4e-06 25.5 10.0 0.46 10.5 0.2 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG16677.1 - 0.0012 18.7 1.2 0.22 11.6 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 OAG16677.1 - 0.0021 18.3 18.7 0.91 9.9 0.6 5.6 3 2 2 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OAG16677.1 - 0.016 15.5 17.5 0.54 10.6 0.2 5.4 6 0 0 6 6 6 0 Galactose oxidase, central domain SKG6 PF08693.10 OAG16677.1 - 0.051 13.0 1.1 0.093 12.2 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.25 OAG16677.1 - 0.16 11.6 8.4 1.2 8.8 0.1 3.8 4 0 0 4 4 4 0 Kelch motif Tmemb_14 PF03647.13 OAG16677.1 - 0.32 11.7 1.7 19 6.0 0.3 2.7 2 0 0 2 2 2 0 Transmembrane proteins 14C Myb_DNA-binding PF00249.31 OAG16679.1 - 5.9e-21 74.4 7.8 2.2e-12 46.9 0.2 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG16679.1 - 3.2e-15 56.1 10.2 1.4e-11 44.4 2.4 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAG16679.1 - 0.0032 17.8 0.5 0.0032 17.8 0.5 3.6 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OAG16679.1 - 0.1 12.7 0.7 0.45 10.6 0.7 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NAD_binding_4 PF07993.12 OAG16680.1 - 1.5e-42 145.6 0.0 2.2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG16680.1 - 1.8e-39 135.6 0.0 2.6e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG16680.1 - 3.9e-11 42.9 0.0 7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG16680.1 - 0.0002 21.6 0.0 0.00071 19.9 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAG16680.1 - 0.0018 17.3 0.0 0.004 16.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAG16680.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.2 3 0 0 3 3 3 0 KR domain NAD_binding_10 PF13460.6 OAG16680.1 - 0.087 12.7 0.3 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding MFS_1 PF07690.16 OAG16681.1 - 1.2e-36 126.4 19.9 1.2e-36 126.4 19.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG16681.1 - 4.6e-10 38.9 15.5 1.4e-09 37.4 15.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Bac_rhamnosid_C PF17390.2 OAG16683.1 - 2e-12 46.7 0.1 5.1e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 OAG16683.1 - 1.4e-06 27.8 0.0 1.1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 OAG16683.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 OAG16683.1 - 0.0069 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Cu_amine_oxid PF01179.20 OAG16685.1 - 3.3e-163 543.4 0.0 4.6e-163 542.9 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG16685.1 - 3e-06 27.4 0.0 6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG16685.1 - 0.00018 21.8 0.0 0.00046 20.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Acetyltransf_3 PF13302.7 OAG16686.1 - 2.1e-18 67.3 0.5 5.9e-18 65.9 0.5 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG16686.1 - 2e-09 37.7 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAG16686.1 - 3.9e-05 23.4 0.2 8.4e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG16686.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG16686.1 - 0.0019 18.1 0.1 0.0044 17.0 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein COesterase PF00135.28 OAG16687.1 - 1.2e-64 219.0 0.0 1.7e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG16687.1 - 4.6e-10 39.7 0.0 1.3e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG16687.1 - 0.02 13.8 0.1 0.06 12.2 0.1 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase Glyco_tranf_2_3 PF13641.6 OAG16688.1 - 1.7e-05 24.8 0.0 6.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG16688.1 - 2.7e-05 24.2 0.7 3.7e-05 23.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG16688.1 - 3.3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG16688.1 - 0.0066 15.9 0.2 0.084 12.3 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Peptidase_M3_N PF08439.10 OAG16688.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F GDP_Man_Dehyd PF16363.5 OAG16689.1 - 4.5e-37 128.2 0.0 3.3e-36 125.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG16689.1 - 3.6e-36 124.8 0.0 6.1e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG16689.1 - 3.6e-09 36.2 0.0 5.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OAG16689.1 - 3.9e-07 29.5 0.0 4.4e-06 26.0 0.0 2.4 2 2 1 4 4 4 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG16689.1 - 3.1e-06 26.4 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAG16689.1 - 6e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG16689.1 - 0.0053 16.2 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG16689.1 - 0.038 13.6 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAG16689.1 - 0.044 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG16689.1 - 0.054 13.4 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.21 OAG16690.1 - 5.3e-06 26.0 3.0 8.3e-06 25.4 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ank_4 PF13637.6 OAG16691.1 - 5.9e-16 58.6 0.4 4e-08 33.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG16691.1 - 7e-16 58.6 0.4 1.3e-15 57.7 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG16691.1 - 9.6e-16 56.3 0.3 0.00024 21.3 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OAG16691.1 - 8.4e-15 54.5 3.1 0.00052 20.3 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAG16691.1 - 2.8e-14 53.0 1.0 2e-06 28.0 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AMNp_N PF10423.9 OAG16691.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Ank_2 PF12796.7 OAG16692.1 - 1.1e-19 70.7 0.3 2.7e-08 34.3 0.0 5.1 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG16692.1 - 2.8e-16 59.6 0.2 7.2e-05 23.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG16692.1 - 2.6e-15 55.0 0.5 0.011 16.2 0.0 7.5 7 0 0 7 7 6 2 Ankyrin repeat Ank_5 PF13857.6 OAG16692.1 - 2.1e-14 53.4 0.3 1e-06 28.9 0.0 4.7 5 0 0 5 5 4 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG16692.1 - 6.4e-09 35.5 0.9 6.4e-09 35.5 0.9 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 OAG16692.1 - 9.8e-08 32.1 0.3 0.25 11.9 0.0 5.8 7 0 0 7 7 6 2 Ankyrin repeat NACHT PF05729.12 OAG16692.1 - 2.1e-05 24.5 0.1 5.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG16692.1 - 0.00013 22.4 0.1 0.00054 20.4 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG16692.1 - 0.0018 18.5 0.1 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAG16692.1 - 0.0061 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA PF00004.29 OAG16692.1 - 0.049 14.1 0.0 0.23 11.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF465 PF04325.13 OAG16692.1 - 0.067 13.2 1.8 0.2 11.7 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Spectrin PF00435.21 OAG16692.1 - 0.93 10.0 3.3 1.4 9.4 0.3 2.9 3 0 0 3 3 3 0 Spectrin repeat NPV_P10 PF05531.12 OAG16692.1 - 2.2 8.8 3.9 5.1 7.6 0.7 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein HET PF06985.11 OAG16693.1 - 9.7e-31 107.1 2.7 1.7e-30 106.3 1.5 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_6 PF14599.6 OAG16693.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon Hyd_WA PF06462.12 OAG16693.1 - 0.12 12.4 0.3 0.86 9.7 0.0 2.5 2 0 0 2 2 2 0 Propeller MFS_1 PF07690.16 OAG16694.1 - 6.2e-39 133.9 44.7 6.2e-39 133.9 44.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 OAG16695.1 - 6.1e-19 69.1 1.1 1e-18 68.3 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG16695.1 - 1.9e-05 24.7 0.2 3.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PQ-loop PF04193.14 OAG16697.1 - 1.5e-21 75.9 7.7 4.7e-19 67.9 2.2 3.1 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 OAG16697.1 - 0.13 12.3 2.1 0.41 10.7 0.1 2.7 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange ABC2_membrane_5 PF13346.6 OAG16697.1 - 0.15 11.6 9.5 1.5 8.3 6.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Herpes_pp85 PF04637.12 OAG16697.1 - 8.4 4.7 5.3 12 4.2 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Septin PF00735.18 OAG16698.1 - 6.3e-109 363.6 0.1 1.4e-108 362.5 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG16698.1 - 3e-06 27.3 0.0 7.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG16698.1 - 0.00014 22.0 4.4 0.12 12.5 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAG16698.1 - 0.0068 16.3 0.6 0.0068 16.3 0.6 2.6 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OAG16698.1 - 0.011 15.3 0.4 0.34 10.4 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain IIGP PF05049.13 OAG16698.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 OAG16698.1 - 0.049 12.9 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 OAG16698.1 - 0.1 12.9 1.8 0.19 12.0 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG16698.1 - 0.41 11.1 6.0 9.1 6.7 4.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_S17e PF00833.18 OAG16698.1 - 1.8 8.5 5.8 3.6 7.5 5.8 1.5 1 0 0 1 1 1 0 Ribosomal S17 WD40 PF00400.32 OAG16699.1 - 4.9e-06 27.2 0.9 0.025 15.5 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG16699.1 - 4e-05 23.8 0.0 0.00073 19.8 0.0 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG16699.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 OAG16699.1 - 0.052 12.9 0.0 0.17 11.2 0.0 1.7 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CPSF_A PF03178.15 OAG16699.1 - 0.14 11.4 0.0 11 5.3 0.0 2.1 1 1 1 2 2 2 0 CPSF A subunit region SH3_1 PF00018.28 OAG16700.1 - 1.3e-09 37.5 0.1 2.3e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG16700.1 - 1.9e-07 30.8 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG16700.1 - 1.5e-06 27.8 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.9 OAG16700.1 - 0.24 11.6 5.6 0.32 11.2 2.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) Dynactin_p22 PF07426.11 OAG16701.1 - 1.6e-10 41.1 0.4 2.5e-10 40.4 0.4 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Paf1 PF03985.13 OAG16701.1 - 0.12 11.4 6.9 0.17 10.9 6.9 1.3 1 0 0 1 1 1 0 Paf1 DUF809 PF05663.11 OAG16701.1 - 6.2 7.0 7.2 9.9 6.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Aa_trans PF01490.18 OAG16702.1 - 2.8e-91 306.3 15.7 4.2e-91 305.7 15.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2417 PF10329.9 OAG16702.1 - 3.2 7.1 9.7 3.9 6.8 0.2 3.4 3 1 0 3 3 3 0 Region of unknown function (DUF2417) HET PF06985.11 OAG16703.1 - 3e-30 105.5 0.1 6.7e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_S16 PF00886.19 OAG16704.1 - 1.1e-24 86.2 0.1 1.8e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 OAG16705.1 - 1e-33 116.7 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 OAG16705.1 - 0.0083 16.2 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized Strongylid L4 protein Borrelia_orfA PF02414.15 OAG16705.1 - 0.21 11.2 0.3 0.28 10.8 0.3 1.1 1 0 0 1 1 1 0 Borrelia ORF-A Carboxyl_trans PF01039.22 OAG16706.1 - 8.8e-138 460.0 0.4 1.3e-137 459.5 0.4 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Glyco_hydro_76 PF03663.14 OAG16706.1 - 5.2e-130 434.2 5.7 6.6e-130 433.9 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG16706.1 - 5.3 6.0 12.7 0.54 9.3 0.7 2.9 1 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 PAH PF02671.21 OAG16708.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat GLE1 PF07817.13 OAG16709.1 - 0.041 13.1 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 GLE1-like protein Bac_DnaA PF00308.18 OAG16709.1 - 0.13 12.1 0.3 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial dnaA protein Peptidase_S8 PF00082.22 OAG16712.1 - 1.9e-43 148.9 0.0 4e-43 147.8 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF3632 PF12311.8 OAG16714.1 - 1.1e-37 130.1 2.9 1.4e-37 129.8 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fip1 PF05182.13 OAG16714.1 - 0.047 13.2 0.6 0.1 12.1 0.6 1.6 1 0 0 1 1 1 0 Fip1 motif Hydrophobin_2 PF06766.11 OAG16715.1 - 0.066 13.2 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 Fungal hydrophobin Hydrophobin PF01185.18 OAG16716.1 - 2e-11 44.3 10.5 2.8e-11 43.9 10.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin zf-C2H2 PF00096.26 OAG16719.1 - 1e-08 35.1 8.7 8.7e-05 22.8 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG16719.1 - 0.0002 21.9 6.1 0.086 13.7 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG16719.1 - 0.0042 17.5 0.6 0.0042 17.5 0.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 OAG16719.1 - 0.017 15.5 2.3 0.23 11.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Bax1-I PF01027.20 OAG16720.1 - 1.8e-54 184.7 27.7 2e-54 184.5 27.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 OAG16720.1 - 0.14 11.9 0.2 0.6 9.8 0.2 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL FUSC_2 PF13515.6 OAG16720.1 - 1.4 9.1 18.6 3.7 7.7 16.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein-like TRAM_LAG1_CLN8 PF03798.16 OAG16721.1 - 2.8e-47 161.1 22.3 2.8e-47 161.1 22.3 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAG16721.1 - 6.9e-19 67.3 0.0 6.9e-19 67.3 0.0 2.2 2 0 0 2 2 2 1 TRAM1-like protein Y_phosphatase3 PF13350.6 OAG16722.1 - 3.8e-47 161.2 0.0 6.2e-47 160.5 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF2576 PF10845.8 OAG16722.1 - 0.14 11.8 0.3 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Y_phosphatase2 PF03162.13 OAG16722.1 - 0.26 10.8 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Bac_luciferase PF00296.20 OAG16723.1 - 9.3e-67 225.7 0.1 1.2e-66 225.3 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Gpr1_Fun34_YaaH PF01184.19 OAG16724.1 - 1.5e-32 112.9 13.3 1.7e-32 112.7 13.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC2_membrane_3 PF12698.7 OAG16724.1 - 8 5.5 13.2 9.6 5.2 13.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Acyl-CoA_dh_2 PF08028.11 OAG16725.1 - 5e-13 49.5 0.9 8.7e-13 48.7 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG16725.1 - 3.5e-05 24.4 0.0 6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG16725.1 - 0.00026 21.2 0.4 0.0049 17.1 0.1 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG16725.1 - 0.00026 21.1 0.1 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cellulase PF00150.18 OAG16726.1 - 6.8e-09 35.6 1.9 2.7e-08 33.6 1.9 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Bac_rhamnosid_C PF17390.2 OAG16727.1 - 4.9e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 OAG16727.1 - 0.00014 21.2 0.0 0.00034 20.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain FAD_binding_4 PF01565.23 OAG16729.1 - 5.9e-20 71.4 2.2 5.9e-20 71.4 2.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG16729.1 - 2.8e-11 43.3 0.2 6.2e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 OAG16730.1 - 3.2e-08 33.3 0.0 8.7e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16730.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG16730.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 KR domain p450 PF00067.22 OAG16731.1 - 4.6e-57 193.8 0.0 7.1e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 OAG16732.1 - 3.3e-08 33.6 0.1 6.4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG16732.1 - 4.7e-05 23.2 0.1 0.0048 16.8 0.2 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG16732.1 - 0.00033 21.7 0.0 0.00054 21.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RELT PF12606.8 OAG16732.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 p450 PF00067.22 OAG16733.1 - 7.8e-66 222.7 0.0 8.8e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 OAG16734.1 - 5.2e-64 216.3 0.1 4.8e-63 213.1 0.1 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG16734.1 - 1.5e-45 155.3 0.0 9.9e-44 149.4 0.0 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 OAG16734.1 - 2.7e-40 138.8 0.2 5.1e-40 137.9 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG16734.1 - 8.5e-40 136.8 0.0 1.8e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 OAG16734.1 - 4.7e-31 107.9 0.0 1.7e-30 106.1 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein Ketoacyl-synt_C PF02801.22 OAG16734.1 - 7.9e-31 106.5 0.1 2.4e-30 104.9 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG16734.1 - 5.6e-19 68.7 0.0 1.7e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16734.1 - 8.8e-15 55.2 0.0 1e-11 45.4 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG16734.1 - 4.3e-14 52.9 0.0 1.2e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 OAG16734.1 - 8.3e-13 48.4 0.0 7.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 OAG16734.1 - 1.4e-12 47.8 0.0 3.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG16734.1 - 8e-12 45.7 0.0 6.4e-10 39.6 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 OAG16734.1 - 1e-11 44.7 0.0 2.7e-10 40.0 0.0 3.1 4 0 0 4 4 4 1 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG16734.1 - 1.5e-07 30.7 0.0 1.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 OAG16734.1 - 2.7e-07 30.5 0.0 7.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 OAG16734.1 - 4.9e-05 22.8 0.1 0.00011 21.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 OAG16734.1 - 5.9e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 OAG16734.1 - 0.0035 16.9 0.1 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 OAG16734.1 - 0.007 16.2 0.2 0.024 14.5 0.2 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NNMT_PNMT_TEMT PF01234.17 OAG16734.1 - 0.032 13.4 0.1 0.31 10.2 0.0 2.4 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family PP-binding PF00550.25 OAG16734.1 - 0.12 12.7 0.1 0.39 11.1 0.1 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site AAA PF00004.29 OAG16735.1 - 2.6e-19 69.9 0.0 1.2e-18 67.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG16735.1 - 8.2e-06 26.1 0.1 7.9e-05 23.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG16735.1 - 9.4e-06 25.7 0.0 3.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG16735.1 - 0.00013 22.4 0.2 0.00063 20.2 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OAG16735.1 - 0.0043 17.2 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) MCM_lid PF17855.1 OAG16735.1 - 0.0075 16.7 0.8 0.017 15.5 0.1 2.0 2 0 0 2 2 1 1 MCM AAA-lid domain AAA_11 PF13086.6 OAG16735.1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG16735.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAG16735.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG16735.1 - 0.065 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG16735.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG16735.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF346 PF03984.13 OAG16736.1 - 0.043 13.6 0.5 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) DUF2207 PF09972.9 OAG16736.1 - 0.052 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_6 PF12697.7 OAG16738.1 - 4.2e-16 60.2 0.0 5.6e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG16738.1 - 2.3e-11 43.8 0.4 4.2e-11 43.0 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG16738.1 - 2.8e-07 30.1 0.0 5.9e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 OAG16738.1 - 0.22 10.5 0.1 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Herpes_gE PF02480.16 OAG16743.1 - 0.0024 16.7 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 OAG16743.1 - 0.003 16.9 1.0 0.0054 16.1 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG16743.1 - 0.0033 18.3 0.0 0.0052 17.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.8 OAG16743.1 - 0.0082 16.4 0.3 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF5385 PF17359.2 OAG16743.1 - 0.015 14.8 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Adeno_E3_CR2 PF02439.15 OAG16743.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 YajC PF02699.15 OAG16743.1 - 0.05 13.5 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit BOP1NT PF08145.12 OAG16743.1 - 0.051 13.5 0.3 0.073 13.0 0.3 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain BatA PF07584.11 OAG16743.1 - 0.056 13.8 0.0 0.097 13.1 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal PTP_tm PF18861.1 OAG16743.1 - 0.059 13.4 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD34_antigen PF06365.12 OAG16743.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4381 PF14316.6 OAG16743.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FeoB_associated PF12669.7 OAG16743.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.4 3 0 0 3 3 2 0 FeoB-associated Cys-rich membrane protein Pkinase PF00069.25 OAG16744.1 - 2e-15 56.9 0.0 3.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16744.1 - 7.1e-09 35.3 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG16744.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Ank_2 PF12796.7 OAG16744.1 - 0.022 15.4 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Pox_ser-thr_kin PF05445.11 OAG16744.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ank_3 PF13606.6 OAG16744.1 - 0.17 12.5 0.0 1.1 10.1 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat AAA_35 PF14516.6 OAG16745.1 - 0.062 12.1 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain zf-met PF12874.7 OAG16745.1 - 0.064 13.7 1.2 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sugar_tr PF00083.24 OAG16746.1 - 5.1e-60 203.6 13.9 9e-31 107.2 4.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG16746.1 - 1.3e-17 63.8 31.4 1.8e-10 40.3 10.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG16746.1 - 0.0043 15.5 2.4 0.0043 15.5 2.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NTPase_P4 PF11602.8 OAG16746.1 - 0.19 10.9 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 p450 PF00067.22 OAG16747.1 - 4.3e-38 131.3 0.0 5.2e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-DNL PF05180.12 OAG16748.1 - 4.7e-31 106.5 1.0 6.3e-31 106.1 1.0 1.2 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.19 OAG16748.1 - 0.014 15.4 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 OAG16748.1 - 0.082 12.8 0.3 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 OAG16748.1 - 0.98 9.4 5.6 13 5.8 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cullin PF00888.22 OAG16749.1 - 1.3e-205 684.7 7.1 1.5e-205 684.5 7.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG16749.1 - 2.1e-26 91.7 1.9 3e-25 88.0 0.1 3.4 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_IclR PF09339.10 OAG16749.1 - 0.12 12.2 0.1 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain Sas10_Utp3 PF04000.15 OAG16750.1 - 4e-20 72.2 2.3 4e-20 72.2 2.3 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CCDC106 PF15794.5 OAG16750.1 - 0.67 9.6 10.5 0.12 12.1 4.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Asp-B-Hydro_N PF05279.11 OAG16750.1 - 2.8 7.9 11.8 0.5 10.4 4.9 2.0 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region HET PF06985.11 OAG16751.1 - 1.2e-17 64.6 0.0 1.5e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 OAG16752.1 - 7.7e-09 35.5 8.4 7.7e-09 35.5 8.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_E_B PF04042.16 OAG16753.1 - 0.15 11.4 0.6 0.53 9.6 0.3 1.8 1 1 1 2 2 2 0 DNA polymerase alpha/epsilon subunit B TP_methylase PF00590.20 OAG16754.1 - 8.9e-24 84.6 0.6 1.8e-23 83.6 0.6 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 OAG16755.1 - 3e-23 81.7 0.0 1.3e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 OAG16755.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Ribosomal_L19e PF01280.20 OAG16756.1 - 1.8e-61 206.4 7.6 1.8e-61 206.4 7.6 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 OAG16756.1 - 0.32 10.5 4.1 0.43 10.1 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) HTH_17 PF12728.7 OAG16756.1 - 0.35 11.1 4.1 0.55 10.5 0.2 2.9 3 1 0 3 3 3 0 Helix-turn-helix domain FUSC PF04632.12 OAG16757.1 - 5.9 5.3 8.5 10 4.5 8.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 OAG16757.1 - 7 6.8 49.8 9 6.5 2.5 4.3 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Taxilin PF09728.9 OAG16757.1 - 9 5.4 41.4 0.71 9.0 25.4 2.6 3 0 0 3 3 3 0 Myosin-like coiled-coil protein F-box PF00646.33 OAG16759.1 - 0.13 12.2 1.9 0.2 11.6 0.2 2.3 2 0 0 2 2 2 0 F-box domain SUZ PF12752.7 OAG16760.1 - 0.67 10.8 0.1 0.67 10.8 0.1 2.6 2 1 0 2 2 2 0 SUZ domain EF_TS PF00889.19 OAG16761.1 - 0.033 13.8 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor TS Band_7 PF01145.25 OAG16763.1 - 5.3e-15 55.9 0.5 5.3e-15 55.9 0.5 3.2 1 1 2 3 3 3 1 SPFH domain / Band 7 family NIF3 PF01784.18 OAG16765.1 - 2.6e-60 204.1 0.0 3.5e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 OAG16766.1 - 2.1e-16 59.9 0.0 5.6e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein COG6 PF06419.11 OAG16767.1 - 6.5e-218 725.0 10.1 7.4e-218 724.8 10.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 HsbA PF12296.8 OAG16767.1 - 0.022 15.2 0.8 0.092 13.2 0.4 2.4 2 0 0 2 2 2 0 Hydrophobic surface binding protein A COG2 PF06148.11 OAG16767.1 - 0.056 13.5 2.2 0.18 11.9 0.3 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.6 OAG16767.1 - 0.1 13.0 9.1 2 8.7 1.0 4.2 3 1 1 4 4 4 0 Organelle biogenesis, Muted-like protein C166 PF17615.2 OAG16767.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function AAA_24 PF13479.6 OAG16767.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain APG9 PF04109.16 OAG16768.1 - 2.3e-182 607.3 7.9 2.7e-182 607.1 7.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2721 PF11026.8 OAG16768.1 - 6.6 6.6 7.3 11 6.0 3.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Ribosomal_L16 PF00252.18 OAG16769.1 - 2.9e-44 150.3 0.0 4e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 OAG16770.1 - 6.8e-25 86.6 0.0 7.7e-25 86.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MCM PF00493.23 OAG16771.1 - 4.1e-103 343.3 0.0 6.2e-103 342.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG16771.1 - 3.2e-39 133.7 0.0 5.6e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAG16771.1 - 1.7e-27 96.6 31.4 1.7e-27 96.6 31.4 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAG16771.1 - 5.1e-24 84.5 2.4 6.9e-24 84.1 0.9 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAG16771.1 - 2.6e-16 60.1 0.1 7.8e-16 58.6 0.1 1.8 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG16771.1 - 1.8e-08 34.0 0.0 2e-06 27.4 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG16771.1 - 2.9e-06 27.3 0.0 6.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG16771.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG16771.1 - 0.0027 17.4 0.1 0.018 14.7 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF3113 PF11310.8 OAG16771.1 - 0.047 13.7 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) FAM92 PF06730.11 OAG16771.1 - 0.051 13.0 0.8 0.11 11.9 0.8 1.5 1 0 0 1 1 1 0 FAM92 protein AAA_30 PF13604.6 OAG16771.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain zf-UBR PF02207.20 OAG16772.1 - 1.4e-13 50.8 5.1 1.4e-13 50.8 5.1 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) API5 PF05918.11 OAG16772.1 - 0.13 11.1 1.4 0.27 10.0 1.4 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Kinesin PF00225.23 OAG16773.1 - 1.6e-83 280.4 0.5 2.3e-83 279.9 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG16773.1 - 2.2e-19 69.9 0.0 4.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 OAG16773.1 - 0.00022 20.9 0.0 0.057 13.3 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG16773.1 - 0.00032 21.3 2.8 0.079 13.6 0.1 2.8 2 1 1 3 3 3 2 Helix-hairpin-helix domain Trimer_CC PF08954.11 OAG16773.1 - 0.014 14.9 0.1 0.069 12.7 0.1 2.3 1 0 0 1 1 1 0 Trimerisation motif COQ7 PF03232.13 OAG16773.1 - 0.04 13.7 0.6 0.24 11.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 FAD_SOX PF18371.1 OAG16773.1 - 0.062 13.7 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase AAA_22 PF13401.6 OAG16773.1 - 0.49 10.7 2.5 0.68 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran_CTD PF16326.5 OAG16773.1 - 3.5 7.9 6.4 5.5 7.3 2.2 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain XFP_N PF09364.10 OAG16774.1 - 3.1e-170 565.8 0.0 4.2e-170 565.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 OAG16774.1 - 7.4e-84 280.2 0.0 1.2e-83 279.5 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAG16774.1 - 1.9e-82 275.2 0.0 3.1e-82 274.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase FA_desaturase PF00487.24 OAG16775.1 - 2.3e-23 83.3 27.8 3.7e-23 82.7 27.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG16775.1 - 1.4e-10 41.2 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGM_PMM_I PF02878.16 OAG16776.1 - 2.9e-40 137.2 0.0 5.6e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OAG16776.1 - 6.4e-24 84.5 0.1 3.7e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAG16776.1 - 4.2e-14 52.7 0.0 8.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OAG16776.1 - 5.3e-09 36.1 0.0 5.7e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SCAN PF02023.17 OAG16776.1 - 0.14 12.0 0.2 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 SCAN domain Homeodomain PF00046.29 OAG16776.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain COR PF16095.5 OAG16779.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain Telethonin PF09470.10 OAG16779.1 - 0.23 11.3 0.0 0.31 10.9 0.0 1.1 1 0 0 1 1 1 0 Telethonin protein PQ-loop PF04193.14 OAG16781.1 - 5.8e-23 80.4 7.2 2.1e-17 62.7 0.2 3.3 3 1 1 4 4 4 2 PQ loop repeat Peptidase_U4 PF03419.13 OAG16781.1 - 0.02 14.2 6.0 0.041 13.2 6.0 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Evr1_Alr PF04777.13 OAG16782.1 - 6.4e-30 103.6 3.2 1.1e-29 102.8 3.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family PspB PF06667.12 OAG16783.1 - 0.004 17.2 0.3 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Phage shock protein B Pkinase PF00069.25 OAG16784.1 - 4.4e-67 226.2 0.0 5.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16784.1 - 7.1e-32 110.7 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG16784.1 - 0.00024 20.5 0.3 0.00038 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG16784.1 - 0.0025 16.8 0.6 0.0041 16.1 0.2 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OAG16784.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG16784.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG16784.1 - 0.033 13.3 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.29 OAG16786.1 - 1.5e-48 164.9 0.0 3.9e-48 163.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG16786.1 - 9.5e-31 106.4 0.0 1.9e-28 99.0 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAG16786.1 - 3.5e-05 22.8 0.0 0.00046 19.1 0.0 2.3 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAG16786.1 - 9.2e-05 21.8 0.0 9.2e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OAG16786.1 - 0.12 11.7 0.0 0.12 11.7 0.0 3.2 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Macoilin PF09726.9 OAG16786.1 - 0.65 8.5 14.1 0.93 8.0 14.1 1.1 1 0 0 1 1 1 0 Macoilin family TFIIIC_delta PF12657.7 OAG16787.1 - 1.6e-42 145.6 0.7 1.8e-41 142.1 0.2 2.5 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAG16787.1 - 5.4e-33 113.0 0.0 1.4e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex BsuBI_PstI_RE PF06616.11 OAG16787.1 - 0.17 11.2 0.0 0.4 9.9 0.0 1.6 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Ctr PF04145.15 OAG16788.1 - 7.3e-42 143.5 1.6 8.5e-42 143.3 1.6 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF1180 PF06679.12 OAG16788.1 - 0.16 12.3 2.4 0.29 11.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PAP2 PF01569.21 OAG16788.1 - 0.21 11.4 4.9 0.53 10.0 4.3 1.8 1 1 1 2 2 2 0 PAP2 superfamily DUF2244 PF10003.9 OAG16788.1 - 9.8 5.8 6.8 11 5.7 4.0 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DJ-1_PfpI PF01965.24 OAG16789.1 - 5.3e-12 45.8 0.0 6.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 OAG16789.1 - 0.0037 17.1 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DIT1_PvcA PF05141.12 OAG16790.1 - 1.1e-89 300.6 0.0 1.5e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 OAG16791.1 - 1.4e-59 202.1 0.0 1.7e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG16792.1 - 3.5e-34 118.3 45.9 5.9e-34 117.5 36.5 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 OAG16792.1 - 0.083 11.2 3.7 0.28 9.4 3.5 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DSBA PF01323.20 OAG16793.1 - 1e-35 123.3 0.0 1.1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OAG16793.1 - 4.9e-05 23.6 1.2 0.00017 21.8 0.1 2.1 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 OAG16793.1 - 0.044 13.5 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 OAG16793.1 - 0.19 11.8 0.3 2.4 8.3 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin domain IDO PF01231.18 OAG16794.1 - 1.4e-09 37.3 0.4 7.9e-09 34.8 0.4 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase EBV-NA1 PF02905.14 OAG16794.1 - 0.063 13.1 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain FUSC_2 PF13515.6 OAG16795.1 - 1.4e-31 109.3 7.3 1.4e-31 109.3 7.3 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAG16795.1 - 1.5e-07 30.6 15.0 0.015 14.2 5.3 4.4 4 0 0 4 4 4 3 Aluminium activated malate transporter FUSC PF04632.12 OAG16795.1 - 1e-05 24.3 5.6 0.26 9.8 0.1 3.3 3 0 0 3 3 3 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 OAG16795.1 - 0.0005 20.0 0.2 0.0012 18.7 0.1 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 Phage_holin_Dp1 PF16938.5 OAG16795.1 - 1.3 9.3 4.1 0.5 10.6 0.1 2.4 3 0 0 3 3 3 0 Putative phage holin Dp-1 Catalase PF00199.19 OAG16796.1 - 2e-159 530.8 0.0 2.9e-159 530.3 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 OAG16796.1 - 8.6e-46 155.3 0.2 1.9e-45 154.2 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 OAG16796.1 - 1.4e-14 54.0 0.0 2.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Pil1 PF13805.6 OAG16797.1 - 4e-96 321.6 8.2 4.7e-96 321.3 8.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Sec23_trunk PF04811.15 OAG16798.1 - 2.2e-64 217.3 0.0 4.2e-64 216.4 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG16798.1 - 3e-23 81.6 0.0 8.4e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAG16798.1 - 2.3e-17 63.5 0.0 5.8e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAG16798.1 - 5.4e-17 61.5 4.3 1e-16 60.7 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG16798.1 - 2.7e-07 30.4 0.0 8.3e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG16798.1 - 0.011 15.1 0.5 0.052 12.9 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2 PF00096.26 OAG16799.1 - 1.5e-05 25.2 12.0 0.0045 17.4 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG16799.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG16799.1 - 0.0013 19.4 11.3 0.08 13.8 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OAG16799.1 - 1.5 8.7 5.6 2.6 7.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Mad3_BUB1_I PF08311.12 OAG16800.1 - 3.6e-45 152.9 0.5 3e-44 150.0 0.1 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OAG16800.1 - 4.1e-16 59.1 0.0 3.8e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 OAG16800.1 - 4.1e-09 36.5 0.0 3.3e-08 33.6 0.0 2.6 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 OAG16800.1 - 6.7e-07 28.8 0.0 2.1e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG16800.1 - 0.033 14.1 0.3 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG16800.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4629 PF15442.6 OAG16800.1 - 7.8 6.7 17.1 29 4.9 17.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) PCI PF01399.27 OAG16801.1 - 8.1e-06 26.3 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain FeoC PF09012.10 OAG16801.1 - 0.096 12.8 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator SURF6 PF04935.12 OAG16805.1 - 8.3e-45 153.0 49.5 8.3e-45 153.0 49.5 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 OAG16805.1 - 2.2e-17 63.4 0.9 2.2e-17 63.4 0.9 9.0 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 DUF3446 PF11928.8 OAG16805.1 - 0.11 12.8 4.9 0.24 11.7 4.9 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Fer4 PF00037.27 OAG16806.1 - 2.3e-14 52.5 15.3 2.1e-08 33.7 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAG16806.1 - 5.6e-13 49.3 9.8 8.4e-13 48.7 9.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAG16806.1 - 7.4e-11 42.8 7.6 2.9e-05 24.9 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAG16806.1 - 1.5e-10 41.0 31.8 6.8e-07 29.3 11.8 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG16806.1 - 4.4e-09 36.3 21.3 2.6e-06 27.5 12.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAG16806.1 - 1.8e-08 34.4 10.2 3e-08 33.7 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG16806.1 - 2.6e-07 31.0 19.0 0.00011 22.6 11.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OAG16806.1 - 9.9e-07 28.6 16.9 0.0004 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OAG16806.1 - 3.9e-06 26.6 12.1 0.0082 16.2 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAG16806.1 - 6.7e-06 26.2 10.8 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAG16806.1 - 0.00023 21.7 12.2 0.0056 17.2 12.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAG16806.1 - 0.011 16.6 15.7 0.018 15.9 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 OAG16806.1 - 0.028 15.0 15.1 0.75 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAG16806.1 - 0.029 14.6 5.1 1 9.6 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAG16806.1 - 0.076 13.2 8.9 2.8 8.1 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 OAG16806.1 - 0.095 12.8 5.3 0.47 10.6 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OAG16806.1 - 0.66 10.8 11.6 1.6 9.6 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain GPP34 PF05719.11 OAG16807.1 - 4.1e-68 229.4 0.1 6e-68 228.9 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 OAG16807.1 - 8.5e-10 38.9 0.1 1.6e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAG16807.1 - 6.4e-08 32.7 0.1 1.4e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-carrier SNF5 PF04855.12 OAG16808.1 - 5.8e-67 226.0 2.1 7.3e-66 222.3 2.1 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TFIIA_gamma_N PF02268.16 OAG16808.1 - 0.065 13.3 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain PHD PF00628.29 OAG16809.1 - 2.4e-13 49.7 22.4 1.2e-07 31.5 11.1 2.6 2 0 0 2 2 2 2 PHD-finger Peptidase_M24 PF00557.24 OAG16809.1 - 2.2e-06 27.5 0.1 4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Hydin_ADK PF17213.3 OAG16809.1 - 0.0025 18.1 5.3 0.0025 18.1 5.3 3.1 2 1 0 2 2 2 1 Hydin Adenylate kinase-like domain Exo_endo_phos PF03372.23 OAG16809.1 - 0.003 17.1 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C1_1 PF00130.22 OAG16809.1 - 0.12 12.3 18.2 0.078 12.9 5.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OAG16809.1 - 1.3 9.4 12.6 3.3 8.0 6.0 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAG16809.1 - 2.3 8.4 7.6 5.9 7.1 1.8 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain AP3D1 PF06375.11 OAG16809.1 - 2.9 8.1 14.1 0.14 12.4 6.4 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 tRNA-synt_2 PF00152.20 OAG16810.1 - 2e-85 286.6 0.2 5.8e-85 285.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG16810.1 - 6.2e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DOPA_dioxygen PF08883.11 OAG16811.1 - 8.5e-47 157.8 0.0 1e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family SRP14 PF02290.15 OAG16812.1 - 1.6e-29 102.1 0.4 4.1e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein AP3D1 PF06375.11 OAG16812.1 - 0.072 13.3 3.3 0.097 12.9 3.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Pyr_redox_2 PF07992.14 OAG16813.1 - 1.7e-67 227.7 7.3 3.1e-67 226.9 7.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG16813.1 - 3.2e-39 133.6 0.4 1.3e-38 131.6 0.1 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MA3 PF02847.17 OAG16813.1 - 3.9e-23 81.6 0.0 9.8e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Pyr_redox PF00070.27 OAG16813.1 - 5.8e-23 81.2 9.5 7e-20 71.4 1.9 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MIF4G PF02854.19 OAG16813.1 - 1.9e-22 80.0 0.9 6.6e-22 78.2 0.2 2.0 2 0 0 2 2 2 1 MIF4G domain NAD_binding_8 PF13450.6 OAG16813.1 - 6.2e-10 39.2 4.9 5e-06 26.7 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG16813.1 - 1.9e-08 33.8 11.3 3.4e-08 33.0 1.8 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG16813.1 - 2.8e-08 33.4 5.4 5.5e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG16813.1 - 2.9e-08 33.5 0.4 2.9e-08 33.5 0.4 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG16813.1 - 3.6e-07 29.7 6.6 0.003 16.9 0.6 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAG16813.1 - 3.3e-06 26.5 3.4 3.3e-06 26.5 3.4 2.7 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG16813.1 - 6.6e-05 22.6 15.7 0.005 16.5 0.7 3.9 4 0 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG16813.1 - 0.00037 19.7 1.7 0.42 9.7 0.1 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG16813.1 - 0.00039 19.3 2.8 0.00039 19.3 2.8 4.4 4 1 1 5 5 5 1 HI0933-like protein Thi4 PF01946.17 OAG16813.1 - 0.0011 18.3 0.1 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Spt5_N PF11942.8 OAG16813.1 - 0.0018 19.3 2.2 0.0018 19.3 2.2 5.4 4 1 1 5 5 3 1 Spt5 transcription elongation factor, acidic N-terminal Lycopene_cycl PF05834.12 OAG16813.1 - 0.0045 16.1 0.9 0.07 12.2 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAG16813.1 - 0.013 14.9 1.1 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG16813.1 - 0.019 15.4 4.6 1.1 9.8 0.2 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAG16813.1 - 0.037 13.3 13.2 0.27 10.4 1.4 3.3 2 1 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG16813.1 - 1.7 8.2 5.3 2.3 7.7 0.2 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OAG16813.1 - 2.2 8.2 12.2 0.074 12.9 2.4 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OAG16813.1 - 3.8 6.2 8.6 0.26 10.1 1.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Drc1-Sld2 PF11719.8 OAG16814.1 - 9.7e-89 299.0 11.2 9.7e-89 299.0 11.2 1.8 2 0 0 2 2 2 1 DNA replication and checkpoint protein CSN8_PSD8_EIF3K PF10075.9 OAG16814.1 - 7.1e-21 74.7 0.0 3e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAG16814.1 - 0.00019 20.9 0.0 0.00047 19.6 0.0 1.7 1 1 0 1 1 1 1 SAC3/GANP family Transpeptidase PF00905.22 OAG16814.1 - 0.088 12.0 0.5 0.15 11.3 0.5 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain ADH_zinc_N PF00107.26 OAG16815.1 - 2e-25 89.3 0.1 4.1e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG16815.1 - 1e-19 70.4 3.4 1e-19 70.4 3.4 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG16815.1 - 0.00013 21.3 0.2 0.00022 20.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG16815.1 - 0.00063 20.8 0.0 0.0012 19.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG16815.1 - 0.002 17.5 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAG16815.1 - 0.0032 17.7 0.1 0.0058 16.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 OAG16815.1 - 0.0055 17.4 0.6 0.012 16.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG16815.1 - 0.0084 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 OAG16815.1 - 0.014 15.3 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG16815.1 - 0.016 14.8 0.3 0.029 13.9 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 OAG16815.1 - 0.15 12.7 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 OAG16815.1 - 0.69 10.6 4.4 0.32 11.7 0.7 2.4 3 0 0 3 3 3 0 PglD N-terminal domain Glyco_hydro_15 PF00723.21 OAG16817.1 - 1.3e-53 182.4 0.0 4.1e-51 174.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 adh_short PF00106.25 OAG16818.1 - 6.2e-25 87.8 0.0 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16818.1 - 2.6e-16 59.9 0.0 5.9e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG16818.1 - 5.4e-07 29.7 0.1 9.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG16818.1 - 0.03 14.2 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG16818.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 OAG16818.1 - 0.046 12.9 0.3 0.068 12.4 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_4 PF13637.6 OAG16820.1 - 8.8e-06 26.2 0.4 2.8e-05 24.6 0.2 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG16820.1 - 1.6e-05 25.4 0.1 3.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG16820.1 - 1.8e-05 24.8 0.2 0.0039 17.6 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OAG16820.1 - 0.00017 21.8 0.9 0.002 18.5 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAG16820.1 - 0.0012 19.2 0.2 0.0036 17.6 0.2 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG16820.1 - 0.0042 16.5 0.3 0.0078 15.6 0.3 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF1940 PF09155.10 OAG16820.1 - 0.0079 16.3 0.5 0.049 13.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1940) Snapin_Pallidin PF14712.6 OAG16820.1 - 0.038 14.4 0.2 0.1 13.1 0.2 1.7 1 0 0 1 1 1 0 Snapin/Pallidin SesA PF17107.5 OAG16820.1 - 0.16 12.2 2.4 0.17 12.1 0.6 2.0 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sugar_tr PF00083.24 OAG16821.1 - 6.3e-77 259.3 13.5 1.1e-39 136.6 5.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG16821.1 - 2.9e-21 75.8 33.1 2.3e-11 43.2 19.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2206 PF09971.9 OAG16821.1 - 0.082 11.6 2.5 0.15 10.8 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) TPR_2 PF07719.17 OAG16821.1 - 0.12 12.6 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Inhibitor_I66 PF16850.5 OAG16822.1 - 7.5e-05 22.6 0.0 0.00025 20.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I66 Abhydrolase_6 PF12697.7 OAG16823.1 - 2e-13 51.5 0.9 3e-13 50.9 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG16823.1 - 6.6e-12 45.2 0.1 1.3e-11 44.2 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG16823.1 - 4.4e-08 33.3 0.0 5.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAG16823.1 - 5.8e-05 22.9 0.1 9.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAG16823.1 - 0.033 14.0 0.1 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 OAG16823.1 - 0.042 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GST_N PF02798.20 OAG16825.1 - 5.3e-12 45.9 0.0 8.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG16825.1 - 2.4e-09 37.3 0.0 3.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG16825.1 - 1.5e-07 31.7 0.0 5e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG16825.1 - 7.6e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG16825.1 - 6.4e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG16825.1 - 0.00017 21.5 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf_C2HC_14 PF18574.1 OAG16825.1 - 0.022 14.6 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 C2HC Zing finger domain PXA PF02194.15 OAG16826.1 - 5.8e-29 101.4 0.1 5.8e-29 101.4 0.1 2.3 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 OAG16826.1 - 3.8e-25 88.6 0.7 9.8e-25 87.3 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 OAG16826.1 - 1.5e-05 24.9 0.0 6.8e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 PX domain 4HBT PF03061.22 OAG16827.1 - 1.1e-11 45.0 0.0 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG16827.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) BTB PF00651.31 OAG16830.1 - 0.0019 18.4 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DP-EP PF08985.11 OAG16830.1 - 0.052 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 DP-EP family BTB PF00651.31 OAG16831.1 - 2.5e-05 24.5 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Catalase PF00199.19 OAG16832.1 - 7.1e-174 578.4 1.3 9e-174 578.0 1.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG16832.1 - 5.4e-16 58.6 0.0 1.4e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive PHD PF00628.29 OAG16833.1 - 1.1e-09 38.1 1.4 2.3e-09 37.0 1.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG16833.1 - 0.025 14.1 2.4 0.044 13.3 2.4 1.4 1 0 0 1 1 1 0 PHD-finger PNTB PF02233.16 OAG16835.1 - 8e-174 578.9 23.6 8e-174 578.9 23.6 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OAG16835.1 - 4.4e-73 245.1 0.1 1.2e-72 243.7 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OAG16835.1 - 4.5e-43 146.8 0.0 1.2e-42 145.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OAG16835.1 - 8.5e-31 106.3 1.5 8.5e-31 106.3 1.5 5.4 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OAG16835.1 - 0.0028 17.0 0.2 0.65 9.3 0.1 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 OAG16835.1 - 0.0039 16.9 0.2 0.02 14.6 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 OAG16835.1 - 0.05 12.8 1.9 0.062 12.5 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.14 OAG16835.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) GIDA PF01134.22 OAG16835.1 - 0.099 11.7 1.3 0.2 10.7 1.3 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M17_N PF02789.17 OAG16835.1 - 3.6 7.4 5.0 4.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain PAN_4 PF14295.6 OAG16836.1 - 0.088 12.7 3.4 0.076 12.9 0.8 2.4 2 0 0 2 2 2 0 PAN domain DUF4360 PF14273.6 OAG16838.1 - 3.7e-65 219.1 6.3 4.4e-65 218.9 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3586 PF12131.8 OAG16838.1 - 0.0095 16.1 2.1 0.023 14.9 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Velvet PF11754.8 OAG16839.1 - 0.0001 22.4 0.9 0.00026 21.0 0.9 1.9 1 1 0 1 1 1 1 Velvet factor tRNA-synt_1d PF00750.19 OAG16840.1 - 5.1e-98 328.2 9.6 1.9e-97 326.3 9.6 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG16840.1 - 3.8e-28 98.0 4.2 4.5e-28 97.8 0.3 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OAG16840.1 - 2.2e-05 25.0 0.0 2.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DivIC PF04977.15 OAG16840.1 - 0.3 10.9 5.2 0.91 9.3 3.4 2.4 2 0 0 2 2 2 0 Septum formation initiator RTA1 PF04479.13 OAG16843.1 - 2.5e-78 262.4 0.4 2.5e-78 262.4 0.4 1.6 1 1 1 2 2 2 1 RTA1 like protein BTB PF00651.31 OAG16844.1 - 0.055 13.7 0.0 0.56 10.4 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain DDOST_48kD PF03345.14 OAG16846.1 - 1.9e-155 517.8 0.0 2.2e-155 517.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GST_N_2 PF13409.6 OAG16847.1 - 5.7e-15 55.4 0.0 1.5e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG16847.1 - 1.3e-09 37.9 0.0 4.7e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG16847.1 - 0.0013 18.8 0.1 0.0045 17.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG16847.1 - 0.008 16.4 0.0 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG16847.1 - 0.027 14.9 0.0 7 7.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cation_efflux PF01545.21 OAG16848.1 - 2.4e-50 171.0 9.7 3.1e-50 170.7 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 OAG16848.1 - 7.3e-05 22.0 1.6 7.3e-05 22.0 1.6 2.2 2 1 1 3 3 3 1 Branched-chain amino acid transport system / permease component zf-met2 PF12907.7 OAG16849.1 - 1.6e-11 44.1 6.4 2.6e-11 43.5 6.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAG16849.1 - 0.017 16.0 11.2 0.093 13.6 11.2 2.0 1 1 0 1 1 1 0 4F5 protein family DUF3721 PF12518.8 OAG16849.1 - 0.036 13.9 0.4 0.074 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function Cys_rich_CPXG PF14255.6 OAG16851.1 - 0.0038 17.1 1.9 0.41 10.6 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich CPXCG BMF PF15185.6 OAG16851.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 Bcl-2-modifying factor, apoptosis zf-RING_2 PF13639.6 OAG16851.1 - 0.044 14.1 4.6 0.044 14.1 4.6 2.3 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_2 PF13240.6 OAG16851.1 - 0.065 13.0 0.5 0.18 11.6 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon domain F-box-like PF12937.7 OAG16854.1 - 4.1e-05 23.4 0.6 9.2e-05 22.3 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16854.1 - 0.00019 21.2 1.2 0.00042 20.1 1.2 1.6 1 0 0 1 1 1 1 F-box domain UL45 PF05473.12 OAG16854.1 - 0.026 14.2 0.3 0.036 13.7 0.3 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Oxidored_FMN PF00724.20 OAG16855.1 - 2.5e-44 152.0 0.0 3.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 OAG16855.1 - 0.00079 18.6 0.1 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-UBR PF02207.20 OAG16857.1 - 6e-19 68.0 13.2 6e-19 68.0 13.2 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAG16857.1 - 0.001 18.8 0.1 0.0027 17.4 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 OAG16857.1 - 0.016 15.5 0.8 0.016 15.5 0.8 4.0 4 1 0 4 4 4 0 Ring finger domain CAP_N PF01213.19 OAG16857.1 - 0.88 9.0 3.6 1.7 8.1 3.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.12 OAG16858.1 - 2.7e-23 81.6 0.4 3e-23 81.5 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 OAG16859.1 - 3.4e-16 58.8 2.7 7.5e-16 57.7 2.7 1.6 1 0 0 1 1 1 1 Mago binding Cu-oxidase PF00394.22 OAG16860.1 - 7.6e-33 113.9 0.1 7.9e-32 110.6 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG16860.1 - 9.7e-27 93.4 3.1 3.8e-26 91.4 0.0 3.1 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG16860.1 - 1.3e-24 86.5 5.7 1.2e-21 76.9 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase Big_2 PF02368.18 OAG16861.1 - 0.025 14.5 1.6 2.6 8.0 0.4 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) DUF3325 PF11804.8 OAG16861.1 - 0.12 12.5 0.1 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Methyltransf_11 PF08241.12 OAG16862.1 - 6.6e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG16862.1 - 5.2e-08 33.5 0.0 1.3e-07 32.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG16862.1 - 0.0011 19.6 0.0 0.0019 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Lactamase_B_6 PF16661.5 OAG16864.1 - 4.2e-66 222.1 0.0 6.5e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAG16864.1 - 1.6e-47 161.9 3.5 2.6e-47 161.2 0.0 2.5 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAG16864.1 - 7.1e-19 68.1 0.0 4.5e-18 65.5 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 OAG16864.1 - 5.1e-13 48.7 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain TamB PF04357.13 OAG16864.1 - 0.025 13.8 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Lactamase_B PF00753.27 OAG16864.1 - 0.026 14.5 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DTHCT PF08070.11 OAG16864.1 - 0.3 11.8 5.3 1.4 9.7 5.3 2.1 1 0 0 1 1 1 0 DTHCT (NUC029) region Fungal_trans_2 PF11951.8 OAG16866.1 - 9.2e-56 189.3 0.0 1.5e-55 188.6 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16866.1 - 3.4e-09 36.7 11.9 6e-09 35.9 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 OAG16869.1 - 3.1e-45 154.2 32.1 1.6e-25 89.8 13.2 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAG16869.1 - 4.6e-36 124.3 0.8 8.1e-22 78.2 0.0 2.8 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OAG16869.1 - 7.8e-09 35.8 0.4 0.067 13.0 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG16869.1 - 9.3e-07 28.5 0.0 0.0022 17.4 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG16869.1 - 0.00018 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OAG16869.1 - 0.00053 20.4 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OAG16869.1 - 0.00082 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG16869.1 - 0.0069 16.7 0.0 0.024 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 OAG16869.1 - 0.0092 16.2 0.2 17 5.7 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 OAG16869.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAG16869.1 - 0.024 14.2 0.4 0.13 11.8 0.0 2.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 OAG16869.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 OAG16869.1 - 0.029 14.1 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4388 PF14332.6 OAG16869.1 - 0.049 13.9 0.0 12 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4388) PDR_assoc PF08370.11 OAG16869.1 - 0.087 12.6 0.4 0.66 9.8 0.4 2.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_5 PF07728.14 OAG16869.1 - 0.13 12.3 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 OAG16869.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 OAG16869.1 - 0.24 10.6 1.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_61 PF03443.14 OAG16871.1 - 2.9e-47 161.3 0.1 3.8e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RuBisCO_large PF00016.20 OAG16871.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Cu_amine_oxid PF01179.20 OAG16872.1 - 1.6e-160 534.6 0.1 1.9e-160 534.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG16872.1 - 1.2e-12 47.8 0.1 2.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG16872.1 - 8.6e-05 22.9 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain CSTF2_hinge PF14327.6 OAG16873.1 - 1.1e-32 112.3 2.9 1.1e-32 112.3 2.9 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAG16873.1 - 1.1e-18 66.7 0.0 1.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAG16873.1 - 6e-06 25.7 10.4 6e-06 25.7 10.4 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal ZapB PF06005.12 OAG16874.1 - 0.00073 19.9 45.1 0.0064 16.9 7.6 5.2 4 1 1 5 5 5 2 Cell division protein ZapB Spc7 PF08317.11 OAG16874.1 - 0.00076 18.4 36.6 0.0016 17.4 14.2 3.2 1 1 0 2 2 2 2 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 OAG16874.1 - 0.01 16.4 7.3 0.01 16.4 7.3 4.2 3 1 2 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 OAG16874.1 - 0.028 14.2 0.6 0.028 14.2 0.6 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Macoilin PF09726.9 OAG16874.1 - 0.039 12.5 27.2 0.072 11.7 27.2 1.4 1 0 0 1 1 1 0 Macoilin family RPW8 PF05659.11 OAG16874.1 - 0.092 12.4 5.0 1.3 8.7 0.2 3.5 4 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4201 PF13870.6 OAG16874.1 - 0.15 11.7 26.1 0.37 10.5 8.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF5082 PF16888.5 OAG16874.1 - 0.19 12.0 30.5 0.43 10.9 0.2 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) WEMBL PF05701.11 OAG16874.1 - 0.31 9.7 28.2 0.49 9.0 28.2 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TMF_TATA_bd PF12325.8 OAG16874.1 - 0.55 10.5 29.5 0.93 9.7 6.9 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 OAG16874.1 - 0.58 10.4 40.3 3.3 7.9 15.3 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 OAG16874.1 - 0.64 10.4 31.7 4 7.9 0.3 5.5 5 0 0 5 5 4 0 Csm1 N-terminal domain Baculo_PEP_C PF04513.12 OAG16874.1 - 1.1 9.3 24.2 1.1 9.2 1.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WDCP PF15390.6 OAG16874.1 - 1.5 7.1 16.0 0.95 7.8 7.5 2.2 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family Fib_alpha PF08702.10 OAG16874.1 - 1.8 8.8 29.7 0.63 10.2 5.9 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 OAG16874.1 - 3 7.4 38.9 0.13 11.8 13.6 3.3 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 OAG16874.1 - 3.3 7.5 35.5 1 9.2 27.5 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CorA PF01544.18 OAG16874.1 - 3.9 6.7 25.5 0.45 9.8 13.0 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.6 OAG16874.1 - 5.9 7.3 40.1 0.84 10.1 10.9 3.7 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) GAS PF13851.6 OAG16874.1 - 9.7 5.5 38.2 0.93 8.8 2.3 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding adh_short PF00106.25 OAG16875.1 - 8.2e-38 129.8 0.2 1.1e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG16875.1 - 5.6e-26 91.5 0.2 8.2e-26 91.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG16875.1 - 2.6e-09 37.3 2.1 6.5e-08 32.7 2.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG16875.1 - 0.00031 20.3 0.0 0.00059 19.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG16875.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding UPF0146 PF03686.13 OAG16875.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Abhydrolase_3 PF07859.13 OAG16876.1 - 3.7e-44 151.1 0.0 4.7e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG16876.1 - 0.0074 15.2 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLIC PF05783.11 OAG16878.1 - 1.1e-32 113.5 0.5 1.4e-30 106.6 0.0 3.5 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 OAG16879.1 - 1.4e-16 60.1 0.2 9.3e-16 57.4 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG16879.1 - 0.00053 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 OAG16879.1 - 0.035 14.1 3.6 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Preseq_ALAS PF09029.10 OAG16880.1 - 0.00064 20.2 2.2 0.25 11.8 0.6 2.2 1 1 1 2 2 2 2 5-aminolevulinate synthase presequence VitK2_biosynth PF02621.14 OAG16880.1 - 0.16 11.4 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis zf-nanos PF05741.13 OAG16880.1 - 6 7.2 9.6 5 7.4 0.2 4.2 4 2 1 5 5 5 0 Nanos RNA binding domain Glyco_hydro_3_C PF01915.22 OAG16882.1 - 3.6e-48 164.2 0.0 7.4e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG16882.1 - 3.9e-35 121.8 0.0 6.1e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG16882.1 - 6.8e-24 83.8 0.2 1.2e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PC4 PF02229.16 OAG16884.1 - 2.3e-22 78.4 0.0 3.7e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) IFT43 PF15305.6 OAG16884.1 - 0.014 15.6 0.4 0.014 15.6 0.4 2.2 2 0 0 2 2 2 0 Intraflagellar transport protein 43 CRA PF06589.11 OAG16884.1 - 1.5 8.9 4.2 21 5.2 0.9 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) SurA_N PF09312.11 OAG16885.1 - 0.0011 19.0 2.5 0.0011 19.0 2.5 4.6 5 0 0 5 5 5 1 SurA N-terminal domain Tup_N PF08581.10 OAG16885.1 - 0.062 13.6 0.2 0.062 13.6 0.2 12.4 10 1 1 11 11 11 0 Tup N-terminal T7SS_ESX_EspC PF10824.8 OAG16885.1 - 0.13 12.8 11.0 0.37 11.3 1.3 5.5 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Minor_capsid_3 PF12691.7 OAG16885.1 - 5.3 7.4 14.9 1.4 9.3 0.5 4.9 4 0 0 4 4 4 0 Minor capsid protein from bacteriophage RPN6_N PF18055.1 OAG16886.1 - 2.4e-46 156.9 0.5 2.4e-46 156.9 0.5 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAG16886.1 - 1.7e-21 76.7 1.0 4.1e-21 75.5 0.2 2.1 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OAG16886.1 - 3.9e-10 39.3 0.5 1.4e-09 37.5 0.5 2.1 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 OAG16886.1 - 1.7e-06 27.6 3.2 0.00039 19.9 0.9 3.0 1 1 2 3 3 3 2 MalT-like TPR region TPR_12 PF13424.6 OAG16886.1 - 9.4e-06 25.8 11.0 0.27 11.6 0.5 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG16886.1 - 0.0027 18.4 4.1 2.1 9.4 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG16886.1 - 0.0033 17.9 3.9 0.31 11.6 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.9 OAG16886.1 - 0.0038 16.8 0.2 0.0087 15.7 0.2 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.6 OAG16886.1 - 0.0081 16.1 7.6 0.6 10.3 0.2 5.1 5 1 2 7 7 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG16886.1 - 0.011 15.4 2.1 2.9 7.7 0.0 3.6 4 0 0 4 4 4 0 TPR repeat DUF3496 PF12001.8 OAG16886.1 - 0.029 14.8 1.6 0.28 11.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_1 PF00515.28 OAG16886.1 - 0.04 13.8 3.0 9.7 6.2 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 OAG16886.1 - 0.079 12.7 8.5 0.12 12.0 0.8 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain NepR PF18557.1 OAG16886.1 - 0.079 12.6 0.0 0.25 11.0 0.0 2.0 1 0 0 1 1 1 0 Anti-sigma factor NepR DUF3090 PF11290.8 OAG16886.1 - 0.52 10.1 2.3 2.2 8.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) TPR_6 PF13174.6 OAG16886.1 - 0.62 10.8 6.5 11 7.0 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 OAG16886.1 - 0.7 9.9 7.1 0.13 12.2 1.5 2.6 3 1 1 4 4 4 0 Prefoldin subunit Prefoldin PF02996.17 OAG16886.1 - 0.96 9.4 5.7 0.62 10.0 0.1 3.0 4 0 0 4 4 4 0 Prefoldin subunit LPMO_10 PF03067.15 OAG16887.1 - 1.2e-08 35.8 0.6 4.3e-08 34.1 0.6 1.8 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RUN PF02759.19 OAG16887.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 RUN domain PocR PF10114.9 OAG16888.1 - 0.078 12.8 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR ADH_zinc_N PF00107.26 OAG16889.1 - 2.1e-13 50.4 0.0 3.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG16889.1 - 9.2e-12 46.2 0.0 2.1e-11 45.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG16889.1 - 4e-05 23.5 0.3 9e-05 22.3 0.3 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1189 PF06691.11 OAG16889.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Pectate_lyase PF03211.13 OAG16891.1 - 9.2e-86 286.6 8.8 1.1e-85 286.3 8.8 1.0 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG16891.1 - 0.02 14.7 1.8 0.031 14.1 1.8 1.3 1 0 0 1 1 1 0 Right handed beta helix region Osmo_MPGsynth PF09488.10 OAG16892.1 - 6.5e-67 225.9 0.0 7.3e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Mito_carr PF00153.27 OAG16893.1 - 5.7e-48 160.8 0.4 5.6e-17 61.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Biotin_carb_N PF00289.22 OAG16893.1 - 0.11 13.0 3.7 0.61 10.6 1.7 2.6 1 1 1 2 2 2 0 Biotin carboxylase, N-terminal domain NUDE_C PF04880.13 OAG16894.1 - 1.4e-42 146.1 13.0 1.4e-42 146.1 13.0 4.6 2 1 2 4 4 1 1 NUDE protein, C-terminal conserved region Tropomyosin_1 PF12718.7 OAG16894.1 - 0.19 11.8 35.7 3.9 7.6 4.5 3.5 2 1 1 3 3 3 0 Tropomyosin like PSII_Pbs27 PF13326.6 OAG16894.1 - 0.32 11.3 4.4 0.77 10.1 4.4 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF3584 PF12128.8 OAG16894.1 - 0.32 8.4 22.8 0.44 8.0 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 OAG16894.1 - 0.56 10.3 38.7 1.8 8.7 11.6 3.5 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 OAG16894.1 - 0.81 10.1 31.3 1.5 9.2 15.6 2.6 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 OAG16894.1 - 1.2 9.2 38.0 0.88 9.6 8.7 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 OAG16894.1 - 1.5 8.3 33.9 1.7 8.2 9.6 2.6 1 1 1 2 2 2 0 Intermediate filament protein PRKG1_interact PF15898.5 OAG16894.1 - 1.8 9.5 30.6 0.27 12.2 14.6 3.2 2 1 2 4 4 3 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 OAG16894.1 - 2 8.9 41.6 0.095 13.2 7.5 4.0 3 1 1 4 4 4 0 Cell division protein ZapB ERM PF00769.19 OAG16894.1 - 3.8 7.3 39.8 1.4 8.7 12.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APG6_N PF17675.1 OAG16894.1 - 7.3 7.1 44.9 2.7 8.5 7.9 3.2 1 1 1 3 3 3 0 Apg6 coiled-coil region DUF2968 PF11180.8 OAG16894.1 - 9.8 5.8 27.6 16 5.1 13.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) ACC_central PF08326.12 OAG16895.1 - 5.8e-277 920.8 0.0 7.2e-277 920.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAG16895.1 - 3.6e-186 619.6 0.0 6.4e-186 618.8 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAG16895.1 - 7.1e-53 179.2 0.0 1.4e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG16895.1 - 2.5e-28 98.8 0.1 4.9e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG16895.1 - 1.3e-21 76.7 0.0 1.7e-20 73.2 0.0 2.9 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG16895.1 - 3.5e-16 58.8 0.1 7.8e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG16895.1 - 0.00017 21.2 0.1 0.00067 19.2 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAG16895.1 - 0.00063 19.8 0.1 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG16895.1 - 0.037 13.9 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like GxGYxYP_N PF16216.5 OAG16895.1 - 0.04 14.1 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal RnfC_N PF13375.6 OAG16895.1 - 0.14 12.1 0.1 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 OAG16895.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ABM PF03992.16 OAG16896.1 - 0.0023 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 OAG16896.1 - 0.0027 16.9 0.1 0.0032 16.6 0.1 1.1 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition OSCP PF00213.18 OAG16896.1 - 0.01 16.0 0.1 0.011 15.9 0.1 1.0 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF2660 PF10859.8 OAG16896.1 - 0.14 12.7 1.2 1.7 9.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2660) Homeobox_KN PF05920.11 OAG16899.1 - 2.3e-18 65.8 0.4 4.2e-18 65.0 0.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG16899.1 - 6.4e-09 35.5 0.6 1.2e-08 34.7 0.6 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OAG16899.1 - 0.00048 19.6 0.1 0.026 14.0 0.0 2.7 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Cas9_PI PF16595.5 OAG16899.1 - 0.22 11.4 1.0 0.32 10.9 1.0 1.2 1 0 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 DHHC PF01529.20 OAG16900.1 - 5.6e-27 94.5 2.7 5.6e-27 94.5 2.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1772 PF08592.11 OAG16900.1 - 0.0013 19.0 1.0 0.017 15.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) URO-D PF01208.17 OAG16902.1 - 0.003 16.8 0.0 0.0036 16.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Sushi_2 PF09014.10 OAG16903.1 - 0.00063 19.6 0.3 0.00098 19.0 0.3 1.3 1 0 0 1 1 1 1 Beta-2-glycoprotein-1 fifth domain Arrestin_N PF00339.29 OAG16903.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Annexin PF00191.20 OAG16904.1 - 1.2e-55 185.4 4.9 1.6e-14 53.7 0.1 4.2 4 0 0 4 4 4 4 Annexin WASH-7_mid PF14744.6 OAG16904.1 - 0.13 11.3 0.2 0.27 10.3 0.1 1.5 1 1 0 1 1 1 0 WASH complex subunit 7 Acetyltransf_11 PF13720.6 OAG16904.1 - 0.24 11.9 0.6 35 5.0 0.0 3.0 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YlqD PF11068.8 OAG16904.1 - 0.48 10.8 4.6 12 6.3 0.5 2.6 2 1 0 2 2 2 0 YlqD protein Gly_transf_sug PF04488.15 OAG16907.1 - 1.9e-14 54.1 0.0 5.3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_transf_54 PF04666.13 OAG16909.1 - 2.1e-10 39.9 0.0 8.6e-07 28.1 0.0 2.9 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glycos_transf_2 PF00535.26 OAG16909.1 - 0.031 14.1 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 COX7a PF02238.15 OAG16909.1 - 7.9 7.0 6.1 2.6 8.5 0.5 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII AhpC-TSA_2 PF13911.6 OAG16910.1 - 3.8e-12 46.3 0.0 5.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OAG16910.1 - 2.1e-07 30.9 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG16910.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OAG16910.1 - 0.11 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like BTB PF00651.31 OAG16912.1 - 1.4e-10 41.3 0.0 1.1e-09 38.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Fungal_trans PF04082.18 OAG16912.1 - 1.4e-08 34.1 0.1 2.9e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG16912.1 - 8.4e-06 25.8 9.9 8.4e-06 25.8 9.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.7 OAG16913.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG16913.1 - 0.00025 21.4 0.0 0.00066 20.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG16913.1 - 0.00048 20.4 0.0 0.00071 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ANAPC4_WD40 PF12894.7 OAG16914.1 - 3.3e-07 30.5 0.2 0.0044 17.3 0.0 4.5 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG16914.1 - 0.034 15.0 0.2 31 5.7 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-CCCH PF00642.24 OAG16916.1 - 4e-09 36.1 10.8 3.5e-05 23.6 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG16916.1 - 8.6e-09 35.0 10.1 6.3e-06 25.9 2.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OAG16916.1 - 1.1e-07 32.6 7.2 0.00065 20.4 0.7 2.7 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OAG16916.1 - 4.2e-07 29.8 19.3 0.00047 20.1 3.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAG16916.1 - 6.3e-05 23.2 1.4 0.00015 22.0 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAG16916.1 - 0.29 11.7 13.5 0.93 10.1 2.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AMP-binding PF00501.28 OAG16917.1 - 3.8e-99 332.2 0.0 4.5e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG16917.1 - 1.9e-11 44.8 0.2 4.5e-11 43.6 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 OAG16918.1 - 3.4e-52 174.1 0.0 2.6e-16 59.2 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG16918.1 - 1.2e-05 24.9 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG16918.1 - 0.0012 18.9 0.1 3.5 7.8 0.0 3.4 3 1 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 OAG16918.1 - 0.0037 17.1 0.0 6.3 6.7 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif YoaP PF14268.6 OAG16918.1 - 0.088 12.3 2.2 3.3 7.3 0.0 2.9 3 0 0 3 3 3 0 YoaP-like PknH_C PF14032.6 OAG16918.1 - 0.098 12.5 0.2 25 4.7 0.0 3.0 3 0 0 3 3 3 0 PknH-like extracellular domain ATP-grasp_2 PF08442.10 OAG16918.1 - 0.11 12.1 0.0 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 ATP-grasp domain RRM_9 PF18444.1 OAG16918.1 - 0.19 11.6 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif THRAP3_BCLAF1 PF15440.6 OAG16918.1 - 1.2 8.1 25.0 1.5 7.7 25.0 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Mito_carr PF00153.27 OAG16919.1 - 8.8e-50 166.6 5.8 3.8e-19 68.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NYN PF01936.18 OAG16920.1 - 3.2e-05 24.5 0.1 0.00061 20.3 0.0 2.4 2 1 0 2 2 2 1 NYN domain DUF737 PF05300.11 OAG16920.1 - 0.0026 18.1 12.8 0.0026 18.1 12.8 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF737) MAT1 PF06391.13 OAG16920.1 - 1.2 8.9 11.6 2.1 8.1 11.6 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 PAP2_3 PF14378.6 OAG16921.1 - 3.3e-22 79.1 15.6 3.3e-22 79.1 15.6 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 OAG16921.1 - 2.2e-07 30.7 4.3 2.2e-07 30.7 4.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily Adaptin_N PF01602.20 OAG16922.1 - 1.2e-136 456.3 6.7 1.6e-136 456.0 6.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG16922.1 - 1.4e-62 210.6 5.0 1.6e-58 197.3 0.4 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG16922.1 - 3.3e-14 53.1 8.3 6.7e-06 26.4 0.1 5.6 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 OAG16922.1 - 3.2e-09 36.3 9.9 0.011 15.9 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.8 OAG16922.1 - 0.00018 21.2 0.1 0.76 9.3 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal UNC45-central PF11701.8 OAG16922.1 - 0.00035 20.6 0.4 0.36 10.8 0.1 3.0 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.23 OAG16922.1 - 0.0024 17.8 1.4 52 4.1 0.0 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 OAG16922.1 - 0.11 12.4 0.7 0.71 9.8 0.2 2.5 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CAAP1 PF15335.6 OAG16922.1 - 0.67 10.5 0.1 0.67 10.5 0.1 2.7 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 HEAT_EZ PF13513.6 OAG16922.1 - 2 9.0 6.8 8.9 6.9 0.0 5.1 5 1 1 6 6 6 0 HEAT-like repeat DUF3176 PF11374.8 OAG16923.1 - 8.4e-35 119.2 2.1 2.4e-34 117.7 2.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RVT_3 PF13456.6 OAG16923.1 - 0.14 11.9 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like F-box-like PF12937.7 OAG16924.1 - 0.00027 20.7 0.3 0.00052 19.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16924.1 - 0.00083 19.2 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain PhzC-PhzF PF02567.16 OAG16926.1 - 1.3e-37 129.9 0.1 1.7e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein BRCT_2 PF16589.5 OAG16928.1 - 1.2e-10 41.6 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OAG16928.1 - 0.003 17.5 0.3 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 OAG16928.1 - 0.091 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain XPG_I PF00867.18 OAG16929.1 - 3.5e-31 107.4 1.0 1.3e-30 105.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAG16929.1 - 2.8e-30 104.8 0.0 2.8e-30 104.8 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OAG16929.1 - 8.3e-08 32.7 0.7 1.9e-06 28.4 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 OAG16929.1 - 1 8.8 4.6 2.4 7.7 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AAA_23 PF13476.6 OAG16929.1 - 1.7 9.1 9.3 1.3 9.5 7.2 1.8 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_1 PF00441.24 OAG16930.1 - 1.3e-23 83.9 0.1 2.2e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG16930.1 - 1.8e-21 76.9 0.3 3.6e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG16930.1 - 2e-16 59.9 0.0 3.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG16930.1 - 1.8e-06 28.3 0.1 3.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 OAG16931.1 - 1.1e-52 177.4 0.0 1.2e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG16931.1 - 0.005 16.5 0.0 0.0061 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG16931.1 - 0.035 14.4 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAG16931.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NTP_transf_2 PF01909.23 OAG16932.1 - 0.00019 21.7 0.1 0.00059 20.1 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OAG16932.1 - 0.00024 21.3 0.0 0.00066 19.8 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase SWIRM-assoc_3 PF16498.5 OAG16932.1 - 0.071 13.4 0.4 0.36 11.1 0.4 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal tRNA_bind_2 PF13725.6 OAG16932.1 - 0.63 9.7 10.5 1.5 8.4 10.5 1.6 1 0 0 1 1 1 0 Possible tRNA binding domain Glyco_transf_20 PF00982.21 OAG16933.1 - 3.2e-147 491.0 0.0 4.5e-147 490.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG16933.1 - 2.1e-84 282.3 0.0 3.7e-84 281.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAG16933.1 - 0.00076 19.3 0.0 0.021 14.6 0.0 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4121 PF13497.6 OAG16933.1 - 0.091 11.9 0.4 0.19 10.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) MFS_1 PF07690.16 OAG16935.1 - 6e-27 94.5 64.8 2.3e-22 79.4 39.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG16935.1 - 2.1e-06 26.9 5.9 2.1e-06 26.9 5.9 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAG16935.1 - 0.061 11.6 3.5 0.15 10.3 3.5 1.8 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATP_synt_H PF05493.13 OAG16935.1 - 0.99 9.9 5.5 4.6 7.8 1.0 3.0 2 0 0 2 2 2 0 ATP synthase subunit H AA_permease_2 PF13520.6 OAG16936.1 - 1.6e-58 198.5 54.4 2e-58 198.2 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG16936.1 - 3.7e-14 52.2 53.2 6.8e-14 51.3 53.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF4690 PF15756.5 OAG16936.1 - 6 7.5 5.4 15 6.3 0.0 3.3 4 0 0 4 4 4 0 Small Novel Rich in Cartilage Presenilin PF01080.17 OAG16936.1 - 8.6 5.0 11.6 0.081 11.7 1.9 2.4 2 0 0 2 2 2 0 Presenilin Glyco_hydro_61 PF03443.14 OAG16937.1 - 6.7e-63 212.3 0.2 8e-63 212.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 OAG16937.1 - 0.032 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Clathrin_lg_ch PF01086.17 OAG16938.1 - 1.7e-78 263.8 4.7 2e-78 263.6 4.7 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.6 OAG16938.1 - 0.061 13.1 0.7 0.13 12.0 0.7 1.5 1 0 0 1 1 1 0 Integrase core domain Phosducin PF02114.16 OAG16938.1 - 0.073 12.0 1.8 0.11 11.4 1.8 1.2 1 0 0 1 1 1 0 Phosducin CdiI_2 PF18593.1 OAG16938.1 - 0.1 13.3 1.6 0.7 10.6 0.1 2.5 2 1 0 2 2 2 0 CdiI immunity protein CTD_bind PF04818.13 OAG16939.1 - 7.3e-15 55.5 0.0 2.3e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 OAG16939.1 - 0.0083 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CDC37_N PF03234.14 OAG16940.1 - 4.9e-47 160.1 4.0 4.9e-47 160.1 4.0 3.0 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAG16940.1 - 9.8e-45 151.3 2.7 1.1e-44 151.2 0.0 2.4 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAG16940.1 - 7.2e-30 103.1 1.5 7.2e-30 103.1 1.5 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain MazE_antitoxin PF04014.18 OAG16940.1 - 0.09 12.7 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin 5_nucleotid_C PF02872.18 OAG16941.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Reo_sigmaC PF04582.12 OAG16942.1 - 0.3 11.4 2.3 0.54 10.5 0.1 2.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein C-terminal domain NMO PF03060.15 OAG16943.1 - 2e-33 116.2 9.5 1.5e-27 96.9 5.3 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAG16943.1 - 9e-09 34.8 0.2 1.2e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG16943.1 - 1.3e-08 34.4 0.1 2.1e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG16943.1 - 9e-07 28.2 1.8 0.00012 21.2 1.9 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 OAG16943.1 - 0.027 14.0 0.7 0.055 12.9 0.2 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 OAG16943.1 - 0.07 12.4 0.4 0.11 11.7 0.4 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 OAG16943.1 - 0.18 11.0 0.3 0.32 10.2 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glyco_hydro_125 PF06824.11 OAG16944.1 - 1.3e-166 554.6 0.1 1.5e-166 554.4 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) COG4 PF08318.12 OAG16945.1 - 2.3e-119 398.4 0.0 3.3e-119 397.9 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Spc7 PF08317.11 OAG16945.1 - 0.21 10.4 1.7 0.34 9.8 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mg_trans_NIPA PF05653.14 OAG16946.1 - 1.7e-88 296.6 27.2 2.1e-88 296.2 27.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG16946.1 - 0.00047 20.3 5.4 0.00047 20.3 5.4 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF5362 PF17319.2 OAG16946.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.7 3 2 1 4 4 4 0 Family of unknown function (DUF5362) Deltameth_res PF16020.5 OAG16946.1 - 6.5 6.7 5.3 2.8 7.9 0.1 2.7 2 1 0 2 2 2 0 Deltamethrin resistance FAD_binding_3 PF01494.19 OAG16947.1 - 6.3e-26 91.4 0.0 1.4e-25 90.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAG16947.1 - 1.1e-07 31.5 0.0 8.8e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 OAG16947.1 - 7.9e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG16947.1 - 0.00026 20.4 0.3 0.33 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG16947.1 - 0.0011 19.5 2.0 0.02 15.5 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG16947.1 - 0.0011 18.2 0.4 0.85 8.6 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG16947.1 - 0.0058 16.8 0.2 0.016 15.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG16947.1 - 0.027 13.7 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG16947.1 - 0.088 11.5 0.1 3.8 6.1 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 OAG16947.1 - 0.16 11.2 0.1 0.32 10.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Peptidase_S10 PF00450.22 OAG16948.1 - 2.1e-82 277.8 0.6 2.6e-82 277.5 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MF_alpha_N PF05436.11 OAG16948.1 - 0.16 11.9 0.2 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus dCMP_cyt_deam_1 PF00383.23 OAG16949.1 - 6.5e-27 93.4 2.7 1e-26 92.8 2.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG16949.1 - 1.3e-09 37.9 0.1 2.1e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OAG16949.1 - 0.16 12.1 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 ATG7_N PF16420.5 OAG16950.1 - 2.4e-108 362.3 0.0 3.1e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAG16950.1 - 6.5e-42 143.6 0.0 1.2e-41 142.7 0.0 1.4 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAG16950.1 - 0.087 12.9 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 OAG16952.1 - 1.5e-22 80.0 26.5 1.5e-22 80.0 26.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 OAG16954.1 - 2.8e-43 147.7 0.0 7.5e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG16954.1 - 7.2e-36 124.2 31.3 1.6e-28 100.2 16.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG16954.1 - 6.1e-11 42.2 3.2 0.00052 19.5 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG16954.1 - 5.2e-07 29.3 0.7 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG16954.1 - 9.7e-07 29.3 0.4 0.069 13.5 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG16954.1 - 6.3e-06 26.2 1.4 0.15 11.9 0.1 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAG16954.1 - 1e-05 25.6 0.1 0.024 14.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG16954.1 - 1.1e-05 25.8 1.6 0.024 14.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAG16954.1 - 2.2e-05 24.4 0.1 0.068 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OAG16954.1 - 4.7e-05 23.0 0.0 0.088 12.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 OAG16954.1 - 7.4e-05 22.4 0.0 0.51 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG16954.1 - 0.00033 21.2 0.2 0.26 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG16954.1 - 0.00034 21.0 0.5 0.023 15.1 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG16954.1 - 0.0034 17.5 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OAG16954.1 - 0.0054 16.8 1.7 0.94 9.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family ABC_ATPase PF09818.9 OAG16954.1 - 0.0094 14.8 2.3 0.15 10.8 0.1 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class NB-ARC PF00931.22 OAG16954.1 - 0.012 14.8 0.1 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 OAG16954.1 - 0.014 15.3 0.4 6.4 6.7 0.1 2.8 3 0 0 3 3 2 0 NACHT domain DUF815 PF05673.13 OAG16954.1 - 0.014 14.5 0.2 4.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OAG16954.1 - 0.016 15.6 0.0 14 6.1 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ATPase_2 PF01637.18 OAG16954.1 - 0.027 14.4 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OAG16954.1 - 0.03 13.4 0.4 0.8 8.7 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 OAG16954.1 - 0.039 13.7 1.5 2 8.1 0.0 3.0 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 OAG16954.1 - 0.043 13.6 0.1 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 OAG16954.1 - 0.046 13.9 1.0 5.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAG16954.1 - 0.05 13.2 2.1 0.67 9.5 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3671 PF12420.8 OAG16954.1 - 0.053 13.6 2.3 1.5 8.9 0.0 3.4 3 0 0 3 3 2 0 Protein of unknown function IstB_IS21 PF01695.17 OAG16954.1 - 0.062 13.0 1.4 37 4.0 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein PduV-EutP PF10662.9 OAG16954.1 - 0.063 13.0 0.7 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 OAG16954.1 - 0.067 13.3 0.3 0.067 13.3 0.3 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_14 PF13173.6 OAG16954.1 - 0.09 12.8 0.2 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAG16954.1 - 0.098 12.4 0.3 4.8 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.11 OAG16954.1 - 0.11 11.4 0.7 8 5.3 0.2 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_15 PF13175.6 OAG16954.1 - 0.13 12.0 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF4064 PF13273.6 OAG16954.1 - 0.13 12.5 0.1 0.13 12.5 0.1 5.6 7 0 0 7 7 5 0 Protein of unknown function (DUF4064) AAA_5 PF07728.14 OAG16954.1 - 0.14 12.2 0.6 23 5.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG16954.1 - 0.14 11.8 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OAG16954.1 - 0.15 11.4 0.3 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 OAG16954.1 - 0.16 12.0 0.3 9.1 6.3 0.1 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 OAG16954.1 - 0.22 11.4 1.2 9.7 6.1 0.2 2.9 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 OAG16954.1 - 0.28 10.5 0.4 5.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 OAG16954.1 - 0.28 10.4 0.6 18 4.5 0.2 2.2 2 0 0 2 2 2 0 Septin Condensation PF00668.20 OAG16955.1 - 0 1294.7 0.0 1.4e-57 195.4 0.0 9.5 9 1 0 9 9 9 9 Condensation domain AMP-binding PF00501.28 OAG16955.1 - 7.8e-302 999.9 0.3 7.8e-78 261.9 0.2 4.6 5 0 0 5 5 5 4 AMP-binding enzyme PP-binding PF00550.25 OAG16955.1 - 2.1e-72 239.4 11.3 1.6e-12 47.5 0.1 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site Transferase PF02458.15 OAG16955.1 - 6.6e-07 28.3 0.0 0.4 9.3 0.0 3.9 4 0 0 4 4 4 3 Transferase family AMP-binding_C PF13193.6 OAG16955.1 - 8.9e-07 29.8 0.1 0.21 12.6 0.0 4.3 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain DUF600 PF04634.12 OAG16955.1 - 0.1 12.7 0.1 75 3.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF600 SLAC1 PF03595.17 OAG16956.1 - 1.3e-76 257.9 38.2 1.5e-76 257.7 38.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Bys1 PF04681.12 OAG16958.1 - 1.9e-11 44.1 0.1 2.5e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein F-box-like PF12937.7 OAG16959.1 - 1.4e-05 24.9 0.5 4.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG16959.1 - 0.15 12.0 0.7 1.1 9.2 0.7 2.3 1 1 0 1 1 1 0 F-box domain Pox_EPC_I2-L1 PF12575.8 OAG16959.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 F-box-like PF12937.7 OAG16960.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 OAG16960.1 - 0.12 12.3 1.3 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 F-box p450 PF00067.22 OAG16961.1 - 2.9e-27 95.5 0.0 4.1e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 OAG16963.1 - 0.00012 21.9 0.3 0.00028 20.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG16963.1 - 0.00066 19.5 0.3 0.0019 18.0 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG16963.1 - 0.0019 18.0 2.2 0.0035 17.2 0.1 2.5 3 1 0 3 3 3 1 F-box PQ-loop PF04193.14 OAG16969.1 - 4.6e-21 74.4 7.0 3.6e-20 71.5 1.4 2.9 2 1 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 OAG16969.1 - 0.18 11.4 10.5 0.067 12.7 5.8 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Presenilin PF01080.17 OAG16969.1 - 1.7 7.3 5.1 2.9 6.5 5.1 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_U4 PF03419.13 OAG16969.1 - 1.9 7.7 9.5 0.74 9.0 6.1 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA MtN3_slv PF03083.16 OAG16969.1 - 2.9 8.0 7.3 0.29 11.2 1.4 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange MFS_1 PF07690.16 OAG16970.1 - 1.9e-25 89.6 28.1 1.9e-25 89.6 28.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 OAG16970.1 - 0.11 12.3 0.9 7.7 6.4 0.0 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain F-box PF00646.33 OAG16971.1 - 9.1e-05 22.2 2.2 0.00012 21.9 0.7 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG16971.1 - 0.0015 18.4 1.6 0.0046 16.8 1.1 2.1 2 0 0 2 2 2 1 F-box-like zf-C2H2 PF00096.26 OAG16971.1 - 0.045 14.2 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type OsmC PF02566.19 OAG16973.1 - 6.4e-15 55.5 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein PPR PF01535.20 OAG16974.1 - 0.0093 16.1 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 1 PPR repeat UvrD_C PF13361.6 OAG16974.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PPR_2 PF13041.6 OAG16974.1 - 0.053 13.7 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family COX7a PF02238.15 OAG16975.1 - 1.3e-16 60.7 0.2 1.5e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII DUF1682 PF07946.14 OAG16976.1 - 3.6e-113 378.0 2.5 4.1e-113 377.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Glyco_hydro_18 PF00704.28 OAG16977.1 - 2.2e-06 27.6 0.0 2.5e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 YccJ PF13993.6 OAG16977.1 - 0.0074 16.6 0.0 0.66 10.3 0.0 2.3 2 0 0 2 2 2 2 YccJ-like protein eIF-5a PF01287.20 OAG16978.1 - 6.3e-05 23.0 0.2 0.00012 22.1 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 2OG-FeII_Oxy PF03171.20 OAG16979.1 - 5.1e-12 46.2 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG16979.1 - 1.3e-08 35.5 0.1 4e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CH PF00307.31 OAG16981.1 - 6.5e-77 254.8 0.2 9.1e-21 74.1 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OAG16981.1 - 5.9e-06 26.6 1.3 2.6e-05 24.6 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 OAG16981.1 - 0.0019 18.0 0.0 0.68 9.8 0.0 3.5 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.32 OAG16981.1 - 0.0028 17.1 1.5 1.2 8.8 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OAG16981.1 - 0.0046 16.8 0.4 0.16 12.0 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain eIF-1a PF01176.19 OAG16981.1 - 0.044 13.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 KilA-N PF04383.13 OAG16982.1 - 6.4e-05 22.8 0.0 0.00094 19.0 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain p450 PF00067.22 OAG16983.1 - 1.8e-52 178.6 0.0 3.4e-52 177.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Sec7_N PF12783.7 OAG16983.1 - 0.19 11.6 0.7 4.4 7.2 0.2 2.9 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SSXRD PF09514.10 OAG16984.1 - 0.013 15.1 0.8 0.027 14.0 0.8 1.6 1 0 0 1 1 1 0 SSXRD motif JmjC PF02373.22 OAG16984.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase FAD_binding_4 PF01565.23 OAG16985.1 - 3.5e-20 72.2 3.1 7.2e-20 71.2 3.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG16985.1 - 2.9e-05 24.1 0.2 4.9e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.7 OAG16987.1 - 6.4e-14 53.1 0.4 1.5e-13 51.8 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG16987.1 - 2.7e-11 43.6 0.0 2.8e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG16987.1 - 0.011 15.0 0.0 0.037 13.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 OAG16987.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 OAG16987.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Sof1 PF04158.14 OAG16988.1 - 1.3e-31 108.7 16.2 2.9e-31 107.6 16.2 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAG16988.1 - 3.5e-29 100.4 8.1 1.2e-07 32.3 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG16988.1 - 1.4e-10 41.3 0.1 0.03 14.6 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAG16988.1 - 6.6e-05 21.4 0.0 0.21 9.8 0.0 2.9 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 OAG16988.1 - 0.00042 20.2 0.3 0.026 14.4 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAG16988.1 - 0.0036 16.3 0.0 0.37 9.7 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L27e PF01777.18 OAG16989.1 - 1.2e-36 124.9 8.5 1.5e-36 124.6 8.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAG16989.1 - 0.00014 21.7 0.2 0.00042 20.2 0.2 1.8 1 0 0 1 1 1 1 KOW motif Perilipin PF03036.16 OAG16990.1 - 0.008 15.3 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 Perilipin family RNA_pol_Rpb1_5 PF04998.17 OAG16991.1 - 5.3e-89 298.2 0.1 1.6e-88 296.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG16991.1 - 9.6e-68 227.6 0.2 2e-67 226.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAG16991.1 - 7.7e-33 113.7 0.0 2.1e-32 112.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAG16991.1 - 4.7e-28 98.4 3.6 7.4e-23 81.4 0.3 3.5 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAG16991.1 - 4.8e-19 68.3 0.0 4.2e-18 65.2 0.0 2.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Thioredoxin PF00085.20 OAG16991.1 - 0.071 13.1 0.2 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin PRP3 PF08572.10 OAG16992.1 - 2.3e-66 223.7 2.0 4.9e-66 222.7 2.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAG16992.1 - 2.1e-43 147.9 0.0 2.1e-43 147.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.12 OAG16992.1 - 0.14 12.3 0.1 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Sensors of blue-light using FAD Glucos_trans_II PF14264.6 OAG16993.1 - 0.0079 15.6 0.6 0.019 14.3 0.6 1.6 1 1 0 1 1 1 1 Glucosyl transferase GtrII muHD PF10291.9 OAG16994.1 - 7.3e-75 251.8 0.0 1e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAG16994.1 - 9.2e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RE_AlwI PF09491.10 OAG16994.1 - 0.0078 15.1 0.3 0.011 14.6 0.3 1.1 1 0 0 1 1 1 1 AlwI restriction endonuclease DUF885 PF05960.11 OAG16994.1 - 0.0098 15.6 4.0 0.023 14.3 4.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Pkinase PF00069.25 OAG16995.1 - 3.7e-37 128.1 0.0 4.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG16995.1 - 2.4e-14 53.2 0.0 3.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KIX_2 PF16987.5 OAG16995.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 KIX domain APH PF01636.23 OAG16995.1 - 0.0095 15.9 0.0 0.69 9.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG16995.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OAG16995.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 OAG16995.1 - 0.094 12.2 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OAG16995.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mo25 PF08569.11 OAG16996.1 - 1.9e-128 428.5 0.2 2.1e-128 428.3 0.2 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.11 OAG16996.1 - 0.12 12.4 0.3 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus TPT PF03151.16 OAG16997.1 - 1.3e-21 77.3 10.8 2.1e-21 76.6 10.8 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG16997.1 - 8.5e-06 26.0 30.1 0.01 16.0 7.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAG16997.1 - 0.014 14.6 19.2 0.014 14.6 16.1 2.0 2 0 0 2 2 2 0 UAA transporter family DUF3767 PF12597.8 OAG16997.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) CDC45 PF02724.14 OAG16997.1 - 0.11 10.8 7.0 0.15 10.3 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAG16997.1 - 0.98 9.5 14.2 0.41 10.7 11.8 1.5 1 1 0 1 1 1 0 YL1 nuclear protein STIMATE PF12400.8 OAG16998.1 - 3.6e-43 147.1 2.7 3.6e-43 147.1 2.7 1.5 2 0 0 2 2 2 1 STIMATE family FKBP_C PF00254.28 OAG16998.1 - 2.9e-32 110.9 0.0 4.8e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAP PF07174.11 OAG16998.1 - 0.38 10.2 14.4 0.65 9.4 14.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) VEFS-Box PF09733.9 OAG16998.1 - 0.72 9.7 1.6 1.4 8.7 1.6 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein zf-C2H2_assoc2 PF16624.5 OAG16998.1 - 2.5 9.2 8.8 6.9 7.8 8.8 1.7 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger CoA_trans PF01144.23 OAG16999.1 - 3.6e-102 340.3 0.6 8.7e-63 211.6 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 OAG16999.1 - 0.0033 15.8 0.4 0.051 11.9 0.2 2.0 2 0 0 2 2 2 2 Malonate decarboxylase, alpha subunit, transporter Fungal_trans_2 PF11951.8 OAG17000.1 - 7.8e-17 61.1 0.1 1.8e-16 60.0 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17000.1 - 7.7e-05 22.7 7.8 0.00019 21.5 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pet191_N PF10203.9 OAG17001.1 - 1.6e-27 95.6 2.7 2e-27 95.2 2.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 OAG17001.1 - 0.11 12.6 1.5 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_1 PF00561.20 OAG17002.1 - 2.1e-24 86.6 0.1 4e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAG17002.1 - 4.2e-20 71.1 0.1 8.4e-20 70.1 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OAG17002.1 - 0.0001 21.6 0.0 0.052 12.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG17002.1 - 0.00021 21.0 0.1 0.0034 17.1 0.1 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Myc_target_1 PF15179.6 OAG17002.1 - 0.88 9.4 6.7 2.8 7.8 6.7 1.9 1 0 0 1 1 1 0 Myc target protein 1 Fungal_trans PF04082.18 OAG17003.1 - 3.1e-14 52.6 0.2 5.2e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17003.1 - 5.7e-10 39.2 14.0 1.1e-09 38.2 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycoamylase PF10091.9 OAG17004.1 - 0.028 14.0 0.2 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative glucoamylase bZIP_1 PF00170.21 OAG17006.1 - 1.9e-14 53.5 8.1 3.2e-14 52.8 8.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG17006.1 - 6.3e-07 29.4 8.0 1.3e-06 28.4 8.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG17006.1 - 0.00036 21.0 5.0 0.00041 20.8 3.6 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 OAG17006.1 - 0.058 12.8 0.8 0.088 12.2 0.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M WD40 PF00400.32 OAG17007.1 - 1.2e-16 60.7 7.0 5.6e-05 23.8 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG17007.1 - 2.9e-07 30.7 0.0 0.056 13.7 0.0 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG17007.1 - 0.00029 19.9 1.4 2.1 7.2 0.0 3.7 3 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AMP-binding PF00501.28 OAG17008.1 - 3.1e-83 279.8 0.0 3.9e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG17008.1 - 1.3e-15 58.1 0.3 3.7e-15 56.7 0.4 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.12 OAG17008.1 - 0.039 13.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain 3HCDH_N PF02737.18 OAG17009.1 - 1.2e-35 123.0 0.0 1.9e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG17009.1 - 1.8e-13 50.9 0.1 6.7e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MBOAT PF03062.19 OAG17010.1 - 4.1e-44 151.4 16.4 4.1e-44 151.4 16.4 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAG17010.1 - 0.0013 19.0 5.1 0.0045 17.2 5.1 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Lin-8 PF03353.15 OAG17010.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4501 PF14946.6 OAG17011.1 - 0.31 11.1 0.1 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) Helo_like_N PF17111.5 OAG17013.1 - 2.8e-05 23.6 2.7 7.7e-05 22.2 2.7 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FliS PF02561.14 OAG17013.1 - 0.00059 20.1 0.7 1.4 9.3 0.1 2.6 2 0 0 2 2 2 2 Flagellar protein FliS DUF3038 PF11237.8 OAG17013.1 - 0.011 15.8 1.5 0.013 15.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) AMP-binding PF00501.28 OAG17015.1 - 3.6e-95 319.1 0.0 5.1e-95 318.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RabGAP-TBC PF00566.18 OAG17015.1 - 5.8e-47 160.1 0.1 9e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AMP-binding_C PF13193.6 OAG17015.1 - 2.3e-20 73.3 0.1 6e-20 72.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.6 OAG17015.1 - 0.00047 19.9 0.7 0.062 13.3 0.2 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OAG17015.1 - 0.019 14.5 1.3 0.33 10.6 0.6 3.3 3 0 0 3 3 3 0 EF hand DUF1967 PF09269.11 OAG17015.1 - 0.036 14.0 0.1 3.5 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) EF-hand_5 PF13202.6 OAG17015.1 - 0.093 12.3 0.3 0.4 10.2 0.2 2.2 2 0 0 2 2 2 0 EF hand GRAM PF02893.20 OAG17015.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain EF-hand_7 PF13499.6 OAG17015.1 - 0.28 11.7 6.4 0.13 12.7 0.6 3.5 3 1 1 4 4 4 0 EF-hand domain pair adh_short_C2 PF13561.6 OAG17016.1 - 8.1e-55 185.9 0.1 1.1e-54 185.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17016.1 - 1.3e-42 145.5 0.1 1.7e-42 145.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17016.1 - 1.8e-12 47.5 0.1 2.7e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG17016.1 - 0.0038 16.7 0.1 0.0097 15.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG17016.1 - 0.054 13.4 0.0 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG17016.1 - 0.064 12.6 0.0 7.9 5.8 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Exo_endo_phos PF03372.23 OAG17017.1 - 0.00019 21.1 0.1 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rad21_Rec8_N PF04825.13 OAG17021.1 - 1.7e-31 108.6 0.0 3.2e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAG17021.1 - 2.5e-08 33.1 0.0 5.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Fungal_trans PF04082.18 OAG17022.1 - 5.8e-22 78.0 0.1 8.2e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17022.1 - 2.3e-10 40.4 9.1 3.6e-10 39.8 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.13 OAG17023.1 - 1.2e-99 333.9 0.9 2.7e-91 306.3 0.6 2.0 2 0 0 2 2 2 2 PrpF protein E1-E2_ATPase PF00122.20 OAG17024.1 - 2e-46 157.8 0.1 5.5e-46 156.4 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG17024.1 - 4.3e-42 143.9 0.4 8.5e-42 142.9 0.4 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG17024.1 - 5e-19 69.4 6.5 4.8e-18 66.2 6.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG17024.1 - 9.2e-18 63.7 0.0 1.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG17024.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG17024.1 - 0.00035 20.4 1.8 0.00067 19.5 1.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_A24 PF01478.18 OAG17024.1 - 0.0017 18.7 0.0 3.9 7.9 0.0 3.2 3 1 0 3 3 3 2 Type IV leader peptidase family Fungal_trans PF04082.18 OAG17025.1 - 3.3e-07 29.6 0.8 5.5e-07 28.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17025.1 - 0.00036 20.6 4.2 0.00036 20.6 4.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.29 OAG17026.1 - 3.4e-10 40.1 0.0 7.9e-10 39.0 0.0 1.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG17026.1 - 0.0074 15.7 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Bul1 C terminus SLD5_C PF16922.5 OAG17027.1 - 1.2e-17 63.8 0.4 2e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAG17027.1 - 8.9e-05 22.9 0.2 0.00017 22.0 0.2 1.5 1 1 0 1 1 1 1 GINS complex protein HTH_Tnp_Tc5 PF03221.16 OAG17028.1 - 3.2e-10 39.9 0.0 6.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG17028.1 - 0.0015 18.3 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_6 PF01418.17 OAG17028.1 - 0.0022 17.9 0.0 0.069 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 OAG17028.1 - 0.062 13.1 0.2 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain GntR PF00392.21 OAG17028.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_49 PF18010.1 OAG17028.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain Borrelia_P83 PF05262.11 OAG17029.1 - 0.25 9.8 9.5 0.32 9.4 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein YabA PF06156.13 OAG17029.1 - 0.27 11.9 1.7 0.55 10.9 1.7 1.6 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 OAG17029.1 - 2.7 7.8 7.9 0.55 10.0 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator FTA4 PF13093.6 OAG17030.1 - 9.1e-51 172.6 3.4 1.1e-50 172.4 3.4 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ABC_tran_CTD PF16326.5 OAG17030.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain vATP-synt_E PF01991.18 OAG17030.1 - 0.1 12.0 0.4 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Arrestin_N PF00339.29 OAG17031.1 - 2.9e-08 33.9 0.0 7.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Wzt_C PF14524.6 OAG17031.1 - 0.033 14.2 0.4 4.2 7.4 0.1 2.2 1 1 1 2 2 2 0 Wzt C-terminal domain FMN_bind_2 PF04299.12 OAG17032.1 - 2.8e-58 196.4 0.2 3.3e-58 196.1 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Amidase PF01425.21 OAG17033.1 - 2.4e-123 412.4 0.0 3.1e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.22 OAG17035.1 - 1.4e-58 198.7 0.0 2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hyccin PF09790.9 OAG17036.1 - 0.017 14.2 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Hyccin Pcc1 PF09341.10 OAG17038.1 - 9.7e-31 105.7 0.2 1.2e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 RNase_T PF00929.24 OAG17039.1 - 0.074 13.6 0.0 0.97 10.0 0.0 2.5 2 1 0 2 2 2 0 Exonuclease zinc_ribbon_4 PF13717.6 OAG17039.1 - 0.16 11.9 2.1 0.23 11.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 OAG17039.1 - 0.26 11.1 1.6 0.41 10.4 0.5 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF676 PF05057.14 OAG17040.1 - 2.6e-53 180.8 0.0 4.1e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 OAG17040.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG17040.1 - 0.00037 21.2 0.0 0.00057 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG17040.1 - 0.0057 16.5 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAG17040.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.11 OAG17040.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain GGACT PF06094.12 OAG17041.1 - 1.1e-08 35.7 0.0 1.9e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Clr5 PF14420.6 OAG17042.1 - 1.9e-14 53.6 0.7 2.6e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 Clr5 domain Ank_2 PF12796.7 OAG17043.1 - 9.6e-13 48.5 0.2 0.0018 18.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG17043.1 - 2.8e-10 40.5 0.1 0.01 16.4 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG17043.1 - 2.2e-07 30.6 0.0 0.46 11.2 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG17043.1 - 6.2e-05 23.2 0.0 0.9 9.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) YycH PF07435.11 OAG17043.1 - 0.015 14.3 0.3 0.022 13.8 0.3 1.1 1 0 0 1 1 1 0 YycH protein DHHC PF01529.20 OAG17045.1 - 1.2e-37 129.0 7.5 1.2e-37 129.0 7.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3955 PF13127.6 OAG17045.1 - 0.018 14.8 3.7 0.038 13.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Pex24p PF06398.11 OAG17046.1 - 0.02 13.9 0.5 0.019 14.0 0.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Telomerase_RBD PF12009.8 OAG17046.1 - 0.089 12.9 1.4 0.18 11.9 1.4 1.5 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain HAD_2 PF13419.6 OAG17048.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG17048.1 - 0.044 13.8 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Methyltransf_16 PF10294.9 OAG17050.1 - 4.2e-17 62.4 0.0 5.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG17050.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 OAG17050.1 - 0.047 13.0 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 OAG17050.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Copper-fist PF00649.18 OAG17051.1 - 2.7e-16 58.8 3.6 7.3e-16 57.4 3.6 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain SUN PF03856.13 OAG17052.1 - 1.3e-74 250.7 13.0 1.9e-74 250.2 13.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) FCH PF00611.23 OAG17054.1 - 3.3e-25 88.2 2.1 9.6e-25 86.7 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OAG17054.1 - 4.6e-18 64.8 0.1 3.7e-11 42.7 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain C1_1 PF00130.22 OAG17054.1 - 3.6e-15 55.6 4.8 5.6e-15 55.0 4.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 OAG17054.1 - 2.4e-14 52.6 0.2 2.6e-06 26.9 0.1 2.5 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 OAG17054.1 - 0.0021 18.3 5.4 0.0038 17.5 5.4 1.4 1 0 0 1 1 1 1 C1 domain SH3_3 PF08239.11 OAG17054.1 - 0.078 13.3 0.1 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4615 PF15393.6 OAG17054.1 - 4.3 7.9 15.6 0.26 11.9 1.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) DEAD PF00270.29 OAG17055.1 - 3e-33 115.1 0.2 8.3e-33 113.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG17055.1 - 3e-26 91.9 0.1 8.3e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG17055.1 - 0.0059 16.3 0.1 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG17055.1 - 0.01 16.1 2.1 0.061 13.6 2.1 2.3 1 1 0 1 1 1 0 AAA domain DUF202 PF02656.15 OAG17056.1 - 4.2e-23 81.6 0.3 4.2e-23 81.6 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) VMA21 PF09446.10 OAG17056.1 - 0.073 13.2 2.1 0.13 12.3 2.1 1.3 1 0 0 1 1 1 0 VMA21-like domain Anp1 PF03452.14 OAG17057.1 - 1.2e-109 365.8 0.1 1.5e-109 365.5 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OAG17057.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Myelin_MBP PF01669.17 OAG17057.1 - 0.03 14.9 1.6 0.037 14.6 0.1 1.7 2 0 0 2 2 2 0 Myelin basic protein YEATS PF03366.16 OAG17060.1 - 5e-18 64.9 0.0 9.9e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 OAG17060.1 - 2.3e-05 24.4 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 OAG17061.1 - 8.4e-49 164.9 1.5 1.6e-48 164.0 1.5 1.5 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 OAG17061.1 - 0.00097 19.4 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 VID27 PH-like domain WH1 PF00568.23 OAG17061.1 - 0.0012 18.7 0.1 0.0053 16.7 0.1 2.0 1 1 0 1 1 1 1 WH1 domain Glyco_transf_15 PF01793.16 OAG17062.1 - 1.3e-98 330.3 9.5 5.3e-98 328.3 9.5 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.6 OAG17063.1 - 9.4e-21 75.0 24.4 1.1e-20 74.8 24.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) SRP-alpha_N PF04086.13 OAG17063.1 - 1 9.3 18.2 1.2 9.0 18.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 OAG17063.1 - 7.3 4.8 12.7 8 4.6 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TraD PF06412.11 OAG17066.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TraD VIT1 PF01988.19 OAG17067.1 - 0.057 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 VIT family Comm PF15957.5 OAG17067.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Commissureless DUF4713 PF15831.5 OAG17067.1 - 6.4 7.3 8.4 13 6.3 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF2633 PF11119.8 OAG17068.1 - 1.1 9.2 3.9 32 4.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2633) EzrA PF06160.12 OAG17069.1 - 0.14 10.3 0.0 0.24 9.5 0.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_11 PF13086.6 OAG17070.1 - 7.5e-60 202.9 0.1 1.6e-59 201.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 OAG17070.1 - 7.7e-57 192.1 0.0 1.2e-55 188.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG17070.1 - 5.8e-12 45.7 0.1 8.5e-11 41.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG17070.1 - 1.6e-10 41.5 0.0 3e-09 37.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OAG17070.1 - 3.6e-07 29.8 0.6 1.6e-06 27.6 0.6 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OAG17070.1 - 1.1e-06 28.4 0.1 9.9e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OAG17070.1 - 2.1e-05 24.4 0.0 1.2 8.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG17070.1 - 2.2e-05 24.5 0.0 8.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 OAG17070.1 - 2.9e-05 23.8 0.0 0.075 12.9 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 OAG17070.1 - 6.3e-05 22.5 0.3 3.1 7.1 0.3 3.4 2 2 0 3 3 3 2 UvrD-like helicase C-terminal domain PhoH PF02562.16 OAG17070.1 - 0.00039 19.9 0.0 0.063 12.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 OAG17070.1 - 0.00059 20.1 0.2 0.0032 17.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OAG17070.1 - 0.00078 19.3 0.0 0.064 13.1 0.0 2.7 2 1 0 2 2 1 1 Helicase AAA_16 PF13191.6 OAG17070.1 - 0.0014 19.1 0.1 0.0033 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain 4HB_MCP_1 PF12729.7 OAG17070.1 - 0.002 17.7 0.8 0.0044 16.6 0.8 1.5 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction T2SSE PF00437.20 OAG17070.1 - 0.007 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 OAG17070.1 - 0.0073 15.9 0.2 0.14 11.7 0.0 2.6 2 1 1 3 3 2 1 AAA domain Flavi_DEAD PF07652.14 OAG17070.1 - 0.0082 16.1 0.1 0.022 14.7 0.1 1.8 1 1 0 2 2 2 1 Flavivirus DEAD domain PCB_OB PF17092.5 OAG17070.1 - 0.0095 16.7 1.9 0.86 10.4 0.3 2.7 1 1 1 2 2 2 1 Penicillin-binding protein OB-like domain AAA PF00004.29 OAG17070.1 - 0.024 15.1 0.1 0.061 13.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 OAG17070.1 - 0.034 13.5 0.2 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 OAG17070.1 - 0.037 14.2 0.7 0.16 12.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAG17070.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CpcD PF01383.21 OAG17070.1 - 0.048 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain AAA_24 PF13479.6 OAG17070.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG17070.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OAG17070.1 - 0.082 13.4 0.1 0.26 11.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter GNVR PF13807.6 OAG17070.1 - 0.11 12.4 1.5 0.19 11.7 0.5 2.0 2 0 0 2 2 1 0 G-rich domain on putative tyrosine kinase IstB_IS21 PF01695.17 OAG17070.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 OAG17070.1 - 0.17 11.8 0.3 10 6.0 0.1 2.6 2 1 1 3 3 2 0 Rad17 P-loop domain AAA_23 PF13476.6 OAG17070.1 - 0.36 11.3 8.0 2 8.8 0.0 2.6 2 1 0 3 3 2 0 AAA domain COesterase PF00135.28 OAG17072.1 - 2.2e-81 274.3 0.0 2.7e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG17072.1 - 1.3e-05 25.2 0.5 0.00011 22.2 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Catalase PF00199.19 OAG17073.1 - 1.5e-151 504.9 0.3 5.4e-96 322.0 0.0 2.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 OAG17073.1 - 4.8e-11 42.7 0.1 1.6e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF4959 PF16323.5 OAG17073.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4959) YfcL PF08891.11 OAG17073.1 - 0.2 12.0 0.0 0.51 10.7 0.0 1.6 1 1 0 1 1 1 0 YfcL protein DUF4246 PF14033.6 OAG17074.1 - 1.2e-173 578.4 0.3 1.4e-173 578.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 OAG17074.1 - 0.026 14.9 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase AA_permease_2 PF13520.6 OAG17075.1 - 9.8e-76 255.3 26.0 1.2e-75 255.0 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG17075.1 - 1.6e-19 69.8 22.6 2.3e-19 69.4 22.6 1.1 1 0 0 1 1 1 1 Amino acid permease Pectinesterase PF01095.19 OAG17076.1 - 2.8e-27 95.2 0.7 7.2e-24 84.0 1.5 2.1 2 0 0 2 2 2 2 Pectinesterase DUF3905 PF13045.6 OAG17076.1 - 0.02 14.9 0.0 0.062 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) IBR PF01485.21 OAG17077.1 - 4e-06 27.0 7.5 4e-06 27.0 7.5 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DNA_RNApol_7kD PF03604.13 OAG17077.1 - 2.6 7.8 17.3 2.2 8.1 0.1 4.7 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit p450 PF00067.22 OAG17078.1 - 7.2e-75 252.5 0.0 8.5e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotJA PF11007.8 OAG17078.1 - 0.14 12.0 0.1 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Spore coat associated protein JA (CotJA) Glyco_hydro_16 PF00722.21 OAG17079.1 - 1.2e-38 132.4 4.1 1.8e-38 131.8 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 OAG17079.1 - 0.39 11.2 10.7 1.1 9.8 10.7 1.7 1 0 0 1 1 1 0 Chitin recognition protein DSPc PF00782.20 OAG17080.1 - 2.3e-26 92.2 0.0 3.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAG17080.1 - 0.0016 18.8 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OAG17080.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG17080.1 - 0.035 14.2 0.1 0.076 13.1 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 OAG17080.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.6 OAG17080.1 - 0.097 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Peptidase_S28 PF05577.12 OAG17081.1 - 6.1e-54 183.5 1.6 1.2e-53 182.5 1.6 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Tsi6 PF18660.1 OAG17081.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Tsi6 Fungal_trans PF04082.18 OAG17082.1 - 3.6e-11 42.6 0.0 7.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17082.1 - 1.4e-06 28.3 11.0 2.3e-06 27.6 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.10 OAG17084.1 - 1e-52 178.5 0.0 1.3e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 COX5B PF01215.19 OAG17085.1 - 1.2e-55 186.6 0.0 1.8e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Isochorismatase PF00857.20 OAG17086.1 - 3e-33 115.5 1.2 6.6e-33 114.3 1.2 1.5 1 1 0 1 1 1 1 Isochorismatase family LpxI_N PF17930.1 OAG17086.1 - 0.049 13.5 0.0 0.19 11.7 0.0 1.8 1 1 1 2 2 2 0 LpxI N-terminal domain Oxysterol_BP PF01237.18 OAG17087.1 - 3.1e-92 309.3 0.0 1e-89 301.0 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein F-box PF00646.33 OAG17088.1 - 0.0014 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG17088.1 - 0.023 14.6 0.0 0.22 11.5 0.0 2.6 2 0 0 2 2 2 0 F-box-like TrkH PF02386.16 OAG17089.1 - 3.2e-102 342.6 4.0 1.8e-94 317.0 1.6 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1772 PF08592.11 OAG17089.1 - 1.4 9.2 5.3 5.1 7.4 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Myb_DNA-bind_6 PF13921.6 OAG17092.1 - 7.6e-05 22.9 0.0 0.0074 16.5 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG17092.1 - 0.00058 20.0 0.3 0.0011 19.1 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG17093.1 - 9.9e-09 35.3 0.2 0.0035 17.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG17093.1 - 0.00011 22.4 0.2 0.081 13.2 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1178 PF06676.11 OAG17093.1 - 0.032 14.6 0.9 0.041 14.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Myb_DNA-bind_6 PF13921.6 OAG17094.1 - 3.2e-13 49.7 0.3 2.1e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG17094.1 - 4.3e-10 39.6 0.0 6e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3646 PF12362.8 OAG17094.1 - 0.047 14.0 1.1 1.1 9.7 0.8 2.3 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal MFS_1 PF07690.16 OAG17098.1 - 6e-31 107.6 32.7 3.9e-23 82.0 2.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17098.1 - 2.1e-07 30.2 8.5 3.7e-07 29.4 0.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4405 PF14358.6 OAG17099.1 - 1.1 9.8 6.4 22 5.7 6.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) zf-C2H2_4 PF13894.6 OAG17100.1 - 0.11 13.4 0.4 1.6 9.8 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TENA_THI-4 PF03070.16 OAG17101.1 - 3.1e-07 30.4 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family zf-BED PF02892.15 OAG17101.1 - 0.0042 17.1 0.8 0.015 15.4 0.3 2.1 2 0 0 2 2 2 1 BED zinc finger Cellulase PF00150.18 OAG17102.1 - 3.4e-12 46.4 2.7 1.1e-11 44.7 2.7 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 OAG17102.1 - 0.0032 16.9 0.0 0.0081 15.5 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase GPI-anchored PF10342.9 OAG17103.1 - 6.6e-20 71.7 0.2 1.2e-19 70.8 0.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF963 PF06131.11 OAG17103.1 - 3.4 7.2 20.8 2.3 7.7 6.4 2.9 2 1 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) P53_tetramer PF07710.11 OAG17104.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 P53 tetramerisation motif F-box PF00646.33 OAG17106.1 - 0.0062 16.4 0.2 0.019 14.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain Epiglycanin_C PF14654.6 OAG17107.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region DUF5362 PF17319.2 OAG17107.1 - 0.47 10.3 5.4 0.31 10.9 2.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Sugar_tr PF00083.24 OAG17110.1 - 3.2e-86 290.0 25.4 4.1e-86 289.6 25.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17110.1 - 1.3e-15 57.2 37.3 2e-12 46.7 11.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAG17111.1 - 7.6e-15 55.3 0.0 4.7e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG17111.1 - 3.1e-08 33.4 0.1 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OAG17111.1 - 1.1e-05 24.5 0.0 7.1e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 OAG17111.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 Putative esterase DUF4381 PF14316.6 OAG17111.1 - 0.091 13.0 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) AAA PF00004.29 OAG17112.1 - 6.6e-18 65.4 0.0 2e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG17112.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG17112.1 - 0.00088 19.6 5.7 0.013 15.8 0.1 3.0 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 OAG17112.1 - 0.0011 19.4 0.1 0.0063 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 OAG17112.1 - 0.0043 17.5 0.1 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG17112.1 - 0.0054 16.9 0.0 0.05 13.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG17112.1 - 0.0065 17.0 0.0 0.037 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG17112.1 - 0.022 14.7 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAG17112.1 - 0.025 14.3 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 OAG17112.1 - 0.099 12.0 0.4 0.66 9.3 0.2 2.3 1 1 1 2 2 2 0 KaiC AIRS_C PF02769.22 OAG17113.1 - 2.5e-34 118.7 0.0 5.2e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 OAG17113.1 - 3.2e-13 50.1 1.2 9.7e-13 48.6 1.2 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 OAG17113.1 - 2.2e-12 47.0 0.1 6e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG17113.1 - 0.0002 21.7 0.0 0.0014 19.0 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Pribosyltran PF00156.27 OAG17114.1 - 7.2e-16 58.1 0.0 9.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG17114.1 - 0.0059 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1180 PF06679.12 OAG17114.1 - 0.12 12.8 6.6 0.17 12.3 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ribonuc_L-PSP PF01042.21 OAG17115.1 - 4.2e-39 133.3 0.0 4.7e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HET PF06985.11 OAG17116.1 - 1.8e-13 51.1 9.8 9.3e-12 45.5 2.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.6 OAG17116.1 - 2.2 8.1 6.8 2.9 7.7 0.4 2.4 2 0 0 2 2 2 0 Glycosyl transferase family group 2 HET PF06985.11 OAG17117.1 - 8.1e-13 48.9 1.5 3.1e-08 34.1 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AT_hook PF02178.19 OAG17118.1 - 0.074 13.0 7.4 0.24 11.4 7.4 1.9 1 0 0 1 1 1 0 AT hook motif SET PF00856.28 OAG17120.1 - 2.5e-11 44.3 0.2 9.9e-11 42.3 0.2 1.9 1 1 0 1 1 1 1 SET domain Bestrophin PF01062.21 OAG17121.1 - 8.2e-22 77.9 0.0 2.1e-21 76.6 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ApbA PF02558.16 OAG17122.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.13 OAG17123.1 - 1.8e-44 152.1 0.0 2.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG17123.1 - 2.7e-08 33.1 0.4 7.6e-08 31.7 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 OAG17123.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S51 PF03575.17 OAG17123.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 TPR_12 PF13424.6 OAG17124.1 - 2.5e-26 91.8 9.4 1.3e-07 31.8 0.5 7.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG17124.1 - 2e-18 65.6 11.6 0.23 11.4 0.0 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG17124.1 - 9.1e-06 25.2 1.9 2e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 OAG17124.1 - 3.4e-05 23.2 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 OAG17124.1 - 0.00087 19.2 9.4 11 6.4 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat LEA_5 PF00477.17 OAG17124.1 - 0.0017 18.8 0.6 0.0076 16.7 0.1 2.3 2 0 0 2 2 2 1 Small hydrophilic plant seed protein TPR_MalT PF17874.1 OAG17124.1 - 0.02 14.3 13.6 0.008 15.6 4.8 3.8 2 1 0 3 3 3 0 MalT-like TPR region DUF4477 PF14780.6 OAG17124.1 - 0.048 13.3 2.4 0.041 13.5 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF4047 PF13256.6 OAG17124.1 - 0.049 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) TPR_5 PF12688.7 OAG17124.1 - 0.26 11.5 0.0 0.26 11.5 0.0 3.3 5 0 0 5 5 5 0 Tetratrico peptide repeat Rx_N PF18052.1 OAG17124.1 - 0.3 11.4 2.5 0.69 10.2 0.8 2.6 2 0 0 2 2 1 0 Rx N-terminal domain TPR_4 PF07721.14 OAG17124.1 - 0.37 11.5 10.1 25 5.9 0.0 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17124.1 - 0.4 11.6 7.4 16 6.7 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG17124.1 - 0.96 9.6 4.7 7.2 6.9 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.22 OAG17126.1 - 2.7e-67 227.5 0.0 3.3e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 OAG17128.1 - 3.8e-29 101.9 1.4 6.8e-29 101.1 1.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAT PF04768.13 OAG17128.1 - 0.0083 15.8 0.6 2.4 7.8 0.1 3.1 2 1 1 3 3 3 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase adh_short PF00106.25 OAG17129.1 - 5.3e-23 81.5 2.7 1.9e-21 76.5 0.8 2.7 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.10 OAG17129.1 - 6.5e-15 55.5 0.3 9.9e-15 54.9 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG17129.1 - 5.4e-08 32.7 3.1 6e-08 32.5 1.0 2.0 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Peptidase_S9 PF00326.21 OAG17130.1 - 3.3e-46 157.4 0.7 4.8e-46 156.9 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG17130.1 - 1.6e-05 24.7 0.3 0.0097 15.8 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat CBM_20 PF00686.19 OAG17131.1 - 7.6e-35 118.7 0.9 1.3e-34 117.9 0.9 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 OAG17131.1 - 9.2e-10 39.5 2.2 2.1e-09 38.3 2.2 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 OAG17131.1 - 0.0014 18.6 0.6 0.0032 17.4 0.1 1.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 61 Ecotin PF03974.13 OAG17131.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Ecotin APH PF01636.23 OAG17132.1 - 4.9e-06 26.6 0.0 5.9e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 OAG17132.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase HET PF06985.11 OAG17133.1 - 1.6e-29 103.2 0.3 2.6e-29 102.5 0.3 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tim17 PF02466.19 OAG17135.1 - 9.2e-05 22.8 0.0 0.00021 21.6 0.0 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LapA_dom PF06305.11 OAG17135.1 - 3.6 7.5 4.2 58 3.6 0.0 2.7 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain tRNA-synt_2d PF01409.20 OAG17136.1 - 2.5e-84 282.6 0.0 3.3e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAG17136.1 - 1.3e-13 51.0 2.3 1.9e-13 50.5 0.5 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 OAG17136.1 - 5.4e-07 29.0 0.2 0.0012 18.0 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 OAG17136.1 - 3.9e-05 23.2 0.0 0.058 12.8 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain DUF3405 PF11885.8 OAG17137.1 - 6.7e-204 678.3 17.4 1.9e-202 673.5 17.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) CBM_5_12_2 PF14600.6 OAG17137.1 - 0.14 12.1 1.9 0.58 10.1 1.9 2.0 1 0 0 1 1 1 0 Cellulose-binding domain LicD PF04991.13 OAG17138.1 - 4.4e-12 46.6 20.2 9.1e-06 26.0 10.5 3.5 2 1 1 3 3 3 2 LicD family FAD_binding_4 PF01565.23 OAG17139.1 - 4.9e-20 71.7 1.3 8.8e-20 70.9 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG17139.1 - 2.2e-12 46.9 0.0 4.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.13 OAG17140.1 - 2e-48 165.0 0.0 2.4e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG17140.1 - 2.2e-12 47.3 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG17140.1 - 4.1e-06 26.0 0.1 6.9e-06 25.3 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG17140.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAG17141.1 - 2e-07 31.0 12.1 3.2e-07 30.4 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG17141.1 - 7.9e-05 21.8 0.1 7.9e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1388 PF07142.12 OAG17141.1 - 0.075 13.0 0.8 0.19 11.7 0.8 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Anth_Ig PF05587.13 OAG17141.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Anthrax receptor extracellular domain Hid1 PF12722.7 OAG17141.1 - 1.3 7.0 9.1 2 6.5 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MerR-DNA-bind PF09278.11 OAG17141.1 - 6.7 7.3 7.6 0.33 11.5 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding ThiS PF02597.20 OAG17142.1 - 5.6e-11 42.9 0.0 9.7e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 ThiS family RNB PF00773.19 OAG17143.1 - 3.2e-55 187.7 0.0 1e-54 186.1 0.0 1.9 1 1 0 1 1 1 1 RNB domain Fungal_trans PF04082.18 OAG17144.1 - 4.6e-15 55.4 0.0 1.5e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17144.1 - 1.2e-05 25.3 13.2 2.4e-05 24.3 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 OAG17145.1 - 8.2e-10 38.8 0.1 1.7e-09 37.7 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG17145.1 - 0.00022 21.9 0.2 0.00026 21.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CorA PF01544.18 OAG17146.1 - 7.4e-10 38.6 0.0 9.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF463 PF04317.12 OAG17146.1 - 0.11 11.4 1.5 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 YcjX-like family, DUF463 Ank_4 PF13637.6 OAG17147.1 - 2.1e-17 63.2 0.5 1.1e-11 45.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG17147.1 - 9e-17 59.5 0.5 6.8e-05 23.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OAG17147.1 - 3.7e-16 59.5 0.0 2.8e-11 43.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG17147.1 - 1.2e-13 50.8 1.7 0.03 14.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OAG17147.1 - 1.6e-12 47.4 1.2 0.00011 22.4 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG17148.1 - 0.00046 19.6 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Pkinase PF00069.25 OAG17150.1 - 2.8e-24 85.9 0.0 7.3e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG17150.1 - 1.7e-14 53.7 0.0 6.6e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase NB-ARC PF00931.22 OAG17150.1 - 0.00092 18.5 0.1 0.0023 17.2 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAG17150.1 - 0.02 15.2 1.2 0.19 12.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 OAG17150.1 - 0.06 13.7 0.0 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pox_ser-thr_kin PF05445.11 OAG17150.1 - 0.093 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HET PF06985.11 OAG17151.1 - 2.3e-27 96.2 2.2 4.9e-26 91.8 2.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FYVE PF01363.21 OAG17152.1 - 1.3e-21 76.5 1.0 1.3e-21 76.5 1.0 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 OAG17152.1 - 3.5e-08 33.6 23.5 2.1e-07 31.1 4.2 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAG17152.1 - 6.8e-05 22.6 3.2 6.8e-05 22.6 3.2 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG17152.1 - 0.00064 19.4 4.3 0.00064 19.4 4.3 3.0 4 0 0 4 4 3 1 RING-like zinc finger FYVE_2 PF02318.16 OAG17152.1 - 0.0084 16.3 0.9 0.0084 16.3 0.9 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 OAG17152.1 - 0.011 15.6 2.1 0.011 15.6 2.1 3.7 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 OAG17152.1 - 0.079 12.8 6.3 1.2 9.1 0.6 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif RNF220 PF15926.5 OAG17152.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 zf-ANAPC11 PF12861.7 OAG17152.1 - 0.69 10.0 6.8 1.9 8.6 2.3 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 OAG17152.1 - 1 9.4 8.6 24 5.1 0.1 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.6 OAG17152.1 - 2.9 8.0 24.7 0.067 13.2 2.0 3.7 3 0 0 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.8 OAG17152.1 - 3.7 7.8 11.3 0.19 11.9 3.0 2.8 3 0 0 3 3 3 0 FANCL C-terminal domain C1_2 PF03107.16 OAG17152.1 - 6.1 7.3 12.9 0.13 12.6 1.8 3.2 3 0 0 3 3 3 0 C1 domain TRP PF06011.12 OAG17153.1 - 5.3e-39 134.1 25.4 6.3e-37 127.3 25.4 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG17153.1 - 4.6e-18 65.9 0.0 7.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Mem_trans PF03547.18 OAG17154.1 - 0.021 13.3 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3328 PF11807.8 OAG17155.1 - 0.6 9.9 5.8 0.86 9.3 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) Ank_2 PF12796.7 OAG17156.1 - 3.4e-16 59.6 0.4 2e-14 53.9 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG17156.1 - 5.5e-15 55.5 0.1 1.8e-08 34.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG17156.1 - 3.3e-13 48.5 0.9 0.00021 21.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAG17156.1 - 1.6e-12 47.4 2.1 7.9e-06 26.1 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG17156.1 - 1.8e-11 43.9 1.1 0.00078 19.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.21 OAG17156.1 - 0.026 14.6 5.4 0.072 13.2 5.4 1.7 1 0 0 1 1 1 0 bZIP transcription factor SWIRM-assoc_2 PF16496.5 OAG17156.1 - 0.11 11.3 3.1 0.14 11.0 3.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MFS_2 PF13347.6 OAG17157.1 - 3.9e-08 32.3 8.9 3.9e-08 32.3 8.9 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3328 PF11807.8 OAG17158.1 - 0.011 15.6 3.0 0.071 12.9 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) CDH-cyt PF16010.5 OAG17159.1 - 1.2e-13 51.2 0.3 1.9e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAG17159.1 - 1.4e-05 25.3 11.4 1.4e-05 25.2 9.3 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF4191 PF13829.6 OAG17159.1 - 2.1 7.6 5.9 2.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF3563 PF12086.8 OAG17160.1 - 2.2e-06 27.3 24.4 6.8 6.5 0.2 7.6 1 1 9 10 10 10 10 Protein of unknown function (DUF3563) DUF3326 PF11805.8 OAG17160.1 - 7.1 5.4 9.9 13 4.5 3.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3326) MFS_1 PF07690.16 OAG17161.1 - 2.3e-13 49.8 32.1 3.7e-11 42.6 15.7 2.5 1 1 3 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17161.1 - 0.042 12.7 10.2 0.024 13.5 2.8 3.0 2 1 0 2 2 2 0 Sugar (and other) transporter ETRAMP PF09716.10 OAG17161.1 - 0.065 13.3 0.0 18 5.5 0.0 3.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) INSIG PF07281.12 OAG17161.1 - 0.12 11.9 1.4 0.93 9.1 0.6 2.7 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) CorA PF01544.18 OAG17162.1 - 1.9e-14 53.7 0.9 4.8e-14 52.4 0.3 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 OAG17162.1 - 7e-10 39.4 0.0 0.0021 18.6 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG17162.1 - 4.7e-08 33.4 0.0 0.00017 22.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAG17162.1 - 2.5e-06 28.0 0.0 1e-05 26.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAG17162.1 - 2.9e-06 27.3 0.0 6.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG17162.1 - 5.5e-06 26.7 0.0 3.3e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain Ank_3 PF13606.6 OAG17162.1 - 0.001 19.4 0.0 10 7.1 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat AAA PF00004.29 OAG17162.1 - 0.0017 18.8 0.0 0.0091 16.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 OAG17162.1 - 0.0062 16.8 0.0 0.77 10.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG17162.1 - 0.012 16.0 0.2 17 6.1 0.1 4.1 3 1 0 3 3 3 0 Ankyrin repeat DUF1593 PF07632.11 OAG17162.1 - 0.04 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Mg_chelatase PF01078.21 OAG17162.1 - 0.042 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAG17162.1 - 0.08 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 OAG17162.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG17162.1 - 0.12 12.0 0.0 0.82 9.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain Fic PF02661.18 OAG17163.1 - 3.6e-21 75.9 0.1 3.3e-20 72.8 0.0 2.4 2 1 0 3 3 3 1 Fic/DOC family Metallophos PF00149.28 OAG17164.1 - 2.6e-12 47.7 0.4 3.7e-12 47.2 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG17164.1 - 7e-08 32.8 0.1 9e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MARVEL PF01284.23 OAG17166.1 - 0.0011 19.0 15.6 0.0029 17.7 15.7 1.5 1 1 0 1 1 1 1 Membrane-associating domain Amidase PF01425.21 OAG17167.1 - 1.1e-97 327.8 0.0 2.2e-97 326.9 0.0 1.4 1 1 0 1 1 1 1 Amidase NB-ARC PF00931.22 OAG17167.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain GFA PF04828.14 OAG17168.1 - 6e-22 77.8 0.1 6e-22 77.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.8 OAG17168.1 - 1.6 9.0 8.3 0.49 10.6 1.2 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I PMSR PF01625.21 OAG17169.1 - 1.4e-62 210.4 0.8 1.6e-62 210.2 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4360 PF14273.6 OAG17170.1 - 1.4e-69 233.5 4.1 1.6e-69 233.3 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Kinesin PF00225.23 OAG17171.1 - 1.1e-117 392.7 0.0 1.7e-117 392.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG17171.1 - 6.6e-27 94.3 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 OAG17171.1 - 0.0074 16.5 1.3 0.023 15.0 1.3 1.8 1 0 0 1 1 1 1 Herpesvirus UL14-like protein ADH_zinc_N PF00107.26 OAG17172.1 - 1e-07 32.0 0.1 1.4e-06 28.3 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG17172.1 - 1.1e-05 25.3 0.0 4.6e-05 23.3 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG17172.1 - 0.0028 18.7 0.0 0.0063 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Bax1-I PF01027.20 OAG17173.1 - 8e-34 117.3 9.6 1.2e-33 116.8 9.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FATC PF02260.20 OAG17173.1 - 0.076 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 FATC domain GIT_CC PF16559.5 OAG17175.1 - 1.7 8.6 9.5 0.29 11.0 1.3 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OAG17175.1 - 2.1 9.0 6.4 0.84 10.3 0.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Dioxygenase_C PF00775.21 OAG17176.1 - 9.6e-05 21.9 0.1 0.00019 20.9 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase DUF3632 PF12311.8 OAG17177.1 - 4.8e-16 59.7 0.0 6.8e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) F-box-like PF12937.7 OAG17178.1 - 3.2e-06 26.9 0.9 6.5e-06 26.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like VirDNA-topo-I_N PF09266.10 OAG17178.1 - 0.053 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal FMO-like PF00743.19 OAG17180.1 - 2.1e-12 46.3 0.2 2.4e-09 36.2 0.2 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG17180.1 - 2.4e-12 46.9 0.0 7e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG17180.1 - 1.1e-06 28.1 0.0 6.5e-06 25.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG17180.1 - 1.2e-05 24.7 0.0 0.0073 15.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG17180.1 - 0.0002 20.6 0.1 4.2 6.4 0.0 3.7 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG17180.1 - 0.00083 19.0 0.0 0.34 10.5 0.0 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG17180.1 - 0.0013 18.8 0.0 0.0068 16.4 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG17180.1 - 0.073 12.3 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAG17180.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short_C2 PF13561.6 OAG17181.1 - 1.3e-55 188.5 0.4 1.6e-55 188.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17181.1 - 1.2e-45 155.3 0.3 1.6e-45 155.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17181.1 - 9.5e-11 41.9 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG17181.1 - 7.5e-07 28.9 0.2 2.4e-06 27.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Chordopox_A35R PF05989.12 OAG17181.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A35R protein ThiF PF00899.21 OAG17181.1 - 0.025 13.9 0.1 1.6 8.0 0.0 2.3 1 1 1 2 2 2 0 ThiF family Ldh_1_N PF00056.23 OAG17181.1 - 0.026 14.6 0.1 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PrpR_N PF06506.11 OAG17181.1 - 0.06 12.9 0.0 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator ApbA PF02558.16 OAG17181.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DNA_pol_lambd_f PF10391.9 OAG17181.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Acyl-CoA_dh_1 PF00441.24 OAG17183.1 - 7.1e-24 84.7 0.1 1.3e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG17183.1 - 6.6e-13 49.3 0.0 1.4e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG17183.1 - 1.4e-06 28.6 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG17183.1 - 2.5e-06 27.6 0.0 6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain RNA_pol_Rbc25 PF08292.12 OAG17183.1 - 0.046 13.9 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Abhydrolase_3 PF07859.13 OAG17184.1 - 4.2e-45 154.2 0.1 5.2e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 OAG17184.1 - 7.4e-05 21.9 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.28 OAG17184.1 - 0.0011 17.9 0.1 0.002 17.1 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Thioesterase PF00975.20 OAG17184.1 - 0.0073 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 OAG17184.1 - 0.012 15.2 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 OAG17184.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Aegerolysin PF06355.13 OAG17186.1 - 8.5e-48 161.7 3.2 9.5e-48 161.6 3.2 1.0 1 0 0 1 1 1 1 Aegerolysin SPOR PF05036.13 OAG17186.1 - 0.079 13.4 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation related domain ADH_zinc_N PF00107.26 OAG17188.1 - 8.8e-25 87.2 0.4 1.6e-24 86.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG17188.1 - 1.7e-17 63.3 0.3 2.9e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG17188.1 - 0.00024 20.4 0.1 0.00056 19.3 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG17188.1 - 0.00052 19.4 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.20 OAG17188.1 - 0.0018 17.6 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TrkA_N PF02254.18 OAG17188.1 - 0.003 17.8 0.1 0.0064 16.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain FdhD-NarQ PF02634.15 OAG17188.1 - 0.0037 17.0 0.1 0.018 14.7 0.1 1.9 1 1 0 1 1 1 1 FdhD/NarQ family Methyltransf_25 PF13649.6 OAG17188.1 - 0.024 15.3 0.1 0.054 14.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG17188.1 - 0.038 14.6 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.21 OAG17188.1 - 0.046 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family PglD_N PF17836.1 OAG17188.1 - 0.11 13.1 0.3 0.31 11.7 0.3 1.8 1 0 0 1 1 1 0 PglD N-terminal domain 3HCDH_N PF02737.18 OAG17188.1 - 0.17 11.8 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EthD PF07110.11 OAG17189.1 - 1e-14 55.4 0.2 1.3e-14 55.1 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG17189.1 - 0.015 15.8 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase TRI12 PF06609.13 OAG17190.1 - 8.3e-34 117.0 18.6 9.8e-34 116.7 18.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG17190.1 - 1.4e-21 76.8 41.7 1.4e-21 76.8 41.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17190.1 - 2.4e-07 30.0 9.2 2.4e-07 30.0 9.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter DUF373 PF04123.13 OAG17190.1 - 1.3 8.4 6.1 0.27 10.6 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) PhyH PF05721.13 OAG17192.1 - 2.2e-06 28.1 0.1 7.1e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_S15 PF02129.18 OAG17193.1 - 8.8e-38 130.4 0.1 7e-36 124.2 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG17193.1 - 4.6e-34 118.3 0.0 6.3e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF2190 PF09956.9 OAG17193.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) MFS_1 PF07690.16 OAG17194.1 - 1.8e-12 46.9 32.3 1.8e-12 46.9 32.3 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17194.1 - 3.2e-08 32.9 7.7 3.2e-08 32.9 7.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter PhyH PF05721.13 OAG17195.1 - 2.7e-10 40.9 0.0 2.4e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG17195.1 - 0.00018 20.4 0.6 0.8 8.4 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) FAD_binding_3 PF01494.19 OAG17196.1 - 2.4e-19 69.8 0.1 5e-19 68.7 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG17196.1 - 2.6e-07 30.6 0.9 2e-05 24.3 1.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG17196.1 - 4.2e-07 30.1 0.1 1.3e-06 28.6 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17196.1 - 7.1e-07 28.7 0.4 2.9e-05 23.5 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG17196.1 - 1.7e-06 27.2 0.9 0.0034 16.3 0.3 2.6 2 1 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 OAG17196.1 - 1.5e-05 24.3 0.6 2.7e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG17196.1 - 3e-05 23.4 0.1 5.1e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG17196.1 - 0.00023 20.3 0.6 0.0012 18.0 0.6 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG17196.1 - 0.00044 19.1 0.4 0.00092 18.0 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG17196.1 - 0.0011 18.9 1.0 0.01 15.8 0.5 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG17196.1 - 0.0014 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG17196.1 - 0.0058 15.9 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAG17196.1 - 0.011 14.8 0.6 0.017 14.2 0.6 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG17196.1 - 0.021 15.4 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG17196.1 - 0.029 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 OAG17196.1 - 0.1 11.4 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family Tau95 PF09734.9 OAG17196.1 - 0.15 12.9 0.0 1.7 9.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Fungal_trans PF04082.18 OAG17197.1 - 2.9e-06 26.5 0.8 6.7e-06 25.3 0.4 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17197.1 - 0.00067 19.7 3.6 0.00067 19.7 3.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG17197.1 - 0.016 15.6 0.8 0.016 15.6 0.8 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type PreAtp-grasp PF18604.1 OAG17197.1 - 0.16 11.6 0.3 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 Pre ATP-grasp domain GST_N_3 PF13417.6 OAG17198.1 - 1.4e-11 44.6 0.0 2.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG17198.1 - 1e-08 35.4 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG17198.1 - 1.9e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG17198.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 OAG17199.1 - 4.5e-21 75.7 0.0 1.4e-20 74.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.8 OAG17200.1 - 1.7e-23 82.9 0.2 1.7e-23 82.9 0.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) Baculo_F PF12259.8 OAG17200.1 - 0.31 9.5 0.4 0.34 9.4 0.4 1.2 1 0 0 1 1 1 0 Baculovirus F protein Pkinase PF00069.25 OAG17201.1 - 1.9e-36 125.8 0.0 9.4e-35 120.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG17201.1 - 1.8e-22 79.9 0.0 2.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YEATS PF03366.16 OAG17201.1 - 0.0026 17.7 0.5 0.005 16.8 0.5 1.4 1 0 0 1 1 1 1 YEATS family Kdo PF06293.14 OAG17201.1 - 0.082 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.26 OAG17204.1 - 1.4e-10 41.0 25.7 0.00014 22.1 0.7 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type NACHT PF05729.12 OAG17204.1 - 1.7e-06 28.1 0.1 7.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain zf-C2H2_4 PF13894.6 OAG17204.1 - 0.0017 19.0 24.0 0.093 13.6 1.2 6.0 5 0 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAG17204.1 - 0.0054 16.8 2.6 0.018 15.2 2.6 1.9 1 0 0 1 1 1 1 Zinc ribbon domain zf-met PF12874.7 OAG17204.1 - 0.0097 16.3 11.7 0.047 14.1 2.0 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OAG17204.1 - 0.011 16.2 22.1 0.27 11.7 0.2 6.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAG17204.1 - 0.042 13.6 11.1 0.37 10.6 0.2 4.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OAG17204.1 - 0.34 11.0 5.3 21 5.2 0.8 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG17204.1 - 0.6 10.5 10.6 0.54 10.6 1.4 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG17204.1 - 0.91 9.9 9.3 0.14 12.5 1.7 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OAG17204.1 - 5.3 6.9 7.4 20 5.1 0.8 3.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Drf_FH3 PF06367.16 OAG17205.1 - 0.016 14.8 0.7 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 Diaphanous FH3 Domain SNF2_N PF00176.23 OAG17206.1 - 1e-66 225.0 0.1 1.4e-66 224.7 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG17206.1 - 2.6e-13 50.3 0.0 6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG17206.1 - 6.7e-10 39.2 0.1 1.2e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG17206.1 - 2.5e-07 30.7 0.0 1e-06 28.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAG17206.1 - 4.4e-05 23.2 0.1 0.00016 21.4 0.1 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 OAG17206.1 - 0.0014 17.6 0.0 0.0028 16.6 0.0 1.4 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 NmrA PF05368.13 OAG17207.1 - 4.9e-15 55.7 0.0 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG17207.1 - 1e-14 54.9 0.0 1.6e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG17207.1 - 0.00039 20.7 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG17207.1 - 0.00044 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 OAG17207.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG17207.1 - 0.041 13.8 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 OAG17208.1 - 5.2e-11 43.6 0.7 6.4e-11 43.3 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAG17208.1 - 2.8e-10 40.1 0.9 1.9e-08 34.2 1.2 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAG17208.1 - 8.4e-08 31.8 1.2 1.5e-07 30.9 1.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG17208.1 - 8.5e-07 28.7 0.2 6.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG17208.1 - 0.00023 20.9 0.2 0.00049 19.8 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 OAG17208.1 - 0.00024 19.9 0.3 0.00044 19.0 0.3 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 OAG17208.1 - 0.00081 18.9 0.7 0.0011 18.5 0.7 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S15 PF02129.18 OAG17208.1 - 0.00085 19.0 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 OAG17208.1 - 0.016 15.1 0.1 0.072 12.9 0.1 2.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Epimerase PF01370.21 OAG17209.1 - 0.0037 16.8 0.0 0.0087 15.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG17209.1 - 0.0069 16.3 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG17209.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 OAG17209.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAG17209.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PEP_mutase PF13714.6 OAG17211.1 - 1.4e-09 37.8 0.0 1.6e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEP_mutase PF13714.6 OAG17212.1 - 3.2e-22 79.2 0.0 3.4e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG17212.1 - 1.8e-05 23.5 0.1 2.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.16 OAG17213.1 - 2.9e-15 56.1 10.3 1.4e-12 47.3 2.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17213.1 - 1.9e-07 30.3 3.9 4.1e-07 29.2 3.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG17213.1 - 0.0028 16.6 2.0 0.0071 15.3 0.1 2.0 2 0 0 2 2 2 1 MFS_1 like family LRRNT_2 PF08263.12 OAG17215.1 - 0.035 14.4 0.3 0.035 14.4 0.3 2.9 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain EspB PF05802.11 OAG17215.1 - 0.097 12.7 0.8 0.17 11.9 0.8 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein Lamprin PF06403.11 OAG17215.1 - 0.36 10.8 4.1 0.84 9.6 4.1 1.7 1 1 0 1 1 1 0 Lamprin NACHT PF05729.12 OAG17216.1 - 1e-07 32.0 0.5 8.8e-07 29.0 0.2 2.8 2 1 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 OAG17216.1 - 0.00026 20.4 1.1 0.00026 20.4 1.1 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins ABC_tran PF00005.27 OAG17216.1 - 0.00045 20.8 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OAG17216.1 - 0.0005 20.5 1.0 0.0057 17.0 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG17216.1 - 0.0057 16.9 0.7 0.066 13.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG17216.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 OAG17216.1 - 0.019 14.9 0.2 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OAG17216.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Vip3A_N PF12495.8 OAG17216.1 - 0.14 12.1 0.3 4 7.3 0.0 2.4 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal AAA_18 PF13238.6 OAG17216.1 - 0.15 12.6 0.1 0.66 10.5 0.1 2.2 1 0 0 1 1 1 0 AAA domain CRIC_ras_sig PF10534.9 OAG17216.1 - 0.15 12.2 0.5 1.5 9.0 0.0 2.9 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras CorA PF01544.18 OAG17216.1 - 1.5 8.1 6.2 11 5.3 1.4 2.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TauD PF02668.16 OAG17218.1 - 1.1e-10 41.8 0.0 4.7e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HET PF06985.11 OAG17219.1 - 0.00038 20.8 0.1 0.003 17.9 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) T5orf172 PF10544.9 OAG17221.1 - 7.9e-13 48.8 1.0 1.8e-11 44.5 1.0 2.1 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG17221.1 - 1e-12 48.5 0.3 1.5e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Aldedh PF00171.22 OAG17222.1 - 2.6e-160 533.9 0.0 2.9e-160 533.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG17222.1 - 0.0087 15.5 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) adh_short PF00106.25 OAG17223.1 - 1.2e-29 103.2 0.0 2e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG17223.1 - 1.1e-19 71.0 0.0 1.8e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG17223.1 - 0.0018 18.2 0.1 0.0052 16.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG17223.1 - 0.005 16.3 0.2 0.008 15.7 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG17223.1 - 0.12 12.2 0.1 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_9 PF13454.6 OAG17223.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding adh_short_C2 PF13561.6 OAG17224.1 - 1.2e-49 169.0 0.0 1.5e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17224.1 - 2.2e-41 141.5 0.0 3.3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17224.1 - 4e-12 46.4 0.1 5.4e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Tex_YqgF PF16921.5 OAG17224.1 - 0.052 14.0 0.0 15 6.0 0.0 2.2 2 0 0 2 2 2 0 Tex protein YqgF-like domain Epimerase PF01370.21 OAG17224.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAG17225.1 - 8.7e-87 291.4 0.0 1.1e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG17225.1 - 3.8e-11 43.8 0.2 8.9e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMO-like PF00743.19 OAG17227.1 - 1.5e-12 46.7 0.2 1.5e-10 40.2 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG17227.1 - 2.7e-10 40.3 0.0 7.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG17227.1 - 0.00011 22.3 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAG17227.1 - 0.0023 17.6 0.0 0.11 12.0 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG17227.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 OAG17228.1 - 9e-20 70.8 0.0 3.7e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17228.1 - 1.4e-05 25.1 9.0 2.6e-05 24.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 OAG17229.1 - 1.2e-11 44.5 0.3 1.2e-11 44.5 0.3 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG17229.1 - 0.0069 15.2 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Bap31_Bap29_C PF18035.1 OAG17229.1 - 0.043 13.8 0.7 0.086 12.9 0.1 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain SET_assoc PF11767.8 OAG17229.1 - 0.12 12.0 0.2 0.39 10.4 0.2 1.9 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Fungal_TACC PF12709.7 OAG17229.1 - 1.1 9.8 2.8 6.2 7.3 0.2 2.4 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Amidohydro_3 PF07969.11 OAG17230.1 - 1.3e-68 232.6 0.1 1.7e-68 232.3 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG17230.1 - 1.5e-05 24.5 0.0 7.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Fels1 PF05666.11 OAG17230.1 - 0.23 11.1 1.4 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like NAS PF03059.16 OAG17231.1 - 6e-70 235.7 0.0 7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 OAG17231.1 - 2.9e-09 36.9 0.0 4.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GMC_oxred_N PF00732.19 OAG17233.1 - 3.7e-62 210.4 0.0 4.8e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG17233.1 - 2.3e-29 102.8 0.0 7.6e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG17233.1 - 5.5e-06 25.7 0.2 0.069 12.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG17233.1 - 3.8e-05 23.1 0.4 0.045 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG17233.1 - 4.1e-05 23.3 3.3 0.00062 19.4 3.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG17233.1 - 0.00041 19.7 0.4 0.5 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG17233.1 - 0.0032 16.6 0.1 0.0052 15.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG17233.1 - 0.0035 17.5 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG17233.1 - 0.036 12.8 0.3 0.51 9.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG17233.1 - 0.21 12.2 1.2 0.33 11.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eRF1_1 PF03463.15 OAG17234.1 - 3.5e-49 166.1 0.4 5.5e-49 165.4 0.4 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OAG17234.1 - 4.2e-18 65.9 0.0 7.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAG17234.1 - 8.3e-15 55.3 0.0 1.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF3667 PF12412.8 OAG17234.1 - 0.17 11.4 0.1 0.43 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) HET PF06985.11 OAG17235.1 - 1.3e-24 87.2 0.1 2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_rhamnosid6H PF17389.2 OAG17236.1 - 2.6e-17 63.1 2.6 3.3e-15 56.2 1.5 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 OAG17236.1 - 9.4e-06 25.3 0.1 2.6e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 OAG17236.1 - 0.053 13.5 0.5 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain NUDIX PF00293.28 OAG17237.1 - 6.2e-07 29.5 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 OAG17238.1 - 1.8e-127 425.1 3.3 2.1e-127 424.9 3.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAG17238.1 - 2.3e-15 56.8 0.1 1.8e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 OAG17238.1 - 5.5e-07 29.3 1.7 0.0031 17.0 1.7 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAG17238.1 - 1.6e-05 24.1 0.6 4.1e-05 22.8 0.3 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAG17238.1 - 0.0041 16.6 4.9 0.0063 16.0 2.1 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein YpsA PF06908.11 OAG17238.1 - 0.0071 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family ThiG PF05690.14 OAG17238.1 - 0.017 14.4 1.6 0.018 14.3 0.4 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NanE PF04131.14 OAG17238.1 - 0.02 14.1 0.2 0.042 13.0 0.2 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 OAG17238.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain RasGAP PF00616.19 OAG17239.1 - 8e-52 176.0 0.0 2.2e-51 174.5 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAG17239.1 - 2.4e-47 160.5 2.9 2.4e-47 160.5 2.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus CH PF00307.31 OAG17239.1 - 4.5e-10 39.7 0.0 1.7e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 OAG17239.1 - 3.3e-09 35.7 57.8 0.49 10.3 0.1 14.9 16 0 0 16 16 16 6 IQ calmodulin-binding motif Trypan_PARP PF05887.11 OAG17239.1 - 0.016 15.2 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CAMSAP_CH PF11971.8 OAG17239.1 - 0.1 12.4 0.0 7.8 6.4 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain DMA PF03474.14 OAG17240.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif HeLo PF14479.6 OAG17241.1 - 5.1e-36 124.5 0.4 4e-35 121.5 0.4 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 OAG17241.1 - 3e-09 37.0 0.4 1.1e-08 35.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG17241.1 - 0.0014 18.9 0.0 0.0098 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG17241.1 - 0.0026 18.2 0.0 0.013 15.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG17241.1 - 0.0086 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG17241.1 - 0.014 15.9 0.0 0.052 14.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 OAG17241.1 - 0.03 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAG17241.1 - 0.034 14.5 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAG17241.1 - 0.039 13.1 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 OAG17241.1 - 0.063 13.8 0.0 0.27 11.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OAG17241.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG17241.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sugar_tr PF00083.24 OAG17242.1 - 4.1e-33 114.9 23.6 1.1e-31 110.2 23.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17242.1 - 1.6e-30 106.2 27.6 1.6e-30 106.2 27.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1156 PF06634.12 OAG17242.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Sod_Fe_N PF00081.22 OAG17244.1 - 0.03 14.8 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribonucleas_3_3 PF14622.6 OAG17245.1 - 2.3e-09 37.5 0.0 4.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG17245.1 - 1.4e-07 32.1 0.0 5e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Mucin PF01456.17 OAG17245.1 - 0.22 11.5 14.2 0.38 10.7 14.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 OAG17245.1 - 0.41 10.6 11.2 0.8 9.7 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CFEM PF05730.11 OAG17246.1 - 1.6e-11 44.1 13.4 3.1e-11 43.2 13.4 1.5 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.11 OAG17246.1 - 0.047 12.0 13.8 0.05 11.9 13.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC14 PF15254.6 OAG17246.1 - 1.8 7.2 10.0 2.1 6.9 10.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 MFS_1 PF07690.16 OAG17247.1 - 1.4e-34 119.6 27.4 2.4e-34 118.8 27.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17247.1 - 7.8e-09 34.9 7.7 7.8e-09 34.9 7.7 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter Cytochrom_B558a PF05038.13 OAG17247.1 - 0.059 12.9 1.1 0.34 10.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit MFS_2 PF13347.6 OAG17247.1 - 3.5 6.1 27.6 0.091 11.3 2.5 3.5 2 2 1 3 3 3 0 MFS/sugar transport protein adh_short_C2 PF13561.6 OAG17248.1 - 2.6e-53 181.0 0.2 3.2e-53 180.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17248.1 - 4.6e-38 130.6 1.9 6.3e-38 130.2 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17248.1 - 3e-12 46.8 0.2 4e-12 46.4 0.2 1.1 1 0 0 1 1 1 1 KR domain QRPTase_C PF01729.19 OAG17248.1 - 0.032 14.0 0.1 0.14 11.9 0.1 2.1 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Ribonucleas_3_3 PF14622.6 OAG17249.1 - 1.2e-13 51.3 0.0 1.7e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG17249.1 - 5.4e-10 39.8 0.0 3.8e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain cNMPbd_u2 PF16643.5 OAG17252.1 - 2.6e-46 158.0 13.9 2.6e-46 158.0 13.9 1.8 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 OAG17252.1 - 1e-32 112.0 0.0 2.7e-18 65.8 0.0 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 OAG17252.1 - 2.4e-10 39.6 5.3 1 9.6 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 OAG17252.1 - 5.8e-08 32.9 0.1 0.064 13.7 0.1 5.8 2 1 6 8 8 8 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG17252.1 - 0.00016 21.8 3.8 79 4.4 0.0 7.1 7 1 0 7 7 7 0 Leucine Rich Repeat F-box-like PF12937.7 OAG17252.1 - 0.00035 20.4 0.1 0.0019 18.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG17252.1 - 0.00053 19.8 4.0 0.0018 18.1 0.1 3.1 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 OAG17252.1 - 0.0038 16.9 0.0 2.9 7.7 0.2 3.1 2 1 0 2 2 2 2 Leucine rich repeat SNF2_N PF00176.23 OAG17253.1 - 6.9e-52 176.3 0.0 1.2e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG17253.1 - 7e-20 71.4 0.0 3.3e-17 62.8 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 OAG17253.1 - 3.3e-17 62.4 1.0 1e-16 60.7 0.1 2.4 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.15 OAG17253.1 - 1.3e-08 35.0 0.0 3.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG17253.1 - 4.6e-05 22.7 0.1 0.00011 21.5 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RNase_PH PF01138.21 OAG17254.1 - 6.7e-36 123.7 0.0 1.2e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG17254.1 - 0.0091 16.0 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glyco_hydro_3 PF00933.21 OAG17257.1 - 1.7e-46 159.1 0.0 2.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG17257.1 - 1.6e-07 31.5 0.0 2.4e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain SAP PF02037.27 OAG17258.1 - 0.06 13.1 0.2 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 SAP domain GMC_oxred_N PF00732.19 OAG17260.1 - 2.1e-66 224.3 0.0 3.3e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG17260.1 - 1.4e-33 116.5 0.1 2.6e-33 115.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG17260.1 - 2.1e-07 30.4 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG17260.1 - 4.9e-06 26.4 0.2 0.095 12.3 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG17260.1 - 0.0018 17.6 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG17260.1 - 0.0045 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG17260.1 - 0.035 14.7 0.2 3.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG17260.1 - 0.062 12.4 0.1 0.093 11.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ubiquitin PF00240.23 OAG17262.1 - 1.1e-14 53.9 0.6 1.7e-14 53.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG17262.1 - 7.5e-08 32.1 0.5 1.4e-07 31.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG17262.1 - 0.02 15.2 0.4 0.037 14.4 0.4 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 OAG17262.1 - 0.022 15.2 0.1 0.061 13.8 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OAG17262.1 - 0.15 12.7 0.5 0.38 11.4 0.4 1.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAG17262.1 - 1.4 9.0 3.9 0.6 10.2 0.4 2.2 2 1 1 3 3 3 0 Ubiquitin-like domain ENTH PF01417.20 OAG17264.1 - 1.3e-46 157.7 0.3 1.7e-46 157.3 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAG17264.1 - 0.00077 18.5 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 OAG17264.1 - 0.065 13.3 10.4 0.15 12.1 1.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5102) VHS PF00790.19 OAG17264.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.21 OAG17265.1 - 3.3e-41 141.2 0.2 4.2e-41 140.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-Paramyx-P PF13008.7 OAG17266.1 - 8.4 5.9 10.5 1.3 8.6 4.9 2.1 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Cys_Met_Meta_PP PF01053.20 OAG17267.1 - 3.9e-59 200.1 0.0 1.2e-58 198.5 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG17267.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Pro_dh PF01619.18 OAG17268.1 - 2.1e-57 194.9 0.2 2.8e-57 194.5 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase TP_methylase PF00590.20 OAG17268.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L14 PF00238.19 OAG17270.1 - 3.6e-33 114.3 0.0 4.3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Glyco_hydro_1 PF00232.18 OAG17271.1 - 2.3e-71 240.6 0.8 8.2e-36 123.4 0.2 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 FMN_dh PF01070.18 OAG17272.1 - 1.1e-126 422.6 0.0 1.3e-126 422.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG17272.1 - 3.7e-10 39.3 0.1 5.7e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG17272.1 - 1.1e-06 28.1 0.1 1.8e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG17272.1 - 0.0012 18.3 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 OAG17272.1 - 0.0012 18.3 1.6 0.0021 17.5 1.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 OAG17272.1 - 0.013 14.9 0.1 0.24 10.7 0.1 2.4 2 1 1 3 3 3 0 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 OAG17272.1 - 0.033 13.5 0.3 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 OAG17272.1 - 0.13 11.4 0.1 0.44 9.7 0.0 1.8 2 1 0 2 2 2 0 Dihydroorotate dehydrogenase Piwi PF02171.17 OAG17273.1 - 7.4e-69 232.3 0.0 6e-68 229.3 0.0 1.9 2 0 0 2 2 2 1 Piwi domain DUF1993 PF09351.10 OAG17274.1 - 1.3e-45 155.5 0.0 1.4e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) CpeT PF06206.11 OAG17274.1 - 0.0025 17.8 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) APG5 PF04106.12 OAG17274.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg5 Glyco_hydro_76 PF03663.14 OAG17275.1 - 2.8e-44 152.2 1.7 3.5e-44 151.8 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG17275.1 - 0.003 16.7 0.5 0.083 12.0 0.0 2.4 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Fungal_trans_2 PF11951.8 OAG17276.1 - 4.6e-36 124.4 0.0 6.5e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17276.1 - 1.3e-07 31.6 9.3 2.1e-07 31.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.20 OAG17276.1 - 0.066 13.1 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein MFS_1 PF07690.16 OAG17277.1 - 1.7e-41 142.3 51.7 1.9e-40 138.9 51.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily ATP-synt_8 PF00895.20 OAG17277.1 - 2.4 8.7 4.4 12 6.4 0.0 3.5 3 0 0 3 3 3 0 ATP synthase protein 8 Trp_oprn_chp PF09534.10 OAG17277.1 - 5.9 6.6 8.6 1.2 8.9 0.3 3.3 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pribosyltran PF00156.27 OAG17278.1 - 1.5e-21 76.6 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P-mevalo_kinase PF04275.14 OAG17278.1 - 3e-21 75.5 0.0 5.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 OAG17278.1 - 1.6e-14 53.8 1.5 3.7e-14 52.6 1.5 1.7 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.6 OAG17278.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPRTase PF14681.6 OAG17278.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_12 PF08242.12 OAG17278.1 - 0.022 15.5 0.0 0.17 12.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain PRTase_2 PF15609.6 OAG17278.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase TPPII_N PF12583.8 OAG17279.1 - 0.8 10.3 4.6 7.6 7.1 0.2 2.1 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal HET PF06985.11 OAG17280.1 - 2.2e-26 93.0 0.8 4.3e-26 92.0 0.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CitG PF01874.16 OAG17281.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Aldolase_II PF00596.21 OAG17282.1 - 1.8e-47 161.7 0.2 2.5e-47 161.2 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sugar_tr PF00083.24 OAG17283.1 - 5e-65 220.1 13.4 6e-65 219.9 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17283.1 - 1.6e-10 40.5 35.2 6.5e-07 28.6 15.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3852 PF12963.7 OAG17283.1 - 0.93 9.9 3.4 0.32 11.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Phage_CI_repr PF07022.13 OAG17284.1 - 0.011 15.8 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain p450 PF00067.22 OAG17285.1 - 5.4e-64 216.6 0.0 6.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG17286.1 - 9.7e-17 60.9 50.2 4e-15 55.6 49.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily IBR PF01485.21 OAG17287.1 - 4.2e-18 65.3 23.9 3.8e-11 43.0 4.2 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAG17287.1 - 0.00093 19.0 1.3 0.00093 19.0 1.3 4.4 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG17287.1 - 0.0099 16.2 5.2 0.0099 16.2 5.2 4.0 3 2 1 4 4 4 1 Ring finger domain OrfB_Zn_ribbon PF07282.11 OAG17287.1 - 0.027 14.4 4.4 0.027 14.4 4.4 3.7 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Stc1 PF12898.7 OAG17287.1 - 0.11 13.1 0.4 0.11 13.1 0.4 3.4 2 1 1 3 3 3 0 Stc1 domain Nop16 PF09420.10 OAG17288.1 - 4.8e-63 213.0 10.6 5.5e-63 212.8 10.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Toxin_YhaV PF11663.8 OAG17288.1 - 0.0036 17.3 0.5 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Toxin with endonuclease activity, of toxin-antitoxin system Zip PF02535.22 OAG17289.1 - 1.4e-56 192.1 12.2 7e-56 189.8 12.2 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_Dp1 PF16938.5 OAG17289.1 - 0.28 11.4 2.2 0.85 9.9 0.3 2.5 2 0 0 2 2 2 0 Putative phage holin Dp-1 Ndc1_Nup PF09531.10 OAG17291.1 - 0.065 11.9 0.1 0.074 11.7 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_trans_2_3 PF13632.6 OAG17293.1 - 1e-09 38.6 5.1 2.9e-09 37.1 5.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG17293.1 - 2.6e-09 37.3 0.3 4.5e-09 36.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 OAG17293.1 - 5.2e-09 35.3 3.8 1.1e-07 30.8 3.5 2.2 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.6 OAG17293.1 - 6.9e-07 28.9 0.7 2e-06 27.4 0.7 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 GST_C_4 PF14834.6 OAG17293.1 - 0.0075 16.7 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ntox44 PF15607.6 OAG17293.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 44 Acyl_transf_3 PF01757.22 OAG17294.1 - 2.3e-31 109.1 29.6 2.7e-31 108.9 29.6 1.1 1 0 0 1 1 1 1 Acyltransferase family PIG-P PF08510.12 OAG17294.1 - 0.23 11.4 8.7 0.063 13.2 3.7 2.4 2 0 0 2 2 2 0 PIG-P Acetyltransf_3 PF13302.7 OAG17295.1 - 3.7e-18 66.5 0.0 5.1e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FMO-like PF00743.19 OAG17296.1 - 5.3e-15 54.8 0.7 7.7e-12 44.4 0.2 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG17296.1 - 1.4e-13 50.8 0.1 4.1e-12 46.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG17296.1 - 3.2e-09 36.9 0.0 1.1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17296.1 - 9.7e-09 34.9 0.0 7.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG17296.1 - 2.1e-06 27.2 0.0 0.0033 16.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG17296.1 - 0.00063 19.8 0.1 0.43 10.5 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG17296.1 - 0.0092 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG17296.1 - 0.016 14.8 0.0 0.51 9.9 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 OAG17296.1 - 0.023 13.8 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG17296.1 - 0.035 12.8 0.0 0.7 8.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 OAG17296.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Sugar_tr PF00083.24 OAG17297.1 - 8.2e-82 275.5 25.4 1e-81 275.2 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17297.1 - 4.3e-11 42.3 29.1 4.3e-11 42.3 29.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 OAG17298.1 - 4.4e-62 210.2 0.6 5.6e-62 209.9 0.6 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG17298.1 - 0.00037 20.7 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 OAG17298.1 - 0.017 13.7 0.0 0.03 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) zf-PARP PF00645.18 OAG17299.1 - 0.15 12.9 0.5 0.28 12.1 0.5 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HET PF06985.11 OAG17300.1 - 3.8e-06 27.3 0.1 4.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RloB PF13707.6 OAG17302.1 - 0.11 12.6 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 RloB-like protein ABM PF03992.16 OAG17303.1 - 2.1e-05 24.6 0.0 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase MFS_2 PF13347.6 OAG17304.1 - 0.11 11.0 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein adh_short_C2 PF13561.6 OAG17305.1 - 3.5e-37 128.2 0.8 8.2e-37 127.0 0.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17305.1 - 2.1e-33 115.4 1.8 3.5e-33 114.7 1.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17305.1 - 2.8e-06 27.3 0.3 2.8e-06 27.3 0.3 1.7 2 0 0 2 2 2 1 KR domain NAD_Gly3P_dh_N PF01210.23 OAG17305.1 - 0.025 14.6 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 OAG17305.1 - 0.045 13.6 0.5 0.064 13.1 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAG17305.1 - 0.067 13.1 0.3 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG17305.1 - 0.13 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.27 OAG17305.1 - 0.13 12.9 0.6 0.3 11.7 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phage_spike_2 PF18781.1 OAG17306.1 - 0.018 15.1 0.1 6.4 6.9 0.0 2.2 1 1 1 2 2 2 0 Phage spike trimer DUF5345 PF17280.2 OAG17306.1 - 1 9.3 3.1 6.4 6.8 0.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5345) DUF3328 PF11807.8 OAG17307.1 - 3e-32 112.2 0.4 3.9e-32 111.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.18 OAG17308.1 - 3.4e-22 78.8 0.0 5.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17308.1 - 1.2e-08 34.9 8.1 2.4e-08 33.9 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldh_1_N PF00056.23 OAG17309.1 - 1.8e-31 109.1 0.1 2.9e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG17309.1 - 4.2e-22 78.8 0.0 5.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 OAG17309.1 - 0.0009 19.8 0.3 0.003 18.1 0.3 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG17309.1 - 0.0011 18.6 0.1 0.0053 16.4 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OAG17309.1 - 0.0032 17.7 0.1 0.11 12.7 0.1 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 OAG17309.1 - 0.027 14.1 1.0 0.22 11.1 0.2 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase zf-C3HC4_3 PF13920.6 OAG17310.1 - 8.5e-10 38.3 7.5 1.6e-09 37.5 7.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG17310.1 - 4.9e-08 32.8 7.3 7.6e-08 32.2 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG17310.1 - 1.6e-07 31.0 8.3 1.6e-06 27.9 8.3 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAG17310.1 - 2.8e-07 30.7 7.1 5.4e-07 29.8 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG17310.1 - 4.5e-07 29.6 7.3 8.1e-07 28.8 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG17310.1 - 5.9e-06 26.2 1.5 5.9e-06 26.2 1.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG17310.1 - 3.7e-05 23.5 11.9 0.00096 18.9 12.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG17310.1 - 0.0086 16.2 5.3 0.053 13.7 5.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING NPR3 PF03666.13 OAG17310.1 - 0.039 12.8 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-rbx1 PF12678.7 OAG17310.1 - 0.053 13.8 4.5 0.12 12.7 4.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG17310.1 - 0.12 12.2 4.4 0.28 11.0 4.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 OAG17310.1 - 0.23 11.5 6.9 0.32 11.0 1.4 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_11 PF17123.5 OAG17310.1 - 6.3 6.6 9.7 9.8 6.0 6.6 2.5 2 1 0 2 2 2 0 RING-like zinc finger DNApol_Exo PF18136.1 OAG17311.1 - 2.3e-103 345.2 2.2 3.9e-103 344.5 0.0 2.1 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAG17311.1 - 1.7e-57 195.2 0.2 7.7e-57 193.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 OAG17311.1 - 0.015 15.0 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease Uds1 PF15456.6 OAG17311.1 - 0.071 13.3 3.1 0.21 11.8 3.1 1.8 1 0 0 1 1 1 0 Up-regulated During Septation HET PF06985.11 OAG17312.1 - 3.9e-20 72.7 0.2 5.1e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 OAG17317.1 - 2.6e-14 54.4 0.9 6.6e-14 53.0 0.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG17317.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 OAG17318.1 - 3.5e-29 102.2 0.0 5.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG17318.1 - 1.4e-08 34.3 0.0 5.3e-06 25.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG17318.1 - 2.3e-06 27.2 0.9 0.0076 15.6 0.0 2.9 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG17318.1 - 3.3e-06 26.4 0.4 0.048 12.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG17318.1 - 3.9e-06 27.0 0.1 1.2e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17318.1 - 5e-05 22.7 0.1 0.0005 19.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG17318.1 - 9.6e-05 21.2 0.8 0.00086 18.1 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG17318.1 - 0.00017 20.8 0.7 0.00032 19.9 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG17318.1 - 0.00027 19.9 0.0 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 OAG17318.1 - 0.0008 19.1 0.3 0.0023 17.6 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG17318.1 - 0.0012 18.0 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 OAG17318.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAG17318.1 - 0.029 14.9 0.9 0.16 12.5 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG17318.1 - 0.064 12.3 1.7 0.093 11.8 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG17318.1 - 0.079 12.9 0.5 11 6.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG17318.1 - 0.085 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG17318.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAG17318.1 - 0.11 11.8 0.8 0.19 11.0 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase SET PF00856.28 OAG17319.1 - 4.2e-13 50.0 0.0 9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 SET domain Nucleocapsid-N PF11030.8 OAG17320.1 - 0.055 13.4 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid protein N AhpC-TSA_2 PF13911.6 OAG17321.1 - 2.5e-23 82.4 0.0 4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3892 PF13031.6 OAG17321.1 - 0.022 15.3 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) AhpC-TSA PF00578.21 OAG17321.1 - 0.06 13.3 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 AhpC/TSA family ADH_N PF08240.12 OAG17322.1 - 4.9e-26 90.8 1.7 1.3e-25 89.4 1.7 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG17322.1 - 9e-20 71.0 0.3 1.7e-19 70.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG17322.1 - 0.00011 22.5 0.1 0.00019 21.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 OAG17322.1 - 0.00021 20.8 0.0 0.001 18.6 0.0 2.1 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG17322.1 - 0.0003 20.2 1.4 0.00051 19.4 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG17322.1 - 0.017 16.2 0.0 0.036 15.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG17322.1 - 0.021 14.4 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pep_deformylase PF01327.21 OAG17322.1 - 0.022 14.3 0.0 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 Polypeptide deformylase TrkA_N PF02254.18 OAG17322.1 - 0.062 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_18 PF00704.28 OAG17325.1 - 1.8e-52 179.0 0.7 2.2e-52 178.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG17325.1 - 1.8e-08 34.7 38.8 5.6e-05 23.5 16.7 2.9 2 0 0 2 2 2 2 Chitin recognition protein FAM194 PF14977.6 OAG17329.1 - 0.23 10.8 0.7 7.6 5.8 0.2 2.0 1 1 1 2 2 2 0 FAM194 protein Egh16-like PF11327.8 OAG17330.1 - 4.7e-59 199.9 13.9 5.9e-59 199.6 13.9 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 OAG17330.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain HemeBinding_Shp PF11545.8 OAG17330.1 - 0.11 12.5 2.6 0.088 12.8 0.6 1.7 1 1 1 2 2 2 0 Cell surface heme-binding protein Shp Amidase PF01425.21 OAG17331.1 - 1.6e-89 301.0 0.7 1.9e-89 300.7 0.7 1.1 1 0 0 1 1 1 1 Amidase DUF1201 PF06716.11 OAG17332.1 - 0.093 12.8 2.9 2.2 8.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) DUF4648 PF15505.6 OAG17333.1 - 0.052 14.4 0.9 0.074 13.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) CFEM PF05730.11 OAG17334.1 - 2.3e-07 30.8 11.1 4.2e-07 30.0 11.1 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 OAG17334.1 - 0.0063 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG17334.1 - 0.03 14.4 7.2 0.046 13.8 5.7 2.0 1 1 2 3 3 3 0 Podoplanin DUF1935 PF09149.10 OAG17334.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) FSA_C PF10479.9 OAG17334.1 - 0.76 7.8 12.4 0.97 7.5 12.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HicA_toxin PF07927.12 OAG17335.1 - 0.15 12.1 0.2 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, HET PF06985.11 OAG17336.1 - 4.1e-23 82.4 0.0 1.4e-22 80.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) polyprenyl_synt PF00348.17 OAG17337.1 - 7.5e-39 133.3 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Methyltransf_2 PF00891.18 OAG17337.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 OAG17338.1 - 4e-63 213.8 0.0 4.9e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_38 PF13936.6 OAG17339.1 - 0.073 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cupin_2 PF07883.11 OAG17340.1 - 1.6e-13 50.1 0.5 5.4e-07 29.2 0.2 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG17340.1 - 1.5e-07 31.4 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG17340.1 - 1.6e-05 24.5 0.0 0.0027 17.4 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF861) Cupin_4 PF08007.12 OAG17340.1 - 0.00036 20.1 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein CENP-C_C PF11699.8 OAG17340.1 - 0.00071 19.7 0.1 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 OAG17340.1 - 0.011 15.6 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 OAG17340.1 - 0.019 14.6 0.2 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 Cupin EutQ PF06249.12 OAG17340.1 - 0.066 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ AraC_binding_2 PF14525.6 OAG17340.1 - 0.17 11.5 0.0 21 4.8 0.0 2.2 2 0 0 2 2 2 0 AraC-binding-like domain p450 PF00067.22 OAG17341.1 - 5.7e-54 183.6 0.0 7.5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG17342.1 - 1.9e-13 50.1 4.9 1.9e-13 50.1 4.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17342.1 - 1.7e-10 40.8 7.7 4e-10 39.6 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1810 PF08837.11 OAG17342.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) p450 PF00067.22 OAG17343.1 - 8.8e-64 215.9 0.0 1.1e-63 215.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG17345.1 - 9.3e-81 272.0 24.1 1.1e-80 271.8 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17345.1 - 5.1e-25 88.1 31.2 2.8e-21 75.9 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG17345.1 - 5.3e-06 25.1 3.1 1.3e-05 23.9 3.1 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG17345.1 - 0.0097 14.2 0.5 0.0097 14.2 0.5 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 OAG17346.1 - 6e-13 48.8 3.0 7.3e-10 38.6 0.4 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG17346.1 - 1.2e-10 41.2 0.2 0.00026 20.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG17346.1 - 5e-05 22.6 0.0 9.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG17346.1 - 0.00059 18.7 0.1 0.074 11.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 OAG17346.1 - 0.00075 19.7 0.1 0.0047 17.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG17346.1 - 0.0052 16.4 0.4 0.1 12.2 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG17346.1 - 0.0092 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG17346.1 - 0.0092 14.9 1.2 0.092 11.6 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG17346.1 - 0.017 15.7 0.3 10 6.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG17346.1 - 0.042 12.9 1.0 0.096 11.8 1.0 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG17346.1 - 0.047 12.9 0.5 0.36 10.0 0.5 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG17346.1 - 0.052 12.6 0.6 0.23 10.5 0.6 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 OAG17347.1 - 7e-24 84.4 2.1 1.1e-19 70.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG17347.1 - 9.7e-16 58.0 0.1 5.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG17347.1 - 5.5e-06 26.4 0.2 7.6e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG17347.1 - 0.00035 19.8 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein QRPTase_C PF01729.19 OAG17347.1 - 0.027 14.2 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ApoLp-III PF07464.11 OAG17347.1 - 0.03 14.4 0.2 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MnmE_helical PF12631.7 OAG17347.1 - 0.051 13.7 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 MnmE helical domain Sacchrp_dh_NADP PF03435.18 OAG17347.1 - 0.081 13.2 0.0 0.22 11.8 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG17347.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TPR_12 PF13424.6 OAG17348.1 - 1.1e-37 128.2 12.9 5.5e-11 42.6 0.2 4.8 1 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG17348.1 - 4.2e-36 121.8 7.3 1.7e-08 34.0 0.2 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG17348.1 - 6e-16 57.5 1.4 0.045 13.6 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.14 OAG17348.1 - 1.3e-14 53.2 2.6 0.012 16.2 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG17348.1 - 3.4e-10 39.2 4.8 0.25 11.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG17348.1 - 2e-09 36.8 2.1 1.4 9.1 0.2 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG17348.1 - 1.3e-07 31.3 0.5 1.5 9.3 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG17348.1 - 5.8e-07 29.9 0.1 0.085 13.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG17348.1 - 1.3e-06 28.0 8.9 3e-05 23.6 7.0 2.4 1 1 1 2 2 2 1 MalT-like TPR region TPR_17 PF13431.6 OAG17348.1 - 3.2e-05 24.0 1.9 3.7 8.1 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG17348.1 - 7.1e-05 23.4 1.7 0.91 10.2 0.4 4.1 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17348.1 - 0.00019 22.0 3.6 0.62 11.0 0.4 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF615 PF04751.14 OAG17348.1 - 0.027 14.4 0.1 0.084 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF615) MIT PF04212.18 OAG17348.1 - 0.14 12.2 0.1 1.4 9.0 0.1 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SesA PF17107.5 OAG17348.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 OAG17350.1 - 4.5e-43 144.0 7.7 1.1e-06 28.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG17350.1 - 1.4e-40 137.5 13.3 3.1e-12 46.6 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG17350.1 - 2.4e-13 49.2 6.0 0.0014 18.4 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG17350.1 - 2.2e-12 46.1 9.4 0.01 15.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG17350.1 - 5.9e-08 32.2 9.7 0.0023 17.9 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG17350.1 - 2.4e-06 27.3 1.8 0.081 13.2 0.0 5.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17350.1 - 9.3e-06 26.1 2.2 23 6.2 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG17350.1 - 1e-05 26.1 2.8 2.1 9.1 0.1 5.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG17350.1 - 1.2e-05 25.5 2.7 10 7.1 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.12 OAG17350.1 - 1.3e-05 25.2 0.0 3.6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 OAG17350.1 - 1.4e-05 24.4 0.0 3.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAG17350.1 - 0.0015 18.8 0.5 0.022 15.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain TPR_17 PF13431.6 OAG17350.1 - 0.021 15.2 0.0 52 4.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG17350.1 - 0.075 13.6 2.1 18 5.9 0.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5626 PF18540.1 OAG17350.1 - 0.13 12.8 0.2 0.31 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5626) TPR_6 PF13174.6 OAG17350.1 - 0.57 10.9 3.7 23 5.9 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Acetyltransf_2 PF00797.17 OAG17353.1 - 8.9e-30 104.2 0.0 1.9e-29 103.2 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 OAG17353.1 - 0.0007 20.0 0.5 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily Pkinase PF00069.25 OAG17357.1 - 6.5e-07 29.0 0.0 0.00024 20.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG17357.1 - 0.013 14.8 0.0 0.15 11.3 0.0 2.6 2 1 0 2 2 2 0 Protein tyrosine kinase DUF1828 PF08861.10 OAG17357.1 - 0.16 12.2 0.1 6 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF1828 p450 PF00067.22 OAG17358.1 - 7.2e-49 166.8 0.0 8.8e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 OAG17359.1 - 5.1e-27 94.6 0.0 1.7e-18 66.6 0.0 2.9 2 1 0 2 2 2 2 Transferase family adh_short_C2 PF13561.6 OAG17360.1 - 1.2e-55 188.7 0.0 1.4e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17360.1 - 1.4e-42 145.4 0.1 1.6e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17360.1 - 1.8e-13 50.8 0.3 3.8e-13 49.8 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG17360.1 - 0.00093 18.7 0.1 0.0013 18.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rep_1B PF17873.1 OAG17360.1 - 0.076 12.9 1.8 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Replicase polyprotein 1ab GDP_Man_Dehyd PF16363.5 OAG17360.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 OAG17361.1 - 8.6e-68 229.2 0.0 1e-67 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRAM_LAG1_CLN8 PF03798.16 OAG17362.1 - 6.1e-37 127.3 23.9 1.2e-36 126.3 23.9 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 OAG17362.1 - 5.1e-21 74.1 0.0 1.2e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein VPS38 PF17649.1 OAG17363.1 - 2.1e-16 59.8 0.0 1.1e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 Atg14 PF10186.9 OAG17363.1 - 9.1e-15 54.5 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ARGLU PF15346.6 OAG17363.1 - 0.19 11.6 7.4 0.31 10.9 7.4 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 TPR_MLP1_2 PF07926.12 OAG17363.1 - 0.54 10.3 5.0 0.44 10.6 3.7 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mhr1 PF12829.7 OAG17364.1 - 2.2e-29 101.4 0.0 5.5e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination IFN-gamma PF00714.17 OAG17364.1 - 0.0046 16.8 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Interferon gamma Exonuc_VII_L PF02601.15 OAG17364.1 - 3 7.3 13.7 2.1 7.8 11.2 2.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit Atg14 PF10186.9 OAG17364.1 - 6.7 5.7 9.6 11 4.9 9.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 OAG17364.1 - 8.3 6.9 10.0 16 5.9 10.0 1.5 1 0 0 1 1 1 0 AAA domain GFA PF04828.14 OAG17365.1 - 1.8e-18 66.6 0.2 3.4e-18 65.8 0.2 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2703 PF10865.8 OAG17365.1 - 1 9.5 4.6 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) DUF4710 PF15828.5 OAG17367.1 - 7.7 6.7 8.1 17 5.7 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) FAD_binding_4 PF01565.23 OAG17368.1 - 1e-14 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG17368.1 - 0.00028 20.9 0.2 0.0009 19.3 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.19 OAG17369.1 - 4.2e-57 193.8 0.0 5.4e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG17369.1 - 9.1e-36 123.5 0.1 1.5e-35 122.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG17369.1 - 4.8e-07 29.2 0.5 1.3e-06 27.7 0.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAG17369.1 - 8.7e-07 28.8 5.0 0.00012 21.9 3.8 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG17369.1 - 1.1e-05 25.6 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17369.1 - 9.6e-05 21.7 0.2 0.0053 16.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG17369.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG17369.1 - 0.0012 18.0 0.9 0.032 13.3 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 OAG17369.1 - 0.0024 17.2 1.2 0.0054 16.0 0.4 1.8 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 OAG17369.1 - 0.0094 14.5 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 OAG17369.1 - 0.1 11.4 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 OAG17369.1 - 0.13 11.3 1.3 9.9 5.1 0.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG17369.1 - 0.18 11.0 0.5 11 5.2 0.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 OAG17370.1 - 2e-13 50.3 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG17370.1 - 4e-08 33.0 0.0 6.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG17370.1 - 1.9e-05 23.9 0.3 0.00063 19.0 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 OAG17370.1 - 2.8e-05 23.8 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG17370.1 - 0.052 13.0 0.2 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 OAG17371.1 - 6.3e-24 84.6 29.1 5.5e-23 81.5 29.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 OAG17373.1 - 2e-11 43.8 3.8 1.4e-09 37.7 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 OAG17373.1 - 3.6e-06 26.3 0.0 2.5e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 OAG17373.1 - 0.0006 19.1 0.8 0.00095 18.5 0.8 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG17373.1 - 0.00069 19.3 2.3 0.0039 16.8 1.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG17373.1 - 0.00076 19.7 1.3 0.002 18.3 1.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG17373.1 - 0.0053 16.8 0.8 0.066 13.2 0.5 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG17373.1 - 0.052 12.8 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG17373.1 - 0.06 12.2 0.6 0.11 11.3 0.6 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 OAG17373.1 - 0.12 11.4 0.3 0.61 9.1 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein RTA1 PF04479.13 OAG17374.1 - 3.9e-62 209.5 10.2 3.9e-62 209.5 10.2 1.9 2 0 0 2 2 2 1 RTA1 like protein DUF2157 PF09925.9 OAG17374.1 - 1.4 8.7 9.3 13 5.6 9.3 2.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 OAG17374.1 - 4.3 6.9 14.2 23 4.6 6.7 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Zn_clus PF00172.18 OAG17375.1 - 1.1e-06 28.6 12.8 2.3e-06 27.6 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG17375.1 - 4.9e-06 25.6 0.2 9.7e-06 24.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.11 OAG17376.1 - 1.2e-92 311.3 2.4 1.4e-92 311.1 2.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG17376.1 - 4.7e-05 22.8 0.0 0.00054 19.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG17376.1 - 0.00022 20.8 0.1 0.035 13.6 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG17376.1 - 0.0026 17.5 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold QLQ PF08880.11 OAG17378.1 - 0.058 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 QLQ Dabb PF07876.12 OAG17380.1 - 1.4e-12 48.1 0.1 2.2e-12 47.5 0.1 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short_C2 PF13561.6 OAG17381.1 - 2.4e-57 194.2 1.2 2.9e-57 193.9 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17381.1 - 5.5e-37 127.1 0.7 6.5e-37 126.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1264 PF06884.11 OAG17381.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) ILVD_EDD PF00920.21 OAG17382.1 - 1.2e-152 509.1 1.9 3.7e-152 507.6 1.9 1.6 1 1 0 1 1 1 1 Dehydratase family HepII_C PF18675.1 OAG17382.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Heparinase II C-terminal domain Fungal_trans PF04082.18 OAG17383.1 - 8.8e-19 67.6 0.1 1.4e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17383.1 - 2.1e-08 34.1 7.9 4e-08 33.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldh_2 PF02615.14 OAG17384.1 - 1.8e-122 408.7 2.0 2e-122 408.5 2.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase HTH_Tnp_Tc5 PF03221.16 OAG17385.1 - 3.2e-10 39.9 0.0 6.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG17385.1 - 0.0015 18.3 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_6 PF01418.17 OAG17385.1 - 0.0022 17.9 0.0 0.069 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 OAG17385.1 - 0.062 13.1 0.2 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain GntR PF00392.21 OAG17385.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_49 PF18010.1 OAG17385.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain CAS_CSE1 PF03378.15 OAG17386.1 - 5.5e-186 618.4 1.6 8.1e-186 617.8 0.1 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAG17386.1 - 1.2e-151 504.8 3.0 2.3e-151 503.8 3.0 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAG17386.1 - 4.7e-17 61.7 0.0 2e-16 59.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG17386.1 - 0.013 15.5 0.6 0.2 11.7 0.0 3.3 3 0 0 3 3 3 0 Exportin 1-like protein tRNA-synt_2c PF01411.19 OAG17387.1 - 3.9e-07 29.0 0.0 5.9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAG17387.1 - 9.3e-07 28.9 0.9 1.9e-06 27.8 0.9 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain adh_short PF00106.25 OAG17389.1 - 2.7e-24 85.7 0.1 3.3e-21 75.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG17389.1 - 5.2e-15 55.6 0.0 2.7e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG17389.1 - 2.6e-05 24.2 0.1 6.7e-05 22.9 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 OAG17389.1 - 0.00031 20.3 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG17389.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG17389.1 - 0.098 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GCP_N_terminal PF17681.1 OAG17390.1 - 1.1e-63 215.8 0.1 3.4e-63 214.1 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG17390.1 - 1.4e-63 215.2 1.2 2.6e-63 214.4 1.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Choline_transpo PF04515.12 OAG17391.1 - 1.6e-27 96.6 17.0 1.6e-27 96.6 17.0 2.3 2 0 0 2 2 2 2 Plasma-membrane choline transporter Ras PF00071.22 OAG17392.1 - 4.6e-48 162.9 0.0 1.6e-37 128.6 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG17392.1 - 8.3e-29 100.3 0.0 3e-18 66.2 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG17392.1 - 9.4e-12 44.7 0.0 8.9e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG17392.1 - 2.5e-08 33.7 0.0 6.6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG17392.1 - 3.2e-06 26.7 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG17392.1 - 0.00027 21.0 0.0 0.0022 18.0 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAG17392.1 - 0.0045 16.8 0.0 2.3 8.0 0.0 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAG17392.1 - 0.034 14.0 1.3 1.4 8.8 0.2 2.3 1 1 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 OAG17392.1 - 0.068 12.7 0.1 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mannitol_dh_C PF08125.13 OAG17394.1 - 7.1e-76 254.9 0.0 1.5e-75 253.9 0.0 1.5 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAG17394.1 - 5.7e-46 156.4 0.0 1.1e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GPP34 PF05719.11 OAG17395.1 - 0.017 15.2 0.7 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Metallophos PF00149.28 OAG17398.1 - 6e-33 115.1 0.0 1.3e-32 114.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OAG17398.1 - 1.2e-32 112.0 0.3 2.1e-32 111.3 0.3 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Spt4 PF06093.13 OAG17399.1 - 2.8e-30 104.2 0.2 4.4e-30 103.6 0.2 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TRAPPC10 PF12584.8 OAG17400.1 - 1.5e-32 112.5 0.0 3.3e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 OAG17400.1 - 0.004 16.8 0.4 0.0096 15.5 0.4 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 RTA1 PF04479.13 OAG17401.1 - 1.3e-47 162.1 4.7 1.3e-47 162.1 4.7 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF1275 PF06912.11 OAG17401.1 - 0.13 12.1 3.5 0.17 11.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Asp PF00026.23 OAG17402.1 - 7.6e-77 258.8 1.4 9e-77 258.6 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG17402.1 - 3.7e-13 50.1 1.9 9.2e-12 45.5 0.9 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG17402.1 - 6.4e-07 29.9 0.1 0.27 11.9 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 OAG17402.1 - 0.0078 16.0 0.0 0.11 12.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Rep_fac_C PF08542.11 OAG17404.1 - 3.5e-25 88.2 0.2 1.3e-24 86.4 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAG17404.1 - 2.1e-12 47.1 0.0 8.7e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 OAG17404.1 - 3.7e-11 43.6 0.1 6.4e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG17404.1 - 1.1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG17404.1 - 3.3e-06 27.6 0.0 0.00054 20.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 OAG17404.1 - 3.2e-05 23.8 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OAG17404.1 - 5.9e-05 23.3 0.1 0.089 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG17404.1 - 0.0002 21.2 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 OAG17404.1 - 0.00021 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 OAG17404.1 - 0.00048 20.0 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 OAG17404.1 - 0.0014 18.0 0.1 0.016 14.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OAG17404.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OAG17404.1 - 0.0064 16.8 0.1 0.018 15.3 0.0 2.0 2 1 0 2 2 1 1 AAA C-terminal domain AAA_19 PF13245.6 OAG17404.1 - 0.0079 16.5 0.2 0.029 14.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG17404.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OAG17404.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 OAG17404.1 - 0.015 14.7 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 OAG17404.1 - 0.015 15.0 0.1 0.041 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG17404.1 - 0.026 14.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAG17404.1 - 0.041 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 OAG17404.1 - 0.046 13.5 0.1 0.83 9.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 OAG17404.1 - 0.13 11.8 0.1 1.2 8.7 0.1 2.3 2 1 1 3 3 3 0 AAA domain HpcH_HpaI PF03328.14 OAG17405.1 - 3.2e-27 95.1 0.1 4.1e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 OAG17405.1 - 0.071 12.2 1.2 0.18 10.9 0.6 2.0 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Fungal_trans PF04082.18 OAG17406.1 - 1e-14 54.2 0.1 2.3e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17406.1 - 1.6e-07 31.3 15.6 3.3e-07 30.3 15.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 OAG17407.1 - 2.3e-50 170.4 0.0 3.1e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG17407.1 - 2.7e-20 72.4 0.1 3.7e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG17407.1 - 5.2e-05 23.5 0.1 0.00012 22.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 OAG17407.1 - 6.3e-05 22.8 0.4 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 Rossmann-like domain F420_oxidored PF03807.17 OAG17407.1 - 0.029 15.0 0.2 0.26 11.9 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OAG17407.1 - 0.034 13.4 0.7 0.12 11.7 0.7 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 OAG17408.1 - 5.6e-36 124.2 40.9 5.6e-36 124.2 40.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5360 PF17314.2 OAG17408.1 - 0.27 11.3 4.4 1.8 8.7 0.4 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5360) PEMT PF04191.13 OAG17408.1 - 4.2 7.8 10.0 0.12 12.7 0.6 3.2 2 1 1 3 3 3 0 Phospholipid methyltransferase Peptidase_S10 PF00450.22 OAG17409.1 - 1.9e-97 327.3 3.6 2.5e-97 327.0 3.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Cytomega_UL20A PF05984.12 OAG17409.1 - 0.18 12.1 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Lysine_decarbox PF03641.14 OAG17410.1 - 3e-30 105.0 0.0 4.2e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAG17410.1 - 0.00022 20.9 0.7 0.00048 19.8 0.7 1.6 1 1 0 1 1 1 1 SLOG cluster4 family CLPTM1 PF05602.12 OAG17411.1 - 2.2e-156 521.2 0.2 2.7e-156 520.9 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SyrA PF11089.8 OAG17411.1 - 0.82 9.8 4.5 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Exopolysaccharide production repressor 2TM PF13239.6 OAG17411.1 - 4.7 7.6 8.0 1.6 9.1 0.3 3.1 2 1 0 2 2 2 0 2TM domain CTD_bind PF04818.13 OAG17412.1 - 3.9e-09 37.2 0.0 7.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 OAG17412.1 - 1.7e-05 24.5 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5317 PF17248.2 OAG17412.1 - 0.18 11.8 0.7 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5317) Citrate_synt PF00285.21 OAG17413.1 - 4.9e-102 341.7 0.0 6.2e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 OAG17413.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 OAG17414.1 - 1.2e-27 95.6 2.8 4.8e-12 45.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CRT10 PF08728.10 OAG17414.1 - 4.7e-09 35.0 0.0 4.8e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 CRT10 DUF1275 PF06912.11 OAG17416.1 - 4.5e-48 163.7 14.1 5.5e-48 163.4 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_Mycoplasma PF07672.13 OAG17416.1 - 0.02 14.2 2.6 0.039 13.2 2.8 1.4 1 1 0 1 1 1 0 Mycoplasma MFS transporter Cupin_1 PF00190.22 OAG17417.1 - 3e-41 140.5 0.0 3.9e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG17417.1 - 1.4e-24 85.6 0.7 2.3e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG17417.1 - 3.9e-10 39.3 0.0 0.00015 21.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG17417.1 - 2.8e-06 27.3 0.2 0.0011 18.9 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.14 OAG17417.1 - 0.071 13.3 5.3 2.8 8.1 0.0 2.6 3 0 0 3 3 3 0 ARD/ARD' family Epimerase PF01370.21 OAG17418.1 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG17418.1 - 8.9e-11 41.8 0.6 8.9e-10 38.5 0.6 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG17418.1 - 3.4e-08 33.0 0.0 5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG17418.1 - 4e-07 30.1 0.0 1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG17418.1 - 5.4e-06 25.6 0.0 9.2e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG17418.1 - 6.8e-05 22.4 0.2 0.013 14.9 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.13 OAG17418.1 - 0.00077 19.1 0.1 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAG17418.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FA_desaturase PF00487.24 OAG17419.1 - 1.5e-32 113.4 21.8 2.5e-32 112.7 21.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG17419.1 - 6.6e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF29 PF01724.16 OAG17419.1 - 0.14 12.4 0.5 0.25 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 SnoaL_4 PF13577.6 OAG17420.1 - 8.3e-21 74.4 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4366 PF14283.6 OAG17421.1 - 0.55 10.3 6.4 4.2 7.4 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DIM PF08194.12 OAG17423.1 - 0.11 12.8 1.4 0.11 12.8 1.4 1.9 2 0 0 2 2 2 0 DIM protein Velvet PF11754.8 OAG17425.1 - 1.6e-52 178.9 0.0 5.6e-34 118.2 0.0 4.8 2 2 1 3 3 3 2 Velvet factor Cys_Met_Meta_PP PF01053.20 OAG17426.1 - 9.8e-152 504.9 0.0 1.1e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG17426.1 - 1.3e-09 37.8 0.1 2.1e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OAG17426.1 - 5.7e-09 35.6 0.1 1.1e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG17426.1 - 1.3e-08 34.5 0.0 2.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG17426.1 - 1.6e-07 30.6 0.3 3.2e-07 29.7 0.3 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 OAG17426.1 - 0.00069 18.3 0.1 0.00099 17.7 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase CPSase_L_D2 PF02786.17 OAG17426.1 - 0.06 12.8 0.4 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GDC-P PF02347.16 OAG17426.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 OAG17426.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain AMP-binding PF00501.28 OAG17427.1 - 3.6e-87 292.7 0.0 4.3e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Striatin PF08232.12 OAG17428.1 - 0.33 11.5 2.8 2.9 8.5 0.0 2.5 2 2 0 2 2 2 0 Striatin family MAPEG PF01124.18 OAG17429.1 - 9.5e-10 38.5 5.6 1.8e-09 37.6 5.6 1.4 1 0 0 1 1 1 1 MAPEG family BTB PF00651.31 OAG17432.1 - 0.026 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Rad17 PF03215.15 OAG17432.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain 2-Hacid_dh_C PF02826.19 OAG17433.1 - 1.6e-50 170.9 0.0 2.7e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG17433.1 - 4.1e-16 58.8 0.0 5.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG17433.1 - 0.002 18.3 0.0 0.0055 16.9 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 OAG17433.1 - 0.0038 16.6 0.1 0.64 9.3 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FH2 PF02181.23 OAG17435.1 - 5.5e-82 275.9 4.6 5.5e-82 275.9 4.6 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAG17435.1 - 1.5e-68 230.1 0.4 3.7e-68 228.8 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAG17435.1 - 2.3e-50 170.9 1.3 2.3e-50 170.9 1.3 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain peroxidase PF00141.23 OAG17436.1 - 8.8e-33 113.9 0.1 1.2e-32 113.5 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG17436.1 - 0.00075 19.4 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region HATPase_c PF02518.26 OAG17438.1 - 1.7e-21 76.8 0.1 4.8e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG17438.1 - 9e-18 64.5 0.0 2.5e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG17438.1 - 6.8e-12 45.2 1.1 1.3e-11 44.3 0.0 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAG17438.1 - 2.5e-09 37.9 0.0 7.1e-07 29.9 0.0 2.8 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 OAG17438.1 - 0.039 14.2 0.0 0.28 11.5 0.0 2.6 2 1 0 2 2 2 0 GAF domain HATPase_c_5 PF14501.6 OAG17438.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 GHKL domain DUF2011 PF09428.10 OAG17439.1 - 4.4e-23 81.3 1.0 1e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Borrelia_P83 PF05262.11 OAG17439.1 - 0.31 9.5 12.9 0.5 8.8 12.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 OAG17439.1 - 2.8 6.6 7.5 4.3 6.0 7.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LsmAD PF06741.13 OAG17439.1 - 3.4 8.3 12.2 14 6.4 9.6 2.4 2 0 0 2 2 2 0 LsmAD domain Peptidase_S49_N PF08496.10 OAG17439.1 - 5.1 7.1 9.5 8.2 6.5 9.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 OAG17439.1 - 6 5.5 5.5 9.2 4.9 5.5 1.2 1 0 0 1 1 1 0 Presenilin DUF1720 PF08226.11 OAG17440.1 - 4.1 7.9 7.5 0.5 10.8 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) DUF3632 PF12311.8 OAG17441.1 - 4.3e-32 111.9 0.0 5.4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mso1_Sec1_bdg PF14475.6 OAG17442.1 - 4.4e-19 67.8 0.1 7.8e-19 67.0 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.18 OAG17443.1 - 5.2e-40 137.4 6.1 1.1e-39 136.3 6.1 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAG17443.1 - 4.8e-07 29.4 0.0 0.014 14.8 0.0 3.1 3 0 0 3 3 3 2 Rab-binding domain (RBD) UCH PF00443.29 OAG17446.1 - 9.2e-20 71.2 0.0 2e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG17446.1 - 7.2e-08 32.4 0.3 2.6e-06 27.3 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 OAG17447.1 - 1.2e-81 274.9 25.5 1.4e-81 274.7 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17447.1 - 1e-23 83.8 30.6 1e-23 83.8 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Atg8 PF02991.16 OAG17448.1 - 2.4e-51 172.3 0.3 2.8e-51 172.0 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAG17448.1 - 3.2e-06 27.5 0.0 3.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 OAG17449.1 - 1e-145 484.1 0.1 1.2e-145 483.8 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CFIA_Pcf11 PF11526.8 OAG17450.1 - 6.1e-06 26.6 1.0 2.9e-05 24.5 1.0 2.0 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 OAG17450.1 - 0.00034 20.5 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.13 OAG17450.1 - 0.0023 18.7 0.0 0.0066 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 OAG17450.1 - 6 6.5 7.2 1.9 8.2 2.1 2.5 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Med26 PF08711.11 OAG17451.1 - 5.2e-10 39.2 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Iron_permease PF04120.12 OAG17451.1 - 0.073 12.8 1.7 0.15 11.9 1.7 1.4 1 0 0 1 1 1 0 Low affinity iron permease Pectate_lyase_3 PF12708.7 OAG17452.1 - 4.4e-97 324.1 14.8 1.2e-85 286.8 4.9 3.7 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG17452.1 - 5.3e-06 26.0 0.7 0.14 11.9 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Nup54 PF13874.6 OAG17453.1 - 2.7e-38 131.3 1.5 2.7e-38 131.3 1.5 3.6 3 1 1 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 OAG17453.1 - 8.5e-12 45.8 67.6 4.1e-07 30.8 49.6 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nup54_57_C PF18570.1 OAG17453.1 - 6.7e-05 22.4 4.2 0.00015 21.3 4.2 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Ndc1_Nup PF09531.10 OAG17453.1 - 0.13 10.9 11.2 0.16 10.6 11.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF724 PF05266.14 OAG17453.1 - 0.71 9.7 6.6 0.13 12.1 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4689 PF15755.5 OAG17453.1 - 1.9 8.0 5.9 1 8.9 2.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4689) CHCH PF06747.13 OAG17454.1 - 4.7e-06 26.6 5.9 4.7e-06 26.6 5.9 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 OAG17454.1 - 0.00079 19.4 9.1 0.0016 18.4 4.1 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DnaT PF17948.1 OAG17454.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 DnaT DNA-binding domain Pet191_N PF10203.9 OAG17454.1 - 0.053 13.8 10.1 0.43 10.9 1.8 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Kre28 PF17097.5 OAG17454.1 - 0.056 12.4 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component Cmc1 PF08583.10 OAG17454.1 - 0.49 10.5 15.7 0.84 9.7 5.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 OAG17454.1 - 4.1 7.2 11.0 5.2 6.9 5.4 2.3 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 OAG17454.1 - 6.2 7.1 11.3 5.7 7.2 6.0 2.8 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein PUA_3 PF17785.1 OAG17455.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 PUA-like domain Apc15p PF05841.11 OAG17456.1 - 4.7e-12 46.8 0.0 4.7e-12 46.8 0.0 2.2 3 1 0 3 3 3 1 Apc15p protein BUD22 PF09073.10 OAG17456.1 - 0.12 11.7 16.4 0.15 11.3 16.4 1.2 1 0 0 1 1 1 0 BUD22 AAA_2 PF07724.14 OAG17459.1 - 2.9e-38 131.6 0.0 8.3e-38 130.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAG17459.1 - 2.2e-15 57.2 0.0 8.8e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG17459.1 - 7.2e-09 35.6 0.2 1.5e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG17459.1 - 2.2e-05 24.5 0.0 5.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG17459.1 - 0.00077 19.7 2.6 0.0078 16.5 0.9 2.8 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 OAG17459.1 - 0.003 17.6 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG17459.1 - 0.003 18.1 0.2 0.029 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAG17459.1 - 0.0057 16.4 0.1 0.047 13.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 OAG17459.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 OAG17459.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAG17459.1 - 0.03 14.1 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG17459.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAG17459.1 - 0.033 14.6 3.6 0.043 14.2 0.1 2.8 2 2 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 OAG17459.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 OAG17459.1 - 0.039 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 OAG17459.1 - 0.046 12.8 0.2 0.079 12.0 0.2 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_6 PF12774.7 OAG17459.1 - 0.05 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Sigma54_activ_2 PF14532.6 OAG17459.1 - 0.062 13.4 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 OAG17459.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain IPT PF01745.16 OAG17459.1 - 0.089 12.2 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase DEAD PF00270.29 OAG17459.1 - 0.09 12.5 0.1 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Cytidylate_kin PF02224.18 OAG17459.1 - 0.14 11.8 0.3 2.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 OAG17459.1 - 0.24 10.7 2.2 0.45 9.9 0.2 2.3 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Alpha-amylase_C PF02806.18 OAG17460.1 - 1.7e-27 95.7 0.1 3.7e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 OAG17460.1 - 9.5e-17 61.1 0.1 2.2e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 OAG17460.1 - 6e-13 49.1 0.6 7.7e-10 38.8 0.2 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Suc_Fer-like PF06999.12 OAG17461.1 - 6.1e-57 192.6 0.0 7.6e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Arm PF00514.23 OAG17462.1 - 4e-12 45.7 2.3 0.0018 18.2 0.0 7.1 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAG17462.1 - 0.0029 17.7 7.2 16 6.1 0.0 6.6 5 0 0 5 5 5 1 HEAT repeat IFRD PF05004.13 OAG17462.1 - 0.0046 16.1 0.1 0.031 13.4 0.1 2.4 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAG17462.1 - 0.011 16.2 6.5 9.1 6.9 0.0 5.7 7 0 0 7 7 7 0 HEAT-like repeat MethyTransf_Reg PF10119.9 OAG17462.1 - 0.027 15.2 0.1 0.11 13.3 0.1 2.0 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Cyclin PF08613.11 OAG17464.1 - 3.3e-29 102.3 0.0 8.2e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG17464.1 - 0.00038 20.2 0.1 0.00059 19.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arb2 PF09757.9 OAG17466.1 - 2.5e-92 308.7 0.1 3.3e-92 308.3 0.1 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 OAG17466.1 - 3.4e-89 299.3 0.1 5e-89 298.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Gp_dh_C PF02800.20 OAG17467.1 - 2e-72 242.0 0.1 2.9e-72 241.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAG17467.1 - 4.4e-39 132.9 0.1 1e-38 131.7 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG17467.1 - 0.0085 16.2 0.1 0.039 14.1 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus COX4 PF02936.14 OAG17468.1 - 4.7e-41 140.0 0.4 5.9e-41 139.7 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 OAG17468.1 - 0.0048 17.3 2.4 0.0048 17.3 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3106) MgtE_N PF03448.17 OAG17468.1 - 0.042 14.4 0.1 0.065 13.8 0.1 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain SNARE_assoc PF09335.11 OAG17468.1 - 0.091 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein ATP-synt_ab PF00006.25 OAG17469.1 - 4.5e-61 206.2 0.0 7.4e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAG17469.1 - 5.5e-23 81.3 1.3 1.7e-22 79.7 0.6 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 OAG17469.1 - 0.013 15.4 0.5 0.032 14.1 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 OAG17469.1 - 0.013 14.7 0.4 0.069 12.3 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 OAG17469.1 - 0.016 15.6 0.0 0.82 10.1 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAG17469.1 - 0.042 14.2 1.0 0.5 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG17469.1 - 0.047 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OAG17469.1 - 0.077 13.4 0.5 0.26 11.7 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 OAG17469.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 OAG17469.1 - 0.1 11.9 0.4 0.2 11.0 0.4 1.5 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 OAG17469.1 - 0.11 12.4 0.8 0.61 10.0 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 OAG17469.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 OAG17469.1 - 0.26 10.7 0.1 0.52 9.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein tRNA-synt_1 PF00133.22 OAG17470.1 - 8.8e-53 179.5 0.1 5.1e-22 77.9 0.3 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OAG17470.1 - 2.9e-41 141.0 0.0 4.9e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OAG17470.1 - 1.8e-26 92.8 1.1 6.9e-21 74.4 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG17470.1 - 1.5e-11 44.5 0.1 3.5e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG17470.1 - 0.012 14.9 0.0 0.83 8.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.16 OAG17470.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1d PF00750.19 OAG17470.1 - 0.025 13.5 0.5 0.98 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) zf-ribbon_3 PF13248.6 OAG17470.1 - 0.041 13.3 2.3 4.4 6.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAG17470.1 - 0.15 12.2 2.3 0.5 10.5 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain AA_permease_2 PF13520.6 OAG17471.1 - 5.5e-64 216.6 40.9 1.3e-63 215.4 40.8 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG17471.1 - 1.6e-28 99.6 21.9 1.6e-28 99.6 21.9 2.3 2 1 0 2 2 2 1 Amino acid permease PIG-P PF08510.12 OAG17472.1 - 0.086 12.8 3.6 0.2 11.6 3.6 1.6 1 0 0 1 1 1 0 PIG-P Aminotran_5 PF00266.19 OAG17473.1 - 6.6e-28 97.7 0.0 8.1e-16 57.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.20 OAG17474.1 - 3.2e-111 372.6 1.7 5e-110 368.6 1.7 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG17474.1 - 7.3e-26 91.0 0.0 1.5e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Antimicrobial_6 PF08036.11 OAG17475.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Mito_carr PF00153.27 OAG17476.1 - 2.3e-31 107.6 0.7 3.3e-15 55.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAG17477.1 - 2.2e-65 219.2 0.6 2.6e-65 218.9 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG17477.1 - 8.4e-36 122.8 0.1 1.4e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG17477.1 - 3e-16 59.4 0.1 3.7e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAG17477.1 - 2.5e-05 24.2 0.4 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG17477.1 - 3e-05 24.1 0.0 0.0001 22.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG17477.1 - 5.1e-05 22.9 0.4 0.00013 21.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG17477.1 - 0.00027 20.4 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 OAG17477.1 - 0.00032 21.1 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 OAG17477.1 - 0.00061 19.3 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG17477.1 - 0.00099 18.7 0.0 0.0056 16.2 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OAG17477.1 - 0.0098 16.3 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG17477.1 - 0.034 14.4 0.0 0.072 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG17477.1 - 0.051 13.6 0.1 0.13 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OAG17477.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG17477.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAG17477.1 - 0.093 12.1 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 OAG17477.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 OAG17477.1 - 0.14 12.6 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OAG17477.1 - 0.18 11.4 0.1 1.6 8.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 OAG17478.1 - 1.3e-29 103.3 9.1 1.3e-29 103.3 9.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG17478.1 - 4.5e-08 32.3 5.0 0.00032 19.7 0.2 2.8 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 OAG17478.1 - 1e-07 30.9 10.6 0.0088 14.6 4.9 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 OAG17478.1 - 1.1e-07 31.1 8.7 0.00021 20.3 2.4 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG17478.1 - 1.7e-05 23.4 5.1 0.0016 16.8 0.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 OAG17478.1 - 0.0011 17.5 1.1 0.0011 17.5 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Nuc_H_symport PF03825.16 OAG17478.1 - 0.067 12.2 7.2 0.24 10.3 7.3 1.9 1 1 0 1 1 1 0 Nucleoside H+ symporter MFS_3 PF05977.13 OAG17478.1 - 2 6.7 11.5 0.19 10.0 2.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 OAG17479.1 - 4.3e-78 263.2 21.1 5e-78 263.0 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17479.1 - 2.9e-10 39.6 34.9 1e-08 34.5 27.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG17479.1 - 2.4 6.9 15.3 0.24 10.2 9.3 2.1 2 1 0 2 2 2 0 MFS_1 like family Peptidase_U32 PF01136.19 OAG17480.1 - 0.024 13.8 0.1 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase family U32 EF-hand_4 PF12763.7 OAG17481.1 - 3.4e-34 116.9 0.0 2.6e-13 49.8 0.0 4.2 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAG17481.1 - 1e-09 38.7 0.0 0.00058 20.3 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG17481.1 - 1.5e-05 24.2 0.2 0.77 9.5 0.0 5.1 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 OAG17481.1 - 8.5e-05 22.2 0.3 37 4.6 0.2 5.4 5 0 0 5 5 5 0 EF-hand domain EF-hand_8 PF13833.6 OAG17481.1 - 0.0001 22.0 0.0 10 6.1 0.0 4.8 5 0 0 5 5 5 0 EF-hand domain pair UBA PF00627.31 OAG17481.1 - 0.00029 20.7 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EzrA PF06160.12 OAG17481.1 - 0.0021 16.3 16.7 0.0021 16.3 16.7 1.9 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Tup_N PF08581.10 OAG17481.1 - 0.0023 18.2 4.0 0.0023 18.2 4.0 3.2 2 1 1 3 3 3 1 Tup N-terminal Spc7 PF08317.11 OAG17481.1 - 0.013 14.4 27.3 0.071 12.0 15.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 OAG17481.1 - 0.053 13.6 24.2 0.042 13.9 10.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 OAG17481.1 - 0.053 11.3 23.0 0.074 10.8 23.0 1.0 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.9 OAG17481.1 - 0.071 13.1 26.7 0.019 15.0 7.7 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.12 OAG17481.1 - 0.083 12.0 13.1 0.13 11.3 13.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Filament PF00038.21 OAG17481.1 - 0.1 12.2 26.1 0.13 11.8 13.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 OAG17481.1 - 0.13 12.3 17.6 0.079 13.0 7.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 OAG17481.1 - 0.18 11.7 0.1 0.46 10.4 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CALCOCO1 PF07888.11 OAG17481.1 - 0.22 10.3 22.5 0.48 9.2 22.5 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PI3K_P85_iSH2 PF16454.5 OAG17481.1 - 0.24 11.0 16.6 0.52 9.9 16.6 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AATF-Che1 PF13339.6 OAG17481.1 - 0.3 11.8 14.0 0.4 11.4 4.7 2.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Fib_alpha PF08702.10 OAG17481.1 - 0.48 10.6 22.2 0.066 13.4 11.5 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.13 OAG17481.1 - 0.54 10.1 11.5 0.21 11.4 2.8 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region ADIP PF11559.8 OAG17481.1 - 0.55 10.3 30.9 1.4 9.0 11.3 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OAG17481.1 - 0.68 9.2 26.2 3.4 6.9 13.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1192 PF06698.11 OAG17481.1 - 0.7 10.0 2.7 0.79 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LPP PF04728.13 OAG17481.1 - 0.71 10.3 6.1 9.6 6.7 0.3 3.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper GAS PF13851.6 OAG17481.1 - 0.82 9.0 28.7 1.1 8.6 13.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 OAG17481.1 - 0.93 7.6 22.9 0.35 9.0 11.8 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 OAG17481.1 - 1 9.8 26.7 13 6.2 26.7 2.2 1 1 0 1 1 1 0 Fez1 Laminin_II PF06009.12 OAG17481.1 - 1.7 8.6 17.8 1.4 8.9 10.7 2.4 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.6 OAG17481.1 - 1.8 7.1 15.0 3.8 6.1 15.0 1.5 1 0 0 1 1 1 0 AAA domain Tropomyosin PF00261.20 OAG17481.1 - 1.9 7.8 20.5 2.9 7.2 20.5 1.2 1 0 0 1 1 1 0 Tropomyosin SPATA1_C PF15743.5 OAG17481.1 - 2.4 8.2 20.6 4.5 7.3 20.6 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus PRKG1_interact PF15898.5 OAG17481.1 - 2.6 9.0 26.4 0.37 11.7 7.1 3.0 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 OAG17481.1 - 3.5 8.2 25.3 3.1 8.3 15.4 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 OAG17481.1 - 4.3 7.3 20.2 5 7.1 0.6 3.9 2 2 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.6 OAG17481.1 - 4.9 7.6 21.8 0.12 12.8 11.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Leu_zip PF15294.6 OAG17481.1 - 4.9 6.6 27.7 2.2 7.7 13.1 2.2 1 1 1 2 2 2 0 Leucine zipper DUF724 PF05266.14 OAG17481.1 - 5.5 6.8 20.0 0.11 12.4 6.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) MPS2 PF17060.5 OAG17481.1 - 7.3 5.7 15.8 12 5.1 15.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 MscS_porin PF12795.7 OAG17481.1 - 7.8 6.0 33.7 20 4.6 31.9 2.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FUSC PF04632.12 OAG17481.1 - 8.6 4.8 7.5 13 4.1 7.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MMU163 PF17119.5 OAG17483.1 - 5e-88 294.4 7.1 3e-63 213.3 0.6 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Epimerase PF01370.21 OAG17484.1 - 2.1e-20 73.2 0.1 3.4e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG17484.1 - 1.6e-10 40.9 0.1 2.4e-09 37.1 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG17484.1 - 8.7e-09 34.8 0.0 4.4e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG17484.1 - 1.8e-07 30.6 0.0 2.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG17484.1 - 3.6e-07 29.6 0.3 0.00068 18.9 0.1 2.8 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG17484.1 - 8.7e-07 28.4 0.0 6.1e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG17484.1 - 2.6e-06 27.5 0.0 5e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG17484.1 - 0.12 11.9 0.2 1.5 8.4 0.1 2.4 2 1 0 2 2 2 0 NmrA-like family MFS_1 PF07690.16 OAG17485.1 - 7.9e-39 133.6 45.2 7.9e-39 133.6 45.2 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily AgrB PF04647.15 OAG17485.1 - 0.005 16.2 0.5 0.005 16.2 0.5 2.9 3 1 0 3 3 3 1 Accessory gene regulator B TRI12 PF06609.13 OAG17485.1 - 0.052 12.0 14.5 0.0027 16.2 8.8 1.7 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) NAD_binding_1 PF00175.21 OAG17486.1 - 9.4e-08 32.7 0.0 7e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG17486.1 - 4.2e-07 30.3 0.0 2e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Chorismate_bind PF00425.18 OAG17487.1 - 1.6e-65 221.3 0.2 1.6e-37 129.4 0.1 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 OAG17487.1 - 8.4e-28 97.4 0.0 2.8e-27 95.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAG17487.1 - 1e-16 61.5 0.0 2.3e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAG17487.1 - 7.7e-06 25.8 0.2 2.3e-05 24.2 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 Vps51 PF08700.11 OAG17488.1 - 2.1e-13 50.1 0.2 1.6e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Ku_PK_bind PF08785.11 OAG17488.1 - 0.026 14.7 0.1 0.14 12.3 0.1 2.3 1 0 0 1 1 1 0 Ku C terminal domain like ATG_C PF09333.11 OAG17488.1 - 0.12 12.7 0.2 7.5 7.0 0.0 3.6 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain Mt_ATP-synt_B PF05405.14 OAG17488.1 - 1.9 8.1 5.2 1.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) COG5 PF10392.9 OAG17488.1 - 3.1 8.0 7.4 12 6.1 0.5 3.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 MFS_1 PF07690.16 OAG17489.1 - 4e-09 35.9 25.2 9.3e-09 34.7 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.26 OAG17489.1 - 7.1e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain cwf21 PF08312.12 OAG17490.1 - 2.5e-15 56.3 10.4 2.5e-15 56.3 10.4 2.1 2 0 0 2 2 2 1 cwf21 domain Trans_reg_C PF00486.28 OAG17490.1 - 0.4 10.8 3.1 2 8.5 0.1 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal D123 PF07065.14 OAG17491.1 - 8.8e-120 399.5 1.0 1.1e-119 399.2 1.0 1.1 1 0 0 1 1 1 1 D123 Fungal_trans_2 PF11951.8 OAG17493.1 - 1e-07 31.2 1.4 1.8e-07 30.3 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17493.1 - 1.3e-07 31.6 11.4 2.4e-07 30.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHM7_cyt PF14703.6 OAG17493.1 - 6.5e-05 23.2 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AA_permease PF00324.21 OAG17494.1 - 2.4e-124 415.6 39.3 2.7e-124 415.4 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG17494.1 - 9.9e-33 113.6 44.8 1.3e-32 113.2 44.8 1.2 1 0 0 1 1 1 1 Amino acid permease GCR PF02155.15 OAG17494.1 - 0.0039 16.3 0.2 0.0058 15.7 0.2 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor DUF2101 PF09874.9 OAG17494.1 - 8 6.1 6.6 0.28 10.8 0.4 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Egh16-like PF11327.8 OAG17495.1 - 6e-67 225.6 14.4 7.3e-67 225.3 14.4 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Fungal_trans PF04082.18 OAG17496.1 - 3.4e-27 95.1 0.0 6.9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17496.1 - 2e-09 37.4 10.9 3.2e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCN5L1 PF06320.13 OAG17496.1 - 0.62 10.2 5.4 0.82 9.8 0.0 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Humanin PF15040.6 OAG17498.1 - 0.038 13.4 0.9 1.5 8.4 0.0 2.8 3 0 0 3 3 3 0 Humanin family SPOR PF05036.13 OAG17498.1 - 0.12 12.8 4.8 8.1 6.9 0.3 3.5 2 1 2 4 4 4 0 Sporulation related domain DUF3341 PF11821.8 OAG17498.1 - 0.2 11.3 1.3 5 6.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3341) DNA_photolyase PF00875.18 OAG17498.1 - 0.42 10.6 2.2 24 4.9 0.0 3.3 2 1 1 4 4 4 0 DNA photolyase DUF3328 PF11807.8 OAG17499.1 - 4e-49 167.4 1.2 5e-49 167.1 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tweety PF04906.13 OAG17499.1 - 0.24 10.0 0.3 0.44 9.1 0.0 1.5 2 0 0 2 2 2 0 Tweety Sen15 PF09631.10 OAG17500.1 - 4.4e-23 81.5 0.0 8.1e-23 80.6 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 OAG17502.1 - 4.4e-39 132.5 1.5 8.3e-39 131.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) TFIIA PF03153.13 OAG17503.1 - 0.00014 22.0 11.2 0.00019 21.6 11.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 OAG17503.1 - 1.5 7.0 6.6 2.2 6.5 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ERG4_ERG24 PF01222.17 OAG17504.1 - 3.6e-161 536.7 6.1 4.2e-161 536.5 6.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAG17504.1 - 0.00014 21.5 0.1 0.00033 20.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MWFE PF15879.5 OAG17504.1 - 0.089 13.0 0.1 27 5.0 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Man-6-P_recep PF02157.15 OAG17505.1 - 2.6e-15 56.2 0.0 7e-15 54.8 0.0 1.6 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OAG17505.1 - 4.9e-10 39.7 0.0 1.3e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAG17505.1 - 1.3e-06 28.6 0.1 0.0011 19.0 0.0 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Dynamin_N PF00350.23 OAG17506.1 - 3.3e-15 56.5 0.0 3.3e-15 56.5 0.0 4.1 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAG17506.1 - 1.9e-05 24.7 1.3 0.00071 19.6 0.3 3.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.13 OAG17506.1 - 0.00049 19.3 0.0 0.0013 17.9 0.0 1.7 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 OAG17506.1 - 0.00084 19.3 0.1 0.0059 16.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OAG17506.1 - 0.0013 19.3 0.3 0.0093 16.5 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 OAG17506.1 - 0.0026 18.0 0.4 0.53 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OAG17506.1 - 0.046 12.8 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OAG17506.1 - 0.057 13.8 1.6 0.81 10.0 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 OAG17506.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 OAG17506.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family XhlA PF10779.9 OAG17506.1 - 0.19 12.0 11.5 9.8 6.5 0.1 4.5 3 1 1 4 4 4 0 Haemolysin XhlA TAN PF11640.8 OAG17506.1 - 0.25 11.5 3.4 3.4 7.8 0.0 3.3 3 0 0 3 3 2 0 Telomere-length maintenance and DNA damage repair AAA_23 PF13476.6 OAG17506.1 - 1.7 9.1 0.0 1.7 9.1 0.0 5.7 5 1 0 6 6 6 0 AAA domain DUF3450 PF11932.8 OAG17506.1 - 2.4 7.4 13.4 0.13 11.5 2.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF1515 PF07439.11 OAG17506.1 - 5.6 7.0 6.1 4.6 7.3 1.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Peptidase_M66 PF10462.9 OAG17507.1 - 0.034 13.1 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 COesterase PF00135.28 OAG17510.1 - 3.1e-79 267.2 0.0 4.2e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG17510.1 - 1.4e-06 28.4 0.2 7.1e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG17510.1 - 0.0051 15.7 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase PhyH PF05721.13 OAG17511.1 - 2.2e-13 50.9 0.0 3.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2379 PF09543.10 OAG17511.1 - 0.23 11.7 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Fungal_trans_2 PF11951.8 OAG17512.1 - 6.9e-10 38.3 0.0 8.4e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17512.1 - 3.1e-08 33.6 11.3 5.6e-08 32.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RuBisCO_large PF00016.20 OAG17512.1 - 0.13 11.4 0.1 0.73 9.0 0.0 1.9 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Pkinase PF00069.25 OAG17513.1 - 7.3e-23 81.3 0.0 1.4e-22 80.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG17513.1 - 2.5e-07 30.3 0.0 3.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG17513.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG17513.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EmrE PF13536.6 OAG17517.1 - 0.0007 19.3 0.3 0.0013 18.3 0.2 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter DUF308 PF03729.13 OAG17517.1 - 0.59 10.5 9.3 0.28 11.5 0.4 2.9 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) E1-E2_ATPase PF00122.20 OAG17518.1 - 1.6e-49 167.9 6.4 1.6e-49 167.9 6.4 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OAG17518.1 - 9e-18 65.3 0.0 2.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG17518.1 - 9.5e-11 41.2 0.0 2.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG17518.1 - 0.013 15.3 0.1 0.013 15.3 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG17518.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 OAG17518.1 - 0.12 11.2 4.3 0.31 9.8 4.3 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Aldo_ket_red PF00248.21 OAG17519.1 - 1.1e-41 143.0 0.0 2e-40 138.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family YtfJ_HI0045 PF09695.10 OAG17519.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) DUF382 PF04037.13 OAG17520.1 - 1.6e-56 189.9 0.2 1.6e-56 189.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 OAG17520.1 - 1.6e-22 79.1 3.6 3.5e-22 78.0 3.6 1.7 1 0 0 1 1 1 1 PSP RNA_pol_Rpb2_6 PF00562.28 OAG17522.1 - 8.4e-119 397.1 0.1 1.4e-118 396.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG17522.1 - 5.3e-52 176.3 0.3 8e-52 175.7 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OAG17522.1 - 2.3e-33 114.4 0.9 7.3e-33 112.8 0.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OAG17522.1 - 8.7e-31 107.0 0.5 1.9e-30 106.0 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OAG17522.1 - 1.6e-23 82.8 0.1 4.1e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAG17522.1 - 2.9e-18 65.8 0.0 7.7e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAG17522.1 - 1.6e-09 38.2 4.4 4.3e-09 36.8 1.4 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Mpt_N PF09176.11 OAG17522.1 - 0.029 14.5 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Pga1 PF10333.9 OAG17524.1 - 0.00024 21.0 0.1 0.00051 20.0 0.1 1.8 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator R2K_2 PF18299.1 OAG17524.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Tubulin PF00091.25 OAG17525.1 - 8e-67 225.3 0.0 1.2e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG17525.1 - 2.5e-51 173.1 0.2 4.5e-51 172.3 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAG17525.1 - 0.0018 18.0 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain FA_desaturase PF00487.24 OAG17528.1 - 9.3e-24 84.6 20.4 3e-23 83.0 20.4 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG17528.1 - 7.9e-06 26.1 0.0 2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Molybdopterin PF00384.22 OAG17529.1 - 2.4e-72 244.3 0.0 2.1e-35 122.6 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OAG17529.1 - 4.2e-21 74.8 0.1 9.9e-21 73.6 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 OAG17529.1 - 2.1e-17 63.5 0.0 5.3e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 OAG17529.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 OAG17529.1 - 1.7e-08 34.3 0.6 1.7e-08 34.3 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 OAG17529.1 - 0.023 14.4 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 OAG17529.1 - 0.13 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Na_H_Exchanger PF00999.21 OAG17530.1 - 1.2e-48 165.8 18.6 1.5e-48 165.5 18.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mcl1_mid PF12341.8 OAG17531.1 - 8e-93 311.0 0.0 1.3e-91 307.0 0.0 2.6 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OAG17531.1 - 2.5e-18 66.1 0.5 3.6e-06 27.6 0.2 7.0 7 0 0 7 7 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG17531.1 - 1.6e-15 57.2 0.2 5e-05 23.5 0.0 7.2 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG17531.1 - 1.4e-06 27.7 0.0 4.4e-05 22.7 0.1 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 OAG17531.1 - 7.8e-06 25.1 0.0 0.4 9.6 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG17531.1 - 6.5e-05 22.7 0.0 0.52 10.3 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OAG17531.1 - 0.00015 21.7 0.7 0.26 11.1 0.0 3.6 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OAG17531.1 - 0.0097 14.3 0.0 0.028 12.7 0.0 1.7 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 OAG17531.1 - 0.014 15.9 1.4 10 6.7 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain DNA_pol_alpha_N PF12254.8 OAG17531.1 - 0.028 14.5 1.4 0.098 12.8 1.4 1.9 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal TFIIIC_delta PF12657.7 OAG17531.1 - 0.065 13.2 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term MAGE PF01454.19 OAG17531.1 - 0.14 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 MAGE family PI3K_1B_p101 PF10486.9 OAG17531.1 - 0.16 9.7 0.6 0.24 9.2 0.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 OAG17531.1 - 0.88 9.2 2.8 1.8 8.2 2.8 1.4 1 0 0 1 1 1 0 FAM176 family MFS_1 PF07690.16 OAG17532.1 - 1.9e-36 125.8 31.7 1.9e-36 125.8 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17532.1 - 5.5e-12 45.3 12.7 5.5e-12 45.3 12.7 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG17532.1 - 6.1e-08 31.5 3.9 1.1e-07 30.7 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 OAG17532.1 - 7.4e-06 24.5 1.3 7.4e-06 24.5 1.3 2.4 2 1 0 2 2 2 1 BT1 family DUF2304 PF10066.9 OAG17532.1 - 0.31 11.3 0.0 0.31 11.3 0.0 4.3 5 1 1 6 6 6 0 Uncharacterized conserved protein (DUF2304) LtrA PF06772.11 OAG17533.1 - 1.3e-43 149.6 26.3 1.8e-43 149.2 26.3 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Acetyltransf_6 PF13480.7 OAG17533.1 - 0.47 10.6 4.5 0.66 10.1 2.4 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2012 PF09430.10 OAG17534.1 - 1.7e-26 92.8 0.0 2.2e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 OAG17534.1 - 0.0002 21.0 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Suppressor of PMA 1-7 protein DUF4951 PF16309.5 OAG17534.1 - 0.083 13.0 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) Glyco_hydro_28 PF00295.17 OAG17535.1 - 6.4e-45 153.6 3.4 9.7e-45 153.0 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Phytoreo_S7 PF07236.11 OAG17535.1 - 0.073 11.4 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein PhoD PF09423.10 OAG17535.1 - 0.095 11.7 0.1 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 PhoD-like phosphatase DUF5447 PF17525.2 OAG17535.1 - 0.36 11.3 3.1 0.91 10.0 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5447) BUD22 PF09073.10 OAG17537.1 - 0.028 13.8 17.5 0.04 13.3 17.5 1.1 1 0 0 1 1 1 0 BUD22 zf-C2H2 PF00096.26 OAG17539.1 - 5.5e-15 54.9 9.5 1.2e-05 25.5 0.4 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG17539.1 - 2e-10 40.6 4.5 0.007 17.1 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG17539.1 - 8.7e-06 25.4 2.2 0.044 13.6 0.0 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OAG17539.1 - 4.8e-05 23.5 4.3 0.099 13.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG17539.1 - 0.0012 19.1 3.5 0.14 12.6 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type GAGA PF09237.11 OAG17539.1 - 0.0027 17.4 2.7 0.14 11.9 0.1 2.7 1 1 1 2 2 2 1 GAGA factor zf-H2C2_5 PF13909.6 OAG17539.1 - 0.0032 17.2 15.7 0.038 13.7 1.5 4.7 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 OAG17539.1 - 0.012 16.0 14.3 1 9.9 0.0 3.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 OAG17539.1 - 0.022 15.0 1.0 0.022 15.0 1.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 OAG17539.1 - 0.37 9.9 5.2 2.6 7.1 5.1 2.2 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 OAG17539.1 - 0.47 10.8 12.8 1.3 9.4 0.6 3.7 2 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 OAG17539.1 - 0.5 11.1 7.6 25 5.7 7.5 2.6 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 OAG17539.1 - 0.55 10.9 7.0 0.24 12.1 1.9 2.4 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 OAG17539.1 - 0.93 9.1 4.0 15 5.3 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 OAG17539.1 - 1.7 8.7 5.2 2.1 8.4 0.4 3.0 2 1 1 3 3 3 0 BED zinc finger zf-HYPF PF07503.12 OAG17539.1 - 1.8 8.4 9.3 11 5.9 2.9 3.5 2 1 0 2 2 2 0 HypF finger DUF4405 PF14358.6 OAG17540.1 - 0.041 14.4 0.4 0.041 14.4 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) COesterase PF00135.28 OAG17541.1 - 5.6e-83 279.5 0.0 4.3e-74 250.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG17541.1 - 3e-13 50.1 0.0 4.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG17541.1 - 0.0048 17.5 0.4 0.011 16.3 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipoprotein_21 PF14041.6 OAG17541.1 - 0.052 13.7 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 LppP/LprE lipoprotein AgrB PF04647.15 OAG17542.1 - 0.02 14.2 6.1 0.28 10.5 3.4 2.3 2 0 0 2 2 2 0 Accessory gene regulator B Trp_oprn_chp PF09534.10 OAG17542.1 - 0.082 12.7 0.2 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CcmD PF04995.14 OAG17542.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) NUDIX PF00293.28 OAG17543.1 - 7.7e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AICARFT_IMPCHas PF01808.18 OAG17544.1 - 2.8e-91 306.0 0.0 4e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAG17544.1 - 8.9e-24 83.5 0.0 1.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain CHZ PF09649.10 OAG17545.1 - 1.8e-15 56.1 0.3 1.8e-15 56.1 0.3 1.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ GATase_2 PF00310.21 OAG17547.1 - 2.9e-180 599.5 0.0 4.4e-180 598.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAG17547.1 - 3.9e-156 519.8 0.0 2.3e-155 517.3 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAG17547.1 - 3.4e-113 377.8 0.0 6e-111 370.4 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAG17547.1 - 8.9e-87 289.6 2.5 1.5e-86 288.9 2.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAG17547.1 - 3.4e-24 85.6 0.0 1.3e-23 83.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAG17547.1 - 4.3e-21 74.8 0.1 9.1e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAG17547.1 - 5.7e-09 36.1 0.0 2e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG17547.1 - 1e-07 31.9 1.7 0.0016 18.1 0.5 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG17547.1 - 4.1e-07 30.5 0.5 0.00036 21.0 0.2 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG17547.1 - 8.9e-07 28.5 0.1 0.002 17.4 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG17547.1 - 1e-06 28.4 0.1 2.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG17547.1 - 2.3e-05 23.3 0.2 2.3e-05 23.3 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG17547.1 - 0.00022 20.4 1.0 0.00037 19.7 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 OAG17547.1 - 0.00028 21.3 0.1 1.2 9.6 0.2 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.7 OAG17547.1 - 0.0011 18.4 0.2 0.0011 18.4 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG17547.1 - 0.0014 17.8 0.3 0.32 10.0 0.1 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG17547.1 - 0.0031 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 OAG17547.1 - 0.0044 15.5 0.3 1.4 7.3 0.0 2.8 2 1 0 3 3 3 1 Flavin-binding monooxygenase-like Caskin-tail PF16632.5 OAG17547.1 - 0.0098 16.3 0.3 0.026 14.9 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of Caskin Thi4 PF01946.17 OAG17547.1 - 0.011 15.0 0.2 0.028 13.7 0.2 1.6 1 0 0 1 1 1 0 Thi4 family AdoHcyase_NAD PF00670.21 OAG17547.1 - 0.014 15.4 0.7 2.5 8.1 0.1 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG17547.1 - 0.022 14.1 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG17547.1 - 0.038 14.0 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.18 OAG17547.1 - 0.038 13.0 0.4 0.18 10.8 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.21 OAG17547.1 - 0.055 12.8 0.2 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OAG17547.1 - 0.12 12.4 0.0 24 5.0 0.0 3.1 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 OAG17547.1 - 0.27 11.1 1.4 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain GIDA PF01134.22 OAG17547.1 - 0.34 10.0 2.1 0.43 9.6 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A RNA12 PF10443.9 OAG17548.1 - 2.7e-171 570.2 0.3 2.2e-170 567.2 0.0 2.0 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 OAG17548.1 - 9.3e-05 22.2 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 OAG17548.1 - 0.0002 21.4 0.3 0.0025 17.8 0.1 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 OAG17548.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) ADK PF00406.22 OAG17549.1 - 5.2e-58 195.4 0.0 6.9e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG17549.1 - 4.3e-21 75.8 0.6 8.1e-21 74.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAG17549.1 - 2.6e-17 62.5 0.0 5.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG17549.1 - 9.9e-05 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG17549.1 - 0.0037 17.4 0.0 0.0082 16.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain Dynactin_p22 PF07426.11 OAG17549.1 - 0.033 14.0 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 Cytidylate_kin PF02224.18 OAG17549.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Use1 PF09753.9 OAG17550.1 - 0.0086 15.8 0.0 0.048 13.4 0.0 1.8 2 0 0 2 2 2 1 Membrane fusion protein Use1 GRP PF07172.11 OAG17550.1 - 0.094 13.4 12.8 0.21 12.3 12.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family HET PF06985.11 OAG17551.1 - 8.3e-29 100.8 0.4 1.4e-28 100.0 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MARVEL PF01284.23 OAG17552.1 - 1.7e-16 60.5 18.0 2.4e-16 60.1 18.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain NCE101 PF11654.8 OAG17552.1 - 0.031 14.0 0.2 0.064 13.0 0.2 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 TNFR_16_TM PF18422.1 OAG17552.1 - 0.077 13.0 0.1 0.077 13.0 0.1 3.0 4 0 0 4 4 4 0 Tumor necrosis factor receptor member 16 trans-membrane domain HD PF01966.22 OAG17553.1 - 1.4e-05 25.3 0.5 0.00012 22.3 0.2 2.3 2 1 0 2 2 2 1 HD domain HD_2 PF12917.7 OAG17553.1 - 0.001 18.9 0.6 0.024 14.4 0.2 2.7 3 0 0 3 3 3 1 HD containing hydrolase-like enzyme PDEase_I PF00233.19 OAG17553.1 - 0.026 14.2 1.6 0.03 14.0 0.2 1.7 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S7e PF01251.18 OAG17554.1 - 1.2e-81 272.9 0.0 1.4e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e GST_C_3 PF14497.6 OAG17555.1 - 1.9e-30 105.0 0.3 4.6e-29 100.5 0.3 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG17555.1 - 0.0001 22.2 0.0 0.0003 20.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG17555.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PCRF PF03462.18 OAG17556.1 - 0.015 15.2 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 PCRF domain zf-CCCH PF00642.24 OAG17556.1 - 0.41 10.6 14.3 0.11 12.4 7.6 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAD_binding_3 PF01494.19 OAG17557.1 - 3.9e-25 88.8 0.0 7.5e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG17557.1 - 5.2e-05 22.3 0.2 0.0011 18.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 OAG17557.1 - 0.00026 21.2 0.5 0.00076 19.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG17557.1 - 0.073 12.6 1.8 0.13 11.8 1.0 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG17557.1 - 0.12 11.5 0.5 0.19 10.7 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Gly_kinase PF02595.15 OAG17558.1 - 1.6e-123 412.3 8.6 1.8e-123 412.1 8.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family ComA PF02679.15 OAG17558.1 - 0.052 13.0 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) TubC_N PF18563.1 OAG17558.1 - 0.087 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 TubC N-terminal docking domain MFS_1 PF07690.16 OAG17559.1 - 7.2e-40 137.0 20.1 7.2e-40 137.0 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17559.1 - 4.3e-11 42.3 6.3 4.3e-11 42.3 6.3 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter EpuA PF11772.8 OAG17559.1 - 1.5 8.6 4.7 5.3 6.8 1.3 2.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DASH_Spc19 PF08287.11 OAG17560.1 - 1.2 9.0 14.3 0.51 10.2 10.6 2.1 1 1 1 2 2 2 0 Spc19 DUF848 PF05852.11 OAG17560.1 - 2.7 8.1 11.3 0.25 11.4 0.6 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-H PF05837.12 OAG17560.1 - 3.7 8.0 17.3 3.8 8.0 6.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 OAG17560.1 - 4 7.9 5.5 1.5 9.3 0.3 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 OAG17560.1 - 4.3 7.4 14.3 21 5.1 14.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Haem_degrading PF03928.14 OAG17561.1 - 6.8e-27 93.9 1.0 1.1e-26 93.3 1.0 1.3 1 0 0 1 1 1 1 Haem-degrading Death PF00531.22 OAG17561.1 - 0.034 14.3 0.2 0.062 13.5 0.2 1.4 1 0 0 1 1 1 0 Death domain TMF_TATA_bd PF12325.8 OAG17561.1 - 0.15 12.3 4.2 0.24 11.6 4.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CAP PF00188.26 OAG17562.1 - 1.3e-05 26.1 0.0 2.8e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Bys1 PF04681.12 OAG17564.1 - 0.0089 16.0 1.8 0.014 15.3 1.8 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pyr_redox_3 PF13738.6 OAG17565.1 - 3.1e-10 39.8 0.1 1.1e-07 31.5 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG17565.1 - 2.7e-09 36.7 0.0 1.8e-05 24.1 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG17565.1 - 4.7e-07 28.6 0.1 1e-05 24.2 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG17565.1 - 1.2e-05 25.5 0.8 2.1e-05 24.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG17565.1 - 0.00015 21.8 0.0 0.0094 16.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAG17565.1 - 0.0013 17.9 0.0 0.031 13.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OAG17565.1 - 0.0065 16.9 0.4 0.7 10.4 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAG17565.1 - 0.01 15.0 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG17565.1 - 0.063 12.8 1.4 11 5.5 0.3 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF498 PF04430.14 OAG17565.1 - 0.096 12.8 0.0 57 3.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) 2-Hacid_dh_C PF02826.19 OAG17565.1 - 0.17 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG17565.1 - 0.28 11.8 0.7 53 4.5 1.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 OAG17566.1 - 1.3e-09 38.5 11.4 0.055 14.4 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG17566.1 - 2.6e-05 24.4 0.2 0.022 15.1 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_6 PF13921.6 OAG17566.1 - 0.13 12.5 0.1 0.41 10.9 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain NMD3 PF04981.13 OAG17566.1 - 2.6 7.5 4.1 4.8 6.6 4.1 1.4 1 0 0 1 1 1 0 NMD3 family AA_permease_2 PF13520.6 OAG17567.1 - 2.2e-58 198.1 44.1 1e-37 130.0 31.3 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAG17567.1 - 5.9e-28 97.7 41.4 5.4e-19 68.1 23.3 2.0 1 1 1 2 2 2 2 Amino acid permease Phage_holin_4_1 PF05105.12 OAG17567.1 - 4.8 7.4 11.2 0.4 10.8 3.9 2.9 2 1 0 2 2 2 0 Bacteriophage holin family Sec16_C PF12931.7 OAG17568.1 - 5e-115 384.3 0.1 6.8e-115 383.9 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAG17568.1 - 5.1e-34 117.4 0.0 1.8e-33 115.6 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 OAG17569.1 - 4.1e-54 184.0 11.0 4.1e-54 184.0 11.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG17569.1 - 1.9e-16 59.5 0.5 4.4e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG17569.1 - 5.2e-13 49.8 2.6 3.5e-09 37.3 2.6 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAG17569.1 - 1.3e-07 31.3 0.2 1.3e-07 31.3 0.2 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAG17569.1 - 1.6e-06 28.1 0.0 2.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG17569.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UCH PF00443.29 OAG17570.1 - 4.3e-13 49.3 0.3 8.1e-13 48.4 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG17570.1 - 0.00014 21.5 0.0 0.00033 20.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lectin_C PF00059.21 OAG17571.1 - 0.052 14.3 0.1 0.14 12.9 0.1 1.7 1 0 0 1 1 1 0 Lectin C-type domain TMEM154 PF15102.6 OAG17571.1 - 5.9 6.8 0.0 5.9 6.8 0.0 3.1 4 0 0 4 4 4 0 TMEM154 protein family Myb_DNA-binding PF00249.31 OAG17572.1 - 1.1e-23 83.2 3.9 2.4e-13 50.1 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG17572.1 - 5.2e-16 58.6 2.6 5.2e-12 45.8 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OAG17572.1 - 0.0075 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 SLIDE HTH_23 PF13384.6 OAG17572.1 - 0.048 13.5 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.8 OAG17572.1 - 0.067 13.4 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.12 OAG17572.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Alpha-amylase PF00128.24 OAG17577.1 - 6.8e-59 200.1 0.4 7.7e-57 193.4 0.4 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 OAG17577.1 - 2.2e-29 101.2 0.3 4.9e-29 100.1 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 OAG17577.1 - 0.0003 21.0 0.1 0.0011 19.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF4092 PF13322.6 OAG17577.1 - 0.026 14.4 0.2 0.068 13.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) Alpha-amylase_C PF02806.18 OAG17577.1 - 0.026 15.0 0.1 0.087 13.3 0.1 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain NSP10 PF09401.10 OAG17577.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA synthesis protein NSP10 DUF4096 PF13340.6 OAG17578.1 - 0.024 14.9 0.8 0.055 13.7 0.2 1.9 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) CDC45 PF02724.14 OAG17579.1 - 0.16 10.3 7.7 0.016 13.5 1.8 1.9 2 0 0 2 2 2 0 CDC45-like protein LCD1 PF09798.9 OAG17579.1 - 0.74 8.3 4.1 1.2 7.5 4.1 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM176 PF14851.6 OAG17579.1 - 1.2 8.8 9.2 0.48 10.1 3.2 2.2 2 0 0 2 2 2 0 FAM176 family Ctr PF04145.15 OAG17579.1 - 1.3 9.6 3.1 9.6 6.8 0.7 2.1 2 0 0 2 2 2 0 Ctr copper transporter family AP-5_subunit_s1 PF15001.6 OAG17579.1 - 1.6 8.7 6.7 0.49 10.4 2.5 1.9 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 DUF4637 PF15470.6 OAG17579.1 - 2.7 7.7 13.1 0.54 10.0 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) APC_u15 PF16636.5 OAG17579.1 - 4 8.0 12.8 0.77 10.2 4.9 2.5 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 RR_TM4-6 PF06459.12 OAG17579.1 - 7.6 6.3 18.3 5.5 6.7 8.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Yae1_N PF09811.9 OAG17580.1 - 6e-09 35.5 14.5 4.8e-06 26.2 6.4 2.6 1 1 1 2 2 2 2 Essential protein Yae1, N terminal P68HR PF08061.11 OAG17580.1 - 0.067 13.3 0.7 0.13 12.4 0.7 1.4 1 0 0 1 1 1 0 P68HR (NUC004) repeat Glyoxalase PF00903.25 OAG17581.1 - 2.4e-05 24.5 0.6 3.5e-05 24.0 0.6 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHFR_2 PF06442.11 OAG17581.1 - 0.0085 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 R67 dihydrofolate reductase Serinc PF03348.15 OAG17582.1 - 8.4e-162 539.0 7.2 9.5e-162 538.8 7.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 OAG17583.1 - 4.6e-18 65.3 19.3 3.5e-12 45.9 12.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG17583.1 - 2.6e-16 59.9 5.6 5.3e-16 58.9 5.6 1.5 1 0 0 1 1 1 1 Nodulin-like RskA PF10099.9 OAG17583.1 - 0.072 13.4 0.3 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2034 PF10356.9 OAG17584.1 - 2.8e-24 85.6 0.0 5.5e-15 55.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAG17584.1 - 2.1e-08 34.2 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 OAG17585.1 - 2.9e-38 131.4 8.5 3.5e-38 131.1 8.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex ATG16 PF08614.11 OAG17585.1 - 0.0011 19.2 10.9 0.0019 18.5 10.9 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) GOLGA2L5 PF15070.6 OAG17585.1 - 0.0035 16.1 7.0 0.0043 15.8 7.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Med9 PF07544.13 OAG17585.1 - 0.0044 17.1 7.7 0.0055 16.8 5.0 2.4 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 GHL13 PF14883.6 OAG17585.1 - 0.013 14.6 0.4 0.016 14.3 0.4 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 AAA_13 PF13166.6 OAG17585.1 - 0.031 12.9 1.2 0.034 12.8 1.2 1.1 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.15 OAG17585.1 - 0.044 14.2 5.8 5 7.6 0.1 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus LppA PF16708.5 OAG17585.1 - 0.049 13.5 1.5 0.21 11.5 1.0 2.2 1 1 2 3 3 3 0 Lipoprotein confined to pathogenic Mycobacterium Herpes_UL6 PF01763.16 OAG17585.1 - 0.076 11.5 1.0 0.093 11.2 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like BAR_3 PF16746.5 OAG17585.1 - 0.079 12.7 4.5 0.043 13.5 1.1 1.9 2 0 0 2 2 2 0 BAR domain of APPL family PI3K_P85_iSH2 PF16454.5 OAG17585.1 - 0.11 12.1 6.7 0.042 13.4 4.2 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HTH_40 PF14493.6 OAG17585.1 - 0.12 12.8 1.1 2.7 8.5 1.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Snapin_Pallidin PF14712.6 OAG17585.1 - 0.14 12.6 4.0 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.10 OAG17585.1 - 0.2 11.8 1.9 0.63 10.2 0.7 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 OAG17585.1 - 0.26 10.5 1.0 0.37 10.0 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 OAG17585.1 - 0.3 10.4 11.3 0.76 9.0 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 OAG17585.1 - 1.1 9.9 8.0 59 4.3 8.0 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal End3 PF12761.7 OAG17585.1 - 1.3 9.1 9.1 1.2 9.3 0.8 2.9 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF4407 PF14362.6 OAG17585.1 - 2.1 7.6 7.7 4.1 6.7 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mitofilin PF09731.9 OAG17586.1 - 0.0031 16.4 0.5 0.0042 16.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pep1_7 PF17232.2 OAG17586.1 - 0.047 14.1 0.3 0.28 11.7 0.1 2.2 2 0 0 2 2 2 0 Elicitor peptide 1-7 FAM163 PF15069.6 OAG17588.1 - 0.18 12.2 0.4 0.44 11.0 0.4 1.6 1 0 0 1 1 1 0 FAM163 family HetR_C PF18460.1 OAG17589.1 - 0.038 13.9 0.1 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Sec5 PF15469.6 OAG17590.1 - 2.7e-37 128.5 0.0 6.7e-37 127.2 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAG17590.1 - 0.0003 20.8 0.2 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Mito_carr PF00153.27 OAG17591.1 - 4.8e-59 196.3 5.1 1.7e-20 72.7 1.8 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Rho_N PF07498.12 OAG17592.1 - 0.042 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cyclase PF04199.13 OAG17593.1 - 4.9e-14 52.7 0.0 2.1e-13 50.7 0.0 2.0 3 0 0 3 3 3 1 Putative cyclase Ank_2 PF12796.7 OAG17593.1 - 0.00039 21.0 0.0 0.00083 19.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) OATP PF03137.20 OAG17594.1 - 0.008 14.5 2.4 0.008 14.5 2.4 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_3 PF12698.7 OAG17594.1 - 0.07 12.2 5.7 0.11 11.6 5.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 OAG17594.1 - 4.7 5.9 5.0 3.6 6.2 3.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 OAG17595.1 - 1.2e-58 199.0 51.6 1.4e-58 198.7 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG17595.1 - 5e-13 48.5 39.1 7.1e-13 48.0 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 OAG17595.1 - 0.11 12.5 1.6 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif 60KD_IMP PF02096.20 OAG17595.1 - 1 9.2 11.3 0.072 13.0 3.9 2.4 2 1 0 2 2 2 0 60Kd inner membrane protein COX16 PF14138.6 OAG17596.1 - 0.034 14.6 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 CFEM PF05730.11 OAG17597.1 - 2.5e-14 53.1 11.2 4.1e-14 52.4 11.2 1.4 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.27 OAG17600.1 - 5.3e-47 159.8 0.0 6e-23 81.9 0.0 3.4 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 OAG17600.1 - 1.5e-24 85.8 0.0 5.4e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 Four helical bundle domain SMC_N PF02463.19 OAG17600.1 - 5.2e-16 58.8 0.0 9.7e-06 25.2 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG17600.1 - 1.6e-15 57.7 0.0 0.0025 17.7 0.0 5.0 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG17600.1 - 2.4e-08 33.6 0.0 0.0051 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OAG17600.1 - 9e-08 32.5 0.1 0.01 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG17600.1 - 1e-07 32.7 0.2 0.00011 22.7 0.2 3.3 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.6 OAG17600.1 - 1.3e-07 32.0 0.1 0.0067 16.7 0.0 3.8 5 0 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 OAG17600.1 - 1.7e-07 31.3 0.3 0.00023 21.1 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase AAA PF00004.29 OAG17600.1 - 3.4e-06 27.5 0.1 0.099 13.1 0.1 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OAG17600.1 - 4.4e-06 26.5 0.1 0.12 12.1 0.0 3.0 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OAG17600.1 - 7.5e-06 26.0 0.0 0.0055 16.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG17600.1 - 1.5e-05 25.4 0.3 0.4 11.0 0.0 3.8 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 OAG17600.1 - 5.7e-05 23.7 0.1 0.5 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG17600.1 - 0.00011 22.6 0.0 0.52 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Dynamin_N PF00350.23 OAG17600.1 - 0.00016 21.8 0.4 0.0013 18.8 0.0 2.8 3 0 0 3 3 2 1 Dynamin family NACHT PF05729.12 OAG17600.1 - 0.00018 21.5 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.20 OAG17600.1 - 0.00031 20.0 0.6 0.93 8.6 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit AAA_33 PF13671.6 OAG17600.1 - 0.00032 20.9 0.0 0.95 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Adaptin_N PF01602.20 OAG17600.1 - 0.00032 19.4 2.2 0.0012 17.5 0.6 2.4 1 1 1 2 2 2 1 Adaptin N terminal region AAA_14 PF13173.6 OAG17600.1 - 0.00036 20.6 0.0 0.66 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAG17600.1 - 0.00052 19.8 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAG17600.1 - 0.00059 20.0 2.5 0.14 12.2 0.1 3.5 3 1 0 3 3 3 1 Helicase HerA, central domain AAA_30 PF13604.6 OAG17600.1 - 0.0008 19.2 0.0 1 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 OAG17600.1 - 0.0014 18.2 0.0 1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAG17600.1 - 0.0015 17.6 1.9 0.29 10.1 0.1 2.8 3 0 0 3 3 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OAG17600.1 - 0.0019 18.4 0.0 3.1 8.1 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAG17600.1 - 0.0024 17.5 0.0 1.4 8.5 0.0 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 OAG17600.1 - 0.0025 17.0 0.0 0.17 11.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 OAG17600.1 - 0.004 17.1 0.4 1 9.2 0.0 3.0 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 OAG17600.1 - 0.0046 16.8 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 OAG17600.1 - 0.0052 16.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 OAG17600.1 - 0.0067 16.2 6.5 1.2 8.8 0.0 3.8 5 0 0 5 5 3 2 AAA ATPase domain T2SSE PF00437.20 OAG17600.1 - 0.0068 15.5 0.1 0.97 8.4 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein CLP1_P PF16575.5 OAG17600.1 - 0.011 15.5 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 OAG17600.1 - 0.012 15.6 0.4 9 6.3 0.1 3.4 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HEAT PF02985.22 OAG17600.1 - 0.012 15.8 0.2 9.1 6.9 0.0 3.6 3 0 0 3 3 2 0 HEAT repeat PRK PF00485.18 OAG17600.1 - 0.013 15.2 0.0 0.9 9.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 OAG17600.1 - 0.013 15.7 0.0 4 7.7 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 OAG17600.1 - 0.014 15.3 0.0 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAG17600.1 - 0.014 15.1 0.1 10 5.8 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAG17600.1 - 0.023 14.2 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OAG17600.1 - 0.024 14.2 0.0 2.4 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OAG17600.1 - 0.027 13.7 0.0 3.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 OAG17600.1 - 0.029 13.0 13.9 0.48 9.0 0.0 4.4 5 0 0 5 5 4 0 AAA domain Mg_chelatase PF01078.21 OAG17600.1 - 0.037 13.4 0.0 5.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OAG17600.1 - 0.037 13.8 0.2 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MukB PF04310.12 OAG17600.1 - 0.043 13.6 0.0 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_5 PF07728.14 OAG17600.1 - 0.047 13.7 0.0 13 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) UME PF08064.13 OAG17600.1 - 0.047 13.6 1.5 2.4 8.1 0.0 3.4 3 1 1 4 4 3 0 UME (NUC010) domain NTPase_1 PF03266.15 OAG17600.1 - 0.055 13.4 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 NTPase Arf PF00025.21 OAG17600.1 - 0.092 12.2 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family dNK PF01712.19 OAG17600.1 - 0.094 12.6 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase HEAT_2 PF13646.6 OAG17600.1 - 0.1 13.0 1.8 9.4 6.7 1.4 3.3 1 1 3 4 4 4 0 HEAT repeats ParcG PF10274.9 OAG17600.1 - 0.13 12.4 2.4 4.9 7.2 0.1 3.0 2 1 1 3 3 2 0 Parkin co-regulated protein VHS PF00790.19 OAG17600.1 - 0.14 12.0 1.4 0.47 10.3 1.4 1.9 1 0 0 1 1 1 0 VHS domain Diphthami_syn_2 PF01902.17 OAG17601.1 - 0.045 13.3 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Diphthamide synthase Rick_17kDa_Anti PF05433.15 OAG17602.1 - 0.0021 17.9 21.9 0.004 17.0 21.9 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAG17602.1 - 0.0034 17.4 11.1 0.0034 17.4 11.1 1.8 1 1 1 2 2 2 2 Glycine zipper DUF2076 PF09849.9 OAG17602.1 - 0.0037 17.4 18.1 0.0037 17.4 18.1 3.0 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.12 OAG17602.1 - 3.3 7.3 6.1 0.41 10.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF533) TPR_1 PF00515.28 OAG17603.1 - 8.8e-12 44.3 11.6 0.0011 18.6 0.0 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG17603.1 - 3.4e-11 42.4 13.8 0.00087 19.2 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG17603.1 - 3.7e-10 39.2 5.6 0.0014 18.7 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG17603.1 - 1.9e-07 30.6 5.7 0.08 12.6 0.9 3.8 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 OAG17603.1 - 2.2e-06 27.7 4.9 1e-05 25.6 0.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17603.1 - 2.5e-05 24.7 14.0 0.25 12.2 0.3 6.8 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG17603.1 - 3.8e-05 24.1 5.8 0.55 10.8 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG17603.1 - 7.4e-05 23.0 7.6 0.015 15.5 0.7 5.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG17603.1 - 0.00011 22.3 2.2 2.2 8.9 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG17603.1 - 0.0039 17.1 6.1 3.3 7.9 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG17603.1 - 0.005 16.7 8.6 2 8.4 1.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG17603.1 - 0.0058 17.3 1.1 0.0058 17.3 1.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG17603.1 - 0.24 11.7 10.9 0.14 12.4 3.4 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.12 OAG17603.1 - 0.44 10.6 2.6 12 6.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_6 PF13174.6 OAG17603.1 - 0.61 10.8 9.7 6.6 7.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Epimerase PF01370.21 OAG17605.1 - 7.8e-20 71.4 0.0 9.4e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG17605.1 - 2.6e-16 59.9 0.0 3.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG17605.1 - 7.3e-11 41.6 0.0 9.8e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG17605.1 - 1.2e-08 34.5 0.0 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OAG17605.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 OAG17605.1 - 0.00052 19.3 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 OAG17605.1 - 0.011 15.0 0.0 0.44 9.6 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CENP-F_leu_zip PF10473.9 OAG17609.1 - 6.1e-10 39.3 232.2 0.001 19.1 20.0 13.6 1 1 10 11 11 11 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 OAG17609.1 - 4.7e-09 36.3 187.1 0.029 13.9 13.2 11.7 1 1 9 11 11 11 9 Intermediate filament protein Golgin_A5 PF09787.9 OAG17609.1 - 0.00011 21.8 191.1 0.013 14.9 12.5 8.8 1 1 7 8 8 8 4 Golgin subfamily A member 5 Fez1 PF06818.15 OAG17609.1 - 0.00055 20.4 203.5 0.088 13.3 25.1 9.7 1 1 7 9 9 9 6 Fez1 Spc7 PF08317.11 OAG17609.1 - 0.00075 18.5 232.0 0.0064 15.4 18.7 10.0 1 1 10 11 11 11 7 Spc7 kinetochore protein ATG16 PF08614.11 OAG17609.1 - 0.003 17.8 247.2 2.2 8.4 13.7 10.9 1 1 10 11 11 11 7 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 OAG17609.1 - 0.0053 16.4 7.0 0.0053 16.4 7.0 10.3 2 2 5 8 8 4 1 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 OAG17609.1 - 0.022 14.9 109.9 0.17 12.0 5.9 10.9 2 2 5 10 10 10 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 OAG17609.1 - 0.024 14.5 41.7 19 5.3 0.2 14.8 18 0 0 18 18 18 0 Viral A-type inclusion protein repeat MscS_porin PF12795.7 OAG17609.1 - 0.043 13.4 214.3 0.024 14.2 12.6 9.6 1 1 7 9 9 9 0 Mechanosensitive ion channel porin domain TSC22 PF01166.18 OAG17609.1 - 0.057 13.7 0.1 0.057 13.7 0.1 12.8 13 2 2 15 15 13 0 TSC-22/dip/bun family Phage_GP20 PF06810.11 OAG17609.1 - 0.49 10.2 230.5 0.015 15.1 10.6 16.3 1 1 16 17 17 16 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 OAG17609.1 - 6.7 6.8 272.8 0.035 14.2 25.9 13.6 2 1 12 14 14 12 0 TPR/MLP1/MLP2-like protein Fis1_TPR_C PF14853.6 OAG17610.1 - 4.1e-24 84.4 2.1 6.5e-24 83.8 2.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAG17610.1 - 4.2e-17 61.5 0.0 7.3e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 OAG17610.1 - 3.6e-14 52.8 18.2 2e-12 47.2 9.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 OAG17610.1 - 5e-11 42.1 4.7 1.1e-10 41.1 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAG17610.1 - 3.9e-09 36.2 10.4 1.3e-06 28.1 4.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG17610.1 - 2.6e-08 33.6 18.9 2.8e-07 30.3 9.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG17610.1 - 4.7e-08 32.8 15.9 1.1e-05 25.2 8.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 OAG17610.1 - 3.8e-06 27.0 9.1 8.7e-05 22.7 3.9 2.5 2 0 0 2 2 2 1 zinc-ribbon zf-RING_5 PF14634.6 OAG17610.1 - 9.2e-06 25.5 12.7 1.6e-05 24.7 5.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG17610.1 - 2.9e-05 23.8 12.7 0.0016 18.3 5.8 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG17610.1 - 0.00011 22.4 9.3 0.00011 22.4 9.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG17610.1 - 0.0015 18.5 13.3 0.013 15.5 8.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger TPR_2 PF07719.17 OAG17610.1 - 0.0042 17.1 4.4 0.0081 16.2 4.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat HypA PF01155.19 OAG17610.1 - 0.011 15.7 6.2 0.03 14.4 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 OAG17610.1 - 0.24 11.5 8.3 0.67 10.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAG17610.1 - 0.6 10.2 7.4 1.2 9.3 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 OAG17610.1 - 0.63 10.0 9.4 3.1 7.8 0.7 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.6 OAG17610.1 - 0.64 9.9 11.7 1.7 8.5 4.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OAG17610.1 - 0.7 10.1 2.7 7.4 6.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 OAG17610.1 - 1.1 9.0 18.0 0.55 9.9 8.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 OAG17610.1 - 1.2 9.5 6.6 20 5.6 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 OAG17610.1 - 1.4 9.2 14.8 0.24 11.6 1.3 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_1 PF00515.28 OAG17610.1 - 2.1 8.3 4.8 4.2 7.4 4.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.10 OAG17610.1 - 4.1 7.6 7.0 3.6 7.8 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-ANAPC11 PF12861.7 OAG17610.1 - 5.3 7.2 10.3 0.25 11.4 4.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 OAG17610.1 - 9 6.7 16.2 1 9.8 6.4 2.3 2 0 0 2 2 2 0 RING-like domain Spc24 PF08286.11 OAG17611.1 - 8.3e-34 116.0 0.0 5e-32 110.3 0.0 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 DUF3080 PF11279.8 OAG17611.1 - 0.011 15.0 0.2 0.015 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF773 PF05600.12 OAG17611.1 - 0.1 11.3 2.3 0.18 10.5 2.3 1.4 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 HET PF06985.11 OAG17612.1 - 8.3e-28 97.6 0.1 1.5e-27 96.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleolin_bd PF16725.5 OAG17612.1 - 0.015 14.9 0.4 0.036 13.7 0.4 1.5 1 0 0 1 1 1 0 Nucleolin binding domain DUF1640 PF07798.11 OAG17616.1 - 1.3e-39 136.0 0.9 1.9e-39 135.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2353 PF09789.9 OAG17616.1 - 0.029 13.7 2.2 0.05 13.0 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ECH_1 PF00378.20 OAG17617.1 - 6.6e-24 84.6 0.0 8.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG17617.1 - 1.3e-15 57.8 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEK_C PF08766.11 OAG17617.1 - 0.035 14.0 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 DEK C terminal domain Pet100 PF09803.9 OAG17618.1 - 1.7e-21 76.5 0.3 2.1e-21 76.2 0.3 1.1 1 0 0 1 1 1 1 Pet100 DUF2576 PF10845.8 OAG17618.1 - 0.16 11.6 0.3 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Transcrip_reg PF01709.20 OAG17619.1 - 2e-72 243.5 0.1 2.3e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 OAG17620.1 - 7.6e-10 39.1 3.4 1.2 9.6 0.0 8.2 6 2 2 9 9 9 1 HEAT repeats HEAT PF02985.22 OAG17620.1 - 5.6e-08 32.4 16.6 10 6.7 0.1 9.6 10 0 0 10 10 10 1 HEAT repeat DUF4931 PF16285.5 OAG17620.1 - 0.0053 16.1 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) Vac14_Fab1_bd PF12755.7 OAG17620.1 - 0.021 15.4 0.0 0.91 10.2 0.0 3.3 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG17620.1 - 0.14 12.7 10.7 24 5.5 0.0 7.8 10 0 0 10 10 10 0 HEAT-like repeat Adaptin_N PF01602.20 OAG17620.1 - 0.24 9.9 4.3 0.54 8.7 0.5 3.6 4 1 0 4 4 4 0 Adaptin N terminal region HisKA_3 PF07730.13 OAG17620.1 - 0.4 11.2 2.0 2.8 8.5 0.7 3.3 2 0 0 2 2 2 0 Histidine kinase Nuc_recep-AF1 PF11825.8 OAG17620.1 - 0.41 10.7 2.9 1.8 8.6 0.0 3.4 4 0 0 4 4 4 0 Nuclear/hormone receptor activator site AF-1 CLASP_N PF12348.8 OAG17620.1 - 3.2 7.3 7.1 48 3.4 0.0 5.3 7 1 1 8 8 8 0 CLASP N terminal MFS_1 PF07690.16 OAG17621.1 - 5e-17 61.9 67.0 7e-10 38.4 31.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG17621.1 - 0.0034 15.9 25.7 0.0046 15.4 25.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldedh PF00171.22 OAG17622.1 - 7.7e-155 515.9 0.1 9.6e-155 515.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAG17622.1 - 1.1e-13 50.8 0.3 2.7e-13 49.6 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain LuxC PF05893.14 OAG17622.1 - 0.0003 20.0 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 OAG17622.1 - 0.011 15.2 0.0 0.065 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SnoaL_4 PF13577.6 OAG17623.1 - 9.3e-30 103.4 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DivIC PF04977.15 OAG17623.1 - 0.045 13.5 0.9 0.084 12.7 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator RPE65 PF03055.15 OAG17624.1 - 1.6e-99 334.2 0.0 1.9e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein IBR PF01485.21 OAG17625.1 - 6.6e-11 42.3 33.5 1.4e-07 31.6 16.8 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain HLH PF00010.26 OAG17626.1 - 8.9e-13 48.0 0.5 1.6e-12 47.1 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.12 OAG17626.1 - 0.028 14.1 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein F-112 PF09645.10 OAG17626.1 - 0.6 10.2 4.5 1.1 9.4 3.2 2.1 1 1 0 1 1 1 0 F-112 protein DUF3402 PF11882.8 OAG17627.1 - 9.4e-188 625.0 0.0 1.2e-187 624.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 OAG17627.1 - 2.5e-84 282.9 0.0 3.6e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein FMN_dh PF01070.18 OAG17628.1 - 3.8e-105 351.8 0.0 4.5e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG17628.1 - 9.2e-19 67.4 0.0 1.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG17628.1 - 1.4e-06 27.7 0.1 2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG17628.1 - 1.4e-05 24.3 0.1 0.00051 19.1 0.1 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG17628.1 - 0.014 14.8 0.4 0.024 14.0 0.4 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Tugs PF17840.1 OAG17628.1 - 0.024 14.8 0.1 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain His_biosynth PF00977.21 OAG17628.1 - 0.045 13.2 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.11 OAG17628.1 - 0.054 13.3 0.3 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 ATP11 protein Ribul_P_3_epim PF00834.19 OAG17628.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Methyltransf_23 PF13489.6 OAG17630.1 - 4.3e-05 23.4 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG17630.1 - 0.0054 17.4 0.0 0.0098 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG17630.1 - 0.0097 16.6 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG17630.1 - 0.019 15.7 0.1 0.053 14.3 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 OAG17630.1 - 0.044 12.9 0.1 0.1 11.7 0.1 1.4 1 1 0 1 1 1 0 mRNA capping enzyme Glyco_hydro_61 PF03443.14 OAG17631.1 - 1.4e-62 211.3 0.1 2e-62 210.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CAF-1_p60_C PF15512.6 OAG17631.1 - 0.06 13.8 5.5 0.11 12.9 5.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Gly-rich_Ago1 PF12764.7 OAG17631.1 - 0.2 12.4 6.1 0.4 11.5 4.8 2.2 2 1 1 3 3 3 0 Glycine-rich region of argonaut Med3 PF11593.8 OAG17631.1 - 2.9 7.0 15.0 4.2 6.5 15.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal JmjC PF02373.22 OAG17632.1 - 2e-37 128.1 0.5 3.9e-37 127.2 0.5 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 OAG17632.1 - 2.6e-18 66.2 1.5 4.4e-18 65.5 1.5 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG17632.1 - 3.5e-18 65.6 2.6 6.3e-18 64.8 2.6 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 OAG17632.1 - 1.8e-14 53.4 0.3 5.1e-14 51.9 0.3 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 OAG17632.1 - 0.29 11.1 3.2 0.78 9.7 3.2 1.7 1 0 0 1 1 1 0 PHD-finger Serglycin PF04360.12 OAG17633.1 - 0.016 15.2 0.1 6.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Serglycin YfhO PF09586.10 OAG17633.1 - 4.4 5.4 6.0 0.74 8.0 2.5 1.3 2 0 0 2 2 2 0 Bacterial membrane protein YfhO zf-RING_2 PF13639.6 OAG17634.1 - 7e-10 39.1 4.8 7e-10 39.1 4.8 1.6 2 0 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG17634.1 - 3.7e-06 26.9 1.7 6.8e-06 26.1 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG17634.1 - 0.00012 22.3 6.2 0.00032 20.9 6.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG17634.1 - 0.00015 21.7 2.9 0.0003 20.7 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG17634.1 - 0.0003 20.7 5.8 0.00048 20.0 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG17634.1 - 0.0017 18.2 2.6 0.013 15.3 3.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAG17634.1 - 0.0026 17.3 3.9 0.0052 16.4 3.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 OAG17634.1 - 0.0038 17.1 4.6 0.0066 16.3 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG17634.1 - 0.0044 16.9 2.8 0.0092 15.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG17634.1 - 0.0048 16.7 4.8 0.012 15.5 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG17634.1 - 0.04 14.1 3.5 0.078 13.1 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAG17634.1 - 0.056 13.2 2.5 0.11 12.3 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAG17634.1 - 0.54 10.5 5.2 2.6 8.3 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OAG17634.1 - 1.2 8.9 8.4 0.46 10.3 5.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger FAA_hydrolase PF01557.18 OAG17635.1 - 2.2e-63 213.9 0.0 2.7e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 OAG17635.1 - 0.015 16.2 0.0 0.035 15.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Ssl1 PF04056.14 OAG17636.1 - 3.4e-62 209.7 0.2 1.1e-61 208.1 0.2 1.7 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 OAG17636.1 - 1.3e-14 54.2 10.4 1.3e-14 54.2 10.4 3.6 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 OAG17636.1 - 2.7e-14 53.7 0.0 5.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAG17636.1 - 1.8e-05 25.1 0.0 2.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 OAG17636.1 - 0.043 13.3 2.9 0.094 12.2 2.9 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4769 PF15992.5 OAG17636.1 - 0.22 11.3 2.4 0.42 10.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) RNA_pol_Rpc4 PF05132.14 OAG17636.1 - 0.27 11.7 1.8 34 4.8 1.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-HIT PF04438.16 OAG17636.1 - 9.3 6.2 27.7 0.036 13.9 4.8 3.8 5 0 0 5 5 5 0 HIT zinc finger APC_u14 PF16635.5 OAG17636.1 - 10 6.8 8.3 0.36 11.4 1.9 1.8 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Chs7 PF12271.8 OAG17637.1 - 4e-104 348.0 7.8 4.5e-104 347.8 7.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cytochrom_B_C PF00032.17 OAG17637.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.8 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Sugar_tr PF00083.24 OAG17638.1 - 9.1e-107 357.7 15.2 1.1e-106 357.5 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17638.1 - 1.7e-30 106.1 43.4 7.9e-29 100.7 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG17638.1 - 0.0055 15.6 8.4 0.63 8.8 5.3 2.2 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 OAG17638.1 - 0.021 13.2 2.8 0.043 12.2 2.8 1.4 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) PMT PF02366.18 OAG17639.1 - 2.7e-87 292.4 14.2 2.7e-87 292.4 14.2 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG17639.1 - 5.8e-64 215.4 15.5 5.8e-64 215.4 15.5 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG17639.1 - 9.1e-34 116.9 2.3 1.4e-33 116.3 2.3 1.2 1 0 0 1 1 1 1 MIR domain Carn_acyltransf PF00755.20 OAG17640.1 - 9e-206 685.0 0.0 1.2e-205 684.6 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-rbx1 PF12678.7 OAG17640.1 - 0.085 13.2 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rad51 PF08423.11 OAG17641.1 - 1.7e-34 119.2 0.0 1.1e-33 116.6 0.0 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 OAG17641.1 - 2.2e-06 27.3 0.1 4e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAG17641.1 - 4e-06 26.5 0.6 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAG17641.1 - 2.6e-05 23.7 0.1 0.00011 21.7 0.0 1.8 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 OAG17641.1 - 0.037 14.5 0.2 0.081 13.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OAG17641.1 - 0.048 13.9 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG17641.1 - 0.098 12.6 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 OAG17641.1 - 0.16 12.4 3.0 0.084 13.2 0.5 1.9 2 1 0 2 2 2 0 AAA ATPase domain Inhibitor_I9 PF05922.16 OAG17644.1 - 0.0057 17.3 0.0 0.0067 17.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 PUF PF00806.19 OAG17645.1 - 2.2e-62 203.4 14.7 3.7e-09 35.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.17 OAG17645.1 - 0.041 14.5 0.0 0.097 13.3 0.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Dehyd-heme_bind PF09098.10 OAG17645.1 - 0.063 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding adh_short PF00106.25 OAG17646.1 - 1.6e-39 135.4 0.0 2.2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG17646.1 - 4.1e-26 92.0 0.0 6.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG17646.1 - 2e-11 44.1 0.6 1.9e-10 40.9 0.6 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG17646.1 - 0.00046 19.7 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG17646.1 - 0.001 18.1 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RNase_HII PF01351.18 OAG17647.1 - 3.5e-49 167.4 0.0 8.6e-49 166.1 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease HII zf-RING_2 PF13639.6 OAG17649.1 - 0.0045 17.3 10.4 0.0046 17.2 7.6 2.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG17649.1 - 0.026 14.4 7.7 0.026 14.4 7.7 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CLIP1_ZNF PF16641.5 OAG17649.1 - 0.11 12.4 0.4 0.11 12.4 0.4 3.4 4 0 0 4 4 4 0 CLIP1 zinc knuckle zf-C3HC4_3 PF13920.6 OAG17649.1 - 2.7 7.9 9.1 7.1 6.6 8.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M28 PF04389.17 OAG17650.1 - 2.8e-32 112.1 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG17650.1 - 0.00019 21.2 0.1 0.00049 19.9 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1996 PF09362.10 OAG17652.1 - 1.1e-82 277.6 2.1 1.3e-82 277.3 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Peptidase_A4 PF01828.17 OAG17653.1 - 3.8e-39 134.3 11.2 4.4e-39 134.1 11.2 1.0 1 0 0 1 1 1 1 Peptidase A4 family Hus1 PF04005.12 OAG17654.1 - 6.1e-78 261.9 0.0 7.2e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Ricin_B_lectin PF00652.22 OAG17656.1 - 0.011 16.0 1.3 0.065 13.5 1.3 2.0 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OAG17656.1 - 0.016 15.9 5.0 0.042 14.6 1.9 2.8 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like PapD_C PF02753.17 OAG17656.1 - 0.07 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain Oxidored_FMN PF00724.20 OAG17657.1 - 2e-43 149.0 0.0 2.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MiAMP1 PF09117.10 OAG17658.1 - 0.00027 21.1 1.9 0.00034 20.8 1.9 1.2 1 0 0 1 1 1 1 MiAMP1 Pkinase PF00069.25 OAG17659.1 - 2.7e-20 72.9 0.0 4.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG17659.1 - 1.1e-11 44.6 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2806 PF10987.8 OAG17659.1 - 0.24 11.3 0.0 0.36 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) TrmE_N PF10396.9 OAG17660.1 - 8.5e-36 122.8 0.0 2.2e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 OAG17660.1 - 9.2e-26 91.3 0.1 1.5e-25 90.6 0.1 1.4 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 OAG17660.1 - 9.4e-20 70.8 0.0 1.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG17660.1 - 3.5e-09 36.4 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG17660.1 - 7e-08 32.2 0.1 1.7e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG17660.1 - 4.3e-06 26.9 0.0 1.1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 OAG17660.1 - 0.0011 18.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OAG17660.1 - 0.022 15.3 0.0 0.066 13.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 OAG17660.1 - 0.13 12.5 0.1 0.92 9.7 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAG17660.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PGA_cap PF09587.10 OAG17660.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Ribosomal_L28e PF01778.17 OAG17661.1 - 1.8e-33 115.7 0.1 3.1e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 OAG17661.1 - 8.5e-29 100.1 6.3 8.5e-29 100.1 6.3 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAG17661.1 - 3.6e-05 23.3 10.4 4.4e-05 23.0 10.4 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OAG17661.1 - 0.21 9.8 20.2 0.067 11.4 16.3 1.8 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 OAG17661.1 - 0.53 8.3 19.1 0.78 7.8 19.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAG17661.1 - 8.9 6.0 23.3 18 4.9 23.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sugar_tr PF00083.24 OAG17663.1 - 2.3e-111 372.8 26.5 2.7e-111 372.6 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17663.1 - 1.9e-13 50.1 49.7 3.2e-11 42.8 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Coagulin PF02035.15 OAG17663.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Coagulin DUF2105 PF09878.9 OAG17664.1 - 0.033 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) WLM PF08325.10 OAG17666.1 - 3.2e-51 174.2 0.0 4.9e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 OAG17666.1 - 0.00095 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.17 OAG17666.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 ubiquitin PF00240.23 OAG17666.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family LicD PF04991.13 OAG17667.1 - 6.7e-21 75.5 17.2 1.2e-15 58.3 1.9 3.2 3 1 1 4 4 4 2 LicD family GCP5-Mod21 PF14609.6 OAG17667.1 - 0.056 11.8 3.5 0.074 11.4 3.5 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 TIP49 PF06068.13 OAG17668.1 - 9.3e-153 508.6 2.9 1.2e-152 508.2 2.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG17668.1 - 6.2e-22 77.5 0.1 5.1e-21 74.6 0.0 2.6 3 0 0 3 3 3 1 TIP49 AAA-lid domain RuvB_N PF05496.12 OAG17668.1 - 2.9e-09 36.9 0.3 2.4e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 OAG17668.1 - 2.8e-08 34.2 0.4 7.1e-05 23.2 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG17668.1 - 1.2e-06 29.0 0.3 2.3e-05 24.8 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 OAG17668.1 - 1.3e-06 27.9 1.4 3e-06 26.8 0.8 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 OAG17668.1 - 0.00022 20.7 1.0 0.005 16.2 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG17668.1 - 0.0012 18.9 0.9 0.58 10.2 0.0 3.4 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAG17668.1 - 0.011 15.6 1.4 0.26 11.0 1.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG17668.1 - 0.013 15.7 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAG17668.1 - 0.014 15.8 2.2 0.35 11.2 2.2 2.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG17668.1 - 0.053 13.2 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 OAG17668.1 - 0.062 12.9 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAG17668.1 - 0.073 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 OAG17668.1 - 0.077 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG17668.1 - 0.13 12.5 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain KASH_CCD PF14662.6 OAG17669.1 - 0.0089 15.9 13.4 0.0089 15.9 13.4 7.1 4 3 2 6 6 6 3 Coiled-coil region of CCDC155 or KASH DUF4468 PF14730.6 OAG17669.1 - 0.047 14.0 1.8 7.8 6.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Baculo_PEP_C PF04513.12 OAG17669.1 - 0.13 12.4 62.4 0.095 12.7 0.6 10.9 4 4 6 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus Leucyl-specific PF14795.6 OAG17669.1 - 0.13 12.4 0.3 1.8 8.7 0.0 2.9 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF4530 PF15039.6 OAG17669.1 - 0.24 11.5 3.5 0.37 11.0 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) DUF1910 PF08928.10 OAG17669.1 - 2.2 8.3 6.3 39 4.3 0.1 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) Enolase_N PF03952.16 OAG17669.1 - 3.8 7.7 8.3 3.9 7.7 1.2 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain OPT PF03169.15 OAG17671.1 - 1.1e-102 344.7 36.1 1.3e-102 344.5 36.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PIG-P PF08510.12 OAG17671.1 - 1.7 8.5 7.0 0.12 12.4 0.3 2.4 2 0 0 2 2 2 0 PIG-P TPR_12 PF13424.6 OAG17672.1 - 2.7e-18 66.0 15.1 2.4e-09 37.4 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG17672.1 - 1.5e-08 34.4 1.6 2.9e-05 23.6 0.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 OAG17672.1 - 6.4e-07 29.0 13.2 0.77 10.0 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG17672.1 - 5.7e-06 25.7 0.0 1.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 OAG17672.1 - 9.9e-05 22.8 10.4 5.9 8.0 0.0 6.4 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG17672.1 - 0.00012 22.5 10.2 1.4 9.7 0.1 5.9 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAG17672.1 - 0.00014 22.3 0.6 0.00052 20.4 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain TPR_16 PF13432.6 OAG17672.1 - 0.00036 21.1 10.6 0.00044 20.8 0.5 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG17672.1 - 0.00079 19.1 12.5 0.64 9.9 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG17672.1 - 0.0018 18.7 9.0 3.7 8.4 0.0 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 OAG17672.1 - 0.0026 18.0 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain DUF3856 PF12968.7 OAG17672.1 - 0.0037 17.3 0.6 0.0097 16.0 0.2 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 OAG17672.1 - 0.0037 17.3 1.8 0.0046 17.0 0.2 2.0 2 0 0 2 2 1 1 Putative TPR-like repeat TPR_19 PF14559.6 OAG17672.1 - 0.023 15.2 10.6 0.63 10.6 2.9 4.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG17672.1 - 0.041 14.0 5.0 2.2 8.5 0.2 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAG17672.1 - 0.054 13.1 0.7 8.7 6.0 0.0 3.4 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PGAP1 PF07819.13 OAG17672.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TPR_8 PF13181.6 OAG17672.1 - 0.19 12.0 10.9 1.7 9.1 0.7 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG17672.1 - 0.35 11.1 10.6 0.46 10.7 0.4 4.9 4 1 2 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OAG17672.1 - 0.47 10.4 6.5 43 4.2 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat CorA PF01544.18 OAG17673.1 - 1.6e-09 37.6 0.4 8e-09 35.2 0.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Cas_DxTHG PF09455.10 OAG17673.1 - 0.034 13.7 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Gln-synt_C PF00120.24 OAG17675.1 - 6.6e-52 176.6 0.0 2.5e-51 174.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAG17675.1 - 0.13 12.0 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain WW PF00397.26 OAG17677.1 - 1.6e-11 44.1 0.3 3.8e-11 42.9 0.3 1.7 1 0 0 1 1 1 1 WW domain LRR_4 PF12799.7 OAG17678.1 - 0.0043 17.4 4.4 0.71 10.4 0.1 4.5 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG17678.1 - 0.008 16.1 0.1 0.008 16.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like VEFS-Box PF09733.9 OAG17680.1 - 5.2e-09 36.0 1.0 1e-08 35.1 1.0 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-C2HE PF16278.5 OAG17680.1 - 0.0037 17.7 1.0 0.012 16.0 0.1 2.3 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger FANCL_C PF11793.8 OAG17680.1 - 0.029 14.6 2.6 0.078 13.2 0.7 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 OAG17680.1 - 0.074 12.9 9.0 0.029 14.2 5.2 2.2 2 0 0 2 2 2 0 PHD-finger Cys_rich_KTR PF14205.6 OAG17680.1 - 0.09 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Cysteine-rich KTR Cu_amine_oxidN1 PF07833.11 OAG17680.1 - 0.13 12.7 0.0 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain SET PF00856.28 OAG17683.1 - 4.1e-18 66.3 1.8 2e-17 64.1 0.1 3.0 2 1 0 2 2 2 1 SET domain SRI PF08236.11 OAG17683.1 - 4.5e-15 55.6 9.9 1.3e-14 54.1 9.9 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 OAG17683.1 - 2.7e-09 36.9 10.0 2.7e-09 36.9 10.0 2.3 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAG17683.1 - 2.1e-05 24.5 0.1 2.1e-05 24.5 0.1 2.8 3 0 0 3 3 3 1 TFIIS helical bundle-like domain WW PF00397.26 OAG17683.1 - 2.5e-05 24.2 1.8 6.4e-05 23.0 1.8 1.8 1 0 0 1 1 1 1 WW domain DivIC PF04977.15 OAG17683.1 - 4.9 7.0 6.7 1.3 8.8 0.0 3.2 3 0 0 3 3 3 0 Septum formation initiator PIN_8 PF18476.1 OAG17683.1 - 8.5 6.2 12.1 0.61 9.9 2.0 2.5 3 0 0 3 3 3 0 PIN like domain Rax2 PF12768.7 OAG17684.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Legionella_OMP PF05150.12 OAG17684.1 - 0.21 10.5 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor PBP PF01161.20 OAG17685.1 - 4.6e-10 39.9 0.1 6.1e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HET PF06985.11 OAG17687.1 - 6.5e-27 94.7 1.2 4.2e-23 82.3 0.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 OAG17689.1 - 1.6e-19 69.8 13.4 0.011 16.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG17689.1 - 7.4e-06 26.2 1.6 0.064 13.6 0.0 4.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAG17689.1 - 4.2e-05 22.5 0.9 1.5 7.4 0.0 3.7 2 1 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 OAG17689.1 - 0.00015 20.5 2.6 0.8 8.3 0.1 4.2 1 1 4 5 5 5 2 Nucleoporin Nup120/160 SGL PF08450.12 OAG17689.1 - 0.0037 16.9 0.5 0.56 9.7 0.2 3.2 2 2 2 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Frtz PF11768.8 OAG17689.1 - 0.0041 15.5 0.0 0.0058 15.0 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz XRCC4 PF06632.12 OAG17691.1 - 6e-05 22.1 17.4 0.00018 20.5 17.4 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 OAG17691.1 - 0.00038 20.6 3.8 0.00074 19.7 3.8 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DivIC PF04977.15 OAG17691.1 - 0.19 11.5 4.6 0.1 12.4 2.0 1.9 1 1 0 1 1 1 0 Septum formation initiator ALMT PF11744.8 OAG17691.1 - 0.41 9.4 7.4 0.53 9.1 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 OAG17691.1 - 0.79 9.0 9.2 1.2 8.4 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NpwBP PF12622.7 OAG17691.1 - 2.7 8.8 6.3 0.54 11.1 0.3 2.5 2 0 0 2 2 2 0 mRNA biogenesis factor Aminotran_3 PF00202.21 OAG17694.1 - 2e-118 395.6 0.0 2.3e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Attachment_P66 PF11263.8 OAG17695.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 PRAP PF15314.6 OAG17695.1 - 0.073 13.5 0.4 0.26 11.8 0.4 1.7 1 1 1 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine HET PF06985.11 OAG17696.1 - 4.1e-21 75.9 0.0 7.3e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2378 PF09536.10 OAG17696.1 - 0.039 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Peptidase_S41 PF03572.18 OAG17697.1 - 5.1e-08 32.7 0.0 2.7e-07 30.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase family S41 Bromodomain PF00439.25 OAG17697.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Bromodomain AMP-binding PF00501.28 OAG17698.1 - 1.9e-88 296.9 0.0 2.6e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 OAG17698.1 - 9.7e-50 169.5 0.2 2.2e-49 168.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG17698.1 - 7.5e-27 93.7 0.2 1.8e-26 92.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Condensation PF00668.20 OAG17698.1 - 9.4e-24 83.9 0.6 1.4e-23 83.4 0.6 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 OAG17698.1 - 1.5e-08 34.9 0.0 3.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 OAG17698.1 - 2.8e-05 24.5 0.0 0.00015 22.2 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 OAG17698.1 - 6.7e-05 23.8 0.1 0.00018 22.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 OAG17698.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OAG17698.1 - 1.1 9.2 3.4 0.6 10.0 0.7 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.16 OAG17699.1 - 4.1e-56 190.4 80.7 2.3e-49 168.2 50.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG17699.1 - 0.057 12.3 32.0 0.0051 15.7 12.6 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF2976 PF11190.8 OAG17699.1 - 0.51 10.2 6.2 3.9 7.3 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) OATP PF03137.20 OAG17699.1 - 4 5.6 15.4 1.7 6.9 2.2 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 OAG17700.1 - 7.7e-05 22.5 0.1 0.00018 21.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG17700.1 - 0.00031 20.5 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain Collagen_bind_2 PF12904.7 OAG17700.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase RNA_pol_Rpb8 PF03870.15 OAG17703.1 - 9.6e-42 142.5 0.1 1.1e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF4743 PF15916.5 OAG17704.1 - 2.7e-13 50.0 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAG17704.1 - 6.1e-09 36.0 0.4 9.7e-09 35.4 0.4 1.3 1 0 0 1 1 1 1 NUDIX domain Met_10 PF02475.16 OAG17705.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Trm5_N PF18093.1 OAG17705.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain MTS PF05175.14 OAG17705.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FNIP_N PF14636.6 OAG17706.1 - 1.2e-33 117.2 0.0 1.2e-33 117.2 0.0 4.2 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus zf-CXXC PF02008.20 OAG17707.1 - 0.055 13.5 1.8 0.055 13.5 1.8 2.9 3 0 0 3 3 3 0 CXXC zinc finger domain zf-H2C2_2 PF13465.6 OAG17707.1 - 0.71 10.4 0.2 0.71 10.4 0.2 4.2 4 1 0 4 4 4 0 Zinc-finger double domain LRR_9 PF14580.6 OAG17708.1 - 1e-59 201.0 0.2 1.3e-59 200.6 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OAG17708.1 - 7.4e-13 48.1 11.4 2.7e-08 33.4 1.9 2.7 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OAG17708.1 - 5e-08 33.1 9.6 1.7e-06 28.3 1.9 3.6 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAG17708.1 - 0.00035 20.4 0.5 40 4.6 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OAG17708.1 - 5.1 8.0 8.2 58 4.8 0.3 5.0 5 2 0 5 5 5 0 Leucine Rich Repeat Fip1 PF05182.13 OAG17709.1 - 1.9e-18 65.7 1.8 3.7e-18 64.8 1.8 1.5 1 0 0 1 1 1 1 Fip1 motif Rib_recp_KP_reg PF05104.12 OAG17709.1 - 0.012 16.6 10.0 0.018 16.1 10.0 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Nop14 PF04147.12 OAG17709.1 - 1.9 6.6 5.7 2.2 6.4 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoporin_FG PF13634.6 OAG17710.1 - 2.6e-27 95.5 159.1 3.1e-10 40.7 37.0 3.8 1 1 3 4 4 4 4 Nucleoporin FG repeat region GST_N_2 PF13409.6 OAG17710.1 - 1.1e-21 76.9 0.0 2.6e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG17710.1 - 6.4e-14 51.7 0.3 9.2e-13 48.0 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG17710.1 - 6.3e-06 26.5 0.3 6.2e-05 23.3 0.3 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG17710.1 - 2.3e-05 24.5 0.0 9.9e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1664 PF07889.12 OAG17710.1 - 0.0082 16.2 0.3 0.42 10.6 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 OAG17710.1 - 0.058 13.5 0.2 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Sperm tail Baculo_PEP_C PF04513.12 OAG17710.1 - 0.07 13.2 4.2 0.28 11.2 0.5 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.9 OAG17710.1 - 0.21 10.7 6.2 0.26 10.4 0.1 2.4 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Glycos_transf_1 PF00534.20 OAG17711.1 - 1.5e-34 119.0 0.0 6.2e-34 117.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG17711.1 - 6.6e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAG17711.1 - 5.6e-14 52.7 0.0 1.7e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG17711.1 - 3.1e-06 27.7 0.0 8.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 OAG17711.1 - 0.0012 18.9 0.0 0.41 10.7 0.0 2.7 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 OAG17711.1 - 0.018 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pkinase PF00069.25 OAG17712.1 - 7.7e-25 87.7 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAG17712.1 - 3.7e-11 42.3 10.2 0.071 13.4 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat WD40 PF00400.32 OAG17712.1 - 4.1e-10 40.1 8.7 4.2e-07 30.6 0.1 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT_2 PF13646.6 OAG17712.1 - 1.7e-08 34.7 1.2 0.055 13.9 0.0 4.0 3 0 0 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.17 OAG17712.1 - 4.5e-07 29.4 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 OAG17712.1 - 3.6e-05 24.2 2.3 0.063 13.8 0.2 4.3 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 OAG17712.1 - 0.00042 20.4 0.4 0.22 11.5 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 OAG17712.1 - 0.0086 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RTP1_C1 PF10363.9 OAG17712.1 - 0.13 12.5 0.3 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 SurE PF01975.17 OAG17713.1 - 1.7e-39 135.6 0.0 2.7e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE EF-hand_7 PF13499.6 OAG17714.1 - 0.078 13.4 0.0 0.41 11.1 0.0 2.0 1 1 0 1 1 1 0 EF-hand domain pair Glyco_hydro_30C PF17189.4 OAG17716.1 - 2e-10 40.7 0.1 4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 OAG17716.1 - 6.5e-09 35.2 0.0 9.7e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAG17716.1 - 3.3e-07 29.8 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG17716.1 - 0.0039 16.9 0.0 0.036 13.7 0.0 2.3 2 1 0 3 3 3 1 O-Glycosyl hydrolase family 30 DUF87 PF01935.17 OAG17717.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 1 1 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 OAG17717.1 - 0.17 10.9 4.0 0.061 12.4 0.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GMC_oxred_N PF00732.19 OAG17718.1 - 6.3e-55 186.6 0.0 8.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG17718.1 - 6e-39 133.8 0.0 9.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG17718.1 - 1.2e-05 24.5 0.1 3.9e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAG17718.1 - 1.6e-05 24.7 1.4 9.3e-05 22.2 1.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG17718.1 - 8.9e-05 21.9 0.1 0.053 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG17718.1 - 0.00013 22.1 0.2 0.00031 20.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG17718.1 - 0.00069 19.0 0.0 0.088 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG17718.1 - 0.0026 16.9 0.3 0.097 11.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAG17718.1 - 0.034 13.4 0.1 0.067 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG17718.1 - 0.038 12.7 0.1 0.19 10.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAG17718.1 - 0.047 12.5 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 OAG17718.1 - 0.063 12.3 0.5 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG17718.1 - 0.12 13.0 0.1 9.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG17718.1 - 0.22 11.5 0.6 0.43 10.5 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding TPR_2 PF07719.17 OAG17719.1 - 0.012 15.7 3.2 0.012 15.7 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Radical_SAM PF04055.21 OAG17721.1 - 4.1e-12 46.8 0.0 6.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG17721.1 - 2.8e-05 24.4 0.0 4.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAG17721.1 - 0.026 14.7 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain But2 PF09792.9 OAG17722.1 - 1.1e-32 113.4 0.1 1.3e-32 113.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ADH_zinc_N PF00107.26 OAG17724.1 - 1.9e-10 40.8 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG17724.1 - 7.9e-10 38.6 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG17724.1 - 0.11 13.6 0.0 0.32 12.1 0.0 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Gpr1_Fun34_YaaH PF01184.19 OAG17725.1 - 1.1e-26 93.7 23.2 1.4e-26 93.4 23.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family LPMO_10 PF03067.15 OAG17726.1 - 1.1e-09 39.2 0.6 1.9e-09 38.4 0.6 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading p450 PF00067.22 OAG17728.1 - 6.6e-65 219.6 0.0 7.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol PF00940.19 OAG17730.1 - 1.4e-181 603.9 0.0 1.9e-181 603.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAG17730.1 - 1e-82 278.3 0.4 2.6e-82 276.9 0.4 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Hormone_3 PF00159.18 OAG17730.1 - 0.033 14.3 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Pancreatic hormone peptide RNA_pol_Rpb2_4 PF04566.13 OAG17732.1 - 0.16 12.3 0.1 0.62 10.4 0.1 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Clr2_transil PF16761.5 OAG17733.1 - 2.1e-23 82.9 1.1 5e-23 81.7 1.1 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAG17733.1 - 2e-16 61.1 0.1 7.2e-16 59.3 0.1 2.0 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 OAG17734.1 - 7.2e-59 199.3 1.7 1.4e-57 195.0 1.8 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG17734.1 - 2.2e-14 53.7 0.4 1.4e-13 51.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG17734.1 - 1.7e-07 31.4 0.0 5.8e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 OAG17734.1 - 5.7e-07 29.3 18.4 3.5e-06 26.8 4.4 2.9 2 1 0 2 2 2 2 PHD-finger HDA2-3 PF11496.8 OAG17734.1 - 0.029 13.5 0.1 0.1 11.8 0.1 2.0 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 C1_1 PF00130.22 OAG17734.1 - 0.031 14.1 16.7 0.5 10.3 2.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 OAG17734.1 - 0.44 10.2 13.7 0.021 14.5 1.0 3.4 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Thioredoxin PF00085.20 OAG17735.1 - 3.1e-08 33.5 0.0 4.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OAG17735.1 - 0.045 13.9 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OAG17735.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like CtsR_C PF17727.1 OAG17735.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Redoxin PF08534.10 OAG17735.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin Peptidase_C48 PF02902.19 OAG17736.1 - 8.5e-10 38.8 0.2 0.00015 21.7 0.1 3.8 4 0 0 4 4 4 2 Ulp1 protease family, C-terminal catalytic domain RB_A PF01858.17 OAG17737.1 - 0.019 14.8 0.3 0.028 14.3 0.3 1.2 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain Pex14_N PF04695.13 OAG17738.1 - 0.035 14.8 7.0 0.082 13.6 6.8 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HNF-1_N PF04814.13 OAG17738.1 - 0.037 14.6 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus bZIP_1 PF00170.21 OAG17738.1 - 0.41 10.8 6.5 0.92 9.6 6.5 1.6 1 1 0 1 1 1 0 bZIP transcription factor MENTAL PF10457.9 OAG17739.1 - 0.069 13.0 5.0 0.13 12.0 5.0 1.4 1 0 0 1 1 1 0 Cholesterol-capturing domain Bac_export_2 PF01312.19 OAG17739.1 - 4.9 6.3 8.2 12 5.0 8.2 1.6 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family His_Phos_1 PF00300.22 OAG17740.1 - 2.2e-19 69.9 0.0 3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNase_H2_suC PF08615.11 OAG17741.1 - 6.9e-28 97.6 0.0 8.5e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 OAG17742.1 - 1.5e-67 227.8 0.0 4e-67 226.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAG17742.1 - 4.2e-10 40.2 0.0 8.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG17742.1 - 6.4e-09 36.3 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG17742.1 - 2.9e-07 30.5 0.0 5.4e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG17742.1 - 8e-05 22.5 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG17742.1 - 0.0002 22.1 0.0 0.00043 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OAG17742.1 - 0.0054 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 OAG17742.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 OAG17742.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NUC153 PF08159.12 OAG17745.1 - 4.9e-14 51.8 0.5 4.9e-14 51.8 0.5 4.3 4 0 0 4 4 4 2 NUC153 domain DHquinase_II PF01220.19 OAG17747.1 - 9.4e-63 210.0 0.2 1.1e-62 209.8 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II UPF0669 PF17065.5 OAG17747.1 - 0.051 13.3 0.2 0.12 12.1 0.2 1.7 1 1 0 1 1 1 0 Putative cytokine, C6ORF120 Inositol_P PF00459.25 OAG17748.1 - 1.7e-85 286.8 0.0 2e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 OAG17749.1 - 1.7e-23 82.7 0.0 5.5e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAG17749.1 - 1.2e-06 28.2 0.1 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain DUF1143 PF06608.11 OAG17749.1 - 0.0089 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) OCD_Mu_crystall PF02423.15 OAG17749.1 - 0.0092 15.0 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG17749.1 - 0.025 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG17749.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.24 OAG17750.1 - 9.2e-136 453.3 15.7 1.1e-135 453.1 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17750.1 - 6e-24 84.6 35.2 8.8e-22 77.5 34.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 OAG17751.1 - 2.1e-32 112.3 0.0 4.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 OAG17752.1 - 7.2e-07 28.5 0.8 7.2e-07 28.5 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4255 PF14065.6 OAG17752.1 - 0.013 15.1 0.2 0.037 13.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) Zn_clus PF00172.18 OAG17753.1 - 8.3e-09 35.4 12.9 9.3e-09 35.3 12.9 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 OAG17754.1 - 1.8e-22 80.7 0.0 3.5e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAG17754.1 - 1.9e-18 66.5 0.0 4.9e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAG17754.1 - 1.6e-12 47.8 0.0 3.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 OAG17754.1 - 2.3e-10 40.1 0.1 6.2e-10 38.7 0.1 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAG17754.1 - 3.4e-06 27.2 0.0 7.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_8 PF12780.7 OAG17754.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 SecD-TM1 PF13721.6 OAG17755.1 - 0.12 12.8 0.0 0.66 10.5 0.0 2.0 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Pyr_redox_2 PF07992.14 OAG17756.1 - 8.5e-41 140.1 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG17756.1 - 2.7e-10 40.7 0.0 9.6e-09 35.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 OAG17756.1 - 2.1e-06 26.9 0.3 5.8e-06 25.5 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG17756.1 - 1e-05 25.0 0.6 3.7e-05 23.3 0.6 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 OAG17756.1 - 8.2e-05 21.9 0.6 0.00019 20.7 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OAG17756.1 - 0.0012 19.2 0.1 0.0033 17.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 OAG17756.1 - 0.043 13.1 0.4 0.14 11.4 0.4 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MGC-24 PF05283.11 OAG17756.1 - 0.062 13.7 0.3 0.11 12.9 0.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RdDM_RDM1 PF09187.10 OAG17756.1 - 0.2 11.8 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 WD40 PF00400.32 OAG17757.1 - 1.9e-28 98.1 15.3 8.2e-06 26.5 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG17757.1 - 2.5e-07 29.7 7.8 0.16 10.6 0.7 5.1 3 2 2 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG17757.1 - 2.4e-06 27.7 0.1 1.6 9.1 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 OAG17757.1 - 0.018 14.5 0.2 0.069 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) SKA1 PF07160.12 OAG17757.1 - 0.077 12.8 2.2 0.16 11.8 2.2 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Bax1-I PF01027.20 OAG17759.1 - 0.00042 20.2 0.9 0.00053 19.9 0.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MtN3_slv PF03083.16 OAG17760.1 - 0.25 11.4 2.3 8.8 6.5 0.1 3.5 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Atthog PF18800.1 OAG17760.1 - 5.3 6.9 8.6 0.62 10.0 1.1 2.7 2 1 0 3 3 3 0 Attenuator of Hedgehog AltA1 PF16541.5 OAG17761.1 - 1.1e-15 58.4 0.2 1.5e-15 58.0 0.2 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Ig_3 PF13927.6 OAG17761.1 - 0.028 15.0 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Chlam_OMP6 PF03504.13 OAG17761.1 - 0.15 12.4 0.0 18 5.7 0.0 2.2 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 6 ALG3 PF05208.13 OAG17762.1 - 1.1e-142 475.7 8.2 1.3e-142 475.5 8.2 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2070 PF09843.9 OAG17762.1 - 0.072 11.4 0.9 0.12 10.7 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MgtE PF01769.16 OAG17762.1 - 0.24 11.8 12.5 0.19 12.1 9.0 2.8 2 1 0 2 2 2 0 Divalent cation transporter eIF-1a PF01176.19 OAG17763.1 - 2.1e-19 69.1 0.1 3.2e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MFS_1 PF07690.16 OAG17764.1 - 3.4e-33 115.1 42.2 1.8e-22 79.8 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 OAG17765.1 - 1.4e-32 112.9 0.0 2.4e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) F-box PF00646.33 OAG17766.1 - 1.2e-07 31.4 1.1 3.3e-07 30.0 0.4 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG17766.1 - 2.1e-06 27.5 1.0 7.1e-06 25.8 0.1 2.3 2 1 0 2 2 2 1 F-box-like Sgf11_N PF18519.1 OAG17766.1 - 0.14 11.7 0.1 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain MOZ_SAS PF01853.18 OAG17767.1 - 4.2e-82 274.1 0.0 6.1e-82 273.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 OAG17767.1 - 1.7e-23 82.3 0.3 3.4e-23 81.3 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 OAG17767.1 - 2.9e-23 81.2 1.0 6.1e-23 80.2 1.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 OAG17767.1 - 0.0014 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1918 PF08940.11 OAG17767.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Acetyltransf_1 PF00583.25 OAG17767.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SWIRM-assoc_2 PF16496.5 OAG17767.1 - 1.5 7.6 10.4 3.1 6.6 10.4 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RNase_T PF00929.24 OAG17768.1 - 4.5e-18 66.4 0.0 6.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAG17768.1 - 0.013 15.2 0.0 0.052 13.3 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease ORC6 PF05460.13 OAG17768.1 - 1.8 7.7 9.7 2.7 7.2 9.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Aldo_ket_red PF00248.21 OAG17769.1 - 3.2e-63 213.7 0.0 3.7e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DCAF15_WD40 PF14939.6 OAG17769.1 - 0.27 10.9 0.5 1.1 8.8 0.0 1.9 1 1 1 2 2 2 0 DDB1-and CUL4-substrate receptor 15, WD repeat zf-MYND PF01753.18 OAG17770.1 - 1.7e-08 34.4 11.6 2.6e-08 33.8 11.6 1.3 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 OAG17770.1 - 0.025 12.5 2.0 0.032 12.1 2.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 OAG17770.1 - 0.048 14.0 6.5 0.11 12.9 6.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 OAG17770.1 - 0.54 10.4 4.9 1.2 9.3 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Fer4_2 PF12797.7 OAG17770.1 - 6.7 7.0 7.3 15 6.0 3.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4385 PF14328.6 OAG17771.1 - 3.4e-56 189.4 3.3 3.4e-56 189.4 3.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4385) COA2 PF17051.5 OAG17772.1 - 0.00018 21.5 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 DUF4050 PF13259.6 OAG17772.1 - 0.059 13.7 0.2 0.074 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FXR_C1 PF16096.5 OAG17772.1 - 1.6 9.0 6.8 3.1 8.1 6.8 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Metallophos PF00149.28 OAG17773.1 - 3.1e-32 112.7 0.0 3.9e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG17773.1 - 0.073 13.5 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Clr5 PF14420.6 OAG17775.1 - 1.5e-14 53.9 4.7 4.4e-14 52.4 4.7 1.9 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 OAG17776.1 - 2.3e-16 60.1 0.0 4.1e-11 43.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG17776.1 - 6.8e-16 58.4 0.0 3.7e-06 27.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG17776.1 - 2.2e-15 55.2 0.1 0.002 18.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OAG17776.1 - 4.3e-10 39.6 0.1 0.13 12.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OAG17776.1 - 1.3e-05 25.3 0.1 0.37 11.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) CFEM PF05730.11 OAG17777.1 - 1.1e-14 54.3 14.1 1.9e-14 53.5 14.1 1.4 1 0 0 1 1 1 1 CFEM domain COPI_assoc PF08507.10 OAG17778.1 - 9.2e-34 116.3 4.7 9.8e-34 116.2 4.7 1.0 1 0 0 1 1 1 1 COPI associated protein CBP_BcsF PF11120.8 OAG17778.1 - 0.042 13.9 1.1 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF TMEM72 PF16054.5 OAG17778.1 - 0.32 10.7 1.9 6.8 6.3 0.3 2.1 1 1 1 2 2 2 0 Transmembrane protein family 72 MFS_MOT1 PF16983.5 OAG17778.1 - 2.5 8.5 7.8 33 4.9 7.8 2.4 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily GATA PF00320.27 OAG17779.1 - 1.4e-29 101.4 15.0 7.2e-15 54.3 2.1 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAG17779.1 - 1.3e-05 24.6 3.1 0.0015 18.0 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OAG17779.1 - 0.00056 20.0 2.0 0.97 9.6 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain TDP43_N PF18694.1 OAG17779.1 - 0.0018 18.1 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain DUF2387 PF09526.10 OAG17779.1 - 0.0023 18.0 1.1 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 OAG17779.1 - 0.0054 16.8 2.8 1.6 8.8 0.2 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf zf-RRN7 PF11781.8 OAG17779.1 - 0.023 14.3 3.4 1.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 OAG17779.1 - 0.037 13.9 0.4 0.037 13.9 0.4 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain FYVE PF01363.21 OAG17779.1 - 0.081 13.1 2.8 6.7 6.9 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger eIF-5_eIF-2B PF01873.17 OAG17779.1 - 0.083 12.8 5.4 2.1 8.3 0.8 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 OAG17779.1 - 0.17 12.1 14.3 0.17 12.1 1.0 3.1 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Elf1 PF05129.13 OAG17779.1 - 0.17 11.9 1.5 6.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ras PF00071.22 OAG17781.1 - 3e-59 199.2 0.2 3.6e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG17781.1 - 1.6e-20 73.5 0.0 3.1e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG17781.1 - 7.6e-09 35.2 0.0 8.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG17781.1 - 1.7e-06 27.7 0.2 1e-05 25.2 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG17781.1 - 9.1e-05 22.4 0.3 0.31 10.9 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OAG17781.1 - 0.00023 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OAG17781.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAG17781.1 - 0.002 18.1 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain phiKZ_IP PF12699.7 OAG17781.1 - 0.051 12.7 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins ATP_bind_1 PF03029.17 OAG17781.1 - 0.14 11.9 2.8 0.62 9.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 OAG17781.1 - 0.35 10.6 0.9 2.5 7.8 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein MoCF_biosynth PF00994.24 OAG17782.1 - 3.3e-35 120.9 0.0 4.9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 OAG17783.1 - 1.2e-18 67.0 0.1 1.5e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Arylsulfotrans PF05935.11 OAG17783.1 - 0.094 11.6 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) MFS_1 PF07690.16 OAG17784.1 - 5.9e-32 111.0 38.4 8.1e-32 110.5 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG17784.1 - 2.6e-05 23.3 9.1 2.6e-05 23.3 9.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TMEM174 PF15029.6 OAG17784.1 - 0.26 11.0 0.8 0.83 9.3 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 174 PTR2 PF00854.21 OAG17786.1 - 1.2e-81 274.6 4.3 1.7e-81 274.1 4.3 1.1 1 0 0 1 1 1 1 POT family DUF4682 PF15733.5 OAG17787.1 - 0.046 14.3 0.2 0.88 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) Rhabdo_NV PF02484.15 OAG17787.1 - 0.097 12.8 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein Abhydrolase_6 PF12697.7 OAG17789.1 - 2.1e-12 48.1 1.3 3.1e-12 47.6 1.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG17789.1 - 1.3e-05 24.6 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG17789.1 - 0.0029 17.3 3.6 0.011 15.3 3.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG17789.1 - 0.086 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioredoxin PF00085.20 OAG17790.1 - 1.2e-26 92.7 0.2 2.4e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OAG17790.1 - 2.6e-05 24.0 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG17790.1 - 0.019 15.4 0.1 0.073 13.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG17790.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 OAG17790.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Nuf2 PF03800.14 OAG17791.1 - 7.6e-43 146.0 0.6 1.6e-42 144.9 0.1 1.8 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 OAG17791.1 - 6.6e-32 110.0 14.9 6.6e-32 110.0 14.9 3.8 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain HMGL-like PF00682.19 OAG17792.1 - 9.7e-78 261.4 0.5 1.6e-77 260.6 0.5 1.4 1 0 0 1 1 1 1 HMGL-like NUDIX PF00293.28 OAG17793.1 - 1.4e-26 93.0 0.0 2.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_9 PF13527.7 OAG17795.1 - 1.3e-08 35.0 0.1 3.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG17795.1 - 5.4e-07 29.6 0.0 8.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG17795.1 - 2.9e-06 27.6 0.0 5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG17795.1 - 2.3e-05 24.6 0.0 3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG17795.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 OAG17795.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ERG2_Sigma1R PF04622.12 OAG17797.1 - 2.5e-95 317.7 1.1 2.9e-95 317.5 1.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Glyco_hydro_79C PF16862.5 OAG17798.1 - 8.3e-23 81.2 8.0 5.2e-22 78.7 6.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Luteo_coat PF00894.18 OAG17798.1 - 0.01 15.7 1.6 0.029 14.3 1.6 1.7 1 0 0 1 1 1 0 Luteovirus coat protein HET PF06985.11 OAG17799.1 - 7.2e-26 91.3 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLAC1 PF03595.17 OAG17800.1 - 1.7e-78 264.1 47.6 1.9e-78 264.0 47.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Cellulase PF00150.18 OAG17802.1 - 4.2e-16 59.2 0.0 6.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MCM2_N PF12619.8 OAG17803.1 - 0.033 14.5 3.5 0.13 12.5 2.4 1.9 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 IF-2B PF01008.17 OAG17804.1 - 1.3e-54 185.4 0.0 1.5e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 OAG17804.1 - 0.04 13.8 0.0 0.75 9.7 0.0 2.3 1 1 0 1 1 1 0 DeoR C terminal sensor domain ATP_bind_2 PF03668.15 OAG17806.1 - 7.7e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family RIO1 PF01163.22 OAG17809.1 - 4.4e-42 143.8 0.0 7.9e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OAG17809.1 - 7.6e-31 106.2 0.0 1.6e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OAG17809.1 - 1.1e-08 35.3 0.1 0.00048 20.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG17809.1 - 4e-06 26.3 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RPN1_RPN2_N PF17781.1 OAG17810.1 - 1.8e-116 388.9 0.9 1.8e-116 388.9 0.9 1.6 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAG17810.1 - 4.6e-30 103.4 0.1 7.9e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAG17810.1 - 1.2e-19 69.7 23.9 1.2e-06 28.7 0.4 8.8 9 1 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG17810.1 - 5.3e-08 33.2 0.4 0.013 15.9 0.1 4.3 2 2 1 3 3 3 3 HEAT repeats AP1AR PF15745.5 OAG17810.1 - 0.0039 16.9 0.7 0.029 14.0 0.2 2.1 2 0 0 2 2 2 1 AP-1 complex-associated regulatory protein IFRD PF05004.13 OAG17810.1 - 0.019 14.1 0.7 0.062 12.4 0.7 1.9 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RRM_1 PF00076.22 OAG17811.1 - 5e-23 80.7 0.0 1.1e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAX PF15681.5 OAG17811.1 - 0.54 9.0 2.4 5.5 5.7 0.2 2.1 1 1 1 2 2 2 0 Lymphocyte activation family X FAD_binding_1 PF00667.20 OAG17812.1 - 1.5e-59 201.3 0.0 2e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG17812.1 - 3e-34 118.3 1.2 8.4e-34 116.8 0.8 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAG17812.1 - 1.2e-19 71.0 0.1 6.1e-19 68.7 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MOR2-PAG1_N PF14222.6 OAG17813.1 - 1.1e-200 668.2 0.0 2.1e-200 667.4 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAG17813.1 - 5e-91 305.1 1.7 5e-91 305.1 1.7 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAG17813.1 - 4.1e-37 127.4 7.1 1.6e-14 52.6 0.1 4.1 2 1 1 3 3 3 3 Cell morphogenesis central region Acetyltransf_1 PF00583.25 OAG17817.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CD99L2 PF12301.8 OAG17818.1 - 0.054 13.8 2.0 0.13 12.6 2.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 HMG-CoA_red PF00368.18 OAG17819.1 - 6.4e-138 459.7 6.0 9.9e-138 459.1 6.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 OAG17819.1 - 3.6e-43 147.1 2.1 5.9e-43 146.4 2.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 OAG17819.1 - 3e-16 59.6 2.5 6.2e-16 58.6 2.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAG17819.1 - 4.6e-09 34.9 0.8 4.6e-09 34.9 0.8 1.6 2 0 0 2 2 2 1 Patched family DUF3605 PF12239.8 OAG17820.1 - 1.7e-53 181.0 1.7 2.1e-53 180.8 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) zf-CCCH PF00642.24 OAG17822.1 - 9.2e-09 35.0 17.7 3e-07 30.2 2.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OAG17822.1 - 4.8e-06 26.3 0.0 7.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAG17822.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 2.9 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 OAG17822.1 - 0.009 16.7 3.5 0.5 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 OAG17822.1 - 0.24 11.6 6.3 0.22 11.7 0.7 2.5 2 1 0 2 2 2 0 Zinc-finger containing family LPMO_10 PF03067.15 OAG17823.1 - 0.017 15.8 0.1 0.027 15.1 0.1 1.4 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_76 PF03663.14 OAG17824.1 - 4.4e-78 263.4 8.6 5.7e-78 263.0 8.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG17824.1 - 0.1 11.7 7.8 0.12 11.4 0.3 2.6 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 4HBT PF03061.22 OAG17825.1 - 4.9e-09 36.4 0.1 8.1e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily TMEM247 PF15444.6 OAG17827.1 - 0.1 12.6 0.9 0.23 11.5 0.9 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Pectate_lyase PF03211.13 OAG17828.1 - 3.3e-84 281.5 7.5 3.9e-84 281.2 7.5 1.0 1 0 0 1 1 1 1 Pectate lyase Fungal_trans_2 PF11951.8 OAG17831.1 - 2.1e-08 33.4 0.4 1.1e-07 31.0 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ssu72 PF04722.13 OAG17833.1 - 7.9e-79 263.7 0.0 9.2e-79 263.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.11 OAG17833.1 - 0.49 10.4 4.9 0.68 10.0 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OAG17833.1 - 5 6.5 12.2 7.6 5.9 12.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SH3_9 PF14604.6 OAG17834.1 - 6.8e-10 38.7 0.1 1.9e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG17834.1 - 1.6e-09 37.2 0.0 3.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG17834.1 - 9.2e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Abhydrolase_6 PF12697.7 OAG17835.1 - 7.4e-18 66.0 0.3 1.5e-17 65.0 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG17835.1 - 1.1e-12 48.2 0.0 5.1e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG17835.1 - 5.1e-11 42.3 0.0 5.4e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 OAG17835.1 - 6.8e-11 42.1 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 OAG17835.1 - 4.3e-06 27.0 0.0 8.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.6 OAG17835.1 - 0.0014 18.7 0.0 0.0047 17.1 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Lipase_3 PF01764.25 OAG17835.1 - 0.002 18.0 0.7 0.015 15.2 0.1 2.3 1 1 2 3 3 3 1 Lipase (class 3) Y_phosphatase PF00102.27 OAG17835.1 - 0.0027 17.3 0.0 0.0074 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PGAP1 PF07819.13 OAG17835.1 - 0.0028 17.4 0.3 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 OAG17835.1 - 0.0051 16.7 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 OAG17835.1 - 0.012 15.3 0.2 0.023 14.3 0.0 1.5 2 0 0 2 2 2 0 Putative esterase LCAT PF02450.15 OAG17835.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 OAG17835.1 - 0.04 13.8 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG17835.1 - 0.11 11.4 0.1 0.21 10.5 0.1 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme ILVD_EDD PF00920.21 OAG17836.1 - 3.8e-207 689.0 2.3 4.4e-207 688.8 2.3 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S19e PF01090.19 OAG17837.1 - 6e-58 194.4 0.2 6.8e-58 194.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e BNR PF02012.20 OAG17838.1 - 4.2e-05 22.9 3.1 0.2 11.8 0.1 3.5 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 OAG17838.1 - 0.00017 21.0 0.0 0.00065 19.1 0.0 2.0 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 OAG17838.1 - 0.018 13.9 0.5 2.7 6.7 0.0 1.9 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 OAG17838.1 - 0.023 14.7 5.3 2.2 8.6 2.0 2.8 2 0 0 2 2 2 0 BNR-Asp box repeat Glyco_hydro_61 PF03443.14 OAG17840.1 - 9.6e-62 208.6 0.3 1.3e-61 208.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cas_Cas4 PF01930.17 OAG17841.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF83 TFR_dimer PF04253.15 OAG17843.1 - 6.5e-32 110.2 0.0 1.3e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG17843.1 - 8.3e-22 77.8 0.0 1.5e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG17843.1 - 1e-07 31.8 0.1 2.5e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 OAG17843.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Phage_CII PF05269.11 OAG17847.1 - 0.0075 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage CII protein Slx4 PF09494.10 OAG17848.1 - 3.3e-15 55.8 5.4 3.9e-14 52.3 5.4 2.3 1 1 0 1 1 1 1 Slx4 endonuclease IMS PF00817.20 OAG17849.1 - 4.4e-39 133.9 0.0 8.5e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 OAG17849.1 - 6.6e-11 41.6 0.8 1.7e-10 40.3 0.8 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 OAG17849.1 - 2.3e-07 31.5 0.0 4.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG17849.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Rbsn PF11464.8 OAG17849.1 - 0.087 12.6 0.2 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Fungal_trans PF04082.18 OAG17850.1 - 1.4e-15 57.1 0.9 2.4e-15 56.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17850.1 - 1.8e-08 34.3 10.4 4.6e-08 33.0 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 OAG17850.1 - 0.00023 21.8 19.5 0.00099 19.8 3.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG17850.1 - 0.00025 21.3 20.9 0.0004 20.7 5.5 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 OAG17850.1 - 0.00038 20.7 5.2 0.098 13.1 2.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG17850.1 - 0.00065 19.9 4.8 0.016 15.5 2.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG17850.1 - 0.021 15.2 0.6 0.021 15.2 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 OAG17850.1 - 1.1 9.7 9.5 1.8 8.9 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CrtC PF07143.11 OAG17851.1 - 1.2e-05 26.0 1.0 1.5e-05 25.7 0.3 1.6 2 0 0 2 2 2 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 OAG17851.1 - 1.5e-05 25.3 0.0 7.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Lipocalin-like domain HhH-GPD PF00730.25 OAG17852.1 - 5.5e-05 23.6 0.0 8.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Zn_clus PF00172.18 OAG17853.1 - 4.3e-08 33.1 17.0 8.7e-08 32.2 17.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nnf1 PF03980.14 OAG17853.1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Nnf1 GRASP55_65 PF04495.14 OAG17853.1 - 0.14 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain FAD_binding_7 PF03441.14 OAG17854.1 - 4.1e-79 264.8 0.5 7.2e-79 264.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG17854.1 - 1.2e-37 129.5 0.0 1.9e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF2052 PF09747.9 OAG17854.1 - 0.013 15.7 9.9 0.023 14.8 9.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 OAG17854.1 - 0.083 11.1 10.8 0.11 10.7 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAG17854.1 - 0.12 11.8 9.9 0.18 11.2 9.9 1.2 1 0 0 1 1 1 0 SDA1 N_NLPC_P60 PF12912.7 OAG17854.1 - 0.17 12.2 2.3 0.22 11.9 0.1 2.3 2 0 0 2 2 1 0 NLPC_P60 stabilising domain, N term Prothymosin PF03247.14 OAG17854.1 - 0.32 11.5 27.4 0.66 10.5 27.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family CDC27 PF09507.10 OAG17854.1 - 0.68 9.3 9.2 0.97 8.8 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Usp PF00582.26 OAG17854.1 - 1.3 9.5 8.0 23 5.5 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family CDC45 PF02724.14 OAG17854.1 - 1.7 6.8 9.9 2.4 6.4 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 OAG17854.1 - 1.7 7.9 3.5 2.9 7.2 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_Ag35 PF03286.14 OAG17854.1 - 2.6 7.8 9.3 4.3 7.1 9.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 OAG17854.1 - 3.2 7.7 7.9 5.6 6.9 7.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 OAG17854.1 - 3.6 7.2 9.6 8.1 6.1 9.6 1.5 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 OAG17854.1 - 6.2 6.6 10.0 2.9 7.7 7.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 OAG17854.1 - 6.7 5.9 12.9 13 4.9 12.9 1.4 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 OAG17854.1 - 7.1 5.9 15.2 12 5.2 15.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.18 OAG17854.1 - 9.6 6.0 13.1 46 3.8 11.4 2.2 2 0 0 2 2 2 0 Myc amino-terminal region COesterase PF00135.28 OAG17855.1 - 2e-95 320.6 0.0 2.5e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG17855.1 - 1.1e-05 25.4 0.7 0.0033 17.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG17855.1 - 0.13 11.7 0.4 0.21 11.0 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_115 PF15979.5 OAG17857.1 - 1.5e-135 452.0 6.8 1.5e-135 452.0 6.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 OAG17857.1 - 1.1e-50 171.9 0.3 2.8e-50 170.5 0.0 1.8 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 OAG17857.1 - 0.026 14.8 0.0 0.075 13.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus RuBisCO_large_N PF02788.16 OAG17857.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF2462 PF09495.10 OAG17858.1 - 4.3e-19 69.0 12.2 6.2e-19 68.5 12.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF5427 PF10310.9 OAG17859.1 - 2.3e-171 570.9 1.5 2.7e-171 570.6 1.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 OAG17859.1 - 0.017 15.3 0.2 0.051 13.8 0.2 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 OAG17859.1 - 1.1 8.9 13.2 0.86 9.2 11.5 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 OAG17859.1 - 1.4 7.5 4.1 2.1 6.9 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1090 PF06476.12 OAG17861.1 - 0.0021 18.2 5.8 0.0021 18.2 5.8 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1090) Spc7 PF08317.11 OAG17861.1 - 0.011 14.6 34.8 0.19 10.6 17.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 OAG17861.1 - 0.044 14.0 35.2 0.037 14.3 8.6 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MAD PF05557.13 OAG17861.1 - 0.65 8.3 31.6 0.14 10.5 26.6 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein HMMR_N PF15905.5 OAG17861.1 - 1.4 8.3 31.6 0.11 12.0 18.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4200 PF13863.6 OAG17861.1 - 1.6 9.1 29.8 0.09 13.2 12.5 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) Zn_clus PF00172.18 OAG17861.1 - 1.7 8.8 12.7 4 7.6 12.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS PF13851.6 OAG17861.1 - 2 7.7 32.4 0.51 9.7 19.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 OAG17861.1 - 2.2 8.2 13.6 3.6 7.5 0.2 3.9 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CC2-LZ PF16516.5 OAG17861.1 - 2.4 8.6 24.4 0.043 14.2 4.2 3.6 2 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fez1 PF06818.15 OAG17861.1 - 2.6 8.5 29.9 3.3 8.1 20.7 2.4 1 1 1 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 OAG17861.1 - 9.1 6.4 34.4 0.68 10.1 6.8 3.2 1 1 2 3 3 3 0 Tropomyosin like Transp_cyt_pur PF02133.15 OAG17862.1 - 1.4e-16 60.3 45.2 3e-16 59.2 45.0 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 OAG17862.1 - 0.0081 16.1 0.8 0.0081 16.1 0.8 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5453) Amino_oxidase PF01593.24 OAG17863.1 - 8e-67 226.5 0.0 1.7e-65 222.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG17863.1 - 6.7e-12 45.5 0.2 3.1e-11 43.4 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17863.1 - 0.00012 21.5 0.0 0.0048 16.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG17863.1 - 0.00017 20.9 0.2 0.0028 17.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG17863.1 - 0.00066 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG17863.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG17863.1 - 0.0034 17.0 0.2 0.0094 15.6 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG17863.1 - 0.0039 17.7 0.1 0.23 12.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG17863.1 - 0.0083 16.1 1.2 1.1 9.2 0.1 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAG17863.1 - 0.012 14.9 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG17863.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 OAG17863.1 - 0.016 14.3 0.3 0.024 13.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OAG17863.1 - 0.028 13.7 0.0 0.082 12.2 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG17863.1 - 0.044 12.5 0.2 0.085 11.5 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.23 OAG17864.1 - 2.1e-06 27.4 0.0 3.6e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C14 PF00656.22 OAG17865.1 - 1e-42 146.8 0.0 1.3e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain CtnDOT_TraJ PF07863.11 OAG17866.1 - 0.17 12.5 0.4 0.32 11.7 0.4 1.4 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Hist_deacetyl PF00850.19 OAG17867.1 - 4.4e-84 282.6 0.1 8.3e-84 281.7 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 OAG17868.1 - 4.7e-33 113.7 0.0 8.4e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAG17868.1 - 1.3e-12 48.2 0.3 2.5e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAG17868.1 - 3.5e-08 33.2 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OAG17868.1 - 0.071 13.1 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) ABC_membrane PF00664.23 OAG17869.1 - 1.7e-35 123.0 6.4 4.4e-35 121.7 6.4 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG17869.1 - 1.6e-32 112.8 0.0 9.7e-32 110.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OAG17869.1 - 1.3e-06 28.0 0.0 3.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Oxidored_q3 PF00499.20 OAG17869.1 - 0.0053 16.5 1.1 0.0053 16.5 1.1 3.4 2 2 2 4 4 4 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SbcCD_C PF13558.6 OAG17869.1 - 0.0084 16.3 0.3 0.16 12.2 0.3 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OAG17869.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 OAG17869.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF1980 PF09323.10 OAG17869.1 - 0.77 9.6 0.0 0.77 9.6 0.0 2.9 3 2 0 3 3 3 0 Domain of unknown function (DUF1980) YajC PF02699.15 OAG17869.1 - 4.9 7.1 8.6 15 5.6 0.0 4.0 5 0 0 5 5 5 0 Preprotein translocase subunit WD40 PF00400.32 OAG17870.1 - 2.5e-12 47.1 13.9 3e-07 31.0 0.7 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG17870.1 - 1.2e-07 31.9 0.3 0.0052 17.0 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG17870.1 - 3.4e-07 30.3 0.0 0.0098 15.8 0.1 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Zn_ribbon_17 PF17120.5 OAG17870.1 - 0.00011 21.8 8.3 0.0003 20.4 8.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Ribosomal_S21e PF01249.18 OAG17871.1 - 2.5e-36 123.6 0.0 2.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e F-box-like PF12937.7 OAG17873.1 - 5.3e-05 23.0 0.1 0.00015 21.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG17873.1 - 0.54 10.2 4.3 11 6.0 4.3 2.8 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAG17874.1 - 4.2e-09 36.1 0.0 1.5e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG17874.1 - 5.5e-07 29.3 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Colipase-like PF15083.6 OAG17874.1 - 0.43 10.7 2.7 0.84 9.8 1.7 2.0 1 1 0 1 1 1 0 Colipase-like Aldedh PF00171.22 OAG17875.1 - 1.5e-134 449.0 0.6 1.9e-134 448.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG17875.1 - 0.0056 15.8 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MetW PF07021.12 OAG17875.1 - 0.22 11.1 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AltA1 PF16541.5 OAG17876.1 - 2.5e-07 31.5 0.1 3.2e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 DUF2961 PF11175.8 OAG17877.1 - 0.074 12.7 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Fungal_trans PF04082.18 OAG17878.1 - 3.1e-12 46.1 0.1 1.5e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17878.1 - 2.2e-06 27.7 12.4 4.1e-06 26.8 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Srg PF02118.21 OAG17878.1 - 0.22 11.2 0.1 0.35 10.5 0.1 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor MFS_1 PF07690.16 OAG17879.1 - 1.9e-31 109.3 25.5 1.9e-31 109.3 25.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NIF PF03031.18 OAG17881.1 - 6.9e-39 133.1 0.0 1.4e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_47 PF01532.20 OAG17882.1 - 6.9e-115 384.6 0.0 8.7e-115 384.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HET PF06985.11 OAG17883.1 - 2.9e-27 95.8 4.7 1.1e-26 93.9 4.7 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M36 PF02128.15 OAG17884.1 - 1.7e-157 524.3 2.3 2.2e-157 524.0 2.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 OAG17884.1 - 3.3e-17 62.0 1.9 7.8e-17 60.8 1.9 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 OAG17884.1 - 0.014 15.2 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain DUF4901 PF16244.5 OAG17884.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) ER_lumen_recept PF00810.18 OAG17885.1 - 9.6e-40 136.8 10.5 1.3e-39 136.3 10.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Myb_DNA-bind_6 PF13921.6 OAG17886.1 - 0.0048 17.1 2.6 2 8.7 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 OAG17886.1 - 0.1 12.3 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Aldo_ket_red PF00248.21 OAG17887.1 - 2e-39 135.6 0.0 5.1e-37 127.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 OAG17887.1 - 0.18 11.7 0.1 0.43 10.4 0.0 1.6 2 0 0 2 2 2 0 Development and cell death domain ThiJ_like PF17124.5 OAG17889.1 - 4.2e-15 56.0 0.0 5.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 OAG17889.1 - 7.1e-15 55.2 0.0 2.7e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 OAG17889.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Hydantoinase_B PF02538.14 OAG17890.1 - 7.5e-127 423.8 0.0 1.2e-126 423.2 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG17890.1 - 5.7e-84 281.8 2.2 5.7e-84 281.8 2.2 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG17890.1 - 2.1e-49 167.6 0.4 7.2e-47 159.4 0.0 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OAG17890.1 - 0.001 17.8 1.3 1 7.9 0.1 3.1 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 OAG17890.1 - 0.0028 17.2 0.2 0.24 10.9 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Sugar_tr PF00083.24 OAG17891.1 - 5.8e-70 236.4 28.9 7e-70 236.1 28.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG17891.1 - 1.8e-16 60.0 32.3 4.7e-15 55.4 31.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG17891.1 - 0.00023 20.1 12.2 0.0021 17.0 3.7 2.4 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 OAG17891.1 - 0.26 9.8 33.2 0.047 12.3 3.5 3.2 3 1 0 3 3 3 0 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 OAG17891.1 - 0.36 10.6 2.2 5.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like ADH_N PF08240.12 OAG17892.1 - 8.6e-30 102.8 1.2 1.4e-29 102.2 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG17892.1 - 1.7e-13 50.7 0.0 2.5e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG17892.1 - 3.6e-05 23.3 2.0 0.00021 20.8 2.0 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAG17892.1 - 0.035 13.3 0.1 2.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 OAG17892.1 - 0.13 13.3 0.0 0.44 11.6 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.6 OAG17892.1 - 0.75 9.0 3.2 6.3 6.0 1.6 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_N PF00456.21 OAG17893.1 - 3.2e-117 391.2 0.0 4.9e-117 390.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG17893.1 - 1.4e-44 151.9 0.0 2.7e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG17893.1 - 1.4e-10 41.1 0.0 4.6e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG17893.1 - 2.4e-06 27.0 0.0 7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAG17893.1 - 0.0001 22.1 0.4 0.0018 18.1 0.4 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAG17893.1 - 0.0012 17.8 0.1 0.0028 16.6 0.1 1.6 1 0 0 1 1 1 1 Dehydrogenase E1 component dCMP_cyt_deam_1 PF00383.23 OAG17894.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG17894.1 - 8.4e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SET PF00856.28 OAG17895.1 - 2.2e-14 54.2 1.8 1.4e-13 51.6 0.0 3.0 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 OAG17895.1 - 2e-08 33.7 1.2 1.3e-05 24.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG17895.1 - 0.00053 19.7 0.1 0.0054 16.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17895.1 - 0.021 15.6 0.2 0.13 13.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.6 OAG17895.1 - 0.068 12.9 0.7 0.18 11.5 0.7 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_16 PF13432.6 OAG17895.1 - 0.085 13.5 0.2 0.085 13.5 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG17895.1 - 0.099 12.9 0.1 0.36 11.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SAF PF08666.12 OAG17895.1 - 0.15 12.7 0.0 31 5.3 0.0 3.2 3 0 0 3 3 3 0 SAF domain TPR_6 PF13174.6 OAG17895.1 - 0.17 12.6 1.2 0.72 10.6 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF PF00209.18 OAG17896.1 - 4.7e-84 283.0 34.5 4.7e-84 283.0 34.5 3.0 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family Cupin_2 PF07883.11 OAG17897.1 - 3.6e-05 23.4 0.2 0.15 11.8 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 OAG17897.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Cupin ADH_zinc_N_2 PF13602.6 OAG17898.1 - 7.7e-12 46.4 0.0 1.2e-11 45.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG17898.1 - 5.1e-10 39.2 0.0 1.3e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG17898.1 - 6.6e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RGCC PF15151.6 OAG17899.1 - 0.093 12.9 1.3 0.41 10.9 1.3 2.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family GPP34 PF05719.11 OAG17899.1 - 0.14 12.2 1.9 0.14 12.2 0.3 1.8 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Abhydrolase_1 PF00561.20 OAG17901.1 - 7.7e-13 48.7 0.0 1e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG17901.1 - 4.2e-06 27.5 0.0 5.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG17901.1 - 2.2e-05 23.9 0.0 7.3e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG17901.1 - 0.046 13.4 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase CSN5_C PF18323.1 OAG17902.1 - 0.58 11.1 4.5 0.48 11.4 2.6 1.8 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain RIC3 PF15361.6 OAG17902.1 - 0.8 10.1 4.5 0.25 11.7 1.7 1.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DivIC PF04977.15 OAG17902.1 - 2 8.2 5.4 3.6 7.4 5.4 1.5 1 0 0 1 1 1 0 Septum formation initiator HAUS6_N PF14661.6 OAG17902.1 - 2.2 7.8 7.4 3.2 7.3 7.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GTA_holin_3TM PF11351.8 OAG17902.1 - 2.5 8.6 4.9 4.1 8.0 4.9 1.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Spc7 PF08317.11 OAG17902.1 - 2.9 6.7 8.3 3.9 6.3 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Methyltransf_31 PF13847.6 OAG17903.1 - 1.5e-30 106.0 0.0 1.9e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG17903.1 - 6.5e-19 68.4 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG17903.1 - 8.7e-17 61.2 0.1 2.3e-16 59.8 0.1 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG17903.1 - 2.9e-16 59.9 0.0 5.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG17903.1 - 3.4e-11 43.2 0.0 5.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG17903.1 - 1.7e-10 41.5 0.0 3.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG17903.1 - 2.2e-09 37.1 0.2 3.3e-09 36.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OAG17903.1 - 1.4e-07 31.4 0.0 3.2e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG17903.1 - 4.1e-06 26.3 0.0 5.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAG17903.1 - 2.5e-05 24.3 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG17903.1 - 0.00012 21.7 0.1 0.00021 20.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 OAG17903.1 - 0.0046 16.6 0.1 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 OAG17903.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 OAG17903.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.19 OAG17903.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAG17903.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 OAG17903.1 - 0.036 13.6 0.2 0.071 12.6 0.2 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.11 OAG17903.1 - 0.043 12.7 0.0 0.063 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) N6_N4_Mtase PF01555.18 OAG17903.1 - 0.046 13.4 0.0 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 DNA methylase Methyltransf_8 PF05148.15 OAG17903.1 - 0.055 13.3 0.4 0.35 10.7 0.4 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase TPR_1 PF00515.28 OAG17904.1 - 6e-21 73.3 0.7 3.5e-06 26.6 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat STI1 PF17830.1 OAG17904.1 - 3.2e-16 59.0 3.4 8.3e-16 57.7 1.6 2.6 3 0 0 3 3 3 1 STI1 domain TPR_2 PF07719.17 OAG17904.1 - 2.6e-14 52.1 1.8 0.022 14.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG17904.1 - 7.5e-11 41.5 0.1 0.00025 20.6 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 OAG17904.1 - 7.3e-09 36.0 5.8 0.0001 22.7 0.1 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG17904.1 - 7.4e-08 32.6 3.0 0.11 13.4 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG17904.1 - 3e-07 30.1 2.7 0.047 13.9 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG17904.1 - 1e-05 26.1 1.3 0.00021 21.9 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG17904.1 - 2.6e-05 24.3 1.8 0.00015 21.8 0.1 3.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG17904.1 - 0.00011 22.3 0.2 0.41 11.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG17904.1 - 0.00013 21.7 0.4 8.6 6.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG17904.1 - 0.00072 20.0 4.3 0.7 10.7 0.0 5.1 4 2 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG17904.1 - 0.0034 17.6 0.7 0.11 12.8 0.4 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAG17904.1 - 0.0043 17.3 0.8 20 5.6 0.0 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat ProQ PF04352.13 OAG17904.1 - 0.0045 16.9 3.0 0.014 15.3 3.0 1.8 1 0 0 1 1 1 1 ProQ/FINO family DUF982 PF06169.12 OAG17904.1 - 0.045 13.8 0.7 0.36 10.9 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF982) Fis1_TPR_C PF14853.6 OAG17904.1 - 0.046 13.8 0.1 1 9.5 0.2 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF384 PF04064.13 OAG17904.1 - 0.056 13.3 1.5 0.15 11.9 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF384) DUF501 PF04417.12 OAG17904.1 - 0.092 12.6 5.2 1.3 8.8 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF501) TPR_20 PF14561.6 OAG17904.1 - 0.75 10.2 4.6 7.6 6.9 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat STI1 PF17830.1 OAG17905.1 - 7.6e-22 77.0 3.4 1.2e-21 76.4 3.4 1.3 1 0 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 OAG17905.1 - 1.9e-08 33.8 7.3 0.00051 19.7 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG17905.1 - 8.8e-06 25.5 3.6 0.072 13.2 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG17905.1 - 6.2e-05 22.6 2.0 0.0076 15.9 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 OAG17905.1 - 0.00038 20.4 2.5 0.24 11.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG17905.1 - 0.0031 17.8 0.4 0.5 10.7 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Trypan_PARP PF05887.11 OAG17905.1 - 0.0093 15.9 13.1 0.014 15.3 13.1 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 OAG17905.1 - 0.031 13.5 3.1 0.041 13.1 3.1 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 TPR_10 PF13374.6 OAG17905.1 - 0.077 12.9 0.3 2.6 8.0 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3391 PF11871.8 OAG17905.1 - 0.15 12.6 2.4 0.24 11.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) GTA_holin_3TM PF11351.8 OAG17905.1 - 0.72 10.4 2.4 1.5 9.4 1.1 1.9 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release FolB PF02152.18 OAG17906.1 - 7.5e-32 110.2 0.2 3.7e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.18 OAG17907.1 - 1.9e-191 636.1 0.0 2.3e-191 635.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 OAG17907.1 - 0.13 12.4 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO C2 PF00168.30 OAG17909.1 - 1.3e-78 259.9 0.0 5.3e-21 74.8 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 OAG17909.1 - 5.5e-05 22.7 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain PTR2 PF00854.21 OAG17911.1 - 1.3e-79 267.9 8.3 1.7e-79 267.5 8.3 1.1 1 0 0 1 1 1 1 POT family LETM1 PF07766.13 OAG17911.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein ATP-synt_C PF00137.21 OAG17913.1 - 1.7e-35 121.1 35.0 3.9e-22 78.4 15.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tetraspanin PF00335.20 OAG17913.1 - 5 6.8 7.0 8.9 6.0 7.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Ribosomal_L7Ae PF01248.26 OAG17914.1 - 5.7e-27 93.3 0.0 6.6e-27 93.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAG17914.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OAG17914.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF5082 PF16888.5 OAG17914.1 - 0.071 13.4 0.6 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1996 PF09362.10 OAG17915.1 - 1.7e-80 270.4 0.9 2.7e-80 269.8 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAG17915.1 - 9.5e-15 54.6 6.7 9.5e-15 54.6 6.7 2.6 3 0 0 3 3 3 1 WSC domain Tachystatin_A PF11406.8 OAG17915.1 - 0.031 14.4 0.2 0.1 12.7 0.2 1.9 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A GFO_IDH_MocA PF01408.22 OAG17917.1 - 9.6e-23 81.3 0.1 1.5e-22 80.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 OAG17917.1 - 0.0015 19.1 0.3 0.0051 17.4 0.0 2.1 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 OAG17917.1 - 0.044 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 OAG17920.1 - 2.4e-48 165.1 0.0 4.4e-48 164.2 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG17920.1 - 2e-26 93.2 0.0 3.4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG17920.1 - 0.0058 15.8 0.1 0.017 14.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG17920.1 - 0.0091 15.6 0.1 0.027 14.1 0.1 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG17920.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG17920.1 - 0.018 15.2 0.1 0.054 13.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 OAG17920.1 - 0.026 14.8 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 OAG17920.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAG17920.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG17920.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG17920.1 - 0.18 11.0 0.1 0.39 9.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family RRM_1 PF00076.22 OAG17921.1 - 3.2e-57 190.3 0.0 1.3e-21 76.2 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG17921.1 - 3.9e-09 36.3 0.0 0.002 17.9 0.0 4.2 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG17921.1 - 6e-07 29.1 0.0 0.093 12.3 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG17921.1 - 0.00032 20.8 0.1 0.74 10.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAG17921.1 - 0.00049 20.0 0.0 13 5.9 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 OAG17921.1 - 0.0017 18.5 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain Cas_Cas2CT1978 PF09707.10 OAG17921.1 - 0.018 15.1 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) ZinT PF09223.11 OAG17921.1 - 0.085 12.7 0.5 1 9.2 0.0 2.4 2 1 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Med2 PF11214.8 OAG17922.1 - 0.039 14.1 0.9 0.039 14.1 0.9 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 Focal_AT PF03623.13 OAG17922.1 - 0.11 12.4 0.7 0.2 11.7 0.7 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region CCDC53 PF10152.9 OAG17922.1 - 1.4 9.3 19.1 2.2 8.7 3.9 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SPATA3 PF15662.5 OAG17922.1 - 7.1 7.2 16.9 1.1 9.9 7.8 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family SurE PF01975.17 OAG17923.1 - 1.1e-53 181.9 0.0 1.5e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_5 PF08323.11 OAG17923.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Starch synthase catalytic domain adh_short_C2 PF13561.6 OAG17924.1 - 3.6e-52 177.2 0.3 5e-52 176.8 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG17924.1 - 5e-44 150.1 1.6 6e-44 149.8 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG17924.1 - 4.6e-12 46.2 0.3 6e-12 45.8 0.3 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OAG17924.1 - 0.025 14.6 0.3 0.052 13.6 0.3 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2507 PF10702.9 OAG17924.1 - 0.087 12.8 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) GATA PF00320.27 OAG17925.1 - 0.0017 17.9 1.9 0.47 10.1 0.2 2.6 2 0 0 2 2 2 2 GATA zinc finger Zn_clus PF00172.18 OAG17925.1 - 0.053 13.6 13.3 0.16 12.1 13.3 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 OAG17926.1 - 1.2e-17 63.4 0.1 1.6e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.17 OAG17927.1 - 8.8e-106 353.3 5.3 1.4e-105 352.7 5.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAG17927.1 - 7.7e-47 159.4 0.5 2.4e-46 157.8 0.5 1.9 1 0 0 1 1 1 1 DAK2 domain Ribosomal_60s PF00428.19 OAG17927.1 - 0.064 13.9 1.5 0.88 10.2 0.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1442 PF07279.11 OAG17927.1 - 0.18 11.1 4.3 0.4 9.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) DUF1749 PF08538.10 OAG17928.1 - 1.4e-87 293.6 0.0 1.6e-87 293.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAG17928.1 - 0.00018 22.2 0.0 0.00038 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG17928.1 - 0.014 14.7 0.0 0.086 12.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 YjeF_N PF03853.15 OAG17929.1 - 6.2e-41 140.1 0.0 9.8e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 OAG17929.1 - 5.7e-07 30.4 1.6 5.7e-07 30.4 1.6 2.3 2 0 0 2 2 2 1 FDF domain Hamartin PF04388.12 OAG17929.1 - 0.064 11.9 11.5 0.083 11.6 11.5 1.2 1 0 0 1 1 1 0 Hamartin protein Transglut_core PF01841.19 OAG17930.1 - 1.4e-13 51.3 0.0 2.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OAG17930.1 - 0.0051 16.3 0.0 0.13 11.8 0.0 2.5 1 1 0 1 1 1 1 Transglutaminase-like domain DUF1658 PF07871.11 OAG17930.1 - 0.012 15.5 0.8 0.012 15.5 0.8 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1658) ResB PF05140.14 OAG17930.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 ResB-like family Zn_clus PF00172.18 OAG17931.1 - 0.00059 19.9 12.3 0.0011 19.0 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 OAG17931.1 - 0.00084 18.8 0.1 0.00084 18.8 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone domain CHZ Cyclin_N PF00134.23 OAG17932.1 - 1.1e-44 151.3 0.3 2.2e-44 150.3 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG17932.1 - 1.9e-33 115.1 0.1 3.7e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CENP-Q PF13094.6 OAG17932.1 - 0.44 10.7 7.1 1.8 8.8 7.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LSM PF01423.22 OAG17933.1 - 9.4e-19 66.9 0.1 1.2e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kinetochor_Ybp2 PF08568.10 OAG17934.1 - 6.7e-139 464.2 0.3 7.5e-139 464.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Zn_clus PF00172.18 OAG17935.1 - 1.3e-05 25.2 10.5 2.4e-05 24.3 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG17935.1 - 9.7e-05 21.5 0.3 0.00031 19.9 0.3 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain WD40_alt PF14077.6 OAG17935.1 - 0.22 11.4 0.6 0.66 9.9 0.6 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif AA_permease PF00324.21 OAG17936.1 - 6.9e-73 245.9 16.4 8.4e-73 245.6 16.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG17936.1 - 2.4e-20 72.8 20.4 4.5e-20 71.9 20.4 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG17937.1 - 4e-30 104.8 5.1 4.8e-30 104.6 5.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG17937.1 - 8.5e-09 34.7 3.5 1.1e-08 34.4 3.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1627 PF07789.12 OAG17937.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) DUF1754 PF08555.10 OAG17938.1 - 1.6e-16 60.9 11.1 1.6e-16 60.9 11.1 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4778 PF16008.5 OAG17938.1 - 0.13 12.3 4.2 0.15 12.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CAML PF14963.6 OAG17938.1 - 2.6 8.1 5.0 3.2 7.8 5.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF2956 PF11169.8 OAG17938.1 - 8.3 6.7 10.7 12 6.2 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) GAF_2 PF13185.6 OAG17939.1 - 4e-14 53.1 0.1 1.2e-13 51.6 0.1 1.7 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 OAG17939.1 - 2.4e-08 34.7 0.0 3.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OAG17939.1 - 0.05 14.0 0.0 0.23 11.8 0.0 1.8 1 1 1 2 2 2 0 GAF domain AlaDh_PNT_C PF01262.21 OAG17939.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DSPn PF14671.6 OAG17940.1 - 9.6e-42 142.8 0.0 3e-39 134.7 0.0 2.4 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAG17940.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG17940.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG17940.1 - 0.16 12.0 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 OAG17940.1 - 0.21 11.2 0.1 0.4 10.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SET PF00856.28 OAG17941.1 - 0.0015 19.0 0.0 0.0036 17.7 0.0 1.7 1 1 0 1 1 1 1 SET domain Cortex-I_coil PF09304.10 OAG17941.1 - 0.21 11.8 2.2 0.22 11.7 0.7 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil Fungal_trans PF04082.18 OAG17942.1 - 1.8e-36 125.5 0.6 3.5e-36 124.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG17942.1 - 3.4e-09 36.7 11.5 6.2e-09 35.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 OAG17942.1 - 0.054 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF4635 PF15466.6 OAG17942.1 - 0.14 11.7 0.4 0.33 10.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) TFIIA PF03153.13 OAG17942.1 - 0.17 11.8 8.9 0.29 11.1 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAG17942.1 - 0.32 10.6 12.4 0.6 9.7 12.4 1.3 1 0 0 1 1 1 0 Spt20 family HrpB7 PF09486.10 OAG17942.1 - 0.64 10.4 0.0 0.64 10.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) KTI12 PF08433.10 OAG17943.1 - 2.3e-86 289.6 0.0 2.6e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FAM199X PF15814.5 OAG17944.1 - 0.37 9.8 3.7 0.36 9.8 3.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF3431 PF11913.8 OAG17946.1 - 7.6e-90 300.4 0.3 2.3e-89 298.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) TrpP PF17099.5 OAG17946.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan transporter TrpP PLDc_2 PF13091.6 OAG17947.1 - 7.3e-17 61.5 0.0 1.1e-06 28.6 0.0 4.5 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAG17947.1 - 8.5e-12 44.7 1.4 2.4e-05 24.3 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.14 OAG17948.1 - 9.1e-35 118.3 0.0 1.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_19 PF12844.7 OAG17948.1 - 1.9e-05 24.6 0.1 6.6e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 OAG17948.1 - 0.0038 17.3 0.1 0.0067 16.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix zf-C2H2 PF00096.26 OAG17949.1 - 8.8e-09 35.4 30.0 0.044 14.3 0.3 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG17949.1 - 1.7e-07 31.5 35.9 0.014 16.1 0.2 6.8 7 0 0 7 7 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG17949.1 - 0.00012 22.4 3.8 0.011 16.1 0.4 6.3 6 0 0 6 6 6 2 Zinc-finger double domain zf-BED PF02892.15 OAG17949.1 - 0.0039 17.2 0.2 0.0039 17.2 0.2 3.6 3 1 0 3 3 3 1 BED zinc finger zf-C2H2_12 PF18658.1 OAG17949.1 - 0.25 10.9 4.2 0.13 11.8 0.5 2.4 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAG17949.1 - 0.3 11.4 26.5 0.98 9.8 5.7 4.5 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OAG17949.1 - 0.65 9.8 4.1 0.47 10.3 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OAG17949.1 - 0.78 9.8 16.1 0.26 11.3 3.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 OAG17949.1 - 1.7 9.2 14.3 4.1 7.9 1.5 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 OAG17949.1 - 3.1 7.7 9.6 36 4.3 0.1 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 OAG17949.1 - 7.8 7.3 17.7 11 6.8 1.3 3.3 3 0 0 3 3 3 0 zinc-ribbon family Rhomboid PF01694.22 OAG17950.1 - 1e-37 129.5 6.2 1e-37 129.5 6.2 1.8 2 0 0 2 2 2 1 Rhomboid family AXIN1_TNKS_BD PF16646.5 OAG17950.1 - 0.13 13.2 0.7 0.3 12.0 0.7 1.6 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain TMEM43 PF07787.12 OAG17950.1 - 9.3 5.5 5.8 0.64 9.4 0.7 1.6 2 0 0 2 2 2 0 Transmembrane protein 43 Dynamin_N PF00350.23 OAG17951.1 - 2.8e-15 56.8 0.1 5.1e-14 52.7 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAG17951.1 - 2.9e-10 40.2 0.0 4.7e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase zf-rbx1 PF12678.7 OAG17951.1 - 1e-07 32.1 0.6 2.1e-07 31.1 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG17951.1 - 6.7e-07 29.5 1.8 6.7e-07 29.5 1.8 2.5 3 0 0 3 3 2 1 Ring finger domain GTP_EFTU PF00009.27 OAG17951.1 - 1.8e-05 24.4 0.6 0.00026 20.6 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-C3HC4 PF00097.25 OAG17951.1 - 0.00014 21.7 0.7 0.00026 20.8 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG17951.1 - 0.00043 20.2 1.6 0.0012 18.8 1.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG17951.1 - 0.00089 19.0 1.6 0.00089 19.0 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG17951.1 - 0.002 17.9 0.3 0.0058 16.5 0.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2921 PF11145.8 OAG17951.1 - 0.0032 15.4 0.2 0.2 9.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2921) DUF2205 PF10224.9 OAG17951.1 - 0.0043 17.0 0.4 0.012 15.6 0.4 1.7 1 0 0 1 1 1 1 Short coiled-coil protein zf-RING_11 PF17123.5 OAG17951.1 - 0.0048 16.6 4.5 0.045 13.5 0.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OAG17951.1 - 0.0049 16.9 0.3 0.018 15.1 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAG17951.1 - 0.0078 15.8 0.5 0.016 14.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type IIGP PF05049.13 OAG17951.1 - 0.046 12.8 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PQ-loop PF04193.14 OAG17951.1 - 0.07 12.9 0.1 0.07 12.9 0.1 2.8 2 1 1 3 3 3 0 PQ loop repeat cobW PF02492.19 OAG17951.1 - 0.085 12.4 0.3 1.2 8.8 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-C3HC4_3 PF13920.6 OAG17951.1 - 0.12 12.3 4.9 0.031 14.1 1.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_29 PF13555.6 OAG17951.1 - 0.21 11.4 0.4 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-ANAPC11 PF12861.7 OAG17951.1 - 0.27 11.3 1.0 0.61 10.2 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAS PF13851.6 OAG17951.1 - 2 7.7 6.0 8.2 5.7 0.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Snf7 PF03357.21 OAG17952.1 - 3.1e-23 82.3 26.7 2.3e-22 79.4 22.8 2.8 1 1 1 2 2 2 1 Snf7 YlqD PF11068.8 OAG17952.1 - 0.024 15.0 9.0 0.47 10.8 1.1 2.1 2 0 0 2 2 2 0 YlqD protein DUF3958 PF13125.6 OAG17952.1 - 2.5 8.4 11.7 0.17 12.1 4.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) PP2C PF00481.21 OAG17953.1 - 9.2e-64 215.5 0.1 1e-51 176.1 0.2 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C CBS PF00571.28 OAG17954.1 - 2.1e-22 79.3 8.1 1.7e-08 34.8 0.1 4.5 5 0 0 5 5 5 3 CBS domain Amino_oxidase PF01593.24 OAG17957.1 - 3e-45 155.4 0.1 3.6e-44 151.8 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG17957.1 - 4.1e-14 52.6 0.1 1e-13 51.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG17957.1 - 1.4e-06 27.8 0.2 5.5e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG17957.1 - 9.7e-06 24.9 0.5 6.5e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 OAG17957.1 - 2.5e-05 24.7 2.5 0.00011 22.6 0.4 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG17957.1 - 2.8e-05 23.9 0.1 9.7e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG17957.1 - 8e-05 22.0 0.9 0.00016 21.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG17957.1 - 0.00023 20.5 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG17957.1 - 0.00028 19.7 0.1 0.00055 18.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG17957.1 - 0.00064 19.7 0.1 0.43 10.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAG17957.1 - 0.00094 18.5 0.1 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG17957.1 - 0.028 13.8 1.7 0.04 13.2 1.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAG17957.1 - 0.041 13.8 0.3 0.094 12.6 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG17957.1 - 0.042 14.3 0.8 0.1 13.1 0.8 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 OAG17957.1 - 0.049 12.7 0.7 0.091 11.8 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG17957.1 - 0.16 11.2 0.2 0.34 10.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG17957.1 - 0.19 10.7 0.8 0.48 9.4 0.7 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DUF4272 PF14094.6 OAG17958.1 - 0.17 11.1 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) EstA_Ig_like PF18435.1 OAG17959.1 - 0.026 14.7 0.0 0.19 11.9 0.0 2.1 3 0 0 3 3 3 0 Esterase Ig-like N-terminal domain NPBW PF15180.6 OAG17960.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Neuropeptides B and W DNA_ligase_A_N PF04675.14 OAG17961.1 - 1.3e-43 149.3 0.0 2.6e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 OAG17961.1 - 2.8e-42 144.7 0.3 7e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 OAG17961.1 - 5e-21 74.9 0.1 3.6e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 OAG17961.1 - 1.2e-16 61.5 0.0 2.6e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 OAG17961.1 - 1.4e-14 54.5 0.0 4.2e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 OAG17961.1 - 3.5e-09 36.8 0.3 0.0044 17.3 0.0 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 OAG17961.1 - 1.9e-08 34.5 0.1 0.00017 21.9 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG17961.1 - 0.00068 19.5 0.1 0.062 13.3 0.1 2.5 2 0 0 2 2 2 1 twin BRCT domain Bac_globin PF01152.21 OAG17961.1 - 0.034 14.3 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial-like globin RTT107_BRCT_5 PF16770.5 OAG17961.1 - 0.056 13.3 0.0 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DNA_ligase_IV PF11411.8 OAG17961.1 - 0.11 12.6 0.8 0.28 11.4 0.8 1.6 1 0 0 1 1 1 0 DNA ligase IV TFIIIC_delta PF12657.7 OAG17961.1 - 0.5 10.3 2.1 6.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term EF-hand_4 PF12763.7 OAG17962.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Cupin_8 PF13621.6 OAG17963.1 - 3e-65 220.5 0.3 3.5e-65 220.2 0.3 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG17963.1 - 5.7e-05 22.7 0.0 0.0046 16.5 0.0 2.7 3 0 0 3 3 3 2 Cupin superfamily protein Peptidase_S26 PF10502.9 OAG17964.1 - 6.7e-06 25.9 0.0 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 zf-RING_2 PF13639.6 OAG17965.1 - 1.1e-07 32.0 2.0 1.8e-07 31.4 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG17965.1 - 3e-06 27.4 3.2 7e-06 26.2 3.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG17965.1 - 3e-05 23.7 2.8 5.7e-05 22.8 2.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OAG17965.1 - 3.6e-05 23.3 2.9 6.1e-05 22.6 2.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 OAG17965.1 - 9.7e-05 22.2 1.2 0.00016 21.5 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG17965.1 - 0.00011 22.2 3.8 0.00017 21.5 3.8 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG17965.1 - 0.00034 20.6 2.0 0.00064 19.7 2.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG17965.1 - 0.00042 20.1 2.0 0.00064 19.5 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OAG17965.1 - 0.0083 16.3 1.8 0.016 15.3 1.8 1.5 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 OAG17965.1 - 0.3 11.1 3.9 0.47 10.4 3.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 OAG17965.1 - 0.57 10.3 3.3 1.4 9.1 3.3 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 OAG17966.1 - 1e-07 32.2 1.6 1.8e-07 31.4 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG17966.1 - 8e-06 25.5 3.6 1.4e-05 24.7 3.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG17966.1 - 1.1e-05 25.2 1.2 1.7e-05 24.5 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG17966.1 - 1.2e-05 24.8 0.6 2.3e-05 23.9 0.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 OAG17966.1 - 1.7e-05 25.0 0.4 3.7e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG17966.1 - 2.4e-05 24.2 0.6 4.9e-05 23.3 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG17966.1 - 0.00013 21.8 0.5 0.00021 21.1 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG17966.1 - 0.0017 18.4 0.3 0.0031 17.5 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAG17966.1 - 0.003 17.5 0.6 0.0053 16.7 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 OAG17966.1 - 0.039 14.0 1.6 0.063 13.3 1.6 1.3 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 OAG17966.1 - 0.091 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OAG17966.1 - 0.1 12.5 0.9 0.18 11.8 0.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 OAG17966.1 - 0.13 12.4 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 OAG17966.1 - 0.16 11.9 0.4 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG17966.1 - 0.16 11.9 1.1 0.28 11.1 1.1 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 OAG17966.1 - 0.19 11.6 1.0 0.36 10.7 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Snapin_Pallidin PF14712.6 OAG17966.1 - 1.5 9.3 5.1 0.28 11.6 1.0 1.8 2 0 0 2 2 2 0 Snapin/Pallidin COPIIcoated_ERV PF07970.12 OAG17967.1 - 3.7e-32 112.0 0.0 5.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG17967.1 - 1.2e-20 73.7 0.0 2.2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NAD_binding_10 PF13460.6 OAG17970.1 - 1.9e-06 27.9 0.0 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG17970.1 - 6.1e-05 22.7 0.0 0.00024 20.8 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG17970.1 - 0.0021 18.3 0.0 0.0059 16.9 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG17970.1 - 0.035 14.2 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Homeodomain PF00046.29 OAG17971.1 - 8.6e-13 47.9 3.5 1.9e-12 46.9 3.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG17971.1 - 0.063 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Piwi PF02171.17 OAG17972.1 - 9.9e-44 149.8 0.1 1.4e-43 149.3 0.1 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG17972.1 - 0.0031 18.1 0.2 0.0096 16.5 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG17972.1 - 0.03 14.0 0.1 0.09 12.5 0.1 1.8 1 0 0 1 1 1 0 Argonaute linker 1 domain Arf PF00025.21 OAG17973.1 - 5.4e-68 227.9 1.9 6.5e-36 123.4 0.3 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAG17973.1 - 3.4e-10 39.6 0.5 4.3e-06 26.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAG17973.1 - 6.1e-10 38.8 0.4 6.6e-09 35.4 0.4 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG17973.1 - 1.9e-09 37.8 0.1 4.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAG17973.1 - 4.9e-09 35.9 0.1 9.7e-09 34.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAG17973.1 - 3.9e-07 29.8 0.1 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 OAG17973.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG17973.1 - 0.075 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Glyco_transf_8 PF01501.20 OAG17974.1 - 4.3e-15 56.0 0.0 7.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 OAG17975.1 - 2.2e-55 184.6 0.2 7.2e-19 67.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Qn_am_d_aIII PF09099.10 OAG17975.1 - 0.2 12.0 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III PMI_typeI PF01238.21 OAG17976.1 - 6.3e-147 489.6 0.0 7.4e-147 489.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cas_TM1802 PF09484.10 OAG17976.1 - 0.004 16.0 0.1 0.0081 15.0 0.1 1.3 1 1 0 1 1 1 1 CRISPR-associated protein TM1802 (cas_TM1802) DUF3813 PF12758.7 OAG17976.1 - 0.016 15.5 2.6 0.034 14.5 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Talin_middle PF09141.10 OAG17976.1 - 0.099 12.7 0.3 0.18 11.9 0.3 1.4 1 0 0 1 1 1 0 Talin, middle domain DUF1325 PF07039.11 OAG17977.1 - 1.1e-32 112.9 0.0 1.8e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain SIKE PF05769.11 OAG17978.1 - 6.4e-06 26.2 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 SIKE family ADIP PF11559.8 OAG17978.1 - 2 8.5 6.6 1.2 9.2 0.3 3.0 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 OAG17978.1 - 4.5 7.1 11.0 2.7 7.8 0.0 3.7 4 0 0 4 4 4 0 Septum formation initiator AMP-binding PF00501.28 OAG17979.1 - 1.6e-98 330.1 0.0 2e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG17979.1 - 1.2e-13 51.8 0.0 3.1e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDUF_B7 PF05676.13 OAG17980.1 - 9.6e-28 95.7 6.7 1.1e-27 95.5 6.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_2 PF12796.7 OAG17981.1 - 4.2e-13 49.7 0.1 1.8e-05 25.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG17981.1 - 4.1e-10 40.0 0.1 1.2e-05 25.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG17981.1 - 1.7e-07 30.9 0.2 0.16 12.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG17981.1 - 4.1e-07 30.2 0.5 0.00033 20.9 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG17981.1 - 5.3e-07 29.8 0.2 0.17 12.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 OAG17981.1 - 2e-05 24.4 0.5 0.00016 21.5 0.1 2.6 2 1 0 2 2 2 1 KilA-N domain MbeD_MobD PF04899.12 OAG17981.1 - 0.066 13.3 1.8 0.24 11.5 0.3 2.6 2 0 0 2 2 2 0 MbeD/MobD like Selenoprotein_S PF06936.11 OAG17981.1 - 0.72 9.6 3.5 1.4 8.7 3.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) EamA PF00892.20 OAG17982.1 - 1.3e-08 35.1 26.2 1.1e-07 32.1 1.8 2.6 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 OAG17982.1 - 0.0036 16.9 0.2 0.014 14.9 0.2 1.9 1 1 0 1 1 1 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 OAG17982.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter DUF4579 PF15158.6 OAG17982.1 - 0.017 14.9 0.6 0.085 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) TPT PF03151.16 OAG17982.1 - 5.5 6.2 10.3 1.1 8.5 1.1 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family PTPA PF03095.15 OAG17983.1 - 7.1e-111 370.4 0.0 8.4e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1771 PF08590.10 OAG17984.1 - 2.3e-23 82.3 11.5 4.8e-23 81.3 11.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAG17984.1 - 3.3e-12 46.6 0.5 1e-11 45.0 0.5 1.9 1 0 0 1 1 1 1 Smr domain GRP PF07172.11 OAG17984.1 - 5.4 7.8 17.0 2.2 9.0 14.1 1.9 2 0 0 2 2 2 0 Glycine rich protein family Use1 PF09753.9 OAG17985.1 - 8.9e-17 61.6 0.7 1.3e-16 61.1 0.7 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.21 OAG17985.1 - 0.018 14.8 5.0 0.021 14.6 0.0 3.1 4 0 0 4 4 4 0 Synaptobrevin Syntaxin-6_N PF09177.11 OAG17985.1 - 0.15 12.7 4.4 0.75 10.4 1.6 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2730 PF10805.8 OAG17985.1 - 1.3 9.2 3.6 0.46 10.6 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) zf-C2H2_4 PF13894.6 OAG17987.1 - 2 9.5 7.3 27 6.0 0.5 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG17987.1 - 2.6 8.7 11.0 1.1 9.9 3.0 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type XAP5 PF04921.14 OAG17987.1 - 9 6.0 7.6 0.88 9.4 1.8 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator GSHPx PF00255.19 OAG17988.1 - 1.8e-37 127.2 0.1 2.5e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OAG17988.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 OAG17988.1 - 0.048 13.4 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Redoxin PI-PLC-X PF00388.19 OAG17990.1 - 2.2e-63 212.2 0.0 3.6e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG17990.1 - 2.2e-41 140.8 0.0 4.2e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 OAG17990.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_like PF09279.11 OAG17990.1 - 0.0056 17.1 0.0 0.09 13.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1160 PF06648.11 OAG17990.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Acyl-CoA_dh_1 PF00441.24 OAG17990.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase_6 PF13344.6 OAG17996.1 - 3.1e-23 81.8 0.0 5.9e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG17996.1 - 5.5e-14 52.0 0.0 2.6e-13 49.8 0.0 2.2 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG17996.1 - 0.091 13.0 0.0 14 5.9 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG17996.1 - 0.19 11.8 0.0 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 OAG17997.1 - 1.9e-24 86.0 0.9 9.5e-22 77.2 0.6 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG17997.1 - 6.8e-20 71.3 0.7 5.1e-19 68.4 0.2 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG17997.1 - 0.00075 19.6 0.0 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Retinal PF15449.6 OAG18000.1 - 2.7 5.7 12.8 3 5.5 12.8 1.0 1 0 0 1 1 1 0 Retinal protein Actin PF00022.19 OAG18001.1 - 8.8e-113 377.0 0.0 6.1e-112 374.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG18001.1 - 0.034 13.0 0.0 0.14 10.9 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein Ribosomal_L5e PF17144.4 OAG18002.1 - 3.1e-80 267.9 0.3 5.1e-80 267.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAG18002.1 - 1.8e-36 125.0 7.6 1.8e-36 125.0 7.6 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3135 PF11333.8 OAG18003.1 - 0.13 12.5 0.1 3.2 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) NAD_kinase PF01513.21 OAG18004.1 - 4.7e-80 268.9 0.0 6.8e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase InvH PF04741.12 OAG18004.1 - 0.31 11.0 1.4 0.75 9.7 0.5 2.0 1 1 1 2 2 2 0 InvH outer membrane lipoprotein Spermine_synth PF01564.17 OAG18005.1 - 1.1e-70 236.8 0.0 2.5e-70 235.7 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OAG18005.1 - 1.2e-24 86.0 0.2 2.2e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OAG18005.1 - 0.00054 20.6 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG18005.1 - 0.0041 17.8 0.2 0.022 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG18005.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG18006.1 - 9e-09 35.9 0.1 2.2e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG18006.1 - 1.1e-05 26.0 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG18006.1 - 0.0006 20.5 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG18006.1 - 0.0055 16.5 0.4 0.016 15.0 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG18006.1 - 0.051 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Coatomer_E PF04733.14 OAG18007.1 - 3.2e-59 200.7 8.9 4e-59 200.4 8.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.6 OAG18007.1 - 2.3e-05 24.9 6.5 0.072 13.9 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG18007.1 - 2.5e-05 24.7 16.2 0.0029 18.1 1.8 3.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG18007.1 - 5.9e-05 22.9 9.4 0.015 15.4 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG18007.1 - 0.00041 20.1 0.9 0.13 12.1 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG18007.1 - 0.00042 20.3 0.6 4.1 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG18007.1 - 0.00074 19.8 8.6 0.013 15.8 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG18007.1 - 0.001 19.7 9.5 0.036 14.7 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG18007.1 - 0.0015 18.2 0.5 0.12 12.1 0.0 3.5 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 OAG18007.1 - 0.0036 17.5 0.7 0.33 11.2 0.1 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAG18007.1 - 0.026 15.1 9.0 0.053 14.2 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG18007.1 - 0.042 14.0 1.9 0.8 9.9 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG18007.1 - 0.082 13.3 0.2 2 9.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG18007.1 - 0.3 11.0 3.2 2.4 8.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Tubulin PF00091.25 OAG18008.1 - 1.8e-67 227.4 0.0 2.7e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG18008.1 - 1.1e-45 154.9 0.9 3e-45 153.4 0.2 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain GDPD PF03009.17 OAG18008.1 - 1.4e-31 110.2 0.0 3.4e-31 108.9 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.9 OAG18008.1 - 3.1e-06 27.5 0.1 6.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAG18008.1 - 0.0024 17.6 0.0 0.058 13.1 0.0 2.3 2 0 0 2 2 2 1 Tubulin domain GDPD_2 PF13653.6 OAG18008.1 - 0.015 15.8 0.2 0.038 14.4 0.2 1.8 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PilJ PF13675.6 OAG18009.1 - 0.099 12.7 0.1 1.1 9.4 0.4 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Erp_C PF06780.11 OAG18009.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Erp protein C-terminus PEP_mutase PF13714.6 OAG18010.1 - 1.6e-46 158.7 0.1 1.8e-46 158.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG18010.1 - 3.8e-19 68.6 0.2 5.1e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OAG18010.1 - 0.0099 15.3 0.2 0.07 12.5 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase MR_MLE_C PF13378.6 OAG18010.1 - 0.02 14.4 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like Fungal_trans PF04082.18 OAG18012.1 - 1.4e-11 43.9 0.1 3.1e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18012.1 - 2.8e-09 36.9 8.0 4.7e-09 36.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.6 OAG18012.1 - 4.7 5.0 13.1 8.6 4.1 10.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 OAG18012.1 - 8.7 6.2 18.5 17 5.3 18.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 OAG18014.1 - 1.6 7.2 25.9 2 6.9 25.9 1.1 1 0 0 1 1 1 0 Macoilin family Med15 PF09606.10 OAG18014.1 - 4.3 5.9 55.9 6.1 5.4 55.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1713 PF08213.11 OAG18015.1 - 1.8e-11 43.7 23.1 3.7e-11 42.7 23.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Tis11B_N PF04553.12 OAG18015.1 - 0.19 12.3 2.5 0.3 11.6 1.1 2.0 2 0 0 2 2 2 0 Tis11B like protein, N terminus Mito_fiss_reg PF05308.11 OAG18016.1 - 3.4 7.7 9.3 4.2 7.4 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OAG18016.1 - 5 6.5 9.3 5.4 6.4 9.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal G-alpha PF00503.20 OAG18017.1 - 4.3e-106 355.1 1.6 5.1e-106 354.8 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG18017.1 - 1.1e-13 51.0 0.4 6.6e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG18017.1 - 6.5e-06 25.7 1.2 0.00051 19.5 0.4 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG18017.1 - 0.057 13.6 0.4 3.3 8.0 0.0 2.7 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2985 PF11204.8 OAG18017.1 - 0.073 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) HET PF06985.11 OAG18018.1 - 2e-07 31.5 0.0 2e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 OAG18019.1 - 1.4e-09 37.8 0.5 1.4e-09 37.8 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG18019.1 - 4e-08 33.3 0.0 7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG18019.1 - 0.0082 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Hexapep PF00132.24 OAG18021.1 - 2.6e-12 46.0 8.5 7.3e-05 22.3 2.9 5.1 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG18021.1 - 8.6e-08 31.8 8.0 0.0013 18.5 0.0 4.2 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAG18021.1 - 0.034 13.1 0.3 0.042 12.8 0.3 1.1 1 0 0 1 1 1 0 L-fucokinase Fungal_trans PF04082.18 OAG18023.1 - 6.2e-23 81.2 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG18023.1 - 1.3e-08 34.8 15.3 0.00042 20.6 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG18023.1 - 7.8e-07 29.2 13.6 2.7e-06 27.5 7.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG18023.1 - 6.2e-05 23.5 14.1 0.02 15.7 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Cytochrom_C1 PF02167.15 OAG18023.1 - 0.097 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C1 family MscS_porin PF12795.7 OAG18025.1 - 0.00084 19.0 38.1 0.00084 19.0 38.1 4.9 2 1 2 4 4 4 1 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 OAG18025.1 - 0.0019 18.1 56.0 0.062 13.1 31.6 3.9 1 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 OAG18025.1 - 0.0021 18.1 11.6 0.0021 18.1 11.6 5.3 4 1 1 5 5 5 2 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OAG18025.1 - 0.0083 16.4 23.9 0.0083 16.4 23.9 5.7 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 OAG18025.1 - 10 6.3 33.6 2.3 8.4 0.1 5.6 4 1 1 5 5 5 0 TolA binding protein trimerisation dCMP_cyt_deam_1 PF00383.23 OAG18028.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Aldo_ket_red PF00248.21 OAG18029.1 - 1.8e-12 47.1 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 OAG18030.1 - 9.7e-52 174.7 1.7 1.9e-51 173.7 1.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.10 OAG18030.1 - 4.3e-49 167.0 0.0 6.4e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Glyco_hydro_72 PF03198.14 OAG18031.1 - 4.2e-133 443.5 7.0 5.2e-133 443.2 7.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAG18031.1 - 7.7e-06 25.5 0.5 9.7e-05 21.9 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG18031.1 - 0.004 16.3 0.3 0.012 14.7 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Syntaxin PF00804.25 OAG18032.1 - 1.3e-21 77.2 5.1 1.3e-21 77.2 5.1 1.7 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 OAG18032.1 - 1.6e-08 34.4 0.2 3.7e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 OAG18032.1 - 0.0013 19.0 4.2 0.0013 19.0 4.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Use1 PF09753.9 OAG18032.1 - 0.0066 16.2 7.3 0.012 15.3 7.3 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF2721 PF11026.8 OAG18032.1 - 0.042 13.7 1.2 0.071 13.0 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) DotU PF09850.9 OAG18032.1 - 0.058 13.1 1.2 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU MCU PF04678.13 OAG18032.1 - 0.18 11.9 3.5 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Orf78 PF06024.12 OAG18032.1 - 0.21 11.9 0.6 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) PBP1_TM PF14812.6 OAG18032.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2951 PF11166.8 OAG18032.1 - 0.59 10.4 5.1 0.18 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4094 PF13334.6 OAG18032.1 - 1.4 9.4 8.8 3.6 8.1 0.0 3.5 2 1 1 4 4 4 0 Domain of unknown function (DUF4094) Cnn_1N PF07989.11 OAG18032.1 - 2.3 8.4 10.1 5.5 7.2 2.3 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CCDC-167 PF15188.6 OAG18032.1 - 2.3 8.6 6.5 51 4.3 0.2 3.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 LPP PF04728.13 OAG18032.1 - 2.4 8.6 5.8 14 6.1 0.4 3.5 3 1 0 3 3 3 0 Lipoprotein leucine-zipper BRCT PF00533.26 OAG18033.1 - 1.1e-09 38.5 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG18033.1 - 4.8e-09 36.0 0.1 1.1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OAG18033.1 - 6.8e-07 29.6 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG18033.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain IGPS PF00218.21 OAG18034.1 - 8.8e-99 329.8 0.0 2.7e-96 321.6 0.0 2.2 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase PRAI PF00697.22 OAG18034.1 - 2.3e-49 167.8 0.6 9.9e-44 149.4 0.2 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 OAG18034.1 - 2.3e-47 161.2 0.1 6e-47 159.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAG18034.1 - 1.3e-06 28.3 0.1 4.5e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 OAG18034.1 - 8.7e-06 25.1 0.4 0.012 14.8 0.1 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 OAG18034.1 - 0.00084 19.2 1.3 0.022 14.6 0.1 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 OAG18034.1 - 0.0015 18.0 0.1 2.2 7.7 0.0 2.6 2 1 0 2 2 2 2 Histidine biosynthesis protein Peripla_BP_2 PF01497.18 OAG18034.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Nup188_C PF18378.1 OAG18035.1 - 4e-142 473.4 0.4 6.1e-142 472.8 0.4 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 OAG18035.1 - 6.4e-56 189.9 0.0 1e-42 146.2 0.0 3.9 3 1 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 HhH-GPD PF00730.25 OAG18037.1 - 5.9e-20 71.7 0.0 1.6e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG18037.1 - 2.1e-06 27.3 0.3 1.9e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif SRRM_C PF15230.6 OAG18037.1 - 5.4 7.6 10.4 16 6.1 10.4 1.7 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus ThiP_synth PF10120.9 OAG18038.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Thiamine-phosphate synthase AT_hook PF02178.19 OAG18039.1 - 0.061 13.2 20.4 0.69 10.0 6.6 2.7 2 0 0 2 2 2 0 AT hook motif RSN1_7TM PF02714.15 OAG18040.1 - 3.8e-87 292.1 24.9 5.8e-87 291.5 24.9 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG18040.1 - 9.2e-26 91.1 1.7 2.5e-14 53.9 0.0 2.8 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG18040.1 - 7.9e-22 77.7 3.0 7.9e-22 77.7 3.0 4.1 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAG18040.1 - 7.2e-13 48.5 0.2 3.1e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2065 PF09838.9 OAG18040.1 - 2.1 8.4 6.1 1.4 9.0 1.3 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) MFS_1 PF07690.16 OAG18043.1 - 5.3e-42 144.0 80.8 6e-38 130.7 55.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG18043.1 - 1.5e-10 40.1 23.0 2.5e-10 39.4 23.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG18043.1 - 2.4e-08 33.3 32.5 2.1e-05 23.6 13.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_tran_28_C PF04101.16 OAG18044.1 - 3.8e-09 36.7 0.1 5.9e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 OAG18044.1 - 1.3e-08 34.1 0.1 2.9e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.16 OAG18046.1 - 7e-29 100.8 34.4 8.9e-29 100.5 34.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NSs PF11073.8 OAG18046.1 - 0.081 12.4 0.1 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Rift valley fever virus non structural protein (NSs) like HATPase_c_3 PF13589.6 OAG18047.1 - 4.3e-16 59.0 0.0 1.1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 OAG18047.1 - 2e-06 27.6 0.2 2.2e-05 24.3 0.1 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 OAG18047.1 - 0.009 16.5 0.0 0.053 14.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 OAG18048.1 - 3.3 7.6 9.4 4 7.3 9.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTB PF00651.31 OAG18049.1 - 8.2e-08 32.5 0.0 2.9e-07 30.7 0.0 1.8 1 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 OAG18050.1 - 3.2e-08 33.8 0.0 2.4e-07 31.0 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain YCII PF03795.14 OAG18051.1 - 2.6e-06 27.7 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Ribonuc_red_lgC PF02867.15 OAG18052.1 - 1.5e-188 627.7 0.0 1.9e-188 627.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAG18052.1 - 6.3e-25 87.0 0.0 1.5e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAG18052.1 - 1e-16 61.2 0.0 3.9e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Prok-E2_B PF14461.6 OAG18052.1 - 0.12 12.1 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family B Ribosomal_L17 PF01196.19 OAG18053.1 - 1.8e-33 115.3 0.2 4.4e-33 114.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 BTB PF00651.31 OAG18054.1 - 8.5e-09 35.6 0.1 3.6e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Dabb PF07876.12 OAG18055.1 - 1.3e-22 80.2 0.2 1.6e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SLH PF00395.20 OAG18055.1 - 0.44 10.6 1.4 0.7 9.9 0.1 2.0 3 0 0 3 3 3 0 S-layer homology domain DUF1761 PF08570.10 OAG18056.1 - 1.9e-28 99.2 3.0 2.1e-28 99.1 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Polysacc_deac_1 PF01522.21 OAG18057.1 - 8.1e-25 87.1 0.0 1.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase COX7C PF02935.16 OAG18057.1 - 0.022 15.0 1.6 0.045 14.0 1.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Polysacc_deac_2 PF04748.13 OAG18057.1 - 0.033 13.4 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Ribonuc_2-5A PF06479.12 OAG18057.1 - 0.066 13.4 0.0 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease 2-5A RELT PF12606.8 OAG18057.1 - 0.75 8.8 0.0 0.75 8.8 0.0 2.5 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 DUF1279 PF06916.13 OAG18058.1 - 3.4e-23 82.0 0.0 5.3e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PNGaseA PF12222.8 OAG18059.1 - 1.1e-171 571.5 5.6 1.8e-171 570.8 5.6 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A EamA PF00892.20 OAG18060.1 - 6.4e-19 68.5 26.3 1.3e-10 41.6 13.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family zf-C3HC4_3 PF13920.6 OAG18061.1 - 0.00024 20.9 14.5 0.00042 20.1 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 OAG18061.1 - 0.019 15.2 6.5 0.041 14.1 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4 PF00097.25 OAG18061.1 - 0.024 14.5 16.0 0.049 13.5 16.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG18061.1 - 0.12 12.8 15.2 0.23 11.9 15.2 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OAG18061.1 - 0.26 11.2 13.0 0.6 10.0 13.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG18061.1 - 0.34 10.9 11.4 0.78 9.8 11.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG18061.1 - 0.58 10.0 17.9 3.6 7.5 17.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG18061.1 - 9.6 6.5 12.7 24 5.2 12.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4201 PF13870.6 OAG18062.1 - 0.019 14.7 5.7 0.081 12.6 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.20 OAG18062.1 - 0.2 11.6 0.1 0.2 11.6 0.1 3.3 3 1 1 4 4 4 0 Prefoldin subunit Sec34 PF04136.15 OAG18062.1 - 1.5 8.7 6.2 0.88 9.4 1.6 3.0 3 1 0 3 3 3 0 Sec34-like family DUF1043 PF06295.12 OAG18062.1 - 2.4 8.2 4.6 12 5.9 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) BRE1 PF08647.11 OAG18062.1 - 4.3 7.5 9.2 0.68 10.1 3.0 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Formyl_trans_N PF00551.19 OAG18063.1 - 3.1e-23 82.5 0.0 4.1e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase DUF1712 PF08217.11 OAG18064.1 - 7.2e-15 54.5 0.0 1.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF2517 PF10725.9 OAG18064.1 - 0.12 12.1 1.7 3.7 7.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) adh_short_C2 PF13561.6 OAG18065.1 - 1.3e-37 129.6 0.4 2.3e-37 128.8 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18065.1 - 4.7e-35 120.8 0.8 9.2e-35 119.9 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.21 OAG18065.1 - 7.9e-17 61.7 0.0 8.1e-12 45.3 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain KR PF08659.10 OAG18065.1 - 1.4e-10 41.3 0.1 3.1e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Med5 PF08689.10 OAG18066.1 - 8.7e-178 593.4 0.0 2e-176 588.9 0.0 2.3 1 1 0 1 1 1 1 Mediator complex subunit Med5 DNA_pack_N PF02500.15 OAG18066.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Aldo_ket_red PF00248.21 OAG18068.1 - 9.4e-36 123.5 0.0 1.4e-33 116.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ELFV_dehydrog PF00208.21 OAG18069.1 - 6e-85 284.8 2.2 7.5e-85 284.5 2.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAG18069.1 - 9.8e-50 167.8 0.0 2.2e-49 166.6 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 OAG18069.1 - 0.012 16.1 0.3 0.029 14.8 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAG18069.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 OAG18069.1 - 0.083 13.3 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Helo_like_N PF17111.5 OAG18070.1 - 1.3e-05 24.6 2.0 2.1e-05 24.0 2.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF3439 PF11921.8 OAG18071.1 - 2.3 8.2 9.5 4.8 7.2 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) adh_short_C2 PF13561.6 OAG18072.1 - 2.2e-55 187.8 0.0 2.9e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18072.1 - 8.4e-43 146.1 0.0 1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG18072.1 - 8.4e-09 35.6 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Coa1 PF08695.10 OAG18075.1 - 4.6e-37 126.3 0.0 5.8e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Neurensin PF14927.6 OAG18076.1 - 0.42 10.3 2.3 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 Neurensin DUF998 PF06197.13 OAG18076.1 - 0.6 9.7 6.8 0.21 11.2 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF981 PF06168.11 OAG18076.1 - 0.87 9.5 8.1 1.3 8.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF997 PF06196.12 OAG18076.1 - 7.1 6.7 6.2 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) HypA PF01155.19 OAG18077.1 - 0.075 13.1 1.2 3.6 7.6 0.1 2.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SspP PF08179.12 OAG18077.1 - 0.3 11.6 3.7 0.8 10.2 0.0 2.7 2 0 0 2 2 2 0 Small acid-soluble spore protein P family Pkinase PF00069.25 OAG18078.1 - 1.2e-13 51.1 0.0 4.5e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18078.1 - 3.2e-09 36.4 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 OAG18078.1 - 2.2e-06 27.8 0.0 1.8e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG18078.1 - 2.1e-05 24.4 4.0 0.11 12.8 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Kinase-like PF14531.6 OAG18078.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 OAG18078.1 - 0.0023 18.3 3.0 0.023 15.1 0.8 3.2 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 OAG18078.1 - 0.012 16.2 0.1 13 6.4 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.20 OAG18078.1 - 0.15 10.6 0.0 0.32 9.5 0.0 1.4 1 1 1 2 2 2 0 Adaptin N terminal region Aim19 PF10315.9 OAG18079.1 - 1.9e-06 28.2 0.2 2.2e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 OAG18080.1 - 1.1e-28 99.5 1.3 1.9e-28 98.8 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 OAG18080.1 - 8.9e-21 73.8 0.9 8.9e-21 73.8 0.9 1.8 2 0 0 2 2 2 1 DnaJ domain Cyto_heme_lyase PF01265.17 OAG18081.1 - 1.1e-42 146.6 12.9 6.2e-38 131.1 1.1 2.9 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase CAP_N PF01213.19 OAG18081.1 - 2.8 7.3 6.4 4.4 6.7 6.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MDD_C PF18376.1 OAG18082.1 - 4.7e-66 222.1 0.1 6.9e-66 221.6 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAG18082.1 - 8.6e-09 35.5 0.8 2.4e-08 34.1 0.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain BTB PF00651.31 OAG18083.1 - 6.1e-10 39.3 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Phage_Gp111 PF07410.11 OAG18083.1 - 0.068 13.7 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein Syntaxin_2 PF14523.6 OAG18084.1 - 1.5e-23 83.1 10.8 1.8e-23 82.8 2.9 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OAG18084.1 - 2e-15 56.5 2.2 3.7e-15 55.7 1.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OAG18084.1 - 1.5e-07 31.3 16.9 3.6e-06 26.8 16.9 2.3 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 OAG18084.1 - 0.0017 18.1 0.5 0.0017 18.1 0.5 2.3 3 0 0 3 3 2 1 Synaptobrevin Nre_C PF04895.12 OAG18084.1 - 0.014 15.3 3.2 0.023 14.6 0.1 2.5 3 0 0 3 3 3 0 Archaeal Nre, C-terminal MCPsignal PF00015.21 OAG18084.1 - 0.016 15.0 5.2 0.34 10.7 0.9 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF883 PF05957.13 OAG18084.1 - 0.068 13.8 17.0 0.09 13.4 0.9 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) LptF_LptG PF03739.14 OAG18084.1 - 0.13 11.1 0.1 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Prominin PF05478.11 OAG18084.1 - 0.19 9.6 8.0 0.55 8.1 8.0 1.7 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 OAG18084.1 - 0.23 11.5 5.1 20 5.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAG18084.1 - 0.41 9.8 9.1 0.89 8.7 6.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein PMC2NT PF08066.12 OAG18084.1 - 0.44 11.3 3.2 0.63 10.8 0.2 2.5 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Orf78 PF06024.12 OAG18084.1 - 0.48 10.7 4.0 0.26 11.6 0.4 2.3 2 1 0 2 2 2 0 Orf78 (ac78) Amnionless PF14828.6 OAG18084.1 - 0.61 8.9 7.3 1.2 7.9 7.2 1.7 1 1 0 1 1 1 0 Amnionless YabA PF06156.13 OAG18084.1 - 1.7 9.3 0.0 1.7 9.3 0.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA YtxH PF12732.7 OAG18084.1 - 3.9 8.1 10.0 0.96 10.0 0.8 3.0 3 0 0 3 3 3 0 YtxH-like protein DUF131 PF01998.17 OAG18084.1 - 4 7.2 5.4 10 5.9 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF131 Ndc1_Nup PF09531.10 OAG18085.1 - 6.6e-169 563.5 0.0 7.4e-169 563.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Asp PF00026.23 OAG18086.1 - 2e-62 211.4 4.0 2.6e-62 211.1 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG18086.1 - 2.9e-09 37.4 3.3 3.3e-09 37.2 1.5 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Ras PF00071.22 OAG18087.1 - 3.6e-55 186.0 0.0 4.2e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG18087.1 - 6.9e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG18087.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG18087.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OAG18087.1 - 0.036 13.8 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 OAG18087.1 - 0.038 13.2 0.1 0.37 10.0 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 OAG18087.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ufd2P_core PF10408.9 OAG18088.1 - 6e-217 722.2 12.5 7.3e-217 721.9 12.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAG18088.1 - 6e-23 80.8 0.5 1.7e-22 79.3 0.5 1.8 1 0 0 1 1 1 1 U-box domain GldM_N PF12081.8 OAG18088.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.9 2 1 1 3 3 3 0 GldM N-terminal domain DUF2203 PF09969.9 OAG18088.1 - 0.22 12.2 9.8 0.16 12.7 0.7 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 OAG18088.1 - 1 9.9 4.4 11 6.7 0.1 3.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal F-box_4 PF15966.5 OAG18089.1 - 3.7e-05 23.6 0.1 8.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 OAG18089.1 - 0.00011 22.0 0.3 0.00022 21.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG18089.1 - 0.00052 19.8 0.7 0.0014 18.5 0.7 1.7 1 0 0 1 1 1 1 F-box domain DNA_pol_A_exo1 PF01612.20 OAG18090.1 - 0.078 12.7 0.1 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 3'-5' exonuclease Tannase PF07519.11 OAG18091.1 - 3e-87 293.5 1.5 3.5e-87 293.3 1.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG18091.1 - 3e-05 23.6 0.1 0.11 12.0 0.1 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG18091.1 - 0.001 18.4 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG18091.1 - 0.069 12.8 0.2 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 OAG18093.1 - 1.1e-49 168.5 0.1 1.6e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18093.1 - 1.8e-37 129.2 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18093.1 - 9.8e-11 41.9 0.1 1.5e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG18093.1 - 0.0012 18.7 0.3 0.0019 18.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG18093.1 - 0.0014 18.2 0.1 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 OAG18093.1 - 0.005 16.2 0.2 0.0085 15.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 OAG18093.1 - 0.036 13.5 0.1 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_25 PF13649.6 OAG18093.1 - 0.041 14.6 0.2 0.089 13.5 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 OAG18093.1 - 0.077 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 OAG18093.1 - 0.086 12.2 0.2 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 OAG18093.1 - 0.1 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tannase PF07519.11 OAG18094.1 - 4.6e-135 451.1 2.4 5.5e-135 450.9 2.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 OAG18096.1 - 2.5e-82 277.2 31.4 2.9e-82 277.0 31.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG18096.1 - 3.4e-13 49.2 35.5 3.3e-09 36.1 13.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Melibiase_2 PF16499.5 OAG18097.1 - 3.7e-39 134.6 0.1 7.3e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG18097.1 - 2.3e-13 50.0 0.6 1.4e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG18097.1 - 0.00081 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Melibiase Gal_mutarotas_3 PF18080.1 OAG18097.1 - 0.041 13.8 1.1 0.076 13.0 1.1 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like fold domain OB_Dis3 PF17849.1 OAG18098.1 - 0.17 11.9 0.5 0.62 10.1 0.1 1.9 1 1 1 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) Glyco_hydro_63 PF03200.16 OAG18099.1 - 8.5e-153 509.6 0.1 3.9e-151 504.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAG18099.1 - 2.5e-56 191.3 0.1 1e-54 186.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAG18099.1 - 0.041 12.7 0.0 0.13 11.0 0.0 1.8 2 1 0 2 2 2 0 Trehalase PRK PF00485.18 OAG18100.1 - 8.8e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG18100.1 - 4.2e-05 24.0 0.0 6.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 OAG18100.1 - 4.6e-05 22.7 0.0 6.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 OAG18100.1 - 0.00015 22.3 0.1 0.0045 17.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG18100.1 - 0.004 17.4 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG18100.1 - 0.0041 17.5 0.5 0.032 14.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAG18100.1 - 0.0058 15.7 0.0 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 OAG18100.1 - 0.0061 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.12 OAG18100.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OAG18100.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAG18100.1 - 0.011 15.5 0.2 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 OAG18100.1 - 0.012 14.9 0.2 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 OAG18100.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 OAG18100.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 OAG18100.1 - 0.028 14.6 0.4 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 OAG18100.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 OAG18100.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 OAG18100.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 OAG18100.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 OAG18100.1 - 0.22 11.2 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-RING_6 PF14835.6 OAG18102.1 - 0.19 11.6 0.1 7.4 6.5 0.0 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Endosulfine PF04667.17 OAG18103.1 - 4.5e-30 103.6 0.2 6.3e-30 103.1 0.2 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 OAG18104.1 - 1.1e-83 279.7 0.0 1.3e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 OAG18105.1 - 8.2e-117 391.1 0.0 1.1e-116 390.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Rad52_Rad22 PF04098.15 OAG18105.1 - 5.7e-59 198.4 0.1 8.8e-59 197.8 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SKG6 PF08693.10 OAG18105.1 - 1.3 8.5 3.2 2.2 7.8 3.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WD40 PF00400.32 OAG18106.1 - 1.2e-21 76.6 9.9 1.7e-06 28.6 0.7 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG18106.1 - 1.1e-12 48.0 0.5 0.06 13.6 0.0 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG18106.1 - 0.0037 16.6 0.0 19 4.5 0.0 3.4 2 2 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 OAG18106.1 - 0.034 14.0 0.0 0.56 10.1 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG18106.1 - 0.099 11.3 0.0 1.4 7.5 0.0 2.2 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG18106.1 - 0.11 11.5 0.1 1.1 8.1 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 OAG18106.1 - 0.13 11.8 0.0 11 5.4 0.0 2.7 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Guanylate_kin PF00625.21 OAG18107.1 - 9.9e-58 194.8 0.0 1.2e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OAG18107.1 - 8.9e-05 22.9 0.1 0.00028 21.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG18107.1 - 0.0007 20.2 0.3 0.0035 17.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG18107.1 - 0.00084 19.9 0.1 0.00098 19.7 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OAG18107.1 - 0.00086 19.6 0.0 0.0025 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG18107.1 - 0.001 19.3 0.2 0.012 15.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAG18107.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 OAG18107.1 - 0.0022 18.4 0.0 0.0045 17.4 0.0 1.6 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 OAG18107.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 OAG18107.1 - 0.0078 15.9 1.0 1.9 8.1 0.0 2.5 1 1 2 3 3 3 1 Thymidylate kinase MMR_HSR1 PF01926.23 OAG18107.1 - 0.0095 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG18107.1 - 0.01 16.1 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG18107.1 - 0.011 15.0 0.0 0.45 9.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 OAG18107.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 OAG18107.1 - 0.013 15.4 0.1 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_23 PF13476.6 OAG18107.1 - 0.015 15.8 1.0 0.032 14.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG18107.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAG18107.1 - 0.038 14.0 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG18107.1 - 0.041 13.6 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG18107.1 - 0.054 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 OAG18107.1 - 0.066 12.9 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 OAG18107.1 - 0.068 13.6 0.2 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG18107.1 - 0.069 12.7 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OAG18107.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAG18107.1 - 0.084 12.8 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 OAG18107.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 OAG18107.1 - 0.19 11.2 0.1 0.45 9.9 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein WD40 PF00400.32 OAG18108.1 - 1.8e-20 72.8 6.7 6.4e-05 23.6 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG18108.1 - 4.4e-12 46.1 0.0 5.1e-08 33.1 0.0 4.3 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG18108.1 - 0.0022 17.9 0.6 0.66 9.8 0.1 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAG18108.1 - 0.04 13.9 0.2 11 6.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OAG18108.1 - 0.066 11.8 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cadherin_4 PF17803.1 OAG18108.1 - 0.076 13.6 1.5 0.52 11.0 0.0 2.8 2 1 0 2 2 2 0 Bacterial cadherin-like domain D123 PF07065.14 OAG18109.1 - 1.3e-06 27.8 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 D123 Cupin_8 PF13621.6 OAG18109.1 - 0.066 12.9 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Response_reg PF00072.24 OAG18110.1 - 1.5e-20 73.4 0.0 3.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG18110.1 - 2e-20 73.4 0.1 5.6e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG18110.1 - 4.6e-12 45.8 0.0 1.5e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAG18110.1 - 4.7e-06 27.3 0.0 1e-05 26.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OAG18110.1 - 0.00082 19.7 0.1 0.034 14.5 0.0 3.1 2 1 0 2 2 2 1 GAF domain AAA PF00004.29 OAG18111.1 - 1e-16 61.5 0.0 2.1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG18111.1 - 0.0018 18.7 0.0 0.0047 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG18111.1 - 0.0036 17.3 0.1 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG18111.1 - 0.013 15.8 0.1 0.041 14.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG18111.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG18111.1 - 0.032 14.6 0.1 0.086 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG18111.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zot PF05707.12 OAG18111.1 - 0.098 12.3 0.2 3.3 7.3 0.0 2.5 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.22 OAG18111.1 - 0.14 12.6 0.2 4 7.9 0.0 2.8 3 0 0 3 3 3 0 RNA helicase ATPase PF06745.13 OAG18111.1 - 0.2 11.0 0.9 0.28 10.5 0.2 1.5 2 0 0 2 2 2 0 KaiC zf-C2H2 PF00096.26 OAG18112.1 - 1.5e-05 25.1 12.0 0.0053 17.1 0.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG18112.1 - 0.0077 17.0 8.8 2.7 9.1 1.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger DUF1936 PF09151.10 OAG18112.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) CDPS PF16715.5 OAG18113.1 - 0.021 14.5 0.7 1.1 8.9 0.6 2.4 2 0 0 2 2 2 0 Cyclodipeptide synthase Pex19 PF04614.12 OAG18115.1 - 7.1e-74 248.7 23.0 1.3e-73 247.7 23.0 1.4 1 0 0 1 1 1 1 Pex19 protein family ABC_tran_Xtn PF12848.7 OAG18115.1 - 0.02 14.9 0.9 0.02 14.9 0.9 2.9 3 0 0 3 3 3 0 ABC transporter NB-LRR PF12061.8 OAG18115.1 - 0.061 12.7 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Late blight resistance protein R1 GCP_C_terminal PF04130.13 OAG18115.1 - 5.8 6.3 6.8 5.2 6.4 3.8 2.2 2 1 0 2 2 2 0 Gamma tubulin complex component C-terminal UQ_con PF00179.26 OAG18116.1 - 4.3e-48 162.5 0.0 4.8e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG18116.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG18116.1 - 0.011 15.9 1.0 0.031 14.5 1.0 1.7 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.22 OAG18117.1 - 2.6e-15 56.0 0.0 4.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAD PF05557.13 OAG18117.1 - 0.18 10.2 10.4 0.22 9.9 10.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 OAG18117.1 - 0.24 11.4 12.7 0.35 10.9 12.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CCDC71L PF15374.6 OAG18117.1 - 0.25 10.5 1.4 0.33 10.2 1.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Band_3_cyto PF07565.13 OAG18117.1 - 0.29 10.9 2.4 0.36 10.6 2.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ACCA PF03255.14 OAG18117.1 - 3.5 7.5 7.5 5.8 6.8 7.5 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF724 PF05266.14 OAG18117.1 - 4.2 7.2 9.7 6 6.7 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.24 OAG18117.1 - 5.2 7.0 6.1 7.4 6.5 6.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BTB PF00651.31 OAG18118.1 - 0.00043 20.5 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_14 PF08484.11 OAG18118.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain PPR_2 PF13041.6 OAG18122.1 - 6.4e-17 61.5 0.3 2e-05 24.7 0.0 4.4 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.20 OAG18122.1 - 3.6e-13 48.8 0.1 0.00043 20.3 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 OAG18122.1 - 4.2e-10 39.6 0.0 0.043 13.9 0.0 4.1 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OAG18122.1 - 9.2e-05 21.9 0.1 0.00041 19.8 0.1 2.1 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG18122.1 - 0.00064 19.4 0.5 1.9 8.2 0.0 3.8 3 1 0 3 3 3 1 PPR repeat ERAP1_C PF11838.8 OAG18122.1 - 0.1 12.1 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 ERAP1-like C-terminal domain MRP-S25 PF13741.6 OAG18123.1 - 7.2e-69 231.8 1.5 4.9e-62 209.5 1.6 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAG18123.1 - 0.0013 19.0 0.1 0.0037 17.5 0.1 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Pec_lyase_C PF00544.19 OAG18124.1 - 9.7e-40 136.4 6.9 1.3e-39 135.9 6.9 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG18124.1 - 0.00024 21.0 7.6 0.028 14.3 7.7 2.5 1 1 0 1 1 1 1 Right handed beta helix region Sugar_tr PF00083.24 OAG18125.1 - 1.9e-46 158.9 15.8 2.4e-46 158.5 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG18125.1 - 5.2e-18 65.1 21.6 5.2e-18 65.1 21.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC_membrane PF00664.23 OAG18126.1 - 1.9e-88 296.7 33.2 4.1e-49 167.7 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG18126.1 - 3.3e-69 231.7 0.0 6.6e-36 123.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG18126.1 - 1.2e-11 44.5 3.7 0.0022 17.5 0.1 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG18126.1 - 3.7e-10 40.5 0.7 0.00074 19.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 OAG18126.1 - 2.9e-08 33.0 0.6 0.0066 15.3 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 OAG18126.1 - 3.3e-08 33.9 0.4 0.019 15.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG18126.1 - 2.9e-07 30.5 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAG18126.1 - 3.7e-06 27.0 0.0 2.1 8.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAG18126.1 - 4.6e-06 26.4 0.0 0.054 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG18126.1 - 1.4e-05 24.7 7.4 0.026 14.2 0.3 3.8 4 0 0 4 4 4 2 P-loop containing region of AAA domain Rad17 PF03215.15 OAG18126.1 - 4.1e-05 23.6 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 OAG18126.1 - 5.2e-05 23.1 0.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OAG18126.1 - 6.3e-05 23.0 0.3 0.37 10.8 0.0 3.4 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 OAG18126.1 - 0.00011 22.4 0.6 0.81 10.0 0.0 3.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 OAG18126.1 - 0.00011 22.4 0.0 0.41 10.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OAG18126.1 - 0.00011 22.6 2.1 6.8 7.1 1.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG18126.1 - 0.00098 18.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG18126.1 - 0.0016 18.8 0.0 3.5 8.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 OAG18126.1 - 0.0018 18.0 0.1 6 6.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 OAG18126.1 - 0.0054 17.0 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG18126.1 - 0.0097 16.5 0.0 5.5 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG18126.1 - 0.015 15.3 0.0 12 5.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 OAG18126.1 - 0.03 14.4 0.0 14 5.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 OAG18126.1 - 0.031 14.4 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain BAR_3_WASP_bdg PF10456.9 OAG18126.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein NACHT PF05729.12 OAG18126.1 - 0.17 11.8 0.3 4.7 7.1 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 OAG18126.1 - 0.49 10.9 7.6 3.4 8.1 0.2 3.3 4 0 0 4 4 3 0 AAA domain DUF2269 PF10027.9 OAG18126.1 - 2.6 8.1 8.1 0.15 12.1 0.2 3.1 3 0 0 3 3 2 0 Predicted integral membrane protein (DUF2269) Cu-oxidase_2 PF07731.14 OAG18127.1 - 3.2e-06 26.9 0.5 0.0036 17.0 0.6 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG18127.1 - 2.4e-05 24.3 1.2 0.0068 16.4 0.0 3.1 3 1 0 3 3 3 2 Multicopper oxidase NmrA PF05368.13 OAG18128.1 - 8.6e-19 68.0 0.1 1.1e-18 67.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG18128.1 - 1.6e-13 50.9 0.0 2.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG18128.1 - 7.4e-08 32.1 0.1 2.2e-07 30.6 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG18128.1 - 4.3e-05 23.5 0.3 6.9e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 KR domain LpxI_N PF17930.1 OAG18128.1 - 0.00098 19.0 0.2 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 LpxI N-terminal domain DapB_N PF01113.20 OAG18128.1 - 0.0031 17.6 2.1 0.079 13.1 2.1 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAG18128.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG18128.1 - 0.022 14.2 0.2 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase SMI1_KNR4 PF09346.10 OAG18129.1 - 0.00035 21.0 0.0 0.0034 17.8 0.0 2.4 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) T6SS_VasJ PF16989.5 OAG18129.1 - 0.016 14.7 0.0 0.25 10.8 0.0 2.3 1 1 1 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Fungal_trans PF04082.18 OAG18130.1 - 6.3e-10 38.5 1.0 1.1e-09 37.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18130.1 - 0.0014 18.7 12.4 0.0029 17.7 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 OAG18131.1 - 0.14 12.4 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper MFS_1 PF07690.16 OAG18132.1 - 7e-28 97.6 32.6 6.4e-21 74.7 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18132.1 - 3.5e-18 65.7 21.8 4.5e-17 62.0 21.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter NAD_binding_4 PF07993.12 OAG18133.1 - 4.1e-35 121.2 0.0 5.2e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG18133.1 - 1.3e-10 41.1 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG18133.1 - 0.00011 21.3 0.0 0.00035 19.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG18133.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ECH_1 PF00378.20 OAG18134.1 - 5.1e-23 81.7 0.0 6.2e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG18134.1 - 8.9e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CDH-cyt PF16010.5 OAG18135.1 - 1.3e-50 171.6 3.3 1.7e-50 171.3 2.0 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase SBBP PF06739.11 OAG18135.1 - 0.0092 16.0 2.0 1 9.4 0.0 3.6 4 0 0 4 4 4 2 Beta-propeller repeat GSDH PF07995.11 OAG18135.1 - 0.02 14.2 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase FMO-like PF00743.19 OAG18136.1 - 3.1e-11 42.4 0.0 9.8e-11 40.8 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG18136.1 - 1.4e-08 34.8 0.3 5.3e-08 33.0 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG18136.1 - 6.9e-08 32.1 0.0 2e-07 30.6 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG18136.1 - 9.5e-07 28.3 0.0 9.6e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG18136.1 - 2.3e-05 23.7 0.0 0.00084 18.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG18136.1 - 3.6e-05 23.5 0.1 0.0057 16.3 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG18136.1 - 0.00014 21.2 0.0 0.00038 19.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAG18136.1 - 0.0029 16.8 0.0 0.0078 15.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG18136.1 - 0.052 13.5 0.1 12 5.9 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pkinase PF00069.25 OAG18138.1 - 6.8e-73 245.3 0.0 1.6e-72 244.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18138.1 - 2.2e-51 174.7 0.0 4.6e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG18138.1 - 0.00059 18.7 0.9 0.0011 17.8 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase V-ATPase_H_N PF03224.14 OAG18138.1 - 0.0079 15.5 1.8 16 4.6 0.0 3.1 3 0 0 3 3 3 2 V-ATPase subunit H Med15_fungi PF05397.12 OAG18138.1 - 0.01 16.1 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 Kinase-like PF14531.6 OAG18138.1 - 0.066 12.5 0.0 0.4 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Arm PF00514.23 OAG18138.1 - 0.1 12.7 0.1 15 5.8 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat adh_short_C2 PF13561.6 OAG18139.1 - 2.1e-38 132.2 0.4 3e-38 131.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18139.1 - 3.6e-37 127.7 0.2 5.2e-37 127.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG18139.1 - 3.1e-12 46.8 2.6 1.1e-10 41.8 2.5 2.2 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OAG18139.1 - 0.001 19.1 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAG18139.1 - 0.0026 17.2 0.0 0.0059 16.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 OAG18139.1 - 0.004 17.7 0.1 0.012 16.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 OAG18139.1 - 0.018 14.4 0.0 0.047 13.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 OAG18139.1 - 0.018 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAG18139.1 - 0.024 13.9 0.2 0.045 13.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 OAG18139.1 - 0.035 14.5 0.0 0.57 10.6 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF1776 PF08643.10 OAG18139.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_oxidored PF12831.7 OAG18139.1 - 0.39 10.0 2.9 0.68 9.2 2.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase BCS1_N PF08740.11 OAG18140.1 - 3e-19 69.7 0.0 4.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG18140.1 - 5.5e-16 59.2 0.0 1.2e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAG18140.1 - 0.00047 20.2 0.0 0.014 15.4 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG18140.1 - 0.0037 17.4 0.0 0.0092 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG18140.1 - 0.0044 17.4 0.0 0.058 13.8 0.0 2.6 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 OAG18140.1 - 0.031 14.7 0.2 0.099 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 OAG18140.1 - 0.061 13.1 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG18140.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3775 PF12616.8 OAG18140.1 - 0.084 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) AAA_5 PF07728.14 OAG18140.1 - 0.092 12.7 0.0 0.69 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 OAG18140.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.6 OAG18140.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Polyoma_lg_T_C PF06431.11 OAG18140.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DnaJ PF00226.31 OAG18141.1 - 2.7e-13 49.8 1.3 3.8e-13 49.3 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain p450 PF00067.22 OAG18143.1 - 5.7e-56 190.2 0.0 1.4e-55 188.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M60_C PF18630.1 OAG18144.1 - 0.0095 16.0 0.4 0.25 11.5 0.0 2.6 2 0 0 2 2 2 1 Peptidase M60 C-terminal domain BTB PF00651.31 OAG18144.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 OAG18145.1 - 0.00084 19.6 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Aa_trans PF01490.18 OAG18146.1 - 2.5e-77 260.3 25.8 3.9e-77 259.7 25.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CytochromB561_N PF09786.9 OAG18147.1 - 0.079 12.0 2.9 0.075 12.0 2.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pap_E4 PF02711.14 OAG18147.1 - 0.27 12.2 5.2 0.42 11.6 5.2 1.4 1 0 0 1 1 1 0 E4 protein RCDG1 PF15725.5 OAG18147.1 - 1.5 9.2 7.4 2.6 8.5 7.4 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF5345 PF17280.2 OAG18154.1 - 0.17 11.8 2.2 0.29 11.1 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) NmrA PF05368.13 OAG18155.1 - 7.6e-17 61.6 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG18155.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG18155.1 - 0.023 14.2 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG18155.1 - 0.098 12.6 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 KR domain Cellulase PF00150.18 OAG18156.1 - 1.1e-20 74.3 0.6 1.3e-20 74.0 0.6 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) sCache_3_3 PF17202.4 OAG18156.1 - 0.12 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Single cache domain 3 DUF2285 PF10074.9 OAG18156.1 - 0.18 12.4 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) zf-RING_5 PF14634.6 OAG18157.1 - 0.00011 22.1 6.1 0.00021 21.2 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UPF0242 PF06785.11 OAG18157.1 - 0.11 12.7 3.4 0.16 12.1 3.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus P33MONOX PF15302.6 OAG18158.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase p450 PF00067.22 OAG18159.1 - 3.9e-62 210.5 0.0 5.5e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 OAG18161.1 - 1.5e-10 40.8 0.1 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_1_2 PF13586.6 OAG18161.1 - 0.14 12.6 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain p450 PF00067.22 OAG18162.1 - 4.7e-66 223.4 0.0 5.9e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG18164.1 - 4.9e-14 52.0 0.1 8.2e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUR7 PF06687.12 OAG18165.1 - 2.6e-08 33.8 8.1 3.5e-08 33.3 8.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family FA_desaturase PF00487.24 OAG18166.1 - 3.9e-25 89.1 15.7 5.6e-25 88.6 15.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 OAG18166.1 - 1.7e-17 62.6 0.9 3.1e-17 61.8 0.9 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DnaJ PF00226.31 OAG18167.1 - 2.2e-16 59.7 1.0 3.7e-16 59.0 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OAG18167.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein PRK PF00485.18 OAG18168.1 - 2.8e-07 30.5 0.0 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OAG18168.1 - 6.7e-05 23.1 0.0 0.00017 21.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG18168.1 - 0.00099 18.4 0.1 0.0064 15.8 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 OAG18168.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG18168.1 - 0.0015 19.0 0.2 0.011 16.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OAG18168.1 - 0.0085 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MeaB PF03308.16 OAG18168.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 OAG18168.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 OAG18168.1 - 0.035 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF463 PF04317.12 OAG18168.1 - 0.045 12.7 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 NB-ARC PF00931.22 OAG18168.1 - 0.057 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SinI PF08671.10 OAG18168.1 - 0.058 13.2 0.3 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Anti-repressor SinI AAA_14 PF13173.6 OAG18168.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAG18168.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 OAG18168.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TarS_C1 PF18674.1 OAG18168.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 ABC_tran PF00005.27 OAG18168.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DAO PF01266.24 OAG18169.1 - 4.2e-33 115.4 0.5 5.5e-33 115.0 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG18169.1 - 0.00042 19.6 0.0 0.84 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG18169.1 - 0.026 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG18169.1 - 0.34 10.9 1.3 2.9 7.9 0.1 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding PRELI PF04707.14 OAG18170.1 - 5.9e-45 152.9 0.1 7.3e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 PRELI-like family Thioredox_DsbH PF03190.15 OAG18170.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF255 UPF0160 PF03690.13 OAG18171.1 - 7.1e-126 420.1 0.0 8e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 OAG18172.1 - 6.3e-156 519.6 6.1 7.2e-156 519.4 6.1 1.0 1 0 0 1 1 1 1 ICE2 DUF5108 PF17133.4 OAG18172.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5108) Hexapep PF00132.24 OAG18173.1 - 2.3e-12 46.1 16.3 4.3e-09 35.7 4.4 3.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG18173.1 - 2.1e-09 36.9 12.3 1.3e-06 28.1 2.6 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 OAG18173.1 - 3.3e-08 33.5 8.7 3.3e-08 33.5 8.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 OAG18173.1 - 0.00028 21.1 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Ribosomal_L3 PF00297.22 OAG18174.1 - 3.7e-16 59.1 4.9 9.1e-13 47.9 4.9 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 Pec_lyase_C PF00544.19 OAG18176.1 - 1.1e-11 44.7 10.3 3.1e-10 40.0 10.3 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG18176.1 - 5.3e-05 23.1 12.9 0.00011 22.0 12.1 1.9 1 1 0 1 1 1 1 Right handed beta helix region Phage_attach PF05354.11 OAG18176.1 - 0.0045 16.8 0.1 0.016 15.1 0.1 1.9 1 0 0 1 1 1 1 Phage Head-Tail Attachment SnoaL_4 PF13577.6 OAG18178.1 - 5e-55 185.0 1.4 7.6e-22 77.8 0.9 3.2 3 0 0 3 3 3 3 SnoaL-like domain DUF4199 PF13858.6 OAG18179.1 - 2.5 8.5 6.1 2.4 8.6 1.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4199) Amidase PF01425.21 OAG18181.1 - 1.6e-60 205.4 0.0 2.2e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Amidase Cwf_Cwc_15 PF04889.12 OAG18183.1 - 0.00035 20.4 1.6 0.00043 20.1 1.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pep1_7 PF17232.2 OAG18183.1 - 0.047 14.1 2.2 0.059 13.8 0.6 1.9 1 1 0 1 1 1 0 Elicitor peptide 1-7 Cut8 PF08559.10 OAG18185.1 - 1.3e-82 277.1 0.0 1.5e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DBD_HTH PF18430.1 OAG18185.1 - 0.099 12.4 1.1 0.21 11.4 1.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Rhamno_transf PF11316.8 OAG18185.1 - 0.19 11.1 0.0 4.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Putative rhamnosyl transferase rRNA_proc-arch PF13234.6 OAG18186.1 - 1.4e-90 303.9 0.1 1.4e-90 303.9 0.1 2.1 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 OAG18186.1 - 4.1e-56 189.1 3.3 1.2e-55 187.7 2.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OAG18186.1 - 1.1e-18 67.6 0.1 4.2e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG18186.1 - 6.5e-07 29.7 0.0 3.4e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG18186.1 - 5.8e-06 26.4 0.0 1.8e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OAG18186.1 - 0.017 14.2 0.0 0.045 12.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 OAG18186.1 - 0.028 14.3 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAG18186.1 - 0.06 13.6 0.1 0.49 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF5388 PF17363.2 OAG18186.1 - 0.14 12.3 0.3 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5388) BRICHOS PF04089.14 OAG18186.1 - 4.2 7.7 5.3 21 5.4 0.1 3.1 3 0 0 3 3 3 0 BRICHOS domain APG6_N PF17675.1 OAG18186.1 - 6.5 7.3 9.4 3.3 8.3 0.2 3.8 3 0 0 3 3 3 0 Apg6 coiled-coil region KELK PF15796.5 OAG18186.1 - 7.7 7.1 7.9 1.2 9.7 0.2 3.5 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COX7C PF02935.16 OAG18187.1 - 1.3e-24 86.2 2.4 1.6e-24 85.9 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.12 OAG18188.1 - 0 1014.5 0.0 0 1014.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 OAG18188.1 - 0.00048 20.4 0.2 3 8.2 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_Nu1 PF07471.12 OAG18188.1 - 0.0048 16.7 1.6 0.0048 16.7 1.6 1.9 2 0 0 2 2 2 1 Phage DNA packaging protein Nu1 ApoLp-III PF07464.11 OAG18188.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.2 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) HU-CCDC81_euk_2 PF18289.1 OAG18188.1 - 0.13 12.4 0.5 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 CCDC81 eukaryotic HU domain 2 DUF1192 PF06698.11 OAG18188.1 - 0.3 11.2 2.7 0.99 9.5 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Swm2 PF17083.5 OAG18188.1 - 0.93 9.5 3.7 0.66 10.0 0.3 2.4 3 0 0 3 3 3 0 Nucleolar protein Swm2 FlgN PF05130.12 OAG18188.1 - 1.4 9.4 9.2 0.57 10.7 0.5 3.2 3 0 0 3 3 3 0 FlgN protein Polysacc_deac_1 PF01522.21 OAG18190.1 - 1.2e-25 89.7 0.0 1.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAG18190.1 - 0.0013 18.0 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Fungal_trans_2 PF11951.8 OAG18191.1 - 1e-08 34.4 0.0 1.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18191.1 - 0.065 13.4 2.9 0.14 12.3 2.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.24 OAG18192.1 - 1.2e-37 129.2 41.1 1.1e-20 74.1 19.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Trypan_PARP PF05887.11 OAG18192.1 - 0.015 15.3 1.0 0.05 13.6 1.0 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF733 PF05306.11 OAG18192.1 - 0.11 12.8 1.7 0.18 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Pex14_N PF04695.13 OAG18192.1 - 2.4 8.8 0.0 2.4 8.8 0.0 3.9 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_4 PF13637.6 OAG18193.1 - 6e-14 52.2 0.5 3.2e-05 24.4 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG18193.1 - 8.5e-13 48.7 0.0 3e-05 24.5 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG18193.1 - 1.8e-05 24.9 0.6 1.3 9.4 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG18193.1 - 2.2e-05 24.5 2.6 0.085 13.5 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OAG18193.1 - 0.008 16.6 3.8 0.72 10.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat DUF1949 PF09186.11 OAG18193.1 - 0.024 14.5 0.3 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) p450 PF00067.22 OAG18194.1 - 4.3e-56 190.6 0.0 5.5e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YwiC PF14256.6 OAG18195.1 - 0.0033 17.7 2.9 0.0033 17.7 2.9 2.7 2 1 0 3 3 3 1 YwiC-like protein LysM PF01476.20 OAG18196.1 - 2e-08 34.1 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain Actino_peptide PF14408.6 OAG18196.1 - 0.04 14.0 0.2 0.09 12.9 0.1 1.6 1 1 1 2 2 2 0 Ribosomally synthesised peptide in actinomycetes DUF903 PF06004.12 OAG18196.1 - 0.057 13.3 0.4 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DUF4238 PF14022.6 OAG18197.1 - 2e-13 50.5 0.1 3.3e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Peptidase_M41 PF01434.18 OAG18198.1 - 5.9e-68 228.5 0.0 1.1e-67 227.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAG18198.1 - 8.8e-42 142.7 0.2 3.3e-41 140.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG18198.1 - 1.1e-11 44.4 0.2 3.3e-11 42.8 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAG18198.1 - 1.1e-11 45.1 0.0 2.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 OAG18198.1 - 0.0054 16.7 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG18198.1 - 0.011 16.1 0.3 1.3 9.3 0.3 2.9 1 1 1 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 OAG18198.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 OAG18198.1 - 0.037 14.3 0.2 7.3 6.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 OAG18198.1 - 0.043 13.9 0.2 0.51 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG18198.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 OAG18198.1 - 0.11 13.0 0.7 0.92 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain UcrQ PF02939.16 OAG18200.1 - 3.5e-28 97.4 0.3 4.1e-28 97.1 0.3 1.1 1 0 0 1 1 1 1 UcrQ family Fungal_trans_2 PF11951.8 OAG18201.1 - 5.8e-12 45.1 6.8 8.8e-12 44.5 6.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.13 OAG18202.1 - 4.6e-15 55.0 0.0 1.2e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG18202.1 - 7.1e-07 28.4 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG18202.1 - 0.0026 17.1 0.1 0.039 13.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAG18202.1 - 0.0054 16.5 1.7 1.5 8.6 0.1 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Lipase_3 PF01764.25 OAG18202.1 - 0.0085 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.11 OAG18202.1 - 0.0091 15.0 1.1 0.061 12.3 1.1 2.0 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.14 OAG18202.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG18202.1 - 0.038 14.6 0.2 0.063 13.9 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 OAG18203.1 - 4.6e-13 49.2 0.2 8.1e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG18203.1 - 3.2e-08 33.7 0.7 6.6e-08 32.7 0.7 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG18203.1 - 2e-07 30.3 0.0 0.015 14.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG18203.1 - 1.3e-05 25.7 0.2 3.5e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 OAG18203.1 - 1.3e-05 24.9 0.2 1.9e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAG18203.1 - 0.00034 19.9 0.0 0.0073 15.5 0.0 2.6 2 1 1 3 3 3 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 OAG18203.1 - 0.00069 19.9 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 OAG18203.1 - 0.017 15.8 0.0 0.031 15.0 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 OAG18203.1 - 0.025 14.7 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAG18203.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG18203.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 OAG18203.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Neurensin PF14927.6 OAG18204.1 - 0.045 13.5 0.1 0.096 12.4 0.1 1.5 1 1 0 1 1 1 0 Neurensin DUF4567 PF15131.6 OAG18204.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) Bac_export_3 PF01313.19 OAG18204.1 - 0.12 12.3 0.5 0.12 12.3 0.5 1.7 2 0 0 2 2 2 0 Bacterial export proteins, family 3 PRT_C PF08372.10 OAG18205.1 - 0.082 12.7 1.6 0.085 12.6 1.6 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Gin PF10764.9 OAG18206.1 - 0.048 13.6 0.2 0.067 13.2 0.2 1.2 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-met2 PF12907.7 OAG18206.1 - 0.083 13.0 0.6 0.14 12.3 0.6 1.4 1 0 0 1 1 1 0 Zinc-binding HET PF06985.11 OAG18207.1 - 6.5e-34 117.4 0.8 1e-33 116.7 0.8 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGEF PF00617.19 OAG18207.1 - 0.15 12.2 0.1 0.6 10.3 0.1 1.9 1 1 0 1 1 1 0 RasGEF domain 4F5 PF04419.14 OAG18208.1 - 3.7e-13 50.1 9.9 3.7e-13 50.1 9.9 2.2 2 0 0 2 2 2 1 4F5 protein family Cu_bind_like PF02298.17 OAG18209.1 - 0.11 12.6 0.2 0.21 11.6 0.2 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain SMN PF06003.12 OAG18211.1 - 0.00015 21.1 12.0 0.001 18.4 3.4 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Pex14_N PF04695.13 OAG18211.1 - 0.032 14.9 1.7 0.042 14.5 1.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nitrate_red_del PF02613.15 OAG18211.1 - 0.04 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Nitrate reductase delta subunit RRM_1 PF00076.22 OAG18212.1 - 4.2e-15 55.3 0.1 9.4e-15 54.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG18212.1 - 0.0098 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAG18212.1 - 0.036 14.0 0.5 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 RL domain CSRNP_N PF16019.5 OAG18212.1 - 0.29 11.0 1.6 1.1 9.1 1.6 2.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Cupin_2 PF07883.11 OAG18213.1 - 3.9e-06 26.5 0.1 8.1e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAG18213.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin CDO_I PF05995.12 OAG18213.1 - 0.1 11.9 0.2 0.34 10.2 0.1 1.7 1 1 1 2 2 2 0 Cysteine dioxygenase type I Sec23_trunk PF04811.15 OAG18214.1 - 2.5e-75 253.2 0.0 4.1e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAG18214.1 - 3.7e-30 104.5 0.1 7.8e-30 103.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAG18214.1 - 3.9e-26 90.9 0.2 4.8e-25 87.4 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAG18214.1 - 4.2e-15 55.5 8.0 8.1e-15 54.6 8.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG18214.1 - 2.6e-14 52.9 0.0 2.5e-12 46.5 0.0 2.6 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG18214.1 - 0.061 12.7 0.3 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glyco_hydro_61 PF03443.14 OAG18215.1 - 7.6e-46 156.6 0.1 1.3e-45 155.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.18 OAG18218.1 - 2.6e-08 33.8 10.1 2.6e-08 33.8 10.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG18218.1 - 4.6e-06 25.9 0.0 6.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG18219.1 - 1.3e-21 76.9 0.1 2.5e-19 69.5 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18219.1 - 3.5e-11 43.1 0.1 2.1e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18219.1 - 6.3e-09 36.0 0.1 8.9e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG18219.1 - 0.016 14.6 0.0 0.042 13.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG18219.1 - 0.048 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG18219.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2 PF00096.26 OAG18221.1 - 5.3e-10 39.2 11.2 0.0073 16.7 0.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG18221.1 - 8.9e-08 32.3 7.9 0.077 13.9 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG18221.1 - 0.029 14.4 3.7 4.3 7.5 2.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAG18221.1 - 0.1 12.9 5.3 0.3 11.4 0.9 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 OAG18221.1 - 0.15 12.1 0.6 0.4 10.8 0.6 1.7 1 0 0 1 1 1 0 BED zinc finger Exonuc_VII_L PF02601.15 OAG18221.1 - 0.37 10.3 6.9 0.051 13.1 1.7 2.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit zf-H2C2_2 PF13465.6 OAG18221.1 - 0.82 10.2 5.4 15 6.2 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 OAG18221.1 - 1.6 9.4 5.9 0.97 10.1 0.1 3.1 3 1 1 4 4 4 0 FOXP coiled-coil domain EamA PF00892.20 OAG18222.1 - 5.6 7.1 14.3 3.5 7.8 1.0 3.0 3 0 0 3 3 3 0 EamA-like transporter family EMP24_GP25L PF01105.24 OAG18223.1 - 2.1e-50 171.2 0.1 2.4e-50 171.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TRAF_BIRC3_bd PF16673.5 OAG18223.1 - 0.024 14.4 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain HeLo PF14479.6 OAG18223.1 - 0.03 14.2 0.2 0.05 13.4 0.2 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF1940 PF09155.10 OAG18223.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) adh_short PF00106.25 OAG18224.1 - 1.8e-31 109.1 0.0 2.8e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18224.1 - 3.4e-22 79.1 0.0 4.5e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18224.1 - 0.00033 20.6 0.1 0.011 15.6 0.1 2.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG18224.1 - 0.0014 18.3 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF5375 PF17345.2 OAG18224.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5375) SANT_DAMP1_like PF16282.5 OAG18225.1 - 5.6e-29 100.2 1.0 1.2e-28 99.2 1.0 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 BUD22 PF09073.10 OAG18225.1 - 0.0022 17.4 21.2 0.0045 16.4 21.2 1.7 1 0 0 1 1 1 1 BUD22 DMAP1 PF05499.12 OAG18225.1 - 0.017 15.0 4.6 0.052 13.4 1.3 2.3 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Pkinase PF00069.25 OAG18226.1 - 1.5e-27 96.6 0.0 2.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18226.1 - 1.1e-14 54.3 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG18226.1 - 5.5e-07 28.7 0.0 1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Nucleoporin_C PF03177.14 OAG18227.1 - 5.1e-147 491.2 5.7 6.3e-147 490.9 5.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAG18227.1 - 1.7e-40 139.1 0.0 2.2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like PapC_C PF13953.6 OAG18227.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 PapC C-terminal domain HABP4_PAI-RBP1 PF04774.15 OAG18228.1 - 0.0036 18.1 7.0 0.0077 17.1 7.0 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 OAG18229.1 - 1e-42 144.7 3.7 1.7e-42 144.0 3.7 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAG18229.1 - 2.2e-38 131.5 0.0 3.1e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Acetyltransf_1 PF00583.25 OAG18230.1 - 1.2e-13 51.3 0.1 1.5e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG18230.1 - 2.9e-08 34.0 0.2 4.2e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG18230.1 - 4.3e-08 33.2 0.0 4.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG18230.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 OAG18230.1 - 9.6e-05 22.1 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 OAG18230.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAG18230.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 OAG18231.1 - 8.5e-16 58.2 0.0 1.8e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG18231.1 - 2e-15 57.1 0.0 3e-12 46.9 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG18231.1 - 5.7e-12 46.2 2.8 1.4e-11 45.0 2.8 1.7 1 0 0 1 1 1 1 RecQ zinc-binding UBA PF00627.31 OAG18232.1 - 2.7e-07 30.3 0.1 1.1e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.20 OAG18232.1 - 1.8e-06 28.1 0.0 6e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 UBX domain zf-C2H2_2 PF12756.7 OAG18232.1 - 0.091 13.1 1.8 0.11 12.9 0.3 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L11_N PF03946.14 OAG18232.1 - 0.13 12.2 1.1 1.7 8.6 0.0 2.7 2 1 0 2 2 2 0 Ribosomal protein L11, N-terminal domain CDC45 PF02724.14 OAG18232.1 - 0.74 8.0 15.3 0.84 7.8 15.3 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_jaz PF12171.8 OAG18232.1 - 4.2 7.8 4.8 1.6 9.1 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Motile_Sperm PF00635.26 OAG18233.1 - 2.3e-26 91.8 0.0 4.1e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 OAG18233.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Asn_synthase PF00733.21 OAG18234.1 - 3.3e-92 309.9 0.0 2.6e-53 182.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAG18234.1 - 9.9e-36 122.4 0.0 2.2e-35 121.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAG18234.1 - 3.8e-27 95.1 0.0 7e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG18234.1 - 4.8e-06 26.2 0.0 8.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 OAG18234.1 - 0.0026 16.9 0.0 0.0045 16.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase PQ-loop PF04193.14 OAG18235.1 - 2.4e-38 129.7 4.6 1.2e-18 66.6 0.0 3.1 2 1 1 3 3 3 2 PQ loop repeat FeoB_associated PF12669.7 OAG18235.1 - 0.0047 17.3 3.2 13 6.3 0.0 4.1 4 0 0 4 4 4 2 FeoB-associated Cys-rich membrane protein TMEM132D_C PF15706.5 OAG18235.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mid2 PF04478.12 OAG18236.1 - 0.87 9.4 10.1 0.029 14.2 2.0 2.5 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.10 OAG18236.1 - 7.7 5.1 6.7 9.8 4.7 6.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ydc2-catalyt PF09159.10 OAG18238.1 - 2.9e-71 240.5 0.1 3.7e-71 240.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 OAG18238.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 OAG18238.1 - 0.0047 17.0 0.5 4.2 7.5 0.0 3.5 2 2 1 3 3 3 2 Poxvirus A22 protein Aconitase PF00330.20 OAG18240.1 - 2.8e-143 478.2 0.0 3.5e-143 477.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG18240.1 - 7.1e-40 136.4 0.0 1.2e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain KH_1 PF00013.29 OAG18241.1 - 4.3e-09 36.1 0.0 1.8e-07 30.8 0.1 2.3 2 0 0 2 2 2 2 KH domain HPIP PF15226.6 OAG18242.1 - 0.12 12.8 3.3 0.2 12.1 3.3 1.4 1 1 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family ALS_ss_C PF10369.9 OAG18243.1 - 1.7e-14 53.8 0.0 2.5e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAG18243.1 - 4.7e-13 48.7 0.1 8.6e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OAG18243.1 - 2.5e-08 33.6 0.0 4.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain DUF2156 PF09924.9 OAG18244.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) VTC PF09359.10 OAG18245.1 - 1.4e-10 41.1 0.1 2.6e-09 36.9 0.1 2.2 1 1 0 1 1 1 1 VTC domain SPX PF03105.19 OAG18245.1 - 1.3e-07 31.9 24.3 0.00028 20.9 0.0 4.7 2 2 2 4 4 4 3 SPX domain DAO PF01266.24 OAG18247.1 - 1.3e-50 173.0 0.1 3.7e-50 171.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAG18247.1 - 1.8e-43 147.4 0.1 3.5e-43 146.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OAG18247.1 - 4.3e-07 29.4 0.2 1.1e-06 28.0 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG18247.1 - 0.00037 19.9 0.6 0.001 18.5 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG18247.1 - 0.0012 18.2 0.7 0.0043 16.3 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG18247.1 - 0.019 15.2 0.3 0.065 13.5 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OAG18247.1 - 0.031 14.2 0.2 0.074 12.9 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG18247.1 - 0.079 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAG18247.1 - 0.081 12.0 0.1 0.48 9.4 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG18247.1 - 0.087 12.1 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG18247.1 - 0.19 12.3 0.2 0.52 10.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peroxidase_2 PF01328.17 OAG18250.1 - 4.3e-51 174.1 0.0 6.1e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DPBB_1 PF03330.18 OAG18251.1 - 0.00091 19.5 0.0 0.0075 16.5 0.0 2.6 2 1 0 2 2 2 1 Lytic transglycolase Hva1_TUDOR PF11160.8 OAG18252.1 - 1.3e-11 44.5 6.6 3e-10 40.1 2.9 2.9 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Baseplate_J PF04865.14 OAG18252.1 - 0.019 14.1 1.0 0.11 11.6 1.0 1.9 1 1 0 1 1 1 0 Baseplate J-like protein S36_mt PF10937.8 OAG18253.1 - 4.5e-39 134.6 0.2 5.2e-39 134.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 OAG18254.1 - 1.7e-48 165.7 0.0 1.9e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 OAG18255.1 - 2.6e-55 186.5 0.0 5.8e-55 185.4 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAG18255.1 - 8.3e-21 74.7 0.0 2.8e-09 37.3 0.0 3.0 2 1 1 3 3 3 2 AAA domain Tcp11 PF05794.13 OAG18257.1 - 8.2e-108 361.3 0.0 8.2e-108 361.3 0.0 2.6 3 0 0 3 3 3 1 T-complex protein 11 IQ PF00612.27 OAG18257.1 - 0.054 13.3 0.1 0.25 11.2 0.1 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPF0242 PF06785.11 OAG18257.1 - 0.53 10.4 5.6 1.4 9.0 5.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DSPc PF00782.20 OAG18258.1 - 3.5e-28 98.1 0.0 4.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG18258.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OAG18258.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Trm112p PF03966.16 OAG18258.1 - 0.079 13.5 0.8 4.3 8.0 0.1 2.7 3 0 0 3 3 3 0 Trm112p-like protein zinc_ribbon_4 PF13717.6 OAG18258.1 - 0.11 12.5 2.8 6.5 6.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 OAG18259.1 - 3.6e-05 24.0 16.4 0.034 14.6 0.8 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG18259.1 - 0.012 16.4 21.4 0.4 11.6 1.2 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 OAG18259.1 - 0.24 11.4 4.2 4.7 7.2 2.8 3.2 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-BED PF02892.15 OAG18259.1 - 1.5 8.9 11.9 4.4 7.4 0.0 3.7 3 0 0 3 3 3 0 BED zinc finger zf-MYST PF17772.1 OAG18259.1 - 3.5 7.3 6.8 0.4 10.3 0.5 2.3 1 1 1 2 2 2 0 MYST family zinc finger domain Vfa1 PF08432.10 OAG18261.1 - 1.6e-59 201.3 16.8 1.8e-59 201.1 16.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 OAG18261.1 - 0.003 17.4 13.0 0.0041 17.0 13.0 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF2347 PF09804.9 OAG18261.1 - 0.057 13.0 1.2 0.071 12.7 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) GNAT_acetyltr_2 PF13718.6 OAG18261.1 - 0.073 12.5 4.5 0.092 12.1 4.5 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RNA12 PF10443.9 OAG18261.1 - 0.23 10.1 10.0 0.28 9.9 10.0 1.1 1 0 0 1 1 1 0 RNA12 protein NPR3 PF03666.13 OAG18261.1 - 0.31 9.8 9.9 0.35 9.6 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 OAG18261.1 - 0.32 11.1 4.1 0.37 10.9 4.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 OAG18261.1 - 0.34 9.8 2.8 0.37 9.7 2.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 OAG18261.1 - 0.75 8.8 9.5 0.84 8.6 9.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 OAG18261.1 - 1.3 7.2 17.7 1.5 7.0 17.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 OAG18261.1 - 2.1 7.6 16.8 2.6 7.3 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 OAG18261.1 - 3.6 6.7 6.1 4.2 6.5 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter VIR_N PF15912.5 OAG18261.1 - 4.3 6.8 10.7 5.5 6.5 10.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AAA_11 PF13086.6 OAG18261.1 - 7.7 6.2 12.7 9.7 5.9 12.7 1.2 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OAG18261.1 - 8.7 5.0 11.1 10 4.7 11.1 1.1 1 0 0 1 1 1 0 Presenilin TatD_DNase PF01026.21 OAG18262.1 - 1.7e-52 178.4 0.0 2.1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Oxidored_q6 PF01058.22 OAG18263.1 - 3.4e-22 78.7 0.0 5.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.13 OAG18264.1 - 1.2e-16 61.0 0.0 3.6e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAG18264.1 - 0.11 12.5 0.1 1.9 8.4 0.1 2.1 1 1 0 1 1 1 0 Sybindin-like family AFG1_ATPase PF03969.16 OAG18265.1 - 1.9e-59 201.4 0.3 7.3e-30 104.1 0.1 5.0 3 2 2 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 OAG18265.1 - 1.9e-05 25.1 0.1 0.0011 19.4 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG18265.1 - 2.3e-05 24.4 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG18265.1 - 0.0014 18.9 0.0 0.0042 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG18265.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAG18265.1 - 0.032 14.7 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG18265.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAG18265.1 - 0.17 11.2 0.0 0.44 9.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 OAG18265.1 - 0.21 11.3 0.0 0.53 10.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain OTCace PF00185.24 OAG18266.1 - 3.5e-45 153.9 0.0 5.2e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OAG18266.1 - 3.5e-44 150.4 0.1 5.5e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain LEA_2 PF03168.13 OAG18267.1 - 0.00023 21.6 1.5 1.3 9.6 0.0 4.6 5 0 0 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.8 OAG18267.1 - 0.00078 19.7 2.5 0.0014 18.9 0.2 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3712) HLH PF00010.26 OAG18268.1 - 7.8e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF647 PF04884.14 OAG18269.1 - 7.6e-21 74.8 0.1 1e-20 74.4 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF647 PF04884.14 OAG18270.1 - 1.1e-83 280.6 4.2 1.5e-83 280.1 4.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.19 OAG18271.1 - 4.5e-10 39.8 0.0 1.2e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF3402 PF11882.8 OAG18272.1 - 5.5 6.0 7.0 0.59 9.2 2.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3402) SOG2 PF10428.9 OAG18273.1 - 1.5e-25 90.4 15.9 5.3e-16 58.9 1.0 3.5 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 OAG18273.1 - 8.6e-18 63.9 10.4 3e-09 36.5 0.5 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAG18273.1 - 5.1e-11 42.6 12.2 1.8e-05 25.0 0.2 4.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAG18273.1 - 0.023 14.7 3.5 7.2 6.9 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat T6SS_VipA PF05591.12 OAG18273.1 - 0.064 13.0 0.4 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 LRR_1 PF00560.33 OAG18273.1 - 0.097 13.3 7.6 44 5.2 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF3135 PF11333.8 OAG18273.1 - 0.14 12.4 0.6 5.4 7.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) 60KD_IMP PF02096.20 OAG18274.1 - 3.5e-10 40.0 0.0 5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Peptidase_S37 PF05576.11 OAG18274.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 ALG11_N PF15924.5 OAG18275.1 - 2.1e-82 276.2 0.0 3e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAG18275.1 - 1.7e-22 79.8 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG18275.1 - 3.9e-10 40.3 0.0 9.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG18275.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 CENP-R PF06729.12 OAG18276.1 - 0.03 14.3 1.2 0.076 13.0 1.2 1.7 1 0 0 1 1 1 0 Kinetochore component, CENP-R Mur_ligase_M PF08245.12 OAG18277.1 - 4.6e-07 30.0 0.1 7.8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAG18277.1 - 0.0043 17.3 0.1 0.037 14.3 0.0 2.6 2 1 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF724 PF05266.14 OAG18277.1 - 0.029 14.2 1.7 0.045 13.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 OAG18277.1 - 0.22 11.3 1.3 0.53 10.1 1.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_L31e PF01198.19 OAG18278.1 - 3.6e-30 104.0 0.1 7.8e-30 103.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e zinc_ribbon_6 PF14599.6 OAG18278.1 - 5.5e-22 77.5 3.0 5.5e-22 77.5 3.0 4.2 3 2 1 5 5 3 1 Zinc-ribbon zf-CHY PF05495.12 OAG18278.1 - 9.6e-19 67.7 24.4 9.6e-19 67.7 24.4 3.6 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 OAG18278.1 - 2.2e-08 34.3 3.4 2.2e-08 34.3 3.4 4.8 3 1 2 5 5 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG18278.1 - 3.2e-05 23.7 6.0 3.2e-05 23.7 6.0 4.4 4 2 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OAG18278.1 - 0.0076 16.2 1.2 0.0076 16.2 1.2 6.2 3 2 2 5 5 5 1 Prokaryotic RING finger family 1 YL1 PF05764.13 OAG18278.1 - 0.034 14.2 5.7 0.082 13.0 5.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 OAG18278.1 - 0.083 12.3 3.6 0.14 11.5 3.6 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 OAG18278.1 - 0.19 9.8 7.2 0.29 9.2 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAG18278.1 - 1.5 7.0 4.2 2.2 6.5 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pep1_7 PF17232.2 OAG18278.1 - 6.3 7.3 6.0 46 4.6 0.1 3.0 2 0 0 2 2 2 0 Elicitor peptide 1-7 Pes-10 PF07149.11 OAG18278.1 - 7.8 5.4 6.5 12 4.8 6.5 1.2 1 0 0 1 1 1 0 Pes-10 DUF1857 PF08982.11 OAG18279.1 - 2e-58 196.4 0.0 2.2e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) CRM1_C PF08767.11 OAG18281.1 - 2.1e-133 444.4 4.8 2.1e-133 444.4 4.8 3.3 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OAG18281.1 - 1.7e-38 132.0 2.5 1.7e-38 132.0 2.5 3.9 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAG18281.1 - 1.2e-33 114.6 2.4 3.4e-33 113.1 2.4 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAG18281.1 - 3.1e-30 104.0 2.3 1.3e-29 102.0 0.9 3.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAG18281.1 - 2.8e-20 71.5 0.9 8.1e-20 70.0 0.9 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAG18281.1 - 1.7e-14 53.5 0.1 8.4e-14 51.2 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DRE2_N PF16803.5 OAG18281.1 - 0.067 13.4 0.1 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus MMS19_C PF12460.8 OAG18281.1 - 0.068 12.3 9.6 0.046 12.8 3.2 3.4 3 3 1 4 4 4 0 RNAPII transcription regulator C-terminal NTF2 PF02136.20 OAG18281.1 - 0.14 12.7 0.5 6.3 7.4 0.3 2.9 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DUF3385 PF11865.8 OAG18281.1 - 0.23 11.4 6.7 0.24 11.3 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OAG18281.1 - 0.25 12.0 2.0 7.6 7.2 0.0 3.9 4 0 0 4 4 3 0 Vacuolar 14 Fab1-binding region SPX PF03105.19 OAG18282.1 - 1e-22 81.6 15.2 4.2e-09 36.8 0.6 3.0 1 1 2 3 3 3 3 SPX domain MutS_II PF05188.17 OAG18282.1 - 0.02 15.2 0.2 0.04 14.2 0.1 1.5 1 1 0 1 1 1 0 MutS domain II GAS PF13851.6 OAG18282.1 - 0.098 12.0 4.7 0.16 11.3 4.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ABC1 PF03109.16 OAG18283.1 - 5.5e-34 116.9 0.0 8.8e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 OAG18283.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family HECT PF00632.25 OAG18284.1 - 3.5e-98 328.9 0.0 5e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAG18284.1 - 3.7e-33 113.3 21.9 3.8e-12 46.1 3.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 OAG18284.1 - 2.3e-20 72.8 0.0 5.6e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF2252 PF10009.9 OAG18285.1 - 0.24 10.4 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Aminotran_4 PF01063.19 OAG18286.1 - 6.4e-22 78.5 0.0 1.2e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Amino-transferase class IV DUF1360 PF07098.11 OAG18287.1 - 0.025 14.5 0.9 0.33 10.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) DUF2721 PF11026.8 OAG18287.1 - 0.32 10.9 3.4 4.5 7.2 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Kelch_5 PF13854.6 OAG18288.1 - 7.5e-12 45.0 12.5 2.9e-09 36.7 0.3 4.7 5 0 0 5 5 5 2 Kelch motif DUF2207 PF09972.9 OAG18288.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kelch_3 PF13415.6 OAG18288.1 - 0.036 14.4 15.1 0.15 12.4 0.1 6.0 7 0 0 7 7 7 0 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG18288.1 - 0.047 14.0 7.4 0.91 9.9 0.3 4.6 3 1 1 4 4 4 0 Kelch motif Kelch_1 PF01344.25 OAG18288.1 - 0.06 12.9 8.0 5.3 6.7 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Syndecan PF01034.20 OAG18288.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.6 OAG18288.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.4 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-CCHC_3 PF13917.6 OAG18289.1 - 2.1e-18 66.0 3.2 2.1e-18 66.0 3.2 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 OAG18289.1 - 0.2 11.8 1.3 0.35 11.0 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.24 OAG18290.1 - 4.2e-144 480.8 25.6 4.9e-144 480.5 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG18290.1 - 8.3e-24 84.2 34.0 7.3e-22 77.8 29.4 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1190 PF06693.11 OAG18290.1 - 0.2 12.1 0.1 0.44 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1190) DUF962 PF06127.11 OAG18290.1 - 0.92 9.6 3.4 0.71 10.0 0.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF2530 PF10745.9 OAG18290.1 - 1.2 9.4 7.6 0.21 11.8 2.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Steroid_dh PF02544.16 OAG18291.1 - 7.5e-21 74.7 0.3 2.2e-19 69.9 0.3 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAG18291.1 - 1.1e-05 25.1 0.7 2.1e-05 24.2 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) SKG6 PF08693.10 OAG18292.1 - 1.6e-08 33.8 4.8 4.1e-08 32.5 4.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAG18292.1 - 0.00028 20.8 2.8 0.00028 20.8 2.8 2.9 2 1 0 2 2 2 1 TMEM154 protein family CD34_antigen PF06365.12 OAG18292.1 - 0.00038 20.1 0.0 0.00063 19.4 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4448 PF14610.6 OAG18292.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PAP_PilO PF06864.12 OAG18292.1 - 0.0082 15.0 0.0 0.0082 15.0 0.0 1.8 2 1 0 2 2 2 1 Pilin accessory protein (PilO) DUF2207 PF09972.9 OAG18292.1 - 0.034 12.9 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 OAG18292.1 - 0.068 14.1 0.0 0.15 12.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PPR_2 PF13041.6 OAG18293.1 - 1.2e-25 89.5 0.4 1.5e-10 41.1 0.0 3.6 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 OAG18293.1 - 1.2e-13 50.9 0.1 5.2e-06 26.4 0.0 2.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 OAG18293.1 - 3.1e-08 33.3 1.2 1.6 9.2 0.0 5.7 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 OAG18293.1 - 1.1e-06 28.2 0.0 0.33 10.7 0.0 4.8 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 OAG18293.1 - 6.2e-06 25.7 0.0 0.00084 18.8 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP Osteoregulin PF07175.11 OAG18293.1 - 1.7 8.8 4.2 1.7 8.9 1.2 2.1 2 0 0 2 2 2 0 Osteoregulin cwf18 PF08315.12 OAG18294.1 - 6e-40 137.0 11.1 6e-40 137.0 11.1 1.9 1 1 1 2 2 2 1 cwf18 pre-mRNA splicing factor Nore1-SARAH PF16517.5 OAG18295.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain MDD_C PF18376.1 OAG18295.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Thiolase_N PF00108.23 OAG18296.1 - 1.2e-14 54.4 0.0 1.2e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG18296.1 - 4.5e-11 42.5 1.3 1.2e-10 41.1 0.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG18296.1 - 5.3e-06 26.2 0.0 0.0006 19.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG18296.1 - 8.5e-06 25.5 0.1 3.1e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain S4 PF01479.25 OAG18296.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain Ketoacyl-synt_C PF02801.22 OAG18296.1 - 0.05 13.6 1.4 2.5 8.1 0.0 3.2 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain SmaI PF17411.2 OAG18296.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease NCBP3 PF10309.9 OAG18297.1 - 7e-11 41.8 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Aldedh PF00171.22 OAG18298.1 - 6.3e-158 526.1 0.0 7.1e-158 525.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 OAG18299.1 - 9.8e-59 198.7 0.1 1.3e-58 198.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18299.1 - 3.3e-49 167.0 0.2 4.2e-49 166.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG18299.1 - 5.3e-07 29.7 0.1 1.1e-06 28.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG18299.1 - 0.031 13.7 0.1 0.21 11.0 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family AIM5 PF17050.5 OAG18301.1 - 3e-16 60.0 0.2 4.9e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 CHASE8 PF17152.4 OAG18301.1 - 0.015 15.5 0.1 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 Periplasmic sensor domain DUF4816 PF16086.5 OAG18301.1 - 0.038 13.9 0.3 0.07 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) Aldo_ket_red PF00248.21 OAG18302.1 - 2e-73 247.2 0.0 2.3e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavoprotein PF02441.19 OAG18303.1 - 1.4e-43 148.3 0.2 6.8e-43 146.1 0.2 1.8 1 1 0 1 1 1 1 Flavoprotein FG-GAP PF01839.23 OAG18304.1 - 0.14 12.4 2.1 0.51 10.5 2.1 2.0 1 0 0 1 1 1 0 FG-GAP repeat Pkinase PF00069.25 OAG18305.1 - 9.3e-61 205.5 0.0 1.3e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18305.1 - 6.8e-29 100.9 0.0 9.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG18305.1 - 7.5e-12 45.2 0.0 1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG18305.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.19 OAG18306.1 - 1e-30 106.4 0.3 3e-30 104.9 0.0 1.9 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 OAG18306.1 - 5.1e-18 64.9 0.0 3e-13 49.6 0.0 3.4 4 0 0 4 4 4 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1304 PF06993.12 OAG18306.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) SR-25 PF10500.9 OAG18308.1 - 0.27 10.8 10.2 0.41 10.2 10.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DENN PF02141.21 OAG18310.1 - 3.7e-57 193.3 0.1 7e-57 192.4 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAG18310.1 - 6.7e-17 62.0 0.0 1.7e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OAG18310.1 - 5.4e-14 51.9 0.6 1.5e-13 50.5 0.6 1.9 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 OAG18310.1 - 0.00029 21.1 5.2 0.0006 20.1 5.2 1.5 1 0 0 1 1 1 1 C1 domain Zf_RING PF16744.5 OAG18310.1 - 0.65 10.1 4.8 1.3 9.2 4.8 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 OAG18310.1 - 0.66 9.9 8.0 1.3 9.0 8.0 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 OAG18310.1 - 3.7 7.5 8.7 6.3 6.8 8.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF974 PF06159.13 OAG18311.1 - 7.3e-76 255.2 0.0 8.7e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) SET PF00856.28 OAG18312.1 - 1.2e-15 58.3 0.0 3.8e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OAG18312.1 - 0.033 14.8 0.0 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 SAF domain DUF1093 PF06486.11 OAG18312.1 - 0.13 12.9 0.1 0.27 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) DUF2408 PF10303.9 OAG18313.1 - 1.7e-47 161.3 14.8 3.3e-29 102.2 1.5 5.9 3 2 1 5 5 5 4 Protein of unknown function (DUF2408) DUF2920 PF11144.8 OAG18313.1 - 0.0053 16.0 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) DNA_photolyase PF00875.18 OAG18313.1 - 0.11 12.5 0.1 0.94 9.5 0.0 2.2 1 1 1 2 2 2 0 DNA photolyase HrpB7 PF09486.10 OAG18313.1 - 0.12 12.8 0.2 1.1 9.6 0.1 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 OAG18313.1 - 1.9 8.9 5.9 5.5 7.5 0.4 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_60s PF00428.19 OAG18314.1 - 2.1e-17 63.5 3.9 2.6e-17 63.2 3.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mito_carr PF00153.27 OAG18315.1 - 1.2e-42 143.7 5.4 3.6e-15 55.6 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Arabinose_trans PF04602.12 OAG18316.1 - 0.0043 16.0 0.0 0.0048 15.8 0.0 1.0 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Pyr_redox_2 PF07992.14 OAG18317.1 - 1.4e-62 211.6 0.3 2.4e-62 210.8 0.4 1.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG18317.1 - 2.8e-29 101.6 0.1 5.7e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG18317.1 - 1.1e-17 64.3 1.5 2.8e-17 63.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG18317.1 - 1.6e-15 57.2 3.5 3.9e-15 55.9 3.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG18317.1 - 3.9e-09 36.1 0.3 0.00083 18.6 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OAG18317.1 - 2.2e-05 24.0 0.3 0.0071 15.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG18317.1 - 0.0001 21.6 4.2 0.33 10.0 2.2 3.3 4 0 0 4 4 4 2 FAD binding domain DAO PF01266.24 OAG18317.1 - 0.0018 17.9 2.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG18317.1 - 0.0019 17.0 2.1 3.1 6.4 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 OAG18317.1 - 0.095 11.9 0.9 0.29 10.4 0.3 1.9 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAG18317.1 - 0.26 10.6 1.4 9.7 5.5 0.1 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAG18317.1 - 0.4 9.7 4.2 2.3 7.2 4.3 2.2 1 1 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 OAG18318.1 - 4.9e-23 81.5 0.1 1.4e-22 80.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18318.1 - 2.3e-06 27.6 16.6 3.8e-06 26.9 16.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 OAG18318.1 - 0.33 11.4 4.6 1 9.8 0.6 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DHquinase_I PF01487.15 OAG18319.1 - 8.5e-45 153.8 0.0 1.2e-44 153.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase 3HCDH_RFF PF18321.1 OAG18319.1 - 0.12 12.9 0.2 0.28 11.7 0.2 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Glutaredoxin PF00462.24 OAG18320.1 - 1.4e-15 57.3 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Shugoshin_N PF07558.11 OAG18321.1 - 0.68 9.9 4.9 0.55 10.2 1.5 2.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 OAG18321.1 - 0.72 10.0 3.5 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family peroxidase PF00141.23 OAG18322.1 - 6.2e-46 156.9 0.0 1e-45 156.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase fn3_3 PF14686.6 OAG18322.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II PTPS PF01242.19 OAG18323.1 - 0.038 13.9 0.4 0.084 12.8 0.4 1.5 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase MFS_1 PF07690.16 OAG18324.1 - 4.3e-37 127.8 26.9 4.3e-37 127.8 26.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_binding_3 PF13727.6 OAG18324.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.7 3 0 0 3 3 3 0 CoA-binding domain Peptidase_A8 PF01252.18 OAG18324.1 - 0.16 12.2 4.8 3.2 8.0 0.3 3.0 2 1 0 2 2 2 0 Signal peptidase (SPase) II PepSY_TM_like_2 PF16357.5 OAG18324.1 - 1.8 8.5 7.6 0.78 9.7 0.3 3.0 3 0 0 3 3 3 0 Putative PepSY_TM-like DUF1772 PF08592.11 OAG18324.1 - 3.4 8.0 11.2 46 4.3 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) DUF5315 PF17242.2 OAG18325.1 - 2.2e-24 85.1 3.9 5.7e-24 83.8 3.9 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Cluap1 PF10234.9 OAG18325.1 - 0.0059 16.0 2.0 0.0059 16.0 2.0 1.4 2 0 0 2 2 2 1 Clusterin-associated protein-1 Nucleo_P87 PF07267.11 OAG18325.1 - 0.034 13.0 7.9 0.045 12.6 7.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1178 PF06676.11 OAG18325.1 - 2 8.8 8.9 0.73 10.2 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Ribosom_S12_S23 PF00164.25 OAG18326.1 - 5.1e-51 171.1 0.6 6.3e-51 170.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ima1_N PF09779.9 OAG18327.1 - 4.2e-34 118.3 2.8 6.9e-34 117.6 2.8 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 OAG18327.1 - 0.07 13.2 3.5 3.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.20 OAG18327.1 - 0.17 12.0 3.0 0.093 12.8 0.6 1.9 2 0 0 2 2 2 0 Rubredoxin C1_2 PF03107.16 OAG18327.1 - 0.8 10.1 4.7 1.8 9.0 1.9 2.5 2 0 0 2 2 2 0 C1 domain zinc_ribbon_10 PF10058.9 OAG18327.1 - 4.5 7.1 5.0 40 4.0 1.9 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein KOW PF00467.29 OAG18328.1 - 0.017 15.1 2.2 0.042 13.8 2.2 1.7 1 0 0 1 1 1 0 KOW motif Alg14 PF08660.11 OAG18329.1 - 6.7e-54 182.5 0.0 3.4e-36 124.8 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like NACHT PF05729.12 OAG18330.1 - 0.00047 20.1 0.5 0.0055 16.6 0.5 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG18330.1 - 0.01 16.3 0.1 0.049 14.0 0.1 2.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 OAG18330.1 - 0.054 12.7 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OAG18330.1 - 0.13 12.6 0.0 0.56 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain NIF PF03031.18 OAG18331.1 - 4.3e-56 189.0 0.0 6.1e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 OAG18332.1 - 1e-58 198.8 1.2 1.6e-34 119.5 0.0 2.8 2 1 0 2 2 2 2 Initiation factor 2 subunit family adh_short_C2 PF13561.6 OAG18333.1 - 4.3e-34 118.1 0.0 6.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18333.1 - 2.3e-21 76.2 0.0 3.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 OAG18333.1 - 5.2e-12 45.7 0.0 9.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG18333.1 - 5.4e-05 22.9 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) KR PF08659.10 OAG18333.1 - 0.0034 17.3 0.0 0.0082 16.1 0.0 1.5 1 1 0 1 1 1 1 KR domain FtsJ PF01728.19 OAG18333.1 - 0.17 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase SUR7 PF06687.12 OAG18335.1 - 1.1e-41 142.9 21.5 1.3e-41 142.5 21.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 OAG18335.1 - 0.098 13.1 1.7 2.5 8.6 0.0 2.5 2 0 0 2 2 2 0 SCIMP protein CrgA PF06781.12 OAG18335.1 - 0.65 10.1 0.1 0.65 10.1 0.1 2.9 2 1 1 3 3 3 0 Cell division protein CrgA Fig1 PF12351.8 OAG18335.1 - 1.6 8.6 14.7 0.32 10.9 11.0 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 SKG6 PF08693.10 OAG18336.1 - 0.066 12.6 2.0 0.12 11.7 2.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 OAG18336.1 - 0.071 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PPI_Ypi1 PF07491.11 OAG18337.1 - 9.4e-25 86.2 8.3 4.3e-24 84.1 8.3 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor SURF2 PF05477.11 OAG18337.1 - 0.033 13.9 4.6 0.038 13.7 4.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 OAG18337.1 - 0.042 12.1 4.6 0.041 12.2 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DASH_Dad2 PF08654.10 OAG18338.1 - 1.8e-34 118.1 0.5 2.4e-34 117.7 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.11 OAG18339.1 - 5.2e-19 67.8 5.9 1.5e-18 66.4 5.9 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 OAG18339.1 - 5e-12 45.4 5.7 5e-12 45.4 5.7 2.5 2 0 0 2 2 2 1 Shugoshin C terminus CENP-N PF05238.13 OAG18341.1 - 3.8e-137 458.0 0.0 4.3e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 OAG18342.1 - 4.5e-10 39.5 14.7 4.5e-10 39.5 14.7 1.6 2 0 0 2 2 1 1 Basic region leucine zipper CREPT PF16566.5 OAG18342.1 - 0.0019 18.4 2.1 0.0033 17.6 2.1 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CLZ PF16526.5 OAG18342.1 - 0.014 15.8 2.7 0.014 15.8 2.7 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TSC22 PF01166.18 OAG18342.1 - 0.024 14.9 0.2 0.054 13.8 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Sin_N PF04801.13 OAG18342.1 - 0.042 13.1 8.2 0.056 12.6 8.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region bZIP_1 PF00170.21 OAG18342.1 - 0.042 13.9 9.0 0.1 12.7 9.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor FAM76 PF16046.5 OAG18342.1 - 0.14 11.4 5.4 0.23 10.8 5.4 1.2 1 0 0 1 1 1 0 FAM76 protein DUF5094 PF17015.5 OAG18342.1 - 0.2 11.8 2.7 0.29 11.2 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) XhlA PF10779.9 OAG18342.1 - 0.49 10.6 8.3 0.06 13.6 3.6 1.8 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_Maf PF03131.17 OAG18342.1 - 0.68 10.5 11.7 0.69 10.5 10.1 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF3395 PF11875.8 OAG18342.1 - 0.82 9.5 7.0 1.3 8.9 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Fib_alpha PF08702.10 OAG18342.1 - 1 9.5 5.8 1.7 8.9 5.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OAG18342.1 - 1.4 8.2 7.4 2 7.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAG18342.1 - 1.6 8.5 6.4 4.2 7.2 6.1 1.9 1 1 0 1 1 1 0 Septum formation initiator LCD1 PF09798.9 OAG18342.1 - 2.6 6.5 9.0 4.6 5.6 9.2 1.2 1 1 0 1 1 1 0 DNA damage checkpoint protein U1snRNP70_N PF12220.8 OAG18342.1 - 2.6 8.7 9.6 13 6.5 9.6 2.1 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal YabA PF06156.13 OAG18342.1 - 2.7 8.7 6.2 10 6.8 2.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Tctex-1 PF03645.13 OAG18343.1 - 4e-33 113.7 0.1 5.6e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 OAG18344.1 - 3.8e-14 52.9 6.1 8.6e-14 51.7 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DIE2_ALG10 PF04922.12 OAG18345.1 - 6.8e-121 404.3 11.4 8.6e-121 403.9 11.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 OAG18346.1 - 8.8e-31 106.6 0.0 1.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein RasGEF PF00617.19 OAG18349.1 - 1.1e-53 182.1 0.3 2.7e-53 180.8 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG18349.1 - 9.4e-13 48.3 0.0 3.9e-12 46.3 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 OAG18349.1 - 0.00012 21.9 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG18349.1 - 0.00049 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF4846 PF16138.5 OAG18349.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (4846) Rhodanese PF00581.20 OAG18350.1 - 7.7e-08 32.8 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF4423 PF14394.6 OAG18350.1 - 0.069 12.9 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Dioxygenase_C PF00775.21 OAG18351.1 - 8.1e-10 38.4 0.2 2.3e-09 36.9 0.2 1.8 1 1 0 1 1 1 1 Dioxygenase Ammonium_transp PF00909.21 OAG18353.1 - 6.1e-68 229.3 21.7 7e-68 229.1 21.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_16 PF10294.9 OAG18354.1 - 2.7e-47 160.7 0.0 3.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF43 PF01861.16 OAG18354.1 - 5.4e-05 22.5 0.0 7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 OAG18354.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DnaJ PF00226.31 OAG18355.1 - 2.3e-21 75.7 1.0 3.5e-21 75.1 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain SOTI PF17079.5 OAG18355.1 - 0.1 13.0 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Male-specific protein scotti Peptidase_M24 PF00557.24 OAG18356.1 - 8.6e-44 149.7 0.1 1.1e-43 149.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 OAG18356.1 - 0.00094 18.0 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 Pectinesterase YL1 PF05764.13 OAG18356.1 - 0.037 14.1 6.1 0.056 13.6 6.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF1351 PF07083.11 OAG18356.1 - 0.052 13.3 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) Med3 PF11593.8 OAG18356.1 - 0.68 9.1 1.8 1 8.5 1.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDC45 PF02724.14 OAG18356.1 - 7.4 4.7 6.2 11 4.2 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Porin_3 PF01459.22 OAG18357.1 - 1.7e-66 224.5 7.5 1.9e-66 224.3 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin MspA PF09203.11 OAG18357.1 - 0.0072 16.2 2.0 0.0072 16.2 2.0 2.0 2 1 0 2 2 2 1 MspA Chorismate_synt PF01264.21 OAG18358.1 - 2.4e-138 460.3 0.0 2.7e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Fungal_trans PF04082.18 OAG18359.1 - 4.8e-26 91.4 0.1 9e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18359.1 - 3.7e-07 30.2 8.8 7.1e-07 29.2 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRAL_TRIO_2 PF13716.6 OAG18360.1 - 5.1e-36 123.9 0.0 8.1e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 OAG18360.1 - 5.8e-21 74.9 0.0 1.1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 OAG18360.1 - 2.9e-05 23.8 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Tcf25 PF04910.14 OAG18361.1 - 1.2e-73 248.2 0.0 1.7e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_6 PF13174.6 OAG18361.1 - 0.11 13.2 1.1 0.47 11.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Nop53 PF07767.11 OAG18361.1 - 0.12 11.7 23.8 0.21 11.0 23.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SMP PF04927.12 OAG18361.1 - 0.14 12.7 3.4 0.4 11.2 3.4 1.8 1 0 0 1 1 1 0 Seed maturation protein Wbp11 PF09429.10 OAG18361.1 - 2.7 8.5 18.3 0.029 14.8 8.3 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 TFIIF_alpha PF05793.12 OAG18361.1 - 3.6 6.1 28.7 6.6 5.2 28.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPT6_acidic PF14632.6 OAG18361.1 - 3.7 8.2 24.0 0.62 10.7 15.3 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PP2C PF00481.21 OAG18362.1 - 1.5e-40 139.5 0.0 2.4e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAG18362.1 - 0.00074 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAG18362.1 - 0.023 14.6 0.0 0.29 11.0 0.0 2.4 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Peptidase_C70 PF12385.8 OAG18363.1 - 0.074 13.0 0.0 6.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 DUF212 PF02681.14 OAG18363.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Divergent PAP2 family MFS_1 PF07690.16 OAG18365.1 - 1.4e-12 47.3 26.2 1.4e-12 47.3 26.2 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily CHD5 PF04420.14 OAG18366.1 - 3.1e-57 192.9 2.1 3.6e-57 192.7 0.3 1.7 2 0 0 2 2 2 1 CHD5-like protein DUF2749 PF10907.8 OAG18366.1 - 8.2e-06 25.9 0.2 0.012 15.8 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2749) PPTA PF01239.22 OAG18367.1 - 1e-07 31.5 4.6 0.00012 21.7 0.1 3.9 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Tape_meas_lam_C PF09718.10 OAG18369.1 - 0.55 10.4 3.0 0.25 11.5 0.5 1.7 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zf-H2C2_2 PF13465.6 OAG18370.1 - 1.4e-12 47.4 10.0 7.5e-08 32.5 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 OAG18370.1 - 1.7e-12 47.0 12.8 3.7e-06 27.1 2.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG18370.1 - 1.1e-08 35.1 10.6 0.00041 20.9 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG18370.1 - 3.5e-08 33.3 5.8 0.00033 20.6 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG18370.1 - 6.7e-06 26.2 0.4 0.089 13.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG18370.1 - 3.2e-05 24.2 0.9 0.013 15.8 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 OAG18370.1 - 0.005 17.3 1.5 0.011 16.2 1.5 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 OAG18370.1 - 0.022 14.5 5.4 0.42 10.4 0.7 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG18370.1 - 0.044 14.1 1.4 0.089 13.1 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 OAG18370.1 - 0.36 11.1 2.8 17 5.8 0.1 2.4 1 1 1 2 2 2 0 LIM domain BRO1 PF03097.18 OAG18371.1 - 1.5e-126 422.4 2.0 7.8e-126 420.0 0.0 2.3 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG18371.1 - 2.7e-86 289.5 7.1 2.7e-86 289.5 7.1 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cytadhesin_P30 PF07271.11 OAG18371.1 - 0.041 13.5 1.7 0.072 12.7 1.7 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 SpoU_sub_bind PF08032.12 OAG18371.1 - 0.23 11.8 3.5 22 5.4 0.1 3.6 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding DUF148 PF02520.17 OAG18371.1 - 0.35 11.0 4.3 3.1 7.9 1.2 3.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 HMA PF00403.26 OAG18372.1 - 7.7e-16 58.3 0.3 9.3e-16 58.0 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 OAG18372.1 - 0.038 14.1 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fer2_BFD PF04324.15 OAG18372.1 - 0.08 13.3 0.3 0.18 12.2 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DJ-1_PfpI PF01965.24 OAG18373.1 - 1.2e-05 25.1 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Mito_carr PF00153.27 OAG18376.1 - 9e-65 214.6 0.7 3.8e-23 81.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG18376.1 - 0.0074 15.5 0.2 0.17 11.0 0.0 2.8 2 1 0 2 2 2 1 Gammaproteobacterial serine protease UCR_14kD PF02271.16 OAG18377.1 - 2.4e-45 152.6 0.6 3e-45 152.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HhH-GPD PF00730.25 OAG18378.1 - 1.4e-10 41.6 0.0 2.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.8 OAG18379.1 - 2e-10 40.7 5.1 6.6e-10 39.0 5.1 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 OAG18379.1 - 6.3e-08 32.7 0.4 0.087 12.9 0.0 3.8 2 2 1 3 3 3 3 Receptor L domain ToxS PF17323.2 OAG18379.1 - 0.14 11.8 0.2 6.7 6.4 0.0 2.7 3 0 0 3 3 3 0 Trans-membrane regulatory protein ToxS Anp1 PF03452.14 OAG18380.1 - 9.5e-108 359.6 0.0 1.2e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 G-patch PF01585.23 OAG18381.1 - 3.5e-11 42.8 1.2 3.5e-11 42.8 1.2 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAG18381.1 - 0.00054 20.0 0.6 0.00054 20.0 0.6 2.0 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 OAG18381.1 - 0.00089 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 OAG18382.1 - 9.1e-90 301.3 0.0 1.1e-89 301.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG18382.1 - 3.2e-14 53.6 0.6 2.3e-13 50.9 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OAG18382.1 - 0.00048 19.1 0.0 0.004 16.1 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 OAG18382.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 RTX C-terminal domain Fungal_trans_2 PF11951.8 OAG18384.1 - 3.4e-08 32.7 0.9 4.8e-08 32.2 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18384.1 - 3.7e-05 23.8 5.0 3.7e-05 23.8 5.0 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.12 OAG18386.1 - 4.9e-139 464.2 0.2 5.8e-139 464.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG18386.1 - 1.5e-54 185.5 0.0 2.8e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF3984 PF13136.6 OAG18387.1 - 3.5e-51 174.6 27.7 3.2e-41 141.8 15.2 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3984) DUF1068 PF06364.12 OAG18387.1 - 0.14 12.0 0.4 0.24 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Vpu PF00558.19 OAG18387.1 - 0.16 11.8 0.3 0.16 11.8 0.3 1.8 2 0 0 2 2 2 0 Vpu protein Y_phosphatase2 PF03162.13 OAG18389.1 - 4.4e-47 159.7 0.0 3.7e-44 150.2 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAG18389.1 - 1.3e-12 48.2 0.0 6.1e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OAG18389.1 - 0.00023 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG18389.1 - 0.0019 17.8 0.1 0.0029 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_transf_22 PF03901.17 OAG18390.1 - 2e-82 277.7 8.8 3.9e-82 276.7 8.8 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 OAG18392.1 - 3.6e-49 167.5 0.1 5.5e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18392.1 - 7.5e-24 84.4 0.1 8.2e-23 81.0 0.1 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG18392.1 - 0.0019 17.1 0.0 0.0058 15.5 0.0 1.9 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG18392.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HHH PF00633.23 OAG18393.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RR_TM4-6 PF06459.12 OAG18393.1 - 0.67 9.7 6.4 1 9.1 6.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 JmjC PF02373.22 OAG18394.1 - 4.9e-10 39.8 0.8 5.6e-09 36.4 0.8 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 OAG18394.1 - 2.8e-07 30.7 8.0 2.8e-07 30.7 8.0 2.8 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 OAG18394.1 - 0.0026 17.4 0.0 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.18 OAG18395.1 - 5.2e-45 153.7 20.5 7e-45 153.3 20.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Metallophos_2 PF12850.7 OAG18396.1 - 6.3e-11 42.7 0.0 8.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TTC5_OB PF16669.5 OAG18396.1 - 0.19 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain SUZ PF12752.7 OAG18397.1 - 9e-15 55.2 5.3 9e-15 55.2 5.3 4.5 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 OAG18397.1 - 1.6e-06 28.0 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain F-box-like PF12937.7 OAG18398.1 - 2.8e-05 23.9 0.1 7.8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAG18398.1 - 0.00037 20.4 0.0 0.00097 19.0 0.0 1.7 2 0 0 2 2 2 1 F-box F-box PF00646.33 OAG18398.1 - 0.0031 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain ATG27 PF09451.10 OAG18399.1 - 2.6e-89 299.6 0.1 3.2e-89 299.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAG18399.1 - 5.8e-05 23.2 0.9 0.067 13.3 0.1 3.0 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat DUF2457 PF10446.9 OAG18399.1 - 0.15 11.2 13.2 0.23 10.5 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Con-6 PF10346.9 OAG18401.1 - 3.4e-33 113.3 8.2 1.1e-16 60.5 0.9 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF1542 PF07564.11 OAG18401.1 - 0.014 15.5 2.7 2.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glyco_transf_8C PF08437.10 OAG18401.1 - 0.02 15.0 0.3 3.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Rotamase_3 PF13616.6 OAG18401.1 - 0.07 13.7 0.7 0.087 13.4 0.7 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain DGF-1_C PF11040.8 OAG18401.1 - 0.091 12.8 0.4 12 5.9 0.0 2.1 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SpoIIIAH PF12685.7 OAG18401.1 - 0.33 10.7 5.8 11 5.8 5.8 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein PAC4 PF16093.5 OAG18402.1 - 1.3e-21 76.5 0.0 1.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 OAG18403.1 - 7.2e-88 294.3 0.0 9.5e-88 293.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 OAG18403.1 - 0.0033 18.1 0.0 0.097 13.3 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG18403.1 - 0.013 16.2 0.0 0.05 14.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG18403.1 - 0.031 15.0 0.0 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAG18403.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 OAG18404.1 - 0.03 14.4 9.3 0.068 13.3 9.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 OAG18406.1 - 2.7e-20 71.8 0.2 3.3e-20 71.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 OAG18406.1 - 0.00072 20.0 9.6 0.001 19.6 9.6 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 AstE_AspA PF04952.14 OAG18408.1 - 3.1e-31 108.5 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Lectin_C PF00059.21 OAG18410.1 - 0.012 16.4 0.0 0.021 15.6 0.0 1.3 1 0 0 1 1 1 0 Lectin C-type domain GMC_oxred_N PF00732.19 OAG18411.1 - 7.3e-50 170.0 0.0 9.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG18411.1 - 5.9e-37 127.4 0.0 1.1e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG18411.1 - 0.00025 20.8 1.0 0.3 10.6 0.6 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG18411.1 - 0.002 18.3 0.3 0.006 16.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG18411.1 - 0.0021 17.2 0.2 0.0032 16.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG18411.1 - 0.0066 15.7 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG18411.1 - 0.03 13.0 0.2 0.84 8.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAG18411.1 - 0.058 12.2 0.2 0.089 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG18411.1 - 0.073 12.3 0.4 6.8 5.8 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG18411.1 - 0.22 10.8 0.2 0.76 9.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 OAG18411.1 - 0.28 9.7 0.0 12 4.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HSP20 PF00011.21 OAG18412.1 - 1.4e-14 54.0 0.1 1.9e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG18412.1 - 4e-05 23.1 0.1 0.00023 20.7 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 OAG18412.1 - 0.097 12.8 0.0 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal Polyketide_cyc2 PF10604.9 OAG18413.1 - 3.5e-08 33.8 0.1 3.9e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cu-oxidase_3 PF07732.15 OAG18414.1 - 1e-41 141.7 0.7 1.4e-40 138.0 0.3 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG18414.1 - 7.2e-40 135.9 5.9 1.1e-36 125.6 1.2 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG18414.1 - 1e-30 106.9 0.0 2.3e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase MFS_1 PF07690.16 OAG18415.1 - 4.7e-36 124.4 22.1 7.5e-36 123.8 22.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG18415.1 - 0.0001 22.0 0.9 0.00024 20.8 0.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Ceramidase PF05875.12 OAG18415.1 - 0.036 13.5 2.1 0.32 10.4 0.2 2.5 2 1 0 2 2 2 0 Ceramidase MASE3 PF17159.4 OAG18415.1 - 0.15 11.6 6.6 0.35 10.5 2.0 3.1 2 1 1 3 3 3 0 Membrane-associated sensor domain CoA_trans PF01144.23 OAG18416.1 - 8.6e-99 329.3 3.4 1.4e-59 201.1 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAG18416.1 - 4.7e-05 23.4 0.9 0.00022 21.2 0.1 2.0 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 OAG18416.1 - 0.0001 20.8 0.2 0.00025 19.5 0.0 1.6 2 0 0 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter Zn_clus PF00172.18 OAG18417.1 - 6.6e-08 32.5 7.0 1.4e-07 31.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 OAG18418.1 - 4.1e-05 23.2 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OAG18418.1 - 8.2e-05 23.1 0.0 8.2e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.15 OAG18419.1 - 2.4e-77 259.0 0.0 1.1e-76 256.9 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2207 PF09972.9 OAG18420.1 - 0.011 14.6 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 OAG18420.1 - 0.35 11.2 4.4 5.2 7.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Orf78 PF06024.12 OAG18420.1 - 1.1 9.6 3.0 4.3 7.7 3.0 2.1 1 1 0 1 1 1 0 Orf78 (ac78) Bcr-Abl_Oligo PF09036.10 OAG18422.1 - 0.024 14.6 0.3 0.064 13.3 0.3 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain ANAPC4_WD40 PF12894.7 OAG18423.1 - 0.00085 19.6 0.0 0.88 9.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG18423.1 - 0.0043 17.9 0.6 2 9.4 0.0 3.7 2 1 1 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.11 OAG18423.1 - 0.078 12.8 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EIIBC-GUT_N PF03612.14 OAG18424.1 - 0.042 13.6 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CYSTM PF12734.7 OAG18424.1 - 0.26 11.6 1.9 0.51 10.7 1.9 1.4 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Acetyltransf_7 PF13508.7 OAG18425.1 - 0.0087 16.5 0.0 0.028 14.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG18425.1 - 0.013 15.6 0.8 0.044 13.9 0.0 2.3 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG18425.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG18425.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 OAG18426.1 - 2.6e-66 222.4 1.1 2.9e-66 222.2 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG18426.1 - 1.6e-12 47.7 0.1 2.2e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAG18426.1 - 3e-12 46.4 1.2 5.9e-07 29.0 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG18426.1 - 5e-12 45.7 0.0 5.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG18426.1 - 1.1e-09 38.0 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG18426.1 - 4.6e-08 33.1 0.0 8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG18426.1 - 3.9e-07 29.7 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAG18426.1 - 0.00018 21.1 0.0 0.005 16.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG18426.1 - 0.03 13.9 0.4 0.1 12.1 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 OAG18426.1 - 0.088 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NTPase_1 PF03266.15 OAG18426.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 NTPase DUF4045 PF13254.6 OAG18427.1 - 2e-121 406.6 40.5 2e-121 406.6 40.5 5.5 4 1 1 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 OAG18427.1 - 0.00029 20.7 0.0 0.27 11.1 0.0 3.2 3 0 0 3 3 3 2 Gelsolin repeat Glyco_hydro_11 PF00457.17 OAG18428.1 - 6.8e-61 205.0 15.7 8e-61 204.8 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ribosomal_L2_C PF03947.18 OAG18429.1 - 1.5e-41 141.5 3.6 2.5e-41 140.8 3.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAG18429.1 - 1.7e-14 53.6 0.1 4e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ANAPC4 PF12896.7 OAG18430.1 - 1e-57 194.9 2.0 1.6e-57 194.3 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OAG18430.1 - 4.4e-25 87.8 0.0 1.7e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF957 PF06117.11 OAG18430.1 - 0.11 12.1 0.1 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Mg_trans_NIPA PF05653.14 OAG18431.1 - 1.5e-103 346.0 15.9 1.7e-103 345.8 15.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG18431.1 - 6e-05 23.2 6.8 6e-05 23.2 6.8 4.0 3 1 0 3 3 3 1 EamA-like transporter family DUF2420 PF10336.9 OAG18432.1 - 2.2e-27 95.2 0.0 6.1e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 OAG18433.1 - 2.4e-17 63.2 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RPM2 PF08579.11 OAG18433.1 - 1.7e-05 25.2 2.0 0.00037 20.9 1.7 2.6 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) Clat_adaptor_s PF01217.20 OAG18433.1 - 2.6e-05 24.2 0.3 4.4e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_125 PF06824.11 OAG18435.1 - 4.6e-183 608.8 0.0 5.5e-183 608.6 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DASH_Dam1 PF08653.10 OAG18435.1 - 0.056 13.3 0.2 0.29 11.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Desulfoferrod_N PF06397.12 OAG18437.1 - 0.044 13.4 0.6 0.068 12.8 0.6 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Trp_oprn_chp PF09534.10 OAG18437.1 - 0.084 12.7 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_61 PF03443.14 OAG18438.1 - 3.3e-63 213.4 1.0 3.8e-63 213.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 OAG18439.1 - 2.3e-10 40.2 1.1 0.00043 19.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Peptidase_S9 PF00326.21 OAG18439.1 - 0.029 13.9 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_8 PF13450.6 OAG18439.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG18439.1 - 0.1 11.8 0.0 0.93 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XRCC4 PF06632.12 OAG18439.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spt20 PF12090.8 OAG18442.1 - 1.2e-47 162.5 0.0 1.2e-47 162.5 0.0 7.6 3 1 3 6 6 6 1 Spt20 family DnaJ PF00226.31 OAG18443.1 - 6e-16 58.3 0.1 1.5e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Oxidored_q6 PF01058.22 OAG18444.1 - 8.6e-23 80.6 0.1 1.5e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fungal_trans PF04082.18 OAG18445.1 - 8.4e-09 34.8 2.4 1.2e-08 34.3 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 OAG18446.1 - 8.9e-22 77.5 8.5 8.9e-22 77.5 8.5 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG18446.1 - 3e-13 50.2 0.1 2.3e-10 40.8 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG18446.1 - 5.8e-10 39.2 0.0 2.9e-05 24.1 0.0 2.7 1 1 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 OAG18446.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain CVNH PF08881.10 OAG18447.1 - 2.7e-34 117.9 1.1 5.3e-34 116.9 1.1 1.5 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 OAG18447.1 - 3.8e-13 49.3 0.0 6.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.15 OAG18447.1 - 1.1e-06 28.3 27.2 1.1e-06 28.3 27.2 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF3824 PF12868.7 OAG18447.1 - 0.0013 19.5 1.6 0.0013 19.5 1.6 2.6 3 0 0 3 3 3 1 Domain of unknwon function (DUF3824) TraT PF05818.12 OAG18447.1 - 0.021 14.5 1.3 0.021 14.5 1.3 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein ATPase_gene1 PF09527.10 OAG18447.1 - 2.5 8.3 7.7 3.9 7.7 7.7 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter AMP-binding PF00501.28 OAG18448.1 - 1.6e-62 211.5 2.5 2.2e-25 89.1 1.4 4.7 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 OAG18448.1 - 5.7e-12 46.4 0.2 5.7e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 OAG18448.1 - 0.0042 17.1 0.3 0.01 15.8 0.3 1.6 1 0 0 1 1 1 1 Gas vesicle protein G 4HBT_3 PF13622.6 OAG18449.1 - 2e-82 277.2 0.5 2.4e-82 276.9 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG18449.1 - 3e-27 95.1 0.0 1.8e-13 50.5 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Crp PF00325.20 OAG18452.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Tubulin_3 PF14881.6 OAG18453.1 - 2.6e-76 255.3 0.0 7.4e-76 253.9 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Prp18 PF02840.15 OAG18453.1 - 2e-31 109.0 0.0 2e-31 109.0 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain Misat_Tub_SegII PF10644.9 OAG18453.1 - 5.5e-23 81.5 0.6 2.6e-22 79.4 0.0 2.4 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain PRP4 PF08799.11 OAG18453.1 - 2.7e-11 42.8 0.7 2.7e-11 42.8 0.7 4.0 4 0 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Tubulin PF00091.25 OAG18453.1 - 0.033 14.4 0.0 0.099 12.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain SAP18 PF06487.12 OAG18454.1 - 1.8e-50 170.8 0.0 2.1e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) zf-C2H2 PF00096.26 OAG18455.1 - 7.8e-06 26.1 10.0 0.003 17.9 1.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG18455.1 - 5.1e-05 23.8 10.6 0.026 15.3 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG18455.1 - 0.06 13.6 0.1 3.7 7.9 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG18455.1 - 0.083 12.9 0.9 0.083 12.9 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Abhydrolase_6 PF12697.7 OAG18456.1 - 0.0035 18.0 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 OAG18456.1 - 0.037 13.2 0.0 0.07 12.3 0.0 1.6 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OAG18456.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAG18456.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Palm_thioest PF02089.15 OAG18456.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 OAG18456.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pyr_redox_2 PF07992.14 OAG18458.1 - 3.7e-10 39.5 0.0 1.4e-06 27.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG18458.1 - 1.3e-09 37.0 0.2 1.4e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG18458.1 - 1.9e-05 24.1 0.4 0.0015 17.8 0.5 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG18458.1 - 4.9e-05 22.6 0.1 0.00071 18.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG18458.1 - 0.00024 21.2 0.1 0.00059 20.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG18458.1 - 0.0005 20.1 0.0 1.4 8.9 0.0 3.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG18458.1 - 0.0007 20.1 0.3 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG18458.1 - 0.0037 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG18458.1 - 0.015 15.7 0.1 0.053 14.0 0.0 2.1 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG18458.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG18458.1 - 0.055 13.1 0.6 5 6.6 0.0 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OAG18458.1 - 0.12 12.6 1.4 26 5.1 0.0 3.7 4 0 0 4 4 4 0 TrkA-N domain Endonuc-BglII PF09195.11 OAG18458.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII GMC_oxred_N PF00732.19 OAG18459.1 - 1.3e-28 100.3 0.2 2e-28 99.6 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG18459.1 - 7.9e-18 65.4 0.1 1.5e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase HI0933_like PF03486.14 OAG18459.1 - 1.1e-07 31.0 0.1 0.00049 18.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAG18459.1 - 1.8e-07 30.7 0.1 1.8e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG18459.1 - 1.8e-05 24.2 0.0 0.00044 19.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG18459.1 - 4.6e-05 22.8 0.0 0.0001 21.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG18459.1 - 0.00023 20.9 0.9 0.0053 16.4 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG18459.1 - 0.00026 21.2 0.0 0.00071 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG18459.1 - 0.0003 20.2 0.3 0.00052 19.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG18459.1 - 0.0012 18.2 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG18459.1 - 0.012 14.8 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAG18459.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAG18459.1 - 0.039 13.0 0.1 0.062 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC2_membrane_3 PF12698.7 OAG18459.1 - 0.076 12.1 0.1 0.53 9.3 0.1 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein EndoU_bacteria PF14436.6 OAG18459.1 - 0.095 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial EndoU nuclease Pyr_redox PF00070.27 OAG18459.1 - 0.098 13.2 0.0 8.8 7.0 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG18460.1 - 4.8e-33 114.3 0.0 6.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18460.1 - 1.3e-30 106.7 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18460.1 - 2.7e-10 40.5 0.1 4.1e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG18460.1 - 0.00053 19.7 1.4 0.0039 16.9 0.3 2.5 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 OAG18460.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG18460.1 - 0.056 12.9 0.0 10 5.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_trans_2_3 PF13632.6 OAG18461.1 - 7.9e-18 65.1 0.6 7.9e-18 65.1 0.6 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG18461.1 - 8.2e-16 58.6 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG18461.1 - 7.4e-13 48.3 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG18461.1 - 3.6e-12 46.4 0.0 6.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAG18461.1 - 5.4e-08 31.8 0.9 0.00028 19.5 0.0 2.2 1 1 1 2 2 2 2 Cellulose synthase nec1 PF10379.9 OAG18462.1 - 0.1 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 TMEM144 PF07857.12 OAG18463.1 - 0.036 13.0 0.2 0.051 12.5 0.2 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Bax1-I PF01027.20 OAG18463.1 - 0.047 13.5 3.0 0.1 12.4 3.0 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 TMEM100 PF16311.5 OAG18463.1 - 0.074 12.6 0.3 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 100 Claudin_2 PF13903.6 OAG18463.1 - 0.17 11.6 2.7 0.17 11.6 1.4 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Vpu PF00558.19 OAG18466.1 - 0.055 13.3 1.9 0.37 10.6 0.7 2.6 2 1 0 2 2 2 0 Vpu protein Sugar_tr PF00083.24 OAG18467.1 - 3.1e-87 293.3 21.7 3.5e-87 293.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG18467.1 - 1.4e-16 60.4 22.5 1.9e-16 60.0 19.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily AT_hook PF02178.19 OAG18469.1 - 0.3 11.1 13.6 0.11 12.4 1.7 3.3 2 0 0 2 2 2 0 AT hook motif Pan3_PK PF18101.1 OAG18471.1 - 1.1e-54 184.2 0.1 3.9e-54 182.4 0.1 1.9 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAG18471.1 - 5.6e-06 25.9 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 OAG18471.1 - 0.001 18.9 0.7 0.0017 18.2 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDP-OH_P_transf PF01066.21 OAG18472.1 - 1.6e-13 51.2 0.3 1.6e-13 51.2 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DEAD PF00270.29 OAG18473.1 - 1e-49 168.7 0.1 2.1e-49 167.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG18473.1 - 4.6e-31 107.4 0.2 1.5e-28 99.4 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 OAG18473.1 - 0.00082 18.3 1.7 0.0012 17.8 0.7 1.8 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 OAG18473.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IBR PF01485.21 OAG18474.1 - 3.9e-11 43.0 20.1 2.3e-08 34.1 4.1 3.3 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain PAP_central PF04928.17 OAG18475.1 - 1.8e-100 335.0 0.0 2.3e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAG18475.1 - 9.9e-51 171.8 0.0 1.5e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAG18475.1 - 1.5e-10 41.3 0.0 4.6e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG18475.1 - 0.0072 16.4 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase YlbD_coat PF14071.6 OAG18475.1 - 0.065 13.5 5.1 0.16 12.2 0.0 2.7 3 0 0 3 3 3 0 Putative coat protein 2_5_RNA_ligase2 PF13563.6 OAG18476.1 - 3.2e-31 108.3 0.2 3.8e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Abhydrolase_1 PF00561.20 OAG18477.1 - 2.3e-09 37.3 0.1 7e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG18477.1 - 0.0045 17.6 0.1 0.0058 17.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG18477.1 - 0.018 14.3 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Flavin_Reduct PF01613.18 OAG18478.1 - 3.8e-16 59.5 0.0 5.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain FTR1 PF03239.14 OAG18480.1 - 1.9e-85 286.8 5.4 2.2e-85 286.5 5.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2140 PF09911.9 OAG18480.1 - 0.2 11.2 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4131 PF13567.6 OAG18480.1 - 0.75 9.4 6.5 9.9 5.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) B12D PF06522.11 OAG18480.1 - 4.5 7.1 5.2 5.5 6.9 0.2 3.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cu-oxidase_2 PF07731.14 OAG18481.1 - 1.6e-46 157.4 6.9 7.5e-42 142.3 0.7 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG18481.1 - 3.8e-44 149.5 6.2 7.6e-42 142.1 1.3 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG18481.1 - 2.6e-40 138.1 2.3 2.3e-35 122.1 0.4 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG18481.1 - 0.0031 17.6 0.0 19 5.4 0.0 3.9 4 1 0 4 4 4 1 Cupredoxin-like domain Monooxygenase_B PF04744.12 OAG18481.1 - 0.073 11.9 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 Monooxygenase subunit B protein LigB PF02900.18 OAG18482.1 - 4.5e-33 114.5 0.0 5.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DeoC PF01791.9 OAG18482.1 - 0.16 11.5 0.1 0.54 9.8 0.0 1.8 2 0 0 2 2 2 0 DeoC/LacD family aldolase Presenilin PF01080.17 OAG18483.1 - 0.64 8.7 4.3 0.73 8.5 4.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAG18483.1 - 1.7 8.4 10.3 1.9 8.2 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 OAG18483.1 - 2.5 8.4 11.5 5.5 7.3 11.5 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated OMPdecase PF00215.24 OAG18484.1 - 2.7e-77 259.3 0.0 3.3e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Cue1_U7BR PF18499.1 OAG18484.1 - 0.17 11.9 0.1 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Methyltr_RsmB-F PF01189.17 OAG18485.1 - 8.8e-19 67.9 0.0 8e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F COR PF16095.5 OAG18485.1 - 0.051 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain HWE_HK PF07536.14 OAG18485.1 - 0.12 13.1 1.4 2.1 9.1 0.0 2.7 2 0 0 2 2 2 0 HWE histidine kinase INCENP_ARK-bind PF03941.15 OAG18485.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region SAD_SRA PF02182.17 OAG18486.1 - 1.4e-06 28.0 0.1 3.4e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 SAD/SRA domain AA_permease_2 PF13520.6 OAG18487.1 - 2.9e-45 154.9 49.9 3.8e-45 154.5 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG18487.1 - 2.2e-24 85.9 43.3 2.7e-24 85.6 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease 2-Hacid_dh_C PF02826.19 OAG18489.1 - 3.7e-36 124.1 0.0 5.8e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG18489.1 - 1.7e-21 76.3 0.0 2.3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAG18489.1 - 0.012 16.1 0.0 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain PHD PF00628.29 OAG18490.1 - 0.0038 17.1 8.7 0.0089 15.9 8.7 1.7 1 0 0 1 1 1 1 PHD-finger GFO_IDH_MocA PF01408.22 OAG18492.1 - 1e-17 65.1 0.0 1.7e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 OAG18493.1 - 6.1e-29 101.1 33.3 6.1e-29 101.1 33.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_C12 PF01088.21 OAG18494.1 - 2.5e-47 161.4 0.0 2.8e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cupin_2 PF07883.11 OAG18495.1 - 5.8e-16 58.0 0.8 8.1e-16 57.5 0.8 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG18495.1 - 0.00078 19.1 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG18495.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG18495.1 - 0.0047 17.1 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 OAG18495.1 - 0.046 13.6 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain TFIIIC_delta PF12657.7 OAG18496.1 - 0.023 14.6 1.5 0.052 13.5 1.2 1.7 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term CHRD PF07452.12 OAG18497.1 - 2.1e-15 57.7 0.1 2.7e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 CHRD domain TetR_C_5 PF08360.11 OAG18497.1 - 0.25 11.5 1.3 0.39 10.9 1.3 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region PhoD PF09423.10 OAG18498.1 - 2.9e-115 385.0 6.3 3.5e-115 384.7 6.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAG18498.1 - 4e-32 110.6 0.1 1.1e-31 109.2 0.1 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAG18498.1 - 0.0034 17.9 1.4 0.0034 17.9 1.4 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain FAD_binding_3 PF01494.19 OAG18499.1 - 1.2e-21 77.3 0.0 2.3e-21 76.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG18499.1 - 6.2e-05 22.2 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG18499.1 - 0.0086 15.3 0.2 0.53 9.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG18499.1 - 0.015 15.5 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG18499.1 - 0.049 12.7 0.0 2.5 7.1 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Glyco_hydro_12 PF01670.16 OAG18500.1 - 1.9e-46 158.8 7.2 2.4e-46 158.4 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 OAG18500.1 - 0.00016 22.0 1.0 0.00038 20.8 0.3 1.9 1 1 0 1 1 1 1 Bacteriophage A118-like holin, Hol118 UBM PF14377.6 OAG18501.1 - 0.0038 16.6 1.9 3.3 7.3 0.2 3.7 3 0 0 3 3 3 2 Ubiquitin binding region F-box PF00646.33 OAG18502.1 - 3.7e-06 26.7 0.6 7e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 F-box domain DUF4616 PF15394.6 OAG18502.1 - 0.018 14.0 2.8 0.028 13.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) F-box-like PF12937.7 OAG18502.1 - 0.15 12.0 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like Host_attach PF10116.9 OAG18502.1 - 1.4 9.5 5.0 2.5 8.7 0.0 2.8 2 1 0 2 2 2 0 Protein required for attachment to host cells His_Phos_2 PF00328.22 OAG18503.1 - 1.6e-14 54.1 0.0 2.5e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.6 OAG18504.1 - 3.7e-29 100.7 4.3 4e-09 36.5 0.0 8.0 5 3 3 8 8 8 6 PPR repeat family PPR_3 PF13812.6 OAG18504.1 - 1.4e-21 76.3 0.0 1.1e-08 35.0 0.0 4.9 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 OAG18504.1 - 4.2e-15 54.8 3.1 0.00074 19.6 0.0 6.8 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 OAG18504.1 - 2.2e-14 53.3 0.2 0.0018 17.7 0.0 4.4 2 1 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG18504.1 - 2.5e-09 36.7 0.0 4.2e-05 23.2 0.0 5.8 8 0 0 8 8 8 1 PPR repeat ECSIT PF06239.11 OAG18504.1 - 0.0031 16.7 0.0 0.11 11.6 0.0 2.7 2 1 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.6 OAG18504.1 - 0.0063 17.2 0.3 14 6.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ACP_PD PF04336.12 OAG18504.1 - 0.82 10.1 3.3 8 6.9 0.1 3.7 5 0 0 5 5 5 0 Acyl carrier protein phosphodiesterase bZIP_1 PF00170.21 OAG18505.1 - 4.9e-07 29.7 10.5 4.9e-07 29.7 10.5 2.6 3 0 0 3 3 3 1 bZIP transcription factor DUF3037 PF11236.8 OAG18505.1 - 0.13 12.7 4.1 1.1 9.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Spt20 PF12090.8 OAG18505.1 - 3.3 7.2 24.9 0.14 11.8 16.0 2.5 2 0 0 2 2 2 0 Spt20 family FAM76 PF16046.5 OAG18505.1 - 9.4 5.5 21.0 15 4.8 21.0 1.2 1 0 0 1 1 1 0 FAM76 protein c-SKI_SMAD_bind PF08782.10 OAG18507.1 - 0.0094 16.2 0.2 0.013 15.7 0.2 1.2 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Methyltransf_20 PF12147.8 OAG18507.1 - 0.016 14.4 0.4 0.023 13.9 0.4 1.2 1 0 0 1 1 1 0 Putative methyltransferase NST1 PF13945.6 OAG18507.1 - 0.028 14.5 3.3 0.034 14.2 3.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Cytochrom_B561 PF03188.16 OAG18508.1 - 4.9e-06 26.7 12.7 8.4e-06 26.0 12.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAG18508.1 - 0.013 15.3 7.5 0.026 14.3 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Gaa1 PF04114.14 OAG18508.1 - 0.056 12.5 0.5 0.07 12.1 0.5 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component CEND1 PF15677.5 OAG18508.1 - 0.13 12.8 0.1 0.22 12.0 0.1 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Tetraspanin PF00335.20 OAG18508.1 - 0.22 11.2 1.5 0.37 10.5 1.5 1.5 1 1 0 1 1 1 0 Tetraspanin family Mfp-3 PF04202.13 OAG18508.1 - 3.9 7.9 7.6 0.68 10.4 2.8 2.2 2 0 0 2 2 2 0 Foot protein 3 DUF4199 PF13858.6 OAG18508.1 - 7.3 7.0 16.1 1 9.8 4.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) PfkB PF00294.24 OAG18509.1 - 1.8e-72 244.2 1.8 2e-72 244.1 1.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG18509.1 - 2.6e-08 33.6 0.0 8.2e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 OAG18510.1 - 1.8e-68 231.1 0.0 3.3e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OAG18510.1 - 2.2e-17 64.0 2.9 5.3e-17 62.7 2.9 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 zf-C2H2 PF00096.26 OAG18511.1 - 0.032 14.7 4.0 0.032 14.7 4.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type KRAB PF01352.27 OAG18512.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 KRAB box Glyco_hydro_76 PF03663.14 OAG18513.1 - 5.8e-145 483.4 11.9 6.7e-145 483.2 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 EHN PF06441.12 OAG18514.1 - 1.4e-31 109.0 0.5 3.4e-31 107.8 0.5 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG18514.1 - 2.5e-10 40.5 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG18514.1 - 0.0033 18.1 0.8 0.011 16.3 0.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3327 PF11806.8 OAG18516.1 - 0.045 14.5 0.1 0.074 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Ribosomal_S9 PF00380.19 OAG18520.1 - 4.8e-42 143.3 0.2 9e-42 142.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PDEase_II PF02112.15 OAG18521.1 - 2.5e-47 161.6 0.0 4.8e-23 81.8 0.1 3.3 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II EF1G PF00647.19 OAG18521.1 - 2.6e-45 152.9 0.1 5.6e-45 151.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 OAG18521.1 - 7.7e-13 48.5 0.0 2.1e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG18521.1 - 1.8e-12 47.4 0.0 5.4e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG18521.1 - 5.2e-10 39.2 0.6 1.4e-09 37.8 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG18521.1 - 9e-07 29.2 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG18521.1 - 0.00039 20.6 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG18521.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAG18521.1 - 0.027 14.3 0.0 9.5 6.1 0.0 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.27 OAG18521.1 - 0.087 12.8 1.6 0.41 10.6 0.6 2.5 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily CortBP2 PF09727.9 OAG18523.1 - 7 6.5 22.6 12 5.7 22.6 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 MAS20 PF02064.15 OAG18523.1 - 7.4 6.7 9.6 15 5.7 9.6 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor MatE PF01554.18 OAG18525.1 - 7.8e-56 188.2 33.1 3.1e-34 118.0 13.0 2.3 2 0 0 2 2 2 2 MatE DUF4512 PF14975.6 OAG18525.1 - 0.17 12.6 0.2 0.47 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RTA1 PF04479.13 OAG18526.1 - 3.9e-65 219.3 3.2 3.9e-65 219.3 3.2 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF1980 PF09323.10 OAG18526.1 - 0.051 13.5 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GPI2 PF06432.11 OAG18526.1 - 1.5 8.2 8.8 2 7.8 0.1 2.5 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase Fungal_trans_2 PF11951.8 OAG18527.1 - 7.3e-10 38.2 0.8 1.3e-09 37.4 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18527.1 - 1.4e-09 37.9 8.2 2.3e-09 37.2 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBX PF00789.20 OAG18528.1 - 1.1e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAG18528.1 - 2.1e-09 37.0 0.2 5.1e-09 35.8 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 OAG18528.1 - 0.0011 18.3 4.6 0.0016 17.7 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Med19 PF10278.9 OAG18528.1 - 0.16 11.9 2.5 0.28 11.1 2.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CAF-1_p150 PF11600.8 OAG18528.1 - 0.17 11.6 16.8 0.28 10.9 16.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal U1snRNP70_N PF12220.8 OAG18528.1 - 2.5 8.8 9.1 7.1 7.3 9.1 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4449 PF14613.6 OAG18528.1 - 2.5 8.2 8.5 5 7.2 8.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF3445 PF11927.8 OAG18530.1 - 1.1e-35 123.3 0.2 4.7e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) TnpW PF14202.6 OAG18530.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW DUF2183 PF09949.9 OAG18531.1 - 7.4e-32 109.6 0.0 1.9e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GAT PF03127.14 OAG18532.1 - 4.5e-17 62.1 0.2 1.1e-16 60.9 0.2 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 OAG18532.1 - 0.00099 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 VHS domain F5_F8_type_C PF00754.25 OAG18534.1 - 1.1e-06 28.8 1.9 1.7e-06 28.2 0.9 1.9 2 0 0 2 2 2 1 F5/8 type C domain Trehalase PF01204.18 OAG18534.1 - 0.006 15.5 0.2 0.01 14.7 0.2 1.4 1 0 0 1 1 1 1 Trehalase MMS1_N PF10433.9 OAG18535.1 - 4.3e-128 428.0 0.0 8.8e-128 427.0 0.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG18535.1 - 2e-86 290.3 0.0 8.4e-86 288.2 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region SDA1 PF05285.12 OAG18536.1 - 1.3e-89 301.1 45.0 1.3e-89 301.1 36.8 2.4 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 OAG18536.1 - 5e-14 52.4 0.9 3.3e-13 49.7 0.0 2.8 3 0 0 3 3 3 1 NUC130/3NT domain DUF5539 PF17693.1 OAG18537.1 - 1.8 8.1 7.1 0.59 9.8 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5539) APH PF01636.23 OAG18538.1 - 8.4e-11 42.2 0.3 1.5e-10 41.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG18538.1 - 0.00062 18.7 0.0 0.00092 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG18538.1 - 0.0057 16.3 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 OAG18538.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.20 OAG18538.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DDE_Tnp_1_5 PF13737.6 OAG18538.1 - 0.14 12.5 0.1 0.41 11.0 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE domain Sec39 PF08314.11 OAG18538.1 - 0.2 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 zf-HIT PF04438.16 OAG18540.1 - 0.055 13.4 3.4 0.088 12.7 3.4 1.3 1 0 0 1 1 1 0 HIT zinc finger MIF PF01187.18 OAG18541.1 - 5.1e-13 49.3 0.1 8.1e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF5386 PF17360.2 OAG18541.1 - 0.87 9.5 5.1 0.63 9.9 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5386) CENP-X PF09415.10 OAG18542.1 - 3.6e-22 78.5 0.1 8.2e-22 77.3 0.0 1.6 2 0 0 2 2 2 1 CENP-S associating Centromere protein X ACP PF06857.11 OAG18542.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Copper-bind PF00127.20 OAG18543.1 - 0.00017 22.0 0.2 0.00033 21.1 0.2 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 OAG18543.1 - 0.0088 16.0 0.5 0.035 14.1 0.5 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain MFS_1 PF07690.16 OAG18544.1 - 6.4e-23 81.3 19.6 1.1e-22 80.4 19.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18544.1 - 1.3e-06 27.5 4.0 2.5e-06 26.6 4.0 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG18544.1 - 0.013 13.9 0.5 0.019 13.4 0.5 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Glt_symporter PF03616.14 OAG18544.1 - 0.15 10.7 0.1 0.26 10.0 0.1 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter HSP70 PF00012.20 OAG18546.1 - 2.2e-11 42.7 0.3 1e-09 37.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OAG18546.1 - 0.034 13.0 0.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein CPSF73-100_C PF11718.8 OAG18551.1 - 1.8e-80 269.6 0.0 3.6e-80 268.6 0.0 1.5 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAG18551.1 - 2.2e-32 111.6 0.0 4.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 OAG18551.1 - 1.2e-18 67.8 0.1 2.4e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OAG18551.1 - 1.1e-16 60.9 0.1 1.9e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OAG18551.1 - 7.8e-12 45.0 0.0 1.7e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 OAG18551.1 - 4.9e-05 23.3 0.4 0.00016 21.6 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG18551.1 - 7.9e-05 22.3 0.8 0.00053 19.6 0.3 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TAF4 PF05236.14 OAG18552.1 - 4.4e-34 118.5 0.0 1.4e-25 90.6 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family OmpH PF03938.14 OAG18554.1 - 0.4 11.0 8.0 6.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 OAG18554.1 - 2.8 8.6 7.3 6.5 7.4 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Mito_carr PF00153.27 OAG18556.1 - 1.1e-42 143.9 8.7 2.6e-16 59.3 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB_2 PF02214.22 OAG18557.1 - 3e-05 24.3 0.0 0.038 14.3 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain Cupin_1 PF00190.22 OAG18558.1 - 3.6e-20 72.1 0.1 5.9e-20 71.4 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG18558.1 - 0.0021 17.8 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Meiotic_rec114 PF03525.14 OAG18558.1 - 0.013 14.5 1.7 0.018 14.0 1.7 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 NDUF_B4 PF07225.12 OAG18559.1 - 0.00015 21.6 0.1 0.00016 21.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.20 OAG18560.1 - 8.7e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG18560.1 - 6.5e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG18560.1 - 8.1e-08 32.6 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG18560.1 - 1.3e-07 31.8 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG18560.1 - 9.7e-07 28.7 0.0 2.7e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG18560.1 - 1.3e-05 25.3 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG18560.1 - 0.0088 16.6 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OGFr_N PF04664.13 OAG18561.1 - 3.7e-18 65.8 0.2 6.7e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DUF1007 PF06226.13 OAG18561.1 - 0.079 12.9 0.4 0.29 11.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1007) Alpha-amylase PF00128.24 OAG18562.1 - 3.7e-24 85.9 3.9 9.8e-24 84.5 3.9 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 OAG18562.1 - 0.0038 17.3 0.2 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) MFS_1 PF07690.16 OAG18563.1 - 1.8e-14 53.5 9.1 3.7e-14 52.4 9.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18563.1 - 1.2e-08 34.2 0.8 1.2e-08 34.2 0.8 2.9 1 1 3 4 4 4 2 Sugar (and other) transporter NTP_transf_6 PF06042.11 OAG18564.1 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Plasmid_RAQPRD PF09686.10 OAG18565.1 - 0.16 12.2 3.7 0.4 10.9 0.3 2.9 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LPP PF04728.13 OAG18565.1 - 0.26 11.7 3.0 9.6 6.7 0.3 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 OAG18565.1 - 1.2 9.4 17.6 0.28 11.5 0.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) ALMT PF11744.8 OAG18565.1 - 8.3 5.1 18.1 1.6 7.5 14.0 1.7 1 1 1 2 2 2 0 Aluminium activated malate transporter Ribosomal_S7 PF00177.21 OAG18566.1 - 1.5e-36 125.3 1.3 1.8e-36 125.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4207 PF13904.6 OAG18567.1 - 0.0059 16.3 11.7 0.0098 15.6 11.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF1501 PF07394.12 OAG18567.1 - 0.27 10.2 5.0 0.39 9.7 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF5437 PF17505.2 OAG18567.1 - 1.5 8.9 4.8 6.3 6.9 4.8 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5437) DUF3280 PF11684.8 OAG18567.1 - 1.7 9.0 12.7 0.31 11.5 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2380) Nucleo_P87 PF07267.11 OAG18567.1 - 2.1 7.1 10.7 2.7 6.8 10.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VIR_N PF15912.5 OAG18567.1 - 7.3 6.1 13.8 12 5.4 13.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal RPE65 PF03055.15 OAG18568.1 - 2.7e-109 366.4 0.4 3.1e-109 366.3 0.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein zf-ANAPC11 PF12861.7 OAG18569.1 - 0.00038 20.5 2.7 0.00068 19.6 2.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG18569.1 - 0.0027 18.0 5.3 0.0058 16.9 5.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG18569.1 - 0.0049 16.6 0.7 0.0049 16.6 0.7 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CorA PF01544.18 OAG18569.1 - 0.026 13.9 1.7 0.036 13.4 1.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3800 PF12686.7 OAG18569.1 - 0.028 15.0 0.1 0.036 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) zinc_ribbon_9 PF14369.6 OAG18569.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon DUF4917 PF16263.5 OAG18569.1 - 0.045 13.1 0.3 0.064 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) zf-RING_2 PF13639.6 OAG18569.1 - 0.063 13.6 10.5 0.43 10.9 10.5 2.1 1 1 0 1 1 1 0 Ring finger domain DUF4687 PF15747.5 OAG18571.1 - 0.35 11.3 7.3 0.36 11.3 5.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) DUF515 PF04415.12 OAG18571.1 - 6.2 5.1 10.6 11 4.2 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.16 OAG18574.1 - 5.1e-32 111.2 29.1 7.2e-32 110.7 29.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG18574.1 - 0.0054 15.1 12.0 0.034 12.4 5.6 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Myticin-prepro PF10690.9 OAG18574.1 - 0.2 11.9 1.8 23 5.3 1.0 2.7 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel TMEM100 PF16311.5 OAG18574.1 - 1 8.9 3.7 4.1 7.0 1.3 2.7 2 0 0 2 2 2 0 Transmembrane protein 100 zf-RING_2 PF13639.6 OAG18575.1 - 3.4e-11 43.3 6.2 6.8e-11 42.3 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG18575.1 - 1.8e-07 31.3 7.7 6.3e-07 29.6 7.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAG18575.1 - 5.5e-07 29.6 2.7 9.5e-07 28.9 2.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG18575.1 - 6.8e-07 29.2 3.6 1.3e-06 28.3 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG18575.1 - 1.4e-06 28.2 6.4 2.3e-06 27.4 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG18575.1 - 2.6e-06 27.2 6.1 4.3e-06 26.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG18575.1 - 1.2e-05 25.1 6.1 2.1e-05 24.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG18575.1 - 2e-05 24.4 3.6 3.6e-05 23.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG18575.1 - 0.0011 18.8 4.8 0.0021 17.9 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OAG18575.1 - 0.0014 18.6 3.4 0.004 17.2 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAG18575.1 - 0.017 14.9 7.8 0.029 14.1 7.8 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 OAG18575.1 - 0.026 14.4 0.9 0.056 13.3 0.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 OAG18575.1 - 0.06 13.5 0.9 0.13 12.4 0.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 OAG18575.1 - 0.063 12.9 5.2 0.12 12.0 5.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OAG18575.1 - 0.078 12.8 2.5 0.15 11.9 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OAG18575.1 - 0.33 11.1 3.2 0.99 9.6 3.2 1.9 1 1 0 1 1 1 0 RING-variant domain Isochorismatase PF00857.20 OAG18577.1 - 2.4e-41 141.8 0.1 2.7e-41 141.7 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_11 PF00457.17 OAG18579.1 - 3.4e-78 261.3 24.0 4.1e-78 261.1 24.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ALO PF04030.14 OAG18580.1 - 1.8e-85 286.9 1.6 2.7e-85 286.3 1.6 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAG18580.1 - 3.1e-33 114.5 0.1 4.6e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cupin_3 PF05899.12 OAG18581.1 - 4.4e-05 23.1 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 OAG18581.1 - 0.0007 19.4 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ DUF4437 PF14499.6 OAG18581.1 - 0.041 13.0 0.0 0.07 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4437) Hexapep PF00132.24 OAG18583.1 - 2.3e-05 23.9 0.3 0.35 10.7 0.1 3.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG18583.1 - 4.7e-05 23.8 0.0 9e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OAG18583.1 - 0.022 12.9 0.0 0.033 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 OAG18583.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.12 OAG18583.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase PARP PF00644.20 OAG18585.1 - 6.5e-59 198.8 0.0 1.3e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OAG18585.1 - 8.5e-43 145.7 0.7 1.4e-42 145.0 0.7 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OAG18585.1 - 7.6e-23 80.4 1.5 1.5e-22 79.4 1.5 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 OAG18585.1 - 2.7e-10 40.5 0.0 1.8e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG18585.1 - 3.4e-06 26.9 0.0 9.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OAG18585.1 - 0.026 14.9 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG18585.1 - 0.052 13.8 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Herpes_UL25 PF01499.16 OAG18585.1 - 0.29 9.6 1.6 2.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family F-box-like PF12937.7 OAG18586.1 - 0.0028 17.5 0.1 0.0064 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG18586.1 - 0.014 15.3 0.1 0.057 13.3 0.1 2.1 2 0 0 2 2 2 0 F-box domain RNA_pol_3_Rpc31 PF11705.8 OAG18586.1 - 0.029 14.6 7.3 0.044 14.0 7.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_M24 PF00557.24 OAG18587.1 - 3.3e-60 203.4 0.0 4.6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG18587.1 - 6.2e-25 87.3 0.0 1.1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain MFS_1 PF07690.16 OAG18588.1 - 2.1e-36 125.6 30.4 2.6e-36 125.3 27.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18588.1 - 3e-11 42.9 17.0 4.1e-11 42.4 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4519 PF15012.6 OAG18588.1 - 0.1 12.8 2.3 0.97 9.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Trp_oprn_chp PF09534.10 OAG18588.1 - 1.7 8.4 9.5 0.8 9.5 3.7 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CN_hydrolase PF00795.22 OAG18591.1 - 3.6e-37 128.1 0.0 5e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase RelE PF06296.12 OAG18591.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system Gene66 PF02053.15 OAG18591.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Gene 66 (IR5) protein FBPase PF00316.20 OAG18592.1 - 1.7e-20 73.3 0.0 2.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Thyroglobulin_1 PF00086.18 OAG18594.1 - 0.013 15.2 3.1 0.024 14.3 3.1 1.4 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Beta-lactamase PF00144.24 OAG18595.1 - 5.6e-31 108.0 0.1 9.1e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase PHD PF00628.29 OAG18596.1 - 6.1e-08 32.4 5.7 1e-07 31.7 5.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 OAG18596.1 - 0.016 15.1 1.3 0.031 14.2 1.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG18596.1 - 0.21 11.2 3.5 0.35 10.5 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 OAG18596.1 - 0.48 10.5 2.8 1.1 9.3 2.8 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_3 PF13922.6 OAG18596.1 - 4.6 7.7 8.6 1.2 9.6 3.1 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Herpes_gE PF02480.16 OAG18597.1 - 0.00014 20.7 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.6 OAG18597.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OAG18597.1 - 0.029 14.3 0.2 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family SKG6 PF08693.10 OAG18597.1 - 0.061 12.8 1.3 0.12 11.8 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG18597.1 - 0.091 13.6 0.0 0.16 12.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PgaD PF13994.6 OAG18597.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein SDF PF00375.18 OAG18597.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family AIM3 PF17096.5 OAG18598.1 - 3.4e-05 24.7 1.4 3.4e-05 24.7 1.4 5.8 4 3 1 6 6 6 1 Altered inheritance of mitochondria protein 3 ELO PF01151.18 OAG18599.1 - 1e-86 290.5 8.0 1.3e-86 290.2 8.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PMSI1 PF15322.6 OAG18599.1 - 4 6.8 7.9 5.6 6.3 6.2 1.9 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative ANAPC10 PF03256.16 OAG18600.1 - 3.2e-43 147.5 0.0 3.5e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TruD PF01142.18 OAG18602.1 - 1.4e-44 152.6 1.3 5.1e-20 71.7 0.0 4.8 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) MAT1 PF06391.13 OAG18602.1 - 8.5 6.1 17.6 2.2 8.1 8.8 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Pectate_lyase_3 PF12708.7 OAG18603.1 - 5.9e-94 313.9 10.3 4.4e-83 278.4 5.9 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG18603.1 - 1.4e-05 24.7 2.3 0.047 13.4 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 OAG18604.1 - 4e-15 55.8 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG18604.1 - 0.072 11.9 0.0 0.56 8.9 0.0 2.2 3 0 0 3 3 3 0 Alanine-glyoxylate amino-transferase Mtc PF03820.17 OAG18606.1 - 8.8e-122 406.0 0.0 9.9e-122 405.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier HSP70 PF00012.20 OAG18607.1 - 2.4e-60 204.4 2.8 2.5e-56 191.1 0.2 4.0 2 1 1 4 4 4 2 Hsp70 protein SR-25 PF10500.9 OAG18607.1 - 0.0066 16.1 11.9 0.0066 16.1 11.9 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 OAG18607.1 - 0.08 13.3 17.6 0.39 11.0 6.1 3.8 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF1117 PF06547.12 OAG18607.1 - 3.2 8.3 10.1 0.36 11.4 1.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1117) SIP PF04954.13 OAG18607.1 - 7.3 7.1 8.2 12 6.5 0.7 3.7 4 1 0 5 5 5 0 Siderophore-interacting protein KNOX2 PF03791.13 OAG18608.1 - 0.33 10.5 12.2 5.1 6.7 0.5 3.5 3 0 0 3 3 3 0 KNOX2 domain Exonuc_VII_L PF02601.15 OAG18608.1 - 0.75 9.3 12.0 1.3 8.5 12.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 OAG18608.1 - 6.4 5.6 6.5 9 5.1 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 OAG18608.1 - 8.1 5.2 13.8 14 4.3 13.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_C12 PF01088.21 OAG18610.1 - 6.4e-66 222.1 0.0 8.7e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OAG18610.1 - 7.4e-13 48.2 0.1 1.9e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Sulfatase PF00884.23 OAG18611.1 - 1.8e-56 191.8 0.3 2.4e-56 191.4 0.3 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG18611.1 - 0.00039 20.6 0.1 0.00083 19.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Zn_clus PF00172.18 OAG18612.1 - 2.2e-08 34.1 11.8 3.5e-08 33.4 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG18612.1 - 1.5e-07 30.6 1.4 2.5e-07 29.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCDC92 PF14916.6 OAG18612.1 - 0.11 12.3 0.2 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function HEAT_EZ PF13513.6 OAG18613.1 - 3.7e-31 107.2 14.0 7.1e-14 52.0 0.0 10.1 8 2 2 10 10 10 6 HEAT-like repeat HEAT PF02985.22 OAG18613.1 - 3.7e-23 79.6 12.9 0.0021 18.1 0.0 10.6 12 0 0 12 12 10 6 HEAT repeat HEAT_2 PF13646.6 OAG18613.1 - 5.1e-19 68.5 0.8 0.0018 18.6 0.0 7.0 5 1 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 OAG18613.1 - 8.1e-11 42.2 0.4 0.02 14.9 0.0 5.1 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG18613.1 - 2e-10 41.1 0.4 0.081 13.5 0.0 6.6 6 2 1 7 7 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 OAG18613.1 - 1.8e-08 34.1 3.1 2.8 8.1 0.0 6.8 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 OAG18613.1 - 5.3e-08 32.4 5.8 0.081 12.0 0.1 5.2 6 1 0 6 6 6 3 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OAG18613.1 - 5.9e-08 32.5 0.0 3.4e-05 23.7 0.0 3.9 2 1 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OAG18613.1 - 1.1e-05 25.6 0.2 0.00031 20.9 0.0 3.5 5 0 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAG18613.1 - 1.6e-05 24.6 0.3 5.6 6.5 0.0 6.2 5 3 1 6 6 6 1 CLASP N terminal DRIM PF07539.12 OAG18613.1 - 0.00088 17.7 0.1 1.4 7.2 0.0 3.6 3 1 0 3 3 3 2 Down-regulated in metastasis Tti2 PF10521.9 OAG18613.1 - 0.0009 18.9 0.1 2.2 7.7 0.0 3.3 3 0 0 3 3 2 2 Tti2 family RIX1 PF08167.12 OAG18613.1 - 0.0025 17.6 0.2 2.2 8.0 0.0 4.0 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 OAG18613.1 - 0.0036 17.6 0.0 5.8 7.3 0.0 4.4 4 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain DUF3437 PF11919.8 OAG18613.1 - 0.011 15.7 0.1 3.4 7.7 0.0 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF3437) Xpo1 PF08389.12 OAG18613.1 - 0.038 14.1 0.0 1.9 8.5 0.0 3.1 2 1 0 2 2 1 0 Exportin 1-like protein BRCC36_C PF18110.1 OAG18613.1 - 0.039 14.1 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain HEAT_PBS PF03130.16 OAG18613.1 - 0.049 14.3 1.3 84 4.3 0.0 4.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF4003 PF13170.6 OAG18613.1 - 0.11 11.8 0.6 9 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) DUF4303 PF14136.6 OAG18613.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Gcn1_N PF12074.8 OAG18613.1 - 0.16 11.2 0.2 20 4.4 0.0 3.5 4 0 0 4 4 4 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal BDHCT_assoc PF16204.5 OAG18613.1 - 0.35 10.5 2.1 0.6 9.7 2.1 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein HET PF06985.11 OAG18615.1 - 3.3e-16 59.9 0.3 3.8e-16 59.7 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPRY PF00622.28 OAG18617.1 - 6.1e-20 71.5 0.1 9.7e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain MFS_1 PF07690.16 OAG18618.1 - 4.2e-28 98.3 41.5 1.2e-27 96.8 42.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG18618.1 - 2.1 7.5 28.9 2.7e+02 0.6 28.8 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF872 PF05915.12 OAG18619.1 - 0.033 14.4 1.2 0.081 13.1 1.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CRPA PF05745.11 OAG18619.1 - 7 6.7 7.2 1.2 9.2 3.0 1.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tyrosinase PF00264.20 OAG18621.1 - 1.6e-49 169.2 0.2 2.4e-49 168.6 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_excise PF03013.14 OAG18621.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Exo_endo_phos PF03372.23 OAG18623.1 - 0.00025 20.6 1.3 0.00053 19.6 1.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TetR_C_28 PF17937.1 OAG18623.1 - 0.11 12.9 0.5 8.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain XRCC4 PF06632.12 OAG18624.1 - 0.65 8.8 4.9 1.5 7.6 4.9 1.6 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DTHCT PF08070.11 OAG18624.1 - 7.6 7.3 23.5 10 6.9 10.0 2.9 2 1 0 2 2 2 0 DTHCT (NUC029) region PP2C PF00481.21 OAG18626.1 - 2.5e-35 122.4 0.0 2.1e-29 102.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG18626.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C HEAT PF02985.22 OAG18627.1 - 4.3e-13 48.3 10.5 0.00011 22.2 0.0 9.1 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 OAG18627.1 - 1.1e-12 48.1 13.6 4.9e-08 33.3 0.0 8.2 6 2 2 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 OAG18627.1 - 1.1e-08 35.3 10.3 0.011 16.1 0.0 7.6 4 2 3 7 7 7 3 HEAT repeats IBN_N PF03810.19 OAG18627.1 - 3.1e-08 33.4 6.0 6.5e-07 29.2 1.8 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 OAG18627.1 - 1.4e-07 31.3 0.1 0.035 13.7 0.0 4.6 3 1 2 5 5 5 2 CLASP N terminal DUF3385 PF11865.8 OAG18627.1 - 8.4e-05 22.5 2.5 0.19 11.6 0.7 4.5 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 OAG18627.1 - 0.00036 20.3 0.1 1.4 8.6 0.1 4.0 1 1 2 3 3 3 1 rRNA processing/ribosome biogenesis Arm PF00514.23 OAG18627.1 - 0.00069 19.6 6.4 0.58 10.3 0.0 6.0 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 OAG18627.1 - 0.018 15.0 0.5 1.1 9.1 0.0 2.9 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4487 PF14868.6 OAG18627.1 - 0.022 13.6 0.2 0.084 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) CLIP PF12032.8 OAG18627.1 - 0.11 12.9 0.0 31 5.0 0.0 2.9 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases HEAT_PBS PF03130.16 OAG18627.1 - 0.13 13.0 4.1 25 5.9 0.1 5.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3338 PF11819.8 OAG18627.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) CMV_US PF08001.11 OAG18629.1 - 0.09 12.0 0.3 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 CMV US RRM_1 PF00076.22 OAG18630.1 - 7.6e-46 153.8 1.2 1.5e-20 72.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAG18630.1 - 2.3e-14 54.2 0.1 5.9e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAG18630.1 - 4.6e-08 32.8 0.0 0.054 13.4 0.0 3.6 3 1 0 3 3 3 3 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OAG18630.1 - 0.0069 16.6 0.0 0.34 11.1 0.0 3.0 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAG18630.1 - 0.063 12.9 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 OAG18631.1 - 3.1e-19 68.9 0.7 9.4e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAG18631.1 - 9.8e-13 48.6 19.7 1.1e-12 48.4 18.8 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 OAG18631.1 - 0.0068 16.6 0.2 0.031 14.5 0.1 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region COX14 PF14880.6 OAG18631.1 - 0.02 14.7 0.5 0.06 13.2 0.5 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Thaumatin PF00314.17 OAG18632.1 - 1.6e-69 233.8 4.6 2.2e-69 233.3 4.6 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 OAG18632.1 - 0.00073 18.9 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Beta-1,3-glucanase Mannosidase_ig PF17786.1 OAG18633.1 - 1.3e-19 70.6 0.2 4e-19 69.0 0.2 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAG18633.1 - 2.9e-11 44.0 1.1 1.2e-10 42.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 OAG18633.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.18 OAG18635.1 - 2.9e-23 82.2 0.4 5.6e-23 81.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18635.1 - 1.9e-07 31.1 8.7 3.4e-07 30.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_efflux PF01545.21 OAG18636.1 - 1.3e-18 67.5 7.1 1.7e-18 67.1 7.1 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG18636.1 - 5.7e-11 42.4 0.7 1.5e-10 41.0 0.7 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CxC6 PF18721.1 OAG18638.1 - 0.17 12.2 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Acetyltransf_1 PF00583.25 OAG18639.1 - 1.2e-08 35.2 0.0 3.3e-08 33.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG18639.1 - 3.7e-07 30.5 0.0 3e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG18639.1 - 2.7e-06 27.3 0.0 0.00049 20.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG18639.1 - 0.0026 17.8 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG18639.1 - 0.03 14.4 0.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Molybdopterin_N PF18364.1 OAG18639.1 - 0.14 12.2 0.7 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain p450 PF00067.22 OAG18640.1 - 9.1e-57 192.8 0.0 1.5e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAG18642.1 - 2e-06 27.8 8.7 2e-06 27.8 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dus PF01207.17 OAG18643.1 - 6.5e-58 196.2 0.0 2.5e-57 194.4 0.0 2.0 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OAG18643.1 - 0.0049 16.1 0.0 0.016 14.4 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ComA PF02679.15 OAG18643.1 - 0.014 14.9 0.2 0.034 13.6 0.0 1.7 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) BKACE PF05853.12 OAG18643.1 - 0.048 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme FYVE PF01363.21 OAG18645.1 - 1.5e-13 50.6 12.7 2.4e-13 50.0 12.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 OAG18645.1 - 0.0039 17.4 3.9 0.0039 17.4 3.9 1.9 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 OAG18645.1 - 0.28 11.4 12.1 0.062 13.5 7.0 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger GMC_oxred_N PF00732.19 OAG18646.1 - 3e-46 158.2 0.2 1e-45 156.4 0.2 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG18646.1 - 4.4e-27 95.4 0.9 8e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG18646.1 - 6.1e-06 25.6 1.0 0.00011 21.4 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG18646.1 - 3.3e-05 23.3 0.1 0.00021 20.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG18646.1 - 7e-05 22.2 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG18646.1 - 0.00034 19.9 0.1 0.01 15.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAG18646.1 - 0.0005 20.3 0.3 0.0013 18.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG18646.1 - 0.00073 19.2 1.1 0.048 13.2 0.3 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG18646.1 - 0.015 14.7 0.4 0.024 14.0 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG18646.1 - 0.045 12.4 0.2 0.078 11.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG18646.1 - 0.063 12.5 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 OAG18647.1 - 4.2e-15 56.0 0.1 5.3e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG18647.1 - 4.9e-08 33.1 0.2 9.4e-08 32.2 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG18647.1 - 7.1e-06 26.0 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG18647.1 - 0.00018 21.1 0.0 0.0079 15.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG18647.1 - 0.0007 19.1 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 OAG18647.1 - 0.071 13.2 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAG18647.1 - 0.091 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AhpC-TSA PF00578.21 OAG18647.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family ECH_1 PF00378.20 OAG18648.1 - 8.4e-27 94.1 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG18648.1 - 1.7e-08 34.3 0.0 9e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Epimerase PF01370.21 OAG18649.1 - 2.6e-15 56.6 0.0 3.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG18649.1 - 1.9e-09 36.9 0.0 2.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG18649.1 - 1.1e-07 31.3 0.1 0.00097 18.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG18649.1 - 0.00051 19.6 0.2 0.0014 18.1 0.2 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG18649.1 - 0.00066 19.6 0.9 0.0025 17.7 0.8 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG18649.1 - 0.0047 16.5 0.2 0.52 9.8 0.0 2.7 3 0 0 3 3 3 1 NmrA-like family Acetyltransf_10 PF13673.7 OAG18650.1 - 0.00026 20.9 0.0 0.26 11.2 0.0 2.8 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG18650.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG18650.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 OAG18650.1 - 0.042 14.6 0.0 0.2 12.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAF-AH_p_II PF03403.13 OAG18651.1 - 6.5e-08 31.5 0.0 8.2e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 OAG18651.1 - 0.042 13.6 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0444 PF15475.6 OAG18651.1 - 0.047 13.9 0.7 0.13 12.6 0.7 1.7 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 FtsK_4TM PF13491.6 OAG18651.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Oxidored_molyb PF00174.19 OAG18652.1 - 1.5e-53 180.9 0.0 2.6e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG18652.1 - 2.2e-37 128.2 0.2 5.4e-37 126.9 0.2 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 OAG18652.1 - 2.6e-23 82.8 0.6 2.7e-22 79.5 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG18652.1 - 7.5e-20 71.1 0.0 1e-08 35.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 OAG18652.1 - 2.2e-14 53.4 0.2 5.3e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG18652.1 - 0.0043 17.2 0.2 4.5 7.4 0.0 2.8 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MCM_bind PF09739.9 OAG18652.1 - 1.6 7.1 7.9 2.7 6.3 7.9 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MoaC PF01967.21 OAG18653.1 - 7.4e-47 158.8 0.0 1.3e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mei5 PF10376.9 OAG18653.1 - 0.053 13.4 7.0 0.12 12.3 7.0 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF4570 PF15134.6 OAG18653.1 - 0.19 11.8 9.3 0.15 12.1 6.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) V_ATPase_I PF01496.19 OAG18653.1 - 1 7.2 6.6 1.5 6.6 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mob_synth_C PF06463.13 OAG18654.1 - 2.1e-35 121.5 0.0 1.9e-34 118.4 0.0 2.1 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAG18654.1 - 1.7e-26 93.6 0.0 3.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG18654.1 - 0.0001 22.6 0.0 0.0003 21.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Enolase_N PF03952.16 OAG18654.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain His_Phos_2 PF00328.22 OAG18656.1 - 7.6e-66 223.0 0.0 9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AA_permease_2 PF13520.6 OAG18657.1 - 9.7e-58 196.0 52.3 1.2e-57 195.7 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG18657.1 - 2.7e-13 49.4 44.2 4.4e-13 48.6 44.2 1.3 1 0 0 1 1 1 1 Amino acid permease GAGA PF09237.11 OAG18658.1 - 0.1 12.4 0.6 0.28 11.0 0.6 1.7 1 0 0 1 1 1 0 GAGA factor p450 PF00067.22 OAG18659.1 - 2.4e-70 237.6 0.0 3e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 OAG18661.1 - 0.015 15.2 0.1 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAG18661.1 - 0.073 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain Abhydrolase_1 PF00561.20 OAG18662.1 - 4.7e-18 65.8 0.1 6.1e-17 62.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG18662.1 - 1.6e-11 44.0 0.0 2.7e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG18662.1 - 2.1e-07 31.8 0.0 4.9e-07 30.6 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 OAG18662.1 - 5.4e-05 22.8 0.2 0.12 12.0 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OAG18662.1 - 0.016 15.1 0.3 0.14 12.0 0.3 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OAG18662.1 - 0.058 13.0 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAG18662.1 - 0.073 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 OAG18662.1 - 0.094 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S15 PF02129.18 OAG18662.1 - 0.16 11.6 0.0 0.48 10.0 0.0 1.9 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Aldo_ket_red PF00248.21 OAG18663.1 - 5.7e-52 176.7 0.0 6.5e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyoxalase PF00903.25 OAG18663.1 - 0.097 12.9 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hyd_65N_2 PF14498.6 OAG18665.1 - 8.7e-54 182.9 0.0 1.5e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 OAG18665.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-Mss51 PF13824.6 OAG18666.1 - 1.3e-28 98.8 8.2 3.2e-28 97.6 8.2 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DTW PF03942.15 OAG18666.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 DTW domain zf-MYND PF01753.18 OAG18666.1 - 0.25 11.5 6.6 0.047 13.8 2.6 1.8 2 0 0 2 2 2 0 MYND finger DNA_pol_A_exo1 PF01612.20 OAG18667.1 - 1.6e-09 37.7 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease NmrA PF05368.13 OAG18671.1 - 3.6e-45 154.3 0.0 3.4e-43 147.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 OAG18671.1 - 4.8e-39 133.8 0.5 1.5e-35 122.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18671.1 - 9.9e-27 94.0 0.1 2.1e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG18671.1 - 1.1e-16 61.2 0.2 1.1e-14 54.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG18671.1 - 6.9e-09 35.5 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG18671.1 - 4.4e-08 33.3 0.1 8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 OAG18671.1 - 0.00017 21.1 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 OAG18671.1 - 0.00056 20.1 0.0 0.0016 18.7 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.24 OAG18671.1 - 0.017 15.6 0.2 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG18671.1 - 0.051 12.6 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG18671.1 - 0.12 11.4 0.1 3 6.9 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain PALP PF00291.25 OAG18672.1 - 2.9e-62 210.7 0.4 3.3e-62 210.6 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF108 PF01958.18 OAG18672.1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF108 Lig_chan PF00060.26 OAG18673.1 - 0.097 12.5 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel Amidohydro_2 PF04909.14 OAG18674.1 - 2.9e-24 86.4 0.1 3.7e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidase PF01425.21 OAG18677.1 - 1.9e-108 363.3 0.0 3.4e-108 362.5 0.0 1.4 1 1 0 1 1 1 1 Amidase DUF4996 PF16387.5 OAG18677.1 - 0.086 13.3 0.1 0.89 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Ysc84 PF04366.12 OAG18678.1 - 2.1e-42 143.9 0.1 3.8e-42 143.0 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 OAG18678.1 - 3.9e-14 52.0 0.3 1e-13 50.7 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAG18678.1 - 2.1e-13 49.7 0.2 6.4e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAG18678.1 - 2.3e-08 33.8 0.0 4.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 OAG18679.1 - 1.1e-27 97.0 60.8 6.2e-26 91.2 52.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily A_deaminase PF00962.22 OAG18680.1 - 1.1e-46 159.7 0.0 3.1e-46 158.2 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Asparaginase_2 PF01112.18 OAG18682.1 - 5.9e-60 202.9 0.0 1.6e-52 178.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase HET PF06985.11 OAG18683.1 - 7.7e-14 52.3 4.6 6.8e-11 42.7 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FMO-like PF00743.19 OAG18684.1 - 6.5e-15 54.5 0.3 9.4e-12 44.1 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG18684.1 - 7e-10 39.0 0.0 3.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG18684.1 - 2.2e-09 36.9 0.0 6.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG18684.1 - 5.4e-05 22.5 0.3 0.011 14.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG18684.1 - 0.00018 20.8 0.7 0.02 14.1 0.2 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG18684.1 - 0.00031 20.4 0.0 0.2 11.2 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG18684.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAG18684.1 - 0.067 13.2 0.0 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG18684.1 - 0.14 12.2 0.0 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ParA PF10609.9 OAG18685.1 - 1.3e-91 306.4 0.0 1.5e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG18685.1 - 2.3e-12 47.1 0.0 9.4e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAG18685.1 - 5.9e-11 42.6 0.1 2e-08 34.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 OAG18685.1 - 4.7e-06 26.1 0.0 7.4e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OAG18685.1 - 0.00017 20.9 0.6 0.0037 16.5 0.3 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OAG18685.1 - 0.00017 21.5 0.2 0.087 12.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG18685.1 - 0.0011 18.5 0.0 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 OAG18685.1 - 0.0017 17.9 0.0 0.35 10.3 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 OAG18685.1 - 0.063 12.2 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 OAG18685.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CBP_BcsQ PF06564.12 OAG18685.1 - 0.094 12.2 0.2 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TRAUB PF08164.12 OAG18686.1 - 1.8e-29 102.1 0.8 9.1e-29 99.8 0.1 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OAG18686.1 - 1.2e-27 97.3 2.9 1.2e-27 97.3 2.9 2.4 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor p450 PF00067.22 OAG18687.1 - 1.8e-60 205.0 0.0 2.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_6 PF00970.24 OAG18688.1 - 1.6e-32 111.8 0.0 2.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG18688.1 - 8.8e-31 106.8 0.0 5.7e-30 104.2 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAG18688.1 - 1.4e-19 69.9 0.0 2.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG18688.1 - 3.7e-05 23.9 0.0 0.00069 19.8 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG18688.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3231 PF11553.8 OAG18688.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) 3HCDH_N PF02737.18 OAG18689.1 - 6.4e-29 101.1 0.0 1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG18689.1 - 5e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 OAG18689.1 - 1.5e-06 27.9 0.1 0.00075 19.1 0.0 3.1 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NAD_binding_2 PF03446.15 OAG18689.1 - 7.3e-05 23.0 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG18689.1 - 0.00038 20.5 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NHL PF01436.21 OAG18689.1 - 0.003 17.5 1.1 13 6.1 0.0 4.6 5 0 0 5 5 4 1 NHL repeat Ldl_recept_b PF00058.17 OAG18689.1 - 0.0052 17.2 4.2 0.17 12.4 0.0 4.5 5 1 0 5 5 4 1 Low-density lipoprotein receptor repeat class B F420_oxidored PF03807.17 OAG18689.1 - 0.0056 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG18689.1 - 0.0098 15.3 0.0 0.023 14.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arylesterase PF01731.20 OAG18689.1 - 0.02 15.1 0.0 4.2 7.6 0.0 3.4 3 0 0 3 3 3 0 Arylesterase Pyr_redox PF00070.27 OAG18689.1 - 0.028 15.0 0.0 0.26 11.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG18689.1 - 0.049 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.14 OAG18689.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG18689.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 OAG18691.1 - 9.4e-06 25.3 0.2 0.00066 19.3 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family Semialdhyde_dh PF01118.24 OAG18691.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GST_N_3 PF13417.6 OAG18692.1 - 3.9e-12 46.4 0.0 1.9e-10 41.0 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG18692.1 - 1.6e-11 44.2 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG18692.1 - 3.7e-10 40.0 0.0 1.6e-09 37.9 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG18692.1 - 1.1e-08 35.2 0.0 1.7e-06 28.2 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG18692.1 - 9.3e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG18692.1 - 0.0013 18.9 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 OAG18693.1 - 3.2e-44 151.6 0.0 3.9e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RecX PF02631.16 OAG18693.1 - 0.056 13.9 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 RecX family Zn_clus PF00172.18 OAG18694.1 - 1.2e-08 34.9 6.7 2.7e-08 33.8 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG18694.1 - 7.3e-06 26.2 17.3 0.00051 20.3 0.6 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 OAG18694.1 - 3.9e-05 22.8 5.4 7.7e-05 21.9 3.4 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG18694.1 - 3.9e-05 23.9 15.4 7.9e-05 22.9 5.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 OAG18694.1 - 0.00081 19.6 4.1 0.0037 17.5 3.7 2.3 2 0 0 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 OAG18694.1 - 0.00089 19.8 4.9 0.055 14.1 1.2 3.1 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-Di19 PF05605.12 OAG18694.1 - 0.0073 16.6 1.8 0.0073 16.6 1.8 2.4 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OAG18694.1 - 0.017 15.9 0.4 0.017 15.9 0.4 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OAG18694.1 - 0.019 14.6 1.0 0.36 10.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain PyrI_C PF02748.15 OAG18694.1 - 0.029 14.2 2.8 0.12 12.3 0.4 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FAD_binding_3 PF01494.19 OAG18695.1 - 9.9e-05 21.7 0.1 0.057 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG18695.1 - 0.0071 15.6 0.1 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG18695.1 - 0.019 14.6 0.7 3.4 7.1 0.0 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG18695.1 - 0.039 13.1 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG18695.1 - 0.097 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_3 PF07859.13 OAG18696.1 - 7.9e-42 143.5 0.0 4.4e-32 111.6 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG18696.1 - 3.3e-16 59.1 0.0 2.1e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAG18696.1 - 0.012 14.9 0.0 0.052 12.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 OAG18696.1 - 0.013 14.4 0.1 0.063 12.1 0.1 1.8 1 1 0 1 1 1 0 Carboxylesterase family DUF3089 PF11288.8 OAG18696.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) adh_short PF00106.25 OAG18697.1 - 1.4e-30 106.2 0.0 2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18697.1 - 4.1e-23 82.1 0.0 5.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18697.1 - 0.00092 19.2 0.6 0.0071 16.3 0.6 2.3 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAG18697.1 - 0.016 15.5 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 OAG18697.1 - 0.1 12.5 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG18697.1 - 0.11 12.0 0.1 0.31 10.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF572 PF04502.13 OAG18698.1 - 1e-71 242.3 0.0 1.3e-71 241.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) GTP_EFTU PF00009.27 OAG18699.1 - 1.8e-41 141.9 0.0 3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG18699.1 - 7.6e-30 103.5 0.1 2e-29 102.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG18699.1 - 3.6e-06 27.3 0.1 1.2e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG18699.1 - 0.0019 18.3 0.1 0.012 15.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Trnau1ap PF17654.1 OAG18699.1 - 9.6 7.1 19.3 25 5.8 19.3 1.7 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Ran-binding PF05508.11 OAG18700.1 - 3.2e-124 414.0 0.1 4.1e-124 413.6 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.17 OAG18701.1 - 1.6e-18 66.5 0.7 3.2e-18 65.5 0.7 1.6 1 0 0 1 1 1 1 BSD domain BSP_II PF05432.11 OAG18701.1 - 4.7e-05 23.2 22.1 4.7e-05 23.2 22.1 2.3 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 OAG18701.1 - 0.0018 16.4 21.5 0.0018 16.4 21.5 2.6 2 1 1 3 3 3 1 DNA polymerase phi ApoA-II PF04711.13 OAG18701.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) WGG PF10273.9 OAG18702.1 - 4.4e-28 97.8 1.3 7.8e-28 97.0 1.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Cupin_5 PF06172.11 OAG18703.1 - 1.2e-48 164.9 0.0 1.4e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Zn_clus PF00172.18 OAG18705.1 - 1e-07 31.9 11.2 1e-07 31.9 11.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 OAG18706.1 - 3e-49 168.1 0.1 2e-48 165.4 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase Pyr_redox_2 PF07992.14 OAG18708.1 - 2.6e-14 53.1 0.0 3.2e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG18708.1 - 5.5e-12 44.9 2.1 1.4e-10 40.3 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG18708.1 - 2.4e-09 37.3 0.2 3.1e-08 33.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG18708.1 - 5e-09 35.7 0.0 4.8e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG18708.1 - 2.4e-07 30.3 0.0 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG18708.1 - 1.2e-05 25.1 1.3 0.0075 15.9 0.1 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG18708.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG18708.1 - 0.007 15.5 1.2 1.4 7.9 0.1 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAG18708.1 - 0.056 12.7 0.4 4.3 6.5 0.0 3.2 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG18708.1 - 0.061 12.0 1.2 0.31 9.7 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 OAG18708.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG18708.1 - 0.29 10.3 1.1 0.51 9.5 0.0 1.9 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 OAG18708.1 - 0.51 10.3 6.4 8.9 6.3 0.0 3.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding Gly_transf_sug PF04488.15 OAG18709.1 - 4.7e-09 36.8 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG18709.1 - 0.039 13.3 0.3 0.067 12.5 0.3 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OAG18709.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Abhydrolase_3 PF07859.13 OAG18710.1 - 2.6e-09 37.3 0.0 6.5e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold VHS PF00790.19 OAG18712.1 - 2.3e-42 144.2 0.1 2.3e-42 144.2 0.1 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAG18712.1 - 1.5e-17 63.4 3.4 2.9e-17 62.6 3.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 OAG18712.1 - 2.6e-05 24.4 0.0 8.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 OAG18712.1 - 0.00013 21.6 21.4 0.0084 16.0 1.9 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 OAG18712.1 - 0.00093 19.4 0.6 0.0018 18.5 0.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Npa1 PF11707.8 OAG18712.1 - 0.08 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal UCH PF00443.29 OAG18713.1 - 3.3e-53 180.8 0.0 1.1e-52 179.2 0.0 1.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG18713.1 - 2.3e-15 57.0 0.0 4.9e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 OAG18713.1 - 6.8e-05 23.0 0.3 0.0036 17.5 0.1 2.5 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.20 OAG18713.1 - 0.021 15.4 0.0 0.065 13.8 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain Rubredoxin_2 PF18073.1 OAG18713.1 - 3.2 7.6 4.6 9.7 6.0 0.5 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Arginosuc_synth PF00764.19 OAG18714.1 - 5.2e-152 506.6 0.0 5.9e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAG18714.1 - 0.0036 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF3106 PF11304.8 OAG18715.1 - 0.0027 18.1 0.4 0.007 16.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) PARM PF17061.5 OAG18718.1 - 0.13 12.3 3.6 0.17 12.0 3.6 1.1 1 0 0 1 1 1 0 PARM Pyocin_S PF06958.12 OAG18718.1 - 0.41 11.2 3.0 0.69 10.5 3.0 1.4 1 0 0 1 1 1 0 S-type Pyocin Epimerase PF01370.21 OAG18719.1 - 7.3e-06 25.6 0.0 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG18719.1 - 0.00078 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NuA4 PF09340.10 OAG18720.1 - 0.00076 19.3 0.3 0.0024 17.7 0.0 2.0 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF2383 PF09537.10 OAG18720.1 - 0.06 13.7 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DZR PF12773.7 OAG18722.1 - 0.033 14.2 0.3 0.074 13.1 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Muted PF14942.6 OAG18722.1 - 4.4 7.6 8.9 0.32 11.4 2.3 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ABC_tran PF00005.27 OAG18723.1 - 1.8e-42 145.1 0.1 1.4e-21 77.5 0.0 3.5 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OAG18723.1 - 1.5e-15 57.8 9.7 7.9e-09 35.7 0.2 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG18723.1 - 4.8e-12 45.8 0.5 0.041 13.3 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG18723.1 - 2e-07 30.7 0.7 0.00041 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 OAG18723.1 - 3.6e-07 30.1 6.3 3.6e-07 30.1 6.3 1.8 2 0 0 2 2 1 1 ABC transporter AAA_30 PF13604.6 OAG18723.1 - 7.3e-05 22.6 1.6 0.045 13.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OAG18723.1 - 0.00016 21.5 2.6 0.014 15.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG18723.1 - 0.00076 19.8 0.2 0.65 10.3 0.0 3.2 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 OAG18723.1 - 0.0014 18.6 3.2 1.3 9.0 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA PF00004.29 OAG18723.1 - 0.0017 18.8 0.9 0.62 10.5 0.2 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAG18723.1 - 0.0085 15.3 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 OAG18723.1 - 0.01 15.9 0.0 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OAG18723.1 - 0.011 15.3 0.3 6.7 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG18723.1 - 0.018 15.2 3.2 2.9 8.0 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OAG18723.1 - 0.023 14.2 0.2 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAG18723.1 - 0.032 14.8 0.9 5.5 7.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 OAG18723.1 - 0.042 13.3 0.2 6.9 6.1 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 OAG18723.1 - 0.045 14.1 1.9 3.1 8.2 0.4 2.8 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG18723.1 - 0.051 13.5 6.8 0.27 11.1 0.0 3.2 4 0 0 4 4 3 0 RsgA GTPase AAA_19 PF13245.6 OAG18723.1 - 0.075 13.4 1.8 0.25 11.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAG18723.1 - 0.14 11.7 1.3 15 5.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OAG18723.1 - 0.15 12.0 1.8 13 5.6 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.14 OAG18723.1 - 0.16 12.0 4.0 0.35 10.9 0.0 3.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG18723.1 - 0.18 12.2 0.5 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 OAG18723.1 - 0.38 11.2 23.4 6.6 7.2 0.5 3.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG18723.1 - 0.42 10.8 2.6 1.5 9.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 OAG18723.1 - 3 6.4 13.1 1.6 7.3 0.1 3.8 4 0 0 4 4 4 0 AAA domain zf-Di19 PF05605.12 OAG18724.1 - 0.0065 16.7 0.5 0.065 13.5 0.0 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OAG18724.1 - 0.081 13.8 1.2 0.19 12.7 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAG18724.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type SMG1 PF15785.5 OAG18724.1 - 0.64 8.3 3.2 0.92 7.8 3.2 1.2 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Rtf2 PF04641.12 OAG18724.1 - 2.7 7.3 5.6 1.4 8.2 0.2 2.4 2 1 0 2 2 2 0 Rtf2 RING-finger GDPD PF03009.17 OAG18726.1 - 6.7e-15 55.5 0.0 1.1e-14 54.9 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TCO89 PF10452.9 OAG18728.1 - 1e-08 34.7 4.7 1e-08 34.7 4.7 3.8 2 2 1 3 3 3 1 TORC1 subunit TCO89 Dynamin_N PF00350.23 OAG18728.1 - 0.21 11.6 2.2 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Dynamin family Putative_PNPOx PF01243.20 OAG18730.1 - 2.3e-11 43.7 0.0 7e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 OAG18730.1 - 0.04 14.3 0.0 1.6 9.1 0.0 2.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG18730.1 - 0.063 13.9 0.1 0.16 12.6 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF5421 PF17458.2 OAG18730.1 - 0.15 11.4 0.3 0.27 10.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) GMC_oxred_N PF00732.19 OAG18731.1 - 1.4e-53 182.2 0.0 1.8e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG18731.1 - 6.3e-35 120.8 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG18731.1 - 1.5e-06 27.5 0.1 3.4e-05 23.1 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG18731.1 - 0.00014 21.2 0.3 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG18731.1 - 0.00032 20.4 0.3 0.039 13.5 0.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG18731.1 - 0.0018 17.5 0.1 0.56 9.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG18731.1 - 0.0063 15.8 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG18731.1 - 0.0065 15.2 0.1 0.077 11.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG18731.1 - 0.0068 16.6 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG18731.1 - 0.019 14.1 0.4 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG18731.1 - 0.042 12.9 0.7 0.065 12.3 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG18731.1 - 0.17 11.8 0.3 6.7 6.7 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MARVEL PF01284.23 OAG18732.1 - 0.00038 20.5 15.7 0.00046 20.2 15.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7tm_1 PF00001.21 OAG18732.1 - 0.25 10.7 6.2 0.4 10.0 5.7 1.4 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) MAT1 PF06391.13 OAG18733.1 - 2.3e-30 106.0 3.6 3e-30 105.6 3.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAG18733.1 - 3e-23 81.4 7.2 4.8e-23 80.8 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG18733.1 - 0.0014 18.9 5.9 0.0028 17.9 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain MTHFR_C PF12225.8 OAG18733.1 - 0.0039 16.8 0.1 0.0077 15.9 0.1 1.6 1 0 0 1 1 1 1 Methylene-tetrahydrofolate reductase C terminal DUF572 PF04502.13 OAG18733.1 - 0.0065 16.1 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C3HC4_2 PF13923.6 OAG18733.1 - 0.011 15.5 6.5 0.084 12.7 7.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG18733.1 - 0.02 14.8 7.7 0.089 12.8 8.0 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG18733.1 - 0.029 14.2 6.1 0.2 11.5 6.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG18733.1 - 0.035 14.0 7.6 0.19 11.6 7.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.7 OAG18733.1 - 0.036 13.9 1.4 0.085 12.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Zn_ribbon_17 PF17120.5 OAG18733.1 - 0.047 13.3 2.1 0.094 12.4 2.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 OAG18733.1 - 0.064 13.4 1.1 0.17 12.0 1.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAG18733.1 - 0.11 12.3 5.1 1.7 8.5 2.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2340 PF10209.9 OAG18733.1 - 0.16 12.4 1.3 0.43 11.0 0.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) RBD-FIP PF09457.10 OAG18733.1 - 0.4 10.6 1.5 2 8.4 0.4 2.5 3 0 0 3 3 3 0 FIP domain zf-RING_6 PF14835.6 OAG18733.1 - 1.4 8.8 4.9 2.5 8.0 1.5 2.6 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAG18733.1 - 2.7 7.9 8.0 11 6.0 1.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prefoldin_3 PF13758.6 OAG18734.1 - 3.1e-30 104.2 0.9 1e-29 102.5 0.9 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 OAG18734.1 - 2.3e-24 86.0 0.5 2.3e-24 86.0 0.5 5.5 6 2 0 6 6 6 2 Domain of unknown function (DUF3835) DUF5340 PF17275.2 OAG18734.1 - 0.012 15.8 9.0 0.1 12.7 1.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5340) Prefoldin PF02996.17 OAG18734.1 - 0.26 11.2 4.1 6.9 6.6 0.5 2.8 2 0 0 2 2 2 0 Prefoldin subunit FAM167 PF11652.8 OAG18734.1 - 0.39 11.2 2.1 13 6.3 0.1 2.8 2 0 0 2 2 2 0 FAM167 HIP1_clath_bdg PF16515.5 OAG18734.1 - 8.9 7.0 11.0 2 9.0 5.0 2.9 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atx10homo_assoc PF09759.9 OAG18735.1 - 1.3e-29 102.1 0.7 2.4e-27 94.8 0.3 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HMG_box PF00505.19 OAG18735.1 - 0.00043 20.6 0.1 0.0011 19.3 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG18735.1 - 0.0015 19.0 0.1 0.0046 17.5 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain DUF2514 PF10721.9 OAG18735.1 - 0.0047 17.0 4.0 0.0047 17.0 4.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2514) Med9 PF07544.13 OAG18735.1 - 0.11 12.6 0.9 0.36 10.9 0.9 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4094 PF13334.6 OAG18735.1 - 0.13 12.7 1.4 0.36 11.3 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4795 PF16043.5 OAG18735.1 - 0.14 11.7 1.9 0.38 10.3 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Glycohydro_20b2 PF14845.6 OAG18735.1 - 0.16 12.7 2.3 0.37 11.4 1.0 2.2 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like MRPL52 PF18699.1 OAG18735.1 - 0.18 12.0 1.7 6 7.1 1.1 2.7 2 0 0 2 2 2 0 Mitoribosomal protein mL52 AATF-Che1 PF13339.6 OAG18735.1 - 0.2 12.3 4.0 10 6.8 2.5 3.1 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF4349 PF14257.6 OAG18735.1 - 0.4 10.1 5.4 0.22 10.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) COesterase PF00135.28 OAG18736.1 - 9.8e-78 262.3 0.0 1.2e-77 261.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG18736.1 - 2.7e-06 27.4 0.1 9.8e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 OAG18737.1 - 6.7e-19 68.0 0.1 4.1e-17 62.1 0.1 2.6 2 1 0 2 2 2 2 Cytochrome P450 GTP_EFTU PF00009.27 OAG18739.1 - 7.4e-46 156.1 0.1 1.4e-45 155.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 OAG18739.1 - 9.4e-21 73.9 4.0 2.3e-20 72.6 4.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 OAG18739.1 - 4.5e-11 43.0 0.1 9.6e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAG18739.1 - 5.4e-07 29.7 0.1 0.0011 19.0 0.0 3.1 4 0 0 4 4 4 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAG18739.1 - 1.2e-05 25.6 0.0 3.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 OAG18739.1 - 0.001 19.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG18739.1 - 0.024 14.1 0.0 1.9 7.9 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Imm8 PF15586.6 OAG18739.1 - 0.035 14.1 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 8 FeoB_N PF02421.18 OAG18739.1 - 0.098 12.2 0.1 1.9 8.0 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B CysA_C_terminal PF17850.1 OAG18739.1 - 0.14 12.8 0.0 0.46 11.1 0.0 1.9 1 0 0 1 1 1 0 CysA C-terminal regulatory domain PTPA PF03095.15 OAG18740.1 - 1.9e-120 401.9 0.0 2.3e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Uso1_p115_head PF04869.14 OAG18741.1 - 0.0099 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region ING PF12998.7 OAG18741.1 - 3.8 8.1 8.4 19 5.9 4.0 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SR-25 PF10500.9 OAG18742.1 - 0.0098 15.5 6.7 0.0098 15.5 6.7 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein REV PF00424.18 OAG18742.1 - 0.035 14.1 1.2 0.076 13.0 0.6 1.9 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) TrkH PF02386.16 OAG18743.1 - 3.2e-115 385.4 2.3 3.2e-115 385.4 2.3 2.0 2 0 0 2 2 2 2 Cation transport protein SIS PF01380.22 OAG18746.1 - 2.3e-13 50.1 0.2 5.5e-13 48.9 0.2 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 OAG18746.1 - 7.4e-05 22.8 0.2 0.0062 16.5 0.1 2.3 1 1 1 2 2 2 2 SIS domain Acetyltransf_1 PF00583.25 OAG18747.1 - 4.3e-09 36.6 0.0 5.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG18747.1 - 1.3e-06 28.7 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG18747.1 - 4.6e-06 26.6 0.0 7.3e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TauD PF02668.16 OAG18748.1 - 2e-44 152.4 0.2 2.7e-44 152.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 OAG18748.1 - 0.15 12.0 0.2 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain Amino_oxidase PF01593.24 OAG18749.1 - 3.5e-41 142.0 0.1 1e-40 140.4 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG18749.1 - 2.9e-05 24.2 0.0 9.7e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG18749.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S20p PF01649.18 OAG18749.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 Pyr_redox_2 PF07992.14 OAG18749.1 - 0.08 12.2 0.0 0.64 9.2 0.0 2.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuc_L-PSP PF01042.21 OAG18750.1 - 6.6e-30 103.6 0.0 9.7e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_1 PF00561.20 OAG18751.1 - 6.2e-18 65.4 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG18751.1 - 2.5e-12 47.9 0.0 4.2e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 OAG18751.1 - 0.036 14.4 0.2 0.09 13.1 0.2 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF775 PF05603.12 OAG18752.1 - 0.043 13.4 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) NOA36 PF06524.12 OAG18752.1 - 3.1 7.0 13.1 4.4 6.5 13.1 1.1 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_34 PF05637.12 OAG18754.1 - 8.1e-06 25.7 4.5 5.8e-05 22.9 4.5 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 OAG18754.1 - 1.4e-05 25.2 0.5 2e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-C2H2_4 PF13894.6 OAG18755.1 - 0.0023 18.6 9.4 0.045 14.6 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG18755.1 - 0.0094 16.4 2.1 0.0094 16.4 2.1 3.1 2 1 0 2 2 2 1 Zinc finger, C2H2 type CHORD PF04968.12 OAG18755.1 - 0.17 12.6 0.3 0.43 11.3 0.3 1.7 1 0 0 1 1 1 0 CHORD Glyoxalase_3 PF13468.6 OAG18756.1 - 1.4e-07 31.8 0.0 3.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OAG18756.1 - 0.00015 22.0 0.3 0.0033 17.7 0.0 2.6 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2958 PF11171.8 OAG18757.1 - 0.081 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) DnaJ PF00226.31 OAG18758.1 - 2.8e-08 33.8 0.1 4.3e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3425 PF11905.8 OAG18759.1 - 9.7e-13 48.2 0.3 2e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAG18759.1 - 1.6e-09 37.7 9.1 3e-09 36.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 OAG18760.1 - 1.8e-72 243.3 7.6 2.6e-72 242.8 7.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Cu-oxidase_3 PF07732.15 OAG18761.1 - 2.5e-43 146.9 8.4 4.2e-40 136.5 0.7 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG18761.1 - 2.2e-39 134.3 6.8 9.9e-35 119.3 0.7 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OAG18761.1 - 4.2e-25 88.7 0.1 1.6e-23 83.6 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Herpes_IE1 PF07340.11 OAG18761.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Pup PF05639.11 OAG18761.1 - 0.23 12.4 1.6 0.73 10.8 1.6 1.8 1 0 0 1 1 1 0 Pup-like protein SET PF00856.28 OAG18762.1 - 9.7e-14 52.1 0.4 1.6e-12 48.1 0.1 2.7 2 1 0 2 2 2 1 SET domain DUF3038 PF11237.8 OAG18763.1 - 0.072 13.1 0.2 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) DEAD PF00270.29 OAG18765.1 - 2.3e-06 27.5 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase F-box PF00646.33 OAG18765.1 - 0.024 14.5 0.3 0.049 13.5 0.3 1.5 1 0 0 1 1 1 0 F-box domain ResIII PF04851.15 OAG18765.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FA_desaturase PF00487.24 OAG18767.1 - 3.5e-20 72.9 18.9 4.5e-20 72.6 18.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_trans_2_3 PF13632.6 OAG18767.1 - 0.035 14.0 2.7 0.062 13.2 2.7 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HRG PF16954.5 OAG18768.1 - 0.2 12.1 0.8 0.65 10.4 0.8 1.9 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MatE PF01554.18 OAG18771.1 - 1e-08 35.0 19.1 0.00055 19.6 1.7 3.6 3 1 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 OAG18771.1 - 2.7e-05 24.3 2.0 2.7e-05 24.3 2.0 3.9 3 1 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain FAD_binding_3 PF01494.19 OAG18773.1 - 1.3e-17 64.1 0.6 1.4e-10 41.0 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG18773.1 - 1.9e-05 24.8 0.3 6.3e-05 23.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG18773.1 - 3.8e-05 22.9 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG18773.1 - 5e-05 22.7 0.1 0.00011 21.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG18773.1 - 0.00012 21.3 0.4 0.00021 20.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG18773.1 - 0.00038 19.8 0.1 0.0008 18.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG18773.1 - 0.0044 15.8 0.2 0.0092 14.7 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG18773.1 - 0.011 14.9 0.2 0.017 14.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 OAG18773.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_68 PF02435.16 OAG18773.1 - 0.091 11.6 0.3 0.15 10.8 0.3 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase Aldolase_II PF00596.21 OAG18776.1 - 2.9e-33 115.4 0.2 4.1e-33 114.9 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HET PF06985.11 OAG18777.1 - 3.6e-17 63.1 6.6 8.3e-17 61.9 6.6 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-rbx1 PF12678.7 OAG18777.1 - 0.025 14.9 0.4 0.053 13.8 0.1 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain AnfG_VnfG PF03139.15 OAG18777.1 - 0.036 14.2 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Abhydrolase_1 PF00561.20 OAG18778.1 - 6e-17 62.1 0.1 3e-16 59.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG18778.1 - 1.2e-11 44.4 0.1 3e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG18778.1 - 1.4e-08 35.6 0.9 2.3e-08 34.9 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG18778.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 OAG18778.1 - 0.026 14.1 0.0 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 OAG18778.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 OAG18778.1 - 0.068 12.8 0.1 0.92 9.1 0.1 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 OAG18778.1 - 0.12 11.7 0.1 0.53 9.6 0.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Epimerase PF01370.21 OAG18779.1 - 7.1e-27 94.4 0.0 8.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG18779.1 - 2.7e-18 66.5 0.1 3.7e-18 66.0 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG18779.1 - 9.6e-14 51.0 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG18779.1 - 8.6e-13 48.0 0.5 4.8e-12 45.6 0.5 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG18779.1 - 6.4e-11 42.5 0.0 9.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG18779.1 - 1.9e-07 30.9 0.0 7e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 OAG18779.1 - 2.1e-05 24.5 0.0 6.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG18779.1 - 0.0001 21.5 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG18779.1 - 0.0018 17.8 0.1 0.015 14.8 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase PrmA PF06325.13 OAG18779.1 - 0.043 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pec_lyase_C PF00544.19 OAG18780.1 - 6.7e-11 42.2 8.2 4.1e-09 36.3 8.2 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG18780.1 - 0.0001 22.2 23.8 0.0017 18.2 11.5 2.5 1 1 1 2 2 2 2 Right handed beta helix region ArsA_ATPase PF02374.15 OAG18781.1 - 2.4e-117 391.5 0.1 2.8e-117 391.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAG18781.1 - 1.9e-15 57.2 0.2 2.3e-13 50.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OAG18781.1 - 2.4e-13 50.3 0.0 5.4e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OAG18781.1 - 1.2e-07 31.5 0.9 4.7e-05 23.0 0.0 2.6 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 OAG18781.1 - 8.4e-07 28.8 0.3 0.00026 20.7 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 OAG18781.1 - 2e-06 27.5 0.0 4.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 OAG18781.1 - 9.1e-06 25.3 0.0 3.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 OAG18781.1 - 0.035 13.7 0.6 0.17 11.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 OAG18781.1 - 0.044 13.1 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein PhoH PF02562.16 OAG18781.1 - 0.049 13.1 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 OAG18781.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 OAG18781.1 - 0.084 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OAG18781.1 - 0.12 13.0 0.6 0.28 11.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAG18781.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 OAG18781.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 OAG18781.1 - 0.17 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MipZ PF09140.11 OAG18781.1 - 0.2 10.9 0.1 0.72 9.1 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ AAA_24 PF13479.6 OAG18781.1 - 0.21 11.3 0.2 1.7 8.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2537 PF10801.8 OAG18781.1 - 0.22 11.8 0.0 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Lipase_3 PF01764.25 OAG18782.1 - 3.2e-31 108.1 0.0 4.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 OAG18782.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 OAG18782.1 - 0.00086 20.0 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG18782.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 OAG18782.1 - 0.0084 15.7 0.3 0.053 13.1 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 OAG18782.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 OAG18782.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Vma12 PF11712.8 OAG18783.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2062 PF09835.9 OAG18783.1 - 1.5 8.7 10.3 5.9 6.7 1.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) SNF2_N PF00176.23 OAG18784.1 - 2.1e-73 247.1 0.0 3.9e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAG18784.1 - 2.4e-40 137.1 2.9 6.1e-40 135.8 1.1 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 OAG18784.1 - 2.1e-35 121.8 1.9 2.1e-35 121.8 1.9 3.6 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 OAG18784.1 - 4.2e-18 65.7 0.0 1.3e-17 64.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG18784.1 - 2.4e-09 37.4 0.0 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OAG18784.1 - 5.4e-05 23.3 0.2 0.15 12.2 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 OAG18784.1 - 0.0001 22.0 0.0 0.00043 20.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 OAG18784.1 - 0.00091 18.5 0.3 0.0023 17.2 0.3 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 OAG18784.1 - 0.0015 18.3 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAG18784.1 - 0.0033 16.7 0.0 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 OAG18784.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arginase PF00491.21 OAG18785.1 - 1.3e-15 57.6 0.0 1.7e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family HET PF06985.11 OAG18786.1 - 1.2e-11 45.2 5.8 5.4e-09 36.5 0.2 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Amidase PF01425.21 OAG18787.1 - 2.2e-33 115.9 0.8 3.4e-33 115.3 0.8 1.2 1 0 0 1 1 1 1 Amidase HET PF06985.11 OAG18788.1 - 4.9e-26 91.8 0.0 7.4e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 OAG18789.1 - 7.8e-15 55.0 0.1 6.5e-09 35.5 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG18789.1 - 4e-07 29.6 0.0 1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG18789.1 - 4.4e-06 26.5 0.5 0.00039 20.1 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG18789.1 - 8.1e-05 21.9 0.2 0.00016 20.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG18789.1 - 0.00066 19.9 0.2 0.0015 18.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG18789.1 - 0.00082 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG18789.1 - 0.0023 18.4 0.3 0.017 15.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG18789.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG18789.1 - 0.011 14.4 0.2 0.035 12.8 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 OAG18789.1 - 0.014 14.5 0.1 0.049 12.7 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG18789.1 - 0.018 14.1 0.1 0.045 12.8 0.1 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG18789.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 OAG18789.1 - 0.051 14.2 0.5 15 6.3 0.4 3.3 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 OAG18789.1 - 0.071 13.1 0.2 3.1 7.8 0.0 2.3 1 1 1 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAG18789.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 OAG18790.1 - 4.8e-21 75.6 0.0 4.2e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG18790.1 - 7.3e-12 46.4 0.1 1e-11 45.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG18790.1 - 2.4e-09 36.8 0.0 8.2e-08 31.8 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG18790.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2231 PF09990.9 OAG18791.1 - 4.2e-10 40.0 0.2 6.5e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) zf-C2H2_jaz PF12171.8 OAG18792.1 - 0.019 15.2 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG18792.1 - 0.025 14.9 0.2 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OAG18792.1 - 0.029 15.2 2.8 0.11 13.4 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG18792.1 - 0.063 13.8 1.7 0.13 12.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 OAG18792.1 - 0.076 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TMEM119 PF15724.5 OAG18799.1 - 0.0022 18.1 3.7 0.0028 17.8 3.7 1.1 1 0 0 1 1 1 1 TMEM119 family VSP PF03302.13 OAG18799.1 - 0.0025 16.7 0.3 0.0029 16.5 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OAG18799.1 - 0.0067 16.5 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 Podoplanin MSA-2c PF12238.8 OAG18799.1 - 0.13 12.3 5.4 0.16 11.9 5.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c HET PF06985.11 OAG18800.1 - 2.6e-23 83.0 0.1 5.5e-22 78.7 0.1 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRAM1 PF08390.11 OAG18800.1 - 0.0071 16.0 0.0 7.3 6.3 0.0 3.3 3 0 0 3 3 3 2 TRAM1-like protein FAD-oxidase_C PF02913.19 OAG18801.1 - 2e-48 165.2 0.0 2.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG18801.1 - 3.3e-31 107.9 0.1 1.2e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain COesterase PF00135.28 OAG18802.1 - 1.2e-59 202.6 0.0 1.7e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG18802.1 - 0.011 15.6 0.0 0.15 11.9 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 OAG18804.1 - 8.3e-59 199.4 0.0 1.1e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG18804.1 - 1.7e-31 109.7 0.0 3.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG18804.1 - 0.00021 21.0 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG18804.1 - 0.00039 20.6 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG18804.1 - 0.005 16.0 0.0 0.046 12.8 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG18804.1 - 0.0059 15.9 0.1 0.76 9.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG18804.1 - 0.0064 15.8 0.0 0.072 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG18804.1 - 0.063 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 OAG18804.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG18804.1 - 0.17 11.1 0.1 0.41 9.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Med1 PF10744.9 OAG18805.1 - 1.2e-76 258.5 0.0 1.7e-76 258.0 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF1179 PF06678.11 OAG18805.1 - 0.045 13.7 0.5 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Forkhead_N PF08430.12 OAG18805.1 - 0.65 10.6 10.2 1.3 9.7 10.2 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region SVIP PF15811.5 OAG18806.1 - 0.01 16.3 2.5 0.019 15.4 2.5 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein ZF-HD_dimer PF04770.12 OAG18806.1 - 0.18 12.1 5.3 0.66 10.4 5.3 2.0 1 1 0 1 1 1 0 ZF-HD protein dimerisation region GFA PF04828.14 OAG18807.1 - 1.3e-25 89.6 0.1 1.8e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 OAG18807.1 - 0.01 16.3 0.1 0.01 16.3 0.1 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Tfb5 PF06331.12 OAG18808.1 - 1e-23 83.1 1.5 1.1e-23 83.0 1.5 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Med4 PF10018.9 OAG18808.1 - 0.0036 17.0 1.6 0.0037 17.0 1.6 1.0 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Citrate_ly_lig PF08218.11 OAG18808.1 - 0.064 12.9 0.1 0.072 12.8 0.1 1.0 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF3783 PF12646.7 OAG18808.1 - 0.07 13.1 0.5 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Chordopox_A13L PF05961.11 OAG18809.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEM252 PF15664.5 OAG18809.1 - 0.33 10.7 2.5 5.1 6.8 0.4 2.7 2 1 1 3 3 3 0 Transmembrane protein 252 family Pro_CA PF00484.19 OAG18810.1 - 0.0067 16.7 0.1 0.012 15.9 0.1 1.3 1 1 0 1 1 1 1 Carbonic anhydrase GMC_oxred_C PF05199.13 OAG18811.1 - 4.6e-28 98.6 0.0 9.4e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG18811.1 - 6e-28 98.1 0.0 2.8e-26 92.6 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG18811.1 - 0.0003 20.1 0.0 0.0006 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG18811.1 - 0.0027 17.9 0.1 0.0083 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG18811.1 - 0.038 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAG18811.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 OAG18811.1 - 0.12 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG18811.1 - 0.18 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAG18811.1 - 0.27 10.2 0.2 0.39 9.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Gln-synt_C PF00120.24 OAG18813.1 - 1e-16 60.9 0.0 1.7e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAG18813.1 - 1.2e-13 50.5 0.0 2.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 OAG18814.1 - 8.2e-44 150.0 46.6 5.8e-43 147.2 46.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily SPT_ssu-like PF11779.8 OAG18814.1 - 0.12 12.0 2.4 0.84 9.3 0.6 3.1 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like DUF412 PF04217.13 OAG18814.1 - 1.5 8.7 3.7 1.4 8.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Isochorismatase PF00857.20 OAG18815.1 - 7.6e-33 114.1 0.3 1.9e-30 106.3 0.3 2.6 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 OAG18815.1 - 1.5e-24 87.3 0.2 3.8e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.6 OAG18815.1 - 9e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG18815.1 - 0.026 14.7 0.0 0.085 13.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG18815.1 - 0.16 12.2 0.0 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HR_lesion PF05514.11 OAG18816.1 - 0.052 13.7 0.1 0.075 13.2 0.1 1.2 1 0 0 1 1 1 0 HR-like lesion-inducing SBF PF01758.16 OAG18817.1 - 0.22 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family AMP-binding PF00501.28 OAG18818.1 - 8.3e-20 70.8 0.0 6.9e-19 67.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme SRAP PF02586.14 OAG18821.1 - 4.5e-87 291.2 0.0 6.2e-87 290.7 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_12 PF13424.6 OAG18822.1 - 0.00015 21.9 5.6 0.074 13.3 3.2 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG18822.1 - 0.015 15.3 14.6 0.54 10.5 0.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG18822.1 - 0.017 14.5 0.5 0.44 9.9 0.3 2.3 2 0 0 2 2 2 0 MalT-like TPR region RPN7 PF10602.9 OAG18822.1 - 0.032 13.9 0.0 2.8 7.6 0.1 3.1 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 OAG18822.1 - 0.053 14.3 7.3 20 6.3 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Arm-DNA-bind_3 PF13356.6 OAG18822.1 - 0.059 13.7 1.8 21 5.6 0.5 3.2 3 0 0 3 3 3 0 Arm DNA-binding domain TPR_10 PF13374.6 OAG18822.1 - 3.5 7.6 6.7 4.1 7.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG18823.1 - 0.0006 19.2 1.0 0.0018 17.7 0.0 2.3 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins DUF2235 PF09994.9 OAG18824.1 - 5.5e-84 281.9 0.1 6.6e-84 281.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HET PF06985.11 OAG18825.1 - 1.3e-22 80.7 0.3 2.4e-22 79.8 0.3 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IMS PF00817.20 OAG18825.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 impB/mucB/samB family Cep57_MT_bd PF06657.13 OAG18828.1 - 3.2e-20 72.4 0.1 3.2e-20 72.4 0.1 7.0 6 1 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 OAG18828.1 - 6.7e-20 70.9 6.0 6.7e-20 70.9 6.0 7.1 4 1 1 5 5 5 1 Centrosome localisation domain of PPC89 HALZ PF02183.18 OAG18828.1 - 0.034 14.4 36.9 0.089 13.0 4.1 6.5 5 1 1 6 6 6 0 Homeobox associated leucine zipper ESSS PF10183.9 OAG18828.1 - 1.5 9.1 5.1 10 6.4 5.1 2.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.25 OAG18829.1 - 4e-43 147.7 0.0 1.5e-42 145.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18829.1 - 1.3e-28 100.0 0.0 1.9e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG18829.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG18829.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldose_epim PF01263.20 OAG18830.1 - 1.5e-41 142.7 0.0 1.6e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_1 PF00190.22 OAG18832.1 - 7.2e-35 119.8 0.1 2.8e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG18832.1 - 2.9e-22 78.2 0.1 7e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG18832.1 - 1.5e-08 34.2 0.0 0.00073 19.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAG18832.1 - 1.3e-06 28.4 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OAG18832.1 - 1.4e-06 28.2 0.1 0.00065 19.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 OAG18832.1 - 0.0057 16.3 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.11 OAG18832.1 - 0.012 15.6 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) DUF2288 PF10052.9 OAG18833.1 - 0.078 13.1 0.0 0.49 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) HET PF06985.11 OAG18836.1 - 6.6e-14 52.5 2.4 2.8e-10 40.7 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WLM PF08325.10 OAG18837.1 - 5.8e-21 75.4 0.7 2.4e-20 73.4 0.7 1.8 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAG18837.1 - 0.0029 17.7 0.6 0.016 15.2 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF45 Glyco_transf_34 PF05637.12 OAG18839.1 - 0.063 13.0 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family CDC45 PF02724.14 OAG18841.1 - 0.25 9.6 3.4 2 6.6 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DJ-1_PfpI PF01965.24 OAG18842.1 - 3.6e-10 39.9 0.0 1.5e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG18842.1 - 3.3e-05 23.6 0.0 0.00031 20.5 0.0 2.2 2 1 0 2 2 2 1 ThiJ/PfpI family-like EthD PF07110.11 OAG18843.1 - 2.6e-05 25.3 0.0 6.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 EthD domain HrpB7 PF09486.10 OAG18844.1 - 0.012 16.1 5.5 0.018 15.5 5.5 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HWE_HK PF07536.14 OAG18847.1 - 0.054 14.2 0.6 0.17 12.6 0.6 1.8 1 0 0 1 1 1 0 HWE histidine kinase DUF2303 PF10065.9 OAG18849.1 - 0.002 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) Mito_carr PF00153.27 OAG18851.1 - 2.5e-20 72.2 4.7 7.4e-08 32.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 OAG18851.1 - 0.0003 20.8 0.4 0.0045 17.0 0.0 2.5 2 1 0 2 2 2 1 Colicin V production protein DUF3309 PF11752.8 OAG18851.1 - 1.7 8.8 6.1 2.3 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Ank_4 PF13637.6 OAG18855.1 - 0.00058 20.4 0.0 0.00076 20.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HET PF06985.11 OAG18856.1 - 2e-24 86.6 0.5 3.4e-24 85.9 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rav1p_C PF12234.8 OAG18857.1 - 7.1e-274 910.1 0.1 1.2e-273 909.4 0.1 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal PrmA PF06325.13 OAG18857.1 - 6.5e-12 45.5 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAG18857.1 - 2.1e-11 43.9 0.0 5.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG18857.1 - 5.1e-10 39.9 0.0 2e-09 38.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG18857.1 - 3.2e-07 30.9 0.0 1.7e-06 28.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG18857.1 - 8.2e-07 29.0 0.0 3.7e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG18857.1 - 1.2e-05 24.9 0.1 2.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OAG18857.1 - 0.0002 21.4 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAG18857.1 - 0.00058 20.9 0.7 0.0062 17.5 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG18857.1 - 0.0011 19.7 0.0 0.0034 18.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG18857.1 - 0.0016 17.9 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG18857.1 - 0.0058 16.0 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 OAG18857.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 OAG18857.1 - 0.04 13.6 0.1 0.094 12.3 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OAG18857.1 - 0.041 12.8 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 OAG18857.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 OAG18857.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.27 OAG18858.1 - 5.7e-20 72.2 1.4 7e-20 71.9 1.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG18858.1 - 0.0063 16.1 0.1 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CysG_dimeriser PF10414.9 OAG18858.1 - 0.027 14.2 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Sulfotransfer_3 PF13469.6 OAG18858.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Sulfotransferase family ADH_zinc_N_2 PF13602.6 OAG18859.1 - 2.9e-15 57.5 0.0 6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG18859.1 - 1.2e-10 41.5 0.0 2.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG18859.1 - 9.2e-06 25.5 0.1 4.1e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG18859.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Hydrolase_4 PF12146.8 OAG18860.1 - 2.9e-13 49.7 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG18860.1 - 4.6e-10 40.5 0.1 6.1e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 OAG18860.1 - 1e-07 30.9 0.1 3.3e-05 22.7 0.1 2.7 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OAG18860.1 - 4.4e-07 29.8 0.0 5.6e-07 29.4 0.0 1.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 OAG18860.1 - 0.00024 19.7 0.2 0.22 10.0 0.0 2.4 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 OAG18860.1 - 0.0027 17.2 0.3 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG18860.1 - 0.11 12.5 0.0 0.55 10.1 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PHB_depo_C PF06850.11 OAG18860.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PHB de-polymerase C-terminus SnoaL_2 PF12680.7 OAG18861.1 - 0.0017 19.0 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 OAG18861.1 - 0.036 14.2 0.1 0.049 13.7 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Pectate_lyase_3 PF12708.7 OAG18861.1 - 0.12 12.2 0.9 0.26 11.1 0.2 1.7 1 1 1 2 2 2 0 Pectate lyase superfamily protein HEPN_LA2681 PF18733.1 OAG18861.1 - 0.14 11.4 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 LA2681-like HEPN Zn_clus PF00172.18 OAG18862.1 - 1.5e-05 25.0 9.3 2.3e-05 24.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG18862.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG18863.1 - 2.3e-33 115.6 25.3 2.3e-33 115.6 25.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2567 PF10821.8 OAG18863.1 - 1.5 8.9 10.6 0.14 12.2 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2567) Peptidase_A8 PF01252.18 OAG18863.1 - 6.6 7.0 8.5 2 8.7 0.2 3.2 3 1 0 3 3 3 0 Signal peptidase (SPase) II DUF1907 PF08925.11 OAG18864.1 - 7.7e-110 366.8 0.0 8.8e-110 366.6 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) adh_short_C2 PF13561.6 OAG18865.1 - 8.8e-58 195.6 1.8 1.5e-57 194.9 1.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18865.1 - 1.5e-42 145.3 0.3 2.3e-42 144.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.8 OAG18865.1 - 8.7e-15 54.4 0.1 1.7e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18865.1 - 5.9e-09 35.9 12.9 1.2e-08 34.9 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.10 OAG18865.1 - 0.00046 20.1 0.5 0.00082 19.3 0.1 1.6 2 0 0 2 2 2 1 KR domain Peptidase_S8 PF00082.22 OAG18866.1 - 1.7e-25 89.9 12.4 2.9e-25 89.2 12.4 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG18866.1 - 7.5e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1889 PF08986.10 OAG18866.1 - 0.0017 18.7 0.1 1.1 9.6 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1889) Peptidase_M24_C PF16188.5 OAG18867.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 DUF433 PF04255.14 OAG18868.1 - 0.00054 19.8 0.1 6.9 6.6 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF433) RabGAP-TBC PF00566.18 OAG18869.1 - 2.8e-51 174.2 0.2 9.9e-51 172.4 0.0 2.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Spore_YpjB PF09577.10 OAG18869.1 - 0.18 11.6 3.2 0.54 10.0 3.2 1.8 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) YabA PF06156.13 OAG18869.1 - 0.42 11.3 9.6 3.7 8.2 0.0 3.9 4 0 0 4 4 4 0 Initiation control protein YabA FlaC_arch PF05377.11 OAG18869.1 - 3.9 7.9 5.2 44 4.6 0.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) WSC PF01822.19 OAG18871.1 - 4.6e-18 65.2 12.5 4.6e-18 65.2 12.5 2.4 2 0 0 2 2 2 1 WSC domain WSC PF01822.19 OAG18873.1 - 1.5e-16 60.3 13.0 1.5e-16 60.3 13.0 2.3 2 0 0 2 2 2 1 WSC domain DivIC PF04977.15 OAG18873.1 - 0.07 12.9 0.9 0.11 12.2 0.9 1.2 1 0 0 1 1 1 0 Septum formation initiator KASH_CCD PF14662.6 OAG18873.1 - 0.075 12.8 1.4 0.11 12.3 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HET PF06985.11 OAG18874.1 - 3.5e-13 50.1 6.5 6.4e-10 39.5 0.2 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Suc_Fer-like PF06999.12 OAG18875.1 - 1.2e-71 240.6 0.0 1.7e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like REPA_OB_2 PF16900.5 OAG18876.1 - 0.036 14.0 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Replication protein A OB domain Toxin_R_bind_N PF07953.12 OAG18876.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Tyrosinase PF00264.20 OAG18877.1 - 2e-37 129.7 2.9 9.4e-22 78.4 0.2 3.1 2 1 1 3 3 3 2 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG18877.1 - 1.9e-22 80.2 0.0 4.4e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain MFS_1 PF07690.16 OAG18881.1 - 1.8e-36 125.8 45.9 1.1e-35 123.2 46.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG18881.1 - 4.3e-19 68.4 23.2 7.1e-19 67.7 23.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AATase PF07247.12 OAG18882.1 - 5.8e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 OAG18882.1 - 0.0045 15.7 0.8 3.4 6.2 0.0 2.7 3 0 0 3 3 3 2 Condensation domain Aminotran_1_2 PF00155.21 OAG18884.1 - 7.9e-28 97.7 0.0 1.3e-27 97.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II PBP_like PF12727.7 OAG18884.1 - 0.00081 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Cys_Met_Meta_PP PF01053.20 OAG18884.1 - 0.003 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ketoacyl-synt PF00109.26 OAG18885.1 - 1.7e-69 234.2 0.1 8.8e-69 231.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG18885.1 - 1.1e-54 185.1 0.0 2.5e-54 183.9 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OAG18885.1 - 5.5e-47 160.8 0.1 1.1e-46 159.9 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG18885.1 - 8.1e-46 156.6 0.0 1.4e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG18885.1 - 4.5e-34 117.0 0.0 1.4e-33 115.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG18885.1 - 2.9e-16 60.0 0.0 8.4e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG18885.1 - 8.4e-16 59.2 0.0 1.3e-14 55.4 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 OAG18885.1 - 7.9e-15 55.3 0.2 2.9e-09 37.4 0.0 3.0 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 OAG18885.1 - 1.5e-14 54.1 0.0 1.6e-13 50.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG18885.1 - 1.4e-12 48.1 0.0 1.7e-11 44.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG18885.1 - 5.2e-12 45.8 0.0 1.5e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG18885.1 - 7.3e-12 45.8 0.0 3.3e-11 43.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG18885.1 - 9.4e-11 41.5 0.0 2.9e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 OAG18885.1 - 6.9e-10 39.0 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 OAG18885.1 - 1.2e-08 35.1 0.2 3.2e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 OAG18885.1 - 1.9e-08 33.9 0.0 8.9e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 OAG18885.1 - 2.6e-05 23.7 0.2 7.1e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 OAG18885.1 - 0.00011 21.9 0.0 0.00044 19.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 OAG18885.1 - 0.0013 18.6 0.1 0.0039 17.0 0.1 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 OAG18885.1 - 0.0041 17.0 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 OAG18885.1 - 0.025 14.3 0.4 0.063 13.0 0.4 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF915 PF06028.11 OAG18885.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PALP PF00291.25 OAG18885.1 - 1.8 7.9 4.8 0.62 9.4 0.2 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme MerR-DNA-bind PF09278.11 OAG18886.1 - 0.032 14.7 2.8 2.5 8.7 1.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding FAD_binding_4 PF01565.23 OAG18887.1 - 1.1e-27 96.5 0.5 1.6e-27 95.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG18887.1 - 1.2e-15 57.8 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain NACHT PF05729.12 OAG18888.1 - 6.2e-09 36.0 1.6 1.6e-08 34.7 0.1 2.5 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 OAG18888.1 - 0.00023 21.6 2.4 0.0013 19.2 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 OAG18888.1 - 0.003 18.1 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG18888.1 - 0.0039 17.7 0.1 0.04 14.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 OAG18888.1 - 0.0056 16.9 0.2 0.064 13.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain Ank PF00023.30 OAG18888.1 - 0.012 16.0 0.1 2.5 8.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat AAA_29 PF13555.6 OAG18888.1 - 0.047 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_4 PF13637.6 OAG18888.1 - 0.072 13.7 0.0 3.5 8.3 0.0 3.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) RNA_helicase PF00910.22 OAG18888.1 - 0.092 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SesA PF17107.5 OAG18888.1 - 1.3 9.3 10.1 0.37 11.0 1.7 3.6 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Glyco_hydro_88 PF07470.13 OAG18889.1 - 6.5e-14 51.7 0.3 9.8e-14 51.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 OAG18889.1 - 0.0015 18.1 0.1 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus MFS_1 PF07690.16 OAG18891.1 - 1.3e-18 67.1 25.5 1.3e-18 67.1 25.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MENTAL PF10457.9 OAG18891.1 - 0.12 12.2 4.2 0.17 11.7 0.4 2.3 2 1 0 2 2 2 0 Cholesterol-capturing domain HTH_Tnp_Tc5 PF03221.16 OAG18892.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 OAG18892.1 - 0.0018 18.0 1.9 0.049 13.4 0.0 3.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 OAG18892.1 - 0.0025 17.9 0.4 0.0065 16.6 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Fungal_trans PF04082.18 OAG18893.1 - 1.1e-07 31.1 1.5 1.1e-07 31.1 1.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 OAG18893.1 - 0.046 14.0 0.2 0.15 12.4 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG18893.1 - 0.11 13.0 1.0 0.41 11.2 1.0 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type adh_short PF00106.25 OAG18894.1 - 2.5e-36 125.0 0.0 3.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18894.1 - 2.6e-21 76.2 0.0 3.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18894.1 - 4.4e-09 36.5 0.0 9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG18894.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HET PF06985.11 OAG18895.1 - 1.2e-20 74.3 1.3 2.1e-20 73.6 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 OAG18897.1 - 8.9e-49 166.2 0.0 1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG18897.1 - 1.7e-37 128.8 0.0 2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG18897.1 - 5.5e-09 36.2 0.1 7.7e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 KR domain CcmE PF03100.15 OAG18897.1 - 0.039 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 CcmE Epimerase PF01370.21 OAG18897.1 - 0.094 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EMP24_GP25L PF01105.24 OAG18898.1 - 7.2e-43 146.6 0.0 9e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 OAG18898.1 - 0.1 10.7 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ribonuc_L-PSP PF01042.21 OAG18899.1 - 1e-10 41.7 0.0 1.1e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-C2H2 PF00096.26 OAG18900.1 - 2.9e-07 30.6 13.2 0.0021 18.4 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG18900.1 - 0.00076 19.8 4.0 0.00076 19.8 4.0 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG18900.1 - 0.026 14.8 0.7 0.1 12.9 0.7 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG18900.1 - 0.094 13.6 11.5 1.6 9.8 2.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG18900.1 - 0.16 12.0 2.5 0.41 10.7 2.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG18900.1 - 2.7 7.8 9.4 0.17 11.7 1.5 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_clus PF00172.18 OAG18901.1 - 2.8e-08 33.7 10.3 4.9e-08 33.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 OAG18902.1 - 1.8e-40 138.6 0.0 2.6e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG18902.1 - 3.2e-21 75.8 0.0 8.6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG18902.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG18902.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TMEM251 PF15190.6 OAG18903.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 251 ISG65-75 PF11727.8 OAG18904.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein SKG6 PF08693.10 OAG18905.1 - 2e-05 23.9 1.6 4.6e-05 22.7 1.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OAG18905.1 - 9.2e-05 22.1 0.2 0.00018 21.2 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4328 PF14219.6 OAG18905.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) VSP PF03302.13 OAG18905.1 - 0.0092 14.9 0.1 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein LapA_dom PF06305.11 OAG18905.1 - 0.011 15.5 0.1 0.011 15.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CcmD PF04995.14 OAG18905.1 - 0.014 15.5 0.4 0.031 14.3 0.4 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF202 PF02656.15 OAG18905.1 - 0.029 14.8 0.7 0.061 13.8 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) EphA2_TM PF14575.6 OAG18905.1 - 0.053 14.4 0.0 0.084 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 OAG18905.1 - 0.06 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NfeD PF01957.18 OAG18905.1 - 0.09 13.2 0.2 0.34 11.3 0.2 2.1 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Gemini_mov PF01708.16 OAG18905.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein Holin_BhlA PF10960.8 OAG18905.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 BhlA holin family Rax2 PF12768.7 OAG18905.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 OAG18905.1 - 0.15 11.9 0.2 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 OAG18906.1 - 0.0042 17.9 0.0 0.013 16.4 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OAG18906.1 - 0.01 15.2 1.3 0.018 14.5 1.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 OAG18906.1 - 0.033 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A Syndecan PF01034.20 OAG18906.1 - 0.076 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain NfeD PF01957.18 OAG18906.1 - 0.12 12.8 0.3 0.74 10.2 0.3 2.1 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding LapA_dom PF06305.11 OAG18906.1 - 0.12 12.2 1.5 0.2 11.5 1.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mid2 PF04478.12 OAG18906.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Saf_2TM PF18303.1 OAG18906.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Aminotran_1_2 PF00155.21 OAG18907.1 - 1.1e-36 126.8 0.0 1.2e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II V_ATPase_I PF01496.19 OAG18908.1 - 0 1048.6 0.0 0 1048.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 OAG18908.1 - 0.0022 17.6 2.9 0.8 9.2 0.5 2.2 2 0 0 2 2 2 2 Intermediate filament protein CheZ PF04344.13 OAG18908.1 - 0.024 14.5 2.5 0.089 12.7 0.2 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ THP2 PF09432.10 OAG18908.1 - 0.029 14.4 0.3 0.11 12.6 0.3 1.9 1 0 0 1 1 1 0 Tho complex subunit THP2 Baculo_PEP_C PF04513.12 OAG18908.1 - 0.11 12.5 0.8 0.74 9.9 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.10 OAG18908.1 - 0.17 11.9 1.3 0.42 10.6 0.2 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain BLOC1_2 PF10046.9 OAG18908.1 - 0.4 11.0 1.8 2.1 8.7 0.4 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OAG18908.1 - 0.46 10.5 2.2 5.8 7.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 OAG18908.1 - 4.4 7.2 6.4 13 5.7 0.1 4.4 6 0 0 6 6 6 0 DASH complex subunit Dam1 Btz PF09405.10 OAG18909.1 - 1.7e-26 93.0 2.6 1.7e-26 93.0 2.6 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DUF4193 PF13834.6 OAG18909.1 - 0.33 11.5 4.6 0.76 10.3 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Torus PF16131.5 OAG18910.1 - 8.1e-07 29.7 3.4 2.5e-06 28.1 3.4 1.8 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 OAG18910.1 - 2.2e-06 27.5 4.8 3.9e-06 26.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG18910.1 - 8.8e-06 25.4 2.2 1.7e-05 24.5 2.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG18910.1 - 3e-05 23.8 0.8 5.8e-05 22.9 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAG18910.1 - 0.0065 16.9 3.5 0.014 15.8 3.5 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OAG18910.1 - 0.019 15.1 0.2 0.049 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family Sec1 PF00995.23 OAG18911.1 - 1.9e-116 390.6 0.0 2.1e-116 390.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF5394 PF17372.2 OAG18911.1 - 0.1 12.1 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5394) HrpJ PF07201.11 OAG18911.1 - 0.12 12.7 0.4 0.23 11.8 0.4 1.4 1 0 0 1 1 1 0 HrpJ-like domain HET PF06985.11 OAG18912.1 - 1.4e-13 51.5 0.0 2.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Usp PF00582.26 OAG18913.1 - 2.1e-20 73.7 0.8 4.2e-19 69.5 0.8 2.7 1 1 0 1 1 1 1 Universal stress protein family Ribosomal_S7 PF00177.21 OAG18914.1 - 4.6e-29 101.0 0.0 7.1e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Piwi PF02171.17 OAG18915.1 - 3.2e-77 259.8 0.0 4.7e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG18915.1 - 3.9e-19 69.6 0.1 1.2e-18 68.0 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG18915.1 - 8.5e-13 47.8 0.1 1.9e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAG18915.1 - 5.5e-12 45.8 0.2 1.3e-11 44.7 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 OAG18915.1 - 2.2e-05 24.3 0.0 6.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 PAZ domain Baculo_PEP_C PF04513.12 OAG18916.1 - 0.39 10.8 5.5 6 6.9 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 OAG18916.1 - 1 8.9 5.2 1.8 8.1 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HET PF06985.11 OAG18917.1 - 8.2e-27 94.4 0.0 1.6e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG18918.1 - 6.4e-38 130.6 0.0 9.8e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18918.1 - 4e-24 85.3 0.0 8.2e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 OAG18919.1 - 1.2e-86 291.4 13.7 3.1e-86 290.0 13.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG18919.1 - 8.9e-28 97.2 48.3 1.8e-23 83.1 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAG18919.1 - 1.6 7.1 8.2 4.3 5.6 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Cupin_2 PF07883.11 OAG18920.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ppnp PF06865.11 OAG18920.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase AIM5 PF17050.5 OAG18920.1 - 1.2 10.0 4.2 0.41 11.5 0.5 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 Pantoate_transf PF02548.15 OAG18921.1 - 1.2e-108 362.4 0.5 1.4e-108 362.2 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAG18921.1 - 8.8e-08 31.9 0.2 1.5e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 OAG18921.1 - 0.046 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) Aminotran_5 PF00266.19 OAG18921.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V UQ_con PF00179.26 OAG18922.1 - 1.6e-35 121.8 0.1 2.1e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_1 PF00561.20 OAG18923.1 - 3.6e-15 56.3 0.1 4.8e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG18923.1 - 1.1e-07 32.7 0.0 1.4e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG18923.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 OAG18924.1 - 2.4e-53 181.6 0.0 7.8e-35 120.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1254 PF06863.12 OAG18925.1 - 2.8e-26 92.2 0.4 7.3e-26 90.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 OAG18925.1 - 4.1e-26 91.6 0.0 7.9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Recombinase PF07508.13 OAG18926.1 - 0.067 13.6 0.1 0.098 13.1 0.1 1.2 1 1 0 1 1 1 0 Recombinase HET PF06985.11 OAG18927.1 - 5e-35 121.0 0.0 9e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 OAG18927.1 - 5.7e-07 29.2 9.7 1.6e-06 27.8 9.7 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type Glyco_hydro_48 PF02011.15 OAG18928.1 - 0.011 14.3 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 AMP-binding PF00501.28 OAG18929.1 - 5.1e-77 259.3 0.0 7.5e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 OAG18929.1 - 9.5e-74 248.1 0.0 2.1e-73 247.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 OAG18929.1 - 2.5e-59 201.1 0.1 4e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 OAG18929.1 - 1.9e-54 184.3 0.1 9e-52 175.6 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 OAG18929.1 - 8.5e-49 166.4 0.0 1.4e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG18929.1 - 1.8e-43 149.3 0.0 4.4e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG18929.1 - 2.7e-33 114.5 0.4 7.6e-32 109.8 0.1 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 OAG18929.1 - 2.2e-32 112.2 0.1 3.9e-31 108.2 0.1 2.7 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 OAG18929.1 - 6.5e-18 65.3 0.0 4.8e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG18929.1 - 2.1e-16 60.4 0.0 6.5e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OAG18929.1 - 3.9e-16 59.1 0.8 3.9e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 OAG18929.1 - 1.9e-12 47.2 0.0 3.5e-11 43.0 0.1 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 OAG18929.1 - 9.5e-12 45.5 0.0 1.5e-10 41.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG18929.1 - 9.1e-11 41.9 0.0 2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG18929.1 - 9.8e-10 38.2 0.1 3.6e-06 26.6 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_11 PF08241.12 OAG18929.1 - 2e-08 34.8 0.0 7.3e-07 29.8 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG18929.1 - 1.5e-07 31.3 0.0 4.8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 OAG18929.1 - 1.1e-05 25.0 0.3 3.7e-05 23.2 0.1 2.0 2 0 0 2 2 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.6 OAG18929.1 - 2.9e-05 24.0 0.1 0.00012 22.1 0.1 2.1 1 0 0 1 1 1 1 NAD(P)H-binding NodS PF05401.11 OAG18929.1 - 0.00021 21.0 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) RmlD_sub_bind PF04321.17 OAG18929.1 - 0.00046 19.4 0.1 0.0032 16.6 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short_C2 PF13561.6 OAG18929.1 - 0.001 18.7 0.0 0.068 12.7 0.0 2.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.24 OAG18929.1 - 0.0018 18.7 0.1 0.096 13.1 0.0 3.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG18929.1 - 0.0062 15.6 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 OAG18929.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 OAG18929.1 - 0.01 16.8 0.0 0.029 15.3 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 OAG18931.1 - 5.9e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG18931.1 - 1.3e-05 25.0 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG18931.1 - 0.14 12.1 0.2 11 6.0 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Zn_clus PF00172.18 OAG18932.1 - 6.7e-05 22.9 11.2 0.00011 22.2 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG18933.1 - 4.7e-18 65.2 0.0 9e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18933.1 - 7.9e-08 32.3 7.4 7.9e-08 32.3 7.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIF_OSM PF01291.17 OAG18933.1 - 0.026 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family MFS_1 PF07690.16 OAG18934.1 - 1.7e-47 162.0 33.0 1.7e-47 162.0 33.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18934.1 - 2.1e-15 56.6 21.5 3e-15 56.1 21.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG18934.1 - 9.1e-06 24.4 2.6 1.5e-05 23.7 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAG18934.1 - 0.1 10.9 5.9 0.83 8.0 5.9 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector DUF1772 PF08592.11 OAG18934.1 - 0.51 10.7 0.0 0.51 10.7 0.0 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) OATP PF03137.20 OAG18934.1 - 0.71 8.1 18.7 0.11 10.8 5.6 3.9 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 OAG18935.1 - 3.1e-21 75.9 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG18935.1 - 3.8e-07 29.7 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3037 PF11236.8 OAG18938.1 - 0.018 15.5 0.2 0.21 12.0 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3037) Nramp PF01566.18 OAG18939.1 - 3.4e-91 305.9 15.6 3.4e-91 305.9 15.6 1.9 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.21 OAG18940.1 - 6.2e-46 156.2 15.1 7.7e-46 155.8 15.1 1.0 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 OAG18940.1 - 0.0017 18.6 5.3 0.026 14.9 0.0 3.5 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 OAG18940.1 - 0.0033 17.8 11.3 0.066 13.7 1.3 3.3 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 OAG18940.1 - 0.0071 16.1 11.9 0.11 12.3 11.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF848 PF05852.11 OAG18940.1 - 0.014 15.5 3.1 0.014 15.5 3.1 2.0 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HSDR_N PF04313.14 OAG18940.1 - 0.029 14.3 2.1 0.032 14.2 1.1 1.5 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) FlaC_arch PF05377.11 OAG18940.1 - 0.035 14.5 5.8 3.5 8.1 0.1 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 OAG18940.1 - 0.054 13.4 11.9 0.075 13.0 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit Allexi_40kDa PF05549.11 OAG18940.1 - 0.1 12.1 2.6 0.58 9.6 0.2 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Nup88 PF10168.9 OAG18940.1 - 0.13 10.0 6.8 0.17 9.7 6.8 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF948 PF06103.11 OAG18940.1 - 0.14 12.4 1.9 1.1 9.6 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 OAG18940.1 - 0.16 12.2 13.7 0.89 9.8 7.7 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein BORCS7 PF16088.5 OAG18940.1 - 0.17 12.1 4.9 0.082 13.2 1.4 2.2 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Cob_adeno_trans PF01923.18 OAG18940.1 - 0.48 10.6 5.2 8.2 6.5 0.4 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Atg14 PF10186.9 OAG18940.1 - 0.52 9.4 8.7 0.94 8.5 8.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 OAG18940.1 - 0.53 9.6 10.8 0.93 8.8 10.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OAG18940.1 - 0.55 8.8 10.2 1.9 7.0 7.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A GrpE PF01025.19 OAG18940.1 - 0.87 9.2 9.3 1.5 8.5 7.8 2.0 1 1 1 2 2 2 0 GrpE BshC PF10079.9 OAG18940.1 - 1.1 7.9 8.9 1.5 7.5 8.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC FadA PF09403.10 OAG18940.1 - 1.5 9.4 11.9 1.1 9.8 7.2 2.3 1 1 1 2 2 2 0 Adhesion protein FadA Muted PF14942.6 OAG18940.1 - 2.3 8.5 10.2 6.6 7.1 5.8 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ABC_tran_CTD PF16326.5 OAG18940.1 - 3.2 8.1 12.0 0.74 10.1 0.4 3.4 1 1 2 3 3 3 0 ABC transporter C-terminal domain SAPS PF04499.15 OAG18941.1 - 2.9e-191 636.5 0.3 9.4e-191 634.8 0.1 2.0 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Arm PF00514.23 OAG18941.1 - 0.022 14.8 0.0 6.7 6.9 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SnoaL_2 PF12680.7 OAG18942.1 - 0.094 13.4 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Hexapep PF00132.24 OAG18943.1 - 1.5e-08 34.0 12.7 0.00065 19.3 3.8 4.4 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG18943.1 - 9e-07 28.6 11.5 0.042 13.6 0.1 3.9 3 2 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase zf-RING_2 PF13639.6 OAG18944.1 - 8.1e-06 26.1 16.4 2.8e-05 24.3 9.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAG18944.1 - 0.00032 20.9 7.0 0.00032 20.9 7.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain DUF1272 PF06906.11 OAG18944.1 - 0.0049 16.9 4.3 0.0049 16.9 4.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 OAG18944.1 - 0.077 12.8 12.1 0.22 11.3 6.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OAG18944.1 - 0.15 12.1 5.5 0.13 12.3 2.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG18944.1 - 1.4 8.8 15.1 1.2 9.0 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG18944.1 - 2 8.3 17.7 3.2 7.7 11.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG18944.1 - 2.7 7.9 14.4 7.8 6.4 8.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CitMHS PF03600.16 OAG18946.1 - 1.2e-16 60.8 0.0 2.9e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Citrate transporter Fungal_trans PF04082.18 OAG18947.1 - 7.3e-13 48.2 0.2 1.6e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG18947.1 - 1.9e-08 34.3 10.1 3.2e-08 33.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2264 PF10022.9 OAG18948.1 - 6.4e-134 446.5 1.6 7.9e-134 446.2 1.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) IlvN PF07991.12 OAG18949.1 - 7.5e-45 152.5 0.1 1.3e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAG18949.1 - 1.3e-39 135.8 0.0 2e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 OAG18949.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UQ_con PF00179.26 OAG18950.1 - 2.7e-39 134.0 0.0 3.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RibD_C PF01872.17 OAG18951.1 - 2.3e-33 115.8 0.0 2.7e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF218 PF02698.17 OAG18952.1 - 6.7e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Chitin_synth_1 PF01644.17 OAG18953.1 - 3.8e-68 228.6 0.0 5.7e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG18953.1 - 6.2e-29 99.8 0.0 1.8e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG18953.1 - 9.6e-24 83.9 0.0 6.2e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG18953.1 - 1.3e-08 35.0 4.5 1.3e-08 35.0 4.5 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF2070 PF09843.9 OAG18953.1 - 0.099 10.9 10.6 0.13 10.5 10.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MAD PF05557.13 OAG18954.1 - 2.3e-05 23.0 6.8 2.8e-05 22.7 6.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Taxilin PF09728.9 OAG18954.1 - 0.0027 17.0 6.6 0.004 16.4 6.6 1.3 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF3498 PF12004.8 OAG18954.1 - 0.024 13.9 6.7 0.028 13.6 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) SIR2 PF02146.17 OAG18954.1 - 0.095 12.6 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Sir2 family DUF3287 PF11690.8 OAG18954.1 - 0.97 9.2 5.6 12 5.7 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) PEPCK_ATP PF01293.20 OAG18956.1 - 3.1e-218 725.1 0.0 3.7e-218 724.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 OAG18956.1 - 0.13 12.4 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 OAG18957.1 - 2.6e-84 281.9 51.5 6.8e-47 159.6 20.4 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG18957.1 - 8.9e-35 120.2 0.2 4.9e-16 59.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 OAG18957.1 - 2.4e-34 117.1 2.8 2e-27 94.9 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG18957.1 - 2.6e-12 47.2 0.1 1.5e-11 44.7 0.1 2.5 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG18957.1 - 1.9e-08 33.8 48.9 3.3e-06 26.5 22.9 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 OAG18957.1 - 1.2e-05 25.7 0.1 0.0012 19.3 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG18957.1 - 1.6e-05 24.9 0.0 0.0003 20.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAG18957.1 - 7e-05 22.5 0.3 0.0073 15.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG18957.1 - 0.00014 21.8 0.0 0.63 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG18957.1 - 0.0018 18.0 0.3 0.19 11.5 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG18957.1 - 0.0025 18.1 0.4 0.084 13.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG18957.1 - 0.005 17.4 0.0 0.14 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG18957.1 - 0.0051 16.9 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG18957.1 - 0.0088 16.3 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG18957.1 - 0.0089 16.2 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG18957.1 - 0.023 14.3 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 OAG18957.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase NACHT PF05729.12 OAG18957.1 - 0.034 14.1 0.2 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 OAG18957.1 - 0.091 12.5 0.5 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG18957.1 - 0.12 12.8 6.5 0.14 12.6 0.0 3.1 4 0 0 4 4 2 0 AAA domain SMC_N PF02463.19 OAG18957.1 - 0.28 10.6 3.9 6 6.2 0.0 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG18957.1 - 0.32 11.5 7.4 0.64 10.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhnG PF06754.12 OAG18957.1 - 0.57 10.1 2.6 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Caveolin PF01146.17 OAG18957.1 - 0.69 9.9 5.0 1.8 8.5 5.0 1.7 1 0 0 1 1 1 0 Caveolin Peptidase_M20 PF01546.28 OAG18958.1 - 3.1e-32 112.0 0.0 5.1e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG18958.1 - 5.6e-11 42.3 0.0 1.4e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG18958.1 - 0.00026 20.7 0.1 0.0065 16.2 0.0 2.8 3 1 0 3 3 3 1 Peptidase family M28 MFS_1 PF07690.16 OAG18959.1 - 6.7e-32 110.8 20.5 1e-31 110.2 20.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG18959.1 - 7.2e-07 28.4 15.7 3.4e-06 26.2 15.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter E2F_TDP PF02319.20 OAG18960.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain zf-CCCH PF00642.24 OAG18962.1 - 1.5 8.9 3.4 8 6.5 3.4 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Spc7 PF08317.11 OAG18963.1 - 0.00045 19.2 13.0 0.00076 18.5 13.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Lebercilin PF15619.6 OAG18963.1 - 0.005 16.5 16.4 0.0079 15.9 16.4 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 OAG18963.1 - 0.0053 16.6 11.6 0.0091 15.8 11.6 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 OAG18963.1 - 0.0096 16.0 8.2 0.96 9.5 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) ZapB PF06005.12 OAG18963.1 - 0.011 16.1 19.9 0.025 15.0 2.5 3.5 1 1 2 3 3 3 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 OAG18963.1 - 0.013 15.1 1.2 0.013 15.1 1.2 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KASH_CCD PF14662.6 OAG18963.1 - 0.014 15.3 5.2 0.014 15.3 5.2 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH EzrA PF06160.12 OAG18963.1 - 0.016 13.4 10.5 0.022 12.9 10.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 OAG18963.1 - 0.046 13.8 17.7 0.85 9.8 1.1 3.6 3 0 0 3 3 3 0 bZIP transcription factor FUSC PF04632.12 OAG18963.1 - 0.051 12.1 1.0 0.071 11.6 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TetR_C_6 PF13977.6 OAG18963.1 - 0.055 13.7 0.2 0.56 10.5 0.2 2.3 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF4944 PF16302.5 OAG18963.1 - 0.13 12.4 1.6 0.2 11.7 0.7 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4944) DUF4407 PF14362.6 OAG18963.1 - 0.16 11.3 4.0 0.28 10.5 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 OAG18963.1 - 0.18 12.3 6.8 0.34 11.4 6.4 1.7 1 1 0 1 1 1 0 Spectrin repeat SHE3 PF17078.5 OAG18963.1 - 0.21 11.3 11.5 0.93 9.2 11.5 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 OAG18963.1 - 0.21 11.8 20.3 8.2 6.6 19.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 OAG18963.1 - 0.37 10.8 6.5 0.64 10.0 5.7 1.9 1 1 0 1 1 1 0 Laminin Domain II Leu_zip PF15294.6 OAG18963.1 - 0.42 10.1 15.4 6.1 6.3 15.6 2.1 1 1 0 1 1 1 0 Leucine zipper Prominin PF05478.11 OAG18963.1 - 0.53 8.2 3.0 0.72 7.7 3.0 1.1 1 0 0 1 1 1 0 Prominin Fez1 PF06818.15 OAG18963.1 - 0.62 10.5 14.9 1.2 9.6 14.9 1.4 1 0 0 1 1 1 0 Fez1 JIP_LZII PF16471.5 OAG18963.1 - 0.64 10.2 18.1 0.033 14.3 3.8 2.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF745 PF05335.13 OAG18963.1 - 0.69 9.6 8.4 1.1 8.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Macoilin PF09726.9 OAG18963.1 - 0.76 8.3 12.1 0.99 7.9 12.1 1.1 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 OAG18963.1 - 0.84 9.5 12.0 2.4 8.0 0.2 3.3 1 1 2 3 3 3 0 Septum formation initiator HIP1_clath_bdg PF16515.5 OAG18963.1 - 1 10.0 16.2 0.61 10.7 5.2 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 OAG18963.1 - 1.5 8.9 7.4 0.58 10.3 0.8 2.8 1 1 0 2 2 2 0 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 OAG18963.1 - 1.6 8.8 22.4 3.7 7.6 22.0 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 OAG18963.1 - 1.7 9.4 13.6 20 5.9 9.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Herpes_UL6 PF01763.16 OAG18963.1 - 1.7 7.1 4.9 0.69 8.4 2.0 1.6 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF4200 PF13863.6 OAG18963.1 - 1.9 8.9 18.5 0.085 13.3 4.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 OAG18963.1 - 2.2 6.8 10.7 2.8 6.5 9.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Yuri_gagarin PF15934.5 OAG18963.1 - 2.4 7.9 13.5 16 5.3 13.5 2.0 1 1 0 1 1 1 0 Yuri gagarin Golgin_A5 PF09787.9 OAG18963.1 - 2.5 7.5 15.0 14 5.0 14.8 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 OAG18963.1 - 3.2 7.8 16.6 31 4.7 11.4 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 OAG18963.1 - 3.3 8.1 17.4 2.9 8.3 3.2 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 OAG18963.1 - 3.3 7.0 16.5 1.1 8.6 10.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 OAG18963.1 - 4.4 6.6 12.1 3.8 6.9 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) OmpH PF03938.14 OAG18963.1 - 5.3 7.4 11.3 11 6.3 11.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.13 OAG18963.1 - 6 7.4 12.9 0.84 10.2 7.4 2.5 3 0 0 3 3 1 0 HSCB C-terminal oligomerisation domain bZIP_2 PF07716.15 OAG18963.1 - 6.3 7.0 17.0 29 4.8 0.1 3.7 2 1 0 3 3 3 0 Basic region leucine zipper BRE1 PF08647.11 OAG18963.1 - 6.5 6.9 15.6 4.5 7.4 3.9 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4140 PF13600.6 OAG18963.1 - 6.7 7.2 19.1 7.6 7.0 1.1 4.1 2 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 OAG18963.1 - 6.9 7.3 8.4 53 4.5 7.2 2.8 1 1 1 2 2 1 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 OAG18963.1 - 8.4 4.2 6.4 15 3.3 6.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 OAG18963.1 - 9.8 5.9 13.3 36 4.1 13.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Acid_PPase PF12689.7 OAG18964.1 - 6e-66 221.4 0.0 7.3e-66 221.2 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Zn_clus PF00172.18 OAG18965.1 - 3e-06 27.2 9.0 3e-06 27.2 9.0 3.3 4 0 0 4 4 4 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG18965.1 - 1.8 9.2 7.3 0.14 12.7 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.25 OAG18966.1 - 2.9e-20 72.6 0.1 3.7e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG18966.1 - 5.7e-19 68.6 0.0 8.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG18966.1 - 3.5e-13 49.8 0.0 5.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG18966.1 - 0.00019 20.7 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG18966.1 - 0.068 12.6 0.1 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 OAG18967.1 - 6.5e-10 38.8 0.1 1.5e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG18967.1 - 0.00049 19.9 0.1 0.0014 18.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain DNA_photolyase PF00875.18 OAG18967.1 - 0.09 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 DNA photolyase TFA2_Winged_2 PF18121.1 OAG18968.1 - 8.8e-15 54.1 0.1 2.6e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAG18968.1 - 3.4e-14 52.9 0.3 8.4e-14 51.6 0.1 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain Sulfatase PF00884.23 OAG18969.1 - 1.8e-56 191.8 0.3 3.6e-56 190.8 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Choline_sulf_C PF12411.8 OAG18969.1 - 1.5e-22 79.1 1.6 3.8e-22 77.8 0.3 2.3 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 OAG18969.1 - 8.2e-06 25.6 0.1 0.0002 21.1 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAG18969.1 - 0.0015 18.8 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 OAG18969.1 - 0.012 16.4 0.0 0.037 14.7 0.0 1.9 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase UQ_con PF00179.26 OAG18970.1 - 1.2e-51 174.0 0.0 1.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG18970.1 - 0.0024 17.6 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG18970.1 - 0.054 13.8 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain TRI12 PF06609.13 OAG18972.1 - 3.5e-18 65.4 21.9 4.9e-18 64.9 21.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG18972.1 - 5.9e-11 41.9 58.3 6e-11 41.9 53.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 OAG18972.1 - 0.012 15.6 1.9 0.012 15.6 1.9 5.5 5 1 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III PCRF PF03462.18 OAG18973.1 - 3.4e-51 173.9 0.0 9.4e-51 172.4 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAG18973.1 - 1.7e-34 118.2 3.2 4.4e-34 116.9 3.2 1.7 1 0 0 1 1 1 1 RF-1 domain G_glu_transpept PF01019.21 OAG18974.1 - 6.6e-142 473.9 0.0 9.5e-142 473.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3602 PF12223.8 OAG18976.1 - 0.13 12.8 0.4 0.13 12.8 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3602) HECT PF00632.25 OAG18977.1 - 6.5e-68 229.5 0.0 1.8e-67 228.0 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OAG18977.1 - 1.3e-18 67.0 1.7 2.8e-18 65.9 1.0 2.0 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 OAG18978.1 - 4.6e-32 110.4 11.4 4.1e-26 91.3 3.4 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAG18978.1 - 9.3e-08 32.2 4.3 1.6e-06 28.3 2.2 4.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG18978.1 - 1e-06 28.9 8.2 1.5e-05 25.2 2.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG18978.1 - 0.0091 16.8 19.6 1.5 9.9 0.3 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG18978.1 - 0.03 14.8 0.4 0.03 14.8 0.4 5.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type GAGA PF09237.11 OAG18978.1 - 2.2 8.2 4.4 0.88 9.4 0.3 2.3 2 0 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.6 OAG18978.1 - 2.6 8.1 10.1 9.1 6.4 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger HET PF06985.11 OAG18979.1 - 1.5e-31 109.7 0.5 2.8e-31 108.8 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rif1_N PF12231.8 OAG18980.1 - 4e-109 365.1 4.0 6.8e-109 364.3 4.0 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 OAG18981.1 - 1.9e-121 406.3 0.5 2.2e-121 406.1 0.5 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Phage_TAC_12 PF12363.8 OAG18981.1 - 0.056 13.9 0.3 9.3 6.7 0.0 3.6 4 0 0 4 4 4 0 Phage tail assembly chaperone protein, TAC FAM178 PF14816.6 OAG18981.1 - 0.078 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function, FAM178 Tht1 PF04163.12 OAG18982.1 - 1.3e-05 24.2 10.3 5.7e-05 22.1 0.4 2.2 1 1 1 2 2 2 2 Tht1-like nuclear fusion protein DUF948 PF06103.11 OAG18982.1 - 0.012 15.9 4.0 0.15 12.4 0.6 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 OAG18982.1 - 0.024 14.4 2.3 6.1 6.7 0.2 3.0 3 0 0 3 3 3 0 Synaptobrevin Latarcin PF10279.9 OAG18982.1 - 0.049 14.0 0.3 0.11 13.0 0.3 1.6 1 0 0 1 1 1 0 Latarcin precursor LpqV PF17301.2 OAG18982.1 - 0.099 12.9 0.5 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 Putative lipoprotein LpqV TCTP PF00838.17 OAG18982.1 - 0.18 12.1 2.3 0.32 11.3 2.0 1.5 1 1 0 1 1 1 0 Translationally controlled tumour protein Phasin PF05597.11 OAG18982.1 - 0.38 10.8 5.7 0.15 12.0 1.7 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 OAG18982.1 - 2.7 8.0 6.2 0.83 9.7 1.5 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 OAG18982.1 - 8 5.9 11.4 16 4.9 11.4 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 OAG18982.1 - 9.1 5.3 11.9 1.4e+02 1.3 11.2 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L6 PF00347.23 OAG18983.1 - 1.3e-22 80.2 0.0 3.3e-11 43.7 0.0 3.3 2 2 1 3 3 3 2 Ribosomal protein L6 FAD_binding_4 PF01565.23 OAG18985.1 - 2.9e-23 82.1 2.8 3.4e-23 81.9 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG18985.1 - 0.05 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF1493 PF07377.12 OAG18987.1 - 0.019 15.4 0.2 0.073 13.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HET PF06985.11 OAG18988.1 - 2.2e-24 86.5 2.0 3.2e-24 85.9 2.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 OAG18989.1 - 1.8e-63 214.4 0.1 4.6e-62 209.8 0.1 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG18989.1 - 1.4e-17 64.0 0.1 5.1e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG18989.1 - 1.7e-05 24.9 0.0 7.2e-05 22.8 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 OAG18990.1 - 4.8e-22 78.4 53.6 1.3e-19 70.4 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.7 OAG18990.1 - 4.7e-14 52.4 0.2 9e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG18990.1 - 3.8e-10 39.9 0.0 5.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.18 OAG18991.1 - 2e-08 34.2 8.0 5.1e-08 32.9 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.25 OAG18992.1 - 1.3e-27 96.4 0.0 2.1e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAG18992.1 - 1.8e-05 24.1 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG18992.1 - 0.0049 17.5 0.9 0.015 15.9 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG18992.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAG18992.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 OAG18992.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 OAG18993.1 - 6.5e-30 104.2 38.5 9.6e-30 103.7 35.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG18993.1 - 3.2e-13 49.0 5.7 5.9e-13 48.1 5.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG18993.1 - 5.3e-07 28.9 9.0 5.3e-07 28.9 9.0 3.8 2 1 1 3 3 3 1 Sugar (and other) transporter F-box-like PF12937.7 OAG18994.1 - 8.1e-07 28.8 0.6 1.6e-06 27.9 0.6 1.5 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.21 OAG18995.1 - 2.4e-36 125.7 0.0 3.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG18995.1 - 0.03 12.9 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 OAG18996.1 - 2.5e-55 186.9 1.0 3.6e-55 186.3 1.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG18996.1 - 2.2e-14 53.8 0.0 4.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OAG18996.1 - 0.059 13.6 0.2 0.23 11.8 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 OAG18997.1 - 1.6e-69 234.6 0.0 2.3e-48 165.0 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.12 OAG18997.1 - 1.1e-10 42.2 0.3 5.4e-10 39.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG18997.1 - 3.5e-09 37.3 0.5 5e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 OAG18997.1 - 1.3e-06 28.2 0.8 9.5e-06 25.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG18997.1 - 1.7e-05 25.3 0.3 0.0002 21.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG18997.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.6 OAG18997.1 - 0.0046 15.8 0.2 0.0046 15.8 0.2 1.9 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.17 OAG18997.1 - 0.024 13.8 0.0 0.062 12.5 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 OAG18997.1 - 0.058 12.3 0.1 0.086 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 OAG18997.1 - 0.071 12.4 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DDRGK PF09756.9 OAG18997.1 - 0.13 11.9 9.5 0.17 11.4 1.5 2.3 2 0 0 2 2 2 0 DDRGK domain DUF3391 PF11871.8 OAG18997.1 - 2.4 8.7 7.4 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PEX11 PF05648.14 OAG18998.1 - 1.8e-70 236.9 0.3 2.1e-70 236.7 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) zf-XS PF03470.14 OAG18998.1 - 0.045 14.0 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 XS zinc finger domain p450 PF00067.22 OAG18999.1 - 1.7e-64 218.3 0.0 2.3e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG19001.1 - 2.2e-26 92.7 22.7 1.7e-16 60.1 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG19001.1 - 2.1e-14 53.2 37.8 2.1e-14 53.2 37.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 OAG19001.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.4 4 0 0 4 4 4 0 Phospholipid methyltransferase Med3 PF11593.8 OAG19002.1 - 0.95 8.6 6.0 1.1 8.4 6.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2894 PF11445.8 OAG19003.1 - 0.24 11.8 3.6 0.39 11.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cellulase PF00150.18 OAG19004.1 - 1.7e-16 60.5 1.3 1.7e-16 60.5 1.3 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UPF0258 PF06789.12 OAG19004.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) TMEM154 PF15102.6 OAG19004.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.10 OAG19004.1 - 0.23 11.5 1.5 0.57 10.3 0.4 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) OapA_N PF08525.11 OAG19004.1 - 5.3 7.1 6.1 8.5 6.5 6.1 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif CTP_transf_like PF01467.26 OAG19005.1 - 9.9e-24 84.2 0.0 1.3e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HECT PF00632.25 OAG19006.1 - 1.3e-81 274.4 0.0 3.7e-81 272.9 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT_EZ PF13513.6 OAG19006.1 - 0.0046 17.4 0.0 0.32 11.6 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 OAG19006.1 - 0.016 13.8 1.0 2 6.9 0.0 2.9 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 OAG19006.1 - 0.062 13.6 0.5 27 5.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Wap1 PF16997.5 OAG19006.1 - 0.082 12.0 0.0 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Wap1 domain HET PF06985.11 OAG19007.1 - 6.9e-28 97.8 4.7 1e-26 94.1 4.7 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ivy PF08816.11 OAG19007.1 - 0.092 12.9 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) Isochorismatase PF00857.20 OAG19009.1 - 4.5e-44 150.7 0.0 5.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1771 PF08590.10 OAG19010.1 - 1.5e-06 28.4 7.3 3.5e-06 27.3 7.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAG19010.1 - 0.00023 21.5 0.0 0.00056 20.2 0.0 1.7 1 0 0 1 1 1 1 Smr domain SARAF PF06682.12 OAG19011.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4719 PF15843.5 OAG19011.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Shisa PF13908.6 OAG19011.1 - 0.026 14.8 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OAG19011.1 - 0.14 13.1 0.2 0.26 12.2 0.2 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM100 PF16311.5 OAG19011.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 DUF5426 PF17473.2 OAG19011.1 - 0.17 12.1 0.5 0.25 11.6 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5426) F-box-like PF12937.7 OAG19012.1 - 2.4e-09 36.9 1.9 4.4e-08 32.9 0.4 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG19012.1 - 0.0083 16.0 1.8 0.0083 16.0 1.8 2.4 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAG19012.1 - 0.14 12.0 0.3 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 F-box Pro_Al_protease PF02983.14 OAG19012.1 - 0.2 11.7 0.2 25 5.0 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain zf-CCHC PF00098.23 OAG19014.1 - 5e-05 23.2 1.7 0.00018 21.4 1.7 2.1 1 0 0 1 1 1 1 Zinc knuckle HypA PF01155.19 OAG19014.1 - 0.23 11.5 3.7 1.1 9.3 2.8 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Abhydrolase_6 PF12697.7 OAG19015.1 - 0.00021 21.9 2.4 0.00027 21.6 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG19015.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG19015.1 - 0.023 13.6 0.4 0.15 11.0 0.4 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG19015.1 - 0.19 11.0 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1100 PF06500.11 OAG19016.1 - 2.3e-13 49.7 0.0 3.9e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 OAG19016.1 - 5.1e-05 22.8 0.1 0.00013 21.5 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG19016.1 - 0.015 16.0 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG19016.1 - 0.027 14.1 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold D5_N PF08706.11 OAG19016.1 - 0.028 14.7 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 D5 N terminal like BAAT_C PF08840.11 OAG19016.1 - 0.048 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 OAG19016.1 - 0.052 13.1 0.1 0.18 11.3 0.1 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 OAG19016.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 F-box PF00646.33 OAG19018.1 - 0.0047 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain DNA_pol_A_exo1 PF01612.20 OAG19019.1 - 0.0041 16.9 0.1 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease Zn_Tnp_IS1595 PF12760.7 OAG19019.1 - 7.9 6.5 11.4 1.1 9.2 6.8 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PTR2 PF00854.21 OAG19020.1 - 6.7e-87 291.9 11.5 9.8e-87 291.3 11.5 1.2 1 0 0 1 1 1 1 POT family Peptidase_M20 PF01546.28 OAG19022.1 - 5.2e-25 88.4 0.0 2.3e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 OAG19022.1 - 7.5e-12 45.6 7.1 0.014 16.3 1.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 OAG19022.1 - 8.5e-07 28.9 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG19022.1 - 0.0002 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ANAPC4_WD40 PF12894.7 OAG19022.1 - 0.0095 16.2 0.0 0.18 12.2 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG19022.1 - 0.21 10.9 0.0 18 4.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain TraQ PF09679.10 OAG19023.1 - 0.18 11.7 1.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) adh_short PF00106.25 OAG19024.1 - 3.1e-36 124.7 0.0 4e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19024.1 - 1.3e-32 113.3 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19024.1 - 7.9e-08 32.4 0.1 1.4e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OAG19024.1 - 0.13 12.7 0.3 0.28 11.6 0.3 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.15 OAG19024.1 - 1.4 8.7 3.6 27 4.5 3.6 2.2 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 OAG19025.1 - 1e-34 120.0 18.3 1e-34 120.0 18.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 OAG19025.1 - 0.03 13.9 0.5 0.03 13.9 0.5 3.2 4 1 0 4 4 4 0 ABC-2 family transporter protein Phage_holin_5_2 PF16079.5 OAG19025.1 - 0.16 12.4 0.3 0.16 12.4 0.3 4.1 4 2 1 5 5 5 0 Phage holin family Hol44, in holin superfamily V Sugar_tr PF00083.24 OAG19027.1 - 1.4e-97 327.4 15.1 1.7e-97 327.2 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19027.1 - 4.1e-26 91.8 11.8 4.1e-26 91.8 11.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily SDA1 PF05285.12 OAG19029.1 - 0.65 9.4 4.1 0.79 9.1 4.1 1.1 1 0 0 1 1 1 0 SDA1 COX15-CtaA PF02628.15 OAG19030.1 - 5.4e-110 367.5 9.4 6.6e-110 367.2 9.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Amj PF10997.8 OAG19030.1 - 0.0063 15.9 0.3 0.64 9.3 0.0 2.4 2 0 0 2 2 2 2 Alternate to MurJ DUF21 PF01595.20 OAG19030.1 - 0.071 12.8 2.2 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain BTB PF00651.31 OAG19031.1 - 0.00056 20.1 0.0 0.00096 19.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Na_H_Exchanger PF00999.21 OAG19032.1 - 1.1e-61 208.8 24.1 1.4e-61 208.4 24.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ORMDL PF04061.14 OAG19033.1 - 2e-57 192.8 1.0 2.4e-57 192.5 1.0 1.0 1 0 0 1 1 1 1 ORMDL family Ino80_Iec3 PF14612.6 OAG19034.1 - 1.6e-75 254.9 4.4 2.2e-75 254.4 4.4 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling MRP-S28 PF10213.9 OAG19035.1 - 6.7e-44 149.4 0.0 1.1e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 OAG19036.1 - 6.2e-17 62.1 0.0 9.3e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 OAG19036.1 - 0.03 13.6 0.0 0.065 12.5 0.0 1.4 1 1 1 2 2 2 0 Glycosyl transferase family 1 UDPGT PF00201.18 OAG19036.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Cellulase PF00150.18 OAG19037.1 - 4.5e-18 65.7 1.0 4.5e-18 65.7 1.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 OAG19037.1 - 0.0023 17.4 0.1 0.0055 16.1 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase F-box PF00646.33 OAG19038.1 - 0.057 13.3 0.1 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 F-box domain Tyrosinase PF00264.20 OAG19040.1 - 8.4e-52 176.6 0.2 2.5e-51 175.1 0.0 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF3493 PF11998.8 OAG19041.1 - 3.8 7.8 7.0 17 5.6 0.9 3.1 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 SH3_1 PF00018.28 OAG19042.1 - 1.1e-14 53.7 0.1 1.6e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG19042.1 - 5.5e-10 38.9 0.0 8.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG19042.1 - 3.5e-08 33.0 0.0 5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain Myc_target_1 PF15179.6 OAG19042.1 - 3.3 7.6 5.3 2.4 8.0 1.2 2.0 2 0 0 2 2 2 0 Myc target protein 1 adh_short PF00106.25 OAG19043.1 - 6.6e-37 126.9 0.0 9.1e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19043.1 - 9.7e-22 77.7 0.0 1.2e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19043.1 - 3.9e-07 30.2 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG19043.1 - 0.00053 19.5 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG19043.1 - 0.00055 19.9 0.0 0.00079 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG19043.1 - 0.00095 19.4 0.1 0.0019 18.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 OAG19043.1 - 0.0046 17.5 0.0 0.0076 16.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAG19043.1 - 0.012 15.1 0.1 0.031 13.8 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG19043.1 - 0.028 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OAG19043.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RGS PF00615.19 OAG19044.1 - 0.0015 18.8 0.1 0.007 16.6 0.1 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2721 PF11026.8 OAG19044.1 - 0.0021 18.0 0.3 2.9 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2721) ATP_bind_3 PF01171.20 OAG19045.1 - 2.2e-17 63.4 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 OAG19045.1 - 4.7e-17 61.2 4.9 4.7e-17 61.2 4.9 3.5 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 OAG19045.1 - 0.0022 17.5 0.9 0.0022 17.5 0.9 3.3 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 OAG19045.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 OAG19045.1 - 1 9.6 5.6 1.6 8.9 0.5 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.26 OAG19046.1 - 6.7e-151 503.4 12.4 8.8e-151 503.0 12.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG19046.1 - 2e-38 131.2 0.0 3.6e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG19046.1 - 1.3e-10 41.5 0.3 1.3e-10 41.5 0.3 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like zf-C2H2_4 PF13894.6 OAG19048.1 - 1.4e-05 25.5 2.6 0.00085 20.0 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG19048.1 - 5.1e-05 22.9 4.8 0.089 12.6 0.1 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 OAG19048.1 - 0.0008 19.7 11.0 0.0063 16.9 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 OAG19048.1 - 0.0044 17.3 0.1 0.0044 17.3 0.1 2.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PhnA_Zn_Ribbon PF08274.12 OAG19048.1 - 0.021 14.8 2.2 0.18 11.8 0.4 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-H2C2_5 PF13909.6 OAG19048.1 - 0.06 13.1 5.3 0.14 12.0 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zinc-ribbons_6 PF07191.12 OAG19048.1 - 0.18 11.8 9.8 1.7 8.7 3.5 2.4 1 1 1 2 2 2 0 zinc-ribbons DpnI PF06044.12 OAG19048.1 - 0.61 9.7 6.0 1.2 8.7 3.5 2.0 1 1 1 2 2 2 0 Dam-replacing family C1_4 PF07975.12 OAG19048.1 - 7.7 6.8 9.1 2.4 8.4 5.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain adh_short PF00106.25 OAG19049.1 - 5.4e-17 61.9 0.0 7.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19049.1 - 3.2e-11 43.2 0.0 7.9e-11 42.0 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19049.1 - 1e-09 38.6 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19049.1 - 0.081 12.4 0.1 2.5 7.5 0.0 2.3 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG19049.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Dynamin_N PF00350.23 OAG19050.1 - 1.7e-05 24.9 1.3 8.4e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 Dynamin family IIGP PF05049.13 OAG19050.1 - 0.00075 18.7 0.1 0.0024 17.0 0.1 1.8 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 OAG19050.1 - 0.0059 16.7 0.1 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG19050.1 - 0.0071 16.9 0.4 0.087 13.3 0.0 2.8 3 0 0 3 3 3 1 ABC transporter DUF4349 PF14257.6 OAG19050.1 - 0.0082 15.6 0.5 0.56 9.6 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) AIG1 PF04548.16 OAG19050.1 - 0.0089 15.4 0.2 0.0089 15.4 0.2 3.7 4 0 0 4 4 4 1 AIG1 family T2SSE PF00437.20 OAG19050.1 - 0.018 14.1 0.0 0.058 12.5 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAG19050.1 - 0.021 14.3 0.6 0.31 10.5 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_22 PF13401.6 OAG19050.1 - 0.089 13.1 0.2 1.2 9.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain GrlR PF16518.5 OAG19050.1 - 0.13 12.2 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 T3SS negative regulator,GrlR DUF4140 PF13600.6 OAG19050.1 - 0.23 11.9 2.9 3 8.3 0.1 3.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_16 PF13191.6 OAG19050.1 - 0.29 11.5 4.9 0.72 10.2 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain Fib_alpha PF08702.10 OAG19050.1 - 0.36 11.0 6.1 2.4 8.3 0.0 3.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF87 PF01935.17 OAG19050.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain Nbl1_Borealin_N PF10444.9 OAG19050.1 - 2.9 7.6 6.3 1.3 8.7 0.7 3.3 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Frankia_peptide PF14407.6 OAG19050.1 - 3.6 7.7 5.7 1.5 8.8 0.1 3.5 4 0 0 4 4 4 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Spore_III_AB PF09548.10 OAG19050.1 - 5.5 7.1 7.4 1.3 9.1 0.1 3.2 5 0 0 5 5 4 0 Stage III sporulation protein AB (spore_III_AB) FlaC_arch PF05377.11 OAG19050.1 - 6.6 7.2 5.5 3.3 8.2 0.1 3.2 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) COesterase PF00135.28 OAG19051.1 - 1.8e-58 198.7 0.0 8.1e-58 196.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG19051.1 - 6.1e-05 23.0 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG19051.1 - 0.0013 18.2 0.3 0.0065 16.0 0.6 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG19051.1 - 0.0016 19.1 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 OAG19051.1 - 0.0073 15.4 0.0 0.015 14.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Say1_Mug180 PF10340.9 OAG19051.1 - 0.23 10.3 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Steryl acetyl hydrolase Peptidase_S8 PF00082.22 OAG19053.1 - 3.4e-30 105.3 9.2 1.8e-29 103.0 9.2 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG19053.1 - 0.059 14.0 0.1 0.64 10.7 0.1 2.1 1 1 0 1 1 1 0 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 OAG19054.1 - 2.9e-33 115.4 15.3 6.8e-33 114.2 15.3 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG19054.1 - 8.2e-06 26.4 0.1 7.9e-05 23.3 0.1 2.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 ig PF00047.25 OAG19055.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain HET PF06985.11 OAG19056.1 - 2.5e-29 102.5 0.1 3.5e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTZ PF03867.14 OAG19059.1 - 0.43 10.1 4.7 6.6 6.2 1.2 2.2 1 1 1 2 2 2 0 Fushi tarazu (FTZ), N-terminal region ATP-synt_DE PF00401.20 OAG19059.1 - 0.72 10.2 7.6 0.1 12.9 2.9 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain zf-CCCH PF00642.24 OAG19060.1 - 0.00035 20.4 39.1 0.00057 19.7 2.3 5.4 4 1 1 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG19060.1 - 0.00085 19.1 3.7 0.00085 19.1 3.7 5.5 5 1 0 5 5 5 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG19060.1 - 0.004 17.2 6.3 0.004 17.2 6.3 5.5 5 1 0 5 5 5 3 Zinc finger domain UPF0052 PF01933.18 OAG19060.1 - 0.034 13.4 0.1 0.076 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 zf-CCCH_3 PF15663.5 OAG19060.1 - 0.087 13.0 13.0 0.22 11.8 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger containing family Pex26 PF07163.12 OAG19060.1 - 0.78 9.0 0.0 0.78 9.0 0.0 2.6 2 1 0 2 2 2 0 Pex26 protein DUF4083 PF13314.6 OAG19060.1 - 0.85 9.6 3.6 4.6 7.3 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) Asp-B-Hydro_N PF05279.11 OAG19060.1 - 4.1 7.4 11.5 9.2 6.3 11.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fungal_trans PF04082.18 OAG19061.1 - 1.4e-20 73.5 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19061.1 - 0.0016 18.6 9.8 0.0033 17.5 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHO4 PF01384.20 OAG19062.1 - 1.6e-101 339.7 18.8 1.9e-101 339.5 18.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 OAG19062.1 - 4.3 7.7 10.0 1.4 9.2 0.4 3.1 2 1 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 RRM_1 PF00076.22 OAG19063.1 - 1.1e-05 25.2 0.0 0.0022 17.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nitroreductase PF00881.24 OAG19064.1 - 1.6e-14 54.3 0.0 2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Sugar_tr PF00083.24 OAG19065.1 - 4.7e-130 434.5 26.2 5.3e-130 434.3 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19065.1 - 7.2e-24 84.4 50.2 4.6e-22 78.4 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Orai-1 PF07856.12 OAG19065.1 - 0.69 9.6 0.0 0.69 9.6 0.0 2.7 3 1 0 3 3 3 0 Mediator of CRAC channel activity TMEM174 PF15029.6 OAG19066.1 - 0.56 9.9 1.6 0.73 9.5 1.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 174 Herpes_LMP2 PF07415.11 OAG19066.1 - 0.93 8.2 5.4 0.36 9.5 1.6 1.8 1 1 1 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein RRM_1 PF00076.22 OAG19067.1 - 1.9e-16 59.6 0.0 3.5e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG19067.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Bot1p PF12298.8 OAG19068.1 - 7.7e-54 182.4 1.3 1.8e-53 181.2 1.3 1.7 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein TMEM208_SND2 PF05620.11 OAG19069.1 - 8.6e-54 181.8 0.9 9.7e-54 181.6 0.9 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_2 PF07719.17 OAG19070.1 - 1.9e-38 127.5 24.8 3.6e-07 29.8 1.3 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG19070.1 - 4.2e-36 123.0 12.9 7.7e-23 80.5 1.4 5.7 4 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAG19070.1 - 2.9e-33 112.3 24.1 1.5e-07 30.9 0.0 9.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 OAG19070.1 - 1.2e-30 103.1 13.4 2.8e-05 24.0 0.3 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAG19070.1 - 2.4e-26 92.1 20.2 4.4e-08 33.6 1.6 8.4 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19070.1 - 3.8e-22 78.6 14.7 0.00012 22.5 0.3 8.0 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG19070.1 - 2e-21 76.1 15.4 2.9e-05 24.3 0.1 8.4 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG19070.1 - 4.8e-21 73.7 20.1 0.0013 19.4 0.0 10.4 8 1 3 11 11 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG19070.1 - 1.2e-19 69.2 7.8 0.43 11.1 0.2 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG19070.1 - 2.7e-18 65.3 18.8 9.3e-06 25.2 0.7 9.3 7 3 4 11 11 11 4 TPR repeat TPR_6 PF13174.6 OAG19070.1 - 1.7e-12 47.1 16.8 1.5 9.6 0.0 10.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG19070.1 - 4e-12 45.3 13.3 0.025 14.6 0.2 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAG19070.1 - 1.2e-08 34.9 13.5 0.028 14.5 0.2 6.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 OAG19070.1 - 9.8e-06 25.0 11.6 0.00027 20.2 2.7 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 OAG19070.1 - 0.00029 21.1 3.6 5.8 7.3 0.1 5.8 5 2 2 7 7 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAG19070.1 - 0.01 15.5 1.4 8 6.1 0.1 4.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 OAG19070.1 - 0.015 15.2 14.8 0.28 11.1 0.3 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 OAG19070.1 - 0.026 15.1 0.1 27 5.4 0.0 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4810) PPR PF01535.20 OAG19070.1 - 0.03 14.5 0.9 19 5.8 0.0 3.7 3 0 0 3 3 3 0 PPR repeat TOM20_plant PF06552.12 OAG19070.1 - 0.052 13.3 1.4 0.19 11.5 0.3 2.4 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 CCP_MauG PF03150.14 OAG19070.1 - 0.068 13.8 0.1 0.19 12.3 0.1 1.8 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase SRP_TPR_like PF17004.5 OAG19070.1 - 0.12 12.4 0.1 3.2 7.8 0.0 2.9 3 1 0 3 3 3 0 Putative TPR-like repeat FAT PF02259.23 OAG19070.1 - 0.12 11.5 2.9 1.1 8.4 1.2 2.7 2 1 0 2 2 2 0 FAT domain DUF5113 PF17140.4 OAG19070.1 - 0.16 11.7 3.3 4.2 7.1 1.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) Fis1_TPR_C PF14853.6 OAG19070.1 - 0.32 11.1 5.1 3.7 7.7 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 OAG19070.1 - 6.8 6.4 12.1 0.98 9.1 0.1 4.1 4 2 1 5 5 5 0 Tetratricopeptide repeat-like domain ADH_N PF08240.12 OAG19071.1 - 0.0018 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG19071.1 - 0.019 14.9 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Bac_luciferase PF00296.20 OAG19072.1 - 7.8e-58 196.4 0.1 1.1e-57 195.9 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMO-like PF00743.19 OAG19073.1 - 1.6e-16 59.9 0.1 4.8e-16 58.3 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG19073.1 - 5.4e-13 48.8 0.0 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG19073.1 - 8.7e-11 41.9 0.0 2.7e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG19073.1 - 6.8e-09 35.4 0.7 3.5e-08 33.1 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG19073.1 - 2e-05 23.9 0.0 0.0016 17.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG19073.1 - 2.7e-05 23.9 0.2 0.00024 20.8 0.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG19073.1 - 0.0014 18.7 0.3 0.4 10.7 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG19073.1 - 0.0038 17.8 0.2 1.4 9.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG19073.1 - 0.015 14.5 0.2 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 OAG19073.1 - 0.062 12.6 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Mqo PF06039.15 OAG19073.1 - 0.19 10.2 0.6 4.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.20 OAG19073.1 - 0.2 11.7 0.0 39 4.3 0.0 3.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 OAG19074.1 - 1.3e-07 30.9 27.9 1.3e-07 30.9 27.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG19074.1 - 1.4e-06 28.1 4.0 1.4e-06 28.1 4.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Tyrosinase PF00264.20 OAG19075.1 - 5.9e-38 131.4 0.0 7.7e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 OAG19075.1 - 0.2 12.3 0.0 0.36 11.5 0.0 1.3 1 0 0 1 1 1 0 HMG-box domain FAD_binding_6 PF00970.24 OAG19076.1 - 1.6e-31 108.6 0.0 2.2e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG19076.1 - 6.9e-29 100.7 0.0 1.1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG19076.1 - 1.8e-05 24.9 0.0 0.0041 17.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG19076.1 - 0.0054 16.9 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF1923 PF09083.10 OAG19076.1 - 0.048 13.4 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) HAP1_N PF04849.13 OAG19077.1 - 0.014 14.6 1.2 0.016 14.4 1.2 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region MCM3AP_GANP PF16769.5 OAG19077.1 - 0.35 9.1 0.6 0.37 9.0 0.6 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP zf-C3H1 PF10650.9 OAG19078.1 - 1.2e-12 47.3 2.2 1.9e-12 46.6 2.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DUF3450 PF11932.8 OAG19078.1 - 0.0073 15.6 3.1 0.018 14.3 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 OAG19078.1 - 0.02 13.8 4.3 0.059 12.2 4.3 1.7 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mod_r PF07200.13 OAG19078.1 - 0.096 12.8 8.4 0.033 14.3 4.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 OAG19078.1 - 0.46 11.1 9.3 0.18 12.4 4.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 OAG19078.1 - 5.5 5.8 9.6 13 4.6 9.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAG19078.1 - 6.3 6.9 8.2 7.2 6.7 6.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sod_Cu PF00080.20 OAG19079.1 - 6.2e-47 159.3 8.3 7.2e-47 159.1 8.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 OAG19080.1 - 2.1e-93 312.8 2.0 2.3e-93 312.7 2.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 OAG19080.1 - 0.051 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus adh_short PF00106.25 OAG19081.1 - 7.5e-36 123.4 0.0 1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19081.1 - 6.1e-27 94.7 0.0 2.2e-26 92.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19081.1 - 7e-05 22.8 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Acyltransferase PF01553.21 OAG19082.1 - 5.2e-32 110.3 0.0 8.2e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase 7tm_3 PF00003.22 OAG19083.1 - 0.00048 19.9 5.2 0.00086 19.1 0.7 2.1 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR EptA_B_N PF08019.12 OAG19083.1 - 0.028 14.3 3.9 0.19 11.6 0.5 2.8 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Tetraspanin PF00335.20 OAG19083.1 - 0.065 12.9 3.4 0.18 11.5 3.3 1.9 1 1 0 1 1 1 0 Tetraspanin family 5TM-5TMR_LYT PF07694.12 OAG19083.1 - 0.25 10.9 11.1 6.5 6.2 0.0 2.9 2 1 0 2 2 2 0 5TMR of 5TMR-LYT DUF1345 PF07077.11 OAG19083.1 - 1.2 8.8 8.1 0.79 9.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) RDD PF06271.12 OAG19083.1 - 1.9 8.7 9.0 3.3 7.9 2.4 2.9 3 0 0 3 3 3 0 RDD family FtsX PF02687.21 OAG19083.1 - 2 8.9 9.4 38 4.8 7.7 2.7 2 1 0 2 2 2 0 FtsX-like permease family Glyco_hydro_16 PF00722.21 OAG19086.1 - 1.8e-37 128.5 1.7 3e-37 127.8 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RIO1 PF01163.22 OAG19087.1 - 5.4e-68 228.3 1.5 1.2e-67 227.2 1.5 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAG19087.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_10 PF13460.6 OAG19088.1 - 1.4e-05 25.0 0.0 4.9e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG19088.1 - 0.0055 16.2 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG19088.1 - 0.014 14.4 0.0 0.035 13.1 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family LCCL PF03815.19 OAG19088.1 - 0.23 11.6 0.1 0.48 10.6 0.1 1.5 1 0 0 1 1 1 0 LCCL domain YvrJ PF12841.7 OAG19089.1 - 0.22 11.1 0.4 0.94 9.1 0.0 2.2 3 0 0 3 3 3 0 YvrJ protein family DUF5446 PF17522.2 OAG19089.1 - 0.22 11.7 2.0 0.67 10.2 0.5 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5446) YEATS PF03366.16 OAG19090.1 - 3.9e-27 94.0 0.1 7.7e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 YEATS family Ribosomal_L29 PF00831.23 OAG19090.1 - 0.11 12.5 2.9 0.15 12.1 2.0 1.7 1 1 0 1 1 1 0 Ribosomal L29 protein ATP_bind_1 PF03029.17 OAG19091.1 - 4.6e-79 265.6 0.1 7.2e-79 265.0 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAG19091.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 OAG19091.1 - 0.00049 20.1 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG19091.1 - 0.0021 18.6 0.0 0.0083 16.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG19091.1 - 0.0035 17.6 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG19091.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAG19091.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 OAG19091.1 - 0.012 15.6 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 OAG19091.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG19091.1 - 0.016 15.6 0.0 0.066 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 OAG19091.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 OAG19091.1 - 0.022 15.3 0.0 0.073 13.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 OAG19091.1 - 0.027 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG19091.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 OAG19091.1 - 0.033 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OAG19091.1 - 0.04 12.9 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 OAG19091.1 - 0.041 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OAG19091.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG19091.1 - 0.059 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OAG19091.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 OAG19091.1 - 0.079 12.5 0.0 9.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF463 PF04317.12 OAG19091.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 T2SSE PF00437.20 OAG19091.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 OAG19091.1 - 0.11 12.0 0.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 OAG19091.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 OAG19091.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 OAG19091.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase MMR_HSR1 PF01926.23 OAG19091.1 - 0.17 12.0 0.0 0.7 10.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 OAG19091.1 - 0.17 12.2 0.0 0.8 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain S-AdoMet_synt_C PF02773.16 OAG19092.1 - 1.4e-66 222.7 0.4 1e-65 219.9 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAG19092.1 - 2e-46 157.1 0.0 3.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAG19092.1 - 2.1e-40 137.4 0.4 5.7e-40 136.0 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Titin_Z PF09042.11 OAG19093.1 - 0.11 12.5 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Titin Z Vps62 PF06101.11 OAG19094.1 - 3.1e-10 39.0 0.6 4.6e-10 38.4 0.6 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 TFIIIC_sub6 PF10419.9 OAG19095.1 - 9.8e-21 73.4 0.0 1.6e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain LHH PF14411.6 OAG19096.1 - 0.14 12.3 1.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Acetyltransf_3 PF13302.7 OAG19097.1 - 5.7e-28 98.3 0.0 7.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rft-1 PF04506.13 OAG19098.1 - 7.3e-150 500.1 10.8 1e-149 499.6 10.8 1.1 1 0 0 1 1 1 1 Rft protein Ppx-GppA PF02541.16 OAG19098.1 - 1.6e-41 142.6 0.0 3.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Polysacc_synt_3 PF13440.6 OAG19098.1 - 0.00012 21.4 11.9 0.034 13.4 8.9 4.1 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein GDA1_CD39 PF01150.17 OAG19098.1 - 0.23 10.1 0.0 0.4 9.3 0.0 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family ELFV_dehydrog PF00208.21 OAG19099.1 - 4.3e-67 226.4 0.0 8.3e-67 225.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAG19099.1 - 1.1e-18 66.3 0.1 3.4e-13 48.1 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OAG19099.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain p450 PF00067.22 OAG19101.1 - 4.3e-61 207.1 0.0 6.7e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aida_N PF08910.10 OAG19101.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Aida N-terminus Glyco_hydro_20 PF00728.22 OAG19102.1 - 1.6e-89 300.8 0.7 2e-89 300.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG19102.1 - 5.9e-27 95.0 0.1 1.4e-26 93.8 0.1 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG19102.1 - 0.00023 21.9 0.1 0.00083 20.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DNA_primase_S PF01896.19 OAG19103.1 - 1.8e-63 213.8 0.0 2.5e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF1917 PF08939.10 OAG19104.1 - 3.3e-80 269.8 0.0 4.5e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Amidohydro_1 PF01979.20 OAG19105.1 - 9.5e-28 97.5 0.0 3.7e-27 95.5 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG19105.1 - 1.2e-16 61.3 0.0 3.6e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family 5-nucleotidase PF06189.12 OAG19105.1 - 0.081 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase Lectin_leg-like PF03388.13 OAG19106.1 - 2.5e-30 105.5 0.0 4.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF812 PF05667.11 OAG19106.1 - 0.1 11.4 11.7 0.14 11.0 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF87 PF01935.17 OAG19106.1 - 0.18 11.9 4.8 0.26 11.3 4.8 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain FAM76 PF16046.5 OAG19106.1 - 7.4 5.8 9.3 10 5.4 9.3 1.1 1 0 0 1 1 1 0 FAM76 protein Band_7 PF01145.25 OAG19107.1 - 2e-21 76.8 5.3 4.3e-21 75.7 5.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 OAG19108.1 - 1.1e-08 34.7 0.0 3.2e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OAG19108.1 - 7.7e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG19108.1 - 0.28 11.1 2.7 0.4 10.6 0.7 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family CD99L2 PF12301.8 OAG19108.1 - 3.4 7.9 8.6 0.22 11.8 3.0 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 zf-C2H2 PF00096.26 OAG19109.1 - 1.1e-10 41.3 15.0 1.4e-05 25.2 4.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG19109.1 - 1.2e-07 31.8 7.8 0.0016 18.8 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG19109.1 - 2.7e-06 27.7 12.4 0.021 15.6 3.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG19109.1 - 0.0012 18.6 5.4 0.11 12.3 2.1 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OAG19109.1 - 4.6 7.3 10.7 4.9 7.3 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger ubiquitin PF00240.23 OAG19110.1 - 4.7e-34 116.0 0.6 8e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAG19110.1 - 4.2e-27 94.0 2.3 4.2e-27 94.0 2.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAG19110.1 - 2.6e-16 59.2 0.7 5e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG19110.1 - 3e-05 24.4 0.5 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG19110.1 - 0.0015 18.6 0.6 0.0035 17.4 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG19110.1 - 0.0053 17.1 1.1 0.0083 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG19110.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAG19110.1 - 0.012 16.1 0.8 0.018 15.6 0.8 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAG19110.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 OAG19110.1 - 0.029 14.6 0.3 0.049 13.9 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RecA_dep_nuc PF16786.5 OAG19112.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease SGL PF08450.12 OAG19113.1 - 2.6e-23 82.9 0.5 4.9e-23 82.0 0.5 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG19113.1 - 2.8e-05 24.2 0.1 0.00022 21.4 0.0 2.4 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.16 OAG19113.1 - 4.9e-05 23.4 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.21 OAG19113.1 - 0.012 15.6 0.9 2.4 8.4 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Pkinase PF00069.25 OAG19114.1 - 7.9e-41 140.2 0.0 1.3e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19114.1 - 1.1e-23 83.8 0.0 4.3e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase tRNA-synt_2 PF00152.20 OAG19115.1 - 3.9e-81 272.5 0.8 5.3e-81 272.1 0.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG19115.1 - 2e-06 27.7 0.1 5.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG19115.1 - 6.9e-06 25.7 0.1 0.01 15.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF1100 PF06500.11 OAG19116.1 - 2.1e-11 43.3 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 OAG19116.1 - 2.1e-06 27.6 0.1 0.00096 18.9 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 OAG19116.1 - 5.6e-05 22.9 0.0 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 OAG19116.1 - 0.00016 22.4 0.1 0.00025 21.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG19116.1 - 0.00017 21.0 0.0 0.00038 19.8 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OAG19116.1 - 0.0031 17.0 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OAG19116.1 - 0.0041 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG19116.1 - 0.02 14.3 0.2 0.052 13.0 0.2 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family USP8_dimer PF08969.11 OAG19116.1 - 0.029 14.6 0.8 0.063 13.5 0.8 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain BAAT_C PF08840.11 OAG19116.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 OAG19116.1 - 0.065 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAG19117.1 - 5e-23 82.1 0.5 6.6e-19 68.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG19117.1 - 1.5e-16 61.7 2.6 2e-15 58.0 2.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG19117.1 - 2e-10 40.3 0.0 4.4e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG19117.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAG19117.1 - 0.00085 18.9 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Antimicrobial14 PF08109.11 OAG19117.1 - 0.1 12.6 0.5 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Lactocin 705 family Arabinose_Iso_C PF11762.8 OAG19117.1 - 0.19 11.6 0.2 2 8.3 0.1 2.2 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain Ferritin_2 PF13668.6 OAG19120.1 - 3.6e-45 153.5 3.5 5.3e-45 153.0 3.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain DSBA PF01323.20 OAG19120.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glyco_hydro_17 PF00332.18 OAG19122.1 - 3.1e-09 36.9 1.6 6.9e-06 25.9 0.8 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Rhabdo_glycop PF00974.18 OAG19122.1 - 0.029 12.8 0.6 0.043 12.3 0.6 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein adh_short PF00106.25 OAG19124.1 - 0.00017 21.1 0.0 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG19124.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.18 OAG19125.1 - 2.1e-12 46.6 0.4 2.1e-12 46.6 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SNase PF00565.17 OAG19126.1 - 1.9e-69 230.9 1.1 1.1e-25 90.1 0.1 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAG19126.1 - 1.2e-26 93.1 0.0 3.2e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Tudor domain HeLo PF14479.6 OAG19127.1 - 1.1e-09 38.4 0.0 0.00062 19.7 0.0 2.7 2 0 0 2 2 2 2 Prion-inhibition and propagation Pkinase PF00069.25 OAG19127.1 - 0.0099 15.3 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19127.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG19127.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPX2_importin PF12214.8 OAG19127.1 - 0.14 12.3 2.6 0.36 11.0 2.6 1.6 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein Glyco_transf_34 PF05637.12 OAG19128.1 - 9.4e-11 41.9 0.4 3.2e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DCP1 PF06058.13 OAG19132.1 - 0.21 11.5 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family SOG2 PF10428.9 OAG19133.1 - 3.9 6.6 13.0 4 6.5 13.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DAO PF01266.24 OAG19134.1 - 1.1e-47 163.4 0.5 1.2e-47 163.2 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG19134.1 - 3.2e-05 23.3 0.1 9.4e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG19134.1 - 8.4e-05 21.9 0.4 0.0037 16.6 0.5 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG19134.1 - 0.00019 21.6 0.1 0.0005 20.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG19134.1 - 0.00037 19.8 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 OAG19134.1 - 0.0054 15.6 0.1 0.01 14.6 0.0 1.5 2 0 0 2 2 2 1 MCRA family SelB-wing_2 PF09106.11 OAG19134.1 - 0.079 13.2 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Amino_oxidase PF01593.24 OAG19134.1 - 0.11 11.8 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG19134.1 - 0.11 13.1 0.6 2.2 8.9 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3530 PF12048.8 OAG19134.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DJ-1_PfpI PF01965.24 OAG19135.1 - 6.1e-18 65.2 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HigB_toxin PF09907.9 OAG19135.1 - 0.076 13.2 0.1 0.63 10.3 0.2 2.2 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system RTA1 PF04479.13 OAG19136.1 - 7.3e-68 228.3 3.6 1.2e-67 227.6 3.6 1.3 1 0 0 1 1 1 1 RTA1 like protein TMEM223 PF14640.6 OAG19136.1 - 0.21 11.8 1.1 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 223 HemY_N PF07219.13 OAG19136.1 - 2.3 8.5 7.8 7.6 6.8 0.0 3.1 2 1 1 3 3 3 0 HemY protein N-terminus DHHC PF01529.20 OAG19136.1 - 6.6 6.8 6.5 48 4.0 0.3 3.1 3 1 0 3 3 3 0 DHHC palmitoyltransferase Haspin_kinase PF12330.8 OAG19137.1 - 4.8e-35 121.2 0.0 2.3e-26 92.6 0.0 3.1 2 1 0 2 2 2 2 Haspin like kinase domain Reductase_C PF14759.6 OAG19137.1 - 0.026 15.1 0.0 0.17 12.5 0.0 2.4 3 0 0 3 3 3 0 Reductase C-terminal Response_reg PF00072.24 OAG19138.1 - 3e-20 72.4 0.0 3.9e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Pkinase PF00069.25 OAG19139.1 - 3.5e-67 226.5 0.0 4.4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19139.1 - 3.5e-34 118.3 0.0 4.7e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG19139.1 - 9.9e-05 21.4 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG19139.1 - 0.0011 18.9 0.0 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG19139.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-PolyVal PF18762.1 OAG19139.1 - 0.034 14.1 0.1 7.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Seadorna_VP7 PF07387.11 OAG19139.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 OAG19139.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ATP-synt_C PF00137.21 OAG19140.1 - 7.7e-32 109.4 36.9 3.5e-20 72.1 14.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 OAG19141.1 - 2.3e-80 270.1 0.0 3.4e-79 266.3 0.0 2.1 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 OAG19141.1 - 1.5e-48 164.3 0.0 1.5e-48 164.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 OAG19141.1 - 4e-39 134.7 0.3 7.7e-39 133.8 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAG19141.1 - 3.1e-14 52.8 0.0 7.4e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 OAG19141.1 - 0.086 13.4 0.1 0.81 10.2 0.0 2.7 2 1 1 3 3 3 0 PH domain Tnp_P_element_C PF12596.8 OAG19141.1 - 0.19 12.3 0.7 26 5.4 0.4 2.7 2 0 0 2 2 2 0 87kDa Transposase EthD PF07110.11 OAG19142.1 - 6.1e-06 27.3 0.1 0.042 15.0 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 OAG19142.1 - 0.0043 17.5 0.0 2.2 8.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Ins_P5_2-kin PF06090.12 OAG19143.1 - 1.5e-53 182.3 0.0 2e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF952 PF06108.12 OAG19144.1 - 3.9e-22 78.1 0.0 5.2e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) WD40 PF00400.32 OAG19145.1 - 4.3e-42 141.3 17.3 1e-06 29.4 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 OAG19145.1 - 5.9e-12 45.3 0.1 1.2e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG19145.1 - 2.7e-10 39.9 0.7 2e-09 37.1 0.1 2.3 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 OAG19145.1 - 2e-09 37.6 0.1 0.098 13.0 0.0 5.8 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG19145.1 - 1.3e-06 27.4 4.3 0.17 10.5 0.2 4.5 3 1 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG19145.1 - 6.7e-05 22.4 0.2 0.00027 20.4 0.2 1.8 2 0 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 OAG19145.1 - 0.00012 22.1 0.0 1.5 8.9 0.0 4.2 4 1 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 OAG19145.1 - 0.002 18.0 0.1 0.0074 16.2 0.0 2.0 2 0 0 2 2 2 1 F-box NAR2 PF16974.5 OAG19145.1 - 0.54 9.6 3.6 3.1 7.2 3.2 2.2 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory PALB2_WD40 PF16756.5 OAG19145.1 - 0.95 8.3 7.7 22 3.8 0.1 4.0 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain APG17 PF04108.12 OAG19146.1 - 7.8e-113 377.6 0.8 9.2e-113 377.3 0.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Bacillus_HBL PF05791.11 OAG19146.1 - 0.0027 17.6 0.0 0.089 12.6 0.0 3.0 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 OAG19146.1 - 0.0034 17.4 5.3 1.5 8.8 0.0 3.5 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 OAG19146.1 - 0.034 14.8 4.2 8.6 7.1 0.1 3.5 3 0 0 3 3 3 0 Initiation control protein YabA TMPIT PF07851.13 OAG19146.1 - 0.17 11.1 2.0 2.3 7.4 0.0 2.7 3 0 0 3 3 3 0 TMPIT-like protein Rab5-bind PF09311.11 OAG19146.1 - 0.25 10.7 10.3 0.24 10.8 4.5 3.2 3 1 0 3 3 3 0 Rabaptin-like protein CREPT PF16566.5 OAG19146.1 - 0.43 10.8 6.7 13 5.9 0.1 3.9 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour EzrA PF06160.12 OAG19146.1 - 0.55 8.3 8.7 0.11 10.6 0.7 2.9 3 1 0 3 3 3 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 OAG19146.1 - 1.3 9.4 8.5 1.8 8.9 0.2 3.7 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIP1_clath_bdg PF16515.5 OAG19146.1 - 1.7 9.3 14.4 21 5.8 0.7 3.8 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.12 OAG19146.1 - 2.1 8.4 10.1 4.9 7.2 0.7 3.0 3 0 0 3 3 3 0 Laminin Domain II MCPsignal PF00015.21 OAG19146.1 - 2.4 7.9 9.6 0.12 12.2 0.5 3.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.12 OAG19146.1 - 2.6 8.1 12.5 0.18 11.9 0.6 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 OAG19146.1 - 4.7 7.5 6.3 16 5.9 0.3 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OAG19146.1 - 6.8 7.2 10.9 4.9 7.7 3.0 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Methyltransf_23 PF13489.6 OAG19147.1 - 6e-25 88.0 0.0 9.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG19147.1 - 3.2e-11 43.8 0.0 9.1e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG19147.1 - 2.3e-09 37.8 0.0 4.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG19147.1 - 2.6e-07 30.5 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG19147.1 - 1.7e-06 28.6 0.0 7.7e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG19147.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 OAG19147.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 OAG19147.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAG19147.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 OAG19147.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG19147.1 - 0.064 12.6 0.0 1.2 8.4 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 OAG19147.1 - 0.18 11.5 0.0 0.52 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) p450 PF00067.22 OAG19148.1 - 2.8e-54 184.6 0.0 3.7e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG19149.1 - 4.7e-24 85.2 0.0 6.5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19149.1 - 9.7e-20 70.8 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG19149.1 - 0.0014 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain EMC1_C PF07774.13 OAG19150.1 - 3.8e-74 249.0 0.0 6.3e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAG19150.1 - 8.4e-35 120.5 6.5 2.4e-32 112.4 2.3 3.1 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 OAG19150.1 - 5.6e-07 29.2 1.9 0.053 13.5 0.0 5.4 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 OAG19150.1 - 0.14 12.7 1.0 7.8 7.1 0.0 4.4 4 1 1 5 5 5 0 PQQ-like domain Ras PF00071.22 OAG19152.1 - 2.3e-48 163.8 0.0 3.3e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Grg1 PF11034.8 OAG19152.1 - 5.6e-26 90.6 8.7 8.5e-26 90.0 8.7 1.3 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Roc PF08477.13 OAG19152.1 - 4.1e-15 56.1 0.0 6.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG19152.1 - 2.1e-06 27.3 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAG19152.1 - 0.0018 18.2 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAG19152.1 - 0.0021 17.6 0.0 0.037 13.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG19152.1 - 0.0041 17.2 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4491 PF14898.6 OAG19152.1 - 0.0082 16.6 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4491) AAA_22 PF13401.6 OAG19152.1 - 0.033 14.5 0.1 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain MARVEL PF01284.23 OAG19153.1 - 1e-06 28.8 9.0 1.7e-06 28.1 9.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain OST3_OST6 PF04756.13 OAG19153.1 - 0.36 10.1 2.3 1.7 8.0 0.3 2.1 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF4079 PF13301.6 OAG19153.1 - 1.2 9.3 5.9 3.2 7.9 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2207 PF09972.9 OAG19153.1 - 9.3 4.9 6.6 17 4.0 6.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GST_C PF00043.25 OAG19154.1 - 2.6e-17 62.8 0.2 2.3e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG19154.1 - 2.7e-11 43.5 0.0 6.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG19154.1 - 9.4e-09 35.2 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG19154.1 - 8.1e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG19154.1 - 2.1e-07 31.2 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG19154.1 - 6.6e-06 26.3 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAG19154.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cation_efflux PF01545.21 OAG19155.1 - 4e-45 154.0 9.8 4e-45 154.0 9.8 2.4 3 0 0 3 3 3 1 Cation efflux family CDC45 PF02724.14 OAG19155.1 - 5.2 5.2 6.0 8 4.6 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_trans_1_4 PF13692.6 OAG19156.1 - 4.7e-06 27.1 0.0 2.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG19156.1 - 7.4e-06 26.1 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAG19156.1 - 3e-05 23.6 0.0 0.00033 20.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 TrkH PF02386.16 OAG19158.1 - 1.2e-78 264.8 11.6 1.4e-78 264.6 1.4 2.1 2 0 0 2 2 2 2 Cation transport protein DUF5472 PF17566.2 OAG19158.1 - 0.15 12.0 1.2 0.39 10.7 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Asp_protease_2 PF13650.6 OAG19159.1 - 6.2e-14 52.4 0.0 1e-05 26.1 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG19159.1 - 1.6e-12 47.8 0.0 3.8e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 OAG19159.1 - 0.00044 20.0 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Type_III_YscG PF09477.10 OAG19159.1 - 0.085 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) HTH_Tnp_Tc5 PF03221.16 OAG19160.1 - 8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG19160.1 - 0.0046 16.7 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_6 PF01418.17 OAG19160.1 - 0.0084 16.1 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family ANTH PF07651.16 OAG19160.1 - 0.052 12.5 0.2 0.069 12.1 0.2 1.2 1 0 0 1 1 1 0 ANTH domain XPG_N PF00752.17 OAG19160.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.7 1 1 0 1 1 1 0 XPG N-terminal domain DUF3384 PF11864.8 OAG19161.1 - 7.9e-127 424.1 1.1 1.7e-126 422.9 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OAG19161.1 - 1.8e-50 171.1 0.0 2.9e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAG19161.1 - 3.4e-37 128.4 8.8 1.3e-34 119.9 0.7 3.5 4 0 0 4 4 4 3 Tuberin BCDHK_Adom3 PF10436.9 OAG19162.1 - 2e-45 154.6 0.1 2.9e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG19162.1 - 5.1e-10 39.8 0.4 2.8e-07 31.0 0.4 3.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 OAG19163.1 - 0.00016 22.3 0.1 0.00019 22.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 OAG19164.1 - 1.8e-96 323.0 0.1 1.8e-96 323.0 0.1 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG19164.1 - 5.1e-28 97.0 0.0 1.6e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OAG19164.1 - 8.9e-06 25.4 0.0 0.0021 17.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAG19164.1 - 0.00012 22.3 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG19164.1 - 0.00044 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG19164.1 - 0.00072 19.6 0.0 0.0027 17.7 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG19164.1 - 0.00079 19.6 1.2 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG19164.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAG19164.1 - 0.0026 18.3 0.1 0.008 16.7 0.1 1.8 1 0 0 1 1 1 1 ABC transporter W2 PF02020.18 OAG19164.1 - 0.0049 17.0 0.1 0.016 15.3 0.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NB-ARC PF00931.22 OAG19164.1 - 0.0062 15.8 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 OAG19164.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 OAG19164.1 - 0.02 15.2 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAG19164.1 - 0.022 14.6 1.0 0.17 11.8 0.1 2.6 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 OAG19164.1 - 0.028 14.0 0.2 0.057 13.0 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OAG19164.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG19164.1 - 0.037 14.4 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAG19164.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 OAG19164.1 - 0.054 14.0 0.2 0.054 14.0 0.2 3.5 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 OAG19164.1 - 0.059 13.3 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 OAG19164.1 - 0.064 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 OAG19164.1 - 0.081 12.9 0.1 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OAG19164.1 - 0.091 12.5 0.1 0.79 9.5 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OAG19164.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 OAG19164.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase AAA_14 PF13173.6 OAG19164.1 - 0.14 12.2 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 OAG19164.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OAG19164.1 - 0.19 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Wzy_C_2 PF11846.8 OAG19164.1 - 0.24 11.3 0.2 0.44 10.5 0.2 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ATPase_2 PF01637.18 OAG19164.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea PGAP1 PF07819.13 OAG19165.1 - 9.4e-93 310.2 0.0 1.4e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG19165.1 - 2.6e-06 28.2 0.9 2.6e-06 28.2 0.9 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG19165.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OAG19165.1 - 0.0039 16.7 0.2 0.0073 15.8 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAG19165.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG19165.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 OAG19165.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 OAG19165.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 OAG19165.1 - 0.17 11.6 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Zn_clus PF00172.18 OAG19168.1 - 2.1e-07 30.9 12.4 3.9e-07 30.1 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rsa3 PF14615.6 OAG19168.1 - 0.12 11.9 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Ribosome-assembly protein 3 TPK_catalytic PF04263.16 OAG19169.1 - 1.2e-33 115.7 0.0 1.6e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAG19169.1 - 2.2e-18 65.7 0.0 3.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SKN1 PF03935.15 OAG19170.1 - 7.8e-211 700.8 0.3 1e-210 700.4 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) His_Phos_2 PF00328.22 OAG19171.1 - 2.2e-24 86.5 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MIF4G PF02854.19 OAG19172.1 - 4.9e-58 196.3 0.1 1.3e-29 103.4 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OAG19172.1 - 1.9e-38 132.3 5.7 1.9e-38 132.3 5.7 3.1 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Chitin_synth_2 PF03142.15 OAG19173.1 - 7.2e-24 84.3 1.1 7.2e-24 84.3 1.1 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG19173.1 - 8.2e-16 58.5 1.9 8.2e-16 58.5 1.9 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG19173.1 - 1.5e-11 44.6 0.0 3.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG19173.1 - 0.0032 17.3 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DAO PF01266.24 OAG19174.1 - 3.4e-61 207.8 0.1 4.4e-61 207.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG19174.1 - 2.9e-06 27.4 0.3 7.1e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG19174.1 - 0.00053 19.3 0.1 0.037 13.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG19174.1 - 0.001 18.2 0.5 0.0033 16.6 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG19174.1 - 0.0094 15.2 0.3 0.048 12.9 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG19174.1 - 0.023 13.7 0.1 0.37 9.8 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 OAG19174.1 - 0.031 14.6 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 OAG19174.1 - 0.043 13.1 0.3 0.12 11.6 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 OAG19174.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG19174.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NUDIX PF00293.28 OAG19175.1 - 9.8e-12 45.1 0.1 3.8e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF3305 PF11749.8 OAG19175.1 - 0.043 13.9 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) End3 PF12761.7 OAG19176.1 - 1.9e-71 240.4 0.1 2.5e-71 240.0 0.1 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 OAG19176.1 - 3.9e-49 164.9 0.0 1e-47 160.4 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OAG19176.1 - 5.3e-09 35.0 0.7 9.8e-08 31.0 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAG19176.1 - 8.8e-08 32.5 0.1 5.4e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OAG19176.1 - 4.3e-07 29.7 0.3 0.00025 20.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG19176.1 - 0.0001 22.0 1.5 0.00035 20.3 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OAG19176.1 - 0.0018 17.7 0.8 0.0042 16.5 0.1 2.1 2 0 0 2 2 2 1 EF hand Phage_GP20 PF06810.11 OAG19176.1 - 0.031 14.1 3.6 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 OAG19176.1 - 0.078 13.5 0.3 0.91 10.0 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 OAG19176.1 - 0.082 12.5 2.4 6.4 6.3 0.5 2.2 2 0 0 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 OAG19176.1 - 0.14 12.2 3.7 8.3 6.5 0.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GTP-bdg_M PF16360.5 OAG19176.1 - 0.33 11.6 4.8 0.18 12.4 1.5 2.1 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Med9 PF07544.13 OAG19176.1 - 0.43 10.7 4.8 0.53 10.4 0.0 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TSC22 PF01166.18 OAG19176.1 - 2 8.8 7.9 4.2 7.7 0.6 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Chitin_synth_2 PF03142.15 OAG19177.1 - 7.4e-232 770.6 0.1 1.2e-231 770.0 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 OAG19177.1 - 2.8e-14 52.7 0.7 9.4e-14 51.1 0.6 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAG19177.1 - 2.2e-13 50.6 2.1 2.2e-13 50.6 2.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG19177.1 - 1.6e-12 47.8 0.0 5.7e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 OAG19177.1 - 1.1e-10 41.4 0.1 8e-08 32.3 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 OAG19177.1 - 2.2e-06 26.2 0.0 4.9e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 OAG19177.1 - 0.00023 21.0 0.0 0.032 14.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG19177.1 - 0.00026 20.5 0.1 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 OAG19178.1 - 1.1e-240 799.8 0.5 1.4e-240 799.4 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAG19178.1 - 3.7e-80 270.0 0.0 3.6e-79 266.8 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 OAG19178.1 - 2.4e-19 69.3 0.4 7.7e-15 54.8 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 OAG19178.1 - 2.9e-16 59.1 0.5 7.7e-16 57.8 0.5 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAG19178.1 - 5.2e-12 46.1 4.8 5.2e-12 46.1 4.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG19178.1 - 2.4e-11 44.0 0.5 9.2e-10 38.8 0.2 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG19178.1 - 9.9e-05 22.2 0.0 0.09 12.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 OAG19178.1 - 0.083 13.2 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG19178.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OAG19178.1 - 0.17 12.4 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 OAG19179.1 - 6.6e-34 117.2 0.0 4.2e-33 114.5 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG19179.1 - 1.6e-17 63.5 0.1 4.7e-17 62.0 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAG19179.1 - 6.6e-11 42.5 0.1 6.6e-11 42.5 0.1 4.1 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OAG19179.1 - 4.1e-10 39.4 0.1 1.5e-09 37.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OAG19179.1 - 3.1e-07 30.5 0.2 9.9e-06 25.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OAG19179.1 - 0.0008 19.3 0.0 0.0008 19.3 0.0 2.5 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein Roc PF08477.13 OAG19179.1 - 0.0013 19.0 0.0 0.0039 17.4 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TrkA_C PF02080.21 OAG19179.1 - 0.072 12.9 0.6 6.2 6.7 0.1 3.2 3 0 0 3 3 3 0 TrkA-C domain MFS_1 PF07690.16 OAG19181.1 - 1.5e-36 126.1 42.7 1.5e-36 126.1 42.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG19181.1 - 2.2e-13 49.9 4.7 2.2e-13 49.9 4.7 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAG19181.1 - 0.0074 14.6 9.3 0.039 12.2 3.6 3.1 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Pex19 PF04614.12 OAG19182.1 - 0.0024 17.7 12.6 0.03 14.1 9.5 2.3 1 1 1 2 2 2 2 Pex19 protein family Cortex-I_coil PF09304.10 OAG19182.1 - 0.0046 17.2 6.4 0.077 13.2 0.4 3.0 2 1 1 3 3 3 1 Cortexillin I, coiled coil DUF3861 PF12977.7 OAG19182.1 - 0.013 15.6 5.3 6.3 7.0 0.0 4.0 1 1 4 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Dfp1_Him1_M PF08630.10 OAG19182.1 - 0.017 15.3 2.9 0.14 12.4 0.3 2.4 1 1 0 2 2 2 0 Dfp1/Him1, central region DUF4974 PF16344.5 OAG19182.1 - 0.023 14.7 0.0 8.3 6.5 0.0 3.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4974) PMI_typeI PF01238.21 OAG19182.1 - 0.042 13.0 0.9 0.078 12.2 0.6 1.6 1 1 1 2 2 2 0 Phosphomannose isomerase type I RuvB_N PF05496.12 OAG19182.1 - 0.052 13.3 3.5 2.7 7.7 0.1 3.3 3 1 1 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain FCD PF07729.12 OAG19182.1 - 0.066 13.6 25.4 9.9 6.6 2.1 4.9 1 1 4 5 5 5 0 FCD domain VWA_2 PF13519.6 OAG19182.1 - 0.14 12.8 2.6 5.3 7.7 0.0 2.9 1 1 2 3 3 3 0 von Willebrand factor type A domain Phage_T7_Capsid PF05396.11 OAG19182.1 - 0.52 10.7 14.3 5.5 7.4 0.2 3.6 1 1 2 3 3 3 0 Phage T7 capsid assembly protein ECH_2 PF16113.5 OAG19182.1 - 0.7 9.3 12.1 3.7 7.0 4.6 2.4 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase PPP4R2 PF09184.11 OAG19182.1 - 1.5 8.3 5.8 1.8 8.1 5.8 1.1 1 0 0 1 1 1 0 PPP4R2 TPR_16 PF13432.6 OAG19182.1 - 2.9 8.6 30.5 11 6.8 0.7 5.4 4 2 1 5 5 5 0 Tetratricopeptide repeat MHB PF16525.5 OAG19182.1 - 4.2 7.7 9.7 3 8.1 0.8 2.9 1 1 0 2 2 2 0 Haemophore, haem-binding ATP-synt_C PF00137.21 OAG19183.1 - 9.4e-13 48.3 9.9 9.4e-13 48.3 9.9 2.5 1 1 2 3 3 3 2 ATP synthase subunit C GATA PF00320.27 OAG19184.1 - 2e-14 52.9 2.7 3.4e-14 52.2 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Atg14 PF10186.9 OAG19184.1 - 0.0037 16.4 4.4 0.0064 15.6 4.4 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 OAG19184.1 - 0.0073 14.5 2.4 0.0095 14.2 2.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Nsp1_C PF05064.13 OAG19184.1 - 0.0084 15.9 2.5 0.013 15.3 2.5 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.12 OAG19184.1 - 0.026 14.6 6.3 0.048 13.7 6.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CASP_C PF08172.12 OAG19184.1 - 0.028 13.8 4.0 0.045 13.1 4.0 1.3 1 0 0 1 1 1 0 CASP C terminal Macoilin PF09726.9 OAG19184.1 - 0.048 12.2 4.6 0.064 11.8 4.6 1.1 1 0 0 1 1 1 0 Macoilin family TF_Zn_Ribbon PF08271.12 OAG19184.1 - 0.052 13.1 0.6 0.089 12.3 0.6 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3552 PF12072.8 OAG19184.1 - 0.13 11.7 8.8 0.17 11.3 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ArfGap PF01412.18 OAG19184.1 - 0.31 11.1 1.1 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Pox_A_type_inc PF04508.12 OAG19184.1 - 0.38 10.7 7.5 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat JIP_LZII PF16471.5 OAG19184.1 - 2.9 8.1 9.0 17 5.6 9.0 2.0 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 OAG19184.1 - 4.2 7.9 12.4 2.8 8.5 9.3 1.9 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 OAG19184.1 - 9.6 6.5 8.9 10 6.4 6.6 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SRP68 PF16969.5 OAG19185.1 - 5.8e-186 619.8 8.3 6.5e-186 619.6 8.3 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 GLTP PF08718.11 OAG19185.1 - 0.023 15.0 0.7 0.062 13.6 0.7 1.7 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) PPR_2 PF13041.6 OAG19186.1 - 1.3e-18 66.9 0.1 3.9e-05 23.8 0.0 7.3 7 1 1 8 8 8 4 PPR repeat family PPR PF01535.20 OAG19186.1 - 2e-11 43.3 6.0 0.15 12.4 0.1 8.8 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 OAG19186.1 - 5.4e-09 36.0 0.1 0.12 12.4 0.0 6.1 5 2 2 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OAG19186.1 - 3.1e-07 30.0 0.2 0.0038 16.6 0.1 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 OAG19186.1 - 0.0013 17.7 0.0 0.51 9.1 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S27 PPR_1 PF12854.7 OAG19186.1 - 0.0051 16.5 0.7 13 5.5 0.1 4.6 4 0 0 4 4 4 1 PPR repeat BTAD PF03704.17 OAG19186.1 - 0.04 14.4 6.1 0.58 10.6 0.0 4.2 5 1 0 5 5 5 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 OAG19186.1 - 0.11 13.4 7.9 74 4.6 0.0 7.4 8 1 1 9 9 9 0 Tetratricopeptide repeat MMS1_N PF10433.9 OAG19187.1 - 1.4e-51 175.6 0.0 2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 OAG19188.1 - 2.6e-26 92.6 0.0 3.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prefoldin_2 PF01920.20 OAG19188.1 - 0.095 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit GILT PF03227.16 OAG19189.1 - 9.6 6.5 27.2 0.5 10.7 0.6 4.5 4 0 0 4 4 4 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Internalin_N PF12354.8 OAG19191.1 - 1.2 9.3 7.0 8.9 6.5 0.5 2.8 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal zf-C2H2 PF00096.26 OAG19192.1 - 4e-10 39.6 5.4 7.7e-06 26.1 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG19192.1 - 9.8e-05 22.9 2.7 0.007 17.1 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAG19192.1 - 0.0075 16.4 1.1 1.7 8.7 0.0 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 OAG19192.1 - 0.12 12.8 0.4 0.12 12.8 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ferric_reduct PF01794.19 OAG19193.1 - 2.2e-21 76.3 5.4 2.2e-21 76.3 5.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG19193.1 - 6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG19193.1 - 4.6e-11 43.1 0.0 6.9e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OAG19193.1 - 0.00066 20.3 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Sdh_cyt PF01127.22 OAG19193.1 - 0.0043 17.1 2.0 0.013 15.6 2.0 1.8 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit p450 PF00067.22 OAG19195.1 - 7.4e-50 170.0 0.0 9.2e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 OAG19196.1 - 3.9e-18 66.4 0.0 5.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG19196.1 - 0.0051 17.3 0.1 0.0094 16.4 0.1 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Glyco_hydro_31 PF01055.26 OAG19197.1 - 2.2e-105 353.4 3.3 2.7e-105 353.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG19197.1 - 4.8e-13 49.2 0.1 1.6e-12 47.6 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Melibiase PF02065.18 OAG19197.1 - 0.062 12.2 0.4 0.1 11.6 0.4 1.3 1 0 0 1 1 1 0 Melibiase Sugar_tr PF00083.24 OAG19198.1 - 1.2e-96 324.4 27.9 1.4e-96 324.2 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19198.1 - 1.4e-29 103.2 30.3 2e-29 102.6 30.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG19198.1 - 3.1e-07 29.2 1.7 7.6e-07 27.9 1.7 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0060 PF02694.15 OAG19198.1 - 0.011 15.9 2.2 0.27 11.5 0.1 3.2 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2530 PF10745.9 OAG19198.1 - 2.9 8.2 9.4 0.25 11.6 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) AAA PF00004.29 OAG19199.1 - 3.8e-11 43.6 0.0 8.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG19199.1 - 2.3e-06 27.6 0.2 4.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 OAG19199.1 - 1.7e-05 25.1 0.0 6.1e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG19199.1 - 2.3e-05 24.4 0.1 5.2e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG19199.1 - 4.1e-05 23.4 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG19199.1 - 0.00073 20.0 0.0 0.0048 17.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG19199.1 - 0.0053 16.9 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAG19199.1 - 0.0097 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 OAG19199.1 - 0.011 15.6 0.2 0.033 14.1 0.2 1.9 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 OAG19199.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG19199.1 - 0.035 14.0 0.6 16 5.3 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OAG19199.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 OAG19199.1 - 0.13 12.6 0.0 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG19199.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAG19199.1 - 0.22 12.1 2.6 0.29 11.7 0.1 2.6 4 0 0 4 4 3 0 AAA domain RPN2_C PF18004.1 OAG19199.1 - 0.73 9.7 8.2 2.7 7.9 8.2 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_11 PF13086.6 OAG19199.1 - 7.2 6.3 10.0 3 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain adh_short PF00106.25 OAG19201.1 - 1.8e-27 96.1 0.2 1e-25 90.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19201.1 - 1.2e-21 77.3 0.1 2.4e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19201.1 - 1.9e-09 37.7 0.1 2.9e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2431 PF10354.9 OAG19201.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) THF_DHG_CYH_C PF02882.19 OAG19201.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG19201.1 - 0.029 13.8 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SMRP1 PF15181.6 OAG19205.1 - 0.0039 16.8 0.5 0.0044 16.7 0.5 1.1 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 DTHCT PF08070.11 OAG19206.1 - 9.7 7.0 20.2 0.066 13.9 8.4 3.2 2 1 1 3 3 3 0 DTHCT (NUC029) region DUF3644 PF12358.8 OAG19207.1 - 0.094 13.2 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Peptidase_M14 PF00246.24 OAG19208.1 - 6.2e-74 249.4 0.1 9.9e-74 248.7 0.1 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Methyltransf_11 PF08241.12 OAG19211.1 - 1.4e-10 41.7 0.0 2.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG19211.1 - 1.8e-09 38.2 0.0 3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG19211.1 - 4.5e-06 26.6 0.3 2.2e-05 24.4 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG19211.1 - 1.6e-05 25.6 0.4 2.8e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG19211.1 - 9.1e-05 22.3 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CPBP PF02517.16 OAG19212.1 - 5.3e-16 58.8 8.4 5.3e-16 58.8 8.4 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Abhydrolase_9_N PF15420.6 OAG19212.1 - 0.045 13.7 1.2 0.13 12.2 0.8 1.9 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus eIF-6 PF01912.18 OAG19214.1 - 2.1e-80 268.8 1.6 2.9e-80 268.3 1.6 1.2 1 0 0 1 1 1 1 eIF-6 family Es2 PF09751.9 OAG19215.1 - 1.5e-119 400.6 5.0 1.8e-119 400.3 5.0 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 Sds3 PF08598.11 OAG19216.1 - 9e-06 25.8 3.4 9e-06 25.8 3.4 2.8 3 0 0 3 3 3 1 Sds3-like XPC-binding PF09280.11 OAG19218.1 - 2.8e-24 84.6 14.9 5.3e-24 83.7 14.9 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 OAG19218.1 - 2.1e-21 75.4 7.0 7e-13 48.2 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OAG19218.1 - 1.2e-20 73.0 0.1 1.8e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG19218.1 - 2.8e-05 23.9 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAG19218.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 OAG19218.1 - 0.016 15.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Clathrin_H_link PF13838.6 OAG19218.1 - 0.029 14.3 0.2 0.17 11.8 0.2 2.4 1 0 0 1 1 1 0 Clathrin-H-link MCM_N PF14551.6 OAG19218.1 - 0.075 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Kri1_C PF12936.7 OAG19219.1 - 9.1e-30 102.7 0.8 9.1e-30 102.7 0.8 4.1 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 OAG19219.1 - 6.5e-27 94.1 14.9 6.5e-27 94.1 14.9 5.6 4 2 2 6 6 6 1 KRI1-like family VASt PF16016.5 OAG19220.1 - 7.2e-28 97.9 0.0 1.9e-27 96.6 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 OAG19220.1 - 4e-16 59.5 0.0 7.8e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAG19220.1 - 6.6e-10 39.4 0.2 2.9e-09 37.4 0.1 2.2 2 0 0 2 2 2 1 PH domain BAR PF03114.18 OAG19220.1 - 0.00023 20.9 0.3 0.00063 19.5 0.3 1.7 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 OAG19220.1 - 0.007 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF2353 PF09789.9 OAG19220.1 - 0.086 12.2 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3084 PF11283.8 OAG19220.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) Nitr_red_assoc PF09655.10 OAG19220.1 - 0.13 12.9 0.4 6.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PH_13 PF16652.5 OAG19220.1 - 0.53 10.1 2.3 0.52 10.1 0.0 2.1 3 0 0 3 3 3 0 Pleckstrin homology domain ubiquitin PF00240.23 OAG19221.1 - 1e-17 63.6 0.0 2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG19221.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG19221.1 - 0.17 12.5 0.0 0.42 11.2 0.0 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_S14 PF00253.21 OAG19222.1 - 1e-11 44.4 0.2 1.2e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e WW PF00397.26 OAG19225.1 - 3.3e-10 39.9 7.8 7.6e-10 38.7 7.8 1.7 1 0 0 1 1 1 1 WW domain DAO PF01266.24 OAG19226.1 - 5.4e-66 223.6 0.4 6.2e-66 223.4 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG19226.1 - 1.8e-05 24.1 0.0 0.062 12.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG19226.1 - 3.5e-05 24.0 0.1 7.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG19226.1 - 5.3e-05 22.3 0.2 0.011 14.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG19226.1 - 0.001 19.1 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG19226.1 - 0.0027 16.8 0.1 0.96 8.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 OAG19226.1 - 0.0056 15.8 0.4 0.031 13.3 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAG19226.1 - 0.028 13.6 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAG19226.1 - 0.03 14.9 0.3 0.38 11.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAG19226.1 - 0.04 12.5 0.0 5.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Sacchrp_dh_NADP PF03435.18 OAG19226.1 - 0.054 13.7 0.2 0.22 11.8 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 OAG19226.1 - 0.093 12.8 0.1 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MCRA PF06100.11 OAG19226.1 - 0.16 10.7 0.5 0.46 9.2 0.2 1.7 2 0 0 2 2 2 0 MCRA family RHD3 PF05879.12 OAG19227.1 - 0 1046.2 0.0 0 1045.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OAG19227.1 - 5.1e-08 32.5 0.1 8.6e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OAG19227.1 - 1.3e-05 25.3 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAG19227.1 - 0.00021 21.3 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OAG19227.1 - 0.035 13.4 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 OAG19227.1 - 0.035 14.3 0.7 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain HIG_1_N PF04588.13 OAG19229.1 - 6.4e-06 26.3 0.2 6.4e-06 26.3 0.2 2.1 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Zip PF02535.22 OAG19229.1 - 2.6 7.2 3.8 7 5.8 4.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter PUF PF00806.19 OAG19230.1 - 3.4e-34 114.6 2.9 8.8e-05 22.0 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 OAG19230.1 - 0.053 14.3 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Peptidase_S9 PF00326.21 OAG19231.1 - 4.7e-07 29.5 0.3 9.2e-07 28.5 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPT PF03151.16 OAG19232.1 - 6.5e-58 196.4 11.1 7.9e-58 196.1 11.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG19232.1 - 2.2e-10 40.2 13.3 4.5e-10 39.2 13.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG19232.1 - 1e-08 35.4 28.7 8.2e-06 26.0 10.8 2.9 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG19232.1 - 0.012 14.8 2.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter Wzy_C PF04932.15 OAG19232.1 - 0.038 13.6 0.4 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 O-Antigen ligase Phage_holin_5_2 PF16079.5 OAG19232.1 - 1.1 9.7 5.7 1.3 9.4 1.0 3.0 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Ras PF00071.22 OAG19234.1 - 1.8e-63 213.0 0.2 2.1e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG19234.1 - 2.1e-35 121.5 0.2 2.9e-35 121.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG19234.1 - 3e-13 49.6 0.1 3.9e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG19234.1 - 8.1e-08 32.3 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG19234.1 - 9.1e-05 22.4 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG19234.1 - 0.00025 20.7 0.1 0.001 18.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG19234.1 - 0.00039 19.8 0.1 0.00062 19.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OAG19234.1 - 0.0027 18.0 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OAG19234.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OAG19234.1 - 0.012 15.6 0.1 0.037 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG19234.1 - 0.02 15.3 0.1 0.033 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OAG19234.1 - 0.026 14.3 0.1 0.061 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG19234.1 - 0.026 15.0 0.1 0.037 14.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 OAG19234.1 - 0.038 13.4 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 OAG19234.1 - 0.068 13.3 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 OAG19234.1 - 0.098 12.2 0.1 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 OAG19234.1 - 0.11 12.3 0.6 0.18 11.6 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 OAG19234.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Torus PF16131.5 OAG19235.1 - 0.69 10.6 6.8 0.29 11.9 0.1 2.9 1 1 1 3 3 3 0 Torus domain zf-CCCH_2 PF14608.6 OAG19235.1 - 9.1 6.9 13.9 20 5.8 0.7 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SUI1 PF01253.22 OAG19236.1 - 2.1e-23 82.7 0.0 5.6e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAG19236.1 - 6.5e-07 30.0 0.1 1.4e-05 25.7 0.1 2.6 1 1 0 1 1 1 1 Pre-PUA-like domain SWIB PF02201.18 OAG19236.1 - 0.00037 20.3 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.9 OAG19236.1 - 0.0008 19.3 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein DUF373 PF04123.13 OAG19237.1 - 6.9 6.0 8.1 0.88 8.9 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) 4HBT_2 PF13279.6 OAG19238.1 - 0.00014 22.4 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PARP PF00644.20 OAG19240.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain E3_UbLigase_EDD PF11547.8 OAG19240.1 - 0.17 11.6 0.4 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Bim_N PF06773.11 OAG19242.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Bim protein N-terminus E1-E2_ATPase PF00122.20 OAG19244.1 - 2.7e-34 118.3 4.1 2.7e-34 118.3 4.1 4.2 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 OAG19244.1 - 2.3e-16 60.7 0.1 5.5e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG19244.1 - 1.5e-12 47.0 1.0 2e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG19244.1 - 0.0093 15.7 0.1 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 OAG19245.1 - 5e-28 98.0 30.7 5e-28 98.0 30.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG19245.1 - 5.3e-14 51.9 6.7 5.3e-14 51.9 6.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MBOAT PF03062.19 OAG19245.1 - 0.0033 16.8 1.1 0.0056 16.1 1.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.19 OAG19246.1 - 2.9e-150 500.4 0.0 1.1e-149 498.5 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 OAG19247.1 - 1.5e-26 93.1 3.1 1.5e-26 93.1 3.1 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 OAG19247.1 - 5.6e-07 29.3 0.1 0.072 13.4 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 OAG19247.1 - 1.1e-06 29.0 0.4 5.1e-05 23.7 0.1 3.0 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 OAG19247.1 - 1.2e-05 25.6 0.5 3.5e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 OAG19247.1 - 0.00012 22.0 0.1 0.23 11.6 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat PAC3 PF10178.9 OAG19248.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 CobW_C PF07683.14 OAG19248.1 - 0.05 13.5 0.0 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain YopE_N PF09020.10 OAG19248.1 - 0.087 13.1 0.7 0.2 11.9 0.7 1.6 1 0 0 1 1 1 0 YopE, N terminal HA2 PF04408.23 OAG19249.1 - 2.5e-20 72.7 0.1 2.5e-20 72.7 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG19249.1 - 4.6e-13 49.5 0.0 1.2e-11 44.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAG19249.1 - 4.1e-09 36.7 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAG19249.1 - 1e-08 35.2 0.1 2.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG19249.1 - 0.00024 21.4 0.0 0.00098 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OAG19249.1 - 0.0013 18.8 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG19249.1 - 0.0026 18.1 0.1 0.0054 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG19249.1 - 0.016 14.9 0.2 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG19249.1 - 0.036 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 OAG19249.1 - 0.04 13.0 0.0 0.086 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 OAG19249.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 OAG19250.1 - 1.4e-79 268.1 24.8 1.6e-79 267.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19250.1 - 1.8e-16 60.0 28.6 1.8e-16 60.0 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG19250.1 - 0.0025 16.3 0.9 0.0025 16.3 0.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_25 PF13649.6 OAG19251.1 - 1.8e-07 31.7 0.0 7.4e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG19251.1 - 6.7e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG19251.1 - 0.0001 21.9 0.1 0.0015 18.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OAG19251.1 - 0.00022 21.8 0.0 0.00091 19.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG19251.1 - 0.00035 20.0 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmC_N PF17827.1 OAG19251.1 - 0.00094 19.7 0.6 0.00094 19.7 0.6 2.3 2 0 0 2 2 2 1 PrmC N-terminal domain N6_Mtase PF02384.16 OAG19251.1 - 0.0038 16.5 0.0 0.0072 15.6 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase T2SSM PF04612.12 OAG19251.1 - 0.0071 16.4 0.5 0.079 13.0 0.5 2.2 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M Methyltransf_23 PF13489.6 OAG19251.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 OAG19251.1 - 0.021 14.1 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_32 PF13679.6 OAG19251.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 OAG19251.1 - 0.026 14.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 OAG19251.1 - 0.051 14.3 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OAG19251.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MIP PF00230.20 OAG19253.1 - 5.5e-47 160.4 16.2 6.7e-47 160.1 16.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.21 OAG19254.1 - 1e-11 44.7 6.1 1e-11 44.7 6.1 1.9 2 1 0 2 2 2 1 PAP2 superfamily UbiA PF01040.18 OAG19254.1 - 0.0003 20.2 9.7 0.0016 17.8 6.2 2.0 2 0 0 2 2 2 2 UbiA prenyltransferase family Virul_fac_BrkB PF03631.15 OAG19254.1 - 0.00045 19.9 1.2 0.00063 19.4 1.2 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF212 PF02681.14 OAG19254.1 - 0.00095 19.3 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 2 Divergent PAP2 family IBR PF01485.21 OAG19255.1 - 7.1e-21 74.2 39.2 2.3e-14 53.4 1.4 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 OAG19255.1 - 7.4e-17 61.7 0.2 1.6e-16 60.6 0.2 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 OAG19255.1 - 0.0015 18.4 10.5 0.0015 18.4 10.5 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG19255.1 - 0.0015 18.2 5.9 0.0015 18.2 5.9 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 OAG19255.1 - 0.006 16.5 12.3 0.006 16.5 12.3 4.0 2 2 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG19255.1 - 0.016 15.3 7.8 0.016 15.3 7.8 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAG19255.1 - 0.019 15.3 10.4 0.019 15.3 10.4 4.4 3 1 1 4 4 4 0 Ring finger domain Pro_isomerase PF00160.21 OAG19256.1 - 4.3e-50 170.1 0.1 5.5e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HsbA PF12296.8 OAG19257.1 - 1.6e-19 70.5 0.8 2.6e-19 69.8 0.8 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Amino_oxidase PF01593.24 OAG19258.1 - 3.2e-36 125.6 0.0 3.8e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Acetyltransf_1 PF00583.25 OAG19260.1 - 4e-16 59.3 0.0 5.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG19260.1 - 1.8e-07 31.5 0.0 3.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG19260.1 - 9.4e-07 28.8 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG19260.1 - 0.00033 20.6 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 OAG19260.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 OAG19260.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG19260.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 OAG19261.1 - 7e-06 26.0 0.7 2.4e-05 24.3 0.7 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_2 PF12796.7 OAG19262.1 - 5e-12 46.2 0.4 1.4e-05 25.5 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG19262.1 - 5.1e-10 39.7 0.4 9e-05 23.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG19262.1 - 1.6e-09 37.7 1.9 0.091 13.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OAG19262.1 - 1.3e-08 34.4 3.3 0.054 14.1 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG19262.1 - 7.4e-07 29.3 1.5 0.027 14.8 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) KilA-N PF04383.13 OAG19262.1 - 0.00086 19.1 2.1 0.0045 16.8 0.2 2.6 2 1 0 2 2 2 1 KilA-N domain BSP PF04450.12 OAG19265.1 - 6.7e-75 251.4 0.0 7.9e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 OAG19265.1 - 0.0017 18.2 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 OAG19265.1 - 0.015 15.6 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Effector protein Peptidase_M1 PF01433.20 OAG19265.1 - 0.028 14.0 0.5 0.041 13.4 0.5 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain Aspzincin_M35 PF14521.6 OAG19265.1 - 0.068 13.7 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase HAD_2 PF13419.6 OAG19266.1 - 1e-11 45.3 0.1 1.4e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG19266.1 - 1.3e-07 32.2 0.0 5.4e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG19266.1 - 0.0055 16.7 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like 5_nucleotid PF05761.14 OAG19266.1 - 0.026 13.4 0.2 0.17 10.7 0.2 1.9 1 1 1 2 2 2 0 5' nucleotidase family Draxin PF15550.6 OAG19267.1 - 1.5 8.6 8.5 0.11 12.3 2.3 2.1 2 0 0 2 2 2 0 Draxin KH_1 PF00013.29 OAG19268.1 - 3.7e-32 110.0 0.3 2.4e-07 30.4 0.0 5.9 6 0 0 6 6 6 4 KH domain GYF PF02213.16 OAG19270.1 - 7.3e-17 60.8 0.1 1.5e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAG19270.1 - 0.00099 18.9 0.0 0.0034 17.2 0.0 2.0 1 0 0 1 1 1 1 GYF domain 2 Homeodomain PF00046.29 OAG19270.1 - 0.3 10.9 3.8 0.73 9.7 3.8 1.6 1 0 0 1 1 1 0 Homeodomain NOA36 PF06524.12 OAG19271.1 - 5 6.3 6.5 10 5.4 4.3 2.0 2 0 0 2 2 2 0 NOA36 protein MFS_1 PF07690.16 OAG19272.1 - 4e-33 114.8 25.1 5.4e-33 114.4 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 OAG19272.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.7 2 1 0 2 2 2 0 VIT family SNARE_assoc PF09335.11 OAG19273.1 - 6.6e-19 68.6 9.0 6.6e-19 68.6 9.0 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein YrhC PF14143.6 OAG19273.1 - 0.0069 16.4 0.5 0.027 14.6 0.5 2.1 1 0 0 1 1 1 1 YrhC-like protein Phage_holin_3_6 PF07332.11 OAG19273.1 - 0.038 14.0 12.6 0.24 11.4 1.4 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Prok-RING_4 PF14447.6 OAG19275.1 - 0.0001 22.1 4.5 0.01 15.7 1.5 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG19275.1 - 0.0015 18.3 5.3 0.08 12.8 1.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG19275.1 - 0.0022 17.8 4.2 0.0026 17.6 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG19275.1 - 0.026 14.9 8.6 0.24 11.8 8.6 2.1 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAG19275.1 - 0.047 13.5 5.5 0.053 13.4 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG19275.1 - 0.11 12.4 3.7 1.9 8.3 0.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OAG19275.1 - 0.17 11.9 6.6 0.75 9.8 6.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG19275.1 - 0.61 10.2 4.9 0.15 12.1 1.2 1.8 2 0 0 2 2 2 0 RING-type zinc-finger IBR PF01485.21 OAG19275.1 - 2 8.7 6.5 0.52 10.6 2.2 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LtrA PF06772.11 OAG19276.1 - 3.1e-24 85.9 33.0 8.4e-24 84.4 26.0 2.3 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2567 PF10821.8 OAG19276.1 - 0.0028 17.8 2.2 0.0028 17.8 2.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2567) AA_permease PF00324.21 OAG19279.1 - 2e-98 330.1 28.4 2.2e-98 329.9 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG19279.1 - 1.8e-27 96.3 30.9 2.2e-27 96.0 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease GATase_4 PF13230.6 OAG19280.1 - 1.3e-11 43.9 0.0 9.6e-11 41.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAG19280.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG19280.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF4448 PF14610.6 OAG19281.1 - 0.0038 17.0 0.0 0.0064 16.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Gram_pos_anchor PF00746.21 OAG19281.1 - 0.019 14.9 2.6 0.019 14.9 2.6 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Cation_ATPase_C PF00689.21 OAG19281.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2613 PF11021.8 OAG19281.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Syndecan PF01034.20 OAG19281.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain AJAP1_PANP_C PF15298.6 OAG19281.1 - 4.4 7.5 9.4 8.7 6.5 9.4 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ABC_membrane PF00664.23 OAG19282.1 - 8.4e-96 320.8 34.8 8.3e-50 170.0 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG19282.1 - 2.8e-65 219.0 0.0 6.8e-32 110.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG19282.1 - 7.2e-15 55.0 3.7 2.4e-05 23.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAG19282.1 - 2.3e-09 36.6 2.7 0.00019 20.4 0.1 2.8 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 OAG19282.1 - 2.1e-08 34.5 1.0 0.023 15.0 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG19282.1 - 3.3e-08 34.1 1.9 0.01 16.2 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG19282.1 - 6.4e-07 29.5 0.1 0.18 11.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG19282.1 - 7.3e-07 29.2 0.0 0.077 12.9 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAG19282.1 - 1.7e-06 27.7 3.1 0.011 15.5 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG19282.1 - 2.6e-05 23.9 0.6 0.39 10.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAG19282.1 - 4.7e-05 22.8 0.1 0.012 14.9 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 OAG19282.1 - 5.7e-05 22.9 2.9 0.17 11.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 OAG19282.1 - 0.00015 21.9 3.1 0.51 10.6 0.4 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAG19282.1 - 0.00044 20.3 0.5 2.1 8.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 OAG19282.1 - 0.00058 19.7 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 OAG19282.1 - 0.0037 17.8 0.1 2.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG19282.1 - 0.0044 17.3 0.5 0.6 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAG19282.1 - 0.0045 16.9 0.4 0.32 10.9 0.1 3.1 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAG19282.1 - 0.0074 16.5 0.1 8.1 6.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OAG19282.1 - 0.013 15.2 0.6 2.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 OAG19282.1 - 0.017 14.3 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 OAG19282.1 - 0.026 14.6 0.4 9.3 6.3 0.2 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAG19282.1 - 0.037 14.5 0.2 8.7 6.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG19282.1 - 0.042 13.4 0.1 6.1 6.3 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG19282.1 - 0.048 14.0 0.1 4.9 7.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 OAG19282.1 - 0.061 13.2 0.1 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 OAG19282.1 - 0.089 11.9 0.1 14 4.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 OAG19282.1 - 0.11 11.7 0.3 3 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 OAG19282.1 - 0.12 12.3 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Synapsin_N PF10581.9 OAG19282.1 - 0.14 12.2 0.0 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Synapsin N-terminal AAA PF00004.29 OAG19282.1 - 0.15 12.5 4.1 75 3.8 0.1 4.4 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAG19282.1 - 0.17 12.0 2.2 13 5.9 0.0 3.3 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAG19282.1 - 0.28 10.9 0.9 18 4.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 OAG19282.1 - 0.3 10.8 1.9 21 4.8 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 OAG19282.1 - 0.66 9.6 2.7 22 4.6 0.0 3.0 4 1 0 4 4 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Fungal_trans PF04082.18 OAG19283.1 - 1.2e-13 50.7 1.9 1.4e-13 50.5 0.3 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19283.1 - 6.2e-09 35.8 13.4 1.2e-08 34.9 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 OAG19283.1 - 0.031 14.7 0.2 0.068 13.6 0.2 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3328 PF11807.8 OAG19284.1 - 8.2e-56 189.2 0.5 9.8e-56 189.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SicP-binding PF09119.10 OAG19285.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 SicP binding CAP_N PF01213.19 OAG19286.1 - 1.1e-105 353.6 0.1 1.1e-105 353.6 0.1 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAG19286.1 - 1.1e-61 207.1 0.4 1.4e-61 206.7 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAG19286.1 - 0.025 14.3 2.3 0.037 13.7 1.0 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.24 OAG19287.1 - 5.2e-13 49.0 0.0 7.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1616 PF07760.11 OAG19288.1 - 0.17 11.3 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) dsrm PF00035.26 OAG19289.1 - 1.8e-07 31.8 0.0 3.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 OAG19289.1 - 0.00077 19.6 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG19289.1 - 0.0013 19.4 0.0 0.0041 17.7 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Pkinase PF00069.25 OAG19290.1 - 1.2e-20 74.0 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19290.1 - 4.5e-16 58.9 0.0 6.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG19290.1 - 0.031 13.7 0.7 0.39 10.0 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_5 PF00266.19 OAG19293.1 - 4.5e-20 71.9 0.0 8.8e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG19293.1 - 4.7e-07 29.3 0.0 7.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_2 PF00890.24 OAG19294.1 - 1.3e-43 149.6 0.3 5.4e-43 147.6 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG19294.1 - 4.1e-12 46.3 0.3 4.1e-12 46.3 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG19294.1 - 1.6e-09 37.7 3.0 1.1e-07 31.5 3.0 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG19294.1 - 1.8e-06 26.9 0.9 0.00037 19.3 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG19294.1 - 6.9e-06 25.5 0.0 0.00046 19.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG19294.1 - 2.3e-05 24.9 0.6 0.31 11.6 0.1 3.3 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG19294.1 - 0.00019 20.7 2.9 0.00019 20.6 0.8 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG19294.1 - 0.001 19.3 0.5 0.0037 17.5 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 OAG19294.1 - 0.0016 17.9 0.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_3 PF01494.19 OAG19294.1 - 0.0017 17.7 0.3 0.0037 16.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG19294.1 - 0.0065 15.6 0.1 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 OAG19294.1 - 0.0074 15.6 0.1 0.018 14.3 0.1 1.7 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 OAG19294.1 - 0.0088 15.4 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OAG19294.1 - 0.01 16.3 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAG19294.1 - 0.016 14.4 1.9 0.03 13.6 0.2 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_G PF04718.15 OAG19294.1 - 0.016 16.0 0.0 0.051 14.4 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit Trp_halogenase PF04820.14 OAG19294.1 - 0.071 11.9 0.2 0.17 10.7 0.2 1.6 1 0 0 1 1 1 0 Tryptophan halogenase PALP PF00291.25 OAG19294.1 - 0.12 11.7 2.2 5.4 6.3 0.3 2.9 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 OAG19294.1 - 0.13 12.5 0.0 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Eaf7 PF07904.13 OAG19295.1 - 2.8e-28 98.4 0.2 2.8e-28 98.4 0.2 2.1 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 OAG19295.1 - 0.17 11.2 4.7 0.31 10.3 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 OAG19295.1 - 0.19 11.1 6.3 0.3 10.5 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 OAG19295.1 - 0.4 10.3 6.9 0.89 9.2 6.9 1.5 1 0 0 1 1 1 0 FAM176 family FXMRP1_C_core PF12235.8 OAG19295.1 - 0.76 10.4 7.9 1.4 9.6 7.9 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal AIM3 PF17096.5 OAG19295.1 - 0.8 10.7 9.2 2.2 9.2 9.2 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 GOLD_2 PF13897.6 OAG19295.1 - 1.1 9.8 4.4 2 8.9 4.4 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DDHD PF02862.17 OAG19295.1 - 5.8 7.0 8.7 35 4.5 8.7 1.9 1 1 0 1 1 1 0 DDHD domain GCP_C_terminal PF04130.13 OAG19296.1 - 9.9e-73 245.3 2.3 2.9e-72 243.8 0.3 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG19296.1 - 1.1e-31 110.7 0.5 2.3e-31 109.6 0.5 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF3658 PF12395.8 OAG19296.1 - 0.0033 17.3 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function Fructosamin_kin PF03881.14 OAG19298.1 - 4.2e-33 114.8 0.0 5.2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG19298.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLASP_N PF12348.8 OAG19299.1 - 3e-119 396.6 3.8 3.1e-85 285.4 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 OAG19299.1 - 0.0062 16.7 2.4 50 4.5 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 OAG19299.1 - 0.17 11.9 0.2 19 5.3 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Thi4 PF01946.17 OAG19300.1 - 4.9e-115 382.7 0.0 6.2e-115 382.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG19300.1 - 9.9e-07 28.6 0.5 4.8e-06 26.4 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG19300.1 - 6.6e-05 22.3 0.1 9.5e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG19300.1 - 0.00015 21.0 2.4 0.0015 17.7 1.0 2.8 3 1 1 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 OAG19300.1 - 0.00042 20.5 1.1 0.0011 19.2 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG19300.1 - 0.00061 18.9 0.6 0.00061 18.9 0.6 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG19300.1 - 0.00074 19.5 1.0 0.0013 18.7 0.1 1.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG19300.1 - 0.0072 15.7 0.1 0.0097 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG19300.1 - 0.038 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG19300.1 - 0.11 11.1 0.9 0.21 10.3 0.9 1.4 1 0 0 1 1 1 0 HI0933-like protein N-SET PF11764.8 OAG19300.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N RhoGAP PF00620.27 OAG19301.1 - 1.2e-46 158.3 0.0 4.9e-46 156.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAG19301.1 - 9.6e-14 51.4 18.5 1.9e-09 37.6 1.7 2.4 2 0 0 2 2 2 2 LIM domain ABC_tran_CTD PF16326.5 OAG19301.1 - 0.048 13.9 11.9 0.14 12.4 3.9 3.1 1 1 0 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 OAG19301.1 - 0.053 13.6 8.8 0.14 12.2 8.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Desulfoferrod_N PF06397.12 OAG19301.1 - 0.53 9.9 12.9 9.6 5.9 1.9 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF2757 PF10955.8 OAG19301.1 - 1.1 9.5 7.7 5.5 7.3 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) DivIC PF04977.15 OAG19301.1 - 1.9 8.3 8.6 3.7 7.4 0.1 4.0 3 1 1 4 4 4 0 Septum formation initiator DUF3450 PF11932.8 OAG19301.1 - 2.4 7.4 10.6 0.61 9.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TBCA PF02970.16 OAG19301.1 - 4 7.8 9.6 8.5 6.8 6.9 2.6 1 1 1 2 2 2 0 Tubulin binding cofactor A Zn-ribbon_8 PF09723.10 OAG19301.1 - 6.1 7.0 19.7 1.1 9.4 1.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain KLRAQ PF10205.9 OAG19301.1 - 6.6 7.0 13.0 0.82 9.9 0.5 3.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Seryl_tRNA_N PF02403.22 OAG19301.1 - 6.7 7.0 17.9 9.2 6.6 5.1 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain zf-ribbon_3 PF13248.6 OAG19301.1 - 7.5 6.1 20.1 0.81 9.2 0.0 4.5 5 1 0 5 5 5 0 zinc-ribbon domain DUF5353 PF17304.2 OAG19302.1 - 2.2e-30 104.2 3.2 2.8e-30 103.8 3.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5353) ETRAMP PF09716.10 OAG19302.1 - 0.05 13.7 0.4 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CD99L2 PF12301.8 OAG19302.1 - 0.081 13.2 2.5 0.12 12.6 2.5 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 CHCH PF06747.13 OAG19303.1 - 1.4e-06 28.3 5.3 2.4e-06 27.5 5.3 1.4 1 0 0 1 1 1 1 CHCH domain PepSY_TM PF03929.16 OAG19303.1 - 0.1 12.2 2.3 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 PepSY-associated TM region GCK PF07802.11 OAG19303.1 - 0.15 12.5 2.1 0.33 11.4 2.1 1.6 1 0 0 1 1 1 0 GCK domain SWIRM PF04433.17 OAG19304.1 - 8.1e-29 99.8 0.0 1.5e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OAG19304.1 - 1.6e-27 95.3 5.2 3e-27 94.4 5.2 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAG19304.1 - 6e-12 45.6 0.7 1e-11 44.8 0.7 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG19304.1 - 2.6e-07 30.8 0.5 5.9e-07 29.6 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG19304.1 - 0.0044 16.9 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OAG19304.1 - 0.0045 17.2 0.2 0.012 15.8 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ETF PF01012.21 OAG19305.1 - 5.6e-43 146.9 0.4 1.1e-42 146.0 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAG19305.1 - 3.4e-33 113.5 0.1 7.7e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ion_trans_2 PF07885.16 OAG19306.1 - 1.8e-26 91.9 16.5 6.5e-16 58.1 6.2 3.8 4 1 1 5 5 5 2 Ion channel Lig_chan PF00060.26 OAG19306.1 - 0.016 15.1 6.9 0.054 13.3 2.7 3.0 2 1 0 2 2 2 0 Ligand-gated ion channel ABC_membrane PF00664.23 OAG19307.1 - 9.6e-83 278.0 35.7 1.2e-41 143.2 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG19307.1 - 8.6e-64 214.2 0.0 6e-35 120.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG19307.1 - 8e-14 51.6 7.2 2.3e-07 30.5 2.3 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG19307.1 - 6.7e-10 39.4 0.2 0.0007 19.9 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OAG19307.1 - 1.6e-07 31.9 1.4 0.011 16.2 0.2 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAG19307.1 - 1.6e-07 31.0 0.6 0.00092 18.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG19307.1 - 2.4e-07 30.8 0.2 1.1 9.0 0.0 3.7 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG19307.1 - 3.6e-06 26.8 0.5 0.2 11.4 0.0 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAG19307.1 - 4.9e-06 26.6 0.0 0.17 11.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 OAG19307.1 - 1.1e-05 26.1 0.0 0.0011 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAG19307.1 - 0.00012 22.1 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 OAG19307.1 - 0.00019 21.3 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAG19307.1 - 0.00072 20.1 0.0 0.69 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 OAG19307.1 - 0.00078 18.4 0.2 1.7 7.4 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 OAG19307.1 - 0.00092 19.2 0.0 3.1 7.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAG19307.1 - 0.0012 18.5 0.1 2.9 7.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 OAG19307.1 - 0.0027 17.9 1.7 0.82 9.9 0.2 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 OAG19307.1 - 0.0058 16.8 0.6 4.9 7.2 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_33 PF13671.6 OAG19307.1 - 0.0058 16.8 0.1 2.3 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG19307.1 - 0.0067 16.8 5.6 6.6 7.2 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG19307.1 - 0.0074 15.6 0.6 0.58 9.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 OAG19307.1 - 0.0081 16.5 0.0 8 6.9 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 OAG19307.1 - 0.0097 16.2 1.3 0.35 11.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 OAG19307.1 - 0.011 15.5 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 OAG19307.1 - 0.012 15.4 0.4 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 OAG19307.1 - 0.014 15.1 0.1 2.8 7.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OAG19307.1 - 0.018 14.2 0.2 7 5.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 OAG19307.1 - 0.019 14.5 0.0 8.7 5.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAG19307.1 - 0.021 14.8 0.0 19 5.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain CRCB PF02537.15 OAG19307.1 - 0.033 14.5 0.5 0.033 14.5 0.5 4.1 5 1 0 5 5 2 0 CrcB-like protein, Camphor Resistance (CrcB) G-alpha PF00503.20 OAG19307.1 - 0.052 12.7 0.1 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG19307.1 - 0.055 13.6 0.1 6.6 6.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAG19307.1 - 0.066 12.9 0.6 13 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.20 OAG19308.1 - 1e-14 54.9 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF4210 PF13915.6 OAG19309.1 - 2.6e-33 114.4 0.1 6.6e-33 113.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAG19309.1 - 3.4e-24 84.7 0.9 7.4e-24 83.7 0.9 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 OAG19310.1 - 0.00042 20.4 27.2 0.0021 18.1 27.2 1.9 1 1 0 1 1 1 1 rRNA processing ATP-synt_E PF05680.12 OAG19310.1 - 2.5 8.5 15.7 2.6 8.5 4.2 2.5 2 0 0 2 2 2 0 ATP synthase E chain Presenilin PF01080.17 OAG19310.1 - 2.6 6.7 9.3 3.3 6.4 9.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 OAG19310.1 - 6.6 5.4 12.8 7.6 5.2 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Trypan_PARP PF05887.11 OAG19310.1 - 9.4 6.2 23.4 1.8 8.5 18.8 2.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-binding PF00249.31 OAG19311.1 - 1e-35 121.7 11.3 2.1e-14 53.4 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG19311.1 - 8.9e-28 96.3 4.4 1.5e-13 50.8 0.5 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG19311.1 - 1.4e-05 24.9 0.3 0.16 11.9 0.0 2.8 1 1 2 3 3 3 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OAG19311.1 - 0.0014 18.9 1.9 5.4 7.4 0.1 3.5 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 OAG19311.1 - 0.0027 17.9 0.2 0.41 10.9 0.0 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 OAG19311.1 - 0.075 13.1 0.2 3.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AcetylCoA_hydro PF02550.15 OAG19312.1 - 1.3e-48 165.6 0.0 2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 OAG19312.1 - 2.3e-40 138.0 0.0 4.7e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Whi5 PF08528.11 OAG19312.1 - 5.6e-13 48.2 0.2 9.9e-13 47.4 0.2 1.4 1 0 0 1 1 1 1 Whi5 like Palm_thioest PF02089.15 OAG19313.1 - 2.4e-74 250.2 0.0 2.9e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 OAG19313.1 - 0.039 13.5 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) Ribosomal_L1 PF00687.21 OAG19314.1 - 5.5e-59 199.3 4.1 5.5e-59 199.3 4.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family zf-RRN7 PF11781.8 OAG19316.1 - 4.1e-10 39.2 3.6 6.7e-10 38.5 3.6 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 OAG19317.1 - 2.4e-28 98.0 1.5 3.3e-28 97.6 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OAG19317.1 - 0.041 13.9 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 OAG19318.1 - 5e-129 431.3 0.0 5.8e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OAG19318.1 - 6.7e-05 21.5 0.5 9e-05 21.1 0.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Spc7 PF08317.11 OAG19318.1 - 0.008 15.1 1.6 0.015 14.2 1.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Mer2 PF09074.10 OAG19318.1 - 0.048 13.5 0.8 2.9 7.7 0.3 2.7 3 0 0 3 3 3 0 Mer2 GAS PF13851.6 OAG19318.1 - 0.075 12.4 1.9 0.15 11.4 1.9 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAG19318.1 - 0.079 13.0 0.5 0.2 11.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2443 PF10398.9 OAG19318.1 - 0.11 12.6 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF4795 PF16043.5 OAG19318.1 - 0.12 12.0 1.6 0.37 10.4 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Med4 PF10018.9 OAG19318.1 - 0.14 11.8 1.7 0.29 10.8 1.7 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Xrn1_D3 PF18194.1 OAG19318.1 - 0.15 12.2 2.4 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 ABC_tran_CTD PF16326.5 OAG19318.1 - 0.16 12.3 4.5 5.3 7.4 0.5 3.3 3 1 0 3 3 3 0 ABC transporter C-terminal domain ATG16 PF08614.11 OAG19318.1 - 3.9 7.7 7.4 0.67 10.1 0.7 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1993 PF09351.10 OAG19319.1 - 1.1e-30 106.9 0.0 1.2e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) 2OG-FeII_Oxy_3 PF13640.6 OAG19320.1 - 3.6e-08 34.2 0.0 6.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pyr_redox_2 PF07992.14 OAG19322.1 - 7.6e-09 35.2 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG19322.1 - 0.0081 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG19322.1 - 0.044 13.8 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG19322.1 - 0.06 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein CRISPR_Cas6 PF10040.9 OAG19323.1 - 0.18 12.4 2.2 7.9 7.2 0.1 4.0 4 0 0 4 4 4 0 CRISPR-associated endoribonuclease Cas6 TssN PF17555.2 OAG19323.1 - 1 8.7 2.6 2 7.8 2.6 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4083 PF13314.6 OAG19325.1 - 0.0015 18.4 0.1 0.0037 17.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) EphA2_TM PF14575.6 OAG19325.1 - 0.01 16.7 0.0 0.019 15.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OAG19325.1 - 0.082 12.8 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OAG19325.1 - 0.11 12.2 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1996 PF09362.10 OAG19327.1 - 3.1e-80 269.5 0.2 3.8e-80 269.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.16 OAG19328.1 - 8.6e-25 87.4 58.0 2e-19 69.8 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CAS_C PF12026.8 OAG19329.1 - 0.22 11.6 0.4 0.28 11.3 0.4 1.1 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Peptidase_M28 PF04389.17 OAG19330.1 - 1.1e-29 103.6 0.1 3.2e-29 102.1 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG19330.1 - 8.8e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OAG19330.1 - 0.0047 16.0 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase V-SNARE_C PF12352.8 OAG19331.1 - 2.7e-14 53.2 0.8 1.2e-13 51.1 0.2 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAG19331.1 - 0.00065 19.6 0.1 0.005 16.7 0.0 2.3 2 1 1 3 3 3 1 Sec20 WEMBL PF05701.11 OAG19331.1 - 0.0069 15.1 2.0 0.01 14.6 2.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light HBM PF16591.5 OAG19331.1 - 0.034 13.6 2.1 0.06 12.8 2.1 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain KxDL PF10241.9 OAG19331.1 - 0.039 14.2 6.3 0.36 11.1 1.9 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein PilJ PF13675.6 OAG19331.1 - 0.042 13.9 2.5 0.078 13.0 2.5 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF16 PF01519.16 OAG19331.1 - 0.081 13.4 1.3 0.7 10.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 PEPcase PF00311.17 OAG19331.1 - 0.2 9.7 1.2 0.25 9.4 1.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase PSI_PsaF PF02507.15 OAG19331.1 - 0.59 9.9 2.3 5 6.9 1.6 2.1 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III EMP24_GP25L PF01105.24 OAG19331.1 - 1.1 9.2 4.4 0.21 11.5 0.6 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD T2SSM PF04612.12 OAG19331.1 - 3.2 7.8 8.6 1.2 9.2 1.3 2.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M DUF4407 PF14362.6 OAG19331.1 - 7.1 5.9 6.2 3 7.1 2.7 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2789 PF10982.8 OAG19333.1 - 0.042 14.0 0.4 0.042 14.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) REV1_C PF16727.5 OAG19333.1 - 0.13 12.7 0.3 1.9 9.0 0.0 2.2 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Pyr_redox_2 PF07992.14 OAG19334.1 - 3.3e-43 148.0 0.4 5.2e-43 147.4 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAG19334.1 - 1.1e-19 70.5 0.0 2.3e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske PF00355.26 OAG19334.1 - 2.6e-16 59.3 0.3 1.1e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAG19334.1 - 9.3e-16 58.2 6.4 1.5e-14 54.3 0.8 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 OAG19334.1 - 4.3e-14 52.6 5.7 3.3e-11 43.3 5.3 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 OAG19334.1 - 5.6e-14 51.9 0.0 2.1e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAG19334.1 - 1.1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 OAG19334.1 - 1.7e-05 24.7 0.2 0.079 12.9 0.0 3.6 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OAG19334.1 - 0.00024 21.1 0.1 1.3 9.0 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 OAG19334.1 - 0.017 14.2 0.5 0.61 9.1 0.3 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG19334.1 - 0.086 13.1 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG19334.1 - 0.16 11.1 0.0 0.82 8.7 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mo-co_dimer PF03404.16 OAG19335.1 - 1.7e-59 199.7 0.1 3.1e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 OAG19335.1 - 7.4e-53 178.7 0.0 1.5e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 OAG19335.1 - 1.3e-35 121.7 0.0 2.3e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG19335.1 - 1.2e-27 96.7 0.0 5.2e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAG19335.1 - 1.6e-20 73.0 0.0 3.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG19335.1 - 0.005 17.0 0.1 0.095 12.8 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain ResIII PF04851.15 OAG19337.1 - 8.8e-26 90.9 0.2 2.5e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG19337.1 - 9.9e-15 54.9 0.0 1.2e-13 51.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG19337.1 - 1.3e-12 47.8 0.1 3.5e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAG19337.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CAP_N PF01213.19 OAG19337.1 - 0.00015 21.4 3.1 0.00031 20.3 3.1 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF2075 PF09848.9 OAG19337.1 - 0.0057 15.9 1.1 0.0062 15.8 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PRIMA1 PF16101.5 OAG19337.1 - 0.0065 16.5 2.0 0.012 15.6 2.0 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 rve PF00665.26 OAG19337.1 - 0.0067 16.6 0.6 3.4 7.9 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain Protamine_like PF06382.11 OAG19337.1 - 0.0089 16.2 0.6 0.2 11.8 0.2 2.3 2 0 0 2 2 2 1 Protamine and protamine like SwrA PF17423.2 OAG19337.1 - 0.016 15.2 0.1 0.066 13.2 0.0 2.1 2 0 0 2 2 2 0 Swarming motility protein AAA_22 PF13401.6 OAG19337.1 - 0.034 14.4 0.1 0.34 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 OAG19337.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Mito_fiss_reg PF05308.11 OAG19337.1 - 0.6 10.2 5.7 0.22 11.6 2.2 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator UvrD-helicase PF00580.21 OAG19337.1 - 0.67 9.4 3.8 7.4 6.0 0.0 2.9 2 2 1 3 3 3 0 UvrD/REP helicase N-terminal domain Zn_clus PF00172.18 OAG19338.1 - 3e-07 30.4 10.1 5.2e-07 29.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 OAG19340.1 - 0.023 14.6 0.3 0.047 13.6 0.3 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAG19340.1 - 0.11 12.4 0.3 0.29 11.1 0.3 1.7 1 0 0 1 1 1 0 F-box domain DUF1003 PF06210.11 OAG19341.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Cnn_1N PF07989.11 OAG19342.1 - 0.0029 17.7 0.7 0.0088 16.2 0.0 2.0 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 OAG19342.1 - 0.031 14.1 2.4 0.081 12.8 2.4 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2046 PF09755.9 OAG19342.1 - 0.042 13.1 0.6 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) PKcGMP_CC PF16808.5 OAG19342.1 - 0.14 12.1 1.0 0.24 11.3 0.4 1.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 OAG19342.1 - 0.74 10.5 8.3 4.6 7.9 0.8 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 OAG19342.1 - 5.8 6.8 6.3 3.5 7.5 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator Sec62 PF03839.16 OAG19343.1 - 6.5e-77 257.9 0.9 6.5e-77 257.9 0.9 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4337 PF14235.6 OAG19343.1 - 0.035 14.2 0.0 0.035 14.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) SPATA3 PF15662.5 OAG19343.1 - 6.2 7.4 20.6 5.3 7.6 7.2 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Glyco_transf_41 PF13844.6 OAG19344.1 - 2.9e-106 355.7 0.1 7.9e-55 186.1 0.0 3.0 1 1 2 3 3 3 2 Glycosyl transferase family 41 TPR_2 PF07719.17 OAG19344.1 - 1.8e-13 49.4 20.8 0.013 15.5 0.1 6.1 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19344.1 - 2.4e-13 49.3 19.4 0.0016 18.2 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG19344.1 - 2.2e-11 43.3 19.5 0.00013 21.5 0.6 6.3 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.6 OAG19344.1 - 9.9e-11 41.0 10.7 0.017 15.3 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG19344.1 - 1.2e-09 38.4 9.8 8.8e-05 22.7 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG19344.1 - 1.3e-08 34.6 10.8 0.59 10.6 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19344.1 - 4e-07 30.4 12.1 0.00048 20.6 0.8 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG19344.1 - 5.7e-07 29.2 12.8 1 9.3 0.6 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG19344.1 - 5.2e-06 26.8 9.5 0.41 11.6 0.7 6.3 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG19344.1 - 2e-05 25.1 6.6 0.1 13.2 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG19344.1 - 0.00049 19.9 7.3 3.1 8.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 OAG19344.1 - 0.036 14.5 7.7 1.7 9.1 0.0 3.8 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TAF1_subA PF14929.6 OAG19344.1 - 0.11 11.9 0.4 0.23 10.8 0.4 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A HrpB1_HrpK PF09613.10 OAG19344.1 - 0.14 11.8 0.6 0.42 10.3 0.6 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 OAG19344.1 - 0.15 12.3 5.2 0.2 11.9 0.8 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 OAG19344.1 - 0.49 9.1 2.9 0.37 9.5 0.9 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat GIT_CC PF16559.5 OAG19345.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.7 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor RR_TM4-6 PF06459.12 OAG19345.1 - 0.62 9.9 12.0 0.78 9.5 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1690 PF07956.11 OAG19345.1 - 6.1 7.3 18.0 0.58 10.6 12.1 2.0 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) NUDIX_4 PF14815.6 OAG19346.1 - 7.6e-19 67.7 0.0 2.2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 OAG19346.1 - 9.4e-17 61.4 0.0 2.9e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG19346.1 - 0.013 15.3 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 OAG19346.1 - 3.1 8.2 9.5 0.81 10.1 5.0 2.4 2 1 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ammonium_transp PF00909.21 OAG19347.1 - 3.6e-98 328.9 18.8 4.1e-98 328.7 18.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SepZ PF06066.11 OAG19347.1 - 0.48 10.7 2.7 0.61 10.3 0.8 2.0 2 0 0 2 2 2 0 SepZ Fels1 PF05666.11 OAG19348.1 - 0.066 12.9 0.4 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Cutinase PF01083.22 OAG19349.1 - 5.7e-28 98.1 0.7 9.6e-28 97.3 0.7 1.4 1 0 0 1 1 1 1 Cutinase ETF_QO PF05187.13 OAG19349.1 - 0.0099 16.0 0.2 0.066 13.4 0.2 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PPR PF01535.20 OAG19349.1 - 0.017 15.3 0.5 11 6.5 0.0 3.1 3 0 0 3 3 3 0 PPR repeat DJ-1_PfpI PF01965.24 OAG19350.1 - 4.6e-12 46.1 0.0 1.1e-11 44.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG19350.1 - 1.3e-07 31.5 0.0 6.4e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like adh_short PF00106.25 OAG19351.1 - 8e-43 146.2 0.3 9.7e-43 145.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19351.1 - 1.4e-41 142.6 0.3 1.7e-41 142.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 OAG19351.1 - 0.0014 18.3 0.1 0.0031 17.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 OAG19351.1 - 0.004 17.1 0.6 0.012 15.5 0.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19351.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family PTP_tm PF18861.1 OAG19353.1 - 0.31 11.0 2.9 0.52 10.3 2.9 1.6 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Na_H_Exchanger PF00999.21 OAG19354.1 - 2.5e-38 131.9 21.5 3.5e-38 131.4 21.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAG19354.1 - 0.0052 16.8 1.8 0.032 14.3 0.7 2.9 2 0 0 2 2 2 1 YrhC-like protein HupE_UreJ PF04955.12 OAG19354.1 - 0.015 14.8 0.4 0.015 14.8 0.4 3.0 3 1 0 3 3 3 0 HupE / UreJ protein MCM PF00493.23 OAG19357.1 - 2.6e-96 321.0 0.1 5.4e-96 320.0 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG19357.1 - 1.8e-31 108.6 0.0 3.4e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG19357.1 - 6.6e-23 80.9 1.1 1.5e-22 79.8 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG19357.1 - 1.8e-12 47.8 0.0 5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG19357.1 - 1.3e-07 31.3 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG19357.1 - 0.0051 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG19357.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SLAIN PF15301.6 OAG19357.1 - 0.056 12.7 5.9 0.093 12.0 5.9 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family BUD22 PF09073.10 OAG19357.1 - 0.21 10.9 11.0 0.31 10.3 11.0 1.1 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 OAG19357.1 - 0.77 8.5 4.4 1.1 8.0 4.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain adh_short PF00106.25 OAG19358.1 - 2.5e-46 157.6 0.0 3.2e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19358.1 - 2.7e-32 112.2 0.0 3.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19358.1 - 2.3e-07 30.9 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG19358.1 - 0.00026 21.0 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG19358.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG19358.1 - 0.055 12.8 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 OAG19358.1 - 0.06 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Glyco_hydro_43 PF04616.14 OAG19359.1 - 3.1e-26 92.3 0.3 1.3e-25 90.3 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 PLDc_2 PF13091.6 OAG19360.1 - 5.4e-14 52.2 0.7 4.4e-06 26.6 0.0 4.0 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 OAG19360.1 - 1.4e-13 50.4 2.8 2.2e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PAXIP1_C PF15364.6 OAG19361.1 - 0.092 13.1 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein YpjP PF14005.6 OAG19361.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 YpjP-like protein CENP-L PF13092.6 OAG19362.1 - 3.7e-43 147.6 0.1 5.4e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HSP70 PF00012.20 OAG19363.1 - 2e-162 541.5 1.5 2e-162 541.5 1.5 2.3 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG19363.1 - 6.6e-14 51.5 0.1 9.9e-12 44.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2570 PF10828.8 OAG19363.1 - 4 7.3 8.3 1.4 8.8 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Fungal_trans_2 PF11951.8 OAG19364.1 - 3.9e-09 35.8 0.2 5.7e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19364.1 - 1.3e-05 25.2 3.4 3.9e-05 23.7 3.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BBE PF08031.12 OAG19365.1 - 4.9e-11 42.5 0.1 1.1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 OAG19365.1 - 4.6e-10 39.4 0.6 4.1e-09 36.3 0.6 2.4 1 1 0 1 1 1 1 FAD binding domain Phage_tail_APC PF16778.5 OAG19365.1 - 0.05 13.5 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Cytokin-bind PF09265.10 OAG19365.1 - 0.17 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding 2-oxoacid_dh PF00198.23 OAG19366.1 - 3.6e-71 239.3 0.2 4.5e-71 239.0 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG19366.1 - 5.5e-19 67.8 1.1 1.5e-18 66.4 1.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG19366.1 - 3.2e-12 46.6 0.4 9.5e-12 45.1 0.4 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 OAG19366.1 - 0.27 11.7 2.6 0.75 10.3 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) Sec7 PF01369.20 OAG19367.1 - 3e-68 229.1 0.5 1.7e-67 226.7 0.1 2.7 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 OAG19367.1 - 5.5e-42 143.3 0.8 5.5e-42 143.3 0.8 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAG19367.1 - 5.9e-37 125.4 13.5 9.6e-33 111.9 0.1 7.1 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 OAG19367.1 - 5.9e-20 71.7 6.5 1.8e-19 70.1 0.0 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Phage_tail_U PF06141.11 OAG19367.1 - 0.079 13.3 0.4 0.25 11.7 0.4 1.8 1 0 0 1 1 1 0 Phage minor tail protein U MRJP PF03022.16 OAG19368.1 - 8.7e-24 84.4 0.0 1.4e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OAG19368.1 - 0.087 12.4 0.0 0.32 10.5 0.0 1.9 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region La PF05383.17 OAG19369.1 - 8e-17 61.0 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OAG19369.1 - 0.00021 21.0 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim44 PF04280.15 OAG19369.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Tim44-like domain GRP PF07172.11 OAG19369.1 - 6.6 7.5 26.0 8.8 7.1 8.5 2.8 2 0 0 2 2 2 0 Glycine rich protein family S4 PF01479.25 OAG19370.1 - 1.7e-14 53.3 0.0 3.6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain MobB PF03205.14 OAG19370.1 - 0.052 13.5 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HBS1_N PF08938.10 OAG19370.1 - 0.08 13.3 0.7 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus DUF4404 PF14357.6 OAG19370.1 - 0.49 11.1 2.1 0.6 10.8 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4515 PF14988.6 OAG19371.1 - 0.0025 17.7 2.8 0.0059 16.5 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF1043 PF06295.12 OAG19371.1 - 0.17 11.9 2.8 0.46 10.5 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Paralemmin PF03285.15 OAG19371.1 - 0.41 10.2 4.1 0.34 10.4 1.8 1.9 2 0 0 2 2 2 0 Paralemmin DUF5082 PF16888.5 OAG19371.1 - 2.9 8.2 10.3 3.4 8.0 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phage_Mu_Gam PF07352.12 OAG19371.1 - 2.9 7.8 8.6 0.28 11.1 2.9 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF5320 PF17253.2 OAG19371.1 - 4.3 8.5 7.3 13 6.9 1.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) LSM PF01423.22 OAG19372.1 - 3.7e-15 55.3 0.0 5.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG19372.1 - 9.1e-05 22.5 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.6 OAG19372.1 - 0.058 14.0 8.9 0.077 13.6 8.9 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein DUF4023 PF13215.6 OAG19372.1 - 0.089 12.8 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) adh_short PF00106.25 OAG19373.1 - 1.2e-29 103.1 0.0 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19373.1 - 1.6e-23 83.5 0.0 2.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19373.1 - 0.00018 21.5 0.3 0.02 14.8 0.3 3.0 2 1 0 2 2 2 1 KR domain MFS_1 PF07690.16 OAG19374.1 - 1.5e-33 116.2 28.5 1.9e-33 115.8 28.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5422 PF17459.2 OAG19374.1 - 0.0046 17.2 1.0 0.0046 17.2 1.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5422) ADH_zinc_N PF00107.26 OAG19375.1 - 2.6e-19 69.5 1.0 4.2e-19 68.8 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG19375.1 - 7.1e-08 33.6 0.1 1.2e-07 32.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG19375.1 - 0.03 13.8 1.4 0.12 11.8 1.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Tnp_22_dsRBD PF17490.2 OAG19375.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain GFA PF04828.14 OAG19376.1 - 1.1e-21 76.9 0.5 1.8e-21 76.3 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.6 OAG19376.1 - 0.0065 16.8 0.2 0.37 11.2 0.0 2.3 2 0 0 2 2 2 1 Transposase-associated domain Herpes_gI PF01688.17 OAG19376.1 - 0.16 11.9 0.9 0.22 11.4 0.9 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I HalOD2 PF18547.1 OAG19376.1 - 0.31 11.0 3.5 3.4 7.6 0.1 2.9 3 0 0 3 3 3 0 Halobacterial output domain 2 Rpr2 PF04032.16 OAG19376.1 - 1.5 9.2 5.2 0.84 10.0 0.4 2.1 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.14 OAG19377.1 - 3.1e-21 75.5 0.5 4.8e-21 74.9 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 OAG19377.1 - 0.17 12.0 2.7 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.16 OAG19377.1 - 0.57 10.5 3.1 0.93 9.8 0.1 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nup35_RRM_2 PF14605.6 OAG19378.1 - 2e-06 27.7 0.0 5.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 OAG19378.1 - 2.9e-06 27.0 0.1 6.4e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 OAG19378.1 - 0.00014 22.1 0.1 0.00067 19.9 0.0 2.0 2 0 0 2 2 2 1 PWI domain RRM_occluded PF16842.5 OAG19378.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif PKcGMP_CC PF16808.5 OAG19378.1 - 0.012 15.4 5.0 0.03 14.2 5.0 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RRM_3 PF08777.11 OAG19378.1 - 0.024 14.7 1.4 0.024 14.7 1.4 2.2 1 1 1 2 2 2 0 RNA binding motif DUF1330 PF07045.11 OAG19378.1 - 0.079 13.3 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DUF641 PF04859.12 OAG19378.1 - 0.15 12.4 4.6 0.28 11.5 4.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) AAA_23 PF13476.6 OAG19378.1 - 0.22 12.0 2.9 0.41 11.1 2.9 1.4 1 0 0 1 1 1 0 AAA domain HIP1_clath_bdg PF16515.5 OAG19378.1 - 0.33 11.6 9.3 0.65 10.6 9.3 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PHM7_cyt PF14703.6 OAG19378.1 - 0.67 10.2 0.0 0.67 10.2 0.0 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter AAA_13 PF13166.6 OAG19378.1 - 0.79 8.3 6.9 1.2 7.7 6.9 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 OAG19379.1 - 1.9e-66 223.4 0.2 2.7e-66 222.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAG19379.1 - 4.3e-34 116.9 0.0 1.2e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG19379.1 - 5e-21 74.5 0.0 2.3e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG19379.1 - 2.8e-12 46.8 0.0 1.3e-11 44.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG19379.1 - 1.2e-10 41.3 0.0 3.2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAG19379.1 - 0.00026 21.0 0.2 0.00056 20.0 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAST_1 PF06743.15 OAG19379.1 - 0.088 12.8 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Cyclin_N PF00134.23 OAG19380.1 - 7.3e-10 38.7 0.1 4.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain p450 PF00067.22 OAG19381.1 - 1.4e-49 169.1 0.0 2.4e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MutL_C PF08676.11 OAG19383.1 - 4.5e-22 78.4 0.0 9.8e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAG19383.1 - 7e-20 70.9 0.4 6.3e-19 67.8 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG19383.1 - 1.2e-10 41.3 0.0 3.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG19383.1 - 3.7e-07 30.6 0.1 1.4e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NOA36 PF06524.12 OAG19383.1 - 6.1 6.1 11.4 0.25 10.6 0.8 2.2 2 0 0 2 2 2 0 NOA36 protein SieB PF14163.6 OAG19384.1 - 0.0079 15.7 0.4 0.01 15.3 0.4 1.1 1 0 0 1 1 1 1 Super-infection exclusion protein B DUF3827 PF12877.7 OAG19384.1 - 0.035 12.5 0.1 0.045 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pirin PF02678.16 OAG19385.1 - 1.4e-27 95.8 0.3 2.6e-27 94.9 0.3 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 OAG19385.1 - 1.8e-05 24.8 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 OAG19385.1 - 0.001 18.7 0.4 0.055 13.2 0.1 2.8 3 0 0 3 3 3 1 Cupin domain Methyltransf_32 PF13679.6 OAG19386.1 - 0.22 11.5 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GLTP PF08718.11 OAG19387.1 - 2.7e-47 160.8 0.0 4.4e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Iso_dh PF00180.20 OAG19388.1 - 8.5e-90 301.4 0.0 1e-89 301.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S24 PF00717.23 OAG19389.1 - 2.1e-06 27.6 0.6 1.5e-05 24.8 0.4 2.5 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 OAG19389.1 - 2.4e-05 24.1 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Iso_dh PF00180.20 OAG19390.1 - 2.6e-100 336.0 0.0 3.2e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 OAG19390.1 - 0.024 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 OAG19390.1 - 0.083 13.0 0.0 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2681 PF10883.8 OAG19392.1 - 0.018 15.4 2.2 0.026 14.9 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DivIC PF04977.15 OAG19392.1 - 0.027 14.2 1.5 0.038 13.8 1.5 1.1 1 0 0 1 1 1 0 Septum formation initiator TMEM208_SND2 PF05620.11 OAG19392.1 - 0.084 12.6 0.5 0.099 12.4 0.5 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Podoplanin PF05808.11 OAG19393.1 - 0.025 14.7 0.3 0.035 14.2 0.3 1.2 1 0 0 1 1 1 0 Podoplanin Aldo_ket_red PF00248.21 OAG19397.1 - 4e-61 206.8 0.0 4.6e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_7 PF13508.7 OAG19398.1 - 0.0026 18.2 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG19398.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG19398.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arc_C PF18162.1 OAG19400.1 - 0.042 13.7 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Arc C-lobe DUF4051 PF13260.6 OAG19400.1 - 0.057 13.1 0.2 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) BTB PF00651.31 OAG19401.1 - 2.9e-06 27.5 0.0 5.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.23 OAG19402.1 - 4.8e-19 69.2 0.0 2.2e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG19402.1 - 5.2e-05 22.9 0.0 0.00017 21.2 0.0 1.9 2 1 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG19402.1 - 0.043 12.7 0.1 0.43 9.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) HlyIII PF03006.20 OAG19403.1 - 3.9e-54 183.7 17.2 4.6e-54 183.5 17.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 OAG19403.1 - 0.0047 17.0 1.8 0.0047 17.0 1.8 2.6 2 1 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF962 PF06127.11 OAG19403.1 - 0.028 14.5 1.7 0.38 10.9 1.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF308 PF03729.13 OAG19403.1 - 0.099 13.0 17.5 0.097 13.0 2.9 4.0 5 0 0 5 5 5 0 Short repeat of unknown function (DUF308) TssN PF17555.2 OAG19403.1 - 5.5 6.3 8.5 4.9 6.5 5.6 1.9 1 1 0 2 2 2 0 Type VI secretion system, TssN PKD_channel PF08016.12 OAG19404.1 - 9e-08 31.2 21.8 5.2e-07 28.7 21.8 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OAG19404.1 - 1.3e-06 27.8 25.9 5.3e-06 25.8 25.9 1.9 1 1 0 1 1 1 1 Ion transport protein DHHC PF01529.20 OAG19404.1 - 5 7.2 11.4 1.5 8.9 2.1 2.6 1 1 2 3 3 3 0 DHHC palmitoyltransferase EIF_2_alpha PF07541.12 OAG19405.1 - 9.4e-37 125.6 0.0 1.7e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAG19405.1 - 1e-13 51.4 0.9 2e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_lid_4 PF17864.1 OAG19406.1 - 0.021 14.6 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain DUF2889 PF11136.8 OAG19406.1 - 0.15 12.4 0.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) PH_4 PF15404.6 OAG19407.1 - 3.7e-62 209.4 0.0 1.1e-61 207.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 OAG19407.1 - 1.5e-22 79.0 1.2 4.4e-22 77.5 1.2 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 OAG19407.1 - 2.7e-06 27.8 0.0 0.77 10.3 0.0 5.2 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 OAG19407.1 - 0.00075 19.8 0.1 0.064 13.5 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 OAG19407.1 - 0.086 13.3 1.8 13 6.3 0.1 3.8 3 0 0 3 3 3 0 Pleckstrin homology domain DUF3663 PF12404.8 OAG19407.1 - 0.12 12.4 0.4 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Peptidase Form-deh_trans PF09163.11 OAG19408.1 - 0.27 11.0 0.8 0.58 10.0 0.8 1.6 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Haem_degrading PF03928.14 OAG19410.1 - 1.4e-29 102.5 0.3 1.6e-29 102.3 0.3 1.0 1 0 0 1 1 1 1 Haem-degrading Glyco_hydro_45 PF02015.16 OAG19411.1 - 1.2e-64 218.1 14.7 1.6e-64 217.7 14.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 OAG19411.1 - 6.8e-13 48.3 16.1 5.7e-08 32.6 8.4 3.8 4 0 0 4 4 4 2 Fungal cellulose binding domain ATG_C PF09333.11 OAG19413.1 - 4.7e-05 23.7 0.0 0.00026 21.3 0.0 2.2 1 1 1 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OAG19413.1 - 0.074 12.8 0.3 0.85 9.4 0.1 2.5 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Cullin PF00888.22 OAG19416.1 - 4.6e-190 633.3 16.4 7e-190 632.7 16.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG19416.1 - 4.4e-26 90.7 6.0 4.4e-26 90.7 6.0 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 OAG19416.1 - 0.11 13.1 3.6 0.21 12.1 0.4 3.2 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal TPD PF14811.6 OAG19416.1 - 3.7 7.4 7.1 9 6.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function TPD sequence-motif Cupin_2 PF07883.11 OAG19417.1 - 2.3e-08 33.6 0.4 2.3e-08 33.6 0.4 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAG19417.1 - 3.9e-07 29.8 1.2 4.5e-07 29.6 0.2 1.5 2 0 0 2 2 2 1 Cupin Cupin_6 PF12852.7 OAG19417.1 - 0.0027 17.5 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG19417.1 - 0.0061 16.5 0.2 0.016 15.1 0.0 1.7 1 1 1 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG19417.1 - 0.019 14.6 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 OAG19417.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Mit_KHE1 PF10173.9 OAG19418.1 - 1.4e-60 204.6 1.1 1.4e-60 204.6 1.1 2.2 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related LRRC37AB_C PF14914.6 OAG19418.1 - 0.9 9.4 4.3 4.6 7.1 1.6 2.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain MARVEL PF01284.23 OAG19419.1 - 4.6e-05 23.5 3.5 6.9e-05 22.9 3.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain NST1 PF13945.6 OAG19419.1 - 2.6 8.1 8.9 2.2 8.4 0.1 2.5 2 1 0 2 2 2 0 Salt tolerance down-regulator TipE PF16972.5 OAG19419.1 - 9.8 5.2 9.1 14 4.7 9.1 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE adh_short_C2 PF13561.6 OAG19420.1 - 3.4e-59 200.2 1.0 5.1e-59 199.7 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19420.1 - 9.2e-50 168.8 1.2 1.9e-49 167.8 1.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG19420.1 - 2.3e-06 27.6 1.0 5e-06 26.5 1.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19420.1 - 0.02 14.3 0.2 0.069 12.6 0.0 1.9 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 OAG19420.1 - 0.056 14.0 1.0 3.4 8.3 0.1 3.2 2 1 1 3 3 3 0 Helix-hairpin-helix domain TatD_DNase PF01026.21 OAG19421.1 - 5.2e-30 104.7 0.0 8.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Avl9 PF09794.9 OAG19423.1 - 6.9e-141 469.3 0.0 8.9e-141 469.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 OAG19423.1 - 2.9e-08 33.7 0.1 0.00012 22.1 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 OAG19423.1 - 2.5e-06 27.3 3.6 0.00087 19.0 0.2 3.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 OAG19423.1 - 0.021 14.8 0.9 0.11 12.5 0.2 2.3 2 1 1 3 3 3 0 DENN (AEX-3) domain Pkinase PF00069.25 OAG19424.1 - 3e-68 230.0 0.0 4e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19424.1 - 6.7e-32 110.8 0.0 9.3e-32 110.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG19424.1 - 9.6e-06 24.8 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG19424.1 - 7.7e-05 22.1 0.1 0.00027 20.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG19424.1 - 0.00056 19.9 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG19424.1 - 0.0043 16.4 0.0 0.039 13.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OAG19424.1 - 0.0092 15.6 0.1 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAG19424.1 - 0.015 14.9 0.2 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family G-alpha PF00503.20 OAG19426.1 - 6.9e-115 384.0 0.0 8.1e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG19426.1 - 1.5e-15 57.1 1.5 7.9e-11 41.7 0.2 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG19426.1 - 2.8e-05 23.6 0.2 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG19426.1 - 0.0022 18.2 0.2 0.58 10.4 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OAG19426.1 - 0.086 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 OAG19426.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 OAG19426.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pribosyltran_N PF13793.6 OAG19429.1 - 5.2e-43 145.7 0.0 8.2e-42 141.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG19429.1 - 2e-33 116.0 0.2 7.4e-27 94.6 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG19429.1 - 2.2e-06 27.3 0.1 0.00065 19.2 0.1 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Peptidase_C2 PF00648.21 OAG19431.1 - 4.9e-64 216.2 0.6 3.9e-62 209.9 0.3 3.0 2 1 0 2 2 2 1 Calpain family cysteine protease tRNA-synt_1e PF01406.19 OAG19431.1 - 4.9 6.4 10.6 0.2 10.9 3.7 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SMP_LBD PF17047.5 OAG19432.1 - 2.6e-25 88.9 0.1 3.9e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 OAG19432.1 - 1.2e-17 64.1 0.0 2.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain COesterase PF00135.28 OAG19433.1 - 2.5e-88 297.2 0.0 1e-76 258.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG19433.1 - 3.8e-10 40.0 0.0 9.6e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1098 PF06497.11 OAG19433.1 - 0.068 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Epimerase PF01370.21 OAG19434.1 - 2.1e-23 83.0 0.0 2.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG19434.1 - 2e-12 47.2 0.0 1.1e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG19434.1 - 5.4e-11 42.0 0.0 7.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG19434.1 - 1.2e-09 37.7 0.0 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG19434.1 - 7.5e-07 28.6 0.0 0.0097 15.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 OAG19434.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 OAG19434.1 - 0.00031 20.7 0.0 0.0023 17.9 0.0 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG19434.1 - 0.00076 19.4 0.0 0.0014 18.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG19434.1 - 0.0091 15.2 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Lipase_GDSL_2 PF13472.6 OAG19434.1 - 0.011 16.1 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.25 OAG19434.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Peroxidase_2 PF01328.17 OAG19435.1 - 3.8e-44 151.5 0.0 5.1e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Chitin_bind_1 PF00187.19 OAG19436.1 - 2e-16 60.2 70.8 1.5e-07 31.7 15.1 3.8 4 0 0 4 4 4 3 Chitin recognition protein SNF2_N PF00176.23 OAG19437.1 - 4.8e-63 213.0 0.0 1.7e-62 211.2 0.0 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG19437.1 - 3e-20 72.6 0.1 5.4e-19 68.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG19437.1 - 9.5e-10 38.7 0.3 1e-08 35.3 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG19437.1 - 1e-09 38.0 0.0 2.3e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Acetyltransf_1 PF00583.25 OAG19438.1 - 3.3e-09 37.0 0.0 4.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG19438.1 - 1.4e-08 34.7 0.0 3.9e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG19438.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG19438.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG19438.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HAMP_N3 PF18575.1 OAG19438.1 - 0.067 12.8 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 HAMP N-terminal domain 3 Acetyltransf_1 PF00583.25 OAG19439.1 - 4.7e-09 36.5 0.0 1.7e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG19439.1 - 9.7e-07 28.8 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG19439.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG19439.1 - 0.0002 21.5 0.0 0.056 13.5 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG19439.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_32C PF08244.12 OAG19440.1 - 7.6e-25 87.8 1.1 1.3e-24 86.9 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 OAG19440.1 - 1.7e-15 57.4 0.0 4.9e-15 55.9 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain AA_permease_2 PF13520.6 OAG19441.1 - 5.4e-15 55.2 19.5 6.1e-15 55.0 19.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG19441.1 - 9.3e-07 27.8 16.5 1.1e-06 27.5 16.5 1.1 1 0 0 1 1 1 1 Amino acid permease DSPc PF00782.20 OAG19442.1 - 4.3e-10 39.5 0.1 1.2e-09 38.1 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAG19442.1 - 0.018 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OAG19442.1 - 0.085 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TMV_coat PF00721.21 OAG19442.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) PLA2_B PF01735.18 OAG19443.1 - 1.6e-25 89.5 0.0 2.5e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-CCHC PF00098.23 OAG19443.1 - 0.25 11.5 0.5 0.5 10.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Exo70 PF03081.15 OAG19444.1 - 2.9e-89 299.8 0.1 7.3e-89 298.4 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit AAL_decarboxy PF03306.13 OAG19444.1 - 0.02 14.2 0.2 0.61 9.4 0.1 2.4 1 1 0 2 2 2 0 Alpha-acetolactate decarboxylase NPV_P10 PF05531.12 OAG19444.1 - 0.61 10.6 4.1 10 6.6 0.1 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Septin PF00735.18 OAG19445.1 - 1.8e-120 401.5 1.3 1.8e-120 401.5 1.3 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG19445.1 - 4.1e-08 33.3 2.2 4.5e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG19445.1 - 0.00015 21.4 6.9 0.00071 19.2 0.0 3.2 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 OAG19445.1 - 0.00043 19.7 0.0 0.00043 19.7 0.0 2.7 2 1 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 OAG19445.1 - 0.00064 20.2 5.2 0.019 15.4 0.0 2.7 2 1 1 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 OAG19445.1 - 0.001 19.0 0.6 0.001 19.0 0.6 3.7 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAG19445.1 - 0.0017 18.8 0.2 0.0052 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 OAG19445.1 - 0.0026 18.0 0.0 0.0084 16.3 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG19445.1 - 0.0028 17.3 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 OAG19445.1 - 0.0051 17.1 0.7 0.037 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG19445.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG19445.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG19445.1 - 0.015 15.0 0.0 0.049 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG19445.1 - 0.025 15.0 1.8 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 OAG19445.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 OAG19445.1 - 0.32 11.0 13.1 0.3 11.1 0.6 4.0 3 2 0 3 3 2 0 Dynamin family Exonuc_VII_L PF02601.15 OAG19445.1 - 0.85 9.1 10.3 1.7 8.2 10.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4085 PF13315.6 OAG19445.1 - 0.9 9.1 12.3 0.1 12.2 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) DUF3987 PF13148.6 OAG19445.1 - 1.8 7.5 0.0 1.8 7.5 0.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 OAG19445.1 - 2.3 8.2 7.4 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Atg14 PF10186.9 OAG19445.1 - 8.7 5.3 13.7 14 4.7 13.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0121 PF03661.13 OAG19446.1 - 5.1e-30 104.6 3.4 6.6e-30 104.3 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF212 PF02681.14 OAG19446.1 - 0.076 13.1 0.1 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF1582 PF07621.11 OAG19447.1 - 0.047 13.6 0.2 0.086 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1582) Phosphorylase PF00343.20 OAG19449.1 - 0 1070.0 0.0 0 1069.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Yip1 PF04893.17 OAG19450.1 - 2.3e-11 43.7 14.9 2.3e-11 43.7 14.9 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 OAG19450.1 - 0.019 14.5 4.2 0.037 13.5 4.1 1.4 1 1 0 1 1 1 0 YIF1 ApbA PF02558.16 OAG19452.1 - 1.2e-31 109.5 0.0 1.7e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG19452.1 - 1.7e-26 92.9 0.0 2e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 OAG19452.1 - 0.11 12.8 0.6 0.55 10.5 0.2 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAG19452.1 - 0.18 11.0 0.2 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAG19452.1 - 0.19 11.0 0.5 0.28 10.5 0.5 1.2 1 0 0 1 1 1 0 ThiF family ThiD2 PF17792.1 OAG19453.1 - 4.5 7.8 8.6 0.52 10.8 1.6 2.3 2 0 0 2 2 2 0 ThiD2 family U79_P34 PF03064.16 OAG19454.1 - 7.2 5.9 9.8 3 7.1 7.2 1.6 1 1 1 2 2 2 0 HSV U79 / HCMV P34 Peptidase_S66 PF02016.15 OAG19457.1 - 0.2 11.7 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain V-set_CD47 PF08204.11 OAG19458.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain DevR PF01905.16 OAG19458.1 - 0.092 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Peroxidase_2 PF01328.17 OAG19463.1 - 8.7e-34 117.7 0.0 1.2e-33 117.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Methyltransf_11 PF08241.12 OAG19464.1 - 1.2e-15 57.9 0.1 3.6e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG19464.1 - 6.3e-15 55.7 0.2 1.8e-14 54.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG19464.1 - 4.2e-13 49.4 0.0 9e-13 48.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG19464.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG19464.1 - 2.6e-07 31.3 0.0 4.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG19464.1 - 9.9e-07 28.7 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG19464.1 - 5.6e-06 26.0 0.1 8.5e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG19464.1 - 0.00021 20.9 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG19464.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_18 PF12847.7 OAG19464.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAG19464.1 - 0.047 13.0 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAG19464.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Phosphonate-bd PF12974.7 OAG19467.1 - 0.00056 19.6 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4135 PF13575.6 OAG19467.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Extensin_2 PF04554.13 OAG19467.1 - 8.7 6.5 12.8 1.1 9.4 3.1 2.4 2 0 0 2 2 2 0 Extensin-like region SnoaL_4 PF13577.6 OAG19468.1 - 2.8e-06 27.5 0.0 4.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Thiolase_N PF00108.23 OAG19469.1 - 1.7e-66 224.2 0.7 2.5e-66 223.7 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG19469.1 - 6.2e-42 142.1 0.2 6.2e-42 142.1 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain SKG6 PF08693.10 OAG19470.1 - 0.00011 21.5 0.6 0.00024 20.4 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG19470.1 - 0.032 14.3 0.3 0.073 13.2 0.3 1.6 1 1 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 OAG19470.1 - 0.048 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF202 PF02656.15 OAG19470.1 - 0.068 13.6 0.1 0.45 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4690 PF15756.5 OAG19470.1 - 0.084 13.5 4.6 0.15 12.7 0.1 2.9 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF2681 PF10883.8 OAG19470.1 - 0.22 12.0 0.0 0.36 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MtrF PF09472.10 OAG19470.1 - 5.3 6.5 6.0 9.4 5.7 6.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sorting_nexin PF03700.13 OAG19477.1 - 0.0076 16.8 0.1 0.011 16.3 0.1 1.3 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain NmrA PF05368.13 OAG19478.1 - 7.8e-19 68.2 0.0 9.8e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG19478.1 - 4.4e-10 39.7 0.0 1.4e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Carn_acyltransf PF00755.20 OAG19479.1 - 1.1e-205 684.7 0.1 1.3e-205 684.5 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FixQ PF05545.11 OAG19480.1 - 0.16 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ldh_1_C PF02866.18 OAG19481.1 - 4.7e-48 163.3 0.0 1.3e-47 161.8 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG19481.1 - 6.2e-43 146.3 0.1 9.5e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG19481.1 - 0.0035 16.4 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 OAG19481.1 - 0.056 12.8 0.1 0.71 9.2 0.1 2.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DNA_ligase_A_C PF04679.15 OAG19483.1 - 0.15 12.7 0.2 29 5.3 0.0 2.4 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region DUF4507 PF14964.6 OAG19484.1 - 0.072 12.0 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) MFS_1 PF07690.16 OAG19485.1 - 7e-35 120.6 28.6 7e-35 120.6 28.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.11 OAG19485.1 - 0.067 12.9 0.8 0.26 10.9 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Exo_endo_phos PF03372.23 OAG19486.1 - 2.8e-06 27.0 0.0 6.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Solute_trans_a PF03619.16 OAG19490.1 - 3.5e-98 328.4 10.3 4.2e-98 328.1 10.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TSC22 PF01166.18 OAG19491.1 - 0.041 14.2 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Ferric_reduct PF01794.19 OAG19492.1 - 3.8e-23 81.9 10.4 3.8e-23 81.9 10.4 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG19492.1 - 9.2e-15 55.1 0.9 4.8e-12 46.3 0.0 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG19492.1 - 2.7e-10 40.3 0.1 0.00011 22.3 0.0 2.9 2 1 1 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 OAG19492.1 - 0.0022 18.6 0.0 0.0083 16.8 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Cortexin PF11057.8 OAG19492.1 - 0.3 11.0 0.1 0.3 11.0 0.1 2.6 3 0 0 3 3 3 0 Cortexin of kidney Methyltransf_10 PF05971.12 OAG19494.1 - 2.2e-54 184.8 0.0 3.3e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OAG19494.1 - 3e-06 26.9 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAG19494.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAG19494.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG19494.1 - 0.039 14.7 0.0 0.14 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 OAG19494.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 OAG19495.1 - 4e-33 114.0 0.0 6.5e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAG19495.1 - 3.3e-30 103.5 0.1 4.9e-30 103.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAG19495.1 - 1e-14 53.6 0.2 1e-14 53.6 0.2 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 OAG19495.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG19495.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAG19495.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LSDAT_prok PF18171.1 OAG19495.1 - 0.05 12.8 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote ThiF PF00899.21 OAG19495.1 - 0.079 12.3 1.0 0.55 9.6 0.0 2.1 1 1 1 2 2 2 0 ThiF family FYVE PF01363.21 OAG19496.1 - 5.2e-20 71.4 25.6 1.3e-15 57.3 9.1 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 OAG19496.1 - 2.4e-19 68.8 1.5 6.3e-19 67.4 1.5 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 OAG19496.1 - 0.0031 17.6 1.0 0.0031 17.6 1.0 4.1 5 1 1 6 6 4 1 AN1-like Zinc finger YqaH PF17448.2 OAG19496.1 - 0.0094 16.2 0.2 0.027 14.8 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized YqaH-like zf-Di19 PF05605.12 OAG19496.1 - 0.036 14.4 0.0 0.036 14.4 0.0 3.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding C6_DPF PF10170.9 OAG19496.1 - 0.053 13.9 0.9 0.053 13.9 0.9 2.6 2 1 0 2 2 2 0 Cysteine-rich domain Seryl_tRNA_N PF02403.22 OAG19496.1 - 0.092 13.0 1.3 0.36 11.1 1.3 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 OAG19496.1 - 0.19 12.0 6.8 9.5 6.6 2.8 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain Pap_E4 PF02711.14 OAG19496.1 - 0.24 12.4 4.1 0.69 10.9 0.7 2.9 2 0 0 2 2 2 0 E4 protein zf-C2HC5 PF06221.13 OAG19496.1 - 0.25 11.4 17.4 1.7 8.7 0.1 4.7 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type DUF2225 PF09986.9 OAG19496.1 - 0.27 10.9 5.7 0.74 9.5 3.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) UBZ_FAAP20 PF15750.5 OAG19496.1 - 0.55 10.2 3.5 3.2 7.8 0.4 3.3 3 0 0 3 3 2 0 Ubiquitin-binding zinc-finger zf-C2H2_4 PF13894.6 OAG19496.1 - 0.73 10.8 30.1 1.3 10.1 0.0 5.8 5 1 1 6 6 5 0 C2H2-type zinc finger zf-met PF12874.7 OAG19496.1 - 1.4 9.4 8.4 7.4 7.1 0.7 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FUSC PF04632.12 OAG19496.1 - 3 6.2 4.0 3.3 6.1 0.8 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family TolA_bind_tri PF16331.5 OAG19496.1 - 3.5 7.8 5.9 0.96 9.6 0.1 2.9 3 0 0 3 3 2 0 TolA binding protein trimerisation TRAF6_Z2 PF18048.1 OAG19496.1 - 4.9 7.3 7.8 20 5.4 0.8 3.0 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Bestrophin PF01062.21 OAG19497.1 - 4.2e-31 108.4 0.0 5.4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 OAG19497.1 - 0.061 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE tRNA-synt_1c PF00749.21 OAG19500.1 - 1.1e-95 320.2 0.0 1.5e-93 313.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG19500.1 - 3.1e-32 111.8 0.1 8.7e-32 110.4 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain E1-E2_ATPase PF00122.20 OAG19502.1 - 2.1e-18 66.5 0.0 5.1e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG19502.1 - 1.1e-17 65.0 1.6 1.5e-11 45.0 2.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 OAG19502.1 - 1.3e-09 37.4 2.1 2.9e-09 36.3 1.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cation_ATPase PF13246.6 OAG19502.1 - 0.0013 18.8 0.1 0.047 13.8 0.1 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG19502.1 - 0.0064 16.3 0.0 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4059 PF13268.6 OAG19502.1 - 0.9 10.0 4.3 21 5.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) HAD_2 PF13419.6 OAG19505.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG19505.1 - 0.0097 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAG19505.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 OAG19506.1 - 1.1e-69 234.8 0.0 2.2e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG19506.1 - 2.7e-13 50.2 0.0 6.6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 OAG19506.1 - 0.00069 19.5 0.8 0.0013 18.6 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 OAG19506.1 - 0.00099 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG19506.1 - 0.018 15.0 0.0 0.053 13.5 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HIRAN PF08797.11 OAG19506.1 - 0.028 14.4 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 HIRAN domain WW PF00397.26 OAG19506.1 - 0.12 12.4 3.9 0.61 10.2 0.1 2.7 2 0 0 2 2 2 0 WW domain PI3_PI4_kinase PF00454.27 OAG19507.1 - 2.7e-41 142.0 0.0 4.2e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FANCI_HD2 PF14680.6 OAG19507.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 DASH_Ask1 PF08655.10 OAG19508.1 - 1.9e-30 104.5 0.1 2.8e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 adh_short PF00106.25 OAG19509.1 - 2.4e-52 177.2 2.1 3e-52 177.0 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19509.1 - 2.8e-52 177.6 2.9 4.7e-52 176.9 2.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19509.1 - 1.8e-11 44.2 0.5 3.7e-11 43.2 0.5 1.5 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 OAG19509.1 - 0.00024 21.6 0.7 0.044 14.4 0.1 3.2 2 1 1 3 3 3 1 Helix-hairpin-helix domain Epimerase PF01370.21 OAG19509.1 - 0.0015 18.1 0.4 0.0033 16.9 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNA_pol_A_CTD PF03118.15 OAG19509.1 - 0.14 11.9 0.1 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Darcynin PF17074.5 OAG19510.1 - 0.014 15.6 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Darcynin, domain of unknown function T3SSipB PF16535.5 OAG19513.1 - 0.001 19.5 0.9 0.0013 19.2 0.9 1.1 1 0 0 1 1 1 1 Type III cell invasion protein SipB Alanine_zipper PF11839.8 OAG19513.1 - 0.0075 16.6 0.7 0.0094 16.3 0.7 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Spc7 PF08317.11 OAG19513.1 - 0.0092 14.9 4.4 0.01 14.7 4.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.12 OAG19513.1 - 0.012 15.6 0.4 0.015 15.3 0.4 1.1 1 0 0 1 1 1 0 Laminin Domain II SH3BP5 PF05276.14 OAG19513.1 - 0.014 15.2 5.2 0.017 14.9 5.2 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) UCR_hinge PF02320.16 OAG19513.1 - 0.019 15.2 3.4 0.027 14.7 3.4 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Fib_alpha PF08702.10 OAG19513.1 - 0.023 14.9 1.1 0.029 14.6 1.1 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4398 PF14346.6 OAG19513.1 - 0.031 14.9 5.1 0.043 14.4 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF573 PF04504.14 OAG19513.1 - 0.037 14.7 1.5 0.049 14.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF4446 PF14584.6 OAG19513.1 - 0.07 13.1 2.0 0.081 12.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Exonuc_VII_S PF02609.16 OAG19513.1 - 0.084 12.9 7.2 0.12 12.5 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII small subunit nsp8 PF08717.10 OAG19513.1 - 0.11 12.3 3.3 0.14 12.0 3.3 1.1 1 0 0 1 1 1 0 nsp8 replicase DUF515 PF04415.12 OAG19513.1 - 0.13 10.6 3.6 0.15 10.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4315 PF14193.6 OAG19513.1 - 0.25 11.4 10.9 0.37 10.8 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) PTS_IIA PF02255.16 OAG19513.1 - 1.2 9.2 6.3 11 6.1 6.3 2.0 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_2 PF07719.17 OAG19513.1 - 1.8 8.9 7.0 1.6 9.1 3.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 OAG19514.1 - 5.4e-124 414.2 2.9 6.6e-124 413.9 2.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG19514.1 - 4.4e-10 39.2 0.0 1.5e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG19514.1 - 0.025 14.8 0.0 0.078 13.2 0.0 1.8 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain DUF3592 PF12158.8 OAG19516.1 - 0.057 13.5 0.0 0.089 12.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) REF PF05755.12 OAG19517.1 - 0.066 13.0 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) SKG6 PF08693.10 OAG19519.1 - 2.8e-05 23.4 0.2 4.3e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain OPA3 PF07047.12 OAG19519.1 - 0.0077 16.0 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Pan_kinase PF03309.14 OAG19519.1 - 0.086 12.7 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Type III pantothenate kinase DUF2207 PF09972.9 OAG19519.1 - 0.24 10.1 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 OAG19519.1 - 0.24 10.2 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4194 PF13835.6 OAG19520.1 - 0.059 13.1 0.2 0.13 12.0 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4194) Spo7 PF03907.13 OAG19521.1 - 3e-85 285.2 0.0 4.6e-85 284.6 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 OAG19522.1 - 1.3e-25 90.6 0.0 2.3e-25 89.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG19522.1 - 4.2e-16 58.9 0.0 1.9e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG19522.1 - 4.5e-15 56.9 0.1 5.3e-14 53.4 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 OAG19522.1 - 6.9e-06 25.6 0.0 1.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 OAG19522.1 - 0.00018 21.2 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 OAG19522.1 - 0.0036 17.4 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.7 OAG19522.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 OAG19522.1 - 0.022 14.3 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 OAG19522.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 OAG19522.1 - 0.11 12.4 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG19522.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein TPPK_C PF12555.8 OAG19523.1 - 0.55 10.3 2.1 0.94 9.6 2.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Abhydrolase_6 PF12697.7 OAG19524.1 - 4.6e-11 43.8 1.3 7e-11 43.2 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG19524.1 - 1.1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG19524.1 - 6.1e-08 32.6 0.2 1.1e-06 28.5 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG19524.1 - 0.0043 16.9 0.1 0.007 16.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 OAG19524.1 - 0.068 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.21 OAG19524.1 - 0.11 11.9 0.0 0.58 9.6 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 OAG19526.1 - 3e-100 336.2 19.6 3.4e-100 336.1 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19526.1 - 6.5e-26 91.1 26.2 1.3e-19 70.3 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.8 OAG19526.1 - 0.12 12.6 4.5 8.4 6.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Alpha-L-AF_C PF06964.12 OAG19527.1 - 5.8e-29 101.4 0.0 9.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 OAG19527.1 - 0.022 14.7 1.2 0.058 13.3 1.2 1.7 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Sulfotransfer_4 PF17784.1 OAG19528.1 - 6e-60 202.7 0.1 7.4e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG19528.1 - 0.0059 17.0 0.3 0.63 10.4 0.3 2.5 1 1 0 1 1 1 1 Sulfotransferase family AAA_18 PF13238.6 OAG19528.1 - 0.042 14.4 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain UBA_6 PF18039.1 OAG19528.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Fimbrial PF00419.20 OAG19528.1 - 0.25 11.6 0.0 0.37 11.1 0.0 1.1 1 0 0 1 1 1 0 Fimbrial protein SET PF00856.28 OAG19529.1 - 1.9e-13 51.2 0.4 8.8e-13 49.0 0.0 2.2 2 1 0 2 2 2 1 SET domain TPP_enzyme_N PF02776.18 OAG19530.1 - 1.3e-38 132.3 0.0 1.4e-37 128.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG19530.1 - 7.9e-20 71.2 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG19530.1 - 1.5e-14 53.9 0.0 6.2e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF1254 PF06863.12 OAG19531.1 - 6.1e-31 107.2 0.2 1.2e-30 106.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 OAG19531.1 - 7.4e-26 90.8 0.4 1.7e-25 89.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) NACHT PF05729.12 OAG19532.1 - 0.00013 21.9 0.0 0.00051 20.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG19532.1 - 0.00014 22.2 0.5 0.021 15.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain SesA PF17107.5 OAG19532.1 - 0.0019 18.4 0.1 0.0066 16.6 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PHM7_cyt PF14703.6 OAG19532.1 - 0.0057 16.9 1.0 0.032 14.5 0.4 2.3 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter NB-ARC PF00931.22 OAG19532.1 - 0.0071 15.6 0.0 0.038 13.2 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 OAG19532.1 - 0.016 15.7 0.1 0.016 15.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG19532.1 - 0.02 15.4 0.2 0.11 13.0 0.0 2.4 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 OAG19532.1 - 0.021 15.2 2.8 0.086 13.2 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 OAG19532.1 - 0.034 13.9 0.1 0.067 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OAG19532.1 - 0.037 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 OAG19532.1 - 0.085 13.4 0.0 0.6 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG19532.1 - 0.15 11.8 0.1 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank_3 PF13606.6 OAG19532.1 - 0.18 12.5 0.0 6.4 7.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF2484 PF10658.9 OAG19533.1 - 0.082 13.2 1.5 0.13 12.6 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2484) Sugar_tr PF00083.24 OAG19534.1 - 7.7e-111 371.1 24.8 8.8e-111 370.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19534.1 - 1.5e-28 99.8 50.2 8.7e-26 90.7 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhK PF14145.6 OAG19534.1 - 0.054 13.4 0.7 0.054 13.4 0.7 2.5 2 0 0 2 2 2 0 YrhK-like protein Lipocalin_5 PF13924.6 OAG19535.1 - 1.4e-23 83.3 0.1 1.5e-23 83.1 0.1 1.0 1 0 0 1 1 1 1 Lipocalin-like domain COesterase PF00135.28 OAG19536.1 - 3.5e-88 296.7 0.0 4.3e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG19536.1 - 1.5e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG19536.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 OAG19537.1 - 6.2e-22 78.0 32.5 6.2e-22 78.0 32.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 OAG19538.1 - 9.2e-12 44.4 0.0 1.1e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CDP-OH_P_transf PF01066.21 OAG19540.1 - 1.1e-10 42.2 1.2 1.1e-10 42.2 1.2 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FA_hydroxylase PF04116.13 OAG19541.1 - 7.9e-13 48.9 10.3 7.9e-13 48.9 10.3 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily dbPDZ_assoc PF16610.5 OAG19542.1 - 0.038 14.2 2.6 0.038 14.2 2.6 2.3 2 1 1 3 3 3 0 Unstructured region between two PDZ domains on Dlg5 HET PF06985.11 OAG19543.1 - 9.9e-35 120.0 2.4 1.8e-34 119.2 2.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hydrolase_4 PF12146.8 OAG19544.1 - 1e-50 172.3 0.1 1.2e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG19544.1 - 4.2e-15 56.9 2.4 5.8e-15 56.5 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG19544.1 - 2.1e-09 37.4 0.8 1.9e-06 27.7 0.8 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG19544.1 - 1.5e-06 27.8 0.1 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 OAG19544.1 - 0.0049 16.7 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Peptidase_S15 PF02129.18 OAG19544.1 - 0.0055 16.3 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 OAG19544.1 - 0.028 14.2 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG19544.1 - 0.11 12.2 0.4 0.19 11.4 0.3 1.5 1 1 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.12 OAG19544.1 - 0.14 10.8 0.1 0.34 9.5 0.1 1.6 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3636 PF12331.8 OAG19545.1 - 9.8e-46 155.3 0.4 1.7e-45 154.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 OAG19545.1 - 2e-06 26.7 3.6 0.014 14.0 0.0 3.4 2 1 1 3 3 3 3 DNA damage checkpoint protein DUF4140 PF13600.6 OAG19545.1 - 0.12 12.8 8.3 0.61 10.5 0.6 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 OAG19545.1 - 0.2 11.7 8.9 2.9 7.9 2.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FAM184 PF15665.5 OAG19545.1 - 0.23 11.2 13.6 0.41 10.4 13.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PRKG1_interact PF15898.5 OAG19545.1 - 0.24 12.3 11.4 0.55 11.2 11.4 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Fungal_TACC PF12709.7 OAG19545.1 - 0.55 10.7 8.7 1.5 9.3 1.7 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 OAG19545.1 - 4 6.2 9.7 6.6 5.5 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAG19545.1 - 5.9 6.1 14.8 10 5.4 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 OAG19545.1 - 6.2 6.7 11.6 11 5.9 11.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain CTP_transf_1 PF01148.20 OAG19546.1 - 2.1e-81 273.6 23.4 2.7e-81 273.3 23.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PPR_2 PF13041.6 OAG19547.1 - 4.3e-17 62.0 0.7 2.6e-05 24.3 0.0 8.2 6 2 3 9 9 9 5 PPR repeat family PPR PF01535.20 OAG19547.1 - 6.9e-13 47.9 4.5 0.42 11.0 0.0 8.1 10 1 1 11 11 11 4 PPR repeat PPR_3 PF13812.6 OAG19547.1 - 3.6e-11 43.0 0.0 0.00078 19.5 0.0 5.3 4 1 2 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OAG19547.1 - 1.2e-07 31.3 0.0 0.0017 17.7 0.0 3.1 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG19547.1 - 0.015 15.0 0.1 13 5.5 0.0 4.8 6 0 0 6 6 6 0 PPR repeat TPR_16 PF13432.6 OAG19547.1 - 0.034 14.8 0.0 6.9 7.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG19547.1 - 0.066 14.1 3.7 1.2 10.1 0.0 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat RTP PF02334.16 OAG19547.1 - 0.18 12.4 0.0 0.91 10.2 0.0 2.1 2 0 0 2 2 2 0 Replication terminator protein Sugar_tr PF00083.24 OAG19548.1 - 6.5e-99 331.8 18.8 7.7e-99 331.6 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19548.1 - 1.2e-23 83.6 21.7 1.2e-23 83.6 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG19548.1 - 0.0077 14.7 0.4 0.0077 14.7 0.4 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF587 PF04532.12 OAG19548.1 - 0.19 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF587) ABC2_membrane_2 PF12679.7 OAG19548.1 - 5.3 6.2 9.8 22 4.2 9.9 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein NmrA PF05368.13 OAG19550.1 - 4.2e-16 59.2 0.0 5.6e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG19550.1 - 8.9e-14 51.8 0.1 2.7e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG19550.1 - 4.1e-08 33.0 0.0 1.9e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG19550.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAG19550.1 - 0.011 14.8 0.1 0.028 13.5 0.0 1.8 2 1 0 2 2 2 0 RmlD substrate binding domain Pox_D5 PF03288.16 OAG19550.1 - 0.092 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like CTP_transf_like PF01467.26 OAG19550.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like bZIP_1 PF00170.21 OAG19551.1 - 3.1e-05 24.0 13.2 5.1e-05 23.3 13.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG19551.1 - 0.0007 20.1 9.5 0.0013 19.2 9.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG19551.1 - 0.00097 19.2 14.7 0.0016 18.5 14.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HRCT1 PF15758.5 OAG19551.1 - 2.3 9.2 8.4 0.38 11.7 0.5 2.8 2 1 1 3 3 3 0 Histidine-rich carboxyl terminus protein 1 RTA1 PF04479.13 OAG19552.1 - 4.1e-74 248.7 8.4 4.1e-74 248.7 8.4 1.5 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 OAG19553.1 - 2.8e-07 30.6 8.1 5.6e-07 29.6 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG19553.1 - 0.0031 16.4 0.5 0.0045 15.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3669 PF12417.8 OAG19555.1 - 6.6e-22 77.5 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Zinc finger protein DSPc PF00782.20 OAG19556.1 - 3.1e-09 36.7 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG19556.1 - 0.00043 19.9 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG19556.1 - 0.0054 16.9 0.0 0.019 15.1 0.0 1.8 1 1 1 2 2 2 1 Inositol hexakisphosphate PTEN_C2 PF10409.9 OAG19556.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.6 OAG19556.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 OAG19556.1 - 0.047 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AAA PF00004.29 OAG19557.1 - 2e-15 57.4 0.0 9e-15 55.3 0.0 2.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG19557.1 - 0.0082 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG19557.1 - 0.0096 16.3 2.0 0.021 15.2 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG19557.1 - 0.015 15.6 1.0 0.075 13.3 0.1 2.4 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 OAG19557.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Fungal_trans PF04082.18 OAG19558.1 - 2.7e-20 72.5 0.0 3.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19558.1 - 1.8e-07 31.1 10.6 3.9e-07 30.1 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.7 OAG19558.1 - 0.032 14.7 0.3 0.079 13.5 0.3 1.7 1 0 0 1 1 1 0 DinB superfamily Glyco_hydro_7 PF00840.20 OAG19560.1 - 6.1e-141 470.1 9.2 7.7e-141 469.7 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Myb_DNA-binding PF00249.31 OAG19561.1 - 0.011 16.0 0.2 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG19561.1 - 0.016 15.4 0.5 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_61 PF03443.14 OAG19562.1 - 3.7e-57 193.6 0.1 4.8e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PK PF00224.21 OAG19562.1 - 0.26 10.1 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Sugar_tr PF00083.24 OAG19563.1 - 3.1e-41 141.7 22.6 5.6e-40 137.6 22.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19563.1 - 9.5e-33 113.6 28.9 3.9e-27 95.1 8.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG19563.1 - 0.31 9.3 6.5 15 3.7 6.5 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sulfate_transp PF00916.20 OAG19564.1 - 9.6e-84 281.3 8.6 1.3e-83 280.9 8.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG19564.1 - 5.7e-17 61.4 0.0 1.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAG19564.1 - 5.5e-05 23.4 0.1 0.00025 21.3 0.0 2.3 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 OAG19564.1 - 2 8.9 12.7 0.58 10.6 4.5 2.6 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily AlaDh_PNT_N PF05222.15 OAG19565.1 - 2.5e-24 86.1 0.0 4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 OAG19565.1 - 0.0002 20.7 0.0 0.0005 19.4 0.0 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain C5-epim_C PF06662.13 OAG19565.1 - 0.18 11.3 0.0 15 5.0 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Amidase PF01425.21 OAG19567.1 - 6.2e-47 160.6 0.0 1.1e-45 156.5 0.0 2.4 1 1 0 1 1 1 1 Amidase TPR_12 PF13424.6 OAG19568.1 - 3.2e-06 27.3 21.2 0.00037 20.7 3.4 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG19568.1 - 0.0024 17.8 24.5 0.26 11.5 1.7 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG19568.1 - 0.0068 16.5 10.3 4.1 7.9 0.3 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG19568.1 - 0.018 14.9 20.7 0.084 12.8 1.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG19568.1 - 0.098 13.3 9.5 2.4 8.9 0.3 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG19568.1 - 0.16 12.9 0.5 0.16 12.9 0.5 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG19568.1 - 0.29 11.9 0.5 0.29 11.9 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OAG19568.1 - 0.58 10.3 5.9 3.8 7.6 0.3 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 OAG19568.1 - 0.59 10.3 14.6 1.1 9.4 0.7 4.9 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19568.1 - 1.5 8.7 16.4 1.9 8.4 0.5 5.0 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19568.1 - 2.5 8.6 13.7 0.57 10.7 1.8 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat LemA PF04011.12 OAG19568.1 - 2.7 7.8 4.6 9.5 6.1 0.2 3.1 2 2 1 3 3 3 0 LemA family NB-ARC PF00931.22 OAG19569.1 - 2.1e-16 59.9 0.0 9.5e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 OAG19569.1 - 2.4e-06 27.8 0.0 9.4e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG19569.1 - 5.2e-05 23.7 0.4 0.00076 19.9 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain TniB PF05621.11 OAG19569.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein DUF4381 PF14316.6 OAG19569.1 - 0.048 13.9 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ArsA_ATPase PF02374.15 OAG19569.1 - 0.26 10.4 1.3 0.83 8.8 0.4 2.3 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_24 PF13479.6 OAG19569.1 - 0.64 9.7 2.1 27 4.4 0.2 2.5 2 0 0 2 2 2 0 AAA domain Laminin_I PF06008.14 OAG19571.1 - 0.0049 16.6 3.0 0.0067 16.2 3.0 1.1 1 0 0 1 1 1 1 Laminin Domain I bZIP_1 PF00170.21 OAG19571.1 - 1.2 9.3 9.1 3.7 7.7 9.1 1.9 1 1 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.16 OAG19572.1 - 1.8e-21 76.5 43.7 2.7e-21 75.9 43.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG19572.1 - 3e-05 22.8 28.6 0.023 13.3 11.7 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein DUF2523 PF10734.9 OAG19572.1 - 7.2 7.3 14.1 1.1 9.9 1.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) FMN_red PF03358.15 OAG19573.1 - 1.5e-23 83.3 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase 2-Hacid_dh_C PF02826.19 OAG19573.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF89 PF01937.19 OAG19574.1 - 7.2e-135 449.5 0.1 8.4e-135 449.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CUTL PF16557.5 OAG19575.1 - 0.22 11.7 1.3 0.63 10.3 1.3 1.8 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB NAD_binding_10 PF13460.6 OAG19576.1 - 7.7e-14 52.0 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG19576.1 - 2.6e-09 37.0 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 OAG19576.1 - 0.0041 17.2 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG19576.1 - 0.028 14.7 0.1 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG19576.1 - 0.043 13.3 0.1 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG19576.1 - 0.058 13.8 0.3 0.53 10.7 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG19576.1 - 0.14 12.6 0.1 0.64 10.5 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding DapB_N PF01113.20 OAG19576.1 - 0.16 12.1 0.5 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OAG19576.1 - 0.18 11.0 1.0 0.43 9.7 0.1 1.9 2 0 0 2 2 2 0 Male sterility protein TPR_2 PF07719.17 OAG19577.1 - 9.3e-12 44.1 10.7 0.0017 18.3 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19577.1 - 7.5e-06 25.6 9.1 0.0072 16.1 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG19577.1 - 0.00051 20.4 9.1 0.099 13.3 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG19577.1 - 0.0022 17.4 1.0 0.0022 17.4 1.0 2.5 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 OAG19577.1 - 0.0023 18.6 11.8 8.2 7.5 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG19577.1 - 0.0061 16.5 0.8 29 5.0 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG19577.1 - 0.012 16.3 16.4 2.9 8.6 1.2 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG19577.1 - 0.45 11.0 3.8 39 4.9 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG19577.1 - 0.68 9.7 8.1 18 5.1 0.0 5.4 7 0 0 7 7 7 0 TPR repeat TPR_12 PF13424.6 OAG19577.1 - 1.2 9.5 16.8 7 7.0 0.3 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF924 PF06041.11 OAG19578.1 - 4.2e-44 150.8 0.8 5e-44 150.6 0.8 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Lactamase_B PF00753.27 OAG19579.1 - 7.5e-06 26.1 0.8 1.5e-05 25.1 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily adh_short_C2 PF13561.6 OAG19580.1 - 7.1e-54 182.8 0.1 8.4e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19580.1 - 4.8e-44 150.2 0.1 6.1e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG19580.1 - 2.1e-12 47.3 0.2 4.1e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19580.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG19580.1 - 0.013 14.9 0.0 0.034 13.5 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG19580.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 OAG19580.1 - 0.049 12.9 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 OAG19581.1 - 3e-33 115.2 24.4 3e-33 115.2 24.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_2 PF02230.16 OAG19582.1 - 1.3e-26 93.8 0.0 1.6e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAG19582.1 - 0.00027 21.6 0.6 0.057 14.0 0.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG19582.1 - 0.00044 19.8 0.3 0.0017 17.9 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG19582.1 - 0.002 17.8 0.7 2.7 7.6 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG19582.1 - 0.0032 16.8 0.2 0.077 12.3 0.0 2.6 2 1 1 3 3 3 1 Serine aminopeptidase, S33 DLH PF01738.18 OAG19582.1 - 0.038 13.6 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 OAG19582.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AMP-binding PF00501.28 OAG19583.1 - 1.2e-66 225.1 0.0 1.7e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 OAG19583.1 - 1.8e-40 139.0 19.9 9.5e-39 133.3 14.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG19583.1 - 4.5e-09 35.7 2.6 9.1e-09 34.7 1.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter AMP-binding_C PF13193.6 OAG19583.1 - 9.7e-05 23.3 0.0 0.00026 21.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LacY_symp PF01306.19 OAG19583.1 - 0.15 10.8 3.0 0.25 10.1 3.0 1.3 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_1_like PF12832.7 OAG19583.1 - 0.18 10.6 5.3 4.6 6.0 5.2 2.8 1 1 0 1 1 1 0 MFS_1 like family 4HBT PF03061.22 OAG19584.1 - 3.8e-07 30.4 0.0 6.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily MRP-S33 PF08293.11 OAG19585.1 - 1.2e-28 99.2 0.0 1.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 OAG19586.1 - 2.4e-13 50.6 0.4 9.3e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG19586.1 - 5.2e-11 42.8 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like GARS_A PF01071.19 OAG19587.1 - 2e-84 282.2 0.0 3.3e-84 281.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 OAG19587.1 - 1.4e-34 118.8 0.0 3e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 OAG19587.1 - 2.5e-27 94.9 0.8 6.3e-27 93.7 0.8 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 OAG19587.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG19587.1 - 7.7e-05 22.8 0.0 0.00028 21.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OAG19587.1 - 8.4e-05 22.2 0.2 0.00017 21.2 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 OAG19587.1 - 0.00078 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG19587.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 OAG19587.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OAG19587.1 - 0.055 12.7 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 OAG19587.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OAG19587.1 - 0.16 11.7 0.0 28 4.4 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon DCP1 PF06058.13 OAG19588.1 - 2.2e-29 101.7 0.0 3.5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family BURP PF03181.15 OAG19588.1 - 0.2 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 BURP domain Exo_endo_phos PF03372.23 OAG19589.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 OAG19589.1 - 0.00016 21.5 0.1 0.00036 20.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIDHydrolase PF10230.9 OAG19590.1 - 4.8e-75 252.5 0.0 5.6e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAG19590.1 - 1.6e-05 25.6 0.1 2.4e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAG19590.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 OAG19590.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OAG19590.1 - 0.0013 18.1 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG19590.1 - 0.0038 17.4 0.0 0.0059 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.15 OAG19590.1 - 0.0066 15.7 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 OAG19590.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 OAG19590.1 - 0.044 13.6 0.0 0.091 12.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) YuiB PF14068.6 OAG19590.1 - 0.045 14.3 0.1 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative membrane protein DUF1749 PF08538.10 OAG19590.1 - 0.15 11.1 0.0 0.53 9.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) DUF676 PF05057.14 OAG19590.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HET PF06985.11 OAG19591.1 - 3.8e-36 124.6 0.2 6.5e-36 123.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3978 PF13123.6 OAG19591.1 - 0.093 12.5 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) RTA1 PF04479.13 OAG19592.1 - 9.1e-70 234.5 7.4 1.3e-69 234.0 7.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 OAG19593.1 - 2.2e-17 62.9 9.2 5.8e-17 61.6 9.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PYRIN PF02758.16 OAG19593.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Prominin PF05478.11 OAG19594.1 - 0.049 11.6 1.3 0.072 11.1 1.3 1.1 1 0 0 1 1 1 0 Prominin DUF728 PF05304.12 OAG19594.1 - 0.26 11.1 2.5 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Pkinase PF00069.25 OAG19595.1 - 9.8e-68 228.4 0.4 1e-66 225.0 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19595.1 - 1.3e-53 181.9 0.8 1.7e-53 181.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAG19595.1 - 6.6e-22 77.6 0.0 1.6e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 OAG19595.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 OAG19595.1 - 9e-06 24.7 0.0 9e-06 24.7 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAG19595.1 - 6.4e-05 22.4 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 OAG19595.1 - 8.4e-05 22.9 0.0 0.00026 21.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OAG19595.1 - 0.00095 18.2 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG19595.1 - 1.1 9.1 6.5 0.62 9.9 0.2 3.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 OAG19596.1 - 1.1e-27 96.8 34.5 2.8e-23 82.3 23.3 2.6 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family S1FA PF04689.13 OAG19596.1 - 0.06 13.5 1.0 1.2 9.4 1.0 2.7 2 0 0 2 2 2 0 DNA binding protein S1FA PetM PF08041.11 OAG19596.1 - 0.53 9.9 5.8 10 5.8 0.3 3.2 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 CH PF00307.31 OAG19597.1 - 6.4e-47 158.2 0.2 3e-23 82.1 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAG19597.1 - 6.4e-29 99.9 1.6 4.3e-26 90.8 0.2 2.7 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAG19597.1 - 5.4e-10 39.0 0.2 6.3e-07 29.1 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 OAG19597.1 - 0.0071 16.2 0.4 0.22 11.5 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain CH_2 PF06294.11 OAG19597.1 - 0.0087 16.2 0.1 0.21 11.7 0.1 2.7 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF2884 PF11101.8 OAG19597.1 - 0.012 15.1 0.3 0.012 15.1 0.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2884) DHR10 PF18595.1 OAG19597.1 - 0.015 15.3 2.4 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain NADH-UOR_E PF16514.5 OAG19597.1 - 0.02 15.2 0.7 0.9 9.9 0.1 3.2 2 1 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E EF-hand_1 PF00036.32 OAG19597.1 - 0.045 13.3 0.1 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 EF hand Spectrin PF00435.21 OAG19597.1 - 0.061 13.8 5.9 6.8 7.2 0.1 3.4 3 0 0 3 3 3 0 Spectrin repeat EF-hand_8 PF13833.6 OAG19597.1 - 0.07 13.0 0.3 0.76 9.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair DUF5055 PF16478.5 OAG19597.1 - 0.08 13.2 0.6 3.1 8.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5055) Baculo_PEP_C PF04513.12 OAG19597.1 - 0.08 13.0 3.3 0.17 11.9 1.3 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SesA PF17107.5 OAG19597.1 - 0.15 12.3 0.9 0.95 9.7 0.5 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases EF-hand_7 PF13499.6 OAG19597.1 - 0.29 11.6 4.7 0.11 12.9 0.5 2.6 3 0 0 3 3 3 0 EF-hand domain pair DUF4508 PF14969.6 OAG19597.1 - 0.87 9.9 5.2 1.5 9.2 0.4 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4508) FliG_N PF14842.6 OAG19597.1 - 1.2 9.7 4.3 2.1 9.0 0.1 3.1 3 1 0 4 4 3 0 FliG N-terminal domain CK2S PF15011.6 OAG19599.1 - 0.00068 19.6 0.1 0.028 14.3 0.1 2.5 3 0 0 3 3 3 1 Casein Kinase 2 substrate Allexi_40kDa PF05549.11 OAG19599.1 - 0.0024 17.5 0.5 0.006 16.1 0.5 1.6 1 0 0 1 1 1 1 Allexivirus 40kDa protein Tom7 PF08038.12 OAG19600.1 - 1.5e-21 75.8 0.2 1.7e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.22 OAG19601.1 - 7e-33 112.3 0.0 2.1e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG19601.1 - 0.00029 20.9 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OAG19601.1 - 0.0005 19.7 0.1 0.057 13.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OAG19601.1 - 0.0036 17.0 0.2 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.8 OAG19601.1 - 0.0043 17.1 0.1 0.097 12.8 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 PHM7_cyt PF14703.6 OAG19601.1 - 0.061 13.6 0.1 7 6.8 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cas_Cas2CT1978 PF09707.10 OAG19601.1 - 0.088 12.9 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.10 OAG19602.1 - 4.2e-47 158.6 0.0 4.8e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 OAG19603.1 - 1.5e-28 99.8 0.4 2.1e-28 99.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Med3 PF11593.8 OAG19603.1 - 6.4 5.8 9.4 7.6 5.6 9.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Patatin PF01734.22 OAG19605.1 - 1.4e-09 38.4 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.16 OAG19606.1 - 1.1e-23 83.7 17.5 4e-23 81.9 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 OAG19607.1 - 2.6e-93 313.6 6.6 4.3e-93 312.9 6.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OAG19607.1 - 2.7e-06 27.5 0.0 4.7e-05 23.6 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OAG19607.1 - 0.00017 21.9 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Ribosomal_S10 PF00338.22 OAG19608.1 - 3.1e-25 88.2 0.0 7e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.20 OAG19609.1 - 5e-55 186.3 3.0 9e-55 185.5 3.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 OAG19610.1 - 5.6e-39 132.4 1.1 5.6e-39 132.4 1.1 2.3 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing CTX_RstB PF07459.11 OAG19610.1 - 0.017 15.3 0.3 0.041 14.1 0.2 1.6 2 0 0 2 2 2 0 CTX phage RstB protein CBFD_NFYB_HMF PF00808.23 OAG19611.1 - 3.3e-19 68.9 0.5 4.7e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG19611.1 - 9.8e-15 55.1 0.2 1.7e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 OAG19611.1 - 0.048 14.0 0.2 0.099 13.0 0.0 1.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Ldh_1_C PF02866.18 OAG19612.1 - 5.4e-47 159.8 0.1 1e-46 158.9 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG19612.1 - 3.3e-46 156.9 0.1 4.6e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG19612.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG19612.1 - 0.001 19.0 0.0 0.0069 16.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_hydro_4 PF02056.16 OAG19612.1 - 0.011 15.4 0.1 0.65 9.5 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 OAG19612.1 - 0.064 12.6 0.0 0.32 10.3 0.0 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAPP PF04051.16 OAG19613.1 - 3.5e-41 140.3 0.0 4.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SSF PF00474.17 OAG19614.1 - 3.3e-20 72.3 27.0 4.9e-20 71.8 27.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family LapA_dom PF06305.11 OAG19614.1 - 0.078 12.8 0.1 0.078 12.8 0.1 4.2 6 1 1 7 7 7 0 Lipopolysaccharide assembly protein A domain Alk_phosphatase PF00245.20 OAG19614.1 - 0.12 11.3 1.1 0.17 10.8 1.1 1.1 1 0 0 1 1 1 0 Alkaline phosphatase DUF1768 PF08719.11 OAG19615.1 - 2.2e-44 151.5 0.0 4.4e-44 150.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Lipase_GDSL_2 PF13472.6 OAG19616.1 - 2.6e-13 50.7 1.7 1.8e-12 48.1 1.7 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG19616.1 - 4.8e-07 30.0 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Flg_new PF09479.10 OAG19616.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) UreF PF01730.16 OAG19617.1 - 2.6e-23 83.1 3.2 4.1e-23 82.4 3.2 1.3 1 0 0 1 1 1 1 UreF Pox_A_type_inc PF04508.12 OAG19617.1 - 0.016 15.1 0.9 0.066 13.1 0.2 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FliH PF02108.16 OAG19617.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein FliH Spo12 PF05032.12 OAG19618.1 - 1.9e-15 56.5 3.8 4.7e-15 55.2 3.8 1.7 1 0 0 1 1 1 1 Spo12 family BRE1 PF08647.11 OAG19619.1 - 2.9e-23 81.8 9.7 2.9e-23 81.8 9.7 6.9 3 2 3 6 6 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 OAG19619.1 - 5.3e-09 35.8 8.5 1.2e-08 34.7 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG19619.1 - 6.3e-09 35.5 10.9 1.2e-08 34.6 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG19619.1 - 2.6e-07 30.4 6.8 5e-07 29.5 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG19619.1 - 4.3e-07 29.7 11.6 8.9e-07 28.7 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG19619.1 - 5.2e-07 29.6 6.2 1.2e-06 28.5 6.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG19619.1 - 1.6e-06 28.3 8.6 3.2e-06 27.4 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG19619.1 - 8.2e-06 25.7 11.3 1.6e-05 24.7 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 OAG19619.1 - 0.00094 19.2 5.4 0.0025 17.9 5.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) ATG16 PF08614.11 OAG19619.1 - 0.0038 17.5 14.5 0.0038 17.5 14.5 5.8 1 1 2 4 4 3 1 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 OAG19619.1 - 0.0039 17.3 7.1 0.008 16.3 7.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING APG6_N PF17675.1 OAG19619.1 - 0.0042 17.6 81.3 0.78 10.3 11.5 7.3 2 1 4 7 7 7 2 Apg6 coiled-coil region zf-rbx1 PF12678.7 OAG19619.1 - 0.0084 16.4 5.5 0.0084 16.4 5.5 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain DZR PF12773.7 OAG19619.1 - 0.013 15.5 7.3 0.033 14.2 7.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 OAG19619.1 - 0.015 15.1 3.2 0.03 14.2 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ABC_tran_CTD PF16326.5 OAG19619.1 - 0.042 14.1 0.1 0.042 14.1 0.1 8.8 4 2 4 9 9 9 0 ABC transporter C-terminal domain zf-RING_4 PF14570.6 OAG19619.1 - 0.045 13.5 7.3 0.11 12.3 7.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2 PF00096.26 OAG19619.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.6 3 0 0 3 3 1 0 Zinc finger, C2H2 type zinc-ribbons_6 PF07191.12 OAG19619.1 - 0.2 11.7 6.8 0.67 10.0 6.8 1.9 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.6 OAG19619.1 - 0.28 10.6 4.1 0.15 11.5 1.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OAG19619.1 - 0.32 11.9 0.1 0.32 11.9 0.1 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger XkdW PF09636.10 OAG19619.1 - 0.41 10.8 10.3 0.93 9.6 0.4 4.1 3 0 0 3 3 3 0 XkdW protein TSC22 PF01166.18 OAG19619.1 - 0.5 10.7 32.7 4.8 7.6 0.2 8.7 9 0 0 9 9 9 0 TSC-22/dip/bun family zf-RING_10 PF16685.5 OAG19619.1 - 1 9.5 9.4 0.97 9.6 6.1 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 FYVE PF01363.21 OAG19619.1 - 1.5 9.0 10.4 5.3 7.3 5.5 2.8 1 1 1 2 2 2 0 FYVE zinc finger Myb_DNA-bind_7 PF15963.5 OAG19620.1 - 1.3e-22 79.5 2.2 2.2e-22 78.8 1.1 2.0 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OAG19620.1 - 0.014 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HET PF06985.11 OAG19621.1 - 9.3e-27 94.2 0.0 1.5e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 OAG19622.1 - 8.1e-54 183.0 0.0 1.1e-53 182.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG19622.1 - 2.7e-28 99.3 0.0 5.6e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG19622.1 - 6.4e-05 22.7 0.1 0.0062 16.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG19622.1 - 0.0016 17.6 0.0 0.045 12.8 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG19622.1 - 0.0017 17.5 0.0 0.097 11.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG19622.1 - 0.0018 18.5 0.0 0.0051 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG19622.1 - 0.0037 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG19622.1 - 0.006 15.8 0.0 0.075 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG19622.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 OAG19622.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAG19622.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG19622.1 - 0.14 11.4 0.7 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family THOC2_N PF16134.5 OAG19623.1 - 2.6e-218 726.7 0.0 3.4e-218 726.3 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAG19623.1 - 5.2e-73 245.9 0.0 8.4e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAG19623.1 - 1.6e-24 85.8 0.1 4.3e-24 84.4 0.1 1.8 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Aminotran_1_2 PF00155.21 OAG19624.1 - 1.4e-81 274.5 0.0 1.9e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG19624.1 - 3.7e-06 25.7 0.0 5.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG19624.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG19624.1 - 0.0024 17.2 0.6 0.0069 15.7 0.6 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG19624.1 - 0.0078 15.6 0.3 0.013 14.8 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DuffyBP_N PF12377.8 OAG19624.1 - 0.069 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Duffy binding protein N terminal GSH_synth_ATP PF03917.17 OAG19626.1 - 4.7e-144 479.8 0.0 5.4e-144 479.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAG19626.1 - 1.4e-33 115.4 0.0 2.8e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF4203 PF13886.6 OAG19627.1 - 3.7e-51 173.7 26.1 4.8e-51 173.3 26.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4149 PF13664.6 OAG19627.1 - 0.74 10.2 4.4 2.1 8.7 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Erf4 PF10256.9 OAG19628.1 - 6e-39 132.7 0.0 8.5e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2303 PF10065.9 OAG19628.1 - 0.13 11.4 0.1 0.42 9.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2303) MBOAT_2 PF13813.6 OAG19629.1 - 1.3e-18 67.0 1.4 1.3e-18 67.0 1.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MMR_HSR1_Xtn PF16897.5 OAG19630.1 - 7e-36 122.5 0.7 1.5e-35 121.4 0.3 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAG19630.1 - 1.8e-20 72.7 0.8 3.2e-20 71.9 0.2 1.8 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 OAG19630.1 - 1.5e-19 70.2 0.0 3.9e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG19630.1 - 9.7e-11 41.4 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG19630.1 - 0.0055 16.8 0.1 2.3 8.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MCM PF00493.23 OAG19630.1 - 0.031 13.4 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 OAG19630.1 - 0.05 12.6 0.1 0.14 11.1 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OAG19630.1 - 0.14 12.4 0.2 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FA_hydroxylase PF04116.13 OAG19631.1 - 1.7e-23 83.4 17.2 1.7e-23 83.4 17.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 OAG19631.1 - 0.011 14.8 0.4 0.22 10.4 0.2 2.2 1 1 1 2 2 2 0 Major Facilitator Superfamily VHP PF02209.19 OAG19631.1 - 3 8.0 5.9 5.5 7.2 0.1 2.7 3 0 0 3 3 3 0 Villin headpiece domain Pro_racemase PF05544.11 OAG19632.1 - 1.5e-114 382.4 0.0 1.7e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 Proline racemase zf-C2H2 PF00096.26 OAG19633.1 - 4.2e-22 77.3 17.7 8.9e-05 22.7 0.9 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG19633.1 - 5.2e-16 58.3 21.0 7.2e-08 32.5 0.4 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG19633.1 - 8.7e-11 41.7 16.7 0.03 15.2 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAG19633.1 - 0.00013 22.2 5.5 0.11 12.6 0.2 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 OAG19633.1 - 0.00014 22.1 7.8 0.27 11.7 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OAG19633.1 - 0.0054 17.0 9.7 0.029 14.6 1.5 3.8 2 1 2 4 4 4 1 C2H2-type zinc ribbon zf-LYAR PF08790.11 OAG19633.1 - 0.015 15.2 7.0 7.2 6.6 0.5 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 OAG19633.1 - 0.015 15.9 3.8 30 5.3 0.1 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain C1_4 PF07975.12 OAG19633.1 - 0.092 13.0 1.9 0.92 9.8 0.2 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 OAG19633.1 - 0.65 10.1 13.4 0.64 10.1 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger ADK_lid PF05191.14 OAG19633.1 - 9.7 6.3 10.1 9 6.4 2.8 4.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid DUF4602 PF15375.6 OAG19634.1 - 1.1e-12 48.5 15.1 1.1e-12 48.5 15.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) His_biosynth PF00977.21 OAG19635.1 - 6.2e-35 120.7 0.0 7.5e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 OAG19635.1 - 0.081 12.2 0.1 0.62 9.4 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 OAG19635.1 - 0.19 11.1 0.1 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SNF2_N PF00176.23 OAG19636.1 - 2.4e-73 246.9 1.7 2.4e-73 246.9 1.7 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 OAG19636.1 - 2e-22 79.0 0.6 9e-22 77.0 0.6 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 OAG19636.1 - 1.5e-19 70.4 1.7 3.1e-17 62.9 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 OAG19636.1 - 6.7e-17 61.6 15.2 6.7e-17 61.6 15.2 4.0 3 1 1 4 4 4 1 HSA QLQ PF08880.11 OAG19636.1 - 1e-12 47.6 0.8 1e-12 47.6 0.8 2.3 2 0 0 2 2 2 1 QLQ SnAC PF14619.6 OAG19636.1 - 2.3e-12 47.3 0.1 2.3e-12 47.3 0.1 3.5 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 OAG19636.1 - 3.3e-10 40.2 0.0 3.3e-10 40.2 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Chalcone_2 PF16035.5 OAG19636.1 - 2.8 7.7 11.5 9.2 6.0 11.5 2.0 1 0 0 1 1 1 0 Chalcone isomerase like DUF463 PF04317.12 OAG19637.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AXE1 PF05448.12 OAG19637.1 - 0.16 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Methyltransf_31 PF13847.6 OAG19638.1 - 1.8e-21 76.5 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG19638.1 - 7.1e-18 64.8 0.0 4.8e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAG19638.1 - 1.5e-16 60.9 0.0 2.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG19638.1 - 9.1e-14 52.0 0.0 1.8e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GFA PF04828.14 OAG19638.1 - 1.3e-13 51.1 0.3 2.8e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_11 PF08241.12 OAG19638.1 - 5.8e-13 49.3 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG19638.1 - 1.4e-10 41.2 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG19638.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAG19638.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG19638.1 - 0.00071 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OAG19638.1 - 0.00091 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAG19638.1 - 0.013 16.5 0.0 0.042 14.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 OAG19638.1 - 0.016 14.9 0.0 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 OAG19638.1 - 0.05 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAG19638.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAG19638.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TadF PF16964.5 OAG19639.1 - 0.15 11.8 0.6 0.32 10.8 0.6 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Cu_amine_oxid PF01179.20 OAG19640.1 - 1.4e-165 551.2 0.1 1.7e-165 550.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG19640.1 - 0.0008 19.8 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF3176 PF11374.8 OAG19642.1 - 1.1e-14 54.5 1.7 2.8e-14 53.2 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short PF00106.25 OAG19643.1 - 4.6e-30 104.5 0.0 6.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19643.1 - 4.4e-19 69.0 0.0 6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19643.1 - 4.9e-09 36.3 0.0 7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19643.1 - 4.1e-05 23.2 0.0 8.1e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG19643.1 - 0.002 18.2 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAG19643.1 - 0.0021 17.3 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG19643.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 OAG19643.1 - 0.006 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG19643.1 - 0.0088 15.2 0.0 5.1 6.2 0.0 2.7 2 1 1 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 OAG19643.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG19643.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DmsC PF04976.12 OAG19644.1 - 0.027 13.9 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) DUF4838 PF16126.5 OAG19644.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) MMM1 PF10296.9 OAG19645.1 - 2.4e-137 457.4 0.0 3.2e-137 457.1 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DEC-1_N PF04625.13 OAG19645.1 - 0.079 12.0 1.7 0.13 11.3 1.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region WHIM1 PF15612.6 OAG19646.1 - 0.0099 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 YL1 PF05764.13 OAG19646.1 - 0.14 12.2 20.8 0.056 13.6 6.4 3.2 3 0 0 3 3 3 0 YL1 nuclear protein DUF2457 PF10446.9 OAG19646.1 - 0.15 11.2 23.7 0.056 12.6 12.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 OAG19646.1 - 1.7 6.8 12.2 0.04 12.1 5.9 1.5 2 0 0 2 2 2 0 Nop14-like family BAR PF03114.18 OAG19647.1 - 1.3e-49 169.1 9.0 1.6e-49 168.7 9.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OAG19647.1 - 8.5e-05 21.8 3.6 0.00012 21.4 3.6 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GBP_C PF02841.14 OAG19647.1 - 0.0093 15.4 6.7 0.0093 15.4 6.7 1.5 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Apo-CIII PF05778.12 OAG19647.1 - 0.0094 15.6 0.4 0.075 12.7 0.1 2.5 2 0 0 2 2 2 1 Apolipoprotein CIII (Apo-CIII) OmpH PF03938.14 OAG19647.1 - 2.4 8.5 15.2 2.6 8.4 9.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PRIMA1 PF16101.5 OAG19647.1 - 4.2 7.4 8.0 11 6.0 8.0 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fungal_trans PF04082.18 OAG19648.1 - 1.7e-09 37.1 0.5 2.8e-09 36.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19648.1 - 5.6e-09 36.0 7.8 1e-08 35.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 OAG19648.1 - 0.0011 17.5 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Sec1 PF00995.23 OAG19649.1 - 3.1e-134 449.3 0.1 3.6e-134 449.1 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Epimerase PF01370.21 OAG19650.1 - 1.4e-08 34.5 0.1 0.0032 17.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG19650.1 - 1.4e-07 31.5 0.1 2.5e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG19650.1 - 8.5e-06 26.2 0.1 2.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 OAG19650.1 - 0.0001 22.0 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAG19650.1 - 0.021 14.0 0.0 0.052 12.7 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 OAG19650.1 - 0.031 15.0 0.0 0.1 13.3 0.0 1.9 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GDP_Man_Dehyd PF16363.5 OAG19650.1 - 0.068 12.6 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1330 PF07045.11 OAG19651.1 - 0.025 14.9 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1330) COesterase PF00135.28 OAG19655.1 - 2.4e-40 138.9 0.0 2.9e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG19655.1 - 0.0021 17.9 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 OAG19656.1 - 0.00019 21.1 0.1 0.00051 19.8 0.1 1.7 1 1 0 1 1 1 1 Putative esterase UQ_con PF00179.26 OAG19657.1 - 5e-43 146.1 0.0 7e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAG19657.1 - 2.8e-05 23.8 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 OAG19657.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG19657.1 - 0.0026 18.0 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OAG19657.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF3235 PF11574.8 OAG19657.1 - 0.033 15.1 0.3 0.055 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) AAA PF00004.29 OAG19658.1 - 3e-41 140.9 0.0 5.3e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG19658.1 - 1.6e-11 43.8 0.3 3.3e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAG19658.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OAG19658.1 - 3.5e-06 27.2 0.0 7.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAG19658.1 - 4.3e-06 27.1 0.2 0.018 15.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 OAG19658.1 - 1.5e-05 24.3 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAG19658.1 - 1.8e-05 24.7 0.0 5.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG19658.1 - 0.00021 21.7 0.2 0.0015 19.0 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAG19658.1 - 0.00033 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG19658.1 - 0.003 17.8 0.0 0.0076 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG19658.1 - 0.007 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG19658.1 - 0.0074 16.4 0.0 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG19658.1 - 0.0089 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAG19658.1 - 0.018 14.8 0.2 0.04 13.7 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 OAG19658.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 OAG19658.1 - 0.02 14.1 1.0 0.039 13.2 0.0 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 OAG19658.1 - 0.031 13.6 0.1 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.22 OAG19658.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAG19658.1 - 0.053 13.4 0.2 0.63 9.9 0.1 2.3 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 OAG19658.1 - 0.053 13.0 0.5 0.51 9.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 OAG19658.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAG19658.1 - 0.064 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OAG19658.1 - 0.07 12.7 1.2 0.58 9.7 0.4 2.6 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG19658.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OAG19658.1 - 0.19 11.2 0.1 0.52 9.8 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OAG19658.1 - 0.2 12.1 0.4 0.91 10.0 0.4 2.2 1 1 0 1 1 1 0 ABC transporter Prot_ATP_OB_N PF17758.1 OAG19658.1 - 0.21 11.3 0.9 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 OAG19658.1 - 0.46 10.2 2.9 0.29 10.8 0.3 2.1 2 1 0 2 2 2 0 AAA domain Leptin PF02024.15 OAG19659.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Leptin Cyclin_C_2 PF16899.5 OAG19660.1 - 1.4e-27 96.1 0.1 3.1e-26 91.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 OAG19660.1 - 9.3e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1682 PF07946.14 OAG19660.1 - 0.018 14.3 0.6 0.029 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) XPA_C PF05181.12 OAG19663.1 - 5.8e-24 83.8 1.2 1.1e-23 82.9 1.2 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OAG19663.1 - 0.0039 17.2 0.2 0.0039 17.2 0.2 2.3 2 0 0 2 2 2 1 XPA protein N-terminal TF_Zn_Ribbon PF08271.12 OAG19663.1 - 0.35 10.4 2.4 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Pept_tRNA_hydro PF01195.19 OAG19664.1 - 3.6e-31 108.4 0.0 4.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase UPF0492 PF15744.5 OAG19664.1 - 0.081 12.1 0.8 0.1 11.8 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Cut12 PF11500.8 OAG19665.1 - 8.7e-27 93.8 14.5 8.7e-27 93.8 14.5 3.5 2 2 0 2 2 2 1 Spindle pole body formation-associated protein FapA PF03961.13 OAG19665.1 - 4.9 5.7 7.8 9.8 4.6 7.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A HGTP_anticodon2 PF12745.7 OAG19666.1 - 8.1e-78 261.5 1.2 2.1e-77 260.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 OAG19666.1 - 2.5e-70 236.9 0.0 4.5e-35 121.3 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19666.1 - 6.2e-40 137.1 0.0 1.3e-17 63.9 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 OAG19666.1 - 7e-15 55.3 0.0 3.1e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 OAG19666.1 - 7.3e-11 41.9 1.4 3.8e-10 39.5 0.0 2.5 2 1 1 3 3 3 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 OAG19666.1 - 0.0005 19.5 2.5 0.019 14.3 0.0 2.9 3 1 0 3 3 3 1 Kinase-like APH PF01636.23 OAG19666.1 - 0.001 19.1 3.8 0.045 13.7 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Hydant_A_N PF05378.13 OAG19666.1 - 0.099 12.3 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region FTA2 PF13095.6 OAG19666.1 - 0.29 10.7 1.4 5 6.7 0.0 3.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PA26 PF04636.13 OAG19666.1 - 0.62 8.9 2.5 1.3 7.9 2.5 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RE_HindVP PF09519.10 OAG19667.1 - 0.053 12.5 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease DUF3263 PF11662.8 OAG19667.1 - 0.067 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) DUF202 PF02656.15 OAG19668.1 - 2.6 8.6 6.2 2.8 8.5 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) zf-H2C2_2 PF13465.6 OAG19668.1 - 3.7 8.1 7.2 28 5.3 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.12 OAG19668.1 - 4.4 7.7 7.1 4.1 7.8 0.8 3.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Amidase PF01425.21 OAG19669.1 - 3.9e-32 111.8 0.0 7.1e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF676 PF05057.14 OAG19670.1 - 0.00066 19.2 0.0 0.00094 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG19670.1 - 0.037 14.6 0.0 0.046 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_12 PF13424.6 OAG19671.1 - 1.1e-14 54.5 13.9 4.2e-07 30.2 0.1 5.5 4 2 1 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG19671.1 - 4.6e-09 35.7 11.8 0.0013 18.7 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG19671.1 - 5.9e-07 29.2 8.0 0.024 14.8 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG19671.1 - 1.3e-06 27.8 0.0 2.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 OAG19671.1 - 6.4e-06 25.9 5.2 23 5.0 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19671.1 - 7e-06 26.5 2.1 0.0027 18.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19671.1 - 2.7e-05 23.8 10.2 0.0086 15.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG19671.1 - 0.00041 19.8 6.5 0.053 12.9 0.1 3.3 2 1 2 4 4 4 3 MalT-like TPR region SNAP PF14938.6 OAG19671.1 - 0.0064 16.0 3.2 0.0064 16.0 3.2 2.8 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 OAG19671.1 - 0.048 14.3 5.3 4.9 7.9 0.0 4.8 5 2 0 5 5 5 0 Tetratricopeptide repeat PTS_IIA PF02255.16 OAG19671.1 - 0.13 12.3 2.5 6.4 6.9 0.4 3.6 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_4 PF07721.14 OAG19671.1 - 0.19 12.5 2.3 24 5.9 0.4 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 OAG19671.1 - 0.31 10.4 5.0 2.5 7.4 0.2 3.3 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_14 PF13428.6 OAG19671.1 - 0.7 10.9 8.1 62 4.8 0.0 6.1 7 1 1 8 8 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG19671.1 - 0.89 9.8 9.1 8.3 6.7 0.4 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 OAG19671.1 - 2.4 7.8 10.8 0.52 10.0 3.1 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) CorA PF01544.18 OAG19672.1 - 1.2e-10 41.2 0.3 2.5e-10 40.1 0.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Mt_ATP-synt_B PF05405.14 OAG19672.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FliJ PF02050.16 OAG19672.1 - 0.92 9.7 3.6 0.43 10.8 1.1 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 OAG19673.1 - 1.5e-27 96.5 36.8 1.5e-27 96.5 36.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.27 OAG19674.1 - 2.9e-53 180.0 0.0 1.7e-29 103.1 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG19674.1 - 5.5e-49 167.3 33.7 8.8e-34 117.4 8.3 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG19674.1 - 5.2e-07 29.3 5.5 0.15 11.5 0.1 4.7 4 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG19674.1 - 8.2e-06 25.8 0.0 0.048 13.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG19674.1 - 0.00013 21.9 0.0 0.091 12.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OAG19674.1 - 0.00015 22.3 0.6 0.026 15.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG19674.1 - 0.00086 19.7 0.0 1.8 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAG19674.1 - 0.0015 18.6 0.8 0.21 11.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OAG19674.1 - 0.0052 16.3 0.6 2.1 7.9 0.3 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 OAG19674.1 - 0.0056 16.8 6.2 0.043 13.9 0.1 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 OAG19674.1 - 0.0073 16.6 2.3 9.1 6.6 0.4 3.3 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 OAG19674.1 - 0.011 15.6 0.2 25 4.6 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase T2SSE PF00437.20 OAG19674.1 - 0.013 14.6 0.3 0.23 10.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAG19674.1 - 0.016 15.0 0.9 4 7.2 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.23 OAG19674.1 - 0.022 14.8 1.2 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAG19674.1 - 0.029 13.9 3.8 1.4 8.4 0.2 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 OAG19674.1 - 0.051 12.8 1.4 6.5 6.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.6 OAG19674.1 - 0.066 13.4 0.1 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG19674.1 - 0.073 12.8 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAG19674.1 - 0.081 13.3 0.5 27 5.2 0.0 3.0 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 OAG19674.1 - 0.11 11.4 2.9 0.84 8.5 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OAG19674.1 - 0.18 11.5 4.6 4.1 7.1 0.2 2.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OAG19674.1 - 0.18 11.8 0.2 18 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG19674.1 - 0.23 11.9 2.2 43 4.5 0.4 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 OAG19674.1 - 0.25 11.4 2.5 17 5.5 0.3 2.7 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 OAG19674.1 - 0.37 10.4 3.4 1.1 8.8 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAG19674.1 - 1.3 8.9 2.9 3.5 7.5 0.3 2.4 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 OAG19674.1 - 8.4 6.6 6.1 33 4.7 0.2 3.3 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase NAD_binding_8 PF13450.6 OAG19675.1 - 7.4e-09 35.7 0.3 2.1e-08 34.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG19675.1 - 9.8e-07 28.5 1.0 1.4e-06 27.9 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG19675.1 - 1.5e-05 24.3 1.3 0.00012 21.3 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 OAG19675.1 - 2.3e-05 23.9 0.0 5.4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG19675.1 - 0.00048 20.6 0.4 0.001 19.6 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG19675.1 - 0.00051 18.9 0.6 0.00085 18.1 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG19675.1 - 0.00083 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG19675.1 - 0.0088 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG19675.1 - 0.0099 15.1 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG19675.1 - 0.017 14.4 0.7 0.026 13.8 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG19675.1 - 0.021 14.4 0.7 0.047 13.3 0.7 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 OAG19675.1 - 0.033 13.3 0.5 0.054 12.6 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.12 OAG19675.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FMO-like PF00743.19 OAG19675.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NDUFA12 PF05071.16 OAG19676.1 - 1.5e-29 102.7 4.5 1.8e-29 102.4 4.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 OAG19677.1 - 8.3e-15 54.8 0.0 1.1e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAG19677.1 - 1.9e-07 30.9 1.6 0.021 15.0 0.4 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif WWE PF02825.20 OAG19677.1 - 0.11 13.2 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 WWE domain Glyco_transf_22 PF03901.17 OAG19678.1 - 7.2e-61 206.7 26.6 9.3e-61 206.3 26.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.19 OAG19679.1 - 8.8e-29 99.4 0.5 1.5e-28 98.6 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAG19679.1 - 2.7e-20 72.3 0.2 6.9e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain SOR_SNZ PF01680.17 OAG19680.1 - 1e-109 365.1 5.8 1.8e-109 364.4 5.8 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAG19680.1 - 3.6e-10 39.6 5.2 1.9e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG19680.1 - 0.00059 19.0 0.9 0.2 10.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 OAG19680.1 - 0.00081 18.6 0.7 0.016 14.4 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 OAG19680.1 - 0.00099 18.3 0.1 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 OAG19680.1 - 0.0061 16.0 0.3 0.14 11.6 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 OAG19680.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TMP-TENI PF02581.17 OAG19680.1 - 0.039 13.3 0.5 1 8.6 0.1 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 OAG19680.1 - 0.081 12.3 6.2 0.18 11.2 0.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Creatinase_N_2 PF16189.5 OAG19681.1 - 1.4e-57 194.3 0.2 5.9e-55 185.8 0.1 3.0 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAG19681.1 - 5.2e-44 150.4 0.0 9.5e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 OAG19681.1 - 3.8e-22 79.3 0.0 4e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OAG19681.1 - 1e-20 73.5 0.4 2.8e-20 72.1 0.4 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DUF234 PF03008.14 OAG19681.1 - 0.11 13.0 0.1 20 5.7 0.0 3.2 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function Importin_rep PF18773.1 OAG19682.1 - 4.4e-05 23.1 0.1 9.7e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 OAG19682.1 - 0.0027 17.6 0.2 0.0091 15.9 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain RIX1 PF08167.12 OAG19682.1 - 0.053 13.3 2.5 1.9 8.2 0.1 3.4 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis UME PF08064.13 OAG19682.1 - 0.15 12.0 0.1 9.6 6.2 0.0 3.5 3 0 0 3 3 3 0 UME (NUC010) domain FUN14 PF04930.15 OAG19683.1 - 2.8e-07 30.8 1.1 4.8e-07 30.1 1.1 1.3 1 0 0 1 1 1 1 FUN14 family Phosphodiest PF01663.22 OAG19684.1 - 1.4e-13 51.2 1.4 3.7e-08 33.3 0.1 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG19684.1 - 0.00025 20.6 0.0 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 Sulfatase PigN PF04987.14 OAG19684.1 - 0.0037 16.2 1.8 0.0037 16.2 1.8 2.9 2 2 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Metalloenzyme PF01676.18 OAG19684.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily IBR PF01485.21 OAG19685.1 - 2.4e-11 43.7 42.6 2.7e-07 30.7 11.2 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain YhfH PF14149.6 OAG19685.1 - 0.07 13.1 5.1 0.34 10.9 5.1 2.3 1 0 0 1 1 1 0 YhfH-like protein zf-RING_2 PF13639.6 OAG19685.1 - 2.6 8.4 45.7 0.2 12.0 6.0 4.9 2 2 3 5 5 5 0 Ring finger domain MORN PF02493.20 OAG19686.1 - 1.5e-13 49.8 22.5 0.0037 17.1 0.3 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 OAG19686.1 - 4.5e-11 42.4 6.2 7.2e-11 41.8 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.8 OAG19686.1 - 1.7e-08 34.1 0.0 2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 OAG19686.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 OAG19686.1 - 0.00029 20.6 5.9 0.00055 19.7 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MATH PF00917.26 OAG19686.1 - 0.0057 16.8 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 MATH domain zf-RING_2 PF13639.6 OAG19686.1 - 0.014 15.7 6.8 0.029 14.7 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAG19686.1 - 0.083 12.9 6.2 0.16 11.9 6.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 OAG19687.1 - 7.3e-133 442.2 0.0 8.4e-133 442.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 OAG19687.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Myb_DNA-binding PF00249.31 OAG19688.1 - 6.7e-09 35.8 0.1 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG19688.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OAG19688.1 - 0.019 15.2 0.6 6.9 7.0 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain KcnmB2_inactiv PF09303.10 OAG19688.1 - 0.47 10.3 6.4 1.2 9.0 3.0 2.6 2 0 0 2 2 2 0 KCNMB2, ball and chain domain RANK_CRD_2 PF18278.1 OAG19689.1 - 0.02 15.0 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DUF908 PF06012.12 OAG19689.1 - 8.7 5.7 10.3 68 2.7 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) STE PF02200.16 OAG19690.1 - 3.1e-56 188.5 0.1 5e-56 187.8 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 OAG19690.1 - 1.3e-11 44.2 10.0 1.7e-06 28.1 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG19690.1 - 2.7e-09 37.0 2.5 2.7e-09 37.0 2.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG19690.1 - 8e-08 32.5 8.1 0.00075 20.1 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG19690.1 - 5.6e-05 23.0 3.3 0.00031 20.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG19690.1 - 0.0007 19.8 0.1 0.024 14.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG19690.1 - 0.0075 16.5 2.8 0.014 15.7 2.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding CwsA PF10814.8 OAG19690.1 - 0.01 16.0 0.2 0.025 14.7 0.2 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA zf-met PF12874.7 OAG19690.1 - 0.036 14.5 0.9 0.17 12.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 OAG19690.1 - 0.051 14.3 0.1 0.16 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNF220 PF15926.5 OAG19690.1 - 0.08 12.6 0.3 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Zn-C2H2_12 PF18112.1 OAG19690.1 - 3.4 8.2 7.0 2.4 8.7 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 OAG19690.1 - 6.7 6.6 5.7 28 4.6 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CDP-OH_P_transf PF01066.21 OAG19691.1 - 6.1e-15 55.7 0.4 6.1e-15 55.7 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1989 PF09347.10 OAG19692.1 - 1.3e-40 138.7 0.0 1.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Homeobox_KN PF05920.11 OAG19693.1 - 7.8e-12 44.9 2.7 1.8e-11 43.7 2.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG19693.1 - 1.1e-08 34.8 0.5 4.6e-07 29.6 0.2 2.6 2 0 0 2 2 2 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 OAG19693.1 - 7.6e-05 22.7 1.8 0.086 12.9 0.1 4.2 3 1 0 3 3 3 2 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAG19693.1 - 0.00072 20.2 1.4 0.00072 20.2 1.4 4.9 3 1 1 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG19693.1 - 0.026 15.0 1.2 0.026 15.0 1.2 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type Glyco_transf_10 PF00852.19 OAG19693.1 - 0.052 13.3 0.9 0.13 12.0 0.4 1.9 1 1 1 2 2 2 0 Glycosyltransferase family 10 (fucosyltransferase) C-term zf-C2H2_jaz PF12171.8 OAG19693.1 - 0.65 10.4 6.0 2.2 8.7 1.0 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ABC1 PF03109.16 OAG19694.1 - 1.2e-34 119.0 0.0 4.8e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 ABC1 family CN_hydrolase PF00795.22 OAG19695.1 - 3e-15 56.3 0.0 4.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Ribosomal_L39 PF00832.20 OAG19696.1 - 3.8e-21 74.4 9.6 4.3e-21 74.2 9.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Cation_efflux PF01545.21 OAG19697.1 - 3.9e-23 82.2 13.8 4.9e-23 81.9 13.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG19697.1 - 1.2e-07 31.7 0.1 2.3e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter BTB PF00651.31 OAG19698.1 - 0.00016 21.8 0.1 0.00056 20.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain GIDA PF01134.22 OAG19699.1 - 1.5e-155 518.1 0.0 1.9e-155 517.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OAG19699.1 - 1.7e-66 224.4 0.0 2.7e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 OAG19699.1 - 1.3e-06 27.9 0.5 3.1e-06 26.6 0.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG19699.1 - 1.8e-06 27.6 1.3 1.8e-06 27.6 1.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG19699.1 - 0.00016 20.9 2.1 0.00016 20.9 2.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG19699.1 - 0.0031 16.3 0.5 0.048 12.4 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG19699.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG19699.1 - 0.033 14.7 0.6 0.1 13.1 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG19699.1 - 0.24 10.9 2.1 13 5.2 1.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase SSB PF00436.25 OAG19700.1 - 3.1e-13 49.6 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family WD40 PF00400.32 OAG19701.1 - 7.1e-12 45.7 14.5 0.017 16.0 0.3 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG19701.1 - 0.00019 21.7 0.0 0.68 10.3 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 OAG19701.1 - 4.8 6.5 10.3 45 3.4 10.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Tom22 PF04281.13 OAG19701.1 - 7.2 6.4 6.2 18 5.1 6.2 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TENA_THI-4 PF03070.16 OAG19702.1 - 4.7e-08 33.1 0.1 8.7e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DKCLD PF08068.12 OAG19703.1 - 2.8e-32 110.6 0.2 6.5e-31 106.2 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 OAG19703.1 - 8e-23 81.5 1.2 6.1e-20 72.1 0.2 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG19703.1 - 1.6e-22 79.4 1.2 3.1e-22 78.5 1.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAG19703.1 - 6.8e-20 70.8 0.9 1.3e-19 69.9 0.9 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAG19703.1 - 0.024 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain DnaJ_C PF01556.18 OAG19704.1 - 2.7e-35 121.6 0.7 3.6e-35 121.2 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG19704.1 - 1.3e-28 98.9 2.3 2.4e-28 98.0 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain HET PF06985.11 OAG19705.1 - 5.4e-23 82.0 0.0 1e-22 81.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cation_efflux PF01545.21 OAG19708.1 - 7.9e-21 74.7 5.1 1.2e-20 74.2 5.1 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG19708.1 - 1.1e-05 25.4 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter APH PF01636.23 OAG19711.1 - 2e-16 60.7 0.1 2.9e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG19711.1 - 4e-06 26.4 0.0 1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 OAG19711.1 - 8.9e-05 21.5 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG19711.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase HET PF06985.11 OAG19712.1 - 9.3e-35 120.1 0.1 1.6e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.24 OAG19714.1 - 1e-26 93.7 25.7 1.7e-26 93.0 25.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG19714.1 - 1.3e-26 93.7 0.1 2.2e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG19714.1 - 5.9e-06 26.3 0.1 0.1 12.4 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG19714.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_25 PF13481.6 OAG19714.1 - 0.00041 20.0 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG19714.1 - 0.00054 20.4 0.1 0.001 19.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG19714.1 - 0.0034 17.7 0.0 0.0069 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG19714.1 - 0.0039 16.9 0.1 0.0083 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG19714.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 OAG19714.1 - 0.0068 16.8 0.0 0.063 13.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAG19714.1 - 0.0096 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAG19714.1 - 0.029 14.1 0.0 0.16 11.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAG19714.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 OAG19714.1 - 0.035 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SMC_N PF02463.19 OAG19714.1 - 0.053 12.9 0.0 1.2 8.5 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3785 PF12653.7 OAG19714.1 - 0.053 13.6 0.2 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3785) AAA_28 PF13521.6 OAG19714.1 - 0.054 13.7 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG19714.1 - 0.084 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG19714.1 - 0.086 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG19714.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 OAG19714.1 - 0.12 11.0 0.2 1.3 7.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAG19714.1 - 0.12 12.3 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OAG19714.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 OAG19714.1 - 0.14 11.2 23.7 0.37 9.8 13.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_7 PF12775.7 OAG19714.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 OAG19714.1 - 0.18 12.2 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.14 OAG19715.1 - 1.2e-47 161.4 5.9 1.7e-47 160.9 3.4 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OAG19715.1 - 2.1e-10 40.4 4.4 5e-10 39.1 4.4 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OAG19715.1 - 8.3e-05 21.3 1.5 0.00015 20.5 1.5 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 OAG19715.1 - 0.016 15.3 0.6 0.086 12.9 0.6 2.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.9 OAG19715.1 - 0.075 13.3 0.2 0.43 10.9 0.2 2.3 1 0 0 1 1 1 0 Uncharacterized conserved protein Vps51 PF08700.11 OAG19715.1 - 0.15 12.1 1.2 8.1 6.6 0.1 3.0 1 1 1 2 2 2 0 Vps51/Vps67 TPR_2 PF07719.17 OAG19716.1 - 2.5e-29 99.0 33.6 0.00039 20.3 0.0 14.1 16 0 0 16 16 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19716.1 - 3.2e-25 86.8 23.8 0.00037 20.2 0.1 11.9 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 OAG19716.1 - 3e-22 76.9 7.9 0.024 14.8 0.0 11.4 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG19716.1 - 3.7e-22 78.4 22.2 0.0035 17.6 1.8 9.7 8 2 1 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19716.1 - 1.9e-20 73.1 33.5 0.00054 20.4 0.0 11.5 10 3 2 12 12 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 OAG19716.1 - 1.8e-16 59.6 26.4 0.00025 21.5 0.1 13.0 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG19716.1 - 3.4e-13 49.2 39.0 0.00013 22.5 0.1 13.9 12 4 3 15 15 14 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG19716.1 - 9e-11 41.4 12.6 0.38 11.2 0.1 11.1 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG19716.1 - 1.2e-10 40.9 20.9 0.58 9.9 0.3 10.1 9 1 2 11 11 11 5 TPR repeat TPR_7 PF13176.6 OAG19716.1 - 1.2e-10 40.6 25.0 0.00078 19.3 0.0 11.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG19716.1 - 1.4e-08 35.2 38.8 0.0042 17.7 0.0 10.1 9 2 3 12 12 10 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAG19716.1 - 1.9e-05 24.4 21.5 0.52 10.3 0.3 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG19716.1 - 0.003 17.7 20.5 0.22 11.8 0.4 7.2 7 2 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OAG19716.1 - 0.0036 17.3 5.6 3.4 7.8 0.1 6.2 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Pep3_Vps18 PF05131.14 OAG19717.1 - 4.8e-48 162.8 0.0 1.4e-47 161.3 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAG19717.1 - 6.7e-11 42.2 12.0 4.8e-09 36.2 0.8 3.2 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 OAG19717.1 - 0.001 18.7 0.4 0.0023 17.5 0.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 OAG19717.1 - 0.0014 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 OAG19717.1 - 0.0022 17.8 0.9 0.0057 16.5 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG19717.1 - 0.0032 17.4 0.2 0.007 16.3 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG19717.1 - 0.01 16.1 0.8 0.028 14.8 0.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OAG19717.1 - 0.069 13.2 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF2175 PF09943.9 OAG19717.1 - 0.093 13.0 0.0 0.093 13.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.25 OAG19717.1 - 0.1 12.5 0.3 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG19717.1 - 0.13 12.6 0.4 0.33 11.3 0.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG19717.1 - 0.23 11.2 8.3 0.03 14.0 4.0 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF1664 PF07889.12 OAG19717.1 - 0.3 11.1 2.1 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FadA PF09403.10 OAG19717.1 - 1.5 9.4 4.0 0.51 10.8 0.6 2.0 2 0 0 2 2 1 0 Adhesion protein FadA zf-C3H2C3 PF17122.5 OAG19717.1 - 2.8 8.0 8.1 0.1 12.6 2.0 1.8 2 0 0 2 2 1 0 Zinc-finger BTB PF00651.31 OAG19718.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain DUF325 PF03804.13 OAG19718.1 - 0.26 11.4 0.5 3.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Viral proteins of unknown function XG_FTase PF03254.13 OAG19719.1 - 0.21 10.1 0.2 1 7.9 0.1 1.9 1 1 1 2 2 2 0 Xyloglucan fucosyltransferase adh_short PF00106.25 OAG19720.1 - 2e-26 92.6 0.1 4e-22 78.6 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19720.1 - 1.2e-14 54.5 0.0 1.7e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19720.1 - 7.7e-12 45.5 0.4 1.2e-11 44.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19720.1 - 0.0023 17.5 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG19720.1 - 0.0068 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG19720.1 - 0.0072 16.4 0.3 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 OAG19720.1 - 0.011 15.1 0.6 0.017 14.5 0.6 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase TIR-like PF10137.9 OAG19720.1 - 0.078 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NAD_binding_7 PF13241.6 OAG19720.1 - 0.085 13.3 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding RPN7 PF10602.9 OAG19720.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 STAS PF01740.21 OAG19720.1 - 0.17 11.5 0.1 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 STAS domain Asp_protease_2 PF13650.6 OAG19721.1 - 0.015 15.9 0.2 0.87 10.3 0.1 2.5 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 OAG19721.1 - 0.019 15.5 0.1 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Haem_degrading PF03928.14 OAG19722.1 - 8.4e-30 103.3 0.0 1.1e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Amidase PF01425.21 OAG19723.1 - 3.8e-70 237.1 0.0 4.2e-69 233.7 0.0 1.9 1 1 1 2 2 2 2 Amidase Pkinase PF00069.25 OAG19724.1 - 1.4e-10 41.0 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19724.1 - 0.0031 16.8 0.0 0.005 16.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG19724.1 - 0.0036 16.7 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG19724.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OAG19725.1 - 2.4e-14 53.3 0.1 2.7e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19725.1 - 0.00024 20.5 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG19725.1 - 0.0011 18.3 0.1 0.0024 17.2 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Torus PF16131.5 OAG19726.1 - 4.1e-44 149.7 0.1 4.1e-44 149.7 0.1 2.3 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 OAG19726.1 - 6.6e-07 29.1 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAG19726.1 - 0.00084 19.3 0.2 0.00084 19.3 0.2 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 OAG19726.1 - 0.002 18.0 0.3 0.0037 17.1 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAG19726.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif adh_short_C2 PF13561.6 OAG19727.1 - 6.3e-66 222.3 0.0 7.5e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19727.1 - 1.2e-53 181.5 0.0 1.5e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG19727.1 - 1.1e-10 41.7 0.3 5.1e-10 39.5 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19727.1 - 0.00059 19.4 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG19727.1 - 0.0057 16.5 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein HATPase_c PF02518.26 OAG19728.1 - 3.8e-24 85.3 0.0 8.2e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG19728.1 - 3.3e-19 69.1 0.1 1e-18 67.5 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG19728.1 - 3.6e-11 42.9 0.4 2e-10 40.6 0.4 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG19728.1 - 0.0012 19.1 0.0 0.0048 17.2 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG19728.1 - 0.0024 18.1 0.0 0.072 13.4 0.0 2.9 2 0 0 2 2 2 1 PAS fold IF-2B PF01008.17 OAG19728.1 - 0.014 14.6 0.5 0.026 13.7 0.5 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family PMC2NT PF08066.12 OAG19728.1 - 0.06 14.1 1.4 0.9 10.3 0.3 2.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Peptidase_C78 PF07910.13 OAG19729.1 - 1.9e-60 204.0 0.0 2.7e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-RAG1 PF10426.9 OAG19729.1 - 0.018 15.2 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain MaoC_dehydratas PF01575.19 OAG19730.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain Trypan_PARP PF05887.11 OAG19730.1 - 1.1 9.3 5.4 0.61 10.1 3.3 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) vWA-TerF-like PF10138.9 OAG19731.1 - 0.00021 21.5 0.1 0.00067 19.8 0.1 1.7 1 1 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.16 OAG19731.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Copine CorA PF01544.18 OAG19733.1 - 1.3e-06 27.9 1.4 9.8e-06 25.1 0.3 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Nbl1_Borealin_N PF10444.9 OAG19733.1 - 0.23 11.1 1.8 0.6 9.8 0.4 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Cpn60_TCP1 PF00118.24 OAG19735.1 - 1.8e-86 290.7 13.5 3e-86 290.0 13.5 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 OAG19735.1 - 0.098 13.0 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator Cofilin_ADF PF00241.20 OAG19736.1 - 5e-38 129.6 0.2 5.6e-38 129.5 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.7 OAG19737.1 - 3.3e-48 163.8 0.6 5.2e-48 163.2 0.4 1.4 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 OAG19737.1 - 8.8e-21 73.3 0.3 1.4e-20 72.6 0.3 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 OAG19737.1 - 0.00062 19.5 0.4 0.0011 18.7 0.4 1.4 1 1 0 1 1 1 1 Ubiquitin family NOG1 PF06858.14 OAG19737.1 - 0.048 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Methyltr_RsmB-F PF01189.17 OAG19738.1 - 7.2e-76 254.3 0.0 1.3e-75 253.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAG19738.1 - 4.6e-09 36.7 0.0 1.4e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAG19738.1 - 0.024 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OAG19738.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 OAG19738.1 - 0.053 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) UPF0524 PF15823.5 OAG19738.1 - 0.37 10.2 2.1 0.78 9.1 2.1 1.6 1 0 0 1 1 1 0 UPF0524 of C3orf70 Sugar_tr PF00083.24 OAG19740.1 - 6.7e-124 414.2 19.5 8.2e-124 413.9 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19740.1 - 2.8e-17 62.7 31.2 7.4e-14 51.4 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 OAG19740.1 - 0.052 13.2 0.7 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MSP1b PF03429.13 OAG19740.1 - 0.19 9.8 0.6 0.42 8.7 0.4 1.5 2 0 0 2 2 2 0 Major surface protein 1B HGTP_anticodon PF03129.20 OAG19741.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain DnaJ PF00226.31 OAG19745.1 - 4.1e-13 49.3 0.5 1e-12 48.0 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Med3 PF11593.8 OAG19745.1 - 0.049 12.8 8.6 0.075 12.2 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PLN_propep PF16485.5 OAG19745.1 - 0.2 11.4 0.9 2.1 8.1 0.4 2.7 2 0 0 2 2 2 0 Protealysin propeptide bZIP_2 PF07716.15 OAG19746.1 - 8.3e-07 29.0 17.1 1.9e-06 27.8 16.6 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG19746.1 - 0.0053 16.8 16.5 0.017 15.2 16.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF3967 PF13152.6 OAG19746.1 - 0.1 12.4 4.8 0.22 11.3 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) YabA PF06156.13 OAG19746.1 - 0.1 13.2 3.7 2 9.1 6.5 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Di19_C PF14571.6 OAG19746.1 - 0.86 10.2 5.9 1 9.9 5.3 1.4 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal HET PF06985.11 OAG19747.1 - 1.2e-21 77.6 0.1 2.3e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.6 OAG19749.1 - 2.7e-26 93.2 0.0 4.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG19749.1 - 6.6e-16 58.5 0.1 1.2e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG19749.1 - 7.3e-05 22.6 0.0 0.00042 20.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG19749.1 - 0.051 12.9 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 OAG19749.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Abhydrolase_1 PF00561.20 OAG19750.1 - 7.2e-23 81.5 0.0 5.7e-22 78.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG19750.1 - 5.8e-12 46.7 0.0 1.1e-11 45.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG19750.1 - 1.9e-11 43.7 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG19750.1 - 0.00026 20.8 0.1 0.07 12.8 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 OAG19750.1 - 0.0059 15.3 0.0 0.046 12.4 0.0 1.9 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 OAG19750.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 OAG19750.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 OAG19750.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 OAG19750.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 OAG19750.1 - 0.031 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 OAG19750.1 - 0.13 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 OAG19750.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF4199 PF13858.6 OAG19753.1 - 0.025 15.0 0.6 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) RicinB_lectin_2 PF14200.6 OAG19754.1 - 2.6e-05 24.9 1.6 2.6e-05 24.9 0.3 1.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like HATPase_c PF02518.26 OAG19755.1 - 6.6e-26 91.0 0.0 1.6e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG19755.1 - 1e-24 86.9 0.1 2.3e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG19755.1 - 3.2e-16 59.1 3.3 3.5e-16 59.0 0.5 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAG19755.1 - 2.1e-15 56.9 0.1 4.3e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAG19755.1 - 1.2e-12 48.0 0.0 5.4e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG19755.1 - 7.6e-10 38.8 0.0 8.1e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OAG19755.1 - 9.2e-05 22.7 0.1 0.00038 20.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold BASP1 PF05466.12 OAG19756.1 - 0.56 10.2 6.4 0.71 9.8 6.4 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Pneumo_att_G PF05539.11 OAG19756.1 - 2.8 7.5 9.4 3 7.4 9.4 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Novirhabdo_Nv PF05554.11 OAG19757.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein SARAF PF06682.12 OAG19758.1 - 8.3e-107 357.7 2.2 9.8e-107 357.4 2.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PIG-X PF08320.12 OAG19759.1 - 1.5e-65 221.0 0.0 2.4e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 ThiF PF00899.21 OAG19760.1 - 8.8e-33 113.7 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 OAG19762.1 - 2.7e-08 33.2 1.8 3.3e-08 32.9 1.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG19762.1 - 1.6e-07 31.4 9.0 4.6e-07 29.8 9.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCC_BT PF18140.1 OAG19763.1 - 0.045 14.1 0.6 0.068 13.5 0.6 1.3 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain DPBB_1 PF03330.18 OAG19764.1 - 2.8e-09 37.1 0.6 9.3e-09 35.5 0.1 2.3 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 OAG19764.1 - 0.0055 16.7 0.3 0.012 15.6 0.3 1.5 1 0 0 1 1 1 1 Pollen allergen CHB_HEX_C PF03174.13 OAG19764.1 - 0.025 14.6 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR PF02012.20 OAG19764.1 - 0.045 13.7 2.3 0.11 12.6 0.1 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat InPase PF18823.1 OAG19764.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase INO80_Ies4 PF08193.11 OAG19764.1 - 0.35 10.8 5.5 0.77 9.7 5.5 1.5 1 0 0 1 1 1 0 INO80 complex subunit Ies4 PRCC PF10253.9 OAG19764.1 - 0.83 10.4 6.0 0.81 10.4 1.1 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PIG-F PF06699.11 OAG19765.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.0 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Bmt2 PF11968.8 OAG19766.1 - 1e-85 287.0 0.0 1.3e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 OAG19766.1 - 0.023 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_N PF04675.14 OAG19766.1 - 0.088 13.1 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 DNA ligase N terminus Ribosomal_L23eN PF03939.13 OAG19767.1 - 1.5e-21 76.4 6.0 3.1e-21 75.3 6.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAG19767.1 - 3.9e-13 49.6 0.4 3.9e-13 49.6 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 OAG19768.1 - 5e-22 77.3 0.4 6.4e-22 77.0 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PAZ_siRNAbind PF12212.8 OAG19768.1 - 0.2 11.5 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 PAZ domain Aa_trans PF01490.18 OAG19770.1 - 2.6e-59 201.0 26.7 3.1e-59 200.7 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 OAG19770.1 - 0.017 15.6 3.0 0.017 15.6 3.0 3.1 2 1 0 2 2 2 0 MerC mercury resistance protein eRF1_2 PF03464.15 OAG19771.1 - 7.6e-48 162.2 0.1 1.2e-47 161.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAG19771.1 - 1.2e-39 135.3 0.3 2.5e-39 134.2 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAG19771.1 - 7.5e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 OAG19771.1 - 6.9e-10 39.3 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 OAG19771.1 - 6.6e-09 36.1 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 OAG19772.1 - 1.5e-60 204.1 0.0 2.6e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 OAG19772.1 - 2.1e-06 27.4 0.0 6.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain tRNA-synt_2b PF00587.25 OAG19773.1 - 1.4e-33 116.3 0.0 2.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG19773.1 - 4.2e-19 68.8 7.1 9.6e-19 67.6 7.1 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3698 PF12479.8 OAG19773.1 - 0.058 13.9 0.1 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) Ras PF00071.22 OAG19774.1 - 9.9e-46 155.3 0.4 1.1e-45 155.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG19774.1 - 5.3e-15 55.7 0.2 7.5e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG19774.1 - 7.2e-08 32.1 0.0 7.7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG19774.1 - 6.3e-05 22.5 0.0 9.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG19774.1 - 0.00057 19.8 0.3 0.066 13.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAG19774.1 - 0.00064 19.3 0.1 0.0027 17.2 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG19774.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG19774.1 - 0.014 14.9 0.0 0.095 12.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 OAG19774.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 OAG19775.1 - 1.8e-62 211.3 10.4 3.4e-62 210.4 10.4 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 OAG19776.1 - 3e-82 275.1 0.0 4.2e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG19776.1 - 0.0025 17.3 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 OAG19777.1 - 1.2e-31 108.5 1.1 1.6e-31 108.2 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 OAG19777.1 - 0.012 15.7 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 PHD-finger Zn-ribbon_8 PF09723.10 OAG19777.1 - 0.039 14.1 0.9 0.087 13.0 0.9 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 OAG19777.1 - 0.055 13.4 0.4 0.086 12.8 0.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-LITAF-like PF10601.9 OAG19777.1 - 0.078 13.3 3.0 2.9 8.2 0.3 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-Sec23_Sec24 PF04810.15 OAG19777.1 - 0.11 12.5 1.1 3.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger YABBY PF04690.13 OAG19777.1 - 0.13 12.8 1.4 0.2 12.2 1.4 1.4 1 1 0 1 1 1 0 YABBY protein T4_baseplate PF12322.8 OAG19777.1 - 0.19 11.2 1.6 2.8 7.4 0.4 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zf-H2C2_2 PF13465.6 OAG19777.1 - 0.22 12.0 1.7 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG19777.1 - 0.38 11.7 2.4 2.1 9.4 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_CH_N PF12471.8 OAG19778.1 - 5.2e-93 310.2 0.0 7.8e-93 309.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAG19778.1 - 1.4e-17 63.7 0.0 2.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II NUDE_C PF04880.13 OAG19779.1 - 3 8.3 9.8 3.6 8.0 9.8 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ribosomal_S3Ae PF01015.18 OAG19780.1 - 1.9e-89 298.6 3.6 2.4e-89 298.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family NEMO PF11577.8 OAG19780.1 - 0.062 13.3 0.6 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO p450 PF00067.22 OAG19781.1 - 2.6e-05 23.2 0.0 0.00051 18.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Ham1p_like PF01725.16 OAG19782.1 - 5.4e-60 202.5 0.0 6.1e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 OAG19783.1 - 6.1e-27 94.7 0.3 1.5e-26 93.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG19783.1 - 5.3e-08 33.4 0.7 1.6e-06 28.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG19783.1 - 5.6e-07 29.8 0.0 2.4e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG19783.1 - 5.4e-06 26.8 0.2 1.3e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 OAG19783.1 - 6.3e-06 26.4 0.2 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.19 OAG19783.1 - 2.7e-05 24.1 0.8 0.01 15.7 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 OAG19783.1 - 0.00011 21.8 0.1 0.00038 20.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 OAG19783.1 - 0.00013 22.4 0.1 0.00042 20.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAG19783.1 - 0.00056 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 NTPase SKI PF01202.22 OAG19783.1 - 0.00072 19.7 0.1 0.012 15.8 0.1 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 OAG19783.1 - 0.0033 17.7 0.1 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 OAG19783.1 - 0.0036 17.0 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 OAG19783.1 - 0.0045 17.4 0.1 0.0065 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG19783.1 - 0.0051 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 OAG19783.1 - 0.0054 17.0 0.0 0.0094 16.2 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 OAG19783.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAG19783.1 - 0.011 15.8 0.1 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG19783.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein CR6_interact PF10147.9 OAG19783.1 - 0.015 15.0 1.8 0.02 14.6 1.8 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 UCMA PF17085.5 OAG19783.1 - 0.018 15.1 2.4 0.026 14.6 2.4 1.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Cytidylate_kin2 PF13189.6 OAG19783.1 - 0.031 14.4 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family RNA_helicase PF00910.22 OAG19783.1 - 0.035 14.5 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAG19783.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAG19783.1 - 0.062 13.6 0.6 0.11 12.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 OAG19783.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG19783.1 - 0.099 12.6 0.2 0.33 10.8 0.0 1.9 2 1 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 OAG19783.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 OAG19783.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 OAG19783.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 OAG19783.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OAG19783.1 - 0.2 11.4 2.1 0.8 9.4 1.0 2.2 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG19783.1 - 0.22 10.9 0.4 0.72 9.2 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NAP PF00956.18 OAG19784.1 - 8.7e-99 330.1 11.0 8.7e-99 330.1 11.0 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) WWE PF02825.20 OAG19784.1 - 1.7 9.3 3.6 4.8 7.9 0.1 2.7 3 0 0 3 3 3 0 WWE domain MFS_2 PF13347.6 OAG19785.1 - 7e-13 47.9 4.9 7e-13 47.9 4.9 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 OAG19785.1 - 2.4e-05 23.4 0.5 6e-05 22.1 0.6 1.7 1 1 0 1 1 1 1 MFS_1 like family BT1 PF03092.16 OAG19785.1 - 0.099 10.8 6.5 0.041 12.1 3.7 1.6 2 0 0 2 2 2 0 BT1 family Myosin_head PF00063.21 OAG19788.1 - 2.2e-261 868.9 0.1 2.2e-261 868.9 0.1 1.7 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 OAG19788.1 - 5.6e-27 94.0 2.9 2.9e-26 91.8 2.9 2.4 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 OAG19788.1 - 1.3e-13 49.4 22.6 0.00019 20.9 0.2 6.6 6 0 0 6 6 6 3 IQ calmodulin-binding motif Spc7 PF08317.11 OAG19788.1 - 8.4e-05 21.6 20.4 0.00018 20.5 20.4 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Myosin_N PF02736.19 OAG19788.1 - 8.4e-05 22.3 2.3 0.00025 20.8 2.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 OAG19788.1 - 0.0004 19.8 17.9 0.0004 19.8 17.9 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 OAG19788.1 - 0.004 17.6 0.0 0.02 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG19788.1 - 0.0063 16.8 2.3 0.018 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF812 PF05667.11 OAG19788.1 - 0.0086 15.0 25.5 0.018 13.9 25.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FPP PF05911.11 OAG19788.1 - 0.016 13.4 23.9 0.033 12.4 23.9 1.4 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 OAG19788.1 - 0.018 15.5 27.7 0.59 10.5 13.2 2.8 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 OAG19788.1 - 0.047 12.8 19.8 0.097 11.7 19.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Flp_N PF03930.14 OAG19788.1 - 0.084 12.9 2.1 0.15 12.0 0.5 2.3 2 0 0 2 2 1 0 Recombinase Flp protein N-terminus KASH_CCD PF14662.6 OAG19788.1 - 0.26 11.1 34.3 5.1 6.9 23.6 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 OAG19788.1 - 0.52 10.1 22.1 0.036 13.9 4.5 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 Herpes_BLRF2 PF05812.12 OAG19788.1 - 0.7 10.0 16.8 1.4 9.1 3.6 3.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF4407 PF14362.6 OAG19788.1 - 1.4 8.2 14.7 3 7.1 14.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 OAG19788.1 - 2.9 8.0 15.1 1.1 9.3 0.7 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ING PF12998.7 OAG19788.1 - 2.9 8.5 16.3 1.1 9.9 6.3 3.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding EMP24_GP25L PF01105.24 OAG19788.1 - 7 6.6 15.6 6.8 6.6 4.9 2.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD HET PF06985.11 OAG19789.1 - 1.3e-28 100.2 0.0 2.4e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAG19791.1 - 5.7e-15 55.7 0.1 2.5e-10 40.8 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG19791.1 - 7.2e-09 35.2 0.0 0.04 14.5 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 OAG19791.1 - 4.2e-07 30.4 0.2 0.0018 18.8 0.0 3.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG19791.1 - 1.3e-05 25.4 0.2 0.025 15.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG19791.1 - 2e-05 24.8 0.1 1.4 9.3 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) 2-Hacid_dh_C PF02826.19 OAG19792.1 - 3.3e-53 179.7 0.0 6.1e-53 178.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG19792.1 - 7.6e-36 122.7 0.1 9.9e-36 122.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG19792.1 - 0.00014 22.1 0.9 0.00028 21.1 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 OAG19792.1 - 0.0009 19.3 1.2 0.0014 18.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 OAG19792.1 - 0.02 14.5 0.7 0.068 12.7 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 OAG19792.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 ACT domain G6PD_C PF02781.16 OAG19793.1 - 1.5e-115 385.4 0.0 2.4e-115 384.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAG19793.1 - 1.5e-60 204.8 0.0 2.8e-60 204.0 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain TruD PF01142.18 OAG19793.1 - 0.044 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) Ribosomal_L35Ae PF01247.18 OAG19794.1 - 1.6e-43 146.8 0.5 1.8e-43 146.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAG19794.1 - 1.5e-05 25.1 0.1 0.011 16.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.25 OAG19795.1 - 0.07 12.5 0.5 0.32 10.3 0.1 2.1 1 1 1 2 2 2 0 Protein kinase domain RhoGEF PF00621.20 OAG19796.1 - 1.9e-07 31.5 0.0 4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Helo_like_N PF17111.5 OAG19796.1 - 0.0016 17.8 1.2 0.0016 17.8 1.2 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Striatin PF08232.12 OAG19797.1 - 1.2e-44 152.6 4.2 1.2e-44 152.6 4.2 2.8 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 OAG19797.1 - 2.7e-24 84.9 21.2 0.00013 22.6 0.2 8.5 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG19797.1 - 9.4e-05 22.6 0.0 2.4 8.5 0.0 4.5 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain KLRAQ PF10205.9 OAG19797.1 - 0.02 15.1 2.3 0.058 13.6 2.3 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein PXA PF02194.15 OAG19797.1 - 4.9 7.1 6.2 0.25 11.3 0.5 1.7 2 0 0 2 2 2 0 PXA domain zf-dskA_traR PF01258.17 OAG19798.1 - 0.12 12.3 0.4 0.12 12.3 0.4 1.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Histone PF00125.24 OAG19799.1 - 1.3e-16 61.2 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAG19799.1 - 8.6e-13 47.8 0.1 2.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAG19799.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EamA PF00892.20 OAG19801.1 - 2e-07 31.3 28.5 4.3e-06 26.9 7.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OAG19801.1 - 0.0091 15.4 21.0 0.2 11.0 21.0 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 OAG19801.1 - 0.97 10.1 17.6 0.53 11.0 4.6 2.8 3 0 0 3 3 3 0 Small Multidrug Resistance protein Phosducin PF02114.16 OAG19803.1 - 2.8e-05 23.2 0.1 3.6e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 OAG19803.1 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ARD PF03079.14 OAG19804.1 - 2.5e-48 164.2 0.1 2.9e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OAG19804.1 - 9.4e-11 41.3 0.1 1.6e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG19804.1 - 2e-07 31.0 0.1 2.6e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG19804.1 - 8.2e-05 22.2 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG19804.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Lyx_isomer PF07385.12 OAG19804.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 D-lyxose isomerase Cupin_6 PF12852.7 OAG19804.1 - 0.046 13.5 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Cupin DMSP_lyase PF16867.5 OAG19804.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase AAA_18 PF13238.6 OAG19805.1 - 0.55 10.8 2.7 1.1 9.8 0.8 2.4 2 0 0 2 2 2 0 AAA domain DUF2951 PF11166.8 OAG19805.1 - 2.1 8.6 4.2 2 8.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HET PF06985.11 OAG19806.1 - 4.6e-27 95.2 0.0 9.4e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 OAG19807.1 - 0.0087 15.9 0.9 0.021 14.7 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG19807.1 - 0.067 13.1 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 F-box domain Brix PF04427.18 OAG19809.1 - 4.3e-39 134.6 0.1 5.9e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 OAG19810.1 - 1.9e-63 214.3 1.6 1.9e-63 214.3 1.6 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 OAG19810.1 - 4.3e-47 159.8 21.5 4.3e-47 159.8 21.5 4.1 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 OAG19810.1 - 1.9e-19 70.1 0.0 4.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG19810.1 - 1.5e-06 28.3 0.0 1.5e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG19810.1 - 0.0028 16.9 0.0 0.0028 16.9 0.0 3.2 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAG19810.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1117 PF06547.12 OAG19810.1 - 3.9 8.0 5.2 26 5.4 5.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) TPT PF03151.16 OAG19811.1 - 6.1e-10 38.9 15.3 8.5e-10 38.5 15.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG19811.1 - 5.1e-05 23.4 10.1 5.1e-05 23.4 10.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Macro PF01661.21 OAG19812.1 - 1.2e-36 125.3 0.0 2.3e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 Macro domain MarR PF01047.22 OAG19812.1 - 1.4e-05 25.0 0.0 0.69 9.9 0.0 4.2 4 0 0 4 4 4 2 MarR family Rrf2 PF02082.20 OAG19812.1 - 0.00015 22.0 0.0 0.58 10.5 0.0 3.8 3 0 0 3 3 3 1 Transcriptional regulator RPA_C PF08784.11 OAG19812.1 - 0.00062 20.4 0.0 2.6 8.8 0.0 3.8 3 0 0 3 3 3 1 Replication protein A C terminal MarR_2 PF12802.7 OAG19812.1 - 0.00079 19.3 0.1 2.4 8.1 0.0 3.4 3 0 0 3 3 3 2 MarR family TrmB PF01978.19 OAG19812.1 - 0.018 14.9 0.0 6.7 6.7 0.0 3.7 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 OAG19812.1 - 0.019 14.8 0.0 19 5.1 0.0 3.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF2218 PF09981.9 OAG19812.1 - 0.028 14.8 0.4 0.16 12.4 0.0 2.5 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2218) FeoC PF09012.10 OAG19812.1 - 0.074 13.1 0.0 8.4 6.6 0.0 3.2 3 0 0 3 3 3 0 FeoC like transcriptional regulator HTH_27 PF13463.6 OAG19812.1 - 0.09 13.3 0.0 9.7 6.8 0.0 3.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain HemN_C PF06969.16 OAG19812.1 - 0.11 12.6 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 HemN C-terminal domain GntR PF00392.21 OAG19812.1 - 0.11 12.2 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family BLACT_WH PF17778.1 OAG19812.1 - 0.14 12.1 0.2 0.51 10.4 0.2 1.9 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain PadR PF03551.14 OAG19812.1 - 0.16 11.9 0.0 8.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family zf-C2H2_4 PF13894.6 OAG19812.1 - 1.4 9.9 8.0 31 5.8 0.0 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger HeLo PF14479.6 OAG19813.1 - 0.029 14.2 0.3 0.57 10.0 0.9 2.5 3 0 0 3 3 3 0 Prion-inhibition and propagation Ima1_N PF09779.9 OAG19813.1 - 0.071 14.0 1.4 0.18 12.7 1.4 1.7 1 0 0 1 1 1 0 Ima1 N-terminal domain COMM_domain PF07258.14 OAG19813.1 - 0.14 12.3 0.3 0.47 10.6 0.3 2.0 1 0 0 1 1 1 0 COMM domain SMI1_KNR4 PF09346.10 OAG19814.1 - 9.3e-32 110.2 0.0 4.3e-31 108.0 0.0 2.0 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) adh_short PF00106.25 OAG19815.1 - 3.9e-10 39.5 0.0 4.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19815.1 - 9.4e-07 28.6 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19815.1 - 1.8e-06 28.0 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG19816.1 - 2.5e-35 121.7 1.5 3.2e-35 121.4 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19816.1 - 1.2e-32 113.4 0.5 1.5e-32 113.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19816.1 - 1.8e-12 47.6 0.5 2.4e-12 47.2 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG19816.1 - 7.6e-05 22.3 0.1 0.00078 19.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG19816.1 - 0.035 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 OAG19816.1 - 0.094 12.1 2.2 9.3 5.5 2.2 2.2 1 1 0 1 1 1 0 ThiF family Peroxin-3 PF04882.12 OAG19819.1 - 1.3e-167 558.6 0.2 1.5e-167 558.4 0.2 1.0 1 0 0 1 1 1 1 Peroxin-3 Glyco_transf_8 PF01501.20 OAG19820.1 - 4.8e-14 52.5 0.6 1.8e-13 50.7 0.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OAG19820.1 - 0.0063 16.5 0.9 0.011 15.7 0.9 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Spore_II_R PF09551.10 OAG19821.1 - 1.3 9.4 5.3 2.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) F-box-like PF12937.7 OAG19822.1 - 0.00055 19.8 0.0 0.0022 17.9 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF905 PF06006.12 OAG19822.1 - 0.085 12.9 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Pro_CA PF00484.19 OAG19823.1 - 5.1e-12 46.3 1.0 6.1e-11 42.9 1.0 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 OAG19824.1 - 2.1e-25 89.8 0.4 4.8e-25 88.7 0.4 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG19824.1 - 1.7e-17 63.5 0.4 2.7e-17 62.8 0.4 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG19824.1 - 7.9e-17 62.6 0.0 1.1e-16 62.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAG19824.1 - 2e-06 27.0 0.0 4.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 OAG19824.1 - 0.00053 19.0 0.0 0.00082 18.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 OAG19824.1 - 0.0038 16.8 0.0 0.02 14.5 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG19824.1 - 0.0078 15.7 0.2 0.038 13.5 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG19824.1 - 0.013 15.3 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 OAG19824.1 - 0.013 14.8 0.1 0.056 12.8 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1057 PF06342.12 OAG19824.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 OAG19824.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 OAG19824.1 - 0.023 14.8 0.0 0.034 14.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 OAG19824.1 - 0.037 13.8 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAG19824.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF1664 PF07889.12 OAG19825.1 - 0.024 14.7 0.1 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ferritin PF00210.24 OAG19825.1 - 0.056 13.4 0.0 1.9 8.4 0.1 2.6 2 1 1 3 3 3 0 Ferritin-like domain Abhydrolase_3 PF07859.13 OAG19826.1 - 1.4e-49 168.8 0.0 2.1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG19826.1 - 1e-13 51.1 0.1 4.5e-13 48.9 0.1 1.9 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAG19826.1 - 0.00055 20.6 0.0 0.0009 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG19826.1 - 0.012 15.0 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family EzrA PF06160.12 OAG19826.1 - 0.15 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA adh_short_C2 PF13561.6 OAG19827.1 - 8.7e-49 166.2 2.2 1.1e-48 165.8 2.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19827.1 - 1.6e-39 135.4 1.4 2e-39 135.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_43 PF04616.14 OAG19828.1 - 2.7e-43 148.3 7.0 3.1e-43 148.1 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sushi PF00084.20 OAG19829.1 - 0.1 13.2 0.1 0.63 10.7 0.0 2.0 1 1 0 2 2 2 0 Sushi repeat (SCR repeat) Peptidase_M13_N PF05649.13 OAG19830.1 - 1.6e-99 334.2 0.0 2.4e-99 333.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAG19830.1 - 5.1e-61 205.8 1.3 1e-60 204.9 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M13 Bac_rhamnosid6H PF17389.2 OAG19831.1 - 5.4e-93 311.9 0.0 7.2e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OAG19831.1 - 3.2e-46 157.3 0.0 5.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OAG19831.1 - 1.8e-20 72.8 0.0 5.7e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OAG19831.1 - 2.5e-13 49.6 0.0 6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 OAG19831.1 - 0.0076 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Sugar_tr PF00083.24 OAG19832.1 - 8.8e-105 351.2 19.8 1e-104 351.0 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG19832.1 - 3e-27 95.5 30.2 3e-25 88.9 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAG19832.1 - 0.00022 20.2 3.4 0.00061 18.8 0.9 2.2 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM DUF4706 PF15797.5 OAG19834.1 - 0.026 15.0 1.0 0.088 13.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) ATG16 PF08614.11 OAG19834.1 - 0.031 14.5 6.1 0.05 13.8 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Glyco_hydro_35 PF01301.19 OAG19835.1 - 1.2e-92 310.9 0.5 1.8e-92 310.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 OAG19835.1 - 9.2e-62 208.1 5.0 1.6e-61 207.3 5.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 OAG19835.1 - 6.3e-53 178.2 7.6 2.3e-30 105.5 0.1 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 OAG19835.1 - 3.3e-14 52.2 0.1 1.1e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Atg14 PF10186.9 OAG19836.1 - 0.35 9.9 2.8 0.68 9.0 2.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 OAG19836.1 - 0.84 9.2 5.3 0.59 9.7 1.9 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase LPD5 PF18799.1 OAG19837.1 - 0.014 15.8 2.4 0.021 15.3 2.4 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 KMP11 PF03037.16 OAG19837.1 - 0.12 13.1 3.7 0.21 12.4 3.7 1.3 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 BCAS2 PF05700.11 OAG19838.1 - 0.0026 17.5 2.4 0.0053 16.5 2.4 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CVNH PF08881.10 OAG19841.1 - 1.6e-27 96.1 0.2 1.8e-27 96.0 0.2 1.0 1 0 0 1 1 1 1 CVNH domain F-box-like_2 PF13013.6 OAG19844.1 - 0.011 15.7 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 F-box-like domain Thump_like PF18096.1 OAG19844.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 THUMP domain-like HlyIII PF03006.20 OAG19845.1 - 2.3e-51 174.7 18.5 2.9e-51 174.4 18.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.6 OAG19845.1 - 0.25 10.8 9.6 0.12 11.9 6.9 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein PRA1 PF03208.19 OAG19845.1 - 3.1 7.4 10.6 0.073 12.7 2.2 2.5 4 0 0 4 4 4 0 PRA1 family protein TPR_14 PF13428.6 OAG19846.1 - 1.9e-13 50.0 10.8 0.27 12.2 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG19846.1 - 2.8e-08 33.3 12.7 0.79 10.0 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG19846.1 - 4.4e-08 32.6 0.9 2.1 8.3 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG19846.1 - 6e-08 33.1 1.9 0.37 11.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG19846.1 - 5.3e-05 23.3 0.1 6.3 7.4 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG19846.1 - 0.0003 20.8 3.3 5.3 7.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG19846.1 - 0.14 12.9 3.1 2.1 9.2 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SelP_N PF04592.14 OAG19846.1 - 0.77 9.1 3.2 1.4 8.3 3.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPR_12 PF13424.6 OAG19846.1 - 1.2 9.5 12.7 1.5 9.2 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG19846.1 - 4 8.2 22.7 0.15 12.7 0.4 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat RIX1 PF08167.12 OAG19847.1 - 9.4e-58 195.1 5.8 1.9e-57 194.0 5.8 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HET PF06985.11 OAG19849.1 - 5.3e-09 36.6 8.3 9.6e-08 32.5 1.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DMAP1_like PF17024.5 OAG19849.1 - 0.0037 17.4 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative DMAP1-like DUF3012 PF11216.8 OAG19849.1 - 0.017 15.1 1.4 0.033 14.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) zf-RNPHF PF08080.12 OAG19849.1 - 0.21 11.6 1.1 1.3 9.0 0.5 2.2 2 0 0 2 2 2 0 RNPHF zinc finger Astacin PF01400.24 OAG19850.1 - 5.3e-08 32.7 0.5 9.4e-08 31.9 0.5 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OAG19850.1 - 0.0021 18.0 2.5 0.0033 17.3 2.5 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 OAG19850.1 - 0.013 15.6 0.3 0.022 14.9 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAG19850.1 - 0.015 15.8 0.6 0.03 14.8 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG19850.1 - 0.023 14.4 0.2 0.036 13.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 OAG19850.1 - 0.024 14.3 0.3 0.041 13.5 0.3 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 OAG19850.1 - 0.079 12.8 1.5 0.14 12.0 1.5 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OAG19850.1 - 0.38 9.9 1.6 0.61 9.2 1.6 1.2 1 0 0 1 1 1 0 Met-zincin UQ_con PF00179.26 OAG19851.1 - 1.3e-46 157.7 0.1 1.6e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG19851.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 RWD domain Promethin PF16015.5 OAG19852.1 - 6.8e-28 96.7 11.5 8.5e-28 96.4 11.5 1.1 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 OAG19852.1 - 1 8.0 7.5 4.4 6.0 7.9 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 OAG19852.1 - 3.9 5.7 6.7 5 5.3 6.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RNA_pol_I_A49 PF06870.12 OAG19853.1 - 1.6e-91 307.0 0.2 2e-91 306.8 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor PI3K_P85_iSH2 PF16454.5 OAG19853.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Seryl_tRNA_N PF02403.22 OAG19853.1 - 5.8 7.2 8.4 0.94 9.7 2.1 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Herpes_LMP1 PF05297.11 OAG19854.1 - 3.2 6.8 4.6 3.5 6.7 4.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DER1 PF04511.15 OAG19855.1 - 9.9e-27 94.1 5.5 7.1e-13 48.9 1.0 2.1 2 0 0 2 2 2 2 Der1-like family zf-4CXXC_R1 PF10497.9 OAG19856.1 - 0.018 15.3 4.8 0.031 14.5 4.8 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Elf1 PF05129.13 OAG19856.1 - 0.31 11.1 6.3 0.55 10.3 6.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SOG2 PF10428.9 OAG19856.1 - 2 7.6 10.9 2.4 7.3 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pet127 PF08634.10 OAG19858.1 - 2e-114 381.7 1.0 3e-114 381.1 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 HTH_16 PF12645.7 OAG19858.1 - 0.036 14.1 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2514 PF10721.9 OAG19858.1 - 2 8.4 11.8 6 6.9 11.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) LRR_6 PF13516.6 OAG19859.1 - 0.00053 19.8 7.8 13 6.2 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich repeat PH PF00169.29 OAG19859.1 - 0.0026 18.2 0.0 0.015 15.8 0.0 2.3 2 1 0 2 2 2 1 PH domain LRR_1 PF00560.33 OAG19859.1 - 0.22 12.2 9.6 7.8 7.5 0.1 7.0 9 0 0 9 9 9 0 Leucine Rich Repeat UBA_4 PF14555.6 OAG19860.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Osmo_CC PF08946.10 OAG19860.1 - 0.0057 16.9 0.3 12 6.3 0.0 3.4 3 0 0 3 3 3 2 Osmosensory transporter coiled coil ASD2 PF08687.11 OAG19860.1 - 0.026 14.1 0.7 0.026 14.1 0.7 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HSCB_C PF07743.13 OAG19860.1 - 0.067 13.7 0.8 11 6.5 0.0 2.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Fib_alpha PF08702.10 OAG19860.1 - 0.11 12.7 3.3 0.17 12.0 1.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5595 PF18077.1 OAG19860.1 - 0.15 12.2 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Dicty_REP PF05086.12 OAG19860.1 - 5 5.0 6.0 0.41 8.6 1.3 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF948 PF06103.11 OAG19860.1 - 5 7.4 5.2 13 6.1 0.0 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) adh_short_C2 PF13561.6 OAG19861.1 - 3.6e-54 183.8 0.2 4.5e-54 183.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG19861.1 - 2.7e-47 160.7 1.1 3.3e-47 160.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG19861.1 - 8.9e-12 45.3 0.2 1.2e-11 44.9 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG19861.1 - 0.0029 17.0 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OAG19861.1 - 0.031 14.1 1.2 0.059 13.3 0.8 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG19861.1 - 0.039 13.4 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_61 PF03443.14 OAG19863.1 - 2e-44 152.0 1.6 2.5e-44 151.7 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF410 PF04190.13 OAG19865.1 - 1.4e-86 290.5 0.0 1.6e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Sacchrp_dh_C PF16653.5 OAG19866.1 - 7.8e-94 314.7 0.0 1.2e-93 314.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG19866.1 - 1.8e-25 89.7 1.1 2.9e-25 89.0 1.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG19866.1 - 1.4e-09 38.1 0.2 3e-09 37.0 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAG19866.1 - 3.1e-06 27.2 1.4 4.7e-06 26.6 1.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 OAG19866.1 - 0.0025 17.4 0.6 0.024 14.2 0.4 2.6 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 OAG19866.1 - 0.013 15.9 0.3 0.028 14.9 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.13 OAG19866.1 - 0.018 14.6 0.5 0.031 13.9 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 OAG19866.1 - 0.024 14.1 0.2 0.046 13.2 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.22 OAG19866.1 - 0.028 15.2 0.1 0.054 14.3 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 OAG19866.1 - 0.031 14.5 0.9 0.054 13.8 0.9 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 OAG19866.1 - 0.056 12.4 0.1 0.081 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 OAG19866.1 - 0.75 9.9 4.1 0.42 10.8 0.9 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sec15 PF04091.12 OAG19867.1 - 1.3e-102 343.5 2.5 1.3e-102 343.5 2.5 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 OAG19867.1 - 1.8e-05 24.8 4.0 8e-05 22.7 4.0 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 OAG19867.1 - 9.2e-05 22.4 3.0 0.00056 19.8 3.0 2.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OAG19867.1 - 0.0056 16.0 4.7 0.015 14.6 4.7 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex ApoLp-III PF07464.11 OAG19867.1 - 0.024 14.7 6.6 0.14 12.3 1.3 3.7 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Mre11_DNA_bind PF04152.14 OAG19867.1 - 0.1 12.9 1.8 0.97 9.7 0.0 3.1 2 1 1 3 3 3 0 Mre11 DNA-binding presumed domain COG5 PF10392.9 OAG19867.1 - 0.22 11.7 6.4 0.086 13.0 0.8 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Vps51 PF08700.11 OAG19867.1 - 0.76 9.9 5.8 0.26 11.4 0.6 2.9 2 1 1 3 3 3 0 Vps51/Vps67 Sec5 PF15469.6 OAG19867.1 - 1.8 8.3 11.4 0.19 11.5 3.9 2.9 3 1 0 3 3 3 0 Exocyst complex component Sec5 Baculo_PEP_C PF04513.12 OAG19867.1 - 2.2 8.3 15.9 0.036 14.1 4.4 3.6 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_2 PF04059.12 OAG19872.1 - 9.9e-30 102.6 0.1 2.6e-29 101.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 OAG19872.1 - 1.5e-07 31.2 0.5 0.022 14.5 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAI1 PF08652.11 OAG19874.1 - 5.2e-23 81.0 0.0 9.2e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Abhydrolase_5 PF12695.7 OAG19876.1 - 0.0039 17.0 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAG19876.1 - 0.023 14.5 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG19876.1 - 0.085 12.7 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Gti1_Pac2 PF09729.9 OAG19878.1 - 1.2e-55 188.4 0.1 1.6e-55 188.0 0.1 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Methyltransf_2 PF00891.18 OAG19880.1 - 2.5e-15 56.3 0.0 3.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HET PF06985.11 OAG19882.1 - 3e-27 95.8 0.0 6.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAG19883.1 - 9.2e-47 157.5 13.0 1.9e-09 38.0 0.3 6.9 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG19883.1 - 1.5e-44 149.5 18.9 2.2e-09 37.4 0.0 9.0 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG19883.1 - 1.5e-35 121.1 15.6 7e-06 26.5 0.2 10.3 3 3 6 10 10 10 8 Ankyrin repeats (many copies) Pkinase PF00069.25 OAG19883.1 - 2.1e-35 122.4 0.0 3.1e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 OAG19883.1 - 2.3e-29 100.5 28.0 0.00067 20.0 0.1 14.2 14 0 0 14 14 14 7 Ankyrin repeat Pkinase_Tyr PF07714.17 OAG19883.1 - 5.5e-28 98.0 0.0 1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 OAG19883.1 - 5e-24 81.8 17.3 0.018 15.5 0.0 12.0 14 0 0 14 14 14 5 Ankyrin repeat RIO1 PF01163.22 OAG19883.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PMP22_Claudin PF00822.20 OAG19884.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family ABC_membrane PF00664.23 OAG19887.1 - 7.4e-86 288.2 22.8 2.1e-45 155.5 8.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG19887.1 - 2.7e-52 176.9 0.0 8.3e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG19887.1 - 1.1e-08 34.8 4.8 0.0023 17.4 0.1 4.3 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAG19887.1 - 2.9e-06 27.3 0.7 0.14 12.2 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG19887.1 - 8e-06 26.3 1.1 0.064 13.6 0.1 2.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAG19887.1 - 4.8e-05 23.0 0.1 0.32 10.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG19887.1 - 0.00017 21.5 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OAG19887.1 - 0.0007 20.2 0.1 0.16 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 OAG19887.1 - 0.001 19.0 0.5 0.54 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG19887.1 - 0.013 15.2 0.9 0.64 9.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG19887.1 - 0.014 15.5 0.9 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 OAG19887.1 - 0.022 15.0 2.1 4.4 7.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 OAG19887.1 - 0.036 13.6 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG19887.1 - 0.037 13.7 0.1 8.4 6.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUP PF00674.18 OAG19887.1 - 0.051 13.7 0.5 0.21 11.7 0.5 2.1 1 0 0 1 1 1 0 DUP family Roc PF08477.13 OAG19887.1 - 0.081 13.1 0.8 45 4.3 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase 60KD_IMP PF02096.20 OAG19887.1 - 0.14 12.0 3.4 0.38 10.6 3.4 1.7 1 0 0 1 1 1 0 60Kd inner membrane protein Zeta_toxin PF06414.12 OAG19887.1 - 0.18 11.1 0.1 17 4.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2841 PF11001.8 OAG19889.1 - 3.3e-17 62.7 0.1 5.8e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SAC3_GANP PF03399.16 OAG19890.1 - 1.5e-79 267.4 4.9 4.1e-79 266.0 4.9 1.7 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAG19890.1 - 3.6e-05 23.8 0.1 0.00073 19.5 0.1 2.6 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family FancD2 PF14631.6 OAG19890.1 - 1.6 6.0 13.2 3.1 5.1 13.2 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease ABC_tran PF00005.27 OAG19891.1 - 6.7e-50 169.2 0.0 1.4e-30 106.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG19891.1 - 4.9e-43 147.7 19.8 2.2e-32 112.8 2.2 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG19891.1 - 1.8e-09 37.4 0.1 0.075 12.5 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG19891.1 - 2.9e-06 26.9 0.1 0.065 13.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG19891.1 - 7.9e-06 26.2 0.1 0.97 9.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OAG19891.1 - 1.2e-05 25.8 0.0 0.19 12.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG19891.1 - 0.00014 22.4 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG19891.1 - 0.00097 19.0 2.7 16 5.2 0.0 4.3 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG19891.1 - 0.001 18.8 0.2 2 8.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAG19891.1 - 0.0025 17.6 0.1 2.9 7.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 OAG19891.1 - 0.0029 17.5 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 OAG19891.1 - 0.0042 16.3 0.0 4.1 6.5 0.0 3.4 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 OAG19891.1 - 0.005 16.8 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.6 OAG19891.1 - 0.011 16.0 0.2 2.7 8.3 0.0 3.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 OAG19891.1 - 0.014 15.5 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG19891.1 - 0.02 15.0 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG19891.1 - 0.021 14.5 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAG19891.1 - 0.024 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OAG19891.1 - 0.047 14.1 0.0 9.6 6.6 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG19891.1 - 0.053 12.8 0.3 1.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 OAG19891.1 - 0.061 12.9 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG19891.1 - 0.089 11.8 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 OAG19891.1 - 0.09 12.9 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 OAG19891.1 - 0.11 12.8 0.0 20 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DNase_NucA_NucB PF14040.6 OAG19891.1 - 0.2 12.1 0.4 0.53 10.7 0.2 1.8 2 0 0 2 2 1 0 Deoxyribonuclease NucA/NucB Adeno_IVa2 PF02456.15 OAG19891.1 - 0.22 10.3 0.1 0.69 8.6 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein FAD_binding_3 PF01494.19 OAG19892.1 - 1.5e-16 60.6 0.1 1.2e-14 54.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 OAG19893.1 - 1.1e-09 37.7 19.3 1.1e-09 37.7 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_DMAT PF11991.8 OAG19894.1 - 5e-34 118.3 0.0 6.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Aminotran_1_2 PF00155.21 OAG19895.1 - 9.3e-53 179.7 0.0 1.2e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.14 OAG19896.1 - 1.4e-28 99.5 0.2 1.9e-28 99.1 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_3_C PF01915.22 OAG19897.1 - 3.2e-45 154.6 0.0 4e-44 151.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG19897.1 - 2e-42 145.7 0.0 3.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG19897.1 - 2.3e-22 78.9 0.1 4.8e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG19897.1 - 6.1e-15 55.3 0.2 1.1e-14 54.5 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Malate_DH PF12434.8 OAG19897.1 - 0.63 10.1 2.2 1.8 8.7 2.2 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme PhyH PF05721.13 OAG19898.1 - 8.9e-15 55.5 0.0 1.3e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG19898.1 - 0.0078 16.6 0.0 0.017 15.5 0.0 1.7 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.19 OAG19899.1 - 3.6e-10 39.6 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG19899.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase UDPGT PF00201.18 OAG19900.1 - 2.8e-19 69.3 0.8 3.5e-19 69.0 0.1 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG19900.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Gcd10p PF04189.13 OAG19901.1 - 4.1e-120 400.4 0.0 5.4e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family MINDY_DUB PF04424.13 OAG19902.1 - 2.1e-25 89.0 0.0 3.7e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase AA_kinase PF00696.28 OAG19904.1 - 1.3e-38 133.0 0.1 1.8e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 OAG19904.1 - 4.8e-09 35.9 0.9 3.7e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 OAG19904.1 - 5.7e-08 32.4 0.5 3.3e-06 26.7 0.1 2.7 2 0 0 2 2 2 1 ACT domain HATPase_c PF02518.26 OAG19905.1 - 1.6e-23 83.4 0.0 2.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG19905.1 - 3.8e-23 81.8 0.1 7.2e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG19905.1 - 1.5e-09 37.7 0.0 3.9e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAG19905.1 - 1.7e-09 37.8 0.0 1.2e-06 28.7 0.0 3.5 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 OAG19905.1 - 2.4e-06 27.8 0.0 0.016 15.5 0.0 3.3 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 OAG19905.1 - 0.0035 17.3 0.0 1.1 9.4 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OAG19905.1 - 0.0069 16.4 0.0 0.039 14.0 0.0 2.5 1 0 0 1 1 1 1 PAS fold Podoplanin PF05808.11 OAG19906.1 - 6.3e-05 23.1 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 OAG19906.1 - 0.036 13.5 0.2 0.036 13.5 0.2 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CPSase_sm_chain PF00988.22 OAG19906.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain GH131_N PF18271.1 OAG19907.1 - 4.3e-62 210.1 3.0 6.2e-62 209.6 3.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain 2OG-FeII_Oxy PF03171.20 OAG19908.1 - 5.9e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG19908.1 - 3.5e-16 60.0 0.0 6.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Beta-lactamase PF00144.24 OAG19911.1 - 8.9e-40 136.9 0.0 1.2e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAG19911.1 - 0.014 14.8 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Esterase_phd PF10503.9 OAG19913.1 - 3.9e-06 26.5 0.0 7.4e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG19913.1 - 0.00014 21.4 0.0 0.0043 16.6 0.0 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAG19913.1 - 0.00049 18.9 0.0 0.012 14.3 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OAG19913.1 - 0.0019 18.0 0.0 0.004 17.0 0.0 1.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OAG19913.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.7 OAG19914.1 - 0.0082 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2013 PF09431.10 OAG19914.1 - 0.12 12.5 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) RAP1 PF07218.11 OAG19915.1 - 0.0033 15.8 5.9 0.0037 15.6 5.4 1.3 1 1 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF1972 PF09314.11 OAG19915.1 - 0.0088 15.6 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1972) MmgE_PrpD PF03972.14 OAG19915.1 - 0.031 12.8 0.1 0.043 12.4 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family F-box-like PF12937.7 OAG19916.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.18 OAG19917.1 - 8.5e-07 29.0 14.4 1.5e-06 28.2 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG19918.1 - 2.3e-24 85.9 0.1 2.9e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19918.1 - 1.2e-11 44.6 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG19918.1 - 6e-08 32.5 0.0 0.0036 16.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG19918.1 - 6.4e-05 22.9 0.2 0.00056 19.9 0.1 2.0 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 OAG19918.1 - 0.00057 19.4 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG19918.1 - 0.0033 17.3 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG19918.1 - 0.098 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family EPL1 PF10513.9 OAG19919.1 - 3.4e-27 95.7 0.1 9e-27 94.4 0.1 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like Latarcin PF10279.9 OAG19919.1 - 0.3 11.5 4.5 0.53 10.7 2.1 2.3 2 0 0 2 2 2 0 Latarcin precursor SET PF00856.28 OAG19920.1 - 8.5e-22 78.3 0.0 1.8e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OAG19920.1 - 3.3e-08 34.3 0.2 9.2e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.25 OAG19921.1 - 3.5e-81 272.9 0.0 4e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OAG19921.1 - 0.0091 15.7 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus SGL PF08450.12 OAG19922.1 - 3.5e-07 30.1 0.6 9.5e-06 25.4 0.3 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAG19922.1 - 0.0011 18.9 0.1 0.9 9.7 0.1 3.2 3 0 0 3 3 3 2 NHL repeat Pkinase PF00069.25 OAG19923.1 - 2.3e-22 79.6 0.0 3.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19923.1 - 4.9e-07 29.3 0.0 8.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gly_transf_sug PF04488.15 OAG19924.1 - 1.1e-20 74.0 0.0 2.7e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG19924.1 - 0.26 10.5 1.4 0.88 8.8 0.2 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Ank_2 PF12796.7 OAG19925.1 - 3.6e-11 43.5 0.8 3.3e-07 30.8 0.2 3.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) HET PF06985.11 OAG19925.1 - 7.2e-10 39.4 11.5 7.4e-09 36.1 7.4 3.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 OAG19925.1 - 1.2e-07 31.8 0.9 2.4e-06 27.7 0.1 2.8 2 1 1 3 3 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 OAG19925.1 - 6.1e-05 23.0 0.1 0.00019 21.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 OAG19925.1 - 6.9e-05 23.3 0.1 0.00038 21.0 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG19925.1 - 0.00042 20.6 0.0 0.027 15.0 0.0 3.9 4 0 0 4 4 3 1 Ankyrin repeat KAP_NTPase PF07693.14 OAG19925.1 - 0.0007 18.9 0.3 0.015 14.5 0.0 2.6 2 1 1 3 3 3 1 KAP family P-loop domain Ank PF00023.30 OAG19925.1 - 0.0036 17.7 0.1 0.1 13.1 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 OAG19925.1 - 0.0039 17.5 0.0 0.017 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG19925.1 - 0.0088 16.4 0.6 0.05 14.0 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 OAG19925.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG19925.1 - 0.078 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG19925.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA PF00004.29 OAG19925.1 - 0.15 12.5 0.2 0.74 10.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG19925.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AMPK1_CBM PF16561.5 OAG19927.1 - 9.7e-24 83.4 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OAG19927.1 - 2.3e-23 82.2 1.0 2.3e-23 82.2 1.0 2.7 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain HET PF06985.11 OAG19928.1 - 1.9e-29 102.9 0.0 2.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 OAG19929.1 - 1.7e-40 139.1 0.1 2.1e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG19929.1 - 0.00022 20.8 0.0 0.00041 19.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG19929.1 - 0.017 14.0 0.2 0.042 12.7 0.2 1.6 1 1 0 1 1 1 0 Carboxylesterase family DUF2920 PF11144.8 OAG19929.1 - 0.034 13.3 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DUF3040 PF11239.8 OAG19930.1 - 0.0065 16.7 1.8 21 5.5 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3040) Sugarporin_N PF11471.8 OAG19930.1 - 0.011 15.7 3.6 0.011 15.7 3.6 2.8 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension Caskin-Pro-rich PF16907.5 OAG19930.1 - 0.022 15.3 1.6 0.079 13.5 1.6 2.0 1 0 0 1 1 1 0 Proline rich region of Caskin proteins RskA PF10099.9 OAG19930.1 - 1.7 8.9 10.1 0.13 12.5 0.8 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA STE3 PF02076.15 OAG19931.1 - 1.4e-74 250.9 28.1 2e-74 250.4 28.1 1.2 1 0 0 1 1 1 1 Pheromone A receptor Pkinase PF00069.25 OAG19931.1 - 6.8e-59 199.4 0.0 1.2e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19931.1 - 3.6e-26 92.0 0.0 1.4e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 OAG19931.1 - 0.00021 21.6 0.0 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 FHA domain Pkinase_fungal PF17667.1 OAG19931.1 - 0.00032 19.6 0.0 0.00056 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG19931.1 - 0.0047 16.3 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG19931.1 - 0.0048 15.9 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 OAG19931.1 - 0.04 13.5 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 OAG19931.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UQ_con PF00179.26 OAG19932.1 - 2.1e-39 134.4 0.0 2.4e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG19932.1 - 0.015 15.6 0.1 0.02 15.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 OAG19932.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B ADH_N PF08240.12 OAG19933.1 - 3e-27 94.6 5.2 6.3e-27 93.6 5.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG19933.1 - 1.9e-18 66.7 0.2 3.2e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG19933.1 - 0.0001 21.9 0.2 0.00016 21.2 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG19933.1 - 0.0003 21.8 0.1 0.0005 21.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG19933.1 - 0.00065 19.1 0.7 0.0012 18.1 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG19933.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG19933.1 - 0.47 9.7 1.8 0.74 9.0 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain HET PF06985.11 OAG19934.1 - 2e-32 112.6 0.0 3.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) P5-ATPase PF12409.8 OAG19935.1 - 1.8e-39 134.7 0.0 4.3e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 OAG19935.1 - 1.4e-31 109.4 1.0 3e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG19935.1 - 5.4e-16 59.5 0.1 1.9e-09 38.1 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OAG19935.1 - 6.5e-05 22.7 7.8 6.5e-05 22.7 7.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAG19935.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG19935.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG19935.1 - 0.18 11.5 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UFD1 PF03152.14 OAG19939.1 - 1.1e-71 239.8 0.0 1.4e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.16 OAG19940.1 - 2.1e-10 40.1 0.1 4.3e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 GYF domain R3H PF01424.22 OAG19941.1 - 2.6e-11 43.3 0.0 5.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAG19941.1 - 4.8e-06 26.3 0.1 1.2e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.17 OAG19942.1 - 6.9e-28 97.1 1.1 1.4e-27 96.1 1.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 OAG19942.1 - 0.04 14.4 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Ets-domain DUF1828 PF08861.10 OAG19942.1 - 0.098 12.9 0.2 43 4.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Seryl_tRNA_N PF02403.22 OAG19942.1 - 2.8 8.2 7.1 1.3 9.3 0.4 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Chitin_bind_1 PF00187.19 OAG19943.1 - 1.1e-10 41.8 36.4 3.6e-09 36.9 21.1 2.3 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_43 PF04616.14 OAG19946.1 - 4.3e-68 229.7 2.5 6.5e-68 229.1 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG19946.1 - 5.8e-20 71.9 0.0 9.3e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Reg_prop PF07494.11 OAG19946.1 - 0.15 12.4 0.7 6.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller GluR_Homer-bdg PF10606.9 OAG19947.1 - 0.27 11.5 2.3 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Pkinase PF00069.25 OAG19949.1 - 3.7e-50 170.7 0.0 5.3e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19949.1 - 1.8e-29 102.8 0.0 3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG19949.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG19949.1 - 0.0093 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG19949.1 - 0.034 14.1 0.3 1 9.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sad1_UNC PF07738.13 OAG19950.1 - 9.6e-31 106.5 0.0 1.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal VCBS PF13517.6 OAG19951.1 - 4e-14 52.9 0.1 2.1e-06 28.2 0.0 4.1 4 1 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HET PF06985.11 OAG19951.1 - 1.6e-11 44.8 7.0 1e-08 35.7 1.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TcdB_toxin_midN PF12256.8 OAG19951.1 - 0.0024 17.3 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 OAG19951.1 - 0.0034 17.5 0.0 0.18 12.0 0.0 2.9 3 0 0 3 3 3 1 FG-GAP repeat CorA PF01544.18 OAG19952.1 - 2e-06 27.3 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MMR_HSR1 PF01926.23 OAG19953.1 - 1.7e-17 63.5 0.6 5e-15 55.6 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG19953.1 - 1.6e-07 31.0 0.1 5.4e-06 26.0 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG19953.1 - 3.1e-06 27.2 0.3 0.0024 17.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OAG19953.1 - 0.00043 20.4 4.3 0.17 12.0 0.4 3.7 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 OAG19953.1 - 0.0045 16.3 0.6 0.0089 15.4 0.1 1.7 2 0 0 2 2 2 1 AIG1 family LTV PF04180.14 OAG19954.1 - 6.2e-123 411.3 21.2 7.1e-123 411.1 21.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein His_Phos_2 PF00328.22 OAG19955.1 - 1.8e-12 47.3 0.4 3.1e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PIG-P PF08510.12 OAG19956.1 - 4.2e-52 175.2 2.0 6.4e-52 174.6 2.0 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 OAG19956.1 - 0.2 12.0 7.3 0.35 11.2 7.3 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ank_2 PF12796.7 OAG19959.1 - 4.9e-27 94.3 0.1 5.8e-07 30.0 0.0 4.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG19959.1 - 1.9e-21 76.1 1.0 1.3e-05 25.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG19959.1 - 1.4e-18 65.0 0.6 0.059 14.0 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OAG19959.1 - 9.3e-12 45.0 0.5 0.27 11.6 0.0 6.3 4 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG19959.1 - 2.2e-11 43.7 7.2 0.05 14.1 0.0 7.1 6 1 1 7 7 7 3 Ankyrin repeat Acyl-CoA_dh_1 PF00441.24 OAG19960.1 - 1e-27 97.2 0.2 1.8e-27 96.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG19960.1 - 5.2e-21 74.6 0.0 9.1e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG19960.1 - 6e-17 62.3 0.1 2.5e-16 60.3 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG19960.1 - 1.8e-10 41.2 0.2 3.4e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PK_C PF02887.16 OAG19962.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Pkinase PF00069.25 OAG19963.1 - 5.5e-66 222.6 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19963.1 - 2.3e-24 86.1 0.0 3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG19963.1 - 3.6e-06 26.5 0.0 1.7e-05 24.3 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OAG19963.1 - 0.0021 18.0 0.1 0.0086 16.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG19963.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAG19963.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 OAG19964.1 - 4.2e-79 264.8 0.8 7.4e-79 264.0 0.8 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 OAG19964.1 - 1.7e-70 237.5 1.0 2.6e-70 236.9 1.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 OAG19964.1 - 1 9.0 3.3 0.66 9.6 0.1 2.3 3 0 0 3 3 3 0 MIF4G domain Mg_trans_NIPA PF05653.14 OAG19966.1 - 3e-58 197.3 1.2 3.9e-58 196.9 1.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG19966.1 - 0.0016 18.6 0.7 0.0016 18.6 0.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family CPP1-like PF11833.8 OAG19966.1 - 0.19 11.3 4.8 0.52 9.9 4.8 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WSC PF01822.19 OAG19969.1 - 6.3e-16 58.3 10.3 6.3e-16 58.3 10.3 3.4 3 1 0 3 3 3 1 WSC domain LRRFIP PF09738.9 OAG19969.1 - 0.00057 19.5 1.0 0.00073 19.1 1.0 1.2 1 0 0 1 1 1 1 LRRFIP family Golgin_A5 PF09787.9 OAG19969.1 - 0.015 14.8 7.1 0.019 14.4 7.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HMMR_N PF15905.5 OAG19969.1 - 0.016 14.7 5.2 0.021 14.3 5.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Bse634I PF07832.11 OAG19969.1 - 0.023 14.1 0.3 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease TMPIT PF07851.13 OAG19969.1 - 0.61 9.3 3.5 0.94 8.7 3.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 OAG19969.1 - 0.81 10.0 8.2 1.2 9.4 8.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cdh1_DBD_1 PF18196.1 OAG19969.1 - 1.2 9.4 4.0 1.9 8.8 4.0 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4407 PF14362.6 OAG19969.1 - 1.9 7.8 6.9 2.7 7.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HET PF06985.11 OAG19970.1 - 4.9e-26 91.8 0.2 4.9e-26 91.8 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AlcCBM31 PF11606.8 OAG19970.1 - 0.081 13.1 0.0 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 Family 31 carbohydrate binding protein Swi5 PF07061.11 OAG19972.1 - 2.5e-24 85.1 0.3 5.8e-24 84.0 0.3 1.7 1 0 0 1 1 1 1 Swi5 Ytp1 PF10355.9 OAG19973.1 - 2.2e-72 243.6 19.0 2.2e-72 243.6 19.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG19973.1 - 2.5e-31 107.6 0.4 2.5e-31 107.6 0.4 2.9 4 1 1 5 5 5 1 Domain of unknown function (DUF2427) Tetraspanin PF00335.20 OAG19973.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.8 2 1 0 2 2 2 0 Tetraspanin family Helo_like_N PF17111.5 OAG19974.1 - 4.1e-06 26.3 0.3 4.1e-06 26.3 0.3 2.7 2 1 1 3 3 3 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 OAG19974.1 - 0.22 12.0 4.9 6.5 7.3 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAG19974.1 - 0.71 9.9 5.6 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OAG19974.1 - 0.75 9.8 5.0 1.6 8.7 0.4 2.7 3 0 0 3 3 3 0 Laminin Domain II DUF948 PF06103.11 OAG19974.1 - 6.9 7.0 6.4 7.6 6.9 0.6 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.12 OAG19974.1 - 7.9 6.5 9.5 13 5.8 4.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sybindin PF04099.12 OAG19976.1 - 1.8e-25 89.5 0.0 2.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAG19976.1 - 0.033 14.3 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 OAG19977.1 - 3.9e-63 213.3 0.1 2.2e-56 191.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19977.1 - 6.2e-39 133.8 0.3 5.1e-37 127.6 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG19977.1 - 8.9e-08 31.8 0.0 4.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAG19977.1 - 2.2e-05 23.4 0.1 2.2e-05 23.4 0.1 2.8 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAG19977.1 - 0.0024 17.8 0.3 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG19977.1 - 0.15 11.6 0.3 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 OAG19979.1 - 7.9e-25 87.5 0.1 2.4e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG19979.1 - 5.9e-15 55.5 0.0 1.1e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG19979.1 - 8.5e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAG19979.1 - 0.0007 19.7 0.3 0.0019 18.3 0.1 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG19979.1 - 0.012 16.2 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG19979.1 - 0.034 13.5 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SMI1_KNR4 PF09346.10 OAG19980.1 - 2.6e-07 31.1 0.0 6.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 OAG19980.1 - 1.1e-06 29.1 0.0 3.7e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 OAG19980.1 - 5.7e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall DEK_C PF08766.11 OAG19980.1 - 0.022 14.7 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 DEK C terminal domain DUF5075 PF16825.5 OAG19980.1 - 0.084 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 IGP family C-type lectin domain LIN37 PF15306.6 OAG19981.1 - 0.012 15.9 0.8 0.015 15.6 0.8 1.0 1 0 0 1 1 1 0 LIN37 ADH_zinc_N PF00107.26 OAG19981.1 - 0.061 13.3 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SKG6 PF08693.10 OAG19982.1 - 0.00044 19.6 0.5 0.00088 18.6 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.10 OAG19983.1 - 0.0013 18.1 0.8 0.0013 18.1 0.8 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OAG19983.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FeoB_C PF07664.12 OAG19983.1 - 0.078 12.7 0.2 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus VSP PF03302.13 OAG19983.1 - 0.1 11.4 3.3 0.27 10.0 0.1 2.3 2 1 1 3 3 3 0 Giardia variant-specific surface protein C4 PF01413.19 OAG19983.1 - 0.14 12.5 0.2 12 6.3 0.0 2.5 2 1 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen CMAS PF02353.20 OAG19984.1 - 4.3e-36 124.6 0.1 6e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OAG19984.1 - 1e-15 57.9 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG19984.1 - 5.4e-15 55.8 0.0 9.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG19984.1 - 8.8e-15 55.2 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG19984.1 - 5.6e-13 49.1 0.0 7.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG19984.1 - 1.7e-10 41.5 0.0 2.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG19984.1 - 1.5e-08 34.3 0.0 3.7e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 OAG19984.1 - 1.4e-05 24.6 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 OAG19984.1 - 1.6e-05 24.5 0.0 4.9e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAG19984.1 - 7.8e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAG19984.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 OAG19984.1 - 0.0042 16.9 0.0 0.0098 15.7 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAG19984.1 - 0.0053 16.9 0.0 0.074 13.1 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 OAG19984.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 OAG19984.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 OAG19984.1 - 0.04 13.6 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FTO_CTD PF12934.7 OAG19984.1 - 0.11 12.2 0.9 0.22 11.2 0.9 1.4 1 0 0 1 1 1 0 FTO C-terminal domain Methyltransf_32 PF13679.6 OAG19984.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 OAG19984.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GidB PF02527.15 OAG19984.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NADH_B2 PF14813.6 OAG19985.1 - 0.046 13.5 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 OAG19986.1 - 2.5e-64 217.2 0.0 3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG19986.1 - 1.2e-28 100.1 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG19986.1 - 0.00096 18.5 0.0 0.0072 15.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAG19986.1 - 0.0015 18.0 0.4 0.0023 17.3 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG19986.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAG19986.1 - 0.082 11.8 0.1 0.15 10.9 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain HET PF06985.11 OAG19987.1 - 1.4e-19 70.9 0.0 2.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dala_Dala_lig_C PF07478.13 OAG19988.1 - 2.4e-12 46.8 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 OAG19988.1 - 5e-05 23.0 0.1 0.00022 20.8 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAG19988.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OAG19988.1 - 0.00028 20.4 0.0 0.00061 19.4 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 OAG19988.1 - 0.00048 20.2 0.0 0.00088 19.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG19988.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Cupin_2 PF07883.11 OAG19989.1 - 5e-09 35.8 0.2 0.0011 18.6 0.0 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG19989.1 - 0.011 15.4 0.1 0.37 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAG19989.1 - 0.019 14.6 0.1 0.94 9.1 0.0 2.2 2 0 0 2 2 2 0 Cupin ORC6 PF05460.13 OAG19990.1 - 0.0014 18.0 1.3 0.0015 17.9 1.3 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.19 OAG19990.1 - 0.045 14.3 0.1 0.045 14.3 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein CNDH2_M PF16869.5 OAG19990.1 - 0.18 12.5 5.3 0.37 11.5 5.3 1.6 1 1 0 1 1 1 0 PF16858 Pox_A12 PF04651.13 OAG19990.1 - 0.2 11.7 3.2 0.78 9.8 3.3 1.8 1 1 0 1 1 1 0 Poxvirus A12 protein OSTbeta PF15048.6 OAG19991.1 - 0.033 14.3 0.2 0.081 13.1 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein GCR1_C PF12550.8 OAG19991.1 - 0.037 14.3 1.3 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes P21-Arc PF04062.14 OAG19992.1 - 6.6e-73 244.4 0.0 7.5e-73 244.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.11 OAG19993.1 - 9e-17 61.3 0.1 3e-16 59.6 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAG19993.1 - 1e-16 61.6 0.0 1.9e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAG19993.1 - 3.9e-12 46.3 0.0 2.6e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG19993.1 - 2.7e-10 40.5 0.0 5.4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OAG19993.1 - 9.3e-07 29.1 0.0 3.3e-06 27.3 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 OAG19993.1 - 2e-06 27.8 0.2 8.9e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAG19993.1 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG19993.1 - 2.7e-06 27.4 0.3 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG19993.1 - 2.7e-06 27.9 0.0 1.3e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 OAG19993.1 - 4.7e-06 26.5 0.1 8.6e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 OAG19993.1 - 7.6e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG19993.1 - 9.1e-06 26.0 0.0 3.4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG19993.1 - 1.7e-05 24.1 0.0 3.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG19993.1 - 5.7e-05 22.9 0.1 0.00026 20.8 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 OAG19993.1 - 0.00011 22.1 0.1 0.0004 20.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG19993.1 - 0.00036 20.3 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 OAG19993.1 - 0.00042 19.8 0.1 0.015 14.7 0.1 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAG19993.1 - 0.0005 20.4 0.1 0.0018 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG19993.1 - 0.00059 19.9 0.0 0.057 13.4 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG19993.1 - 0.00089 18.8 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 OAG19993.1 - 0.00089 19.3 0.0 0.0025 17.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 OAG19993.1 - 0.0071 16.1 0.1 0.045 13.5 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 OAG19993.1 - 0.011 16.2 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG19993.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 OAG19993.1 - 0.013 14.9 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 OAG19993.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG19993.1 - 0.021 14.4 0.0 0.051 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG19993.1 - 0.026 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAG19993.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG19993.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OAG19993.1 - 0.1 12.3 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 OAG19993.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 OAG19993.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter p450 PF00067.22 OAG19996.1 - 1.2e-73 248.4 0.0 1.4e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 OAG19997.1 - 2.8e-82 277.2 0.0 3.4e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG19997.1 - 2.1e-07 31.0 0.1 1.1e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FTZ PF03867.14 OAG19997.1 - 0.11 12.0 1.4 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Helicase_C PF00271.31 OAG19998.1 - 0.0032 17.8 0.0 0.038 14.3 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OAG19998.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 OAG19999.1 - 7.7e-58 195.9 0.7 4.7e-45 153.8 0.1 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Prok-RING_4 PF14447.6 OAG19999.1 - 0.0015 18.4 4.6 0.0037 17.1 4.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG19999.1 - 0.0021 18.0 7.1 0.0048 16.8 7.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 OAG19999.1 - 0.0023 17.7 0.0 0.026 14.3 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 OAG19999.1 - 0.0085 16.4 7.9 0.02 15.2 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 OAG19999.1 - 0.0086 16.1 0.0 0.26 11.3 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAG19999.1 - 0.037 13.9 7.7 0.098 12.5 7.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG19999.1 - 0.092 12.8 7.2 0.26 11.3 7.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAG19999.1 - 0.098 12.8 6.7 0.14 12.4 4.3 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 OAG19999.1 - 0.11 12.2 3.1 0.31 10.8 3.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SWI2_SNF2 PF18766.1 OAG19999.1 - 0.12 12.1 0.0 0.86 9.2 0.0 2.2 2 1 0 2 2 2 0 SWI2/SNF2 ATPase zf-C3HC4_2 PF13923.6 OAG19999.1 - 0.15 11.9 10.0 0.095 12.6 7.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 OAG19999.1 - 0.4 10.2 2.4 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 OAG19999.1 - 4.3 7.5 5.2 15 5.7 5.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon NACHT PF05729.12 OAG20000.1 - 1.2e-09 38.3 0.0 2.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.26 OAG20000.1 - 1.4e-09 37.9 23.5 0.0002 21.6 1.1 5.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG20000.1 - 3.1e-07 30.2 5.6 0.00027 20.9 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG20000.1 - 3.4e-05 24.3 20.3 0.017 15.9 0.6 5.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG20000.1 - 4.7e-05 23.6 3.0 4.7e-05 23.6 3.0 5.7 5 1 0 5 5 5 2 Zinc-finger double domain KAP_NTPase PF07693.14 OAG20000.1 - 0.0014 17.9 0.2 0.031 13.5 0.2 2.4 1 1 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 OAG20000.1 - 0.003 18.0 0.0 0.0092 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG20000.1 - 0.012 16.1 0.0 0.079 13.4 0.0 2.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_3rep PF18868.1 OAG20000.1 - 0.014 16.1 4.4 0.017 15.8 2.7 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 OAG20000.1 - 0.027 14.8 12.7 2 8.8 2.0 5.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.6 OAG20000.1 - 0.089 13.1 0.0 0.46 10.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain XPA_N PF01286.18 OAG20000.1 - 1.2 9.2 6.2 8.1 6.6 0.6 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-met PF12874.7 OAG20000.1 - 6.1 7.4 9.2 4.3 7.9 1.9 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Peroxidase_2 PF01328.17 OAG20001.1 - 1.3e-49 169.2 0.0 1.8e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PAN_1 PF00024.26 OAG20002.1 - 3.9e-09 36.3 3.3 0.0056 16.6 1.2 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 OAG20002.1 - 0.0059 16.5 16.0 0.044 13.7 0.9 3.7 3 1 0 3 3 3 3 PAN domain PTP_tm PF18861.1 OAG20002.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2207 PF09972.9 OAG20002.1 - 0.25 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CFEM PF05730.11 OAG20003.1 - 0.0015 18.6 1.5 0.003 17.6 1.5 1.5 1 0 0 1 1 1 1 CFEM domain DUF4662 PF15578.6 OAG20005.1 - 0.0051 16.6 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4662) Lactonase PF10282.9 OAG20006.1 - 2.9e-63 214.2 0.0 3.8e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller VID27 PF08553.10 OAG20006.1 - 0.011 14.9 0.0 0.078 12.0 0.0 2.0 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 OAG20006.1 - 0.082 12.9 0.2 0.31 11.0 0.0 2.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat F5_F8_type_C PF00754.25 OAG20006.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain ANAPC4_WD40 PF12894.7 OAG20006.1 - 0.14 12.5 0.0 2.7 8.4 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_4 PF01565.23 OAG20007.1 - 1.8e-19 69.9 0.2 4.3e-19 68.6 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG20007.1 - 2.6e-11 43.5 0.0 5.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3040 PF11239.8 OAG20008.1 - 0.39 11.0 5.6 2.2 8.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 OAG20008.1 - 0.65 10.1 4.1 0.56 10.3 0.3 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Esterase_phd PF10503.9 OAG20009.1 - 2.6e-07 30.4 0.0 6.2e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG20009.1 - 0.00064 19.3 0.0 0.0025 17.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG20009.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 OAG20009.1 - 0.047 12.4 0.0 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.16 OAG20010.1 - 2.3e-38 132.0 55.8 1e-32 113.4 26.1 2.8 2 2 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG20010.1 - 5.5e-07 28.4 22.5 7.3e-07 28.0 22.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.28 OAG20011.1 - 1.4e-12 47.8 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAG20011.1 - 0.00037 20.2 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GDA1_CD39 PF01150.17 OAG20012.1 - 9.9e-111 370.4 0.0 1.3e-110 370.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Sec7 PF01369.20 OAG20013.1 - 1.9e-67 226.5 0.1 3e-67 225.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAG20013.1 - 5.7e-18 65.3 0.1 5e-17 62.3 0.0 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SPEG_u2 PF16650.5 OAG20013.1 - 0.015 15.5 0.1 0.057 13.6 0.1 2.0 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Anp1 PF03452.14 OAG20014.1 - 2.7e-113 377.8 0.5 4.7e-113 377.0 0.0 1.6 2 0 0 2 2 2 1 Anp1 TssC PF17541.2 OAG20014.1 - 0.052 12.4 5.5 0.079 11.8 5.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Hid1 PF12722.7 OAG20014.1 - 5.4 5.0 7.4 7.1 4.6 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNase_PH PF01138.21 OAG20015.1 - 4.1e-24 85.6 0.0 7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Drf_FH1 PF06346.12 OAG20015.1 - 0.062 13.0 3.3 0.1 12.3 3.3 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 GP46 PF07409.12 OAG20015.1 - 0.29 10.9 0.8 0.7 9.7 0.6 1.6 2 0 0 2 2 2 0 Phage protein GP46 Glyco_hydro_72 PF03198.14 OAG20016.1 - 1.4e-119 399.0 3.7 1.8e-119 398.7 3.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase TAP42 PF04177.12 OAG20016.1 - 0.21 10.7 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 TAP42-like family Ribonuclease_3 PF00636.26 OAG20017.1 - 1.8e-36 124.9 0.0 1e-17 64.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OAG20017.1 - 7.6e-26 90.1 0.1 4.6e-25 87.6 0.1 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OAG20017.1 - 1.2e-18 67.5 0.0 7.1e-10 39.1 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 OAG20017.1 - 1.5e-17 63.9 0.1 5.3e-17 62.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG20017.1 - 4.3e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG20017.1 - 4.4e-08 33.1 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SDA1 PF05285.12 OAG20017.1 - 3.4 7.0 12.7 6.6 6.1 12.7 1.4 1 0 0 1 1 1 0 SDA1 TAP42 PF04177.12 OAG20018.1 - 2.4e-110 368.6 3.2 2.7e-110 368.4 3.2 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4011 PF13195.6 OAG20018.1 - 0.0056 16.6 1.0 0.0091 15.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) Lipase_GDSL_2 PF13472.6 OAG20019.1 - 2.6e-11 44.2 0.0 1.2e-09 38.8 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG20019.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Myb_DNA-bind_2 PF08914.11 OAG20019.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Neisseria_TspB PF05616.13 OAG20020.1 - 0.013 14.1 6.4 0.014 13.9 6.4 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Zip PF02535.22 OAG20020.1 - 0.55 9.4 2.8 0.6 9.3 2.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_71 PF03659.14 OAG20021.1 - 3.6e-88 295.9 2.7 4.5e-88 295.6 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Hamartin PF04388.12 OAG20022.1 - 2.7e-23 82.6 34.9 3.4e-22 79.0 34.6 2.7 1 1 0 1 1 1 1 Hamartin protein GIT_CC PF16559.5 OAG20022.1 - 0.0039 17.0 1.6 0.0039 17.0 1.6 3.9 3 1 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 OAG20022.1 - 0.0059 16.9 5.7 0.0059 16.9 5.7 3.9 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 NOA36 PF06524.12 OAG20022.1 - 1.5 8.1 5.7 2.9 7.1 5.7 1.4 1 0 0 1 1 1 0 NOA36 protein tRNA_lig_CPD PF08302.11 OAG20024.1 - 0.06 12.8 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DUF3237 PF11578.8 OAG20025.1 - 4.8e-43 146.6 0.4 5.5e-43 146.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Rrn6 PF10214.9 OAG20026.1 - 2.1e-205 684.9 0.8 2.6e-205 684.6 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Cwf_Cwc_15 PF04889.12 OAG20026.1 - 0.36 10.5 7.9 0.64 9.7 7.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spindle_Spc25 PF08234.12 OAG20027.1 - 8.9e-28 96.3 0.4 3.2e-27 94.5 0.2 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 HEPN_AbiU2 PF18734.1 OAG20027.1 - 0.0027 17.3 0.7 0.0056 16.2 0.7 1.5 1 0 0 1 1 1 1 AbiU2 Atg14 PF10186.9 OAG20027.1 - 0.041 13.0 7.5 0.059 12.5 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HA2 PF04408.23 OAG20028.1 - 7.8e-18 64.7 0.2 1.6e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG20028.1 - 7e-14 51.9 0.0 1.8e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG20028.1 - 2.1e-11 44.2 0.0 4.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG20028.1 - 6e-06 26.1 0.1 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG20028.1 - 1.8e-05 25.0 0.1 5e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG20028.1 - 0.00072 19.9 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG20028.1 - 0.0036 17.0 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG20028.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 OAG20028.1 - 0.017 14.7 0.3 0.24 11.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OAG20028.1 - 0.045 14.2 0.1 0.43 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 OAG20028.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein PAXNEB PF05625.11 OAG20029.1 - 1.4e-115 386.5 0.0 1.6e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein CBP_BcsO PF17037.5 OAG20029.1 - 5.9 7.0 7.1 3.2 7.9 0.5 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO EF-hand_7 PF13499.6 OAG20031.1 - 2.9e-07 30.8 0.1 6.2e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OAG20031.1 - 4.6e-07 29.2 0.3 0.0091 15.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAG20031.1 - 5.9e-05 22.3 0.1 0.00023 20.5 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAG20031.1 - 0.00041 20.1 0.3 0.0013 18.6 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG20031.1 - 0.0011 18.3 0.1 0.003 17.0 0.1 1.6 1 0 0 1 1 1 1 EF hand DUF4891 PF16232.5 OAG20031.1 - 0.081 13.5 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4891) DLH PF01738.18 OAG20032.1 - 2.5e-16 59.9 0.0 4.9e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family WD40 PF00400.32 OAG20033.1 - 2.3e-13 50.4 2.3 0.17 12.8 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG20033.1 - 0.011 16.0 0.0 2.7 8.4 0.0 3.8 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_1 PF03029.17 OAG20034.1 - 3.9e-76 256.0 0.0 2.2e-75 253.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 OAG20034.1 - 0.003 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.12 OAG20034.1 - 0.0053 16.5 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG20034.1 - 0.011 16.3 0.1 0.22 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 OAG20034.1 - 0.012 15.6 0.0 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG20034.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 OAG20034.1 - 0.043 14.2 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OAG20034.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OAG20034.1 - 0.058 13.8 0.0 0.11 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 OAG20034.1 - 0.061 12.8 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAG20034.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG20034.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG20034.1 - 0.13 11.9 0.0 2.3 7.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 OAG20034.1 - 0.23 10.9 0.2 1.8 7.9 0.2 2.1 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Snf7 PF03357.21 OAG20035.1 - 1.3e-17 63.9 15.9 1.3e-17 63.9 15.9 2.3 2 1 1 3 3 3 1 Snf7 DUF2408 PF10303.9 OAG20035.1 - 3.4 8.3 10.5 5.9 7.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) SKIP_SNW PF02731.15 OAG20035.1 - 8.6 6.0 17.6 0.25 11.0 3.0 2.6 2 0 0 2 2 2 0 SKIP/SNW domain ESSS PF10183.9 OAG20036.1 - 2.5e-17 63.0 0.0 2.8e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COX7C PF02935.16 OAG20036.1 - 1 9.7 3.6 0.59 10.4 0.5 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Glyco_hydro_7 PF00840.20 OAG20037.1 - 5.1e-202 671.3 17.6 5.8e-202 671.2 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Kei1 PF08552.11 OAG20040.1 - 8.2e-59 198.7 2.3 1.1e-58 198.3 2.3 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 adh_short_C2 PF13561.6 OAG20041.1 - 2.3e-31 109.2 0.0 2.9e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20041.1 - 1.8e-21 76.5 0.0 3.2e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20041.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 OAG20041.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NolB PF17398.2 OAG20041.1 - 0.096 13.1 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein NolB SUV3_C PF12513.8 OAG20042.1 - 1.2e-18 66.7 0.4 3.2e-18 65.4 0.4 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 OAG20042.1 - 3.4e-13 49.2 0.4 7.6e-13 48.1 0.4 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 OAG20042.1 - 1.8e-10 41.1 0.0 4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.23 OAG20043.1 - 1.6e-120 404.0 0.0 2.3e-120 403.6 0.0 1.2 1 0 0 1 1 1 1 Sec1 family partial_CstF PF15861.5 OAG20043.1 - 0.24 11.2 1.6 0.53 10.1 1.6 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DIM1 PF02966.16 OAG20044.1 - 7.4e-62 207.0 0.0 8.4e-62 206.8 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAG20044.1 - 0.00016 21.6 0.1 0.00021 21.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG20044.1 - 0.15 12.4 1.1 0.26 11.7 1.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF4674 PF15719.5 OAG20045.1 - 0.15 12.0 2.1 0.2 11.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) DUF3665 PF12427.8 OAG20045.1 - 0.29 10.9 2.1 3.9 7.3 2.1 2.3 1 1 0 1 1 1 0 Branched-chain amino acid aminotransferase F-box PF00646.33 OAG20046.1 - 1.7e-08 34.1 0.0 4.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG20046.1 - 2.2e-08 33.9 0.3 9.8e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like Ribosom_S12_S23 PF00164.25 OAG20047.1 - 2.7e-31 107.5 0.9 3.8e-31 107.0 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 OAG20047.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S12 Metallophos PF00149.28 OAG20048.1 - 3.6e-38 132.1 0.5 5.9e-38 131.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG20048.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Peptidase_C48 PF02902.19 OAG20049.1 - 6.9e-18 65.3 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ADH_zinc_N PF00107.26 OAG20050.1 - 4.7e-28 97.7 0.7 8.2e-28 97.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20050.1 - 1.7e-14 55.0 0.0 3.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG20050.1 - 2.1e-11 43.7 0.0 8.6e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG20050.1 - 0.00042 20.6 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain PALP PF00291.25 OAG20050.1 - 0.018 14.4 1.1 0.029 13.8 1.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CMAS PF02353.20 OAG20050.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PAP2 PF01569.21 OAG20052.1 - 2.6e-18 66.1 4.5 2.6e-18 66.1 4.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAG20052.1 - 5.8e-06 26.1 0.7 2.4e-05 24.1 0.7 2.1 1 0 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 OAG20053.1 - 2.4e-49 167.1 0.0 3.4e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG20053.1 - 9.3e-20 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG20053.1 - 7.8e-06 25.5 0.0 1.7e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 OAG20053.1 - 0.041 13.6 0.6 4.5 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG20053.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 OAG20054.1 - 4.7e-25 87.5 1.5 5.7e-25 87.3 1.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 OAG20054.1 - 0.0012 18.8 0.8 0.0017 18.3 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 WVELL PF14043.6 OAG20054.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 WVELL protein tRNA_int_endo PF01974.17 OAG20055.1 - 2.5e-11 43.5 0.0 5.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pex14_N PF04695.13 OAG20055.1 - 2.2 8.9 8.9 12 6.6 0.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Wyosine_form PF08608.12 OAG20056.1 - 9.3e-23 80.4 0.0 2.9e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 OAG20056.1 - 8.6e-19 68.5 0.0 2.5e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 OAG20056.1 - 3.6e-10 40.2 0.1 6.3e-09 36.2 0.1 2.5 1 1 0 1 1 1 1 Flavodoxin IML1 PF12257.8 OAG20057.1 - 5.4e-118 393.2 0.0 7.5e-118 392.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAG20057.1 - 5.5e-26 90.4 0.4 1.1e-25 89.4 0.4 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NAD_binding_10 PF13460.6 OAG20058.1 - 1.9e-19 70.3 2.0 7.8e-19 68.3 0.2 2.4 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG20058.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG20058.1 - 0.051 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG20058.1 - 0.057 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cation_ATPase_C PF00689.21 OAG20059.1 - 5.5e-48 163.1 8.7 5.5e-48 163.1 8.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG20059.1 - 1.5e-38 132.1 0.6 1.5e-38 132.1 0.6 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAG20059.1 - 1.2e-18 67.0 0.0 2.8e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG20059.1 - 1.3e-18 68.1 1.6 8.2e-18 65.5 1.6 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG20059.1 - 5.3e-07 29.6 0.1 4.9e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG20059.1 - 2.2e-06 27.3 0.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Phage_holin_3_6 PF07332.11 OAG20059.1 - 2.1 8.4 9.5 1.9 8.6 1.2 3.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Cu_bind_like PF02298.17 OAG20060.1 - 0.021 14.8 0.2 0.046 13.7 0.2 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain NAD_binding_2 PF03446.15 OAG20061.1 - 1.5e-39 135.7 0.2 2.1e-39 135.2 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG20061.1 - 3.1e-27 95.3 0.0 4.9e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAG20061.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAG20061.1 - 0.00037 21.0 0.0 0.00094 19.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAG20061.1 - 0.0046 17.8 0.0 0.0098 16.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 OAG20061.1 - 0.0078 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG20061.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PTRF_SDPR PF15237.6 OAG20062.1 - 0.043 13.4 0.2 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 PTRF/SDPR family 5_3_exonuc_N PF02739.16 OAG20062.1 - 0.25 11.2 3.6 2.4 8.0 2.3 3.1 3 1 0 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain DSPc PF00782.20 OAG20063.1 - 8.6e-27 93.6 0.0 2.7e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG20063.1 - 0.0005 19.7 0.0 0.004 16.8 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG20063.1 - 0.1 12.7 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate DNA_pol_delta_4 PF04081.13 OAG20064.1 - 6.8e-15 55.6 1.5 1.1e-14 54.9 1.5 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 RXT2_N PF08595.11 OAG20064.1 - 0.025 14.6 1.8 0.033 14.2 1.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC14 PF08045.11 OAG20064.1 - 0.7 9.0 3.4 1.9 7.6 0.1 2.0 1 1 1 2 2 2 0 Cell division control protein 14, SIN component DcpS PF05652.12 OAG20065.1 - 6.1e-35 120.2 0.0 1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 OAG20065.1 - 1.5e-30 106.0 0.0 2.5e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_C12 PF01088.21 OAG20066.1 - 6.6e-56 189.4 0.0 7.9e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 tRNA_bind PF01588.20 OAG20067.1 - 2.3e-21 75.7 0.1 6.6e-21 74.2 0.1 1.8 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 OAG20067.1 - 0.00026 20.9 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG20067.1 - 0.003 17.7 1.0 0.036 14.3 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Sad1_UNC PF07738.13 OAG20068.1 - 2.4e-21 76.1 0.0 1.8e-20 73.3 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal RuvX PF03652.15 OAG20068.1 - 0.12 12.8 1.7 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Epimerase PF01370.21 OAG20070.1 - 4.8e-45 153.9 0.0 6.3e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG20070.1 - 8.4e-45 153.6 0.0 2.4e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG20070.1 - 9.9e-17 60.8 0.0 5.2e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG20070.1 - 1.2e-12 47.5 0.0 1.3e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG20070.1 - 4e-12 45.8 0.0 6.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OAG20070.1 - 3.5e-09 36.4 0.1 5.8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20070.1 - 5.8e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG20070.1 - 0.00036 20.1 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG20070.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG20070.1 - 0.0082 15.3 0.1 0.69 9.0 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 OAG20070.1 - 0.036 13.6 0.0 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OAG20070.1 - 0.15 11.7 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCM PF00493.23 OAG20071.1 - 5.9e-103 342.8 0.3 9.5e-103 342.1 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG20071.1 - 4.2e-37 126.8 0.8 8.1e-37 125.9 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAG20071.1 - 1.7e-31 108.7 4.6 4.4e-31 107.3 4.6 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAG20071.1 - 1.9e-25 89.1 2.1 6.9e-25 87.3 0.3 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAG20071.1 - 5.4e-23 81.6 0.1 2.1e-22 79.6 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG20071.1 - 2e-08 33.9 0.1 8.4e-07 28.6 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAG20071.1 - 0.0011 18.7 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAG20071.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG20071.1 - 0.0091 16.0 0.0 0.028 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 OAG20071.1 - 0.73 10.0 6.0 1.8 8.7 6.0 1.6 1 0 0 1 1 1 0 GidA associated domain HA2 PF04408.23 OAG20072.1 - 5.6e-22 78.1 0.0 5.6e-22 78.1 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG20072.1 - 8.2e-21 74.2 0.0 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG20072.1 - 2.2e-13 50.5 0.0 6.5e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OAG20072.1 - 6.2e-10 39.3 0.8 1.4e-09 38.2 0.8 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 OAG20072.1 - 5.3e-05 23.5 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAG20072.1 - 0.00036 20.4 0.3 0.0011 18.8 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 OAG20072.1 - 0.00045 19.4 0.0 0.0014 17.7 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OAG20072.1 - 0.0041 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG20072.1 - 0.028 14.7 0.6 0.06 13.7 0.2 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OAG20072.1 - 0.029 14.4 0.1 0.32 11.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG20072.1 - 0.035 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 OAG20072.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Microtub_bd PF16796.5 OAG20072.1 - 0.078 12.9 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding RimM PF01782.18 OAG20072.1 - 0.12 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 RimM N-terminal domain AAA_16 PF13191.6 OAG20072.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Herpes_ori_bp PF02399.15 OAG20072.1 - 0.14 10.2 0.1 0.22 9.5 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein TauD PF02668.16 OAG20073.1 - 2.1e-55 188.4 0.4 2.9e-55 187.9 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_15 PF01793.16 OAG20074.1 - 6.2e-132 439.8 9.3 7.6e-132 439.5 9.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase FtsH_ext PF06480.15 OAG20074.1 - 0.23 11.8 1.3 18 5.8 0.0 2.8 3 0 0 3 3 3 0 FtsH Extracellular EGF_3 PF12947.7 OAG20074.1 - 0.24 11.6 2.4 0.45 10.8 2.4 1.4 1 0 0 1 1 1 0 EGF domain PAT1 PF09770.9 OAG20075.1 - 0 1156.1 18.2 0 1156.0 18.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Asp PF00026.23 OAG20076.1 - 7.3e-63 212.9 7.4 9.4e-63 212.5 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG20076.1 - 6.6e-07 29.7 3.2 0.0014 18.9 1.2 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG20076.1 - 4.5e-06 27.2 3.0 0.018 15.7 1.5 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 OAG20076.1 - 0.0096 15.7 0.2 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAG20076.1 - 0.038 14.6 2.3 7.9 7.1 0.6 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease UBA2_C PF16195.5 OAG20077.1 - 0.029 15.0 1.5 0.087 13.5 1.5 1.8 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF775 PF05603.12 OAG20078.1 - 2.2e-63 213.4 0.0 2.7e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) HD PF01966.22 OAG20079.1 - 3.6e-09 36.9 0.2 3.6e-09 36.9 0.2 1.6 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 OAG20079.1 - 0.11 11.9 0.2 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 HDOD domain Asparaginase PF00710.20 OAG20080.1 - 2e-49 167.7 1.7 2.9e-49 167.2 1.7 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG20080.1 - 4.7e-11 42.9 0.1 1.5e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Oxysterol_BP PF01237.18 OAG20081.1 - 6.3e-54 183.2 0.0 2.7e-51 174.6 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein TPR_2 PF07719.17 OAG20083.1 - 3.7e-11 42.2 15.5 0.00086 19.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG20083.1 - 5.2e-09 35.7 1.5 0.048 13.4 0.2 4.7 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.28 OAG20083.1 - 3.7e-07 29.7 9.1 0.036 13.9 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG20083.1 - 1.3e-06 28.9 13.6 0.023 15.4 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG20083.1 - 4.8e-06 26.9 13.4 2.5 9.2 0.1 6.7 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG20083.1 - 0.00022 21.2 5.9 0.49 10.7 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG20083.1 - 0.00023 21.6 12.5 0.027 15.0 0.2 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG20083.1 - 0.00025 21.3 0.5 0.00025 21.3 0.5 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG20083.1 - 0.00032 20.8 1.5 0.27 11.4 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG20083.1 - 0.0016 18.4 8.6 2 8.6 0.0 5.2 7 0 0 7 7 5 1 Tetratricopeptide repeat Trigger_C PF05698.14 OAG20083.1 - 0.011 15.7 0.2 0.026 14.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus TPR_20 PF14561.6 OAG20083.1 - 0.06 13.7 0.2 28 5.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 OAG20083.1 - 0.1 11.6 0.1 1.2 8.1 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase I-associated factor PAF67 Sel1 PF08238.12 OAG20083.1 - 0.14 12.9 1.3 4.9 8.0 0.0 3.4 4 0 0 4 4 3 0 Sel1 repeat TPR_4 PF07721.14 OAG20083.1 - 0.16 12.7 11.6 2.1 9.2 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG20083.1 - 3.9 7.5 9.2 3.9 7.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PNP_phzG_C PF10590.9 OAG20084.1 - 2.2e-21 75.6 2.4 3.2e-21 75.1 0.7 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAG20084.1 - 6.4e-19 67.9 0.0 9.1e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 OAG20084.1 - 0.0077 16.8 0.2 0.014 16.0 0.2 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SLAC1 PF03595.17 OAG20085.1 - 2.5e-73 247.2 47.0 2.8e-73 247.0 47.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel NIR_SIR PF01077.22 OAG20086.1 - 4.6e-55 185.5 0.0 2.9e-49 166.6 0.1 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAG20086.1 - 1.2e-31 108.4 0.0 4e-15 55.4 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAG20086.1 - 2.5e-27 95.9 0.0 5.9e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAG20086.1 - 6.9e-11 42.3 0.3 1.5e-10 41.2 0.3 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TraF PF13728.6 OAG20086.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein PAPS_reduct PF01507.19 OAG20087.1 - 8.7e-29 100.8 0.0 4e-26 92.1 0.0 2.4 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ADH_N_assoc PF13823.6 OAG20088.1 - 0.22 11.5 0.1 0.57 10.2 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Pec_lyase_C PF00544.19 OAG20089.1 - 1.3e-44 152.4 5.3 1.7e-44 151.9 5.3 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG20089.1 - 0.00012 22.0 9.4 0.0036 17.2 2.7 2.2 1 1 1 2 2 2 2 Right handed beta helix region Pkinase PF00069.25 OAG20091.1 - 1e-14 54.5 0.0 3.4e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20091.1 - 4.5e-09 36.0 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HET PF06985.11 OAG20092.1 - 3.4e-26 92.4 0.0 7.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG20092.1 - 7.1e-19 68.2 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20092.1 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 OAG20093.1 - 5.6e-21 75.4 0.1 8.1e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_10 PF13673.7 OAG20095.1 - 4.8e-09 36.2 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG20095.1 - 5.6e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG20095.1 - 1.2e-05 25.5 0.0 3e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG20095.1 - 0.03 14.3 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 OAG20095.1 - 0.044 13.9 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 OAG20096.1 - 1.2e-60 205.3 0.0 1.3e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 OAG20097.1 - 0.00047 20.2 11.8 0.0011 19.0 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAIN_A PF18619.1 OAG20097.1 - 0.0012 19.0 0.2 0.0034 17.5 0.2 1.8 1 0 0 1 1 1 1 GPCR-Autoproteolysis-INducing (GAIN) subdomain A BUD22 PF09073.10 OAG20097.1 - 0.048 13.0 0.4 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 BUD22 UPF0506 PF11703.8 OAG20097.1 - 3.2 8.2 8.8 9.3 6.7 0.8 2.6 1 1 1 2 2 2 0 UPF0506 MFS_1 PF07690.16 OAG20098.1 - 2.5e-44 151.6 18.1 2.3e-39 135.3 15.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG20098.1 - 0.00024 20.1 6.5 0.78 8.5 6.1 3.1 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 OAG20098.1 - 0.05 11.9 0.2 0.2 9.9 0.6 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAG20098.1 - 1.9 7.0 19.4 0.27 9.7 8.7 2.9 3 1 1 4 4 4 0 MFS/sugar transport protein RRM_1 PF00076.22 OAG20099.1 - 9.6e-23 79.8 2.4 2.4e-10 40.1 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG20099.1 - 4.8e-05 23.1 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OAG20099.1 - 0.001 19.3 2.5 2 8.6 0.0 3.1 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OAG20099.1 - 0.0017 18.4 0.1 1.3 9.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OAG20099.1 - 0.0031 17.1 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 OAG20099.1 - 0.0034 17.2 1.3 0.11 12.2 0.1 2.6 2 1 1 3 3 3 1 Calcipressin Exostosin PF03016.15 OAG20099.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Exostosin family DUF4523 PF15023.6 OAG20099.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.17 OAG20100.1 - 1.1e-70 237.4 2.8 1.6e-70 237.0 2.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 OAG20100.1 - 0.054 13.0 0.4 0.079 12.5 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 OAG20100.1 - 0.073 12.7 3.4 0.11 12.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CobA_CobO_BtuR PF02572.15 OAG20100.1 - 0.16 12.2 4.9 0.47 10.7 0.1 2.6 1 1 2 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Sec62 PF03839.16 OAG20100.1 - 1.8 8.0 6.2 3.2 7.2 6.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 TPR_14 PF13428.6 OAG20101.1 - 1.4e-11 44.2 18.8 3.1 8.9 0.0 11.6 9 3 3 12 12 10 2 Tetratricopeptide repeat Suf PF05843.14 OAG20101.1 - 1.8e-10 41.3 8.8 0.023 14.7 0.1 6.2 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 OAG20101.1 - 7.9e-08 31.9 4.6 0.00022 20.5 0.4 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAG20101.1 - 2e-06 27.8 14.5 0.45 10.5 0.2 7.3 6 1 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 OAG20101.1 - 2.8e-06 27.0 17.0 0.036 14.2 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG20101.1 - 4.4e-06 27.1 0.1 13 6.4 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG20101.1 - 1.3e-05 25.1 16.3 0.016 15.3 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat SNAP PF14938.6 OAG20101.1 - 0.00049 19.6 4.6 0.34 10.3 0.2 4.7 5 1 1 6 6 6 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OAG20101.1 - 0.0012 19.3 2.6 37 5.2 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 OAG20101.1 - 0.0019 18.0 0.8 0.018 14.7 0.3 2.9 3 1 0 3 3 3 1 26S proteasome subunit RPN7 NRDE-2 PF08424.10 OAG20101.1 - 0.02 14.0 0.5 0.02 14.0 0.5 4.9 3 3 0 4 4 4 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 OAG20101.1 - 0.028 14.4 1.5 1 9.5 0.0 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG20101.1 - 0.03 14.6 13.8 7.9 6.9 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat HAT PF02184.16 OAG20101.1 - 0.038 14.0 1.8 4.1 7.4 0.1 4.8 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.6 OAG20101.1 - 0.046 14.1 4.6 7.1 7.3 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat MIT PF04212.18 OAG20101.1 - 0.05 13.7 4.0 0.61 10.2 0.1 4.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain CKAP2_C PF15297.6 OAG20101.1 - 0.082 12.0 1.2 0.14 11.2 0.4 1.8 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus APOBEC_C PF05240.14 OAG20101.1 - 0.19 11.7 1.4 0.71 9.9 0.0 2.6 2 0 0 2 2 2 0 APOBEC-like C-terminal domain TPR_10 PF13374.6 OAG20101.1 - 0.3 11.0 11.0 1.1e+02 2.8 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Cytochrom_C_2 PF01322.20 OAG20101.1 - 2.7 8.9 5.9 33 5.4 1.0 3.6 3 1 0 3 3 3 0 Cytochrome C' SET PF00856.28 OAG20102.1 - 1.1e-12 48.7 0.0 5.5e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 SET domain CopK PF11525.8 OAG20102.1 - 0.14 11.8 0.2 1 9.0 0.1 2.4 3 0 0 3 3 3 0 Copper resistance protein K Phage_holin_2_4 PF16082.5 OAG20103.1 - 0.0014 18.3 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like MHC2-interact PF09307.10 OAG20103.1 - 0.0017 18.4 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting DUF4064 PF13273.6 OAG20103.1 - 0.0059 16.9 0.0 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) MoCF_biosynth PF00994.24 OAG20104.1 - 4e-53 179.0 0.1 3.2e-28 98.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAG20104.1 - 9e-41 139.3 1.5 1.5e-40 138.6 1.5 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) ATP-synt_C PF00137.21 OAG20104.1 - 2e-22 79.3 36.7 4e-15 55.9 9.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C MoeA_C PF03454.15 OAG20104.1 - 2e-18 66.3 0.8 5.3e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Oxidored_q2 PF00420.24 OAG20104.1 - 4.2 7.1 7.0 7.8 6.2 4.3 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TFIIA_gamma_C PF02751.14 OAG20105.1 - 3.4e-25 87.9 3.0 5.3e-25 87.3 3.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 OAG20105.1 - 9e-23 80.0 0.2 1.2e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EamA PF00892.20 OAG20106.1 - 0.00023 21.3 9.6 0.00027 21.1 9.6 1.1 1 0 0 1 1 1 1 EamA-like transporter family Wzy_C PF04932.15 OAG20106.1 - 0.039 13.6 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF3165 PF11364.8 OAG20106.1 - 0.097 13.0 0.5 0.13 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) TMEM234 PF10639.9 OAG20106.1 - 0.51 10.4 3.9 1.4 9.0 3.9 1.6 1 1 0 1 1 1 0 Putative transmembrane family 234 MCM_bind PF09739.9 OAG20107.1 - 0.0014 17.1 6.0 0.0018 16.8 6.0 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MMS1_N PF10433.9 OAG20108.1 - 1.9e-135 452.2 0.0 3e-135 451.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG20108.1 - 1.1e-76 258.3 0.0 5.9e-76 255.8 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region HPS3_N PF14761.6 OAG20108.1 - 0.028 14.0 0.9 0.95 9.0 0.3 2.9 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 YmzC PF14157.6 OAG20108.1 - 0.03 14.4 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 YmzC-like protein Ntox30 PF15532.6 OAG20108.1 - 0.04 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 30 RHS_repeat PF05593.14 OAG20108.1 - 0.11 13.1 0.7 4 8.0 0.0 3.4 3 0 0 3 3 3 0 RHS Repeat Sin_N PF04801.13 OAG20109.1 - 1.2e-29 103.8 2.5 6.9e-29 101.3 2.5 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region DUF4657 PF15552.6 OAG20109.1 - 0.022 14.3 0.8 0.041 13.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) RNase_H_2 PF13482.6 OAG20109.1 - 0.023 14.7 0.4 0.034 14.1 0.4 1.2 1 0 0 1 1 1 0 RNase_H superfamily Kri1 PF05178.12 OAG20109.1 - 0.26 11.9 4.2 0.55 10.8 4.2 1.6 1 0 0 1 1 1 0 KRI1-like family Glyco_hydro_2_N PF02837.18 OAG20110.1 - 4.3e-14 52.8 0.1 1.2e-11 44.9 0.2 3.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 OAG20110.1 - 1e-12 47.8 0.2 7.4e-11 41.7 0.2 2.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 OAG20110.1 - 3.1e-10 40.7 0.1 3.7e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG20110.1 - 0.21 12.2 1.6 0.89 10.2 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain DUF2293 PF10056.9 OAG20111.1 - 1.9e-31 108.2 0.3 3.9e-31 107.1 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_trans_4_2 PF13477.6 OAG20111.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Complex1_LYR PF05347.15 OAG20112.1 - 0.0014 18.7 3.2 0.0014 18.7 3.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) NFACT-R_1 PF05670.13 OAG20113.1 - 1.8e-41 141.2 0.2 2.6e-41 140.7 0.2 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 OAG20113.1 - 0.043 14.0 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 NFACT protein RNA binding domain MOZART1 PF12554.8 OAG20115.1 - 3.3e-23 81.2 0.6 3.9e-23 81.0 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Acetyltransf_1 PF00583.25 OAG20116.1 - 5.9e-08 33.0 0.2 1.1e-07 32.1 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 OAG20116.1 - 0.066 12.7 0.2 0.096 12.1 0.2 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_7 PF13508.7 OAG20116.1 - 0.11 12.9 0.1 0.29 11.6 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3851 PF12962.7 OAG20116.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Acetyltransf_CG PF14542.6 OAG20116.1 - 0.22 11.6 0.2 0.44 10.7 0.2 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 OAG20117.1 - 2.3e-49 168.1 0.0 5.8e-49 166.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20117.1 - 2.8e-23 82.6 0.0 5.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SAB PF04382.13 OAG20117.1 - 0.0027 17.7 1.4 0.0079 16.2 1.4 1.8 1 0 0 1 1 1 1 SAB domain APH PF01636.23 OAG20117.1 - 0.0059 16.6 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG20117.1 - 0.0081 15.5 0.0 0.081 12.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG20117.1 - 0.032 13.2 0.0 0.032 13.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Tim54 PF11711.8 OAG20117.1 - 7.9 5.2 7.8 0.37 9.5 1.2 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Svf1_C PF17187.4 OAG20118.1 - 2.7e-61 206.2 0.2 4.3e-61 205.5 0.2 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 OAG20118.1 - 7.6e-54 182.2 0.0 1.1e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CENP-T_C PF15511.6 OAG20119.1 - 0.00035 20.6 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAG20119.1 - 0.0004 20.5 0.1 0.00057 20.0 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) SBD_N PF07005.11 OAG20119.1 - 0.0054 16.5 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 Sugar-binding N-terminal domain Bromo_TP PF07524.13 OAG20119.1 - 0.039 14.0 0.1 0.29 11.2 0.0 2.0 1 1 1 2 2 2 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 OAG20119.1 - 0.061 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PrkA PF06798.12 OAG20119.1 - 0.07 12.8 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Histone PF00125.24 OAG20119.1 - 0.072 13.5 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HTH_17 PF12728.7 OAG20119.1 - 0.086 13.0 0.1 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DEK_C PF08766.11 OAG20119.1 - 0.098 12.6 1.7 1.2 9.2 0.4 2.6 2 1 1 3 3 3 0 DEK C terminal domain Mlh1_C PF16413.5 OAG20121.1 - 5.8e-99 330.8 0.0 1.1e-98 329.9 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAG20121.1 - 4.8e-34 116.6 0.1 8.1e-34 115.8 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG20121.1 - 2.2e-13 50.2 0.0 5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG20121.1 - 1.3e-06 28.9 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3533 PF12051.8 OAG20122.1 - 3.4e-115 385.0 18.5 4e-115 384.8 18.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1746 PF08508.10 OAG20122.1 - 9.5 6.6 9.4 0.4 11.0 2.5 2.2 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1746) Glyco_hydro_15 PF00723.21 OAG20123.1 - 1.8e-70 238.0 0.0 2.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ligase_CoA PF00549.19 OAG20124.1 - 7.9e-35 119.9 0.9 2.4e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 OAG20124.1 - 7.4e-18 65.0 0.6 3e-17 63.1 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 OAG20124.1 - 2.5e-09 37.0 0.1 4.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 OAG20124.1 - 0.11 13.3 0.1 9.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_2 PF08442.10 OAG20124.1 - 0.11 12.0 0.0 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain KilA-N PF04383.13 OAG20125.1 - 0.0082 16.0 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 KilA-N domain DUF769 PF05590.11 OAG20125.1 - 0.055 12.9 0.3 0.087 12.2 0.3 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Asp-B-Hydro_N PF05279.11 OAG20125.1 - 0.93 9.5 11.6 1.6 8.8 11.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rho_GDI PF02115.17 OAG20126.1 - 7e-63 211.9 0.7 7.7e-63 211.8 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Adaptin_N PF01602.20 OAG20128.1 - 4.2e-98 329.2 0.0 5.4e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG20128.1 - 7.3e-14 52.1 0.0 2.5e-12 47.1 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG20128.1 - 4e-06 27.1 3.0 0.0051 17.2 0.0 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 OAG20128.1 - 1.1e-05 25.3 0.7 4.3 7.9 0.0 6.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 OAG20128.1 - 0.18 12.3 1.1 19 5.9 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat RNA_pol_3_Rpc31 PF11705.8 OAG20128.1 - 0.23 11.7 18.3 0.37 11.0 12.7 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 OAG20128.1 - 3.9 7.3 11.8 3.3 7.5 0.2 2.6 2 0 0 2 2 2 0 Myc amino-terminal region FYDLN_acid PF09538.10 OAG20128.1 - 6.5 7.5 17.9 40 5.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 OAG20128.1 - 7.4 6.2 19.0 4.5 6.9 11.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Acyltransferase PF01553.21 OAG20129.1 - 1.7e-17 63.3 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 OAG20130.1 - 8.3e-13 48.6 4.6 0.097 13.6 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG20130.1 - 0.0094 16.2 0.1 0.5 10.7 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 OAG20131.1 - 2e-10 40.1 1.7 8.2e-10 38.0 1.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20131.1 - 9.4e-07 28.9 11.1 1.8e-06 28.0 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAG20131.1 - 0.00023 20.8 3.6 0.00052 19.7 3.6 1.6 1 0 0 1 1 1 1 Integrin plexin domain CCDC53 PF10152.9 OAG20131.1 - 7.8 6.9 12.0 0.025 15.0 1.2 2.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Fringe PF02434.16 OAG20132.1 - 3.5e-08 33.2 0.2 5.4e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 OAG20132.1 - 0.047 13.6 2.2 0.06 13.3 1.2 1.7 1 1 0 1 1 1 0 PAN domain ADH_N PF08240.12 OAG20133.1 - 1.5e-28 98.8 0.3 2.7e-28 98.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG20133.1 - 2.1e-23 82.7 0.0 3.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG20133.1 - 0.0025 17.3 0.8 0.006 16.1 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20133.1 - 0.005 17.9 0.0 0.0081 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG20133.1 - 0.02 14.2 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLTH PF10607.9 OAG20134.1 - 1e-32 113.0 0.1 1.3e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAG20134.1 - 5.1e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 LisH DUF5031 PF16434.5 OAG20134.1 - 0.056 12.6 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) Dec-1 PF04624.14 OAG20134.1 - 0.25 11.2 0.7 0.48 10.3 0.7 1.3 1 0 0 1 1 1 0 Dec-1 repeat PRK PF00485.18 OAG20135.1 - 3.5e-51 173.8 0.0 4.8e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 OAG20135.1 - 3.9e-40 137.5 0.0 6e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Metallophos PF00149.28 OAG20136.1 - 1.8e-36 126.5 0.3 2.5e-36 126.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG20136.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OAG20136.1 - 0.12 12.8 0.4 0.32 11.5 0.4 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain UPA_2 PF17809.1 OAG20137.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UPA domain Pmp3 PF01679.17 OAG20138.1 - 1.1e-18 67.1 5.7 1.5e-18 66.7 5.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Na_Ca_ex PF01699.24 OAG20140.1 - 1.1e-41 142.3 40.5 1.6e-21 76.8 18.4 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein HNF-1_N PF04814.13 OAG20140.1 - 1.5 9.4 3.9 3 8.4 3.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SNF2_N PF00176.23 OAG20141.1 - 2.4e-47 161.4 0.1 4.8e-47 160.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG20141.1 - 6.6e-10 39.3 0.0 1.5e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG20141.1 - 3.1e-05 24.1 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 OAG20141.1 - 0.0002 21.2 3.4 0.0002 21.2 3.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DEAD PF00270.29 OAG20141.1 - 0.0036 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase fn1 PF00039.18 OAG20141.1 - 0.073 13.3 0.4 0.19 11.9 0.4 1.7 1 0 0 1 1 1 0 Fibronectin type I domain zf-C3HC4_3 PF13920.6 OAG20141.1 - 0.12 12.3 8.1 0.23 11.4 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG20141.1 - 0.18 11.7 9.3 0.5 10.3 9.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG20141.1 - 0.18 11.8 7.4 0.42 10.6 7.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF883 PF05957.13 OAG20141.1 - 2.4 8.8 10.0 12 6.6 10.0 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Fungal_trans PF04082.18 OAG20142.1 - 1.3e-40 139.1 0.1 2.3e-40 138.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20142.1 - 5.8e-09 35.9 8.3 1.4e-08 34.7 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4503 PF14951.6 OAG20142.1 - 0.015 13.8 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) zf-C3HC4_2 PF13923.6 OAG20144.1 - 4.4e-09 36.0 11.3 4.4e-09 36.0 11.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG20144.1 - 3.1e-06 27.1 9.6 3.1e-06 27.1 9.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG20144.1 - 3.8e-06 26.8 16.7 1.2e-05 25.1 13.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG20144.1 - 4.6e-06 26.4 13.9 4.6e-06 26.4 13.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 OAG20144.1 - 1.9e-05 24.3 0.0 4.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 OAG20144.1 - 4.8e-05 23.1 18.0 0.00022 21.0 13.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAG20144.1 - 5.8e-05 22.9 8.4 0.00016 21.5 8.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.15 OAG20144.1 - 0.00044 20.4 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 OAG20144.1 - 0.00091 19.5 12.9 0.00091 19.5 12.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAG20144.1 - 0.0018 18.4 13.4 0.0018 18.4 13.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG20144.1 - 0.016 15.1 17.9 0.27 11.1 14.0 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG20144.1 - 0.019 15.2 6.7 0.019 15.2 6.7 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAG20144.1 - 0.026 14.6 8.3 0.074 13.2 8.3 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Mob_synth_C PF06463.13 OAG20144.1 - 0.15 12.0 4.6 0.43 10.5 4.6 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C ThiF PF00899.21 OAG20145.1 - 1.7e-12 47.2 0.0 2.5e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.14 OAG20146.1 - 4.7e-42 143.5 0.0 9.2e-42 142.6 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OAG20146.1 - 0.0073 16.3 0.3 1.8 8.5 0.1 2.4 1 1 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 OAG20146.1 - 0.046 12.9 0.1 0.08 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_61 PF03443.14 OAG20147.1 - 8.7e-51 172.8 0.0 2.3e-50 171.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 TPR_12 PF13424.6 OAG20148.1 - 0.084 13.2 0.3 1.7 9.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG20148.1 - 0.18 12.5 1.0 0.74 10.5 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 OAG20149.1 - 1.1e-43 149.0 0.2 1.7e-43 148.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG20149.1 - 4e-21 75.4 0.1 1.7e-20 73.4 0.0 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG20149.1 - 1.3e-16 60.5 0.9 3e-16 59.4 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAG20149.1 - 5.7e-07 29.7 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG20149.1 - 7.4e-05 22.1 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2362 PF10154.9 OAG20149.1 - 0.028 13.4 0.2 0.048 12.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Pantoate_ligase PF02569.15 OAG20150.1 - 1.3e-90 303.3 0.0 1.5e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 OAG20150.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Fungal_trans PF04082.18 OAG20151.1 - 2.5e-30 105.4 0.0 3.3e-29 101.8 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20151.1 - 8e-08 32.3 9.3 1.3e-07 31.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 OAG20153.1 - 7.4e-129 430.2 0.0 8.3e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG20153.1 - 0.00012 21.3 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Nipped-B_C PF12830.7 OAG20155.1 - 5.4e-43 147.2 4.0 3.5e-41 141.2 0.5 3.5 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OAG20155.1 - 9.9e-10 38.5 0.7 3e-09 37.0 0.7 1.9 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 OAG20155.1 - 2.2e-05 24.6 0.1 0.0001 22.4 0.1 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG20155.1 - 0.015 15.5 0.0 2.9 8.4 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 OAG20155.1 - 0.039 14.5 0.3 4.5 7.9 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat FANCI_S3 PF14677.6 OAG20155.1 - 0.36 10.5 2.0 0.7 9.6 0.1 2.5 2 0 0 2 2 2 0 FANCI solenoid 3 TFIIS_C PF01096.18 OAG20156.1 - 2.7e-16 59.1 2.4 2.7e-16 59.1 2.4 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAG20156.1 - 1.5e-05 24.8 1.5 1.5e-05 24.8 1.5 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit UCH_1 PF13423.6 OAG20156.1 - 0.01 15.5 1.9 0.011 15.3 1.9 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase C1_1 PF00130.22 OAG20156.1 - 0.016 15.1 0.9 0.016 15.1 0.9 2.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) tRNA-synt_1f PF01921.18 OAG20156.1 - 0.028 13.4 0.4 0.028 13.4 0.4 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) NOB1_Zn_bind PF08772.11 OAG20156.1 - 0.05 13.8 5.7 7.3 6.8 0.3 3.3 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like eIF-5_eIF-2B PF01873.17 OAG20156.1 - 0.084 12.8 3.2 0.38 10.7 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_2 PF13240.6 OAG20156.1 - 0.26 11.1 14.6 2.5 7.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 OAG20156.1 - 0.4 10.7 11.4 0.14 12.2 3.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OAG20156.1 - 0.53 9.9 8.2 3 7.4 0.3 3.5 3 1 1 4 4 4 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 OAG20156.1 - 1.8 9.0 12.3 1.4 9.3 0.8 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-trcl PF13451.6 OAG20156.1 - 2.3 8.2 8.7 9.6 6.2 0.1 3.4 2 1 1 3 3 3 0 Probable zinc-ribbon domain HEAT_2 PF13646.6 OAG20157.1 - 2e-27 95.4 5.3 3.6e-12 46.5 0.1 3.8 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 OAG20157.1 - 3.2e-19 67.6 4.2 0.0044 17.6 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 OAG20157.1 - 1.6e-06 28.5 9.3 1.2 9.7 0.1 6.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.22 OAG20157.1 - 5.6e-06 26.2 8.5 1.4 9.3 0.0 6.1 8 0 0 8 8 8 3 HEAT repeat Cohesin_HEAT PF12765.7 OAG20157.1 - 0.036 14.4 0.1 3.3 8.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 OAG20157.1 - 0.044 13.8 0.0 2.1 8.3 0.0 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 OAG20157.1 - 0.24 9.8 0.0 40 2.4 0.0 3.0 3 0 0 3 3 3 0 Lipoprotein amino terminal region PUB_1 PF18486.1 OAG20157.1 - 0.57 10.1 0.1 0.57 10.1 0.1 2.7 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain NUDE_C PF04880.13 OAG20158.1 - 0.014 15.9 3.1 0.024 15.1 3.1 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Glyco_hydro_11 PF00457.17 OAG20160.1 - 2.1e-80 268.5 20.0 2.5e-80 268.3 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Aminotran_3 PF00202.21 OAG20161.1 - 1.8e-81 273.9 0.0 2.2e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short_C2 PF13561.6 OAG20162.1 - 2.2e-47 161.6 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20162.1 - 1.9e-44 151.5 0.2 2.3e-44 151.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20162.1 - 1.9e-10 40.9 0.2 2.7e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG20162.1 - 0.00015 21.1 0.2 0.0058 16.0 0.0 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-MYND PF01753.18 OAG20164.1 - 2.3e-09 37.2 10.8 4e-09 36.4 10.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OAG20164.1 - 3.2 7.9 8.1 12 6.0 8.1 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SKG6 PF08693.10 OAG20165.1 - 0.00028 20.2 2.1 0.00048 19.5 2.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG20165.1 - 0.0091 16.9 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cpn60_TCP1 PF00118.24 OAG20166.1 - 4.2e-154 513.8 17.9 4.8e-154 513.6 17.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 OAG20167.1 - 5.5e-24 84.2 0.1 1.1e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OAG20167.1 - 1.8e-18 67.1 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG20167.1 - 2.5e-18 66.0 0.0 5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain MqsR_toxin PF15723.5 OAG20167.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Proteasom_Rpn13 PF04683.13 OAG20169.1 - 7.6e-27 93.7 0.0 1.3e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 OAG20169.1 - 5.2e-09 36.3 1.4 4.9e-08 33.1 1.4 2.1 1 1 0 1 1 1 1 UCH-binding domain Ribosomal_L6e PF01159.19 OAG20170.1 - 1.6e-39 134.8 0.4 1.6e-39 134.8 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 OAG20170.1 - 0.0063 15.9 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 DUF3544 PF12064.8 OAG20170.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 0 Protein kinase C-binding protein 1 KOW PF00467.29 OAG20170.1 - 0.046 13.7 0.6 0.16 12.0 0.3 2.0 2 0 0 2 2 2 0 KOW motif FA_hydroxylase PF04116.13 OAG20171.1 - 6.3e-15 55.7 6.1 6.3e-15 55.7 6.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HTH_psq PF05225.16 OAG20172.1 - 4.8e-06 26.2 0.2 6e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 OAG20172.1 - 0.06 13.5 0.9 0.085 13.0 0.9 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 OAG20173.1 - 4.2e-28 97.9 0.1 8e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20173.1 - 1.4e-17 65.0 0.1 3.7e-17 63.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG20173.1 - 5.3e-08 32.7 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OAG20173.1 - 0.00035 20.1 0.1 0.00057 19.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N_2 PF16884.5 OAG20173.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF3318 PF11780.8 OAG20173.1 - 0.26 11.2 1.4 0.52 10.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) HTH_AsnC-type PF13404.6 OAG20174.1 - 0.0073 16.1 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain Exo84_C PF16528.5 OAG20175.1 - 1.5e-70 237.2 3.3 1.5e-70 237.2 3.3 1.7 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAG20175.1 - 3.7e-16 59.0 3.6 3.7e-16 59.0 3.6 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 OAG20175.1 - 0.32 11.1 3.8 0.19 11.8 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BST2 PF16716.5 OAG20175.1 - 0.42 11.2 6.7 0.69 10.5 2.0 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 MAS20 PF02064.15 OAG20176.1 - 1.4e-49 167.5 1.2 1.6e-49 167.3 1.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor HPTransfase PF10090.9 OAG20176.1 - 0.0095 15.7 0.3 0.021 14.6 0.3 1.5 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain PSK_trans_fac PF07704.11 OAG20176.1 - 0.039 14.7 1.6 0.064 14.0 1.6 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor TetR_C_15 PF17918.1 OAG20176.1 - 0.14 13.0 0.3 0.23 12.2 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Nucleolin_bd PF16725.5 OAG20176.1 - 0.14 11.9 0.3 0.14 11.9 0.3 1.7 2 0 0 2 2 2 0 Nucleolin binding domain DctM PF06808.12 OAG20176.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component PMC2NT PF08066.12 OAG20176.1 - 0.17 12.6 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Frankia_peptide PF14407.6 OAG20176.1 - 0.21 11.6 2.0 6.2 6.9 0.2 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Ras PF00071.22 OAG20177.1 - 1.8e-59 199.9 0.5 2.3e-59 199.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG20177.1 - 5e-37 126.8 0.2 9e-37 126.0 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG20177.1 - 9.6e-18 64.2 0.3 1.2e-17 63.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG20177.1 - 2.6e-06 27.1 0.2 3.2e-05 23.5 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAG20177.1 - 5.1e-06 26.0 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG20177.1 - 1.8e-05 24.8 0.1 2.9e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG20177.1 - 2.6e-05 23.7 0.2 3.4e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAG20177.1 - 4.2e-05 23.5 0.6 0.024 14.6 0.3 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OAG20177.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAG20177.1 - 0.13 12.5 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nop53 PF07767.11 OAG20178.1 - 1.5e-100 337.4 41.6 1.8e-100 337.2 41.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.16 OAG20180.1 - 7.7e-33 113.9 18.1 3e-32 111.9 16.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TssN PF17555.2 OAG20180.1 - 3.9 6.8 7.4 0.46 9.8 1.2 2.3 3 0 0 3 3 3 0 Type VI secretion system, TssN DUF1295 PF06966.12 OAG20181.1 - 9.8e-31 107.1 0.1 1.3e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAG20181.1 - 0.00026 21.0 0.1 0.00054 20.0 0.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAG20181.1 - 0.016 15.6 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG20181.1 - 0.028 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Phospholipid methyltransferase Mucin-like PF16058.5 OAG20181.1 - 0.39 10.8 5.1 0.69 10.0 5.1 1.3 1 0 0 1 1 1 0 Mucin-like DUF1656 PF07869.12 OAG20181.1 - 4.6 7.3 6.3 19 5.4 0.2 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1656) Ribonuc_L-PSP PF01042.21 OAG20182.1 - 4.7e-13 49.2 0.0 2.2e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Endoribonuclease L-PSP SnoaL_3 PF13474.6 OAG20183.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 OAG20183.1 - 0.13 12.9 0.0 0.32 11.7 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain Arginase PF00491.21 OAG20184.1 - 2e-60 204.7 0.0 8.3e-45 153.4 0.0 2.0 1 1 1 2 2 2 2 Arginase family Cyt-b5 PF00173.28 OAG20185.1 - 0.0023 18.0 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 OAG20186.1 - 1e-61 204.6 6.5 4.3e-19 68.1 0.2 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG20186.1 - 8.7e-06 25.3 0.0 0.078 12.6 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG20186.1 - 3.9e-05 24.0 6.9 2.5 8.3 0.0 6.0 4 3 2 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OAG20186.1 - 4e-05 23.7 0.3 0.76 9.9 0.1 4.0 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 OAG20186.1 - 0.0049 16.9 1.3 0.2 11.8 0.4 3.6 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 OAG20186.1 - 0.045 13.6 0.0 0.88 9.5 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif BCAS3 PF12490.8 OAG20186.1 - 5.7 6.4 7.8 0.29 10.6 0.4 2.4 3 0 0 3 3 3 0 Breast carcinoma amplified sequence 3 MFS_1 PF07690.16 OAG20187.1 - 2.7e-25 89.0 42.4 3.7e-16 59.0 13.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20187.1 - 2.1e-18 66.5 17.3 8.4e-18 64.5 17.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.27 OAG20189.1 - 3.2e-19 69.8 0.0 5.6e-09 36.6 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG20189.1 - 2.7e-08 34.0 0.1 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAG20189.1 - 0.00031 20.9 0.0 0.0054 16.9 0.1 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAG20189.1 - 0.11 12.9 0.4 0.11 12.9 0.4 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG20189.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 OAG20189.1 - 0.15 9.5 0.1 0.25 8.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DNAP_B_exo_N PF08452.10 OAG20189.1 - 0.23 10.9 1.0 0.57 9.6 1.0 1.6 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal AAA_13 PF13166.6 OAG20189.1 - 0.27 9.9 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 OAG20190.1 - 6.5e-35 121.1 0.0 2.4e-34 119.2 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain LCM PF04072.14 OAG20190.1 - 2.7e-21 76.4 0.0 4.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 OAG20190.1 - 1.1e-16 60.6 8.2 5.4e-06 26.3 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG20190.1 - 7.7e-08 32.2 2.0 0.0045 16.9 0.1 4.4 6 0 0 6 6 6 2 Kelch motif Cupin_4 PF08007.12 OAG20190.1 - 3.8e-06 26.6 0.0 7.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 OAG20190.1 - 0.0001 22.5 1.2 0.029 14.7 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain ANAPC4_WD40 PF12894.7 OAG20191.1 - 0.00013 22.2 0.0 2.1 8.7 0.0 4.5 3 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG20191.1 - 0.00085 20.1 0.0 0.032 15.1 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat BBS2_N PF14781.6 OAG20191.1 - 0.005 16.7 0.0 7.5 6.5 0.0 3.9 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 OAG20191.1 - 0.03 13.3 0.0 0.091 11.7 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PI31_Prot_N PF11566.8 OAG20192.1 - 8.1e-54 181.8 0.0 1.1e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAG20192.1 - 3.5e-18 66.5 18.3 3.5e-18 66.5 18.3 3.4 3 1 0 3 3 3 1 PI31 proteasome regulator zf-C2H2_4 PF13894.6 OAG20194.1 - 1.4e-09 38.0 13.1 0.0029 18.3 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG20194.1 - 2.2e-09 37.2 14.8 0.0013 19.1 1.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG20194.1 - 2.9e-05 24.3 9.7 0.036 14.5 0.1 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 OAG20194.1 - 0.042 14.2 0.7 0.43 11.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.21 OAG20194.1 - 0.088 13.0 1.0 0.19 12.0 1.0 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 OAG20194.1 - 0.11 12.8 8.8 0.12 12.6 3.7 2.3 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 OAG20194.1 - 0.7 9.9 4.0 0.93 9.5 0.4 2.8 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.6 OAG20194.1 - 1.9 8.3 7.5 0.41 10.4 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_10 PF18414.1 OAG20194.1 - 3.4 7.3 6.6 0.16 11.5 0.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger Dexa_ind PF15198.6 OAG20195.1 - 0.084 13.0 3.1 2.5 8.2 0.3 2.6 2 0 0 2 2 2 0 Dexamethasone-induced DUF3112 PF11309.8 OAG20197.1 - 2.4e-12 46.8 2.0 9e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Phage_holin_4_1 PF05105.12 OAG20197.1 - 0.32 11.1 4.3 0.47 10.6 0.4 2.4 2 1 0 2 2 2 0 Bacteriophage holin family Hemerythrin PF01814.23 OAG20198.1 - 4.9e-11 43.4 2.1 7.2e-11 42.8 2.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dcc1 PF09724.9 OAG20199.1 - 1.3e-35 123.3 0.0 1.6e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 OAG20200.1 - 4.1e-23 82.6 0.0 9.6e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Nod1 PF17114.5 OAG20200.1 - 2.8e-05 24.3 0.0 6.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 DUF3507 PF12015.8 OAG20200.1 - 0.00072 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) NleF_casp_inhib PF16809.5 OAG20200.1 - 0.033 14.1 1.5 0.82 9.6 0.3 2.7 2 0 0 2 2 2 0 NleF caspase inhibitor PikAIV_N PF18605.1 OAG20200.1 - 0.057 13.0 2.4 1.4 8.6 1.3 3.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AD PF09793.9 OAG20200.1 - 0.074 13.2 0.3 1.1 9.4 0.0 3.0 3 0 0 3 3 3 0 Anticodon-binding domain Seadorna_VP6 PF07407.11 OAG20200.1 - 0.17 10.8 0.6 0.27 10.1 0.6 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein NRBF2 PF08961.10 OAG20200.1 - 0.24 11.0 9.2 0.025 14.2 4.1 2.0 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF948 PF06103.11 OAG20200.1 - 0.68 10.2 5.9 0.52 10.6 0.1 2.9 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 OAG20200.1 - 1.1 9.6 3.5 6.5 7.2 1.2 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 OAG20200.1 - 1.6 7.3 4.1 2.3 6.7 3.5 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2959 PF11172.8 OAG20200.1 - 2.2 8.4 11.5 0.8 9.8 3.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) PRKG1_interact PF15898.5 OAG20200.1 - 4.4 8.2 21.9 6.9 7.6 10.6 3.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 OAG20200.1 - 5.3 6.3 17.0 1.1e+02 2.0 17.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nup84_Nup100 PF04121.13 OAG20202.1 - 2.4e-132 442.5 2.4 3.2e-132 442.1 2.4 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PEX11 PF05648.14 OAG20202.1 - 0.056 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Med15_fungi PF05397.12 OAG20202.1 - 0.45 10.8 1.9 1.3 9.3 0.6 2.5 2 0 0 2 2 2 0 Mediator complex subunit 15 MTCP1 PF08991.10 OAG20203.1 - 1.5e-28 98.8 10.9 1.7e-28 98.6 10.9 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 OAG20203.1 - 0.00092 19.3 6.1 0.00092 19.3 6.1 1.7 2 0 0 2 2 2 1 CHCH domain PET122 PF05476.11 OAG20203.1 - 0.03 13.6 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 PET122 Cmc1 PF08583.10 OAG20203.1 - 0.034 14.2 2.7 0.034 14.2 2.7 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.8 OAG20204.1 - 2.2e-17 62.6 0.1 2.7e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG20204.1 - 1e-09 38.0 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ion_trans PF00520.31 OAG20206.1 - 7.8e-09 35.1 25.3 2.3e-08 33.6 25.3 1.8 1 1 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.17 OAG20207.1 - 3.1e-113 376.5 0.2 1.2e-82 276.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 OAG20207.1 - 3e-47 160.9 0.0 6.8e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAG20207.1 - 1.4e-46 157.4 0.0 3.1e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAG20207.1 - 7.3e-45 152.6 0.0 1.7e-44 151.4 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 OAG20207.1 - 6.1e-41 139.6 0.1 1.6e-40 138.2 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAG20207.1 - 1.4e-33 116.2 0.1 4.1e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 OAG20207.1 - 1.5e-19 70.0 0.0 8.2e-19 67.6 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 OAG20207.1 - 6.7e-17 61.7 0.4 4.2e-08 33.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG20207.1 - 4.4e-15 55.7 0.1 5.3e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAG20207.1 - 1.9e-09 37.4 0.0 7e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 OAG20207.1 - 2.3e-05 24.3 0.0 0.0053 16.5 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 OAG20207.1 - 5.2e-05 23.4 0.4 0.15 12.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 OAG20207.1 - 0.00016 21.5 0.0 0.0052 16.6 0.0 2.8 2 0 0 2 2 2 1 DJ-1/PfpI family GARS_A PF01071.19 OAG20207.1 - 0.00072 19.4 0.1 1.5 8.6 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Synaptobrevin PF00957.21 OAG20208.1 - 6.6e-31 106.0 0.1 9.5e-31 105.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG20208.1 - 3.4e-21 75.1 0.0 6.1e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF5542 PF17696.1 OAG20208.1 - 0.089 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5542) RNase_P_Rpp14 PF01900.19 OAG20209.1 - 2.8e-37 127.1 0.0 4.1e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family She9_MDM33 PF05546.11 OAG20210.1 - 2.2e-57 194.1 8.2 3.5e-57 193.4 8.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PARM PF17061.5 OAG20210.1 - 0.0012 19.1 6.9 0.0012 19.1 6.9 1.7 2 0 0 2 2 2 1 PARM DUF2564 PF10819.8 OAG20210.1 - 0.028 14.8 8.0 0.082 13.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Virulence_fact PF13769.6 OAG20210.1 - 2.1 8.6 8.6 1.5 9.1 0.1 3.7 3 1 0 3 3 3 0 Virulence factor Exonuc_VII_L PF02601.15 OAG20210.1 - 6.8 6.2 13.4 2.5 7.6 8.7 2.5 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF883 PF05957.13 OAG20210.1 - 9.4 6.9 15.7 5.9 7.6 0.7 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HAD PF12710.7 OAG20211.1 - 1.5e-22 80.9 0.0 2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG20211.1 - 0.002 17.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 OAG20211.1 - 0.02 14.4 0.0 0.11 12.0 0.0 2.1 2 1 1 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) HKR_ArcB_TM PF18415.1 OAG20212.1 - 5.4 7.9 7.5 0.72 10.7 1.2 2.6 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Tyrosinase PF00264.20 OAG20213.1 - 2.1e-50 172.1 3.0 3.5e-50 171.4 3.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1681 PF07933.14 OAG20214.1 - 7.3e-55 184.7 0.0 1.1e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Neuromodulin_N PF10580.9 OAG20214.1 - 0.0068 16.2 2.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Gap junction protein N-terminal region Tom5 PF10642.9 OAG20214.1 - 2.3 8.3 4.6 5 7.2 0.0 3.2 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase GILT PF03227.16 OAG20215.1 - 4.6e-18 65.4 0.1 7.6e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) CTXphi_pIII-N1 PF16710.5 OAG20215.1 - 0.037 14.1 0.3 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Hexokinase_1 PF00349.21 OAG20216.1 - 2.5e-51 174.4 0.0 3.9e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAG20216.1 - 2.9e-51 174.2 0.0 3.9e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Syja_N PF02383.18 OAG20217.1 - 4.4e-79 266.1 0.1 1.1e-78 264.8 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain Abhydrolase_6 PF12697.7 OAG20218.1 - 3e-08 34.6 1.9 1.2e-07 32.6 1.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG20218.1 - 1.5e-06 28.1 0.0 7e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG20218.1 - 0.00044 19.6 0.0 0.067 12.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Glyco_hydro_125 PF06824.11 OAG20219.1 - 1.4e-181 604.0 0.0 1.6e-181 603.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CLP1_P PF16575.5 OAG20220.1 - 3.2e-35 121.6 0.0 7.4e-35 120.5 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 OAG20220.1 - 1.3e-33 115.1 0.0 2.2e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OAG20220.1 - 1.9e-25 89.5 0.0 3.3e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 OAG20220.1 - 1.9e-05 24.6 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG20220.1 - 0.00072 19.6 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG20220.1 - 0.002 17.6 0.1 0.0073 15.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAG20220.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAG20220.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OAG20220.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 OAG20220.1 - 0.034 14.3 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_35 PF14516.6 OAG20220.1 - 0.048 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 OAG20220.1 - 0.092 13.3 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 OAG20220.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 OAG20220.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 OAG20220.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein F-box PF00646.33 OAG20221.1 - 0.00077 19.3 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 OAG20221.1 - 0.028 14.4 0.2 0.86 9.6 0.0 2.8 3 0 0 3 3 3 0 F-box-like domain MRP-S32 PF10210.9 OAG20221.1 - 0.29 11.7 1.5 1.5 9.4 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S32 Aldo_ket_red PF00248.21 OAG20223.1 - 1.6e-68 231.1 0.0 1.9e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L6 PF00347.23 OAG20224.1 - 4e-27 94.7 5.4 8.6e-14 52.0 1.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 UPF0086 PF01868.16 OAG20225.1 - 1.4e-15 56.9 0.1 2.6e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 RTA1 PF04479.13 OAG20226.1 - 3.8e-39 134.4 6.2 1.5e-38 132.5 6.2 1.8 1 1 0 1 1 1 1 RTA1 like protein Arb1 PF09692.10 OAG20227.1 - 5.4e-125 417.7 0.0 7.2e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 OAG20227.1 - 3e-16 59.2 0.0 5.7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 La domain IPK PF03770.16 OAG20228.1 - 2.7e-59 200.4 0.0 3.4e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Zn_clus PF00172.18 OAG20229.1 - 2.9e-05 24.1 10.7 6.7e-05 22.9 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 OAG20229.1 - 8.4 7.0 11.0 13 6.3 1.3 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.16 OAG20230.1 - 1.4e-20 73.6 54.9 8.8e-19 67.6 48.6 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Spherulin4 PF12138.8 OAG20231.1 - 4.8e-61 206.5 0.0 5.4e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 F-box-like PF12937.7 OAG20232.1 - 0.068 13.1 0.3 0.25 11.3 0.3 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAG20232.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.5 3 0 0 3 3 3 0 F-box domain Sigma54_AID PF00309.20 OAG20233.1 - 0.021 14.7 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Astacin PF01400.24 OAG20234.1 - 6.2e-09 35.8 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 OAG20234.1 - 0.0041 17.3 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAG20234.1 - 0.013 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 OAG20234.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OAG20234.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OAG20234.1 - 0.049 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 OAG20234.1 - 0.056 14.0 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like BTB_2 PF02214.22 OAG20235.1 - 1e-08 35.4 0.0 2.5e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 OAG20236.1 - 1.6e-10 40.9 9.3 2.4e-10 40.3 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG20236.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Rod_C PF10493.9 OAG20238.1 - 0.038 12.4 0.0 0.083 11.3 0.0 1.5 1 0 0 1 1 1 0 Rough deal protein C-terminal region PTR2 PF00854.21 OAG20240.1 - 5.8e-81 272.3 7.9 7.7e-81 271.9 7.9 1.2 1 0 0 1 1 1 1 POT family Bac_rhodopsin PF01036.18 OAG20240.1 - 0.79 9.3 8.8 0.26 10.8 0.2 3.1 3 0 0 3 3 3 0 Bacteriorhodopsin-like protein DUF2457 PF10446.9 OAG20241.1 - 0.24 10.5 0.4 0.26 10.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_S9 PF00326.21 OAG20242.1 - 3.1e-48 164.1 0.6 5e-48 163.4 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG20242.1 - 0.033 14.1 1.8 34 4.6 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2920 PF11144.8 OAG20242.1 - 0.048 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CdvA PF18822.1 OAG20243.1 - 0.044 13.6 1.8 0.066 13.0 0.6 1.8 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Phage_TAC_10 PF10963.8 OAG20243.1 - 0.11 12.7 0.3 0.23 11.7 0.3 1.8 1 1 0 1 1 1 0 Phage tail assembly chaperone DUF1518 PF07469.12 OAG20244.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) Glyco_hydro_67M PF07488.12 OAG20245.1 - 2.1e-140 467.4 0.1 3.2e-140 466.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 OAG20245.1 - 1.2e-87 293.2 1.7 1.7e-87 292.6 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 OAG20245.1 - 3.9e-27 95.0 0.0 8.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 OAG20245.1 - 0.087 13.6 0.1 0.24 12.2 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 OAG20245.1 - 0.15 11.4 0.3 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) PT-TG PF14449.6 OAG20245.1 - 0.44 10.5 1.6 10 6.1 0.0 3.2 4 0 0 4 4 4 0 Pre-toxin TG Ank_2 PF12796.7 OAG20246.1 - 2.4e-13 50.4 0.0 5.9e-11 42.8 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG20246.1 - 4.1e-12 46.4 0.3 4.7e-05 23.9 0.1 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG20246.1 - 2e-08 34.3 0.1 0.0016 18.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OAG20246.1 - 3.9e-08 32.9 0.1 0.0012 19.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG20246.1 - 1.1e-07 31.9 0.1 1.8e-06 28.1 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) SesA PF17107.5 OAG20246.1 - 0.0034 17.6 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Aldedh PF00171.22 OAG20247.1 - 1.4e-151 505.2 0.4 1.5e-151 505.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG20247.1 - 0.0038 16.7 0.2 0.45 9.9 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAG20247.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MBA1 PF07961.11 OAG20248.1 - 0.0069 15.5 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein zf-C2H2 PF00096.26 OAG20250.1 - 2e-11 43.7 54.9 0.28 11.7 0.1 10.9 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG20250.1 - 1.1e-07 32.0 57.3 0.082 13.8 0.3 11.3 11 0 0 11 11 11 4 C2H2-type zinc finger zf-met PF12874.7 OAG20250.1 - 0.00048 20.4 40.7 0.17 12.3 0.1 9.1 11 0 0 11 11 11 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG20250.1 - 0.0065 16.7 2.0 0.057 13.7 0.2 8.0 10 1 0 10 10 10 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OAG20250.1 - 4.9 7.0 0.0 4.9 7.0 0.0 5.3 5 1 0 5 5 5 0 C2H2-type zinc-finger domain Myb_DNA-binding PF00249.31 OAG20251.1 - 1.8e-07 31.2 3.1 2.4e-07 30.9 1.8 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG20251.1 - 1.3e-06 28.5 3.8 1.3e-06 28.5 3.8 2.6 3 1 0 3 3 3 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 OAG20251.1 - 0.023 14.5 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain EMP24_GP25L PF01105.24 OAG20252.1 - 1.1e-47 162.3 0.2 1.3e-47 162.1 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IcmF_C PF06744.12 OAG20253.1 - 0.77 9.3 3.4 0.6 9.7 0.4 2.0 2 0 0 2 2 2 0 Type VI secretion protein IcmF C-terminal Sulfate_transp PF00916.20 OAG20256.1 - 2.3e-85 286.6 16.8 3e-85 286.3 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG20256.1 - 6.4e-12 45.1 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_1 PF07690.16 OAG20257.1 - 2.5e-20 72.7 34.4 1.8e-16 60.0 17.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20257.1 - 3e-19 69.2 12.5 2e-18 66.5 11.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4746 PF15928.5 OAG20259.1 - 0.087 12.2 3.7 0.09 12.2 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HAUS6_N PF14661.6 OAG20259.1 - 0.24 10.9 8.0 0.3 10.6 8.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glutaredoxin PF00462.24 OAG20260.1 - 2.3e-12 46.9 0.0 7.8e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OAG20260.1 - 3.9e-06 26.8 2.6 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 F plasmid transfer operon protein tRNA_anti-like PF12869.7 OAG20260.1 - 0.0013 18.4 0.7 0.0017 18.0 0.7 1.3 1 0 0 1 1 1 1 tRNA_anti-like Connexin PF00029.19 OAG20260.1 - 0.046 13.5 0.6 0.073 12.8 0.6 1.3 1 0 0 1 1 1 0 Connexin Nucleoside_tran PF01733.18 OAG20260.1 - 0.054 12.9 0.2 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Nucleoside transporter Thioredoxin_2 PF13098.6 OAG20260.1 - 0.14 12.7 0.6 0.6 10.6 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain GST_N_3 PF13417.6 OAG20260.1 - 0.15 12.5 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Zip PF02535.22 OAG20260.1 - 0.2 10.8 0.3 0.23 10.6 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 OAG20260.1 - 0.28 10.1 1.3 0.36 9.7 1.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 OAG20260.1 - 1 8.0 2.6 1.4 7.6 2.6 1.2 1 0 0 1 1 1 0 Presenilin PhyH PF05721.13 OAG20261.1 - 6.9e-13 49.3 0.0 9.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ycf9 PF01737.17 OAG20261.1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 YCF9 PalH PF08733.10 OAG20262.1 - 0.00071 18.7 1.0 0.00071 18.7 1.0 1.4 2 0 0 2 2 2 1 PalH/RIM21 GMC_oxred_N PF00732.19 OAG20263.1 - 3e-54 184.4 0.0 6.1e-54 183.4 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG20263.1 - 4.8e-32 111.5 0.2 8.3e-32 110.7 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG20263.1 - 1.7e-05 24.6 0.3 0.00056 19.6 0.0 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG20263.1 - 2.7e-05 24.3 0.0 6.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG20263.1 - 3.7e-05 23.0 0.0 7.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG20263.1 - 0.021 14.1 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG20263.1 - 0.037 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 OAG20263.1 - 0.13 12.9 0.0 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4690 PF15756.5 OAG20264.1 - 0.064 13.9 0.5 0.064 13.9 0.5 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF4834 PF16118.5 OAG20264.1 - 0.16 13.0 0.0 1.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MtrF PF09472.10 OAG20264.1 - 0.22 10.9 1.9 0.53 9.7 1.9 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.20 OAG20264.1 - 2.8 7.9 5.3 6.3 6.8 5.3 1.5 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 OAG20264.1 - 3.4 7.7 5.8 0.58 10.2 1.3 1.9 2 1 0 2 2 2 0 Podoplanin Adeno_E3_CR2 PF02439.15 OAG20264.1 - 7.6 6.4 6.8 18 5.2 6.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Clr5 PF14420.6 OAG20265.1 - 9e-14 51.4 0.4 2.6e-13 50.0 0.4 1.8 1 0 0 1 1 1 1 Clr5 domain ThiF PF00899.21 OAG20266.1 - 1.5e-110 368.3 0.0 1.5e-76 257.0 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAG20266.1 - 2.5e-92 309.4 1.3 5.2e-92 308.3 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 OAG20266.1 - 3.5e-31 107.8 0.2 7e-31 106.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 OAG20266.1 - 4.8e-31 106.8 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OAG20266.1 - 7.2e-24 83.8 2.3 7.2e-24 83.8 2.3 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle ParA PF10609.9 OAG20267.1 - 6.6e-94 314.0 0.0 7.7e-94 313.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG20267.1 - 1.4e-06 28.4 0.0 9.9e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAG20267.1 - 2.7e-05 24.1 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAG20267.1 - 0.00057 19.2 1.6 0.0015 17.7 0.6 2.0 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 OAG20267.1 - 0.012 15.5 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAG20267.1 - 0.029 14.3 0.4 0.066 13.1 0.4 1.5 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 OAG20267.1 - 0.042 13.1 0.0 0.1 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 OAG20267.1 - 0.057 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Rad17 PF03215.15 OAG20267.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 OAG20267.1 - 0.23 10.6 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoD PF09423.10 OAG20268.1 - 5.3e-06 25.7 0.7 0.0004 19.5 0.3 2.6 2 1 0 2 2 2 2 PhoD-like phosphatase FAD_binding_4 PF01565.23 OAG20269.1 - 1.4e-18 67.0 1.2 2.6e-18 66.1 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG20269.1 - 2.1e-13 50.2 0.0 4.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 OAG20270.1 - 1e-08 35.1 14.0 1.8e-08 34.3 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 OAG20271.1 - 7.9e-113 377.0 0.0 9.5e-113 376.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG20271.1 - 5.7e-19 68.0 0.1 1.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG20271.1 - 2.7e-05 23.5 0.1 4.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG20271.1 - 8.1e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAG20271.1 - 0.00066 19.1 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG20271.1 - 0.0024 17.0 0.2 0.012 14.6 0.0 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Methyltransf_25 PF13649.6 OAG20272.1 - 1e-13 51.8 0.0 2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG20272.1 - 1.3e-12 48.2 0.0 2.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG20272.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG20272.1 - 8.1e-10 38.4 0.0 9.7e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG20272.1 - 6e-08 32.6 0.0 7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG20272.1 - 8.1e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG20272.1 - 0.00019 22.1 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAG20272.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 4HBT_3 PF13622.6 OAG20273.1 - 1.8e-25 90.7 0.7 2.6e-20 73.8 0.1 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG20273.1 - 5.4e-08 32.7 2.0 0.026 14.4 0.1 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase AA_permease_2 PF13520.6 OAG20274.1 - 7e-55 186.6 35.8 8.9e-55 186.2 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG20274.1 - 1.7e-22 79.7 39.0 2.6e-21 75.8 39.0 2.2 1 1 0 1 1 1 1 Amino acid permease Apolipoprotein PF01442.18 OAG20276.1 - 1.4e-05 25.1 8.4 0.0044 16.9 1.5 3.0 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 OAG20276.1 - 0.00026 20.7 0.4 0.00026 20.7 0.4 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4795) XH PF03469.14 OAG20276.1 - 0.01 15.7 9.1 0.2 11.5 0.0 4.3 2 1 3 5 5 5 0 XH domain DUF4320 PF14208.6 OAG20276.1 - 0.065 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) MHB PF16525.5 OAG20276.1 - 0.068 13.4 0.5 8.1 6.8 0.0 3.9 4 0 0 4 4 4 0 Haemophore, haem-binding Gp-FAR-1 PF05823.12 OAG20276.1 - 0.12 12.7 10.4 1.6 9.0 1.3 3.5 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.13 OAG20276.1 - 0.25 12.0 14.6 3.3 8.4 0.0 5.7 4 1 3 7 7 7 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.13 OAG20276.1 - 0.4 11.2 2.0 7.8 7.1 0.0 3.7 4 1 1 5 5 5 0 Histidine kinase Fib_alpha PF08702.10 OAG20276.1 - 0.41 10.8 5.1 0.62 10.3 0.5 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family RBD-FIP PF09457.10 OAG20276.1 - 0.52 10.3 2.0 26 4.8 0.1 3.5 2 1 1 3 3 3 0 FIP domain ApoLp-III PF07464.11 OAG20276.1 - 0.97 9.5 20.4 2.8 8.0 0.6 4.4 2 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Myb_DNA-bind_4 PF13837.6 OAG20276.1 - 1.3 9.5 4.6 2.3 8.7 1.0 2.8 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain ApoL PF05461.11 OAG20276.1 - 1.8 7.8 7.0 1.8 7.8 0.1 2.9 4 0 0 4 4 4 0 Apolipoprotein L CarD_CdnL_TRCF PF02559.16 OAG20276.1 - 2.4 8.9 9.9 3.5 8.4 1.7 4.2 2 1 1 4 4 4 0 CarD-like/TRCF domain DUF3235 PF11574.8 OAG20276.1 - 4.8 8.1 7.1 4.8 8.1 0.2 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF3235) Shadoo PF14999.6 OAG20276.1 - 5.6 7.1 9.9 12 6.0 9.9 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective FAM184 PF15665.5 OAG20276.1 - 7 6.4 13.0 4.1 7.1 0.1 3.5 2 1 0 3 3 3 0 Family with sequence similarity 184, A and B HAD_2 PF13419.6 OAG20277.1 - 9.6e-25 87.7 0.0 1.2e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG20277.1 - 1.2e-10 42.1 0.0 4.9e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG20277.1 - 1.9e-05 24.6 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG20277.1 - 0.0047 17.0 0.0 0.049 13.7 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG20277.1 - 0.014 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.17 OAG20279.1 - 3.9e-34 118.1 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG20279.1 - 1.5e-13 50.6 0.8 3.3e-13 49.5 0.8 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG20279.1 - 0.0002 21.1 0.1 0.0059 16.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Insulin_TMD PF17870.1 OAG20281.1 - 0.16 12.0 2.1 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Pyr_redox_2 PF07992.14 OAG20282.1 - 8.7e-15 54.7 0.0 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG20282.1 - 1.4e-14 54.1 0.0 1.4e-11 44.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG20282.1 - 7.3e-11 41.2 0.3 1.1e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG20282.1 - 4.3e-08 32.7 0.0 4.8e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 OAG20282.1 - 0.0046 16.3 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 OAG20282.1 - 0.009 16.2 0.0 0.035 14.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 OAG20282.1 - 0.01 16.1 0.0 0.72 10.1 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain SnoaL_2 PF12680.7 OAG20282.1 - 0.029 15.0 0.1 0.29 11.8 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain Shikimate_DH PF01488.20 OAG20282.1 - 0.031 14.3 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG20282.1 - 0.16 11.8 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 OAG20283.1 - 7e-30 103.9 0.0 9.1e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG20283.1 - 1.8e-17 63.7 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG20283.1 - 0.00026 20.9 0.1 0.00057 19.9 0.1 1.6 1 1 0 1 1 1 1 KR domain GMC_oxred_N PF00732.19 OAG20284.1 - 6.9e-66 222.6 0.0 9.7e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG20284.1 - 1.5e-38 132.5 0.1 3.1e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG20284.1 - 3.4e-07 29.7 0.3 0.017 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG20284.1 - 1.7e-06 27.9 0.9 0.00047 19.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG20284.1 - 1.1e-05 25.6 0.1 3e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG20284.1 - 4.4e-05 22.8 0.1 0.0001 21.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG20284.1 - 0.00016 21.0 0.1 0.075 12.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG20284.1 - 0.00076 18.6 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG20284.1 - 0.0018 17.0 0.4 0.03 13.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG20284.1 - 0.0053 16.0 0.4 0.038 13.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG20284.1 - 0.013 15.5 0.2 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG20284.1 - 0.024 14.9 0.4 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain AAA PF00004.29 OAG20285.1 - 7.8e-19 68.4 0.0 1.6e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG20285.1 - 5.8e-05 23.4 0.2 0.0019 18.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG20285.1 - 0.0013 19.2 0.2 0.0055 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAG20285.1 - 0.0018 18.8 0.2 0.014 15.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OAG20285.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.12 OAG20285.1 - 0.019 14.6 0.0 0.6 9.7 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 OAG20285.1 - 0.02 15.1 0.2 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG20285.1 - 0.056 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 OAG20285.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 OAG20285.1 - 0.079 13.3 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAG20285.1 - 0.11 11.9 1.8 0.16 11.3 0.3 1.9 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 OAG20285.1 - 0.15 11.4 0.2 0.33 10.3 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 OAG20289.1 - 2e-88 293.6 0.0 1.6e-44 151.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG20289.1 - 4.5e-18 64.8 0.8 1.3e-07 31.3 0.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG20289.1 - 1.6e-12 48.2 2.6 0.0023 18.3 0.1 5.0 3 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 OAG20289.1 - 5.7e-12 45.7 0.0 0.00018 21.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG20289.1 - 6.5e-11 42.7 1.8 0.026 14.8 0.1 5.6 2 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 OAG20289.1 - 2.4e-10 40.6 0.1 0.00087 19.3 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG20289.1 - 7.3e-09 35.9 0.0 0.0056 16.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 OAG20289.1 - 9.1e-09 35.7 0.0 0.0027 17.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAG20289.1 - 1.9e-08 33.9 0.6 0.0026 17.0 0.0 3.4 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 OAG20289.1 - 2.9e-07 30.6 0.0 0.045 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 OAG20289.1 - 3.5e-07 30.8 0.0 0.071 13.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_3 PF07726.11 OAG20289.1 - 8e-07 29.0 0.0 0.0063 16.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG20289.1 - 1.1e-06 28.9 0.0 0.085 13.2 0.0 2.8 2 1 0 2 2 2 2 RNA helicase Rad17 PF03215.15 OAG20289.1 - 1.2e-06 28.5 0.0 0.0069 16.3 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 OAG20289.1 - 1.4e-06 28.7 0.0 0.064 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 OAG20289.1 - 2e-06 27.8 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OAG20289.1 - 3e-06 26.7 0.1 0.066 12.5 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.21 OAG20289.1 - 6.6e-06 25.7 0.2 0.048 13.0 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAG20289.1 - 1.9e-05 24.5 0.0 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 OAG20289.1 - 6.3e-05 22.4 0.1 0.32 10.3 0.0 2.9 2 1 0 2 2 2 2 KaiC DUF815 PF05673.13 OAG20289.1 - 0.00011 21.4 0.0 0.039 13.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 OAG20289.1 - 0.00013 21.8 5.5 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 OAG20289.1 - 0.00014 21.8 0.3 1.1 9.2 0.1 3.5 3 0 0 3 3 3 2 NACHT domain ABC_tran PF00005.27 OAG20289.1 - 0.00016 22.2 0.0 0.14 12.7 0.0 3.1 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 OAG20289.1 - 0.00019 21.0 0.1 1.1 8.8 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 OAG20289.1 - 0.0002 21.8 4.4 0.48 10.9 0.0 4.3 5 0 0 5 5 4 2 AAA domain Sigma54_activat PF00158.26 OAG20289.1 - 0.00038 20.2 0.0 0.19 11.4 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain SKI PF01202.22 OAG20289.1 - 0.00056 20.1 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin2 PF13189.6 OAG20289.1 - 0.001 19.3 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 OAG20289.1 - 0.0023 17.2 0.0 2.5 7.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 OAG20289.1 - 0.0024 17.5 1.8 1.5 8.3 0.2 3.3 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OAG20289.1 - 0.0029 17.4 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAG20289.1 - 0.0036 16.8 0.1 0.73 9.3 0.1 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 OAG20289.1 - 0.004 16.9 0.0 0.97 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 OAG20289.1 - 0.0063 16.6 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAG20289.1 - 0.0075 16.2 0.0 4.9 7.0 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 OAG20289.1 - 0.0081 15.6 0.0 1.9 7.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AAA_19 PF13245.6 OAG20289.1 - 0.019 15.3 0.8 12 6.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain GP68 PF17469.2 OAG20289.1 - 0.02 15.3 0.0 0.083 13.3 0.0 2.1 1 1 1 2 2 1 0 Phage protein Gp68 ResIII PF04851.15 OAG20289.1 - 0.032 14.2 0.2 15 5.5 0.0 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit CPT PF07931.12 OAG20289.1 - 0.035 13.9 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF384 PF04064.13 OAG20289.1 - 0.079 12.8 0.1 0.36 10.7 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF384) AAA_30 PF13604.6 OAG20289.1 - 0.14 11.9 1.0 26 4.5 0.0 3.4 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 OAG20289.1 - 0.14 12.1 0.2 7.2 6.5 0.0 2.8 2 1 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 OAG20289.1 - 0.34 10.6 3.6 3.8 7.2 0.0 3.0 4 0 0 4 4 2 0 Cytidylate kinase DUF4519 PF15012.6 OAG20289.1 - 1.9 8.7 4.9 15 5.9 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) SURF2 PF05477.11 OAG20289.1 - 4 7.1 12.7 7.6 6.1 12.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Snf7 PF03357.21 OAG20290.1 - 5.5e-33 114.0 9.1 8.9e-33 113.3 9.1 1.3 1 0 0 1 1 1 1 Snf7 IL34 PF15036.6 OAG20290.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Interleukin 34 PFEMP PF03011.15 OAG20290.1 - 1.1 9.9 7.2 2.6 8.7 1.0 2.2 2 0 0 2 2 2 0 PFEMP DBL domain Ead_Ea22 PF13935.6 OAG20290.1 - 3.4 8.3 9.6 0.43 11.2 2.7 2.1 1 1 0 2 2 2 0 Ead/Ea22-like protein PITH PF06201.13 OAG20291.1 - 5.7e-42 143.5 0.0 7.1e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain LSM PF01423.22 OAG20292.1 - 9.9e-17 60.4 0.0 1.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain G6PD_bact PF10786.9 OAG20294.1 - 0.0056 16.3 0.5 0.007 15.9 0.5 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Spore_III_AB PF09548.10 OAG20294.1 - 0.2 11.8 0.0 0.45 10.6 0.0 1.6 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) MIP PF00230.20 OAG20295.1 - 3.4e-46 157.8 17.0 4.3e-46 157.4 17.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DPPIV_N PF00930.21 OAG20296.1 - 1.4e-102 343.1 3.2 1.9e-102 342.6 3.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAG20296.1 - 8.4e-39 133.2 0.1 1.5e-38 132.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG20296.1 - 2.6e-05 23.9 0.3 9.3e-05 22.1 0.1 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 OAG20296.1 - 0.014 16.0 0.0 0.091 13.3 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2920 PF11144.8 OAG20296.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PD40 PF07676.12 OAG20296.1 - 0.28 11.2 2.0 1.9 8.5 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TRL PF13146.6 OAG20297.1 - 0.029 14.6 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 TRL-like protein family Lipase_GDSL_2 PF13472.6 OAG20298.1 - 7.8e-05 23.1 0.0 0.00011 22.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG20298.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase NOGCT PF08155.11 OAG20298.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain UPF0242 PF06785.11 OAG20299.1 - 0.0018 18.4 12.4 0.0018 18.4 12.4 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OAG20299.1 - 0.019 15.4 12.4 0.019 15.4 12.4 3.2 2 1 1 3 3 3 0 Fez1 HlyE PF06109.13 OAG20299.1 - 0.23 10.7 3.0 0.51 9.6 0.9 2.3 2 0 0 2 2 2 0 Haemolysin E (HlyE) ApoO PF09769.9 OAG20299.1 - 0.36 10.8 4.4 18 5.3 0.2 4.0 4 1 0 4 4 4 0 Apolipoprotein O V_ATPase_I PF01496.19 OAG20299.1 - 0.53 8.1 11.7 0.17 9.8 4.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PKcGMP_CC PF16808.5 OAG20299.1 - 0.74 9.7 8.1 2.6 8.0 0.4 3.5 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GIT_CC PF16559.5 OAG20299.1 - 1.2 9.0 7.6 9.7 6.1 0.0 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 OAG20299.1 - 2.9 8.4 12.2 0.24 11.8 0.7 4.1 3 1 1 4 4 4 0 Snapin/Pallidin MARVEL PF01284.23 OAG20301.1 - 2.1e-20 73.2 24.9 2.6e-20 72.9 24.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain Sugar_tr PF00083.24 OAG20302.1 - 5.4e-80 269.5 27.2 6.2e-80 269.3 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG20302.1 - 7.8e-31 107.3 26.4 2.1e-27 96.0 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG20302.1 - 5.4e-05 21.9 21.5 6.9e-05 21.6 5.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein YrhK PF14145.6 OAG20302.1 - 0.15 12.0 8.1 0.088 12.7 0.6 3.4 3 0 0 3 3 3 0 YrhK-like protein BAT PF15915.5 OAG20303.1 - 0.047 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 GAF and HTH_10 associated domain DUF3512 PF12024.8 OAG20305.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Fringe PF02434.16 OAG20306.1 - 0.0001 21.9 0.0 0.00077 19.0 0.0 2.2 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 OAG20306.1 - 0.00041 20.2 3.7 0.00077 19.3 3.7 1.4 1 0 0 1 1 1 1 PAN domain Cmc1 PF08583.10 OAG20307.1 - 0.12 12.4 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GrpE PF01025.19 OAG20308.1 - 0.062 13.0 5.3 0.095 12.4 5.3 1.2 1 0 0 1 1 1 0 GrpE COG2 PF06148.11 OAG20308.1 - 0.098 12.7 1.0 0.17 12.0 1.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Glyco_transf_18 PF15024.6 OAG20308.1 - 0.11 11.0 1.0 0.16 10.5 1.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 DUF1657 PF07870.11 OAG20309.1 - 0.034 14.0 2.4 0.24 11.3 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1657) Clr5 PF14420.6 OAG20309.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain HTH_33 PF13592.6 OAG20309.1 - 0.11 12.1 0.6 0.47 10.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DHC_N1 PF08385.12 OAG20310.1 - 6.2e-128 427.9 5.9 6.2e-128 427.9 5.9 5.3 6 1 0 6 6 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OAG20310.1 - 3.3e-126 420.7 2.8 8e-126 419.4 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OAG20310.1 - 1.5e-116 389.8 8.4 1.5e-116 389.8 8.4 6.3 6 2 2 8 8 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OAG20310.1 - 8.1e-76 254.0 0.6 8.1e-76 254.0 0.6 3.8 3 1 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 OAG20310.1 - 1e-67 228.2 0.0 3.7e-66 223.1 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 OAG20310.1 - 1.9e-42 145.6 9.1 1.9e-42 145.6 9.1 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OAG20310.1 - 1.2e-41 142.2 0.1 6.7e-36 123.5 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 OAG20310.1 - 1.1e-30 106.5 0.0 1.6e-11 44.3 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 OAG20310.1 - 3.9e-30 104.8 0.0 1.2e-29 103.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OAG20310.1 - 3.6e-29 101.3 0.0 5.6e-27 94.2 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OAG20310.1 - 4e-19 69.0 0.3 2.1e-18 66.7 0.1 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OAG20310.1 - 2.6e-15 56.9 0.6 0.014 15.6 0.0 7.0 5 1 1 6 6 6 3 AAA domain AAA PF00004.29 OAG20310.1 - 2.7e-12 47.3 0.0 0.0035 17.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG20310.1 - 7.5e-11 42.7 5.7 1.7 9.0 0.0 9.0 9 0 0 9 9 6 2 AAA ATPase domain AAA_33 PF13671.6 OAG20310.1 - 1.6e-10 41.3 2.0 0.036 14.2 0.0 5.6 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 OAG20310.1 - 1.1e-08 35.7 0.3 0.18 12.4 0.0 5.3 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.18 OAG20310.1 - 7.8e-06 25.4 0.0 0.25 10.6 0.1 4.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family T2SSE PF00437.20 OAG20310.1 - 8.2e-06 25.1 0.0 0.028 13.5 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 OAG20310.1 - 4.8e-05 23.0 0.2 2.3 8.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 OAG20310.1 - 5.3e-05 23.4 0.0 0.00035 20.7 0.0 2.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 OAG20310.1 - 7.6e-05 22.2 1.3 0.66 9.3 0.1 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAG20310.1 - 0.00012 22.2 0.3 1.6 8.8 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 OAG20310.1 - 0.00045 20.0 0.4 5.7 6.6 0.0 5.1 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 OAG20310.1 - 0.0006 20.2 2.3 0.27 11.6 0.0 4.8 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 OAG20310.1 - 0.0012 18.6 0.5 0.55 9.9 0.0 4.5 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 OAG20310.1 - 0.0043 16.7 0.0 0.2 11.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG20310.1 - 0.013 16.0 9.9 5.6 7.5 0.0 5.9 6 0 0 6 6 4 0 ABC transporter RNA_helicase PF00910.22 OAG20310.1 - 0.019 15.3 0.1 43 4.6 0.0 4.4 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 OAG20310.1 - 0.024 14.5 0.4 5 7.0 0.0 4.0 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_21 PF13304.6 OAG20310.1 - 0.084 12.7 0.1 8.9 6.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 OAG20310.1 - 0.57 10.1 6.3 32 4.4 0.1 4.7 4 0 0 4 4 3 0 NACHT domain Ntox28 PF15605.6 OAG20310.1 - 7.5 6.9 9.8 1.3e+02 2.8 0.0 5.1 4 0 0 4 4 4 0 Bacterial toxin 28 Voltage_CLC PF00654.20 OAG20311.1 - 1.6e-88 297.3 25.8 1.6e-88 297.3 25.8 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG20311.1 - 1.1e-11 45.0 0.0 0.0002 21.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain LPAM_1 PF08139.12 OAG20311.1 - 2.1 9.0 5.2 5.3 7.7 0.0 2.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site GMP_synt_C PF00958.22 OAG20312.1 - 4.3e-43 145.3 0.0 9.5e-43 144.2 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAG20312.1 - 6.1e-39 133.8 0.0 9.4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAG20312.1 - 1e-11 44.4 0.2 1.5e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAG20312.1 - 1.5e-06 28.1 0.1 3.1e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 OAG20312.1 - 4.4e-05 23.1 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 OAG20312.1 - 0.00088 18.9 0.1 0.0074 15.9 0.1 2.1 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 OAG20312.1 - 0.0016 17.3 0.2 0.0082 15.0 0.1 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 OAG20312.1 - 0.016 14.5 0.1 0.059 12.7 0.1 1.8 2 0 0 2 2 2 0 Arginosuccinate synthase BCIP PF13862.6 OAG20313.1 - 1.2e-72 244.0 0.1 1.8e-72 243.5 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Rieske PF00355.26 OAG20314.1 - 1.2e-10 41.2 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 OAG20314.1 - 2.1e-09 37.7 0.5 7.3e-09 36.0 0.5 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.21 OAG20315.1 - 2.5e-18 66.3 0.0 3.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Macro domain CBFD_NFYB_HMF PF00808.23 OAG20316.1 - 3.7e-11 43.1 0.8 6.2e-11 42.4 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG20316.1 - 0.0043 17.4 0.7 0.0043 17.4 0.7 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2796 PF10986.8 OAG20316.1 - 0.041 13.8 0.3 0.064 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Peptidase_S10 PF00450.22 OAG20317.1 - 1.9e-97 327.4 0.0 2.3e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NYD-SP12_N PF15015.6 OAG20318.1 - 1.1 7.5 5.9 1.4 7.2 5.9 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Peptidase_C37 PF05416.12 OAG20318.1 - 6.5 5.1 12.7 7.1 5.0 12.7 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase adh_short PF00106.25 OAG20319.1 - 1.2e-53 181.5 0.0 1.7e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG20319.1 - 3e-35 121.9 0.0 3.6e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG20319.1 - 2.3e-12 47.2 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG20319.1 - 0.0011 18.2 0.1 0.0046 16.1 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG20319.1 - 0.015 15.6 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RsgA_GTPase PF03193.16 OAG20319.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF1776 PF08643.10 OAG20319.1 - 0.032 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CbiA PF01656.23 OAG20319.1 - 0.27 11.3 1.4 6.4 6.9 0.0 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_E3 PF06040.11 OAG20321.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein DUF883 PF05957.13 OAG20321.1 - 2 9.1 3.9 1.4 9.6 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TRI12 PF06609.13 OAG20322.1 - 2.3e-28 99.0 25.5 3.5e-28 98.4 25.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG20322.1 - 1.5e-22 80.0 37.3 1.5e-22 80.0 37.3 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20322.1 - 4.3e-08 32.5 7.5 4.3e-08 32.5 7.5 3.8 3 1 1 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 OAG20322.1 - 0.032 14.4 6.6 0.11 12.7 0.1 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 zf-C3HC4_3 PF13920.6 OAG20323.1 - 0.013 15.3 10.9 0.025 14.4 10.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG20323.1 - 0.022 14.6 5.9 0.022 14.6 5.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG20323.1 - 0.072 13.1 4.5 0.069 13.2 2.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAG20323.1 - 0.078 13.3 11.1 0.2 12.0 11.1 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OAG20323.1 - 0.36 10.7 12.7 3.9 7.4 12.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FAM193_C PF15914.5 OAG20323.1 - 0.51 10.1 3.8 1.8 8.3 3.8 1.9 1 0 0 1 1 1 0 FAM193 family C-terminal zf-RING_5 PF14634.6 OAG20323.1 - 0.84 9.6 13.1 3.7 7.6 13.2 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Fibrillin_U_N PF18193.1 OAG20323.1 - 1.1 9.4 5.4 11 6.3 0.3 2.7 3 0 0 3 3 3 0 Fibrillin 1 unique N-terminal domain zf-C3HC4 PF00097.25 OAG20323.1 - 1.2 9.1 12.1 2.7 7.9 12.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sulfate_transp PF00916.20 OAG20325.1 - 1.3e-99 333.6 18.8 1.7e-99 333.1 18.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG20325.1 - 3.4e-07 29.9 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain SpoIIIAC PF06686.11 OAG20325.1 - 1 9.6 4.5 0.57 10.4 0.4 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Hepatitis_core PF00906.20 OAG20326.1 - 0.39 10.2 7.1 0.6 9.6 7.1 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Fungal_trans PF04082.18 OAG20328.1 - 1.4e-21 76.7 0.0 2.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20328.1 - 4.5e-07 29.9 14.3 7.3e-07 29.2 14.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U3_snoRNA_assoc PF08297.11 OAG20328.1 - 0.036 14.8 0.0 0.097 13.4 0.0 1.7 1 0 0 1 1 1 0 U3 snoRNA associated Pox_A_type_inc PF04508.12 OAG20328.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Fungal_trans PF04082.18 OAG20329.1 - 5.4e-11 42.0 1.5 8.8e-11 41.3 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20329.1 - 7.5e-08 32.4 9.9 1.2e-07 31.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeodomain PF00046.29 OAG20330.1 - 1.4e-09 37.6 0.0 4.7e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OAG20330.1 - 2.6e-06 27.2 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_jaz PF12171.8 OAG20330.1 - 0.29 11.5 2.5 8.3 6.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG20330.1 - 0.29 11.6 5.1 4.1 7.9 0.0 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OAG20330.1 - 3.1 8.4 25.5 0.3 11.6 0.2 6.2 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF4202 PF13875.6 OAG20331.1 - 3.1e-81 271.7 0.4 3.5e-81 271.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) RRF PF01765.19 OAG20332.1 - 0.0081 16.1 0.5 0.0091 16.0 0.5 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF2575 PF10837.8 OAG20332.1 - 0.016 15.5 0.5 0.022 15.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Zip PF02535.22 OAG20332.1 - 0.1 11.8 0.9 0.11 11.6 0.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DLIC PF05783.11 OAG20332.1 - 0.11 11.4 2.7 0.13 11.1 2.7 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF5521 PF17659.1 OAG20332.1 - 0.78 7.5 3.2 0.8 7.5 3.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RIFIN PF02009.16 OAG20332.1 - 5.1 6.9 8.5 5.7 6.7 8.5 1.0 1 0 0 1 1 1 0 Rifin Asn_synthase PF00733.21 OAG20333.1 - 5.3e-16 59.2 0.9 4.6e-06 26.5 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 OAG20333.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain ACP PF06857.11 OAG20333.1 - 0.076 13.3 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) VPS9 PF02204.18 OAG20334.1 - 2.9e-27 94.9 0.0 4.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG20334.1 - 4.2e-15 55.8 0.1 1.7e-14 53.8 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 OAG20334.1 - 5.6e-09 35.5 0.0 9.6e-08 31.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain Alpha-amylase PF00128.24 OAG20336.1 - 2.5e-113 379.1 0.9 3.9e-113 378.4 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAG20336.1 - 3.9e-05 22.9 0.0 7.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 OAG20336.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain AA_permease PF00324.21 OAG20337.1 - 0.002 16.8 0.2 0.0039 15.8 0.2 1.4 1 0 0 1 1 1 1 Amino acid permease DUF4386 PF14329.6 OAG20337.1 - 0.21 11.4 5.8 0.94 9.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4386) PIG-Y PF15159.6 OAG20337.1 - 1 10.3 4.6 6.2 7.8 2.4 2.4 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y FAD_binding_4 PF01565.23 OAG20339.1 - 1.9e-22 79.5 0.9 3.1e-22 78.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG20340.1 - 1.8e-45 154.5 0.0 2.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG20340.1 - 8.4e-29 99.9 0.0 9.7e-29 99.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 OAG20340.1 - 0.0088 15.4 0.2 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 OAG20340.1 - 0.042 14.4 0.1 0.16 12.6 0.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 OAG20341.1 - 4.2e-45 154.9 0.6 4.9e-45 154.6 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG20341.1 - 0.0011 19.1 0.2 0.0011 19.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG20341.1 - 0.015 14.6 0.1 0.035 13.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAG20341.1 - 0.022 14.0 3.9 0.045 13.0 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Inhibitor_I42 PF09394.10 OAG20341.1 - 0.048 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 K_oxygenase PF13434.6 OAG20341.1 - 0.084 12.0 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG20341.1 - 0.14 12.1 0.6 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding CUE PF02845.16 OAG20342.1 - 1.7e-11 43.6 0.0 5.2e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 CUE domain VCPO_N PF17897.1 OAG20343.1 - 7.3e-109 362.6 2.3 1.1e-108 361.9 2.3 1.3 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 OAG20343.1 - 5.9e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.16 OAG20344.1 - 1.5e-38 132.6 53.3 2.9e-36 125.1 53.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20344.1 - 1.6e-09 37.1 20.3 1.6e-09 37.1 20.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter HhH-GPD PF00730.25 OAG20345.1 - 1.1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ATG22 PF11700.8 OAG20346.1 - 4.7e-171 569.6 8.4 5.3e-171 569.4 8.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG20346.1 - 2.2e-06 26.8 46.3 0.0031 16.5 6.4 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG20346.1 - 1.5e-05 23.8 7.9 1.5e-05 23.8 7.9 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein MFAP1 PF06991.11 OAG20347.1 - 6.6e-66 222.3 28.2 6.6e-66 222.3 28.2 2.4 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Cwf_Cwc_15 PF04889.12 OAG20347.1 - 0.15 11.7 45.5 0.016 15.0 25.8 2.9 1 1 2 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Y2_Tnp PF04986.13 OAG20347.1 - 0.94 9.5 4.4 0.99 9.4 0.6 2.2 2 0 0 2 2 2 0 Putative transposase Cyclin PF08613.11 OAG20348.1 - 2.4e-12 47.5 0.0 3.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG20348.1 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 OAG20353.1 - 2.3e-31 109.2 0.2 3.3e-31 108.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GDPD PF03009.17 OAG20356.1 - 1e-19 71.3 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ribonuc_L-PSP PF01042.21 OAG20358.1 - 7.9e-15 54.9 0.0 9.9e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Zn_clus PF00172.18 OAG20360.1 - 2.2e-07 30.9 8.0 4.1e-07 30.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG20360.1 - 0.009 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BST2 PF16716.5 OAG20360.1 - 0.31 11.6 0.1 0.31 11.6 0.1 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Fasciclin PF02469.22 OAG20361.1 - 2.9e-35 121.3 0.0 1.6e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain IDO PF01231.18 OAG20362.1 - 1.8e-39 135.7 0.0 3.5e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GTP_EFTU PF00009.27 OAG20362.1 - 5.8e-18 65.1 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAG20362.1 - 3.1e-09 37.1 2.3 1.3e-08 35.1 1.7 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OAG20362.1 - 0.00014 22.2 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAG20362.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG20362.1 - 0.14 12.0 0.4 6.7 6.6 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 OAG20362.1 - 0.2 11.4 1.1 2.5 7.9 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_ligase PF09414.10 OAG20363.1 - 6.4e-11 42.8 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Fmp27 PF10344.9 OAG20365.1 - 1.5e-216 721.5 0.0 2.3e-216 720.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 OAG20365.1 - 9.9e-183 608.4 8.0 9.9e-183 608.4 8.0 3.0 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 OAG20365.1 - 8.7e-171 569.0 0.1 8.7e-171 569.0 0.1 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 OAG20365.1 - 4.4e-59 199.1 0.0 9.6e-59 198.0 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAG20365.1 - 1.4e-57 193.9 0.6 3.1e-57 192.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 OAG20365.1 - 4.6e-31 107.6 0.0 2.3e-30 105.3 0.0 2.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CorA PF01544.18 OAG20365.1 - 0.26 10.6 4.0 0.89 8.8 1.3 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-C3HC4_3 PF13920.6 OAG20366.1 - 8.4e-08 32.0 11.2 8.4e-08 32.0 11.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG20366.1 - 1.9e-06 28.1 12.7 1.9e-06 28.1 12.7 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAG20366.1 - 2e-06 27.5 9.2 5.5e-06 26.1 9.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG20366.1 - 1.5e-05 24.8 11.9 1.5e-05 24.8 11.9 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG20366.1 - 2.5e-05 24.1 12.7 2.5e-05 24.1 12.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG20366.1 - 0.00038 20.4 6.1 0.00038 20.4 6.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG20366.1 - 0.0071 16.2 12.4 0.019 14.8 12.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG20366.1 - 0.0097 15.6 8.9 0.033 13.9 8.9 2.0 1 0 0 1 1 1 1 RING-like zinc finger BTB PF00651.31 OAG20367.1 - 2.7e-15 56.5 0.0 6.4e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain ADH_N PF08240.12 OAG20369.1 - 3.2e-25 88.1 4.4 5.1e-25 87.5 2.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG20369.1 - 2.5e-24 85.7 0.2 3.7e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20369.1 - 2.7e-07 31.7 0.0 5.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG20369.1 - 0.1 12.0 0.6 0.17 11.3 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F-box PF00646.33 OAG20370.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain Spy1 PF11357.8 OAG20371.1 - 0.038 14.3 0.1 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein FAD_binding_4 PF01565.23 OAG20372.1 - 8.9e-14 51.4 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_20 PF00728.22 OAG20373.1 - 1.5e-22 80.5 0.4 1.2e-19 71.0 0.4 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OAG20373.1 - 2.4e-08 34.8 0.0 5.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DIOX_N PF14226.6 OAG20374.1 - 2.4e-25 89.6 0.0 4.1e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG20374.1 - 9.4e-17 61.4 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_pol_B PF00136.21 OAG20376.1 - 2.5e-145 484.7 0.1 3.5e-145 484.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG20376.1 - 9.4e-82 274.8 0.2 1.5e-81 274.1 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAG20376.1 - 4.3e-18 65.5 8.2 1.2e-17 64.1 8.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAG20376.1 - 3.3e-05 23.7 0.1 7.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 OAG20376.1 - 0.00015 20.8 0.2 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 OAG20376.1 - 0.012 15.6 0.8 0.089 12.8 0.8 2.4 1 1 0 1 1 1 0 RNase_H superfamily HD_2 PF12917.7 OAG20376.1 - 0.016 15.0 0.5 0.053 13.3 0.1 2.2 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme DUF2614 PF11023.8 OAG20376.1 - 0.11 12.6 0.3 0.26 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon containing domain ETC_C1_NDUFA5 PF04716.14 OAG20376.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region C1_1 PF00130.22 OAG20376.1 - 0.5 10.3 10.3 0.57 10.1 1.0 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Amidohydro_2 PF04909.14 OAG20377.1 - 4.3e-28 98.9 0.0 7.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_10 PF13673.7 OAG20377.1 - 3.8e-07 30.1 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG20377.1 - 2.9e-06 27.6 0.0 8.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG20377.1 - 1.2e-05 25.5 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OAG20377.1 - 0.0016 18.5 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG20377.1 - 0.0021 18.2 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain TatD_DNase PF01026.21 OAG20377.1 - 0.0081 15.6 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 TatD related DNase Pyridoxal_deC PF00282.19 OAG20378.1 - 6.1e-119 397.1 0.0 8e-119 396.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 OAG20378.1 - 0.00043 19.6 0.1 0.0047 16.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Bystin PF05291.11 OAG20380.1 - 3.2e-125 417.2 0.0 4.3e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 Bystin NTP_transf_9 PF04248.12 OAG20381.1 - 1.2e-31 108.5 1.3 1.3e-31 108.3 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pyr_redox_2 PF07992.14 OAG20382.1 - 4.4e-51 173.9 0.0 5.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG20382.1 - 2.7e-11 43.8 0.0 7.3e-10 39.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG20382.1 - 0.0076 15.5 0.0 3.6 6.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DUF4172 PF13776.6 OAG20382.1 - 0.16 12.3 0.2 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) PQ-loop PF04193.14 OAG20383.1 - 9.5e-34 115.0 9.7 1.6e-18 66.2 2.3 2.3 2 0 0 2 2 2 2 PQ loop repeat DUF4395 PF14340.6 OAG20384.1 - 1.7 8.9 5.8 2.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF5597 PF18120.1 OAG20386.1 - 2.5e-25 89.1 0.0 4.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 OAG20386.1 - 2.4e-14 53.5 0.0 3.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 OAG20386.1 - 6.5e-11 42.4 0.0 4e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 OAG20386.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Zn_clus PF00172.18 OAG20387.1 - 2.2e-07 30.9 10.6 3.4e-07 30.3 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG20388.1 - 2.6e-87 293.6 18.5 2.9e-87 293.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG20388.1 - 4.9e-25 88.2 56.8 3.6e-22 78.8 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4731 PF15875.5 OAG20389.1 - 0.22 11.8 1.3 0.97 9.7 1.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Nodulin_late PF07127.11 OAG20389.1 - 0.32 11.4 0.0 0.32 11.4 0.0 2.6 3 0 0 3 3 3 0 Late nodulin protein WBP-1 PF11669.8 OAG20389.1 - 0.94 10.1 3.6 2.4 8.8 0.1 2.8 3 0 0 3 3 3 0 WW domain-binding protein 1 FAD_binding_4 PF01565.23 OAG20390.1 - 6.5e-25 87.5 0.1 1.2e-24 86.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG20390.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Kdo PF06293.14 OAG20391.1 - 7.8e-09 35.2 0.0 5.9e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG20391.1 - 2.2e-07 31.0 0.4 0.00023 21.2 0.2 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG20391.1 - 4.8e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OAG20391.1 - 0.0007 19.2 0.0 0.14 11.8 0.0 2.2 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 OAG20391.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OAG20391.1 - 0.0072 15.9 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAG20391.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Cu_bind_like PF02298.17 OAG20393.1 - 0.00027 20.9 0.5 0.0031 17.5 0.5 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.6 OAG20393.1 - 0.0061 16.6 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 OAG20393.1 - 0.037 14.5 1.8 0.18 12.2 1.8 2.1 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF5485 PF17586.2 OAG20393.1 - 0.36 11.2 1.5 1.5 9.2 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5485) DUF2014 PF09427.10 OAG20395.1 - 8.9e-110 366.2 8.3 8.9e-110 366.2 8.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2014) HLH PF00010.26 OAG20395.1 - 4e-17 61.9 0.6 1.1e-16 60.5 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAP65_ASE1 PF03999.12 OAG20395.1 - 0.09 11.5 7.5 0.16 10.6 7.5 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4298 PF14131.6 OAG20395.1 - 1.3 9.0 4.7 1.9 8.5 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) GATA PF00320.27 OAG20397.1 - 3.5e-15 55.3 5.3 6.3e-15 54.5 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 OAG20397.1 - 0.44 10.8 1.6 0.93 9.8 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon GCS PF03074.16 OAG20398.1 - 7.5e-176 584.9 0.0 9.1e-176 584.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Ank_2 PF12796.7 OAG20399.1 - 8.9e-41 138.4 9.5 1.7e-14 54.2 0.3 7.9 4 3 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG20399.1 - 2.9e-33 113.8 13.4 1.4e-09 38.3 0.0 9.5 7 2 2 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG20399.1 - 3.8e-29 97.5 15.2 0.0008 19.7 0.0 13.5 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 OAG20399.1 - 3.2e-21 74.7 19.3 0.00019 21.7 0.1 8.9 9 1 1 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OAG20399.1 - 8.2e-17 61.1 19.5 0.00041 20.6 0.4 10.2 6 5 6 12 12 12 4 Ankyrin repeats (many copies) Clr5 PF14420.6 OAG20399.1 - 3.5e-13 49.6 0.8 8.1e-13 48.4 0.8 1.7 1 0 0 1 1 1 1 Clr5 domain Imm49 PF15575.6 OAG20399.1 - 0.031 14.1 0.4 6.4 6.5 0.0 3.3 3 0 0 3 3 3 0 Immunity protein 49 Sulfotransfer_4 PF17784.1 OAG20400.1 - 1.2e-56 191.9 0.0 1.4e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG20400.1 - 1.8e-05 25.2 0.1 6.5e-05 23.4 0.0 1.9 1 1 2 3 3 3 1 Sulfotransferase family Tom22 PF04281.13 OAG20401.1 - 2.5e-45 153.7 2.3 2.8e-45 153.5 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Porin_3 PF01459.22 OAG20402.1 - 4.5e-79 265.7 0.0 5.2e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 OAG20403.1 - 1.2e-60 204.7 0.0 1.6e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG20403.1 - 1e-22 80.8 0.2 8.8e-22 77.7 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1771 PF08590.10 OAG20403.1 - 0.0053 17.1 0.3 0.41 11.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) AAA_33 PF13671.6 OAG20403.1 - 0.0063 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG20403.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zn_Tnp_IS1595 PF12760.7 OAG20405.1 - 0.26 11.3 2.0 31 4.6 0.6 2.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF1451 PF07295.11 OAG20405.1 - 2.1 8.4 6.7 1.5 8.9 1.9 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Abhydrolase_6 PF12697.7 OAG20407.1 - 2.2e-05 25.1 0.5 3.7e-05 24.4 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAG20407.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAG20407.1 - 0.0019 17.9 0.2 0.0037 17.0 0.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 OAG20407.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 OAG20407.1 - 0.031 13.4 0.1 0.052 12.7 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OAG20407.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase IL6 PF00489.17 OAG20407.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family ADH_N PF08240.12 OAG20409.1 - 8.9e-27 93.1 4.1 8.9e-27 93.1 4.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG20409.1 - 2.3e-14 53.5 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20409.1 - 0.00073 20.6 0.0 0.0015 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 OAG20409.1 - 0.0051 16.6 0.3 0.0097 15.7 0.3 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 OAG20409.1 - 0.14 11.5 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WYL_3 PF18488.1 OAG20409.1 - 0.16 12.4 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 WYL domain Pro_isomerase PF00160.21 OAG20410.1 - 9.7e-44 149.4 0.0 2e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 OAG20410.1 - 3.4e-05 23.3 0.9 0.0001 21.8 0.0 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 OAG20410.1 - 8.6e-05 22.6 0.2 0.0029 17.8 0.0 2.6 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 OAG20410.1 - 0.0087 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Egh16-like PF11327.8 OAG20411.1 - 1.1e-67 228.0 18.1 1.5e-67 227.6 18.1 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor CNOT11 PF10155.9 OAG20412.1 - 1.4e-07 31.7 0.0 5.3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Pmp3 PF01679.17 OAG20413.1 - 2.7e-25 88.3 7.7 3.1e-25 88.1 7.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.12 OAG20413.1 - 4.1 7.4 7.9 0.7 9.9 2.1 2.0 2 0 0 2 2 2 0 Conserved TM helix CsbD PF05532.12 OAG20414.1 - 9.3e-14 51.1 28.8 1.4e-07 31.3 10.0 3.2 2 1 1 3 3 3 3 CsbD-like IDO PF01231.18 OAG20415.1 - 1.7e-164 547.7 0.0 2e-164 547.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Clathrin_propel PF01394.20 OAG20415.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Clathrin propeller repeat Pex24p PF06398.11 OAG20416.1 - 1.6e-89 300.4 0.0 2e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 OAG20416.1 - 1.3 8.7 4.1 0.87 9.3 0.8 2.1 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Pkinase PF00069.25 OAG20417.1 - 6.9e-52 176.4 0.0 9.8e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20417.1 - 2.1e-17 63.2 0.2 5.2e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase MMR_HSR1_C PF08438.10 OAG20418.1 - 1.5e-36 125.4 0.0 2.7e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 OAG20418.1 - 1.8e-16 60.3 0.0 5.4e-16 58.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG20418.1 - 1.6e-05 24.4 0.0 0.00025 20.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG20418.1 - 0.0013 18.3 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG20418.1 - 0.0036 17.2 0.5 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OAG20418.1 - 0.018 15.5 0.1 0.76 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 OAG20418.1 - 0.048 13.7 0.7 0.15 12.1 0.2 2.0 2 0 0 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 OAG20418.1 - 0.088 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 OAG20418.1 - 0.093 12.9 0.1 6 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OAG20418.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1_Xtn PF16897.5 OAG20418.1 - 0.19 11.8 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 OAG20418.1 - 0.21 11.3 0.2 19 4.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Hemerythrin PF01814.23 OAG20419.1 - 2.5e-08 34.6 0.5 4e-08 33.9 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HET PF06985.11 OAG20420.1 - 8.8e-12 45.6 6.0 8.4e-10 39.2 1.2 3.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) STE2 PF02116.15 OAG20421.1 - 1.5e-86 290.2 23.1 1.8e-86 290.0 23.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF350 PF03994.14 OAG20421.1 - 0.071 13.3 0.0 0.071 13.3 0.0 3.1 3 1 0 3 3 3 0 Domain of Unknown Function (DUF350) BRCT PF00533.26 OAG20422.1 - 4.2e-06 27.0 0.2 2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG20422.1 - 0.019 14.9 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 OAG20422.1 - 0.097 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Spb1_C PF07780.12 OAG20423.1 - 9.2e-83 277.0 25.1 9.2e-83 277.0 25.1 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAG20423.1 - 5.1e-55 186.3 0.1 1e-54 185.3 0.1 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAG20423.1 - 1.5e-52 177.7 13.7 1.5e-52 177.7 13.7 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) YgaB PF14182.6 OAG20423.1 - 1.6 9.2 9.9 1.1 9.7 6.6 2.5 2 0 0 2 2 2 0 YgaB-like protein Cupin_8 PF13621.6 OAG20423.1 - 9.8 5.8 7.2 1.6 8.4 1.2 2.4 2 0 0 2 2 2 0 Cupin-like domain Rep_fac-A_3 PF08661.11 OAG20425.1 - 3.8e-29 101.1 0.0 4.3e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 HycH PF07450.11 OAG20425.1 - 0.082 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH OB_Dis3 PF17849.1 OAG20425.1 - 0.1 12.6 0.1 19 5.4 0.0 2.2 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) HATPase_c PF02518.26 OAG20426.1 - 6.5e-24 84.6 0.0 1.2e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG20426.1 - 1.6e-20 73.3 0.3 3.5e-20 72.3 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 OAG20426.1 - 4.6e-06 26.5 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OAG20426.1 - 0.0066 16.7 0.0 0.24 11.6 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG20426.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF4141 PF13605.6 OAG20426.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) PGAP1 PF07819.13 OAG20427.1 - 0.012 15.4 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein BAAT_C PF08840.11 OAG20427.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Malic_M PF03949.15 OAG20432.1 - 4.8e-94 314.4 0.0 7e-94 313.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAG20432.1 - 1.3e-66 223.9 0.0 1.8e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2345 PF10106.9 OAG20433.1 - 0.18 11.7 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) PRTase_3 PF15610.6 OAG20435.1 - 1.3e-93 313.1 0.8 1.4e-93 312.9 0.8 1.0 1 0 0 1 1 1 1 PRTase ComF-like DUF2244 PF10003.9 OAG20436.1 - 0.053 13.2 0.2 0.095 12.4 0.2 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) p450 PF00067.22 OAG20437.1 - 4.9e-40 137.7 0.0 9.3e-40 136.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 OAG20439.1 - 1.6e-73 247.5 0.0 2e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG20439.1 - 3.2e-10 40.1 0.0 7.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 OAG20440.1 - 4.3e-76 256.6 19.0 5e-76 256.4 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG20440.1 - 3.2e-23 82.2 25.8 8.2e-17 61.2 6.9 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily PTR2 PF00854.21 OAG20440.1 - 0.0081 15.0 2.0 0.017 13.9 2.0 1.5 1 0 0 1 1 1 1 POT family Peptidase_S28 PF05577.12 OAG20441.1 - 2.6e-48 164.9 0.2 9.1e-48 163.1 0.2 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 6PGD PF00393.19 OAG20443.1 - 1.7e-90 303.3 0.0 2.3e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG20443.1 - 4.6e-25 88.6 0.0 9.1e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG20443.1 - 1.1e-05 25.6 0.1 3.8e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 OAG20444.1 - 7.6e-17 60.9 0.1 1.2e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG20444.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_76 PF03663.14 OAG20445.1 - 5.4e-21 75.5 7.5 2.3e-13 50.4 1.2 4.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 Dscam_C PF12355.8 OAG20445.1 - 0.045 14.7 2.1 0.045 14.7 2.1 2.4 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal DUF3320 PF11784.8 OAG20445.1 - 0.15 12.0 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) IBN_N PF03810.19 OAG20446.1 - 7e-17 61.1 0.4 2.7e-16 59.2 0.2 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG20446.1 - 0.00088 19.3 0.6 0.0049 17.0 0.1 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Pex2_Pex12 PF04757.14 OAG20447.1 - 9e-36 123.6 1.9 1.4e-35 123.0 1.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 OAG20447.1 - 0.00021 21.4 4.4 0.0004 20.5 4.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG20447.1 - 0.02 14.9 2.3 0.071 13.2 2.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG20447.1 - 0.063 13.2 1.4 0.14 12.1 1.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG20447.1 - 3.3 7.6 9.2 3.2 7.7 5.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 OAG20448.1 - 1.6e-07 31.5 1.6 0.0035 18.1 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG20448.1 - 0.00011 22.5 2.8 0.0061 17.0 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 OAG20448.1 - 0.029 15.2 1.6 0.096 13.5 0.2 2.1 2 0 0 2 2 2 0 Ima1 N-terminal domain zf-Di19 PF05605.12 OAG20448.1 - 0.25 11.7 1.4 4.6 7.6 0.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_C12 PF01088.21 OAG20449.1 - 1.5e-51 175.1 0.0 1.8e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TRI12 PF06609.13 OAG20450.1 - 2.3e-71 241.0 21.4 3.1e-71 240.6 21.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG20450.1 - 1.9e-18 66.6 53.1 3.2e-17 62.5 49.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TMEM100 PF16311.5 OAG20450.1 - 0.036 13.7 2.7 0.3 10.7 0.0 2.9 3 0 0 3 3 3 0 Transmembrane protein 100 RNA_pol_Rpc34 PF05158.12 OAG20451.1 - 6.8e-75 252.5 0.1 3e-74 250.4 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HxlR PF01638.17 OAG20451.1 - 0.0026 17.6 0.1 0.0066 16.3 0.1 1.7 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_27 PF13463.6 OAG20451.1 - 0.004 17.6 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF3412 PF11892.8 OAG20451.1 - 0.0081 16.2 0.2 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3412) GntR PF00392.21 OAG20451.1 - 0.028 14.1 0.0 0.091 12.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 OAG20451.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 OAG20451.1 - 0.038 13.9 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 OAG20451.1 - 0.074 13.4 0.2 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator ANAPC2 PF08672.11 OAG20451.1 - 0.096 13.2 3.3 1.7 9.2 0.0 3.0 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 B-block_TFIIIC PF04182.12 OAG20451.1 - 0.13 12.5 0.1 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Methyltransf_25 PF13649.6 OAG20452.1 - 2.6e-13 50.5 0.0 5.9e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG20452.1 - 4.7e-11 43.2 0.0 9.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20452.1 - 1.1e-09 38.2 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG20452.1 - 3.7e-09 36.6 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG20452.1 - 6.6e-09 35.4 0.0 9.5e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG20452.1 - 1.7e-07 31.9 0.0 2.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG20452.1 - 0.0043 16.6 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG20452.1 - 0.031 13.7 0.0 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 OAG20452.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sipho_Gp157 PF05565.11 OAG20452.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Alk_phosphatase PF00245.20 OAG20453.1 - 4e-113 378.5 0.1 5.2e-113 378.1 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OAG20453.1 - 7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Zn_clus PF00172.18 OAG20455.1 - 0.016 15.3 10.2 0.026 14.6 10.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IZUMO PF15005.6 OAG20455.1 - 0.67 10.5 8.3 0.85 10.1 6.1 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Ribosomal_L34e PF01199.18 OAG20456.1 - 2.7e-43 146.2 3.3 3.7e-43 145.8 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PROCN PF08083.11 OAG20457.1 - 1.4e-234 778.2 8.8 1.4e-234 778.2 8.8 2.6 3 0 0 3 3 3 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAG20457.1 - 2.9e-126 419.7 1.0 5.4e-126 418.8 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAG20457.1 - 8.3e-89 295.6 2.3 2.9e-88 293.8 2.3 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAG20457.1 - 1.1e-77 259.2 1.3 1.1e-77 259.2 1.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAG20457.1 - 6.9e-71 236.6 0.1 1.4e-70 235.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 OAG20457.1 - 6.5e-48 161.7 0.0 2.4e-47 159.9 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 OAG20457.1 - 5.6e-47 158.0 0.9 1.9e-46 156.3 0.9 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF536 PF04394.14 OAG20457.1 - 0.067 13.1 4.3 0.24 11.3 4.3 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF536 p450 PF00067.22 OAG20458.1 - 3.9e-58 197.3 0.0 5.1e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 OAG20459.1 - 0.0035 17.2 0.1 0.0035 17.2 0.1 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG20459.1 - 0.027 14.4 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 F-box-like 2-Hacid_dh_C PF02826.19 OAG20460.1 - 2.6e-42 144.2 0.0 4.4e-42 143.4 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG20460.1 - 3e-08 33.4 0.0 4.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG20460.1 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG20460.1 - 0.01 16.4 0.1 0.028 15.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 OAG20461.1 - 9.6e-16 57.6 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20461.1 - 1.5e-09 37.8 12.3 1.5e-09 37.8 12.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPA_interact_N PF14766.6 OAG20461.1 - 0.023 14.4 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Hist_deacetyl PF00850.19 OAG20462.1 - 1.4e-76 257.9 0.0 1.9e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 OAG20463.1 - 5.4e-23 81.5 2.4 1e-22 80.6 2.4 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAG20463.1 - 1e-05 25.3 9.4 1.6e-05 24.7 9.4 1.3 1 0 0 1 1 1 1 PHD-finger LRRFIP PF09738.9 OAG20463.1 - 0.017 14.6 0.4 0.017 14.6 0.4 1.6 2 0 0 2 2 2 0 LRRFIP family PHD_2 PF13831.6 OAG20463.1 - 0.017 14.7 2.5 0.028 14.0 2.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OAG20463.1 - 0.018 15.3 0.2 0.037 14.3 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PKcGMP_CC PF16808.5 OAG20463.1 - 0.037 13.9 1.0 0.09 12.6 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAT PF03127.14 OAG20463.1 - 0.05 13.9 0.2 0.05 13.9 0.2 1.8 2 0 0 2 2 2 0 GAT domain Filament PF00038.21 OAG20463.1 - 2.3 7.7 8.1 0.12 11.9 1.7 1.8 2 0 0 2 2 2 0 Intermediate filament protein zf-RING_4 PF14570.6 OAG20463.1 - 8 6.3 9.8 0.89 9.4 3.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GIT_SHD PF08518.11 OAG20464.1 - 2e-22 78.5 6.9 2.7e-12 46.1 0.4 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT CENP-F_leu_zip PF10473.9 OAG20464.1 - 0.0034 17.4 27.4 0.04 13.9 9.5 2.8 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 OAG20464.1 - 0.0039 17.2 21.1 0.0039 17.2 21.1 2.5 1 1 2 3 3 3 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 OAG20464.1 - 0.0062 16.2 7.1 0.0062 16.2 7.1 3.2 2 1 0 3 3 3 1 Intermediate filament protein Myosin_tail_1 PF01576.19 OAG20464.1 - 0.012 13.5 30.6 0.15 9.8 22.0 2.1 1 1 1 2 2 2 0 Myosin tail BLOC1_2 PF10046.9 OAG20464.1 - 0.018 15.3 16.9 0.16 12.2 3.7 4.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIP1_clath_bdg PF16515.5 OAG20464.1 - 0.042 14.5 23.8 0.6 10.8 7.7 3.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SHE3 PF17078.5 OAG20464.1 - 0.048 13.4 19.5 0.028 14.1 2.7 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Lectin_N PF03954.14 OAG20464.1 - 0.21 11.4 12.3 6.3 6.6 4.5 3.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.9 OAG20464.1 - 0.27 11.4 33.9 1 9.5 7.4 3.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 OAG20464.1 - 0.43 10.6 13.0 13 5.8 0.0 4.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 OAG20464.1 - 0.54 10.4 24.0 0.51 10.5 1.0 4.0 3 1 0 3 3 3 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 OAG20464.1 - 0.88 9.8 22.9 1.9 8.7 1.7 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.8 OAG20464.1 - 1.2 7.9 7.2 0.096 11.5 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) SlyX PF04102.12 OAG20464.1 - 1.3 9.7 21.7 3 8.5 5.6 4.7 3 1 0 3 3 3 0 SlyX ZapB PF06005.12 OAG20464.1 - 1.8 9.0 33.7 1.1 9.8 0.6 4.4 1 1 2 3 3 2 0 Cell division protein ZapB DUF1572 PF07609.11 OAG20464.1 - 2 8.2 5.3 1.1 9.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1572) Tropomyosin PF00261.20 OAG20464.1 - 2.3 7.5 31.9 0.081 12.3 12.5 3.7 1 1 1 3 3 3 0 Tropomyosin CLZ PF16526.5 OAG20464.1 - 3.7 8.0 21.7 0.7 10.3 1.6 5.0 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 OAG20464.1 - 4.9 5.9 36.3 1.6 7.6 11.9 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 OAG20464.1 - 5.3 7.2 38.2 4.4 7.5 25.4 2.8 2 1 1 3 3 2 0 Tropomyosin like bZIP_1 PF00170.21 OAG20464.1 - 5.3 7.2 22.4 0.1 12.7 3.1 4.3 3 1 1 4 4 4 0 bZIP transcription factor DUF4407 PF14362.6 OAG20464.1 - 6.1 6.1 29.2 0.073 12.4 10.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) BST2 PF16716.5 OAG20464.1 - 6.3 7.4 25.0 3.7 8.2 1.6 3.6 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 YtxH PF12732.7 OAG20464.1 - 9.3 6.9 12.8 44 4.7 3.3 4.3 4 1 0 4 4 3 0 YtxH-like protein DUF1664 PF07889.12 OAG20464.1 - 9.4 6.3 20.5 0.85 9.7 2.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Glyco_hydro_43 PF04616.14 OAG20465.1 - 3.3e-29 102.1 0.4 4.2e-29 101.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5348 PF17295.2 OAG20465.1 - 0.15 12.0 0.4 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) Beta-lactamase PF00144.24 OAG20466.1 - 1.4e-67 228.4 0.0 1.7e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase PUCC PF03209.15 OAG20466.1 - 0.08 11.9 0.6 0.12 11.4 0.6 1.2 1 0 0 1 1 1 0 PUCC protein Zn_clus PF00172.18 OAG20467.1 - 2.6e-09 37.1 7.3 5.6e-09 36.0 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG20467.1 - 0.00019 20.4 2.7 0.00029 19.8 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAG20468.1 - 1.7e-62 210.7 19.1 2.1e-62 210.4 19.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Tautomerase_3 PF14832.6 OAG20468.1 - 0.015 15.5 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme DUF4208 PF13907.6 OAG20470.1 - 7.8e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DUF498 PF04430.14 OAG20471.1 - 8.7e-29 99.8 0.0 1.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) E3_binding PF02817.17 OAG20471.1 - 0.053 13.9 0.2 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 e3 binding domain p450 PF00067.22 OAG20474.1 - 8.3e-73 245.7 0.0 1.1e-72 245.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAG20474.1 - 6.4e-22 78.2 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG20474.1 - 2.4e-18 66.7 0.0 5.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG20474.1 - 1.1e-11 45.4 0.0 9.8e-11 42.3 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG20474.1 - 0.0058 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 OAG20474.1 - 0.0087 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Glyco_hydr_116N PF12215.8 OAG20474.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Rax2 PF12768.7 OAG20476.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity AA_permease PF00324.21 OAG20477.1 - 3.8e-09 35.7 6.3 4.8e-09 35.3 6.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG20477.1 - 4.2e-08 32.5 11.3 4.7e-08 32.3 11.3 1.0 1 0 0 1 1 1 1 Amino acid permease Tachykinin PF02202.16 OAG20477.1 - 0.095 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Tachykinin family AA_permease_2 PF13520.6 OAG20478.1 - 2.3e-44 151.9 30.0 2.7e-44 151.7 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG20478.1 - 1.5e-14 53.5 20.9 1.8e-14 53.2 20.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4064 PF13273.6 OAG20478.1 - 0.074 13.3 0.3 0.074 13.3 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Pho86 PF11124.8 OAG20478.1 - 0.26 10.7 2.6 0.5 9.8 2.6 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Methyltransf_25 PF13649.6 OAG20480.1 - 3.3e-08 34.1 0.0 7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20480.1 - 1.7e-06 27.9 0.1 1.4e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG20480.1 - 1.8e-06 27.9 0.2 3.5e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OAG20480.1 - 1.3e-05 24.6 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG20480.1 - 0.00012 22.7 0.0 0.00034 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG20480.1 - 0.00035 20.4 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG20480.1 - 0.0047 16.5 0.0 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 OAG20480.1 - 0.0064 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 OAG20480.1 - 0.0086 16.8 0.0 0.036 14.8 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG20480.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 OAG20480.1 - 0.037 15.0 0.0 0.075 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RNase_P_p30 PF01876.16 OAG20480.1 - 0.041 13.3 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 RNase P subunit p30 Fibrillarin PF01269.17 OAG20480.1 - 0.059 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin GCD14 PF08704.10 OAG20480.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 OAG20480.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 OAG20480.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Fungal_trans PF04082.18 OAG20482.1 - 1.3e-16 60.4 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20482.1 - 1.4e-09 37.9 6.6 2.7e-09 37.0 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAG20483.1 - 9.4e-07 28.4 4.9 0.0086 15.4 0.3 3.1 2 1 1 3 3 3 3 FAD binding domain MAPEG PF01124.18 OAG20486.1 - 1.2e-21 77.0 0.1 1.3e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Glyco_hydro_115 PF15979.5 OAG20488.1 - 7.2e-101 338.0 0.1 6.1e-72 242.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 115 GH115_C PF17829.1 OAG20488.1 - 7.5e-48 162.6 0.0 1.3e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain NTPase_P4 PF11602.8 OAG20488.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Glyco_hydro_92 PF07971.12 OAG20489.1 - 1.1e-126 423.6 0.5 2.6e-126 422.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG20489.1 - 3.2e-42 145.1 1.7 5.2e-42 144.4 1.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain PAN_4 PF14295.6 OAG20490.1 - 3.4e-12 46.1 17.4 5e-06 26.3 1.1 4.4 4 0 0 4 4 4 2 PAN domain PAN_1 PF00024.26 OAG20490.1 - 2.4e-09 37.0 21.9 0.00013 21.9 0.4 4.1 4 1 0 4 4 4 3 PAN domain PAN_3 PF08277.12 OAG20490.1 - 0.00011 22.0 10.8 0.0093 15.8 0.2 3.9 3 1 0 3 3 3 2 PAN-like domain PAN_2 PF08276.11 OAG20490.1 - 0.0027 17.8 15.9 0.037 14.2 0.9 3.6 3 0 0 3 3 3 2 PAN-like domain SOG2 PF10428.9 OAG20490.1 - 0.9 8.7 11.1 1.2 8.2 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Trypan_PARP PF05887.11 OAG20490.1 - 2.4 8.1 19.2 0.031 14.3 10.5 2.2 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.13 OAG20490.1 - 3.9 6.4 14.6 3.2 6.6 0.1 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region UbiA PF01040.18 OAG20491.1 - 0.032 13.5 2.9 0.043 13.1 2.9 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family N2227 PF07942.12 OAG20492.1 - 4.7e-56 190.0 0.0 7.1e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 OAG20492.1 - 1.2e-05 25.8 0.2 7.2e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG20492.1 - 0.00011 22.9 0.3 0.00044 20.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG20492.1 - 0.00012 22.0 0.1 0.00043 20.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG20492.1 - 0.0007 20.3 0.4 0.023 15.4 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20492.1 - 0.017 14.9 0.4 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain DUF2804 PF10974.8 OAG20493.1 - 0.057 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) p450 PF00067.22 OAG20494.1 - 1.1e-70 238.6 0.0 1.3e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M41 PF01434.18 OAG20495.1 - 2.4e-56 190.6 0.1 3.9e-56 189.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAG20495.1 - 7.2e-43 146.2 0.0 1.8e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG20495.1 - 6.7e-09 35.4 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG20495.1 - 1.1e-05 25.4 0.0 4.9e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG20495.1 - 5.9e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAG20495.1 - 0.00012 22.5 1.3 0.0011 19.4 0.7 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG20495.1 - 0.00045 20.5 0.0 0.17 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG20495.1 - 0.00089 18.9 0.6 0.43 10.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG20495.1 - 0.0046 16.7 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAG20495.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG20495.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 OAG20495.1 - 0.029 13.7 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 OAG20495.1 - 0.037 13.4 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 OAG20495.1 - 0.056 13.6 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 OAG20495.1 - 0.14 11.7 0.0 0.55 9.7 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region UCR_hinge PF02320.16 OAG20496.1 - 6.3e-25 87.2 9.7 1e-24 86.5 9.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein RraA-like PF03737.15 OAG20496.1 - 6.8e-23 81.5 0.5 9.9e-23 81.0 0.5 1.2 1 0 0 1 1 1 1 Aldolase/RraA UPF0731 PF14982.6 OAG20496.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 UPF0731 family UDPG_MGDP_dh_N PF03721.14 OAG20496.1 - 0.086 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zip PF02535.22 OAG20496.1 - 0.27 10.4 2.7 0.39 9.9 2.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OAG20496.1 - 2.9 6.1 4.8 6.5 4.9 5.0 1.4 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.16 OAG20497.1 - 3.6e-22 78.8 38.0 3.6e-22 78.8 38.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 OAG20498.1 - 1.9e-35 122.3 2.0 3.7e-35 121.4 2.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 OAG20498.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) YlaC PF10777.9 OAG20500.1 - 0.31 10.9 0.8 0.4 10.5 0.8 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC NmrA PF05368.13 OAG20501.1 - 8.6e-50 169.5 0.8 1e-49 169.2 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG20501.1 - 3.5e-15 56.4 0.1 4.9e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG20501.1 - 2.5e-05 23.4 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG20501.1 - 9.5e-05 22.7 0.1 0.00019 21.7 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG20501.1 - 0.00055 19.5 0.1 0.0008 18.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG20501.1 - 0.01 16.2 0.1 0.024 15.1 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PhzC-PhzF PF02567.16 OAG20501.1 - 0.043 13.3 0.2 0.067 12.6 0.2 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein NmrA PF05368.13 OAG20502.1 - 2e-13 50.5 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG20502.1 - 1.5e-11 44.6 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG20502.1 - 1.3e-05 24.8 0.2 0.00011 21.8 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG20502.1 - 0.00012 22.0 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG20502.1 - 0.0012 19.1 0.2 0.0035 17.6 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 OAG20502.1 - 0.011 15.6 0.1 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 LpxI N-terminal domain NAD_binding_4 PF07993.12 OAG20502.1 - 0.021 14.0 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.18 OAG20502.1 - 0.038 14.2 0.0 0.075 13.3 0.0 1.5 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 OAG20502.1 - 0.093 13.3 0.3 0.36 11.4 0.2 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 OAG20502.1 - 0.11 12.6 1.7 0.52 10.4 1.7 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 OAG20502.1 - 0.13 12.4 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-CCCH PF00642.24 OAG20503.1 - 0.0044 16.9 4.9 0.0044 16.9 4.9 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Malate_DH PF12434.8 OAG20503.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Cutinase PF01083.22 OAG20504.1 - 5e-24 85.2 0.2 6.6e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG20504.1 - 1e-09 38.3 0.0 3.2e-09 36.7 0.1 1.7 1 1 1 2 2 2 1 PE-PPE domain Thioesterase PF00975.20 OAG20504.1 - 2.5e-05 24.5 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain VirJ PF06057.11 OAG20504.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF726 PF05277.12 OAG20504.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Palm_thioest PF02089.15 OAG20504.1 - 0.11 12.4 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PHINT_rpt PF14882.6 OAG20505.1 - 0.056 13.7 2.1 4.8 7.5 0.0 3.5 3 0 0 3 3 3 0 Phage-integrase repeat unit CorA PF01544.18 OAG20506.1 - 2.7e-11 43.4 1.1 2.7e-11 43.4 1.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein 7TM-7TMR_HD PF07698.11 OAG20506.1 - 0.053 13.3 1.0 0.087 12.6 1.0 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF4404 PF14357.6 OAG20506.1 - 0.099 13.3 1.7 27 5.5 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Glyoxalase_3 PF13468.6 OAG20508.1 - 4.9e-27 95.2 0.0 3.1e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase-like domain Fungal_trans PF04082.18 OAG20509.1 - 3.7e-14 52.4 0.6 6.6e-14 51.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20509.1 - 1.9e-06 27.9 14.1 3.1e-06 27.2 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_cobalt PF09819.9 OAG20510.1 - 0.05 13.7 0.4 0.06 13.5 0.4 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component Peptidase_M24 PF00557.24 OAG20511.1 - 7.8e-53 179.3 0.0 1.3e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG20511.1 - 2.5e-34 117.6 0.0 5.2e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SIR2 PF02146.17 OAG20512.1 - 3.9e-39 134.4 0.0 1.6e-38 132.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OAG20512.1 - 0.12 12.1 0.1 0.58 9.9 0.0 2.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain HET PF06985.11 OAG20515.1 - 3.9e-30 105.1 0.1 7.1e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-synt_A PF00119.20 OAG20516.1 - 0.072 13.0 0.9 2 8.3 0.5 2.0 1 1 1 2 2 2 0 ATP synthase A chain BetaGal_dom3 PF13363.6 OAG20516.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Beta-galactosidase, domain 3 AltA1 PF16541.5 OAG20517.1 - 0.0041 18.0 0.1 0.0053 17.6 0.1 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 HECT PF00632.25 OAG20518.1 - 4.4e-83 279.3 0.0 7.5e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OAG20518.1 - 0.00046 19.7 0.3 0.002 17.7 0.3 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zip PF02535.22 OAG20519.1 - 0.041 13.1 3.1 2.4 7.3 3.0 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter Fungal_trans_2 PF11951.8 OAG20520.1 - 3.9e-19 68.7 2.5 7.2e-19 67.9 2.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG20520.1 - 9.3e-07 28.9 12.3 1.7e-06 28.1 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG20521.1 - 1.6e-51 175.1 0.0 1.9e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20521.1 - 1.6e-38 132.1 0.2 2.6e-38 131.5 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG20521.1 - 2.4e-11 43.9 0.6 3.2e-11 43.5 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG20521.1 - 0.0099 15.4 0.1 0.017 14.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG20521.1 - 0.031 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.21 OAG20521.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF805 PF05656.14 OAG20521.1 - 0.18 12.2 0.0 0.25 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MFS_1 PF07690.16 OAG20522.1 - 4.7e-39 134.3 46.1 2.8e-22 79.1 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG20522.1 - 8.8e-06 24.5 13.5 8.8e-06 24.5 13.5 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein CitMHS PF03600.16 OAG20522.1 - 1.8 7.7 20.8 9.5 5.3 20.7 2.1 1 1 1 2 2 2 0 Citrate transporter Beta-lactamase PF00144.24 OAG20523.1 - 4.5e-61 206.9 0.0 5.8e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Uso1_p115_head PF04869.14 OAG20524.1 - 1.1e-104 349.9 0.0 3e-104 348.5 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAG20524.1 - 9.7e-14 51.8 65.6 9.7e-14 51.8 65.6 6.1 1 1 4 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 OAG20524.1 - 2e-05 24.7 16.6 2e-05 24.7 16.6 5.5 2 1 3 5 5 5 2 Afadin- and alpha -actinin-Binding HEAT_EZ PF13513.6 OAG20524.1 - 0.072 13.6 0.4 25 5.5 0.0 3.7 2 0 0 2 2 2 0 HEAT-like repeat DUF3800 PF12686.7 OAG20524.1 - 0.1 13.2 3.0 2.5 8.7 2.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Arm PF00514.23 OAG20524.1 - 5.7 7.1 10.0 0.91 9.7 0.0 4.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat NACHT PF05729.12 OAG20525.1 - 1.6e-06 28.1 0.0 3.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG20525.1 - 2.2e-05 24.9 0.4 0.00021 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG20525.1 - 0.0029 17.9 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAG20525.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Clc-like PF07062.12 OAG20525.1 - 0.15 11.5 0.2 0.83 9.1 0.2 2.0 2 0 0 2 2 2 0 Clc-like NAD_binding_1 PF00175.21 OAG20526.1 - 2.6e-11 44.1 0.0 4.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAG20526.1 - 8.1e-10 39.2 0.1 1.6e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Globin FAD_binding_8 PF08022.12 OAG20526.1 - 0.0058 16.7 0.0 0.018 15.1 0.0 2.0 1 0 0 1 1 1 1 FAD-binding domain Protoglobin PF11563.8 OAG20526.1 - 0.0072 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 OAG20526.1 - 0.0091 16.1 0.4 0.68 10.0 0.1 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain RNA_pol_Rpb2_2 PF04561.14 OAG20526.1 - 0.044 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 zf-C2H2 PF00096.26 OAG20527.1 - 8.8e-22 76.3 25.4 3.6e-05 24.0 1.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG20527.1 - 2.4e-18 65.7 25.4 1.7e-06 28.2 1.2 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG20527.1 - 4.5e-12 45.7 22.7 0.0042 17.8 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG20527.1 - 9.8e-07 28.9 0.1 2.3 8.6 0.0 4.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OAG20527.1 - 0.0023 17.7 9.2 0.02 14.6 0.8 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 OAG20527.1 - 0.0096 15.5 1.7 1.2 8.8 0.2 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 OAG20527.1 - 0.019 15.3 13.3 1.8 9.1 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG20527.1 - 0.55 10.2 6.9 17 5.4 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 OAG20527.1 - 0.8 9.9 8.5 2.8 8.2 0.9 3.2 1 1 3 4 4 4 0 Zinc ribbon domain DUF4764 PF15961.5 OAG20527.1 - 1 8.0 7.4 0.32 9.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) DZR PF12773.7 OAG20527.1 - 1.2 9.2 8.2 85 3.3 8.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.11 OAG20527.1 - 3.1 7.8 4.9 6.2 6.8 0.1 3.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 OAG20527.1 - 5.8 7.1 8.2 22 5.2 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Ogr_Delta PF04606.12 OAG20527.1 - 6.9 6.7 9.4 13 5.9 0.5 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 OAG20527.1 - 7.3 7.3 8.5 14 6.4 0.3 3.2 3 1 1 4 4 3 0 FOXP coiled-coil domain ENTH PF01417.20 OAG20528.1 - 9.6e-46 154.9 0.0 1.5e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAG20528.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 OAG20528.1 - 0.0048 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.20 OAG20528.1 - 0.063 13.2 6.9 0.5 10.4 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif bZIP_2 PF07716.15 OAG20529.1 - 2.6e-05 24.2 6.0 3.9e-05 23.6 6.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG20529.1 - 0.0017 18.4 5.1 0.0026 17.8 5.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor G-alpha PF00503.20 OAG20530.1 - 3.6e-47 161.2 2.1 4.2e-47 161.0 1.1 1.6 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 OAG20530.1 - 0.017 14.6 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 OAG20530.1 - 0.025 14.3 0.1 0.051 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain KELK PF15796.5 OAG20530.1 - 0.05 14.0 3.5 0.2 12.1 3.5 2.0 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3510 PF12022.8 OAG20530.1 - 0.13 12.6 1.6 0.58 10.5 1.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Flagellin_C PF00700.21 OAG20530.1 - 3.3 8.1 6.5 18 5.8 0.0 3.6 4 0 0 4 4 4 0 Bacterial flagellin C-terminal helical region F-box-like PF12937.7 OAG20531.1 - 1.6e-07 31.1 0.2 4e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG20531.1 - 0.011 15.6 0.5 0.024 14.5 0.5 1.5 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAG20531.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box HET PF06985.11 OAG20532.1 - 5.1e-26 91.8 0.4 8.3e-26 91.1 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG20533.1 - 4.7e-05 23.8 0.0 8.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1275 PF06912.11 OAG20535.1 - 0.038 13.9 8.4 0.21 11.5 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Tyrosinase PF00264.20 OAG20536.1 - 8.5e-41 140.7 2.8 1.4e-40 139.9 2.8 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase DAO PF01266.24 OAG20537.1 - 3.1e-26 92.8 0.0 6.6e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG20537.1 - 5.3e-06 26.5 0.0 0.091 12.8 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG20537.1 - 3.3e-05 23.3 0.0 0.015 14.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG20537.1 - 7.9e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG20537.1 - 0.019 14.1 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAG20537.1 - 0.023 14.0 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAG20537.1 - 0.12 11.5 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ras PF00071.22 OAG20539.1 - 9.9e-28 96.8 0.0 2.8e-27 95.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG20539.1 - 2.9e-05 24.2 0.0 0.00021 21.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Tyrosinase PF00264.20 OAG20540.1 - 4.9e-36 125.1 0.2 7.3e-36 124.5 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1949 PF09186.11 OAG20540.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) PAP1 PF08601.10 OAG20544.1 - 3.9e-123 411.9 23.3 3.9e-123 411.9 23.3 2.9 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 OAG20544.1 - 6.3e-09 35.8 10.5 1.2e-08 34.9 10.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 OAG20544.1 - 0.041 14.5 0.6 0.086 13.5 0.6 1.5 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.15 OAG20544.1 - 0.042 13.9 14.5 0.11 12.5 13.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 OAG20544.1 - 0.14 12.7 11.8 0.29 11.7 11.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SHE3 PF17078.5 OAG20544.1 - 0.14 11.8 6.3 0.28 10.8 6.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HAUS-augmin3 PF14932.6 OAG20544.1 - 0.15 11.6 4.2 0.27 10.8 4.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nop53 PF07767.11 OAG20544.1 - 0.24 10.7 12.5 0.41 10.0 12.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SPICE PF15678.5 OAG20544.1 - 2 7.7 12.5 0.11 11.8 1.9 2.2 2 0 0 2 2 2 0 Centriole duplication and mitotic chromosome congression Agenet PF05641.12 OAG20545.1 - 0.0024 18.3 0.1 0.0064 16.9 0.1 1.7 1 0 0 1 1 1 1 Agenet domain TUDOR PF00567.24 OAG20545.1 - 0.026 14.5 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Tudor domain Tudor_2 PF18104.1 OAG20545.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Herpes_US12 PF05363.12 OAG20545.1 - 0.28 11.9 3.3 1.2 9.9 0.6 2.6 2 0 0 2 2 2 0 Herpesvirus US12 family UCH_1 PF13423.6 OAG20546.1 - 3.7e-100 335.6 1.5 3.8e-100 335.6 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAG20546.1 - 2.2e-17 64.1 0.0 4.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 OAG20546.1 - 0.00025 20.6 0.0 0.0028 17.2 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 OAG20546.1 - 0.0055 17.0 0.0 1.4 9.3 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4945 PF16303.5 OAG20546.1 - 0.031 14.2 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Ima1_N PF09779.9 OAG20546.1 - 0.038 14.8 0.4 0.098 13.5 0.4 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain eIF2A PF08662.11 OAG20546.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A HD PF01966.22 OAG20547.1 - 5.2e-07 29.9 0.0 7.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 HD domain Pectate_lyase PF03211.13 OAG20548.1 - 1.4e-67 227.2 4.5 1.7e-67 226.9 4.5 1.0 1 0 0 1 1 1 1 Pectate lyase HET PF06985.11 OAG20550.1 - 5.5e-25 88.4 6.9 5.5e-25 88.4 6.9 2.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2390 PF09523.10 OAG20550.1 - 0.36 11.2 5.2 0.74 10.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) HET PF06985.11 OAG20551.1 - 3.5e-31 108.5 2.3 5.6e-31 107.9 2.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IL32 PF15225.6 OAG20551.1 - 0.035 14.5 1.1 13 6.2 0.3 2.8 1 1 1 2 2 2 0 Interleukin 32 Pkinase PF00069.25 OAG20553.1 - 8e-17 61.5 0.0 8.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20553.1 - 0.0005 19.4 0.0 0.0015 17.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Tannase PF07519.11 OAG20554.1 - 1.9e-109 366.7 0.0 2.6e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG20554.1 - 0.015 14.6 0.0 0.057 12.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2415 PF10313.9 OAG20555.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) CH PF00307.31 OAG20556.1 - 1.1e-12 48.1 0.0 2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Pox_A_type_inc PF04508.12 OAG20556.1 - 0.00072 19.3 3.8 0.00072 19.3 3.8 3.2 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat CAMSAP_CH PF11971.8 OAG20556.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 OAG20557.1 - 9.1e-11 42.5 0.7 9.1e-11 42.5 0.7 2.2 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3960 PF13142.6 OAG20558.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) Peroxidase_2 PF01328.17 OAG20559.1 - 2e-50 171.9 0.0 2.8e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 AIRC PF00731.20 OAG20559.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 AIR carboxylase PHINT_rpt PF14882.6 OAG20559.1 - 0.16 12.3 0.5 0.29 11.4 0.5 1.4 1 0 0 1 1 1 0 Phage-integrase repeat unit IPPT PF01715.17 OAG20561.1 - 2.9e-29 102.5 0.1 2.1e-13 50.6 0.0 2.1 1 1 1 2 2 2 2 IPP transferase IPT PF01745.16 OAG20561.1 - 5.2e-10 39.1 0.0 6.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 OAG20561.1 - 0.00014 22.5 0.0 0.00061 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAG20561.1 - 0.001 19.5 0.5 0.0048 17.3 0.5 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG20561.1 - 0.0024 18.1 0.0 0.0073 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAG20561.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein SKI PF01202.22 OAG20561.1 - 0.028 14.6 0.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_22 PF13401.6 OAG20561.1 - 0.034 14.4 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG20561.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OAG20561.1 - 0.091 13.3 0.5 0.23 12.0 0.4 2.1 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 OAG20561.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG20561.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MarR_2 PF12802.7 OAG20561.1 - 0.17 11.8 0.0 0.88 9.5 0.0 2.0 2 0 0 2 2 2 0 MarR family AAA_23 PF13476.6 OAG20561.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lysine_decarbox PF03641.14 OAG20562.1 - 2.1e-33 115.2 0.2 2.7e-33 114.8 0.2 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAG20562.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 SLOG cluster4 family HET PF06985.11 OAG20563.1 - 2e-30 106.0 0.5 4.9e-30 104.8 0.5 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RteC PF09357.10 OAG20564.1 - 0.022 14.5 1.6 0.039 13.6 1.6 1.3 1 0 0 1 1 1 0 RteC protein DUF3336 PF11815.8 OAG20564.1 - 0.12 12.1 1.8 4.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) HET PF06985.11 OAG20566.1 - 3.4e-09 37.2 0.1 4e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPMT PF05724.11 OAG20568.1 - 1.3e-30 106.7 0.0 9.6e-27 94.1 0.0 2.1 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OAG20568.1 - 2.4e-08 34.0 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG20568.1 - 2.7e-05 24.7 0.0 0.0001 22.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG20568.1 - 5.3e-05 23.9 0.0 8.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG20568.1 - 0.00018 22.2 0.0 0.0012 19.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20568.1 - 0.0005 19.9 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OAG20568.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.13 OAG20568.1 - 0.033 14.5 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Na_Ca_ex PF01699.24 OAG20569.1 - 2.4e-46 157.5 35.6 1.7e-23 83.2 16.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3185 PF11381.8 OAG20569.1 - 0.00026 20.9 0.5 0.66 10.0 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3185) Glyco_hydro81C PF17652.1 OAG20570.1 - 5.4e-108 361.3 3.5 7.6e-108 360.9 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAG20570.1 - 6.2e-100 334.5 0.0 8.1e-100 334.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Endonuclease_1 PF04231.13 OAG20570.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Endonuclease I Utp14 PF04615.13 OAG20571.1 - 9.2e-204 679.2 83.6 9.2e-204 679.2 83.6 2.3 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 OAG20572.1 - 9e-12 44.8 0.1 1.2e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Methyltransf_23 PF13489.6 OAG20573.1 - 6.6e-20 71.6 0.0 8.7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG20573.1 - 4.2e-17 62.6 0.0 6.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG20573.1 - 3.1e-13 50.2 0.0 4.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20573.1 - 4.5e-13 49.3 0.0 5.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG20573.1 - 5.2e-13 49.6 0.0 7.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG20573.1 - 7.6e-07 28.4 0.0 1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAG20573.1 - 5.2e-06 26.1 0.0 7.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG20573.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 OAG20573.1 - 0.045 13.0 0.0 0.28 10.4 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NAD_binding_8 PF13450.6 OAG20574.1 - 0.0027 17.9 0.0 0.007 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG20574.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DNA_pol3_a_NII PF11490.8 OAG20575.1 - 0.068 13.1 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Tox-REase-7 PF15649.6 OAG20575.1 - 0.072 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 UL17 PF17640.2 OAG20576.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized UL17 CRA_rpt PF07046.11 OAG20576.1 - 0.07 13.3 0.4 0.15 12.2 0.4 1.5 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Abhydrolase_1 PF00561.20 OAG20577.1 - 1.1e-15 58.0 0.1 3.5e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG20577.1 - 1.7e-14 55.0 0.0 3.1e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG20577.1 - 0.00023 20.5 0.0 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG20577.1 - 0.00067 18.8 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 OAG20577.1 - 0.017 14.1 0.0 0.078 11.9 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Ank_3 PF13606.6 OAG20578.1 - 0.0051 17.2 0.0 4.3 8.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OAG20578.1 - 0.0055 17.3 0.0 0.0081 16.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG20578.1 - 0.013 15.9 0.0 0.14 12.7 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 OAG20578.1 - 0.014 15.7 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG20578.1 - 0.024 15.2 0.0 6.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TetR_C_12 PF16914.5 OAG20578.1 - 0.062 13.4 0.0 0.23 11.6 0.0 1.8 1 1 1 2 2 2 0 Bacterial transcriptional repressor C-terminal DUF5365 PF17326.2 OAG20578.1 - 0.098 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Phage_T7_Capsid PF05396.11 OAG20578.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 1 1 2 2 2 0 Phage T7 capsid assembly protein CDC37_C PF08564.10 OAG20578.1 - 0.16 12.1 0.0 17 5.6 0.0 2.1 1 1 1 2 2 2 0 Cdc37 C terminal domain Ank_5 PF13857.6 OAG20579.1 - 0.00032 20.9 0.0 0.00052 20.2 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG20579.1 - 0.00047 20.4 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OAG20579.1 - 0.00061 20.3 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG20579.1 - 0.002 18.6 0.1 0.021 15.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG20579.1 - 0.021 15.3 0.1 7.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DUF5386 PF17360.2 OAG20579.1 - 0.057 13.3 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5386) Fungal_lectin_2 PF18647.1 OAG20580.1 - 0.15 12.5 4.2 1.5 9.3 0.1 3.1 3 1 0 3 3 3 0 Alpha-galactosyl-binding fungal lectin DUF3176 PF11374.8 OAG20581.1 - 6.1e-32 110.0 1.7 6.1e-32 110.0 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) zinc_ribbon_2 PF13240.6 OAG20582.1 - 0.0077 15.9 0.7 0.024 14.4 0.7 1.8 1 0 0 1 1 1 1 zinc-ribbon domain SURF4 PF02077.15 OAG20582.1 - 0.032 13.8 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 SURF4 family NuA4 PF09340.10 OAG20582.1 - 0.12 12.3 0.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Ribonuc_L-PSP PF01042.21 OAG20583.1 - 1.2e-20 73.8 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-U1 PF06220.12 OAG20584.1 - 9.4e-22 76.5 3.5 1.3e-21 76.1 3.5 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin_micro PF17003.5 OAG20584.1 - 0.14 11.3 0.1 0.16 11.1 0.1 1.0 1 0 0 1 1 1 0 Putative actin-like family NmrA PF05368.13 OAG20585.1 - 2.6e-09 37.0 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG20585.1 - 2.3e-08 34.2 0.0 1.8e-07 31.3 0.0 2.3 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG20585.1 - 3.7e-06 27.2 0.0 1.5e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG20585.1 - 2.3e-05 24.5 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 OAG20585.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus WD40 PF00400.32 OAG20586.1 - 9e-45 149.8 25.9 1.4e-08 35.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG20586.1 - 3.9e-09 36.7 0.3 0.055 13.8 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG20586.1 - 0.00018 20.3 4.9 0.18 10.4 0.1 4.3 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG20586.1 - 0.0019 17.2 0.0 9.8 5.0 0.0 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAG20586.1 - 0.017 14.5 0.0 1.2 8.4 0.0 2.5 2 1 2 4 4 4 0 WD40-like domain PD40 PF07676.12 OAG20586.1 - 0.026 14.5 0.9 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ECH_1 PF00378.20 OAG20587.1 - 6.8e-40 137.0 0.0 2e-39 135.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG20587.1 - 7.8e-28 97.9 0.0 8.9e-27 94.5 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase p450 PF00067.22 OAG20589.1 - 8.2e-46 156.7 0.0 1.1e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tyrosinase PF00264.20 OAG20590.1 - 1.1e-36 127.2 0.1 1.8e-36 126.5 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.7 OAG20591.1 - 0.00026 20.8 0.1 0.0006 19.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like FTH PF01827.27 OAG20591.1 - 0.14 11.9 0.2 14 5.5 0.0 2.6 2 1 0 2 2 2 0 FTH domain AMP-binding PF00501.28 OAG20592.1 - 2.3e-68 230.8 0.0 3.3e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG20592.1 - 5.8e-63 213.1 0.0 3.1e-37 128.3 0.0 2.6 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 OAG20592.1 - 6.6e-43 144.9 4.3 6.8e-15 55.2 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site DNA_ligase_A_N PF04675.14 OAG20592.1 - 0.092 13.1 0.1 0.42 10.9 0.0 2.1 2 1 0 2 2 2 0 DNA ligase N terminus Acetyltransf_1 PF00583.25 OAG20593.1 - 3.3e-10 40.2 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG20593.1 - 1e-09 38.4 0.1 5.6e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG20593.1 - 3.9e-08 33.6 0.1 9e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG20593.1 - 0.013 15.5 0.3 0.063 13.4 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG20593.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SAM_PNT PF02198.16 OAG20593.1 - 0.029 14.3 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Globin PF00042.22 OAG20593.1 - 0.036 14.6 0.4 0.38 11.3 0.1 2.1 2 0 0 2 2 2 0 Globin ABC_membrane PF00664.23 OAG20594.1 - 6e-85 285.2 16.2 4.4e-45 154.5 0.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG20594.1 - 5.1e-68 227.9 0.0 1e-32 113.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG20594.1 - 5.9e-14 52.0 1.3 0.00019 21.0 0.8 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG20594.1 - 2.9e-08 34.3 3.8 0.0093 16.4 1.7 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG20594.1 - 5.1e-08 33.3 0.9 0.057 13.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OAG20594.1 - 1.1e-06 27.7 2.8 0.0021 16.9 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAG20594.1 - 3.1e-06 26.8 2.9 0.022 14.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 OAG20594.1 - 4.6e-06 26.5 2.4 0.12 12.1 0.0 4.2 4 1 1 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 OAG20594.1 - 1.7e-05 24.8 0.2 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 OAG20594.1 - 5.1e-05 22.9 1.0 1.1 8.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAG20594.1 - 6.7e-05 23.4 0.0 0.57 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG20594.1 - 8.7e-05 22.5 1.3 0.13 12.0 0.0 3.0 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG20594.1 - 0.00018 21.4 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OAG20594.1 - 0.0008 19.6 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 OAG20594.1 - 0.0012 18.7 0.1 0.09 12.7 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF87 PF01935.17 OAG20594.1 - 0.0017 18.5 0.1 0.39 10.8 0.0 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_24 PF13479.6 OAG20594.1 - 0.0028 17.4 0.0 2 8.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG20594.1 - 0.003 18.1 0.4 3 8.3 0.3 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG20594.1 - 0.0032 16.8 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin SRP54 PF00448.22 OAG20594.1 - 0.005 16.5 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DNA_pol3_beta PF00712.19 OAG20594.1 - 0.008 16.3 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III beta subunit, N-terminal domain AAA_17 PF13207.6 OAG20594.1 - 0.0094 16.4 0.0 4.6 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG20594.1 - 0.014 15.4 0.0 12 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OAG20594.1 - 0.025 14.5 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 OAG20594.1 - 0.026 14.7 4.1 3.5 7.9 0.2 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 OAG20594.1 - 0.033 13.9 0.7 8.1 6.1 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 OAG20594.1 - 0.051 13.6 0.3 16 5.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 OAG20594.1 - 0.063 12.3 0.5 7.7 5.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 OAG20594.1 - 0.12 11.8 0.1 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 OAG20594.1 - 0.17 11.0 0.1 7.4 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain K_oxygenase PF13434.6 OAG20595.1 - 3e-54 184.5 0.0 1e-53 182.7 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG20595.1 - 0.038 14.0 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Acetyltransf_8 PF13523.6 OAG20596.1 - 6.1e-40 136.2 1.9 9.3e-40 135.7 1.9 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 OAG20597.1 - 4.1e-100 335.3 0.0 5e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG20597.1 - 1.2e-12 48.7 0.2 2.6e-12 47.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAO PF01266.24 OAG20598.1 - 7.5e-38 131.0 0.2 1e-37 130.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 OAG20598.1 - 8.8e-09 35.2 0.1 2.9e-08 33.6 0.0 1.8 2 0 0 2 2 1 1 Rieske [2Fe-2S] domain Thi4 PF01946.17 OAG20598.1 - 2.3e-06 27.0 0.1 4.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG20598.1 - 3.3e-06 27.2 0.8 7.4e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG20598.1 - 2.9e-05 23.3 0.3 4.6e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAG20598.1 - 4.4e-05 22.9 0.2 6.6e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG20598.1 - 0.0003 20.3 1.3 0.0026 17.2 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG20598.1 - 0.00041 19.5 0.3 0.006 15.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG20598.1 - 0.00049 19.4 1.1 0.00087 18.6 0.1 1.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG20598.1 - 0.00078 18.8 0.1 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG20598.1 - 0.013 14.6 0.6 0.027 13.6 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG20598.1 - 0.028 14.4 0.1 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG20598.1 - 0.055 14.0 0.6 0.055 14.0 0.6 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG20598.1 - 0.11 11.2 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 OAG20598.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG20598.1 - 0.14 12.1 0.3 0.25 11.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAG20600.1 - 5.9e-28 97.8 19.6 5.9e-28 97.8 19.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20600.1 - 5.8e-10 38.6 21.3 5.4e-07 28.8 4.7 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG20600.1 - 0.00048 18.5 0.6 0.00048 18.5 0.6 3.3 2 1 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 OAG20600.1 - 0.0015 17.1 1.3 0.003 16.0 1.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 OAG20600.1 - 0.0078 14.5 0.1 1.3 7.2 0.0 2.3 2 0 0 2 2 2 2 BT1 family VIT1 PF01988.19 OAG20600.1 - 0.011 15.6 0.7 6 6.7 0.2 2.7 2 1 0 2 2 2 0 VIT family PUCC PF03209.15 OAG20600.1 - 0.017 14.1 0.1 0.017 14.1 0.1 2.2 3 0 0 3 3 3 0 PUCC protein Iron_permease PF04120.12 OAG20600.1 - 0.23 11.2 2.3 14 5.4 0.2 2.9 2 0 0 2 2 2 0 Low affinity iron permease F-box PF00646.33 OAG20601.1 - 0.0033 17.3 0.0 0.0099 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG20601.1 - 0.0042 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 OAG20601.1 - 0.0085 16.0 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Glyco_transf_7N PF13733.6 OAG20601.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 PRANC PF09372.10 OAG20601.1 - 0.15 12.4 0.0 2.9 8.3 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Myosin_head PF00063.21 OAG20601.1 - 0.33 9.1 0.0 0.48 8.6 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) DNA_pol_phi PF04931.13 OAG20601.1 - 10 4.1 8.9 14 3.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 OAG20603.1 - 4.4e-08 32.4 68.9 6.9e-08 31.8 21.0 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1189 PF06691.11 OAG20603.1 - 6.9e-05 22.5 1.1 0.00021 20.9 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1189) Astacin PF01400.24 OAG20604.1 - 0.022 14.4 0.2 1.7 8.2 0.2 2.8 3 1 0 3 3 3 0 Astacin (Peptidase family M12A) Glyco_hydro_12 PF01670.16 OAG20605.1 - 2.1e-36 126.0 10.0 2.4e-36 125.7 10.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Peptidase_M4_C PF02868.15 OAG20606.1 - 5.9e-45 153.1 0.0 8.6e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 OAG20606.1 - 3e-15 57.0 0.0 7.9e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 OAG20606.1 - 0.00069 19.3 0.1 0.0026 17.4 0.1 2.0 1 1 0 1 1 1 1 Protealysin propeptide Peptidase_M57 PF12388.8 OAG20607.1 - 0.00066 19.3 0.3 0.0011 18.6 0.0 1.5 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 OAG20607.1 - 0.0016 17.4 0.1 0.011 14.7 0.2 1.9 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_5 PF13688.6 OAG20607.1 - 0.0032 17.6 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAG20607.1 - 0.0077 16.7 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAG20607.1 - 0.032 14.1 0.9 0.062 13.1 0.9 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 OAG20607.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OAG20607.1 - 0.056 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 OAG20607.1 - 0.17 11.5 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Pkinase PF00069.25 OAG20608.1 - 1.6e-39 135.8 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20608.1 - 4.9e-25 88.3 0.0 6.3e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAG20608.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OAG20608.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG20608.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG20608.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aa_trans PF01490.18 OAG20611.1 - 4.9e-53 180.3 36.7 5.5e-53 180.1 36.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspanin PF00335.20 OAG20611.1 - 0.29 10.8 0.1 0.29 10.8 0.1 3.3 3 1 0 3 3 3 0 Tetraspanin family His_Phos_1 PF00300.22 OAG20612.1 - 9.4e-18 64.6 0.1 3.9e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 OAG20613.1 - 2.3e-29 103.1 0.0 2.8e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG20613.1 - 2.5e-07 29.9 3.1 0.0014 17.6 0.1 3.0 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG20613.1 - 3.7e-07 30.3 0.5 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG20613.1 - 6.2e-05 22.4 0.1 0.00049 19.4 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG20613.1 - 0.00028 21.1 0.0 0.0014 18.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAG20613.1 - 0.00056 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 OAG20613.1 - 0.00095 18.3 0.0 0.0089 15.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 OAG20613.1 - 0.0078 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG20613.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG20613.1 - 0.035 13.3 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 OAG20613.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAG20613.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_C14 PF00656.22 OAG20615.1 - 2e-09 37.8 0.1 0.0021 18.0 0.0 2.5 2 1 0 2 2 2 2 Caspase domain Peptidase_C13 PF01650.18 OAG20615.1 - 0.037 13.6 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C13 family IFRD PF05004.13 OAG20615.1 - 0.05 12.7 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Raptor_N PF14538.6 OAG20615.1 - 0.072 13.0 2.9 2.6 8.0 0.3 3.5 3 1 0 3 3 3 0 Raptor N-terminal CASPase like domain ADH_zinc_N PF00107.26 OAG20616.1 - 7e-25 87.5 0.0 4.4e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG20616.1 - 1.1e-21 78.3 0.0 3.9e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG20616.1 - 0.00025 20.9 0.0 0.00056 19.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG20616.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 OAG20616.1 - 0.029 13.7 0.2 0.047 13.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mito_fiss_reg PF05308.11 OAG20620.1 - 0.048 13.8 2.3 0.085 12.9 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Helo_like_N PF17111.5 OAG20621.1 - 7e-05 22.3 0.6 9.5e-05 21.9 0.6 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MukF_M PF17192.4 OAG20621.1 - 0.0043 16.8 0.5 0.006 16.3 0.2 1.5 1 1 0 1 1 1 1 MukF middle domain AAA_13 PF13166.6 OAG20621.1 - 0.017 13.8 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 OAG20621.1 - 0.05 13.6 0.3 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF3450 PF11932.8 OAG20621.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF717 PF05338.12 OAG20621.1 - 0.099 12.8 0.1 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF717) NmrA PF05368.13 OAG20622.1 - 1.7e-13 50.7 0.0 2.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG20622.1 - 0.011 15.7 0.2 0.036 14.0 0.0 2.0 2 1 0 2 2 2 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG20622.1 - 0.023 15.1 0.0 0.089 13.2 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAG20622.1 - 0.091 12.7 0.6 4.3 7.2 0.0 2.7 2 1 0 3 3 3 0 KR domain RPT PF13446.6 OAG20625.1 - 0.013 15.4 0.1 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 A repeated domain in UCH-protein RdgC PF04381.12 OAG20625.1 - 0.055 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease, RdgC HET PF06985.11 OAG20626.1 - 2.4e-32 112.3 0.1 4.8e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stn1 PF10451.9 OAG20627.1 - 2.3e-12 46.4 0.4 5.5e-12 45.2 0.4 1.6 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 OAG20627.1 - 0.00012 22.0 1.9 0.0037 17.2 1.9 2.4 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain SHS2_Rpb7-N PF03876.17 OAG20627.1 - 0.08 13.3 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AAA_11 PF13086.6 OAG20627.1 - 0.64 9.7 9.5 2.5 7.8 9.5 1.8 1 1 0 1 1 1 0 AAA domain Granulin PF00396.18 OAG20628.1 - 0.0078 16.5 14.8 0.012 16.0 4.5 2.4 1 1 1 2 2 2 2 Granulin PfaD_N PF18328.1 OAG20628.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain Herpes_TAF50 PF03326.13 OAG20628.1 - 1.1 7.8 7.8 1.3 7.6 7.8 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) SnoaL_2 PF12680.7 OAG20629.1 - 0.0019 18.8 0.0 0.0026 18.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 OAG20629.1 - 0.086 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Inv-AAD PF18785.1 OAG20631.1 - 6e-61 204.0 0.2 7e-61 203.8 0.2 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAG20631.1 - 2.3e-15 56.3 0.0 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAG20631.1 - 0.0015 18.5 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 OAG20631.1 - 0.004 16.9 0.0 0.0071 16.1 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAG20631.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase DnaJ PF00226.31 OAG20632.1 - 1.1e-23 83.1 1.4 3.8e-23 81.4 1.4 2.0 1 0 0 1 1 1 1 DnaJ domain PEP_mutase PF13714.6 OAG20634.1 - 3.4e-63 213.3 0.6 3.9e-63 213.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Acetyltransf_3 PF13302.7 OAG20635.1 - 1.6e-15 58.0 0.0 2.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG20635.1 - 7e-05 23.0 0.0 9.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family APH PF01636.23 OAG20636.1 - 1.5e-11 44.7 0.3 3.6e-07 30.4 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG20636.1 - 0.002 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG20636.1 - 0.024 13.5 0.0 0.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 OAG20636.1 - 0.1 12.0 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 OAG20636.1 - 0.1 12.2 0.1 4.4 6.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Extensin_2 PF04554.13 OAG20638.1 - 2.3 8.4 43.6 5.1 7.2 14.6 2.3 1 1 1 2 2 2 0 Extensin-like region DUF1295 PF06966.12 OAG20639.1 - 7.5e-41 140.2 0.4 4e-39 134.5 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAG20639.1 - 0.0052 17.2 0.1 0.024 15.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 OAG20639.1 - 0.0075 16.3 0.1 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAG20639.1 - 0.012 16.1 0.0 0.045 14.2 0.0 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PsaM PF07465.13 OAG20639.1 - 1 9.1 4.9 2.5 7.9 0.7 2.6 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Sec3_C PF09763.9 OAG20640.1 - 3.1e-213 710.1 0.0 3.9e-213 709.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAG20640.1 - 5.5e-27 93.7 0.0 1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAG20640.1 - 0.00072 18.4 0.5 0.0014 17.4 0.5 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 OAG20640.1 - 0.0029 17.9 1.2 0.0068 16.7 1.2 1.6 1 0 0 1 1 1 1 Sec3 exocyst complex subunit HrpF PF06266.12 OAG20640.1 - 0.13 12.5 0.6 2 8.8 0.3 2.6 2 0 0 2 2 2 0 HrpF protein Sec34 PF04136.15 OAG20640.1 - 0.3 11.0 1.0 0.74 9.7 1.0 1.7 1 0 0 1 1 1 0 Sec34-like family SRP40_C PF05022.12 OAG20641.1 - 6.7e-21 74.9 1.5 6.7e-21 74.9 1.5 3.0 4 0 0 4 4 4 1 SRP40, C-terminal domain Complex1_LYR_2 PF13233.6 OAG20642.1 - 1.9e-20 73.4 0.9 2.2e-20 73.2 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like SAT PF16073.5 OAG20642.1 - 0.0048 16.7 0.6 0.0056 16.4 0.6 1.1 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DivIVA PF05103.13 OAG20642.1 - 0.048 13.7 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 DivIVA protein MMR_HSR1 PF01926.23 OAG20643.1 - 9.3e-16 57.9 0.1 1.8e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG20643.1 - 4.2e-06 26.9 0.1 0.0064 16.6 0.1 2.6 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 OAG20643.1 - 6e-05 22.6 0.0 0.024 14.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG20643.1 - 0.00032 20.3 0.0 0.0007 19.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG20643.1 - 0.0041 17.1 0.9 0.021 14.7 0.3 2.3 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OAG20643.1 - 0.042 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 OAG20643.1 - 0.047 13.9 0.1 0.095 12.9 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FMN_dh PF01070.18 OAG20644.1 - 1.9e-116 388.9 0.0 2.2e-116 388.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG20644.1 - 1.5e-16 60.2 0.0 4.4e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 OAG20644.1 - 0.035 13.1 0.1 0.15 11.0 0.1 2.0 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAG20644.1 - 0.088 12.1 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 OAG20644.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Epimerase PF01370.21 OAG20645.1 - 2.6e-21 76.2 0.0 3.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG20645.1 - 1.5e-14 54.2 0.0 2.9e-14 53.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG20645.1 - 5.1e-14 51.9 0.0 7.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG20645.1 - 2.8e-08 33.2 0.1 8.4e-08 31.6 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAG20645.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG20645.1 - 1.7e-05 24.2 0.1 0.15 11.2 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 OAG20645.1 - 4.2e-05 23.7 0.1 7.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 OAG20645.1 - 0.0022 17.9 0.1 0.016 15.1 0.1 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG20645.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 OAG20646.1 - 1.5e-29 103.1 27.9 1.5e-29 103.1 27.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20646.1 - 2.7e-09 36.4 15.8 4.3e-09 35.8 15.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Dfp1_Him1_M PF08630.10 OAG20649.1 - 5.1e-37 126.9 0.2 3e-36 124.4 0.2 2.4 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAG20649.1 - 2.7e-20 72.2 0.2 2.7e-20 72.2 0.2 1.7 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.26 OAG20649.1 - 0.015 15.6 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CitT PF12431.8 OAG20649.1 - 0.074 13.4 1.7 0.38 11.2 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator Antimicrobial_7 PF08102.11 OAG20649.1 - 0.087 13.1 1.0 0.78 10.0 0.1 2.4 2 0 0 2 2 2 0 Scorpion antimicrobial peptide zf-C2H2_jaz PF12171.8 OAG20649.1 - 3.9 7.9 5.4 11 6.4 3.0 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding APG12 PF04110.13 OAG20650.1 - 9.8e-25 86.8 0.0 1.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ufm1 PF03671.14 OAG20650.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Atg8 PF02991.16 OAG20650.1 - 0.21 11.8 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Cupin_8 PF13621.6 OAG20651.1 - 4.5e-36 124.9 0.0 7.2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG20651.1 - 1.8e-06 27.7 0.0 8.8e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Reticulon PF02453.17 OAG20653.1 - 1.5e-34 119.2 2.3 2.1e-34 118.7 2.3 1.2 1 0 0 1 1 1 1 Reticulon NCOA_u2 PF16665.5 OAG20653.1 - 0.021 15.1 2.9 1.3 9.4 0.7 2.4 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein Apo-CIII PF05778.12 OAG20653.1 - 0.1 12.3 1.3 0.18 11.4 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) G_path_suppress PF15991.5 OAG20653.1 - 2.8 8.0 10.7 0.13 12.4 4.6 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor EMC3_TMCO1 PF01956.16 OAG20654.1 - 0.066 12.9 1.2 0.15 11.8 1.2 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HATPase_c PF02518.26 OAG20655.1 - 1.4e-24 86.7 0.0 3.7e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG20655.1 - 1.5e-20 73.5 0.3 5.7e-20 71.6 0.3 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG20655.1 - 7.9e-14 51.4 1.2 1.4e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG20655.1 - 0.00015 22.1 0.0 0.00071 19.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 OAG20655.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CN_hydrolase PF00795.22 OAG20656.1 - 1.6e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OAG20656.1 - 5.8e-25 87.8 0.0 3.7e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 NAD synthase CHASE5 PF17149.4 OAG20656.1 - 0.086 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins Cyanate_lyase PF02560.14 OAG20656.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain DUF2834 PF11196.8 OAG20660.1 - 0.00014 22.1 17.7 0.069 13.5 6.8 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF2834) Aa_trans PF01490.18 OAG20661.1 - 7.3e-81 272.0 24.5 9e-81 271.7 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhoLip_ATPase_C PF16212.5 OAG20661.1 - 0.0073 16.1 9.3 0.025 14.3 5.7 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal CAAD PF14159.6 OAG20661.1 - 4.1 7.3 5.6 1.6 8.6 0.6 3.0 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase zf-RING_2 PF13639.6 OAG20662.1 - 2.6e-08 34.1 2.9 3.9e-08 33.5 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG20662.1 - 3.6e-05 23.7 1.6 6.4e-05 22.9 1.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG20662.1 - 0.0001 22.5 2.9 0.00036 20.8 2.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG20662.1 - 0.00077 19.3 2.9 0.0012 18.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG20662.1 - 0.001 18.9 1.4 0.0017 18.2 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG20662.1 - 0.004 16.9 2.7 0.0092 15.8 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG20662.1 - 0.018 15.1 2.7 0.039 14.0 2.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAG20662.1 - 0.023 14.7 3.7 0.036 14.0 3.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 OAG20662.1 - 0.035 14.1 0.5 0.055 13.4 0.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_11 PF17123.5 OAG20662.1 - 0.27 11.0 2.1 0.44 10.3 2.1 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAG20662.1 - 0.36 11.0 1.3 0.71 10.1 1.3 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG20662.1 - 0.89 9.5 4.3 3.3 7.6 4.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DNA_topoisoIV PF00521.20 OAG20664.1 - 2.9e-124 415.2 0.2 2.9e-124 415.2 0.2 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAG20664.1 - 2e-50 170.4 1.5 6.9e-50 168.6 1.5 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAG20664.1 - 4.6e-27 94.6 4.6 1.1e-26 93.4 4.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAG20664.1 - 6.7e-14 52.4 0.2 1.6e-13 51.1 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAG20664.1 - 8e-07 29.2 0.0 4.3e-06 26.9 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 OAG20664.1 - 0.0022 17.8 4.3 0.0024 17.7 1.7 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ntox17 PF15524.6 OAG20664.1 - 0.18 12.1 4.4 0.76 10.1 0.3 3.4 3 0 0 3 3 3 0 Novel toxin 17 STPPase_N PF16891.5 OAG20664.1 - 0.42 11.1 2.0 0.93 10.0 0.2 2.6 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 OAG20665.1 - 4.1e-35 121.4 0.0 1.2e-34 119.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20665.1 - 6.6e-23 81.3 0.0 8.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG20665.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAG20665.1 - 0.093 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.23 OAG20666.1 - 8.3e-22 77.8 16.4 1e-21 77.5 16.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain PSP1 PF04468.12 OAG20667.1 - 1.5e-22 79.7 0.2 2.7e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region BRF1 PF07741.13 OAG20667.1 - 1.6 9.2 4.7 0.7 10.3 0.9 2.3 3 0 0 3 3 3 0 Brf1-like TBP-binding domain AIP3 PF03915.13 OAG20668.1 - 0.0093 15.1 1.8 0.011 14.9 1.8 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Ribosomal_L15e PF00827.17 OAG20669.1 - 3.6e-84 281.3 11.8 4.4e-84 281.0 11.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 DnaJ PF00226.31 OAG20670.1 - 8.1e-21 73.9 0.2 2.4e-20 72.4 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_43 PF04616.14 OAG20671.1 - 1.2e-28 100.2 3.1 4.8e-28 98.3 3.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 AAA_23 PF13476.6 OAG20673.1 - 1.6 9.2 10.0 1.7 9.1 5.1 2.2 2 0 0 2 2 2 0 AAA domain MOSC PF03473.17 OAG20674.1 - 1.9e-26 92.6 0.0 2.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG20674.1 - 2e-19 69.6 0.0 3.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DivIC PF04977.15 OAG20675.1 - 0.013 15.2 2.8 0.013 15.2 2.8 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF2805 PF10985.8 OAG20675.1 - 0.092 13.1 1.9 1 9.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2805) DUF1192 PF06698.11 OAG20675.1 - 0.14 12.2 1.9 0.41 10.7 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AlkA_N PF06029.11 OAG20675.1 - 0.15 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 AlkA N-terminal domain bZIP_2 PF07716.15 OAG20675.1 - 4.2 7.5 11.9 11 6.2 7.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Peroxidase_2 PF01328.17 OAG20676.1 - 1.4e-43 149.6 0.0 2e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Laminin_II PF06009.12 OAG20678.1 - 0.31 11.1 20.8 0.59 10.1 12.4 2.8 3 0 0 3 3 3 0 Laminin Domain II DUF4140 PF13600.6 OAG20678.1 - 0.83 10.1 14.0 3.1 8.3 0.5 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.6 OAG20678.1 - 2 7.7 29.4 2.4 7.5 18.6 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 OAG20678.1 - 3.8 8.0 9.8 1.8 9.1 0.9 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 OAG20678.1 - 3.9 7.9 15.6 0.15 12.5 5.0 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper APG6_N PF17675.1 OAG20678.1 - 4.7 7.8 30.3 4.4 7.8 17.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ING PF12998.7 OAG20680.1 - 4.1e-05 24.1 0.1 0.00014 22.4 0.1 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAG20680.1 - 0.00052 19.9 7.5 0.00087 19.1 7.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAG20680.1 - 0.025 14.8 1.4 0.054 13.8 1.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF2116 PF09889.9 OAG20680.1 - 0.037 14.0 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TFIIF_beta PF02270.15 OAG20680.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain zf-HC5HC2H_2 PF13832.6 OAG20680.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain 5_nucleotid_C PF02872.18 OAG20681.1 - 3.7e-40 137.7 0.0 6e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAG20681.1 - 7.2e-05 23.4 0.2 0.00014 22.5 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FGGY_C PF02782.16 OAG20683.1 - 3.6e-73 245.5 1.1 5.3e-73 245.0 1.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG20683.1 - 5.5e-66 222.6 0.0 7.4e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain adh_short PF00106.25 OAG20684.1 - 1.1e-06 28.3 0.0 0.049 13.1 0.0 3.2 2 1 1 3 3 3 3 short chain dehydrogenase KR PF08659.10 OAG20684.1 - 0.11 12.5 0.1 0.29 11.0 0.1 1.7 1 1 0 1 1 1 0 KR domain Phasin PF05597.11 OAG20684.1 - 0.17 11.9 1.2 1.3 9.1 0.8 2.5 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4164 PF13747.6 OAG20685.1 - 0.026 14.8 2.5 0.026 14.8 2.5 3.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 OAG20685.1 - 0.046 12.6 17.7 0.14 11.0 17.7 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 OAG20685.1 - 0.06 11.5 18.3 0.11 10.7 18.3 1.3 1 0 0 1 1 1 0 HOOK protein KASH_CCD PF14662.6 OAG20685.1 - 0.23 11.2 25.1 0.67 9.8 25.1 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fusion_gly PF00523.18 OAG20685.1 - 0.33 9.2 1.5 0.5 8.6 1.5 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Tweety PF04906.13 OAG20685.1 - 0.53 8.9 4.9 0.77 8.4 4.9 1.1 1 0 0 1 1 1 0 Tweety Macoilin PF09726.9 OAG20685.1 - 1.5 7.3 20.0 0.09 11.3 8.4 2.2 2 0 0 2 2 2 0 Macoilin family bZIP_1 PF00170.21 OAG20685.1 - 2.1 8.5 22.0 0.15 12.2 5.6 4.0 2 1 2 4 4 4 0 bZIP transcription factor DUF1751 PF08551.10 OAG20686.1 - 0.32 11.6 3.2 0.6 10.7 1.3 2.2 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF3429 PF11911.8 OAG20687.1 - 3.8e-43 147.2 14.3 5.6e-43 146.7 14.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2975 PF11188.8 OAG20687.1 - 0.21 11.5 1.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) VPS13_mid_rpt PF16910.5 OAG20688.1 - 1.5e-98 329.0 18.1 1.4e-95 319.2 1.1 5.3 5 1 1 6 6 6 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 OAG20688.1 - 7.3e-95 317.4 0.0 3.3e-94 315.3 0.0 2.1 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OAG20688.1 - 4.9e-84 281.8 3.4 3.9e-80 269.0 0.0 4.6 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAG20688.1 - 7.7e-73 244.0 4.5 3.5e-69 232.1 0.5 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAG20688.1 - 8.3e-41 138.8 0.0 2.8e-40 137.0 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAG20688.1 - 3.3e-05 24.1 0.1 0.00017 21.9 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF3128 PF11326.8 OAG20689.1 - 3.1e-26 91.5 3.9 4.6e-26 91.0 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HSP70 PF00012.20 OAG20690.1 - 5.7e-256 850.4 8.3 6.4e-256 850.3 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG20690.1 - 1.1e-16 60.6 0.0 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAG20690.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OAG20690.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 OAG20690.1 - 0.041 14.3 4.4 7.8 7.0 0.2 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Sds3 PF08598.11 OAG20692.1 - 6.1e-45 153.9 0.3 1e-44 153.1 0.3 1.6 1 1 0 1 1 1 1 Sds3-like DUF3245 PF11595.8 OAG20692.1 - 0.17 12.4 4.6 0.88 10.0 4.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) Thiolase_N PF00108.23 OAG20694.1 - 1e-90 303.7 1.7 1.4e-90 303.2 1.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG20694.1 - 4.3e-37 126.5 1.8 1.1e-36 125.2 0.5 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG20694.1 - 9.9e-05 22.0 4.5 0.00034 20.3 0.4 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG20694.1 - 0.0062 16.4 0.3 0.39 10.6 0.1 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF5419 PF17441.2 OAG20694.1 - 0.09 12.9 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5419) Homeobox_KN PF05920.11 OAG20695.1 - 1.1e-17 63.6 0.7 3.4e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OAG20695.1 - 1.9e-05 24.4 0.1 4.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 OAG20695.1 - 0.0024 18.6 1.8 0.0024 18.6 1.8 5.6 6 0 0 6 6 6 1 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.16 OAG20695.1 - 0.0025 17.8 0.0 0.0079 16.2 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_3rep PF18868.1 OAG20695.1 - 0.12 13.1 3.6 12 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OAG20695.1 - 0.24 11.7 9.0 4.8 7.6 4.1 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 OAG20695.1 - 0.37 10.7 4.2 15 5.6 0.1 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 OAG20695.1 - 0.71 10.5 29.2 0.68 10.5 1.7 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG20695.1 - 2 9.0 13.0 0.4 11.2 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG20697.1 - 1.2e-08 35.0 1.3 2.1e-08 34.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG20697.1 - 3.1e-06 27.4 0.9 5.9e-06 26.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type BRCT_assoc PF12820.7 OAG20697.1 - 0.029 14.2 0.3 0.029 14.2 0.3 2.3 2 1 0 2 2 2 0 Serine-rich domain associated with BRCT Fzo_mitofusin PF04799.13 OAG20697.1 - 0.068 12.7 3.6 0.11 12.1 3.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-C2H2_2 PF12756.7 OAG20697.1 - 0.068 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 OAG20697.1 - 0.11 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger GST_N_3 PF13417.6 OAG20698.1 - 6.5e-17 61.7 0.0 1.4e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG20698.1 - 3.1e-15 56.2 0.0 6.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG20698.1 - 2.4e-14 53.4 0.0 5.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OAG20698.1 - 1.8e-05 24.8 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin INCENP_ARK-bind PF03941.15 OAG20700.1 - 9.3e-17 60.7 1.2 9.3e-17 60.7 1.2 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Nucleo_P87 PF07267.11 OAG20701.1 - 0.28 10.0 2.3 0.35 9.7 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SET PF00856.28 OAG20703.1 - 7.7e-06 26.4 0.0 2.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 SET domain Thg1 PF04446.12 OAG20704.1 - 2.3e-37 127.8 0.0 3.1e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase EH_Signature PF15611.6 OAG20704.1 - 0.052 13.0 0.0 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain SurE PF01975.17 OAG20705.1 - 1.1e-29 103.6 0.5 1.4e-29 103.2 0.5 1.1 1 0 0 1 1 1 1 Survival protein SurE RCR PF12273.8 OAG20706.1 - 0.0003 21.4 1.2 0.0003 21.4 1.2 2.6 3 0 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red OAD_gamma PF04277.13 OAG20706.1 - 0.0012 19.4 7.3 0.048 14.3 0.0 2.6 3 0 0 3 3 3 2 Oxaloacetate decarboxylase, gamma chain DUF2070 PF09843.9 OAG20706.1 - 0.098 10.9 6.1 0.12 10.7 6.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Shisa PF13908.6 OAG20706.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.3 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator CcmD PF04995.14 OAG20706.1 - 0.43 10.7 0.0 0.43 10.7 0.0 2.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RIFIN PF02009.16 OAG20706.1 - 0.56 10.0 1.8 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Rifin Tad PF13400.6 OAG20706.1 - 0.58 10.5 0.1 0.58 10.5 0.1 3.7 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like LHC PF00556.20 OAG20706.1 - 8.6 6.7 9.0 1.3 9.3 0.6 2.5 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Peptidase_C1_2 PF03051.15 OAG20707.1 - 6.7e-157 522.8 0.0 7.8e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAG20707.1 - 1.1e-07 32.2 0.3 0.0035 17.5 0.1 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 OAG20707.1 - 0.018 15.6 0.1 0.04 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) TMEM237 PF15383.6 OAG20709.1 - 0.11 11.6 0.2 0.11 11.6 0.2 2.4 2 1 0 2 2 2 0 Transmembrane protein 237 Aminotran_1_2 PF00155.21 OAG20710.1 - 1.1e-60 205.7 0.0 1.4e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 OAG20710.1 - 0.0013 17.7 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Allinase DUF3472 PF11958.8 OAG20711.1 - 0.0031 18.0 1.9 0.78 10.2 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3472) PAM2 PF07145.15 OAG20711.1 - 0.19 11.5 8.1 6.4 6.7 0.1 4.1 4 0 0 4 4 4 0 Ataxin-2 C-terminal region An_peroxidase PF03098.15 OAG20712.1 - 4.1e-36 124.6 0.0 4.5e-26 91.5 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAG20712.1 - 8.1e-05 21.5 0.2 0.0024 16.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L6e PF01159.19 OAG20713.1 - 1.6e-36 125.2 1.7 1.6e-36 125.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e adh_short PF00106.25 OAG20714.1 - 6.8e-42 143.1 1.2 9.3e-42 142.7 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG20714.1 - 1.3e-31 110.0 0.1 1.8e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG20714.1 - 1.3e-10 41.4 3.9 4e-10 39.9 3.9 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG20714.1 - 0.12 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SlyX PF04102.12 OAG20716.1 - 0.042 14.5 0.5 0.59 10.8 0.1 2.3 1 1 1 2 2 2 0 SlyX TMPIT PF07851.13 OAG20716.1 - 0.13 11.5 0.5 0.16 11.2 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein CC2-LZ PF16516.5 OAG20716.1 - 0.14 12.5 2.7 0.19 12.1 1.3 2.0 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ALC PF17527.2 OAG20717.1 - 0.031 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Phage ALC protein DUF505 PF04458.12 OAG20717.1 - 0.15 10.4 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Cyclin_N PF00134.23 OAG20719.1 - 8.9e-15 54.6 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAG20719.1 - 7.2e-09 36.2 0.1 1.7e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin DUF4695 PF15766.5 OAG20719.1 - 0.059 13.6 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) C1ORF64 PF15547.6 OAG20719.1 - 1.3 9.4 6.7 0.59 10.6 0.2 2.3 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein Pkinase PF00069.25 OAG20722.1 - 3.2e-66 223.4 0.0 4.4e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20722.1 - 1.3e-32 113.1 0.0 3.7e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG20722.1 - 0.0029 17.0 0.0 0.015 14.6 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG20722.1 - 0.0049 15.9 0.1 0.0084 15.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG20722.1 - 0.0056 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAG20722.1 - 0.011 15.4 0.1 2.1 7.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG20722.1 - 0.019 14.9 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family GCFC PF07842.12 OAG20724.1 - 1.7e-64 218.1 1.2 2.7e-64 217.5 1.2 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAG20724.1 - 1.3e-10 41.0 8.3 3.2e-10 39.7 8.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG20724.1 - 0.00029 20.9 2.9 0.00029 20.9 2.9 2.0 2 0 0 2 2 2 1 G-patch domain Nup54 PF13874.6 OAG20724.1 - 0.05 13.7 1.1 0.1 12.7 1.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ABC_tran_CTD PF16326.5 OAG20724.1 - 0.57 10.5 8.8 0.19 12.0 4.8 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain MbeD_MobD PF04899.12 OAG20724.1 - 1.4 9.1 4.6 0.9 9.7 1.9 2.1 2 0 0 2 2 2 0 MbeD/MobD like DUF4140 PF13600.6 OAG20724.1 - 10 6.7 8.4 2.2 8.8 0.6 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lyase_1 PF00206.20 OAG20726.1 - 9.7e-20 71.2 0.1 2.1e-19 70.1 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 OAG20726.1 - 9.8e-16 58.1 0.0 3e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Acetyltransf_8 PF13523.6 OAG20727.1 - 3.1e-50 169.6 0.0 4.7e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG20727.1 - 0.021 15.5 0.1 0.045 14.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sod_Fe_C PF02777.18 OAG20728.1 - 5.1e-38 129.3 2.3 5.7e-38 129.2 0.5 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAG20728.1 - 8.7e-29 99.8 1.8 1.5e-28 99.0 1.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TMEM154 PF15102.6 OAG20729.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.5 2 0 0 2 2 2 0 TMEM154 protein family BatD PF13584.6 OAG20729.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Syndecan PF01034.20 OAG20729.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.11 OAG20729.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Treslin_N PF15292.6 OAG20729.1 - 0.37 9.1 1.3 0.47 8.7 1.3 1.1 1 0 0 1 1 1 0 Treslin N-terminus CHCH PF06747.13 OAG20730.1 - 0.085 13.0 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 CHCH domain zf-CCCH_4 PF18044.1 OAG20732.1 - 0.0002 21.1 3.9 0.0002 21.1 3.9 3.2 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG20732.1 - 0.00024 20.9 3.4 0.00024 20.9 3.4 3.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAG20732.1 - 0.00093 19.9 0.1 0.00093 19.9 0.1 2.1 3 0 0 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 OAG20732.1 - 0.0012 18.8 9.0 0.0012 18.8 9.0 3.5 3 0 0 3 3 3 1 Zinc finger domain Beta-lactamase PF00144.24 OAG20733.1 - 2.7e-47 161.6 0.0 4.3e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OAG20733.1 - 0.00014 22.2 0.0 0.00031 21.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Epimerase PF01370.21 OAG20735.1 - 4.1e-06 26.4 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG20735.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein AAA_12 PF13087.6 OAG20736.1 - 5.2e-31 107.8 0.0 1.7e-30 106.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG20736.1 - 1.1e-23 84.4 0.0 1.6e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG20736.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG20736.1 - 9.4e-09 35.3 0.0 8.5e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAG20736.1 - 5.8e-06 26.0 0.0 2.7e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 OAG20736.1 - 8.8e-05 22.4 0.0 0.00098 19.0 0.0 2.1 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 OAG20736.1 - 0.00021 21.1 0.0 0.34 10.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG20736.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG20736.1 - 0.00029 20.3 0.0 0.0013 18.3 0.0 2.0 3 0 0 3 3 3 1 PhoH-like protein UvrD_C PF13361.6 OAG20736.1 - 0.00079 18.9 0.1 0.074 12.4 0.0 2.9 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OAG20736.1 - 0.0097 16.2 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAG20736.1 - 0.026 14.4 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 OAG20736.1 - 0.033 14.0 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OAG20736.1 - 0.038 14.4 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OAG20736.1 - 0.044 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAG20736.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OAG20736.1 - 0.089 13.2 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG20736.1 - 0.12 11.5 0.0 0.84 8.8 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) zf-PHD-like PF15446.6 OAG20737.1 - 5.8e-69 231.0 12.1 1.3e-68 229.9 12.1 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 OAG20737.1 - 6.5e-54 183.0 0.1 1e-53 182.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 OAG20737.1 - 8.7e-28 96.0 0.6 2.2e-27 94.7 0.6 1.8 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 OAG20737.1 - 5.3e-20 71.8 0.0 1.2e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAG20737.1 - 3.3e-11 42.9 0.9 8e-11 41.6 0.9 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OAG20737.1 - 3e-07 30.6 0.0 6.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 OAG20737.1 - 7.7e-05 22.5 1.3 1.4 8.9 0.4 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OAG20737.1 - 0.00033 20.5 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 OAG20737.1 - 0.00059 19.7 3.7 0.00059 19.7 3.7 3.6 3 1 0 3 3 3 2 PHD-finger UBA PF00627.31 OAG20737.1 - 0.01 15.7 1.0 0.029 14.3 1.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Zf_RING PF16744.5 OAG20737.1 - 0.49 10.5 11.2 2.7 8.2 3.4 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger zinc_ribbon_4 PF13717.6 OAG20737.1 - 6.7 6.7 9.9 15 5.6 0.1 4.8 4 0 0 4 4 4 0 zinc-ribbon domain SpoU_methylase PF00588.19 OAG20738.1 - 1e-23 84.1 0.0 2.9e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OAG20738.1 - 1.7e-06 28.2 0.0 4.2e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding L_HMGIC_fpl PF10242.9 OAG20739.1 - 4e-05 23.9 4.7 4e-05 23.9 4.7 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 OAG20739.1 - 0.94 9.4 9.9 95 2.9 9.4 2.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like NACHT PF05729.12 OAG20740.1 - 1.7e-09 37.8 0.1 5.7e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG20740.1 - 5.1e-07 30.2 1.0 5.1e-06 27.0 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG20740.1 - 0.0002 21.6 0.1 0.0037 17.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG20740.1 - 0.002 18.6 0.1 0.041 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNR_N PF08343.10 OAG20740.1 - 0.013 15.5 0.4 0.036 14.1 0.4 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal APS_kinase PF01583.20 OAG20740.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 OAG20740.1 - 0.044 13.9 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG20740.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG20740.1 - 0.11 11.9 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 KaiC GAS PF13851.6 OAG20740.1 - 0.61 9.4 12.4 2.9 7.2 9.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 OAG20740.1 - 2.2 7.4 5.6 4 6.6 5.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein HeLo PF14479.6 OAG20741.1 - 2.1e-42 145.3 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET PF06985.11 OAG20742.1 - 9.8e-25 87.6 1.0 5.1e-24 85.3 0.0 2.5 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) HTH_Tnp_Tc5 PF03221.16 OAG20743.1 - 1.1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 OAG20743.1 - 0.0081 15.9 0.4 0.18 11.7 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HET PF06985.11 OAG20744.1 - 2.5e-27 96.0 0.0 1.7e-22 80.3 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GCIP PF13324.6 OAG20746.1 - 0.052 13.2 1.2 0.087 12.4 1.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF5407 PF17401.2 OAG20746.1 - 0.14 12.4 0.2 19 5.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5407) TRI12 PF06609.13 OAG20747.1 - 1.6e-191 637.8 24.9 2.2e-191 637.4 24.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG20747.1 - 4.6e-18 65.3 61.4 9.7e-17 60.9 56.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20747.1 - 1.9e-12 46.8 9.4 1.9e-12 46.8 9.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short_C2 PF13561.6 OAG20749.1 - 9.6e-54 182.4 2.2 1.2e-53 182.1 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20749.1 - 1.5e-43 148.5 1.2 2e-43 148.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20749.1 - 7e-05 22.8 0.6 0.00033 20.6 0.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG20749.1 - 0.029 13.8 0.1 0.4 10.1 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG20750.1 - 3.8e-43 147.2 0.0 5.1e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG20750.1 - 2.4e-41 141.8 0.4 2.9e-36 125.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG20750.1 - 3.4e-11 43.4 0.1 4.6e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L26 PF16906.5 OAG20750.1 - 0.025 15.1 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF1080 PF06439.11 OAG20753.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Mitofilin PF09731.9 OAG20757.1 - 0.26 10.1 18.4 0.37 9.6 18.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HET PF06985.11 OAG20759.1 - 6.6e-21 75.2 0.0 8.9e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2892 PF11127.8 OAG20760.1 - 0.053 13.6 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) MFS_1 PF07690.16 OAG20761.1 - 5e-21 75.0 20.6 5e-21 75.0 20.6 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 OAG20765.1 - 3.5e-50 171.1 47.9 4.3e-50 170.8 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG20765.1 - 1.4e-24 86.5 39.2 2e-24 86.1 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease SelR PF01641.18 OAG20766.1 - 2.2e-46 156.9 0.0 3.3e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.12 OAG20766.1 - 0.11 12.1 1.6 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 OAG20766.1 - 0.45 10.6 3.4 4 7.5 2.1 2.3 1 1 2 3 3 3 0 Double zinc ribbon NAD_binding_10 PF13460.6 OAG20767.1 - 4e-15 56.2 0.0 5.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG20767.1 - 1.2e-09 38.0 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG20767.1 - 2.5e-08 33.7 0.1 3.7e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG20767.1 - 5.1e-06 26.8 0.0 8.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG20767.1 - 0.00019 21.9 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG20767.1 - 0.00031 20.2 0.4 0.0025 17.3 0.1 2.1 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 OAG20767.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 OAG20767.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAG20767.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 OAG20767.1 - 0.041 14.5 0.0 0.082 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAG20767.1 - 0.074 13.9 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 OAG20767.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein K_oxygenase PF13434.6 OAG20767.1 - 0.18 10.9 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amidase PF01425.21 OAG20768.1 - 3.4e-70 237.3 0.1 7.6e-70 236.1 0.1 1.6 1 1 0 1 1 1 1 Amidase PNP_UDP_1 PF01048.20 OAG20769.1 - 5.1e-39 133.9 0.0 6.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.22 OAG20775.1 - 8.3e-33 113.8 0.8 6e-16 58.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4419 PF14388.6 OAG20775.1 - 0.075 12.4 1.1 0.35 10.3 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) KH_9 PF17904.1 OAG20775.1 - 0.22 11.9 0.8 9.8 6.6 0.1 2.4 2 0 0 2 2 2 0 FMRP KH0 domain Chorion_2 PF03964.15 OAG20776.1 - 0.086 13.7 0.0 0.13 13.1 0.0 1.2 1 0 0 1 1 1 0 Chorion family 2 ADC PF06314.11 OAG20777.1 - 1.7e-42 145.6 0.0 2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) polyprenyl_synt PF00348.17 OAG20780.1 - 1.2e-53 181.8 0.0 2.1e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 OAG20781.1 - 1.9e-38 132.4 0.0 2.4e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 OAG20783.1 - 2e-92 310.8 3.1 3.6e-92 309.9 3.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Aha1_N PF09229.11 OAG20784.1 - 1.8e-40 138.3 1.8 2.9e-40 137.6 1.8 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAG20784.1 - 8.4e-18 64.8 1.2 8.4e-18 64.8 1.2 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein SEA PF01390.20 OAG20784.1 - 0.11 12.6 1.2 0.92 9.6 0.5 2.2 2 0 0 2 2 2 0 SEA domain Inhibitor_I66 PF16850.5 OAG20785.1 - 1.2e-05 25.3 0.1 6.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I66 DUF4537 PF15057.6 OAG20785.1 - 0.042 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Trypsin PF00089.26 OAG20786.1 - 4.3e-63 213.1 3.1 5e-63 212.9 3.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OAG20786.1 - 1.3e-08 35.9 2.8 2e-08 35.3 2.8 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Aldo_ket_red PF00248.21 OAG20787.1 - 9.5e-20 71.0 0.0 4.8e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Flavokinase PF01687.17 OAG20788.1 - 1.4e-33 115.5 0.0 1.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 OAG20789.1 - 0.0051 16.9 8.7 0.01 16.0 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 OAG20789.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold MFS_1 PF07690.16 OAG20791.1 - 3e-37 128.3 33.2 3e-37 128.3 33.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG20791.1 - 1.2e-11 43.8 0.9 2.5e-11 42.7 0.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 OAG20792.1 - 1.4e-29 103.3 0.0 1.8e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20792.1 - 1.6e-21 76.7 0.0 2.1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20792.1 - 1.1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG20792.1 - 0.011 15.4 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ATP-grasp_5 PF13549.6 OAG20792.1 - 0.046 13.2 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Proteasome PF00227.26 OAG20794.1 - 1.8e-60 203.7 0.1 2.2e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG20794.1 - 3.8e-13 48.8 0.1 8.8e-13 47.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 OAG20794.1 - 0.015 15.4 0.2 0.037 14.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 OAG20794.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.19 OAG20795.1 - 4e-13 49.3 8.5 9.5e-12 44.9 0.1 3.5 4 0 0 4 4 4 2 FF domain WW PF00397.26 OAG20795.1 - 1.5e-09 37.7 6.6 2.2e-08 34.0 2.1 2.6 2 0 0 2 2 2 2 WW domain SPOC PF07744.13 OAG20797.1 - 5e-19 68.7 0.0 9.1e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 OAG20797.1 - 5.5e-18 65.5 0.5 1e-17 64.6 0.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAG20797.1 - 1.3e-08 34.6 12.1 2.3e-08 33.8 12.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG20797.1 - 1 9.0 6.7 1.8 8.2 6.7 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.6 OAG20797.1 - 4.9 7.6 10.8 1.1 9.7 5.6 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx CENP-Q PF13094.6 OAG20798.1 - 0.0018 18.5 1.9 0.0018 18.5 1.9 2.3 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit ArfGap PF01412.18 OAG20799.1 - 3e-40 136.9 0.7 4.6e-40 136.3 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GBS_Bsp-like PF08481.10 OAG20799.1 - 0.085 13.0 0.3 0.085 13.0 0.3 1.7 2 0 0 2 2 2 0 GBS Bsp-like repeat partial_CstF PF15861.5 OAG20799.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Synaptobrevin PF00957.21 OAG20800.1 - 0.055 13.3 2.5 0.55 10.1 0.4 2.0 1 1 1 2 2 2 0 Synaptobrevin DUF2993 PF11209.8 OAG20801.1 - 0.004 17.4 0.2 0.11 12.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2993) Mid2 PF04478.12 OAG20801.1 - 0.07 13.0 0.1 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2407_C PF13373.6 OAG20801.1 - 0.083 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain NCU-G1 PF15065.6 OAG20801.1 - 0.19 10.7 0.8 0.33 9.9 0.8 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Glyco_hydro2_C5 PF18565.1 OAG20802.1 - 3.3e-32 110.4 1.3 4.9e-32 109.8 0.2 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 OAG20802.1 - 1.8e-29 102.8 0.1 1.1e-28 100.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 OAG20802.1 - 3.6e-22 78.1 0.1 9.6e-22 76.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 OAG20802.1 - 1.6e-19 70.5 0.0 3.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OAG20802.1 - 1.3e-16 61.2 0.2 3.5e-16 59.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG20802.1 - 7.4e-05 23.3 0.1 0.00036 21.1 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 OAG20802.1 - 0.00096 19.4 5.4 0.012 16.0 0.2 3.3 3 0 0 3 3 3 1 Invasin, domain 3 SoxY PF13501.6 OAG20802.1 - 0.061 13.5 0.2 0.43 10.8 0.3 2.2 2 0 0 2 2 2 0 Sulfur oxidation protein SoxY Big_1 PF02369.16 OAG20802.1 - 2.9 7.9 8.4 0.17 11.9 0.6 2.9 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 1) Metallopep PF12044.8 OAG20803.1 - 4.5e-129 430.8 0.0 5.5e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 OAG20803.1 - 0.025 15.1 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OAG20803.1 - 0.1 11.5 0.2 0.18 10.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Ribosomal_L2_C PF03947.18 OAG20803.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Lipoprotein_15 PF03640.15 OAG20803.1 - 0.27 10.8 1.0 0.66 9.6 1.0 1.7 1 0 0 1 1 1 0 Secreted repeat of unknown function TehB PF03848.14 OAG20804.1 - 0.042 13.3 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB 5_nucleotid_C PF02872.18 OAG20806.1 - 8.7e-35 120.3 0.2 1.8e-34 119.3 0.2 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAG20806.1 - 4.8e-10 40.3 0.1 8.2e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rep_fac-A_C PF08646.10 OAG20806.1 - 0.075 12.8 0.3 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain Peptidase_C2 PF00648.21 OAG20808.1 - 6.7e-65 219.0 0.6 4.3e-42 144.2 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease AvrLm4-7 PF18661.1 OAG20808.1 - 0.13 13.3 0.2 0.4 11.7 0.2 1.8 1 0 0 1 1 1 0 Avirulence Effector AvrLm4-7 FAD_binding_4 PF01565.23 OAG20809.1 - 1.1e-21 77.1 0.2 2.4e-21 76.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG20809.1 - 0.00016 21.7 0.2 0.00038 20.5 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like CF222 PF15661.5 OAG20811.1 - 5.4 5.8 5.8 7.3 5.3 5.8 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family Nuc_sug_transp PF04142.15 OAG20812.1 - 2.6e-106 355.3 12.9 4.6e-106 354.5 12.9 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.16 OAG20812.1 - 1.3e-27 96.6 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAG20812.1 - 3.6e-22 79.0 0.0 7.3e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG20812.1 - 5.6e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG20812.1 - 1.2e-07 32.0 0.0 4.6e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EamA PF00892.20 OAG20812.1 - 2.8e-05 24.3 5.8 2.8e-05 24.3 5.8 2.4 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 OAG20812.1 - 0.00013 21.3 9.0 0.00013 21.3 9.0 1.7 1 1 0 1 1 1 1 UAA transporter family AAA_22 PF13401.6 OAG20812.1 - 0.0071 16.6 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain EmrE PF13536.6 OAG20812.1 - 0.0082 15.8 0.9 0.0082 15.8 0.9 1.9 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 OAG20812.1 - 0.04 13.3 11.2 0.0085 15.5 2.0 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family PUNUT PF16913.5 OAG20812.1 - 0.071 12.3 15.6 0.11 11.7 4.0 2.5 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport HET PF06985.11 OAG20813.1 - 1.8e-33 115.9 0.1 2.7e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CbtB PF09489.10 OAG20813.1 - 0.1 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) WD40 PF00400.32 OAG20814.1 - 9.7e-30 102.2 13.7 3e-05 24.7 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 OAG20814.1 - 7.5e-11 41.8 1.7 1.6e-10 40.7 1.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG20814.1 - 4.9e-07 29.5 0.8 8.9e-07 28.6 0.8 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OAG20814.1 - 3.4e-06 27.3 0.0 0.64 10.4 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG20814.1 - 0.00012 20.9 0.0 2.1 6.9 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OAG20814.1 - 0.011 15.7 0.0 32 4.6 0.0 3.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OAG20814.1 - 0.042 13.2 0.1 5.2 6.3 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain PH_10 PF15411.6 OAG20815.1 - 3.2e-38 130.8 0.6 7.6e-38 129.5 0.6 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OAG20815.1 - 1.3e-32 111.9 0.3 5e-32 110.0 0.0 2.0 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 OAG20815.1 - 2.9e-29 102.6 0.1 5.5e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 OAG20815.1 - 1.3e-10 41.1 0.0 3.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 OAG20815.1 - 0.047 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 PH domain Acetyltransf_1 PF00583.25 OAG20816.1 - 2.2e-11 44.0 0.1 4.9e-11 42.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG20816.1 - 1.2e-10 41.2 0.0 7.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 OAG20816.1 - 2.9e-10 40.2 0.0 2.7e-09 37.0 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG20816.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG20816.1 - 7e-06 26.1 0.0 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG20816.1 - 7.3e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 OAG20816.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 OAG20818.1 - 4.1e-25 88.4 61.5 1.8e-14 53.5 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG20818.1 - 3.7 6.3 21.4 0.35 9.7 12.2 2.7 2 1 0 2 2 2 0 MFS_1 like family Response_reg PF00072.24 OAG20820.1 - 9.1e-17 61.3 0.1 6.9e-16 58.4 0.0 2.5 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG20820.1 - 1.4e-09 37.8 0.6 5.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 OAG20820.1 - 2.9e-05 24.6 0.0 5.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_4 PF01565.23 OAG20821.1 - 4e-22 78.4 0.9 8.2e-22 77.4 0.9 1.5 1 1 0 1 1 1 1 FAD binding domain Peptidase_M14 PF00246.24 OAG20822.1 - 5.3e-38 131.5 0.6 7.8e-38 130.9 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase LysR_substrate PF03466.20 OAG20822.1 - 0.047 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain AstE_AspA PF04952.14 OAG20822.1 - 0.18 10.8 0.0 3.2 6.8 0.0 2.7 3 1 0 3 3 3 0 Succinylglutamate desuccinylase / Aspartoacylase family AMP-binding PF00501.28 OAG20823.1 - 9.7e-54 182.6 0.0 1.5e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG20823.1 - 0.0012 19.8 0.0 0.0041 18.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ferric_reduct PF01794.19 OAG20823.1 - 0.28 11.3 5.6 0.75 9.9 5.6 1.8 1 0 0 1 1 1 0 Ferric reductase like transmembrane component SdpI PF13630.6 OAG20823.1 - 0.71 10.0 9.8 0.15 12.2 1.1 3.0 2 0 0 2 2 2 0 SdpI/YhfL protein family Ribosomal_60s PF00428.19 OAG20825.1 - 2.9e-08 34.2 0.2 3.7e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2999 PF11212.8 OAG20825.1 - 0.014 15.6 0.0 2.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Ntox27 PF15531.6 OAG20825.1 - 0.064 13.2 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin 27 CN_hydrolase PF00795.22 OAG20826.1 - 1e-30 107.0 0.0 3.3e-30 105.3 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase YhcG_C PF06250.11 OAG20826.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain FMN_dh PF01070.18 OAG20827.1 - 1.6e-89 300.4 0.0 1.1e-47 162.8 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG20827.1 - 0.00027 20.1 0.1 0.0011 18.0 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG20827.1 - 0.0003 20.3 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 OAG20827.1 - 0.00059 19.1 0.3 0.49 9.5 0.0 2.4 2 1 1 3 3 3 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 OAG20827.1 - 0.0017 17.8 0.2 1.2 8.6 0.0 3.0 1 1 2 3 3 3 2 Histidine biosynthesis protein Glu_synthase PF01645.17 OAG20827.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 OAG20827.1 - 0.2 11.1 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator BOFC_N PF08977.10 OAG20827.1 - 0.22 11.6 0.9 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal Asparaginase_II PF06089.12 OAG20828.1 - 2.8e-107 358.5 0.8 3.3e-107 358.3 0.8 1.0 1 0 0 1 1 1 1 L-asparaginase II Complex1_51K PF01512.17 OAG20832.1 - 2e-47 160.8 0.0 3.5e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAG20832.1 - 2.9e-29 101.0 1.5 3.6e-29 100.7 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAG20832.1 - 3.2e-08 33.3 0.1 9.2e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 SLBB domain GHMP_kinases_C PF08544.13 OAG20832.1 - 0.11 12.8 0.0 24 5.4 0.0 2.5 2 0 0 2 2 2 0 GHMP kinases C terminal DUF3568 PF12092.8 OAG20832.1 - 0.14 12.2 0.4 0.27 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) EF-hand_1 PF00036.32 OAG20833.1 - 4.8e-21 72.7 7.6 3.4e-09 35.6 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OAG20833.1 - 8.4e-20 71.0 3.0 1.8e-11 44.3 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG20833.1 - 7e-18 63.0 5.2 6.5e-08 31.9 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OAG20833.1 - 1.3e-16 60.1 4.5 3.8e-10 39.4 0.3 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG20833.1 - 4.6e-14 51.2 2.9 2.4e-05 23.6 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OAG20833.1 - 2.2e-06 27.6 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAG20833.1 - 0.0026 18.0 0.1 1.9 8.9 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain DUF4834 PF16118.5 OAG20833.1 - 0.0027 18.6 1.2 0.11 13.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Caleosin PF05042.13 OAG20833.1 - 0.0063 16.5 0.0 0.54 10.2 0.0 2.6 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 OAG20833.1 - 0.012 16.0 2.4 1 9.7 0.1 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3323 PF11796.8 OAG20833.1 - 0.044 13.7 0.9 0.13 12.1 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DDOST_48kD PF03345.14 OAG20833.1 - 0.057 12.3 0.1 0.075 11.9 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta EF-hand_11 PF08976.11 OAG20833.1 - 0.064 14.1 0.1 0.18 12.7 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain DUF1296 PF06972.11 OAG20833.1 - 0.085 13.0 0.4 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) MgtE_N PF03448.17 OAG20833.1 - 0.25 12.0 2.6 1.2 9.8 0.3 2.4 2 0 0 2 2 2 0 MgtE intracellular N domain Nup96 PF12110.8 OAG20834.1 - 5.6e-85 285.0 0.5 8.1e-85 284.5 0.5 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAG20834.1 - 4.1e-44 150.3 0.0 7.3e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAG20834.1 - 2.9e-15 56.9 365.1 9.7e-09 36.0 43.0 12.9 4 2 9 13 13 13 9 Nucleoporin FG repeat region RCC1 PF00415.18 OAG20835.1 - 8e-23 80.8 0.2 4.4e-07 30.4 0.0 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG20835.1 - 1.2e-12 47.3 6.5 1.1e-08 34.6 0.1 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAG20835.1 - 1e-09 38.6 0.0 4.8e-05 23.6 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 OAG20835.1 - 2.2e-09 37.6 0.3 1.2e-08 35.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG20835.1 - 6.1e-08 33.2 0.1 1.4e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG20835.1 - 1.5e-05 25.0 0.3 0.16 12.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG20835.1 - 0.0025 18.1 0.1 1.4 9.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG20835.1 - 0.0078 16.6 0.3 2.2 8.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat ATG13 PF10033.9 OAG20836.1 - 8.5e-68 228.6 0.0 1.5e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Ubie_methyltran PF01209.18 OAG20837.1 - 7.1e-82 274.2 0.0 8.7e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAG20837.1 - 3.3e-15 56.6 0.0 6.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG20837.1 - 4.1e-13 49.8 0.0 8.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG20837.1 - 1.9e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG20837.1 - 2.6e-09 37.7 0.0 4.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG20837.1 - 2.3e-07 30.8 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain E1_dh PF00676.20 OAG20838.1 - 4.8e-89 298.3 0.0 5.9e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OAG20838.1 - 0.0011 18.7 1.9 0.0055 16.5 0.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OAG20838.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-C4H2 PF10146.9 OAG20838.1 - 0.23 11.8 1.7 0.48 10.7 1.7 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Rad4 PF03835.15 OAG20839.1 - 9.5e-36 122.7 1.7 3.5e-35 120.8 1.7 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG20839.1 - 3.3e-27 94.7 0.0 5.7e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG20839.1 - 7.3e-19 67.4 0.1 1.4e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG20839.1 - 4.2e-18 66.0 0.1 4.2e-18 66.0 0.1 3.3 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAG20839.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily E1-E2_ATPase PF00122.20 OAG20841.1 - 3.2e-38 131.0 0.0 6.8e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG20841.1 - 1.1e-23 84.7 0.0 1.9e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG20841.1 - 3e-05 23.9 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG20841.1 - 0.00012 22.4 0.1 0.00021 21.7 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF4295 PF14128.6 OAG20841.1 - 0.044 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) HET PF06985.11 OAG20842.1 - 1.5e-30 106.5 0.0 2.6e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) dsrm PF00035.26 OAG20843.1 - 0.019 15.7 0.0 0.052 14.3 0.0 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.7 OAG20843.1 - 0.038 14.2 0.8 0.15 12.4 0.8 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Dabb PF07876.12 OAG20844.1 - 9.4e-05 23.0 0.2 0.00045 20.8 0.1 1.9 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain NTP_transferase PF00483.23 OAG20846.1 - 8.7e-53 179.4 0.0 1.8e-52 178.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 OAG20846.1 - 6.8e-15 54.1 6.4 1.3e-10 40.6 0.8 3.4 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) 2_5_RNA_ligase2 PF13563.6 OAG20846.1 - 1.3e-14 54.4 0.0 2.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily NTP_transf_3 PF12804.7 OAG20846.1 - 2.7e-12 47.4 0.0 6.8e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAG20846.1 - 6e-08 32.3 4.6 2.2e-06 27.3 0.5 2.8 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 OAG20846.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase DUF4954 PF16314.5 OAG20846.1 - 0.012 13.8 0.1 0.034 12.3 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) IspD PF01128.19 OAG20846.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Flg_new PF09479.10 OAG20846.1 - 0.081 13.1 0.3 0.28 11.4 0.3 2.0 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) ubiquitin PF00240.23 OAG20848.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 OAG20848.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG20848.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG20848.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG20848.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG20848.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG20848.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAG20848.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAG20848.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 OAG20848.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 OAG20848.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAG20848.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 OAG20848.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 OAG20848.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 OAG20848.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 OAG20848.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 OAG20848.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 OAG20848.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAG20848.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 OAG20848.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 OAG20848.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 OAG20848.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 OAG20848.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 OAG20848.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 OAG20848.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 OAG20848.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 OAG20848.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Aldo_ket_red PF00248.21 OAG20849.1 - 3.3e-69 233.3 0.2 3.8e-69 233.1 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 OAG20851.1 - 0.0051 16.9 7.8 0.012 15.7 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 OAG20852.1 - 1.8e-06 27.5 0.0 3.7e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Prenyltrans PF00432.21 OAG20853.1 - 2.1e-33 113.7 30.5 7.8e-09 35.1 3.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pro_CA PF00484.19 OAG20854.1 - 5.7e-47 159.9 0.4 6.8e-47 159.7 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ARID PF01388.21 OAG20855.1 - 3.1e-19 69.4 0.0 8.2e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 OAG20855.1 - 0.0036 17.9 0.0 0.02 15.5 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Meiotic_rec114 PF03525.14 OAG20856.1 - 0.00014 21.0 1.0 0.0033 16.5 0.0 2.4 2 1 0 2 2 2 2 Meiotic recombination protein rec114 Diphthamide_syn PF01866.17 OAG20857.1 - 8.1e-86 288.2 0.0 1.3e-85 287.5 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein PLA2_B PF01735.18 OAG20858.1 - 3.4e-179 596.3 3.7 4.1e-179 596.1 3.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain COesterase PF00135.28 OAG20860.1 - 3.1e-71 240.8 0.1 8.7e-71 239.3 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG20860.1 - 8e-10 38.9 0.1 2.4e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAG20861.1 - 3.1e-20 72.9 0.1 7.4e-20 71.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG20861.1 - 3.3e-18 65.8 0.0 5.9e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG20861.1 - 1.7e-14 55.0 0.0 2.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAG20861.1 - 2.8e-05 22.9 0.0 4.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 OAG20861.1 - 0.00085 19.5 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 OAG20861.1 - 0.0033 17.3 0.0 0.0062 16.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG20861.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 OAG20861.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 OAG20861.1 - 0.023 14.5 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 OAG20861.1 - 0.024 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 OAG20861.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2358 PF10184.9 OAG20861.1 - 0.065 13.5 0.4 0.25 11.6 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Chlorophyllase2 PF12740.7 OAG20861.1 - 0.066 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 OAG20861.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 OAG20861.1 - 0.17 10.8 0.0 0.57 9.2 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase DIOX_N PF14226.6 OAG20863.1 - 2.3e-30 105.7 0.0 3.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG20863.1 - 1.6e-20 73.5 0.0 2.8e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sel1 PF08238.12 OAG20863.1 - 0.042 14.5 0.0 4.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Sel1 repeat NTP_transferase PF00483.23 OAG20864.1 - 3.2e-31 108.8 0.0 4.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OAG20864.1 - 2.9e-12 45.8 4.8 5.7e-08 32.2 0.1 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG20864.1 - 4.9e-08 33.5 0.0 9.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OAG20864.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hen1_L PF12623.7 OAG20866.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Complex1_30kDa PF00329.19 OAG20867.1 - 1.6e-44 151.5 0.0 2.1e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1349 PF07081.11 OAG20868.1 - 5.7e-20 71.8 0.0 7.3e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Not1 PF04054.15 OAG20870.1 - 0.12 11.2 1.2 0.14 11.1 1.2 1.0 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 TRAM_LAG1_CLN8 PF03798.16 OAG20871.1 - 5.8e-50 169.8 13.1 5.8e-50 169.8 13.1 1.6 2 0 0 2 2 2 1 TLC domain Med29 PF11568.8 OAG20872.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 29 tRNA-synt_2b PF00587.25 OAG20873.1 - 1.3e-21 77.4 0.0 9.3e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG20873.1 - 3.8e-13 49.6 2.6 6.8e-13 48.8 2.6 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OAG20873.1 - 0.011 15.5 1.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 OAG20873.1 - 0.019 15.2 1.6 0.037 14.3 1.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Dynactin_p22 PF07426.11 OAG20873.1 - 0.078 12.8 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Dynactin subunit p22 FapA PF03961.13 OAG20873.1 - 0.18 10.3 0.5 0.28 9.8 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 OAG20873.1 - 1.6 9.1 5.5 10 6.5 5.7 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) BTB PF00651.31 OAG20874.1 - 0.12 12.6 0.0 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Hydrophobin_2 PF06766.11 OAG20875.1 - 4.7e-20 71.3 11.6 6.4e-20 70.9 11.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin UQ_con PF00179.26 OAG20876.1 - 7e-44 148.9 0.0 7.8e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG20876.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B DEAD PF00270.29 OAG20877.1 - 6.7e-37 126.9 0.0 3.8e-36 124.5 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG20877.1 - 1.8e-20 73.3 0.0 5.4e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG20877.1 - 2.2e-19 69.4 0.0 4.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAG20877.1 - 0.014 15.4 0.0 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG20877.1 - 0.048 13.9 1.3 0.86 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain SnAPC_2_like PF11035.8 OAG20877.1 - 0.2 11.8 7.4 0.33 11.1 7.4 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb SLAC1 PF03595.17 OAG20880.1 - 1.1e-81 274.7 53.1 1.2e-81 274.5 53.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel UbiA PF01040.18 OAG20882.1 - 2.4 7.4 8.9 0.089 12.1 2.4 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family Aldose_epim PF01263.20 OAG20884.1 - 2.6e-49 168.2 0.1 3.2e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Amidohydro_1 PF01979.20 OAG20886.1 - 5.3e-05 22.7 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG20886.1 - 0.00049 19.7 0.0 0.067 12.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family SWIB PF02201.18 OAG20887.1 - 9.8e-21 73.4 0.0 2.3e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C2H2 PF00096.26 OAG20888.1 - 1.1e-07 31.8 12.7 0.049 14.1 3.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG20888.1 - 0.00015 22.3 12.2 0.22 12.5 0.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger C1_4 PF07975.12 OAG20888.1 - 0.0025 18.0 0.2 0.0093 16.2 0.2 2.0 1 1 0 1 1 1 1 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 OAG20888.1 - 0.0039 17.9 1.8 1.1 9.9 0.5 2.9 1 1 2 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 OAG20888.1 - 0.02 15.3 0.2 12 6.4 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Adeno_E3_CR2 PF02439.15 OAG20888.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-H2C2_2 PF13465.6 OAG20888.1 - 0.25 11.8 5.7 9.2 6.9 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 OAG20889.1 - 2e-05 24.8 6.2 0.075 13.5 0.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG20889.1 - 0.0029 18.3 8.3 0.22 12.4 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger C1_4 PF07975.12 OAG20889.1 - 0.029 14.6 0.8 0.072 13.3 0.8 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 OAG20889.1 - 0.83 10.3 3.7 1.2 9.8 0.5 2.5 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 OAG20889.1 - 1 9.5 5.5 4.2 7.6 5.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.25 OAG20890.1 - 8.2e-63 212.2 0.0 1.1e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG20890.1 - 9.9e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG20890.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG20890.1 - 0.00015 21.2 0.3 0.00033 20.1 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG20890.1 - 0.00075 18.4 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG20890.1 - 0.0092 15.9 2.3 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG20890.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Endonuc_Holl PF10107.9 OAG20890.1 - 0.18 11.6 0.2 0.46 10.3 0.0 1.6 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF747 PF05346.11 OAG20891.1 - 1e-120 403.1 5.5 1.4e-120 402.6 5.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family 4HBT_3 PF13622.6 OAG20892.1 - 5.7e-45 154.5 0.0 7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG20892.1 - 5.5e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase 4HBT PF03061.22 OAG20892.1 - 0.0018 18.6 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily ABC2_membrane PF01061.24 OAG20893.1 - 8.7e-88 293.2 62.9 4.9e-46 156.8 27.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 OAG20893.1 - 9.4e-37 124.8 12.1 5.2e-32 109.6 0.0 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.27 OAG20893.1 - 1.3e-36 126.1 0.1 6.2e-17 62.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.6 OAG20893.1 - 2.2e-19 69.8 1.0 3.6e-19 69.1 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 OAG20893.1 - 2.7e-06 27.1 0.1 9.2e-05 22.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAG20893.1 - 1.7e-05 25.3 3.1 0.0013 19.2 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG20893.1 - 4.9e-05 23.3 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OAG20893.1 - 5.5e-05 23.1 0.0 0.63 9.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG20893.1 - 0.00016 21.2 0.0 0.13 11.6 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG20893.1 - 0.00019 21.1 0.9 0.02 14.6 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 OAG20893.1 - 0.00025 21.3 0.1 0.11 12.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 OAG20893.1 - 0.00036 19.8 44.8 0.0018 17.5 20.8 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 OAG20893.1 - 0.00074 20.1 0.0 0.05 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG20893.1 - 0.0073 16.6 0.3 1.2 9.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAG20893.1 - 0.016 15.7 0.1 0.095 13.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 OAG20893.1 - 0.076 12.6 1.3 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAG20893.1 - 0.2 11.6 1.8 5.5 6.9 0.5 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAG20893.1 - 0.29 10.8 0.9 14 5.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG20893.1 - 0.31 10.7 2.0 8.4 6.1 0.5 2.4 2 0 0 2 2 2 0 AAA domain MFS_MOT1 PF16983.5 OAG20894.1 - 9.4e-56 187.0 36.3 2.6e-31 108.3 9.6 2.8 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily adh_short_C2 PF13561.6 OAG20895.1 - 4e-50 170.5 0.2 5.6e-50 170.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG20895.1 - 3.2e-43 147.5 0.2 3.9e-43 147.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG20895.1 - 3.5e-14 53.1 0.3 5.6e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG20895.1 - 0.14 11.6 0.1 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 OAG20897.1 - 8.4e-05 23.1 0.0 3.4 8.3 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG20897.1 - 0.00068 20.2 1.5 61 4.4 0.0 4.8 3 2 2 5 5 5 0 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG20897.1 - 0.0053 16.1 3.3 0.025 14.0 0.7 2.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAG20897.1 - 0.015 15.5 0.2 0.065 13.4 0.0 2.1 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank PF00023.30 OAG20897.1 - 0.12 12.8 0.1 2.9 8.5 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeat Zn_clus PF00172.18 OAG20898.1 - 2.2e-09 37.3 12.5 3.3e-09 36.7 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N_NLPC_P60 PF12912.7 OAG20900.1 - 0.24 11.8 3.4 0.17 12.3 0.8 2.2 1 1 1 2 2 2 0 NLPC_P60 stabilising domain, N term WD40 PF00400.32 OAG20903.1 - 5.9e-56 185.2 19.4 8.5e-10 39.1 0.5 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG20903.1 - 6.7e-15 55.2 0.0 4.6e-05 23.6 0.0 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG20903.1 - 1.5e-07 30.5 0.0 0.00029 19.6 0.0 3.6 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG20903.1 - 1.6e-05 23.9 0.2 0.36 9.5 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like bZIP_1 PF00170.21 OAG20903.1 - 0.028 14.5 0.4 0.055 13.6 0.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor CLASP_N PF12348.8 OAG20904.1 - 2.8e-05 23.8 1.4 0.0017 17.9 0.7 2.7 2 1 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 OAG20904.1 - 0.00074 19.9 2.1 0.29 11.5 0.0 4.3 3 1 2 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 OAG20904.1 - 0.00083 18.0 1.0 0.0035 16.0 1.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region TAN PF11640.8 OAG20904.1 - 0.0032 17.6 0.7 0.012 15.7 0.7 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair HAP1_N PF04849.13 OAG20904.1 - 0.0036 16.6 5.4 0.0094 15.2 5.4 1.6 1 0 0 1 1 1 1 HAP1 N-terminal conserved region MMS19_N PF14500.6 OAG20904.1 - 0.0053 16.4 1.3 0.16 11.6 0.2 3.3 2 2 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 OAG20904.1 - 0.0094 16.0 0.0 1.9 8.5 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG20904.1 - 0.011 15.9 1.2 89 3.8 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat HALZ PF02183.18 OAG20904.1 - 0.094 13.0 2.5 0.13 12.5 0.7 2.3 2 0 0 2 2 1 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 OAG20904.1 - 0.11 12.0 8.2 0.23 10.9 8.2 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 OAG20904.1 - 0.17 11.0 6.8 0.46 9.5 6.8 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 USP8_interact PF08941.10 OAG20904.1 - 0.47 10.2 3.4 0.88 9.4 0.3 2.8 2 1 1 3 3 3 0 USP8 interacting DivIC PF04977.15 OAG20904.1 - 1.1 9.1 12.5 1.1 9.0 4.9 3.1 1 1 1 2 2 2 0 Septum formation initiator MctB PF11382.8 OAG20904.1 - 1.2 8.8 5.0 2.5 7.8 3.9 2.2 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB Spc7 PF08317.11 OAG20904.1 - 1.7 7.5 13.6 0.095 11.6 7.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 OAG20904.1 - 2.3 8.4 5.9 6.3 7.0 5.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2956 PF11169.8 OAG20904.1 - 3.3 8.0 8.1 4.1 7.6 0.0 3.5 3 1 2 5 5 3 0 Protein of unknown function (DUF2956) Exonuc_VII_L PF02601.15 OAG20904.1 - 7.1 6.1 12.0 0.91 9.0 1.9 2.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit G-gamma PF00631.22 OAG20904.1 - 7.2 6.7 9.3 2.9 7.9 0.3 3.4 4 0 0 4 4 2 0 GGL domain WXG100 PF06013.12 OAG20904.1 - 7.5 6.9 7.9 8.5 6.7 0.3 3.6 3 0 0 3 3 2 0 Proteins of 100 residues with WXG HalX PF08663.10 OAG20904.1 - 7.7 6.9 11.5 8 6.9 2.2 2.9 2 0 0 2 2 2 0 HalX domain NYD-SP28_assoc PF14775.6 OAG20904.1 - 9.3 6.4 6.8 27 5.0 0.8 3.1 1 1 1 2 2 2 0 Sperm tail C-terminal domain Aminotran_1_2 PF00155.21 OAG20905.1 - 1.4e-32 113.3 0.0 1.7e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG20905.1 - 0.078 11.9 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V DHBP_synthase PF00926.19 OAG20906.1 - 2.9e-79 265.1 0.0 3.4e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Xan_ur_permease PF00860.20 OAG20907.1 - 1.6e-21 76.5 31.6 6.2e-21 74.5 29.1 2.6 2 1 0 2 2 2 1 Permease family DUF4956 PF16316.5 OAG20907.1 - 4.3 7.0 10.5 0.35 10.5 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4956) Aldo_ket_red PF00248.21 OAG20909.1 - 3.6e-65 220.1 0.0 4.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MCU PF04678.13 OAG20910.1 - 1.3e-26 93.8 1.0 1.3e-26 93.8 1.0 2.2 2 0 0 2 2 2 1 Mitochondrial calcium uniporter DUF1281 PF06924.11 OAG20910.1 - 0.29 10.6 1.2 0.55 9.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) CrgA PF06781.12 OAG20910.1 - 2.8 8.1 5.0 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA RRM_1 PF00076.22 OAG20912.1 - 4.5e-80 263.5 4.2 4.4e-19 68.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAG20912.1 - 6.1e-27 93.6 0.4 6.1e-27 93.6 0.4 2.8 3 1 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAG20912.1 - 3e-10 39.8 1.2 0.0062 16.1 0.0 4.6 3 2 2 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG20912.1 - 0.00053 19.8 0.1 1.2 9.0 0.0 3.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG20912.1 - 0.0024 18.0 0.1 9 6.5 0.0 4.8 5 1 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 OAG20912.1 - 0.0035 17.4 0.0 23 5.2 0.0 3.5 3 0 0 3 3 3 0 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.6 OAG20912.1 - 0.0082 16.1 0.4 37 4.4 0.0 4.1 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG20912.1 - 0.019 15.0 15.3 7.3 6.7 1.5 5.4 4 1 1 5 5 5 0 RNA binding motif OB_RNB PF08206.11 OAG20912.1 - 0.038 13.7 1.5 17 5.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 OAG20912.1 - 0.043 14.3 5.4 1.7 9.2 0.4 3.0 3 0 0 3 3 3 0 Heat induced stress protein YflT DbpA PF03880.15 OAG20912.1 - 0.13 12.3 0.1 54 3.9 0.0 3.7 4 0 0 4 4 4 0 DbpA RNA binding domain HNOBA PF07701.14 OAG20912.1 - 0.55 9.6 3.4 0.43 10.0 1.6 1.8 1 1 0 1 1 1 0 Heme NO binding associated FBPase PF00316.20 OAG20913.1 - 6.4e-70 234.5 0.1 8.9e-70 234.0 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Transket_pyr PF02779.24 OAG20915.1 - 3.8e-64 215.6 0.0 7.9e-64 214.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OAG20915.1 - 1e-58 197.4 0.1 2e-58 196.4 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 OAG20915.1 - 8.6e-56 189.1 0.0 1.3e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 OAG20915.1 - 5.6e-18 64.3 2.6 1e-17 63.4 2.6 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus BSD PF03909.17 OAG20916.1 - 6.4e-23 80.5 12.6 9.4e-14 51.2 0.1 4.0 5 0 0 5 5 5 2 BSD domain PH_TFIIH PF08567.11 OAG20916.1 - 2e-18 66.5 0.0 4.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF1992 PF09350.10 OAG20919.1 - 6.9e-19 67.8 0.1 1.8e-18 66.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF4121 PF13497.6 OAG20919.1 - 0.058 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) RRF PF01765.19 OAG20920.1 - 6.7e-31 107.4 0.0 8.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Polysacc_deac_1 PF01522.21 OAG20921.1 - 3.6e-26 91.5 0.0 6.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase UDPG_MGDP_dh PF00984.19 OAG20921.1 - 2.5e-18 66.1 0.0 5.5e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 OAG20921.1 - 3.9e-17 62.4 0.1 4.3e-15 55.8 0.1 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 OAG20921.1 - 0.00038 20.7 0.1 0.001 19.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 OAG20921.1 - 0.01 16.3 0.0 0.051 14.0 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Chitin_synth_2 PF03142.15 OAG20922.1 - 1.1e-33 116.8 6.9 8.8e-26 90.6 0.4 3.5 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG20922.1 - 7.9e-06 25.9 1.1 7.9e-06 25.9 1.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG20922.1 - 0.00092 19.1 0.1 0.52 10.1 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG20922.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Guanylate_cyc_2 PF09778.9 OAG20924.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase RTA1 PF04479.13 OAG20925.1 - 5.2e-39 134.0 11.4 7.7e-39 133.4 11.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3176 PF11374.8 OAG20926.1 - 3.5e-24 85.1 3.0 3.5e-24 85.1 3.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3176 PF11374.8 OAG20927.1 - 4.1e-29 100.9 1.4 4.5e-29 100.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2569 PF10754.9 OAG20927.1 - 0.068 13.6 2.9 0.56 10.6 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Transferase PF02458.15 OAG20928.1 - 6.2e-32 110.8 0.0 1.3e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Transferase family Zn_clus PF00172.18 OAG20929.1 - 1.4e-07 31.5 8.5 4e-07 30.1 8.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG20929.1 - 0.026 13.6 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pep1_7 PF17232.2 OAG20930.1 - 0.025 15.0 0.3 0.039 14.4 0.3 1.4 1 0 0 1 1 1 0 Elicitor peptide 1-7 DUF1925 PF09094.11 OAG20930.1 - 0.14 12.5 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Glyco_hydro_61 PF03443.14 OAG20931.1 - 8.1e-59 199.0 0.2 1.3e-58 198.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG20931.1 - 6.1e-05 22.9 7.6 0.00022 21.1 7.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Methyltransf_16 PF10294.9 OAG20932.1 - 0.045 13.5 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Proteasome PF00227.26 OAG20933.1 - 1.8e-31 109.1 0.0 4.6e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.13 OAG20934.1 - 1.2e-28 99.6 0.3 1.9e-28 99.0 0.3 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 OAG20935.1 - 2e-28 99.2 0.0 2.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Epimerase PF01370.21 OAG20936.1 - 2.6e-21 76.2 0.0 5.4e-21 75.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG20936.1 - 2.9e-12 46.6 0.0 6.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG20936.1 - 9e-09 34.7 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG20936.1 - 3.5e-06 26.3 0.0 5.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG20936.1 - 8.9e-05 21.8 0.0 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 OAG20936.1 - 0.0017 18.3 0.0 0.007 16.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG20936.1 - 0.024 13.8 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ABC2_membrane PF01061.24 OAG20937.1 - 2.4e-89 298.3 60.3 6e-46 156.5 16.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG20937.1 - 1.3e-36 126.2 0.2 1.7e-17 64.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG20937.1 - 1.5e-32 111.3 1.7 2e-26 91.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG20937.1 - 1.7e-18 67.0 0.3 5.7e-18 65.3 0.3 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG20937.1 - 2.8e-07 31.1 0.1 0.002 18.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG20937.1 - 6.6e-07 29.4 0.2 0.025 14.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG20937.1 - 4.9e-06 26.6 0.3 0.00015 21.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG20937.1 - 1.1e-05 25.0 0.7 0.057 13.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG20937.1 - 1.4e-05 25.1 0.6 0.0054 16.8 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG20937.1 - 0.00011 22.7 1.2 0.074 13.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 OAG20937.1 - 0.00012 22.4 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 OAG20937.1 - 0.00026 20.2 13.4 0.00026 20.2 13.4 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.6 OAG20937.1 - 0.0007 19.8 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG20937.1 - 0.0022 18.3 0.0 0.009 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG20937.1 - 0.0022 17.6 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 OAG20937.1 - 0.0043 16.5 5.1 0.055 12.9 0.1 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 OAG20937.1 - 0.0056 16.1 0.3 1.6 8.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 OAG20937.1 - 0.024 14.2 0.2 0.41 10.2 0.1 2.8 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 OAG20937.1 - 0.024 14.6 0.0 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 OAG20937.1 - 0.027 14.4 0.1 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Septin PF00735.18 OAG20937.1 - 0.039 13.2 0.2 0.32 10.2 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 OAG20937.1 - 0.057 13.1 0.1 38 3.8 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 OAG20937.1 - 0.066 12.5 0.4 0.44 9.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 OAG20937.1 - 0.068 12.9 0.1 0.98 9.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 OAG20937.1 - 0.075 12.2 0.2 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF4869 PF16163.5 OAG20937.1 - 0.1 12.3 0.1 0.43 10.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) G-alpha PF00503.20 OAG20937.1 - 0.16 11.1 0.3 4.5 6.3 0.2 2.8 2 1 0 2 2 2 0 G-protein alpha subunit T2SSE PF00437.20 OAG20937.1 - 0.18 10.9 0.0 5.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OAG20937.1 - 0.38 10.5 4.9 4.5 6.9 0.2 2.8 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 OAG20937.1 - 0.96 9.5 6.9 0.12 12.5 0.4 2.6 3 0 0 3 3 3 0 Dynamin family NAD_Gly3P_dh_C PF07479.14 OAG20938.1 - 1.7e-45 154.8 0.1 2.7e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OAG20938.1 - 5.6e-45 153.1 0.0 1.5e-44 151.8 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BUD22 PF09073.10 OAG20939.1 - 0.085 12.2 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.13 OAG20939.1 - 0.84 7.6 6.8 0.87 7.6 6.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 OAG20939.1 - 4.3 5.5 5.0 4.4 5.5 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_4 PF07993.12 OAG20940.1 - 6.2e-42 143.5 0.0 9.2e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG20940.1 - 9e-26 90.4 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG20940.1 - 5.1e-09 36.4 0.0 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAG20940.1 - 8e-09 35.3 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG20940.1 - 0.0019 17.3 0.0 0.028 13.4 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF776 PF05604.11 OAG20940.1 - 0.13 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) Semialdhyde_dh PF01118.24 OAG20940.1 - 0.17 12.3 0.1 0.43 11.0 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAG20941.1 - 1.4e-40 139.3 48.9 1.4e-40 139.3 48.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Ntox10 PF15520.6 OAG20941.1 - 0.033 14.1 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Novel toxin 10 C2 PF00168.30 OAG20942.1 - 1.5e-09 38.0 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Taxilin PF09728.9 OAG20943.1 - 0.48 9.5 5.7 2.6 7.1 0.5 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Ank_2 PF12796.7 OAG20944.1 - 1.2e-30 105.9 5.8 1.2e-12 48.2 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OAG20944.1 - 1e-15 57.4 0.8 0.089 13.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OAG20944.1 - 1.7e-15 57.1 0.1 0.0008 19.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG20944.1 - 2.3e-14 52.0 0.0 0.032 14.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG20944.1 - 5.9e-14 51.9 0.9 0.014 15.7 0.2 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) MFS_1 PF07690.16 OAG20945.1 - 5.6e-49 167.0 38.1 5.6e-49 167.0 38.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG20945.1 - 3.4e-14 52.6 2.0 3.4e-14 52.6 2.0 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter MDM31_MDM32 PF08118.11 OAG20947.1 - 4.9e-245 814.2 2.4 6.6e-245 813.7 2.4 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 OAG20948.1 - 7.3e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAG20948.1 - 0.027 14.3 1.0 0.049 13.5 1.0 1.4 1 0 0 1 1 1 0 KH domain Diphthami_syn_2 PF01902.17 OAG20949.1 - 4.4e-27 95.0 0.0 7.3e-26 91.0 0.0 2.1 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAG20949.1 - 7.9e-15 54.9 0.0 6.1e-09 35.9 0.0 3.9 3 1 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 OAG20950.1 - 1.5e-12 47.3 14.2 6.1e-07 29.5 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG20950.1 - 2.1e-08 34.3 11.5 0.00037 21.1 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG20950.1 - 3.7e-06 27.1 5.1 0.011 16.0 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG20950.1 - 2.7e-05 24.4 14.9 8.7e-05 22.8 6.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 OAG20950.1 - 2.9e-05 24.3 4.7 0.0058 17.0 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 OAG20950.1 - 0.0049 16.5 3.3 1.6 8.4 0.2 2.4 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 OAG20950.1 - 0.01 15.8 11.8 0.11 12.5 1.3 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 OAG20950.1 - 0.016 15.1 9.0 0.1 12.6 0.7 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-UBR PF02207.20 OAG20950.1 - 0.11 12.7 1.7 0.27 11.4 1.7 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LIM PF00412.22 OAG20950.1 - 0.17 12.2 2.9 0.53 10.6 3.0 1.9 1 1 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 OAG20950.1 - 0.19 11.5 9.3 1.3 8.8 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 OAG20950.1 - 0.2 12.4 4.0 2.4 8.9 0.6 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 OAG20950.1 - 0.48 10.3 3.3 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2HE PF16278.5 OAG20950.1 - 1.7 9.2 7.0 1.6e+02 2.8 7.0 2.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 OAG20950.1 - 2.6 8.3 7.0 4.9 7.4 0.5 3.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-BED PF02892.15 OAG20950.1 - 6.2 6.9 7.5 4.1 7.5 3.4 2.4 1 1 1 2 2 2 0 BED zinc finger SNF2_N PF00176.23 OAG20952.1 - 3.9e-69 233.0 0.2 5.4e-69 232.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAG20952.1 - 2.1e-18 66.0 0.0 5.4e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAG20952.1 - 5.4e-14 52.5 0.0 3.3e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 OAG20952.1 - 3.2e-10 39.7 12.4 5.9e-10 38.8 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG20952.1 - 4.6e-10 39.2 9.1 9.1e-10 38.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG20952.1 - 4.4e-09 36.1 13.1 7.9e-09 35.3 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG20952.1 - 2.2e-08 34.3 11.4 4.1e-08 33.4 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG20952.1 - 1.6e-07 31.2 10.1 3.7e-07 30.1 10.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG20952.1 - 4.7e-07 29.7 9.7 8.3e-07 28.9 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 OAG20952.1 - 8.1e-07 29.2 0.1 3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 OAG20952.1 - 4.1e-06 26.8 12.2 7.4e-06 26.0 12.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG20952.1 - 2.4e-05 24.1 8.9 4.7e-05 23.2 8.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG20952.1 - 0.00042 20.5 9.7 0.0013 19.0 9.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAG20952.1 - 0.00069 19.4 2.3 0.0014 18.4 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OAG20952.1 - 0.04 14.0 4.7 0.11 12.6 4.6 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OAG20952.1 - 0.041 13.7 9.3 0.14 12.0 9.4 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Pterin_bind PF00809.22 OAG20952.1 - 0.055 13.1 1.3 0.8 9.3 0.6 2.6 3 0 0 3 3 3 0 Pterin binding enzyme zf-RING_4 PF14570.6 OAG20952.1 - 0.14 12.0 9.3 1 9.2 9.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 OAG20952.1 - 0.32 11.1 4.0 0.68 10.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 OAG20952.1 - 0.37 10.6 6.0 1 9.2 6.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 OAG20952.1 - 0.93 9.5 6.1 1.7 8.7 6.1 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 OAG20952.1 - 1.1 9.5 6.5 2.4 8.3 6.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Histone_HNS PF00816.21 OAG20952.1 - 5.2 8.0 8.9 20 6.1 3.6 3.2 3 0 0 3 3 2 0 H-NS histone family DUF5518 PF17647.1 OAG20953.1 - 0.0038 17.4 0.1 0.0049 17.0 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5518) PPTA PF01239.22 OAG20954.1 - 1.5e-39 132.6 23.2 6.1e-10 38.5 0.8 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 OAG20954.1 - 0.081 13.3 0.1 6.4 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4219 PF13961.6 OAG20954.1 - 4.9 6.9 8.9 3.2 7.5 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) PALP PF00291.25 OAG20955.1 - 2.6e-65 220.7 0.1 4.1e-65 220.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TIR_3 PF18567.1 OAG20955.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain DUF2700 PF10912.8 OAG20958.1 - 0.00017 21.7 2.5 0.14 12.2 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2700) Cation_efflux PF01545.21 OAG20958.1 - 0.016 14.9 4.9 0.042 13.6 4.9 1.7 1 1 0 1 1 1 0 Cation efflux family MARVEL PF01284.23 OAG20958.1 - 0.029 14.4 12.4 0.042 13.9 11.6 1.8 1 1 1 2 2 2 0 Membrane-associating domain OATP PF03137.20 OAG20958.1 - 0.043 12.1 0.6 0.076 11.3 0.4 1.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF588 PF04535.12 OAG20958.1 - 0.064 13.0 4.0 0.094 12.5 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) YqgB PF11036.8 OAG20958.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Virulence promoting factor SUa-2TM PF18179.1 OAG20958.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF3290 PF11694.8 OAG20958.1 - 0.3 11.1 1.7 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Vpu PF00558.19 OAG20958.1 - 0.76 9.6 6.2 11 5.8 1.2 2.8 2 1 1 3 3 3 0 Vpu protein DUF4381 PF14316.6 OAG20958.1 - 1.6 8.9 3.9 18 5.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LPG_synthase_TM PF03706.13 OAG20958.1 - 2.1 7.8 10.3 1 8.9 5.7 2.0 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF2157 PF09925.9 OAG20958.1 - 2.8 7.7 8.4 2 8.2 5.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) 7TMR-DISM_7TM PF07695.11 OAG20958.1 - 2.9 7.7 10.3 0.37 10.7 6.0 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling Tetraspanin PF00335.20 OAG20958.1 - 8.6 6.0 11.0 73 3.0 11.0 2.2 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 OAG20958.1 - 9.3 6.8 10.7 39 4.8 7.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ribosomal_L5_C PF00673.21 OAG20959.1 - 7.2e-23 80.6 0.0 1.1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG20959.1 - 2.5e-20 72.5 0.0 7.3e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 OAG20960.1 - 3.6e-18 65.0 0.1 4.7e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 OAG20961.1 - 6.6e-34 116.4 0.0 8.1e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers AAA PF00004.29 OAG20962.1 - 3.1e-53 179.7 0.0 2.8e-43 147.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAG20962.1 - 1.2e-27 96.1 0.6 1.2e-27 96.1 0.6 1.9 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAG20962.1 - 2.4e-14 52.8 0.0 2.4e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG20962.1 - 2.9e-07 31.0 10.3 0.017 15.5 0.1 5.1 4 2 2 6 6 5 2 AAA ATPase domain AAA_2 PF07724.14 OAG20962.1 - 5.7e-07 29.8 0.0 0.076 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 OAG20962.1 - 7.5e-06 25.6 0.0 0.00033 20.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OAG20962.1 - 1.4e-05 25.3 0.9 0.095 13.0 0.0 3.7 2 2 1 3 3 3 2 AAA domain NACHT PF05729.12 OAG20962.1 - 2.3e-05 24.4 1.0 0.039 13.9 0.0 3.9 4 1 0 4 4 3 1 NACHT domain TsaE PF02367.17 OAG20962.1 - 5e-05 23.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAG20962.1 - 9e-05 23.0 0.1 2.5 8.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 OAG20962.1 - 0.00018 21.3 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG20962.1 - 0.00027 21.0 0.1 1.2 9.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 OAG20962.1 - 0.00037 20.6 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 OAG20962.1 - 0.0013 18.5 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAG20962.1 - 0.0015 17.8 0.0 0.54 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 OAG20962.1 - 0.0018 18.0 0.0 0.24 11.1 0.0 3.1 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAG20962.1 - 0.0036 17.5 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG20962.1 - 0.0079 16.6 0.0 5.3 7.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAG20962.1 - 0.0095 16.0 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG20962.1 - 0.027 14.9 0.8 2.3 8.6 0.1 3.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAG20962.1 - 0.033 14.7 0.8 13 6.3 0.0 3.2 3 0 0 3 3 2 0 ABC transporter Mg_chelatase PF01078.21 OAG20962.1 - 0.054 12.9 0.2 0.77 9.1 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAG20962.1 - 0.071 13.3 0.1 19 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAG20962.1 - 0.079 12.5 5.4 1.4 8.4 0.1 3.8 3 2 2 5 5 5 0 AAA domain TIP49 PF06068.13 OAG20962.1 - 0.098 11.8 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_10 PF12846.7 OAG20962.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Cytidylate_kin2 PF13189.6 OAG20962.1 - 0.15 12.2 0.0 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family PEX-2N PF09263.10 OAG20962.1 - 0.27 11.6 1.2 11 6.4 0.1 3.1 3 0 0 3 3 2 0 Peroxisome biogenesis factor 1, N-terminal MCM PF00493.23 OAG20963.1 - 1.1e-103 345.2 0.0 1.6e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG20963.1 - 3.1e-32 111.1 0.4 5.5e-32 110.3 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OAG20963.1 - 3e-19 69.5 1.0 7.1e-19 68.3 1.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 OAG20963.1 - 1.5e-17 63.8 0.3 3.5e-17 62.6 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OAG20963.1 - 2.8e-07 30.2 0.0 2.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG20963.1 - 4.4e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OAG20963.1 - 0.0016 18.2 0.1 0.0058 16.4 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 OAG20963.1 - 0.018 15.7 1.9 0.034 14.8 0.4 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 OAG20963.1 - 0.024 14.5 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG20963.1 - 0.11 12.2 0.0 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SHR3_chaperone PF08229.11 OAG20964.1 - 5.3e-73 244.0 0.1 6e-73 243.8 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 OAG20964.1 - 0.35 10.8 5.8 0.1 12.6 0.6 2.3 1 1 1 3 3 3 0 Family of unknown function (DUF5453) RRM_1 PF00076.22 OAG20965.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldh_1_N PF00056.23 OAG20966.1 - 9.9e-34 116.4 0.0 1.5e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG20966.1 - 9.1e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 OAG20966.1 - 0.0035 17.9 0.5 0.0097 16.5 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG20966.1 - 0.0059 16.3 0.2 0.013 15.2 0.2 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAG20966.1 - 0.011 15.9 0.2 0.021 15.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 OAG20966.1 - 0.084 12.4 1.4 5.6 6.4 0.2 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase HBS1_N PF08938.10 OAG20966.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus Peptidase_M19 PF01244.21 OAG20967.1 - 5.8e-100 334.5 0.0 6.7e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 OAG20967.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Ilm1 PF10311.9 OAG20968.1 - 7.8e-56 188.2 1.8 8.9e-56 188.1 1.8 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Tyrosinase PF00264.20 OAG20969.1 - 1e-43 150.2 1.4 2.3e-43 149.0 1.4 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase YrvL PF14184.6 OAG20970.1 - 0.55 10.3 8.4 0.1 12.7 4.2 1.9 2 0 0 2 2 2 0 Regulatory protein YrvL MOSC PF03473.17 OAG20972.1 - 2.5e-35 121.3 0.0 5.8e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG20972.1 - 5.1e-24 84.4 0.0 1.1e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OAG20972.1 - 8.4e-23 80.9 0.0 5.1e-22 78.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DUF1780 PF08682.10 OAG20974.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) DUF1388 PF07142.12 OAG20974.1 - 0.45 10.5 17.7 0.8 9.7 3.4 4.6 5 0 0 5 5 5 0 Repeat of unknown function (DUF1388) Ecm29 PF13001.7 OAG20975.1 - 9.1e-163 542.5 2.1 1.4e-162 541.8 0.1 2.3 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 OAG20975.1 - 3.8e-08 32.9 2.3 1.3 9.5 0.1 8.3 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 OAG20975.1 - 2.3e-06 28.1 0.2 0.064 13.9 0.1 5.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG20975.1 - 0.00096 19.6 0.8 81 3.9 0.0 6.3 6 0 0 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 OAG20975.1 - 0.096 12.2 0.0 3 7.3 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal IFRD PF05004.13 OAG20975.1 - 0.11 11.6 3.9 2.6 7.0 0.0 4.3 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Retrotran_gag_2 PF14223.6 OAG20975.1 - 0.13 11.9 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Thioredoxin_7 PF13899.6 OAG20976.1 - 2e-17 63.2 0.1 7e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 OAG20976.1 - 3e-15 55.7 0.0 7.8e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAG20976.1 - 9.4e-08 32.2 0.0 3.1e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 OAG20976.1 - 0.0075 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain UBA_4 PF14555.6 OAG20977.1 - 6.5e-06 25.9 0.4 1.8e-05 24.5 0.4 1.8 1 0 0 1 1 1 1 UBA-like domain SnoaL_4 PF13577.6 OAG20978.1 - 2.9e-26 92.1 0.0 3.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.8 OAG20978.1 - 0.002 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) Lumazine_bd_2 PF12893.7 OAG20978.1 - 0.0041 17.8 0.0 0.011 16.4 0.0 1.7 1 1 1 2 2 2 1 Putative lumazine-binding DUF4440 PF14534.6 OAG20978.1 - 0.025 15.0 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAG20978.1 - 0.039 14.6 0.0 0.084 13.5 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.12 OAG20978.1 - 0.098 12.5 0.0 0.31 10.8 0.0 1.8 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase p450 PF00067.22 OAG20979.1 - 1.7e-52 178.7 0.0 4e-52 177.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF4148 PF13663.6 OAG20979.1 - 0.024 14.8 0.1 0.71 10.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Glyco_hydro_10 PF00331.20 OAG20980.1 - 2.9e-98 328.9 0.8 3.3e-98 328.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Linocin_M18 PF04454.12 OAG20980.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase DUF3995 PF13160.6 OAG20981.1 - 0.012 16.0 0.5 0.014 15.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4499 PF14934.6 OAG20981.1 - 0.022 15.0 1.0 0.028 14.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) DMT_YdcZ PF04657.13 OAG20981.1 - 3 8.1 6.7 0.16 12.2 1.6 1.4 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ FAD_binding_3 PF01494.19 OAG20982.1 - 1.4e-12 47.6 0.0 3.7e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG20982.1 - 1.6e-05 24.7 0.1 5.3e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG20982.1 - 6.7e-05 22.3 0.2 0.046 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG20982.1 - 0.0021 18.3 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PFEMP PF03011.15 OAG20982.1 - 0.013 16.2 0.1 0.021 15.5 0.1 1.3 1 0 0 1 1 1 0 PFEMP DBL domain Trp_halogenase PF04820.14 OAG20982.1 - 0.031 13.1 0.2 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG20982.1 - 0.032 14.2 0.0 0.94 9.5 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG20982.1 - 0.14 12.7 0.1 7.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG20982.1 - 0.14 11.2 0.3 0.22 10.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain ATP-synt_S1 PF05827.12 OAG20983.1 - 0.097 12.5 2.3 0.15 11.9 0.7 1.9 1 1 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) R3H PF01424.22 OAG20984.1 - 7.5e-16 57.9 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 OAG20984.1 - 3.7e-08 33.3 83.8 8.7e-05 22.5 16.3 13.2 14 0 0 14 14 14 7 NF-X1 type zinc finger BSP_II PF05432.11 OAG20984.1 - 0.2 11.3 8.1 0.34 10.6 8.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_L_2 PF13656.6 OAG20985.1 - 2.8e-24 84.7 0.0 4.2e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG20985.1 - 5.7e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Myb_DNA-bind_6 PF13921.6 OAG20986.1 - 2.2e-13 50.2 0.7 2.2e-13 50.2 0.7 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 OAG20986.1 - 9.5e-13 48.3 0.5 9.5e-13 48.3 0.5 4.0 5 0 0 5 5 5 1 HSA Myb_DNA-binding PF00249.31 OAG20986.1 - 0.0004 20.5 0.7 0.0013 18.9 0.7 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain HemY_N PF07219.13 OAG20986.1 - 0.17 12.1 1.6 0.94 9.7 1.6 2.3 1 0 0 1 1 1 0 HemY protein N-terminus DNA_pol_D_N PF18018.1 OAG20986.1 - 0.19 11.8 0.9 0.76 9.9 0.9 2.1 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 OAG20987.1 - 1.2e-10 41.7 0.0 0.3 12.0 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAG20987.1 - 0.00013 20.9 0.1 0.084 11.6 0.0 3.0 1 1 2 3 3 3 3 Nup133 N terminal like HrcA PF01628.21 OAG20987.1 - 0.13 12.1 0.0 6.4 6.6 0.0 2.3 2 0 0 2 2 2 0 HrcA protein C terminal domain AA_permease PF00324.21 OAG20988.1 - 6.7e-59 199.7 29.7 8.4e-59 199.4 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAG20988.1 - 1.1e-22 80.7 8.4 1.4e-10 40.8 0.0 4.0 4 0 0 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 OAG20988.1 - 1.3e-19 70.3 37.9 1.9e-19 69.8 37.9 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 OAG20989.1 - 9.4e-84 281.5 32.3 1.1e-83 281.2 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ac81 PF05820.11 OAG20989.1 - 0.48 10.0 5.9 0.94 9.0 5.9 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 SIS PF01380.22 OAG20991.1 - 4.4e-57 191.6 0.0 8e-31 106.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAG20991.1 - 9e-17 61.5 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG20991.1 - 1.3e-10 41.2 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAG20991.1 - 0.00073 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 OAG20991.1 - 0.038 14.0 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 SIS domain Holin_BhlA PF10960.8 OAG20991.1 - 0.14 12.2 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 BhlA holin family DMRL_synthase PF00885.19 OAG20992.1 - 4.4e-56 188.6 0.0 5.9e-56 188.2 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase N-SET PF11764.8 OAG20993.1 - 8.4e-54 182.3 8.0 8.4e-54 182.3 8.0 3.6 4 0 0 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 OAG20993.1 - 7.5e-27 92.8 2.1 9e-27 92.5 0.7 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 OAG20993.1 - 1.5e-19 71.0 0.1 1.5e-19 71.0 0.1 3.9 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 OAG20993.1 - 0.00046 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EXS PF03124.14 OAG20995.1 - 4.7e-111 371.3 6.9 5.4e-111 371.1 6.9 1.0 1 0 0 1 1 1 1 EXS family CHDCT2 PF08074.11 OAG20995.1 - 0.14 12.3 0.1 0.22 11.7 0.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain 4HBT_3 PF13622.6 OAG20997.1 - 1.4e-53 182.7 0.0 1.6e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAG20997.1 - 0.005 17.2 0.5 0.023 15.0 0.2 2.0 2 0 0 2 2 2 1 Thioesterase superfamily AMP-binding PF00501.28 OAG20998.1 - 1.9e-100 336.4 0.0 2.3e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG20998.1 - 3.3e-14 53.6 0.0 8.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L36e PF01158.18 OAG21000.1 - 8.5e-40 134.9 3.5 9.7e-40 134.7 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 OAG21000.1 - 0.11 12.6 1.2 0.14 12.3 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PITH PF06201.13 OAG21001.1 - 1.1e-39 136.1 0.2 1.7e-38 132.2 0.0 2.1 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 OAG21001.1 - 1.7e-16 60.1 0.0 3.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 OAG21001.1 - 0.00039 20.4 0.1 0.00061 19.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OAG21001.1 - 0.0042 17.5 0.1 0.009 16.4 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG21001.1 - 0.032 14.6 0.2 1.5 9.2 0.1 2.3 1 1 1 2 2 2 0 Thioredoxin-like DIM1 PF02966.16 OAG21001.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 TUG-UBL1 PF11470.8 OAG21002.1 - 6.4e-25 87.2 0.4 1.4e-23 82.8 0.1 2.9 3 0 0 3 3 3 1 TUG ubiquitin-like domain UBX PF00789.20 OAG21002.1 - 8.5e-10 38.7 0.0 5.4e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 UBX domain ubiquitin PF00240.23 OAG21002.1 - 0.0084 15.8 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DraK_HK_N PF18092.1 OAG21002.1 - 4.5 7.8 6.5 16 6.0 0.0 2.8 3 0 0 3 3 3 0 DraK Histidine Kinase N-terminal domain Spc7 PF08317.11 OAG21003.1 - 0.00072 18.5 17.4 0.00072 18.5 17.4 3.3 1 1 2 3 3 3 1 Spc7 kinetochore protein KASH_CCD PF14662.6 OAG21003.1 - 0.058 13.2 43.7 0.056 13.3 25.2 3.6 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF3287 PF11690.8 OAG21003.1 - 0.97 9.2 4.7 1.4 8.7 1.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DASH_Dam1 PF08653.10 OAG21003.1 - 3.9 7.3 4.4 11 5.9 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 OAG21003.1 - 6.5 7.2 9.8 14 6.2 0.7 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 OAG21004.1 - 0.0027 17.9 5.5 0.036 14.3 0.1 3.1 1 1 2 3 3 3 1 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 OAG21004.1 - 0.0041 16.9 3.6 0.037 13.9 0.0 3.5 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat DNA_repr_REX1B PF14966.6 OAG21004.1 - 0.0052 17.4 2.3 2.5 8.8 0.6 2.6 1 1 1 2 2 2 2 DNA repair REX1-B Mer2 PF09074.10 OAG21004.1 - 0.0068 16.2 5.3 0.012 15.4 4.8 1.5 1 1 0 1 1 1 1 Mer2 DUF4094 PF13334.6 OAG21004.1 - 0.016 15.6 2.9 1.7 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Imm41 PF15592.6 OAG21004.1 - 0.04 14.3 0.3 0.17 12.3 0.1 2.2 1 1 1 2 2 2 0 Immunity protein 41 MyTH4 PF00784.17 OAG21004.1 - 0.044 14.3 0.4 0.084 13.4 0.4 1.7 1 1 0 1 1 1 0 MyTH4 domain Med9 PF07544.13 OAG21004.1 - 0.21 11.7 4.0 4.7 7.4 0.1 3.1 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-C3HC4_4 PF15227.6 OAG21005.1 - 1.3e-05 25.2 12.0 1.3e-05 25.2 12.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG21005.1 - 2e-05 24.3 18.5 5.4e-05 22.9 11.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG21005.1 - 3.6e-05 24.0 17.7 0.00012 22.4 11.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG21005.1 - 0.00013 21.7 9.5 0.00013 21.7 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG21005.1 - 0.00014 21.7 11.7 0.00014 21.7 11.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG21005.1 - 0.0012 18.8 8.7 0.0012 18.8 8.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG21005.1 - 0.0014 18.6 11.4 0.0014 18.6 11.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG21005.1 - 0.035 14.0 9.4 0.24 11.3 7.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAG21005.1 - 0.66 10.1 8.1 1.3 9.2 8.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OAG21005.1 - 1.5 8.9 8.7 0.27 11.3 2.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG21005.1 - 7 7.0 13.0 1.5 9.2 8.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain CHCH PF06747.13 OAG21007.1 - 2.1e-05 24.5 3.0 3.7e-05 23.7 3.0 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 OAG21007.1 - 0.001 19.2 2.4 0.0014 18.8 2.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 OAG21007.1 - 0.12 12.6 2.8 0.21 11.9 2.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 OAG21007.1 - 0.23 11.5 4.6 0.39 10.8 4.6 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like FKBP_C PF00254.28 OAG21008.1 - 2.2e-27 95.2 0.0 2.6e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF983 PF06170.12 OAG21010.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) M20_dimer PF07687.14 OAG21012.1 - 1.1e-19 70.3 0.0 2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAG21012.1 - 1.2e-16 61.0 0.3 1.1e-15 57.9 0.3 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAG21012.1 - 4.1e-05 23.4 0.0 9.1e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Chordopox_A33R PF05966.12 OAG21012.1 - 0.27 10.5 1.5 7.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein M16C_assoc PF08367.11 OAG21013.1 - 3.6e-87 291.7 0.6 5.6e-87 291.0 0.6 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OAG21013.1 - 3.7e-27 95.5 0.0 2.5e-21 76.5 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG21013.1 - 1.3e-07 31.7 0.1 6.5e-06 26.2 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Tim29 PF10171.9 OAG21013.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 TYW3 PF02676.14 OAG21013.1 - 0.062 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 NMO PF03060.15 OAG21014.1 - 1.2e-52 179.4 1.0 1.6e-52 178.9 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG21014.1 - 1.7e-10 40.4 2.3 7e-10 38.4 2.3 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG21014.1 - 7.2e-05 22.0 1.6 0.00012 21.2 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FATC PF02260.20 OAG21014.1 - 0.011 15.5 0.1 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 FATC domain PEP_hydrolase PF09370.10 OAG21014.1 - 0.051 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Pkinase PF00069.25 OAG21015.1 - 4.1e-67 226.3 0.0 6.1e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21015.1 - 3.8e-42 144.4 0.0 5.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG21015.1 - 4.1e-08 32.9 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG21015.1 - 3.2e-05 23.0 0.2 3.2e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG21015.1 - 0.011 15.7 3.9 0.068 13.1 0.2 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG21015.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAG21015.1 - 0.03 13.7 0.5 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAG21015.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.2 2 1 1 3 3 3 0 RIO1 family AA_permease PF00324.21 OAG21016.1 - 2.5e-145 484.8 30.4 2.8e-145 484.6 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG21016.1 - 7.6e-38 130.4 31.4 9.4e-38 130.1 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease T_cell_tran_alt PF15128.6 OAG21016.1 - 2 8.3 4.1 0.86 9.5 0.1 2.4 2 1 1 3 3 3 0 T-cell leukemia translocation-altered Aldo_ket_red PF00248.21 OAG21017.1 - 3.6e-40 138.0 0.0 2.9e-29 102.2 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family P3A PF08727.11 OAG21017.1 - 0.1 12.0 0.7 0.22 10.9 0.7 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like Pigment_DH PF06324.11 OAG21017.1 - 0.72 10.1 0.1 0.72 10.1 0.1 2.0 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) tRNA-synt_1d PF00750.19 OAG21020.1 - 2.6e-65 220.7 0.5 5.1e-64 216.4 0.5 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG21020.1 - 1.7e-09 37.9 0.1 4e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Transpeptidase PF00905.22 OAG21020.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Period_C PF12114.8 OAG21022.1 - 3.4 7.2 10.9 6.8 6.2 10.9 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Syntaxin-6_N PF09177.11 OAG21023.1 - 0.13 12.9 10.3 0.19 12.3 2.3 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 OAG21023.1 - 0.25 11.4 11.6 0.059 13.5 2.8 2.3 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 OAG21023.1 - 0.3 11.2 16.6 4.9 7.2 7.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein KIP1 PF07765.12 OAG21023.1 - 2.1 8.5 7.8 16 5.7 1.7 2.9 1 1 0 2 2 2 0 KIP1-like protein DUF724 PF05266.14 OAG21023.1 - 8.3 6.2 10.2 1.2 8.9 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Comm PF15957.5 OAG21024.1 - 0.0023 18.3 0.4 0.016 15.5 0.2 2.2 2 1 0 2 2 2 1 Commissureless DUF1385 PF07136.11 OAG21024.1 - 0.006 15.9 3.0 0.0082 15.5 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) DUF2721 PF11026.8 OAG21024.1 - 0.27 11.1 6.5 0.37 10.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Fungal_trans PF04082.18 OAG21025.1 - 5.8e-23 81.3 0.0 1.3e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21025.1 - 0.00088 19.3 14.9 0.0017 18.4 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG21025.1 - 0.013 14.4 0.1 0.074 11.9 0.0 2.0 2 1 0 3 3 3 0 Fungal specific transcription factor domain DUF2556 PF10831.8 OAG21025.1 - 0.13 12.2 0.0 22 5.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) SR-25 PF10500.9 OAG21025.1 - 1 8.9 7.0 1.6 8.3 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Extensin_2 PF04554.13 OAG21025.1 - 1.4 9.0 10.7 4.9 7.3 10.7 1.9 1 0 0 1 1 1 0 Extensin-like region GFO_IDH_MocA PF01408.22 OAG21026.1 - 1.2e-17 64.9 0.1 1.7e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG21026.1 - 0.019 15.6 0.0 0.031 14.9 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AMP-binding PF00501.28 OAG21027.1 - 1.7e-66 224.6 0.0 2.5e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG21027.1 - 3.6e-08 34.2 0.0 1.3e-07 32.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CorA PF01544.18 OAG21028.1 - 2e-15 56.9 0.4 4.7e-15 55.7 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CopD PF05425.13 OAG21028.1 - 0.0038 17.6 0.3 0.007 16.8 0.3 1.4 1 0 0 1 1 1 1 Copper resistance protein D MFS_1 PF07690.16 OAG21029.1 - 7.9e-27 94.1 39.8 7.9e-27 94.1 39.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PgaD PF13994.6 OAG21029.1 - 0.34 10.9 2.9 0.33 11.0 1.0 2.0 2 0 0 2 2 2 0 PgaD-like protein Acyl_transf_3 PF01757.22 OAG21030.1 - 0.039 13.0 34.2 0.18 10.9 34.2 2.2 1 1 0 1 1 1 0 Acyltransferase family Glyco_trans_2_3 PF13632.6 OAG21031.1 - 4.6e-23 82.2 5.6 4.6e-23 82.2 5.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG21031.1 - 4.2e-20 72.6 0.0 5.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG21031.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG21031.1 - 4.4e-06 26.6 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 OAG21032.1 - 9.1e-08 31.8 2.9 4.7e-07 29.5 2.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.22 OAG21032.1 - 1.2e-06 27.8 30.4 2.3e-06 27.0 30.4 1.4 1 0 0 1 1 1 1 Acyltransferase family Glycophorin_A PF01102.18 OAG21032.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A DAGAT PF03982.13 OAG21033.1 - 3.1e-95 318.5 0.0 4.1e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Stk19 PF10494.9 OAG21034.1 - 1.4e-83 280.3 0.0 2.1e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 TMV_coat PF00721.21 OAG21034.1 - 0.044 13.6 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) SWIM PF04434.17 OAG21036.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger Sugar_tr PF00083.24 OAG21038.1 - 1.6e-74 251.4 13.0 2.3e-72 244.3 13.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21038.1 - 3e-17 62.6 22.1 1.6e-13 50.3 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG21038.1 - 0.0023 18.0 7.4 0.0043 17.2 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 OAG21039.1 - 5.4e-116 387.8 1.1 9.8e-116 387.0 1.1 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAG21039.1 - 0.0027 16.9 0.1 0.0087 15.2 0.0 1.7 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Zn_clus PF00172.18 OAG21040.1 - 4e-07 30.0 11.7 6.9e-07 29.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG21040.1 - 0.04 13.0 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain UPF0029 PF01205.19 OAG21042.1 - 1.2e-20 73.8 0.1 7.9e-20 71.2 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 FdhE PF04216.12 OAG21042.1 - 3.7 7.3 6.1 1.8 8.4 3.7 1.6 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Ribosomal_L34 PF00468.17 OAG21043.1 - 5.5e-18 64.7 6.8 5.5e-18 64.7 6.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L34 Med19 PF10278.9 OAG21044.1 - 0.003 17.5 9.7 0.0037 17.2 9.7 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 OAG21044.1 - 8.3 6.2 12.9 10 5.9 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_M48_N PF16491.5 OAG21045.1 - 8.6e-62 208.3 6.2 8.6e-62 208.3 6.2 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAG21045.1 - 1.8e-44 151.9 0.0 3.1e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 OAG21045.1 - 0.00035 19.9 1.5 0.0076 15.5 1.3 2.7 2 1 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.6 OAG21045.1 - 0.026 14.3 0.8 0.075 12.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) SprT-like PF10263.9 OAG21045.1 - 0.048 13.5 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 OAG21045.1 - 0.071 13.0 0.1 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 IrrE N-terminal-like domain DUF2268 PF10026.9 OAG21045.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) FYVE PF01363.21 OAG21046.1 - 0.85 9.8 13.6 0.81 9.9 10.8 2.4 2 1 1 3 3 3 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 OAG21046.1 - 3.6 7.7 12.6 1.8 8.7 0.8 3.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger TRAP_alpha PF03896.16 OAG21048.1 - 0.0028 16.9 1.0 0.0031 16.8 0.4 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Comm PF15957.5 OAG21048.1 - 0.0074 16.6 0.2 0.2 12.0 0.2 2.1 1 1 0 1 1 1 1 Commissureless SKN1 PF03935.15 OAG21048.1 - 0.084 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) SID-1_RNA_chan PF13965.6 OAG21048.1 - 0.18 10.2 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4778 PF16008.5 OAG21048.1 - 0.41 10.7 6.4 0.48 10.4 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 OAG21048.1 - 4.2 6.0 5.9 5.4 5.7 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4360 PF14273.6 OAG21049.1 - 2.2e-41 141.7 0.1 2.7e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sugar_tr PF00083.24 OAG21050.1 - 4.2e-96 322.5 26.5 5e-96 322.3 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21050.1 - 1.7e-28 99.6 33.3 1.7e-28 99.6 33.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FKBP26_C PF18046.1 OAG21050.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 FKBP26_C-terminal DHDPS PF00701.22 OAG21051.1 - 3e-43 147.6 0.0 3.6e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 OAG21052.1 - 0.011 15.9 12.8 0.022 14.9 12.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG21053.1 - 8.2e-17 61.1 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21053.1 - 2.6e-09 37.0 13.2 3.8e-09 36.5 13.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG21054.1 - 2.1e-63 214.7 0.0 2.8e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4244 PF14029.6 OAG21054.1 - 0.063 12.7 0.0 0.063 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) FAD_binding_1 PF00667.20 OAG21055.1 - 5.5e-52 176.5 0.0 8.4e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG21055.1 - 9.9e-27 93.9 0.0 2.6e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG21055.1 - 1.9e-21 76.8 0.0 4.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FA_hydroxylase PF04116.13 OAG21056.1 - 1.3e-26 93.5 22.1 2.1e-25 89.6 21.0 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Sugar_tr PF00083.24 OAG21057.1 - 6.8e-100 335.1 35.1 7.9e-100 334.8 35.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21057.1 - 5.3e-32 111.1 33.4 5.3e-32 111.1 33.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PBP PF01161.20 OAG21059.1 - 2.8e-13 50.3 0.1 3.6e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PapD-like PF14874.6 OAG21059.1 - 0.13 12.5 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Flagellar-associated PapD-like PCI PF01399.27 OAG21060.1 - 4.9e-13 49.5 0.0 1.4e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 OAG21060.1 - 1.8e-11 43.5 2.2 1.8e-11 43.5 2.2 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix B1 PF02246.15 OAG21060.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein L b1 domain TPR_14 PF13428.6 OAG21060.1 - 0.041 14.7 0.4 0.21 12.5 0.4 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat ADK PF00406.22 OAG21061.1 - 6.1e-45 153.0 0.0 8.9e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG21061.1 - 3.6e-34 118.1 0.2 6.1e-34 117.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG21061.1 - 2e-08 34.8 0.0 3.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAG21061.1 - 7.2e-06 25.8 0.8 0.041 13.6 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 OAG21061.1 - 0.00079 19.6 0.0 0.0033 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAG21061.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase F-box-like PF12937.7 OAG21063.1 - 0.069 13.1 0.1 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 F-box-like His_Phos_1 PF00300.22 OAG21064.1 - 8.4e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Proteasome PF00227.26 OAG21065.1 - 5.6e-46 156.4 0.7 1e-30 106.6 0.0 2.7 2 1 1 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 OAG21065.1 - 5.3e-12 45.2 1.0 6.2e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Arm-DNA-bind_3 PF13356.6 OAG21065.1 - 0.084 13.3 0.1 3.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain DUF5633 PF18656.1 OAG21065.1 - 0.25 11.3 2.2 0.3 11.0 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Methyltransf_32 PF13679.6 OAG21066.1 - 0.0041 17.1 0.8 0.0041 17.1 0.8 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF2653 PF10850.8 OAG21066.1 - 0.098 12.9 0.4 0.24 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) MTBP_C PF14920.6 OAG21066.1 - 6 6.5 12.3 0.68 9.6 3.7 2.1 2 0 0 2 2 2 0 MDM2-binding Mitoc_mL59 PF18126.1 OAG21067.1 - 8.4e-45 152.2 0.8 1.2e-44 151.8 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Proteasome PF00227.26 OAG21068.1 - 1.6e-39 135.4 0.0 1.9e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 OAG21069.1 - 2.3e-46 157.8 0.0 7.9e-46 156.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG21069.1 - 3.1e-29 101.5 0.0 6.3e-28 97.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG21069.1 - 6.5e-05 23.0 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 OAG21069.1 - 0.00033 21.1 2.9 0.00033 21.1 2.9 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2986) CMS1 PF14617.6 OAG21069.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Velvet PF11754.8 OAG21071.1 - 1.3e-76 257.9 0.0 2.5e-46 158.6 0.0 2.3 1 1 1 2 2 2 2 Velvet factor zf-C3HC4_3 PF13920.6 OAG21072.1 - 5.1e-06 26.3 10.9 5.1e-06 26.3 10.9 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG21072.1 - 6.7 6.7 21.6 0.089 12.6 11.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mnd1 PF03962.15 OAG21073.1 - 1.2e-24 86.4 0.7 2.3e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain DUF4315 PF14193.6 OAG21073.1 - 0.033 14.2 7.1 0.15 12.1 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF4407 PF14362.6 OAG21073.1 - 0.19 11.1 4.6 0.22 10.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 OAG21073.1 - 0.37 10.8 9.2 2.2 8.3 1.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAG21073.1 - 1.6 8.8 6.6 3.4 7.8 6.6 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 OAG21073.1 - 3 6.7 9.8 2.8 6.7 1.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.32 OAG21075.1 - 8.9e-20 70.7 10.1 0.00022 22.0 0.5 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21075.1 - 4.1e-11 43.0 0.1 0.061 13.6 0.0 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAG21075.1 - 0.021 13.6 0.1 3.5 6.3 0.0 2.8 2 1 0 3 3 3 0 Nup133 N terminal like SOBP PF15279.6 OAG21076.1 - 4.6 7.8 10.8 7.1 7.1 10.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Methyltransf_16 PF10294.9 OAG21077.1 - 1.5e-45 155.0 0.0 2.2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OAG21077.1 - 6.6e-05 23.5 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG21077.1 - 0.0042 16.7 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OAG21077.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21077.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG21077.1 - 0.04 14.7 0.0 0.083 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAG21077.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Tad PF13400.6 OAG21079.1 - 0.34 11.3 3.2 1.4 9.2 2.7 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like OAD_gamma PF04277.13 OAG21079.1 - 0.6 10.7 4.0 1.2 9.8 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Misat_Tub_SegII PF10644.9 OAG21080.1 - 0.1 12.9 2.0 0.26 11.6 1.9 1.7 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain GREB1 PF15782.5 OAG21080.1 - 0.17 9.0 4.6 0.19 8.8 4.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3584 PF12128.8 OAG21080.1 - 0.99 6.8 14.6 1.2 6.6 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Asp-B-Hydro_N PF05279.11 OAG21080.1 - 1.1 9.3 8.4 1.2 9.2 8.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 OAG21080.1 - 1.3 7.7 8.2 1.5 7.5 8.2 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OAG21080.1 - 7.5 4.5 7.5 7.6 4.5 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4554 PF15091.6 OAG21080.1 - 7.6 5.3 10.6 5.9 5.7 9.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4554) RR_TM4-6 PF06459.12 OAG21080.1 - 8.8 6.1 11.1 10 5.8 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HTH_Tnp_Tc5 PF03221.16 OAG21081.1 - 1e-07 31.9 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG21081.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 OAG21081.1 - 0.0035 17.1 0.5 0.026 14.3 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_49 PF18010.1 OAG21081.1 - 0.0069 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Cry35Ab1 HTH C-terminal domain GAD-like PF08887.11 OAG21081.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 GAD-like domain HTH_28 PF13518.6 OAG21081.1 - 0.016 15.3 0.3 0.28 11.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain LCCL PF03815.19 OAG21082.1 - 2.2e-20 72.5 0.0 4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF2842 PF11003.8 OAG21082.1 - 1.4 9.2 10.1 0.7 10.2 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) SPT_ssu-like PF11779.8 OAG21082.1 - 7.1 6.3 5.8 5.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like PAP_central PF04928.17 OAG21083.1 - 0.34 9.9 1.4 0.72 8.8 1.4 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain MFAP1 PF06991.11 OAG21083.1 - 2.4 8.0 10.7 0.66 9.8 1.8 2.3 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing E1-E2_ATPase PF00122.20 OAG21084.1 - 1.2e-49 168.3 5.8 2.9e-49 167.1 5.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG21084.1 - 5.4e-23 82.4 0.2 9.8e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG21084.1 - 1.3e-05 25.5 0.7 2.8e-05 24.5 0.2 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OAG21084.1 - 0.00011 22.0 0.3 0.00048 19.9 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Methyltransf_2 PF00891.18 OAG21085.1 - 1.3e-22 80.2 0.0 3.5e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain AAA_11 PF13086.6 OAG21087.1 - 5.9e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG21087.1 - 1.9e-08 34.7 0.2 8.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG21087.1 - 2.8e-07 30.5 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG21087.1 - 4.8e-07 29.9 0.0 8.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG21087.1 - 0.00054 19.5 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 OAG21087.1 - 0.0035 17.6 4.3 0.0053 17.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 OAG21087.1 - 0.0096 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 OAG21087.1 - 0.033 14.0 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 OAG21087.1 - 0.04 14.3 0.2 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG21087.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OAG21087.1 - 0.044 14.2 1.6 0.088 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 OAG21087.1 - 0.047 13.2 0.2 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Bac_DnaA PF00308.18 OAG21087.1 - 0.065 13.1 0.4 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein Adeno_IVa2 PF02456.15 OAG21087.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_7 PF12775.7 OAG21087.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RdRP PF05183.12 OAG21088.1 - 3.9e-46 157.9 0.0 5e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_28 PF13521.6 OAG21089.1 - 8.8e-22 78.1 0.0 1e-21 77.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain E3_UbLigase_EDD PF11547.8 OAG21089.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD p450 PF00067.22 OAG21090.1 - 7.7e-33 113.9 0.0 9.5e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG21091.1 - 1.1e-24 87.0 0.0 1.5e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.22 OAG21093.1 - 4e-19 68.1 0.0 4.6e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG21093.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAG21093.1 - 0.0083 16.2 0.1 0.0094 16.0 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Rad60-SLD PF11976.8 OAG21094.1 - 1.1e-20 73.2 0.0 1.7e-17 63.0 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG21094.1 - 6e-06 25.9 0.1 9.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family adh_short PF00106.25 OAG21095.1 - 2e-37 128.5 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21095.1 - 1.7e-35 122.7 0.1 5.3e-15 55.6 0.0 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG21095.1 - 0.011 15.2 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) KR PF08659.10 OAG21095.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain AP_endonuc_2 PF01261.24 OAG21097.1 - 7.7e-36 123.5 0.0 9.8e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAHP_synth_1 PF00793.20 OAG21098.1 - 3.1e-102 341.1 0.1 3.9e-102 340.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF1013 PF06242.11 OAG21098.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Lipase_3 PF01764.25 OAG21099.1 - 4e-32 111.0 0.0 6e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 OAG21099.1 - 0.0032 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG21099.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG21099.1 - 0.0047 17.6 0.2 0.0092 16.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 OAG21099.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 Cutinase DUF676 PF05057.14 OAG21099.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OAG21099.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Claudin_2 PF13903.6 OAG21100.1 - 5.1e-05 23.1 0.8 0.019 14.7 0.1 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DNA_pol_E_B PF04042.16 OAG21101.1 - 4.8e-43 147.0 0.0 6.6e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAG21101.1 - 1.6e-37 128.5 0.0 2.5e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Gram_pos_anchor PF00746.21 OAG21102.1 - 0.47 10.4 10.5 0.16 11.9 3.7 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3328 PF11807.8 OAG21103.1 - 4.5e-25 88.7 0.0 6.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DND1_DSRM PF14709.7 OAG21104.1 - 0.022 15.0 0.7 0.054 13.8 0.7 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Nodulin_late PF07127.11 OAG21105.1 - 0.0045 17.3 3.0 0.54 10.6 0.1 2.2 2 0 0 2 2 2 2 Late nodulin protein Gamma-thionin PF00304.20 OAG21105.1 - 0.015 15.5 18.5 0.25 11.6 3.8 2.3 2 0 0 2 2 2 0 Gamma-thionin family Prokineticin PF06607.11 OAG21105.1 - 1.1 9.6 11.8 0.57 10.5 0.3 2.7 2 1 1 3 3 3 0 Prokineticin zf-NOSIP PF15906.5 OAG21105.1 - 1.6 8.9 6.0 2.4 8.4 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Toxin_2 PF00451.19 OAG21105.1 - 5.4 7.4 22.9 3.1 8.2 7.8 2.4 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 FANCI_HD1 PF14679.6 OAG21106.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 FANCI helical domain 1 ABC_membrane PF00664.23 OAG21107.1 - 2.7e-56 191.2 38.0 1e-36 127.1 18.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAG21107.1 - 3.5e-48 163.6 2.0 4e-27 95.4 0.1 3.1 3 0 0 3 3 2 2 ABC transporter Zeta_toxin PF06414.12 OAG21107.1 - 1.2e-06 27.9 0.0 0.00033 20.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 OAG21107.1 - 4.8e-06 26.6 2.5 0.039 14.0 0.1 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG21107.1 - 2.9e-05 23.7 0.9 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG21107.1 - 4.7e-05 23.4 0.9 0.46 10.2 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG21107.1 - 5.5e-05 23.6 0.0 0.079 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG21107.1 - 0.00023 21.1 2.2 0.058 13.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OAG21107.1 - 0.00068 20.2 7.3 0.7 10.4 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OAG21107.1 - 0.0017 18.1 1.7 0.74 9.5 0.1 2.7 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 OAG21107.1 - 0.0018 17.8 12.5 0.39 10.1 0.8 4.1 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OAG21107.1 - 0.0079 16.5 0.8 0.15 12.3 0.0 3.2 4 0 0 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.9 OAG21107.1 - 0.014 14.3 0.2 0.99 8.2 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 OAG21107.1 - 0.02 13.7 0.4 8.2 5.1 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 OAG21107.1 - 0.022 14.5 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 OAG21107.1 - 0.035 14.0 0.4 8.8 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 OAG21107.1 - 0.054 13.0 0.2 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 OAG21107.1 - 0.06 13.0 1.4 6.8 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OAG21107.1 - 0.085 13.1 1.5 19 5.5 0.2 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG21107.1 - 0.19 11.7 11.4 0.58 10.2 0.7 3.3 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 OAG21107.1 - 0.58 10.4 3.4 17 5.6 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 OAG21107.1 - 1.4 7.9 8.1 1.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 OAG21107.1 - 3.6 7.6 13.5 0.13 12.3 0.3 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain Aminotran_3 PF00202.21 OAG21108.1 - 3.5e-112 375.0 0.0 5.8e-111 371.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAG21108.1 - 0.0007 19.0 0.0 0.004 16.5 0.0 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAG21108.1 - 0.0075 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0556 PF10572.9 OAG21108.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 HAD PF12710.7 OAG21109.1 - 4.3e-05 24.0 0.2 0.00034 21.1 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_1 PF00515.28 OAG21109.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG21109.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HAD_2 PF13419.6 OAG21109.1 - 0.11 12.6 0.0 0.87 9.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG21109.1 - 0.14 12.4 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase C2 PF00168.30 OAG21110.1 - 8.7e-25 87.0 0.1 9.1e-12 45.2 0.0 2.8 3 0 0 3 3 3 2 C2 domain WD40 PF00400.32 OAG21111.1 - 3.4e-60 198.6 30.9 1.5e-09 38.3 0.1 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21111.1 - 3.1e-24 85.1 1.6 2e-05 24.8 0.0 6.6 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG21111.1 - 5.4e-06 25.6 0.1 0.052 12.5 0.0 4.0 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG21111.1 - 0.00021 20.1 5.7 0.76 8.3 0.1 5.1 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 OAG21111.1 - 0.00024 20.5 0.1 3.8 6.8 0.0 4.0 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal NLE PF08154.12 OAG21111.1 - 0.00043 20.7 0.0 0.00095 19.6 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain TFIIIC_delta PF12657.7 OAG21111.1 - 0.02 14.9 0.5 5.8 6.8 0.0 3.5 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.9 OAG21111.1 - 0.047 13.4 0.8 11 5.8 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 OAG21111.1 - 0.075 13.0 0.1 77 3.4 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PsaD PF02531.16 OAG21111.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 1 1 0 1 1 1 0 PsaD Cytotoxic PF09000.10 OAG21111.1 - 0.29 11.5 1.6 65 3.9 0.3 3.6 2 1 1 3 3 3 0 Cytotoxic MutS_V PF00488.21 OAG21112.1 - 9.4e-63 211.7 0.9 1.6e-62 210.9 0.3 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAG21112.1 - 1.6e-33 116.5 1.6 1.6e-33 116.5 1.6 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAG21112.1 - 3e-11 43.7 0.1 7.9e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG21112.1 - 2.2e-07 31.1 0.2 6.2e-07 29.7 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 OAG21112.1 - 0.0047 16.6 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Fungal_trans_2 PF11951.8 OAG21113.1 - 2.8e-62 210.7 0.0 4e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21113.1 - 1.3e-08 34.9 9.0 2.2e-08 34.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MLP1_2 PF07926.12 OAG21114.1 - 0.22 11.6 7.5 0.3 11.1 7.5 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF5446 PF17522.2 OAG21114.1 - 0.81 9.9 2.9 1.4 9.2 2.8 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5446) RAMP4 PF06624.12 OAG21115.1 - 2.6e-14 53.0 0.5 3e-14 52.8 0.5 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.20 OAG21116.1 - 1e-80 271.8 0.0 2.1e-80 270.8 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 OAG21116.1 - 2.3e-05 24.8 2.9 1.8 9.2 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 OAG21116.1 - 0.00052 20.1 0.0 0.022 14.8 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG21116.1 - 0.00068 20.0 2.2 0.15 12.5 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OAG21116.1 - 0.0061 16.7 0.1 15 6.2 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat NUDE_C PF04880.13 OAG21116.1 - 0.41 11.1 9.2 1.1 9.8 9.2 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CCSAP PF15748.5 OAG21116.1 - 3.3 7.8 9.8 6.4 6.9 9.8 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated F-box-like PF12937.7 OAG21119.1 - 1.1e-08 34.9 1.5 4.4e-06 26.5 0.0 3.1 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OAG21119.1 - 1e-05 25.2 0.6 0.00032 20.5 0.0 3.3 2 0 0 2 2 2 1 F-box domain RSN1_7TM PF02714.15 OAG21120.1 - 8.5e-72 241.7 21.3 8.5e-72 241.7 21.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG21120.1 - 8.1e-40 136.9 0.0 1.2e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG21120.1 - 9.1e-40 136.0 1.2 9.1e-40 136.0 1.2 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3671 PF12420.8 OAG21120.1 - 0.0043 17.1 0.5 0.0043 17.1 0.5 3.5 4 0 0 4 4 4 1 Protein of unknown function YMF19 PF02326.15 OAG21120.1 - 1.4 9.7 11.2 0.97 10.3 0.5 3.6 3 0 0 3 3 3 0 Plant ATP synthase F0 Pkinase PF00069.25 OAG21121.1 - 5.2e-07 29.3 0.0 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2333 PF10095.9 OAG21121.1 - 0.09 11.8 0.1 0.2 10.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) TPMT PF05724.11 OAG21122.1 - 6.1e-28 98.0 0.1 1e-27 97.2 0.1 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAG21122.1 - 3.8e-07 30.7 0.0 7.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG21122.1 - 2.4e-06 28.2 0.0 4.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG21122.1 - 8.2e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG21122.1 - 1.5e-05 25.5 0.0 2.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21122.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OAG21122.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein DUF3810 PF12725.7 OAG21123.1 - 0.0091 15.4 1.1 0.03 13.7 1.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) Peptidase_S46 PF10459.9 OAG21123.1 - 0.055 12.1 0.8 0.072 11.7 0.8 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_M10 PF00413.24 OAG21123.1 - 0.12 12.2 0.5 0.41 10.5 0.3 2.0 1 1 0 1 1 1 0 Matrixin ORC2 PF04084.14 OAG21124.1 - 1.4e-117 392.3 0.0 1.7e-117 392.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 OAG21124.1 - 3.4 6.8 14.1 9.4 5.4 14.1 1.8 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATG101 PF07855.12 OAG21125.1 - 2.6e-53 180.2 1.1 3e-53 179.9 1.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 OAG21125.1 - 0.04 13.9 0.5 0.1 12.6 0.3 1.7 1 1 1 2 2 2 0 Mo-co oxidoreductase dimerisation domain T5orf172 PF10544.9 OAG21126.1 - 8.4e-28 96.9 0.4 2.1e-27 95.7 0.4 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG21126.1 - 3.3e-26 91.7 0.3 7e-26 90.7 0.3 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 zf-primase PF09329.11 OAG21126.1 - 0.021 14.7 0.2 0.052 13.4 0.2 1.6 1 0 0 1 1 1 0 Primase zinc finger MIP PF00230.20 OAG21127.1 - 1.1e-48 166.0 13.9 1.3e-48 165.7 13.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Radical_SAM_C PF16199.5 OAG21128.1 - 1.4e-32 111.5 0.1 4.9e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAG21128.1 - 1.7e-17 64.3 0.1 5.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAG21128.1 - 5e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG21128.1 - 4.6e-06 26.6 0.1 4.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG21128.1 - 0.084 13.3 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1282 PF06930.12 OAG21129.1 - 0.008 16.0 0.2 0.0094 15.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF2892 PF11127.8 OAG21129.1 - 0.012 15.6 2.1 0.03 14.4 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) SNF2_N PF00176.23 OAG21130.1 - 1.4e-52 178.6 0.2 2.6e-44 151.4 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG21130.1 - 6.9e-17 61.8 0.0 8.2e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OAG21130.1 - 3.8e-05 23.5 11.3 3.8e-05 23.5 11.3 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 OAG21130.1 - 0.00013 21.0 0.0 0.00029 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 OAG21130.1 - 0.0034 17.2 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 OAG21130.1 - 0.0073 16.1 10.5 0.0073 16.1 10.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 OAG21130.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-rbx1 PF12678.7 OAG21130.1 - 0.43 10.9 8.4 1.3 9.4 8.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 OAG21130.1 - 1.2 9.2 14.0 2.4 8.2 1.0 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.6 OAG21130.1 - 1.9 8.6 15.4 0.07 13.2 8.8 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAG21130.1 - 7.5 7.0 24.5 0.021 15.2 12.2 2.5 2 0 0 2 2 2 0 Ring finger domain HPP PF04982.13 OAG21131.1 - 4.2e-38 130.3 7.7 4.6e-38 130.1 5.1 1.9 2 0 0 2 2 2 1 HPP family ABC_tran PF00005.27 OAG21132.1 - 2e-47 161.1 0.1 3.6e-23 82.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG21132.1 - 1.1e-21 76.6 2.6 1.1e-21 76.6 2.6 2.4 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 OAG21132.1 - 2.6e-16 60.3 6.2 0.00096 19.0 0.0 4.3 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG21132.1 - 3.8e-09 36.3 1.1 0.52 9.7 0.0 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG21132.1 - 3.6e-08 33.0 0.2 0.0023 17.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAG21132.1 - 1.4e-07 31.5 2.8 0.014 15.1 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG21132.1 - 3e-07 30.5 0.3 0.00027 20.9 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAG21132.1 - 3.8e-07 30.6 0.0 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG21132.1 - 4.2e-06 27.4 13.9 0.017 15.6 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAG21132.1 - 1.5e-05 25.6 0.3 0.22 12.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 OAG21132.1 - 3.2e-05 24.2 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG21132.1 - 7.4e-05 22.8 0.0 0.016 15.3 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG21132.1 - 9.1e-05 22.8 0.0 0.44 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG21132.1 - 0.00012 22.5 1.0 1.3 9.4 0.0 3.5 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 OAG21132.1 - 0.00021 21.2 0.1 0.24 11.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 OAG21132.1 - 0.00023 20.8 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG21132.1 - 0.0003 21.2 0.0 0.58 10.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OAG21132.1 - 0.0005 20.3 0.1 1.7 8.8 0.1 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OAG21132.1 - 0.0006 19.1 0.5 2 7.6 0.2 3.3 2 1 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 OAG21132.1 - 0.001 18.8 0.4 1.9 8.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OAG21132.1 - 0.0035 17.4 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAG21132.1 - 0.0048 16.9 0.1 7 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAG21132.1 - 0.0076 16.0 1.0 0.31 10.8 0.0 3.1 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 OAG21132.1 - 0.0097 15.5 0.3 3.4 7.2 0.0 2.8 3 0 0 3 3 3 1 Ras family AAA_7 PF12775.7 OAG21132.1 - 0.015 14.8 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAG21132.1 - 0.015 15.4 2.1 3 8.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain FeoB_N PF02421.18 OAG21132.1 - 0.018 14.6 0.2 1.6 8.3 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Phage_tail_2 PF06199.11 OAG21132.1 - 0.024 14.8 0.0 0.095 12.8 0.0 2.0 2 0 0 2 2 1 0 Phage tail tube protein AAA_25 PF13481.6 OAG21132.1 - 0.029 13.9 0.9 1.6 8.3 0.0 3.6 4 1 1 5 5 4 0 AAA domain ATPase_2 PF01637.18 OAG21132.1 - 0.031 14.2 0.1 5.4 6.9 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAG21132.1 - 0.046 13.4 0.1 8.9 6.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG21132.1 - 0.096 12.7 0.1 19 5.2 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OAG21132.1 - 0.1 13.1 0.6 20 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAG21132.1 - 0.11 12.4 0.4 8.4 6.3 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.6 OAG21132.1 - 0.37 9.4 10.0 5.6 5.5 0.2 4.6 4 1 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 OAG21132.1 - 0.42 10.7 5.2 1.1 9.3 0.0 3.5 4 1 1 5 5 3 0 Dynamin family cobW PF02492.19 OAG21132.1 - 0.63 9.6 2.7 22 4.6 0.3 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Ureide_permease PF07168.11 OAG21132.1 - 3.1 6.5 5.2 2.2 7.0 1.6 2.1 2 0 0 2 2 2 0 Ureide permease CLTH PF10607.9 OAG21133.1 - 6.1e-28 97.6 0.0 1.9e-27 96.0 0.0 1.8 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Adaptin_binding PF10199.9 OAG21133.1 - 0.032 14.8 0.4 0.057 14.0 0.4 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BAR PF03114.18 OAG21133.1 - 0.08 12.6 1.2 0.18 11.4 1.2 1.5 1 0 0 1 1 1 0 BAR domain DUF745 PF05335.13 OAG21133.1 - 0.088 12.5 3.3 0.15 11.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2431 PF10354.9 OAG21134.1 - 2.2e-61 207.0 0.0 3.4e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Capsid-VNN PF11729.8 OAG21134.1 - 7.9 5.4 8.1 1 8.3 3.8 1.6 2 0 0 2 2 2 0 nodavirus capsid protein CoA_binding PF02629.19 OAG21135.1 - 1.2e-27 96.5 1.4 1.2e-27 96.5 1.4 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAG21135.1 - 3.3e-24 85.4 0.3 7.7e-24 84.3 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG21135.1 - 7e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAG21135.1 - 2.9e-05 24.5 0.0 0.00012 22.5 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 OAG21135.1 - 0.03 15.2 0.2 0.1 13.4 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1929 PF09118.11 OAG21136.1 - 0.086 13.1 0.1 0.091 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) Ribosomal_L5_C PF00673.21 OAG21137.1 - 1e-26 92.9 0.0 3.1e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG21137.1 - 3.2e-10 40.2 0.0 6.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 OAG21138.1 - 7.6e-18 65.2 0.0 1.4e-07 31.5 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pho88 PF10032.9 OAG21139.1 - 7.4e-82 273.0 0.0 8.4e-82 272.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF1240 PF06836.12 OAG21139.1 - 0.079 13.5 0.6 0.15 12.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) DUF4512 PF14975.6 OAG21139.1 - 0.1 13.4 0.2 2.4 9.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Fungal_trans PF04082.18 OAG21140.1 - 9.4e-15 54.3 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21140.1 - 2.2e-07 30.9 7.7 3.7e-07 30.1 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 OAG21143.1 - 7.8e-33 113.5 0.0 2e-30 105.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG21143.1 - 1.4e-08 33.9 0.1 7.5e-08 31.6 0.1 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG21143.1 - 6.4e-05 22.1 0.1 0.0054 15.8 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 OAG21143.1 - 0.0021 17.4 1.0 0.016 14.5 0.2 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG21143.1 - 0.068 13.8 3.0 0.055 14.1 0.8 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family PBD PF00786.28 OAG21144.1 - 0.025 14.9 0.0 0.069 13.5 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain NDUF_B12 PF08122.12 OAG21146.1 - 3.5e-22 78.2 0.5 5e-22 77.7 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 OAG21147.1 - 2e-23 83.1 0.0 5e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 CAF1 family ribonuclease Brix PF04427.18 OAG21148.1 - 1.4e-24 87.3 0.1 2.5e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 OAG21148.1 - 0.4 10.0 26.9 0.57 9.5 26.9 1.1 1 0 0 1 1 1 0 BUD22 Pes-10 PF07149.11 OAG21148.1 - 5.8 5.9 12.5 8.4 5.3 12.5 1.1 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 OAG21148.1 - 6 4.9 24.8 8.4 4.5 24.8 1.1 1 0 0 1 1 1 0 Nop14-like family HGTP_anticodon PF03129.20 OAG21149.1 - 4.1e-22 78.1 0.0 4.1e-22 78.1 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAG21149.1 - 1.5e-07 31.6 0.0 3.7e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Methyltransf_23 PF13489.6 OAG21150.1 - 4.1e-13 49.5 0.0 7.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21150.1 - 2.2e-09 37.9 0.0 1.2e-06 29.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OAG21150.1 - 3.5e-08 33.4 0.0 3.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG21150.1 - 3.7e-06 27.5 0.0 0.015 15.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG21150.1 - 4.2e-05 24.2 0.0 0.0082 16.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG21150.1 - 7.1e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG21150.1 - 0.00028 20.4 0.0 0.00082 18.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 OAG21150.1 - 0.0052 16.9 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAG21150.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 OAG21150.1 - 0.073 12.6 0.0 1.5 8.3 0.0 2.2 1 1 1 2 2 2 0 Histone methylation protein DOT1 PCMT PF01135.19 OAG21150.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short_C2 PF13561.6 OAG21151.1 - 8.1e-36 123.7 0.0 4.8e-35 121.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG21151.1 - 2.7e-25 89.0 0.0 5.2e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG21151.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain PAP2 PF01569.21 OAG21152.1 - 2.6e-26 92.0 1.6 2.6e-26 92.0 1.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily Cadherin_C_2 PF16492.5 OAG21153.1 - 0.096 13.4 0.0 0.24 12.2 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RMMBL PF07521.12 OAG21153.1 - 0.099 12.6 0.0 0.8 9.7 0.1 2.1 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain SF1-HH PF16275.5 OAG21153.1 - 0.11 12.8 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain NmrA PF05368.13 OAG21155.1 - 3.9e-20 72.4 0.0 5.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG21155.1 - 2.7e-15 56.7 0.0 3.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG21155.1 - 3.6e-05 24.0 0.0 5.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG21155.1 - 0.00014 21.0 0.2 0.00024 20.2 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG21155.1 - 0.00027 21.3 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG21155.1 - 0.0005 20.1 0.1 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG21155.1 - 0.0026 18.3 0.1 0.0046 17.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 OAG21155.1 - 0.0041 16.3 0.3 0.0066 15.6 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG21155.1 - 0.0055 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 OAG21155.1 - 0.008 16.3 0.4 0.013 15.6 0.4 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 OAG21155.1 - 0.029 13.9 0.1 0.06 12.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAG21156.1 - 3e-05 24.1 9.9 5.9e-05 23.1 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2423 PF10338.9 OAG21157.1 - 1.8e-20 72.8 1.4 1.8e-20 72.8 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 OAG21158.1 - 1.3e-35 122.9 0.1 2.4e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAG21158.1 - 6.5e-20 70.6 3.9 1.1e-19 69.9 3.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAG21158.1 - 1.4e-07 31.2 1.5 3e-07 30.1 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OAG21158.1 - 7.1e-07 28.8 0.2 1.8e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 OAG21158.1 - 0.0065 16.3 1.4 0.013 15.3 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF3552 PF12072.8 OAG21159.1 - 0.0021 17.5 15.9 0.0021 17.5 15.9 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3552) PARM PF17061.5 OAG21159.1 - 2.1 8.4 8.5 0.077 13.1 2.0 1.8 2 0 0 2 2 2 0 PARM FAD_binding_4 PF01565.23 OAG21160.1 - 9.7e-21 74.0 4.8 3.7e-20 72.1 2.7 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG21160.1 - 1.5e-10 41.0 0.1 3.5e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF5527 PF17665.1 OAG21161.1 - 0.083 12.4 0.8 0.16 11.5 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) GST_N_2 PF13409.6 OAG21163.1 - 4.8e-17 62.0 0.0 8.9e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG21163.1 - 1.8e-15 56.7 0.0 4.2e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG21163.1 - 6.6e-07 29.5 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG21163.1 - 0.00047 20.3 0.1 0.00091 19.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG21163.1 - 0.0013 19.1 0.0 0.017 15.5 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Chlorophyllase2 PF12740.7 OAG21164.1 - 2.7e-08 33.1 0.0 3.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAG21164.1 - 7.7e-05 21.4 0.1 0.013 14.1 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 OAG21164.1 - 0.00027 20.1 0.0 0.00037 19.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 OAG21164.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG21164.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 OAG21164.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MARVEL PF01284.23 OAG21165.1 - 2.4e-08 34.1 11.4 3.4e-08 33.6 11.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain NCE101 PF11654.8 OAG21165.1 - 0.011 15.5 0.2 0.025 14.3 0.2 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 F-box PF00646.33 OAG21166.1 - 9.4e-05 22.2 0.1 0.00022 21.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG21166.1 - 0.0052 16.6 0.3 0.029 14.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like Ysc84 PF04366.12 OAG21167.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Las17-binding protein actin regulator Xan_ur_permease PF00860.20 OAG21168.1 - 4.6e-28 98.0 32.0 4.1e-26 91.6 31.5 3.0 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.20 OAG21168.1 - 7e-05 21.7 14.3 0.00055 18.8 2.6 2.7 2 1 1 3 3 3 2 Sulfate permease family CRM1_repeat_3 PF18787.1 OAG21168.1 - 1.8 8.8 3.3 0.73 10.0 0.3 2.0 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 Methyltransf_11 PF08241.12 OAG21169.1 - 8.9e-09 35.9 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21169.1 - 4.7e-05 24.0 0.0 9.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG21169.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG21169.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AA_permease PF00324.21 OAG21171.1 - 6e-139 463.7 45.5 7.4e-139 463.4 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG21171.1 - 3e-36 125.2 51.8 3.8e-36 124.8 51.8 1.1 1 0 0 1 1 1 1 Amino acid permease Pam17 PF08566.10 OAG21173.1 - 7.4e-58 195.0 0.0 1e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 NMO PF03060.15 OAG21174.1 - 8.6e-29 101.0 3.7 1.3e-22 80.6 0.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 OAG21174.1 - 6.6e-10 38.5 0.1 2.3e-08 33.4 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG21174.1 - 2.8e-05 23.5 0.1 4.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 OAG21174.1 - 0.0027 16.8 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAG21174.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein p450 PF00067.22 OAG21175.1 - 2.4e-73 247.5 0.0 2.9e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.17 OAG21175.1 - 0.028 14.6 0.0 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 K-box region Cyt_c_ox_IV PF12270.8 OAG21175.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Pkinase PF00069.25 OAG21176.1 - 1.1e-73 247.8 0.0 1.6e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21176.1 - 5.1e-36 124.3 0.0 6.9e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG21176.1 - 9.6e-17 61.1 0.2 7.4e-16 58.3 0.1 2.3 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 OAG21176.1 - 8.4e-10 38.4 0.0 8.8e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAG21176.1 - 3e-08 32.9 0.0 1.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAG21176.1 - 6.5e-07 29.6 0.1 5.9e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAG21176.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG21176.1 - 0.037 14.0 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAG21176.1 - 0.044 12.8 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 OAG21176.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OAG21176.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF2961 PF11175.8 OAG21176.1 - 0.13 11.9 0.1 14 5.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2961) Autophagy_act_C PF03987.15 OAG21177.1 - 3.6e-14 53.1 1.3 6.9e-14 52.2 0.9 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain DAP3 PF10236.9 OAG21178.1 - 5.8e-101 337.8 0.0 7.2e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAG21178.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RRS1 PF04939.12 OAG21179.1 - 7e-58 195.1 4.7 8.3e-58 194.8 4.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Dppa2_A PF14049.6 OAG21179.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.7 3 0 0 3 3 3 0 Dppa2/4 conserved region in higher vertebrates MFS_1 PF07690.16 OAG21180.1 - 1.7e-31 109.5 29.4 2.6e-31 108.8 29.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAG21181.1 - 2.3e-39 135.3 45.6 3.9e-39 134.6 45.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG21181.1 - 4.4e-08 32.0 20.7 1.2e-07 30.5 20.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adeno_PV PF03910.13 OAG21181.1 - 0.28 9.9 0.1 0.42 9.3 0.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Fst_toxin PF13955.6 OAG21181.1 - 1.3 9.0 5.5 7.2 6.7 5.5 2.3 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system SWIRM-assoc_1 PF16495.5 OAG21182.1 - 0.13 12.2 0.5 0.5 10.4 0.5 2.0 1 0 0 1 1 1 0 SWIRM-associated region 1 bZIP_Maf PF03131.17 OAG21183.1 - 0.038 14.5 4.2 0.038 14.5 4.2 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG21183.1 - 0.34 11.0 11.6 0.74 9.9 11.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CDC45 PF02724.14 OAG21183.1 - 7.8 4.6 8.3 9.1 4.4 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein R3H-assoc PF13902.6 OAG21186.1 - 0.0039 17.6 0.1 0.0058 17.0 0.1 1.3 1 0 0 1 1 1 1 R3H-associated N-terminal domain DUF5550 PF17704.1 OAG21186.1 - 0.019 15.1 0.1 0.035 14.2 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5550) zf-H2C2_2 PF13465.6 OAG21187.1 - 7.8e-14 51.4 20.3 7.4e-07 29.3 3.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG21187.1 - 3.3e-08 33.5 30.7 0.0033 17.8 3.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG21187.1 - 0.00019 21.3 19.4 0.071 13.1 0.9 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger FlxA PF14282.6 OAG21187.1 - 0.0009 19.2 1.8 0.0009 19.2 1.8 2.4 2 0 0 2 2 2 1 FlxA-like protein zf-Di19 PF05605.12 OAG21187.1 - 0.0038 17.5 6.1 0.0038 17.5 6.1 2.1 2 0 0 2 2 1 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 OAG21187.1 - 0.01 15.6 7.9 0.016 15.0 1.4 2.8 1 1 1 2 2 2 0 GAGA factor Pacs-1 PF10254.9 OAG21187.1 - 0.01 14.8 0.4 0.022 13.7 0.4 1.5 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein zf-C2H2_4 PF13894.6 OAG21187.1 - 0.022 15.6 16.1 0.029 15.2 6.4 5.0 5 0 0 5 5 3 0 C2H2-type zinc finger FAM184 PF15665.5 OAG21187.1 - 0.023 14.5 2.9 0.04 13.7 2.9 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FAM76 PF16046.5 OAG21187.1 - 0.028 13.8 0.6 0.028 13.8 0.6 3.3 4 1 0 4 4 4 0 FAM76 protein FYVE PF01363.21 OAG21187.1 - 0.028 14.5 4.4 0.14 12.3 0.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 OAG21187.1 - 0.044 14.1 7.6 3.8 7.9 2.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OAG21187.1 - 0.062 13.2 0.6 0.062 13.2 0.6 2.7 3 0 0 3 3 2 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 OAG21187.1 - 0.071 13.0 9.9 0.34 10.8 1.3 3.4 2 1 1 3 3 3 0 Rad50 zinc hook motif SurA_N_2 PF13623.6 OAG21187.1 - 0.077 12.9 2.3 0.15 11.9 2.3 1.4 1 0 0 1 1 1 0 SurA N-terminal domain zf-C2H2_9 PF16293.5 OAG21187.1 - 0.15 12.0 5.0 5 7.0 0.2 2.9 2 1 1 3 3 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 OAG21187.1 - 0.7 10.1 7.6 0.97 9.6 2.3 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf-CHCC PF10276.9 OAG21187.1 - 0.75 9.9 8.4 1.2 9.2 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 OAG21187.1 - 0.8 9.8 8.2 12 6.0 8.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 OAG21187.1 - 4.2 7.7 5.8 26 5.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon C1_4 PF07975.12 OAG21187.1 - 4.9 7.5 7.5 1.1e+02 3.1 7.6 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain Pkinase PF00069.25 OAG21189.1 - 1e-66 225.0 0.0 1.4e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21189.1 - 1.3e-49 168.8 0.0 2.2e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG21189.1 - 0.003 16.4 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PI3_PI4_kinase PF00454.27 OAG21190.1 - 4e-38 131.7 0.0 1.8e-28 100.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAG21190.1 - 1.6e-24 86.3 0.4 3.4e-24 85.3 0.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CK2S PF15011.6 OAG21190.1 - 0.022 14.7 1.9 0.066 13.1 0.5 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate AKAP95 PF04988.12 OAG21190.1 - 0.13 12.5 0.1 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) MFS_1 PF07690.16 OAG21191.1 - 3.8e-45 154.3 57.6 3.8e-45 154.3 57.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG21191.1 - 3.8e-19 68.6 29.1 6.3e-19 67.8 29.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG21191.1 - 4.7e-09 35.6 14.4 4.7e-09 35.6 14.4 3.7 2 1 0 3 3 3 1 Sugar (and other) transporter GATA PF00320.27 OAG21192.1 - 0.024 14.2 2.2 0.59 9.8 0.5 2.7 2 0 0 2 2 2 0 GATA zinc finger DUF2752 PF10825.8 OAG21192.1 - 0.38 10.8 3.3 0.45 10.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) p450 PF00067.22 OAG21194.1 - 4.5e-56 190.5 0.0 5.7e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.15 OAG21195.1 - 1.6e-18 66.5 0.5 1.9e-18 66.3 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG21195.1 - 9.3e-08 32.7 0.1 1.1e-07 32.5 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OAG21195.1 - 0.022 15.4 0.5 0.34 11.5 0.1 2.0 1 1 1 2 2 2 0 Complex1_LYR-like HSP20 PF00011.21 OAG21196.1 - 3e-23 81.9 2.6 3.6e-15 56.0 0.2 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG21196.1 - 1.1e-07 31.3 0.0 1.2e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HisG PF01634.18 OAG21197.1 - 9.1e-56 188.2 0.1 1.3e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAG21197.1 - 2.9e-26 91.4 0.2 6.6e-26 90.3 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 OAG21197.1 - 0.023 14.6 0.1 0.074 13.0 0.1 1.8 1 1 0 1 1 1 0 NMT1/THI5 like P22_Cro PF14549.6 OAG21197.1 - 0.16 11.8 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro eIF3_subunit PF08597.10 OAG21198.1 - 4.3e-70 236.4 30.5 4.9e-70 236.2 30.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GHMP_kinases_N PF00288.26 OAG21199.1 - 4e-15 55.8 0.0 1.1e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG21199.1 - 3.8e-08 33.6 0.0 9.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAG21199.1 - 0.0063 16.0 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature G-patch PF01585.23 OAG21200.1 - 2.5e-05 24.1 0.0 0.00017 21.4 0.0 2.4 1 1 0 1 1 1 1 G-patch domain CDKN3 PF05706.12 OAG21200.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF936 PF06075.12 OAG21200.1 - 0.2 10.5 33.1 0.29 10.0 33.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Bap31_Bap29_C PF18035.1 OAG21201.1 - 0.0024 17.9 1.4 0.007 16.3 1.4 1.8 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Gam PF06064.11 OAG21201.1 - 0.0033 17.6 0.9 0.0053 17.0 0.4 1.7 1 1 0 1 1 1 1 Host-nuclease inhibitor protein Gam YjcZ PF13990.6 OAG21201.1 - 0.0096 15.3 2.4 0.013 14.9 2.4 1.1 1 0 0 1 1 1 1 YjcZ-like protein FCH PF00611.23 OAG21201.1 - 0.01 16.1 4.9 0.027 14.7 2.6 2.2 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1759 PF03564.15 OAG21201.1 - 0.23 11.4 3.4 0.32 10.9 0.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) DUF1664 PF07889.12 OAG21201.1 - 0.3 11.1 5.2 0.13 12.3 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PH_4 PF15404.6 OAG21201.1 - 0.83 9.4 4.9 0.18 11.6 0.9 1.7 1 1 1 2 2 2 0 Pleckstrin homology domain HIP1_clath_bdg PF16515.5 OAG21201.1 - 3.1 8.5 11.2 0.62 10.7 2.7 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec2p PF06428.11 OAG21201.1 - 5.8 7.0 13.4 2.8 8.0 3.9 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 OAG21201.1 - 9.3 5.5 13.1 1.1 8.6 2.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Arrestin_N PF00339.29 OAG21202.1 - 3.3e-16 59.6 0.7 1.5e-15 57.5 0.0 2.6 4 1 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAG21202.1 - 2.3e-11 44.3 0.0 1.3e-06 28.9 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DEAD PF00270.29 OAG21203.1 - 6.1e-38 130.3 0.0 9.2e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG21203.1 - 1.9e-22 79.7 0.0 2e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG21203.1 - 5.1e-06 26.6 0.0 8.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG21203.1 - 0.046 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PHF12_MRG_bd PF16737.5 OAG21203.1 - 0.091 12.5 0.2 0.84 9.4 0.0 2.4 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain Forkhead PF00250.18 OAG21205.1 - 9.9e-34 115.5 0.5 1.9e-33 114.6 0.5 1.5 1 0 0 1 1 1 1 Forkhead domain ArgJ PF01960.18 OAG21206.1 - 3.8e-150 499.8 1.6 4.3e-150 499.6 1.6 1.0 1 0 0 1 1 1 1 ArgJ family DUF1275 PF06912.11 OAG21207.1 - 0.0018 18.3 1.2 0.0021 18.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) G10 PF01125.17 OAG21209.1 - 2.8e-66 221.8 7.2 3.1e-66 221.6 7.2 1.0 1 0 0 1 1 1 1 G10 protein YqbF PF14553.6 OAG21209.1 - 0.051 13.4 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain LisH PF08513.11 OAG21209.1 - 0.26 11.3 0.5 0.26 11.3 0.5 1.9 2 0 0 2 2 2 0 LisH Complex1_LYR_2 PF13233.6 OAG21210.1 - 1.5e-06 28.8 1.3 3e-06 27.9 1.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAG21210.1 - 0.0003 20.8 0.2 0.00062 19.8 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) RRM_Rrp7 PF17799.1 OAG21210.1 - 0.038 13.8 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RNA_pol_L_2 PF13656.6 OAG21211.1 - 8.7e-32 108.7 0.0 1.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG21211.1 - 1.7e-13 49.8 0.0 2.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IGPD PF00475.18 OAG21212.1 - 1.3e-58 197.4 0.5 1.9e-58 196.9 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase RPE65 PF03055.15 OAG21214.1 - 1.4e-79 268.5 0.0 1.7e-79 268.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4267 PF14087.6 OAG21215.1 - 1.7e-15 57.1 3.4 2.1e-15 56.8 3.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) Adap_comp_sub PF00928.21 OAG21216.1 - 2.3e-85 286.1 0.0 2.9e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG21216.1 - 1.5e-05 24.9 0.2 2.8e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OAG21216.1 - 0.0064 16.0 0.2 0.01 15.3 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RIBIOP_C PF04950.12 OAG21216.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NAD_binding_4 PF07993.12 OAG21218.1 - 6.9e-43 146.7 0.0 1.4e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG21218.1 - 8.1e-30 103.8 0.1 1.3e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG21218.1 - 5.3e-09 36.3 0.1 1.7e-08 34.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAG21218.1 - 6.6e-09 35.6 0.0 1.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_33 PF13671.6 OAG21218.1 - 8.1e-08 32.5 0.0 3.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG21218.1 - 1.5e-07 32.0 0.0 3.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 OAG21218.1 - 4.3e-07 30.2 0.1 1.4e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 Shikimate kinase KR PF08659.10 OAG21218.1 - 0.0012 18.7 0.4 0.23 11.4 0.0 3.3 3 0 0 3 3 3 1 KR domain dNK PF01712.19 OAG21218.1 - 0.0036 17.2 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Deoxynucleoside kinase CPT PF07931.12 OAG21218.1 - 0.0038 17.1 3.1 0.094 12.5 0.9 3.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 OAG21218.1 - 0.0079 16.0 0.0 0.037 13.8 0.0 1.9 1 1 0 2 2 2 1 Cytidylate kinase 3Beta_HSD PF01073.19 OAG21218.1 - 0.014 14.4 0.0 0.044 12.8 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_29 PF13555.6 OAG21218.1 - 0.025 14.3 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG21218.1 - 0.031 13.9 0.4 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG21218.1 - 0.039 14.4 0.2 0.15 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 OAG21218.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_22 PF13401.6 OAG21218.1 - 0.15 12.4 0.0 0.57 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OAG21219.1 - 6.5e-39 133.9 26.0 6.5e-39 133.9 26.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 OAG21219.1 - 0.0011 19.3 0.6 0.0041 17.4 0.6 2.0 1 0 0 1 1 1 1 Stage V sporulation protein AB TraL PF07178.11 OAG21219.1 - 1.4 9.4 8.3 0.14 12.7 1.7 2.9 3 0 0 3 3 3 0 TraL protein Fungal_trans PF04082.18 OAG21220.1 - 2e-31 109.0 0.0 3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21220.1 - 4.9e-08 33.0 9.3 1.1e-07 31.8 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAG21221.1 - 8.6e-45 153.2 0.0 1e-43 149.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TrmB PF01978.19 OAG21221.1 - 0.17 11.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phage_X PF05155.15 OAG21221.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage X family p450 PF00067.22 OAG21222.1 - 6.7e-49 166.9 0.0 8.6e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.6 OAG21223.1 - 1.6e-05 25.2 0.2 7.2e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 AIG2-like family A_deaminase PF00962.22 OAG21224.1 - 2.6e-81 273.5 0.0 3.1e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase RRM_1 PF00076.22 OAG21225.1 - 5.5e-10 38.9 0.1 1.6e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG21225.1 - 0.00021 20.8 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 OAG21225.1 - 0.00031 20.5 0.3 0.00059 19.6 0.3 1.5 1 1 1 2 2 2 1 Calcipressin RRM_occluded PF16842.5 OAG21225.1 - 0.017 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAG21225.1 - 0.039 14.0 0.0 0.095 12.8 0.0 1.6 1 1 0 1 1 1 0 Limkain b1 DUF4523 PF15023.6 OAG21225.1 - 0.052 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Pkinase PF00069.25 OAG21226.1 - 4.8e-56 190.1 0.0 5.7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21226.1 - 2.4e-32 112.3 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CPSase_L_D2 PF02786.17 OAG21227.1 - 3.1e-81 271.9 0.2 5e-81 271.2 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAG21227.1 - 1e-69 234.3 0.0 1.8e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAG21227.1 - 3.1e-39 133.9 0.0 6.2e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG21227.1 - 7.5e-30 103.2 0.0 1.9e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAG21227.1 - 1.1e-29 103.8 0.0 2.4e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAG21227.1 - 8.1e-20 70.4 1.5 2.3e-19 69.0 1.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAG21227.1 - 5.5e-11 42.1 0.6 1.6e-05 24.6 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 OAG21227.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG21227.1 - 4e-07 29.8 0.1 8.1e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG21227.1 - 2.5e-05 24.4 0.0 7.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OAG21227.1 - 0.00024 20.7 0.0 0.00053 19.6 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 OAG21227.1 - 0.0012 19.6 0.3 0.44 11.3 0.0 3.5 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 OAG21227.1 - 0.0013 18.0 0.1 0.45 9.7 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 OAG21227.1 - 0.013 15.1 0.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 OAG21227.1 - 0.042 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 OAG21227.1 - 0.046 13.0 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 OAG21227.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 OAG21227.1 - 0.12 12.3 0.6 1.1 9.2 0.3 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.11 OAG21227.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Clathrin PF00637.20 OAG21229.1 - 5.2e-195 639.2 29.3 1.9e-32 112.1 0.2 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OAG21229.1 - 2.5e-29 101.0 0.4 2.5e-29 101.0 0.4 3.4 3 1 1 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.20 OAG21229.1 - 9.4e-12 44.6 0.5 8.1e-05 22.7 0.1 4.7 4 0 0 4 4 4 2 Clathrin propeller repeat TPR_14 PF13428.6 OAG21229.1 - 3.4e-05 24.3 7.1 10 7.2 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat Vps39_1 PF10366.9 OAG21229.1 - 0.00048 20.4 5.4 4.2 7.7 0.0 5.4 5 1 0 5 5 5 2 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 OAG21229.1 - 0.0017 17.5 2.9 0.28 10.2 0.4 3.5 3 0 0 3 3 3 2 Coatomer WD associated region TPR_2 PF07719.17 OAG21229.1 - 0.0024 17.8 0.9 6.5 7.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG21229.1 - 0.014 15.6 5.2 0.17 12.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG21229.1 - 0.014 15.4 3.4 48 4.3 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG21229.1 - 0.15 11.9 1.1 6.7 6.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Eisosome1 PF12757.7 OAG21230.1 - 1.5e-37 128.6 16.8 1.5e-37 128.6 16.8 4.2 3 1 1 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 OAG21231.1 - 3.8e-43 148.1 0.0 4.7e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAG21231.1 - 6.6e-10 38.8 0.0 9.1e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 OAG21231.1 - 0.00038 19.5 0.2 0.00048 19.2 0.2 1.4 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 OAG21231.1 - 0.00087 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAG21231.1 - 0.0012 18.7 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CMAS PF02353.20 OAG21232.1 - 2e-61 207.7 0.1 2.4e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OAG21232.1 - 1.5e-09 38.4 0.0 3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21232.1 - 9e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21232.1 - 3.4e-08 33.5 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG21232.1 - 0.0022 18.7 0.0 0.0051 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAG21232.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 OAG21232.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAG21232.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG21232.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain INSIG PF07281.12 OAG21234.1 - 9.9e-73 244.3 0.2 1.4e-72 243.8 0.2 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) eIF2_C PF09173.11 OAG21235.1 - 1.9e-34 117.8 0.3 4.3e-34 116.6 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAG21235.1 - 1.8e-23 83.1 0.1 1.2e-22 80.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAG21235.1 - 2.5e-12 47.0 0.2 5.2e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG21235.1 - 0.0036 17.4 0.0 0.0085 16.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG21235.1 - 0.0053 16.7 0.1 0.058 13.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAG21235.1 - 0.13 12.3 0.1 0.48 10.5 0.1 2.0 1 1 0 1 1 1 0 Dynamin family RhoGEF PF00621.20 OAG21236.1 - 6.8e-29 101.4 0.4 6.8e-29 101.4 0.4 2.2 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 OAG21236.1 - 1.7e-05 24.6 3.5 3.5e-05 23.6 0.1 2.5 3 0 0 3 3 3 1 BAR domain GrpE PF01025.19 OAG21236.1 - 0.047 13.4 0.9 0.1 12.2 0.9 1.5 1 0 0 1 1 1 0 GrpE Peptidase_M16_C PF05193.21 OAG21237.1 - 1.5e-21 77.2 0.0 2.5e-19 70.0 0.0 2.7 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG21237.1 - 1.8e-05 24.7 0.0 7.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) WD40 PF00400.32 OAG21238.1 - 3.5e-20 71.9 17.2 3.3e-06 27.7 0.2 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 OAG21238.1 - 6e-11 42.7 1.8 1.1e-10 41.9 0.4 2.2 2 0 0 2 2 2 1 NLE (NUC135) domain Zw10 PF06248.13 OAG21238.1 - 3.3e-08 32.6 1.9 8.4e-08 31.2 1.5 1.6 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Nup160 PF11715.8 OAG21238.1 - 3.3e-07 29.3 4.1 0.00045 19.0 1.5 3.2 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Dsl1_C PF11989.8 OAG21238.1 - 0.00031 20.5 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Trm112p PF03966.16 OAG21239.1 - 6.1e-12 45.9 0.2 3.8e-11 43.4 0.2 2.0 1 1 0 1 1 1 1 Trm112p-like protein I-EGF_1 PF18372.1 OAG21239.1 - 0.15 12.2 1.2 0.33 11.1 1.2 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 GMC_oxred_N PF00732.19 OAG21240.1 - 5.7e-34 117.8 0.0 9e-31 107.3 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG21240.1 - 1.3e-24 87.4 0.0 2.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG21240.1 - 6.4e-05 23.1 0.1 0.00015 21.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG21240.1 - 0.0094 15.2 0.0 0.018 14.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG21240.1 - 0.23 10.7 0.1 7.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PMM PF03332.13 OAG21241.1 - 2.6e-102 341.3 0.1 3e-102 341.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 OAG21241.1 - 0.0072 15.9 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 OAG21241.1 - 0.01 15.6 0.0 0.041 13.6 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OAG21241.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DNA_pol_A_exo1 PF01612.20 OAG21242.1 - 7.7e-15 55.0 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 OAG21243.1 - 2.1e-21 75.4 0.2 2.5e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG21243.1 - 0.0032 17.6 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CooT PF10133.9 OAG21243.1 - 0.039 14.2 0.2 0.12 12.6 0.0 1.9 1 1 1 2 2 2 0 CO dehydrogenase accessory protein CooT DUF150_C PF17384.2 OAG21243.1 - 0.086 13.0 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain VWA_3_C PF18571.1 OAG21243.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain HMG_box PF00505.19 OAG21244.1 - 7.1e-13 48.8 0.1 1.9e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 OAG21244.1 - 3.6e-12 46.5 0.0 6.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAG21244.1 - 9.7e-09 35.7 0.2 2.2e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 OAG21244.1 - 7.3e-07 29.2 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4634 PF15465.6 OAG21244.1 - 0.083 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) DUF3074 PF11274.8 OAG21245.1 - 1.2e-35 123.1 0.4 1.6e-35 122.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) KASH_CCD PF14662.6 OAG21246.1 - 8.2e-05 22.5 15.1 8.2e-05 22.5 15.1 4.4 3 2 3 6 6 6 1 Coiled-coil region of CCDC155 or KASH HK PF02110.15 OAG21246.1 - 0.35 10.2 2.7 4.2 6.7 1.2 2.2 1 1 1 2 2 2 0 Hydroxyethylthiazole kinase family DIOX_N PF14226.6 OAG21247.1 - 1.6e-30 106.3 0.0 3.2e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG21247.1 - 9.2e-17 61.4 0.1 1.8e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3602 PF12223.8 OAG21248.1 - 6e-19 68.4 14.4 2.6e-14 53.5 0.9 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Sec10 PF07393.11 OAG21250.1 - 5.3e-161 537.5 0.0 6.6e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 CppA_N PF14506.6 OAG21250.1 - 0.095 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 CppA N-terminal SWIB PF02201.18 OAG21251.1 - 5.4e-31 106.3 0.2 1e-30 105.4 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAG21251.1 - 1.9e-12 46.9 3.2 5.3e-12 45.5 1.7 2.2 2 0 0 2 2 2 1 DEK C terminal domain Macoilin PF09726.9 OAG21251.1 - 0.19 10.3 9.1 0.23 10.0 9.1 1.1 1 0 0 1 1 1 0 Macoilin family SRP54_N PF02881.19 OAG21251.1 - 0.69 10.2 5.2 1.6 9.0 0.5 3.1 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Tropomyosin_1 PF12718.7 OAG21253.1 - 2.8e-51 173.5 27.6 3.2e-51 173.2 27.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAG21253.1 - 3e-10 39.9 28.4 2.1e-06 27.3 5.3 2.9 1 1 1 2 2 2 2 Tropomyosin DUF3450 PF11932.8 OAG21253.1 - 0.00019 20.8 23.5 0.0025 17.1 9.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 OAG21253.1 - 0.00037 20.7 19.9 0.0077 16.4 8.6 2.4 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.9 OAG21253.1 - 0.00043 20.5 7.7 0.00043 20.5 7.7 2.4 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.9 OAG21253.1 - 0.00055 20.0 26.4 0.053 13.5 2.6 3.0 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 OAG21253.1 - 0.0015 18.5 28.3 0.014 15.4 10.2 3.4 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 OAG21253.1 - 0.0022 18.0 15.0 0.21 11.6 3.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) ADIP PF11559.8 OAG21253.1 - 0.0027 17.8 24.4 0.015 15.4 6.6 2.4 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OAG21253.1 - 0.0034 17.6 26.5 0.058 13.6 8.6 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 OAG21253.1 - 0.0042 17.4 29.3 0.047 14.1 11.9 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region BRE1 PF08647.11 OAG21253.1 - 0.0045 17.0 27.2 0.026 14.6 12.9 2.9 1 1 2 3 3 3 1 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 OAG21253.1 - 0.0046 17.2 22.6 0.45 10.8 4.1 3.1 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Taxilin PF09728.9 OAG21253.1 - 0.0052 16.0 20.9 0.095 11.9 7.9 2.1 2 0 0 2 2 2 2 Myosin-like coiled-coil protein HMMR_N PF15905.5 OAG21253.1 - 0.0058 16.1 28.5 0.087 12.3 26.2 2.0 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal DivIC PF04977.15 OAG21253.1 - 0.006 16.3 2.5 0.006 16.3 2.5 4.1 1 1 2 4 4 4 1 Septum formation initiator GAS PF13851.6 OAG21253.1 - 0.0075 15.6 24.0 0.1 11.9 14.5 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OAG21253.1 - 0.009 16.3 27.2 2.4 8.4 27.2 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 OAG21253.1 - 0.016 15.2 16.2 0.055 13.5 3.3 2.2 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 OAG21253.1 - 0.018 15.2 13.5 0.13 12.4 3.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.19 OAG21253.1 - 0.021 14.6 30.9 1.4 8.7 31.7 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 OAG21253.1 - 0.023 15.2 23.0 0.026 15.0 21.7 1.6 1 1 0 1 1 1 0 Fez1 FlaC_arch PF05377.11 OAG21253.1 - 0.027 14.9 19.0 0.84 10.1 3.2 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OAG21253.1 - 0.037 14.1 23.3 0.31 11.2 2.0 4.1 3 1 1 4 4 4 0 bZIP transcription factor Spc7 PF08317.11 OAG21253.1 - 0.049 12.5 28.1 0.31 9.9 9.3 2.0 1 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 OAG21253.1 - 0.057 14.0 17.0 0.32 11.7 1.7 3.1 2 2 1 3 3 3 0 SlyX UPF0242 PF06785.11 OAG21253.1 - 0.06 13.5 26.1 0.45 10.6 12.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spectrin PF00435.21 OAG21253.1 - 0.062 13.8 22.0 0.097 13.2 8.6 2.4 1 1 1 2 2 2 0 Spectrin repeat Lebercilin PF15619.6 OAG21253.1 - 0.066 12.9 26.8 0.1 12.2 10.5 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 OAG21253.1 - 0.068 13.0 23.6 1.8 8.4 1.2 2.6 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF812 PF05667.11 OAG21253.1 - 0.074 11.9 26.4 0.24 10.3 26.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 OAG21253.1 - 0.083 13.0 31.1 0.82 9.7 18.7 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 OAG21253.1 - 0.096 12.8 0.8 0.096 12.8 0.8 3.8 2 1 2 4 4 4 0 TolA binding protein trimerisation DUF4200 PF13863.6 OAG21253.1 - 0.12 12.8 29.9 1.1 9.6 9.2 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 OAG21253.1 - 0.15 12.4 18.3 3.8 7.9 4.1 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 OAG21253.1 - 0.15 12.4 20.7 0.18 12.2 1.7 4.0 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG17 PF04108.12 OAG21253.1 - 0.21 10.7 13.8 0.52 9.4 2.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF4407 PF14362.6 OAG21253.1 - 0.24 10.7 21.0 0.6 9.4 21.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OAG21253.1 - 0.26 11.8 28.6 2.2 8.8 11.3 3.5 1 1 2 3 3 3 0 Cell division protein ZapB FapA PF03961.13 OAG21253.1 - 0.29 9.7 21.3 0.7 8.4 7.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A EzrA PF06160.12 OAG21253.1 - 0.31 9.2 20.0 0.49 8.5 7.8 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.14 OAG21253.1 - 0.34 10.7 23.3 0.16 11.8 8.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.12 OAG21253.1 - 0.39 10.2 25.6 2.6 7.6 8.2 2.6 1 1 1 2 2 2 0 PspA/IM30 family Cep57_CLD_2 PF14197.6 OAG21253.1 - 0.4 10.8 22.5 0.26 11.4 1.8 4.4 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 Fmp27_WPPW PF10359.9 OAG21253.1 - 0.4 9.5 21.7 1 8.1 8.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 OAG21253.1 - 0.41 9.7 22.2 0.22 10.6 6.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 OAG21253.1 - 0.42 10.1 23.9 0.89 9.1 9.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein HMMR_C PF15908.5 OAG21253.1 - 0.47 10.7 14.5 1 9.6 2.7 2.8 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 OAG21253.1 - 0.53 10.8 33.2 1.7 9.2 11.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region MCC-bdg_PDZ PF10506.9 OAG21253.1 - 0.54 10.3 11.8 0.083 12.9 3.3 3.2 2 2 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome MS_channel PF00924.18 OAG21253.1 - 0.79 9.2 2.9 0.45 10.0 0.8 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel Syntaxin_2 PF14523.6 OAG21253.1 - 0.8 10.1 12.1 0.34 11.3 7.5 2.2 1 1 1 2 2 2 0 Syntaxin-like protein WXG100 PF06013.12 OAG21253.1 - 0.85 9.9 11.4 19 5.6 0.1 3.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF641 PF04859.12 OAG21253.1 - 0.88 9.9 19.3 0.32 11.3 6.2 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) IFT46_B_C PF12317.8 OAG21253.1 - 0.9 9.2 10.5 0.095 12.4 3.9 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF4201 PF13870.6 OAG21253.1 - 0.92 9.2 21.8 2.3 7.9 8.5 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.20 OAG21253.1 - 0.92 9.5 29.6 4.1 7.4 7.4 4.0 1 1 3 4 4 4 0 Prefoldin subunit Cortex-I_coil PF09304.10 OAG21253.1 - 0.96 9.7 20.3 2.8 8.2 4.5 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4795 PF16043.5 OAG21253.1 - 1.1 8.9 20.4 26 4.3 20.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF948 PF06103.11 OAG21253.1 - 1.1 9.6 11.7 3 8.2 2.7 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 OAG21253.1 - 1.1 9.2 8.1 0.66 9.9 1.3 2.3 2 1 0 2 2 2 0 Sec20 YabA PF06156.13 OAG21253.1 - 1.1 9.9 17.1 1.1 10.0 5.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Hemagglutinin PF00509.18 OAG21253.1 - 1.2 7.4 9.5 0.56 8.5 1.6 2.0 1 1 1 2 2 2 0 Haemagglutinin Fungal_TACC PF12709.7 OAG21253.1 - 1.3 9.6 24.2 5.8 7.4 2.1 4.0 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF5595 PF18077.1 OAG21253.1 - 1.4 9.0 16.5 0.35 11.0 3.1 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF5595) MAD PF05557.13 OAG21253.1 - 1.5 7.1 24.6 1.8 6.8 24.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein LPP PF04728.13 OAG21253.1 - 1.5 9.2 10.3 6.1 7.3 0.2 4.1 3 1 2 5 5 5 0 Lipoprotein leucine-zipper OmpH PF03938.14 OAG21253.1 - 1.6 9.1 26.5 1e+04 -3.2 26.5 2.3 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 OAG21253.1 - 1.6 9.1 20.7 3.4e+02 1.7 20.7 2.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMCO5 PF14992.6 OAG21253.1 - 1.7 8.1 21.8 0.48 10.0 11.3 2.0 1 1 1 2 2 2 0 TMCO5 family AAA_15 PF13175.6 OAG21253.1 - 1.7 8.2 10.4 1.9 8.1 10.4 1.0 1 0 0 1 1 1 0 AAA ATPase domain Mod_r PF07200.13 OAG21253.1 - 1.8 8.7 22.0 1.1e+02 2.8 22.0 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.6 OAG21253.1 - 1.9 7.0 21.5 23 3.5 21.5 2.1 1 1 0 1 1 1 0 AAA domain Lectin_N PF03954.14 OAG21253.1 - 1.9 8.2 12.3 12 5.6 2.5 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain YjcZ PF13990.6 OAG21253.1 - 1.9 7.8 9.3 0.37 10.1 2.1 2.0 1 1 1 2 2 2 0 YjcZ-like protein Swi5 PF07061.11 OAG21253.1 - 2 8.5 21.4 3.1 7.9 0.7 3.9 1 1 2 3 3 3 0 Swi5 KxDL PF10241.9 OAG21253.1 - 2.1 8.7 14.1 0.45 10.8 0.9 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein KELK PF15796.5 OAG21253.1 - 2.1 8.8 30.6 1.8 9.1 3.3 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Syntaxin-6_N PF09177.11 OAG21253.1 - 2.2 8.9 18.2 3.4 8.3 6.0 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DHR10 PF18595.1 OAG21253.1 - 2.3 8.3 30.5 6.5 6.8 10.7 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain XLF PF09302.11 OAG21253.1 - 2.3 8.4 8.9 1.5 9.0 1.0 2.3 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Ax_dynein_light PF10211.9 OAG21253.1 - 2.3 8.1 27.4 1.8 8.5 2.6 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain FUSC PF04632.12 OAG21253.1 - 2.5 6.5 6.5 3 6.3 6.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FH2 PF02181.23 OAG21253.1 - 2.7 7.0 16.5 0.44 9.6 3.9 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain VGPC1_C PF16799.5 OAG21253.1 - 3 7.9 12.5 1.2 9.2 0.4 3.4 2 2 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2730 PF10805.8 OAG21253.1 - 3.3 7.9 11.1 0.7 10.0 1.8 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) Prefoldin PF02996.17 OAG21253.1 - 4 7.4 22.7 3.3 7.6 2.1 3.7 2 1 2 4 4 4 0 Prefoldin subunit CtIP_N PF10482.9 OAG21253.1 - 4.3 7.4 18.4 0.41 10.7 4.5 2.7 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain XhlA PF10779.9 OAG21253.1 - 4.9 7.4 20.8 2.6 8.3 1.8 3.8 2 2 2 4 4 4 0 Haemolysin XhlA FtsX_ECD PF18075.1 OAG21253.1 - 6.1 7.5 11.0 0.43 11.2 2.5 2.6 1 1 1 2 2 2 0 FtsX extracellular domain V_ATPase_I PF01496.19 OAG21253.1 - 6.4 4.6 20.0 1.7 6.5 6.7 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CENP-K PF11802.8 OAG21253.1 - 6.7 6.2 18.3 15 5.1 18.3 1.5 1 1 0 1 1 1 0 Centromere-associated protein K ARGLU PF15346.6 OAG21253.1 - 8.4 6.3 31.7 2.9 7.7 12.0 2.1 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 HemX PF04375.14 OAG21253.1 - 10 5.3 21.5 4.3 6.5 5.9 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Nop25 PF09805.9 OAG21254.1 - 2.3e-38 131.7 12.0 2.3e-38 131.7 12.0 3.0 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) MAP7 PF05672.11 OAG21254.1 - 0.015 15.0 8.6 0.015 15.0 8.6 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Prenyltrans PF00432.21 OAG21255.1 - 8.7e-31 105.4 4.1 5.3e-07 29.3 0.0 6.1 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAG21255.1 - 0.00039 19.6 0.0 0.0019 17.4 0.0 2.2 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 OAG21255.1 - 0.069 12.2 0.0 0.97 8.4 0.0 2.5 2 1 0 2 2 2 0 A-macroglobulin TED domain RhoGAP PF00620.27 OAG21256.1 - 3.1e-17 62.8 0.2 7e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 OAG21256.1 - 3.7e-13 49.3 0.0 7.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 OAG21256.1 - 4.5e-10 39.7 0.0 3.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Syja_N PF02383.18 OAG21258.1 - 1.2e-77 261.4 0.0 1.7e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 OAG21258.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2026 PF09641.10 OAG21258.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) DUF1335 PF07056.11 OAG21258.1 - 0.21 11.7 0.1 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) RabGAP-TBC PF00566.18 OAG21259.1 - 5.8e-23 81.7 0.0 9.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 OAG21259.1 - 0.00011 20.6 11.6 0.0011 17.3 11.6 2.0 1 1 0 1 1 1 1 SBE2, cell-wall formation IGR PF09597.10 OAG21260.1 - 3.9e-25 87.7 0.0 8.1e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 IGR protein motif WD40 PF00400.32 OAG21261.1 - 5.6e-16 58.6 13.4 0.00017 22.3 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21261.1 - 8.4e-07 29.2 0.1 0.061 13.6 0.0 4.6 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG21261.1 - 0.0046 16.9 0.1 0.81 9.7 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat E3_binding PF02817.17 OAG21261.1 - 0.1 12.9 0.3 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 e3 binding domain Fungal_trans PF04082.18 OAG21262.1 - 0.042 12.9 0.1 0.042 12.9 0.1 2.1 2 1 1 3 3 3 0 Fungal specific transcription factor domain DUF4710 PF15828.5 OAG21263.1 - 1.3 9.1 4.6 0.2 11.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Zn_clus PF00172.18 OAG21264.1 - 0.001 19.1 9.3 0.0019 18.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-LYAR PF08790.11 OAG21265.1 - 8.1e-14 51.2 2.7 8.1e-14 51.2 2.7 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.13 OAG21266.1 - 2.5e-26 92.0 0.0 3.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Zn_ribbon_SprT PF17283.2 OAG21266.1 - 0.013 15.4 0.1 7.3 6.6 0.0 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Aminotran_4 PF01063.19 OAG21267.1 - 5.9e-23 81.9 0.0 7.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_C48 PF02902.19 OAG21268.1 - 9.6e-17 61.5 0.1 7.1e-16 58.7 0.1 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_47 PF01532.20 OAG21269.1 - 1.4e-169 564.8 0.0 2e-169 564.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2570 PF10828.8 OAG21269.1 - 0.16 11.8 0.3 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Lactamase_B_2 PF12706.7 OAG21270.1 - 6.4e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG21270.1 - 5.2e-15 55.7 0.4 2.2e-14 53.7 0.4 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG21270.1 - 0.023 14.7 3.6 0.15 12.1 1.5 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ribosomal_L38e PF01781.18 OAG21271.1 - 5.2e-31 106.6 2.7 6e-31 106.4 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family SAM_PNT PF02198.16 OAG21272.1 - 0.14 12.2 1.2 0.2 11.7 1.2 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF4615 PF15393.6 OAG21273.1 - 0.029 14.9 2.0 0.079 13.5 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) NDUF_B6 PF09782.9 OAG21273.1 - 0.16 12.1 0.4 0.32 11.1 0.4 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Iso_dh PF00180.20 OAG21274.1 - 1.1e-83 281.3 0.0 1.4e-83 281.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 OAG21275.1 - 6.3e-14 52.5 5.9 1.1e-13 51.7 5.9 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 OAG21275.1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21275.1 - 2.2e-09 37.9 0.0 5.9e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG21275.1 - 8.5e-05 23.2 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG21275.1 - 0.00033 20.5 0.0 0.00053 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21275.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG21275.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG21275.1 - 0.0082 15.5 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 OAG21275.1 - 0.098 13.0 0.0 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Erv26 PF04148.13 OAG21276.1 - 2.3e-92 308.5 0.1 3.2e-92 308.0 0.1 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 OAG21276.1 - 0.038 13.8 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C assembly protein NatB_MDM20 PF09797.9 OAG21277.1 - 2.8e-26 92.4 0.1 8.4e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit CBM46 PF18448.1 OAG21278.1 - 0.093 13.1 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Nuc_deoxyri_tr2 PF15891.5 OAG21279.1 - 6.6e-32 110.0 1.0 1.5e-31 108.9 0.1 2.1 3 0 0 3 3 3 1 Nucleoside 2-deoxyribosyltransferase like Ribosomal_L6e PF01159.19 OAG21279.1 - 0.13 12.8 0.7 0.6 10.7 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e zf-CSL PF05207.13 OAG21280.1 - 1.6e-15 56.6 0.2 2.5e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 OAG21280.1 - 2.4e-07 30.8 0.4 4.8e-07 29.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Macro PF01661.21 OAG21280.1 - 0.0097 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Macro domain 14-3-3 PF00244.20 OAG21281.1 - 4.1e-107 356.7 2.0 4.8e-107 356.5 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 OAG21281.1 - 0.037 12.4 1.0 0.062 11.7 1.0 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TPR_12 PF13424.6 OAG21281.1 - 0.12 12.6 0.8 3.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ima1_N PF09779.9 OAG21281.1 - 0.13 13.1 0.2 4.6 8.1 0.1 3.0 2 1 0 2 2 2 0 Ima1 N-terminal domain DUF1640 PF07798.11 OAG21282.1 - 6e-57 192.5 12.1 7.3e-57 192.2 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 OAG21282.1 - 0.1 12.0 1.6 0.2 11.0 0.1 1.8 1 1 1 2 2 2 0 GNAT acetyltransferase 2 GreA_GreB_N PF03449.15 OAG21282.1 - 0.48 10.6 9.4 1.9 8.7 9.4 2.1 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal WW PF00397.26 OAG21283.1 - 1.5e-11 44.2 0.5 4.2e-11 42.7 0.5 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 OAG21283.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Orn_Arg_deC_N PF02784.16 OAG21285.1 - 5.5e-84 281.4 0.0 7.6e-84 280.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAG21285.1 - 2e-20 72.9 0.0 2.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OAG21285.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ACC_epsilon PF13822.6 OAG21286.1 - 0.042 14.5 0.6 0.042 14.5 0.6 4.4 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit Frag1 PF10277.9 OAG21287.1 - 1.1e-44 152.6 28.3 1.1e-44 152.6 28.3 1.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family SelK_SelG PF10961.8 OAG21287.1 - 0.045 14.4 0.0 0.19 12.4 0.0 2.1 1 1 0 1 1 1 0 Selenoprotein SelK_SelG DUF4059 PF13268.6 OAG21287.1 - 0.64 10.5 0.1 0.64 10.5 0.1 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF4059) Bac_export_2 PF01312.19 OAG21287.1 - 1.2 8.2 5.3 1.7 7.7 1.2 2.2 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family G-patch_2 PF12656.7 OAG21288.1 - 4.6e-23 81.1 0.7 4.6e-23 81.1 0.7 3.1 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 OAG21288.1 - 0.013 15.3 0.5 0.032 14.1 0.5 1.8 1 0 0 1 1 1 0 G-patch domain tRNA-synt_1g PF09334.11 OAG21289.1 - 5.6e-84 282.2 0.0 3.9e-82 276.1 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAG21289.1 - 8.4e-16 57.3 1.8 7.6e-10 37.7 0.0 3.6 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG21289.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 OAG21289.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 OAG21289.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF5331 PF17265.2 OAG21289.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Sox17_18_mid PF12067.8 OAG21290.1 - 0.018 15.1 1.9 1.2e+02 2.8 0.0 4.7 5 0 0 5 5 5 0 Sox 17/18 central domain SAP PF02037.27 OAG21290.1 - 0.091 12.5 2.0 98 2.9 0.0 4.3 5 0 0 5 5 5 0 SAP domain Innate_immun PF12782.7 OAG21290.1 - 0.28 10.7 6.3 0.42 10.1 1.1 2.2 1 1 1 2 2 2 0 Invertebrate innate immunity transcript family GMAP PF06540.11 OAG21290.1 - 0.36 10.9 0.9 8.1 6.6 0.1 3.1 3 0 0 3 3 3 0 Galanin message associated peptide (GMAP) SAM_2 PF07647.17 OAG21291.1 - 1.7e-10 40.9 0.6 3.7e-10 39.8 0.3 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG21291.1 - 2e-07 31.4 0.4 4.5e-07 30.2 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAG21291.1 - 3e-05 24.4 0.0 7.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_3 PF18016.1 OAG21291.1 - 0.00074 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OAG21291.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fungal_trans_2 PF11951.8 OAG21293.1 - 8e-90 301.4 0.2 1.1e-89 301.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21293.1 - 1.1e-07 31.8 9.1 2e-07 31.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_14 PF13428.6 OAG21295.1 - 1.9e-13 50.0 0.4 0.034 15.0 0.4 6.1 6 1 1 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 OAG21295.1 - 4.2e-11 43.4 5.3 8.2e-05 22.7 0.0 4.0 1 1 3 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OAG21295.1 - 0.0068 16.9 0.0 16 6.1 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG21295.1 - 1.5 9.6 6.6 56 4.7 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat G_glu_transpept PF01019.21 OAG21296.1 - 6.2e-163 543.2 0.1 7.1e-163 543.0 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MutS_V PF00488.21 OAG21297.1 - 3.9e-72 242.2 0.1 7.5e-72 241.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG21297.1 - 1.1e-35 123.6 1.9 4e-35 121.8 1.9 2.0 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG21297.1 - 6e-29 100.6 0.1 1.3e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAG21297.1 - 3.7e-10 40.2 0.0 1.3e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG21297.1 - 7.8e-08 32.6 0.4 7.4e-07 29.4 0.2 2.8 4 0 0 4 4 4 1 MutS family domain IV DUF4911 PF16256.5 OAG21297.1 - 0.0072 16.3 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) HCR PF07111.12 OAG21298.1 - 0.011 13.8 0.4 0.014 13.5 0.4 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) MT0933_antitox PF14013.6 OAG21298.1 - 0.46 10.8 3.6 0.51 10.7 1.2 2.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein cobW PF02492.19 OAG21299.1 - 1.1e-41 142.4 0.1 1.7e-41 141.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OAG21299.1 - 0.0002 21.3 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 OAG21299.1 - 0.0016 18.7 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 OAG21299.1 - 0.0018 18.1 0.0 0.021 14.8 0.0 2.7 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAG21299.1 - 0.021 14.7 0.2 6.7 6.6 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OAG21299.1 - 0.055 13.2 0.7 0.57 10.0 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OAG21299.1 - 0.057 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 OAG21299.1 - 0.06 13.9 0.6 0.22 12.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG21299.1 - 0.087 12.7 0.1 0.71 9.7 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAG21299.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_transf_20 PF00982.21 OAG21300.1 - 1.2e-156 522.2 0.1 1.9e-156 521.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG21300.1 - 2.3e-44 151.3 0.0 3.8e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Fer2_3 PF13085.6 OAG21304.1 - 8.5e-32 109.4 0.0 1.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAG21304.1 - 1.1e-08 35.5 6.8 1.1e-08 35.5 6.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG21304.1 - 1e-07 32.3 7.4 1e-07 32.3 7.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG21304.1 - 1e-06 28.8 3.4 1e-06 28.8 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OAG21304.1 - 0.0028 18.2 4.5 0.0028 18.2 4.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAG21304.1 - 0.0045 16.9 2.8 0.013 15.4 0.4 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 OAG21304.1 - 0.36 11.0 5.4 0.48 10.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAG21304.1 - 2.6 8.3 12.0 16 5.7 10.2 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain DUF4419 PF14388.6 OAG21305.1 - 4.3e-115 384.3 0.0 5e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PMP1_2 PF08114.11 OAG21306.1 - 0.0029 17.3 0.9 0.0041 16.8 0.9 1.3 1 0 0 1 1 1 1 ATPase proteolipid family PDR_CDR PF06422.12 OAG21306.1 - 0.0063 16.4 0.1 0.0066 16.3 0.1 1.1 1 0 0 1 1 1 1 CDR ABC transporter DUF3149 PF11346.8 OAG21306.1 - 0.026 14.1 1.0 0.038 13.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) T2SSF PF00482.23 OAG21306.1 - 0.068 13.1 0.7 0.077 13.0 0.7 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F RCR PF12273.8 OAG21306.1 - 0.3 11.7 2.6 0.43 11.2 2.6 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FeoB_associated PF12669.7 OAG21306.1 - 0.4 11.1 5.7 0.39 11.2 4.8 1.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 OAG21306.1 - 1 10.3 3.0 1.7 9.6 3.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain APG5 PF04106.12 OAG21307.1 - 3.6e-65 219.8 0.0 4.9e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 PRT_C PF08372.10 OAG21309.1 - 2.9 7.6 6.7 3.2 7.5 6.7 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Aldedh PF00171.22 OAG21310.1 - 3.2e-178 593.0 1.6 3.6e-178 592.8 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG21310.1 - 0.00095 18.7 0.0 0.02 14.3 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) NAPRTase_N PF17767.1 OAG21311.1 - 0.24 11.8 0.0 0.43 11.0 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain hDGE_amylase PF14701.6 OAG21314.1 - 7.8e-182 605.3 0.0 1e-181 604.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAG21314.1 - 3e-116 388.5 0.0 4.6e-116 387.9 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OAG21314.1 - 7.5e-87 291.2 0.0 1.4e-86 290.3 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAG21314.1 - 4.7e-27 93.9 0.1 1.3e-26 92.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAG21314.1 - 0.00057 19.6 0.0 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Prenyltrans PF00432.21 OAG21315.1 - 1.3e-55 184.7 9.2 5.7e-11 42.0 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAG21315.1 - 0.16 11.0 0.0 19 4.2 0.0 3.4 2 1 2 4 4 4 0 Squalene-hopene cyclase N-terminal domain zf-C2H2 PF00096.26 OAG21316.1 - 0.11 13.0 1.1 0.48 11.0 1.1 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Far-17a_AIG1 PF04750.14 OAG21317.1 - 3.3e-45 153.9 9.1 3.9e-45 153.7 9.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_hydro_3 PF00933.21 OAG21318.1 - 6.6e-56 190.0 0.0 1.1e-55 189.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG21318.1 - 3.8e-52 177.2 0.0 1.1e-51 175.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG21318.1 - 1.4e-17 63.6 0.2 3.6e-17 62.2 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG21318.1 - 4.5e-05 23.3 0.1 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 PA14 domain 2OG-FeII_Oxy_3 PF13640.6 OAG21319.1 - 1.6e-12 48.2 0.0 2.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin PF08613.11 OAG21320.1 - 3.8e-40 137.9 9.0 5e-24 85.5 0.5 3.3 3 1 0 3 3 3 2 Cyclin Proteasome PF00227.26 OAG21321.1 - 7.3e-49 165.8 0.2 8.5e-49 165.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 OAG21322.1 - 7.1e-15 54.9 0.0 9e-11 41.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG21322.1 - 2e-10 40.8 0.0 1.6e-07 31.3 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAG21322.1 - 2.7e-06 26.3 0.4 0.061 12.0 0.0 2.7 2 1 2 4 4 4 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAG21322.1 - 1.5e-05 25.7 0.0 7.3e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAG21322.1 - 4.6e-05 23.2 0.0 0.00014 21.6 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 OAG21322.1 - 0.00033 20.3 0.0 0.95 9.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG21322.1 - 0.00037 20.0 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OAG21322.1 - 0.00053 19.6 0.0 0.0052 16.4 0.0 2.0 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 OAG21322.1 - 0.0014 18.6 0.0 0.093 12.6 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 OAG21322.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 OAG21322.1 - 0.017 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG21322.1 - 0.018 14.8 0.2 0.22 11.2 0.1 2.2 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 OAG21322.1 - 0.045 13.6 0.4 3.4 7.4 0.1 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 OAG21322.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 OAG21322.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 OAG21322.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 OAG21322.1 - 0.16 11.5 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) YTH PF04146.15 OAG21323.1 - 9.1e-63 211.1 0.0 1.5e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAG21323.1 - 1.1e-06 28.4 0.0 2.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.12 OAG21324.1 - 2.1e-22 79.1 1.5 5e-22 77.8 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG21324.1 - 1.2e-19 70.5 0.5 2.9e-19 69.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrpR_N PF06506.11 OAG21324.1 - 0.052 13.1 0.3 0.31 10.6 0.1 2.4 1 1 2 3 3 3 0 Propionate catabolism activator ADH_zinc_N_2 PF13602.6 OAG21324.1 - 0.12 13.4 0.1 0.26 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase EF-hand_4 PF12763.7 OAG21325.1 - 8e-26 90.0 2.8 9.6e-13 48.0 0.0 2.7 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 OAG21325.1 - 1.5e-07 31.0 4.3 2.2e-07 30.5 0.1 2.7 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 OAG21325.1 - 4.9e-06 26.9 67.2 5.1e-05 23.6 24.7 7.3 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 OAG21325.1 - 0.00082 19.8 0.0 1.2 9.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair E3_binding PF02817.17 OAG21325.1 - 0.2 12.0 2.3 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 e3 binding domain KxDL PF10241.9 OAG21326.1 - 0.00011 22.4 0.3 0.00014 22.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Exonuc_VII_S PF02609.16 OAG21326.1 - 0.00051 20.0 0.7 0.00051 20.0 0.7 1.8 1 1 1 2 2 2 1 Exonuclease VII small subunit Tropomyosin_1 PF12718.7 OAG21326.1 - 0.001 19.2 3.8 0.0011 19.1 3.8 1.1 1 0 0 1 1 1 1 Tropomyosin like CLZ PF16526.5 OAG21326.1 - 0.0014 19.0 2.2 0.002 18.5 2.2 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Helo_like_N PF17111.5 OAG21326.1 - 0.0043 16.5 0.4 0.0044 16.4 0.4 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins CCDC53 PF10152.9 OAG21326.1 - 0.011 16.1 2.5 0.013 15.9 2.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GCN5L1 PF06320.13 OAG21326.1 - 0.036 14.2 0.4 0.042 14.0 0.4 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) APG6_N PF17675.1 OAG21326.1 - 0.041 14.4 6.1 0.048 14.2 6.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS6_N PF14661.6 OAG21326.1 - 0.047 13.3 1.1 0.047 13.3 1.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3584 PF12128.8 OAG21326.1 - 0.048 11.2 3.5 0.054 11.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 OAG21326.1 - 0.05 13.7 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 OAG21326.1 - 0.052 13.3 0.6 0.061 13.1 0.6 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Caskin-tail PF16632.5 OAG21326.1 - 0.056 13.8 3.0 0.17 12.3 3.0 1.9 1 1 0 1 1 1 0 C-terminal region of Caskin OmpH PF03938.14 OAG21326.1 - 0.065 13.6 3.3 0.081 13.3 3.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapD PF07072.11 OAG21326.1 - 0.067 12.9 0.7 0.077 12.7 0.7 1.1 1 0 0 1 1 1 0 Cell division protein Allexi_40kDa PF05549.11 OAG21326.1 - 0.11 12.0 0.4 0.11 12.0 0.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein XhlA PF10779.9 OAG21326.1 - 0.14 12.4 1.0 0.17 12.1 1.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4471 PF14740.6 OAG21326.1 - 0.15 11.2 0.6 0.17 11.1 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) SNARE PF05739.19 OAG21326.1 - 0.17 11.9 1.6 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 SNARE domain DUF1488 PF07369.11 OAG21326.1 - 0.24 11.4 3.0 0.84 9.7 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) DUF4407 PF14362.6 OAG21326.1 - 0.49 9.7 3.7 0.5 9.7 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sugarporin_N PF11471.8 OAG21326.1 - 9.7 6.2 13.0 11 6.1 6.1 2.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension IF-2B PF01008.17 OAG21327.1 - 1.7e-72 244.0 0.8 1.9e-72 243.8 0.8 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family HlyIII PF03006.20 OAG21328.1 - 6.8e-62 209.1 22.3 8.6e-62 208.8 22.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Colicin_V PF02674.16 OAG21328.1 - 0.63 10.0 5.8 0.1 12.6 1.6 1.8 2 0 0 2 2 2 0 Colicin V production protein Ycf66_N PF07444.11 OAG21328.1 - 1.3 9.2 4.4 17 5.7 1.0 2.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus Fcf1 PF04900.12 OAG21329.1 - 7.6e-36 122.5 0.1 1.3e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAG21329.1 - 1.2e-14 54.7 1.3 8.3e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 PIN like domain PIN PF01850.21 OAG21329.1 - 0.14 12.7 1.0 8.3 6.9 0.6 2.3 1 1 0 1 1 1 0 PIN domain FSA_C PF10479.9 OAG21330.1 - 3.5 5.6 6.0 4.8 5.2 6.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DnaJ PF00226.31 OAG21331.1 - 1e-09 38.4 1.6 7e-09 35.7 1.6 2.3 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.19 OAG21332.1 - 5.5e-38 129.8 1.4 7.7e-38 129.3 1.4 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 OAG21332.1 - 0.019 13.7 0.7 0.022 13.5 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DnaJ PF00226.31 OAG21335.1 - 2.9e-21 75.4 4.2 4.7e-21 74.7 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 OAG21335.1 - 9.9 6.4 14.3 0.18 12.0 4.5 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide ArfGap PF01412.18 OAG21336.1 - 1.7e-36 124.8 0.0 1.7e-36 124.8 0.0 2.5 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.31 OAG21336.1 - 0.0058 16.5 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain FAD_binding_4 PF01565.23 OAG21338.1 - 7.3e-27 93.8 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG21338.1 - 4e-09 36.5 0.0 8.1e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain DUF4100 PF13352.6 OAG21339.1 - 1.6 8.5 7.7 0.12 12.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) Glyco_hydro_2_C PF02836.17 OAG21340.1 - 1.1e-103 346.5 0.3 1.7e-103 345.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OAG21340.1 - 1.8e-67 227.5 0.0 2.9e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OAG21340.1 - 3.1e-41 141.1 0.2 6.9e-41 140.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OAG21340.1 - 2.7e-18 66.2 0.0 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OAG21340.1 - 1.2e-11 45.2 0.1 3.6e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG21340.1 - 0.003 18.1 0.0 0.011 16.3 0.0 2.0 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Sugar_tr PF00083.24 OAG21341.1 - 1.1e-84 284.9 26.1 1.4e-84 284.6 26.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21341.1 - 2.9e-39 135.0 51.9 8.1e-32 110.5 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG21341.1 - 2.6e-06 26.2 2.1 2.6e-06 26.2 2.1 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG21341.1 - 0.062 11.6 15.9 0.15 10.3 1.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAG21342.1 - 2.1e-75 253.9 0.0 3.1e-75 253.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG21342.1 - 1.3e-06 29.3 0.0 3.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 OAG21342.1 - 0.00067 19.3 1.1 0.00067 19.3 1.1 6.2 8 0 0 8 8 8 1 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 OAG21342.1 - 0.0015 18.8 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PilZ_2 PF16823.5 OAG21342.1 - 0.11 12.7 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Atypical PilZ domain, cyclic di-GMP receptor Hexapep_2 PF14602.6 OAG21342.1 - 1.3 8.8 12.2 1.4 8.7 1.5 4.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF4747 PF15931.5 OAG21343.1 - 0.0064 16.2 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4747) HABP4_PAI-RBP1 PF04774.15 OAG21343.1 - 0.34 11.8 7.9 0.083 13.7 2.0 2.2 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family MFS_1 PF07690.16 OAG21346.1 - 1.4e-24 86.7 36.3 4e-24 85.2 27.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4448 PF14610.6 OAG21346.1 - 0.12 12.1 1.9 7.2 6.3 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4448) Phage_holin_7_1 PF16081.5 OAG21346.1 - 0.25 11.5 8.3 5.3 7.2 0.5 2.6 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sugar_tr PF00083.24 OAG21346.1 - 0.58 8.9 36.2 22 3.7 36.2 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter TPR_2 PF07719.17 OAG21347.1 - 1.3e-09 37.4 2.4 0.00028 20.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG21347.1 - 1.1e-06 29.2 2.0 0.00041 20.9 0.5 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG21347.1 - 1.4e-06 27.8 0.3 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG21347.1 - 8.6e-06 26.0 0.4 0.02 15.2 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG21347.1 - 2.6e-05 24.1 0.1 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG21347.1 - 0.0046 17.4 0.6 0.0096 16.4 0.1 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG21347.1 - 0.029 15.2 4.8 0.12 13.3 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat U-box PF04564.15 OAG21348.1 - 5.6e-17 61.7 0.2 1.5e-16 60.3 0.2 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OAG21348.1 - 0.031 14.1 0.6 0.17 11.7 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Par3_HAL_N_term PF12053.8 OAG21348.1 - 0.042 14.1 0.2 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins zf-NOSIP PF15906.5 OAG21348.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Cu_amine_oxid PF01179.20 OAG21350.1 - 6.5e-160 532.5 0.0 8.5e-160 532.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Mito_carr PF00153.27 OAG21350.1 - 2.5e-56 187.6 0.1 3.1e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cu_amine_oxidN3 PF02728.16 OAG21350.1 - 3.9e-19 68.9 0.2 7.1e-19 68.1 0.2 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAG21350.1 - 3.7e-11 43.1 0.0 6.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cellulase PF00150.18 OAG21351.1 - 5.8e-19 68.6 6.5 8.3e-19 68.1 6.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RFX_DNA_binding PF02257.15 OAG21352.1 - 1.3e-27 96.2 0.0 2.8e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain RXLR PF16810.5 OAG21352.1 - 0.032 14.7 0.3 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity TFIIA PF03153.13 OAG21352.1 - 7.8 6.4 19.5 1.5 8.8 15.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TB2_DP1_HVA22 PF03134.19 OAG21353.1 - 1.4e-26 92.3 9.7 1.4e-26 92.3 9.7 1.6 1 1 1 2 2 2 2 TB2/DP1, HVA22 family BAR PF03114.18 OAG21354.1 - 1.8e-61 207.8 4.1 2.2e-61 207.6 4.1 1.1 1 0 0 1 1 1 1 BAR domain FliD_N PF02465.18 OAG21354.1 - 1.1 9.9 6.7 1.4 9.7 0.4 2.7 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus tRNA-synt_1b PF00579.25 OAG21355.1 - 3.4e-69 233.4 0.0 4.8e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.13 OAG21355.1 - 0.0077 16.8 1.8 0.02 15.5 1.8 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) UQ_con PF00179.26 OAG21356.1 - 4.5e-38 130.0 0.1 6.2e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 OAG21356.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 OAG21356.1 - 0.038 14.3 0.5 0.15 12.4 0.5 2.1 1 1 0 1 1 1 0 RWD domain CorA PF01544.18 OAG21357.1 - 5.6e-46 157.2 0.0 8.3e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 OAG21358.1 - 9.7e-31 105.7 0.1 1.3e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 OAG21359.1 - 2.6e-25 88.5 13.1 3.5e-25 88.1 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG21359.1 - 3.1e-17 62.4 10.0 3.9e-17 62.1 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAG21359.1 - 1.7e-06 28.2 14.5 6.6e-05 23.2 14.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG21359.1 - 8.3e-05 22.4 3.5 8.3e-05 22.4 3.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG21359.1 - 0.0012 18.7 11.9 0.022 14.6 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG21359.1 - 0.13 12.1 10.8 0.44 10.5 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG21359.1 - 0.26 11.0 15.8 24 4.8 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OAG21359.1 - 0.41 10.7 7.8 1.5 8.9 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 OAG21359.1 - 0.46 10.7 9.4 2.4 8.4 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OAG21359.1 - 0.51 10.0 14.9 80 3.0 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 OAG21360.1 - 6.3e-09 35.4 5.5 6.3e-09 35.4 5.5 4.3 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Glycos_transf_1 PF00534.20 OAG21363.1 - 8.8e-21 74.2 0.0 3.7e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG21363.1 - 1.3e-13 51.5 0.0 3.8e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAG21363.1 - 0.00029 21.2 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 OAG21363.1 - 0.16 10.6 0.0 0.42 9.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 20 B1 PF02246.15 OAG21363.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein L b1 domain WD40 PF00400.32 OAG21364.1 - 4e-57 188.9 15.1 1.1e-08 35.5 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21364.1 - 3.7e-16 59.2 0.1 0.00026 21.2 0.0 5.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 OAG21364.1 - 1.7e-14 53.9 6.2 3.3e-14 52.9 6.2 1.5 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 OAG21364.1 - 3.3e-09 36.5 0.0 0.013 14.8 0.0 4.7 3 1 2 5 5 5 2 WD40-like domain Nup160 PF11715.8 OAG21364.1 - 5.8e-05 21.9 0.7 0.14 10.8 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG21364.1 - 0.00052 19.1 0.1 2.3 7.1 0.0 4.1 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAG21364.1 - 0.017 13.8 0.2 9.9 4.8 0.1 3.5 2 1 1 3 3 3 0 Nup133 N terminal like BBP1_C PF15272.6 OAG21364.1 - 0.025 14.4 0.6 0.039 13.8 0.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Nuc_N PF14448.6 OAG21364.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Nuclease N terminal Golgin_A5 PF09787.9 OAG21364.1 - 0.14 11.6 3.0 0.21 11.0 3.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nbas_N PF15492.6 OAG21364.1 - 0.16 11.3 0.1 12 5.1 0.0 2.7 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 OAG21364.1 - 0.17 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain SHE3 PF17078.5 OAG21364.1 - 0.26 11.0 1.8 0.8 9.4 0.7 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 OAG21364.1 - 0.41 11.1 2.1 0.49 10.9 0.8 1.7 2 0 0 2 2 2 0 Cell division protein ZapB CLZ PF16526.5 OAG21364.1 - 0.91 9.9 2.5 1.8 9.0 2.5 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Na_H_Exchanger PF00999.21 OAG21365.1 - 8.8e-74 248.6 33.4 1.1e-73 248.3 33.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 OAG21365.1 - 6.6 6.3 8.2 0.93 9.1 2.1 2.2 1 1 0 2 2 2 0 PepSY-associated TM region NiFe_hyd_3_EhaA PF17367.2 OAG21365.1 - 8.2 6.6 18.3 1.6 8.9 2.6 4.1 3 1 2 5 5 5 0 NiFe-hydrogenase-type-3 Eha complex subunit A MFS_2 PF13347.6 OAG21366.1 - 9.6e-13 47.5 16.3 1.1e-11 44.0 4.1 3.5 4 0 0 4 4 4 3 MFS/sugar transport protein PUCC PF03209.15 OAG21366.1 - 0.00012 21.2 3.6 0.00015 20.9 0.9 2.2 2 0 0 2 2 2 1 PUCC protein Glyco_hydro_6 PF01341.17 OAG21367.1 - 5.3e-102 341.6 0.8 6.5e-102 341.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.14 OAG21367.1 - 0.031 13.1 0.1 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Pox_A31 PF05771.11 OAG21368.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A31 protein AA_permease_2 PF13520.6 OAG21370.1 - 5.4e-48 163.9 50.6 7.1e-48 163.5 50.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG21370.1 - 1.4e-25 89.9 47.5 2.4e-25 89.1 47.5 1.3 1 1 0 1 1 1 1 Amino acid permease Rit1_C PF17184.4 OAG21371.1 - 5.6e-106 353.9 0.0 8.2e-106 353.4 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 OAG21371.1 - 9.4e-34 116.0 0.0 2e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF3387 PF11867.8 OAG21371.1 - 0.26 10.6 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Acyltransferase PF01553.21 OAG21372.1 - 2.3e-27 95.3 0.1 4.5e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 OAG21372.1 - 1.2e-12 47.7 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 OAG21373.1 - 1.2e-49 169.1 0.0 2.2e-49 168.3 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAG21373.1 - 0.045 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Gly_transf_sug PF04488.15 OAG21374.1 - 1.1e-09 38.8 0.0 1.9e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OAG21374.1 - 7.2e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein SKG6 PF08693.10 OAG21375.1 - 0.00012 21.3 0.1 0.00026 20.3 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 OAG21375.1 - 0.0046 17.2 0.1 0.0089 16.3 0.1 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MGC-24 PF05283.11 OAG21375.1 - 0.02 15.4 1.0 0.032 14.7 1.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin IQCJ-SCHIP1 PF15157.6 OAG21375.1 - 5.1 6.9 7.2 8.7 6.2 7.2 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Tmemb_9 PF05434.11 OAG21376.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 TMEM9 GMC_oxred_C PF05199.13 OAG21377.1 - 4.1e-29 101.9 0.0 7.6e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG21377.1 - 2.1e-27 96.3 0.0 5.8e-26 91.5 0.0 2.1 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG21377.1 - 0.00096 18.5 0.0 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG21377.1 - 0.0026 17.9 0.1 0.0064 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG21377.1 - 0.0051 16.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG21377.1 - 0.021 13.9 0.2 0.038 13.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG21377.1 - 0.026 13.8 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 OAG21377.1 - 0.063 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG21377.1 - 0.097 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 OAG21377.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pro_isomerase PF00160.21 OAG21378.1 - 4.1e-42 144.1 0.1 9.8e-42 142.9 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SurA_N_2 PF13623.6 OAG21378.1 - 0.056 13.3 0.3 2 8.3 0.0 2.9 4 0 0 4 4 4 0 SurA N-terminal domain PHD_3 PF13922.6 OAG21378.1 - 0.4 11.1 1.4 0.63 10.5 0.4 1.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx MBOAT PF03062.19 OAG21379.1 - 4.1e-57 194.1 7.4 4.1e-57 194.1 7.4 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Amidase PF01425.21 OAG21381.1 - 4.2e-86 289.7 0.0 2.6e-85 287.1 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG21382.1 - 4.4e-25 88.3 13.3 3.4e-21 75.6 9.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG21383.1 - 0.00085 19.4 10.0 0.0017 18.4 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt4 PF06093.13 OAG21383.1 - 4.4 7.5 5.2 10 6.3 5.2 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger S1-P1_nuclease PF02265.16 OAG21384.1 - 8.8e-73 245.2 0.5 1.1e-72 244.9 0.5 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DER1 PF04511.15 OAG21385.1 - 1e-44 152.8 6.8 1.2e-44 152.5 6.8 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 OAG21386.1 - 1.2e-42 145.3 0.3 1.5e-42 145.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAG21386.1 - 2.5e-06 27.8 0.1 3.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG21386.1 - 1.1e-05 25.5 0.1 1.6e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAG21386.1 - 0.0025 18.1 0.5 0.0049 17.1 0.5 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG21386.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Peptidase_S10 PF00450.22 OAG21387.1 - 4.7e-85 286.5 1.6 6.6e-85 286.0 1.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 OAG21389.1 - 2.4e-36 125.4 58.4 9.6e-35 120.1 58.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 OAG21390.1 - 3.1e-05 23.8 0.0 9.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG21390.1 - 0.048 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain DUF1929 PF09118.11 OAG21391.1 - 4.7e-24 84.5 1.7 6.6e-24 84.0 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 OAG21391.1 - 1.1e-23 83.8 3.2 2.9e-23 82.4 3.2 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 OAG21391.1 - 1e-16 60.5 6.1 6.3e-08 32.6 0.1 5.5 4 2 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OAG21391.1 - 1.9e-12 46.6 2.9 0.0021 17.6 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 OAG21391.1 - 1.3e-07 31.5 6.9 0.00054 19.9 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG21391.1 - 2.6e-07 30.3 1.0 0.78 9.8 0.4 5.7 5 1 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 OAG21391.1 - 2.5e-06 26.9 0.2 0.017 14.3 0.2 2.7 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 OAG21391.1 - 0.15 12.4 2.1 0.57 10.5 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Sds3 PF08598.11 OAG21392.1 - 5.5e-17 62.5 0.1 5.5e-17 62.5 0.1 1.8 2 0 0 2 2 2 1 Sds3-like DUF1487 PF07368.11 OAG21392.1 - 0.021 14.3 0.5 0.13 11.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) DUF4094 PF13334.6 OAG21392.1 - 0.043 14.2 1.4 0.097 13.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FXMRP1_C_core PF12235.8 OAG21392.1 - 1.8 9.2 16.3 2.1 9.0 4.3 3.7 3 1 1 4 4 4 0 Fragile X-related 1 protein core C terminal RRM_1 PF00076.22 OAG21393.1 - 4.6e-16 58.4 0.3 1.3e-11 44.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BSP_II PF05432.11 OAG21393.1 - 0.45 10.2 45.6 1.2 8.7 45.6 1.8 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CBFB_NFYA PF02045.15 OAG21394.1 - 2e-28 98.7 3.3 5.9e-28 97.3 3.3 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 OAG21394.1 - 0.059 13.4 31.1 0.078 13.0 31.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4611 PF15387.6 OAG21394.1 - 5.5 7.3 9.6 6.9 7.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SHD1 PF03983.12 OAG21395.1 - 6.3e-35 118.8 0.1 1.1e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 OAG21395.1 - 1.2e-33 114.4 8.3 1.2e-12 47.2 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAG21395.1 - 7.6e-31 105.7 4.9 5.6e-10 38.9 0.1 4.0 3 0 0 3 3 3 3 Variant SH3 domain MFS_1 PF07690.16 OAG21395.1 - 4.2e-28 98.3 29.1 6.1e-28 97.7 29.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SH3_2 PF07653.17 OAG21395.1 - 1.8e-25 88.4 0.0 2.9e-08 33.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 OAG21395.1 - 1.5e-06 28.5 30.4 1.5e-06 28.5 30.4 6.8 2 1 4 6 6 6 3 Domain of unknown function (DUF1720) SAM_4 PF18017.1 OAG21395.1 - 0.077 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 OAG21395.1 - 0.082 13.2 5.0 2.1 8.7 0.7 3.0 3 0 0 3 3 3 0 Bacterial SH3 domain SRP-alpha_N PF04086.13 OAG21395.1 - 0.35 10.7 7.0 1.1 9.1 7.0 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CYSTM PF12734.7 OAG21396.1 - 6.2e-10 39.2 27.1 6.2e-10 39.2 27.1 4.6 2 1 1 3 3 3 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 OAG21396.1 - 0.18 12.5 2.1 0.21 12.2 2.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region STT3 PF02516.14 OAG21398.1 - 7.4e-146 486.9 37.3 5.4e-141 470.9 34.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit GET2 PF08690.10 OAG21399.1 - 0.069 12.8 10.1 0.21 11.2 10.1 1.8 1 0 0 1 1 1 0 GET complex subunit GET2 zf-C2H2_aberr PF17017.5 OAG21399.1 - 3.5 7.7 15.7 0.44 10.7 2.4 3.8 2 2 2 4 4 4 0 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG21400.1 - 6.3e-05 23.2 24.2 0.096 13.2 0.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG21400.1 - 2.9 8.6 13.5 1.9 9.2 2.0 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF4072 PF13284.6 OAG21401.1 - 0.092 13.2 0.0 0.38 11.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) SPC25 PF06703.11 OAG21402.1 - 5.3e-54 182.4 0.0 6.2e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 OAG21403.1 - 1.5e-57 194.1 1.1 1.9e-57 193.7 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EI24 PF07264.11 OAG21403.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) TFIIF_alpha PF05793.12 OAG21404.1 - 0.014 14.0 4.3 0.02 13.5 4.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2_4 PF13894.6 OAG21404.1 - 0.044 14.6 0.3 0.044 14.6 0.3 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG21404.1 - 0.23 12.0 12.5 0.52 10.9 0.2 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Kp4 PF09044.10 OAG21405.1 - 7.5e-23 81.0 4.1 1e-22 80.5 4.1 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 OAG21405.1 - 0.0005 20.8 4.4 0.0016 19.2 4.8 1.7 1 1 1 2 2 2 2 Meiotically up-regulated gene family DUF953 PF06110.11 OAG21405.1 - 0.041 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DZR PF12773.7 OAG21405.1 - 0.98 9.5 9.7 0.58 10.2 2.5 2.4 2 1 0 2 2 2 0 Double zinc ribbon PRKCSH PF07915.13 OAG21406.1 - 1.7e-19 70.6 1.0 1.7e-19 70.6 1.0 2.5 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OAG21406.1 - 0.001 18.8 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF295 PF03478.18 OAG21406.1 - 0.083 12.5 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Pkinase PF00069.25 OAG21408.1 - 2.8e-67 226.9 0.0 4.1e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21408.1 - 6.2e-36 124.0 0.0 9.6e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG21408.1 - 3.5e-08 33.7 0.5 4.1e-07 30.2 0.2 2.4 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 OAG21408.1 - 0.00036 19.9 0.1 0.00062 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 OAG21408.1 - 0.00043 20.5 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 OAG21408.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG21408.1 - 0.027 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OAG21408.1 - 0.12 11.9 0.3 0.22 11.1 0.3 1.3 1 0 0 1 1 1 0 RIO1 family Gly_transf_sug PF04488.15 OAG21409.1 - 4.1e-18 65.8 0.1 1.4e-17 64.1 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif MFS_1 PF07690.16 OAG21410.1 - 9.5e-30 103.7 30.9 9.5e-30 103.7 30.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 OAG21410.1 - 0.0073 14.3 0.0 0.011 13.7 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YrhK PF14145.6 OAG21410.1 - 0.054 13.4 9.1 0.69 9.8 0.3 4.3 3 1 1 4 4 4 0 YrhK-like protein DUF2149 PF09919.9 OAG21410.1 - 0.062 13.6 0.1 0.3 11.4 0.2 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) DUF3671 PF12420.8 OAG21410.1 - 7.5 6.7 9.8 2.8 8.0 0.6 4.0 4 2 0 4 4 4 0 Protein of unknown function GFO_IDH_MocA_C PF02894.17 OAG21411.1 - 1.6e-18 66.8 0.2 3.8e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 OAG21411.1 - 9.4e-18 65.2 0.0 1.7e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Lactamase_B_2 PF12706.7 OAG21412.1 - 5.1e-09 35.9 0.0 1.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG21412.1 - 0.00014 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 OAG21412.1 - 0.00014 22.0 0.1 0.00043 20.4 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 OAG21412.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain SprT-like PF10263.9 OAG21413.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Sel1 PF08238.12 OAG21414.1 - 1.3e-36 124.2 32.0 1.4e-06 28.8 0.4 11.4 11 0 0 11 11 11 8 Sel1 repeat Zea_mays_MuDR PF05928.11 OAG21414.1 - 0.018 14.6 0.2 0.034 13.8 0.2 1.4 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) SARAF PF06682.12 OAG21414.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis OPA3 PF07047.12 OAG21414.1 - 0.064 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Phage_holin_2_4 PF16082.5 OAG21414.1 - 0.093 12.5 0.7 0.3 10.8 0.7 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TPR_6 PF13174.6 OAG21414.1 - 1 10.1 13.1 99 3.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG21414.1 - 3.9 7.9 6.0 27 5.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG21414.1 - 5.2 7.1 18.1 2.2 8.3 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAG21415.1 - 2.8e-37 128.5 46.2 4.1e-37 127.9 46.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG21415.1 - 4.5e-13 48.9 11.3 4.5e-13 48.9 11.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG21415.1 - 1.1e-06 27.5 20.2 1.6e-06 26.9 20.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAG21415.1 - 0.46 9.4 23.3 1 8.3 8.4 2.4 2 0 0 2 2 2 0 PUCC protein TMEM135_C_rich PF15982.5 OAG21415.1 - 3.6 8.2 7.5 0.56 10.8 0.4 3.0 3 1 0 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF4094 PF13334.6 OAG21416.1 - 0.081 13.4 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) tRNA-synt_2b PF00587.25 OAG21417.1 - 9e-36 123.5 0.0 3.2e-34 118.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG21417.1 - 1.3e-08 34.8 0.0 2.7e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Anticodon binding domain HisK_N PF09385.10 OAG21418.1 - 0.071 13.1 0.5 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 Histidine kinase N terminal TraT PF05818.12 OAG21418.1 - 0.3 10.7 1.4 0.73 9.5 1.4 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Methyltransf_16 PF10294.9 OAG21419.1 - 0.096 12.4 0.0 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase HLH PF00010.26 OAG21420.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Membr_traf_MHD PF10540.9 OAG21421.1 - 5.5e-21 75.3 1.0 3.7e-18 66.1 0.3 3.0 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAG21421.1 - 2.7e-15 56.5 0.0 7.2e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 OAG21421.1 - 2.7e-08 32.9 3.9 5.4e-08 31.9 1.6 2.2 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DUF1996 PF09362.10 OAG21424.1 - 2.6e-83 279.6 0.2 3.1e-83 279.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NDUF_B8 PF05821.11 OAG21425.1 - 3.3e-05 23.8 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 OAG21426.1 - 6.2e-63 212.6 0.0 1.1e-62 211.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG21426.1 - 1.2e-18 67.5 0.0 2.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 OAG21426.1 - 5e-10 39.6 1.7 5e-10 39.6 1.7 2.9 2 0 0 2 2 2 1 HSA ResIII PF04851.15 OAG21426.1 - 9.9e-10 38.7 0.1 6.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG21426.1 - 3.9e-05 23.5 0.0 9.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OAG21426.1 - 0.0091 15.6 0.0 0.029 14.0 0.0 1.9 1 0 0 1 1 1 1 DEAD_2 Annexin PF00191.20 OAG21426.1 - 0.055 13.5 0.0 0.69 10.0 0.0 2.7 2 0 0 2 2 2 0 Annexin ABC_membrane_2 PF06472.15 OAG21427.1 - 3.2e-92 308.7 1.0 3.6e-92 308.6 0.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG21427.1 - 1.5e-14 54.7 0.0 3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 OAG21427.1 - 0.0056 17.2 0.3 0.47 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG21427.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 OAG21427.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain THOC7 PF05615.13 OAG21427.1 - 0.062 13.6 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 End3 PF12761.7 OAG21427.1 - 0.074 13.2 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 AAA_16 PF13191.6 OAG21427.1 - 0.075 13.4 0.7 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAG21427.1 - 0.094 12.5 0.0 0.31 10.8 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OAG21427.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3824 PF12868.7 OAG21427.1 - 0.18 12.5 0.0 0.18 12.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) Zn_clus PF00172.18 OAG21428.1 - 9.9e-08 32.0 7.8 2.1e-07 31.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 OAG21428.1 - 3.6e-06 26.7 6.3 2e-05 24.2 6.3 2.2 1 1 0 1 1 1 1 Aflatoxin regulatory protein UPF0688 PF15772.5 OAG21428.1 - 0.038 14.3 0.2 0.059 13.6 0.2 1.3 1 0 0 1 1 1 0 UPF0688 family HEM4 PF02602.15 OAG21428.1 - 0.064 12.6 0.0 0.17 11.2 0.0 1.6 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD EcKinase PF02958.20 OAG21428.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Ada3 PF10198.9 OAG21429.1 - 4.5e-44 149.8 0.1 4.5e-44 149.8 0.1 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.6 OAG21430.1 - 5.6e-11 42.6 8.9 1e-10 41.8 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG21430.1 - 2.8e-08 33.3 5.7 5.2e-08 32.5 5.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG21430.1 - 7.3e-07 28.9 9.3 1.4e-06 28.1 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG21430.1 - 1.1e-05 25.3 6.3 1.8e-05 24.6 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG21430.1 - 1.7e-05 24.7 4.5 1.7e-05 24.7 4.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG21430.1 - 5.5e-05 23.1 3.2 0.00012 22.1 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG21430.1 - 7.4e-05 22.5 7.9 0.00013 21.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG21430.1 - 0.0024 17.7 4.7 0.0045 16.8 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG21430.1 - 0.0029 17.8 11.5 0.014 15.7 11.3 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG21430.1 - 0.0082 15.9 5.7 0.015 15.1 5.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OAG21430.1 - 0.016 15.1 11.0 0.29 11.0 10.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF4481 PF14800.6 OAG21430.1 - 0.046 13.2 0.2 0.068 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) zf-C3HC4_4 PF15227.6 OAG21430.1 - 0.37 11.0 5.7 0.85 9.8 5.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 OAG21430.1 - 2.5 7.8 4.8 5.1 6.8 4.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 OAG21430.1 - 9.9 5.9 6.8 0.99 9.1 2.0 1.8 2 0 0 2 2 2 0 P-11 zinc finger DUF4360 PF14273.6 OAG21431.1 - 1.9e-51 174.5 0.4 2.2e-51 174.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Aldedh PF00171.22 OAG21432.1 - 5.5e-153 509.8 0.0 6.7e-153 509.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG21432.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_hydro_10 PF00331.20 OAG21433.1 - 2.1e-97 326.1 0.1 2.5e-97 325.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 OAG21433.1 - 8.8e-10 38.4 11.1 8.8e-10 38.4 11.1 2.6 4 0 0 4 4 4 1 Fungal cellulose binding domain Histidinol_dh PF00815.20 OAG21434.1 - 1.3e-159 531.6 4.9 2.2e-159 530.8 4.9 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAG21434.1 - 2.9e-24 84.7 0.0 6.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAG21434.1 - 3.6e-15 56.2 0.7 1.6e-14 54.1 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAG21434.1 - 0.15 12.2 0.3 0.45 10.7 0.3 1.8 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Peptidase_C10 PF01640.17 OAG21434.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase C10 family EHN PF06441.12 OAG21435.1 - 3.5e-36 123.8 0.6 8.1e-36 122.7 0.6 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG21435.1 - 2.1e-07 30.9 0.0 5.2e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.11 OAG21436.1 - 5e-114 381.8 0.4 5.9e-114 381.6 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG21436.1 - 1.5e-05 24.4 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG21436.1 - 0.0029 17.3 0.6 0.0052 16.5 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Mqo PF06039.15 OAG21437.1 - 0.14 10.6 0.1 0.21 10.1 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lipocalin_5 PF13924.6 OAG21438.1 - 1.7e-33 115.4 0.0 2.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain PPP4R2 PF09184.11 OAG21439.1 - 9.6e-07 28.7 13.9 2.8e-05 23.8 13.9 2.4 1 1 0 1 1 1 1 PPP4R2 DUF5353 PF17304.2 OAG21440.1 - 0.32 10.8 2.9 4.9 7.0 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5353) Phtf-FEM1B_bdg PF12129.8 OAG21440.1 - 0.61 9.9 11.5 0.28 11.0 5.6 2.3 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF1129 PF06570.11 OAG21440.1 - 1.6 8.2 17.8 0.018 14.6 4.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF2178 PF09946.9 OAG21440.1 - 2.2 8.5 12.7 0.12 12.5 4.8 2.8 2 1 0 3 3 3 0 Predicted membrane protein (DUF2178) GWT1 PF06423.12 OAG21440.1 - 3.5 7.7 11.4 0.82 9.8 0.2 2.9 1 1 1 2 2 2 0 GWT1 Mpv17_PMP22 PF04117.12 OAG21441.1 - 3.1e-21 75.3 1.1 5e-21 74.7 1.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 OAG21442.1 - 5.2e-65 219.4 0.0 8.4e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21442.1 - 2.3e-36 125.4 0.0 1.5e-30 106.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG21442.1 - 6.3e-06 25.7 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG21442.1 - 0.0024 17.8 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG21442.1 - 0.021 13.8 0.2 0.034 13.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OAG21442.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OAG21442.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEXIM PF15313.6 OAG21442.1 - 1.2 9.3 8.8 0.074 13.2 2.7 2.0 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Pkinase_fungal PF17667.1 OAG21442.1 - 1.2 7.8 5.2 1.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase Pyr_redox_2 PF07992.14 OAG21443.1 - 6.1e-54 183.2 1.3 8.1e-54 182.8 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAG21443.1 - 8.7e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAG21443.1 - 8.4e-15 55.1 1.1 8.4e-15 55.1 1.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG21443.1 - 2.3e-08 33.6 0.5 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 OAG21443.1 - 9.1e-07 29.4 0.0 4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.6 OAG21443.1 - 3.7e-06 26.8 0.1 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_7 PF13241.6 OAG21443.1 - 0.024 15.1 0.8 0.84 10.1 0.0 2.4 1 1 1 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 OAG21443.1 - 0.074 12.6 0.4 0.2 11.2 0.2 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OAG21443.1 - 0.13 11.5 1.4 14 4.9 0.8 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OAG21443.1 - 0.2 11.7 0.7 8.9 6.3 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Redoxin PF08534.10 OAG21444.1 - 5e-18 65.2 0.0 6e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG21444.1 - 2.3e-10 40.5 0.0 2.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family SKG6 PF08693.10 OAG21445.1 - 0.01 15.2 1.1 0.018 14.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EB PF01683.18 OAG21445.1 - 0.012 15.9 1.0 0.02 15.1 1.0 1.3 1 0 0 1 1 1 0 EB module Glyco_hydro_31 PF01055.26 OAG21446.1 - 9.1e-150 499.7 3.1 1.2e-149 499.3 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG21446.1 - 1.2e-30 106.1 0.0 2.1e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG21446.1 - 2.7e-05 24.4 0.9 0.00025 21.3 0.4 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like FAM199X PF15814.5 OAG21447.1 - 0.05 12.7 2.9 0.067 12.2 2.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X Gly-zipper_Omp PF13488.6 OAG21447.1 - 0.28 11.2 31.0 0.042 13.8 20.8 2.5 1 1 1 2 2 2 0 Glycine zipper Sporozoite_P67 PF05642.11 OAG21447.1 - 0.49 8.4 14.0 0.55 8.2 14.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraT PF05818.12 OAG21447.1 - 0.62 9.7 3.7 1 9.0 3.7 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.6 OAG21447.1 - 0.84 9.5 22.9 2 8.3 1.2 2.5 2 0 0 2 2 2 0 Glycine-zipper domain NPR2 PF06218.11 OAG21448.1 - 3.5e-163 543.4 0.0 6.6e-163 542.5 0.0 1.5 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.13 OAG21448.1 - 0.00017 20.6 2.3 0.016 14.0 0.0 3.4 4 0 0 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 YlqD PF11068.8 OAG21451.1 - 0.1 13.0 6.6 0.22 11.9 6.6 1.5 1 0 0 1 1 1 0 YlqD protein Spc24 PF08286.11 OAG21451.1 - 0.4 10.9 3.0 0.82 9.9 3.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 tRNA-synt_2 PF00152.20 OAG21452.1 - 1.3e-56 192.0 0.0 1.7e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG21452.1 - 2.6e-09 36.9 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG21452.1 - 4.4e-07 29.6 0.1 5.9e-05 22.7 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ADH_N PF08240.12 OAG21453.1 - 6.3e-27 93.6 4.5 1e-26 93.0 3.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG21453.1 - 1.9e-07 31.1 0.0 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG21453.1 - 0.014 15.3 0.1 0.014 15.3 0.1 2.0 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 OAG21453.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF4879 PF16219.5 OAG21453.1 - 0.029 14.6 0.2 0.85 9.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4879) FANCL_C PF11793.8 OAG21453.1 - 0.047 13.9 0.9 0.09 13.0 0.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain MBOAT_2 PF13813.6 OAG21454.1 - 7.3e-17 61.4 7.5 1.8e-16 60.2 7.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FRG1 PF06229.12 OAG21456.1 - 1.3e-53 181.6 0.5 2.2e-53 180.8 0.5 1.4 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 OAG21456.1 - 9.4e-05 22.6 0.0 0.0075 16.5 0.0 3.0 1 1 2 3 3 3 2 Fascin domain 2OG-FeII_Oxy PF03171.20 OAG21457.1 - 0.00061 20.2 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG21457.1 - 0.00098 19.9 0.1 0.0076 17.0 0.0 2.1 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Acyl_transf_3 PF01757.22 OAG21458.1 - 1.2e-19 70.5 21.3 1.8e-19 70.0 21.3 1.3 1 0 0 1 1 1 1 Acyltransferase family NAD_binding_1 PF00175.21 OAG21460.1 - 2.6e-33 114.9 0.0 3.9e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG21460.1 - 6e-25 87.5 0.0 1.2e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAG21460.1 - 6.7e-08 32.8 0.0 0.0003 21.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG21460.1 - 0.00033 20.8 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF1664 PF07889.12 OAG21461.1 - 0.02 14.9 0.2 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HATPase_c PF02518.26 OAG21462.1 - 6.3e-23 81.4 0.0 1.2e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG21462.1 - 3.3e-21 75.5 0.1 7.6e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAG21462.1 - 2e-07 31.3 0.0 2.8e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 OAG21462.1 - 1.9e-06 27.8 1.0 5.2e-06 26.4 0.0 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG21462.1 - 2e-06 28.0 0.2 4.3e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG21462.1 - 1.1e-05 25.4 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG21462.1 - 1.1e-05 25.6 0.0 0.00075 19.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OAG21462.1 - 1.2e-05 25.2 0.0 3.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 OAG21462.1 - 0.0016 18.7 0.0 0.016 15.5 0.0 2.5 1 1 1 2 2 2 1 GAF domain GntR PF00392.21 OAG21462.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family WW PF00397.26 OAG21465.1 - 3.1e-10 40.0 5.3 6.5e-10 38.9 5.3 1.6 1 0 0 1 1 1 1 WW domain Chal_sti_synt_N PF00195.19 OAG21466.1 - 5.7e-17 61.9 0.9 5.4e-16 58.7 0.1 2.7 2 1 1 3 3 3 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 OAG21466.1 - 1.2e-16 61.1 0.0 2.1e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain UDG PF03167.19 OAG21466.1 - 5.3e-12 46.0 0.0 1.6e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily ACP_syn_III_C PF08541.10 OAG21466.1 - 0.00019 21.5 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 OAG21466.1 - 0.0014 18.0 0.0 0.013 14.8 0.0 2.3 2 1 1 3 3 3 1 FAE1/Type III polyketide synthase-like protein Glyco_hydro_79C PF16862.5 OAG21468.1 - 1e-19 71.3 0.1 2.4e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DnaJ PF00226.31 OAG21469.1 - 1.3e-08 34.8 0.1 3.2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain FliT PF05400.13 OAG21469.1 - 0.21 12.4 1.6 0.37 11.6 1.6 1.3 1 0 0 1 1 1 0 Flagellar protein FliT Sugar_tr PF00083.24 OAG21470.1 - 6.8e-110 368.0 20.9 7.9e-110 367.8 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21470.1 - 5.4e-26 91.4 26.3 4.8e-20 71.8 3.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TPR_2 PF07719.17 OAG21471.1 - 8.3e-10 38.0 3.6 1.9e-05 24.4 0.0 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG21471.1 - 4.3e-09 35.8 0.7 5.5e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 OAG21471.1 - 1.2e-08 34.6 0.1 3.9e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.6 OAG21471.1 - 1.3e-06 28.1 1.5 0.0062 16.7 0.1 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat F-box-like PF12937.7 OAG21471.1 - 1.5e-06 28.0 0.1 3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 OAG21471.1 - 3.7e-05 24.0 12.4 0.45 11.0 0.1 6.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) TPR_11 PF13414.6 OAG21471.1 - 0.00071 19.2 0.1 0.0059 16.3 0.1 2.3 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 OAG21471.1 - 0.0017 18.6 0.2 0.014 15.6 0.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG21471.1 - 0.0046 17.5 0.1 0.068 13.8 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG21471.1 - 0.0058 17.3 0.0 1.4 10.0 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG21471.1 - 0.036 14.2 0.0 1.7 8.9 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OAG21471.1 - 0.051 12.5 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 OAG21471.1 - 0.071 13.4 0.2 3.1 8.1 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OAG21471.1 - 0.091 12.7 0.2 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 OAG21471.1 - 0.25 11.2 4.8 4.5 7.1 0.1 4.8 5 1 0 5 5 4 0 Leucine rich repeat TPR_3 PF07720.12 OAG21471.1 - 0.45 10.6 1.8 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 OAG21471.1 - 0.59 10.3 0.0 0.59 10.3 0.0 3.2 4 0 0 4 4 1 0 Leucine Rich repeat Kelch_4 PF13418.6 OAG21472.1 - 8.9e-29 99.3 6.6 7.3e-08 32.3 0.0 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG21472.1 - 8.3e-26 89.4 7.0 1.1e-07 31.8 0.5 5.3 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OAG21472.1 - 9.7e-25 86.1 5.3 3e-06 27.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OAG21472.1 - 1.5e-21 75.7 3.8 2.9e-06 26.7 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OAG21472.1 - 8.1e-19 67.5 16.3 1.2e-06 28.7 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG21472.1 - 3.6e-17 61.6 3.8 6.3e-05 22.8 0.2 5.0 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 OAG21472.1 - 1.5e-08 34.9 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OAG21472.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 OAG21473.1 - 1.3e-16 60.6 3.8 3.7e-05 24.0 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG21473.1 - 3.6e-15 56.1 12.4 0.0019 19.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG21473.1 - 6.4e-07 28.6 0.1 0.00022 20.3 0.0 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG21473.1 - 3.7e-05 23.7 0.2 0.015 15.2 0.3 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Glyco_hyd_101C PF17451.2 OAG21473.1 - 0.021 15.1 0.1 0.96 9.8 0.2 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain SSF PF00474.17 OAG21474.1 - 4.7e-21 75.1 34.4 7.2e-21 74.5 34.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Nucleos_tra2_C PF07662.13 OAG21475.1 - 1.1e-68 231.1 0.1 1.1e-68 231.1 0.1 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAG21475.1 - 1.4e-22 80.1 6.1 1.4e-22 80.1 6.1 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.16 OAG21475.1 - 7.9 6.0 6.6 0.97 8.9 1.5 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Bromodomain PF00439.25 OAG21477.1 - 2e-22 79.1 1.3 3.5e-22 78.3 1.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OAG21477.1 - 1.5e-08 34.9 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG21477.1 - 2.7e-07 30.6 0.3 1e-06 28.7 0.2 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG21477.1 - 0.00017 22.0 0.1 0.00034 21.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG21477.1 - 0.21 11.5 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ost5 PF05251.12 OAG21478.1 - 4.8e-22 78.0 8.7 5.6e-22 77.8 8.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 OAG21479.1 - 2.8e-85 285.7 0.0 3.3e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TFIIA PF03153.13 OAG21480.1 - 2.5e-77 261.6 25.1 4.4e-77 260.8 25.1 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.21 OAG21481.1 - 0.00066 19.7 5.2 0.0015 18.6 4.9 1.8 1 1 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 OAG21481.1 - 0.072 12.9 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Synaptonemal_3 PF15191.6 OAG21481.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 PAF-AH_p_II PF03403.13 OAG21482.1 - 2.7e-51 174.3 0.0 2.9e-27 95.2 0.0 3.0 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG21482.1 - 6.9e-07 28.4 0.0 7.5e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG21482.1 - 0.00021 20.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG21482.1 - 0.0029 16.7 0.0 0.0097 15.0 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase Metallophos PF00149.28 OAG21483.1 - 3.7e-14 53.7 0.1 5.2e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_G PF04718.15 OAG21484.1 - 0.028 15.2 0.4 0.09 13.6 0.0 2.0 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit DUF4192 PF13830.6 OAG21484.1 - 0.072 13.1 0.2 0.089 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Thg1 PF04446.12 OAG21485.1 - 7.4e-51 171.4 0.0 1.2e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAG21485.1 - 7.4e-48 161.7 0.1 7.2e-43 145.6 0.0 2.4 2 0 0 2 2 2 2 Thg1 C terminal domain Response_reg PF00072.24 OAG21486.1 - 1.3e-24 86.6 2.9 1.9e-24 86.0 0.8 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 OAG21486.1 - 4.5e-21 75.5 0.1 1.4e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 OAG21486.1 - 2.8e-09 37.2 0.2 5.3e-08 33.1 0.1 2.8 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 OAG21486.1 - 3.7e-09 36.5 0.0 1.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 OAG21486.1 - 5.9e-09 35.9 0.0 1.9e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 PAS fold DUF1828 PF08861.10 OAG21486.1 - 0.0014 18.9 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF1828 GAF_2 PF13185.6 OAG21486.1 - 0.0067 16.7 0.0 0.023 15.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain LpxC PF03331.13 OAG21486.1 - 0.0091 15.5 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase PAS_8 PF13188.7 OAG21486.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 OAG21486.1 - 0.017 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain HisKA_4TM PF16926.5 OAG21486.1 - 0.063 12.8 0.2 2.9 7.4 0.2 2.3 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase PAS_3 PF08447.12 OAG21486.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 PAS fold GAF_3 PF13492.6 OAG21486.1 - 0.075 13.4 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 GAF domain DIT1_PvcA PF05141.12 OAG21487.1 - 3e-82 276.2 0.0 3.5e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Epimerase PF01370.21 OAG21489.1 - 1.8e-09 37.4 0.0 2.6e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG21489.1 - 2.8e-05 24.1 0.0 0.00053 19.9 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG21489.1 - 0.00022 20.9 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAG21489.1 - 0.0004 19.6 0.0 0.0021 17.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 OAG21489.1 - 0.0094 15.1 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 OAG21489.1 - 0.035 14.5 0.0 0.2 12.1 0.0 2.1 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG21489.1 - 0.057 12.4 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1381 PF07129.11 OAG21489.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) zf-MYND PF01753.18 OAG21490.1 - 5.8e-10 39.1 15.1 8.8e-10 38.5 15.1 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 OAG21490.1 - 0.009 15.9 9.5 0.014 15.2 9.5 1.3 1 0 0 1 1 1 1 HIT zinc finger Ecl1 PF12855.7 OAG21490.1 - 0.048 14.8 2.6 0.08 14.1 2.6 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins SPRY PF00622.28 OAG21491.1 - 0.00016 21.8 0.0 0.0009 19.4 0.0 2.2 2 1 0 2 2 2 1 SPRY domain AtuA PF07287.11 OAG21492.1 - 4.9e-123 410.3 0.1 5.8e-123 410.1 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Zeta_toxin PF06414.12 OAG21492.1 - 0.05 12.9 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NAD_binding_3 PF03447.16 OAG21492.1 - 0.1 13.2 0.0 0.92 10.2 0.0 2.5 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain CoA_transf_3 PF02515.17 OAG21493.1 - 1.8e-37 129.3 0.0 2e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Acetyltransf_3 PF13302.7 OAG21494.1 - 5.9e-18 65.9 0.0 8.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG21494.1 - 9.5e-05 22.6 0.0 0.0038 17.5 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG21494.1 - 0.086 12.8 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein FAD-oxidase_C PF02913.19 OAG21495.1 - 2e-63 214.3 0.1 3.8e-63 213.4 0.1 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG21495.1 - 7.2e-38 129.5 0.0 2.1e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Duffy_binding PF05424.11 OAG21495.1 - 0.009 16.1 0.5 0.65 10.0 0.6 2.4 2 0 0 2 2 2 1 Duffy binding domain IATP PF04568.12 OAG21496.1 - 0.014 15.8 3.8 0.035 14.5 3.8 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ARGLU PF15346.6 OAG21496.1 - 0.063 13.2 14.9 0.098 12.5 14.9 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Presenilin PF01080.17 OAG21496.1 - 4.3 6.0 4.0 5.4 5.7 4.0 1.2 1 0 0 1 1 1 0 Presenilin Lactamase_B_3 PF13483.6 OAG21498.1 - 4.5e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG21498.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Glyco_hydro_12 PF01670.16 OAG21501.1 - 1.6e-20 74.1 4.4 2e-20 73.7 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Cadherin_5 PF17892.1 OAG21501.1 - 0.061 13.3 0.3 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Cadherin-like domain Transp_cyt_pur PF02133.15 OAG21503.1 - 5.8e-87 292.3 34.4 1e-86 291.5 34.4 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Isochorismatase PF00857.20 OAG21504.1 - 3.4e-31 108.8 0.1 3.9e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family PA_decarbox PF05870.11 OAG21505.1 - 9.5e-10 38.3 0.2 1.2e-09 38.0 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Ada_Zn_binding PF02805.16 OAG21508.1 - 3.8e-28 97.3 4.8 5.7e-28 96.7 4.8 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAG21508.1 - 9.9e-08 31.9 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 OAG21508.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DNA_mis_repair PF01119.19 OAG21509.1 - 2.9e-12 46.3 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG21509.1 - 3.6e-10 39.8 0.0 8.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG21509.1 - 1.8e-06 28.4 0.0 4.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Met_10 PF02475.16 OAG21510.1 - 3e-68 229.5 0.0 4.2e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 OAG21510.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Kinesin PF00225.23 OAG21511.1 - 2.8e-113 378.3 0.0 5.8e-113 377.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 OAG21511.1 - 4.5e-40 137.8 0.0 1.3e-39 136.3 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 OAG21511.1 - 5e-40 137.6 3.5 2.7e-31 109.1 0.6 3.1 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 OAG21511.1 - 4.7e-24 85.0 0.5 3.6e-23 82.2 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 OAG21511.1 - 3.8e-05 24.2 0.0 0.00014 22.3 0.0 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 OAG21511.1 - 9e-05 22.8 2.6 0.00043 20.6 2.6 2.3 1 0 0 1 1 1 1 Kinesin protein 1B PH_11 PF15413.6 OAG21511.1 - 0.016 15.6 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain UPF0242 PF06785.11 OAG21511.1 - 0.21 11.7 13.8 0.39 10.8 0.9 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 OAG21511.1 - 0.71 10.3 11.0 0.39 11.2 1.0 3.3 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.6 OAG21511.1 - 5.6 6.2 16.2 0.61 9.4 9.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APH PF01636.23 OAG21512.1 - 6e-38 131.1 0.0 8.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG21512.1 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 OAG21512.1 - 0.011 15.3 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family SLAC1 PF03595.17 OAG21513.1 - 1.3e-75 254.7 43.9 1.5e-75 254.4 43.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TFIIA PF03153.13 OAG21513.1 - 5.5 6.9 20.0 8.9 6.2 20.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.28 OAG21514.1 - 4.5e-10 39.7 0.1 1.6e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain Helicase_C PF00271.31 OAG21515.1 - 5.7e-32 110.3 0.2 5.8e-31 107.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG21515.1 - 6.1e-23 81.5 0.1 1.2e-22 80.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 OAG21515.1 - 0.0062 15.9 0.2 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit fragilysinNterm PF16376.5 OAG21515.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin AAA_22 PF13401.6 OAG21515.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 OAG21516.1 - 3.5e-12 46.6 0.0 4.4e-09 36.4 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 OAG21516.1 - 1.5e-09 38.2 0.0 4.7e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 OAG21516.1 - 1.2e-06 28.3 0.3 2.5e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG21516.1 - 5.4e-05 22.9 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 OAG21516.1 - 0.017 15.6 0.1 0.045 14.3 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RabGAP-TBC PF00566.18 OAG21517.1 - 9.3e-35 120.2 0.0 1.5e-27 96.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Cu-oxidase_2 PF07731.14 OAG21518.1 - 7.8e-27 93.7 1.5 2.4e-24 85.6 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG21518.1 - 1.4e-20 73.5 0.2 4.8e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG21518.1 - 8.6e-05 22.7 0.0 0.00025 21.2 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Macoilin PF09726.9 OAG21518.1 - 0.06 11.9 3.6 0.076 11.6 3.6 1.1 1 0 0 1 1 1 0 Macoilin family Bromodomain PF00439.25 OAG21522.1 - 4.8e-37 125.9 1.0 1.9e-19 69.5 0.2 2.4 2 0 0 2 2 2 2 Bromodomain Pkinase PF00069.25 OAG21523.1 - 2.8e-70 236.7 0.0 3.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21523.1 - 4.9e-38 130.9 0.0 6.8e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG21523.1 - 2.4e-06 27.1 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG21523.1 - 0.00097 18.0 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OAG21523.1 - 0.0015 18.1 0.1 0.0061 16.1 0.1 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 OAG21523.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 OAG21523.1 - 0.032 14.3 0.0 0.084 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4199 PF13858.6 OAG21524.1 - 5.7e-05 23.6 0.3 6.3e-05 23.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) YajC PF02699.15 OAG21524.1 - 0.009 15.9 0.1 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Preprotein translocase subunit Tom5 PF10642.9 OAG21524.1 - 0.094 12.8 0.7 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase ABC_membrane PF00664.23 OAG21524.1 - 0.17 11.5 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2127 PF09900.9 OAG21524.1 - 0.17 12.1 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF1294 PF06961.13 OAG21525.1 - 2.6e-23 82.0 0.3 4.2e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) DUF4336 PF14234.6 OAG21526.1 - 0.028 13.6 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) PALP PF00291.25 OAG21528.1 - 1.8e-62 211.4 0.0 2.1e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 OAG21529.1 - 6.1e-36 124.4 0.0 8.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HpcH_HpaI PF03328.14 OAG21530.1 - 3.4e-46 157.2 0.0 4.6e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAG21530.1 - 4.5e-14 52.3 0.0 5e-07 29.2 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 OAG21531.1 - 8.6e-45 152.2 12.1 1e-43 148.7 7.5 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF846) 2-Hacid_dh_C PF02826.19 OAG21532.1 - 1e-43 148.8 0.1 4.1e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG21532.1 - 0.00044 19.9 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 OAG21532.1 - 0.0086 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 OAG21532.1 - 0.019 14.5 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 OAG21532.1 - 0.02 15.1 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 OAG21532.1 - 0.035 14.6 0.0 0.072 13.6 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 OAG21532.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 OAG21532.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 7tm_2 PF00002.24 OAG21533.1 - 1.2e-07 31.3 12.5 1.2e-07 31.2 11.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) ANAPC_CDC26 PF10471.9 OAG21534.1 - 9.8e-14 51.9 4.0 1.1e-13 51.8 4.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Glycolytic PF00274.19 OAG21534.1 - 0.031 13.0 0.9 0.035 12.8 0.9 1.0 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Androgen_recep PF02166.16 OAG21534.1 - 0.052 12.4 1.5 0.053 12.4 1.5 1.0 1 0 0 1 1 1 0 Androgen receptor Exonuc_X-T_C PF08411.10 OAG21534.1 - 0.11 11.6 0.4 0.12 11.5 0.4 1.0 1 0 0 1 1 1 0 Exonuclease C-terminal ThiF PF00899.21 OAG21536.1 - 4.8e-63 212.8 0.0 6.4e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAG21536.1 - 6.6e-28 96.7 0.1 1e-27 96.0 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAG21536.1 - 0.00014 21.9 0.5 0.00042 20.4 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG21536.1 - 0.064 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 OAG21536.1 - 0.093 12.9 1.0 0.2 11.9 1.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 OAG21536.1 - 0.11 12.7 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAG21536.1 - 0.14 12.6 0.0 0.47 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding PglD_N PF17836.1 OAG21536.1 - 0.15 12.7 0.7 0.49 11.1 0.4 2.1 1 1 0 1 1 1 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 OAG21536.1 - 0.19 11.6 2.5 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 OAG21537.1 - 1.8e-36 124.9 1.9 1.2e-35 122.3 0.0 3.2 4 0 0 4 4 4 1 Telomere length regulation protein HET PF06985.11 OAG21540.1 - 7e-19 68.6 0.1 1.6e-18 67.5 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_16 PF00722.21 OAG21541.1 - 1.9e-07 30.7 0.5 3.8e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 L27 PF02828.16 OAG21541.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 L27 domain Thiolase_N PF00108.23 OAG21542.1 - 4.7e-93 311.3 0.1 8.4e-93 310.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG21542.1 - 3.2e-42 143.0 3.7 3e-41 139.9 2.3 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG21542.1 - 1.2e-06 28.3 2.4 0.0003 20.5 1.1 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG21542.1 - 0.0026 17.6 5.0 0.016 15.0 0.1 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 OAG21543.1 - 4.1e-46 157.0 0.0 5.9e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAG21543.1 - 6.8e-36 123.5 6.8 1.4e-35 122.6 6.8 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAG21543.1 - 8.8e-21 73.9 0.0 4e-20 71.8 0.0 2.1 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG21543.1 - 1.4e-17 63.5 0.0 3.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG21543.1 - 8.5e-09 35.7 0.1 2.4e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG21543.1 - 1.1e-06 28.6 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAG21543.1 - 0.00017 21.6 0.1 0.00043 20.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG21543.1 - 0.042 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras family DUF5505 PF17610.2 OAG21543.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5505) RTC4 PF14474.6 OAG21544.1 - 2.1e-28 98.9 1.2 2.8e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain RTC_insert PF05189.13 OAG21545.1 - 1.7e-30 105.6 0.0 5.1e-30 104.0 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 OAG21545.1 - 1.7e-28 99.3 0.1 2.2e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Peptidase_S8 PF00082.22 OAG21546.1 - 2.9e-37 128.6 2.7 5.3e-37 127.7 2.7 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OAG21546.1 - 3.3e-28 97.5 0.2 6.5e-28 96.6 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAG21546.1 - 0.00027 21.6 0.3 0.00064 20.4 0.3 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain Mucin PF01456.17 OAG21546.1 - 0.0046 16.9 2.8 0.0091 16.0 2.8 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1180 PF06679.12 OAG21546.1 - 0.0054 17.2 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) PhoD PF09423.10 OAG21547.1 - 3.2e-08 33.0 0.2 2.3e-07 30.2 0.2 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S9 PF00326.21 OAG21548.1 - 4.6e-53 179.8 0.1 7.5e-53 179.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG21548.1 - 0.0097 15.8 4.0 0.5 10.4 0.5 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat GNAT_acetyltr_2 PF13718.6 OAG21549.1 - 4e-100 333.9 0.0 9.3e-100 332.7 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAG21549.1 - 8e-91 303.9 0.1 1.8e-90 302.8 0.1 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OAG21549.1 - 7.1e-65 218.2 0.0 2.4e-64 216.5 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 OAG21549.1 - 4.6e-34 116.2 0.2 1.2e-33 114.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 OAG21549.1 - 9.1e-05 22.3 0.2 0.017 14.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAG21549.1 - 0.00025 21.3 0.5 0.0067 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain INSC_LBD PF16748.5 OAG21549.1 - 0.042 13.3 1.5 0.28 10.7 0.1 2.9 3 0 0 3 3 3 0 Inscuteable LGN-binding domain AAA_19 PF13245.6 OAG21549.1 - 0.046 14.0 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 OAG21549.1 - 0.063 13.5 0.0 0.47 10.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family GHMP_kinases_N PF00288.26 OAG21549.1 - 0.15 12.3 0.2 0.38 11.0 0.2 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain CAP_GLY PF01302.25 OAG21550.1 - 1.3e-15 57.2 1.2 2.3e-15 56.4 1.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 OAG21550.1 - 9.4e-07 28.6 11.0 6.1e-05 22.8 3.1 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle NPV_P10 PF05531.12 OAG21550.1 - 6.5e-05 23.3 7.6 0.17 12.3 0.3 3.4 4 0 0 4 4 3 2 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 OAG21550.1 - 0.0031 15.7 6.0 0.0031 15.7 6.0 2.7 3 0 0 3 3 3 1 Septation ring formation regulator, EzrA Paramyx_P_V_C PF03210.13 OAG21550.1 - 0.0052 16.6 0.2 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal PI3K_P85_iSH2 PF16454.5 OAG21550.1 - 0.02 14.5 19.2 0.29 10.7 2.5 3.4 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4618 PF15397.6 OAG21550.1 - 0.042 13.3 16.7 0.49 9.8 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) ATG16 PF08614.11 OAG21550.1 - 0.062 13.5 41.2 0.19 11.9 6.8 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OAG21550.1 - 0.068 13.6 30.9 0.11 12.9 10.6 3.3 3 0 0 3 3 3 0 Fez1 Fib_alpha PF08702.10 OAG21550.1 - 0.2 11.9 11.0 9.5 6.4 1.1 4.0 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 OAG21550.1 - 0.49 10.4 9.0 1.1 9.3 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAG21550.1 - 0.62 8.9 39.7 0.56 9.0 11.7 3.3 1 1 2 4 4 4 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OAG21550.1 - 1.5 8.9 5.3 10 6.1 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.14 OAG21550.1 - 1.7 7.8 19.0 0.64 9.3 2.2 3.2 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 OAG21550.1 - 2.5 7.4 27.3 2.6 7.3 3.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 OAG21550.1 - 3.1 6.6 31.1 0.044 12.7 17.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DHR10 PF18595.1 OAG21550.1 - 3.1 7.9 40.9 0.75 9.9 12.5 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain E2R135 PF11570.8 OAG21550.1 - 3.3 8.0 6.7 5.2 7.4 0.1 3.4 2 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 BST2 PF16716.5 OAG21550.1 - 4.9 7.8 25.0 2.9 8.6 1.4 4.0 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Occludin_ELL PF07303.13 OAG21550.1 - 6 7.6 11.3 1.3 9.8 0.6 3.3 3 0 0 3 3 3 0 Occludin homology domain FlxA PF14282.6 OAG21550.1 - 8.3 6.5 15.3 3.2 7.8 3.7 3.4 3 0 0 3 3 3 0 FlxA-like protein APH PF01636.23 OAG21551.1 - 4.4e-39 134.8 0.0 6.6e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG21551.1 - 8.3e-06 25.3 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAG21551.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG21551.1 - 0.017 14.8 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OAG21551.1 - 0.022 14.1 0.1 0.35 10.2 0.0 2.7 3 1 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DuffyBP_N PF12377.8 OAG21551.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.7 2 0 0 2 2 2 0 Duffy binding protein N terminal LSM PF01423.22 OAG21552.1 - 2e-19 69.0 0.4 2.2e-19 68.9 0.4 1.1 1 0 0 1 1 1 1 LSM domain Cas_NE0113 PF09623.10 OAG21552.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) RasGAP_C PF03836.15 OAG21553.1 - 0.0021 18.2 0.2 0.0056 16.8 0.2 1.7 1 0 0 1 1 1 1 RasGAP C-terminus UPF0242 PF06785.11 OAG21553.1 - 0.025 14.7 2.6 0.025 14.7 2.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 OAG21553.1 - 0.03 13.9 1.7 0.055 13.1 0.4 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Cmc1 PF08583.10 OAG21554.1 - 6.1e-17 61.4 3.7 7.1e-17 61.2 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF728 PF05304.12 OAG21554.1 - 0.0039 17.0 1.3 0.0044 16.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF728) Arm-DNA-bind_2 PF12167.8 OAG21554.1 - 0.041 13.8 0.5 0.06 13.3 0.5 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain Prefoldin_2 PF01920.20 OAG21555.1 - 2.3e-23 82.2 9.1 3.2e-23 81.7 9.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit UvrD_C PF13361.6 OAG21555.1 - 0.0084 15.5 3.5 0.0092 15.4 3.5 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SAS-6_N PF16531.5 OAG21555.1 - 0.02 15.5 0.3 0.034 14.7 0.3 1.6 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal Prefoldin PF02996.17 OAG21555.1 - 0.039 13.9 10.1 1.7 8.6 10.1 2.2 1 1 0 1 1 1 0 Prefoldin subunit Troponin PF00992.20 OAG21555.1 - 0.073 13.4 6.2 0.65 10.3 0.3 2.1 2 0 0 2 2 2 0 Troponin DUF2089 PF09862.9 OAG21555.1 - 0.076 13.0 2.3 0.79 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) SLATT_1 PF18181.1 OAG21555.1 - 0.21 11.5 4.3 0.21 11.5 1.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 APG6_N PF17675.1 OAG21555.1 - 0.31 11.6 8.1 1.8 9.1 0.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Com_YlbF PF06133.11 OAG21555.1 - 0.49 11.0 10.0 0.5 11.0 1.2 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA WXG100 PF06013.12 OAG21555.1 - 1.2 9.4 6.8 1.1 9.6 2.2 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG bZIP_Maf PF03131.17 OAG21555.1 - 6.5 7.3 9.3 11 6.6 0.3 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor CBFD_NFYB_HMF PF00808.23 OAG21556.1 - 1.2e-29 102.4 1.2 1.6e-29 101.9 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG21556.1 - 2.3e-06 28.0 0.1 3.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OAG21556.1 - 0.00029 20.8 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 OAG21556.1 - 0.00066 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 OAG21556.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 OAG21556.1 - 0.02 15.4 0.2 0.061 13.8 0.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Fanconi_A_N PF15865.5 OAG21556.1 - 0.098 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus PAN_2 PF08276.11 OAG21556.1 - 0.37 10.9 0.3 0.37 10.9 0.3 1.9 2 1 0 2 2 2 0 PAN-like domain DHHC PF01529.20 OAG21557.1 - 7e-34 116.8 3.3 1.3e-33 116.0 3.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 OAG21557.1 - 1.5 8.7 4.9 0.27 11.1 0.3 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily Glyco_transf_22 PF03901.17 OAG21558.1 - 7.8e-28 97.8 11.0 9.6e-28 97.5 11.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SUI1 PF01253.22 OAG21559.1 - 1.5e-26 92.7 0.1 1.5e-26 92.7 0.1 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 R3H-assoc PF13902.6 OAG21559.1 - 0.034 14.5 0.7 0.055 13.9 0.7 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain Sec63 PF02889.16 OAG21560.1 - 5.7e-165 546.7 0.1 7.8e-89 297.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAG21560.1 - 2.6e-46 157.6 0.4 1.4e-26 93.3 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAG21560.1 - 2e-31 108.4 3.4 2e-31 108.4 3.4 2.6 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 OAG21560.1 - 6.8e-23 81.5 0.0 1.2e-12 48.2 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG21560.1 - 1.1e-10 41.8 0.0 3.1e-08 33.9 0.0 3.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG21560.1 - 7.1e-05 22.6 0.0 0.031 14.0 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 OAG21560.1 - 0.00017 21.9 0.5 0.71 10.1 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG21560.1 - 0.0074 16.6 1.1 1.9 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.21 OAG21560.1 - 0.0075 15.8 3.5 3.3 7.1 0.0 3.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 OAG21560.1 - 0.047 13.1 0.0 3.5 7.0 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein TFIIE_alpha PF02002.17 OAG21560.1 - 0.057 13.3 0.8 21 5.0 0.0 3.7 3 0 0 3 3 3 0 TFIIE alpha subunit Abhydrolase_4 PF08386.10 OAG21561.1 - 2.1e-22 79.2 0.0 4.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAG21561.1 - 2.7e-18 66.6 0.1 1.7e-05 24.6 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold RRM_1 PF00076.22 OAG21562.1 - 1.1e-20 73.2 0.0 1.2e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAG21562.1 - 0.052 13.6 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain HofP PF10748.9 OAG21562.1 - 0.098 12.2 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 DNA utilization proteins HofP Limkain-b1 PF11608.8 OAG21562.1 - 0.12 12.4 0.3 0.13 12.3 0.3 1.3 1 1 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 OAG21562.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Pyrophosphatase PF00719.19 OAG21564.1 - 2.6e-59 199.6 0.2 3.4e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 OAG21565.1 - 2.9e-23 81.8 0.2 4.5e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 OAG21566.1 - 1.3e-13 50.6 1.5 1.3e-13 50.6 1.5 2.0 3 0 0 3 3 3 1 Sec20 ArAE_2 PF10334.9 OAG21566.1 - 0.041 13.7 0.2 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 DUF948 PF06103.11 OAG21566.1 - 0.087 13.1 3.2 1.1 9.6 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FR47 PF08445.10 OAG21568.1 - 4.4e-08 33.0 0.0 1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 OAG21568.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Ribosomal_L10 PF00466.20 OAG21569.1 - 3.1e-25 88.2 0.1 7.2e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OAG21569.1 - 8e-22 77.0 0.1 1.9e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OAG21569.1 - 3.3e-21 75.7 3.8 3.3e-21 75.7 3.8 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.32 OAG21570.1 - 4e-07 30.6 0.5 0.0021 18.8 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.15 OAG21570.1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region CSRNP_N PF16019.5 OAG21571.1 - 0.015 15.2 1.5 0.021 14.8 1.5 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CpcD PF01383.21 OAG21571.1 - 0.097 13.0 0.1 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain Pyr_redox_2 PF07992.14 OAG21572.1 - 8.6e-43 146.6 0.8 1.1e-42 146.3 0.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG21572.1 - 9.2e-18 64.5 0.1 2.8e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG21572.1 - 8.8e-15 55.0 0.1 2.5e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG21572.1 - 2.1e-05 23.8 0.2 0.013 14.6 0.0 2.6 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG21572.1 - 0.0024 17.5 0.0 2.5 7.6 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG21572.1 - 0.0065 15.7 0.0 3.3 6.9 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 OAG21572.1 - 0.036 13.2 5.0 1.9 7.5 0.1 3.6 3 2 1 4 4 4 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAG21572.1 - 0.044 14.2 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 OAG21572.1 - 0.053 12.9 4.1 0.12 11.7 0.1 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.16 OAG21572.1 - 0.056 13.1 0.1 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 OAG21572.1 - 0.14 12.6 0.0 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Atg14 PF10186.9 OAG21573.1 - 3.8e-84 282.5 0.6 4.9e-84 282.1 0.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ArnB_C PF18677.1 OAG21573.1 - 0.052 13.7 1.7 0.13 12.4 1.7 1.7 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Remorin_C PF03763.13 OAG21573.1 - 1.8 8.4 12.8 3.2 7.7 5.5 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region TMPIT PF07851.13 OAG21573.1 - 1.9 7.7 5.7 2.8 7.1 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cys_Met_Meta_PP PF01053.20 OAG21574.1 - 5.5e-142 472.8 0.0 6.2e-142 472.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG21574.1 - 6.1e-10 38.8 0.1 9.7e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG21574.1 - 1.8e-06 27.5 0.1 2.8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG21574.1 - 3.2e-06 26.4 0.1 5.4e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Crinivirus_P26 PF07416.11 OAG21574.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Crinivirus P26 protein Mucin PF01456.17 OAG21575.1 - 1.4e-05 25.2 16.3 1.5e-05 25.0 16.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Sec10 PF07393.11 OAG21575.1 - 0.034 12.6 0.8 0.043 12.2 0.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 MGC-24 PF05283.11 OAG21575.1 - 0.19 12.1 10.2 0.28 11.6 10.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SprA-related PF12118.8 OAG21575.1 - 1.1 8.3 10.6 1.4 7.9 10.6 1.1 1 0 0 1 1 1 0 SprA-related family Dicty_REP PF05086.12 OAG21575.1 - 1.3 6.9 4.7 1.6 6.7 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 OAG21575.1 - 1.7 6.7 12.8 2 6.5 12.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2457 PF10446.9 OAG21575.1 - 4.3 6.4 6.2 5.5 6.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mito_carr PF00153.27 OAG21578.1 - 2.2e-63 210.2 2.6 9e-21 73.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG21578.1 - 0.24 10.5 2.0 1.1 8.4 0.1 2.9 3 1 0 3 3 3 0 Gammaproteobacterial serine protease TauD PF02668.16 OAG21579.1 - 1.7e-47 162.5 2.6 1.9e-47 162.4 1.8 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG21579.1 - 0.00061 20.4 0.5 0.0022 18.6 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF971) zf-B_box PF00643.24 OAG21581.1 - 0.0037 17.4 2.8 0.0058 16.8 2.8 1.2 1 0 0 1 1 1 1 B-box zinc finger Thioredoxin_4 PF13462.6 OAG21582.1 - 6.5e-10 39.4 0.0 2.1e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OAG21582.1 - 0.028 14.2 1.8 1.7 8.3 0.1 2.8 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Sin3a_C PF16879.5 OAG21583.1 - 1.6e-67 228.2 13.7 1.6e-67 228.2 13.7 3.0 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAG21583.1 - 8.6e-44 147.4 1.4 1.8e-17 63.2 0.5 4.2 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAG21583.1 - 1.1e-39 134.5 0.1 4.2e-39 132.6 0.1 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor Glyco_hydro_3_C PF01915.22 OAG21584.1 - 7e-65 218.8 0.0 1.7e-64 217.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG21584.1 - 8.2e-53 179.8 0.0 1.4e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 OAG21584.1 - 3.9e-21 75.4 0.0 6.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 OAG21584.1 - 9.8e-21 73.7 0.1 2.4e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Myosin_head PF00063.21 OAG21585.1 - 8.2e-242 804.2 3.6 1e-241 803.9 3.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 OAG21585.1 - 2.1e-62 210.9 0.0 3.8e-62 210.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Myosin_TH1 PF06017.13 OAG21585.1 - 3.6e-51 173.5 0.0 6.6e-51 172.7 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Pkinase_Tyr PF07714.17 OAG21585.1 - 5.1e-43 147.2 0.0 8.5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 OAG21585.1 - 1.5e-12 46.9 0.1 3.7e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG21585.1 - 3e-10 39.8 0.0 8e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG21585.1 - 1.8e-08 33.9 0.0 4.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain POLO_box PF00659.18 OAG21585.1 - 6.6e-07 29.4 0.7 0.00061 19.9 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OAG21585.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IQ PF00612.27 OAG21585.1 - 0.0023 17.6 3.5 2.6 8.1 0.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 OAG21585.1 - 0.022 15.0 0.0 0.091 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG21585.1 - 0.085 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 OAG21585.1 - 0.1 12.1 0.5 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Kdo PF06293.14 OAG21585.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG21585.1 - 0.14 10.9 1.2 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase OPA3 PF07047.12 OAG21586.1 - 1.3e-44 150.9 4.9 2.1e-44 150.3 4.9 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) NicO PF03824.16 OAG21586.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein She9_MDM33 PF05546.11 OAG21586.1 - 0.021 14.6 1.8 0.035 13.9 1.8 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family DUF1003 PF06210.11 OAG21586.1 - 0.23 11.6 2.2 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Halo_GVPC PF05465.13 OAG21586.1 - 0.25 11.6 2.0 0.62 10.4 2.0 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat APG6_N PF17675.1 OAG21586.1 - 1.2 9.7 9.2 0.41 11.2 1.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3712 PF12505.8 OAG21588.1 - 1.5e-35 122.2 1.3 2.8e-34 118.1 0.4 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAG21588.1 - 0.0091 16.5 0.1 0.32 11.5 0.1 2.4 2 0 0 2 2 2 1 Late embryogenesis abundant protein DUF4187 PF13821.6 OAG21589.1 - 2.7e-21 75.1 0.6 7.2e-21 73.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 OAG21589.1 - 1.7e-12 47.0 0.1 3.1e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG21589.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.5 2 1 1 3 3 3 0 G-patch domain ORC3_N PF07034.11 OAG21590.1 - 4.1e-35 121.4 0.0 8.5e-34 117.1 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 OAG21590.1 - 1.2e-27 96.6 0.0 7.4e-16 58.5 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal 3-HAO PF06052.12 OAG21591.1 - 1.8e-61 206.2 0.0 2.2e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OAG21591.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG21591.1 - 6.1e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG21591.1 - 0.0022 17.6 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Cupin DZR PF12773.7 OAG21591.1 - 0.008 16.2 5.6 0.015 15.3 5.6 1.5 1 0 0 1 1 1 1 Double zinc ribbon ARD PF03079.14 OAG21591.1 - 0.019 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 OAG21591.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Zn-ribbon_8 PF09723.10 OAG21591.1 - 2.7 8.2 5.9 1.3 9.2 0.6 2.2 1 1 1 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 OAG21591.1 - 6.1 6.9 6.5 46 4.1 5.1 2.5 1 1 1 2 2 2 0 Adenylate kinase, active site lid Ctr PF04145.15 OAG21592.1 - 8.7e-30 104.3 13.5 3.3e-28 99.2 13.5 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.20 OAG21592.1 - 0.0036 16.9 0.5 0.0043 16.7 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4191 PF13829.6 OAG21592.1 - 0.34 10.2 1.9 0.6 9.4 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FAD_binding_2 PF00890.24 OAG21593.1 - 2.7e-80 270.5 0.5 3.5e-80 270.1 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAG21593.1 - 7.4e-20 70.9 1.0 1.4e-18 66.8 0.0 3.2 5 0 0 5 5 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OAG21593.1 - 2.6e-11 43.7 0.4 8.8e-11 42.0 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG21593.1 - 3.3e-09 36.6 0.6 1.3e-08 34.6 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG21593.1 - 1.1e-07 31.9 0.6 7.4e-07 29.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG21593.1 - 4.1e-07 29.5 0.1 1.7e-06 27.5 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG21593.1 - 1e-06 28.3 0.1 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG21593.1 - 1.4e-06 27.3 2.5 0.0027 16.5 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 OAG21593.1 - 8.9e-05 21.7 0.8 0.012 14.7 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAG21593.1 - 0.00013 21.3 0.4 0.024 13.9 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OAG21593.1 - 0.0024 17.2 1.2 0.0054 16.0 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 OAG21593.1 - 0.0049 16.2 0.2 1.5 8.1 0.1 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG21593.1 - 0.016 14.5 0.3 0.032 13.5 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IF2_N PF04760.15 OAG21593.1 - 0.029 14.2 0.2 0.072 12.9 0.2 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region 3HCDH_N PF02737.18 OAG21593.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAG21593.1 - 0.12 12.3 0.5 3.2 7.7 0.5 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG21593.1 - 0.19 12.3 1.9 5.1 7.7 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 OAG21594.1 - 2.1e-07 31.6 5.5 7.9e-07 29.8 5.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.6 OAG21594.1 - 0.0042 17.4 0.9 0.012 15.9 0.9 1.8 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA-synt_2c PF01411.19 OAG21595.1 - 2.3e-217 722.9 0.0 3.4e-217 722.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAG21595.1 - 6.5e-17 61.4 0.4 1.7e-16 60.0 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAG21595.1 - 4.9e-09 36.7 0.5 4.9e-09 36.7 0.5 2.7 3 0 0 3 3 3 1 DHHA1 domain Dehydratase_SU PF02287.15 OAG21595.1 - 0.032 14.3 1.4 2.8 8.0 0.6 3.0 3 0 0 3 3 3 0 Dehydratase small subunit RCR PF12273.8 OAG21597.1 - 6.3e-06 26.8 16.7 2.1e-05 25.2 16.7 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-HC5HC2H_2 PF13832.6 OAG21598.1 - 3.1e-18 65.9 1.9 3.1e-18 65.9 1.9 4.2 3 1 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 OAG21598.1 - 1.6e-16 60.3 0.2 3.8e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 OAG21598.1 - 2.8e-12 46.7 3.0 2.8e-12 46.7 3.0 4.7 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 OAG21598.1 - 3.4e-10 39.7 53.4 4.9e-06 26.3 8.2 6.1 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 OAG21598.1 - 1.3e-07 31.0 4.4 1.3e-07 31.0 4.4 4.9 5 0 0 5 5 5 1 PHD-finger C1_2 PF03107.16 OAG21598.1 - 0.022 15.0 0.3 0.022 15.0 0.3 6.3 6 0 0 6 6 6 0 C1 domain Helicase_C PF00271.31 OAG21600.1 - 3e-21 75.9 0.2 9.5e-21 74.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG21600.1 - 4.3e-21 75.7 0.0 9.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG21600.1 - 5.7e-17 62.0 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAG21600.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 OAG21600.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Rhodanese PF00581.20 OAG21601.1 - 9.3e-06 26.1 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain ERO1 PF04137.15 OAG21602.1 - 8.7e-135 449.5 0.0 1.1e-134 449.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Tyrosinase PF00264.20 OAG21603.1 - 5.9e-50 170.6 0.2 8.3e-50 170.1 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1100 PF06500.11 OAG21603.1 - 0.043 12.6 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3487 PF11990.8 OAG21604.1 - 0.05 13.5 0.2 0.05 13.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) LRR19-TM PF15176.6 OAG21606.1 - 0.01 15.8 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain 2OG-FeII_Oxy_3 PF13640.6 OAG21608.1 - 1.2e-07 32.5 0.0 1.9e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ORC6 PF05460.13 OAG21609.1 - 0.0018 17.7 6.9 0.0021 17.4 6.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Dermcidin PF15291.6 OAG21609.1 - 0.2 12.2 4.7 0.4 11.2 4.7 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide F_actin_cap_B PF01115.17 OAG21610.1 - 7.5e-106 353.1 0.0 9e-106 352.8 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RNase_PH_C PF03725.15 OAG21610.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 F-actin_cap_A PF01267.17 OAG21610.1 - 0.14 11.6 0.0 1 8.7 0.0 2.3 1 1 1 2 2 2 0 F-actin capping protein alpha subunit F-box-like PF12937.7 OAG21611.1 - 0.0017 18.2 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like HEM4 PF02602.15 OAG21611.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD adh_short_C2 PF13561.6 OAG21612.1 - 4.4e-21 75.5 0.2 5.9e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG21612.1 - 3e-14 52.9 0.3 3.6e-14 52.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG21612.1 - 0.0013 18.7 0.1 0.004 17.1 0.1 1.7 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.18 OAG21613.1 - 1.3e-20 73.5 1.3 1.9e-20 73.0 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG21614.1 - 3.9e-40 137.9 61.0 3.9e-40 137.9 61.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG21614.1 - 9.3e-17 60.7 27.3 1.3e-16 60.2 27.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG21614.1 - 5.5e-11 42.0 16.4 5.5e-11 42.0 16.4 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Rax2 PF12768.7 OAG21615.1 - 9.8e-65 218.0 0.0 6.1e-64 215.4 0.0 2.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Kelch_2 PF07646.15 OAG21615.1 - 0.039 13.9 2.1 23 5.1 0.1 4.6 5 0 0 5 5 5 0 Kelch motif Smim3 PF17307.2 OAG21615.1 - 0.7 9.4 3.1 1.4 8.5 3.1 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 COesterase PF00135.28 OAG21616.1 - 2e-61 208.4 0.0 2.9e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG21616.1 - 2.6e-06 27.4 0.5 1.7e-05 24.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold PipA PF07108.11 OAG21616.1 - 0.11 12.0 0.1 6.4 6.2 0.0 2.2 2 0 0 2 2 2 0 PipA protein ADH_N PF08240.12 OAG21617.1 - 1.1e-15 57.4 0.0 2.2e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG21617.1 - 2e-11 44.0 0.3 1e-10 41.7 0.3 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG21617.1 - 0.00012 21.6 0.1 0.00022 20.8 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG21617.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAG21618.1 - 7.6e-32 110.4 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21618.1 - 2.1e-22 79.8 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG21618.1 - 0.00011 22.2 0.1 0.00046 20.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG21618.1 - 0.00045 19.7 0.4 0.0013 18.3 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG21618.1 - 0.028 14.5 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ofd1_CTDD PF10637.9 OAG21619.1 - 3.3e-93 311.7 0.0 1e-89 300.3 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAG21619.1 - 3.3e-24 85.3 0.0 9e-24 84.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAG21619.1 - 2.6e-12 47.5 0.0 5.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynamitin PF04912.14 OAG21620.1 - 1e-90 304.9 11.6 1.2e-90 304.7 11.6 1.0 1 0 0 1 1 1 1 Dynamitin Lectin_N PF03954.14 OAG21620.1 - 0.0047 16.7 1.9 0.0047 16.7 1.9 2.0 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain DUF3606 PF12244.8 OAG21620.1 - 0.092 12.7 0.1 0.42 10.6 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3606) SlyX PF04102.12 OAG21620.1 - 0.11 13.1 11.5 0.17 12.5 2.9 4.4 4 1 0 4 4 4 0 SlyX DUF16 PF01519.16 OAG21620.1 - 0.4 11.2 8.6 6 7.4 3.0 3.7 4 0 0 4 4 4 0 Protein of unknown function DUF16 SKA2 PF16740.5 OAG21620.1 - 0.42 10.4 7.0 1.2 9.0 0.0 3.7 4 1 1 5 5 5 0 Spindle and kinetochore-associated protein 2 STAG PF08514.11 OAG21620.1 - 0.85 9.6 3.9 0.32 10.9 0.8 1.9 2 0 0 2 2 2 0 STAG domain DUF2951 PF11166.8 OAG21620.1 - 1.3 9.3 4.7 0.63 10.3 1.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Lebercilin PF15619.6 OAG21620.1 - 9.6 5.8 17.0 0.035 13.8 3.9 3.2 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease P34-Arc PF04045.14 OAG21621.1 - 2.3e-107 358.2 0.5 2.8e-107 357.9 0.5 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 OAG21621.1 - 0.0012 18.4 0.2 0.0094 15.6 0.1 2.1 2 0 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.32 OAG21622.1 - 2.8e-50 167.2 32.4 1.4e-05 25.8 0.2 11.8 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp12 PF04003.12 OAG21622.1 - 3.6e-21 75.5 0.4 7.2e-21 74.5 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAG21622.1 - 2.6e-18 66.1 6.4 0.0022 18.2 0.0 9.2 7 3 3 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG21622.1 - 3.4e-08 32.8 4.0 2.8 6.8 0.0 6.7 4 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG21622.1 - 2e-07 30.0 3.7 0.045 12.4 0.0 6.2 6 1 1 7 7 7 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OAG21622.1 - 1.1e-05 25.3 4.9 24 5.0 0.0 7.8 5 3 3 8 8 8 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 OAG21622.1 - 0.00074 19.4 0.3 0.29 11.0 0.0 4.4 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG21622.1 - 0.0027 17.1 0.0 7.6 5.8 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 OAG21622.1 - 0.0064 15.9 0.2 8.2 5.7 0.0 4.0 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 OAG21622.1 - 0.0069 15.2 3.0 4.9 5.8 0.1 4.5 3 3 1 5 5 5 2 Nup133 N terminal like CDtoxinA PF03498.14 OAG21622.1 - 0.11 12.1 0.0 19 4.8 0.0 2.5 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Utp21 PF04192.12 OAG21622.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Ribosomal_L37 PF08561.10 OAG21623.1 - 1.2e-43 148.4 1.1 1.2e-43 148.4 1.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 Shisa PF13908.6 OAG21623.1 - 0.65 10.2 5.3 1.1 9.4 5.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ndc1_Nup PF09531.10 OAG21623.1 - 5 5.7 6.7 6.4 5.3 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 OAG21625.1 - 5.9e-17 61.7 5.9 0.0067 17.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21625.1 - 5e-07 29.9 0.2 0.015 15.6 0.1 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG21625.1 - 3.4e-05 22.7 2.0 0.0002 20.2 0.2 2.6 2 1 0 3 3 3 1 Nucleoporin Nup120/160 DUF2417 PF10329.9 OAG21626.1 - 3.5e-86 288.5 0.2 5.1e-86 287.9 0.2 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.7 OAG21627.1 - 6e-21 76.1 0.6 6e-21 76.1 0.6 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG21627.1 - 1.5e-05 24.4 0.1 2.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG21627.1 - 0.0042 16.8 0.1 2.7 7.6 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 OAG21627.1 - 0.028 12.9 0.3 1.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.20 OAG21627.1 - 0.031 14.4 0.1 0.15 12.2 0.0 2.1 1 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 OAG21627.1 - 0.058 13.1 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 OAG21627.1 - 0.1 12.4 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 OAG21627.1 - 0.13 11.8 0.1 0.33 10.4 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Sep15_SelM PF08806.11 OAG21627.1 - 0.15 12.2 0.0 2.8 8.2 0.1 2.9 2 2 1 3 3 3 0 Sep15/SelM redox domain Fcf1 PF04900.12 OAG21628.1 - 3.6e-30 104.3 0.3 5.7e-30 103.6 0.3 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAG21628.1 - 0.041 14.2 0.6 0.089 13.1 0.1 1.9 2 1 0 2 2 2 0 PIN like domain Myf5 PF12232.8 OAG21628.1 - 0.049 14.4 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 Myogenic determination factor 5 Presenilin PF01080.17 OAG21628.1 - 5.9 5.5 7.5 8.9 5.0 7.5 1.2 1 0 0 1 1 1 0 Presenilin DUF726 PF05277.12 OAG21629.1 - 4.4e-126 420.4 3.2 6.4e-126 419.9 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pal1 PF08316.11 OAG21630.1 - 2.1e-09 38.3 0.3 7e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 OAG21631.1 - 6.2e-76 255.0 0.1 7.5e-76 254.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein FAD_binding_3 PF01494.19 OAG21632.1 - 1.7e-23 83.4 0.0 2.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG21632.1 - 7.5e-05 21.9 0.0 0.0021 17.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 OAG21632.1 - 0.0022 17.1 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG21632.1 - 0.0069 16.6 0.0 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glyco_hydro_17 PF00332.18 OAG21633.1 - 0.0022 17.6 0.5 0.032 13.8 0.3 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 DUF4562 PF15123.6 OAG21633.1 - 0.13 12.3 0.6 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) MFS_1 PF07690.16 OAG21635.1 - 2.9e-51 174.4 49.2 6.2e-50 170.1 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG21635.1 - 0.001 18.0 12.1 0.001 18.0 12.1 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter KID PF02524.14 OAG21635.1 - 0.22 11.7 0.2 3.3 8.2 0.0 2.7 3 0 0 3 3 3 0 KID repeat PPR_2 PF13041.6 OAG21637.1 - 5.3e-09 36.1 3.1 0.0049 17.0 0.1 5.3 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 OAG21637.1 - 0.0002 21.4 0.1 1.3 9.1 0.0 3.8 3 1 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 OAG21637.1 - 0.0013 18.8 1.2 6.2 7.3 0.1 4.8 4 0 0 4 4 4 2 PPR repeat BKACE PF05853.12 OAG21637.1 - 0.075 12.3 0.0 0.32 10.3 0.0 1.8 1 1 1 2 2 2 0 beta-keto acid cleavage enzyme Glyco_hydro_114 PF03537.13 OAG21638.1 - 3.8e-74 248.9 0.0 5e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CBM_1 PF00734.18 OAG21638.1 - 5.1e-07 29.5 15.4 5.1e-07 29.5 15.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2076 PF09849.9 OAG21639.1 - 3.2 7.7 12.3 4.7 7.2 12.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 OAG21640.1 - 5.4e-53 180.0 0.0 8.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21640.1 - 6.2e-33 114.2 0.0 9.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG21640.1 - 0.00059 18.7 0.0 0.00059 18.7 0.0 2.7 4 0 0 4 4 4 1 Fungal protein kinase APH PF01636.23 OAG21640.1 - 0.022 14.7 0.0 0.18 11.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OAG21640.1 - 0.031 13.9 0.8 0.3 10.7 0.0 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OAG21640.1 - 0.039 12.9 0.1 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OAG21640.1 - 0.039 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.6 OAG21642.1 - 7e-13 48.7 6.5 1.1e-12 48.1 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG21642.1 - 1.4e-09 37.5 0.6 2.4e-09 36.8 0.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG21642.1 - 7.1e-09 35.4 6.2 1.1e-08 34.7 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG21642.1 - 3.7e-08 33.1 3.5 6e-08 32.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG21642.1 - 6.2e-07 29.3 3.6 9.9e-07 28.6 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG21642.1 - 1.9e-06 28.1 9.8 1.7e-05 25.0 9.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG21642.1 - 4e-05 23.5 0.8 4e-05 23.5 0.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG21642.1 - 0.0005 19.9 2.5 0.00086 19.1 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG21642.1 - 0.0011 19.0 2.9 0.0026 17.7 2.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG21642.1 - 0.03 14.2 5.0 0.058 13.3 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAG21642.1 - 0.03 14.1 6.1 0.051 13.4 6.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAG21642.1 - 0.037 13.6 4.4 0.074 12.7 4.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAG21642.1 - 0.047 13.6 6.0 0.087 12.7 6.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OAG21642.1 - 0.047 13.9 4.6 0.095 12.9 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.13 OAG21642.1 - 0.11 13.1 4.1 0.43 11.2 0.0 2.9 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain FANCL_C PF11793.8 OAG21642.1 - 0.26 11.5 3.4 0.75 10.0 3.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OAG21642.1 - 0.37 10.9 5.7 0.78 9.8 5.7 1.6 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 OAG21642.1 - 0.5 10.5 5.5 1.1 9.5 5.5 1.6 1 0 0 1 1 1 0 RING-variant domain FAM176 PF14851.6 OAG21642.1 - 0.7 9.6 4.9 11 5.7 0.0 2.6 2 1 0 2 2 2 0 FAM176 family Prok-RING_1 PF14446.6 OAG21642.1 - 2.9 7.9 8.8 0.092 12.7 1.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 OAG21643.1 - 1.1e-50 172.0 0.9 1.2e-50 171.8 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRN3 PF05327.11 OAG21644.1 - 2.1e-173 577.9 0.0 2.1e-173 577.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAG21644.1 - 0.088 12.7 21.4 0.046 13.6 5.8 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region F-box-like PF12937.7 OAG21646.1 - 0.0037 17.1 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like Zip PF02535.22 OAG21648.1 - 2.5e-52 178.2 1.7 4.2e-52 177.4 1.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter ChaC PF04752.12 OAG21649.1 - 7.6e-33 114.1 0.1 2.4e-32 112.4 0.1 1.7 1 1 0 1 1 1 1 ChaC-like protein FAD_binding_3 PF01494.19 OAG21650.1 - 1.8e-26 93.3 0.1 8.6e-24 84.4 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG21650.1 - 1.4e-06 27.8 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG21650.1 - 0.00043 19.5 1.5 0.027 13.5 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 OAG21650.1 - 0.0034 16.5 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 OAG21650.1 - 0.0046 16.6 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG21650.1 - 0.04 14.5 0.1 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG21650.1 - 0.13 11.5 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family PX PF00787.24 OAG21653.1 - 1.9e-15 56.8 0.0 2.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 PX domain SAS4 PF15460.6 OAG21654.1 - 5.5e-33 113.0 1.7 8.6e-33 112.4 1.7 1.3 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 TFIIA PF03153.13 OAG21654.1 - 8.5 6.2 7.7 20 5.0 7.7 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EthD PF07110.11 OAG21657.1 - 7.9e-05 23.7 0.9 0.0012 20.0 0.9 2.0 1 1 0 1 1 1 1 EthD domain STI1 PF17830.1 OAG21657.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 STI1 domain HET PF06985.11 OAG21658.1 - 2.6e-31 109.0 3.0 5.1e-31 108.0 3.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-Paramyx-P PF13008.7 OAG21658.1 - 0.082 12.4 0.2 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein PH PF00169.29 OAG21659.1 - 0.00029 21.3 0.1 0.0015 19.0 0.0 2.1 2 0 0 2 2 2 1 PH domain EMC3_TMCO1 PF01956.16 OAG21659.1 - 0.038 13.7 6.5 0.069 12.9 6.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PHM7_cyt PF14703.6 OAG21659.1 - 7.7 6.7 10.0 1.8 8.8 2.5 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PHD PF00628.29 OAG21660.1 - 0.001 18.9 0.9 0.001 18.9 0.9 1.7 2 0 0 2 2 2 1 PHD-finger DUF4451 PF14616.6 OAG21660.1 - 0.032 14.5 0.8 0.65 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) zf-CSL PF05207.13 OAG21660.1 - 0.032 14.0 0.4 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 CSL zinc finger PHD_4 PF16866.5 OAG21660.1 - 0.044 13.9 3.5 0.063 13.4 0.2 2.6 3 0 0 3 3 3 0 PHD-finger Peptidase_M1_N PF17900.1 OAG21661.1 - 0.00029 21.1 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 OAG21661.1 - 0.17 11.4 0.3 0.33 10.5 0.3 1.5 1 1 0 1 1 1 0 Peptidase family M1 domain p450 PF00067.22 OAG21662.1 - 1.1e-96 324.5 0.0 1.2e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.20 OAG21663.1 - 7.3e-71 238.8 0.4 1.3e-70 238.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAG21663.1 - 1.4e-13 50.6 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAG21663.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG21663.1 - 0.0089 15.5 0.2 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) LTXXQ PF07813.12 OAG21663.1 - 0.026 15.2 5.9 0.059 14.1 5.9 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein MCM_N PF14551.6 OAG21663.1 - 0.061 13.9 0.1 0.21 12.2 0.1 1.9 1 0 0 1 1 1 0 MCM N-terminal domain CDH-cyt PF16010.5 OAG21665.1 - 2.8e-48 164.0 4.6 5.8e-48 163.0 4.6 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 OAG21665.1 - 0.004 16.8 1.9 0.16 11.5 0.0 3.4 4 0 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 OAG21665.1 - 0.017 14.4 0.0 0.47 9.6 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller NUC205 PF08168.11 OAG21665.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain PD40 PF07676.12 OAG21665.1 - 0.082 12.9 0.3 0.45 10.5 0.0 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MSP1_C PF07462.11 OAG21665.1 - 0.56 8.8 1.2 0.78 8.4 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Tmemb_14 PF03647.13 OAG21666.1 - 3.9e-23 82.0 8.8 4.7e-23 81.7 8.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 OAG21667.1 - 5.2e-49 165.1 3.0 6.2e-49 164.9 3.0 1.1 1 0 0 1 1 1 1 DAD family AWPM-19 PF05512.11 OAG21667.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AWPM-19-like family Aminotran_1_2 PF00155.21 OAG21668.1 - 1.8e-19 70.2 0.0 2.3e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG21668.1 - 2e-05 23.6 0.0 4.4e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Sel1 PF08238.12 OAG21669.1 - 4.9e-39 131.9 24.0 7.9e-07 29.6 0.4 7.5 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.15 OAG21670.1 - 1e-288 958.3 0.4 1.5e-288 957.7 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG21670.1 - 1.4e-13 51.2 4.4 6.2e-13 49.1 4.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG21670.1 - 1.3e-12 48.1 0.0 1.9e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG21670.1 - 0.00025 20.6 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG21670.1 - 0.0031 17.4 0.0 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sec61_beta PF03911.16 OAG21670.1 - 2.4 8.3 5.0 7.1 6.8 5.0 1.8 1 0 0 1 1 1 0 Sec61beta family WD40 PF00400.32 OAG21671.1 - 0.018 15.9 6.0 0.045 14.6 0.5 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 OAG21671.1 - 0.095 12.7 0.1 0.56 10.2 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ribosomal_S8e PF01201.22 OAG21672.1 - 9e-47 158.7 2.6 1.3e-46 158.2 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.21 OAG21673.1 - 4.1e-06 27.0 0.0 6.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Methyltransf_32 PF13679.6 OAG21673.1 - 0.03 14.3 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCI PF01399.27 OAG21674.1 - 2.8e-13 50.3 0.0 7.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 OAG21674.1 - 1.6e-05 24.7 0.4 3.3e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 OAG21674.1 - 0.035 14.6 1.5 6.5 7.3 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TFIIF_beta PF02270.15 OAG21675.1 - 1.8e-25 88.9 0.2 3.2e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OAG21675.1 - 4.4e-23 82.4 0.3 1.3e-22 81.0 0.0 1.9 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 OAG21675.1 - 1.6e-07 32.2 1.4 2.5e-07 31.6 1.4 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain AAA_5 PF07728.14 OAG21675.1 - 0.021 14.8 0.1 0.084 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sas10 PF09368.10 OAG21675.1 - 1.5 9.4 4.4 0.48 10.9 0.5 2.1 2 0 0 2 2 2 0 Sas10 C-terminal domain Questin_oxidase PF14027.6 OAG21677.1 - 5.2e-93 312.3 0.0 6.1e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Rtt106_N PF18215.1 OAG21678.1 - 0.014 15.1 0.3 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Git3 PF11710.8 OAG21679.1 - 1e-22 80.9 5.2 1.9e-22 80.1 5.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 OAG21679.1 - 3e-06 26.6 4.0 0.00062 19.0 4.0 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 OAG21679.1 - 0.0025 17.8 0.1 0.0025 17.8 0.1 2.3 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term CTNNBL PF08216.11 OAG21679.1 - 0.038 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DUF3659 PF12396.8 OAG21680.1 - 0 982.5 187.9 2.5e-24 84.9 4.0 15.6 15 0 0 15 15 15 15 Protein of unknown function (DUF3659) Alanine_zipper PF11839.8 OAG21680.1 - 0.0076 16.6 14.1 0.0076 16.6 14.1 7.8 6 1 1 7 7 7 1 Alanine-zipper, major outer membrane lipoprotein YtxH PF12732.7 OAG21680.1 - 0.027 15.0 71.2 0.14 12.7 9.3 8.7 5 2 1 6 6 6 0 YtxH-like protein RPW8 PF05659.11 OAG21680.1 - 0.85 9.3 2.5 0.79 9.4 0.2 2.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF883 PF05957.13 OAG21680.1 - 1.2 9.7 60.9 0.033 14.8 4.9 7.0 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF883) IQ PF00612.27 OAG21681.1 - 0.0014 18.3 3.2 0.0021 17.7 3.2 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif SMP PF04927.12 OAG21682.1 - 0.0048 17.3 1.7 0.0048 17.3 1.7 2.2 2 0 0 2 2 2 1 Seed maturation protein Cep57_MT_bd PF06657.13 OAG21682.1 - 0.067 13.7 4.2 6.3 7.3 0.2 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Wbp11 PF09429.10 OAG21682.1 - 6.4 7.3 6.7 0.7 10.3 0.5 2.6 3 0 0 3 3 3 0 WW domain binding protein 11 Fzo_mitofusin PF04799.13 OAG21682.1 - 6.8 6.2 5.9 2.3 7.8 0.2 2.5 3 0 0 3 3 3 0 fzo-like conserved region LRR_6 PF13516.6 OAG21683.1 - 1.4e-10 40.4 9.7 0.25 11.5 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 OAG21683.1 - 6.3e-05 23.3 13.1 0.55 10.7 1.6 5.2 2 2 5 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG21683.1 - 0.0012 19.1 0.2 34 5.5 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OAG21683.1 - 0.0055 16.4 8.5 0.46 10.3 0.0 4.6 3 2 0 3 3 3 1 Leucine rich repeat Suppressor_P21 PF11479.8 OAG21683.1 - 0.15 12.3 0.0 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain DUF604 PF04646.12 OAG21683.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 SDA1 PF05285.12 OAG21683.1 - 4.2 6.7 20.7 6.1 6.2 20.7 1.2 1 0 0 1 1 1 0 SDA1 COX17 PF05051.13 OAG21684.1 - 2.5e-19 69.4 6.8 3.8e-19 68.8 6.8 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Alg6_Alg8 PF03155.15 OAG21685.1 - 2.6e-126 422.4 24.5 2.3e-80 270.9 9.9 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 OAG21686.1 - 5.8e-45 151.0 0.1 3.7e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG21686.1 - 3.5e-07 30.0 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG21686.1 - 0.00034 20.7 0.0 0.95 9.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAG21686.1 - 0.00043 20.2 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAG21686.1 - 0.0014 18.2 0.0 0.17 11.5 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG21686.1 - 0.0082 16.2 0.0 0.53 10.4 0.0 3.0 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 OAG21686.1 - 0.01 15.9 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Limkain b1 MFS_1 PF07690.16 OAG21687.1 - 5.7e-18 65.0 19.2 5.7e-18 65.0 19.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG21687.1 - 8.2e-06 24.9 2.9 8.2e-06 24.9 2.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Sox17_18_mid PF12067.8 OAG21688.1 - 0.02 14.9 3.0 0.22 11.6 2.6 2.4 1 1 0 1 1 1 0 Sox 17/18 central domain zf-C2H2 PF00096.26 OAG21690.1 - 0.0062 16.9 5.6 0.0062 16.9 5.6 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type C1_4 PF07975.12 OAG21690.1 - 0.093 13.0 0.3 0.23 11.7 0.3 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 OAG21690.1 - 0.61 9.9 12.5 0.03 14.1 2.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OAG21690.1 - 1.4 10.0 17.0 0.092 13.6 4.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG21690.1 - 4.7 7.3 5.6 1.3 9.1 2.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger MRJP PF03022.16 OAG21691.1 - 4.8e-07 29.4 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OAG21691.1 - 0.057 13.0 0.8 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region HECT_2 PF09814.9 OAG21692.1 - 5.2e-105 351.4 0.0 6e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding 3Beta_HSD PF01073.19 OAG21693.1 - 2e-69 233.7 0.0 2.6e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG21693.1 - 2e-28 99.5 0.1 2.7e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG21693.1 - 8.4e-20 71.4 0.0 4.5e-17 62.5 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG21693.1 - 7e-13 48.3 0.0 2.1e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 OAG21693.1 - 6.2e-10 39.3 0.0 8.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG21693.1 - 1.5e-09 37.4 0.1 4e-09 36.0 0.1 1.7 1 1 1 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG21693.1 - 4.2e-09 35.9 0.0 2e-08 33.8 0.1 2.1 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG21693.1 - 6.1e-07 29.2 0.1 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OAG21693.1 - 9.7e-07 28.9 0.2 1.4e-05 25.1 0.2 2.4 1 1 0 1 1 1 1 KR domain UQ_con PF00179.26 OAG21694.1 - 9.2e-42 142.0 0.0 1.9e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG21694.1 - 3.7e-06 26.7 0.0 0.00023 20.9 0.0 2.8 2 1 0 2 2 2 1 Prokaryotic E2 family B UEV PF05743.13 OAG21694.1 - 0.09 12.6 0.0 0.39 10.6 0.0 2.0 2 1 1 3 3 3 0 UEV domain Sybindin PF04099.12 OAG21695.1 - 5.3e-50 169.1 0.0 6.2e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAG21695.1 - 4.6e-10 39.7 0.2 9.8e-10 38.7 0.2 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region ACOX PF01756.19 OAG21695.1 - 0.16 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA oxidase VWA_2 PF13519.6 OAG21696.1 - 4.1e-22 78.8 0.0 9.8e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAG21696.1 - 4.8e-07 30.2 0.2 6.7e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAG21696.1 - 3.4e-06 27.0 0.1 4.6e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OAG21696.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 OAG21697.1 - 7.5e-15 54.3 1.5 1.2e-14 53.7 1.5 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DHHA2 PF02833.14 OAG21698.1 - 5.2e-16 59.1 0.0 8.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OAG21698.1 - 1e-09 38.5 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 DHH family DUF2569 PF10754.9 OAG21699.1 - 0.044 14.2 0.3 0.051 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF5506 PF17611.2 OAG21699.1 - 0.18 11.7 1.3 0.27 11.1 0.3 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5506) AZUL PF16558.5 OAG21699.1 - 1.5 9.1 5.4 2.2 8.6 5.4 1.2 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF2985 PF11204.8 OAG21700.1 - 5.3e-25 87.4 7.6 9.1e-25 86.6 7.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Mucin PF01456.17 OAG21700.1 - 7.1 6.6 20.4 14 5.7 20.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein HLH PF00010.26 OAG21701.1 - 5.8e-14 51.8 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SnoaL PF07366.12 OAG21703.1 - 0.034 14.0 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Dehydrin PF00257.19 OAG21703.1 - 0.26 11.8 5.6 0.75 10.3 5.6 1.8 1 0 0 1 1 1 0 Dehydrin F-box-like PF12937.7 OAG21705.1 - 0.0063 16.4 1.2 0.027 14.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like OTT_1508_deam PF14441.6 OAG21705.1 - 0.1 12.6 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 OTT_1508-like deaminase Cytomega_UL84 PF06284.11 OAG21705.1 - 5.4 5.4 5.8 7.1 5.0 5.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pkinase PF00069.25 OAG21706.1 - 5e-38 131.0 0.0 4.7e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21706.1 - 8.1e-17 61.4 0.0 5.8e-16 58.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG21706.1 - 6.7e-05 22.9 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG21706.1 - 0.024 14.0 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF2235 PF09994.9 OAG21707.1 - 8.8e-84 281.3 0.0 1.2e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 OAG21708.1 - 9.3e-21 74.0 0.1 1.5e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21708.1 - 0.00014 21.9 6.9 0.00024 21.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_12 PF01670.16 OAG21709.1 - 1.4e-65 221.3 11.3 1.6e-65 221.1 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 TraD_N PF12615.8 OAG21709.1 - 0.067 14.0 2.5 0.44 11.4 2.5 2.2 1 1 0 1 1 1 0 F sex factor protein N terminal pRN1_helical PF13010.6 OAG21709.1 - 0.19 11.7 0.1 0.44 10.5 0.0 1.5 2 0 0 2 2 2 0 Primase helical domain CKS PF01111.19 OAG21710.1 - 5.2e-35 119.5 0.5 5.2e-35 119.5 0.5 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.11 OAG21710.1 - 0.41 11.0 2.7 2.5 8.5 0.3 2.5 2 0 0 2 2 2 0 APC 15 residue motif TFIIA PF03153.13 OAG21713.1 - 2 8.3 10.1 2.3 8.1 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 OAG21714.1 - 1.1e-14 55.0 0.0 8.4e-14 52.1 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OAG21714.1 - 3.8e-13 49.7 0.0 7.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAG21714.1 - 7.6e-13 48.6 0.0 1e-11 44.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG21714.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 OAG21714.1 - 1.4e-05 24.9 0.0 4e-05 23.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG21714.1 - 1.6e-05 25.2 0.0 5e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG21714.1 - 2.9e-05 24.5 0.0 0.00084 19.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 OAG21714.1 - 3.4e-05 23.8 0.0 7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OAG21714.1 - 8.1e-05 22.9 0.6 0.00026 21.3 0.1 2.1 2 0 0 2 2 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 OAG21714.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAG21714.1 - 0.00044 20.6 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAG21714.1 - 0.00065 19.0 0.0 0.0014 18.0 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 OAG21714.1 - 0.0029 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG21714.1 - 0.004 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 OAG21714.1 - 0.0064 16.2 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG21714.1 - 0.0086 16.1 0.5 0.062 13.3 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAG21714.1 - 0.018 14.7 0.1 0.11 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAG21714.1 - 0.029 14.4 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG21714.1 - 0.031 14.8 0.0 0.11 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG21714.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAG21714.1 - 0.052 13.5 0.0 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAG21714.1 - 0.066 13.1 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG21714.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 OAG21714.1 - 0.13 12.0 0.1 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 OAG21714.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Ribosomal_60s PF00428.19 OAG21714.1 - 8.4 7.1 10.9 0.4 11.3 3.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3734 PF12536.8 OAG21715.1 - 0.0029 17.9 3.5 0.2 12.0 1.0 2.4 2 0 0 2 2 2 2 Patatin phospholipase AIG1 PF04548.16 OAG21716.1 - 4.8e-11 42.4 0.1 6.8e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OAG21716.1 - 3.4e-08 33.6 0.0 5.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG21716.1 - 0.00027 21.0 3.0 0.072 13.2 0.1 2.5 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAG21716.1 - 0.00031 20.7 0.1 0.00061 19.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 OAG21716.1 - 0.007 15.7 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Septin Viral_helicase1 PF01443.18 OAG21716.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 OAG21716.1 - 0.056 14.0 0.1 0.24 11.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter GBP PF02263.19 OAG21716.1 - 0.073 12.3 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.6 OAG21716.1 - 0.073 13.3 0.2 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.20 OAG21717.1 - 5.4e-14 51.3 0.1 4.1e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG21717.1 - 0.0031 16.4 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein C8 PF08742.11 OAG21717.1 - 0.043 14.2 0.2 0.086 13.3 0.2 1.4 1 0 0 1 1 1 0 C8 domain DUF3844 PF12955.7 OAG21719.1 - 1.3e-33 115.3 3.5 2e-33 114.7 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Sec66 PF09802.9 OAG21720.1 - 1.1e-80 269.5 1.1 1.3e-80 269.3 1.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 OAG21720.1 - 0.0086 16.1 0.6 0.019 15.0 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 OAG21720.1 - 0.028 14.6 2.2 0.05 13.8 1.9 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TBCC_N PF16752.5 OAG21720.1 - 0.15 12.5 2.4 0.44 11.0 0.9 2.2 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain FUSC PF04632.12 OAG21720.1 - 0.3 9.6 4.1 0.42 9.1 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPL4 PF05021.15 OAG21721.1 - 2.1e-135 451.0 0.0 2.7e-135 450.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OAG21721.1 - 7.7e-67 223.9 0.1 1.2e-66 223.4 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAG21721.1 - 0.017 15.6 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 E1-E2_ATPase PF00122.20 OAG21722.1 - 1.7e-49 167.8 1.6 2.9e-49 167.0 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG21722.1 - 2.8e-37 129.1 1.2 8.1e-37 127.5 1.2 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG21722.1 - 1.3e-33 115.3 0.2 8.1e-13 48.6 0.1 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OAG21722.1 - 6.7e-07 29.3 0.4 0.00029 20.6 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 OAG21722.1 - 6.2 6.9 10.7 10 6.3 2.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Glyco_hydro_cc PF11790.8 OAG21723.1 - 1.3e-59 201.7 4.1 1.5e-59 201.5 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.17 OAG21723.1 - 0.032 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ank_4 PF13637.6 OAG21724.1 - 0.0088 16.6 0.0 0.25 12.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Linocin_M18 PF04454.12 OAG21724.1 - 0.042 13.1 0.1 0.075 12.3 0.1 1.4 2 0 0 2 2 2 0 Encapsulating protein for peroxidase Rad17 PF03215.15 OAG21725.1 - 6e-31 107.8 0.0 1.6e-30 106.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAG21725.1 - 0.0014 19.0 0.1 0.0038 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OAG21725.1 - 0.0022 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG21725.1 - 0.0053 17.2 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG21725.1 - 0.0054 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG21725.1 - 0.0093 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 OAG21725.1 - 0.02 14.7 0.0 0.093 12.5 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG21725.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 OAG21725.1 - 0.049 14.0 0.0 0.16 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG21725.1 - 0.057 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG21725.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OAG21725.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 OAG21725.1 - 0.13 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 OAG21725.1 - 0.14 12.1 0.1 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Lectin_N PF03954.14 OAG21726.1 - 6.3 6.6 7.5 0.69 9.7 1.6 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain UQ_con PF00179.26 OAG21727.1 - 4.4e-26 91.2 0.1 5.6e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG21727.1 - 7.2e-07 29.0 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG21727.1 - 0.0073 16.2 0.1 0.0094 15.8 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OAG21727.1 - 0.022 15.1 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain Peroxin-13_N PF04088.13 OAG21728.1 - 8.5e-51 172.1 0.3 1.5e-50 171.3 0.3 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 OAG21728.1 - 6.8e-11 41.6 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG21728.1 - 2e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAG21728.1 - 9.6e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DEC-1_N PF04625.13 OAG21728.1 - 0.038 13.0 0.9 0.074 12.1 0.9 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pex2_Pex12 PF04757.14 OAG21728.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region hSH3 PF14603.6 OAG21728.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Mlf1IP PF10248.9 OAG21728.1 - 1.8 8.5 5.9 1.1 9.3 2.8 2.2 2 1 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF2401 PF10287.9 OAG21729.1 - 1.3e-73 247.4 0.1 2.2e-73 246.6 0.1 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 OAG21729.1 - 0.0042 17.5 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Ribosomal_S13_N PF08069.12 OAG21730.1 - 2.8e-29 100.9 0.1 4.8e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAG21730.1 - 8.2e-15 54.8 0.1 1.2e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAG21730.1 - 0.013 15.5 0.1 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 OAG21731.1 - 2.5e-12 46.3 0.2 4.8e-12 45.4 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif Sec1 PF00995.23 OAG21732.1 - 1.3e-96 325.1 0.0 1.4e-96 325.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NAD_binding_10 PF13460.6 OAG21733.1 - 3.7e-18 66.1 0.0 4.3e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG21733.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG21733.1 - 0.006 16.1 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAG21734.1 - 1.6e-07 31.3 13.7 3.7e-07 30.2 13.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG21734.1 - 6.2e-06 25.4 0.1 1.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NinD PF17466.2 OAG21734.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function GST_N PF02798.20 OAG21735.1 - 1.5e-15 57.2 0.0 3.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG21735.1 - 3.1e-11 43.5 0.0 4.1e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG21735.1 - 9.7e-10 38.5 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG21735.1 - 2.2e-08 34.3 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG21735.1 - 1.5e-06 28.1 0.3 7.1e-06 26.0 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG21735.1 - 0.003 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease_2 PF13520.6 OAG21737.1 - 1.8e-63 214.8 41.8 2.2e-63 214.6 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG21737.1 - 1.5e-17 63.4 35.2 2.2e-17 62.8 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.16 OAG21738.1 - 1.1e-31 110.7 0.4 1.1e-31 110.7 0.4 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_trans_4_4 PF13579.6 OAG21738.1 - 0.088 13.2 0.1 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain CsiD PF08943.10 OAG21738.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 CsiD Pkinase PF00069.25 OAG21739.1 - 1.6e-31 109.6 0.0 8.7e-31 107.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21739.1 - 2.9e-06 26.8 0.1 3e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG21739.1 - 0.0011 19.0 0.1 0.0021 18.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG21739.1 - 0.0058 15.5 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase IL28A PF15177.6 OAG21741.1 - 0.0035 17.2 0.8 0.082 12.7 0.2 2.9 2 0 0 2 2 2 1 Interleukin-28A Baculo_PEP_C PF04513.12 OAG21741.1 - 0.45 10.6 2.3 0.48 10.5 0.1 2.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 OAG21742.1 - 5.2e-18 65.8 0.0 1.1e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG21742.1 - 0.0028 18.1 0.1 0.0028 18.1 0.1 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 OAG21742.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG21742.1 - 0.04 14.2 0.2 0.34 11.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 OAG21742.1 - 0.3 10.9 1.6 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein HSP70 PF00012.20 OAG21743.1 - 3.7e-225 748.7 10.5 4.2e-225 748.5 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG21743.1 - 9.4e-18 64.1 0.4 7.5e-17 61.1 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAG21743.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 OAG21743.1 - 0.084 12.4 1.0 0.43 10.0 1.0 2.2 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Vta1 PF04652.16 OAG21744.1 - 1.9e-47 160.9 4.0 8.5e-47 158.8 3.6 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAG21744.1 - 3.7e-14 52.1 0.6 8.7e-14 50.9 0.6 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain Thioredoxin PF00085.20 OAG21745.1 - 5.7e-31 106.6 0.1 3.8e-25 87.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OAG21745.1 - 5.5e-08 32.5 0.0 1.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAG21745.1 - 0.00028 21.3 3.4 0.053 14.0 0.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 OAG21745.1 - 0.0056 16.5 9.0 0.031 14.1 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAG21745.1 - 0.006 16.9 0.0 2.4 8.5 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like QSOX_Trx1 PF18108.1 OAG21745.1 - 0.0071 16.5 0.0 0.033 14.4 0.0 2.1 3 0 0 3 3 3 1 QSOX Trx-like domain HTH_6 PF01418.17 OAG21745.1 - 0.017 15.1 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family RAP1 PF07218.11 OAG21745.1 - 0.83 7.9 4.3 1.3 7.3 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M28 PF04389.17 OAG21746.1 - 2.2e-21 76.4 0.0 5e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 OAG21746.1 - 1.1e-16 61.0 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 OAG21746.1 - 4.6e-09 36.2 0.2 1.3e-08 34.7 0.2 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 OAG21746.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 OAG21746.1 - 0.15 11.5 0.0 0.49 9.8 0.0 1.7 2 0 0 2 2 2 0 Nicastrin VirE3 PF06661.11 OAG21747.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 VirE3 HnRNPA1 PF11627.8 OAG21747.1 - 2.9 8.1 4.6 6.7 7.0 0.9 3.0 3 0 0 3 3 3 0 Nuclear factor hnRNPA1 Glyco_transf_34 PF05637.12 OAG21748.1 - 2e-23 83.3 0.2 1.4e-21 77.3 0.2 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family zf-GRF PF06839.12 OAG21749.1 - 5.8e-07 29.5 6.4 1.1e-06 28.6 6.4 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF2390 PF09523.10 OAG21749.1 - 0.11 12.9 0.5 0.19 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Mto2_bdg PF12808.7 OAG21749.1 - 0.11 12.8 0.6 0.25 11.7 0.6 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMF_DNA_bd PF12329.8 OAG21749.1 - 0.16 12.0 0.6 0.28 11.2 0.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SNF PF00209.18 OAG21750.1 - 1.2e-76 258.5 39.1 2.5e-76 257.5 30.8 3.0 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family HMA PF00403.26 OAG21751.1 - 0.00028 21.3 0.1 0.00049 20.5 0.1 1.4 1 1 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 OAG21751.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 E1-E2_ATPase PF00122.20 OAG21752.1 - 2.2e-52 177.2 1.5 3.5e-51 173.3 0.0 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG21752.1 - 3e-36 125.7 0.1 2.3e-35 122.8 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG21752.1 - 2.2e-25 88.9 0.1 4.9e-11 42.9 0.1 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 OAG21752.1 - 0.00023 21.6 0.0 0.00057 20.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG21752.1 - 0.00063 19.6 0.2 0.0017 18.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase APOBEC2 PF18772.1 OAG21752.1 - 0.041 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 APOBEC2 zf-met PF12874.7 OAG21753.1 - 1.7e-10 40.9 7.6 0.00032 21.0 0.0 3.8 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG21753.1 - 2.1e-07 31.2 19.9 0.0013 19.4 0.3 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG21753.1 - 1.7e-06 27.9 10.8 0.0069 16.4 0.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG21753.1 - 3.6e-05 24.0 8.6 0.024 15.1 1.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAG21753.1 - 3.9e-05 23.9 5.5 0.00027 21.2 0.5 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG21753.1 - 7.4e-05 22.9 2.8 0.017 15.4 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding LIM PF00412.22 OAG21753.1 - 0.00038 20.6 5.6 0.00038 20.6 5.6 2.5 3 0 0 3 3 2 1 LIM domain zf-C2H2_2 PF12756.7 OAG21753.1 - 0.00094 19.5 12.4 1.2 9.5 0.3 3.3 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OAG21753.1 - 0.0044 16.7 0.4 0.0044 16.7 0.4 3.7 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-MYST PF17772.1 OAG21753.1 - 0.066 12.8 5.7 0.33 10.6 0.0 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain DUF2256 PF10013.9 OAG21753.1 - 0.075 13.2 8.4 4.1 7.6 0.1 3.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 OAG21753.1 - 0.14 11.8 10.3 3.4 7.3 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 OAG21753.1 - 1.2 9.4 11.1 21 5.4 6.6 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 OAG21753.1 - 5.6 7.0 11.8 0.29 11.1 4.0 2.6 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-HC5HC2H_2 PF13832.6 OAG21754.1 - 1.3 9.2 7.9 0.57 10.4 1.3 2.7 2 1 0 2 2 2 0 PHD-zinc-finger like domain p450 PF00067.22 OAG21755.1 - 9.6e-61 205.9 0.0 1.3e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAG21756.1 - 4.8e-11 42.6 7.4 7.8e-11 41.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_6 PF13977.6 OAG21757.1 - 0.035 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Fungal_trans PF04082.18 OAG21757.1 - 0.048 12.7 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CENP-I PF07778.11 OAG21757.1 - 0.073 11.8 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Mis6 Coiled-coil_56 PF09813.9 OAG21761.1 - 2.2e-06 27.6 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 OAG21762.1 - 1.9e-66 223.9 0.2 5.5e-66 222.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Beta-lactamase PF00144.24 OAG21765.1 - 2.9e-31 108.9 1.2 1.6e-30 106.5 1.2 1.9 1 1 0 1 1 1 1 Beta-lactamase Aldolase_II PF00596.21 OAG21766.1 - 2e-47 161.5 0.0 2.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3602 PF12223.8 OAG21767.1 - 2.1e-21 76.3 16.5 1.6e-20 73.5 7.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) HRCT1 PF15758.5 OAG21767.1 - 0.039 14.9 0.2 0.052 14.5 0.2 1.2 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 DUF1295 PF06966.12 OAG21768.1 - 5.6e-56 189.7 1.5 7.2e-56 189.3 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAG21768.1 - 6.6e-06 26.2 0.2 6.6e-06 26.2 0.2 3.5 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAG21768.1 - 2.8e-05 24.5 1.7 2.9e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG21768.1 - 0.02 15.2 0.4 0.02 15.2 0.4 2.8 2 1 0 2 2 2 0 Phospholipid methyltransferase RNase_P_p30 PF01876.16 OAG21771.1 - 1.4e-51 175.0 0.0 1.9e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.25 OAG21772.1 - 1e-66 225.1 0.1 1.2e-66 224.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21772.1 - 4.4e-20 72.0 0.0 6.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG21772.1 - 1.1e-07 32.0 0.1 3.1e-05 24.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG21772.1 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG21772.1 - 0.004 16.0 0.0 0.0077 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG21772.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG21772.1 - 0.052 13.1 0.2 0.052 13.1 0.2 1.9 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 OAG21773.1 - 1.7e-222 740.0 0.0 4e-221 735.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG21773.1 - 1.6e-32 112.5 0.2 1.6e-32 112.5 0.2 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG21773.1 - 4.1e-16 58.7 0.9 8.9e-07 28.0 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAG21773.1 - 3.9e-10 39.6 3.5 2.6e-08 33.6 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAG21773.1 - 0.0067 15.8 1.6 0.3 10.4 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Abhydrolase_6 PF12697.7 OAG21774.1 - 1.8e-17 64.7 2.0 2.3e-17 64.4 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FerA PF08165.11 OAG21774.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 FerA (NUC095) domain Ank_3 PF13606.6 OAG21775.1 - 8.7e-08 31.9 0.0 0.83 10.4 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OAG21775.1 - 2.6e-07 31.0 0.0 0.012 16.1 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG21775.1 - 4.6e-06 27.1 0.0 0.89 10.2 0.0 3.4 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG21775.1 - 0.013 15.8 0.1 8.8 6.8 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) NmrA PF05368.13 OAG21776.1 - 1.1e-19 71.0 0.0 3.3e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG21776.1 - 4.3e-17 62.6 0.1 6.2e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OAG21776.1 - 5.3e-05 23.5 0.1 0.0001 22.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 OAG21776.1 - 0.0062 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG21776.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAG21776.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 OAG21776.1 - 0.026 14.0 0.1 0.048 13.1 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21776.1 - 0.079 12.5 0.2 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 OAG21776.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG21776.1 - 0.12 12.3 0.0 6.1 6.7 0.0 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WSC PF01822.19 OAG21777.1 - 7.5e-15 54.9 8.2 2.2e-14 53.4 8.2 1.9 1 0 0 1 1 1 1 WSC domain Fungal_trans PF04082.18 OAG21779.1 - 3.9e-16 58.9 0.0 6.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG21779.1 - 4.1e-08 33.2 9.6 4.1e-08 33.2 9.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG21780.1 - 2e-37 129.0 37.4 2e-37 129.0 37.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 OAG21780.1 - 0.013 15.0 1.5 0.013 15.0 1.5 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein Abhydrolase_1 PF00561.20 OAG21781.1 - 5.7e-19 68.8 0.0 7.3e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG21781.1 - 2.4e-18 67.5 0.0 3.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG21781.1 - 5.5e-08 32.4 0.0 7.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 OAG21781.1 - 1.4e-05 24.5 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 OAG21781.1 - 0.00019 21.2 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 OAG21781.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ndr PF03096.14 OAG21781.1 - 0.0025 16.5 0.0 0.22 10.2 0.0 2.1 2 0 0 2 2 2 2 Ndr family Palm_thioest PF02089.15 OAG21781.1 - 0.0028 17.5 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Thioesterase PF00975.20 OAG21781.1 - 0.0039 17.3 0.0 0.0089 16.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 OAG21781.1 - 0.0067 16.2 0.1 0.032 14.0 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 OAG21781.1 - 0.013 15.4 0.1 0.72 9.6 0.1 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 OAG21781.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ADH_zinc_N PF00107.26 OAG21782.1 - 1.1e-24 86.8 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG21782.1 - 6.4e-24 83.9 0.6 1e-23 83.3 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 OAG21782.1 - 0.00073 19.1 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 OAG21782.1 - 0.005 17.9 0.0 0.012 16.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG21782.1 - 0.1 12.0 0.3 0.16 11.3 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA PF00004.29 OAG21783.1 - 3.4e-52 176.3 0.0 3.5e-43 147.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG21783.1 - 4.8e-05 23.8 1.7 0.024 15.0 0.0 4.1 3 1 0 4 4 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 OAG21783.1 - 5.8e-05 22.8 4.7 0.014 15.2 0.0 2.9 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 OAG21783.1 - 0.00017 21.4 0.1 0.00057 19.7 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG21783.1 - 0.00051 20.4 0.0 0.029 14.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.17 OAG21783.1 - 0.00061 19.0 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAG21783.1 - 0.0042 16.7 0.0 0.068 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG21783.1 - 0.0062 16.8 0.0 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAG21783.1 - 0.0069 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAG21783.1 - 0.0072 16.5 0.0 0.44 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAG21783.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OAG21783.1 - 0.01 16.4 0.0 0.11 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG21783.1 - 0.017 15.6 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG21783.1 - 0.021 14.8 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OAG21783.1 - 0.024 14.0 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 OAG21783.1 - 0.039 14.0 2.2 0.59 10.2 0.2 3.6 4 1 0 4 4 3 0 Vps4 C terminal oligomerisation domain ATPase PF06745.13 OAG21783.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 OAG21783.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAG21783.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG21783.1 - 0.061 13.0 0.6 0.98 9.1 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 OAG21783.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 OAG21783.1 - 0.082 12.1 0.0 3.1 6.9 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain PhoH PF02562.16 OAG21783.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAG21783.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydro_lipase PF04083.16 OAG21784.1 - 3e-18 65.1 0.0 8.1e-18 63.8 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAG21784.1 - 2.6e-07 30.5 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG21784.1 - 0.0016 17.7 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 HTH_48 PF17906.1 OAG21784.1 - 0.03 14.4 0.4 0.35 11.0 0.1 2.6 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF900 PF05990.12 OAG21784.1 - 0.17 11.4 0.0 0.93 8.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Tubulin PF00091.25 OAG21785.1 - 3.2e-65 220.0 0.0 4.4e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG21785.1 - 9.6e-44 148.6 0.0 1.5e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAG21785.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 OAG21786.1 - 3.6e-22 78.9 1.6 6.2e-22 78.2 1.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 OAG21786.1 - 0.0001 21.6 0.0 0.00025 20.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OAG21786.1 - 0.0013 18.1 0.1 0.003 17.0 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG21786.1 - 0.0024 17.7 0.0 0.0074 16.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAG21786.1 - 0.012 16.0 0.1 0.03 14.8 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair TraG_N PF07916.11 OAG21786.1 - 2.9 6.6 6.3 0.93 8.3 0.0 2.2 2 0 0 2 2 2 0 TraG-like protein, N-terminal region NmrA PF05368.13 OAG21788.1 - 1.4e-15 57.5 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG21788.1 - 1.7e-14 54.1 0.1 4.7e-14 52.7 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG21788.1 - 6.5e-08 32.3 0.1 2.3e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG21788.1 - 8.8e-07 29.0 0.4 1.2e-06 28.5 0.4 1.2 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 OAG21788.1 - 0.0002 21.5 0.8 0.00068 19.7 0.3 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OAG21788.1 - 0.0018 17.5 0.3 0.0029 16.8 0.3 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 OAG21788.1 - 0.012 15.7 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG21788.1 - 0.027 15.0 0.1 0.058 14.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG21788.1 - 0.029 14.6 0.2 0.049 13.9 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 OAG21788.1 - 0.073 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CbiJ PF02571.14 OAG21788.1 - 0.081 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Polysacc_synt_2 PF02719.15 OAG21788.1 - 0.081 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LpxI_N PF17930.1 OAG21788.1 - 0.11 12.4 0.6 0.32 10.9 0.2 1.9 2 0 0 2 2 2 0 LpxI N-terminal domain adh_short PF00106.25 OAG21788.1 - 0.19 11.1 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.18 OAG21790.1 - 3.3e-08 32.9 0.4 3.3e-08 32.9 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain HET PF06985.11 OAG21791.1 - 1e-27 97.3 0.0 2.4e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CBM_11 PF03425.13 OAG21792.1 - 0.084 12.7 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) ParBc_2 PF08857.11 OAG21792.1 - 0.16 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative ParB-like nuclease DUF2370 PF10176.9 OAG21793.1 - 0.18 11.4 0.7 0.33 10.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Lactamase_B_3 PF13483.6 OAG21794.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CbbQ_C PF08406.10 OAG21795.1 - 0.034 14.4 0.4 0.062 13.6 0.4 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal Herpes_US9 PF06072.11 OAG21795.1 - 5.4 7.0 9.6 8.4 6.4 1.3 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 AA_permease_2 PF13520.6 OAG21796.1 - 4.1e-45 154.4 48.1 4.9e-45 154.1 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG21796.1 - 1.4e-24 86.6 30.2 1.4e-24 86.6 30.2 1.5 2 0 0 2 2 2 1 Amino acid permease fn3_4 PF16794.5 OAG21797.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 1 1 1 2 2 2 0 Fibronectin-III type domain Scm3 PF10384.9 OAG21799.1 - 9.2e-16 57.3 3.9 1.2e-15 57.0 0.6 2.4 2 0 0 2 2 2 1 Centromere protein Scm3 CorA PF01544.18 OAG21799.1 - 0.074 12.4 1.6 0.12 11.7 1.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6 PF04111.12 OAG21800.1 - 8.7e-69 231.1 0.0 1.3e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAG21800.1 - 5e-35 120.9 6.4 7.8e-35 120.3 6.4 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4686 PF15742.5 OAG21800.1 - 0.0044 16.2 2.3 0.0062 15.7 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DUF4472 PF14739.6 OAG21800.1 - 0.0077 16.9 5.2 0.017 15.9 5.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) CdvA PF18822.1 OAG21800.1 - 0.008 16.0 1.9 0.016 15.1 1.9 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain GOLGA2L5 PF15070.6 OAG21800.1 - 0.012 14.3 4.9 0.016 13.9 4.9 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 HIP1_clath_bdg PF16515.5 OAG21800.1 - 0.026 15.1 6.7 0.099 13.3 0.8 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HAUS-augmin3 PF14932.6 OAG21800.1 - 0.087 12.4 6.1 0.14 11.7 6.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Rho_Binding PF08912.11 OAG21800.1 - 0.34 11.7 3.2 0.8 10.6 3.2 1.7 1 0 0 1 1 1 0 Rho Binding FUSC PF04632.12 OAG21800.1 - 1.5 7.3 5.1 2.8 6.4 5.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box PF00646.33 OAG21801.1 - 0.022 14.7 0.3 3.5 7.6 0.2 3.1 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 OAG21801.1 - 0.085 13.0 0.5 8.1 6.8 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 OAG21801.1 - 0.26 11.8 1.8 99 3.6 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) FMN_red PF03358.15 OAG21802.1 - 4.3e-11 42.8 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAG21802.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 OAG21802.1 - 0.0018 18.5 0.2 0.029 14.6 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 OAG21802.1 - 0.024 14.9 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Phosphodiest PF01663.22 OAG21803.1 - 6.4e-91 305.6 0.7 8.7e-91 305.2 0.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG21803.1 - 0.0011 18.4 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Sulfatase eIF-3_zeta PF05091.12 OAG21805.1 - 2.5e-202 673.5 0.0 2.8e-202 673.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 OAG21805.1 - 0.079 12.6 0.0 0.26 11.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF569) HET PF06985.11 OAG21806.1 - 1.2e-34 119.8 1.1 1.6e-34 119.3 1.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.6 OAG21806.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) DUF3176 PF11374.8 OAG21809.1 - 0.13 12.5 0.5 0.34 11.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Pkinase PF00069.25 OAG21810.1 - 1.6e-21 76.9 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21810.1 - 4.3e-13 49.1 0.0 6.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG21810.1 - 9.5e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG21810.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAG21810.1 - 0.038 13.9 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAG21810.1 - 0.18 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NmrA PF05368.13 OAG21813.1 - 5.7e-19 68.6 0.0 7.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG21813.1 - 2.2e-13 50.5 0.0 4.2e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Aerolysin PF01117.20 OAG21814.1 - 0.00021 20.6 7.7 0.00029 20.1 7.7 1.2 1 0 0 1 1 1 1 Aerolysin toxin GramPos_pilinBB PF16569.5 OAG21814.1 - 0.14 13.0 6.4 0.064 14.1 1.9 2.4 1 1 1 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain CDP-OH_P_transf PF01066.21 OAG21816.1 - 3e-15 56.7 0.1 3e-15 56.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.24 OAG21817.1 - 1.9e-20 72.9 2.0 7e-20 71.1 0.8 2.6 3 1 0 3 3 3 1 PX domain Vps5 PF09325.10 OAG21817.1 - 1.5e-10 41.0 7.2 5.6e-06 26.1 1.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 OAG21817.1 - 0.0023 17.7 5.0 0.063 13.0 0.3 2.3 2 0 0 2 2 2 2 BAR domain of APPL family Sec34 PF04136.15 OAG21817.1 - 0.0027 17.6 1.1 0.0067 16.3 1.1 1.7 1 0 0 1 1 1 1 Sec34-like family BAR PF03114.18 OAG21817.1 - 0.019 14.6 10.0 0.09 12.4 7.8 2.5 2 1 0 2 2 2 0 BAR domain EcsC PF12787.7 OAG21817.1 - 0.039 13.6 0.1 0.079 12.6 0.1 1.6 1 0 0 1 1 1 0 EcsC protein family PIN_8 PF18476.1 OAG21817.1 - 1.1 9.1 9.7 0.047 13.5 0.8 2.4 3 0 0 3 3 3 0 PIN like domain Rx_N PF18052.1 OAG21817.1 - 5.9 7.2 7.7 53 4.2 0.0 3.9 3 1 1 4 4 4 0 Rx N-terminal domain ADK PF00406.22 OAG21818.1 - 1.8e-37 128.8 0.0 6.8e-20 71.7 0.0 2.1 1 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OAG21818.1 - 6.9e-15 55.7 0.0 2.4e-10 41.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain ADK_lid PF05191.14 OAG21818.1 - 1.3e-14 53.9 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG21818.1 - 3.6e-05 24.3 0.0 0.00019 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG21818.1 - 0.019 15.2 0.0 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAG21818.1 - 0.043 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OAG21818.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OAG21818.1 - 0.2 10.5 0.1 0.3 9.9 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain LETM1 PF07766.13 OAG21819.1 - 6.7e-104 347.0 0.0 6.7e-104 347.0 0.0 1.9 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 OAG21819.1 - 0.00012 21.7 0.0 0.006 16.3 0.0 3.2 3 0 0 3 3 3 1 SAP domain DUF676 PF05057.14 OAG21821.1 - 2.7e-05 23.8 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG21821.1 - 0.00022 21.9 0.0 0.00027 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG21821.1 - 0.00028 20.7 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF818 PF05677.12 OAG21821.1 - 0.00047 19.2 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.25 OAG21821.1 - 0.0009 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Sel1 PF08238.12 OAG21823.1 - 7.8e-13 48.6 14.9 0.00013 22.5 0.3 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 OAG21823.1 - 0.52 11.1 3.2 51 4.8 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1776 PF08643.10 OAG21824.1 - 1.2e-88 297.4 0.0 1.6e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAG21824.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CAP_N PF01213.19 OAG21824.1 - 0.071 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short_C2 PF13561.6 OAG21824.1 - 0.077 12.5 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase WLM PF08325.10 OAG21825.1 - 6.9e-57 192.6 1.3 9.5e-57 192.2 1.3 1.2 1 0 0 1 1 1 1 WLM domain DZR PF12773.7 OAG21825.1 - 3.5e-05 23.7 0.4 0.00013 22.0 0.4 1.9 1 1 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 OAG21825.1 - 7.1e-05 22.0 0.3 7.1e-05 22.0 0.3 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others Zincin_1 PF06262.11 OAG21825.1 - 0.2 11.8 0.1 0.92 9.7 0.1 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase zf-Sec23_Sec24 PF04810.15 OAG21825.1 - 2.2 8.4 7.4 18 5.5 0.1 2.9 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Glyco_hydro_62 PF03664.13 OAG21827.1 - 2e-58 197.9 1.0 2.5e-58 197.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DHDPS PF00701.22 OAG21830.1 - 1e-36 126.1 0.0 1.3e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.8 OAG21830.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA HET PF06985.11 OAG21832.1 - 1.7e-32 112.8 0.1 2.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pectate_lyase_3 PF12708.7 OAG21833.1 - 5.8e-63 212.6 20.1 9.3e-50 169.4 10.5 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG21833.1 - 1.4e-06 27.9 2.1 0.024 14.3 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase HemeBinding_Shp PF11545.8 OAG21833.1 - 0.012 15.6 0.2 0.039 13.9 0.2 1.9 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp F-box-like PF12937.7 OAG21835.1 - 0.0014 18.5 0.0 0.0045 16.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OAG21835.1 - 0.016 15.1 0.1 0.042 13.7 0.1 1.8 1 0 0 1 1 1 0 F-box CN_hydrolase PF00795.22 OAG21838.1 - 4.9e-27 94.9 0.0 6.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AP_endonuc_2 PF01261.24 OAG21839.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CrtC PF07143.11 OAG21840.1 - 0.0071 17.0 0.0 0.052 14.2 0.0 2.1 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain NMU PF02070.15 OAG21840.1 - 0.31 11.0 1.7 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 Neuromedin U F-box-like_2 PF13013.6 OAG21845.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain PRANC PF09372.10 OAG21845.1 - 0.21 11.9 0.0 0.33 11.3 0.0 1.2 1 0 0 1 1 1 0 PRANC domain Glyco_tranf_2_3 PF13641.6 OAG21846.1 - 4e-23 82.5 0.0 6.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG21846.1 - 7e-10 39.2 1.1 7e-10 39.2 1.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAG21846.1 - 8e-05 22.2 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG21846.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 LMBR1 PF04791.16 OAG21847.1 - 4.3e-21 75.4 17.2 9.4e-21 74.3 0.2 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF2637 PF10935.8 OAG21847.1 - 2.8 7.8 9.5 3.6 7.5 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2637) CPSF_A PF03178.15 OAG21849.1 - 1.8e-92 310.1 0.0 4.7e-92 308.7 0.0 1.8 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAG21849.1 - 3.1e-24 85.5 0.0 5.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term EPTP PF03736.17 OAG21849.1 - 0.018 15.0 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 EPTP domain CENP-B_dimeris PF09026.10 OAG21849.1 - 1.4 9.3 17.8 2 8.9 4.6 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain adh_short PF00106.25 OAG21850.1 - 7.4e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21850.1 - 2.1e-13 50.4 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG21850.1 - 1.4e-05 25.1 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG21850.1 - 0.0013 18.6 0.3 0.0018 18.2 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG21850.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_1 PF00561.20 OAG21851.1 - 2.1e-21 76.7 0.1 1.8e-20 73.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG21851.1 - 3.5e-16 60.5 0.6 7.5e-16 59.4 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG21851.1 - 2.6e-05 23.6 0.0 0.0035 16.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG21851.1 - 0.038 13.7 0.0 0.34 10.5 0.0 2.2 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Chlorophyllase PF07224.11 OAG21851.1 - 0.05 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 OAG21851.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 OAG21851.1 - 0.19 10.4 0.0 5.9 5.5 0.0 2.1 2 0 0 2 2 2 0 Ndr family CHU_C PF13585.6 OAG21854.1 - 0.021 14.9 0.4 0.021 14.9 0.4 1.7 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Helo_like_N PF17111.5 OAG21855.1 - 1.9e-11 43.7 1.1 2.5e-11 43.4 1.1 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAG21855.1 - 3e-05 24.2 0.8 4e-05 23.8 0.8 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 OAG21856.1 - 2.3e-16 60.1 2.6 2e-08 34.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG21856.1 - 7.9e-09 35.9 0.2 7.2e-07 29.6 0.1 3.1 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG21856.1 - 2.1e-08 34.2 0.1 1.3e-05 25.4 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG21856.1 - 1.1e-06 28.8 0.4 0.00012 22.3 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat NACHT PF05729.12 OAG21856.1 - 1.9e-06 27.9 0.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Ank_3 PF13606.6 OAG21856.1 - 1.3e-05 25.1 0.1 0.011 16.2 0.1 3.6 4 0 0 4 4 2 1 Ankyrin repeat AAA_22 PF13401.6 OAG21856.1 - 0.00073 19.8 0.0 0.0053 17.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG21856.1 - 0.0012 19.3 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG21856.1 - 0.0029 18.0 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OAG21856.1 - 0.0034 16.8 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_11 PF13086.6 OAG21856.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG21856.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OAG21856.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 OAG21856.1 - 0.11 11.8 0.1 1.7 7.8 0.1 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 OAG21856.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG21856.1 - 0.18 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DnaJ_C PF01556.18 OAG21857.1 - 1.4e-39 135.6 0.2 1.8e-39 135.2 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG21857.1 - 5.5e-25 87.3 0.7 9e-25 86.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG21857.1 - 2.1e-16 60.0 17.5 4.2e-16 59.1 17.5 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF1356 PF07092.12 OAG21857.1 - 0.21 10.8 2.4 1.9 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zinc_ribbon_9 PF14369.6 OAG21857.1 - 0.54 10.6 2.8 36 4.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 OAG21857.1 - 0.74 9.9 9.3 0.45 10.5 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 OAG21857.1 - 0.93 9.5 4.2 6.7 6.7 1.6 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Anti-TRAP PF15777.5 OAG21857.1 - 1.2 9.1 15.1 0.58 10.2 2.1 2.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 OAG21857.1 - 2.1 8.4 8.7 84 3.3 8.6 2.5 1 1 0 1 1 1 0 zinc-ribbons DUF2614 PF11023.8 OAG21857.1 - 2.6 8.2 7.1 4.1 7.5 0.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 OAG21857.1 - 4.7 7.3 8.0 8 6.5 1.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ABC2_membrane PF01061.24 OAG21859.1 - 2.5e-80 268.9 62.3 1.5e-41 142.2 29.2 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG21859.1 - 1.1e-35 123.2 0.2 5.7e-17 62.5 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAG21859.1 - 3.1e-31 107.1 14.6 1.1e-27 95.7 0.2 3.8 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG21859.1 - 5.1e-11 43.0 0.0 1.2e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 OAG21859.1 - 2.9e-07 30.2 0.0 0.00011 21.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG21859.1 - 6.8e-07 29.6 0.1 0.0032 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG21859.1 - 1.7e-06 28.5 0.4 0.0011 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG21859.1 - 2e-05 24.5 0.1 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG21859.1 - 0.00011 21.9 0.3 0.046 13.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG21859.1 - 0.00045 20.8 0.0 0.0055 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 OAG21859.1 - 0.0015 17.7 15.2 0.0015 17.7 15.2 4.1 3 1 0 3 3 3 1 ABC-2 family transporter protein cobW PF02492.19 OAG21859.1 - 0.002 17.8 0.4 0.053 13.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 OAG21859.1 - 0.0055 16.2 0.0 2.3 7.6 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG21859.1 - 0.0056 16.5 0.0 1.2 8.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG21859.1 - 0.015 15.0 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAG21859.1 - 0.025 14.7 0.0 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG21859.1 - 0.044 14.1 1.0 2.1 8.7 0.1 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 OAG21859.1 - 0.047 13.6 1.3 2.2 8.2 0.2 2.5 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 OAG21859.1 - 0.13 11.6 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 OAG21859.1 - 0.14 12.6 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG21859.1 - 0.22 11.9 0.9 2 8.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain URO-D PF01208.17 OAG21860.1 - 5.7e-129 430.2 0.0 6.3e-129 430.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) MutS_V PF00488.21 OAG21861.1 - 8.6e-67 224.8 0.0 1.7e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG21861.1 - 1.4e-41 142.9 4.8 3.5e-41 141.6 4.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG21861.1 - 4.6e-20 72.0 0.0 1.1e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAG21861.1 - 9.1e-10 39.0 0.0 1.3e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 OAG21861.1 - 0.0087 15.7 0.1 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAG21861.1 - 0.031 14.8 1.8 0.56 10.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG21861.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SnoaL_2 PF12680.7 OAG21862.1 - 3.6e-07 30.8 0.1 8.1e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG21862.1 - 7.4e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Zn_clus PF00172.18 OAG21863.1 - 9.4e-08 32.1 8.1 1.6e-07 31.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG21863.1 - 0.0011 17.8 0.2 0.0016 17.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1616 PF07760.11 OAG21863.1 - 0.023 14.1 0.1 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) RTA1 PF04479.13 OAG21864.1 - 2.9e-72 242.6 12.2 2.9e-72 242.6 12.2 2.0 1 1 1 2 2 2 1 RTA1 like protein DUF2644 PF10841.8 OAG21864.1 - 0.049 13.9 2.7 1.5 9.1 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) RTA1 PF04479.13 OAG21867.1 - 9.3e-30 103.8 3.7 9.3e-30 103.8 3.7 1.8 1 1 1 2 2 2 1 RTA1 like protein RTA1 PF04479.13 OAG21868.1 - 1.5e-73 246.9 4.6 1.5e-73 246.9 4.6 1.5 2 0 0 2 2 2 1 RTA1 like protein stn_TNFRSF12A PF12191.8 OAG21868.1 - 0.0011 19.2 0.4 0.0027 17.9 0.4 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1980 PF09323.10 OAG21868.1 - 8.6 6.2 5.6 3.1 7.7 0.7 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) DUF2569 PF10754.9 OAG21868.1 - 9.4 6.7 10.9 2.7 8.5 1.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Zn_clus PF00172.18 OAG21870.1 - 4.3e-09 36.3 9.7 7.7e-09 35.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG21870.1 - 0.0053 15.6 0.2 0.0053 15.6 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ALS2CR11 PF15729.5 OAG21870.1 - 0.057 12.6 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Opy2 PF09463.10 OAG21870.1 - 9.2 6.7 8.4 0.66 10.3 2.0 2.3 3 0 0 3 3 3 0 Opy2 protein Dna2 PF08696.11 OAG21871.1 - 2.3e-71 239.8 0.1 3.9e-71 239.1 0.1 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 Cas_Cas4 PF01930.17 OAG21871.1 - 3.1e-06 27.4 0.0 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF83 Csa1 PF06023.12 OAG21871.1 - 0.0039 16.6 0.5 0.0067 15.8 0.0 1.5 2 0 0 2 2 2 1 CRISPR-associated exonuclease Csa1 Mito_carr PF00153.27 OAG21872.1 - 4.6e-68 225.2 1.1 3.9e-24 84.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG21872.1 - 0.06 12.5 2.0 6.1 5.9 0.0 3.3 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Tim17 PF02466.19 OAG21872.1 - 0.57 10.6 4.4 0.39 11.1 1.4 2.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Inhibitor_I78 PF11720.8 OAG21873.1 - 1.4e-09 37.9 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 OAG21873.1 - 0.00031 21.4 0.0 0.00041 21.0 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family FTP PF07504.13 OAG21873.1 - 0.085 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif RIC1 PF07064.13 OAG21875.1 - 8.9e-96 320.1 0.1 1.2e-95 319.7 0.1 1.2 1 0 0 1 1 1 1 RIC1 RNA_pol_Rpc4 PF05132.14 OAG21875.1 - 0.1 13.1 0.3 0.17 12.3 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPL PF08144.11 OAG21877.1 - 9.2e-21 74.7 0.0 2.1e-19 70.3 0.0 3.0 3 0 0 3 3 3 1 CPL (NUC119) domain DUF3605 PF12239.8 OAG21878.1 - 8.6e-53 178.8 1.3 1e-52 178.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MFS_1 PF07690.16 OAG21879.1 - 1.6e-40 139.1 37.1 1.6e-40 139.1 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAG21881.1 - 4.6e-69 232.7 0.0 9.2e-69 231.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21881.1 - 1e-37 129.8 0.0 1.8e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG21881.1 - 7.5e-06 25.5 0.0 2.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG21881.1 - 0.00015 20.7 0.0 0.00046 19.1 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG21881.1 - 0.00025 21.0 0.0 0.0007 19.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG21881.1 - 0.0023 17.0 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OAG21881.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FtsX_ECD PF18075.1 OAG21881.1 - 0.014 16.0 0.2 0.26 11.9 0.0 2.8 2 0 0 2 2 2 0 FtsX extracellular domain Cauli_AT PF03233.13 OAG21883.1 - 0.006 16.5 0.2 0.0066 16.4 0.2 1.1 1 0 0 1 1 1 1 Aphid transmission protein tRNA_synt_2f PF02092.17 OAG21883.1 - 0.018 14.0 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit YlqD PF11068.8 OAG21883.1 - 0.019 15.3 0.3 0.024 15.0 0.3 1.1 1 0 0 1 1 1 0 YlqD protein TPD52 PF04201.15 OAG21883.1 - 0.043 13.4 0.5 0.063 12.9 0.3 1.5 1 1 0 1 1 1 0 Tumour protein D52 family PCRF PF03462.18 OAG21883.1 - 0.048 13.5 0.6 0.055 13.3 0.6 1.1 1 0 0 1 1 1 0 PCRF domain DUF4446 PF14584.6 OAG21883.1 - 0.069 13.1 0.9 0.097 12.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FlbT PF07378.11 OAG21883.1 - 0.074 13.1 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Flagellar protein FlbT DUF4525 PF15027.6 OAG21883.1 - 0.12 12.1 0.1 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DivIC PF04977.15 OAG21883.1 - 0.83 9.5 4.9 2.3 8.1 0.5 2.2 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 OAG21883.1 - 1.5 9.3 6.5 2.8 8.4 6.5 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Glyco_hydro_62 PF03664.13 OAG21884.1 - 2.7e-156 518.8 15.3 3.1e-156 518.7 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Haem_oxygenas_2 PF14518.6 OAG21885.1 - 1e-44 152.4 1.1 1e-44 152.4 1.1 1.8 2 0 0 2 2 2 1 Iron-containing redox enzyme DUF3050 PF11251.8 OAG21885.1 - 0.075 12.7 0.1 1.6 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3050) 4PPT_N PF17837.1 OAG21885.1 - 0.11 12.6 0.2 0.37 11.0 0.2 1.9 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain MTS PF05175.14 OAG21886.1 - 9.5e-14 51.3 0.0 3.6e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OAG21886.1 - 6.2e-08 32.6 0.0 9.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21886.1 - 1.1e-07 32.5 0.0 3.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAG21886.1 - 1.2e-05 25.1 0.1 5.8e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 OAG21886.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 N-6 DNA Methylase PrmA PF06325.13 OAG21886.1 - 2.4e-05 23.9 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAG21886.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 OAG21886.1 - 0.0019 17.7 0.1 0.0064 16.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAG21886.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG21886.1 - 0.0029 18.2 0.0 0.0097 16.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21886.1 - 0.0064 16.3 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG21886.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 OAG21886.1 - 0.1 13.3 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Phosphoesterase PF04185.14 OAG21887.1 - 1.4e-36 126.4 2.5 6e-36 124.4 2.0 2.1 1 1 1 2 2 2 1 Phosphoesterase family Sulfatase PF00884.23 OAG21887.1 - 0.00035 20.1 0.7 0.00062 19.3 0.7 1.4 1 1 0 1 1 1 1 Sulfatase Cu-oxidase_3 PF07732.15 OAG21888.1 - 2.5e-45 153.3 2.0 2.5e-45 153.3 2.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG21888.1 - 6.8e-41 139.2 8.5 2.6e-36 124.4 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG21888.1 - 2e-27 96.2 0.0 4.8e-26 91.8 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase DUF4834 PF16118.5 OAG21889.1 - 0.11 13.4 1.8 0.13 13.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Anoctamin PF04547.12 OAG21889.1 - 0.41 9.4 3.1 0.66 8.7 3.1 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel SUIM_assoc PF16619.5 OAG21889.1 - 0.71 10.0 7.4 9.7 6.3 7.4 2.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Porph_ging PF09697.10 OAG21889.1 - 2.7 8.6 5.5 1 9.9 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) Methyltransf_12 PF08242.12 OAG21890.1 - 2.9e-05 24.7 0.0 6.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG21890.1 - 5.2e-05 23.1 0.0 6.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG21890.1 - 0.00043 20.9 0.0 0.00072 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG21890.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 OAG21891.1 - 3.7e-09 36.7 0.1 7.1e-09 35.8 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain GST_C_3 PF14497.6 OAG21892.1 - 3.2e-08 33.6 0.1 5.3e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG21892.1 - 9.9e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG21892.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG21892.1 - 0.00014 22.2 0.1 0.00056 20.3 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAG21892.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UBD PF16455.5 OAG21894.1 - 6.7e-28 97.0 0.1 1.1e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain DUF2407 PF10302.9 OAG21894.1 - 0.013 16.1 0.2 0.03 14.9 0.2 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG21894.1 - 0.043 13.6 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 OAG21894.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Aldo_ket_red PF00248.21 OAG21895.1 - 8.2e-49 166.4 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2291 PF10054.9 OAG21895.1 - 0.086 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) PH_6 PF15406.6 OAG21896.1 - 2.4e-31 108.3 3.3 5e-31 107.3 1.9 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OAG21896.1 - 0.0051 17.3 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 PH domain ATP_bind_3 PF01171.20 OAG21897.1 - 6e-42 143.5 0.0 1.2e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 OAG21897.1 - 0.012 15.3 0.2 0.07 12.8 0.0 2.2 2 0 0 2 2 2 0 Asparagine synthase EF-hand_like PF09279.11 OAG21897.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Cpn10 PF00166.21 OAG21898.1 - 3.2e-26 91.2 0.0 3.6e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Het-C PF07217.11 OAG21899.1 - 4.6e-242 804.5 0.0 5.8e-242 804.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Condensin2nSMC PF12422.8 OAG21899.1 - 0.034 14.3 0.0 11 6.2 0.0 2.2 1 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit WH2 PF02205.20 OAG21900.1 - 7.8e-10 38.3 0.4 7.8e-10 38.3 0.4 1.9 2 0 0 2 2 2 1 WH2 motif SLAC1 PF03595.17 OAG21901.1 - 5.1e-61 206.7 52.9 5.8e-61 206.5 52.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ABC2_membrane PF01061.24 OAG21902.1 - 2.6e-80 268.8 58.5 1e-42 145.9 22.8 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG21902.1 - 3.9e-33 114.9 0.0 4.4e-16 59.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 OAG21902.1 - 6.4e-32 109.3 7.1 2.9e-29 100.8 0.1 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG21902.1 - 1.9e-13 50.8 0.4 1.9e-13 50.8 0.4 2.3 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG21902.1 - 4.8e-06 25.9 16.9 4.8e-06 25.9 16.9 2.8 2 1 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OAG21902.1 - 2.8e-05 24.1 0.1 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAG21902.1 - 4.5e-05 23.9 0.1 0.093 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 OAG21902.1 - 7.1e-05 23.4 0.0 0.038 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG21902.1 - 0.00011 22.4 0.0 0.098 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG21902.1 - 0.00024 21.0 0.0 0.65 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG21902.1 - 0.00049 19.8 0.9 0.041 13.6 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG21902.1 - 0.00089 18.9 0.5 0.0054 16.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG21902.1 - 0.0043 16.5 0.0 2.1 7.7 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OAG21902.1 - 0.0047 17.3 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAG21902.1 - 0.007 16.6 0.2 5.1 7.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG21902.1 - 0.0092 16.4 1.5 6.3 7.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAG21902.1 - 0.022 15.0 3.5 3 8.1 0.3 3.9 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 OAG21902.1 - 0.04 13.5 1.0 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAG21902.1 - 0.047 13.6 1.9 5.2 7.0 0.5 2.6 2 0 0 2 2 2 0 NACHT domain DUF872 PF05915.12 OAG21902.1 - 0.095 12.9 1.4 0.91 9.7 0.1 2.8 3 0 0 3 3 2 0 Eukaryotic protein of unknown function (DUF872) AAA_30 PF13604.6 OAG21902.1 - 0.098 12.4 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 OAG21902.1 - 0.1 12.5 0.0 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 OAG21902.1 - 0.13 12.4 0.0 38 4.4 0.1 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_13 PF13166.6 OAG21902.1 - 0.23 10.1 0.1 26 3.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain SPC25 PF06703.11 OAG21902.1 - 3.3 7.5 7.8 3.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3671 PF12420.8 OAG21902.1 - 4.6 7.3 8.9 4.1 7.5 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function APCDDC PF14921.6 OAG21903.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 adh_short PF00106.25 OAG21904.1 - 3.6e-21 75.5 0.1 4.6e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21904.1 - 1e-16 61.2 0.1 1.4e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG21904.1 - 1.2e-06 28.5 0.3 1.8e-06 28.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG21904.1 - 0.00016 20.9 0.0 0.0002 20.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GspL_C PF12693.7 OAG21905.1 - 0.13 12.1 1.2 0.21 11.4 0.2 1.8 2 0 0 2 2 2 0 GspL periplasmic domain Linocin_M18 PF04454.12 OAG21907.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 1 0 1 1 1 0 Encapsulating protein for peroxidase DUF3638 PF12340.8 OAG21908.1 - 5.2e-91 304.0 1.5 5.2e-91 304.0 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG21908.1 - 1.9e-17 62.3 0.4 4.5e-17 61.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) HECW1_helix PF18436.1 OAG21908.1 - 0.092 12.9 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 IL32 PF15225.6 OAG21908.1 - 0.12 12.8 0.3 0.5 10.7 0.3 2.1 1 0 0 1 1 1 0 Interleukin 32 Pectate_lyase PF03211.13 OAG21909.1 - 1.1e-84 283.0 7.3 1.4e-84 282.7 7.3 1.0 1 0 0 1 1 1 1 Pectate lyase RXT2_N PF08595.11 OAG21911.1 - 8.8e-27 94.0 0.1 8.8e-27 94.0 0.1 3.7 4 2 2 6 6 6 1 RXT2-like, N-terminal Syntaxin_2 PF14523.6 OAG21911.1 - 0.15 12.5 4.6 0.41 11.0 4.6 1.7 1 0 0 1 1 1 0 Syntaxin-like protein ZapB PF06005.12 OAG21911.1 - 1.3 9.5 10.2 0.57 10.7 6.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 OAG21911.1 - 2.3 8.9 10.9 0.15 12.8 4.2 2.4 3 0 0 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 OAG21911.1 - 3.2 7.6 11.3 8.4 6.2 5.9 3.1 2 1 1 3 3 3 0 Septum formation initiator Gryzun PF07919.12 OAG21912.1 - 1.3e-211 704.5 0.0 1.5e-211 704.2 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAG21912.1 - 5.6e-94 314.5 0.5 4.1e-86 288.8 1.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 NolB PF17398.2 OAG21913.1 - 0.03 14.7 0.2 0.16 12.4 0.1 2.3 2 0 0 2 2 2 0 Nodulation protein NolB Mito_carr PF00153.27 OAG21915.1 - 4.7e-49 164.3 3.8 5.2e-18 64.7 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein SPO11_like PF03533.14 OAG21915.1 - 0.55 10.4 7.4 0.093 12.8 2.8 2.0 2 0 0 2 2 2 0 SPO11 homologue DUF1604 PF07713.13 OAG21916.1 - 6.2e-41 138.1 1.8 1.9e-40 136.5 1.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAG21916.1 - 0.00054 19.8 0.2 0.0016 18.3 0.2 1.9 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.25 OAG21917.1 - 1.4e-71 241.0 0.0 2.1e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21917.1 - 2.3e-40 138.5 0.1 5.5e-40 137.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAG21917.1 - 5.6e-18 64.5 0.1 1.1e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OAG21917.1 - 2.9e-06 26.8 0.0 3.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG21917.1 - 2.3e-05 23.5 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG21917.1 - 0.00026 20.4 0.1 0.00051 19.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG21917.1 - 0.0075 16.2 0.0 0.029 14.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OAG21917.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OAG21917.1 - 0.074 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Rcd1 PF04078.13 OAG21918.1 - 1.8e-126 420.7 3.7 2.2e-126 420.4 3.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 OAG21918.1 - 1.8 8.5 20.2 2.2 8.2 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vac7 PF12751.7 OAG21918.1 - 2.7 7.4 5.2 3.7 6.9 5.2 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Ribosomal_L1 PF00687.21 OAG21919.1 - 2.7e-47 161.2 0.3 3.1e-47 161.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 OAG21919.1 - 0.074 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DUF3671 PF12420.8 OAG21919.1 - 0.9 9.6 6.5 6 7.0 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function Cid2 PF09774.9 OAG21920.1 - 5.5e-54 182.9 0.0 6.5e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DNA_ligase_A_M PF01068.21 OAG21921.1 - 7.7e-61 205.3 0.9 1.3e-57 194.7 0.9 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG21921.1 - 2.2e-43 148.6 0.0 4e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAG21921.1 - 1e-28 99.8 0.8 5.6e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OAG21921.1 - 3.1e-07 30.8 0.4 5.2e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 RNA ligase Tim54 PF11711.8 OAG21923.1 - 1.5e-149 497.9 0.1 1.7e-149 497.7 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SKA1 PF07160.12 OAG21923.1 - 0.69 9.7 4.2 1.4 8.7 4.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TPR_1 PF00515.28 OAG21924.1 - 3.6e-13 48.7 4.4 9.9e-05 22.0 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG21924.1 - 7.6e-11 41.3 4.2 0.0043 17.1 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG21924.1 - 2.7e-07 30.2 5.2 1.6e-05 24.5 0.5 2.8 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 OAG21924.1 - 7.2e-07 29.7 4.7 8.6e-05 23.1 1.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG21924.1 - 3.9e-06 26.9 0.5 0.092 13.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG21924.1 - 6.2e-06 26.0 4.8 0.28 11.5 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 OAG21924.1 - 2.6e-05 24.1 15.6 0.00021 21.1 10.1 2.4 2 0 0 2 2 2 1 STI1 domain TPR_19 PF14559.6 OAG21924.1 - 0.00019 21.9 1.4 0.15 12.6 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG21924.1 - 0.00054 20.2 2.6 0.0034 17.6 0.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG21924.1 - 0.00074 20.1 2.2 0.37 11.7 0.4 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 OAG21924.1 - 0.034 14.6 0.3 0.062 13.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 OAG21924.1 - 0.043 13.8 0.2 3.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAG21924.1 - 0.046 12.9 0.2 0.16 11.1 0.2 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG21924.1 - 0.2 11.6 4.3 0.34 10.9 0.5 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 OAG21924.1 - 0.22 11.5 4.2 2.6 8.0 2.5 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain TPR_6 PF13174.6 OAG21924.1 - 0.33 11.7 3.4 15 6.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 OAG21924.1 - 0.5 10.1 9.3 0.15 11.8 5.7 2.0 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.18 OAG21924.1 - 0.78 9.9 2.9 4.7 7.4 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pre-PUA PF17832.1 OAG21925.1 - 2.1e-25 89.2 0.4 3.2e-25 88.6 0.4 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAG21925.1 - 3.4e-16 59.0 0.0 1.2e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 OAG21925.1 - 0.016 15.5 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) HET PF06985.11 OAG21926.1 - 4.9e-23 82.1 0.1 7.7e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_N_3 PF13417.6 OAG21927.1 - 5.6e-20 71.5 0.0 1.2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG21927.1 - 4.1e-16 59.1 0.1 1e-15 57.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG21927.1 - 4.1e-07 30.2 0.0 8.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG21927.1 - 9.2e-07 28.8 0.1 2.5e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG21927.1 - 0.00078 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG21927.1 - 0.061 14.1 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2944 PF11161.8 OAG21927.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) GST_C PF00043.25 OAG21927.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG21927.1 - 0.13 12.5 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAG21927.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin JAB PF01398.21 OAG21928.1 - 0.0021 18.0 0.1 0.023 14.7 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease adh_short_C2 PF13561.6 OAG21930.1 - 2.1e-43 148.6 0.0 2.3e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG21930.1 - 4.8e-29 101.2 0.0 6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG21930.1 - 7.5e-05 22.7 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Dodecin PF07311.12 OAG21930.1 - 0.065 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Dodecin Epimerase PF01370.21 OAG21932.1 - 1.3e-18 67.3 0.2 4.2e-18 65.7 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG21932.1 - 5.2e-16 58.5 0.0 1.7e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG21932.1 - 6.2e-14 52.1 0.1 2.1e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG21932.1 - 9.8e-11 41.3 0.1 2.8e-09 36.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG21932.1 - 5.1e-09 36.3 0.2 9.3e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG21932.1 - 3.5e-08 32.9 0.0 5.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG21932.1 - 1.9e-06 27.6 0.1 5.6e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 OAG21932.1 - 0.00051 19.6 0.3 0.02 14.4 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG21932.1 - 0.006 16.5 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.17 OAG21932.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain TauD PF02668.16 OAG21933.1 - 2.7e-41 142.1 0.0 3.8e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NmrA PF05368.13 OAG21934.1 - 2e-44 151.9 0.0 2.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG21934.1 - 3.1e-13 50.0 0.1 4.1e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OAG21934.1 - 1.6e-05 25.1 0.1 2.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 OAG21934.1 - 4.1e-05 23.2 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG21934.1 - 0.002 18.0 0.1 0.0031 17.5 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAG21934.1 - 0.0023 18.5 0.2 0.0023 18.5 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 OAG21934.1 - 0.0033 16.9 0.5 0.0046 16.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG21934.1 - 0.016 14.3 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 OAG21934.1 - 0.026 13.9 1.7 0.068 12.6 1.0 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Sacchrp_dh_NADP PF03435.18 OAG21934.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 OAG21936.1 - 3.8e-10 39.7 11.2 9.1e-10 38.5 11.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimerisation PF08100.11 OAG21937.1 - 0.091 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_2 PF00891.18 OAG21938.1 - 3.1e-19 69.1 0.0 3.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG21938.1 - 0.00012 22.7 0.0 0.00068 20.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG21938.1 - 0.0036 17.1 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG21938.1 - 0.063 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TauD PF02668.16 OAG21939.1 - 3.8e-19 69.5 3.1 1.6e-18 67.5 3.1 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EHD_N PF16880.5 OAG21939.1 - 0.19 11.6 0.3 0.47 10.4 0.3 1.7 1 0 0 1 1 1 0 N-terminal EH-domain containing protein MyTH4 PF00784.17 OAG21939.1 - 0.23 12.0 0.1 0.4 11.2 0.1 1.3 1 0 0 1 1 1 0 MyTH4 domain Aa_trans PF01490.18 OAG21940.1 - 6.7e-50 170.0 34.6 7.6e-50 169.8 34.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein KR PF08659.10 OAG21941.1 - 1.2e-16 61.2 0.1 1.5e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 KR domain UbiA PF01040.18 OAG21942.1 - 3.4e-30 105.2 15.4 4.5e-30 104.8 15.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2919 PF11143.8 OAG21942.1 - 0.19 12.0 2.4 0.24 11.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) K_oxygenase PF13434.6 OAG21943.1 - 4.3e-06 26.1 0.0 2.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG21943.1 - 0.0001 21.7 0.0 0.13 11.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG21943.1 - 0.00012 22.2 0.3 0.00034 20.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 OAG21943.1 - 0.013 14.9 0.0 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG21943.1 - 0.013 14.7 0.9 0.86 8.8 0.7 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG21943.1 - 0.036 14.0 0.9 2.2 8.2 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG21943.1 - 0.04 13.2 0.6 0.53 9.5 1.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2_4 PF13894.6 OAG21944.1 - 0.33 11.9 8.5 6 8.0 2.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Aminotran_5 PF00266.19 OAG21945.1 - 1e-24 87.2 0.0 1.5e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Rad51 PF08423.11 OAG21945.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad51 zf-C2H2 PF00096.26 OAG21946.1 - 0.025 15.0 5.4 0.033 14.7 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 OAG21947.1 - 0.062 13.8 0.8 0.062 13.8 0.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG21948.1 - 0.00046 20.8 3.4 0.076 13.9 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 OAG21948.1 - 0.0078 16.2 0.4 0.17 12.0 0.0 2.5 2 0 0 2 2 2 1 BED zinc finger zf-H2C2_5 PF13909.6 OAG21948.1 - 0.09 12.6 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OAG21948.1 - 0.25 11.8 1.5 21 5.8 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAG21948.1 - 0.86 9.7 3.3 24 5.1 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG21948.1 - 1.9 9.1 8.4 8.3 7.1 0.4 3.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type Hamartin PF04388.12 OAG21949.1 - 2.3 6.8 8.4 2.7 6.6 8.4 1.0 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 OAG21951.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 OAG21952.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 PRANC domain SprT-like PF10263.9 OAG21953.1 - 1.5e-21 76.3 0.0 3.1e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 SprT-like family zf_UBZ PF18439.1 OAG21953.1 - 0.047 13.3 0.2 0.089 12.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 OAG21953.1 - 0.06 13.7 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TRAF6_Z2 PF18048.1 OAG21953.1 - 3.8 7.7 5.6 25 5.1 0.0 3.6 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 RabGAP-TBC PF00566.18 OAG21954.1 - 1.1e-47 162.4 0.1 1.8e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YdfA_immunity PF12127.8 OAG21954.1 - 0.94 8.5 3.4 1.9 7.4 3.4 1.4 1 0 0 1 1 1 0 SigmaW regulon antibacterial Homeobox_KN PF05920.11 OAG21955.1 - 1.4e-13 50.5 0.7 6.6e-13 48.3 0.9 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OAG21955.1 - 7.5e-07 28.9 0.3 2.2e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 OAG21955.1 - 3.4e-05 23.8 0.8 0.15 12.1 0.1 3.9 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAG21955.1 - 0.00032 21.3 22.9 0.002 18.8 3.5 5.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.7 OAG21955.1 - 2.3 8.7 0.0 2.3 8.7 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG21955.1 - 2.4 8.5 7.6 2.8 8.3 1.6 3.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAG21955.1 - 7.9 6.9 8.5 21 5.5 0.1 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) MFS_1 PF07690.16 OAG21956.1 - 2.7e-14 52.9 58.0 9.2e-11 41.3 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG21956.1 - 7.3e-09 35.4 7.7 1e-08 34.9 7.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 OAG21956.1 - 0.00039 19.4 10.1 0.00062 18.7 10.1 1.2 1 0 0 1 1 1 1 MFS_1 like family OATP PF03137.20 OAG21956.1 - 0.015 13.6 3.8 0.023 13.0 3.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SNF2_N PF00176.23 OAG21958.1 - 7.6e-55 186.0 0.4 2.4e-54 184.4 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 OAG21958.1 - 2.3e-24 85.0 4.3 2.1e-15 56.4 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OAG21958.1 - 8.6e-20 71.1 0.0 2.3e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 OAG21958.1 - 3e-16 59.6 0.8 2.8e-15 56.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 OAG21958.1 - 4.1e-06 26.9 0.0 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 OAG21958.1 - 0.021 15.1 22.4 0.068 13.5 0.1 5.3 3 1 1 4 4 4 0 Chromodomain helicase DNA-binding domain 1 AAA_22 PF13401.6 OAG21958.1 - 0.032 14.5 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain ADPrib_exo_Tox PF03496.14 OAG21958.1 - 0.083 12.2 3.0 0.4 10.0 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosyltransferase exoenzyme Zip PF02535.22 OAG21959.1 - 1.2 8.3 2.7 2.5 7.2 2.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter PBP1_TM PF14812.6 OAG21959.1 - 1.4 9.3 19.7 0.073 13.4 2.4 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3134 PF11332.8 OAG21959.1 - 2 8.8 4.6 6.6 7.1 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) BOP1NT PF08145.12 OAG21961.1 - 8.3e-104 347.1 5.8 1.3e-103 346.5 5.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAG21961.1 - 3.8e-23 81.3 0.6 3.9e-08 33.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21961.1 - 1.3e-07 31.8 0.3 0.0033 17.7 0.0 5.0 3 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1923 PF09083.10 OAG21961.1 - 0.12 12.1 1.9 0.17 11.6 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) Replicase PF03090.17 OAG21961.1 - 0.15 12.0 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Replicase family DEAD PF00270.29 OAG21962.1 - 1.6e-47 161.5 0.0 1.4e-45 155.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG21962.1 - 1e-25 90.3 0.0 2.7e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG21962.1 - 0.0004 20.4 0.0 0.0021 18.1 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Rz1 PF06085.11 OAG21962.1 - 7.7 6.3 6.6 0.38 10.5 0.1 2.3 3 0 0 3 3 3 0 Lipoprotein Rz1 precursor Sld5 PF05916.11 OAG21963.1 - 1.1e-14 54.9 0.0 1.5e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 OAG21964.1 - 3.8e-09 36.8 0.3 7.7e-09 35.8 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4543 PF15076.6 OAG21964.1 - 0.056 13.6 0.2 0.17 12.1 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) SF3a60_bindingd PF12108.8 OAG21965.1 - 0.19 11.6 4.0 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF3713 PF12506.8 OAG21965.1 - 1.5 9.2 6.8 12 6.2 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) SurA_N_3 PF13624.6 OAG21965.1 - 3.8 7.3 6.9 23 4.7 2.0 3.1 2 0 0 2 2 2 0 SurA N-terminal domain KxDL PF10241.9 OAG21965.1 - 3.9 7.8 18.3 3.1 8.1 2.0 5.0 4 1 0 4 4 4 0 Uncharacterized conserved protein kleA_kleC PF17383.2 OAG21965.1 - 7.9 6.9 8.7 0.88 9.9 0.3 3.6 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A Sugar_tr PF00083.24 OAG21966.1 - 1.5e-98 330.6 32.8 1.8e-98 330.4 32.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG21966.1 - 4.2e-25 88.4 39.0 6e-20 71.5 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pannexin_like PF12534.8 OAG21966.1 - 0.18 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ceramidase PF05875.12 OAG21967.1 - 3.9e-81 272.3 5.2 4.7e-81 272.1 5.2 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 OAG21967.1 - 0.021 14.7 2.2 0.084 12.8 2.2 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide ABC-3 PF00950.17 OAG21967.1 - 0.033 13.7 0.2 0.057 12.9 0.2 1.3 1 0 0 1 1 1 0 ABC 3 transport family NCE101 PF11654.8 OAG21967.1 - 0.047 13.4 0.4 0.36 10.6 0.4 2.2 2 0 0 2 2 2 0 Non-classical export protein 1 Phage_holin_3_6 PF07332.11 OAG21967.1 - 2.6 8.1 4.8 0.7 10.0 0.1 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Aldo_ket_red PF00248.21 OAG21968.1 - 9.3e-51 172.8 0.0 1e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 OAG21969.1 - 3e-07 30.6 7.7 1.4e-06 28.4 0.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAG21969.1 - 4.8e-07 29.6 0.6 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG21969.1 - 3.7e-06 27.1 0.5 3.7e-06 27.1 0.5 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG21969.1 - 4.6e-05 23.9 3.6 0.0016 19.1 0.4 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 OAG21969.1 - 0.00027 21.5 11.1 0.078 13.6 1.8 3.5 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 OAG21969.1 - 0.16 11.8 0.3 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OAG21969.1 - 0.17 12.2 0.7 2.1 8.7 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 OAG21969.1 - 0.28 11.3 0.8 16 5.6 0.1 2.3 1 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAG21969.1 - 9 6.2 7.6 0.71 9.7 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Lactonase PF10282.9 OAG21971.1 - 0.0011 18.4 0.0 0.083 12.1 0.0 2.8 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 OAG21971.1 - 0.0044 17.8 3.2 19 6.3 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21971.1 - 0.05 13.9 0.0 0.69 10.3 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Atrophin-1 PF03154.15 OAG21971.1 - 0.87 7.8 7.7 1.1 7.5 7.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family Mito_carr PF00153.27 OAG21972.1 - 1.9e-46 155.9 6.2 1.1e-17 63.7 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG21972.1 - 0.0066 15.6 0.6 0.11 11.7 0.1 2.2 2 0 0 2 2 2 1 Gammaproteobacterial serine protease DUF3337 PF11816.8 OAG21973.1 - 1.5e-56 190.9 0.0 3.4e-56 189.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAG21973.1 - 1.5e-16 60.5 16.6 7.9e-05 23.4 0.4 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG21973.1 - 0.0097 16.2 0.1 0.21 11.9 0.1 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG21973.1 - 0.037 12.7 0.3 0.29 9.7 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Acetyltransf_7 PF13508.7 OAG21974.1 - 1.3e-07 31.9 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG21974.1 - 1.1e-06 28.8 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG21974.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG21974.1 - 5e-05 23.4 0.1 9.4e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG21974.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein DUF2263 PF10021.9 OAG21975.1 - 9.6e-14 52.0 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAG21975.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Macro domain Pec_lyase_C PF00544.19 OAG21976.1 - 7.6e-15 55.1 9.0 5.2e-13 49.1 9.0 2.3 1 1 0 1 1 1 1 Pectate lyase Peptidase_M49 PF03571.15 OAG21977.1 - 2.1e-243 808.7 0.0 2.4e-243 808.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 OAG21977.1 - 0.14 12.3 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain F-box-like PF12937.7 OAG21978.1 - 2e-06 27.6 0.0 5.7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG21978.1 - 0.049 13.5 0.0 0.19 11.6 0.0 2.1 1 1 0 1 1 1 0 F-box domain Oxidored_FMN PF00724.20 OAG21979.1 - 3e-84 283.2 0.0 3.8e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family nsp9 PF08710.10 OAG21979.1 - 0.098 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase Syntaxin-5_N PF11416.8 OAG21979.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain MFS_1 PF07690.16 OAG21980.1 - 9.8e-48 162.9 49.5 2e-46 158.6 50.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG21980.1 - 2.8e-15 55.8 14.1 2.8e-15 55.8 14.1 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG21980.1 - 7.6e-14 51.4 11.9 7.6e-14 51.4 11.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Polysacc_deac_1 PF01522.21 OAG21981.1 - 9.6e-15 54.6 0.0 1.6e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SMBP PF16785.5 OAG21981.1 - 0.077 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Small metal-binding protein Fungal_trans PF04082.18 OAG21982.1 - 3.2e-20 72.3 0.0 6.9e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 OAG21983.1 - 1.8e-94 317.1 43.4 2.2e-94 316.8 43.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 OAG21983.1 - 1e-70 239.0 0.0 2e-70 238.0 0.0 1.5 1 1 0 1 1 1 1 Amidase DREPP PF05558.12 OAG21983.1 - 0.049 13.5 0.3 0.086 12.7 0.3 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Band_7 PF01145.25 OAG21984.1 - 1e-30 107.0 0.6 2.3e-30 105.9 0.6 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OAG21984.1 - 1e-24 86.3 1.8 2.8e-24 84.9 1.8 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 OAG21984.1 - 0.017 14.4 0.2 0.032 13.5 0.2 1.5 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 OAG21984.1 - 0.025 14.3 0.4 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 SPFH domain-Band 7 family Halogen_Hydrol PF10112.9 OAG21984.1 - 0.037 14.0 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein V-SNARE PF05008.15 OAG21984.1 - 6.5 7.2 9.8 0.14 12.5 1.1 2.6 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Abhydrolase_6 PF12697.7 OAG21985.1 - 0.00013 22.6 0.1 0.00022 21.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAG21985.1 - 0.012 15.5 0.0 0.083 12.7 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 OAG21985.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 OAG21985.1 - 0.034 13.4 0.0 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF3530 PF12048.8 OAG21985.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Glycos_transf_3 PF00591.21 OAG21987.1 - 1.8e-62 211.2 0.0 2.6e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAG21987.1 - 8.5e-11 41.5 0.0 2.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CBF PF03914.17 OAG21988.1 - 5.1e-57 192.6 1.8 9.1e-57 191.8 0.7 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 OAG21988.1 - 0.0015 18.6 0.6 0.0042 17.1 0.1 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAG21988.1 - 0.012 14.2 1.9 0.068 11.7 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region DNA_alkylation PF08713.11 OAG21988.1 - 0.022 14.5 0.9 1.5 8.5 0.4 2.5 2 0 0 2 2 2 0 DNA alkylation repair enzyme zf-C2H2 PF00096.26 OAG21990.1 - 1.2e-06 28.7 8.8 2.1e-05 24.7 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG21990.1 - 2.6e-05 24.4 2.4 2.6e-05 24.4 2.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAG21990.1 - 0.00032 20.6 0.4 0.00085 19.3 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG21990.1 - 0.0073 17.1 0.8 0.0073 17.1 0.8 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG21990.1 - 0.012 15.8 0.7 0.026 14.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG21990.1 - 0.23 11.9 0.4 0.23 11.9 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 OAG21990.1 - 0.33 11.3 1.9 0.66 10.3 0.7 2.1 2 1 0 2 2 2 0 zinc-ribbon zf-H2C2_5 PF13909.6 OAG21990.1 - 2.2 8.1 6.4 1.7 8.4 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ATP_bind_1 PF03029.17 OAG21991.1 - 4.9e-64 216.4 0.0 1.7e-62 211.4 0.0 2.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Arf PF00025.21 OAG21991.1 - 3.4e-05 23.4 0.0 0.17 11.3 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG21991.1 - 3.8e-05 23.3 0.0 0.01 15.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG21991.1 - 0.00016 21.7 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 OAG21991.1 - 0.00059 18.9 0.0 0.031 13.2 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OAG21991.1 - 0.00087 19.6 0.0 0.0028 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 OAG21991.1 - 0.001 19.3 0.0 0.27 11.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OAG21991.1 - 0.0014 18.2 0.0 0.065 12.8 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.12 OAG21991.1 - 0.0021 18.0 0.0 0.0057 16.6 0.0 1.7 2 0 0 2 2 1 1 NACHT domain SRPRB PF09439.10 OAG21991.1 - 0.0066 15.9 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG21991.1 - 0.0093 15.2 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 OAG21991.1 - 0.01 16.0 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 OAG21991.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG21991.1 - 0.012 15.2 0.0 0.93 9.1 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OAG21991.1 - 0.013 15.5 0.1 7 6.5 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Ras PF00071.22 OAG21991.1 - 0.019 14.5 0.0 4.7 6.8 0.0 2.6 3 0 0 3 3 3 0 Ras family NB-ARC PF00931.22 OAG21991.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OAG21991.1 - 0.037 14.4 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 OAG21991.1 - 0.038 13.6 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 OAG21991.1 - 0.041 14.3 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OAG21991.1 - 0.042 13.6 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OAG21991.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 OAG21991.1 - 0.057 12.9 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 1 0 Poxvirus A32 protein DUF87 PF01935.17 OAG21991.1 - 0.057 13.5 0.1 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 OAG21991.1 - 0.07 12.9 0.3 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Methyltransf_32 PF13679.6 OAG21991.1 - 0.14 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Viral_helicase1 PF01443.18 OAG21991.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CLP1_P PF16575.5 OAG21991.1 - 0.17 11.7 0.0 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 OAG21991.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 1 0 AAA domain CwfJ_C_1 PF04677.15 OAG21992.1 - 5.9e-28 97.2 0.0 6.4e-27 93.9 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAG21992.1 - 3.9e-24 85.4 0.2 3.9e-24 85.4 0.2 2.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.25 OAG21993.1 - 1.9e-57 194.6 0.3 4.3e-57 193.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG21993.1 - 2.8e-34 118.6 0.0 5.1e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAG21993.1 - 8.6e-29 99.5 9.9 5.3e-16 58.5 4.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 OAG21993.1 - 6.2e-20 70.8 32.7 1.5e-12 47.2 10.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 OAG21993.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Uds1 PF15456.6 OAG21993.1 - 1.1 9.4 7.4 0.14 12.3 0.3 2.7 3 0 0 3 3 3 0 Up-regulated During Septation YhhN PF07947.14 OAG21994.1 - 0.52 9.9 12.2 0.25 10.9 9.6 1.7 1 1 1 2 2 2 0 YhhN family GWT1 PF06423.12 OAG21994.1 - 2.4 8.3 5.5 3.5 7.8 5.0 1.5 1 1 0 1 1 1 0 GWT1 Beta-lactamase PF00144.24 OAG21995.1 - 5.4e-47 160.6 0.0 1.2e-46 159.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAG21995.1 - 0.034 13.6 0.1 0.064 12.7 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase AMP-binding PF00501.28 OAG21997.1 - 2.3e-76 257.1 0.0 3.4e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG21997.1 - 1.6e-63 214.3 0.0 7.2e-63 212.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OAG21997.1 - 1.8e-49 167.8 2.3 4.3e-49 166.6 2.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG21997.1 - 3e-39 135.0 0.8 1.9e-38 132.4 0.5 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG21997.1 - 2.5e-15 56.9 1.7 7.9e-12 45.4 1.1 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG21997.1 - 1.4e-13 50.9 0.0 1.8e-07 30.8 0.0 3.8 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG21997.1 - 6.9e-13 48.7 0.0 1.8e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAG21997.1 - 1.6e-08 33.9 0.2 1.9e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG21997.1 - 3.5e-06 27.0 0.8 0.00015 21.7 0.9 2.8 2 1 0 2 2 2 1 NAD(P)H-binding AMP-binding_C PF13193.6 OAG21997.1 - 0.00032 21.6 0.5 0.0042 18.0 0.0 3.3 4 0 0 4 4 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 OAG21997.1 - 0.00035 19.8 1.1 0.97 8.5 0.3 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG21997.1 - 0.00038 19.7 0.7 0.0092 15.1 0.0 2.9 2 1 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG21997.1 - 0.016 14.6 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 OAG21997.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_59 PF02057.15 OAG21998.1 - 2.9e-18 66.1 0.3 4.3e-18 65.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG21998.1 - 1.1e-12 48.3 2.5 2.7e-08 33.8 0.0 2.4 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 OAG21998.1 - 1.1e-08 34.5 0.5 2.7e-08 33.2 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAG21998.1 - 7.6e-08 32.5 3.1 1.3e-07 31.7 1.4 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain SYF2 PF08231.12 OAG21999.1 - 4.8e-46 157.1 14.2 4.8e-46 157.1 14.2 1.5 2 0 0 2 2 2 1 SYF2 splicing factor DUF4286 PF14114.6 OAG21999.1 - 0.64 10.5 3.3 27 5.3 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4286) ARD PF03079.14 OAG21999.1 - 2.8 8.1 6.4 0.5 10.5 0.2 2.6 1 1 2 3 3 3 0 ARD/ARD' family MWFE PF15879.5 OAG22000.1 - 4.3e-05 23.6 1.0 0.0002 21.5 0.0 2.5 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase MWFE subunit RRM_1 PF00076.22 OAG22000.1 - 0.0007 19.4 0.0 3.6 7.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRN3 PF05327.11 OAG22000.1 - 0.0095 14.5 1.3 0.012 14.2 1.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CWC25 PF12542.8 OAG22001.1 - 2.1e-21 76.7 0.8 2.1e-21 76.7 0.8 4.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAG22001.1 - 9.7e-13 48.1 14.4 9.7e-13 48.1 14.4 5.6 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4855 PF16147.5 OAG22001.1 - 0.032 13.3 0.9 0.052 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) p450 PF00067.22 OAG22003.1 - 1.6e-50 172.2 0.0 2e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BRI3BP PF14965.6 OAG22003.1 - 3.8 7.0 6.3 6.3 6.3 6.3 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 RNA_pol_3_Rpc31 PF11705.8 OAG22004.1 - 5.9 7.1 17.9 1.6 9.0 14.9 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Kin17_mid PF10357.9 OAG22005.1 - 9.9e-44 148.3 0.4 9.9e-44 148.3 0.4 1.8 1 1 1 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 OAG22005.1 - 0.00083 19.7 3.9 0.0018 18.6 3.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG22005.1 - 0.026 14.8 2.4 0.053 13.8 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAG22005.1 - 0.055 13.8 3.2 0.15 12.4 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Presenilin PF01080.17 OAG22005.1 - 6.1 5.5 6.0 8.3 5.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin adh_short PF00106.25 OAG22007.1 - 1e-34 119.7 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22007.1 - 5e-23 81.9 0.0 7.9e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22007.1 - 3.2e-15 56.5 0.2 4.3e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG22007.1 - 6.2e-06 25.9 0.3 1.1e-05 25.0 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG22007.1 - 4e-05 22.9 0.1 5.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG22007.1 - 5.4e-05 23.3 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG22007.1 - 0.0001 22.8 0.2 0.00022 21.8 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG22007.1 - 0.00014 22.1 0.5 0.00028 21.1 0.5 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OAG22007.1 - 0.0032 16.9 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 OAG22007.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAG22007.1 - 0.017 15.0 1.4 0.029 14.3 1.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding PALP PF00291.25 OAG22007.1 - 0.058 12.8 0.2 0.087 12.2 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AAA_19 PF13245.6 OAG22007.1 - 0.088 13.1 0.4 0.17 12.2 0.3 1.4 1 1 0 1 1 1 0 AAA domain AFOR_N PF02730.15 OAG22007.1 - 0.092 12.6 0.9 0.17 11.8 0.9 1.5 1 1 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain RmlD_sub_bind PF04321.17 OAG22007.1 - 0.11 11.6 0.2 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 OAG22007.1 - 0.15 11.6 0.9 0.26 10.8 0.9 1.5 1 1 0 1 1 1 0 NmrA-like family AdoHcyase_NAD PF00670.21 OAG22007.1 - 0.25 11.4 1.6 0.42 10.7 1.6 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AMP-binding PF00501.28 OAG22008.1 - 2.1e-72 244.0 0.0 2.6e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG22008.1 - 0.00024 22.0 0.0 0.00046 21.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.11 OAG22009.1 - 2.6e-23 83.0 0.0 4.3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PHD PF00628.29 OAG22010.1 - 0.49 10.3 3.1 6.8 6.7 1.1 2.3 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 OAG22010.1 - 0.64 10.1 3.0 0.46 10.6 0.8 1.8 2 0 0 2 2 2 0 Double zinc ribbon Rad60-SLD_2 PF13881.6 OAG22012.1 - 2.9e-12 46.7 0.0 5.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG22012.1 - 0.00075 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG22012.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family DUF92 PF01940.16 OAG22013.1 - 5.5e-83 278.0 10.3 7e-83 277.7 10.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 UMP1 PF05348.11 OAG22013.1 - 5.2e-40 136.3 0.0 9.4e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFS_1 PF07690.16 OAG22014.1 - 1.1e-25 90.4 68.0 1.8e-24 86.4 36.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 OAG22014.1 - 2e-12 46.4 15.2 3.8e-12 45.4 15.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DNA_pol_B_palm PF14792.6 OAG22015.1 - 1.5e-32 112.1 0.0 3.3e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OAG22015.1 - 3.2e-24 84.9 0.8 6.2e-24 83.9 0.2 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 OAG22015.1 - 7e-17 61.6 0.1 1.6e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 OAG22015.1 - 8.5e-17 60.7 0.2 2.3e-16 59.3 0.2 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda PTCB-BRCT PF12738.7 OAG22015.1 - 0.027 14.4 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain NTP_transf_2 PF01909.23 OAG22015.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain ATP-synt_10 PF05176.14 OAG22016.1 - 4.9e-79 265.2 0.0 6e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 OAG22017.1 - 9.2e-15 54.7 0.2 9.2e-15 54.7 0.2 3.5 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_M3_N PF08439.10 OAG22017.1 - 0.065 13.5 0.6 2.5 8.4 0.0 3.2 2 1 1 3 3 3 0 Oligopeptidase F Syntaxin-6_N PF09177.11 OAG22017.1 - 0.2 12.2 1.9 0.42 11.2 0.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 OAG22017.1 - 0.42 9.5 6.9 0.093 11.6 3.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4570 PF15134.6 OAG22017.1 - 1.3 9.0 5.3 1.8 8.6 3.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) APG6_N PF17675.1 OAG22017.1 - 3.5 8.1 7.5 12 6.5 4.9 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_L29 PF00831.23 OAG22018.1 - 1.3e-16 60.2 3.3 3.1e-16 59.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein GHMP_kinases_N PF00288.26 OAG22019.1 - 1.3e-13 50.9 0.4 2.6e-13 50.0 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG22019.1 - 1.2e-08 35.2 0.1 4.3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal PPR_2 PF13041.6 OAG22020.1 - 9e-42 141.1 5.4 9.9e-09 35.3 0.0 13.6 12 3 3 15 15 15 9 PPR repeat family PPR_3 PF13812.6 OAG22020.1 - 1.2e-36 124.6 0.7 0.0012 18.8 0.0 11.6 10 3 3 13 13 13 9 Pentatricopeptide repeat domain PPR PF01535.20 OAG22020.1 - 5.6e-22 76.4 21.4 0.00066 19.8 0.0 14.2 18 0 0 18 18 18 5 PPR repeat PPR_1 PF12854.7 OAG22020.1 - 2.2e-21 75.2 0.3 1.3e-06 28.0 0.0 10.1 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 OAG22020.1 - 6.9e-21 74.6 14.7 1.7e-07 30.8 0.0 6.3 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 OAG22020.1 - 5.3e-05 23.6 0.1 0.002 18.5 0.0 3.0 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 OAG22020.1 - 0.0091 15.1 0.7 4.7 6.3 0.0 4.1 6 0 0 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 OAG22020.1 - 0.61 10.2 2.7 29 5.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG22020.1 - 7.5 7.1 10.4 8.7 6.9 0.0 5.9 7 1 0 7 7 7 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 OAG22022.1 - 5e-07 29.9 15.7 2.1e-05 24.7 0.7 7.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 OAG22022.1 - 0.015 15.7 1.2 0.015 15.7 1.2 10.3 11 1 0 11 11 11 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG22022.1 - 2.8 8.3 20.3 0.24 11.7 0.8 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG22022.1 - 6.7 7.3 14.7 8.2 7.0 0.4 4.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SH3_9 PF14604.6 OAG22023.1 - 0.0001 22.1 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG22023.1 - 0.0006 19.4 0.4 0.0012 18.4 0.4 1.4 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 OAG22023.1 - 0.0009 19.8 0.1 0.0024 18.5 0.1 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CD34_antigen PF06365.12 OAG22023.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family CYYR1 PF10873.8 OAG22023.1 - 0.0026 18.2 0.3 0.0062 17.0 0.3 1.6 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 DAP10 PF07213.11 OAG22023.1 - 0.012 15.5 4.4 0.034 14.1 0.3 2.7 2 0 0 2 2 2 0 DAP10 membrane protein Adeno_E3_CR2 PF02439.15 OAG22023.1 - 0.075 12.8 1.7 0.13 12.0 1.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ESCRT-II PF05871.12 OAG22024.1 - 2.9e-49 166.9 0.0 3.5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PPR_1 PF12854.7 OAG22024.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PPR repeat PPR PF01535.20 OAG22024.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 PPR repeat Death PF00531.22 OAG22024.1 - 0.17 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Death domain Apq12 PF12716.7 OAG22025.1 - 2.2e-22 78.7 9.5 3.7e-22 78.0 9.5 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis EphA2_TM PF14575.6 OAG22026.1 - 0.053 14.4 0.0 0.094 13.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RNB PF00773.19 OAG22027.1 - 4.6e-100 335.1 0.9 7.2e-100 334.5 0.9 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 OAG22027.1 - 4.5e-31 106.7 0.2 1.4e-30 105.1 0.2 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 OAG22027.1 - 2e-28 98.9 0.1 5.4e-28 97.6 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 OAG22027.1 - 2.3e-21 75.6 0.0 6.4e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAG22027.1 - 3.8e-10 39.8 0.1 8.8e-06 25.8 0.0 3.3 2 1 1 3 3 3 2 Cold shock domain PIN_4 PF13638.6 OAG22027.1 - 1.6e-08 34.9 0.6 7.5e-07 29.5 0.1 2.8 2 0 0 2 2 2 1 PIN domain Dis3l2_C_term PF17877.1 OAG22027.1 - 0.0069 16.7 0.0 0.036 14.4 0.0 2.3 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal V-ATPase_H_N PF03224.14 OAG22028.1 - 1.6e-81 274.0 0.2 2.3e-81 273.5 0.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAG22028.1 - 9.4e-37 125.7 0.1 1.3e-35 122.1 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H DUF3829 PF12889.7 OAG22028.1 - 0.044 13.2 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Cortex-I_coil PF09304.10 OAG22028.1 - 0.21 11.8 2.8 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Cortexillin I, coiled coil CRC_subunit PF08624.10 OAG22030.1 - 1.7e-52 177.5 0.0 2.4e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 OAG22030.1 - 2.2 8.4 6.9 9.1 6.5 6.9 2.2 1 0 0 1 1 1 0 AT hook motif SF3A2 PF16835.5 OAG22031.1 - 2.6e-34 117.4 0.0 4.2e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAG22031.1 - 2e-05 24.8 0.5 2e-05 24.8 0.5 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 OAG22031.1 - 0.051 13.1 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.25 OAG22032.1 - 1.9e-18 66.2 0.1 3.2e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 OAG22032.1 - 9.4e-11 41.8 1.6 0.0032 17.8 1.3 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG22032.1 - 6e-06 25.9 5.4 0.013 15.3 2.1 4.6 2 2 2 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 OAG22032.1 - 0.0015 18.1 0.8 0.069 12.7 0.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAG22032.1 - 0.0023 17.8 4.8 3.5 7.9 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat Cupin_8 PF13621.6 OAG22033.1 - 1.3e-31 110.3 0.0 1.7e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG22033.1 - 7.5e-05 22.3 0.0 0.00023 20.8 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 OAG22033.1 - 0.00022 21.6 0.0 0.0018 18.7 0.0 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAG22033.1 - 0.0022 17.6 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 OAG22033.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3701 PF12482.8 OAG22033.1 - 0.09 12.9 1.0 0.35 11.0 0.7 2.1 2 0 0 2 2 2 0 Phage integrase protein Prefoldin PF02996.17 OAG22034.1 - 5e-23 81.3 0.0 6.5e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mating_N PF12731.7 OAG22034.1 - 0.028 14.5 0.2 0.048 13.8 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein beta 1 Prefoldin_2 PF01920.20 OAG22034.1 - 0.074 13.0 0.2 9.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Phage_TAC_11 PF11836.8 OAG22034.1 - 0.13 12.3 0.0 0.75 10.0 0.0 1.9 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 Ribosomal_L23 PF00276.20 OAG22036.1 - 1.1e-07 32.1 0.0 3.8e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Aida_N PF08910.10 OAG22036.1 - 0.15 12.5 2.6 0.18 12.2 1.7 1.6 1 1 0 1 1 1 0 Aida N-terminus AROS PF15684.5 OAG22036.1 - 0.17 12.4 5.9 0.26 11.9 5.9 1.3 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 SGL PF08450.12 OAG22039.1 - 3.7e-05 23.4 0.2 0.0015 18.1 0.1 2.6 2 2 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region ABC_tran PF00005.27 OAG22041.1 - 1.9e-46 158.0 0.5 7.2e-22 78.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG22041.1 - 2.3e-21 75.6 3.5 2.3e-21 75.6 3.5 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 OAG22041.1 - 4e-17 63.0 0.2 0.0012 18.7 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG22041.1 - 4.5e-10 39.3 0.3 0.0092 15.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG22041.1 - 2.5e-06 28.2 14.0 0.018 15.5 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 OAG22041.1 - 1.7e-05 25.1 0.1 0.15 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG22041.1 - 2.4e-05 24.1 0.3 0.0021 17.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAG22041.1 - 2.8e-05 24.1 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG22041.1 - 4.8e-05 23.4 0.3 0.087 12.9 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG22041.1 - 6.3e-05 23.5 0.1 0.63 10.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAG22041.1 - 8.6e-05 22.2 0.3 0.28 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG22041.1 - 0.00013 22.4 2.9 0.015 15.7 0.5 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 OAG22041.1 - 0.00013 22.1 0.1 0.75 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAG22041.1 - 0.00037 20.3 0.0 0.89 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG22041.1 - 0.0017 18.6 2.8 0.13 12.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG22041.1 - 0.002 18.0 0.2 0.64 9.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OAG22041.1 - 0.0021 18.5 0.1 4.1 7.8 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG22041.1 - 0.0081 16.2 0.0 3.7 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG22041.1 - 0.012 16.0 0.0 7.9 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_27 PF13514.6 OAG22041.1 - 0.014 15.0 0.2 6 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OAG22041.1 - 0.034 13.8 10.8 0.66 9.6 0.0 4.1 5 1 0 5 5 5 0 AAA ATPase domain Dynamin_N PF00350.23 OAG22041.1 - 0.04 14.0 0.3 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin family MeaB PF03308.16 OAG22041.1 - 0.047 12.7 0.3 6.2 5.7 0.0 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 OAG22041.1 - 0.053 12.8 0.1 8.7 5.6 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 OAG22041.1 - 0.067 13.1 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 OAG22041.1 - 0.082 12.9 0.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OAG22041.1 - 0.084 12.5 0.5 7.3 6.1 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OAG22041.1 - 0.11 12.5 0.3 12 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OAG22041.1 - 0.12 12.0 0.2 8.3 6.0 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 OAG22041.1 - 0.12 12.2 0.1 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AdoHcyase PF05221.17 OAG22042.1 - 2.2e-128 427.6 0.0 9.9e-74 248.2 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAG22042.1 - 1.9e-82 275.1 1.9 2.9e-82 274.5 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG22042.1 - 4.2e-07 29.5 0.1 9.6e-07 28.3 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 OAG22042.1 - 0.002 17.9 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 OAG22042.1 - 0.0022 17.6 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAG22042.1 - 0.0087 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 OAG22042.1 - 0.067 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HgmA PF04209.13 OAG22043.1 - 1.3e-200 666.6 0.1 1.5e-200 666.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 OAG22044.1 - 5.2e-52 176.7 0.0 7.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG22044.1 - 8.7e-33 112.7 0.0 1.6e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.22 OAG22045.1 - 4.9e-62 210.2 0.0 6.1e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 OAG22046.1 - 0.0006 19.3 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HET PF06985.11 OAG22047.1 - 3.6e-24 85.8 0.1 6.7e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAPEG PF01124.18 OAG22048.1 - 9.4e-16 57.9 2.5 1.2e-15 57.6 2.5 1.2 1 0 0 1 1 1 1 MAPEG family Arf PF00025.21 OAG22049.1 - 6.7e-80 266.6 0.2 7.7e-80 266.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG22049.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG22049.1 - 3.7e-14 52.5 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG22049.1 - 1.7e-13 50.5 1.2 1.6e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG22049.1 - 8.8e-13 48.2 0.0 9.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG22049.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG22049.1 - 5.1e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG22049.1 - 0.0085 15.4 0.4 0.027 13.8 0.1 1.7 1 1 0 2 2 2 1 6-phosphofructo-2-kinase Mob1_phocein PF03637.17 OAG22050.1 - 5.8e-43 146.8 0.0 1.9e-42 145.2 0.0 1.7 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 OAG22051.1 - 2.6e-40 138.0 0.5 2.6e-40 138.0 0.5 1.5 1 1 0 1 1 1 1 Leo1-like protein DUF4407 PF14362.6 OAG22051.1 - 2 7.7 5.1 3.1 7.1 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_2 PF03446.15 OAG22052.1 - 2.1e-25 89.7 0.0 3.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG22052.1 - 5.7e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG22052.1 - 0.001 19.6 0.0 0.0024 18.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG22052.1 - 0.0045 17.1 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Thr_synth_N PF14821.6 OAG22053.1 - 4.8e-30 103.6 0.0 1.3e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 OAG22053.1 - 8.5e-18 64.8 0.0 6.4e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_9 PF13527.7 OAG22054.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG22054.1 - 0.013 15.9 0.1 0.025 15.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBR PF01485.21 OAG22055.1 - 0.00082 19.5 7.2 0.00082 19.5 7.2 3.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain HORMA PF02301.18 OAG22056.1 - 5.2e-07 29.5 0.0 7.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 OAG22057.1 - 4.1e-08 33.0 1.2 3.5e-07 30.0 0.2 3.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG22057.1 - 0.00023 21.2 0.2 0.016 15.2 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein Proteasom_PSMB PF10508.9 OAG22057.1 - 0.006 15.1 0.2 1.2 7.6 0.0 2.7 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 OAG22057.1 - 0.057 13.1 0.1 0.75 9.5 0.0 2.8 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis MFS_1 PF07690.16 OAG22058.1 - 7.6e-41 140.2 37.2 3.3e-37 128.2 21.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG22058.1 - 2.6e-09 36.4 9.5 2.6e-09 36.4 9.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 OAG22058.1 - 0.00019 20.0 3.8 0.00019 20.0 3.8 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Herpes_UL73 PF03554.13 OAG22058.1 - 0.0043 17.0 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 UL73 viral envelope glycoprotein Fructosamin_kin PF03881.14 OAG22059.1 - 2.6e-36 125.3 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG22059.1 - 0.0029 17.6 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TMEM156 PF15106.6 OAG22059.1 - 0.078 12.4 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 TMEM156 protein family ANAPC4_WD40 PF12894.7 OAG22060.1 - 3.6e-08 33.6 0.0 0.55 10.6 0.0 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 OAG22060.1 - 3.2e-06 27.6 0.1 1.3e-05 25.6 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 OAG22060.1 - 8e-05 22.5 0.0 0.00038 20.2 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 OAG22060.1 - 0.00048 19.7 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG22060.1 - 0.013 16.1 0.1 0.064 13.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pneumo_att_G PF05539.11 OAG22060.1 - 0.5 9.9 2.6 0.85 9.1 2.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HET PF06985.11 OAG22062.1 - 2.8e-34 118.6 0.3 4.3e-34 118.0 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUZ PF12752.7 OAG22063.1 - 6.4e-07 30.0 5.4 6.4e-07 30.0 5.4 3.3 3 1 0 3 3 3 1 SUZ domain B3_4 PF03483.17 OAG22064.1 - 0.055 13.1 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 B3/4 domain CBFD_NFYB_HMF PF00808.23 OAG22065.1 - 2.4e-11 43.7 0.1 4.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG22065.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 2.2 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAG22065.1 - 0.003 17.7 0.2 0.0046 17.1 0.2 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIIA PF03153.13 OAG22065.1 - 0.075 13.0 12.7 0.083 12.9 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAFII28 PF04719.14 OAG22065.1 - 0.097 12.8 0.1 0.097 12.8 0.1 2.0 3 0 0 3 3 3 0 hTAFII28-like protein conserved region BUD22 PF09073.10 OAG22065.1 - 0.14 11.4 15.8 0.16 11.3 15.8 1.1 1 0 0 1 1 1 0 BUD22 CENP-X PF09415.10 OAG22065.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Arrestin_N PF00339.29 OAG22066.1 - 2e-07 31.2 0.1 6.6e-06 26.2 0.1 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_17 PF00332.18 OAG22067.1 - 8e-25 88.1 0.4 3.1e-24 86.1 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DapH_N PF08503.10 OAG22067.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Glyco_hydro_47 PF01532.20 OAG22068.1 - 1.2e-162 542.0 0.0 1.3e-162 541.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.16 OAG22069.1 - 1.2e-35 123.1 44.5 1.2e-35 123.1 44.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Svs_4_5_6 PF17381.2 OAG22069.1 - 0.14 13.1 6.0 0.32 12.0 6.0 1.5 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 Aldedh PF00171.22 OAG22070.1 - 5.5e-108 361.4 0.0 6.5e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SRP9-21 PF05486.12 OAG22070.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) GN3L_Grn1 PF08701.11 OAG22071.1 - 1.6e-24 85.8 16.5 4.6e-24 84.3 16.5 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OAG22071.1 - 2.7e-17 62.9 0.1 2.3e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG22071.1 - 1.5e-05 24.6 0.2 4.7e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG22071.1 - 1.7e-05 24.8 0.1 0.00024 21.0 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAG22071.1 - 2.5e-05 24.4 5.9 0.067 13.3 0.4 3.8 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 OAG22071.1 - 0.00073 19.1 0.3 0.22 11.1 0.1 2.9 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OAG22071.1 - 0.012 14.6 0.1 0.012 14.6 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 OAG22071.1 - 0.018 14.5 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 OAG22071.1 - 0.028 15.0 1.1 0.054 14.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OAG22071.1 - 0.085 13.1 0.1 7.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OAG22071.1 - 0.12 11.7 0.1 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 OAG22071.1 - 0.48 10.8 0.0 0.48 10.8 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain YqfQ PF14181.6 OAG22071.1 - 8.8 6.5 0.0 8.8 6.5 0.0 3.4 3 0 0 3 3 3 0 YqfQ-like protein HAD_2 PF13419.6 OAG22072.1 - 8e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG22072.1 - 7.1e-08 33.0 0.1 0.0013 19.0 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG22072.1 - 4.3e-05 24.0 0.0 6.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAG22072.1 - 0.065 13.4 0.1 0.84 9.8 0.1 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG22072.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 OAG22073.1 - 2.5e-13 49.6 0.6 7.2e-13 48.2 0.6 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG22073.1 - 0.13 12.2 1.3 0.21 11.5 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain DEAD PF00270.29 OAG22076.1 - 1.8e-46 158.1 0.0 3.4e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG22076.1 - 2.4e-24 85.8 0.0 9.9e-24 83.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG22076.1 - 2.2e-18 66.2 0.0 5.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C_2 PF13307.6 OAG22076.1 - 0.078 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.6 OAG22076.1 - 0.15 11.3 0.0 0.15 11.3 0.0 4.7 4 1 1 5 5 5 0 U3-containing 90S pre-ribosomal complex subunit DnaJ PF00226.31 OAG22077.1 - 8e-13 48.3 0.3 8e-13 48.3 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain Zn_clus PF00172.18 OAG22078.1 - 0.00036 20.6 11.6 0.00054 20.0 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 OAG22078.1 - 0.0055 16.9 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold DEAD PF00270.29 OAG22079.1 - 3.4e-49 167.0 0.1 1.2e-48 165.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG22079.1 - 6.8e-27 94.0 0.1 3.8e-25 88.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAG22079.1 - 3.1e-21 75.4 4.3 1.5e-20 73.2 4.3 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 OAG22079.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RPA_C PF08784.11 OAG22080.1 - 5.3e-20 72.0 0.2 1.8e-19 70.3 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAG22080.1 - 1.3e-08 34.7 0.1 3.6e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain MarR_2 PF12802.7 OAG22080.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 OAG22080.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 OAG22080.1 - 0.019 14.5 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FoP_duplication PF13865.6 OAG22080.1 - 0.2 12.2 5.0 0.31 11.6 0.1 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 IATP PF04568.12 OAG22080.1 - 1.2 9.6 3.7 1.1 9.7 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF202 PF02656.15 OAG22081.1 - 6.1e-16 58.6 1.8 1.6e-15 57.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NrsF PF06532.11 OAG22081.1 - 0.02 14.6 1.6 0.025 14.3 1.6 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F COX4_pro_2 PF07835.12 OAG22081.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV CIA30 PF08547.12 OAG22082.1 - 4.6e-40 137.3 0.2 6.3e-40 136.8 0.2 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Glyco_hydro_88 PF07470.13 OAG22083.1 - 1.5e-62 211.7 6.7 2.1e-62 211.2 6.7 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 OAG22084.1 - 1.6e-69 234.9 0.0 1.9e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG22085.1 - 4e-37 128.0 0.2 5.2e-37 127.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG22085.1 - 1.1e-26 93.5 0.2 1.5e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1924 PF09086.11 OAG22085.1 - 7.3e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1924) KR PF08659.10 OAG22085.1 - 0.018 15.0 0.4 0.037 14.0 0.4 1.5 1 0 0 1 1 1 0 KR domain Chlam_PMP PF02415.17 OAG22085.1 - 0.073 13.6 0.1 3.4 8.3 0.0 3.1 2 2 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Xan_ur_permease PF00860.20 OAG22086.1 - 3.7e-25 88.4 27.6 4.9e-24 84.8 27.6 2.5 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 OAG22086.1 - 0.0011 19.3 4.8 0.0011 19.3 4.8 3.0 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF2834 PF11196.8 OAG22086.1 - 0.25 11.7 4.5 1.1 9.7 4.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) DUF3488 PF11992.8 OAG22086.1 - 0.33 9.8 2.4 0.69 8.8 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Methyltransf_11 PF08241.12 OAG22087.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA_2 PF13911.6 OAG22088.1 - 1.8e-08 34.5 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OAG22088.1 - 9.6e-05 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Pyr_redox_2 PF07992.14 OAG22090.1 - 3.7e-18 65.8 0.2 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG22090.1 - 1.5e-06 27.6 0.0 8.6e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG22090.1 - 1.2e-05 24.7 0.2 0.0022 17.3 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG22090.1 - 2.6e-05 23.1 0.0 0.0004 19.2 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG22090.1 - 0.00017 20.8 0.1 0.045 12.8 0.0 2.5 1 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG22090.1 - 0.0028 17.1 0.3 0.022 14.1 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG22090.1 - 0.005 16.9 0.2 0.28 11.1 0.0 2.5 1 1 1 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG22090.1 - 0.0064 15.8 0.1 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 OAG22090.1 - 0.0083 16.3 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG22090.1 - 0.011 14.9 0.0 0.95 8.5 0.0 2.2 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG22090.1 - 0.083 12.5 0.3 0.18 11.4 0.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 OAG22092.1 - 1e-23 83.8 49.9 6.3e-17 61.5 26.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferritin_2 PF13668.6 OAG22093.1 - 1e-40 139.1 0.9 1.7e-40 138.3 0.9 1.4 1 0 0 1 1 1 1 Ferritin-like domain RNB PF00773.19 OAG22094.1 - 2.6e-92 309.7 0.0 4.2e-92 309.0 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OAG22094.1 - 1.5e-25 89.0 0.0 4.1e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 OAG22094.1 - 8.4e-25 86.9 0.0 2.9e-24 85.2 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 OAG22094.1 - 0.00029 20.9 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 OAG22094.1 - 0.0038 16.9 1.4 0.0055 16.4 0.0 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain GLE1 PF07817.13 OAG22095.1 - 7.2e-28 97.5 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein BASP1 PF05466.12 OAG22095.1 - 0.0019 18.3 45.5 0.0039 17.2 45.5 1.5 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) EphA2_TM PF14575.6 OAG22096.1 - 0.02 15.8 0.0 0.037 14.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.11 OAG22096.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SIT PF15330.6 OAG22096.1 - 0.11 13.0 0.2 0.24 11.9 0.2 1.7 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Ureide_permease PF07168.11 OAG22096.1 - 0.2 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Ureide permease PTCB-BRCT PF12738.7 OAG22097.1 - 1.5e-30 105.0 0.3 7.9e-21 73.8 0.5 4.3 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 OAG22097.1 - 2.2e-25 88.8 0.2 6.1e-09 36.1 0.1 5.4 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OAG22097.1 - 1.9e-24 85.4 0.0 2.3e-21 75.6 0.1 3.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 OAG22097.1 - 2.8e-20 72.5 0.5 0.00016 22.1 0.0 6.7 7 0 0 7 7 7 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG22097.1 - 1.1e-05 25.6 0.0 0.42 10.9 0.0 3.5 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Abhydrolase_6 PF12697.7 OAG22098.1 - 5.6e-13 50.0 0.1 9.6e-13 49.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG22098.1 - 2.8e-07 30.1 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG22098.1 - 0.0004 20.1 0.0 0.00071 19.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 OAG22098.1 - 0.013 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Chlorophyllase2 PF12740.7 OAG22098.1 - 0.039 12.9 0.0 0.1 11.5 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.13 OAG22098.1 - 0.18 11.5 0.0 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Tocopherol_cycl PF14249.6 OAG22099.1 - 1.9e-06 27.2 4.4 8.7e-06 25.1 4.0 2.3 2 1 0 2 2 2 1 Tocopherol cyclase Myb_Cef PF11831.8 OAG22101.1 - 1.3e-50 172.3 9.8 1.3e-50 172.3 9.8 3.1 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAG22101.1 - 7.4e-20 70.9 8.9 2.6e-10 40.3 1.5 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG22101.1 - 4.9e-15 55.5 7.2 1.3e-09 38.2 2.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ion_trans PF00520.31 OAG22104.1 - 2.2e-124 413.5 75.0 6.2e-41 140.2 2.0 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OAG22104.1 - 0.00044 19.9 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 OAG22104.1 - 0.0091 16.4 0.0 0.034 14.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG22104.1 - 0.0098 15.4 0.0 0.029 13.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG22104.1 - 0.056 13.4 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain DUF4079 PF13301.6 OAG22104.1 - 0.29 11.3 2.4 12 6.0 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF4079) PHD PF00628.29 OAG22105.1 - 2.8e-08 33.5 10.1 6.3e-08 32.4 10.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG22105.1 - 0.00035 20.1 3.6 0.00035 20.1 3.6 2.0 2 0 0 2 2 2 1 PHD-finger YL1 PF05764.13 OAG22105.1 - 0.0041 17.3 33.0 0.0097 16.1 33.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C1_2 PF03107.16 OAG22105.1 - 8.8 6.7 10.3 6.3 7.2 5.0 2.3 1 1 1 2 2 2 0 C1 domain LIM PF00412.22 OAG22106.1 - 1.3e-25 89.4 30.5 2.6e-09 37.2 3.9 3.7 4 0 0 4 4 4 3 LIM domain Fungal_trans PF04082.18 OAG22107.1 - 2.8e-17 62.6 0.1 5.5e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22107.1 - 6.9e-09 35.7 10.7 1.3e-08 34.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 OAG22108.1 - 1.8e-47 160.7 3.2 9.6e-47 158.3 3.5 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAG22108.1 - 1.7e-25 88.8 1.5 4.9e-25 87.3 1.5 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 OAG22110.1 - 5.4e-46 155.5 0.1 2.9e-44 149.9 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG22110.1 - 2.6e-33 114.6 0.0 4.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain BSP_II PF05432.11 OAG22110.1 - 0.0027 17.5 9.8 0.0027 17.5 9.8 2.1 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) HEPN_Toprim_N PF18871.1 OAG22110.1 - 0.11 12.4 1.8 0.18 11.7 0.0 2.2 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 Peptidase_S64 PF08192.11 OAG22110.1 - 0.42 9.0 2.4 0.64 8.4 2.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 HIT PF01230.23 OAG22111.1 - 4.4e-19 69.0 0.3 7.9e-19 68.2 0.1 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 OAG22111.1 - 1e-05 26.0 0.1 2.4e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding SPT2 PF08243.11 OAG22111.1 - 0.034 14.7 0.7 0.25 11.9 0.1 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein CwfJ_C_1 PF04677.15 OAG22111.1 - 0.15 11.9 0.2 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 TRAM_LAG1_CLN8 PF03798.16 OAG22112.1 - 1.5e-48 165.2 11.3 1.5e-48 165.2 11.3 1.4 2 0 0 2 2 2 1 TLC domain Colicin_V PF02674.16 OAG22112.1 - 4.1 7.4 10.6 0.26 11.2 0.8 2.9 3 1 0 3 3 3 0 Colicin V production protein RRM_1 PF00076.22 OAG22113.1 - 2.3e-11 43.3 0.1 3.9e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 OAG22113.1 - 0.13 12.9 4.5 0.72 10.5 1.0 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sod_Cu PF00080.20 OAG22114.1 - 2.1e-08 34.4 0.0 3.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 OAG22114.1 - 0.036 15.0 0.2 0.083 13.9 0.2 1.7 1 1 0 1 1 1 0 CHRD domain RtcB PF01139.17 OAG22115.1 - 4.2e-18 65.7 0.0 4.4e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Granulin PF00396.18 OAG22118.1 - 4 7.8 20.3 4.4 7.7 11.8 3.0 2 1 0 2 2 2 0 Granulin His_Phos_2 PF00328.22 OAG22119.1 - 1.1e-10 41.4 0.0 1.4e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Citrate_synt PF00285.21 OAG22120.1 - 2.7e-20 72.8 0.0 5.6e-17 61.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 OAG22120.1 - 1.1e-17 64.5 0.0 2.7e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 OAG22120.1 - 4e-14 52.7 0.3 7.3e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG22120.1 - 2e-06 27.7 0.0 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 OAG22121.1 - 7.9e-88 292.6 0.0 1.1e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 OAG22121.1 - 1.6e-08 34.3 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain F-box-like PF12937.7 OAG22122.1 - 6.5e-09 35.6 0.2 1.1e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG22122.1 - 1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG22122.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 F-box RNase_PH PF01138.21 OAG22123.1 - 1.5e-18 67.5 0.0 2.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG22123.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Calponin PF00402.18 OAG22123.1 - 0.13 11.9 0.8 0.26 10.9 0.8 1.5 1 0 0 1 1 1 0 Calponin family repeat MFS_1 PF07690.16 OAG22124.1 - 2.5e-12 46.4 28.9 2.5e-12 46.4 28.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG22124.1 - 4.1e-06 26.5 7.2 4.1e-06 26.5 7.2 2.3 2 1 0 2 2 2 1 Nodulin-like 7tm_7 PF08395.12 OAG22124.1 - 0.06 12.5 4.2 2.1 7.5 0.4 2.5 3 0 0 3 3 3 0 7tm Chemosensory receptor Pkinase PF00069.25 OAG22125.1 - 4.6e-31 108.1 0.0 5.8e-18 65.2 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22125.1 - 1.4e-15 57.3 0.0 4.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAG22125.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG22125.1 - 0.53 10.2 2.8 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1168 PF06658.12 OAG22126.1 - 0.86 9.4 18.5 0.42 10.4 5.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) AA_permease PF00324.21 OAG22127.1 - 3e-114 382.3 33.0 3.7e-114 382.0 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG22127.1 - 1.1e-20 73.8 37.0 1.5e-20 73.4 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease EF-hand_5 PF13202.6 OAG22129.1 - 0.00011 21.5 3.5 0.15 11.6 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OAG22129.1 - 0.00048 19.5 2.2 0.32 10.6 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OAG22129.1 - 0.00092 19.0 1.2 0.93 9.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAG22129.1 - 0.012 16.1 0.2 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Dockerin_1 PF00404.18 OAG22129.1 - 0.013 15.7 2.2 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain CPDase PF07823.11 OAG22130.1 - 3.5e-40 137.9 0.0 3.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAG22130.1 - 0.00024 21.0 0.2 0.044 13.7 0.0 2.3 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF3336 PF11815.8 OAG22131.1 - 1.5e-32 112.2 0.6 6.6e-32 110.1 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG22131.1 - 5.5e-18 65.9 0.3 1.1e-17 65.0 0.3 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase APS_kinase PF01583.20 OAG22132.1 - 3.6e-71 238.2 0.0 4.7e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAG22132.1 - 1.7e-05 25.0 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG22132.1 - 9.6e-05 22.9 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG22132.1 - 0.0016 18.0 0.0 0.0019 17.7 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 6PF2K PF01591.18 OAG22132.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_29 PF13555.6 OAG22132.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 OAG22132.1 - 0.045 12.9 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF463 PF04317.12 OAG22132.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 OAG22132.1 - 0.14 12.5 0.1 0.15 12.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain Sdh5 PF03937.16 OAG22133.1 - 0.078 13.0 0.8 0.14 12.2 0.8 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase zf-HIT PF04438.16 OAG22133.1 - 0.081 12.8 3.3 0.12 12.3 3.3 1.3 1 0 0 1 1 1 0 HIT zinc finger DENN PF02141.21 OAG22134.1 - 2.3e-41 141.8 0.1 4e-41 141.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAG22134.1 - 3.3e-06 27.7 0.0 1e-05 26.2 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.11 OAG22134.1 - 0.016 15.7 5.7 0.016 15.7 5.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MCC-bdg_PDZ PF10506.9 OAG22134.1 - 1.1 9.3 4.4 0.88 9.6 1.9 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF724 PF05266.14 OAG22134.1 - 4.2 7.2 13.2 6.1 6.6 12.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 OAG22134.1 - 6.5 7.0 16.1 0.34 11.1 4.4 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 BRE1 PF08647.11 OAG22134.1 - 8.5 6.5 20.5 1.3 9.1 8.1 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Kinesin PF00225.23 OAG22135.1 - 3.5e-90 302.3 0.0 3.5e-90 302.3 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OAG22135.1 - 1.8e-22 79.9 0.0 8.2e-17 61.5 0.0 3.9 2 1 1 3 3 3 2 Microtubule binding Atg14 PF10186.9 OAG22135.1 - 0.0041 16.3 19.6 0.0041 16.3 19.6 8.9 3 2 5 9 9 9 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3800 PF12686.7 OAG22135.1 - 0.0088 16.7 0.0 27 5.4 0.0 4.9 2 2 0 2 2 2 1 Protein of unknown function (DUF3800) HalOD1 PF18545.1 OAG22135.1 - 0.069 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Halobacterial output domain 1 AAA_24 PF13479.6 OAG22135.1 - 0.088 12.5 0.7 5.5 6.7 0.1 3.2 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 OAG22139.1 - 3e-54 184.1 0.0 4.8e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22139.1 - 1.9e-30 106.0 0.0 1.1e-29 103.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG22139.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OAG22139.1 - 0.064 12.2 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fe_hyd_lg_C PF02906.14 OAG22140.1 - 2.3e-52 178.1 0.0 4.2e-52 177.2 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Glyco_transf_25 PF01755.17 OAG22141.1 - 2.9e-09 37.1 0.0 2.8e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Arrestin_C PF02752.22 OAG22142.1 - 2.1e-13 50.9 0.0 8.7e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 OAG22143.1 - 2.9e-49 167.4 0.0 3.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.13 OAG22144.1 - 2.9e-114 378.2 1.7 1.6e-57 193.9 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Vps51 PF08700.11 OAG22144.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 V-SNARE PF05008.15 OAG22144.1 - 0.093 13.1 1.0 4.3 7.8 0.4 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Cytochrome_C7 PF14522.6 OAG22144.1 - 0.19 11.8 5.0 0.077 13.0 0.6 2.5 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 OAG22144.1 - 1.6 8.8 5.7 3.5 7.7 0.9 2.5 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 OAG22144.1 - 4.7 7.3 11.4 45 4.2 0.0 3.8 3 1 0 3 3 3 0 Double zinc ribbon Rpr2 PF04032.16 OAG22145.1 - 2e-14 53.6 0.3 2e-14 53.6 0.3 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.22 OAG22145.1 - 0.16 11.9 2.5 4.9 7.1 0.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DBR1 PF05011.13 OAG22146.1 - 7.4e-47 159.3 0.2 1.3e-46 158.5 0.2 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAG22146.1 - 8.1e-06 26.5 0.8 2e-05 25.2 1.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase API5 PF05918.11 OAG22146.1 - 0.037 12.8 0.4 0.059 12.2 0.4 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Amidohydro_2 PF04909.14 OAG22149.1 - 4.3e-20 72.7 0.0 5.5e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TMA7 PF09072.10 OAG22150.1 - 2.7e-14 53.8 13.0 2.9e-14 53.6 13.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Sugar_tr PF00083.24 OAG22151.1 - 1.7e-95 320.6 29.7 1.9e-95 320.4 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22151.1 - 6.8e-31 107.5 31.2 3.5e-22 78.8 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG22151.1 - 0.00047 18.6 1.5 0.00047 18.6 1.5 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family L_biotic_typeA PF04604.13 OAG22151.1 - 0.09 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Type-A lantibiotic F-box-like PF12937.7 OAG22152.1 - 3.2e-08 33.3 0.0 9.3e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG22152.1 - 1.3e-06 28.1 0.0 4.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 OAG22152.1 - 0.15 12.4 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 PRANC domain Rad10 PF03834.14 OAG22153.1 - 1.3e-48 163.7 0.0 1.8e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAG22153.1 - 0.016 15.8 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Rox3 PF08633.10 OAG22154.1 - 3.2e-53 181.1 0.1 5.7e-53 180.3 0.1 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit UPF0047 PF01894.17 OAG22158.1 - 0.21 11.7 0.7 2 8.6 0.7 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0047 LRR_4 PF12799.7 OAG22158.1 - 0.91 10.0 6.3 32 5.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_L10 PF00466.20 OAG22159.1 - 5.4e-05 23.3 0.8 0.0055 16.8 0.8 2.8 1 1 0 1 1 1 1 Ribosomal protein L10 tRNA-synt_2b PF00587.25 OAG22160.1 - 6.2e-32 111.0 0.0 9.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG22160.1 - 4.9e-10 39.4 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain DUF1772 PF08592.11 OAG22161.1 - 2.2e-20 73.4 4.8 3.1e-20 72.9 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Ribonuclease_3 PF00636.26 OAG22162.1 - 2.2e-09 37.9 0.0 1.1e-08 35.6 0.0 2.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG22162.1 - 7.1e-08 32.7 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like FAD_binding_4 PF01565.23 OAG22163.1 - 7.1e-29 100.3 1.0 1.1e-28 99.7 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG22163.1 - 2.5e-12 46.7 0.0 5.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Q_salvage PF10343.9 OAG22164.1 - 1.6e-128 428.2 0.3 2e-128 427.9 0.3 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4121 PF13497.6 OAG22164.1 - 0.0034 16.6 0.2 0.0054 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4121) ThiF PF00899.21 OAG22165.1 - 6.2e-72 241.9 0.0 9e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OAG22165.1 - 1.5e-15 57.5 1.3 1.5e-15 57.5 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OAG22165.1 - 5.7e-08 33.0 0.2 0.00047 20.2 0.0 2.6 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OAG22165.1 - 0.0021 18.5 0.1 0.0095 16.4 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG22165.1 - 0.0078 16.3 0.2 0.027 14.5 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAG22166.1 - 4.7e-44 150.2 0.0 4.8e-33 114.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22166.1 - 1.1e-37 129.8 0.0 1.6e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22166.1 - 1.1e-06 28.7 0.1 0.033 14.1 0.0 2.6 2 1 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.8 OAG22166.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Med12-LCEWAV PF12145.8 OAG22166.1 - 0.037 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Meleagrin PF08189.11 OAG22166.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family Helicase_RecD PF05127.14 OAG22166.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase Skp1_POZ PF03931.15 OAG22167.1 - 5.4e-10 39.3 0.0 8.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Choline_kinase PF01633.20 OAG22168.1 - 4.9e-50 170.1 0.0 4.9e-49 166.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OAG22168.1 - 1.2e-08 35.2 0.0 6.7e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sterol-sensing PF12349.8 OAG22169.1 - 3.3e-32 111.4 1.5 7.6e-32 110.3 1.5 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAG22169.1 - 2.3e-09 36.0 2.2 3.9e-09 35.2 1.5 1.5 2 0 0 2 2 2 1 Patched family TPR_12 PF13424.6 OAG22170.1 - 8e-10 38.9 0.1 0.0001 22.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22170.1 - 1.1e-09 37.6 0.0 0.0003 20.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22170.1 - 3.7e-08 33.5 9.7 0.02 15.6 0.1 5.0 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22170.1 - 1.7e-07 30.9 0.0 0.0019 18.3 0.0 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22170.1 - 3.5e-07 30.8 1.7 0.056 14.1 1.9 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG22170.1 - 8.4e-07 28.6 0.1 0.0017 18.1 0.0 3.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG22170.1 - 1.7e-05 25.2 6.2 0.22 12.1 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAG22170.1 - 8.4e-05 22.6 4.5 0.23 11.6 0.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG22170.1 - 0.00026 21.4 2.2 1.8 9.4 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG22170.1 - 0.00038 19.9 0.5 0.0058 16.0 0.1 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 OAG22170.1 - 0.0041 17.1 0.0 1.6 9.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG22170.1 - 0.0052 17.0 0.1 8.8 6.6 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OAG22170.1 - 0.0064 16.2 1.6 0.084 12.6 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 OAG22170.1 - 0.01 16.2 0.0 45 4.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG22170.1 - 0.011 15.5 2.6 38 4.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 OAG22170.1 - 0.012 15.0 0.1 0.044 13.2 0.0 1.8 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 OAG22170.1 - 0.038 13.2 6.5 0.56 9.4 0.5 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22170.1 - 0.087 12.5 1.7 0.38 10.5 0.0 3.0 3 0 0 3 3 3 0 TPR repeat RWD PF05773.22 OAG22171.1 - 1.4e-23 83.4 0.6 1.4e-23 83.4 0.6 1.6 2 0 0 2 2 2 1 RWD domain DUF5641 PF18701.1 OAG22171.1 - 0.069 13.3 0.6 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5641) CCDC71L PF15374.6 OAG22171.1 - 0.56 9.4 4.9 0.68 9.1 4.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DFRP_C PF16543.5 OAG22171.1 - 0.95 10.0 20.5 0.19 12.2 15.7 2.4 2 1 1 3 3 3 0 DRG Family Regulatory Proteins, Tma46 Complex1_LYR PF05347.15 OAG22172.1 - 2e-13 50.2 0.1 4.6e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG22172.1 - 0.031 15.0 2.1 0.038 14.7 0.0 2.1 2 1 0 2 2 2 0 Complex1_LYR-like UQ_con PF00179.26 OAG22173.1 - 9.5e-18 64.2 0.0 1e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG22173.1 - 0.0043 17.3 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.7 OAG22174.1 - 2.1e-38 131.7 7.9 2.1e-38 131.7 0.8 4.1 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAG22174.1 - 3.6e-16 58.5 2.2 4.2e-13 48.4 0.5 2.9 3 0 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 OAG22174.1 - 3.7e-05 23.5 2.4 0.43 10.4 0.0 4.8 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) HEAT PF02985.22 OAG22174.1 - 0.019 15.2 0.4 6.6 7.3 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat Ipi1_N PF12333.8 OAG22174.1 - 0.037 14.6 9.7 0.51 10.9 0.1 4.6 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Fungal_trans PF04082.18 OAG22175.1 - 2.1e-16 59.8 0.0 4.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22175.1 - 7.2e-08 32.4 13.0 1.2e-07 31.8 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TolA_bind_tri PF16331.5 OAG22175.1 - 0.028 14.5 0.9 0.057 13.5 0.9 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation NPV_P10 PF05531.12 OAG22175.1 - 0.028 14.9 0.6 0.063 13.7 0.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC106 PF15794.5 OAG22175.1 - 0.63 9.7 2.4 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CK_II_beta PF01214.18 OAG22176.1 - 1.9e-76 255.9 0.0 6.7e-76 254.1 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 OAG22176.1 - 0.49 8.9 0.8 0.85 8.1 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 OAG22176.1 - 0.62 9.8 5.3 7.6 6.3 2.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spt5_N PF11942.8 OAG22176.1 - 0.72 10.9 17.0 0.22 12.5 6.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4637 PF15470.6 OAG22176.1 - 2.1 8.1 8.3 0.29 10.9 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CENP-B_dimeris PF09026.10 OAG22176.1 - 9.3 6.7 17.5 18 5.8 8.9 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ammonium_transp PF00909.21 OAG22177.1 - 1.6e-114 382.7 28.5 1.8e-114 382.5 28.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 OAG22177.1 - 0.073 13.1 0.7 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF441) Tfb4 PF03850.14 OAG22178.1 - 9.3e-106 353.3 0.0 1.1e-105 353.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.13 OAG22178.1 - 1 9.4 5.1 1.7 8.7 5.1 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type NAD_binding_8 PF13450.6 OAG22179.1 - 3.1e-10 40.1 0.0 9.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG22179.1 - 3.4e-10 39.0 0.1 3.5e-09 35.6 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG22179.1 - 6.4e-08 32.2 0.1 0.0005 19.4 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG22179.1 - 5e-07 29.2 0.0 0.00085 18.6 0.0 2.8 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG22179.1 - 0.00014 21.2 0.1 0.0055 16.0 0.0 2.7 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 OAG22179.1 - 0.00064 19.4 0.5 0.028 14.0 0.2 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG22179.1 - 0.0017 17.7 0.2 0.37 10.0 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG22179.1 - 0.024 14.7 0.0 0.11 12.5 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding CoA_binding PF02629.19 OAG22179.1 - 0.12 13.1 0.1 0.46 11.2 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Fungal_trans PF04082.18 OAG22180.1 - 5e-36 124.1 0.3 1.2e-35 122.9 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22180.1 - 0.00024 21.1 15.5 0.00041 20.4 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAG22181.1 - 1.3e-32 113.1 0.5 1.7e-32 112.7 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG22181.1 - 1.2e-21 76.7 0.1 2.5e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG22181.1 - 3.7e-17 63.0 0.2 2.9e-16 60.1 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG22181.1 - 4.5e-07 30.2 0.1 6.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FF PF01846.19 OAG22182.1 - 9.5e-45 150.6 20.1 1.1e-12 47.9 1.7 7.1 7 0 0 7 7 7 5 FF domain WW PF00397.26 OAG22182.1 - 4.8e-12 45.7 8.0 3.3e-08 33.5 0.7 2.8 2 0 0 2 2 2 2 WW domain DUF5338 PF17273.2 OAG22182.1 - 0.019 15.0 0.2 0.15 12.1 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5338) RhoGAP-FF1 PF16512.5 OAG22182.1 - 0.03 15.0 17.4 0.17 12.6 2.4 5.0 2 1 2 4 4 4 0 p190-A and -B Rho GAPs FF domain Trs65 PF12735.7 OAG22183.1 - 1.5e-83 280.9 0.3 2e-83 280.4 0.3 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 A2M PF00207.22 OAG22183.1 - 0.075 12.9 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Mpv17_PMP22 PF04117.12 OAG22184.1 - 5.1e-20 71.5 0.2 1.2e-19 70.3 0.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.19 OAG22185.1 - 1.2e-152 508.3 1.0 1.3e-152 508.1 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 OAG22185.1 - 0.0029 17.6 0.9 0.15 12.1 0.0 2.8 3 0 0 3 3 3 1 PA domain DUF3530 PF12048.8 OAG22185.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 OAG22186.1 - 5.3e-24 84.0 16.1 6.9e-24 83.7 16.1 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 OAG22187.1 - 7.7e-141 470.1 0.1 9.1e-141 469.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF612 PF04747.12 OAG22187.1 - 0.19 10.8 2.3 0.33 10.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Ank_5 PF13857.6 OAG22188.1 - 1.6e-08 34.7 0.1 3.5e-06 27.2 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG22188.1 - 1.2e-05 25.3 0.0 0.0029 18.0 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OAG22188.1 - 2.2e-05 24.7 0.0 0.038 14.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG22188.1 - 2.4e-05 24.8 0.1 4.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG22188.1 - 3.3e-05 24.4 0.0 0.00012 22.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) sCache_like PF16736.5 OAG22188.1 - 0.099 12.7 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 Single Cache-like PAP2 PF01569.21 OAG22189.1 - 5.9e-26 90.9 1.6 5.9e-26 90.9 1.6 2.4 2 2 0 2 2 2 1 PAP2 superfamily Sulf_transp PF04143.14 OAG22189.1 - 7.3 6.1 9.7 0.086 12.4 1.0 2.0 3 0 0 3 3 3 0 Sulphur transport PEMT PF04191.13 OAG22190.1 - 2.9e-31 108.0 0.8 6.1e-31 107.0 0.8 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Aa_trans PF01490.18 OAG22191.1 - 2.2e-27 95.8 38.3 2.6e-27 95.6 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_cap_E PF03864.15 OAG22191.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein E Pkinase PF00069.25 OAG22192.1 - 1.1e-18 67.6 0.0 3.3e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22192.1 - 5.5e-10 39.0 0.0 6.3e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 OAG22192.1 - 0.004 16.8 0.5 0.0092 15.7 0.1 1.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 OAG22193.1 - 3.6e-34 118.6 0.0 4.5e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HMG_box PF00505.19 OAG22194.1 - 4.5e-05 23.8 1.7 0.00053 20.3 0.5 2.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG22194.1 - 0.00012 22.6 0.4 0.00012 22.6 0.4 2.8 3 0 0 3 3 3 1 HMG-box domain Lipoprotein_9 PF03180.14 OAG22194.1 - 0.0062 15.7 1.0 0.0062 15.7 1.0 1.9 1 1 0 1 1 1 1 NLPA lipoprotein DUF5613 PF18467.1 OAG22194.1 - 0.013 15.9 0.5 0.34 11.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) RGS PF00615.19 OAG22194.1 - 0.052 13.8 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain RNA_pol_Rpc4 PF05132.14 OAG22194.1 - 2.7 8.4 11.3 0.41 11.1 7.1 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Voltage_CLC PF00654.20 OAG22195.1 - 5.6e-88 295.6 18.4 5.6e-88 295.6 18.4 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG22195.1 - 0.00057 20.3 0.1 0.0029 18.0 0.0 2.2 2 0 0 2 2 2 1 CBS domain Tubulin PF00091.25 OAG22196.1 - 5.4e-69 232.3 0.0 3.3e-68 229.8 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG22196.1 - 1.4e-42 144.8 0.1 2.4e-42 144.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAG22196.1 - 5.4e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OAG22196.1 - 0.00062 19.1 0.0 0.0087 15.3 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 OAG22196.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ceramidase PF05875.12 OAG22197.1 - 4.6e-108 360.6 9.3 5.5e-108 360.4 9.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF4199 PF13858.6 OAG22197.1 - 0.025 15.0 11.4 1.8 8.9 1.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF4199) DUF2070 PF09843.9 OAG22197.1 - 0.34 9.1 3.6 0.47 8.7 3.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2568 PF10823.8 OAG22197.1 - 0.37 11.1 5.6 4.5 7.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) Prefoldin_2 PF01920.20 OAG22198.1 - 3.4e-17 62.3 6.0 3.4e-17 62.3 6.0 1.5 1 1 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.15 OAG22198.1 - 0.0047 17.1 6.3 0.12 12.5 0.8 2.2 2 1 0 2 2 2 2 RasGAP C-terminus DUF3552 PF12072.8 OAG22198.1 - 0.0086 15.5 0.7 0.0086 15.5 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Nmad5 PF18757.1 OAG22198.1 - 0.037 14.2 1.5 0.043 14.0 1.5 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 DUF4200 PF13863.6 OAG22198.1 - 0.069 13.6 8.8 1.4 9.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SHE3 PF17078.5 OAG22198.1 - 0.1 12.3 7.6 0.16 11.6 7.6 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 GARS_C PF02843.16 OAG22198.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain bZIP_1 PF00170.21 OAG22198.1 - 1.4 9.0 8.7 0.34 11.0 4.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 OAG22198.1 - 1.8 8.4 11.2 0.22 11.3 2.1 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 OAG22198.1 - 7.8 6.6 14.1 0.33 11.0 6.0 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding 2-oxoacid_dh PF00198.23 OAG22199.1 - 2.5e-72 243.1 0.0 5e-72 242.1 0.0 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG22199.1 - 1.8e-19 69.3 0.1 2.2e-17 62.7 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 OAG22199.1 - 6.3e-12 45.6 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain MRJP PF03022.16 OAG22200.1 - 4.2e-24 85.4 0.1 6.5e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 OAG22200.1 - 0.019 15.0 0.2 19 5.5 0.1 4.2 4 0 0 4 4 4 0 NHL repeat SBBP PF06739.11 OAG22200.1 - 0.052 13.6 0.1 8 6.6 0.0 3.1 3 0 0 3 3 3 0 Beta-propeller repeat Reg_prop PF07494.11 OAG22200.1 - 0.055 13.7 1.1 2.6 8.6 0.1 4.1 4 0 0 4 4 4 0 Two component regulator propeller SLD3 PF08639.10 OAG22201.1 - 1.6e-140 469.4 4.5 2.3e-140 468.9 4.5 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 GET2 PF08690.10 OAG22202.1 - 1.5 8.4 5.5 5.6 6.5 5.5 1.9 1 0 0 1 1 1 0 GET complex subunit GET2 CK_II_beta PF01214.18 OAG22204.1 - 3.6e-76 255.1 0.2 4.8e-76 254.6 0.2 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Zn_clus PF00172.18 OAG22205.1 - 2.6e-09 37.1 10.4 2.6e-09 37.1 10.4 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain fn3_6 PF17766.1 OAG22205.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type-III domain bZIP_1 PF00170.21 OAG22206.1 - 4.1e-07 30.0 1.1 4.1e-07 30.0 1.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG22206.1 - 4e-06 26.8 2.2 8.1e-06 25.8 2.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG22206.1 - 0.0068 16.9 1.2 0.012 16.1 1.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 OAG22206.1 - 0.034 13.9 0.5 0.057 13.2 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Rbsn PF11464.8 OAG22206.1 - 0.035 13.8 0.2 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain GMC_oxred_N PF00732.19 OAG22209.1 - 1.4e-64 218.3 0.0 2.2e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG22209.1 - 2.7e-35 122.0 0.0 5.1e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG22209.1 - 6.5e-09 35.4 1.3 0.00075 18.7 0.2 2.6 2 1 1 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG22209.1 - 3.2e-06 26.6 0.5 0.003 16.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22209.1 - 9.8e-05 22.5 0.3 0.00021 21.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG22209.1 - 0.0003 20.2 2.5 0.016 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG22209.1 - 0.0012 18.5 0.1 0.0056 16.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG22209.1 - 0.0015 17.3 0.5 0.082 11.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG22209.1 - 0.0036 16.4 0.7 0.0099 15.0 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG22209.1 - 0.014 16.0 1.6 0.85 10.2 0.2 3.4 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG22209.1 - 0.026 13.8 0.3 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAG22209.1 - 0.028 13.5 1.2 4 6.4 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HTH_IclR PF09339.10 OAG22211.1 - 0.00098 18.9 0.2 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain Merozoite_SPAM PF07133.11 OAG22212.1 - 0.00086 19.4 0.4 0.0018 18.3 0.4 1.5 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Misat_Tub_SegII PF10644.9 OAG22212.1 - 0.091 13.1 0.2 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain SIR2 PF02146.17 OAG22213.1 - 2.3e-55 187.3 0.0 3.2e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OAG22213.1 - 0.0039 16.9 0.2 0.49 10.1 0.1 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 OAG22213.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) F-box-like PF12937.7 OAG22214.1 - 0.062 13.2 0.6 0.68 9.9 0.2 2.4 2 0 0 2 2 2 0 F-box-like Ribonuc_P_40 PF08584.11 OAG22215.1 - 5.9e-71 239.1 0.0 8.4e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Cu-oxidase_3 PF07732.15 OAG22217.1 - 4.1e-45 152.6 9.2 2.2e-42 143.8 1.2 4.1 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG22217.1 - 3.4e-40 137.0 9.6 1.1e-39 135.3 0.5 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG22217.1 - 1.6e-36 125.8 0.3 5.5e-36 124.1 0.3 1.9 1 0 0 1 1 1 1 Multicopper oxidase Arginase PF00491.21 OAG22218.1 - 1.7e-94 316.5 0.0 2e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG22218.1 - 0.0093 16.2 0.7 0.017 15.4 0.1 1.7 2 0 0 2 2 2 1 UPF0489 domain Fapy_DNA_glyco PF01149.24 OAG22219.1 - 1.5e-32 112.6 0.0 3.8e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 OAG22219.1 - 2.7e-22 78.6 0.0 6.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain NARP1 PF12569.8 OAG22220.1 - 2.6e-210 699.7 29.2 1.3e-208 694.1 25.6 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OAG22220.1 - 1.9e-20 73.1 21.5 0.00013 22.4 0.1 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22220.1 - 6.9e-16 57.0 28.0 0.013 15.6 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22220.1 - 7.7e-15 54.3 15.6 1.8 9.6 0.0 10.7 8 2 3 11 11 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG22220.1 - 6.5e-13 47.9 21.5 0.0059 16.4 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG22220.1 - 1.1e-12 48.0 22.4 0.0027 17.9 0.9 6.3 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAG22220.1 - 6.3e-12 45.5 5.8 0.0005 20.2 0.0 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22220.1 - 7.8e-11 42.4 25.3 0.1 13.3 0.0 9.3 8 1 1 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG22220.1 - 1e-08 34.9 10.7 0.052 14.0 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22220.1 - 2.1e-08 33.7 19.0 1 9.8 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22220.1 - 1.6e-07 31.5 19.3 0.4 11.0 0.2 7.9 6 1 1 7 7 7 2 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 OAG22220.1 - 3.5e-05 22.8 0.1 9.1e-05 21.4 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.6 OAG22220.1 - 4.7e-05 23.0 13.8 0.047 13.4 0.0 5.9 8 0 0 8 8 6 2 TPR repeat TPR_MalT PF17874.1 OAG22220.1 - 0.00013 21.5 4.4 0.3 10.4 2.4 3.5 2 1 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 OAG22220.1 - 0.00021 21.0 9.9 0.37 10.7 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat DUF3287 PF11690.8 OAG22220.1 - 0.012 15.3 1.7 0.018 14.7 0.1 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF3287) TPR_7 PF13176.6 OAG22220.1 - 0.014 15.4 16.7 2.9 8.1 0.0 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAG22220.1 - 0.017 15.5 10.5 0.51 10.8 0.2 4.0 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 OAG22220.1 - 0.025 14.6 17.4 0.56 10.3 0.3 6.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Zn_clus PF00172.18 OAG22220.1 - 0.027 14.6 4.6 0.058 13.5 4.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_4 PF07721.14 OAG22220.1 - 0.032 14.8 1.8 1.2 10.0 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat IHABP4_N PF16174.5 OAG22220.1 - 0.11 13.1 11.6 0.28 11.8 11.6 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PPTA PF01239.22 OAG22220.1 - 0.31 10.8 1.2 22 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat AAA PF00004.29 OAG22221.1 - 1.3e-15 58.0 0.0 2.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OAG22221.1 - 5e-12 45.8 0.4 1.9e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 OAG22221.1 - 1.2e-11 45.3 0.0 8.6e-11 42.5 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.18 OAG22221.1 - 8.1e-10 38.6 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 OAG22221.1 - 1.9e-09 37.9 0.0 8.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG22221.1 - 0.0014 19.0 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG22221.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 OAG22221.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG22221.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG22221.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 OAG22221.1 - 0.057 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG22221.1 - 0.09 13.3 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 OAG22221.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Single-stranded DNA-binding protein PIF1 PF05970.14 OAG22221.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 OAG22221.1 - 0.14 12.5 0.0 0.53 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 OAG22221.1 - 0.15 12.1 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE bZIP_1 PF00170.21 OAG22222.1 - 0.0003 20.8 8.3 0.00048 20.2 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG22222.1 - 0.0043 17.1 7.8 0.0062 16.6 7.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG22222.1 - 0.23 12.0 7.7 0.06 13.9 4.8 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Rrn6 PF10214.9 OAG22222.1 - 1.7 7.0 12.3 2.2 6.7 12.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 OAG22224.1 - 1.3e-26 94.1 0.2 1.9e-16 60.9 0.0 2.7 2 1 1 3 3 3 2 DDHD domain Serglycin PF04360.12 OAG22224.1 - 4.8 7.1 6.4 11 6.0 6.4 1.5 1 0 0 1 1 1 0 Serglycin TMEM208_SND2 PF05620.11 OAG22227.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.2 2 2 2 4 4 4 0 SRP-independent targeting protein 2/TMEM208 ABC_export PF16962.5 OAG22227.1 - 4 5.8 20.0 2 6.7 15.9 2.2 2 0 0 2 2 2 0 Putative ABC exporter EHN PF06441.12 OAG22228.1 - 3.1e-35 120.8 1.9 1.1e-33 115.9 0.1 2.3 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG22228.1 - 3.1e-09 36.9 0.0 6.9e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG22228.1 - 0.0048 17.5 3.2 0.021 15.4 3.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_3 PF00202.21 OAG22229.1 - 3.3e-48 164.3 0.1 4e-30 104.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III DUF5108 PF17133.4 OAG22229.1 - 0.064 13.2 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5108) Aminotran_5 PF00266.19 OAG22229.1 - 0.1 11.5 0.1 0.64 8.9 0.1 2.0 1 1 0 1 1 1 0 Aminotransferase class-V DHO_dh PF01180.21 OAG22231.1 - 9.1e-19 67.8 0.0 1.8e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OAG22231.1 - 0.46 9.8 2.7 0.93 8.8 2.7 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase IPK PF03770.16 OAG22232.1 - 1.6e-57 194.6 0.0 3.8e-57 193.4 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_8 PF13855.6 OAG22233.1 - 8e-17 60.8 34.7 3.2e-05 23.6 6.0 6.1 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OAG22233.1 - 5.9e-14 52.0 46.8 0.0024 18.3 4.1 7.8 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAG22233.1 - 2.8e-12 46.5 16.0 9.2e-05 22.0 0.3 4.6 2 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 OAG22233.1 - 0.024 14.7 22.6 0.78 9.9 0.1 7.5 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 OAG22233.1 - 1.1 10.0 29.8 3.4 8.6 0.2 8.4 8 0 0 8 8 8 0 Leucine Rich Repeat UNC45-central PF11701.8 OAG22234.1 - 4.3e-45 153.4 6.6 1.5e-44 151.7 3.8 2.9 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 OAG22234.1 - 0.0077 16.6 8.8 0.052 13.9 0.1 5.1 4 1 1 5 5 5 1 HEAT repeats TetR_C_28 PF17937.1 OAG22234.1 - 0.11 13.0 2.4 0.62 10.6 0.0 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NPA PF16469.5 OAG22234.1 - 0.25 11.9 5.1 11 6.6 0.6 2.6 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 ABM PF03992.16 OAG22235.1 - 0.0018 18.3 0.0 0.08 13.1 0.0 2.5 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase Phage_connect_1 PF05135.13 OAG22235.1 - 0.015 15.8 0.1 0.061 13.8 0.1 2.1 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein p450 PF00067.22 OAG22236.1 - 7.6e-47 160.1 0.0 1.1e-46 159.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ORC6 PF05460.13 OAG22238.1 - 6.1e-45 154.0 6.1 4.1e-44 151.3 6.1 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Brix PF04427.18 OAG22243.1 - 4.2e-31 108.6 0.0 5.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain PRMT5_TIM PF17285.2 OAG22244.1 - 2.2e-73 246.6 0.0 3e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OAG22244.1 - 1e-70 237.1 0.0 1.6e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OAG22244.1 - 1.3e-57 194.6 0.0 2.7e-57 193.5 0.0 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 OAG22244.1 - 0.055 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Matrilin_ccoil PF10393.9 OAG22244.1 - 0.14 12.0 0.1 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin OB_NTP_bind PF07717.16 OAG22245.1 - 1.1e-23 83.3 0.0 4e-23 81.6 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG22245.1 - 1.8e-17 63.6 0.0 4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG22245.1 - 2.9e-10 40.5 0.0 9e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG22245.1 - 7.5e-07 29.1 0.1 1.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG22245.1 - 1.3e-06 28.7 0.0 5.2e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAG22245.1 - 0.00046 19.9 0.1 0.0014 18.3 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 OAG22245.1 - 0.0076 16.2 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 OAG22245.1 - 0.0081 16.5 0.1 0.024 15.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAG22245.1 - 0.013 16.0 0.1 0.043 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG22245.1 - 0.014 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG22245.1 - 0.023 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAG22245.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RPA43_OB PF17875.1 OAG22246.1 - 1.3e-18 67.8 0.4 1.3e-18 67.8 0.4 2.9 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAG22246.1 - 1.8e-07 31.4 0.0 3.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF423 PF04241.15 OAG22247.1 - 1.2e-24 86.3 1.8 2.1e-24 85.5 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.20 OAG22247.1 - 0.017 15.0 5.6 0.021 14.6 5.6 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 p450 PF00067.22 OAG22248.1 - 9.3e-57 192.8 0.0 1.2e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DctQ PF04290.12 OAG22249.1 - 4.6 7.2 13.8 0.58 10.1 8.5 2.2 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Asp PF00026.23 OAG22250.1 - 5.7e-63 213.2 4.1 7.2e-63 212.9 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG22250.1 - 1.4e-14 54.8 1.7 9.5e-08 32.5 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal p450 PF00067.22 OAG22251.1 - 1.6e-53 182.2 0.0 2.1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG22252.1 - 1.7e-36 125.9 23.9 1.7e-36 125.9 23.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Hydrolase PF00702.26 OAG22253.1 - 2.8e-07 31.0 0.0 3.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG22253.1 - 6.4e-06 26.4 0.0 9.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3492 PF11997.8 OAG22253.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DAO PF01266.24 OAG22254.1 - 1.3e-44 153.2 0.2 1.6e-44 153.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG22254.1 - 8e-06 25.3 0.4 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG22254.1 - 0.00062 19.8 0.2 0.0085 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG22254.1 - 0.00093 19.4 0.1 0.0032 17.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG22254.1 - 0.0034 16.1 0.1 0.099 11.3 0.0 2.1 1 1 1 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG22254.1 - 0.018 14.3 0.1 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG22254.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 OAG22254.1 - 0.028 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 OAG22254.1 - 0.13 11.3 2.8 0.97 8.4 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 OAG22254.1 - 0.21 10.7 0.4 0.6 9.1 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldedh PF00171.22 OAG22256.1 - 1.1e-183 611.0 1.4 1.3e-183 610.8 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG22256.1 - 0.0014 18.1 0.1 0.63 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RRM_1 PF00076.22 OAG22257.1 - 1.5e-10 40.7 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAG22257.1 - 2.3e-06 28.1 6.8 2.3e-06 28.1 6.8 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 OAG22257.1 - 1.9e-05 24.4 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FXMRP1_C_core PF12235.8 OAG22257.1 - 1.2 9.7 6.1 1.4 9.5 0.6 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Clathrin PF00637.20 OAG22258.1 - 8.3e-22 77.6 3.0 1.2e-19 70.6 2.6 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 OAG22258.1 - 4.2e-20 71.7 0.1 1.4e-19 70.1 0.1 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 OAG22258.1 - 2.4e-07 30.5 8.4 4.7e-07 29.6 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG22258.1 - 1.7e-05 24.6 6.4 3.1e-05 23.8 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 OAG22258.1 - 2e-05 24.5 9.4 4.1e-05 23.5 9.4 1.5 1 0 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.6 OAG22258.1 - 0.0017 18.7 7.9 0.0031 17.8 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG22258.1 - 0.0031 17.5 7.1 0.0093 16.0 7.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger TPR_11 PF13414.6 OAG22258.1 - 0.011 15.3 1.1 0.027 14.1 0.3 2.1 2 0 0 2 2 1 0 TPR repeat zf-ANAPC11 PF12861.7 OAG22258.1 - 0.024 14.7 1.6 0.055 13.5 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG22258.1 - 0.055 13.4 7.8 0.1 12.5 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps8 PF12816.7 OAG22258.1 - 0.11 12.0 1.5 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.7 OAG22258.1 - 0.11 12.7 5.1 0.25 11.6 5.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAG22258.1 - 0.14 12.3 7.7 0.29 11.3 7.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_14 PF13428.6 OAG22258.1 - 0.19 12.6 2.9 14 6.9 0.1 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat Vps39_2 PF10367.9 OAG22258.1 - 0.2 12.1 3.3 0.12 12.8 0.7 2.0 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 OAG22258.1 - 0.21 12.5 0.3 29 5.7 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 OAG22258.1 - 0.5 10.3 5.6 0.87 9.5 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OAG22258.1 - 1.3 8.9 4.8 3.1 7.7 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KIP1 PF07765.12 OAG22258.1 - 2 8.6 4.3 0.6 10.3 0.6 2.1 2 0 0 2 2 1 0 KIP1-like protein zf-RING_11 PF17123.5 OAG22258.1 - 2.2 8.1 9.3 3.7 7.4 5.8 2.5 2 0 0 2 2 2 0 RING-like zinc finger ANAPC3 PF12895.7 OAG22258.1 - 2.5 8.4 6.2 15 5.9 0.2 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PHD PF00628.29 OAG22258.1 - 2.9 7.8 7.4 5.9 6.9 7.4 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OAG22258.1 - 6.9 6.7 7.3 1.5 8.8 2.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Fungal_trans PF04082.18 OAG22259.1 - 4.6e-13 48.8 0.0 7.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22259.1 - 0.00013 22.1 7.7 0.0002 21.4 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG22260.1 - 8.1e-89 298.5 14.4 9.4e-89 298.3 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22260.1 - 2.3e-32 112.3 48.6 4e-27 95.1 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 OAG22260.1 - 0.014 15.6 5.8 0.014 15.6 5.8 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3792) AnmK PF03702.14 OAG22261.1 - 6.3e-83 278.9 0.0 7.1e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Methyltransf_2 PF00891.18 OAG22261.1 - 0.0031 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Tyrosinase PF00264.20 OAG22262.1 - 1.2e-46 159.8 4.3 1.6e-46 159.4 4.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NAD_binding_10 PF13460.6 OAG22263.1 - 3.7e-11 43.2 0.2 5.6e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG22263.1 - 3.3e-08 33.4 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG22263.1 - 2.2e-05 24.0 0.1 3.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG22263.1 - 8.3e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG22263.1 - 0.0049 17.0 0.2 0.0085 16.2 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAG22263.1 - 0.013 15.9 0.2 0.027 14.9 0.2 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Barstar PF01337.18 OAG22263.1 - 0.014 15.4 0.5 0.052 13.6 0.0 2.2 2 1 1 3 3 3 0 Barstar (barnase inhibitor) F420_oxidored PF03807.17 OAG22263.1 - 0.023 15.3 0.3 0.051 14.1 0.3 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 OAG22263.1 - 0.026 14.4 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 OAG22263.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 OAG22263.1 - 0.046 13.8 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 OAG22263.1 - 0.058 12.4 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 OAG22263.1 - 0.11 13.3 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 OAG22263.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 OAG22263.1 - 0.18 11.2 1.9 6.9 6.1 0.1 2.3 1 1 1 2 2 2 0 short chain dehydrogenase DFP PF04127.15 OAG22263.1 - 0.19 11.6 0.3 0.35 10.7 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HeLo PF14479.6 OAG22264.1 - 8.4e-07 29.0 1.8 1.9e-06 27.9 1.6 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation PMC2NT PF08066.12 OAG22264.1 - 0.057 14.1 2.8 0.53 11.0 0.9 3.0 2 1 0 2 2 2 0 PMC2NT (NUC016) domain AAA PF00004.29 OAG22265.1 - 2.9e-16 60.1 0.0 7.6e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG22265.1 - 0.0055 17.1 0.1 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAG22265.1 - 0.0073 16.7 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG22265.1 - 0.13 12.5 2.7 0.99 9.7 0.2 2.7 2 1 1 3 3 3 0 AAA domain CFEM PF05730.11 OAG22266.1 - 2.1e-15 56.6 10.0 5.8e-15 55.1 10.0 1.8 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 OAG22267.1 - 3.6e-40 135.2 15.6 1.7e-07 31.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG22267.1 - 1.5e-06 28.4 2.5 0.91 9.9 0.1 5.4 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG22267.1 - 0.042 12.5 1.3 12 4.4 0.0 3.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Peptidase_M32 PF02074.15 OAG22267.1 - 0.075 11.8 0.6 0.11 11.2 0.6 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase ABC_tran_Xtn PF12848.7 OAG22267.1 - 0.42 10.7 4.4 0.93 9.6 4.4 1.6 1 0 0 1 1 1 0 ABC transporter PXA PF02194.15 OAG22268.1 - 4e-49 167.1 0.3 7.2e-47 159.7 0.1 3.1 3 1 0 3 3 3 1 PXA domain Nexin_C PF08628.12 OAG22268.1 - 1.8e-25 89.6 0.1 5.4e-25 88.1 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 OAG22268.1 - 2.1e-21 76.0 0.4 4.4e-21 75.0 0.4 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 OAG22268.1 - 1.5e-11 44.6 0.2 4.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain RRP36 PF06102.12 OAG22268.1 - 0.094 12.7 6.1 0.06 13.3 1.9 2.4 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 AAA_12 PF13087.6 OAG22269.1 - 3.4e-39 134.5 0.0 6.8e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG22269.1 - 4.1e-23 82.5 0.2 4.1e-23 82.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG22269.1 - 2e-09 37.9 1.2 1.7e-08 34.9 0.1 3.1 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 OAG22269.1 - 2.5e-07 30.3 0.2 0.0014 18.0 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAG22269.1 - 1.1e-05 25.2 0.2 0.0084 15.8 0.0 2.9 2 1 1 3 3 3 2 AAA domain ResIII PF04851.15 OAG22269.1 - 0.0036 17.3 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cep57_CLD PF14073.6 OAG22269.1 - 0.024 14.6 0.2 0.11 12.5 0.2 2.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CREPT PF16566.5 OAG22269.1 - 0.034 14.3 0.8 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Gp58 PF07902.11 OAG22269.1 - 0.056 11.7 1.7 0.095 11.0 1.7 1.2 1 0 0 1 1 1 0 gp58-like protein HAUS2 PF15003.6 OAG22269.1 - 0.096 12.4 4.6 0.035 13.8 0.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF979 PF06166.12 OAG22271.1 - 0.019 14.1 0.2 0.031 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF4010 PF13194.6 OAG22271.1 - 0.049 13.3 2.6 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) DUF2070 PF09843.9 OAG22271.1 - 2.9 6.1 7.3 0.14 10.4 0.6 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) NAD_binding_8 PF13450.6 OAG22272.1 - 4.3e-10 39.7 0.1 1.3e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG22272.1 - 2.9e-08 33.4 0.0 3e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 OAG22272.1 - 3.6e-07 29.8 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG22272.1 - 1.9e-05 24.0 0.1 2.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG22272.1 - 2.9e-05 23.5 0.0 7e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG22272.1 - 6.1e-05 21.9 0.8 9e-05 21.3 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAG22272.1 - 0.00022 20.5 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG22272.1 - 0.00037 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG22272.1 - 0.00067 18.8 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG22272.1 - 0.002 17.5 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG22272.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG22272.1 - 0.017 15.1 0.1 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG22272.1 - 0.027 13.5 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG22272.1 - 0.18 12.4 0.0 0.67 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG22272.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.19 OAG22275.1 - 5.6e-59 199.9 0.0 7.7e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG22275.1 - 4.5e-27 95.3 0.0 1.6e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAG22275.1 - 8.5e-08 31.8 0.6 0.0045 16.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG22275.1 - 8.8e-07 28.3 0.2 0.007 15.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG22275.1 - 3.4e-05 23.6 0.1 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG22275.1 - 5.5e-05 22.6 0.1 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22275.1 - 0.00016 21.8 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG22275.1 - 0.0024 17.0 0.1 0.039 13.0 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG22275.1 - 0.0029 16.4 0.0 0.076 11.7 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG22275.1 - 0.0075 16.8 0.4 0.28 11.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG22275.1 - 0.01 15.1 1.9 0.027 13.7 0.1 2.4 3 0 0 3 3 3 0 Thi4 family TrkA_N PF02254.18 OAG22275.1 - 0.019 15.2 0.1 0.049 13.9 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAG22275.1 - 0.061 13.3 0.8 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lipase_GDSL_2 PF13472.6 OAG22278.1 - 4.3e-17 63.1 1.4 5.1e-17 62.8 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG22278.1 - 5.8e-07 29.7 0.2 7.7e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pterin_bind PF00809.22 OAG22278.1 - 0.014 15.1 0.5 0.035 13.8 0.4 1.7 1 1 0 1 1 1 0 Pterin binding enzyme DeoC PF01791.9 OAG22278.1 - 0.21 11.2 2.8 1.1 8.8 1.2 2.5 1 1 2 3 3 3 0 DeoC/LacD family aldolase DUF3573 PF12097.8 OAG22278.1 - 0.68 8.7 5.9 0.39 9.5 2.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) Rhomboid PF01694.22 OAG22279.1 - 1.5e-17 63.9 9.5 1.5e-17 63.9 9.5 1.6 2 0 0 2 2 2 1 Rhomboid family ZnuA PF01297.17 OAG22279.1 - 0.34 10.3 1.5 0.55 9.6 1.5 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic CPBP PF02517.16 OAG22279.1 - 3.4 8.1 6.3 68 3.9 6.3 2.5 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease PI-PLC-X PF00388.19 OAG22280.1 - 6.2e-11 42.1 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Spore-coat_CotD PF11122.8 OAG22280.1 - 0.16 12.8 0.1 0.16 12.8 0.1 2.6 3 0 0 3 3 3 0 Inner spore coat protein D SIR2 PF02146.17 OAG22281.1 - 4.7e-26 91.8 0.0 1.4e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 Sir2 family IL7 PF01415.16 OAG22281.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Interleukin 7/9 family Med16 PF11635.8 OAG22282.1 - 2.2e-162 541.8 0.0 2.5e-162 541.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Fer4_10 PF13237.6 OAG22282.1 - 0.064 13.4 0.3 0.41 10.8 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain ANAPC4_WD40 PF12894.7 OAG22282.1 - 0.11 12.7 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain YchF-GTPase_C PF06071.13 OAG22283.1 - 2e-33 114.4 0.1 6e-33 112.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAG22283.1 - 3e-16 59.5 0.0 7.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG22283.1 - 0.00062 19.3 0.0 0.002 17.7 0.0 1.9 2 1 1 3 3 3 1 Ferrous iron transport protein B TGS PF02824.21 OAG22283.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 OAG22283.1 - 0.034 14.2 0.1 1.1 9.3 0.0 2.8 2 1 1 3 3 3 0 Dynamin family AAA_15 PF13175.6 OAG22283.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OAG22283.1 - 1.8 9.0 6.1 27 5.2 6.1 2.5 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.14 OAG22284.1 - 8.5e-34 116.6 0.0 1.1e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 OAG22284.1 - 0.00033 20.9 0.2 0.00065 20.0 0.0 1.5 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF778 PF05608.12 OAG22284.1 - 0.021 15.2 0.1 0.04 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) RhlB PF12300.8 OAG22284.1 - 0.048 13.8 0.6 0.076 13.2 0.6 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Ribosomal_S11 PF00411.19 OAG22285.1 - 6.7e-08 32.9 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 OAG22286.1 - 1.6e-35 122.4 0.0 2.8e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain NOA36 PF06524.12 OAG22286.1 - 6.3 6.0 8.4 9.9 5.4 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAG22286.1 - 7 4.8 10.3 10 4.3 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein 4HBT PF03061.22 OAG22287.1 - 3.3e-10 40.2 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Kelch_5 PF13854.6 OAG22288.1 - 3.6e-05 23.6 2.5 0.0092 15.9 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OAG22288.1 - 0.87 10.0 10.4 0.48 10.8 0.9 4.8 6 1 0 6 6 6 0 Galactose oxidase, central domain Ribosomal_L26 PF16906.5 OAG22289.1 - 2.2e-39 133.8 2.4 2.9e-39 133.4 2.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAG22289.1 - 2.4e-05 24.1 0.4 4.9e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 KOW motif OrsD PF12013.8 OAG22290.1 - 0.0043 17.5 0.4 0.024 15.1 0.4 2.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 OAG22290.1 - 0.027 15.1 1.0 0.027 15.1 1.0 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 OAG22290.1 - 0.048 13.8 3.1 0.075 13.2 3.1 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DFRP_C PF16543.5 OAG22291.1 - 1.7e-27 95.7 7.5 1.7e-27 95.7 7.5 3.7 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 OAG22291.1 - 2.4e-06 27.3 2.1 2.4e-06 27.3 2.1 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG22291.1 - 7.5e-06 25.6 11.8 7.5e-05 22.4 2.6 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 OAG22291.1 - 3e-05 24.7 3.4 3e-05 24.7 3.4 4.0 2 2 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 OAG22291.1 - 0.00012 22.1 8.4 0.00012 22.1 8.4 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 OAG22291.1 - 0.002 18.3 0.5 0.18 12.1 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAG22291.1 - 0.01 16.3 13.7 0.058 13.9 5.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FAD_binding_3 PF01494.19 OAG22293.1 - 3.7e-75 253.3 0.0 4.8e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG22293.1 - 9.9e-36 123.3 0.0 1.7e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG22293.1 - 5.5e-05 22.9 0.1 0.0047 16.6 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG22293.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG22293.1 - 0.006 15.8 0.0 0.016 14.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG22293.1 - 0.014 15.9 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG22293.1 - 0.041 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OAG22293.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 OAG22293.1 - 0.067 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 OAG22293.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 OAG22293.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family UDPGT PF00201.18 OAG22294.1 - 0.00064 18.6 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase G-patch PF01585.23 OAG22295.1 - 5.3e-05 23.0 0.4 0.00011 22.0 0.4 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 OAG22296.1 - 8.6e-15 54.7 0.0 8.6e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22296.1 - 3.2e-06 26.9 0.0 0.00053 19.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22296.1 - 4.9e-06 26.6 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG22296.1 - 0.00035 20.1 0.0 0.00099 18.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG22296.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG22296.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG22296.1 - 0.062 12.7 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TMIE PF16038.5 OAG22296.1 - 1.4 8.9 3.5 2.8 7.9 3.5 1.5 1 0 0 1 1 1 0 TMIE protein F-box-like PF12937.7 OAG22297.1 - 1.5e-07 31.2 1.2 3.7e-07 29.9 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG22297.1 - 0.011 15.7 0.6 0.011 15.7 0.6 2.0 2 0 0 2 2 2 0 F-box domain DUF3824 PF12868.7 OAG22297.1 - 0.16 12.7 0.1 0.29 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) UPF0020 PF01170.18 OAG22298.1 - 5.9e-08 32.6 0.0 0.00065 19.4 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 DUF2417 PF10329.9 OAG22300.1 - 0.087 12.2 1.9 0.14 11.5 1.9 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) TPR_1 PF00515.28 OAG22302.1 - 1e-07 31.4 0.1 0.011 15.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22302.1 - 4.8e-06 26.8 0.5 1.6e-05 25.1 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22302.1 - 8.2e-06 25.5 0.1 0.16 12.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG22302.1 - 6.4e-05 22.7 0.0 0.01 15.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22302.1 - 0.00075 19.1 0.1 0.00075 19.1 0.1 2.5 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OAG22302.1 - 0.14 12.6 3.2 0.2 12.2 0.4 2.6 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22302.1 - 0.37 11.7 1.9 15 6.8 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.6 OAG22303.1 - 7.7e-21 75.0 0.0 1.5e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG22303.1 - 4.7e-13 49.9 0.1 2.1e-11 44.5 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG22303.1 - 0.0013 18.7 0.0 0.0046 17.0 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG22303.1 - 0.0025 17.9 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG22303.1 - 0.035 14.5 0.0 0.14 12.6 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase NT5C PF06941.12 OAG22303.1 - 0.085 12.7 0.0 0.42 10.5 0.0 1.9 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Stimulus_sens_1 PF13756.6 OAG22303.1 - 0.094 13.3 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain CS PF04969.16 OAG22304.1 - 2.2e-07 31.8 0.1 3.5e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 CS domain DUF4202 PF13875.6 OAG22304.1 - 0.064 13.2 0.2 0.089 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Forkhead_N PF08430.12 OAG22304.1 - 0.21 12.2 15.3 0.35 11.5 15.3 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Snf7 PF03357.21 OAG22305.1 - 1.1e-25 90.2 17.2 1.1e-25 90.2 17.2 1.5 1 1 1 2 2 2 1 Snf7 7TMR-HDED PF07697.11 OAG22305.1 - 0.073 13.2 11.6 0.12 12.5 11.6 1.4 1 1 0 1 1 1 0 7TM-HD extracellular GAS PF13851.6 OAG22305.1 - 0.31 10.3 17.1 0.017 14.5 9.3 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding MerR-DNA-bind PF09278.11 OAG22305.1 - 0.71 10.4 11.4 0.3 11.7 0.5 3.4 3 0 0 3 3 3 0 MerR, DNA binding CRR7 PF12095.8 OAG22305.1 - 5 7.6 9.0 0.63 10.5 0.7 3.1 3 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 L31 PF09784.9 OAG22305.1 - 7 7.1 9.4 1.8 9.0 4.8 2.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 YlqD PF11068.8 OAG22305.1 - 8.8 6.7 22.5 1.5 9.2 14.7 2.4 2 1 0 2 2 2 0 YlqD protein Zn_clus PF00172.18 OAG22306.1 - 0.014 15.5 7.9 0.033 14.3 7.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop52 PF05997.12 OAG22308.1 - 4.3e-70 235.9 3.6 5.7e-70 235.5 3.6 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 OAG22308.1 - 0.013 15.7 0.1 0.04 14.0 0.1 1.8 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair SET PF00856.28 OAG22309.1 - 1.3e-21 77.7 0.2 7.7e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAG22309.1 - 2.2e-14 54.0 4.8 2.2e-14 54.0 4.8 2.3 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 OAG22309.1 - 0.086 12.8 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MMU163 PF17119.5 OAG22309.1 - 0.24 10.5 0.9 0.41 9.8 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Pkinase PF00069.25 OAG22310.1 - 1.5e-72 244.2 0.0 2.2e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22310.1 - 6.4e-31 107.6 0.0 2.9e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG22310.1 - 3.4e-06 26.6 0.1 0.52 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 OAG22310.1 - 0.016 14.0 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAG22310.1 - 0.016 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG22310.1 - 0.087 12.7 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpc82 PF05645.13 OAG22310.1 - 3.2 7.5 6.7 0.43 10.3 2.1 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Mre11_DNA_bind PF04152.14 OAG22313.1 - 5.2e-54 183.1 2.1 2e-53 181.2 2.1 2.0 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAG22313.1 - 1.4e-16 61.6 3.2 2.3e-16 60.9 3.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG22313.1 - 1.5e-05 25.2 3.9 0.00011 22.4 3.9 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S19 PF00203.21 OAG22314.1 - 1.4e-26 92.2 0.0 1.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF5126 PF17166.4 OAG22314.1 - 0.025 14.4 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) TFIID_30kDa PF03540.13 OAG22315.1 - 6.1e-23 80.5 0.2 1.2e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit F-box PF00646.33 OAG22316.1 - 0.007 16.2 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG22316.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like Chor_lyase PF04345.13 OAG22316.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Chorismate lyase ATP-synt_ab PF00006.25 OAG22317.1 - 1.2e-109 365.0 0.0 1.6e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OAG22317.1 - 4.2e-46 155.7 0.0 8.4e-46 154.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OAG22317.1 - 3.3e-16 59.6 1.3 6.4e-16 58.6 1.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RRF PF01765.19 OAG22317.1 - 0.12 12.3 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Holin_BhlA PF10960.8 OAG22317.1 - 0.34 10.9 0.1 0.34 10.9 0.1 1.7 2 0 0 2 2 2 0 BhlA holin family Dynamin_M PF01031.20 OAG22318.1 - 8.8e-102 340.1 0.1 2.3e-101 338.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAG22318.1 - 3.6e-57 193.1 0.6 6.7e-57 192.2 0.1 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAG22318.1 - 4.9e-31 106.7 5.6 1.2e-30 105.5 5.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG22318.1 - 1.3e-05 25.3 0.4 6.2e-05 23.1 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OAG22318.1 - 0.06 13.0 0.9 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_L27 PF01016.19 OAG22319.1 - 5.9e-29 99.9 0.1 1.1e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein RRN9 PF10680.9 OAG22319.1 - 0.008 16.4 0.5 0.019 15.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor CoA_transf_3 PF02515.17 OAG22320.1 - 2.1e-65 221.3 0.0 4e-65 220.3 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III NAAA-beta PF15508.6 OAG22321.1 - 4.1e-10 39.8 0.1 8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2590 PF10761.9 OAG22321.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) Fungal_trans_2 PF11951.8 OAG22322.1 - 7.8e-55 186.2 4.3 1.2e-54 185.7 4.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22322.1 - 2e-06 27.8 4.4 3.4e-06 27.1 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob_synth_C PF06463.13 OAG22322.1 - 0.00046 20.1 1.0 0.0042 17.0 0.1 2.8 3 0 0 3 3 3 1 Molybdenum Cofactor Synthesis C HET PF06985.11 OAG22323.1 - 2.2e-16 60.6 1.2 4.3e-16 59.6 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SCP2 PF02036.17 OAG22323.1 - 0.036 14.5 0.0 0.6 10.6 0.0 2.7 3 0 0 3 3 3 0 SCP-2 sterol transfer family Fungal_trans_2 PF11951.8 OAG22324.1 - 0.00013 20.9 0.1 0.00028 19.8 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_2 PF00328.22 OAG22325.1 - 2.1e-38 132.7 0.0 3.1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 OAG22326.1 - 1.7e-67 227.6 0.0 2.5e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22326.1 - 1.9e-46 158.5 0.0 2.8e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG22326.1 - 1.6e-06 27.2 0.2 4.2e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAG22326.1 - 0.00036 19.9 0.0 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG22326.1 - 0.002 18.1 0.1 2.4 8.0 0.0 3.1 3 1 1 4 4 4 2 Phosphotransferase enzyme family DUF4048 PF13257.6 OAG22327.1 - 1e-29 104.2 16.7 1e-29 104.2 16.7 3.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4048) Tim17 PF02466.19 OAG22328.1 - 2.4e-41 140.6 4.7 2.4e-41 140.6 4.7 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SAP130_C PF16014.5 OAG22328.1 - 0.22 10.6 3.5 0.27 10.3 3.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus NOB1_Zn_bind PF08772.11 OAG22329.1 - 6.3e-30 103.2 3.0 1.3e-29 102.1 3.0 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAG22329.1 - 2e-28 98.7 0.1 2e-28 98.7 0.1 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 OAG22329.1 - 0.013 15.1 0.3 0.013 15.1 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 OAG22329.1 - 0.017 15.8 0.3 0.042 14.6 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon family Cript PF10235.9 OAG22329.1 - 0.039 14.5 0.9 0.13 12.8 0.9 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT MqsA_antitoxin PF15731.5 OAG22329.1 - 0.11 12.6 7.5 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DZR PF12773.7 OAG22329.1 - 0.27 11.3 2.0 0.52 10.4 2.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF2321 PF10083.9 OAG22329.1 - 0.77 9.4 5.7 0.12 12.1 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-ribbon_8 PF09723.10 OAG22329.1 - 0.87 9.8 5.6 0.15 12.2 1.7 1.8 2 0 0 2 2 2 0 Zinc ribbon domain RecR PF02132.15 OAG22329.1 - 0.98 9.0 3.7 1.3 8.7 2.6 1.8 1 1 1 2 2 2 0 RecR protein TSP_NTD PF17804.1 OAG22329.1 - 5.5 7.2 8.5 3 8.1 4.9 2.3 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Terpene_synth_C PF03936.16 OAG22330.1 - 0.0021 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain WD40 PF00400.32 OAG22333.1 - 2.4e-25 88.3 14.0 4.4e-05 24.2 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 OAG22333.1 - 9e-05 21.9 1.3 0.15 11.4 0.1 3.3 4 0 0 4 4 4 2 WD40-like domain ANAPC4_WD40 PF12894.7 OAG22333.1 - 0.00027 21.2 0.1 0.79 10.1 0.0 4.5 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OAG22333.1 - 0.00081 19.2 1.1 1.5 8.9 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat Nup160 PF11715.8 OAG22333.1 - 0.051 12.2 0.8 0.4 9.3 0.0 2.7 4 1 0 4 4 4 0 Nucleoporin Nup120/160 Voldacs PF03517.13 OAG22334.1 - 5.3e-18 65.5 0.1 1.3e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling SPW PF03779.14 OAG22335.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 SPW repeat Syndecan PF01034.20 OAG22335.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Laminin_G_3 PF13385.6 OAG22336.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily MtrG PF04210.13 OAG22336.1 - 0.37 10.7 1.7 0.66 9.9 1.7 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SKG6 PF08693.10 OAG22336.1 - 2.2 7.7 8.4 4.3 6.8 8.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pmp3 PF01679.17 OAG22337.1 - 3.9e-21 75.0 8.8 5.5e-21 74.5 8.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3481 PF11980.8 OAG22337.1 - 0.53 10.0 2.1 0.76 9.5 2.1 1.3 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Ribosomal_L19 PF01245.20 OAG22338.1 - 2.8e-13 49.8 0.1 5.9e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 NmrA PF05368.13 OAG22340.1 - 6.4e-69 232.1 0.0 7.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG22340.1 - 3.6e-08 33.5 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Asparaginase PF00710.20 OAG22341.1 - 3.2e-58 196.4 0.0 5.2e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG22341.1 - 1.2e-26 93.1 0.1 2.5e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain NAP PF00956.18 OAG22343.1 - 8.7e-24 84.1 18.2 7e-23 81.2 12.2 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) kleA_kleC PF17383.2 OAG22343.1 - 0.046 14.1 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A SURF2 PF05477.11 OAG22343.1 - 3.1 7.4 6.7 5.9 6.5 6.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Potassium_chann PF11404.8 OAG22343.1 - 3.5 7.5 3.9 6.9 6.6 3.9 1.4 1 0 0 1 1 1 0 Potassium voltage-gated channel Glyco_hydro_1 PF00232.18 OAG22344.1 - 4.5e-101 338.5 0.9 7e-101 337.9 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 WD40 PF00400.32 OAG22344.1 - 1.8e-18 66.6 11.4 0.00027 21.7 0.1 6.9 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG22344.1 - 1.9e-13 50.5 0.1 9.9e-05 22.6 0.1 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG22344.1 - 0.0013 18.6 0.0 1.3 8.8 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAG22344.1 - 0.091 11.7 3.7 0.044 12.7 0.6 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4487 PF14868.6 OAG22345.1 - 0.014 14.2 0.6 0.022 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) TP6A_N PF04406.14 OAG22347.1 - 4.9e-21 74.5 1.2 1e-20 73.5 0.3 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase CAF1A PF12253.8 OAG22348.1 - 2.6e-23 82.0 8.8 2.6e-23 82.0 8.8 2.8 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 OAG22348.1 - 0.00068 19.4 36.3 0.0013 18.4 36.3 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal COPI_C PF06957.11 OAG22348.1 - 0.0017 17.2 1.8 0.0017 17.2 1.8 2.0 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus Borrelia_P83 PF05262.11 OAG22348.1 - 0.41 9.1 26.4 0.63 8.5 26.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 OAG22348.1 - 0.43 10.3 30.2 0.052 13.4 23.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 OAG22348.1 - 0.66 8.7 15.0 1.5 7.5 15.0 1.5 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.9 OAG22348.1 - 0.96 9.0 32.5 2.1 7.9 32.5 1.5 1 0 0 1 1 1 0 DDRGK domain Tho2 PF11262.8 OAG22348.1 - 1.4 8.1 16.0 2.2 7.4 16.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LCD1 PF09798.9 OAG22348.1 - 1.8 7.0 11.3 2.4 6.6 11.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein RPOL_N PF14700.6 OAG22348.1 - 3.4 7.0 20.2 8.3 5.7 0.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal SLC12 PF03522.15 OAG22348.1 - 4.4 6.2 17.4 7.4 5.5 17.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 OAG22348.1 - 7.3 5.7 9.7 14 4.7 9.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Asp PF00026.23 OAG22349.1 - 2.4e-10 40.4 1.7 4.9e-10 39.3 1.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.20 OAG22349.1 - 0.044 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain VRP1 PF03538.14 OAG22349.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein HET PF06985.11 OAG22350.1 - 3.6e-29 102.0 0.5 6.1e-29 101.3 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonucleas_3_3 PF14622.6 OAG22351.1 - 1.4e-27 96.4 0.0 3.4e-27 95.1 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG22351.1 - 9.3e-06 26.2 0.0 0.00022 21.8 0.0 2.9 2 2 1 3 3 3 1 Ribonuclease III domain HAT_KAT11 PF08214.11 OAG22352.1 - 4.2e-102 342.0 0.0 5.9e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.6 OAG22353.1 - 4.4e-12 45.8 0.0 0.00019 20.9 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAG22353.1 - 1.8e-09 37.8 0.0 4.1e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG22353.1 - 0.0017 18.2 0.0 0.02 14.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Aldo_ket_red PF00248.21 OAG22354.1 - 1.6e-69 234.4 0.0 1.9e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG22355.1 - 1.1e-21 77.1 19.2 1.7e-21 76.5 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 OAG22356.1 - 1.7e-52 178.9 0.0 2.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TrkH PF02386.16 OAG22357.1 - 1.4e-146 488.9 4.8 1.4e-146 488.9 4.8 2.0 2 0 0 2 2 2 2 Cation transport protein Glycogen_syn PF05693.13 OAG22358.1 - 0 1125.8 0.0 0 1125.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAG22358.1 - 4.8e-06 26.2 0.0 0.0081 15.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG22358.1 - 0.00016 21.7 0.2 0.00032 20.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAG22358.1 - 0.00023 21.6 0.0 0.18 12.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG22358.1 - 0.00031 21.2 0.0 0.00059 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 OAG22358.1 - 0.00086 19.1 0.1 0.0026 17.5 0.1 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain PH PF00169.29 OAG22359.1 - 1e-07 32.4 0.3 2.5e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 PH domain DUF572 PF04502.13 OAG22359.1 - 0.27 10.8 20.4 0.013 15.2 14.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) BAF1_ABF1 PF04684.13 OAG22359.1 - 0.64 9.0 15.8 1.4 7.9 15.8 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.7 OAG22361.1 - 9.5e-06 25.4 0.0 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF1604 PF07713.13 OAG22361.1 - 0.14 12.0 0.4 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) F-box PF00646.33 OAG22361.1 - 0.15 12.0 0.0 0.52 10.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain zf-RanBP PF00641.18 OAG22363.1 - 1.4e-20 72.3 11.1 1.5e-10 40.2 2.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 OAG22363.1 - 1.1e-07 31.6 0.0 2.9e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 OAG22363.1 - 4.5e-06 27.3 0.0 6.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DZR PF12773.7 OAG22363.1 - 5.4 7.1 7.3 4.6 7.3 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Mannosyl_trans3 PF11051.8 OAG22364.1 - 4.7e-60 203.3 0.0 2.6e-36 125.4 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG22364.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Cnd3 PF12719.7 OAG22365.1 - 2.3e-83 279.8 0.5 1e-82 277.7 0.2 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 OAG22365.1 - 5.1e-10 38.7 1.7 0.071 13.4 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OAG22365.1 - 2.2e-06 27.9 6.9 0.0026 18.1 0.8 4.6 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 OAG22365.1 - 0.00047 20.2 3.7 0.92 9.5 0.0 4.8 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG22365.1 - 0.007 16.8 1.9 3.1 8.4 0.1 4.3 3 1 1 4 4 4 2 HEAT-like repeat CLASP_N PF12348.8 OAG22365.1 - 0.035 13.7 0.0 0.3 10.6 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAG22365.1 - 0.097 13.3 0.0 0.62 10.7 0.0 2.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 OAG22365.1 - 0.11 12.9 1.5 28 5.1 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PALP PF00291.25 OAG22366.1 - 1.5e-66 224.9 0.1 1.7e-66 224.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUDIX PF00293.28 OAG22367.1 - 4.9e-16 59.0 0.4 1.1e-15 57.8 0.4 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAG22367.1 - 1.3e-15 57.9 0.0 8e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAG22367.1 - 0.00012 21.6 1.2 0.00029 20.4 1.2 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain ChlI PF13541.6 OAG22367.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase COG2 PF06148.11 OAG22368.1 - 9.1e-33 113.2 0.6 9.1e-33 113.2 0.6 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OAG22368.1 - 0.00049 20.1 0.1 0.0013 18.8 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Zw10 PF06248.13 OAG22368.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Pox_Ag35 PF03286.14 OAG22368.1 - 0.66 9.7 4.3 6.2 6.6 0.1 2.8 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Ribosomal_L1 PF00687.21 OAG22369.1 - 2.2e-30 105.9 0.1 4.2e-30 105.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_3 PF13302.7 OAG22370.1 - 1.4e-17 64.7 0.0 1.8e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG22370.1 - 0.016 15.4 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 OAG22372.1 - 1e-28 100.3 29.5 1e-28 100.3 29.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Lipase_GDSL PF00657.22 OAG22373.1 - 1.5e-08 34.9 0.4 1.9e-08 34.5 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG22373.1 - 1.3e-05 25.7 0.0 2.3e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PKD_3 PF16820.5 OAG22373.1 - 0.089 12.5 0.1 10 6.0 0.0 2.9 3 0 0 3 3 3 0 PKD-like domain HET PF06985.11 OAG22374.1 - 1.1e-29 103.7 3.9 1.6e-26 93.4 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ABC_tran_2 PF16949.5 OAG22374.1 - 0.13 11.1 0.3 0.19 10.5 0.3 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette Scramblase PF03803.15 OAG22375.1 - 2.3e-52 177.5 0.0 3.8e-29 101.6 0.0 2.9 1 1 1 2 2 2 2 Scramblase tRNA_int_endo PF01974.17 OAG22376.1 - 9.5e-19 67.3 0.2 4.9e-17 61.8 0.5 2.9 2 1 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAG22376.1 - 0.00073 19.2 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Asn_synthase PF00733.21 OAG22377.1 - 5.7e-76 256.5 0.0 8e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 OAG22377.1 - 1.6e-34 118.4 0.0 4.7e-34 116.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAG22377.1 - 7.7e-31 107.1 0.0 1.5e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG22377.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein NPP1 PF05630.11 OAG22379.1 - 4.5e-66 222.7 0.1 5.2e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) RskA PF10099.9 OAG22380.1 - 7.4 6.8 11.9 2.5 8.3 1.3 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF5597 PF18120.1 OAG22381.1 - 1.6e-24 86.5 0.0 2.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 OAG22381.1 - 1.1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 OAG22381.1 - 4.4e-07 29.8 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 NmrA PF05368.13 OAG22382.1 - 1.8e-52 178.2 0.0 2.2e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG22382.1 - 1.3e-13 51.3 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG22382.1 - 0.00075 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG22382.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SQHop_cyclase_C PF13243.6 OAG22383.1 - 1.5e-47 162.2 2.3 1.6e-45 155.6 1.4 2.8 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAG22383.1 - 7.2e-39 133.6 10.1 3.5e-34 118.2 1.7 4.1 3 2 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAG22383.1 - 1.1e-27 95.5 4.2 3.8e-09 36.1 0.0 4.6 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAG22383.1 - 0.00056 19.0 0.6 0.0071 15.4 0.0 2.7 2 1 1 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 OAG22383.1 - 0.0029 17.0 0.6 3.8 6.8 0.0 4.7 5 1 1 6 6 6 1 Pectic acid lyase DUF1295 PF06966.12 OAG22385.1 - 1e-15 57.9 0.1 1.4e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAG22385.1 - 4.3e-09 35.6 0.8 6e-09 35.2 0.8 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 OAG22385.1 - 0.00035 20.6 0.2 0.00044 20.3 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.11 OAG22385.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 1 0 1 1 1 0 NnrU protein ICMT PF04140.14 OAG22385.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DNA_ligase_A_M PF01068.21 OAG22386.1 - 9.5e-24 84.2 0.0 2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG22386.1 - 2.2e-21 76.9 0.0 4.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus Vps54 PF07928.12 OAG22387.1 - 2.1e-47 160.9 0.3 6.1e-47 159.4 0.3 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 OAG22387.1 - 0.00071 18.9 0.2 0.00071 18.9 0.2 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 OAG22387.1 - 0.02 14.7 1.4 3.3 7.6 0.0 3.2 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Sigma_reg_N PF13800.6 OAG22392.1 - 0.0018 18.5 0.5 0.013 15.7 1.1 2.3 2 0 0 2 2 2 1 Sigma factor regulator N-terminal MASE1 PF05231.14 OAG22392.1 - 0.0066 15.6 6.0 0.0066 15.6 6.0 1.7 2 0 0 2 2 2 1 MASE1 DUF1129 PF06570.11 OAG22392.1 - 0.016 14.7 1.1 0.027 14.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GPDPase_memb PF10110.9 OAG22392.1 - 0.095 11.5 4.8 0.14 10.9 4.8 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase ABC_export PF16962.5 OAG22392.1 - 0.17 10.3 3.7 0.26 9.7 3.7 1.3 1 0 0 1 1 1 0 Putative ABC exporter DUF2189 PF09955.9 OAG22392.1 - 0.37 11.0 5.8 0.39 11.0 0.1 2.4 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) GWT1 PF06423.12 OAG22392.1 - 2.6 8.1 8.0 6.6 6.8 2.8 2.3 1 1 1 2 2 2 0 GWT1 Syntaxin-6_N PF09177.11 OAG22393.1 - 7.3e-27 93.8 1.8 1.6e-26 92.7 0.3 2.2 2 1 1 3 3 2 1 Syntaxin 6, N-terminal HMMR_N PF15905.5 OAG22393.1 - 0.0015 18.1 1.3 0.0015 18.1 1.3 1.7 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 OAG22393.1 - 0.0016 18.4 1.3 0.091 12.8 0.4 2.1 2 0 0 2 2 2 1 Laminin Domain II Mer2 PF09074.10 OAG22393.1 - 0.0043 16.9 1.3 0.0079 16.0 1.3 1.4 1 1 0 1 1 1 1 Mer2 SNARE PF05739.19 OAG22393.1 - 0.0067 16.4 4.6 0.033 14.2 0.2 2.9 3 0 0 3 3 3 1 SNARE domain YtxH PF12732.7 OAG22393.1 - 0.01 16.3 1.5 3 8.4 0.1 2.9 1 1 0 2 2 2 0 YtxH-like protein Prominin PF05478.11 OAG22393.1 - 0.011 13.7 0.3 0.14 10.0 0.3 2.0 1 1 0 1 1 1 0 Prominin DUF4795 PF16043.5 OAG22393.1 - 0.018 14.6 2.9 0.02 14.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) STAT_alpha PF01017.20 OAG22393.1 - 0.025 14.5 0.3 0.025 14.5 0.3 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain FapA PF03961.13 OAG22393.1 - 0.032 12.8 0.6 0.044 12.4 0.4 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 OAG22393.1 - 0.045 12.8 0.0 0.087 11.9 0.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OAG22393.1 - 0.073 13.1 5.2 1 9.4 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 OAG22393.1 - 0.086 13.1 3.7 16 5.8 0.1 3.4 4 0 0 4 4 3 0 Proteins of 100 residues with WXG AKNA PF12443.8 OAG22393.1 - 0.093 13.4 5.3 0.11 13.1 0.1 2.5 2 1 1 3 3 2 0 AT-hook-containing transcription factor DUF2205 PF10224.9 OAG22393.1 - 0.093 12.7 0.2 0.093 12.7 0.2 2.7 3 0 0 3 3 3 0 Short coiled-coil protein KxDL PF10241.9 OAG22393.1 - 0.095 13.0 2.9 9 6.7 0.1 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein Fez1 PF06818.15 OAG22393.1 - 0.11 12.9 4.2 0.17 12.3 4.2 1.3 1 0 0 1 1 1 0 Fez1 Sugar-bind PF04198.13 OAG22393.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DUF883 PF05957.13 OAG22393.1 - 0.14 12.8 6.0 2.3 8.9 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3618 PF12277.8 OAG22393.1 - 0.15 12.3 5.6 28 5.1 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) Syntaxin_2 PF14523.6 OAG22393.1 - 0.18 12.2 1.1 0.58 10.6 1.1 1.9 1 1 0 1 1 1 0 Syntaxin-like protein RRF PF01765.19 OAG22393.1 - 0.21 11.5 4.6 3.2 7.7 1.7 2.8 2 1 1 3 3 3 0 Ribosome recycling factor Spc7 PF08317.11 OAG22393.1 - 0.22 10.4 6.2 0.092 11.6 1.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 OAG22393.1 - 0.35 11.2 8.7 1.2 9.5 3.0 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 OAG22393.1 - 0.54 10.3 4.7 1.9 8.6 2.0 2.7 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GAS PF13851.6 OAG22393.1 - 0.58 9.5 5.5 0.29 10.5 1.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 OAG22393.1 - 0.63 10.1 4.5 0.88 9.6 0.8 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GCIP PF13324.6 OAG22393.1 - 0.8 9.3 7.2 0.59 9.7 3.0 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Pox_EPC_I2-L1 PF12575.8 OAG22393.1 - 1.3 9.3 3.8 11 6.3 0.8 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 NPV_P10 PF05531.12 OAG22393.1 - 1.4 9.5 5.5 18 5.9 0.2 3.1 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 OAG22393.1 - 1.5 7.6 7.9 1.3 7.8 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DotU PF09850.9 OAG22393.1 - 1.6 8.4 7.9 0.8 9.4 0.1 3.2 2 2 2 4 4 4 0 Type VI secretion system protein DotU Tropomyosin_1 PF12718.7 OAG22393.1 - 2.2 8.4 10.9 6.5 6.9 0.6 2.7 1 1 2 3 3 3 0 Tropomyosin like YabA PF06156.13 OAG22393.1 - 2.3 8.9 7.1 2.7 8.7 2.8 2.5 2 1 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 OAG22393.1 - 2.7 8.5 12.5 8.2 7.0 5.1 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Rx_N PF18052.1 OAG22393.1 - 2.8 8.3 7.5 2.4 8.5 2.6 2.5 1 1 1 2 2 2 0 Rx N-terminal domain UPF0242 PF06785.11 OAG22393.1 - 4.4 7.4 15.4 0.26 11.4 1.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_32 PF13679.6 OAG22394.1 - 1.3e-22 80.5 2.5 2.4e-21 76.3 2.5 2.2 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_S41 PF03572.18 OAG22395.1 - 1.7e-09 37.5 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Asp PF00026.23 OAG22396.1 - 0.026 13.9 0.0 0.096 12.1 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Glyco_hydro_72 PF03198.14 OAG22397.1 - 3.4e-119 397.8 2.3 4.1e-119 397.5 2.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAG22397.1 - 0.0016 17.9 2.0 0.005 16.3 2.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SGS PF05002.15 OAG22398.1 - 2.2e-29 101.4 0.8 4.6e-29 100.4 0.8 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OAG22398.1 - 7.2e-17 62.2 0.1 1.5e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 OAG22398.1 - 4.7e-11 42.0 1.4 5.7e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22398.1 - 1.5e-08 34.1 5.2 0.0037 17.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22398.1 - 4.2e-08 33.7 5.7 0.00015 22.4 0.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22398.1 - 1.9e-05 24.9 3.0 0.0059 16.9 1.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22398.1 - 0.0001 21.9 0.7 0.00022 20.8 0.2 1.8 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 OAG22398.1 - 0.0026 17.9 2.8 0.085 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22398.1 - 0.0032 18.2 0.5 0.87 10.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG22398.1 - 0.0039 17.7 0.7 0.73 10.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAG22398.1 - 0.012 15.6 1.2 0.021 14.8 1.2 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat DUF3856 PF12968.7 OAG22398.1 - 0.035 14.2 0.8 0.11 12.5 0.8 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 OAG22398.1 - 0.053 13.6 0.2 3.1 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG22398.1 - 0.24 11.9 0.8 9.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Questin_oxidase PF14027.6 OAG22399.1 - 4.9e-103 345.2 1.3 5.9e-103 345.0 1.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3848 PF12959.7 OAG22399.1 - 0.019 15.0 0.9 0.068 13.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) DUF1996 PF09362.10 OAG22400.1 - 3.3e-84 282.5 1.4 4.5e-84 282.1 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM64 PF18666.1 OAG22400.1 - 0.07 13.2 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 64 BCS1_N PF08740.11 OAG22401.1 - 3e-35 121.9 0.1 4.8e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG22401.1 - 1e-14 55.1 0.0 7.1e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG22401.1 - 0.0036 17.3 0.0 0.019 15.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG22401.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG22401.1 - 0.036 14.5 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OAG22401.1 - 0.051 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 OAG22401.1 - 0.17 11.6 1.5 9 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 OAG22401.1 - 0.21 11.3 0.7 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain GDPD_2 PF13653.6 OAG22403.1 - 0.86 10.1 5.0 0.61 10.6 1.0 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PQ-loop PF04193.14 OAG22404.1 - 2.1e-40 136.3 12.7 1.5e-20 72.7 4.6 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF2967 PF11179.8 OAG22405.1 - 3.1 5.8 5.9 4.3 5.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF962 PF06127.11 OAG22406.1 - 4.4e-25 87.6 0.5 6.7e-25 87.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Ntox4 PF15541.6 OAG22406.1 - 0.0077 16.6 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial toxin 4 ABC_membrane PF00664.23 OAG22406.1 - 0.089 12.4 0.4 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Sugar_tr PF00083.24 OAG22407.1 - 7.5e-77 259.1 22.4 1.2e-74 251.9 22.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22407.1 - 1.6e-12 47.0 31.9 2.1e-06 26.9 9.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Gtr1_RagA PF04670.12 OAG22409.1 - 5.5e-94 313.9 0.1 7e-94 313.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG22409.1 - 7.7e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG22409.1 - 9.6e-08 31.8 0.6 1.9e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Ras family Arf PF00025.21 OAG22409.1 - 3.9e-07 29.7 0.0 7.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG22409.1 - 1.5e-06 28.3 0.0 3.7e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.13 OAG22409.1 - 0.0024 17.1 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 OAG22409.1 - 0.0027 17.3 0.0 0.0072 15.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG22409.1 - 0.016 15.1 0.1 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 OAG22409.1 - 0.021 15.3 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OAG22409.1 - 0.043 13.6 0.3 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.20 OAG22409.1 - 0.076 12.2 4.1 2.7 7.1 0.0 2.9 2 1 1 3 3 3 0 G-protein alpha subunit DUF1688 PF07958.11 OAG22410.1 - 6.4e-185 614.8 0.0 7.2e-185 614.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_2 PF07719.17 OAG22411.1 - 4.2e-05 23.3 1.9 4.7 7.6 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG22411.1 - 7.2e-05 22.4 1.3 0.74 9.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 OAG22411.1 - 0.069 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 DnaJ domain Fungal_trans PF04082.18 OAG22412.1 - 2.3e-11 43.2 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22412.1 - 0.0001 22.4 10.3 0.00019 21.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.26 OAG22413.1 - 1.8e-12 47.1 4.4 3.7e-12 46.1 4.4 1.5 1 0 0 1 1 1 1 WW domain WRW PF10206.9 OAG22413.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_2 PF12796.7 OAG22414.1 - 3.4e-23 82.0 2.4 2.8e-15 56.7 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG22414.1 - 8.4e-20 70.9 0.2 2.2e-14 53.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG22414.1 - 8.4e-16 57.6 1.4 1.8e-08 34.4 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG22414.1 - 6.6e-13 48.6 2.2 1.6e-07 31.5 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG22414.1 - 8.5e-13 47.3 0.2 9e-06 25.7 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat PipA PF07108.11 OAG22414.1 - 0.0031 17.1 0.4 0.0046 16.5 0.4 1.2 1 0 0 1 1 1 1 PipA protein Not3 PF04065.15 OAG22414.1 - 0.14 11.6 0.6 0.61 9.5 0.2 1.9 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Tudor_3 PF18115.1 OAG22415.1 - 1.1e-16 60.3 0.0 2.8e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 OAG22415.1 - 2.1e-14 53.8 0.0 4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 OAG22415.1 - 3.8e-08 33.6 0.0 2e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG22415.1 - 0.0016 18.8 0.0 0.0048 17.3 0.0 1.9 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAG22415.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain NQRA PF05896.11 OAG22415.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Sdh_cyt PF01127.22 OAG22416.1 - 1.9e-24 86.0 3.6 2.4e-24 85.7 3.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit WD40 PF00400.32 OAG22417.1 - 3.3e-08 34.0 3.7 0.074 14.0 0.1 4.5 4 1 1 5 5 5 3 WD domain, G-beta repeat AAA_22 PF13401.6 OAG22420.1 - 0.0018 18.5 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAG22420.1 - 0.015 15.4 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF853 PF05872.12 OAG22420.1 - 0.031 12.9 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAD_binding_4 PF01565.23 OAG22421.1 - 3.6e-22 78.6 0.9 6.5e-22 77.8 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG22421.1 - 0.0081 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like BRO1 PF03097.18 OAG22421.1 - 0.039 12.8 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF2269 PF10027.9 OAG22422.1 - 0.97 9.5 9.1 0.069 13.2 3.6 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Glyco_hydro_31 PF01055.26 OAG22424.1 - 2.4e-138 462.0 9.2 3.9e-138 461.3 9.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG22424.1 - 4.1e-25 87.9 0.7 8.6e-24 83.6 0.2 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAG22424.1 - 1.2e-07 31.9 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 OAG22425.1 - 2.6e-53 179.7 0.0 2.9e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase POT1 PF02765.17 OAG22426.1 - 1.2e-08 34.9 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Amidase PF01425.21 OAG22427.1 - 6.8e-57 193.4 0.0 9.4e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG22428.1 - 1.3e-26 93.3 36.7 4.2e-26 91.7 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 OAG22428.1 - 0.00044 19.2 1.1 0.00044 19.2 1.1 1.7 2 0 0 2 2 2 1 POT family PBP PF01161.20 OAG22429.1 - 1.1e-14 54.9 0.0 1.4e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HRDC PF00570.23 OAG22430.1 - 1.5e-20 72.9 0.1 8.9e-14 51.2 0.1 2.5 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.20 OAG22430.1 - 2.2e-16 60.0 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.23 OAG22430.1 - 0.01 15.7 0.1 3.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DEAD PF00270.29 OAG22431.1 - 4.3e-18 65.7 0.0 9.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG22431.1 - 6.5e-13 49.0 0.1 6.7e-12 45.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG22431.1 - 1.2e-06 28.9 0.0 3.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRIMA1 PF16101.5 OAG22432.1 - 0.022 14.8 3.2 0.023 14.7 3.2 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 OAG22432.1 - 0.12 12.4 2.2 0.12 12.5 2.2 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OAG22432.1 - 0.12 11.8 2.1 0.13 11.7 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TAF PF02969.17 OAG22433.1 - 1.8e-23 82.5 0.1 8.8e-23 80.3 0.1 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OAG22433.1 - 1.6e-22 79.6 0.1 4.4e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 OAG22433.1 - 0.0051 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAG22433.1 - 0.025 14.7 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1778 PF08681.11 OAG22433.1 - 0.033 14.1 1.1 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1778) Bromo_TP PF07524.13 OAG22433.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 OAG22433.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC2_membrane PF01061.24 OAG22435.1 - 5.7e-79 264.4 52.2 2.5e-40 138.1 16.7 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG22435.1 - 1.9e-35 122.4 0.0 2.9e-16 60.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 OAG22435.1 - 5.2e-26 90.4 8.6 5.6e-22 77.5 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG22435.1 - 7.8e-17 61.7 0.1 2.3e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG22435.1 - 2.2e-08 33.6 33.2 1.7e-07 30.7 12.6 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAG22435.1 - 1.5e-05 25.0 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG22435.1 - 2.5e-05 24.7 0.0 0.0079 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG22435.1 - 3.1e-05 24.2 0.1 0.027 14.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG22435.1 - 6.3e-05 23.5 0.0 0.053 14.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG22435.1 - 0.00014 21.6 0.5 0.014 15.1 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG22435.1 - 0.00041 20.3 0.1 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAG22435.1 - 0.00049 19.7 0.0 0.028 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG22435.1 - 0.0064 16.2 0.3 0.31 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG22435.1 - 0.011 15.1 0.1 1.1 8.7 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 OAG22435.1 - 0.017 15.6 0.8 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG22435.1 - 0.017 15.4 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAG22435.1 - 0.025 14.3 0.7 6.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OAG22435.1 - 0.031 14.2 0.4 5.5 6.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAG22435.1 - 0.043 14.0 0.6 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG22435.1 - 0.051 13.2 1.4 0.47 10.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OAG22435.1 - 0.096 13.1 0.2 42 4.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 OAG22435.1 - 0.14 12.6 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAG22435.1 - 0.23 11.8 0.3 27 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG22435.1 - 0.53 10.8 0.0 0.53 10.8 0.0 3.1 4 0 0 4 4 3 0 AAA domain Opi1 PF08618.10 OAG22438.1 - 1.3e-34 120.2 20.0 4.5e-24 85.5 7.8 3.8 2 1 2 4 4 4 3 Transcription factor Opi1 Peptidase_S64 PF08192.11 OAG22438.1 - 0.38 9.2 1.9 0.55 8.7 1.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 ELO PF01151.18 OAG22439.1 - 5e-62 209.7 17.2 5.9e-62 209.4 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family B56 PF01603.20 OAG22440.1 - 4.9e-193 641.8 6.1 5.8e-193 641.5 6.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 OAG22440.1 - 0.00044 20.2 1.5 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SOG2 PF10428.9 OAG22440.1 - 1.5 7.9 12.4 15 4.6 0.0 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Tau95 PF09734.9 OAG22441.1 - 4.4e-34 118.3 0.3 4.4e-34 118.3 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OAG22441.1 - 7.5e-33 113.4 0.7 1.2e-32 112.8 0.0 1.7 2 0 0 2 2 2 1 Tau95 Triple barrel domain Astro_capsid_p PF12226.8 OAG22441.1 - 3.5 6.7 22.2 5.8 6.0 22.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COX5A PF02284.16 OAG22442.1 - 8.7e-41 138.1 0.2 1.1e-40 137.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Scm3 PF10384.9 OAG22442.1 - 0.081 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 FAT PF02259.23 OAG22443.1 - 2.7e-73 247.2 7.1 5.7e-73 246.1 7.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAG22443.1 - 2.8e-34 119.1 0.0 7.6e-34 117.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAG22443.1 - 0.0045 16.8 0.1 0.015 15.1 0.1 2.0 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.6 OAG22443.1 - 0.19 12.0 2.3 0.8 10.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 OAG22444.1 - 3.1e-29 102.1 8.2 4e-29 101.7 8.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 OAG22444.1 - 4.5e-05 23.4 16.9 6.2e-05 22.9 6.8 3.1 1 1 1 2 2 2 2 Pectate lyase superfamily protein E1-E2_ATPase PF00122.20 OAG22446.1 - 8.6e-34 116.6 23.3 3e-29 101.8 0.3 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG22446.1 - 6.2e-22 78.2 8.8 6.2e-22 78.2 8.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAG22446.1 - 9.4e-17 60.9 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG22446.1 - 6e-16 59.4 0.0 1.9e-14 54.5 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG22446.1 - 1.8e-15 56.4 0.1 1.3e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG22446.1 - 0.00067 19.5 0.4 0.0041 16.9 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4089 PF13318.6 OAG22446.1 - 0.1 13.1 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) zf-rbx1 PF12678.7 OAG22447.1 - 3e-09 37.0 1.0 6.1e-08 32.8 0.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG22447.1 - 2.1e-08 34.4 3.3 1.2e-06 28.8 1.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAG22447.1 - 1.6e-06 27.8 3.4 4.5e-05 23.2 1.2 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG22447.1 - 9e-06 25.7 0.1 2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG22447.1 - 1.8e-05 24.5 3.7 0.00024 20.9 0.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG22447.1 - 0.00014 21.6 4.2 0.06 13.1 0.1 3.2 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_UBOX PF13445.6 OAG22447.1 - 0.0033 17.4 5.8 0.27 11.3 0.0 3.4 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG22447.1 - 0.0037 17.1 0.2 0.0037 17.1 0.2 2.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG22447.1 - 0.0043 16.9 5.6 0.043 13.7 0.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG22447.1 - 0.023 14.3 0.5 0.023 14.3 0.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD_4 PF16866.5 OAG22447.1 - 0.062 13.4 1.1 34 4.6 0.0 3.6 4 0 0 4 4 4 0 PHD-finger FANCL_C PF11793.8 OAG22447.1 - 0.072 13.3 3.7 0.49 10.6 2.0 2.8 2 1 1 3 3 3 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OAG22447.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OAG22447.1 - 0.59 10.1 5.8 0.14 12.2 0.5 2.5 3 0 0 3 3 3 0 zinc-RING finger domain zf-met PF12874.7 OAG22447.1 - 1.2 9.7 2.8 0.77 10.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RINGv PF12906.7 OAG22447.1 - 1.8 8.8 4.9 0.72 10.0 1.5 2.0 2 0 0 2 2 2 0 RING-variant domain Fungal_trans PF04082.18 OAG22448.1 - 3.2e-30 105.1 0.3 8.6e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22448.1 - 0.00027 21.0 2.3 0.00027 21.0 2.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 OAG22449.1 - 3.3e-13 50.0 0.0 3e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG22449.1 - 2.5e-10 40.2 0.0 6.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 OAG22449.1 - 3.8e-05 22.5 0.0 0.04 12.6 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.28 OAG22449.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 OAG22449.1 - 0.0013 18.1 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OAG22449.1 - 0.005 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OAG22449.1 - 0.034 13.8 0.1 0.077 12.6 0.1 1.6 1 1 0 1 1 1 0 Putative esterase ubiquitin PF00240.23 OAG22450.1 - 2.8e-25 87.9 0.0 3.1e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG22450.1 - 5.2e-16 58.2 0.1 5.7e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG22450.1 - 7.1e-05 23.2 0.0 0.0002 21.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG22450.1 - 0.0062 16.4 0.0 0.0074 16.2 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG22450.1 - 0.041 14.0 0.0 0.096 12.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Adeno_PX PF05829.12 OAG22452.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Flot PF15975.5 OAG22452.1 - 2 8.6 5.8 0.32 11.2 0.6 2.1 2 0 0 2 2 2 0 Flotillin RabGAP-TBC PF00566.18 OAG22453.1 - 3.3e-32 111.9 0.0 5.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lactamase_B PF00753.27 OAG22454.1 - 3.1e-13 50.2 8.1 4.1e-13 49.8 8.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG22454.1 - 0.00017 21.2 0.6 0.00031 20.3 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OAG22454.1 - 0.045 13.2 0.3 7.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain EHN PF06441.12 OAG22455.1 - 6.8e-34 116.5 1.3 1.2e-33 115.7 1.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG22455.1 - 3.1e-08 33.6 0.0 5.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold NFACT-C PF11923.8 OAG22456.1 - 8.4e-40 135.0 0.1 8.4e-40 135.0 0.1 3.8 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 OAG22456.1 - 3.1e-33 115.2 11.2 3.1e-33 115.2 11.2 2.5 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OAG22456.1 - 1.5e-28 99.6 0.0 3.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF4255 PF14065.6 OAG22456.1 - 0.049 13.3 0.1 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) Clat_adaptor_s PF01217.20 OAG22457.1 - 6.2e-14 52.1 0.5 1.3e-13 51.1 0.5 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF3433 PF11915.8 OAG22459.1 - 4.3e-14 52.7 0.6 4.3e-14 52.7 0.6 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF2207 PF09972.9 OAG22459.1 - 0.0089 14.8 0.2 0.055 12.2 0.0 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF1682 PF07946.14 OAG22461.1 - 0.3 10.2 9.7 0.56 9.4 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MFS_1 PF07690.16 OAG22463.1 - 6.6e-32 110.8 39.4 6.6e-32 110.8 39.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Pectinesterase PF01095.19 OAG22464.1 - 8.5e-130 431.8 50.9 3.3e-45 154.1 4.4 5.5 5 2 0 5 5 5 4 Pectinesterase Hexokinase_2 PF03727.16 OAG22465.1 - 5.2e-82 274.9 0.0 6.8e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG22465.1 - 3.6e-71 239.2 0.0 5.1e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DAO PF01266.24 OAG22466.1 - 4e-38 131.9 1.8 5e-38 131.6 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG22466.1 - 0.00017 21.8 0.1 0.00037 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG22466.1 - 0.00058 19.2 0.0 0.0057 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG22466.1 - 0.0015 17.9 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-CDGSH PF09360.10 OAG22466.1 - 0.057 13.6 0.4 0.16 12.2 0.4 1.8 1 0 0 1 1 1 0 Iron-binding zinc finger CDGSH type NAD_binding_9 PF13454.6 OAG22466.1 - 0.058 13.4 0.4 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG22466.1 - 0.061 12.6 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 OAG22466.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 OAG22466.1 - 0.15 10.7 0.3 9.1 4.9 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Hydrolase PF00702.26 OAG22467.1 - 5.6e-07 30.1 0.0 4.2e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG22467.1 - 0.0011 19.1 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CagY_M PF07337.11 OAG22467.1 - 0.048 13.3 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 DC-EC Repeat RPAP1_C PF08620.10 OAG22467.1 - 0.16 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 RPAP1-like, C-terminal Fungal_trans PF04082.18 OAG22468.1 - 5.9e-17 61.6 0.1 9.9e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22468.1 - 2.5e-06 27.5 12.5 5.1e-06 26.5 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 OAG22469.1 - 1.6e-47 162.8 0.2 1.8e-47 162.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG22469.1 - 0.026 13.7 2.7 0.8 8.9 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG22469.1 - 0.1 12.6 2.7 0.21 11.6 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG22469.1 - 0.19 11.0 0.5 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG22469.1 - 0.44 9.2 0.0 0.44 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 OAG22470.1 - 4.8e-10 38.9 38.2 4.8e-10 38.9 38.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG22470.1 - 0.00015 21.5 4.0 0.00015 21.5 4.0 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 OAG22470.1 - 0.00066 18.8 1.7 0.00066 18.8 1.7 2.0 2 1 1 3 3 3 1 PUCC protein adh_short PF00106.25 OAG22471.1 - 4.6e-23 81.7 0.0 2.7e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22471.1 - 4.7e-11 42.7 0.0 9.4e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22471.1 - 5.8e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG22471.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG22471.1 - 0.031 13.7 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF478 PF04334.12 OAG22471.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF478) Cyclase PF04199.13 OAG22474.1 - 5e-15 55.9 0.0 1.2e-14 54.7 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase AsiA PF09010.10 OAG22474.1 - 0.0014 18.6 0.1 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Anti-Sigma Factor A RabGAP-TBC PF00566.18 OAG22475.1 - 4e-50 170.5 0.0 4.2e-48 163.9 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3220 PF11516.8 OAG22475.1 - 0.022 15.0 0.4 0.62 10.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3120) RRM_1 PF00076.22 OAG22476.1 - 1.6e-31 107.9 0.2 3.6e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG22476.1 - 6.6e-11 42.2 0.1 0.00048 20.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAG22476.1 - 0.022 14.7 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG22476.1 - 0.048 13.7 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif TMEM156 PF15106.6 OAG22476.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family Glyco_hydro_16 PF00722.21 OAG22477.1 - 6e-43 146.4 2.2 9e-43 145.8 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Aldedh PF00171.22 OAG22478.1 - 5.9e-10 38.2 8.6 0.00019 20.1 5.2 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 OAG22479.1 - 5.9e-09 35.7 0.0 8.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG22479.1 - 5.9e-09 36.0 0.0 3.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG22479.1 - 0.00061 19.1 0.1 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG22479.1 - 0.0025 17.1 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG22479.1 - 0.0061 15.9 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG22479.1 - 0.012 14.9 0.6 0.018 14.3 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG22479.1 - 0.025 14.6 0.5 0.27 11.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 OAG22479.1 - 0.029 14.0 0.1 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG22479.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG22479.1 - 0.039 12.7 0.0 0.17 10.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OAG22479.1 - 0.043 14.1 0.0 0.2 11.9 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.12 OAG22479.1 - 0.21 10.6 0.8 0.26 10.3 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.16 OAG22480.1 - 2.7e-28 99.2 22.5 3.6e-28 98.8 22.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG22480.1 - 0.01 15.1 23.4 0.043 13.0 23.4 1.8 1 1 0 1 1 1 0 UAA transporter family EamA PF00892.20 OAG22480.1 - 0.01 16.0 14.7 0.01 16.0 14.7 2.7 3 0 0 3 3 3 0 EamA-like transporter family Ribosomal_L18 PF17135.4 OAG22481.1 - 9.3e-91 302.3 2.8 1e-90 302.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAG22481.1 - 3.9e-05 24.3 0.6 3.9e-05 24.3 0.6 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AIRC PF00731.20 OAG22482.1 - 1.6e-56 190.0 0.2 3.6e-56 188.9 0.0 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 OAG22482.1 - 3.9e-53 179.5 0.0 6.5e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 OAG22482.1 - 3.8e-18 64.9 0.0 9.1e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AlaDh_PNT_C PF01262.21 OAG22482.1 - 5.6e-05 22.5 0.7 0.00013 21.4 0.7 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_D2 PF02786.17 OAG22482.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 OAG22482.1 - 0.00066 19.3 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 OAG22482.1 - 0.0016 17.9 0.1 0.0032 16.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG22482.1 - 0.0023 17.9 0.3 0.0056 16.6 0.3 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 OAG22482.1 - 0.0076 16.3 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain NAD_binding_2 PF03446.15 OAG22482.1 - 0.032 14.4 0.2 0.082 13.1 0.2 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Radical_SAM PF04055.21 OAG22482.1 - 0.038 14.4 0.0 18 5.7 0.0 3.0 2 1 0 2 2 2 0 Radical SAM superfamily XdhC_C PF13478.6 OAG22482.1 - 0.038 14.5 0.1 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain SRR1 PF07985.12 OAG22483.1 - 1.7e-15 56.8 0.0 2.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 Synuclein PF01387.17 OAG22483.1 - 0.0011 19.2 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 Synuclein RRP7 PF12923.7 OAG22483.1 - 0.085 13.0 3.9 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Botulinum_HA-17 PF05588.11 OAG22485.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain Pkinase PF00069.25 OAG22486.1 - 1.1e-51 175.8 0.3 1.5e-27 96.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22486.1 - 1.3e-22 80.4 0.1 1.5e-14 53.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG22486.1 - 0.00022 20.2 0.0 0.00042 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG22486.1 - 0.0027 17.7 1.1 0.0053 16.7 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAG22486.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OAG22486.1 - 0.017 14.0 0.2 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Thiamine_BP PF01910.17 OAG22488.1 - 1.3e-31 108.3 0.0 1.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein SnoaL PF07366.12 OAG22490.1 - 2e-33 114.9 0.0 2.6e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG22490.1 - 5.6e-17 62.2 0.0 6.9e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.18 OAG22491.1 - 3.2e-06 27.1 7.9 5.7e-06 26.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG22491.1 - 3.3e-05 23.0 2.0 0.00053 19.1 2.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain L31 PF09784.9 OAG22492.1 - 5.9e-46 155.1 2.5 6.6e-46 154.9 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF4763 PF15960.5 OAG22492.1 - 0.072 12.4 0.4 0.083 12.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Lambda_tail_I PF06805.12 OAG22492.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Sedlin_N PF04628.13 OAG22493.1 - 7.6e-32 110.2 0.0 8.7e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rotamase PF00639.21 OAG22494.1 - 0.58 11.1 4.3 7.6 7.6 4.8 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain CPSase_L_D2 PF02786.17 OAG22496.1 - 1.3e-72 243.8 0.0 2.1e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG22496.1 - 2.8e-36 124.4 0.0 6.1e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG22496.1 - 2.4e-35 120.9 0.0 1e-34 118.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG22496.1 - 9.9e-16 57.3 0.7 2.6e-15 56.0 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG22496.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG22496.1 - 2.1e-09 37.2 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG22496.1 - 4.3e-06 26.5 0.0 0.00024 20.9 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 OAG22496.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 OAG22496.1 - 0.0098 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 OAG22496.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OAG22496.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RINGv PF12906.7 OAG22498.1 - 2.2e-16 59.7 9.2 4.2e-16 58.8 9.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAG22498.1 - 0.016 15.5 8.7 0.03 14.6 8.7 1.5 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 OAG22498.1 - 0.039 14.0 2.8 0.1 12.6 2.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2718 PF10918.8 OAG22498.1 - 0.095 13.2 1.3 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) SLC3A2_N PF16028.5 OAG22498.1 - 4 7.1 5.8 0.52 9.9 0.0 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus FANCL_C PF11793.8 OAG22498.1 - 7.1 6.9 7.1 11 6.3 5.0 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OAG22498.1 - 9.5 6.1 6.0 18 5.2 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_tran_WecB PF03808.13 OAG22499.1 - 0.36 10.8 10.9 3.4 7.6 0.1 5.1 4 2 0 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family Apolipoprotein PF01442.18 OAG22499.1 - 1.3 8.8 55.8 0.11 12.4 5.3 7.8 6 3 1 7 7 7 0 Apolipoprotein A1/A4/E domain FixS PF03597.15 OAG22500.1 - 2.5 7.9 3.7 4.3 7.1 3.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CAF-1_p150 PF11600.8 OAG22500.1 - 3.2 7.4 36.6 0.079 12.7 28.8 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.6 OAG22500.1 - 3.6 7.5 20.0 7.9 6.4 20.0 1.5 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.6 OAG22500.1 - 4.4 6.6 6.6 6.3 6.1 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Menin PF05053.13 OAG22500.1 - 6.8 4.9 8.9 8.1 4.7 8.9 1.2 1 0 0 1 1 1 0 Menin SAPS PF04499.15 OAG22500.1 - 7.4 5.2 7.1 12 4.6 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.16 OAG22502.1 - 4.7e-34 117.9 55.7 4.7e-34 117.9 55.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG22502.1 - 8.6e-05 21.5 27.5 0.00069 18.6 10.1 2.6 2 1 0 2 2 2 2 MFS_1 like family DUF1056 PF06341.11 OAG22502.1 - 1 9.7 5.6 9.6 6.6 1.0 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Peptidase_M14 PF00246.24 OAG22503.1 - 3.6e-82 276.4 0.1 5.1e-82 275.9 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OAG22503.1 - 4.1e-07 30.3 0.0 7.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_transf_20 PF00982.21 OAG22505.1 - 4.5e-202 671.9 0.0 5.1e-202 671.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 OAG22505.1 - 0.0012 19.3 0.0 0.0035 17.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAG22505.1 - 0.0045 16.7 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OAG22505.1 - 0.15 11.6 0.3 2.5 7.6 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Cellulase PF00150.18 OAG22508.1 - 5.2e-21 75.3 3.9 6.6e-21 75.0 3.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG22508.1 - 4.3e-05 22.8 0.1 0.00037 19.7 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 OAG22508.1 - 0.0032 16.8 0.2 0.012 14.9 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase SDF PF00375.18 OAG22510.1 - 4.2e-88 296.0 41.4 5.3e-88 295.7 41.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Kei1 PF08552.11 OAG22510.1 - 0.003 17.4 0.7 0.037 13.9 0.1 2.5 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 CAAD PF14159.6 OAG22510.1 - 0.2 11.5 5.9 0.067 13.0 1.2 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DJ-1_PfpI PF01965.24 OAG22511.1 - 6.7e-09 35.8 0.0 1.5e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG22511.1 - 1.1e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like FOP_dimer PF09398.10 OAG22511.1 - 0.025 14.8 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Zn_clus PF00172.18 OAG22512.1 - 1.1e-07 31.8 7.2 1.9e-07 31.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG22512.1 - 1e-05 24.6 2.2 1.5e-05 24.0 1.8 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAG22513.1 - 5.8e-30 104.5 0.0 6.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22513.1 - 6.6e-20 71.5 0.0 4.1e-19 68.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Glyco_transf_34 PF05637.12 OAG22514.1 - 5.1e-07 29.7 0.6 1.5e-06 28.1 0.6 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_79n PF03662.14 OAG22514.1 - 0.044 12.7 0.0 0.082 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Nucleotid_trans PF03407.16 OAG22514.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase HAD PF12710.7 OAG22515.1 - 0.0099 16.3 0.0 0.049 14.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MAPEG PF01124.18 OAG22516.1 - 1.7e-18 66.8 3.6 2.7e-18 66.1 3.6 1.3 1 1 0 1 1 1 1 MAPEG family Pesticin PF16754.5 OAG22516.1 - 0.051 13.5 0.1 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term ACPS PF01648.20 OAG22517.1 - 1.5e-07 31.6 0.1 1.3e-06 28.5 0.0 2.4 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 OAG22518.1 - 1.4e-52 178.3 0.0 4.2e-43 147.4 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG22518.1 - 1.1e-08 34.9 0.0 1.3e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 OAG22518.1 - 0.00032 20.5 0.1 0.0021 17.9 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 OAG22518.1 - 0.0034 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 OAG22518.1 - 0.0057 16.5 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF243 PF03103.17 OAG22518.1 - 0.12 12.7 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF243) RRM_1 PF00076.22 OAG22519.1 - 1.7e-16 59.8 0.0 2.4e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliD_C PF07195.12 OAG22520.1 - 0.28 10.5 4.1 0.077 12.4 0.3 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus dsDNA_bind PF01984.20 OAG22520.1 - 0.39 11.0 5.4 0.59 10.4 2.1 2.4 1 1 1 2 2 2 0 Double-stranded DNA-binding domain Methyltransf_11 PF08241.12 OAG22521.1 - 1.2e-20 74.0 0.1 3.6e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG22521.1 - 2.8e-17 62.9 0.0 4.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG22521.1 - 4.1e-17 62.7 0.0 8.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG22521.1 - 7.9e-13 48.3 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG22521.1 - 7.8e-12 45.0 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG22521.1 - 1.6e-10 41.1 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 OAG22521.1 - 3.3e-10 40.1 0.0 7.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_12 PF08242.12 OAG22521.1 - 8.6e-09 36.0 0.2 2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAG22521.1 - 0.0011 18.8 0.0 0.004 16.9 0.0 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OAG22521.1 - 0.015 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAG22521.1 - 0.018 14.0 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 OAG22521.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 OAG22521.1 - 0.028 13.9 0.0 0.068 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAG22521.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OAG22521.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 OAG22521.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_15 PF09445.10 OAG22521.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PfkB PF00294.24 OAG22522.1 - 4.7e-55 187.0 4.5 6e-55 186.7 4.5 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ApbE PF02424.15 OAG22522.1 - 0.015 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 ApbE family DUF829 PF05705.14 OAG22523.1 - 5e-47 160.8 0.0 1.4e-46 159.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF726 PF05277.12 OAG22524.1 - 1.1e-85 287.6 0.0 1.4e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 OAG22524.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 OAG22524.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF726 PF05277.12 OAG22525.1 - 1.3e-25 90.1 5.5 2.1e-25 89.4 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) polyprenyl_synt PF00348.17 OAG22526.1 - 1.3e-93 312.7 0.1 1.7e-93 312.3 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase AAA_15 PF13175.6 OAG22526.1 - 0.023 14.4 2.1 0.03 14.1 2.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain RNase_H2-Ydr279 PF09468.10 OAG22526.1 - 0.13 12.5 1.0 0.75 10.0 0.3 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ANAPC8 PF04049.13 OAG22527.1 - 8.3e-54 181.4 0.0 1.6e-53 180.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 OAG22527.1 - 1.6e-22 78.3 4.4 0.0011 18.7 0.5 7.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22527.1 - 8.1e-16 56.9 7.1 0.00083 19.4 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22527.1 - 1.9e-10 40.1 18.8 1.6 9.0 0.0 8.5 9 1 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22527.1 - 3.6e-10 39.8 17.0 0.037 14.8 0.0 8.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22527.1 - 6.7e-10 39.4 3.3 5.8e-05 23.7 0.3 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22527.1 - 4.9e-09 35.7 0.0 6e-06 25.8 0.0 4.3 4 1 1 5 5 5 1 TPR repeat ANAPC3 PF12895.7 OAG22527.1 - 4.1e-07 30.1 7.0 0.77 10.0 0.3 5.7 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAG22527.1 - 5.7e-06 26.8 6.1 0.23 12.0 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG22527.1 - 8.6e-06 25.8 1.0 3.3 8.3 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG22527.1 - 0.00026 21.0 0.9 5.9 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22527.1 - 0.0003 21.0 14.1 2.6 8.4 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG22527.1 - 0.0003 21.2 17.9 2.8 8.8 0.3 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG22527.1 - 0.004 16.4 1.0 0.004 16.4 1.0 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG22527.1 - 0.019 14.9 8.8 3 8.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG22527.1 - 0.035 14.2 0.3 38 4.5 0.1 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Mt_ATP-synt_B PF05405.14 OAG22527.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Arm-DNA-bind_3 PF13356.6 OAG22527.1 - 0.44 11.0 2.3 0.72 10.3 0.2 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain UPF0147 PF03685.13 OAG22529.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF3944 PF13099.6 OAG22530.1 - 0.0059 16.4 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3944) Omptin PF01278.20 OAG22531.1 - 0.021 13.9 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Omptin family ALGX PF16822.5 OAG22532.1 - 0.0011 18.7 0.8 0.002 17.8 0.8 1.3 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX Keratin_matx PF04579.12 OAG22532.1 - 0.19 12.1 4.8 1.1 9.6 0.2 2.7 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein DUF4710 PF15828.5 OAG22535.1 - 0.21 11.8 1.0 0.54 10.4 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DHHA2 PF02833.14 OAG22536.1 - 9.6e-41 139.3 1.0 1.6e-40 138.6 1.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OAG22536.1 - 7.6e-09 35.7 0.0 2.3e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 DHH family Abhydrolase_2 PF02230.16 OAG22537.1 - 8.7e-21 74.7 0.0 1.1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 OAG22537.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG22537.1 - 0.014 15.1 0.2 0.16 11.5 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG22537.1 - 0.015 14.6 0.0 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HTH_AsnC-type PF13404.6 OAG22537.1 - 0.054 13.3 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain FSH1 PF03959.13 OAG22537.1 - 0.18 11.5 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 OAG22537.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3759 PF12585.8 OAG22538.1 - 1.2e-39 134.3 6.8 1.5e-39 133.9 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 OAG22538.1 - 8.8 7.0 12.3 1.8 9.2 5.5 2.7 1 1 2 3 3 3 0 Domain of unknwon function (DUF3824) EXS PF03124.14 OAG22539.1 - 9e-49 166.6 3.4 1e-48 166.4 3.4 1.0 1 0 0 1 1 1 1 EXS family Nop14 PF04147.12 OAG22539.1 - 1.4 7.1 11.3 1.7 6.8 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAG22539.1 - 4.8 5.4 11.2 6.3 5.0 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.17 OAG22540.1 - 0.041 13.9 4.3 0.062 13.3 4.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF5396 PF17374.2 OAG22540.1 - 0.18 9.6 0.0 0.23 9.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5396) MFS_1 PF07690.16 OAG22541.1 - 2.3e-29 102.4 23.2 2.3e-29 102.4 23.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG22541.1 - 1.7e-12 47.0 0.1 1.7e-12 47.0 0.1 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 OAG22541.1 - 0.0077 14.5 3.7 0.015 13.5 3.7 1.4 1 0 0 1 1 1 1 BT1 family F-box-like PF12937.7 OAG22544.1 - 5.5e-06 26.2 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG22544.1 - 0.0063 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain TMEM119 PF15724.5 OAG22546.1 - 0.48 10.4 3.2 0.78 9.7 3.2 1.4 1 0 0 1 1 1 0 TMEM119 family Sugar_tr PF00083.24 OAG22548.1 - 1.4e-108 363.7 24.4 1.6e-108 363.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22548.1 - 2.5e-24 85.9 28.2 1.2e-16 60.7 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 OAG22548.1 - 2 8.5 9.4 0.57 10.2 2.5 2.7 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 OAG22548.1 - 3.8 7.3 9.3 8.7 6.2 2.4 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Egh16-like PF11327.8 OAG22549.1 - 2.7e-49 168.1 6.4 2.7e-49 168.1 6.4 2.2 2 1 0 2 2 2 1 Egh16-like virulence factor DUF4748 PF15932.5 OAG22550.1 - 1e-19 70.0 0.4 1.7e-19 69.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) MAP70 PF07058.11 OAG22550.1 - 0.13 10.9 0.2 0.14 10.9 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 NPCC PF08058.11 OAG22551.1 - 8.5e-33 113.2 0.0 1.1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex component Auxin_repressed PF05564.12 OAG22551.1 - 8.2 7.1 12.9 0.75 10.5 0.6 2.8 2 1 0 3 3 3 0 Dormancy/auxin associated protein AMP-binding PF00501.28 OAG22552.1 - 1.8e-18 66.4 0.1 1.3e-17 63.5 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme TNFR_16_TM PF18422.1 OAG22552.1 - 0.095 12.7 0.9 0.19 11.7 0.9 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Transp_cyt_pur PF02133.15 OAG22553.1 - 4.9e-100 335.4 46.6 5.6e-100 335.2 46.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adap_comp_sub PF00928.21 OAG22555.1 - 1.6e-91 306.4 0.0 2.1e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG22555.1 - 2.5e-09 37.2 0.2 4e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_UBOX PF13445.6 OAG22556.1 - 1.3e-07 31.5 1.5 3.3e-07 30.2 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG22556.1 - 3.3e-06 27.3 6.6 2.1e-05 24.8 6.6 2.3 1 1 0 1 1 1 1 Ring finger domain FYVE PF01363.21 OAG22556.1 - 1.2e-05 25.3 1.0 1.2e-05 25.3 1.0 2.1 2 1 0 2 2 2 1 FYVE zinc finger Prok-RING_4 PF14447.6 OAG22556.1 - 0.00011 21.9 4.4 0.0031 17.4 0.5 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG22556.1 - 0.00028 20.7 5.4 0.008 16.0 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG22556.1 - 0.00035 20.4 3.1 0.00086 19.1 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG22556.1 - 0.00046 20.4 4.5 0.0011 19.2 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG22556.1 - 0.0078 16.2 6.9 0.12 12.4 7.7 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-UDP PF14569.6 OAG22556.1 - 0.035 14.2 1.2 8 6.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 OAG22556.1 - 0.06 13.4 3.4 0.19 11.8 3.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OAG22556.1 - 0.08 12.6 3.8 0.24 11.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 OAG22556.1 - 0.11 12.4 0.7 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 OAG22556.1 - 0.3 10.9 6.2 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAG22556.1 - 0.59 10.4 10.3 0.24 11.6 6.3 2.4 2 1 1 3 3 3 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OAG22556.1 - 1.4 8.8 9.4 1.2 9.1 3.5 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG22556.1 - 3.6 7.8 8.1 0.24 11.6 0.3 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING PP2C PF00481.21 OAG22557.1 - 7.6e-31 107.7 0.1 1.1e-30 107.1 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAG22557.1 - 2.8e-07 30.4 0.5 0.0046 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 OAG22557.1 - 0.0034 17.3 0.3 0.74 9.7 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) COesterase PF00135.28 OAG22560.1 - 2.1e-93 313.9 0.2 5.4e-93 312.6 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG22560.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG22560.1 - 0.0012 18.3 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family RseA_C PF03873.13 OAG22561.1 - 0.018 15.3 0.3 0.018 15.3 0.3 1.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain NMO PF03060.15 OAG22562.1 - 4.3e-55 187.4 1.0 3.2e-53 181.3 1.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG22562.1 - 1.6e-12 47.1 0.1 5.8e-11 42.0 0.1 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG22562.1 - 0.00025 20.2 0.5 0.00047 19.3 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 OAG22562.1 - 0.0085 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) GMC_oxred_N PF00732.19 OAG22563.1 - 4.7e-61 206.8 0.0 5.9e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG22563.1 - 2.4e-29 102.7 0.0 4.2e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG22563.1 - 1.2e-06 27.8 0.0 3.8e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG22563.1 - 1.2e-05 24.7 0.0 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG22563.1 - 3.5e-05 23.5 2.2 9.8e-05 22.1 2.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG22563.1 - 0.0001 21.6 0.0 0.13 11.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG22563.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG22563.1 - 0.00028 20.2 0.1 0.00054 19.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG22563.1 - 0.0012 17.6 0.1 0.0047 15.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAG22563.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG22563.1 - 0.012 15.6 0.2 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG22563.1 - 0.02 14.1 0.1 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4646 PF15496.6 OAG22564.1 - 0.11 13.1 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Zn_clus PF00172.18 OAG22565.1 - 1.5e-07 31.4 14.1 2.4e-07 30.8 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3405 PF11885.8 OAG22566.1 - 1.5e-183 611.1 10.7 2e-183 610.8 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SEP PF08059.13 OAG22567.1 - 6.2e-27 94.0 0.0 1.3e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OAG22567.1 - 8.8e-15 54.7 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAG22567.1 - 5.1e-12 45.4 0.6 9.3e-12 44.6 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 OAG22567.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 TAP C-terminal domain TOM13 PF08219.11 OAG22568.1 - 2e-36 123.8 0.0 2.5e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 OAG22569.1 - 1.9e-17 63.6 0.2 2.6e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3275 PF11679.8 OAG22569.1 - 0.43 10.5 2.5 0.49 10.3 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) PLU-1 PF08429.11 OAG22570.1 - 1.5e-107 359.8 11.7 6.3e-106 354.4 11.6 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 OAG22570.1 - 7.3e-45 152.1 0.1 2.2e-44 150.5 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 OAG22570.1 - 6.8e-23 81.2 0.4 3.3e-22 79.0 0.1 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 OAG22570.1 - 7.2e-19 67.4 22.8 2e-10 40.4 4.7 3.1 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 OAG22570.1 - 9.2e-16 57.5 0.7 2.2e-15 56.3 0.7 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 OAG22570.1 - 1.1e-13 51.3 2.7 2.7e-13 50.1 2.7 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger Dynactin_p62 PF05502.13 OAG22570.1 - 0.043 12.6 1.0 0.11 11.3 1.0 1.6 1 0 0 1 1 1 0 Dynactin p62 family C1_1 PF00130.22 OAG22570.1 - 0.28 11.1 8.0 0.71 9.8 3.0 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 OAG22570.1 - 0.4 10.3 7.7 2.8 7.5 0.9 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Rubredoxin PF00301.20 OAG22570.1 - 3.4 7.8 7.1 3.9 7.6 0.3 3.5 4 0 0 4 4 3 0 Rubredoxin zf-HC5HC2H PF13771.6 OAG22570.1 - 4.1 7.7 15.0 0.13 12.6 2.1 3.4 3 0 0 3 3 3 0 PHD-like zinc-binding domain GIY-YIG PF01541.24 OAG22571.1 - 3.4e-20 72.1 0.0 1.1e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD PF00628.29 OAG22571.1 - 0.00092 19.1 4.1 0.0019 18.0 4.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 OAG22571.1 - 0.0037 17.6 5.7 0.0083 16.4 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAG22571.1 - 0.004 17.3 3.1 0.004 17.3 3.1 1.7 2 0 0 2 2 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OAG22571.1 - 0.0042 17.3 3.3 0.0087 16.3 3.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_2 PF03107.16 OAG22571.1 - 0.072 13.4 0.6 0.2 12.0 0.6 1.7 1 0 0 1 1 1 0 C1 domain T5orf172 PF10544.9 OAG22571.1 - 0.11 13.1 0.3 0.72 10.4 0.0 2.2 1 1 1 2 2 2 0 T5orf172 domain Zn_ribbon_17 PF17120.5 OAG22571.1 - 0.26 11.0 3.9 0.65 9.7 3.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OAG22571.1 - 0.45 10.9 5.0 1.7 9.0 5.0 2.1 1 1 0 1 1 1 0 RING-like domain DZR PF12773.7 OAG22571.1 - 0.45 10.6 4.6 7.4 6.7 4.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAG22571.1 - 0.5 10.5 2.9 13 6.0 0.7 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 OAG22571.1 - 0.52 10.3 4.6 5.7 7.0 2.9 2.3 2 0 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.6 OAG22571.1 - 0.79 9.7 7.4 0.72 9.8 4.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Thymidylate_kin PF02223.17 OAG22572.1 - 4e-44 150.5 0.0 5.5e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 OAG22572.1 - 0.02 15.4 0.0 0.031 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 OAG22572.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 OAG22572.1 - 0.097 12.1 0.0 0.32 10.4 0.0 2.0 1 1 0 1 1 1 0 Chromatin associated protein KTI12 GST_N_3 PF13417.6 OAG22575.1 - 8.4e-10 38.9 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG22575.1 - 3e-08 33.9 0.0 9.5e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG22575.1 - 8.5e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG22575.1 - 3.4e-05 24.1 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG22575.1 - 6.2e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG22575.1 - 0.00096 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.7 OAG22577.1 - 1.5e-18 68.3 0.1 1.9e-18 67.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG22577.1 - 2.5e-14 53.5 0.0 3.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG22577.1 - 1.1e-06 28.1 0.0 1.9e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 NUC205 PF08168.11 OAG22577.1 - 0.18 11.3 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 NUC205 domain p450 PF00067.22 OAG22578.1 - 4.6e-33 114.6 0.1 6.5e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 OAG22580.1 - 3.1e-46 157.9 0.1 4.5e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG22580.1 - 2.9e-09 36.7 8.3 2.9e-09 36.7 8.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Desulfoferrodox PF01880.18 OAG22580.1 - 0.061 13.9 0.0 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin Mito_carr PF00153.27 OAG22581.1 - 1.1e-11 44.5 1.4 0.0012 18.8 0.0 5.0 4 1 0 4 4 4 3 Mitochondrial carrier protein Herpes_DNAp_acc PF04929.12 OAG22581.1 - 0.075 12.0 1.3 0.17 10.9 1.3 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Fer2 PF00111.27 OAG22582.1 - 1.6e-14 53.6 0.9 1.6e-14 53.6 0.9 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 OAG22583.1 - 1.1e-37 129.3 11.2 1.1e-37 129.3 11.2 3.5 2 1 0 2 2 2 1 Rrp15p SRP54 PF00448.22 OAG22584.1 - 1.3e-75 253.4 1.4 3.5e-75 251.9 1.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAG22584.1 - 1.1e-31 109.3 4.7 1.1e-31 109.3 4.7 4.0 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 OAG22584.1 - 5.6e-21 74.6 1.0 1.4e-20 73.3 1.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 OAG22584.1 - 1.1e-06 28.8 0.2 3.8e-06 27.1 0.1 2.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 OAG22584.1 - 1.9e-06 27.6 0.3 6.6e-06 25.8 0.3 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 OAG22584.1 - 0.00069 20.0 0.0 0.0029 18.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG22584.1 - 0.0017 18.1 1.4 0.0033 17.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 OAG22584.1 - 0.0017 18.7 0.1 0.0044 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG22584.1 - 0.0021 18.5 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OAG22584.1 - 0.0022 17.3 0.0 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 OAG22584.1 - 0.0022 17.7 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase APS_kinase PF01583.20 OAG22584.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 OAG22584.1 - 0.0041 17.2 0.0 0.0091 16.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 OAG22584.1 - 0.012 15.6 0.1 0.035 14.0 0.1 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 OAG22584.1 - 0.013 15.3 0.7 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OAG22584.1 - 0.021 15.3 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OAG22584.1 - 0.047 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ResIII PF04851.15 OAG22584.1 - 0.05 13.6 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 OAG22584.1 - 0.051 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 OAG22584.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG22584.1 - 0.054 13.8 0.1 0.054 13.8 0.1 2.1 2 0 0 2 2 1 0 AAA domain SRPRB PF09439.10 OAG22584.1 - 0.059 12.8 1.1 5.8 6.3 0.1 3.3 3 1 0 4 4 4 0 Signal recognition particle receptor beta subunit DUF3052 PF11253.8 OAG22584.1 - 0.062 13.2 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3052) ApbA PF02558.16 OAG22584.1 - 0.063 12.9 1.2 5.5 6.6 0.2 2.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA MMR_HSR1 PF01926.23 OAG22584.1 - 0.069 13.2 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 OAG22584.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain FMO-like PF00743.19 OAG22586.1 - 1.1e-39 136.2 0.0 1.7e-22 79.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG22586.1 - 1.2e-12 47.6 0.6 2.1e-09 37.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG22586.1 - 1.7e-12 47.2 0.1 3.8e-08 33.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG22586.1 - 3e-12 46.4 0.0 1.2e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22586.1 - 1.9e-08 34.4 0.0 5.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG22586.1 - 2.2e-08 34.2 0.0 4.9e-07 29.9 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG22586.1 - 1.1e-05 24.9 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG22586.1 - 1.1e-05 25.3 0.1 0.019 14.6 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG22586.1 - 0.0048 15.6 0.0 0.04 12.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 OAG22586.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 OAG22586.1 - 0.048 14.2 0.0 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG22586.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NMT1 PF09084.11 OAG22587.1 - 1.6e-06 28.2 0.0 2.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 OAG22587.1 - 7.2e-05 22.3 0.0 0.00032 20.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAG22587.1 - 0.00026 20.7 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.6 OAG22587.1 - 0.0007 19.4 0.0 0.0018 18.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein NMT1_3 PF16868.5 OAG22587.1 - 0.0025 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family DUF3834 PF12916.7 OAG22587.1 - 0.051 12.8 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) NAPRTase_N PF17767.1 OAG22587.1 - 0.089 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Transferase PF02458.15 OAG22588.1 - 1.2e-20 73.6 0.0 1.5e-13 50.3 0.0 3.4 3 1 0 3 3 3 3 Transferase family MFS_1 PF07690.16 OAG22589.1 - 3.7e-26 91.9 78.2 2.3e-21 76.1 51.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily peroxidase PF00141.23 OAG22590.1 - 4.3e-21 75.7 0.3 6.9e-21 75.0 0.3 1.3 1 0 0 1 1 1 1 Peroxidase SET PF00856.28 OAG22591.1 - 1.6e-14 54.6 3.1 9.1e-14 52.2 0.6 2.6 2 1 0 2 2 2 1 SET domain Pes-10 PF07149.11 OAG22591.1 - 0.54 9.3 1.7 0.71 8.9 1.7 1.1 1 0 0 1 1 1 0 Pes-10 Esterase_phd PF10503.9 OAG22592.1 - 3.8e-21 75.6 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG22592.1 - 2.9e-08 33.4 0.1 4.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG22592.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_115 PF15979.5 OAG22593.1 - 3.6e-122 408.1 0.1 4.8e-122 407.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 OAG22593.1 - 9.7e-43 146.0 0.0 1.5e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain MFS_1 PF07690.16 OAG22594.1 - 1.6e-36 126.0 38.0 1.6e-36 126.0 38.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG22594.1 - 2.8e-13 49.5 1.3 2.8e-13 49.5 1.3 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Deltameth_res PF16020.5 OAG22594.1 - 0.53 10.2 2.6 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Deltamethrin resistance Zn_clus PF00172.18 OAG22595.1 - 2.5e-16 59.5 30.8 3.7e-09 36.6 10.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG22595.1 - 5.2e-13 48.6 1.3 6e-13 48.4 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.12 OAG22596.1 - 9.5e-19 68.1 0.0 1.7e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain YbjQ_1 PF01906.17 OAG22597.1 - 2.4e-23 82.7 0.5 3e-23 82.4 0.5 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Apo-CII PF05355.11 OAG22597.1 - 0.14 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein C-II Amidohydro_3 PF07969.11 OAG22598.1 - 7.8e-74 249.8 0.6 9.7e-74 249.5 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG22598.1 - 1.7e-15 57.2 0.3 2.9e-10 40.0 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family DIOX_N PF14226.6 OAG22599.1 - 6.6e-25 88.2 0.0 1.2e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG22599.1 - 3e-19 69.4 0.0 6.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cobW PF02492.19 OAG22600.1 - 6.8e-50 169.1 4.3 3.5e-36 124.4 0.5 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAG22600.1 - 4.7e-19 68.1 0.0 9.3e-15 54.3 0.0 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 OAG22600.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 OAG22600.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 OAG22600.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 OAG22600.1 - 0.022 15.2 0.0 0.079 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OAG22600.1 - 0.024 14.2 0.7 0.58 9.7 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 OAG22600.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OAG22600.1 - 0.038 13.3 0.2 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 OAG22600.1 - 0.056 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAG22600.1 - 0.057 12.4 0.6 2 7.3 0.1 2.8 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OAG22600.1 - 0.15 12.6 0.5 4.5 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Melibiase_2 PF16499.5 OAG22601.1 - 2.9e-52 177.6 9.0 4.5e-38 131.0 3.1 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 OAG22601.1 - 2.2e-10 40.4 0.1 6.8e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG22601.1 - 0.00038 19.5 0.1 0.00087 18.3 0.0 1.5 2 0 0 2 2 2 1 Melibiase Glyco_hyd_65N_2 PF14498.6 OAG22603.1 - 5.9e-46 157.2 0.2 1e-45 156.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain PHO4 PF01384.20 OAG22604.1 - 1.1e-118 396.2 18.9 1.3e-118 395.9 18.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family MCM PF00493.23 OAG22605.1 - 9.1e-105 348.7 0.1 2.1e-104 347.5 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OAG22605.1 - 3.8e-35 120.5 0.2 7.6e-35 119.5 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG22605.1 - 2.3e-29 101.7 1.5 5.7e-29 100.4 1.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG22605.1 - 1.1e-15 58.1 0.5 2.8e-15 56.8 0.5 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG22605.1 - 3.8e-06 26.5 0.0 0.00078 18.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG22605.1 - 2.2e-05 24.4 0.0 5.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG22605.1 - 0.00032 20.5 0.0 0.0013 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG22605.1 - 0.043 13.5 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAG22605.1 - 0.12 12.8 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hap4_Hap_bind PF10297.9 OAG22607.1 - 8.7e-07 28.9 5.4 8.7e-07 28.9 5.4 1.9 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 OAG22607.1 - 1.1e-05 25.4 15.3 2.2e-05 24.5 8.6 2.4 1 1 1 2 2 2 1 bZIP transcription factor DUF812 PF05667.11 OAG22607.1 - 0.00045 19.2 0.3 0.00061 18.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_2 PF07716.15 OAG22607.1 - 0.0013 18.8 17.1 0.053 13.6 7.0 2.6 2 0 0 2 2 2 2 Basic region leucine zipper CEP63 PF17045.5 OAG22607.1 - 0.1 12.5 8.2 0.15 11.9 8.2 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Noelin-1 PF12308.8 OAG22607.1 - 0.4 10.7 3.4 1.5 8.9 3.4 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein SIKE PF05769.11 OAG22607.1 - 0.47 10.4 7.7 0.78 9.6 7.7 1.3 1 0 0 1 1 1 0 SIKE family Fzo_mitofusin PF04799.13 OAG22607.1 - 1 8.9 4.5 1.7 8.2 4.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region UPF0242 PF06785.11 OAG22607.1 - 1.7 8.7 8.6 3.1 7.9 8.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS6_N PF14661.6 OAG22607.1 - 3.2 7.3 6.8 6.1 6.3 6.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Tho2 PF11262.8 OAG22607.1 - 6.8 5.8 6.6 11 5.1 6.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FmrO PF07091.11 OAG22609.1 - 0.1 12.1 0.8 0.15 11.6 0.8 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PhyH PF05721.13 OAG22610.1 - 1.6e-22 80.8 0.0 2.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_61 PF03443.14 OAG22611.1 - 1.3e-48 165.6 0.1 1.6e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 OAG22611.1 - 0.098 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Transglut_core PF01841.19 OAG22612.1 - 2.3e-12 47.4 0.1 6.5e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 OAG22612.1 - 1.8e-08 33.9 0.1 4.1e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG22612.1 - 1.9e-07 30.6 0.1 5.3e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG22612.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain CCDC32 PF14989.6 OAG22612.1 - 0.0027 17.7 0.8 0.0058 16.6 0.8 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing 32 tRNA-synt_1c PF00749.21 OAG22613.1 - 3.8e-104 348.0 0.0 5e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG22613.1 - 2.7e-34 118.5 0.1 5.8e-34 117.5 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GFA PF04828.14 OAG22615.1 - 3.1e-10 40.3 1.3 3.1e-10 40.3 1.3 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme IHABP4_N PF16174.5 OAG22615.1 - 1.9 9.0 11.6 0.37 11.4 3.5 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal zf-CHY PF05495.12 OAG22617.1 - 8.4e-14 51.8 14.0 2e-13 50.6 14.0 1.6 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 OAG22617.1 - 0.019 15.1 4.7 0.019 15.1 4.7 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 OAG22617.1 - 0.043 14.1 7.9 0.34 11.2 7.9 2.5 1 1 0 1 1 1 0 zinc-ribbon DpnI PF06044.12 OAG22617.1 - 0.26 10.9 3.7 0.12 12.0 1.4 1.5 1 1 1 2 2 2 0 Dam-replacing family HypA PF01155.19 OAG22617.1 - 0.48 10.5 9.4 3.1 7.8 9.4 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Evr1_Alr PF04777.13 OAG22617.1 - 0.71 10.4 9.3 4 8.0 5.3 2.6 1 1 1 2 2 2 0 Erv1 / Alr family Proteasome PF00227.26 OAG22618.1 - 3.3e-56 189.8 0.1 4.4e-56 189.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG22618.1 - 6.3e-13 48.1 0.3 2.1e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Tma16 PF11176.8 OAG22618.1 - 0.023 14.6 0.8 0.091 12.6 0.1 1.9 1 1 1 2 2 2 0 Translation machinery-associated protein 16 Terminase_5 PF06056.12 OAG22618.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) FAD-oxidase_C PF02913.19 OAG22619.1 - 4.3e-62 210.0 0.0 5.9e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG22619.1 - 2.2e-36 124.7 0.1 3.7e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amidohydro_2 PF04909.14 OAG22620.1 - 1.3e-33 117.1 0.0 2.6e-33 116.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase DBD_HTH PF18430.1 OAG22620.1 - 0.3 10.9 1.3 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Putative DNA-binding domain MTHFR PF02219.17 OAG22621.1 - 4.1e-100 334.8 0.0 8.4e-100 333.8 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF3449 PF11931.8 OAG22622.1 - 9.2e-78 260.3 0.6 9.2e-78 260.3 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAG22622.1 - 1.1e-25 89.9 1.6 1.1e-25 89.9 1.6 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 OAG22622.1 - 1.5e-09 37.9 2.2 1.1e-07 32.0 1.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG22622.1 - 3.5e-08 33.5 0.8 3.5e-08 33.5 0.8 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.8 OAG22622.1 - 3.2e-06 26.9 0.0 7.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 OAG22622.1 - 0.0093 16.3 1.0 0.059 13.7 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG22622.1 - 0.22 12.5 0.8 45 5.3 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PRP9_N PF16958.5 OAG22622.1 - 7.1 6.6 26.6 0.092 12.8 0.9 4.2 4 2 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus DEAD PF00270.29 OAG22623.1 - 2.1e-40 138.4 0.1 3.6e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG22623.1 - 2.1e-32 111.8 0.0 7.8e-32 109.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG22623.1 - 0.00041 20.1 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG22623.1 - 0.0014 19.0 0.5 0.018 15.4 0.5 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 OAG22623.1 - 0.0026 17.8 0.0 0.0058 16.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OAG22623.1 - 0.017 15.1 0.3 0.064 13.2 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain TniB PF05621.11 OAG22623.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 OAG22623.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 OAG22623.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Podoplanin PF05808.11 OAG22625.1 - 0.0011 19.1 0.2 0.002 18.2 0.2 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 OAG22625.1 - 0.0023 16.9 2.8 0.0034 16.3 2.8 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4381 PF14316.6 OAG22625.1 - 0.0059 16.9 0.6 1.4 9.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 OAG22625.1 - 0.0059 15.4 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E LapA_dom PF06305.11 OAG22625.1 - 0.11 12.3 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Bacteriocin_IIc PF10439.9 OAG22625.1 - 5.7 7.1 8.9 15 5.8 8.9 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DDR PF08841.10 OAG22626.1 - 0.0027 16.7 1.0 0.009 15.0 0.5 1.8 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF460 PF04312.13 OAG22626.1 - 0.045 13.5 0.1 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF460) MreB_Mbl PF06723.13 OAG22626.1 - 0.05 12.4 0.1 0.28 10.0 0.1 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Mad3_BUB1_I_2 PF17014.5 OAG22626.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein HSP70 PF00012.20 OAG22626.1 - 0.26 9.4 0.1 1.1 7.3 0.1 1.9 2 0 0 2 2 2 0 Hsp70 protein TBK1_CCD1 PF18394.1 OAG22628.1 - 0.029 14.0 1.2 0.032 13.8 1.2 1.1 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 DUF1919 PF08942.10 OAG22628.1 - 0.084 12.3 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) Prefoldin PF02996.17 OAG22629.1 - 0.015 15.2 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 OAG22629.1 - 0.088 13.4 0.7 17 6.0 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal F-box PF00646.33 OAG22630.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 F-box domain HTH_50 PF18024.1 OAG22630.1 - 0.059 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Fungal_trans_2 PF11951.8 OAG22631.1 - 7.6e-08 31.6 0.0 9.5e-08 31.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haemadin PF09065.10 OAG22632.1 - 0.18 11.7 1.1 0.5 10.2 1.1 1.8 1 0 0 1 1 1 0 Haemadin Vps39_1 PF10366.9 OAG22633.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Na_H_Exchanger PF00999.21 OAG22635.1 - 5.6e-26 91.2 43.0 1.2e-19 70.4 25.8 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family MdcE PF06833.11 OAG22635.1 - 1.5 8.2 3.9 3.5 7.1 0.2 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Glyco_hydro_10 PF00331.20 OAG22637.1 - 4.1e-100 335.0 0.3 4.7e-100 334.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Anoctamin PF04547.12 OAG22638.1 - 5.8e-106 355.0 3.3 6.9e-106 354.8 3.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ANAPC3 PF12895.7 OAG22639.1 - 5.8e-30 103.4 5.8 7.1e-24 83.8 0.2 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAG22639.1 - 2.1e-28 97.0 0.0 4.7e-06 26.2 0.1 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22639.1 - 1.5e-25 87.2 10.6 0.00014 21.7 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG22639.1 - 3.5e-22 78.7 5.0 4.4e-06 27.1 0.0 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22639.1 - 3.6e-21 73.6 0.5 0.0005 20.1 0.1 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22639.1 - 1.6e-15 57.2 15.0 4.8e-07 30.0 0.1 8.0 7 4 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22639.1 - 2.3e-13 49.8 11.1 0.14 13.0 0.1 8.4 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22639.1 - 9e-13 48.6 8.2 0.27 11.9 0.0 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22639.1 - 1.5e-11 43.7 2.8 0.43 10.3 0.0 7.5 8 1 1 9 9 9 3 TPR repeat TPR_7 PF13176.6 OAG22639.1 - 3e-07 30.0 11.5 0.88 9.7 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG22639.1 - 2e-06 27.8 0.8 30 5.3 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG22639.1 - 7.7e-06 25.6 2.6 1.4 8.9 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG22639.1 - 1.7e-05 25.1 8.3 1.4 9.7 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAG22639.1 - 2.8e-05 23.5 0.2 0.76 8.9 0.1 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG22639.1 - 4e-05 23.2 1.3 0.03 13.7 0.0 4.0 4 1 1 5 5 5 1 MalT-like TPR region TPR_9 PF13371.6 OAG22639.1 - 0.00034 20.7 9.7 1.4 9.1 0.2 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat PPR PF01535.20 OAG22639.1 - 0.00091 19.3 0.4 18 5.9 0.0 5.0 4 0 0 4 4 4 0 PPR repeat TPR_5 PF12688.7 OAG22639.1 - 0.0029 17.8 0.3 0.02 15.1 0.0 2.6 4 0 0 4 4 1 1 Tetratrico peptide repeat TPR_4 PF07721.14 OAG22639.1 - 0.0032 17.9 5.8 25 5.9 0.0 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat ATP11 PF06644.11 OAG22639.1 - 0.0053 16.6 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 ATP11 protein FAT PF02259.23 OAG22639.1 - 0.054 12.7 0.2 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 FAT domain Fis1_TPR_C PF14853.6 OAG22639.1 - 0.055 13.6 7.1 4.2 7.5 0.1 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 OAG22639.1 - 0.068 12.6 0.4 4.1 6.7 0.0 3.3 3 1 1 4 4 4 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 OAG22639.1 - 0.088 12.8 0.0 9.9 6.2 0.0 3.6 2 1 0 2 2 2 0 Putative TPR-like repeat TEX29 PF15839.5 OAG22639.1 - 0.53 10.9 2.3 28 5.4 2.3 2.3 1 1 0 1 1 1 0 Testis-expressed sequence 29 protein RPN7 PF10602.9 OAG22639.1 - 1.2 8.8 6.5 18 5.0 0.0 4.3 4 1 1 5 5 5 0 26S proteasome subunit RPN7 DUF572 PF04502.13 OAG22640.1 - 3.8e-73 247.0 17.5 4.7e-73 246.7 16.9 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 OAG22640.1 - 0.046 13.8 2.4 0.22 11.6 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Glyco_hydro_32N PF00251.20 OAG22641.1 - 0.0026 17.4 0.1 0.0062 16.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 OAG22641.1 - 0.0032 16.8 2.6 0.0077 15.6 2.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 CENP-B_dimeris PF09026.10 OAG22643.1 - 0.03 14.7 6.6 0.06 13.7 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAG22643.1 - 4.4 6.5 7.7 6.4 6.0 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAG22643.1 - 7 4.6 5.2 9.6 4.2 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3237 PF11578.8 OAG22646.1 - 5e-19 68.6 0.1 5.6e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.12 OAG22648.1 - 3.1e-33 113.9 0.5 6.8e-33 112.8 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG22648.1 - 8.6e-17 61.3 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG22648.1 - 3.1e-09 36.6 0.0 5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG22648.1 - 1.8e-05 25.8 0.0 2.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.19 OAG22648.1 - 0.019 14.7 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Staph_opine_DH PF10100.9 OAG22648.1 - 0.089 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG22648.1 - 0.095 13.0 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 OAG22648.1 - 0.33 10.3 1.8 0.25 10.7 0.2 1.5 2 0 0 2 2 2 0 ThiF family NAD_binding_10 PF13460.6 OAG22649.1 - 3e-15 56.6 0.1 5.4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG22649.1 - 5.2e-12 45.8 0.0 7.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 OAG22649.1 - 0.00023 21.6 0.1 0.00049 20.5 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG22649.1 - 0.00033 20.2 0.1 0.00055 19.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG22649.1 - 0.0032 17.6 0.1 0.0053 16.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAG22649.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 OAG22649.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG22649.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 OAG22649.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AT_hook PF02178.19 OAG22650.1 - 0.24 11.4 4.6 0.43 10.6 4.6 1.4 1 0 0 1 1 1 0 AT hook motif EMP24_GP25L PF01105.24 OAG22651.1 - 7.1e-46 156.4 1.6 8.2e-46 156.2 1.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Macoilin PF09726.9 OAG22651.1 - 0.04 12.5 0.1 0.049 12.2 0.1 1.1 1 0 0 1 1 1 0 Macoilin family USP7_ICP0_bdg PF12436.8 OAG22652.1 - 2.5e-79 266.0 0.6 1.5e-78 263.4 0.1 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAG22652.1 - 1.3e-69 234.1 1.3 8.4e-69 231.4 0.3 2.5 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAG22652.1 - 3.7e-47 161.0 0.5 1.2e-46 159.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG22652.1 - 1.1e-20 74.5 0.0 3.9e-20 72.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAG22652.1 - 6.4e-08 32.8 0.0 2.2e-07 31.0 0.0 2.0 1 1 1 2 2 2 1 MATH domain HTH_Tnp_1 PF01527.20 OAG22652.1 - 0.011 16.1 0.0 0.035 14.4 0.0 1.9 1 0 0 1 1 1 0 Transposase BCDHK_Adom3 PF10436.9 OAG22653.1 - 1e-44 152.2 0.1 1.6e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG22653.1 - 6.9e-06 26.5 0.0 4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG22653.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Adeno_E1B_55K PF01696.17 OAG22654.1 - 0.017 13.8 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Oxidored_molyb PF00174.19 OAG22655.1 - 7.5e-62 208.0 0.0 1.2e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG22655.1 - 8.2e-25 87.4 0.5 1.7e-24 86.4 0.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 OAG22655.1 - 0.11 13.2 0.9 0.34 11.7 0.0 2.2 3 0 0 3 3 3 0 Bacterial Ig domain UQ_con PF00179.26 OAG22656.1 - 4.9e-53 178.5 0.1 5.5e-53 178.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG22656.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B FAD_binding_8 PF08022.12 OAG22657.1 - 3.6e-19 68.9 0.0 7.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG22657.1 - 1.2e-17 64.4 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG22657.1 - 6.9e-11 42.4 9.2 6.9e-11 42.4 9.2 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 OAG22657.1 - 0.0048 17.3 1.0 0.014 15.8 1.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_6 PF00970.24 OAG22657.1 - 0.054 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Abhydrolase_3 PF07859.13 OAG22658.1 - 5.2e-26 91.8 0.0 7e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG22658.1 - 0.00034 19.6 0.0 0.00044 19.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase CRM1_repeat_3 PF18787.1 OAG22658.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 Glyco_hydro_43 PF04616.14 OAG22660.1 - 1.6e-32 113.0 6.3 2.4e-32 112.4 6.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 OAG22661.1 - 2e-74 251.0 0.0 2.3e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5101 PF17031.5 OAG22661.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Glyco_hydro_92 PF07971.12 OAG22662.1 - 1.9e-143 478.7 0.0 2.3e-143 478.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG22662.1 - 1.6e-67 227.9 1.5 2.4e-67 227.3 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain E1-E2_ATPase PF00122.20 OAG22663.1 - 2.8e-37 128.0 17.8 6.1e-31 107.3 0.0 4.0 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG22663.1 - 3.7e-27 95.2 1.5 3.7e-27 95.2 1.5 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG22663.1 - 2.6e-19 70.3 1.2 2.7e-16 60.5 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG22663.1 - 9.8e-17 60.4 0.0 3.1e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG22663.1 - 2.5e-10 40.3 0.0 5.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG22663.1 - 2.8e-06 27.2 1.2 7.8e-06 25.8 0.8 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1385 PF07136.11 OAG22663.1 - 0.33 10.2 2.8 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Rap_GAP PF02145.15 OAG22664.1 - 0.095 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Rap/ran-GAP zf-RING_2 PF13639.6 OAG22667.1 - 5.4e-07 29.8 7.0 7.7e-07 29.3 7.0 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAG22667.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG22667.1 - 0.00023 21.0 5.7 0.00035 20.4 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG22667.1 - 0.00096 19.1 3.4 0.00096 19.1 3.4 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG22667.1 - 0.0057 16.7 0.8 0.0087 16.1 0.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG22667.1 - 0.006 16.4 7.5 0.009 15.9 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG22667.1 - 0.035 14.4 4.2 0.058 13.7 4.2 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG22667.1 - 0.035 13.9 5.2 0.093 12.5 5.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OAG22667.1 - 0.062 13.3 6.0 0.18 11.8 6.1 1.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG22667.1 - 2.7 7.9 9.1 11 5.9 9.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OAG22667.1 - 8.6 6.1 6.0 1.6 8.4 0.9 2.0 2 0 0 2 2 2 0 P-11 zinc finger HDA2-3 PF11496.8 OAG22668.1 - 2.3e-07 30.3 0.6 0.0049 16.1 0.1 2.7 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 OAG22668.1 - 0.0002 21.2 1.1 0.00049 19.9 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Csm1_N PF18504.1 OAG22668.1 - 0.019 15.3 1.8 0.019 15.3 1.8 6.0 4 2 1 6 6 6 0 Csm1 N-terminal domain Spectrin PF00435.21 OAG22668.1 - 1.8 9.1 31.2 1.6 9.2 7.3 4.9 4 0 0 4 4 4 0 Spectrin repeat NPV_P10 PF05531.12 OAG22668.1 - 3.5 8.2 10.4 7.1 7.2 0.6 4.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Mobilization_B PF17511.2 OAG22668.1 - 7.1 7.0 8.0 6.1 7.2 5.5 2.3 1 1 0 1 1 1 0 Mobilization protein B Imm25 PF15564.6 OAG22669.1 - 0.0069 16.3 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 25 CDC45 PF02724.14 OAG22669.1 - 2.9 6.1 5.2 4.6 5.4 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein UPF0029 PF01205.19 OAG22670.1 - 3.9e-37 126.8 0.0 6.3e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAG22670.1 - 8.1e-07 29.3 0.0 3.6e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 OAG22670.1 - 0.027 14.1 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.6 OAG22671.1 - 1.8e-07 31.4 7.1 2.9e-07 30.7 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG22671.1 - 2.9e-05 24.0 3.8 5.7e-05 23.0 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG22671.1 - 0.00015 21.6 5.3 0.00026 20.8 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG22671.1 - 0.00063 19.6 6.3 0.055 13.3 6.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG22671.1 - 0.0014 18.9 5.4 0.0026 18.0 5.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG22671.1 - 0.0021 17.9 7.3 0.0034 17.2 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG22671.1 - 0.0042 17.0 6.6 0.014 15.3 6.6 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAG22671.1 - 0.056 13.3 4.5 0.12 12.2 4.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG22671.1 - 0.11 12.7 5.4 0.72 10.1 5.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG22671.1 - 0.13 12.2 8.5 0.31 10.9 8.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tropomodulin PF03250.14 OAG22671.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Tropomodulin zf-RING_11 PF17123.5 OAG22671.1 - 1.1 9.1 5.0 2.2 8.1 4.9 1.6 1 1 0 1 1 1 0 RING-like zinc finger adh_short_C2 PF13561.6 OAG22673.1 - 4.3e-61 206.5 0.2 4.9e-61 206.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG22673.1 - 3.2e-43 147.5 0.5 3.8e-43 147.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG22673.1 - 1e-15 58.1 0.3 1.5e-15 57.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.10 OAG22673.1 - 0.054 12.4 0.1 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Acyl-CoA_dh_1 PF00441.24 OAG22674.1 - 7.8e-30 104.1 0.2 1.1e-29 103.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG22674.1 - 7.1e-25 87.0 0.1 1.2e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG22674.1 - 1.2e-20 74.2 0.1 3.1e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG22674.1 - 0.0072 16.6 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 OAG22674.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal BSMAP PF12280.8 OAG22678.1 - 0.0082 16.4 0.5 0.022 15.0 0.5 1.7 1 0 0 1 1 1 1 Brain specific membrane anchored protein AP3D1 PF06375.11 OAG22678.1 - 1.4 9.2 11.4 0.74 10.0 4.6 3.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF3408 PF11888.8 OAG22678.1 - 6.5 6.9 7.6 1.7 8.8 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CoaE PF01121.20 OAG22679.1 - 2.9e-42 144.4 0.0 4.6e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 OAG22679.1 - 0.0015 18.7 0.0 0.011 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG22679.1 - 0.024 15.2 0.1 0.14 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain CAF1C_H4-bd PF12265.8 OAG22680.1 - 9.3e-26 89.9 0.8 2.2e-24 85.5 0.3 3.0 2 1 1 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG22680.1 - 3.5e-18 65.6 6.6 0.00061 20.6 0.4 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SPC22 PF04573.12 OAG22682.1 - 7.8e-40 136.1 0.5 4.3e-38 130.5 0.5 2.1 1 1 0 1 1 1 1 Signal peptidase subunit ParA PF10609.9 OAG22683.1 - 1.1e-87 293.6 0.0 2.2e-59 200.9 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG22683.1 - 7.8e-13 48.6 0.0 6.6e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 OAG22683.1 - 1.7e-06 27.5 0.0 6.5e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 OAG22683.1 - 1.1e-05 24.9 0.3 6e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 OAG22683.1 - 5.3e-05 23.2 0.3 0.00031 20.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OAG22683.1 - 0.0019 18.0 1.4 0.21 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAG22683.1 - 0.0022 17.0 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OAG22683.1 - 0.0048 16.5 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 OAG22683.1 - 0.025 14.0 0.1 0.075 12.5 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 OAG22683.1 - 0.032 13.5 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 OAG22683.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP-synt_J PF04911.12 OAG22683.1 - 0.096 12.3 0.8 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 ATP synthase j chain CLP1_P PF16575.5 OAG22683.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 OAG22683.1 - 0.25 11.2 1.9 0.35 10.8 0.8 1.7 2 0 0 2 2 2 0 RsgA GTPase DHR10 PF18595.1 OAG22684.1 - 0.21 11.7 6.4 0.52 10.4 6.4 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DivIC PF04977.15 OAG22684.1 - 1.2 9.0 4.4 3.1 7.6 4.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Aldo_ket_red PF00248.21 OAG22686.1 - 2.4e-54 184.6 0.0 2.7e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ad_Cy_reg PF16701.5 OAG22686.1 - 0.2 11.4 0.0 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain LCCL PF03815.19 OAG22687.1 - 5e-21 74.6 0.0 8.3e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.21 OAG22688.1 - 1.3e-09 37.8 0.0 5.4e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II GMC_oxred_C PF05199.13 OAG22689.1 - 9.7e-28 97.5 0.0 1.8e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG22689.1 - 1.4e-23 83.7 0.1 5.6e-18 65.3 0.1 3.1 2 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG22689.1 - 2.4e-06 27.0 0.0 2.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22689.1 - 5.8e-05 23.2 0.1 0.00018 21.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG22689.1 - 6.9e-05 22.6 0.0 0.0013 18.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG22689.1 - 0.00044 19.4 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG22689.1 - 0.0014 17.7 0.1 0.0063 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG22689.1 - 0.0076 15.5 0.0 3.8 6.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG22689.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CFEM PF05730.11 OAG22690.1 - 1.1e-10 41.4 12.0 1.9e-10 40.7 12.0 1.3 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.17 OAG22691.1 - 6.3e-47 160.5 0.0 8.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF3237 PF11578.8 OAG22693.1 - 1.6e-24 86.4 0.1 7.6e-23 81.0 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DUF1115 PF06544.12 OAG22693.1 - 3.9e-12 46.5 0.0 6.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DDHD PF02862.17 OAG22695.1 - 2.7e-60 204.3 6.7 1.7e-59 201.7 0.0 2.7 2 1 0 2 2 2 1 DDHD domain RNase_3_N PF18497.1 OAG22695.1 - 0.029 14.6 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain WWE PF02825.20 OAG22695.1 - 0.082 13.5 0.0 0.29 11.8 0.0 1.9 1 0 0 1 1 1 0 WWE domain OAD_gamma PF04277.13 OAG22695.1 - 0.098 13.3 1.5 17 6.1 0.2 3.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain XS PF03468.14 OAG22696.1 - 0.097 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 XS domain MR_MLE_C PF13378.6 OAG22698.1 - 2.7e-58 197.1 0.0 3.5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG22698.1 - 1.7e-16 60.5 0.0 3.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 OAG22699.1 - 3.6e-26 91.5 0.0 6.1e-26 90.8 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 OAG22700.1 - 9.3e-19 67.6 57.0 9.3e-18 64.3 51.0 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily LtrA PF06772.11 OAG22701.1 - 2.1e-20 73.3 22.5 3.9e-20 72.4 16.3 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Glyco_hydro_43 PF04616.14 OAG22702.1 - 1.3e-29 103.4 7.8 1.3e-29 103.4 7.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG22702.1 - 6.6e-26 91.3 0.8 1e-25 90.7 0.8 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Aminotran_5 PF00266.19 OAG22704.1 - 2.7e-58 197.7 0.0 5.8e-58 196.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG22704.1 - 2.6e-06 26.3 0.0 7.4e-06 24.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DAP3 PF10236.9 OAG22704.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2985 PF11204.8 OAG22704.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) COG2 PF06148.11 OAG22706.1 - 0.0005 20.2 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 F-box-like PF12937.7 OAG22707.1 - 6.6e-08 32.3 1.2 1.2e-06 28.3 1.2 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 OAG22707.1 - 0.19 11.7 1.4 0.65 9.9 0.1 2.5 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 OAG22708.1 - 9.8e-20 70.8 37.6 3.7e-17 62.3 34.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG22708.1 - 0.00091 18.2 30.9 2 7.2 24.2 3.7 1 1 2 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 OAG22708.1 - 0.52 10.0 8.4 1.4 8.6 0.1 2.7 2 1 0 3 3 3 0 Haemolysin-III related DUF4231 PF14015.6 OAG22708.1 - 1.7 9.1 4.3 0.99 9.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) FMO-like PF00743.19 OAG22710.1 - 8.3e-18 64.1 0.3 2.6e-17 62.5 0.1 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG22710.1 - 1.2e-05 25.5 0.0 0.00018 21.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG22710.1 - 4.2e-05 22.9 0.0 0.00041 19.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG22710.1 - 8.8e-05 21.9 0.1 0.00034 20.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG22710.1 - 0.0016 17.8 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG22710.1 - 0.11 12.5 0.1 3.1 7.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG22710.1 - 0.15 12.0 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Malic_M PF03949.15 OAG22710.1 - 0.16 11.2 0.2 0.47 9.7 0.1 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain CNH PF00780.22 OAG22711.1 - 4.5e-77 259.4 0.0 6.6e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAG22711.1 - 6e-31 108.1 0.0 9.7e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 OAG22711.1 - 4.9e-13 49.3 0.0 1e-11 45.1 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAG22711.1 - 0.012 16.1 0.0 0.13 12.8 0.0 2.5 3 0 0 3 3 3 0 PH domain SARAF PF06682.12 OAG22712.1 - 0.04 13.6 0.2 0.097 12.3 0.0 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CFEM PF05730.11 OAG22712.1 - 0.066 13.3 3.9 0.15 12.2 3.9 1.5 1 1 0 1 1 1 0 CFEM domain Gram_pos_anchor PF00746.21 OAG22712.1 - 0.2 11.6 3.6 0.27 11.2 2.3 1.9 1 1 1 2 2 2 0 LPXTG cell wall anchor motif DUF2637 PF10935.8 OAG22713.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) LapA_dom PF06305.11 OAG22713.1 - 0.12 12.2 0.6 0.18 11.7 0.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PNRC PF15365.6 OAG22714.1 - 0.019 14.8 1.6 0.019 14.8 1.6 2.2 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif AA_permease PF00324.21 OAG22715.1 - 2.2e-123 412.4 36.6 2.6e-123 412.2 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG22715.1 - 6.6e-36 124.1 38.5 8.2e-36 123.7 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease Prion_bPrPp PF11587.8 OAG22715.1 - 0.75 9.7 3.1 1.5 8.7 0.1 2.8 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal MFS_1 PF07690.16 OAG22716.1 - 3.6e-40 138.0 36.5 1.4e-39 136.1 35.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 OAG22716.1 - 0.19 10.7 31.9 0.59 9.1 10.9 2.2 2 0 0 2 2 2 0 Acyltransferase family LapA_dom PF06305.11 OAG22716.1 - 1 9.2 7.3 11 6.0 0.4 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain OATP PF03137.20 OAG22716.1 - 2.2 6.4 10.2 0.043 12.1 2.3 2.0 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2052 PF09747.9 OAG22717.1 - 2.4e-24 86.6 22.9 5.7e-13 49.4 2.1 3.0 2 1 1 3 3 3 2 Coiled-coil domain containing protein (DUF2052) MCM6_C PF18263.1 OAG22717.1 - 0.52 10.6 2.9 2.7 8.3 0.1 2.8 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Spermine_synth PF01564.17 OAG22718.1 - 1.1e-06 28.2 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 OAG22718.1 - 0.094 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 OAG22719.1 - 6e-49 166.8 0.0 8.1e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22719.1 - 1.4e-28 99.9 0.1 2.2e-26 92.7 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG22719.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG22719.1 - 0.067 12.0 0.0 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase HET PF06985.11 OAG22721.1 - 3.4e-22 79.4 0.1 9.5e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Amino_oxidase PF01593.24 OAG22722.1 - 1.9e-22 80.2 0.0 1.1e-21 77.7 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG22722.1 - 1e-10 41.6 0.1 2.8e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG22722.1 - 2.7e-07 30.5 0.0 1.5e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG22722.1 - 1.9e-05 24.0 0.0 3.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG22722.1 - 0.0052 16.1 0.1 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG22722.1 - 0.023 13.4 0.1 0.87 8.2 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 OAG22722.1 - 0.091 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 OAG22722.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RRM_1 PF00076.22 OAG22723.1 - 1.9e-11 43.6 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG22723.1 - 0.00061 19.7 0.0 0.00087 19.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_4 PF01565.23 OAG22724.1 - 2.2e-24 85.8 0.2 7.1e-24 84.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG22724.1 - 0.14 12.3 0.9 0.47 10.6 0.0 2.4 3 0 0 3 3 3 0 Berberine and berberine like DHHA1 PF02272.19 OAG22724.1 - 0.18 12.2 0.1 0.46 10.9 0.1 1.6 1 0 0 1 1 1 0 DHHA1 domain DUF2561 PF10812.8 OAG22725.1 - 0.046 13.7 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) zf-CCCH_2 PF14608.6 OAG22726.1 - 1.7e-08 34.6 52.7 0.0087 16.5 5.3 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger CFEM PF05730.11 OAG22728.1 - 0.012 15.7 18.9 0.024 14.7 5.5 2.6 2 1 0 2 2 2 0 CFEM domain CFEM PF05730.11 OAG22729.1 - 0.067 13.3 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 CFEM domain DAP10 PF07213.11 OAG22729.1 - 0.09 12.7 0.8 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 DAP10 membrane protein SKG6 PF08693.10 OAG22729.1 - 0.17 11.3 1.1 0.35 10.3 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG22729.1 - 0.71 10.0 11.1 0.21 11.7 7.1 2.1 2 1 0 2 2 2 0 Podoplanin LAX PF15681.5 OAG22730.1 - 0.0036 16.2 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Lymphocyte activation family X Fungal_trans PF04082.18 OAG22731.1 - 1.3e-10 40.8 0.3 2.1e-10 40.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22731.1 - 9.3e-08 32.1 8.9 2e-07 31.0 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG22732.1 - 1.6e-34 119.1 0.1 2.9e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22732.1 - 4.1e-23 82.2 0.0 1.1e-14 54.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22732.1 - 3.3e-10 40.2 0.0 5.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG22732.1 - 0.00044 19.8 0.0 0.00085 18.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG22732.1 - 0.011 15.6 0.0 0.044 13.7 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG22732.1 - 0.16 11.4 0.1 0.3 10.5 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase HET PF06985.11 OAG22734.1 - 2.1e-11 44.4 3.6 4.5e-08 33.6 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.14 OAG22735.1 - 1.2e-105 354.0 8.8 1.4e-105 353.8 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UPF0261 PF06792.11 OAG22736.1 - 2.7e-173 576.6 2.3 3.1e-173 576.4 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Peptidase_S28 PF05577.12 OAG22736.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PEP_hydrolase PF09370.10 OAG22737.1 - 1.2e-136 454.2 0.8 1.3e-136 454.0 0.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 OAG22737.1 - 0.00014 21.4 0.1 0.00021 20.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase S-methyl_trans PF02574.16 OAG22737.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase MFS_1 PF07690.16 OAG22738.1 - 4.7e-39 134.3 29.7 6.5e-39 133.9 29.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HAS-barrel PF09378.10 OAG22738.1 - 0.018 15.2 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 HAS barrel domain Oxidored_q2 PF00420.24 OAG22738.1 - 0.025 14.2 0.5 0.025 14.2 0.5 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Fungal_trans PF04082.18 OAG22739.1 - 4.6e-14 52.1 0.4 8.3e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22739.1 - 2.1e-07 31.0 10.4 3.8e-07 30.1 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 OAG22740.1 - 1.3e-61 208.0 0.0 1.7e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SurA_N_3 PF13624.6 OAG22741.1 - 0.029 14.2 3.5 0.06 13.1 3.5 1.6 1 0 0 1 1 1 0 SurA N-terminal domain SurA_N_2 PF13623.6 OAG22741.1 - 0.26 11.1 3.6 0.5 10.2 3.6 1.4 1 0 0 1 1 1 0 SurA N-terminal domain Gly_transf_sug PF04488.15 OAG22743.1 - 5.1e-13 49.5 0.3 1.2e-12 48.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OAG22743.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.5 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.22 OAG22744.1 - 3.6e-33 115.0 29.7 5.1e-33 114.5 29.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.8 OAG22745.1 - 0.00076 18.9 0.2 0.0017 17.7 0.2 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG22745.1 - 0.0016 18.1 0.2 0.0032 17.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Hydantoinase_B PF02538.14 OAG22746.1 - 3.6e-217 721.9 0.1 5.5e-217 721.3 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG22746.1 - 7.7e-102 340.5 0.2 1.3e-101 339.7 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG22746.1 - 3.2e-59 199.6 1.4 7.4e-58 195.2 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region O-antigen_lig PF13425.6 OAG22747.1 - 0.011 14.5 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BST2 PF16716.5 OAG22747.1 - 0.37 11.4 5.2 0.26 11.9 0.5 2.9 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 FMO-like PF00743.19 OAG22749.1 - 5.1e-16 58.2 0.0 2e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG22749.1 - 1e-11 44.6 0.0 8.2e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG22749.1 - 2.2e-09 36.9 0.0 8.3e-07 28.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG22749.1 - 1.9e-08 34.0 0.0 1.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22749.1 - 4.7e-08 33.2 0.0 1.1e-05 25.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG22749.1 - 8.5e-06 26.3 0.2 0.0078 16.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG22749.1 - 0.012 16.0 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 OAG22749.1 - 0.033 13.7 0.4 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OAG22749.1 - 0.04 13.3 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAG22749.1 - 0.063 13.3 0.1 6.1 6.8 0.1 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG22749.1 - 0.093 12.8 0.4 0.63 10.1 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG22749.1 - 0.13 11.5 0.4 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DUF3328 PF11807.8 OAG22751.1 - 2.4e-32 112.5 0.0 3.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAG22752.1 - 6.4e-26 91.5 7.2 4.7e-25 88.7 7.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 OAG22753.1 - 7.6e-31 108.1 10.3 1.3e-30 107.4 10.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_3_C PF01915.22 OAG22754.1 - 2.9e-45 154.7 0.0 4.4e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG22754.1 - 5.3e-27 93.7 2.1 1.1e-26 92.7 2.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 OAG22754.1 - 3e-25 89.3 0.0 5.4e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain RhlB PF12300.8 OAG22754.1 - 0.34 11.0 3.0 0.71 10.0 3.0 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Form_Nir_trans PF01226.17 OAG22755.1 - 6.1e-71 238.5 12.0 7e-71 238.3 12.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter AflR PF08493.10 OAG22755.1 - 0.073 12.5 1.2 0.099 12.1 1.2 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein RDD PF06271.12 OAG22755.1 - 3.1 8.0 9.3 0.043 14.0 1.7 1.8 2 1 0 2 2 2 0 RDD family MutS_V PF00488.21 OAG22756.1 - 2.7e-81 272.1 0.3 6.4e-81 270.9 0.3 1.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG22756.1 - 4.7e-37 128.1 0.6 1.3e-36 126.6 0.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 OAG22756.1 - 2.8e-20 73.0 2.5 1.4e-19 70.7 0.1 3.0 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 OAG22756.1 - 5.2e-19 68.4 3.1 1.5e-18 66.9 3.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 OAG22756.1 - 1.7e-18 66.9 0.0 2.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain I DUF148 PF02520.17 OAG22756.1 - 0.018 15.1 8.4 0.76 9.9 0.5 3.3 4 0 0 4 4 4 0 Domain of unknown function DUF148 IFN-gamma PF00714.17 OAG22756.1 - 0.073 12.9 0.0 0.073 12.9 0.0 2.5 3 1 0 3 3 3 0 Interferon gamma KinB_sensor PF16767.5 OAG22756.1 - 0.82 10.1 4.4 0.6 10.6 0.1 2.6 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB Ist1 PF03398.14 OAG22757.1 - 1.7e-56 190.6 5.9 2.3e-56 190.2 5.9 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway HET PF06985.11 OAG22758.1 - 1.1e-12 48.5 4.9 8.9e-09 35.9 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mucin15 PF15672.5 OAG22759.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Alpha_GJ PF03229.13 OAG22759.1 - 0.025 15.1 1.1 0.057 14.0 1.1 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J SKG6 PF08693.10 OAG22759.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rick_17kDa_Anti PF05433.15 OAG22759.1 - 5.2 7.0 17.2 0.13 12.2 5.0 3.2 3 0 0 3 3 3 0 Glycine zipper 2TM domain Caps_synth PF05704.12 OAG22760.1 - 7.4e-13 48.5 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG22760.1 - 2.5e-06 28.0 0.1 4.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG22760.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Tannase PF07519.11 OAG22761.1 - 2.9e-91 306.7 0.0 3.3e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG22761.1 - 0.00025 20.6 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG22761.1 - 0.06 12.6 0.0 5.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 OAG22762.1 - 3e-32 111.9 27.0 1e-31 110.2 26.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ECH_1 PF00378.20 OAG22763.1 - 2.4e-39 135.2 0.0 2.8e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG22763.1 - 3.1e-13 49.9 0.0 3.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 OAG22764.1 - 2e-61 207.9 0.0 2.4e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG22764.1 - 6.7e-20 71.9 0.1 1.6e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBM_48 PF02922.18 OAG22764.1 - 0.036 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Fungal_trans PF04082.18 OAG22765.1 - 2e-21 76.2 0.6 3.9e-21 75.3 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22765.1 - 4.4e-09 36.3 10.3 9e-09 35.3 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 OAG22767.1 - 2.9e-07 30.1 0.2 4.7e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DnaJ_C PF01556.18 OAG22768.1 - 1.6e-37 128.9 0.1 2.4e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG22768.1 - 2.2e-20 72.5 4.7 3.9e-20 71.7 4.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG22768.1 - 4.4e-13 49.4 19.7 7.7e-13 48.6 19.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG22768.1 - 0.00056 19.8 4.0 0.00056 19.8 4.0 2.8 2 1 1 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG22768.1 - 0.44 10.6 6.6 3.1 7.8 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1c PF00749.21 OAG22769.1 - 2.9e-91 305.7 0.0 3.6e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain JAB PF01398.21 OAG22770.1 - 1.3e-30 105.8 0.3 3.3e-30 104.5 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAG22770.1 - 5.3e-21 75.3 0.9 1.4e-20 74.0 0.9 1.8 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAG22770.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OAG22770.1 - 0.0067 16.5 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) HHH_4 PF14490.6 OAG22770.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain ATG16 PF08614.11 OAG22771.1 - 6.5e-51 173.4 24.8 7.6e-51 173.2 24.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Med21 PF11221.8 OAG22771.1 - 0.0061 16.8 8.3 0.0061 16.8 8.3 2.3 1 1 1 2 2 2 1 Subunit 21 of Mediator complex FlaC_arch PF05377.11 OAG22771.1 - 0.0099 16.3 11.9 0.46 10.9 0.6 2.6 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 OAG22771.1 - 0.014 14.8 15.9 0.021 14.3 15.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 OAG22771.1 - 0.023 14.7 7.1 0.023 14.7 7.1 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OAG22771.1 - 0.027 14.2 16.7 0.18 11.6 4.9 2.7 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 OAG22771.1 - 0.028 14.9 3.7 0.028 14.9 3.7 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF812 PF05667.11 OAG22771.1 - 0.047 12.6 18.9 0.056 12.3 18.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 OAG22771.1 - 0.049 13.7 26.7 0.036 14.1 9.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OAG22771.1 - 0.12 11.8 21.5 0.35 10.2 21.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 OAG22771.1 - 0.18 12.3 31.1 5.1 7.6 12.8 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Macoilin PF09726.9 OAG22771.1 - 0.31 9.5 17.8 0.38 9.3 17.8 1.1 1 0 0 1 1 1 0 Macoilin family HAUS-augmin3 PF14932.6 OAG22771.1 - 0.39 10.3 21.6 0.017 14.7 10.9 2.8 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 ERM PF00769.19 OAG22771.1 - 0.51 10.1 30.7 0.44 10.3 3.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CagE_TrbE_VirB PF03135.14 OAG22771.1 - 0.55 10.3 3.2 3.6 7.6 3.2 1.8 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system UPF0242 PF06785.11 OAG22771.1 - 0.58 10.2 19.1 5.9 6.9 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAG22771.1 - 0.74 8.6 24.1 0.34 9.8 20.6 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 OAG22771.1 - 0.84 9.8 10.3 0.24 11.6 1.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 OAG22771.1 - 0.99 10.1 18.5 4.5 8.0 8.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 OAG22771.1 - 1 8.6 21.1 0.047 13.0 13.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OAG22771.1 - 2 9.1 20.9 0.22 12.2 6.8 3.1 2 1 1 3 3 3 0 SlyX TolA_bind_tri PF16331.5 OAG22771.1 - 2.3 8.3 19.2 9.6 6.4 8.1 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation BRE1 PF08647.11 OAG22771.1 - 2.5 8.3 24.0 0.057 13.5 5.4 2.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2959 PF11172.8 OAG22771.1 - 3.4 7.8 14.8 0.18 12.0 1.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) V_ATPase_I PF01496.19 OAG22771.1 - 5 4.9 9.3 5.3 4.8 9.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 OAG22771.1 - 7.1 6.7 30.6 0.093 12.8 9.4 3.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 OAG22771.1 - 7.1 5.4 7.0 7.5 5.3 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CC2-LZ PF16516.5 OAG22771.1 - 8.1 6.9 20.2 8.1 6.9 9.9 3.2 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF883 PF05957.13 OAG22771.1 - 8.9 7.0 19.0 12 6.5 0.7 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) IF3_C PF00707.22 OAG22772.1 - 9.7e-06 25.5 0.1 1.9e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 OAG22772.1 - 0.00017 21.8 0.4 0.00063 20.0 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 OAG22772.1 - 0.00039 20.1 0.1 0.0035 17.1 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Ribosomal_L4 PF00573.22 OAG22773.1 - 2.8e-48 164.2 0.1 1.4e-47 161.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family PBP PF01161.20 OAG22774.1 - 7.6e-09 36.0 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mei4 PF13971.6 OAG22775.1 - 0.0028 17.2 0.0 0.0051 16.4 0.0 1.5 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 Hydantoinase_B PF02538.14 OAG22776.1 - 2.6e-199 662.9 0.7 3.4e-199 662.5 0.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG22776.1 - 4.5e-98 328.1 0.2 4.3e-97 324.9 0.1 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG22776.1 - 6.8e-59 198.6 0.3 3.2e-57 193.1 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Aminotran_1_2 PF00155.21 OAG22777.1 - 5.1e-15 55.5 0.0 9.6e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG22777.1 - 0.047 12.5 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase GATase PF00117.28 OAG22778.1 - 6e-07 29.4 0.0 8.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAG22778.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAG22779.1 - 1.7e-35 122.6 25.4 2.4e-35 122.1 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG22779.1 - 0.00026 20.4 2.3 0.00026 20.4 2.3 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ICL PF00463.21 OAG22780.1 - 1.9e-118 396.2 1.5 2.4e-118 396.0 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG22780.1 - 5.2e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.18 OAG22781.1 - 6e-15 55.0 6.4 9.1e-15 54.4 6.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22781.1 - 1.2e-06 28.5 12.3 2.5e-06 27.5 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SBP_bac_6 PF13343.6 OAG22782.1 - 5.7e-09 35.7 0.3 2.4e-08 33.7 0.3 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 OAG22782.1 - 2.7e-07 30.6 0.1 3.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 OAG22782.1 - 5e-06 26.7 4.3 1.4e-05 25.3 4.2 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 OAG22782.1 - 5.1e-06 26.5 3.1 9.9e-06 25.6 3.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein BTB PF00651.31 OAG22783.1 - 3.5e-15 56.2 0.1 7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain CDC45 PF02724.14 OAG22784.1 - 0.92 7.7 4.5 1.2 7.3 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG22784.1 - 1.1 7.2 10.7 1.5 6.8 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OAG22784.1 - 1.5 8.8 4.7 3.4 7.7 4.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 OAG22784.1 - 2.2 6.4 5.2 2.8 6.0 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAG22784.1 - 4.2 6.6 14.9 5.9 6.1 14.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OAG22784.1 - 5.9 5.9 14.2 8.8 5.3 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2076 PF09849.9 OAG22784.1 - 7.3 6.5 9.6 12 5.8 9.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CENP-B_dimeris PF09026.10 OAG22784.1 - 8.9 6.8 18.7 17 5.9 18.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IPPT PF01715.17 OAG22786.1 - 2.4e-65 220.5 0.1 3.3e-65 220.1 0.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 OAG22786.1 - 3.2e-05 23.4 0.0 8.2e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 OAG22786.1 - 0.00017 21.8 0.4 0.0024 18.0 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG22786.1 - 0.0086 16.6 0.8 0.18 12.3 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OAG22786.1 - 0.028 14.8 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_jaz PF12171.8 OAG22786.1 - 0.028 14.7 0.1 0.052 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.27 OAG22786.1 - 0.039 14.5 0.2 0.12 12.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 OAG22787.1 - 5e-17 62.7 0.0 4.2e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG22787.1 - 1.2e-10 41.7 1.7 0.00012 22.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG22787.1 - 0.00038 20.2 0.4 0.0041 16.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 OAG22787.1 - 0.00057 19.4 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 OAG22787.1 - 0.0019 15.8 0.0 0.0025 15.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 OAG22787.1 - 0.0051 17.3 0.1 0.0088 16.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OAG22787.1 - 0.014 15.2 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OAG22787.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 OAG22787.1 - 0.018 14.6 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG22787.1 - 0.02 15.1 0.3 0.037 14.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG22787.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.22 OAG22787.1 - 0.038 13.6 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 OAG22787.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OAG22787.1 - 0.11 12.9 0.6 0.16 12.4 0.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OAG22787.1 - 0.12 12.8 0.1 0.64 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 OAG22787.1 - 0.13 11.7 0.4 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_13 PF13166.6 OAG22787.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG22787.1 - 0.18 12.0 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG22787.1 - 0.21 11.9 0.7 0.51 10.6 0.2 1.8 2 0 0 2 2 2 0 AAA domain GH131_N PF18271.1 OAG22788.1 - 2.1e-80 270.1 1.4 2.4e-80 269.9 1.4 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 OAG22788.1 - 0.074 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Fringe PF02434.16 OAG22789.1 - 1.9e-08 34.1 0.1 8.8e-08 31.9 0.1 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAG22789.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase PAN_4 PF14295.6 OAG22789.1 - 0.024 14.5 1.6 0.049 13.5 1.6 1.5 1 0 0 1 1 1 0 PAN domain OTU PF02338.19 OAG22789.1 - 0.17 12.4 0.3 17 5.9 0.0 2.4 2 0 0 2 2 2 0 OTU-like cysteine protease Rootletin PF15035.6 OAG22791.1 - 0.0044 17.1 3.4 0.0059 16.6 3.4 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Helo_like_N PF17111.5 OAG22791.1 - 0.023 14.1 0.4 0.042 13.2 0.2 1.5 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins ABC_tran_CTD PF16326.5 OAG22791.1 - 0.065 13.5 2.5 0.18 12.0 0.2 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Di19_C PF14571.6 OAG22791.1 - 0.066 13.7 1.2 0.11 13.1 0.7 1.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF4094 PF13334.6 OAG22791.1 - 0.2 12.1 1.0 0.28 11.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4164 PF13747.6 OAG22791.1 - 0.45 10.8 7.5 0.86 9.9 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) NTP_transf_9 PF04248.12 OAG22792.1 - 7.3e-36 121.9 0.1 2.7e-32 110.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Polysacc_deac_1 PF01522.21 OAG22793.1 - 4.4e-15 55.7 0.0 9.3e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HAT_KAT11 PF08214.11 OAG22794.1 - 0.062 12.6 0.1 0.07 12.4 0.1 1.0 1 0 0 1 1 1 0 Histone acetylation protein FlxA PF14282.6 OAG22794.1 - 1.2 9.1 12.3 3.4 7.7 12.3 1.8 1 1 0 1 1 1 0 FlxA-like protein FAD_binding_4 PF01565.23 OAG22795.1 - 1.6e-30 105.7 4.6 6.4e-30 103.7 5.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG22795.1 - 5.5e-09 36.0 2.8 1.1e-08 35.0 2.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG22795.1 - 0.05 13.0 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf_CCCH_4 PF18345.1 OAG22796.1 - 0.00066 19.6 2.2 0.0013 18.8 2.2 1.5 1 0 0 1 1 1 1 Zinc finger domain Zn_clus PF00172.18 OAG22796.1 - 0.055 13.6 7.0 0.16 12.1 7.0 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TolA_bind_tri PF16331.5 OAG22796.1 - 0.11 12.6 0.2 0.11 12.6 0.2 4.2 4 0 0 4 4 4 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 OAG22796.1 - 6.7 6.8 18.9 2.5 8.2 0.3 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG22 PF11700.8 OAG22797.1 - 7e-140 466.8 21.1 8.1e-140 466.6 21.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG22797.1 - 3.1e-12 46.1 25.0 1.7e-07 30.5 5.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily HALZ PF02183.18 OAG22798.1 - 0.31 11.3 14.5 0.44 10.8 3.2 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper APG6_N PF17675.1 OAG22798.1 - 0.7 10.4 10.5 1 9.9 10.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Choline_kinase PF01633.20 OAG22799.1 - 0.007 16.0 0.5 0.094 12.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase GspH PF12019.8 OAG22799.1 - 0.053 14.0 0.2 0.35 11.3 0.1 2.2 2 0 0 2 2 2 0 Type II transport protein GspH F-box-like PF12937.7 OAG22800.1 - 4.4e-05 23.3 0.1 0.00013 21.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like Tyr-DNA_phospho PF06087.12 OAG22801.1 - 4e-83 279.7 0.0 5.2e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 OAG22801.1 - 5.6e-11 41.6 13.0 5e-06 26.1 1.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 OAG22801.1 - 9.7e-05 22.3 0.0 0.058 13.3 0.0 2.6 3 0 0 3 3 3 2 PLD-like domain RAP80_UIM PF18282.1 OAG22801.1 - 0.5 10.2 2.4 4.8 7.0 0.2 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Urm1 PF09138.11 OAG22803.1 - 3.8e-31 107.3 0.0 4.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OAG22803.1 - 0.0002 21.9 0.0 0.00024 21.7 0.0 1.1 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 OAG22804.1 - 1.3e-43 146.1 21.7 3.6e-08 33.9 0.2 12.5 12 1 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG22804.1 - 4.4e-06 26.9 5.4 2.7 8.3 0.1 7.6 7 3 2 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG22804.1 - 0.0041 16.1 0.0 1 8.3 0.0 3.6 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MARVEL PF01284.23 OAG22805.1 - 0.042 13.9 5.5 0.077 13.0 5.2 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF5305 PF17231.2 OAG22805.1 - 0.15 11.5 0.0 0.67 9.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF2754 PF10953.8 OAG22805.1 - 0.65 10.3 7.6 24 5.3 7.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2754) Fig1 PF12351.8 OAG22805.1 - 2.1 8.2 5.6 1.7 8.6 3.7 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3328 PF11807.8 OAG22807.1 - 2.7e-30 105.8 0.3 3.4e-30 105.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UEV PF05743.13 OAG22809.1 - 5.7e-38 129.5 0.0 8.9e-38 128.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OAG22809.1 - 4.2e-23 81.1 0.0 7.7e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Vps23 core domain ArgJ PF01960.18 OAG22809.1 - 0.19 10.4 0.2 0.26 10.0 0.2 1.1 1 0 0 1 1 1 0 ArgJ family Snapin_Pallidin PF14712.6 OAG22809.1 - 0.39 11.2 3.5 0.44 11.0 2.2 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Aminotran_5 PF00266.19 OAG22810.1 - 4.6e-94 315.4 0.0 5.5e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG22810.1 - 4.6e-06 26.1 0.1 6.9e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG22810.1 - 0.00015 21.2 0.3 0.00048 19.6 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 OAG22810.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 OAG22811.1 - 1.5e-60 204.8 8.9 2e-60 204.4 8.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAG22811.1 - 2.3e-14 52.7 0.1 4.4e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG22811.1 - 4.3e-09 36.1 0.1 9.1e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG22811.1 - 6.8e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TMPIT PF07851.13 OAG22811.1 - 0.022 14.0 0.4 0.022 14.0 0.4 1.9 1 1 1 2 2 2 0 TMPIT-like protein BAR_3 PF16746.5 OAG22811.1 - 0.75 9.4 11.7 1.9 8.1 11.7 1.9 1 1 0 1 1 1 0 BAR domain of APPL family APG6_N PF17675.1 OAG22811.1 - 1.1 9.8 9.7 7.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Radial_spoke_3 PF06098.11 OAG22811.1 - 1.2 8.3 10.4 0.12 11.6 2.5 2.2 2 0 0 2 2 2 0 Radial spoke protein 3 Aida_N PF08910.10 OAG22811.1 - 2.9 8.4 4.8 2.7 8.4 0.7 2.9 3 1 0 3 3 3 0 Aida N-terminus DSBA PF01323.20 OAG22812.1 - 4.7e-23 82.0 0.1 5.2e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Peripla_BP_2 PF01497.18 OAG22812.1 - 0.076 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Lambda_CIII PF02061.16 OAG22813.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Lambda Phage CIII QCR10 PF09796.9 OAG22814.1 - 0.2 11.8 1.6 8.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Sugar_tr PF00083.24 OAG22816.1 - 9.9e-84 281.8 8.5 1.6e-83 281.1 8.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_cyclohydro2 PF00925.20 OAG22816.1 - 7.2e-56 188.3 0.0 1.4e-55 187.3 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II MFS_1 PF07690.16 OAG22816.1 - 1.2e-34 119.8 50.8 2.4e-31 109.0 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG22816.1 - 5.1e-05 22.7 2.8 5.1e-05 22.7 2.8 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 OAG22817.1 - 2e-64 217.5 0.0 2.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22817.1 - 3.4e-31 108.5 0.0 5.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG22817.1 - 0.0008 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG22817.1 - 0.0079 16.1 0.0 0.16 11.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG22817.1 - 0.04 13.5 0.1 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CBF PF03914.17 OAG22817.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 CBF/Mak21 family CAP PF00188.26 OAG22818.1 - 1.6e-19 71.0 1.4 2.3e-19 70.5 1.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Heme_oxygenase PF01126.20 OAG22819.1 - 5.4e-12 45.9 0.0 7.2e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase zf-C2H2_4 PF13894.6 OAG22821.1 - 0.00047 20.8 31.0 0.84 10.6 0.5 7.4 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG22821.1 - 0.0029 18.0 44.8 0.03 14.8 0.7 7.5 7 1 0 7 7 7 4 Zinc finger, C2H2 type IBR PF01485.21 OAG22821.1 - 0.0036 17.5 15.0 4 7.7 0.2 4.3 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C4pol PF14260.6 OAG22821.1 - 5.1 7.6 9.2 1.3 9.6 0.6 2.7 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C2HE PF16278.5 OAG22821.1 - 8.7 6.9 7.8 2.8 8.5 4.3 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Fic PF02661.18 OAG22822.1 - 0.075 13.9 0.6 3.7 8.5 0.1 3.2 3 0 0 3 3 3 0 Fic/DOC family DUF905 PF06006.12 OAG22822.1 - 0.11 12.5 0.2 3.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF905) UQ_con PF00179.26 OAG22823.1 - 2.6e-20 72.5 0.0 3.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COesterase PF00135.28 OAG22825.1 - 1.9e-85 287.7 0.0 2.3e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG22825.1 - 0.0011 18.5 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG22825.1 - 0.0022 17.9 0.1 0.01 15.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 OAG22826.1 - 1.6e-53 182.1 0.0 2.1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 OAG22827.1 - 1.6e-48 165.6 0.0 2.1e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG22827.1 - 5.5e-28 98.3 0.0 1e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG22827.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG22827.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG22827.1 - 0.052 13.8 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG22827.1 - 0.071 12.0 0.2 0.15 10.9 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 OAG22827.1 - 0.094 11.8 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain B3_4 PF03483.17 OAG22828.1 - 6.6e-20 71.5 0.0 8.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain Surface_antigen PF11054.8 OAG22828.1 - 0.053 13.2 0.1 0.08 12.6 0.1 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Rieske PF00355.26 OAG22829.1 - 2.9e-08 33.5 0.1 4.4e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OAG22829.1 - 2.2e-06 27.5 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Glyco_hydr_30_2 PF14587.6 OAG22830.1 - 1.6e-14 54.3 3.3 2.2e-13 50.6 0.1 2.8 3 0 0 3 3 3 2 O-Glycosyl hydrolase family 30 Glyco_hydro_32N PF00251.20 OAG22831.1 - 2.1e-79 267.3 1.4 2.8e-79 266.9 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAG22831.1 - 1.6e-09 38.0 0.1 3.9e-09 36.7 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_4 PF15892.5 OAG22832.1 - 7.9e-73 245.2 4.1 1.3e-72 244.5 4.1 1.3 1 0 0 1 1 1 1 BNR repeat-containing family member BNR_2 PF13088.6 OAG22832.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 BNR repeat-like domain Peptidase_M14 PF00246.24 OAG22833.1 - 8.2e-14 52.1 0.0 2.6e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase DLH PF01738.18 OAG22834.1 - 2.5e-18 66.4 0.0 3.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAG22834.1 - 0.00022 21.9 0.0 0.00028 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAG22834.1 - 0.13 12.1 0.0 1.9 8.4 0.0 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GTP_cyclohydroI PF01227.22 OAG22835.1 - 8.4e-74 246.9 0.1 1.1e-73 246.4 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OAG22835.1 - 0.0017 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.6 OAG22835.1 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.25 OAG22837.1 - 5.3e-72 242.3 0.4 7.2e-72 241.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22837.1 - 7.2e-36 123.8 0.0 1.2e-35 123.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG22837.1 - 0.00022 20.7 0.4 0.00053 19.4 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG22837.1 - 0.00088 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG22837.1 - 0.0014 17.6 0.1 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG22837.1 - 0.025 13.4 0.9 0.037 12.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG22837.1 - 0.094 12.6 2.5 0.096 12.6 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATP-synt_B PF00430.18 OAG22837.1 - 1.6 8.9 9.1 2.6 8.1 9.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CENP-F_leu_zip PF10473.9 OAG22839.1 - 0.0025 17.8 1.0 0.0025 17.8 1.0 6.5 1 1 6 7 7 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OAG22839.1 - 0.0063 15.4 61.0 0.47 9.3 4.7 4.6 1 1 4 5 5 5 4 Spc7 kinetochore protein HOOK PF05622.12 OAG22839.1 - 0.011 14.0 61.1 0.0036 15.5 33.6 3.1 1 1 1 2 2 2 0 HOOK protein YabA PF06156.13 OAG22839.1 - 0.017 15.7 49.0 1.3 9.7 0.9 7.3 1 1 5 6 6 5 0 Initiation control protein YabA ERM PF00769.19 OAG22839.1 - 0.04 13.7 70.6 0.38 10.5 6.2 4.4 1 1 3 4 4 4 0 Ezrin/radixin/moesin family Mvb12 PF09452.10 OAG22839.1 - 0.064 13.7 0.5 0.56 10.7 0.1 2.8 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 ATG16 PF08614.11 OAG22839.1 - 0.12 12.6 73.6 0.039 14.2 3.0 6.0 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OAG22839.1 - 0.16 12.5 77.5 0.52 10.8 9.4 6.0 1 1 5 6 6 6 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 OAG22839.1 - 0.71 8.7 73.8 0.12 11.2 20.3 3.3 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.18 OAG22839.1 - 1.1 9.5 0.0 1.1 9.5 0.0 6.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 OAG22839.1 - 1.4 9.0 7.4 4 7.5 0.1 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 OAG22839.1 - 1.8 9.0 27.3 0.19 12.2 3.6 5.8 3 2 4 7 7 7 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 OAG22839.1 - 2.1 8.6 39.2 1.5 9.1 0.2 6.0 3 2 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 OAG22839.1 - 3.6 7.4 59.6 1.6 8.6 12.7 5.4 1 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 OAG22839.1 - 4.5 7.4 63.4 0.23 11.5 1.5 6.3 1 1 5 6 6 6 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 OAG22839.1 - 8.9 6.9 10.5 1.5e+02 2.9 0.0 5.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Hamartin PF04388.12 OAG22840.1 - 3.5 6.2 7.3 1.5 7.4 5.4 1.4 1 1 0 1 1 1 0 Hamartin protein AT_hook PF02178.19 OAG22840.1 - 6.6 7.0 58.0 0.15 12.0 3.7 7.2 8 0 0 8 8 8 0 AT hook motif ABC2_membrane PF01061.24 OAG22841.1 - 5.6e-84 280.8 44.6 7.7e-46 156.2 19.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAG22841.1 - 1.9e-39 135.3 0.0 4.2e-19 69.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG22841.1 - 4.7e-23 80.9 8.7 4.7e-23 80.9 0.0 3.2 3 0 0 3 3 2 1 CDR ABC transporter AAA_16 PF13191.6 OAG22841.1 - 1.9e-07 31.6 0.1 0.0016 18.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 OAG22841.1 - 2e-07 30.5 41.8 0.00029 20.1 17.8 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 OAG22841.1 - 1.3e-05 25.7 0.4 3.3e-05 24.4 0.4 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 OAG22841.1 - 5.6e-05 23.4 0.1 0.67 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG22841.1 - 0.0006 19.7 0.1 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG22841.1 - 0.00081 19.1 1.1 0.084 12.6 0.1 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG22841.1 - 0.0011 19.6 0.0 1.4 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 OAG22841.1 - 0.002 17.7 1.0 1.7 8.2 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAG22841.1 - 0.0021 18.2 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG22841.1 - 0.0035 17.0 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG22841.1 - 0.0052 17.0 0.3 0.6 10.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG22841.1 - 0.009 16.4 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 OAG22841.1 - 0.01 15.2 0.1 0.077 12.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 OAG22841.1 - 0.012 14.9 0.7 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OAG22841.1 - 0.013 15.4 0.5 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 OAG22841.1 - 0.05 13.5 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 OAG22841.1 - 0.052 13.3 0.2 5.9 6.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG22841.1 - 0.09 12.5 0.1 10 5.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 OAG22841.1 - 0.22 11.3 1.4 9 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 OAG22841.1 - 0.42 10.2 2.0 30 4.2 0.3 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 OAG22841.1 - 2 7.6 16.7 0.36 10.0 6.5 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein TPR_2 PF07719.17 OAG22843.1 - 1.2e-10 40.7 3.2 0.00037 20.4 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF4470 PF14737.6 OAG22843.1 - 3.8e-09 36.6 0.0 9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_1 PF00515.28 OAG22843.1 - 2.2e-07 30.4 2.2 0.0012 18.6 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG22843.1 - 3.6e-06 27.4 3.2 0.05 14.1 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22843.1 - 4.3e-05 23.4 1.1 0.56 10.6 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG22843.1 - 0.00046 19.8 0.8 0.00046 19.8 0.8 2.5 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 OAG22843.1 - 0.00082 19.9 1.7 1 10.1 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22843.1 - 0.001 19.3 1.0 0.012 15.9 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22843.1 - 0.0057 17.4 0.2 8 7.6 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22843.1 - 0.0062 17.2 0.2 0.095 13.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG22843.1 - 0.24 11.5 1.0 55 4.1 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG22843.1 - 0.39 11.0 1.6 1.9 8.7 1.6 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 adh_short PF00106.25 OAG22844.1 - 5.2e-46 156.6 0.0 6.8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22844.1 - 1.5e-30 106.5 0.0 1.9e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22844.1 - 1.9e-10 41.0 0.0 2.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG22844.1 - 0.02 15.2 0.1 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG22844.1 - 0.028 13.6 0.0 0.066 12.3 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 OAG22844.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4079 PF13301.6 OAG22845.1 - 0.48 10.6 6.9 0.046 13.9 2.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Methyltransf_2 PF00891.18 OAG22846.1 - 1.5e-19 70.2 0.0 2.3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain LSM PF01423.22 OAG22847.1 - 1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG22847.1 - 5.4e-05 23.3 0.0 6.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF4242 PF14026.6 OAG22847.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) FBA PF04300.13 OAG22848.1 - 0.0054 16.4 0.3 0.0086 15.8 0.3 1.4 1 0 0 1 1 1 1 F-box associated region WD40 PF00400.32 OAG22850.1 - 2.1e-47 158.1 25.3 1.9e-09 38.0 0.2 12.5 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.12 OAG22850.1 - 1e-24 86.9 0.0 1.6e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAG22850.1 - 1.2e-22 80.1 0.0 0.017 15.4 0.0 10.0 5 2 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG22850.1 - 5.1e-10 38.8 0.9 0.31 10.0 0.0 6.4 4 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG22850.1 - 3.9e-06 26.9 0.4 0.012 15.5 0.1 5.2 5 1 1 7 7 7 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG22850.1 - 4.5e-05 22.3 5.0 0.48 9.0 0.0 4.9 3 2 1 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG22850.1 - 0.00058 19.3 0.0 1.1 8.5 0.0 3.9 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 OAG22850.1 - 0.00089 18.7 0.4 1.6 8.0 0.1 4.0 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 OAG22850.1 - 0.0023 16.1 0.0 0.059 11.4 0.0 2.1 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.12 OAG22850.1 - 0.12 12.4 2.3 3.7 7.6 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Septin PF00735.18 OAG22851.1 - 3.5e-112 374.3 0.1 4.6e-112 373.9 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG22851.1 - 2.3e-07 30.9 0.0 4.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG22851.1 - 4.8e-06 26.6 0.1 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG22851.1 - 1.3e-05 24.9 3.3 9.2e-05 22.1 0.5 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAG22851.1 - 0.00076 19.8 0.2 0.0033 17.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 OAG22851.1 - 0.0031 17.0 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 OAG22851.1 - 0.0072 16.5 0.1 0.016 15.5 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 OAG22851.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 OAG22851.1 - 0.013 15.9 0.2 0.043 14.2 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OAG22851.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 OAG22851.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FOXP-CC PF16159.5 OAG22851.1 - 0.026 15.1 1.0 0.026 15.1 1.0 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain Val_tRNA-synt_C PF10458.9 OAG22851.1 - 0.033 14.5 3.6 0.035 14.4 0.2 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ras PF00071.22 OAG22851.1 - 0.033 13.8 0.7 0.094 12.3 0.4 1.9 2 1 0 2 2 2 0 Ras family KAP_NTPase PF07693.14 OAG22851.1 - 0.035 13.3 0.0 0.048 12.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 OAG22851.1 - 0.056 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 OAG22851.1 - 0.064 13.8 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 OAG22851.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 OAG22851.1 - 0.086 11.9 0.2 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 OAG22851.1 - 0.11 12.2 0.3 4 7.2 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OAG22851.1 - 0.17 11.7 0.4 13 5.5 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OAG22851.1 - 0.43 10.6 5.9 3.1 7.8 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Jnk-SapK_ap_N PF09744.9 OAG22851.1 - 0.49 10.6 8.7 0.12 12.6 4.7 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 OAG22851.1 - 2 9.0 8.4 0.8 10.4 3.4 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fimbrial_PilY2 PF14481.6 OAG22852.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Glyco_hydro_61 PF03443.14 OAG22853.1 - 4.9e-60 203.0 0.0 5.9e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDH-cyt PF16010.5 OAG22854.1 - 3.5e-48 163.7 2.1 7.1e-48 162.7 2.1 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG22854.1 - 1.8e-28 99.8 0.1 4.6e-28 98.4 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG22854.1 - 1.9e-19 70.6 0.1 3.9e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 OAG22854.1 - 1.4e-12 47.3 7.6 4.9e-12 45.6 7.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 OAG22854.1 - 6.7e-06 25.4 0.6 9.3e-05 21.7 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG22854.1 - 0.0022 17.3 0.0 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG22854.1 - 0.0037 17.8 0.0 0.78 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22854.1 - 0.0044 17.2 0.3 0.024 14.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG22854.1 - 0.0046 15.7 0.1 0.007 15.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG22854.1 - 0.055 12.7 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG22854.1 - 0.059 12.7 0.1 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DOMON PF03351.17 OAG22854.1 - 0.081 13.1 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 DOMON domain Lycopene_cycl PF05834.12 OAG22854.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PSI PF01437.25 OAG22855.1 - 5e-05 23.8 6.6 0.0001 22.8 6.6 1.5 1 0 0 1 1 1 1 Plexin repeat TB2_DP1_HVA22 PF03134.19 OAG22855.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family PSI_integrin PF17205.3 OAG22855.1 - 0.42 10.4 7.3 0.85 9.4 7.3 1.5 1 0 0 1 1 1 0 Integrin plexin domain HTH_AsnC-type PF13404.6 OAG22856.1 - 0.0017 18.2 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain UBA_4 PF14555.6 OAG22856.1 - 0.0041 16.9 0.8 0.0074 16.1 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain HTH_24 PF13412.6 OAG22856.1 - 0.098 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 OAG22858.1 - 3.5e-26 92.0 55.5 1.8e-25 89.6 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1e PF01406.19 OAG22859.1 - 2.7e-117 391.4 0.0 5.3e-117 390.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAG22859.1 - 0.0061 15.4 0.3 1.3 7.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 OAG22859.1 - 0.037 12.9 0.0 0.037 12.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain GCD14 PF08704.10 OAG22860.1 - 1.4e-61 208.3 1.2 3.9e-21 75.8 0.0 4.1 3 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit PhoD PF09423.10 OAG22861.1 - 1.1e-41 143.0 0.0 2.2e-41 142.0 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase HET PF06985.11 OAG22862.1 - 1.3e-10 41.8 4.1 1.8e-09 38.1 1.3 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 OAG22864.1 - 3.7e-25 88.4 0.0 5.5e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG22864.1 - 1.1e-05 25.2 3.6 1.2e-05 25.2 0.5 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Nop10p PF04135.12 OAG22865.1 - 1.1e-18 67.0 0.8 1.3e-18 66.7 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF2076 PF09849.9 OAG22866.1 - 0.07 13.2 1.0 0.089 12.8 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FUSC PF04632.12 OAG22867.1 - 0.0021 16.7 17.5 0.0021 16.7 17.5 4.5 1 1 3 4 4 4 1 Fusaric acid resistance protein family GAS PF13851.6 OAG22867.1 - 0.036 13.4 106.4 0.27 10.5 10.1 6.8 2 2 5 7 7 7 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 OAG22867.1 - 3.9 7.0 108.0 0.0093 15.6 39.0 5.7 1 1 2 4 4 4 0 Intermediate filament protein DUF3293 PF11697.8 OAG22867.1 - 6.6 7.3 7.5 10 6.7 0.7 4.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) ACT_7 PF13840.6 OAG22868.1 - 1.2e-26 92.3 0.0 2.1e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 ACT domain CorA PF01544.18 OAG22869.1 - 1.2 8.4 4.7 4.8 6.4 4.1 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein His_Phos_1 PF00300.22 OAG22870.1 - 1.9e-15 57.1 0.0 2.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TT1725 PF18324.1 OAG22870.1 - 0.047 13.8 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein TT1725 Arylsulfotran_2 PF14269.6 OAG22871.1 - 9.4e-94 314.1 0.4 1.3e-93 313.6 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG22871.1 - 2.3e-18 66.3 1.3 4.6e-17 62.0 1.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PD40 PF07676.12 OAG22872.1 - 2.5e-49 164.3 31.7 2.2e-08 33.8 0.8 9.9 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 OAG22872.1 - 3.6e-11 42.4 8.8 0.0012 17.7 0.1 6.7 3 2 3 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 OAG22872.1 - 3e-09 36.5 0.0 0.0068 15.7 0.0 5.0 4 1 1 5 5 5 2 Domain of unknown function (DUF5050) SGL PF08450.12 OAG22872.1 - 9.9e-06 25.3 4.1 0.014 15.0 0.3 4.5 2 2 2 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Pectate_lyase22 PF14583.6 OAG22872.1 - 0.0016 17.2 0.2 0.055 12.1 0.0 3.4 2 2 1 3 3 3 1 Oligogalacturonate lyase Gmad1 PF10647.9 OAG22872.1 - 0.0025 17.6 0.1 0.37 10.5 0.1 3.5 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain DUF3748 PF12566.8 OAG22872.1 - 0.047 13.7 0.7 4.3 7.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3748) DUF1513 PF07433.11 OAG22872.1 - 0.051 12.7 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) WD40 PF00400.32 OAG22872.1 - 0.41 11.6 8.7 14 6.7 0.1 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat adh_short PF00106.25 OAG22873.1 - 1.3e-30 106.4 0.0 3e-30 105.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22873.1 - 4.9e-21 75.4 0.0 7e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22873.1 - 3.1e-11 43.5 0.1 4.7e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG22873.1 - 5.9e-07 29.2 0.0 7.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG22873.1 - 0.00091 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG22873.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG22873.1 - 0.095 11.8 0.0 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PALP PF00291.25 OAG22874.1 - 5.5e-35 121.2 0.0 1.1e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 OAG22874.1 - 7.3e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 OAG22875.1 - 8e-43 146.7 49.4 6e-38 130.7 48.8 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG22875.1 - 8.5e-12 44.3 25.8 1.4e-11 43.5 25.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TraE PF05309.11 OAG22875.1 - 0.15 11.4 0.9 0.58 9.5 0.9 2.0 1 0 0 1 1 1 0 TraE protein Ricin_B_lectin PF00652.22 OAG22876.1 - 8.2e-11 42.3 0.8 8.2e-10 39.0 0.7 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OAG22876.1 - 9.2e-09 35.9 2.8 8.4e-07 29.6 0.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like HTH_Tnp_Tc5 PF03221.16 OAG22877.1 - 3.1e-08 33.5 0.0 9.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG22877.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 OAG22877.1 - 0.01 15.6 0.3 0.054 13.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain GntR PF00392.21 OAG22877.1 - 0.058 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Methyltransf_31 PF13847.6 OAG22878.1 - 2.3e-16 60.0 0.0 3.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG22878.1 - 9.4e-16 58.3 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG22878.1 - 5e-13 49.5 0.0 9.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG22878.1 - 2.8e-10 40.3 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG22878.1 - 6.5e-09 36.4 0.0 1e-08 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG22878.1 - 3.9e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 OAG22878.1 - 3.6e-06 26.8 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 OAG22878.1 - 6.5e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 OAG22878.1 - 0.00043 21.3 0.0 0.00092 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OAG22878.1 - 0.0027 17.4 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 OAG22878.1 - 0.0052 16.0 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Amidohydro_2 PF04909.14 OAG22878.1 - 0.0078 16.0 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase CheR PF01739.18 OAG22878.1 - 0.014 14.9 0.0 0.36 10.3 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain GCD14 PF08704.10 OAG22878.1 - 0.014 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 OAG22878.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 OAG22878.1 - 0.17 11.6 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 CorA PF01544.18 OAG22879.1 - 5.6e-07 29.2 5.2 4.9e-06 26.1 0.0 3.0 3 1 0 3 3 3 2 CorA-like Mg2+ transporter protein DUF4503 PF14951.6 OAG22880.1 - 0.0023 16.5 2.8 0.0023 16.5 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) zf-RanBP PF00641.18 OAG22880.1 - 0.074 12.4 2.2 0.074 12.4 2.2 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others HalOD2 PF18547.1 OAG22880.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.7 2 1 1 3 3 3 0 Halobacterial output domain 2 NCD3G PF07562.14 OAG22880.1 - 1.9 8.5 12.8 0.15 12.0 4.5 2.0 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ribosomal_S27e PF01667.17 OAG22880.1 - 2.6 7.8 7.7 12 5.7 7.7 1.9 1 1 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.6 OAG22880.1 - 3.5 7.5 11.2 0.98 9.2 5.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TGT PF01702.18 OAG22882.1 - 3.2e-57 194.3 0.0 4.1e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Phytase PF02333.15 OAG22885.1 - 1.3e-69 235.0 3.5 3e-65 220.7 0.4 2.1 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 OAG22885.1 - 1e-06 29.0 28.2 7.5e-05 23.0 12.0 2.6 2 0 0 2 2 2 2 EGF-like domain Glyco_hydro_7 PF00840.20 OAG22886.1 - 3.9e-193 642.1 13.8 4.4e-193 641.9 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FlaE PF07559.14 OAG22886.1 - 0.0044 17.6 0.4 0.066 13.8 0.1 2.2 1 1 0 2 2 2 1 Flagellar basal body protein FlaE MFS_1 PF07690.16 OAG22887.1 - 1.2e-27 96.8 57.3 4.5e-24 85.0 19.0 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG22887.1 - 4.1e-07 29.2 13.7 4.1e-07 29.2 13.7 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAG22887.1 - 0.0017 16.8 1.5 0.0017 16.8 1.5 3.0 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family PSI_PSAK PF01241.18 OAG22887.1 - 0.033 14.2 1.9 0.092 12.8 0.1 2.7 3 0 0 3 3 3 0 Photosystem I psaG / psaK Fungal_trans PF04082.18 OAG22888.1 - 1.5e-11 43.8 0.0 2.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain P66_CC PF16563.5 OAG22888.1 - 0.75 9.5 3.2 3.2 7.4 1.0 2.5 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Yippee-Mis18 PF03226.14 OAG22889.1 - 6.6e-16 58.4 0.0 7.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAM72 PF14976.6 OAG22889.1 - 0.034 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 FAM72 protein DSBA PF01323.20 OAG22890.1 - 9.8e-55 185.3 0.0 6.1e-30 104.4 0.0 2.7 2 1 0 2 2 2 2 DSBA-like thioredoxin domain zf-RING_2 PF13639.6 OAG22891.1 - 2.9e-07 30.7 7.6 5.7e-07 29.8 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAG22891.1 - 1.9e-05 24.7 4.5 7.2e-05 22.9 4.5 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OAG22891.1 - 0.00054 20.0 1.6 0.0012 18.8 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG22891.1 - 0.013 15.8 6.2 0.03 14.6 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG22891.1 - 0.056 13.3 7.2 0.11 12.4 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) XPC-binding PF09280.11 OAG22891.1 - 0.095 12.4 1.2 0.73 9.6 0.0 3.1 3 0 0 3 3 3 0 XPC-binding domain RINGv PF12906.7 OAG22891.1 - 0.11 12.6 5.9 0.26 11.4 5.9 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 OAG22891.1 - 0.15 11.7 5.2 0.32 10.6 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NIT PF08376.10 OAG22891.1 - 0.16 12.5 0.0 0.16 12.5 0.0 4.5 6 1 0 6 6 6 0 Nitrate and nitrite sensing zf-RING-like PF08746.11 OAG22891.1 - 0.44 10.9 6.0 1 9.8 6.0 1.7 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 OAG22891.1 - 1.1 9.2 5.3 2.4 8.1 5.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_1 PF00130.22 OAG22891.1 - 2.2 8.2 5.5 1.1 9.2 3.2 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 OAG22891.1 - 2.8 7.9 7.3 6 6.8 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD_2 PF06733.15 OAG22892.1 - 2.8e-56 189.9 0.0 4.9e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OAG22892.1 - 2.7e-46 157.7 1.4 4.2e-42 144.0 0.3 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 OAG22892.1 - 2.4e-44 151.5 0.0 9.8e-44 149.5 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 OAG22892.1 - 6e-05 23.1 0.0 0.0032 17.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG22892.1 - 0.0003 20.6 0.0 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 OAG22892.1 - 0.0012 17.6 0.0 0.01 14.6 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 OAG22892.1 - 0.027 14.8 0.4 3.2 8.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG22892.1 - 0.068 12.4 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ODC_AZ PF02100.17 OAG22893.1 - 7e-41 138.8 0.2 8.6e-41 138.5 0.2 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme FKBP_C PF00254.28 OAG22894.1 - 4.9e-32 110.1 0.0 1.1e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OAG22894.1 - 6e-29 100.7 2.8 6e-29 100.7 2.8 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain IMS PF00817.20 OAG22895.1 - 3.5e-40 137.5 0.0 7.7e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 OAG22895.1 - 4.7e-23 81.4 0.1 9.1e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 OAG22895.1 - 2.3e-16 58.6 14.8 7.4e-07 28.4 0.4 4.7 5 0 0 5 5 5 3 Ubiquitin binding region IMS_C PF11799.8 OAG22895.1 - 7.5e-12 46.0 0.0 4.7e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 OAG22895.1 - 1.3e-10 41.5 0.0 4.2e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG22895.1 - 1.3e-06 28.6 0.0 3.8e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG22895.1 - 0.00016 21.6 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain MgtE_N PF03448.17 OAG22895.1 - 0.02 15.5 3.1 25 5.5 0.2 3.8 4 0 0 4 4 4 0 MgtE intracellular N domain mCpol PF18182.1 OAG22895.1 - 0.037 14.4 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 minimal CRISPR polymerase domain IMS_HHH PF11798.8 OAG22895.1 - 0.079 13.3 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif KfrA_N PF11740.8 OAG22895.1 - 0.63 10.7 2.7 1 10.1 0.3 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EamA PF00892.20 OAG22900.1 - 1e-14 54.9 37.3 4.5e-09 36.6 15.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3671 PF12420.8 OAG22900.1 - 3.7 7.7 4.5 2.5 8.2 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function Acetyltransf_3 PF13302.7 OAG22901.1 - 7.7e-12 46.1 0.0 1e-11 45.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3328 PF11807.8 OAG22902.1 - 1.3 8.7 5.8 39 3.9 5.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) HAD_2 PF13419.6 OAG22903.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OAG22903.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Sugar_tr PF00083.24 OAG22904.1 - 5.1e-98 328.9 18.1 6.5e-98 328.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22904.1 - 2.4e-18 66.2 28.4 2.4e-18 66.2 28.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG22904.1 - 0.0017 16.8 3.3 0.0043 15.6 3.3 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Vma12 PF11712.8 OAG22904.1 - 0.28 11.3 1.5 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SPX PF03105.19 OAG22905.1 - 5.1 6.9 14.1 6.4 6.6 14.1 1.1 1 0 0 1 1 1 0 SPX domain SPX PF03105.19 OAG22907.1 - 0.075 12.9 9.6 0.093 12.6 9.6 1.1 1 0 0 1 1 1 0 SPX domain SHNi-TPR PF10516.9 OAG22908.1 - 2.1e-18 65.5 1.4 6.8e-16 57.4 0.3 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_10 PF13374.6 OAG22908.1 - 0.00012 21.8 2.0 0.052 13.4 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG22908.1 - 0.0015 18.8 14.4 0.0046 17.2 2.6 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG22908.1 - 0.0049 17.0 2.7 0.31 11.4 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG22908.1 - 0.005 16.6 2.6 0.68 9.9 0.4 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG22908.1 - 0.036 14.9 7.4 0.42 11.5 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG22908.1 - 0.094 12.9 0.5 0.094 12.9 0.5 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG22908.1 - 2 9.2 11.2 1.9 9.2 3.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 OAG22909.1 - 3e-48 164.0 0.1 4.5e-48 163.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B VTC PF09359.10 OAG22910.1 - 2.3e-98 329.0 0.5 2.3e-98 329.0 0.5 2.2 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 OAG22910.1 - 4e-12 46.4 4.8 8.7e-12 45.3 4.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 OAG22910.1 - 4.8e-10 39.9 24.4 4e-05 23.7 0.3 3.8 3 1 1 4 4 4 3 SPX domain Peptidase_M32 PF02074.15 OAG22910.1 - 0.0097 14.7 3.7 0.016 14.0 3.7 1.2 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF5446 PF17522.2 OAG22910.1 - 0.23 11.6 6.2 0.89 9.8 1.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) MscS_TM PF12794.7 OAG22910.1 - 2.2 7.0 4.5 0.36 9.7 0.5 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Patatin PF01734.22 OAG22912.1 - 3.5e-17 63.3 0.0 7e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase NDUF_B7 PF05676.13 OAG22913.1 - 0.0041 16.8 0.1 0.005 16.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) BaxI_1 PF12811.7 OAG22914.1 - 0.0063 16.1 0.8 0.0083 15.7 0.8 1.1 1 0 0 1 1 1 1 Bax inhibitor 1 like DDE_Tnp_ISL3 PF01610.17 OAG22914.1 - 0.043 13.5 0.8 0.061 13.0 0.8 1.2 1 0 0 1 1 1 0 Transposase AC_N PF16214.5 OAG22914.1 - 1.5 7.9 4.6 0.17 10.9 0.6 1.4 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Inositol_P PF00459.25 OAG22916.1 - 1.3e-40 139.7 0.7 5.4e-39 134.3 0.7 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Ecl1 PF12855.7 OAG22918.1 - 3.8e-17 64.0 24.8 4.7e-17 63.7 24.8 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 OAG22918.1 - 0.38 11.4 4.3 0.89 10.2 4.3 1.7 1 0 0 1 1 1 0 PLATZ transcription factor Aminotran_5 PF00266.19 OAG22922.1 - 6.8e-31 107.5 0.0 9.1e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG22922.1 - 0.0033 16.0 0.0 0.0049 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 OAG22922.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain SKG6 PF08693.10 OAG22923.1 - 0.0012 18.2 0.3 0.0021 17.4 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5385 PF17359.2 OAG22923.1 - 0.053 13.1 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4381 PF14316.6 OAG22923.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.15 OAG22923.1 - 0.079 12.9 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit AhpC-TSA PF00578.21 OAG22925.1 - 1.3e-23 83.3 0.0 1.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG22925.1 - 2e-16 60.1 0.0 3.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OAG22925.1 - 0.022 14.9 0.0 0.15 12.2 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme HSP9_HSP12 PF04119.12 OAG22925.1 - 0.064 13.7 1.6 0.064 13.7 1.6 2.5 3 0 0 3 3 3 0 Heat shock protein 9/12 Aa_trans PF01490.18 OAG22926.1 - 5.1e-32 111.1 28.3 8.1e-32 110.4 28.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-RING_2 PF13639.6 OAG22927.1 - 2e-09 37.6 4.7 2e-09 37.6 4.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG22927.1 - 1.9e-07 31.0 1.8 1.9e-07 31.0 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG22927.1 - 7.9e-05 22.9 3.7 7.9e-05 22.9 3.7 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 OAG22927.1 - 0.00017 21.5 2.2 0.00017 21.5 2.2 2.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 RINGv PF12906.7 OAG22927.1 - 0.00039 20.5 6.4 0.00086 19.4 6.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.6 OAG22927.1 - 0.00053 19.8 4.7 0.0012 18.6 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 OAG22927.1 - 0.00084 18.9 0.3 0.002 17.7 0.3 1.7 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 OAG22927.1 - 0.00097 19.0 7.2 0.0018 18.1 7.2 1.5 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 OAG22927.1 - 0.0017 18.5 12.0 0.0054 16.9 8.9 2.8 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.6 OAG22927.1 - 0.0034 17.3 6.1 0.0034 17.3 6.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG22927.1 - 0.0064 16.3 5.4 0.0064 16.3 5.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG22927.1 - 0.014 15.1 7.3 0.032 14.0 7.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 OAG22927.1 - 0.016 15.1 4.0 0.016 15.1 4.0 2.0 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG22927.1 - 0.018 15.1 2.5 0.041 13.9 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 OAG22927.1 - 0.17 12.0 6.7 0.051 13.7 2.6 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 OAG22927.1 - 0.28 11.0 2.9 0.74 9.6 2.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Baculo_IE-1 PF05290.11 OAG22927.1 - 0.31 11.0 3.9 0.65 9.9 3.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) C1_1 PF00130.22 OAG22927.1 - 0.39 10.6 6.9 0.16 11.9 2.7 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 OAG22927.1 - 0.86 9.3 7.5 0.21 11.2 4.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAG22927.1 - 2.6 8.0 9.2 14 5.7 5.2 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OAG22927.1 - 7.9 6.9 12.4 0.056 13.8 3.5 2.0 3 0 0 3 3 1 0 RING-like domain HNH_2 PF13391.6 OAG22931.1 - 6.6e-11 42.2 0.0 2.3e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease AIP3 PF03915.13 OAG22932.1 - 2.9e-155 517.4 14.9 2.9e-155 517.4 14.9 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 Sugar_tr PF00083.24 OAG22933.1 - 1.7e-102 343.6 20.9 3.6e-102 342.6 20.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG22933.1 - 3.7e-28 98.5 28.9 3.7e-28 98.5 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG22933.1 - 8.2e-06 24.5 3.2 8.2e-06 24.5 3.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 OAG22934.1 - 2.3e-37 126.3 25.9 3.5e-10 40.3 0.5 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG22934.1 - 2.1e-10 40.8 0.8 0.0055 17.0 0.1 5.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG22934.1 - 3.8e-06 26.1 0.4 0.7 8.8 0.0 4.2 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG22934.1 - 2.6e-05 23.1 5.9 2.2 6.8 0.1 4.8 3 2 1 5 5 5 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OAG22934.1 - 9.4e-05 21.5 0.1 9.4e-05 21.5 0.1 2.4 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 OAG22934.1 - 0.0032 15.9 0.0 0.0059 15.0 0.0 1.5 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 OAG22934.1 - 0.0064 15.3 0.1 1.5 7.5 0.1 2.6 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.11 OAG22934.1 - 0.013 15.2 0.5 3.5 7.3 0.1 3.1 1 1 1 2 2 2 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.14 OAG22934.1 - 0.029 13.4 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region FMN_dh PF01070.18 OAG22935.1 - 1.7e-107 359.5 0.0 2e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG22935.1 - 0.00032 19.8 0.3 0.00056 19.0 0.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG22935.1 - 0.0022 17.2 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG22935.1 - 0.0025 17.3 0.1 0.026 14.0 0.1 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 OAG22935.1 - 0.016 14.6 0.3 0.024 14.0 0.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 OAG22935.1 - 0.033 13.5 0.2 0.58 9.4 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PP2C PF00481.21 OAG22936.1 - 1.7e-82 277.0 0.0 2.5e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ACOX PF01756.19 OAG22937.1 - 1.4e-44 151.8 0.3 4.8e-44 150.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG22937.1 - 4e-29 101.7 0.3 8.9e-29 100.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG22937.1 - 1e-11 44.8 0.0 3.4e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG22937.1 - 8.7e-06 26.0 0.0 0.0099 16.1 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG22937.1 - 0.18 12.5 0.0 0.4 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Alba PF01918.21 OAG22940.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Alba FAD_binding_4 PF01565.23 OAG22941.1 - 9e-21 74.1 6.0 1.5e-20 73.3 6.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG22941.1 - 2.7e-06 27.4 0.1 5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like NPCC PF08058.11 OAG22941.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore complex component Aminotran_3 PF00202.21 OAG22942.1 - 2.2e-39 135.3 0.0 6.3e-16 58.0 0.0 3.6 3 1 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 OAG22942.1 - 5.8e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG22942.1 - 0.0011 19.3 0.1 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase CbiA PF01656.23 OAG22942.1 - 0.038 14.1 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.21 OAG22943.1 - 2.1e-38 132.5 0.0 2.6e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG22943.1 - 0.017 13.7 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.13 OAG22944.1 - 1.4e-22 79.6 0.0 3.3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAG22944.1 - 1e-14 55.3 0.2 1.6e-13 51.4 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Aconitase PF00330.20 OAG22945.1 - 7.2e-132 440.6 0.0 9.8e-132 440.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG22945.1 - 1.5e-34 119.1 0.0 2.6e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 OAG22945.1 - 0.053 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Alg14 PF08660.11 OAG22946.1 - 0.0096 15.9 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4395 PF14340.6 OAG22946.1 - 0.036 14.4 2.9 0.062 13.6 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) DHHC PF01529.20 OAG22946.1 - 0.1 12.7 0.8 17 5.5 0.0 2.4 1 1 0 2 2 2 0 DHHC palmitoyltransferase DUF2721 PF11026.8 OAG22946.1 - 0.45 10.4 6.4 0.062 13.2 1.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Abhydrolase_6 PF12697.7 OAG22947.1 - 4.4e-05 24.2 0.0 7.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG22947.1 - 0.0001 22.1 0.1 0.0026 17.5 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 OAG22947.1 - 0.004 16.5 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 OAG22947.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 OAG22947.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OAG22947.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold Borrelia_P83 PF05262.11 OAG22947.1 - 0.37 9.2 29.4 0.49 8.8 29.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Senescence PF06911.12 OAG22947.1 - 0.44 10.8 3.0 1.3 9.3 3.0 1.7 1 0 0 1 1 1 0 Senescence-associated protein DUF2151 PF10221.9 OAG22947.1 - 3.5 6.1 16.0 5.8 5.4 16.0 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Syndecan PF01034.20 OAG22948.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain LOR PF04525.12 OAG22949.1 - 8.2e-23 81.0 0.0 1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related SAM_PNT PF02198.16 OAG22949.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.32 OAG22950.1 - 1.7e-25 88.7 11.7 9.6e-06 26.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 OAG22950.1 - 8.8e-10 38.3 0.2 1.9e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OAG22950.1 - 1.5e-07 30.4 0.2 0.0078 14.9 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.33 OAG22950.1 - 2.7e-06 27.1 0.1 5.4e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 OAG22950.1 - 0.0061 16.2 0.7 0.025 14.1 0.7 2.0 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 OAG22950.1 - 0.011 16.2 0.3 2.4 8.8 0.0 3.4 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 OAG22950.1 - 0.039 13.9 0.0 11 6.2 0.1 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat WD40_like PF17005.5 OAG22950.1 - 0.086 12.1 0.3 14 4.9 0.0 3.6 2 1 3 5 5 5 0 WD40-like domain Amelogenin PF02948.15 OAG22950.1 - 0.16 12.6 5.1 0.65 10.6 5.4 1.9 2 0 0 2 2 2 0 Amelogenin KIX_2 PF16987.5 OAG22952.1 - 5.5e-08 32.7 0.4 5.5e-08 32.7 0.4 5.0 4 0 0 4 4 4 2 KIX domain COX6C PF02937.15 OAG22954.1 - 0.037 14.2 0.0 0.042 14.0 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc TAF8_C PF10406.9 OAG22955.1 - 1.7e-20 73.3 0.5 1.7e-20 73.3 0.5 2.4 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 OAG22955.1 - 2.3e-06 27.5 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mitochondr_Som1 PF11093.8 OAG22956.1 - 4.1e-21 74.8 0.0 4.6e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DAPG_hydrolase PF18089.1 OAG22956.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain MRP-L20 PF12824.7 OAG22958.1 - 4.6e-55 186.3 4.7 5.4e-55 186.0 4.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF1179 PF06678.11 OAG22958.1 - 0.026 14.5 3.0 0.13 12.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Neugrin PF06413.11 OAG22958.1 - 0.068 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Neugrin Peptidase_M20 PF01546.28 OAG22959.1 - 8.9e-34 117.0 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG22959.1 - 9.6e-13 48.0 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_transf_8 PF01501.20 OAG22960.1 - 6e-24 85.0 0.8 4.2e-23 82.2 0.8 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAG22960.1 - 0.0053 16.2 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Prok-E2_E PF14462.6 OAG22960.1 - 0.038 13.8 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family E Nucleotid_trans PF03407.16 OAG22960.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase FAD_binding_7 PF03441.14 OAG22961.1 - 6.7e-74 247.7 0.4 9.8e-74 247.2 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG22961.1 - 2.1e-37 128.6 0.0 6.5e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Dynactin_p62 PF05502.13 OAG22962.1 - 3.2e-199 662.7 0.2 3.9e-199 662.4 0.2 1.0 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.9 OAG22962.1 - 4.5 6.8 7.7 13 5.4 3.4 3.1 2 1 0 2 2 2 0 Mu-like prophage protein Com Methyltransf_23 PF13489.6 OAG22963.1 - 1.4e-09 38.0 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG22963.1 - 1.5e-09 38.4 0.0 2.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG22963.1 - 1.3e-06 29.1 0.0 2.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG22963.1 - 1.4e-05 25.7 0.0 3.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG22963.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG22963.1 - 0.0026 17.2 0.0 0.0052 16.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF1793 PF08760.11 OAG22965.1 - 1.9e-70 236.6 0.3 4e-70 235.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAG22965.1 - 2.3e-62 209.7 0.4 2.7e-49 167.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAG22965.1 - 1e-38 133.4 0.2 1.7e-38 132.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAG22965.1 - 3.9e-05 23.1 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) CFEM PF05730.11 OAG22968.1 - 4.4e-11 42.7 5.4 8.1e-11 41.9 5.4 1.5 1 0 0 1 1 1 1 CFEM domain DUF1295 PF06966.12 OAG22970.1 - 2.5e-33 115.6 6.6 3.1e-33 115.2 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAG22970.1 - 0.1 13.0 1.3 0.57 10.6 0.0 2.6 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family BALF1 PF06861.11 OAG22970.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 BALF1 protein Topoisom_bac PF01131.20 OAG22971.1 - 8.9e-103 344.5 0.0 8.8e-96 321.4 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 OAG22971.1 - 7.4e-19 67.9 0.0 2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.9 OAG22972.1 - 6.1e-29 99.9 0.6 1.1e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 Putative Sin3 binding protein PLDc_2 PF13091.6 OAG22973.1 - 4.9e-24 84.7 0.0 2.4e-16 59.8 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAG22973.1 - 0.001 19.2 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif ECR1_N PF14382.6 OAG22974.1 - 2.3e-15 56.1 0.5 5.3e-15 54.9 0.5 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OAG22974.1 - 0.001 19.4 0.1 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 OAG22974.1 - 0.046 13.7 0.2 0.099 12.6 0.2 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain EXOSC1 PF10447.9 OAG22974.1 - 0.051 14.2 0.1 1.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 TMEM234 PF10639.9 OAG22976.1 - 1.4e-41 141.2 1.1 1.6e-41 141.0 1.1 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OAG22976.1 - 8.5e-05 22.8 11.1 0.1 12.8 7.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family DUF5493 PF17597.2 OAG22976.1 - 0.011 16.0 2.7 2.1 8.7 2.7 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5493) PhyH PF05721.13 OAG22977.1 - 5.8e-54 183.5 0.0 7.9e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ketoacyl-synt PF00109.26 OAG22978.1 - 2.6e-70 236.9 0.0 4.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG22978.1 - 3e-60 203.2 3.5 1e-58 198.2 0.2 3.7 4 0 0 4 4 4 1 KR domain PS-DH PF14765.6 OAG22978.1 - 4.6e-50 170.5 0.1 1e-49 169.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG22978.1 - 2.5e-45 155.3 0.3 4.4e-45 154.6 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG22978.1 - 5.1e-35 120.0 0.0 1.8e-34 118.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG22978.1 - 2e-10 41.1 0.0 1.4e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG22978.1 - 9.2e-10 38.3 0.0 6e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 OAG22978.1 - 1.1e-05 25.3 0.1 2.5e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 OAG22978.1 - 2.7e-05 23.8 0.0 6.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 OAG22978.1 - 3.2e-05 24.2 0.1 8.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 OAG22978.1 - 0.0019 18.2 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 OAG22978.1 - 0.0019 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 OAG22978.1 - 0.012 16.7 0.0 0.039 15.0 0.0 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HAD PF12710.7 OAG22979.1 - 9.3e-19 68.6 0.0 1.5e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG22979.1 - 1.6e-14 54.7 0.2 3.2e-14 53.7 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG22979.1 - 1.8e-08 34.4 0.3 9.7e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG22979.1 - 0.00033 20.8 0.1 0.021 14.9 0.1 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG22979.1 - 0.0015 18.0 0.0 0.034 13.5 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase adh_short PF00106.25 OAG22980.1 - 2.8e-34 118.3 0.0 7.5e-33 113.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG22980.1 - 6.1e-26 91.4 0.0 2.6e-24 86.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG22980.1 - 1.6e-07 31.4 0.1 5.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG22980.1 - 0.0084 15.6 0.1 0.038 13.5 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SPC12 PF06645.13 OAG22980.1 - 0.15 12.2 0.2 11 6.2 0.3 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GDP_Man_Dehyd PF16363.5 OAG22980.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_28 PF03033.20 OAG22981.1 - 1.6e-17 63.9 0.0 5.7e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG22981.1 - 1.7e-07 30.5 0.0 2.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG22981.1 - 0.057 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain FAD_binding_3 PF01494.19 OAG22982.1 - 1.9e-15 57.0 0.0 3.7e-15 56.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG22982.1 - 5e-07 29.6 0.0 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG22982.1 - 6.3e-07 28.9 0.0 0.00069 18.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG22982.1 - 0.00065 20.2 0.0 0.17 12.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG22982.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 OAG22983.1 - 1.9e-10 40.3 0.0 3.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG22983.1 - 3.1e-10 40.0 10.6 6.1e-10 39.1 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4149 PF13664.6 OAG22985.1 - 1.4e-27 96.0 1.7 1.4e-27 96.0 1.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) Methyltransf_16 PF10294.9 OAG22986.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OAG22987.1 - 6.8e-20 71.4 0.0 9.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG22987.1 - 7.9e-09 36.2 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG22987.1 - 5.8e-07 30.1 0.0 8.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG22987.1 - 3.6e-06 26.9 0.0 8.6e-06 25.7 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG22987.1 - 0.00018 21.6 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG22987.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OAG22987.1 - 0.0011 19.6 0.0 0.0018 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG22987.1 - 0.0088 15.4 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 OAG22987.1 - 0.039 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 OAG22987.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OAG22987.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.13 OAG22987.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase GTP_EFTU PF00009.27 OAG22988.1 - 2.6e-55 187.0 0.0 4.5e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG22988.1 - 7.1e-42 142.2 0.0 1.7e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG22988.1 - 1.1e-13 51.4 2.7 1.1e-13 51.4 2.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG22988.1 - 0.00053 20.0 0.2 0.013 15.6 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5102 PF17104.5 OAG22989.1 - 0.017 15.2 13.1 0.26 11.3 0.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) HofP PF10748.9 OAG22989.1 - 0.025 14.2 0.0 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 DNA utilization proteins HofP Pkinase PF00069.25 OAG22990.1 - 6.3e-57 192.9 0.1 8.7e-57 192.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG22990.1 - 7.4e-21 74.6 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG22990.1 - 5e-07 29.3 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG22990.1 - 4.9e-05 22.4 0.1 7.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAG22990.1 - 0.00094 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAG22990.1 - 0.0036 17.3 0.3 0.27 11.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG22990.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Homeobox_KN PF05920.11 OAG22991.1 - 9.2e-14 51.1 1.3 2.2e-13 49.9 1.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG22991.1 - 5.1e-10 39.0 0.6 9.4e-10 38.2 0.6 1.5 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 OAG22991.1 - 0.05 13.5 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-C2H2 PF00096.26 OAG22991.1 - 0.52 10.9 0.0 0.52 10.9 0.0 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 OAG22991.1 - 2.7 8.4 6.5 1.1 9.6 0.8 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.21 OAG22991.1 - 4.5 8.0 9.1 1.2 9.8 0.1 3.6 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain zf-Sec23_Sec24 PF04810.15 OAG22991.1 - 7.9 6.6 15.3 1.2 9.3 0.4 4.9 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger Peptidase_M14 PF00246.24 OAG22992.1 - 8.4e-65 219.4 0.1 1.1e-64 219.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Helicase_C_3 PF13625.6 OAG22992.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NUDIX PF00293.28 OAG22993.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ferric_reduct PF01794.19 OAG22994.1 - 7e-25 87.6 7.3 7e-25 87.6 7.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG22994.1 - 1.5e-17 64.1 0.0 6.5e-11 42.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG22994.1 - 3e-12 46.6 0.0 4.8e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain RabGAP-TBC PF00566.18 OAG22996.1 - 3e-31 108.7 0.2 5.1e-31 108.0 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Med31 PF05669.12 OAG22997.1 - 2.5e-33 113.9 0.5 3e-33 113.7 0.5 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 OAG22998.1 - 2.2e-44 151.6 3.3 9.9e-43 146.2 0.3 2.5 2 0 0 2 2 2 2 Pal1 cell morphology protein Rad51 PF08423.11 OAG22999.1 - 1.5e-10 40.8 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 OAG22999.1 - 9e-06 25.2 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 OAG22999.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein A_deamin PF02137.18 OAG23000.1 - 4.3e-27 95.4 0.0 4.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NT-C2 PF10358.9 OAG23001.1 - 9.5e-37 125.9 0.0 1.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 OAG23002.1 - 7.6e-38 130.6 0.2 3.1e-37 128.6 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Dimerisation PF08100.11 OAG23002.1 - 0.038 14.0 0.4 1 9.5 0.0 2.7 2 0 0 2 2 2 0 Dimerisation domain Exotox-A_target PF09102.10 OAG23002.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Exotoxin A, targeting Whi5 PF08528.11 OAG23003.1 - 0.0025 17.4 1.6 0.0056 16.3 1.6 1.6 1 0 0 1 1 1 1 Whi5 like Cellulase PF00150.18 OAG23004.1 - 3.5e-10 39.8 0.1 5.5e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Bacteriocin_IIi PF11758.8 OAG23004.1 - 0.048 13.5 0.3 0.18 11.7 0.3 1.9 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Spore_YpjB PF09577.10 OAG23005.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) SDA1 PF05285.12 OAG23006.1 - 7.8 5.8 19.5 0.38 10.1 13.3 1.7 2 0 0 2 2 2 0 SDA1 adh_short_C2 PF13561.6 OAG23011.1 - 8e-45 153.2 0.0 9.6e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG23011.1 - 7.6e-35 120.1 0.0 9.6e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG23011.1 - 1.3e-06 28.5 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG23011.1 - 0.00012 21.7 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG23011.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG23011.1 - 0.04 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 OAG23011.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 OAG23011.1 - 0.084 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cu-oxidase_3 PF07732.15 OAG23012.1 - 3e-35 120.8 0.8 3e-35 120.8 0.8 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG23012.1 - 1.3e-31 109.9 0.0 8.3e-29 100.7 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG23012.1 - 3.8e-29 101.2 11.0 1.4e-26 92.9 3.4 4.1 3 1 0 3 3 3 2 Multicopper oxidase Glyco_hydro_61 PF03443.14 OAG23013.1 - 1.1e-53 182.2 0.0 2.5e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG23013.1 - 5.1e-08 32.7 9.5 1.3e-07 31.5 9.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain peroxidase PF00141.23 OAG23014.1 - 2.7e-32 112.3 0.7 4.9e-32 111.5 0.7 1.4 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG23014.1 - 5e-06 26.4 0.0 9.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region F-box PF00646.33 OAG23015.1 - 0.062 13.2 1.1 0.31 11.0 1.1 2.3 1 0 0 1 1 1 0 F-box domain B56 PF01603.20 OAG23015.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4588 PF15251.6 OAG23016.1 - 0.00013 21.8 2.7 0.0003 20.6 2.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Adap_comp_sub PF00928.21 OAG23017.1 - 7.5e-56 189.4 0.0 9.3e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG23017.1 - 4.1e-05 23.6 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PKcGMP_CC PF16808.5 OAG23018.1 - 0.021 14.7 14.4 0.74 9.7 1.8 4.2 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 OAG23018.1 - 0.54 10.6 10.2 0.51 10.7 3.3 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) XLF PF09302.11 OAG23018.1 - 0.76 9.9 7.8 1.4 9.1 0.6 2.6 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF2570 PF10828.8 OAG23018.1 - 0.98 9.3 6.0 0.29 11.0 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) SlyX PF04102.12 OAG23018.1 - 0.99 10.1 12.8 0.4 11.3 3.2 3.8 2 1 1 3 3 3 0 SlyX FAM76 PF16046.5 OAG23018.1 - 1.9 7.8 5.0 3.8 6.8 5.0 1.5 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 OAG23018.1 - 7.2 7.0 20.1 2e+02 2.3 0.0 3.1 2 1 0 2 2 2 0 Fez1 DUF4267 PF14087.6 OAG23019.1 - 6.8e-23 80.9 0.2 8.4e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) NMT1 PF09084.11 OAG23020.1 - 2.6e-76 256.3 0.0 3.5e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 OAG23020.1 - 5.1e-06 26.4 0.0 0.072 12.8 0.0 2.9 3 1 1 4 4 4 2 NMT1-like family MltA PF03562.17 OAG23020.1 - 0.1 12.4 0.2 17 5.1 0.0 2.6 3 0 0 3 3 3 0 MltA specific insert domain MdcG PF10620.9 OAG23020.1 - 0.22 11.3 0.1 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG RRM_1 PF00076.22 OAG23021.1 - 1.9e-46 155.8 0.1 4.1e-15 55.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG23021.1 - 1.1e-29 102.1 0.0 1.8e-24 85.4 0.0 3.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG23021.1 - 5.7e-07 29.4 0.0 0.23 11.5 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAG23021.1 - 0.0012 19.0 0.0 0.027 14.6 0.0 3.3 4 0 0 4 4 4 1 RNA recognition motif Lsm_interact PF05391.11 OAG23021.1 - 0.034 13.6 0.1 0.077 12.5 0.1 1.6 1 0 0 1 1 1 0 Lsm interaction motif Ribosomal_L22 PF00237.19 OAG23022.1 - 6.3e-22 77.8 0.1 1.2e-20 73.6 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e HTH_8 PF02954.19 OAG23022.1 - 0.0013 18.5 1.1 0.0013 18.5 1.1 2.1 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family betaPIX_CC PF16523.5 OAG23022.1 - 2.8 7.8 10.2 0.062 13.1 2.3 2.3 3 0 0 3 3 3 0 betaPIX coiled coil UTP15_C PF09384.10 OAG23023.1 - 3e-47 160.0 0.3 5.3e-47 159.2 0.3 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAG23023.1 - 1.1e-17 64.0 2.1 0.0019 19.0 0.3 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23023.1 - 4.9e-08 33.2 0.6 0.02 15.2 0.1 4.5 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PAS_2 PF08446.11 OAG23023.1 - 0.1 13.3 0.2 2.2 9.0 0.1 2.4 2 0 0 2 2 2 0 PAS fold Homeodomain PF00046.29 OAG23024.1 - 1.6e-11 43.9 0.1 6.3e-11 42.0 0.1 2.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG23024.1 - 2.2e-06 27.5 0.2 8.9e-06 25.5 0.2 2.1 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.6 OAG23024.1 - 0.0092 16.7 1.0 0.0092 16.7 1.0 7.4 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG23024.1 - 0.018 15.3 14.0 0.047 14.0 0.7 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG23024.1 - 0.039 14.4 0.8 0.039 14.4 0.8 5.8 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-FCS PF06467.14 OAG23024.1 - 0.34 10.9 4.1 3.3 7.7 0.9 3.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF1390 PF07150.11 OAG23024.1 - 0.42 10.3 5.8 0.33 10.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) zf-C2H2_6 PF13912.6 OAG23024.1 - 0.81 9.8 6.1 1.3 9.2 1.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Lipase_GDSL_2 PF13472.6 OAG23025.1 - 1.3e-05 25.7 0.0 2.7e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1631 PF07793.11 OAG23025.1 - 0.39 9.1 2.9 0.19 10.1 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) TFIIS_C PF01096.18 OAG23026.1 - 2.5e-19 68.8 5.5 2.5e-19 68.8 5.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAG23026.1 - 0.00013 21.7 7.9 0.016 15.1 0.0 3.5 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Acetone_carb_G PF08882.11 OAG23026.1 - 0.031 14.4 3.6 0.05 13.7 0.1 2.3 1 1 0 2 2 2 0 Acetone carboxylase gamma subunit zf-H2C2_2 PF13465.6 OAG23026.1 - 0.15 12.6 11.4 1.5 9.4 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain C1_4 PF07975.12 OAG23026.1 - 0.35 11.1 8.5 5.4 7.3 0.8 3.4 2 2 1 3 3 3 0 TFIIH C1-like domain PhnA_Zn_Ribbon PF08274.12 OAG23026.1 - 0.55 10.2 5.5 11 6.1 1.0 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-Mss51 PF13824.6 OAG23026.1 - 1.6 8.9 6.6 1.8 8.8 0.5 2.7 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ank_5 PF13857.6 OAG23027.1 - 1.1e-09 38.4 0.8 2e-05 24.8 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG23027.1 - 3.1e-09 36.3 0.1 0.002 18.5 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAG23027.1 - 1.5e-07 31.9 0.0 7.4e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG23027.1 - 1.9e-07 31.2 0.0 0.036 14.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAG23027.1 - 2.9e-07 30.9 0.0 1.7e-05 25.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Nexin_C PF08628.12 OAG23027.1 - 0.2 12.2 0.0 0.44 11.2 0.0 1.5 2 0 0 2 2 2 0 Sorting nexin C terminal SF3b10 PF07189.11 OAG23028.1 - 5.5e-35 119.3 0.0 6.1e-35 119.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Vinculin PF01044.19 OAG23029.1 - 0.005 15.1 0.0 0.0058 14.9 0.0 1.0 1 0 0 1 1 1 1 Vinculin family Co_AT_N PF12557.8 OAG23029.1 - 1 9.4 8.0 0.14 12.1 4.0 1.7 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Abhydrolase_6 PF12697.7 OAG23030.1 - 2.2e-12 48.0 0.7 5.2e-11 43.6 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG23030.1 - 1.1e-09 38.3 0.0 0.00064 19.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG23030.1 - 0.041 13.1 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fungal_trans PF04082.18 OAG23031.1 - 1.6e-27 96.2 0.4 8.2e-27 93.9 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23031.1 - 0.00015 21.8 16.5 0.00029 20.9 16.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 OAG23032.1 - 1.5e-42 146.1 0.0 2.1e-41 142.3 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III Spidroin_N PF16763.5 OAG23032.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term FSH1 PF03959.13 OAG23034.1 - 6.8e-14 52.0 0.0 9.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG23034.1 - 0.025 14.4 0.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase STALD PF18185.1 OAG23034.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family DUF3074 PF11274.8 OAG23035.1 - 1.8e-60 204.1 1.0 1.6e-59 201.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 OAG23035.1 - 0.00067 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 START domain Exonuc_VII_L PF02601.15 OAG23035.1 - 1.8 8.1 18.2 2.6 7.5 18.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 OAG23035.1 - 2.3 8.3 37.8 4.5 7.3 37.8 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cupin_8 PF13621.6 OAG23035.1 - 7.2 6.2 12.2 4.6 6.9 10.4 1.5 2 0 0 2 2 2 0 Cupin-like domain DUF4407 PF14362.6 OAG23035.1 - 7.6 5.8 21.0 13 5.1 21.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpL_GvpF PF06386.11 OAG23035.1 - 8.3 6.3 16.6 18 5.1 16.6 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MBOAT PF03062.19 OAG23036.1 - 1.6e-33 116.5 21.7 5.4e-33 114.8 20.9 1.9 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAG23036.1 - 0.0059 16.9 2.1 0.016 15.5 2.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Adaptin_N PF01602.20 OAG23037.1 - 5.8e-144 480.5 0.6 6.9e-144 480.3 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAG23037.1 - 1.1e-24 86.9 0.0 3e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG23037.1 - 8.7e-08 32.4 6.8 0.00012 22.1 0.1 4.1 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 OAG23037.1 - 0.00027 20.6 0.1 0.0023 17.5 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 OAG23037.1 - 0.00042 20.7 4.0 0.48 10.8 0.0 4.2 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 OAG23037.1 - 0.0073 16.5 1.5 20 5.8 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 OAG23037.1 - 0.0087 15.6 0.1 0.2 11.2 0.0 2.5 2 1 0 2 2 2 1 CLASP N terminal Arm PF00514.23 OAG23037.1 - 0.02 14.9 0.0 62 3.8 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Glyco_hydro_47 PF01532.20 OAG23038.1 - 2.5e-131 438.8 0.0 2.8e-131 438.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Efg1 PF10153.9 OAG23039.1 - 8.1e-31 106.7 10.5 8.1e-31 106.7 10.5 2.3 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Pox_A_type_inc PF04508.12 OAG23039.1 - 5.7 7.0 8.4 2.2 8.3 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat zinc_ribbon_16 PF17034.5 OAG23040.1 - 7.3e-20 71.4 5.9 2.3e-19 69.8 5.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 OAG23040.1 - 0.0006 19.4 9.8 0.0018 17.8 9.8 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 OAG23040.1 - 0.062 13.6 6.5 0.054 13.8 4.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain LRR_6 PF13516.6 OAG23041.1 - 2.4e-17 61.4 20.5 0.02 14.9 0.1 12.5 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 OAG23041.1 - 5e-16 58.5 6.7 0.048 14.1 0.0 6.9 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG23041.1 - 2.1e-08 33.9 0.1 9e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like DUF1699 PF08004.11 OAG23041.1 - 0.003 17.2 0.1 0.63 9.7 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1699) F-box PF00646.33 OAG23041.1 - 0.0049 16.7 0.7 0.033 14.1 0.1 2.8 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.24 OAG23041.1 - 0.02 15.0 0.4 4.4 7.5 0.0 3.7 2 1 1 3 3 3 0 Receptor L domain SAM_Ste50p PF09235.10 OAG23041.1 - 0.66 10.3 19.9 34 4.8 0.4 8.1 4 3 3 8 8 8 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 OAG23041.1 - 2.9 8.8 22.1 86 4.3 0.0 8.1 9 1 0 9 9 9 0 Leucine Rich Repeat Pkinase PF00069.25 OAG23042.1 - 4.4e-40 137.7 0.0 8.1e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23042.1 - 9.6e-31 107.0 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG23042.1 - 0.027 14.4 0.4 8.2 6.3 0.0 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG23042.1 - 0.036 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OAG23042.1 - 0.036 12.8 0.4 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_L7Ae PF01248.26 OAG23043.1 - 2.6e-26 91.2 0.8 3.4e-26 90.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAG23043.1 - 0.099 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ribosomal_L18_c PF14204.6 OAG23044.1 - 0.46 11.5 3.1 0.95 10.4 2.3 2.0 1 1 0 1 1 1 0 Ribosomal L18 C-terminal region Ferric_reduct PF01794.19 OAG23045.1 - 2.8e-20 72.7 8.2 2.8e-20 72.7 8.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG23045.1 - 1.4e-12 48.0 0.0 1e-11 45.2 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG23045.1 - 3e-08 33.7 0.0 6.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain IU_nuc_hydro PF01156.19 OAG23046.1 - 2.5e-71 240.7 0.0 3e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_10 PF00331.20 OAG23047.1 - 2.7e-92 309.3 0.4 3.1e-92 309.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-C2H2 PF00096.26 OAG23048.1 - 1.1e-05 25.6 15.8 3.2e-05 24.2 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG23048.1 - 1.6e-05 25.1 6.4 2.5e-05 24.5 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG23048.1 - 0.0001 22.8 1.7 0.0001 22.8 1.7 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG23048.1 - 0.0032 17.4 1.3 0.0077 16.2 1.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG23048.1 - 0.0036 17.6 0.7 0.0036 17.6 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAG23048.1 - 0.015 15.6 1.2 0.034 14.4 1.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 OAG23048.1 - 0.022 15.4 7.7 0.55 10.9 0.6 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 OAG23048.1 - 0.89 10.3 6.0 0.32 11.7 2.5 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger DUF3602 PF12223.8 OAG23049.1 - 1.6e-11 44.6 10.6 2.5e-05 24.8 4.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 OAG23049.1 - 0.0058 16.2 4.6 0.041 13.5 0.0 2.9 1 1 2 3 3 3 1 GTP1/OBG V-SNARE_C PF12352.8 OAG23050.1 - 0.015 15.6 2.7 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus BAG PF02179.16 OAG23051.1 - 6.3e-20 71.4 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 BAG domain TFIIF_alpha PF05793.12 OAG23051.1 - 0.00068 18.4 4.4 0.00097 17.8 4.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 OAG23051.1 - 0.05 11.7 4.9 0.065 11.3 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GFO_IDH_MocA PF01408.22 OAG23052.1 - 1.9e-10 41.6 0.6 8.9e-10 39.4 0.4 2.3 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 OAG23053.1 - 6.6e-35 120.2 0.1 8.1e-35 119.9 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AcetylCoA_hyd_C PF13336.6 OAG23053.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Fungal_trans PF04082.18 OAG23054.1 - 2e-26 92.6 0.0 4.3e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23054.1 - 2.8e-09 36.9 11.2 6.4e-09 35.8 11.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG23054.1 - 0.0065 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIF PF05092.12 OAG23054.1 - 0.14 10.9 3.0 0.21 10.2 3.0 1.1 1 0 0 1 1 1 0 Per os infectivity GST_N_3 PF13417.6 OAG23055.1 - 3.9e-14 52.8 0.0 7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG23055.1 - 7.5e-13 48.6 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG23055.1 - 3e-12 46.7 0.0 5.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG23055.1 - 2e-10 40.7 0.0 3.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG23055.1 - 1.2e-09 38.3 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG23055.1 - 2.4e-07 30.7 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MAGE_N PF12440.8 OAG23056.1 - 2.7 8.7 5.0 6 7.6 5.0 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Myotub-related PF06602.14 OAG23057.1 - 1.3e-146 488.1 0.0 1.6e-146 487.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF3993 PF13158.6 OAG23058.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) MFS_1 PF07690.16 OAG23061.1 - 1.9e-37 129.1 21.4 1.9e-37 129.1 21.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Nuc_sug_transp PF04142.15 OAG23061.1 - 1.5e-09 37.5 0.4 5.3e-09 35.7 0.4 1.9 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OAG23061.1 - 2.2e-07 31.1 23.4 7.8e-05 22.9 1.6 5.5 4 1 1 5 5 5 2 EamA-like transporter family UAA PF08449.11 OAG23061.1 - 9.3e-05 21.8 10.8 9.3e-05 21.8 10.8 2.9 3 0 0 3 3 3 1 UAA transporter family TPT PF03151.16 OAG23061.1 - 0.00065 19.1 9.1 0.0012 18.3 0.1 2.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family Ribosomal_S3_C PF00189.20 OAG23062.1 - 8.6e-25 87.1 0.1 4.7e-24 84.7 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAG23062.1 - 6.4e-12 45.1 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 OAG23062.1 - 0.08 12.7 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 OAG23062.1 - 0.11 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Glyco_hydro_53 PF07745.13 OAG23063.1 - 4.4e-109 364.6 0.5 5e-109 364.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sdh5 PF03937.16 OAG23064.1 - 5.7e-24 83.9 0.1 1.3e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase adh_short PF00106.25 OAG23065.1 - 2.2e-34 118.7 0.8 3.5e-34 118.0 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23065.1 - 7.2e-28 97.7 0.4 1e-27 97.2 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23065.1 - 7.8e-08 32.4 0.6 1.1e-07 31.9 0.6 1.2 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 OAG23065.1 - 0.042 14.5 0.0 0.09 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Nucleotid_trans PF03407.16 OAG23067.1 - 2.8e-09 37.2 0.1 6.1e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 OAG23067.1 - 2e-06 27.7 3.5 7.2e-06 25.9 3.5 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF2947 PF11163.8 OAG23067.1 - 0.029 14.2 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) mRNA_decap_C PF16741.5 OAG23067.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Zn_clus PF00172.18 OAG23068.1 - 1.7e-09 37.7 10.0 3e-09 36.8 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG23068.1 - 1.6e-05 24.1 0.5 2.7e-05 23.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PALP PF00291.25 OAG23069.1 - 2.3e-55 188.1 1.4 1.7e-54 185.3 1.4 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S10 PF00450.22 OAG23070.1 - 5.7e-81 273.1 0.2 7.1e-81 272.7 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pro-kuma_activ PF09286.11 OAG23071.1 - 5.9e-38 130.4 0.0 1.1e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG23071.1 - 0.0002 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family HAD_2 PF13419.6 OAG23072.1 - 1.1e-14 55.0 0.0 3e-14 53.5 0.0 1.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG23072.1 - 1.1e-10 42.2 0.1 3.4e-07 30.8 0.0 2.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG23072.1 - 1.4e-06 28.3 0.3 4.3e-06 26.7 0.3 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 OAG23072.1 - 0.0015 19.0 0.0 0.021 15.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OAG23072.1 - 0.029 14.0 0.0 2.8 7.5 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Glyco_hydro_18 PF00704.28 OAG23073.1 - 1.5e-72 245.0 3.9 1.9e-72 244.7 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_28 PF00295.17 OAG23076.1 - 7.7e-126 419.6 27.4 8.7e-126 419.4 27.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 LVIVD PF08309.11 OAG23077.1 - 0.0097 15.2 0.8 1.8 7.9 0.0 3.1 2 0 0 2 2 2 2 LVIVD repeat Fungal_trans PF04082.18 OAG23078.1 - 4.7e-29 101.2 0.0 8.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23078.1 - 2.7e-11 43.4 12.6 4.5e-11 42.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L13 PF00572.18 OAG23079.1 - 2.6e-09 37.4 0.1 2.7e-07 30.9 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 AMP-binding PF00501.28 OAG23080.1 - 5.7e-74 249.2 0.1 7.2e-74 248.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG23080.1 - 1.2e-19 71.0 0.0 2.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UAA PF08449.11 OAG23082.1 - 3e-45 154.7 9.9 4.1e-45 154.3 9.9 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG23082.1 - 3.9e-05 23.8 26.2 0.0015 18.7 11.1 3.4 2 2 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG23082.1 - 4.9e-05 22.7 1.5 0.0033 16.6 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter UPF0060 PF02694.15 OAG23082.1 - 0.056 13.7 0.3 0.056 13.7 0.3 2.7 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family KH_1 PF00013.29 OAG23084.1 - 3.6e-41 138.8 9.9 1.4e-17 63.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG23084.1 - 2.7e-10 39.9 11.1 0.0033 17.2 1.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 OAG23084.1 - 1.8e-08 34.2 5.7 0.053 13.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG23084.1 - 0.00013 22.0 6.7 0.19 11.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain ADH_N PF08240.12 OAG23085.1 - 7.3e-30 103.1 1.5 7.3e-30 103.1 1.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG23085.1 - 4.3e-16 59.1 0.0 8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG23085.1 - 0.00031 20.3 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 OAG23085.1 - 0.002 18.0 0.6 0.002 18.0 0.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.14 OAG23086.1 - 5.4e-16 58.7 0.5 7.1e-16 58.3 0.5 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAG23086.1 - 0.0012 19.1 0.7 0.0019 18.4 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I Zn_ribbon_SprT PF17283.2 OAG23086.1 - 0.025 14.5 1.6 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GFA PF04828.14 OAG23086.1 - 0.077 13.3 1.1 11 6.5 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-RRPl_C4 PF17026.5 OAG23086.1 - 0.099 12.8 2.4 0.36 11.0 1.6 2.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Evr1_Alr PF04777.13 OAG23086.1 - 0.16 12.5 0.7 2.4 8.7 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family TPR_1 PF00515.28 OAG23088.1 - 5.3e-44 146.3 15.9 7.8e-08 31.8 0.1 8.3 8 1 1 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAG23088.1 - 1.2e-37 124.9 14.4 1.7e-06 27.7 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 OAG23088.1 - 6.3e-30 102.6 16.6 2.4e-09 36.7 1.3 7.6 6 2 3 9 9 7 6 TPR repeat TPR_16 PF13432.6 OAG23088.1 - 5.2e-28 97.4 2.0 6.8e-07 29.8 0.0 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.31 OAG23088.1 - 2.1e-27 95.0 5.0 6.6e-27 93.4 5.0 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 OAG23088.1 - 2.5e-25 88.8 16.2 1.1e-05 25.9 0.2 5.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23088.1 - 4.6e-23 79.9 11.3 5e-05 23.8 0.1 8.6 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23088.1 - 1.6e-22 77.8 11.9 0.0093 16.1 0.0 7.7 8 1 1 9 9 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAG23088.1 - 1.5e-20 72.0 12.2 0.0021 18.3 0.7 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAG23088.1 - 2.9e-17 62.6 4.1 1.5e-06 28.3 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG23088.1 - 4.5e-17 60.7 6.9 0.0021 17.9 0.0 7.0 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23088.1 - 2.7e-16 59.6 9.0 0.018 15.3 0.2 6.5 4 2 1 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG23088.1 - 2.7e-15 56.3 5.3 1.6e-05 25.1 0.1 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAG23088.1 - 2e-10 40.6 10.7 0.15 12.8 0.1 7.8 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG23088.1 - 4.4e-10 39.1 11.4 0.045 13.6 0.2 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG23088.1 - 4.6e-08 32.6 5.7 0.018 14.3 0.1 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG23088.1 - 1.1e-06 28.7 1.7 0.28 11.9 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG23088.1 - 3.9e-05 23.2 2.7 1.1 8.6 0.3 3.6 2 1 2 4 4 4 2 MalT-like TPR region TPR_20 PF14561.6 OAG23088.1 - 0.00016 22.0 11.0 2 8.8 0.1 4.9 3 3 2 5 5 5 3 Tetratricopeptide repeat DUF3597 PF12200.8 OAG23088.1 - 0.00028 21.4 0.1 0.00028 21.4 0.1 3.2 3 1 0 3 3 1 1 Domain of unknown function (DUF3597) HrpB1_HrpK PF09613.10 OAG23088.1 - 0.00087 18.9 0.9 3.8 7.2 0.0 4.0 2 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 OAG23088.1 - 0.00095 19.6 6.5 1.7 9.1 0.5 4.9 3 3 1 4 4 4 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 OAG23088.1 - 0.0013 18.7 5.5 15 5.8 0.0 5.3 3 2 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 OAG23088.1 - 0.0016 17.3 0.4 0.045 12.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.6 OAG23088.1 - 0.013 16.0 1.8 14 6.1 0.5 3.6 2 2 0 2 2 2 0 Alkyl sulfatase dimerisation DUF928 PF06051.12 OAG23088.1 - 0.016 15.1 1.5 0.1 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) PPR PF01535.20 OAG23088.1 - 0.028 14.6 1.1 16 6.1 0.0 4.3 5 0 0 5 5 3 0 PPR repeat TPR_21 PF09976.9 OAG23088.1 - 0.035 13.8 13.2 0.27 10.9 0.6 4.8 2 2 3 6 6 6 0 Tetratricopeptide repeat-like domain RRM_3 PF08777.11 OAG23088.1 - 0.037 14.1 0.5 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif MIT PF04212.18 OAG23088.1 - 0.049 13.7 3.3 7.3 6.7 0.0 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 OAG23088.1 - 0.06 13.4 0.3 5.2 7.2 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OAG23088.1 - 0.081 12.4 4.2 41 3.7 0.1 4.9 6 0 0 6 6 6 0 SHNi-TPR SRP_TPR_like PF17004.5 OAG23088.1 - 0.099 12.7 2.0 3.7 7.6 0.1 3.3 2 1 1 3 3 3 0 Putative TPR-like repeat DUF3856 PF12968.7 OAG23088.1 - 0.29 11.2 4.7 53 3.9 0.1 5.0 3 2 3 6 6 6 0 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.12 OAG23088.1 - 0.34 10.6 3.7 5.8 6.6 0.3 3.8 2 2 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2196 PF09962.9 OAG23090.1 - 1.5e-23 82.5 0.5 2.3e-23 81.9 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) DUF5320 PF17253.2 OAG23090.1 - 0.0071 17.4 0.9 0.013 16.5 0.9 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5320) CCDC144C PF14915.6 OAG23091.1 - 0.0009 18.4 14.8 0.0012 18.0 14.8 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 OAG23091.1 - 0.0093 16.0 17.0 0.035 14.1 7.8 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 OAG23091.1 - 0.014 15.6 24.4 0.34 11.1 6.1 2.5 1 1 1 2 2 2 0 Tropomyosin like MAD PF05557.13 OAG23091.1 - 0.017 13.5 17.8 0.021 13.2 17.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Seryl_tRNA_N PF02403.22 OAG23091.1 - 0.027 14.7 3.1 0.027 14.7 3.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 OAG23091.1 - 0.057 13.9 19.5 0.077 13.4 13.2 2.7 1 1 1 2 2 2 0 Fez1 Rootletin PF15035.6 OAG23091.1 - 0.079 13.0 24.2 0.77 9.7 6.4 2.3 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 OAG23091.1 - 0.14 12.7 18.0 1.5 9.3 6.0 3.0 2 2 0 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 OAG23091.1 - 0.14 12.1 10.3 0.24 11.3 1.8 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_13 PF13166.6 OAG23091.1 - 0.16 10.6 12.0 0.22 10.1 12.0 1.1 1 0 0 1 1 1 0 AAA domain DUF5082 PF16888.5 OAG23091.1 - 0.16 12.2 11.8 0.31 11.3 1.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) HemX PF04375.14 OAG23091.1 - 0.16 11.2 13.9 0.35 10.1 3.6 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase GvpG PF05120.12 OAG23091.1 - 0.17 11.9 8.1 0.32 11.1 0.1 3.4 3 1 0 3 3 3 0 Gas vesicle protein G Lzipper-MIP1 PF14389.6 OAG23091.1 - 0.42 11.0 13.9 0.28 11.5 5.7 3.0 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TMCO5 PF14992.6 OAG23091.1 - 0.49 9.9 14.0 0.037 13.6 5.4 2.0 1 1 0 1 1 1 0 TMCO5 family GAS PF13851.6 OAG23091.1 - 0.57 9.5 19.4 0.28 10.5 6.1 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OAG23091.1 - 0.66 8.8 21.9 0.84 8.5 7.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 OAG23091.1 - 0.81 10.1 7.9 0.71 10.3 1.1 3.5 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 OAG23091.1 - 0.94 9.6 21.9 1.9 8.6 6.0 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 OAG23091.1 - 1.4 8.9 18.3 0.66 10.0 2.5 2.6 3 0 0 3 3 2 0 FlxA-like protein Taxilin PF09728.9 OAG23091.1 - 1.5 7.9 15.8 1.2 8.3 4.4 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Csm1_N PF18504.1 OAG23091.1 - 1.5 9.2 18.2 2.3 8.6 2.0 4.1 2 2 3 5 5 4 0 Csm1 N-terminal domain DUF501 PF04417.12 OAG23091.1 - 1.8 8.4 7.0 3.2 7.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF501) WD40_alt PF14077.6 OAG23091.1 - 1.9 8.4 5.6 16 5.4 0.6 3.1 2 1 1 3 3 3 0 Alternative WD40 repeat motif GrpE PF01025.19 OAG23091.1 - 2.7 7.6 15.8 0.59 9.8 3.5 2.2 2 0 0 2 2 2 0 GrpE DUF2730 PF10805.8 OAG23091.1 - 2.8 8.1 8.4 4.3 7.5 1.4 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) SlyX PF04102.12 OAG23091.1 - 2.9 8.6 17.0 3.3 8.4 1.3 3.9 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 OAG23091.1 - 3.6 7.7 25.2 0.85 9.7 9.3 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OAG23091.1 - 4.8 7.4 18.9 0.52 10.5 5.7 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF5595 PF18077.1 OAG23091.1 - 5 7.3 6.2 20 5.4 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) Nup54 PF13874.6 OAG23091.1 - 6.1 7.0 16.5 0.39 10.8 4.6 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 ATG16 PF08614.11 OAG23091.1 - 6.3 7.0 29.6 0.57 10.4 11.9 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Tho2 PF11262.8 OAG23091.1 - 6.7 5.8 9.1 6.5 5.9 1.7 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 OAG23091.1 - 8.4 6.1 25.3 1.4e+02 2.1 24.9 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF948 PF06103.11 OAG23091.1 - 8.6 6.7 8.6 1.9 8.8 2.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 OAG23091.1 - 9.6 6.3 24.7 2.9 8.0 8.3 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Hid1 PF12722.7 OAG23092.1 - 0.8 7.8 2.1 0.86 7.6 2.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Scs3p PF10261.9 OAG23094.1 - 2e-74 250.2 5.9 2.8e-74 249.7 5.9 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Melibiase PF02065.18 OAG23095.1 - 1.7e-138 461.3 0.0 2.2e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 OAG23095.1 - 3.5e-78 262.7 0.0 4.8e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 OAG23095.1 - 1e-23 83.6 0.0 2.1e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 OAG23095.1 - 0.00054 19.1 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 PurS PF02700.14 OAG23096.1 - 0.057 13.6 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase Pkinase PF00069.25 OAG23097.1 - 2.3e-64 217.3 0.0 2.8e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23097.1 - 3.1e-36 125.0 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG23097.1 - 4e-07 29.6 0.0 6.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG23097.1 - 9.8e-05 21.3 0.0 0.00014 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAG23097.1 - 0.045 13.4 0.0 0.43 10.2 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG23097.1 - 0.067 13.1 0.0 0.3 11.0 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG23097.1 - 0.18 10.8 0.1 0.27 10.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAG23097.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_synthFbeta PF17759.1 OAG23098.1 - 9.2e-44 149.4 0.0 1.4e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAG23098.1 - 1.3e-32 111.8 0.4 4.5e-30 103.7 0.1 2.9 2 1 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAG23098.1 - 1.8e-23 83.1 0.0 3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAG23098.1 - 1.3e-17 63.8 0.0 8.8e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain His_Phos_1 PF00300.22 OAG23099.1 - 3.7e-13 49.6 0.0 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Exo_endo_phos_2 PF14529.6 OAG23099.1 - 0.0081 16.0 0.1 0.03 14.1 0.0 1.9 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase GFA PF04828.14 OAG23100.1 - 2.9e-20 72.4 0.4 2.9e-20 72.4 0.4 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Dabb PF07876.12 OAG23100.1 - 1.8e-19 70.1 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain CitMHS PF03600.16 OAG23101.1 - 5.6 6.1 10.9 9.7 5.3 10.9 1.5 1 1 0 1 1 1 0 Citrate transporter FAD_binding_4 PF01565.23 OAG23102.1 - 4.3e-18 65.4 0.7 8.6e-18 64.4 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG23102.1 - 7.6e-12 45.1 0.1 1.9e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like eIF-5_eIF-2B PF01873.17 OAG23105.1 - 3.5e-41 139.7 0.3 5.7e-41 139.1 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 NMD3 PF04981.13 OAG23105.1 - 0.045 13.2 0.4 0.045 13.2 0.4 1.8 2 0 0 2 2 2 0 NMD3 family zf-HYPF PF07503.12 OAG23105.1 - 0.17 11.7 1.0 17 5.2 0.1 2.5 2 0 0 2 2 2 0 HypF finger RNA_polI_A34 PF08208.11 OAG23105.1 - 3.1 7.9 16.5 4.7 7.2 16.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AIM24 PF01987.17 OAG23106.1 - 7.5e-48 163.0 0.8 9.1e-48 162.7 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Asp PF00026.23 OAG23107.1 - 5.2e-37 128.0 0.0 1.1e-34 120.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Rtf2 PF04641.12 OAG23107.1 - 0.00087 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger TAXi_N PF14543.6 OAG23107.1 - 0.041 14.1 0.7 0.12 12.6 0.3 1.9 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal RRM_1 PF00076.22 OAG23108.1 - 1.7e-20 72.6 0.0 7.8e-12 44.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG23108.1 - 0.0015 18.6 0.0 1.7 8.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Mitofilin PF09731.9 OAG23108.1 - 2 7.1 18.2 3.4 6.4 18.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HGTP_anticodon2 PF12745.7 OAG23108.1 - 2.3 7.6 9.0 4 6.9 9.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs N_BRCA1_IG PF16158.5 OAG23109.1 - 2.5e-32 111.6 0.1 1e-31 109.7 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 OAG23109.1 - 1.4e-15 56.8 59.8 1.1e-05 25.2 7.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type CsgE PF10627.9 OAG23109.1 - 0.16 12.2 0.6 8.8 6.6 0.0 2.7 2 1 0 2 2 2 0 Curli assembly protein CsgE DUF2756 PF10956.8 OAG23109.1 - 2.4 8.7 14.4 0.35 11.4 9.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) ALMT PF11744.8 OAG23109.1 - 9 5.0 12.1 3.4 6.4 8.9 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Rotamase_3 PF13616.6 OAG23110.1 - 1.2e-15 58.0 0.1 2.7e-15 56.9 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OAG23110.1 - 5.4e-14 52.9 0.3 1e-13 52.0 0.1 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OAG23110.1 - 0.0028 18.5 0.0 0.0038 18.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ank_2 PF12796.7 OAG23111.1 - 4.2e-16 59.3 0.0 1.2e-07 32.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23111.1 - 1.5e-08 35.0 0.0 0.037 14.6 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG23111.1 - 1.6e-07 31.4 0.1 0.0064 16.8 0.0 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG23111.1 - 9.5e-06 25.8 0.2 0.62 10.6 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OAG23111.1 - 9.5e-05 22.5 0.1 35 5.4 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Steroid_dh PF02544.16 OAG23112.1 - 7.1e-10 39.1 0.2 1.4e-09 38.1 0.2 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Aldo_ket_red PF00248.21 OAG23113.1 - 4.4e-65 219.8 0.0 5e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ku PF02735.16 OAG23114.1 - 3.1e-30 105.4 0.0 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 OAG23114.1 - 3.7e-29 101.3 0.0 7.2e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 OAG23114.1 - 1.6e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain DUF4921 PF16268.5 OAG23114.1 - 0.00025 20.0 0.0 0.088 11.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) VWA PF00092.28 OAG23114.1 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG23114.1 - 0.16 12.7 0.0 0.76 10.4 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain LapA_dom PF06305.11 OAG23115.1 - 0.13 12.1 0.7 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Formyl_trans_N PF00551.19 OAG23116.1 - 2.2e-39 135.1 0.4 2.9e-39 134.7 0.4 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAG23116.1 - 1.5e-08 34.2 0.0 5.1e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 OAG23116.1 - 1.8e-06 27.9 0.0 5.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain MGS PF02142.22 OAG23116.1 - 0.038 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain HET PF06985.11 OAG23117.1 - 1.5e-27 96.8 0.0 3e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.6 OAG23118.1 - 1.2e-24 87.8 0.0 1.9e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG23118.1 - 1.3e-14 54.3 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG23118.1 - 5.9e-05 22.9 1.6 0.00071 19.4 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ras PF00071.22 OAG23119.1 - 9.2e-57 191.2 0.1 1.2e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG23119.1 - 3e-32 111.4 0.0 4.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG23119.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG23119.1 - 1.1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG23119.1 - 2.8e-06 26.8 0.0 3.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG23119.1 - 1.3e-05 24.9 0.0 0.00059 19.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG23119.1 - 7.5e-05 22.7 0.1 0.0038 17.2 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 OAG23119.1 - 0.00024 21.0 0.4 0.0059 16.4 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAG23119.1 - 0.0023 17.7 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAG23119.1 - 0.006 15.9 0.1 0.062 12.6 0.0 2.1 2 0 0 2 2 2 1 Septin cobW PF02492.19 OAG23119.1 - 0.0068 16.0 0.0 0.034 13.7 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAG23119.1 - 0.0078 16.6 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OAG23119.1 - 0.0082 15.6 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAG23119.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG23119.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG23119.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG23119.1 - 0.026 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAG23119.1 - 0.068 13.1 0.2 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 OAG23119.1 - 0.079 13.3 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 TniB PF05621.11 OAG23119.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 OAG23119.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 OAG23119.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 OAG23119.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase EamA PF00892.20 OAG23120.1 - 1.8e-12 47.6 29.4 3.9e-08 33.6 1.4 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 OAG23120.1 - 5e-08 32.5 0.1 5e-08 32.5 0.1 2.5 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 OAG23120.1 - 6.4e-07 29.2 1.2 6.4e-07 29.2 1.2 2.2 3 0 0 3 3 3 1 Solute carrier family 35 DUF3955 PF13127.6 OAG23120.1 - 5e-06 26.2 2.1 2.4e-05 24.0 2.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) CitMHS_2 PF16980.5 OAG23120.1 - 0.0011 17.7 1.5 0.18 10.4 0.1 2.3 2 0 0 2 2 2 2 Putative citrate transport TPT PF03151.16 OAG23120.1 - 0.0081 15.5 1.7 0.032 13.6 0.2 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 OAG23120.1 - 0.7 9.0 10.3 0.27 10.4 7.6 1.7 2 0 0 2 2 2 0 UAA transporter family TruB_N PF01509.18 OAG23121.1 - 1.7e-45 155.0 0.4 1e-44 152.5 0.0 2.3 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG23121.1 - 3.2e-06 27.2 0.0 6.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DnaJ PF00226.31 OAG23122.1 - 1.9e-17 63.1 0.4 1.9e-17 63.1 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain Fmp27_WPPW PF10359.9 OAG23122.1 - 2 7.2 10.0 3.1 6.6 10.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 OAG23122.1 - 2.2 7.3 8.7 3.8 6.5 8.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 OAG23122.1 - 6.1 5.3 13.7 9.3 4.7 13.7 1.2 1 0 0 1 1 1 0 Macoilin family DNMT1-RFD PF12047.8 OAG23123.1 - 0.00046 20.3 0.0 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Nucleo_P87 PF07267.11 OAG23124.1 - 0.048 12.5 0.1 0.056 12.3 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAF1C_H4-bd PF12265.8 OAG23125.1 - 9e-15 54.7 0.1 4.8e-14 52.4 0.0 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG23125.1 - 2.2e-14 53.6 9.8 1e-06 29.3 0.3 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23125.1 - 8.5e-08 32.4 1.2 0.00025 21.3 0.1 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OAG23125.1 - 0.0082 14.2 0.2 0.012 13.7 0.2 1.2 1 0 0 1 1 1 1 IKI3 family UL41A PF17591.2 OAG23125.1 - 0.042 14.0 0.3 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL41A Ras PF00071.22 OAG23126.1 - 2.9e-31 108.3 0.2 4.6e-31 107.6 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG23126.1 - 1.1e-23 83.8 0.1 2.9e-23 82.4 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG23126.1 - 1.4e-06 27.9 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG23126.1 - 7.8e-05 22.1 0.2 0.00015 21.2 0.2 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OAG23126.1 - 0.015 14.1 1.2 1.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) CrgA PF06781.12 OAG23126.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA G-alpha PF00503.20 OAG23126.1 - 0.27 10.3 5.7 0.7 9.0 0.1 2.7 1 1 2 3 3 3 0 G-protein alpha subunit Presenilin PF01080.17 OAG23126.1 - 8.7 5.0 7.6 14 4.4 7.6 1.3 1 0 0 1 1 1 0 Presenilin EXOSC1 PF10447.9 OAG23127.1 - 6.9e-16 58.8 2.7 7.4e-11 42.6 0.7 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OAG23127.1 - 1.6e-11 43.8 0.1 3.2e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region SAM_1 PF00536.30 OAG23128.1 - 2.3e-13 50.3 0.0 3.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAG23128.1 - 3.3e-13 50.1 0.0 7.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 OAG23128.1 - 4.2e-13 49.2 0.0 1.1e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TMF_TATA_bd PF12325.8 OAG23128.1 - 0.0024 18.1 0.2 0.0042 17.3 0.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding YabA PF06156.13 OAG23128.1 - 0.022 15.4 0.0 0.038 14.6 0.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA AAA_21 PF13304.6 OAG23128.1 - 0.08 12.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DBR1 PF05011.13 OAG23128.1 - 0.21 12.0 0.9 1.1e+02 3.2 0.0 3.9 4 1 0 4 4 4 0 Lariat debranching enzyme, C-terminal domain Pneumo_att_G PF05539.11 OAG23128.1 - 6.9 6.2 12.4 0.19 11.3 5.4 1.8 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G EnY2 PF10163.9 OAG23129.1 - 0.14 12.6 0.0 0.45 10.9 0.0 2.0 1 1 0 1 1 1 0 Transcription factor e(y)2 AAA PF00004.29 OAG23130.1 - 8.6e-98 323.9 0.0 1.5e-47 161.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG23130.1 - 8.3e-22 76.7 3.3 2e-12 46.7 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OAG23130.1 - 1e-18 67.3 1.1 2.6e-18 66.0 0.5 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 OAG23130.1 - 3.4e-14 53.3 0.0 1e-07 32.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG23130.1 - 7e-14 51.9 0.0 6.6e-06 26.0 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG23130.1 - 2.2e-12 47.7 0.0 9.9e-05 22.8 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 OAG23130.1 - 6.1e-12 45.9 0.0 1.8e-05 24.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OAG23130.1 - 1.3e-10 41.5 0.5 2e-05 24.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG23130.1 - 2.5e-09 36.8 0.6 0.0015 17.9 0.0 3.0 3 1 0 3 3 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OAG23130.1 - 5.6e-09 36.4 0.4 0.046 14.0 0.0 4.2 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 OAG23130.1 - 2.1e-07 30.6 0.1 5e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 OAG23130.1 - 3.7e-07 29.7 0.2 0.23 10.8 0.0 3.4 3 0 0 3 3 3 2 KaiC Mg_chelatase PF01078.21 OAG23130.1 - 4e-07 29.6 0.3 0.035 13.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG23130.1 - 5.4e-07 30.0 0.0 0.025 15.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAG23130.1 - 1e-06 28.6 0.0 0.038 13.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OAG23130.1 - 1.3e-06 28.9 0.0 0.058 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG23130.1 - 1.8e-06 27.7 3.5 0.75 9.3 0.1 4.8 3 2 1 5 5 5 2 AAA domain AAA_14 PF13173.6 OAG23130.1 - 2.2e-06 27.7 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAG23130.1 - 5.4e-06 26.0 0.0 0.04 13.4 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 OAG23130.1 - 1.3e-05 25.1 0.2 0.00012 22.0 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 OAG23130.1 - 1.8e-05 24.6 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 OAG23130.1 - 2.2e-05 23.8 0.0 0.017 14.3 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 OAG23130.1 - 3e-05 23.2 0.1 0.1 11.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 OAG23130.1 - 4.8e-05 23.1 0.1 0.43 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 OAG23130.1 - 5.7e-05 23.1 0.0 0.33 10.8 0.0 3.4 4 0 0 4 4 4 2 Bacterial dnaA protein AAA_28 PF13521.6 OAG23130.1 - 7e-05 23.1 0.0 0.47 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OAG23130.1 - 0.00014 22.4 0.0 0.48 10.9 0.0 3.4 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 OAG23130.1 - 0.00019 21.0 0.4 0.47 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 OAG23130.1 - 0.00022 21.7 0.1 0.6 10.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 OAG23130.1 - 0.0003 20.8 0.0 1 9.4 0.0 2.8 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 OAG23130.1 - 0.00043 20.3 0.0 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAG23130.1 - 0.00044 20.1 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG23130.1 - 0.00069 19.5 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OAG23130.1 - 0.00096 18.5 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAG23130.1 - 0.0012 18.9 0.0 2.3 8.1 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAG23130.1 - 0.0019 18.0 0.3 1.8 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG23130.1 - 0.0024 17.8 0.1 1.4 8.8 0.0 2.9 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 OAG23130.1 - 0.0072 15.5 0.0 1.7 7.8 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain Viral_helicase1 PF01443.18 OAG23130.1 - 0.0093 15.7 0.0 0.68 9.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OAG23130.1 - 0.013 14.8 0.0 6 6.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 OAG23130.1 - 0.013 15.8 1.5 8.8 6.7 0.0 3.4 3 1 0 4 4 2 0 AAA domain KAP_NTPase PF07693.14 OAG23130.1 - 0.019 14.2 0.3 0.91 8.7 0.0 2.8 2 2 0 3 3 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 OAG23130.1 - 0.022 14.9 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UFD1 PF03152.14 OAG23130.1 - 0.029 13.9 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 OAG23130.1 - 0.03 14.2 0.5 6.8 6.6 0.0 3.6 3 0 0 3 3 3 0 NTPase IPT PF01745.16 OAG23130.1 - 0.03 13.7 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.12 OAG23130.1 - 0.033 13.8 0.1 2 8.0 0.0 3.2 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 OAG23130.1 - 0.091 11.7 0.2 9.1 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region SLAC1 PF03595.17 OAG23131.1 - 2.8e-66 224.0 31.9 3.2e-66 223.8 31.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Bax1-I PF01027.20 OAG23131.1 - 1.2 8.9 24.6 2.6 7.8 12.3 2.4 1 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Asp PF00026.23 OAG23133.1 - 9.9e-39 133.6 0.0 1.3e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAG23133.1 - 0.036 14.7 0.9 4.3 8.1 0.6 3.3 2 1 0 2 2 2 0 Aspartyl protease TAXi_N PF14543.6 OAG23133.1 - 0.039 14.2 0.2 0.089 13.0 0.2 1.7 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Methyltransf_2 PF00891.18 OAG23134.1 - 7.6e-27 94.0 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 OAG23134.1 - 0.16 13.0 0.0 46 5.1 0.0 3.0 2 2 0 2 2 2 0 Methyltransferase domain Nha1_C PF08619.10 OAG23135.1 - 1.5e-97 327.7 45.9 1.5e-97 327.7 45.9 2.1 2 1 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 OAG23135.1 - 2.8e-76 256.8 23.0 3.4e-76 256.5 23.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PRP4 PF08799.11 OAG23135.1 - 0.041 13.4 7.4 1.5 8.5 0.5 2.8 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like TFIIE-A_C PF11521.8 OAG23135.1 - 0.077 13.3 0.1 0.077 13.3 0.1 3.9 5 0 0 5 5 5 0 C-terminal general transcription factor TFIIE alpha DUF4190 PF13828.6 OAG23135.1 - 0.36 10.6 0.0 0.36 10.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Arrestin_C PF02752.22 OAG23136.1 - 4.6e-21 75.7 0.0 2.2e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG23136.1 - 1.3e-08 35.0 0.0 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF5569 PF17729.1 OAG23136.1 - 0.26 11.2 2.6 0.43 10.4 2.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5569) PTCB-BRCT PF12738.7 OAG23137.1 - 1.4e-48 162.7 0.5 4.5e-23 81.0 0.0 4.6 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 OAG23137.1 - 1.3e-34 118.4 0.0 3.8e-11 43.2 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG23137.1 - 8.4e-14 51.8 0.0 0.017 15.5 0.0 5.1 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG23137.1 - 1.1e-06 28.8 0.1 0.49 10.7 0.0 3.8 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OAG23137.1 - 0.00019 21.3 0.0 0.2 11.6 0.0 3.7 5 0 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain DIOX_N PF14226.6 OAG23138.1 - 9.2e-22 78.0 0.0 1.6e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG23138.1 - 3.2e-16 59.7 0.0 1.6e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MKT1_N PF12247.8 OAG23139.1 - 2.5e-27 95.1 0.1 4.4e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 OAG23139.1 - 5.2e-08 33.1 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAG23139.1 - 0.00098 19.6 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Cas_Cas02710 PF09670.10 OAG23139.1 - 0.045 12.6 0.2 0.067 12.0 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) MFS_1 PF07690.16 OAG23140.1 - 5e-18 65.2 17.4 7e-18 64.7 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 OAG23141.1 - 3.3e-45 155.0 0.1 4.4e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HET PF06985.11 OAG23142.1 - 8e-21 74.9 0.0 8.2e-20 71.6 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIG-L PF02585.17 OAG23144.1 - 3.7e-25 89.1 0.1 6.3e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase F-box PF00646.33 OAG23145.1 - 0.00077 19.3 0.3 0.00077 19.3 0.3 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG23145.1 - 0.00094 19.0 0.2 0.00094 19.0 0.2 2.0 2 0 0 2 2 2 1 F-box-like DZR PF12773.7 OAG23145.1 - 0.8 9.8 9.2 3.7 7.6 7.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Phasin PF05597.11 OAG23147.1 - 0.0076 16.3 0.6 0.027 14.5 0.6 1.9 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) TFIIE-A_C PF11521.8 OAG23147.1 - 0.084 13.2 2.4 0.39 11.1 2.4 2.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha HalX PF08663.10 OAG23147.1 - 0.37 11.1 6.1 29 5.1 4.0 2.8 2 0 0 2 2 2 0 HalX domain DUF3381 PF11861.8 OAG23147.1 - 0.86 9.4 4.5 13 5.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PPP4R2 PF09184.11 OAG23147.1 - 1.6 8.3 16.4 3.5 7.1 8.8 2.3 2 0 0 2 2 2 0 PPP4R2 Grg1 PF11034.8 OAG23147.1 - 1.8 8.8 7.6 6.6 7.0 5.8 2.9 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 XRN_M PF17846.1 OAG23147.1 - 5.7 5.8 6.2 18 4.2 0.1 2.1 2 0 0 2 2 2 0 Xrn1 helical domain RRM_1 PF00076.22 OAG23148.1 - 1.3e-12 47.4 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.19 OAG23149.1 - 0.014 15.7 2.7 0.1 12.9 2.7 2.1 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Helo_like_N PF17111.5 OAG23149.1 - 0.11 11.8 1.8 0.15 11.4 1.8 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Rick_17kDa_Anti PF05433.15 OAG23149.1 - 1.1 9.1 5.8 17 5.3 2.2 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain GFO_IDH_MocA PF01408.22 OAG23150.1 - 6.5e-19 68.9 0.0 1e-18 68.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG23150.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 OAG23150.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3443 PF11925.8 OAG23150.1 - 0.026 13.4 0.2 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3443) Response_reg PF00072.24 OAG23150.1 - 0.092 12.9 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Response regulator receiver domain MFS_1 PF07690.16 OAG23151.1 - 1.8e-22 79.8 14.6 1.8e-22 79.8 14.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily CPP1-like PF11833.8 OAG23151.1 - 8.5 6.0 6.6 2.9 7.5 1.9 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TRAP_alpha PF03896.16 OAG23152.1 - 2.2e-08 33.7 0.3 1.1e-07 31.4 0.3 1.9 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 OAG23152.1 - 0.0062 16.0 0.1 0.019 14.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1616) DcpS_C PF11969.8 OAG23154.1 - 3.2e-16 59.8 4.7 5.1e-08 33.4 0.8 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 OAG23154.1 - 2.5e-13 50.3 0.5 6.9e-13 48.9 0.5 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 OAG23154.1 - 9e-13 48.8 0.8 2.9e-12 47.2 0.8 1.8 1 1 0 1 1 1 1 HIT domain HA2 PF04408.23 OAG23155.1 - 1.1e-19 70.7 3.1 9.2e-19 67.7 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG23155.1 - 8.3e-17 61.3 0.0 1.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG23155.1 - 3.1e-13 50.0 0.0 1e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.22 OAG23155.1 - 2.2e-12 47.3 0.0 5.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 OAG23155.1 - 1.4e-08 34.7 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 OAG23155.1 - 0.0013 19.0 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 OAG23155.1 - 0.0017 18.6 0.7 0.0067 16.7 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG23155.1 - 0.023 14.4 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain UBA PF00627.31 OAG23155.1 - 0.083 12.8 0.3 6.4 6.8 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain AAA_23 PF13476.6 OAG23155.1 - 0.1 13.1 2.3 0.23 12.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAG23155.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 KaiC tRNA_anti-like PF12869.7 OAG23155.1 - 8.3 6.0 6.9 1.1 8.9 0.2 2.6 3 0 0 3 3 3 0 tRNA_anti-like Glyco_hydro_61 PF03443.14 OAG23156.1 - 5.1e-41 140.9 0.1 6.2e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CTU2 PF10288.9 OAG23157.1 - 4.5e-14 52.6 0.9 4.7e-12 46.1 0.0 2.7 3 0 0 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 Vps39_2 PF10367.9 OAG23157.1 - 0.19 12.2 2.4 4.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Lung_7-TM_R PF06814.13 OAG23158.1 - 6.6e-69 232.4 19.5 8.7e-69 232.0 19.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TraA PF05513.11 OAG23158.1 - 0.16 12.3 2.1 0.82 10.0 0.4 2.5 2 0 0 2 2 2 0 TraA GCV_T PF01571.21 OAG23159.1 - 2.7e-06 27.0 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DIOX_N PF14226.6 OAG23160.1 - 0.0016 19.2 0.1 0.0033 18.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CF222 PF15661.5 OAG23160.1 - 0.0026 16.7 0.1 0.0038 16.2 0.1 1.1 1 0 0 1 1 1 1 C6orf222, uncharacterised family 2OG-FeII_Oxy PF03171.20 OAG23160.1 - 0.0042 17.5 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 OAG23161.1 - 8.1e-13 48.9 0.4 5.9e-09 36.4 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Asp PF00026.23 OAG23162.1 - 2.7e-38 132.2 0.0 6.1e-26 91.6 0.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG23162.1 - 1.1e-05 25.8 0.2 0.00011 22.5 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG23162.1 - 0.0025 18.4 0.0 5.2 7.8 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG23162.1 - 0.065 13.8 0.0 9.2 6.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SH3_1 PF00018.28 OAG23163.1 - 6.9e-06 25.6 0.0 1.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Sugar_tr PF00083.24 OAG23164.1 - 4.9e-121 404.7 18.5 7.5e-121 404.1 18.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG23164.1 - 3.2e-23 82.3 45.1 1.2e-12 47.4 11.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MeaB PF03308.16 OAG23165.1 - 1.6e-09 37.2 0.0 2.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 OAG23165.1 - 9.9e-06 25.4 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 OAG23165.1 - 6.1e-05 22.4 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 OAG23165.1 - 0.0001 22.5 1.2 0.0018 18.4 1.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG23165.1 - 0.00046 20.7 0.0 0.0008 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG23165.1 - 0.00053 20.4 0.0 0.00092 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAG23165.1 - 0.0016 18.1 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 OAG23165.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 OAG23165.1 - 0.0052 16.5 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_30 PF13604.6 OAG23165.1 - 0.011 15.4 0.1 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OAG23165.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 OAG23165.1 - 0.02 15.3 0.1 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain LysR_substrate PF03466.20 OAG23165.1 - 0.02 14.2 0.1 0.084 12.2 0.1 1.8 1 1 1 2 2 2 0 LysR substrate binding domain Viral_helicase1 PF01443.18 OAG23165.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 OAG23165.1 - 0.044 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OAG23165.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG23165.1 - 0.093 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OAG23165.1 - 0.11 12.4 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fungal_trans PF04082.18 OAG23166.1 - 4.1e-25 88.3 1.8 6.5e-25 87.7 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23166.1 - 8.1e-08 32.3 10.1 1.3e-07 31.6 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 OAG23166.1 - 1.5e-07 31.5 0.0 3.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Opy2 PF09463.10 OAG23166.1 - 9 6.7 7.8 19 5.7 7.8 1.5 1 0 0 1 1 1 0 Opy2 protein Zn_clus PF00172.18 OAG23168.1 - 2.7e-07 30.6 11.6 4.4e-07 29.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 OAG23169.1 - 7.3e-58 195.3 0.0 1.1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAG23169.1 - 1.6e-14 53.7 0.0 4.6e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG23169.1 - 4.4e-11 43.0 0.0 2.2e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG23169.1 - 9.7e-08 32.0 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 OAG23169.1 - 0.0019 18.0 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV PH PF00169.29 OAG23170.1 - 8.3e-32 109.8 1.7 7.6e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OAG23170.1 - 2.2e-10 40.9 4.6 0.0011 19.4 0.3 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 OAG23170.1 - 8e-10 39.1 1.7 6.3e-06 26.6 0.3 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OAG23170.1 - 1.9e-07 31.3 0.6 1.8e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 OAG23170.1 - 5.9e-06 26.3 1.2 0.00012 22.1 0.3 2.3 2 0 0 2 2 2 1 PH domain Myosin_TH1 PF06017.13 OAG23170.1 - 0.05 13.3 0.3 0.087 12.5 0.3 1.3 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding PH_12 PF16457.5 OAG23170.1 - 0.065 13.8 0.2 5.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 OAG23170.1 - 0.11 12.3 0.2 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain CorA PF01544.18 OAG23171.1 - 9.7e-11 41.5 1.0 1.7e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4449 PF14613.6 OAG23172.1 - 1.8e-68 229.7 5.8 1.8e-68 229.7 5.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) JHBP PF06585.11 OAG23172.1 - 0.056 12.6 3.9 0.075 12.2 2.3 2.0 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) DUF5133 PF17196.4 OAG23172.1 - 0.13 12.5 0.1 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Prp18 PF02840.15 OAG23172.1 - 0.48 10.5 0.0 0.48 10.5 0.0 3.9 3 1 1 4 4 4 0 Prp18 domain Herpes_BLRF2 PF05812.12 OAG23172.1 - 2.2 8.4 6.5 1.1 9.3 0.1 3.2 3 1 1 4 4 4 0 Herpesvirus BLRF2 protein RTA1 PF04479.13 OAG23173.1 - 1.1e-65 221.1 7.9 1.5e-65 220.7 7.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Cyclase PF04199.13 OAG23174.1 - 2.5e-12 47.2 0.1 3.7e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase PI-PLC-X PF00388.19 OAG23175.1 - 3.8e-46 156.3 0.0 5.8e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG23175.1 - 1e-37 129.0 0.0 2e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAG23175.1 - 0.00087 19.6 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Herpes_gE PF02480.16 OAG23175.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.16 OAG23176.1 - 7e-11 41.6 18.7 7e-11 41.6 18.7 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG23176.1 - 1.9e-05 24.4 3.1 4.2e-05 23.3 3.1 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 2OG-FeII_Oxy_2 PF13532.6 OAG23177.1 - 3e-22 79.8 0.0 4.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_C_34 PF17929.1 OAG23177.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 OAG23179.1 - 5.1e-36 124.2 0.0 8.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG23179.1 - 2.4e-09 37.0 6.0 9.8e-08 31.8 0.2 2.5 2 0 0 2 2 2 2 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG23179.1 - 0.0027 18.6 0.1 0.0071 17.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CNOT1_HEAT PF16418.5 OAG23179.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3425 PF11905.8 OAG23183.1 - 4.6e-18 65.4 0.8 4.6e-18 65.4 0.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) DUF4349 PF14257.6 OAG23183.1 - 0.016 14.7 0.8 0.024 14.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) bZIP_1 PF00170.21 OAG23183.1 - 0.028 14.5 7.0 0.052 13.6 4.6 2.1 2 0 0 2 2 2 0 bZIP transcription factor Pox_A_type_inc PF04508.12 OAG23183.1 - 0.34 10.9 1.7 0.92 9.5 1.7 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Say1_Mug180 PF10340.9 OAG23184.1 - 1.4e-23 83.4 0.0 1.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 OAG23184.1 - 5.6e-23 81.9 0.0 7.2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold P33MONOX PF15302.6 OAG23184.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase AAA_lid_2 PF17863.1 OAG23185.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA lid domain Porphobil_deam PF01379.20 OAG23186.1 - 4.4e-72 241.9 0.0 5.8e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAG23186.1 - 2.6e-16 59.7 3.2 1e-14 54.6 3.2 2.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PLAC8 PF04749.17 OAG23187.1 - 3.1e-23 82.6 9.9 4.6e-23 82.1 9.9 1.3 1 0 0 1 1 1 1 PLAC8 family DUF2613 PF11021.8 OAG23188.1 - 0.088 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF908 PF06012.12 OAG23188.1 - 2.7 7.3 9.7 3.2 7.1 9.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Macoilin PF09726.9 OAG23188.1 - 4.1 5.9 16.8 4.6 5.7 16.8 1.0 1 0 0 1 1 1 0 Macoilin family TIP120 PF08623.10 OAG23189.1 - 2e-64 216.4 1.2 3.3e-63 212.4 0.2 3.5 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAG23189.1 - 1.1e-13 51.3 10.3 0.27 11.7 2.1 8.4 8 2 3 11 11 11 5 HEAT repeats MMS19_C PF12460.8 OAG23189.1 - 1.7e-06 27.4 8.0 0.3 10.2 0.0 4.8 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 OAG23189.1 - 2.5e-06 27.5 1.6 2.5 8.0 0.0 5.6 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OAG23189.1 - 7.9e-05 23.2 0.0 19 5.9 0.0 6.3 5 2 1 6 6 6 0 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 OAG23189.1 - 0.00017 21.6 2.5 1.8 8.5 0.0 5.4 6 1 0 6 6 6 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 OAG23189.1 - 0.0033 17.5 3.7 1.2 9.2 0.0 5.5 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 OAG23189.1 - 0.0033 17.0 9.6 1.2 8.6 0.1 5.7 5 1 0 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II IFRD PF05004.13 OAG23189.1 - 0.0044 16.2 1.5 0.035 13.2 0.6 3.0 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAG23189.1 - 0.0051 17.3 25.7 34 5.1 0.0 11.3 13 1 1 14 14 13 0 HEAT-like repeat HEAT PF02985.22 OAG23189.1 - 0.0073 16.5 24.2 1.1 9.7 0.1 10.0 13 0 0 13 13 11 1 HEAT repeat Importin_rep_4 PF18808.1 OAG23189.1 - 0.025 14.9 2.0 1.4 9.3 0.0 4.1 3 0 0 3 3 3 0 Importin repeat Voldacs PF03517.13 OAG23189.1 - 0.42 10.7 3.4 0.48 10.5 1.0 2.3 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling RTP1_C1 PF10363.9 OAG23189.1 - 0.83 9.9 7.5 7.4 6.8 0.0 5.2 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4965 PF16335.5 OAG23191.1 - 9.4e-63 211.0 0.5 2e-62 209.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAG23191.1 - 9.2e-54 182.3 0.7 2e-53 181.2 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAG23191.1 - 2.2e-43 148.7 2.1 7.6e-43 146.9 2.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) Glyco_hydr_116N PF12215.8 OAG23191.1 - 0.0016 18.0 0.4 0.0056 16.2 0.0 2.0 3 0 0 3 3 3 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Methyltransf_25 PF13649.6 OAG23192.1 - 5.7e-09 36.6 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG23192.1 - 4.7e-06 27.2 0.0 1.2e-05 25.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG23192.1 - 0.00097 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG23192.1 - 0.0049 17.6 0.0 0.013 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain LIM PF00412.22 OAG23193.1 - 3.7e-19 68.7 19.9 1.9e-10 40.8 3.6 2.5 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 OAG23193.1 - 0.0038 16.9 0.2 0.75 9.5 0.1 2.5 2 0 0 2 2 2 2 WRC DUF2321 PF10083.9 OAG23193.1 - 3.3 7.3 9.9 0.16 11.6 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) NAD_binding_5 PF07994.12 OAG23194.1 - 3.6e-146 486.6 0.2 4.2e-146 486.4 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAG23194.1 - 5.8e-45 152.0 0.7 1.4e-44 150.8 0.5 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase MIS13 PF08202.11 OAG23196.1 - 6.7e-45 153.7 0.0 1.6e-44 152.4 0.0 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family PS_Dcarbxylase PF02666.15 OAG23197.1 - 4.2e-57 192.9 0.0 6.3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAG23197.1 - 7.5e-42 141.8 0.1 1.9e-19 69.9 0.1 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 OAG23197.1 - 0.0083 16.6 2.5 0.016 15.6 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG23197.1 - 0.036 13.6 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAG23197.1 - 0.082 12.9 0.9 0.81 9.8 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain G-alpha PF00503.20 OAG23199.1 - 1.4e-122 409.2 2.4 1.7e-122 409.0 2.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG23199.1 - 4.2e-15 55.6 2.4 2.4e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 OAG23199.1 - 0.0004 20.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 OAG23199.1 - 0.0027 17.1 4.2 0.062 12.6 0.1 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OAG23199.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAG23199.1 - 0.021 15.0 0.2 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OAG23199.1 - 0.056 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 OAG23199.1 - 0.08 12.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 OAG23199.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAG23199.1 - 0.14 12.3 0.1 9 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase CFEM PF05730.11 OAG23201.1 - 6.1e-05 23.0 4.9 0.0001 22.3 4.9 1.3 1 0 0 1 1 1 1 CFEM domain GNAT_acetyltr_2 PF13718.6 OAG23201.1 - 0.018 14.5 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF5427 PF10310.9 OAG23201.1 - 6.4 5.6 12.8 12 4.7 12.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Transketolase_N PF00456.21 OAG23202.1 - 2.2e-152 506.8 0.2 2.9e-152 506.4 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG23202.1 - 1.5e-45 155.1 0.0 2.9e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG23202.1 - 8.4e-13 48.3 0.0 2.5e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG23202.1 - 0.00015 21.1 0.1 0.00026 20.3 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 OAG23202.1 - 0.0015 17.5 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 OAG23202.1 - 0.022 14.0 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase GtrA PF04138.14 OAG23202.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein GST_N_4 PF17172.4 OAG23203.1 - 6.4e-21 75.0 0.1 2.7e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAG23203.1 - 5.5e-13 48.5 0.1 1e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAG23203.1 - 5e-08 33.3 0.0 1.1e-07 32.2 0.0 1.5 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 OAG23203.1 - 8.2e-07 29.3 0.6 2.1e-06 28.0 0.4 1.7 1 1 1 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 OAG23203.1 - 8.6e-06 25.7 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 OAG23204.1 - 1.1e-11 45.3 0.0 3.5e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG23204.1 - 4.9e-10 39.5 0.0 1e-09 38.4 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG23204.1 - 9.1e-09 35.9 0.0 5e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG23204.1 - 8.5e-08 32.9 0.0 2.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG23204.1 - 1.6e-07 31.2 0.0 4.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG23204.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 OAG23204.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase MetW PF07021.12 OAG23204.1 - 0.045 13.4 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAG23204.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OAG23204.1 - 0.053 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 OAG23204.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_33 PF10017.9 OAG23204.1 - 0.12 11.5 0.0 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent N2227 PF07942.12 OAG23204.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein p450 PF00067.22 OAG23205.1 - 2.2e-61 208.0 0.0 3e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1264 PF06884.11 OAG23206.1 - 2.2e-77 258.5 0.3 2.6e-77 258.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF4598 PF15370.6 OAG23207.1 - 1.2e-21 77.2 1.4 1.2e-21 77.2 1.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) SAP18 PF06487.12 OAG23207.1 - 0.037 14.2 2.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) Cut12 PF11500.8 OAG23207.1 - 2.7 7.9 14.5 0.21 11.5 9.3 1.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein GEMIN8 PF15348.6 OAG23207.1 - 4.1 7.7 8.7 1.9 8.7 6.8 1.4 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 IF4E PF01652.18 OAG23208.1 - 4.1e-33 114.4 0.8 5.3e-33 114.1 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Band_7 PF01145.25 OAG23209.1 - 5.1e-25 88.5 8.3 1.2e-24 87.3 8.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAG23209.1 - 9.5e-05 21.6 3.0 0.00013 21.2 3.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 OAG23209.1 - 0.0059 16.5 1.4 0.0093 15.9 1.4 1.4 1 0 0 1 1 1 1 GatB domain zf-C2H2_aberr PF17017.5 OAG23210.1 - 0.00041 20.5 1.5 0.001 19.3 0.1 2.1 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG23210.1 - 0.012 16.1 13.3 1.4 9.5 0.6 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type ZapB PF06005.12 OAG23210.1 - 0.32 11.4 7.1 0.7 10.4 5.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB zf-C2H2_4 PF13894.6 OAG23210.1 - 0.36 11.8 12.8 3.2 8.8 1.9 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG23212.1 - 0.00025 21.3 9.2 0.0036 17.7 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG23212.1 - 0.00092 19.9 6.9 0.12 13.3 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3632 PF12311.8 OAG23213.1 - 1.6e-10 41.7 0.0 2.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glycophorin_A PF01102.18 OAG23215.1 - 0.0032 17.7 0.4 0.0057 16.9 0.4 1.5 1 0 0 1 1 1 1 Glycophorin A CN_hydrolase PF00795.22 OAG23216.1 - 3.6e-44 151.1 0.0 4.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase rpo132 PF12415.8 OAG23216.1 - 0.075 12.3 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Amidohydro_1 PF01979.20 OAG23217.1 - 6.4e-22 78.3 0.0 1.4e-21 77.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG23217.1 - 1.5e-08 34.5 0.1 3.5e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Staphylcoagulse PF04022.12 OAG23217.1 - 0.13 11.8 1.0 0.35 10.4 1.0 1.8 1 0 0 1 1 1 0 Staphylocoagulase repeat Beta-lactamase PF00144.24 OAG23219.1 - 1e-41 143.3 0.0 2.4e-41 142.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase XPG_I PF00867.18 OAG23221.1 - 1.3e-26 92.7 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG23221.1 - 0.00012 22.5 0.0 0.00031 21.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain UIM PF02809.20 OAG23221.1 - 0.0028 17.4 7.3 0.0082 16.0 7.3 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif XPG_I_2 PF12813.7 OAG23221.1 - 0.0082 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Apc13p PF05839.11 OAG23222.1 - 1.9e-32 111.3 0.1 2.5e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Apc13p protein Antigen_Bd37 PF11641.8 OAG23222.1 - 0.25 10.8 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein GFA PF04828.14 OAG23223.1 - 4.5e-14 52.6 0.2 6.2e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SET PF00856.28 OAG23224.1 - 1.1e-10 42.2 0.0 6.1e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 SET domain 4HBT PF03061.22 OAG23226.1 - 2.3e-11 43.9 0.0 3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAG23226.1 - 1.1e-07 32.4 0.0 1.4e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAG23226.1 - 4.8e-06 26.0 2.5 1.7e-05 24.2 2.0 1.9 1 1 1 2 2 2 1 Acyl-ACP thioesterase 4HBT_3 PF13622.6 OAG23226.1 - 0.079 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily PseudoU_synth_2 PF00849.22 OAG23227.1 - 3.7e-27 95.4 0.0 6.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OAG23227.1 - 0.00017 21.3 0.1 0.00041 20.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain DUF2263 PF10021.9 OAG23228.1 - 2.2e-15 57.3 0.0 5.6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PAN_4 PF14295.6 OAG23229.1 - 0.00063 19.6 0.5 0.00063 19.6 0.5 2.7 2 0 0 2 2 2 1 PAN domain MANEC PF07502.14 OAG23229.1 - 0.035 14.4 1.5 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 MANEC domain PAN_2 PF08276.11 OAG23229.1 - 0.11 12.6 3.4 0.1 12.7 0.8 2.2 2 0 0 2 2 2 0 PAN-like domain WD40 PF00400.32 OAG23230.1 - 8.1e-26 89.8 5.5 1.3e-06 29.0 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23230.1 - 2e-05 24.8 0.1 5.7 7.3 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG23230.1 - 0.027 13.8 0.0 5 6.4 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 OAG23230.1 - 0.031 13.0 0.3 1.9 7.1 0.0 3.3 3 1 0 3 3 3 0 Nup133 N terminal like BBS2_Mid PF14783.6 OAG23230.1 - 0.038 14.0 0.1 17 5.5 0.0 4.3 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Ribonuc_red_sm PF00268.21 OAG23231.1 - 3.6e-122 407.2 0.4 4.5e-122 406.9 0.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HATPase_c PF02518.26 OAG23233.1 - 1.3e-21 77.1 0.2 5e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG23233.1 - 5e-17 62.1 0.0 1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG23233.1 - 4.1e-08 33.2 0.1 2.3e-07 30.8 0.1 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAG23233.1 - 0.00028 21.1 0.0 13 6.1 0.0 4.2 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 OAG23233.1 - 0.0025 18.1 0.1 2.2 8.6 0.0 3.1 2 1 0 2 2 2 2 PAS fold GAF_2 PF13185.6 OAG23233.1 - 0.007 16.7 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 OAG23233.1 - 0.021 14.8 0.0 12 5.9 0.0 4.2 4 0 0 4 4 4 0 PAS fold Hormone_1 PF00103.20 OAG23233.1 - 0.037 13.8 1.2 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 Somatotropin hormone family HATPase_c_3 PF13589.6 OAG23233.1 - 0.042 13.7 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 OAG23233.1 - 0.054 13.8 0.0 3.1 8.1 0.0 3.0 2 0 0 2 2 2 0 PAS domain DivIC PF04977.15 OAG23233.1 - 0.75 9.6 3.0 2.2 8.1 3.0 1.8 1 0 0 1 1 1 0 Septum formation initiator RNA_pol_Rpc4 PF05132.14 OAG23234.1 - 1.4e-29 103.4 0.1 1.4e-29 103.4 0.1 5.2 3 2 1 4 4 4 1 RNA polymerase III RPC4 Arm PF00514.23 OAG23235.1 - 2e-74 243.6 32.1 6.5e-13 48.2 0.2 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG23235.1 - 2.3e-19 69.5 15.3 5.6e-06 26.7 0.3 8.2 6 2 3 9 9 9 6 HEAT-like repeat HEAT_2 PF13646.6 OAG23235.1 - 3.7e-19 68.9 10.2 3.6e-05 24.1 0.1 7.2 3 3 4 8 8 8 6 HEAT repeats HEAT PF02985.22 OAG23235.1 - 7e-17 60.1 14.2 0.083 13.2 0.0 9.3 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 OAG23235.1 - 3e-13 49.2 7.5 2.2e-08 33.1 1.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 OAG23235.1 - 1e-11 43.8 0.3 1e-11 43.8 0.3 1.6 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 OAG23235.1 - 6.8e-11 42.1 5.4 1.2e-06 28.1 1.9 2.5 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 OAG23235.1 - 1.3e-08 34.5 1.7 1.8e-05 24.2 0.5 3.5 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 OAG23235.1 - 8.5e-07 29.2 7.2 0.0097 16.0 0.3 5.4 2 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAG23235.1 - 0.00012 22.1 10.7 0.28 11.1 0.1 4.5 2 1 4 6 6 6 3 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 OAG23235.1 - 0.0034 17.5 4.1 7.8 6.7 0.0 5.0 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 OAG23235.1 - 0.0054 16.7 7.1 1.1 9.3 0.4 4.9 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 OAG23235.1 - 0.0074 15.4 4.0 3.9 6.5 0.1 4.3 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) DAP_B PF07930.12 OAG23235.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 D-aminopeptidase, domain B HEAT_PBS PF03130.16 OAG23235.1 - 0.013 16.1 9.1 10 7.1 0.8 6.6 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 OAG23235.1 - 0.023 13.2 3.2 0.59 8.6 0.3 3.2 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit UNC45-central PF11701.8 OAG23235.1 - 0.043 13.8 2.7 8.9 6.3 0.2 3.6 3 2 1 4 4 4 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 OAG23235.1 - 0.097 13.3 0.0 6 7.5 0.0 3.3 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region YqfD PF06898.11 OAG23235.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Vpu PF00558.19 OAG23235.1 - 0.24 11.2 2.4 0.26 11.1 0.6 1.9 2 0 0 2 2 2 0 Vpu protein Pkinase PF00069.25 OAG23236.1 - 7.5e-44 150.1 0.0 9.6e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23236.1 - 3.4e-26 92.1 0.0 1.6e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase CLN3 PF02487.17 OAG23236.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 CLN3 protein Kinase-like PF14531.6 OAG23236.1 - 0.036 13.4 0.6 0.16 11.3 0.0 2.2 3 0 0 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 OAG23236.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF5127 PF17168.4 OAG23237.1 - 6.5e-83 278.0 1.6 9.6e-83 277.4 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 OAG23237.1 - 2.1e-76 255.4 0.3 4.3e-76 254.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAG23237.1 - 8.2e-66 221.5 0.0 2.2e-65 220.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 OAG23237.1 - 0.019 14.4 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term FMP23 PF17315.2 OAG23237.1 - 0.029 14.6 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Found in mitochondrial proteome Meckelin PF09773.9 OAG23238.1 - 0.31 9.1 1.0 0.38 8.8 1.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF1749 PF08538.10 OAG23239.1 - 1.7e-47 162.0 0.0 2e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Sugar_tr PF00083.24 OAG23241.1 - 3.5e-80 270.1 14.4 4e-80 269.9 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG23241.1 - 2.2e-30 105.8 38.1 3.4e-29 101.9 16.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG23241.1 - 4.8e-08 32.0 12.7 6.1e-05 21.8 0.1 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 OAG23241.1 - 6.5e-07 28.2 6.1 2.9e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAG23241.1 - 0.0071 15.2 5.9 0.1 11.5 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 OAG23241.1 - 0.55 8.4 13.9 0.26 9.5 0.8 3.4 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.21 OAG23241.1 - 1.3 8.3 6.6 0.095 12.0 0.6 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF5009 PF16401.5 OAG23242.1 - 0.022 14.3 0.7 0.037 13.5 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5009) Zn_clus PF00172.18 OAG23243.1 - 1.3e-08 34.8 11.6 2.4e-08 34.0 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG23243.1 - 6e-07 28.6 0.1 9.1e-07 28.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG23244.1 - 5e-31 107.7 0.2 7.1e-31 107.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23244.1 - 1.2e-24 87.1 0.1 2.4e-24 86.2 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23244.1 - 3.3e-19 69.5 0.0 4.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG23244.1 - 9.8e-08 31.7 0.0 2.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG23244.1 - 0.00027 20.2 0.0 0.00031 20.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG23244.1 - 0.0053 16.3 0.2 0.0084 15.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family ThiF PF00899.21 OAG23244.1 - 0.049 13.0 0.3 0.51 9.6 0.1 2.3 3 0 0 3 3 3 0 ThiF family RmlD_sub_bind PF04321.17 OAG23244.1 - 0.062 12.4 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG23244.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase QSregVF_b PF12843.7 OAG23246.1 - 0.079 12.9 0.0 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor RE_Eco29kI PF09517.10 OAG23246.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Eco29kI restriction endonuclease KRE1 PF17056.5 OAG23251.1 - 0.00015 21.4 5.4 0.0034 17.1 1.2 3.1 3 0 0 3 3 3 2 Killer toxin-resistance protein 1 Glyco_hydro_16 PF00722.21 OAG23253.1 - 6.7e-19 68.0 0.2 1.1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 OAG23253.1 - 0.024 14.7 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) RasGEF PF00617.19 OAG23255.1 - 8.5e-61 205.2 0.3 1.7e-60 204.3 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG23255.1 - 6.5e-29 100.3 0.0 1.5e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAG23255.1 - 3.1e-15 55.5 0.1 6.5e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG23255.1 - 2.5e-14 52.9 0.1 5.7e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG23255.1 - 5.3e-12 45.2 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAG23255.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF4210 PF13915.6 OAG23256.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4210) Fungal_trans PF04082.18 OAG23257.1 - 3.7e-16 59.0 2.6 5.4e-16 58.4 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_3rep PF18868.1 OAG23257.1 - 0.062 14.0 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 OAG23257.1 - 0.18 12.3 0.8 0.59 10.7 0.8 1.9 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.26 OAG23257.1 - 0.41 11.2 1.6 1.3 9.6 1.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_L7Ae PF01248.26 OAG23258.1 - 1e-20 73.3 2.8 7.8e-20 70.4 2.8 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family VWA_2 PF13519.6 OAG23258.1 - 0.061 14.0 0.0 0.098 13.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyco_hydro_61 PF03443.14 OAG23259.1 - 3.7e-58 196.9 0.1 4.2e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 OAG23259.1 - 0.00067 19.5 0.0 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain vWA-TerF-like PF10138.9 OAG23260.1 - 4.7e-07 30.1 0.0 5.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OAG23260.1 - 0.0095 16.2 0.2 0.014 15.7 0.2 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain GhoS PF11080.8 OAG23260.1 - 0.14 12.2 0.1 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Endoribonuclease GhoS MtrD PF04207.12 OAG23262.1 - 0.00064 19.5 0.2 0.00064 19.5 0.2 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D Trp_Tyr_perm PF03222.13 OAG23262.1 - 0.66 9.0 2.8 0.78 8.7 2.8 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family PGP_phosphatase PF09419.10 OAG23263.1 - 5.4e-69 231.1 0.0 6.3e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAG23263.1 - 1.1e-05 25.4 0.1 1.8e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like LSM PF01423.22 OAG23264.1 - 1.5e-15 56.6 0.3 1.8e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_S21e PF01249.18 OAG23264.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S21e Adaptin_binding PF10199.9 OAG23265.1 - 6.3e-13 49.4 3.8 1.5e-12 48.2 3.8 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Methyltransf_23 PF13489.6 OAG23266.1 - 5.4e-16 58.9 0.0 7.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG23266.1 - 6.5e-15 55.7 0.0 1.3e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG23266.1 - 1.4e-14 54.5 0.0 2.1e-12 47.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG23266.1 - 2.1e-14 53.6 0.0 2.9e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG23266.1 - 4.7e-14 52.8 0.0 3.1e-13 50.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG23266.1 - 0.0021 18.1 0.0 0.0038 17.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAG23266.1 - 0.0039 16.8 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OAG23266.1 - 0.0044 16.4 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG23266.1 - 0.013 15.1 0.0 0.058 12.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG23266.1 - 0.018 14.5 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 OAG23266.1 - 0.023 13.7 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 OAG23266.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme TehB PF03848.14 OAG23266.1 - 0.025 14.0 0.0 0.69 9.3 0.0 2.2 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 OAG23266.1 - 0.03 15.3 0.0 0.06 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OAG23266.1 - 0.031 14.1 0.0 0.79 9.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 OAG23266.1 - 0.037 13.8 0.1 0.12 12.1 0.0 1.8 2 1 0 2 2 2 0 Lysine methyltransferase PrmA PF06325.13 OAG23266.1 - 0.085 12.2 0.0 0.33 10.3 0.0 1.9 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OAG23266.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SprT-like PF10263.9 OAG23267.1 - 3.6e-09 36.5 0.0 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 SprT-like family PNISR PF15996.5 OAG23267.1 - 4.9 7.4 9.9 9.4 6.5 9.9 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Mpv17_PMP22 PF04117.12 OAG23268.1 - 4.2e-12 46.1 3.6 2.7e-11 43.5 2.8 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.15 OAG23268.1 - 0.14 11.1 2.1 0.2 10.5 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NADH_oxidored PF08040.11 OAG23268.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit Vasculin PF15337.6 OAG23269.1 - 0.098 13.5 0.9 0.32 11.8 0.1 2.2 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Peptidase_M16_C PF05193.21 OAG23270.1 - 6.1e-54 182.8 0.0 1.5e-53 181.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG23270.1 - 1.1e-39 135.8 0.0 4.5e-39 133.8 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.11 OAG23270.1 - 0.057 13.5 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Disulphide isomerase TRPM_tetra PF16519.5 OAG23270.1 - 1.4 9.1 4.0 14 5.8 0.6 2.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM FHA PF00498.26 OAG23271.1 - 3.6e-16 59.3 0.0 6.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 OAG23271.1 - 7.9e-13 47.9 6.6 1.4e-12 47.1 6.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAG23271.1 - 4.5e-07 30.1 8.8 8.3e-07 29.3 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 OAG23271.1 - 5.5e-05 23.4 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 OAG23271.1 - 0.0042 16.9 8.4 0.0078 16.0 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG23271.1 - 0.0069 16.2 7.6 0.012 15.5 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG23271.1 - 0.0088 16.1 1.8 0.015 15.3 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 OAG23271.1 - 0.016 15.1 4.1 0.03 14.2 4.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 OAG23271.1 - 0.025 14.5 4.8 0.042 13.8 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF2956 PF11169.8 OAG23271.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) zf-rbx1 PF12678.7 OAG23271.1 - 0.13 12.5 9.2 0.42 10.9 9.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG23271.1 - 0.42 10.7 7.9 0.88 9.7 7.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAG23271.1 - 3.2 7.5 8.9 2.4 7.8 7.0 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Bestrophin PF01062.21 OAG23272.1 - 2.4e-55 188.0 0.0 1.6e-54 185.3 0.0 1.8 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PEX11 PF05648.14 OAG23273.1 - 0.0023 17.4 2.7 0.76 9.2 0.1 2.9 2 1 1 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Ribonuclease PF00545.20 OAG23274.1 - 2.8e-08 34.4 0.4 3.9e-08 33.9 0.4 1.2 1 0 0 1 1 1 1 ribonuclease PH_17 PF18012.1 OAG23274.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 PH domain Cullin PF00888.22 OAG23275.1 - 1.9e-179 598.3 5.3 2.3e-179 598.0 5.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG23275.1 - 6e-22 77.4 0.2 1.4e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Peptidase_C37 PF05416.12 OAG23276.1 - 6.9 5.1 16.5 0.18 10.3 9.6 1.6 1 1 0 2 2 2 0 Southampton virus-type processing peptidase Dynamin_N PF00350.23 OAG23278.1 - 6.5e-43 146.7 0.0 1.2e-42 145.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG23278.1 - 1.5e-12 47.4 0.2 4.8e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 OAG23278.1 - 1.6e-05 25.0 0.0 5.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG23278.1 - 0.042 14.2 0.9 0.24 11.7 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OAG23278.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG23278.1 - 0.14 11.8 1.1 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain UreD PF01774.17 OAG23279.1 - 8.3e-73 244.8 0.0 9.9e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein NDUF_B8 PF05821.11 OAG23279.1 - 0.038 13.9 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) B-block_TFIIIC PF04182.12 OAG23280.1 - 1.4e-17 63.6 0.0 4.1e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF123 PF01986.16 OAG23280.1 - 0.1 13.1 0.2 0.31 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF123 GMC_oxred_N PF00732.19 OAG23281.1 - 2.5e-63 214.2 0.0 5.1e-61 206.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG23281.1 - 9.5e-25 87.8 0.0 2.3e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG23281.1 - 6.6e-07 28.8 0.9 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG23281.1 - 7.3e-07 29.1 0.3 6.2e-06 26.0 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG23281.1 - 3.1e-05 23.4 0.2 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG23281.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG23281.1 - 0.00034 19.8 0.1 0.011 14.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG23281.1 - 0.0021 17.4 0.4 0.23 10.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG23281.1 - 0.016 15.8 1.6 0.071 13.7 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG23281.1 - 0.038 12.7 0.5 0.2 10.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OAG23281.1 - 0.044 14.1 0.3 0.1 12.9 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAG23281.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.6 OAG23283.1 - 1.7e-15 57.4 0.1 2.5e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG23283.1 - 1.1e-12 48.0 0.1 1.4e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG23283.1 - 3e-05 23.6 0.1 0.001 18.6 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23283.1 - 0.00016 21.3 0.1 0.0026 17.3 0.2 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG23283.1 - 0.045 13.2 0.1 0.077 12.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RE_Bsp6I PF09504.10 OAG23283.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Sec2p PF06428.11 OAG23284.1 - 2.6e-12 46.5 14.2 4.4e-11 42.6 9.7 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4795 PF16043.5 OAG23284.1 - 5.9e-05 22.8 3.5 0.2 11.2 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4795) Jnk-SapK_ap_N PF09744.9 OAG23284.1 - 0.00027 21.2 16.9 0.08 13.2 10.4 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 HR1 PF02185.16 OAG23284.1 - 0.0014 18.7 15.3 0.025 14.7 0.6 2.5 2 0 0 2 2 2 2 Hr1 repeat PDCD7 PF16021.5 OAG23284.1 - 0.014 14.6 12.2 0.069 12.3 8.1 2.1 2 0 0 2 2 2 0 Programmed cell death protein 7 PI3K_P85_iSH2 PF16454.5 OAG23284.1 - 0.033 13.8 7.8 0.057 13.0 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 OAG23284.1 - 0.042 12.7 14.4 0.071 12.0 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein PBECR5 PF18814.1 OAG23284.1 - 0.044 13.7 2.2 0.09 12.7 0.0 2.0 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 TFIID-18kDa PF02269.16 OAG23284.1 - 0.045 13.8 2.9 0.14 12.2 2.9 1.8 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DNA_ligase_ZBD PF03119.16 OAG23284.1 - 0.056 13.5 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain LXG PF04740.12 OAG23284.1 - 0.084 12.6 0.6 9.2 5.9 0.0 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily BST2 PF16716.5 OAG23284.1 - 0.12 12.9 7.0 0.68 10.5 0.7 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF5082 PF16888.5 OAG23284.1 - 0.13 12.5 8.9 0.24 11.7 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 OAG23284.1 - 0.13 11.8 9.9 0.097 12.2 4.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Aminotran_1_2 PF00155.21 OAG23284.1 - 0.15 11.2 0.1 0.15 11.2 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II HSBP1 PF06825.12 OAG23284.1 - 0.18 11.7 7.8 0.23 11.4 0.6 3.4 4 0 0 4 4 3 0 Heat shock factor binding protein 1 DUF4140 PF13600.6 OAG23284.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.2 2 1 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 OAG23284.1 - 0.2 11.8 18.5 1.6 8.8 1.0 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.11 OAG23284.1 - 0.2 11.6 0.7 26 4.8 0.0 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation XkdW PF09636.10 OAG23284.1 - 0.3 11.2 2.1 1.7 8.8 0.1 2.4 1 1 1 2 2 2 0 XkdW protein XhlA PF10779.9 OAG23284.1 - 0.33 11.2 9.2 0.39 11.0 0.3 3.2 2 1 0 2 2 2 0 Haemolysin XhlA zf-C4pol PF14260.6 OAG23284.1 - 0.41 11.1 1.5 0.79 10.2 0.2 2.2 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta YlqD PF11068.8 OAG23284.1 - 0.47 10.8 11.4 0.75 10.2 4.6 2.1 2 0 0 2 2 2 0 YlqD protein FlaC_arch PF05377.11 OAG23284.1 - 0.49 10.8 6.1 6.7 7.2 0.0 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 OAG23284.1 - 0.5 10.7 1.7 7 7.0 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 OAG23284.1 - 0.56 10.3 16.3 0.19 11.8 0.9 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OAG23284.1 - 0.66 10.5 15.6 1.7 9.2 0.0 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 OAG23284.1 - 0.7 10.1 6.1 0.81 9.9 0.3 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OAG23284.1 - 0.75 10.5 14.1 4.5 8.0 1.5 3.4 2 2 0 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 OAG23284.1 - 1 8.9 12.0 3.2 7.2 4.9 2.0 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 OAG23284.1 - 1.3 9.6 6.2 9.8 6.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Fmp27_WPPW PF10359.9 OAG23284.1 - 1.3 7.8 7.9 3.4 6.4 0.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.9 OAG23284.1 - 1.5 9.2 6.6 4 7.8 0.2 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 OAG23284.1 - 1.5 6.6 2.6 19 3.0 1.5 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 OAG23284.1 - 1.6 9.5 5.0 9.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Occludin homology domain Noelin-1 PF12308.8 OAG23284.1 - 1.8 8.6 6.5 0.98 9.4 0.2 2.4 2 1 1 3 3 3 0 Neurogenesis glycoprotein AAA_13 PF13166.6 OAG23284.1 - 2 6.9 6.1 4.8 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Phage_Mu_Gam PF07352.12 OAG23284.1 - 2.2 8.2 8.6 0.86 9.5 1.2 2.3 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein CLZ PF16526.5 OAG23284.1 - 2.6 8.5 18.7 3.2 8.2 7.4 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Csm1_N PF18504.1 OAG23284.1 - 5 7.5 10.6 2.4 8.6 0.5 3.0 2 1 0 3 3 3 0 Csm1 N-terminal domain Swi5 PF07061.11 OAG23284.1 - 5.1 7.3 7.6 4.1 7.6 0.5 2.8 2 1 0 2 2 2 0 Swi5 Osmo_CC PF08946.10 OAG23284.1 - 5.8 7.2 8.3 9.3 6.6 0.8 3.0 2 2 0 2 2 2 0 Osmosensory transporter coiled coil HrpB7 PF09486.10 OAG23284.1 - 6.3 7.2 24.2 0.49 10.8 3.4 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HrpE PF06188.12 OAG23284.1 - 7.3 6.4 10.4 0.39 10.6 4.2 1.8 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E WD40 PF00400.32 OAG23285.1 - 4.6e-05 24.1 0.6 3 8.8 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ABA_WDS PF02496.16 OAG23285.1 - 0.17 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 ABA/WDS induced protein F-box-like_2 PF13013.6 OAG23286.1 - 0.012 15.6 0.2 0.085 12.8 0.0 2.2 2 1 0 2 2 2 0 F-box-like domain OmpH PF03938.14 OAG23286.1 - 0.064 13.6 0.8 0.11 12.8 0.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_M49 PF03571.15 OAG23286.1 - 0.068 11.5 0.1 0.092 11.1 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M49 polyprenyl_synt PF00348.17 OAG23287.1 - 1.4e-64 217.6 0.0 1.7e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CPSF100_C PF13299.6 OAG23288.1 - 0.0077 16.4 0.9 0.0077 16.4 0.9 4.9 3 1 2 5 5 5 1 Cleavage and polyadenylation factor 2 C-terminal OHCU_decarbox PF09349.10 OAG23289.1 - 8.1e-51 172.6 0.2 9.2e-51 172.4 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Mito_carr PF00153.27 OAG23291.1 - 1.6e-52 175.4 4.0 3.1e-18 65.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 OAG23292.1 - 7.6e-15 55.1 4.7 5e-06 27.1 2.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23292.1 - 1.5e-06 28.4 0.0 0.0084 16.4 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Las1 PF04031.13 OAG23293.1 - 8.6e-46 155.8 0.6 8.6e-46 155.8 0.6 1.6 2 0 0 2 2 2 1 Las1-like DUF2859 PF11072.8 OAG23294.1 - 0.13 12.0 1.3 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Acetyltransf_7 PF13508.7 OAG23296.1 - 4.4e-10 39.8 0.0 1.1e-09 38.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG23296.1 - 7e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG23296.1 - 2.4e-09 37.4 0.0 5.2e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG23296.1 - 3.4e-06 27.2 0.0 0.00039 20.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG23296.1 - 0.00097 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG23296.1 - 0.0019 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Fungal_trans_2 PF11951.8 OAG23297.1 - 8.4e-08 31.4 0.1 1.6e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23297.1 - 3.3e-07 30.3 7.1 4.7e-07 29.8 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRiA4_ORF3 PF07929.11 OAG23297.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein RTA1 PF04479.13 OAG23298.1 - 2.3e-63 213.5 10.3 2.3e-63 213.5 10.3 1.8 1 1 1 2 2 2 1 RTA1 like protein DUF4059 PF13268.6 OAG23298.1 - 2.3 8.7 9.1 0.14 12.6 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Mtp PF03821.16 OAG23298.1 - 2.7 7.5 8.5 0.2 11.2 2.4 2.0 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter CCSMST1 PF15013.6 OAG23298.1 - 3.4 7.9 4.9 13 6.0 0.3 2.8 3 0 0 3 3 3 0 CCSMST1 family SecY PF00344.20 OAG23299.1 - 1.5e-71 241.2 10.4 1.8e-71 240.9 10.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAG23299.1 - 1.9e-17 62.8 0.2 5e-17 61.4 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 OAG23299.1 - 0.15 12.1 0.3 14 5.9 0.1 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2929 PF11151.8 OAG23299.1 - 9.5 6.6 9.9 0.16 12.3 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Troponin PF00992.20 OAG23300.1 - 0.0084 16.4 11.7 0.011 16.0 11.7 1.2 1 0 0 1 1 1 1 Troponin JIP_LZII PF16471.5 OAG23300.1 - 0.0092 16.1 10.3 0.023 14.8 3.2 2.3 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II zf-HC5HC2H PF13771.6 OAG23300.1 - 0.016 15.5 3.7 0.024 14.9 3.1 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain TraC PF07820.12 OAG23300.1 - 0.075 13.4 7.5 0.6 10.5 7.5 2.1 1 1 0 1 1 1 0 TraC-like protein APG6_N PF17675.1 OAG23300.1 - 0.094 13.2 18.8 0.13 12.8 18.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 OAG23300.1 - 0.13 10.8 6.0 0.16 10.6 6.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 OAG23300.1 - 0.15 12.4 7.0 0.23 11.8 7.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NRBF2 PF08961.10 OAG23300.1 - 0.38 10.3 11.2 1.3 8.6 11.3 1.7 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Baculo_p24 PF05073.12 OAG23300.1 - 0.44 10.3 4.9 0.63 9.8 4.9 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein ORF6C PF10552.9 OAG23300.1 - 0.86 9.7 10.5 2.6 8.2 3.5 2.6 2 1 1 3 3 3 0 ORF6C domain DUF724 PF05266.14 OAG23300.1 - 1 9.1 11.0 1.4 8.7 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HALZ PF02183.18 OAG23300.1 - 1.9 8.8 12.2 0.16 12.2 2.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 OAG23300.1 - 2.8 7.2 10.2 5.1 6.3 8.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 OAG23300.1 - 3.1 7.6 15.6 0.96 9.3 4.2 2.5 1 1 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 OAG23300.1 - 3.8 7.6 8.6 3.2 7.8 1.1 2.2 1 1 1 2 2 2 0 FlxA-like protein SlyX PF04102.12 OAG23300.1 - 4.3 8.0 10.8 4.9 7.8 2.0 2.4 1 1 1 2 2 2 0 SlyX bZIP_1 PF00170.21 OAG23300.1 - 6.1 7.0 16.7 1.7 8.8 6.8 2.7 1 1 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 OAG23300.1 - 7 7.2 21.6 2.1 8.8 7.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Fungal_TACC PF12709.7 OAG23300.1 - 9 6.8 14.3 16 6.0 3.0 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TetR_C_6 PF13977.6 OAG23301.1 - 0.66 10.2 7.7 2.3 8.5 0.1 2.8 2 2 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF5595 PF18077.1 OAG23301.1 - 4.8 7.3 15.4 0.46 10.6 2.4 3.8 4 2 0 4 4 4 0 Domain of unknown function (DUF5595) AAA_lid_2 PF17863.1 OAG23302.1 - 1e-06 28.5 0.2 2.8e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 OAG23302.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ORC4_C PF14629.6 OAG23302.1 - 0.029 13.7 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus NAD_kinase PF01513.21 OAG23303.1 - 3.1e-73 246.5 0.0 5.1e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAG23303.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain zf-C2H2 PF00096.26 OAG23304.1 - 0.04 14.4 0.1 0.095 13.2 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOLN PF09289.10 OAG23306.1 - 0.13 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain FAD_binding_4 PF01565.23 OAG23307.1 - 3.7e-17 62.4 0.3 7.8e-17 61.3 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG23307.1 - 1.8e-10 40.7 0.0 6.7e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG23307.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Stm1_N PF09598.10 OAG23308.1 - 6.4e-14 52.6 4.5 6.4e-14 52.6 4.5 4.9 4 2 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 OAG23308.1 - 2.6e-06 28.3 6.3 2.6e-06 28.3 6.3 2.6 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family bZIP_1 PF00170.21 OAG23309.1 - 6.1e-06 26.2 7.2 6.1e-06 26.2 7.2 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG23309.1 - 0.0049 16.9 7.1 0.014 15.4 7.1 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Mit_KHE1 PF10173.9 OAG23309.1 - 0.059 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Vir_act_alpha_C PF10400.9 OAG23309.1 - 0.25 12.0 2.9 0.72 10.6 2.9 1.8 1 0 0 1 1 1 0 Virulence activator alpha C-term Fib_alpha PF08702.10 OAG23309.1 - 9.7 6.4 7.7 0.71 10.0 2.8 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Arrestin_C PF02752.22 OAG23310.1 - 1.8e-13 51.1 0.0 4.7e-10 40.0 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG23310.1 - 0.014 15.5 0.2 1.7 8.7 0.0 3.4 2 2 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 OAG23310.1 - 0.03 13.3 0.0 7.6 5.5 0.0 2.5 2 1 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 SMP PF04927.12 OAG23311.1 - 8.4e-08 32.6 7.3 0.31 11.5 0.7 4.2 3 1 1 4 4 4 4 Seed maturation protein COesterase PF00135.28 OAG23313.1 - 2.4e-96 323.6 0.0 2.7e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG23313.1 - 4.3e-08 33.3 0.2 1.2e-07 31.8 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DAO PF01266.24 OAG23314.1 - 3.1e-35 122.4 0.2 3.6e-35 122.2 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG23314.1 - 0.00033 20.0 2.4 0.00033 20.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAG23314.1 - 0.00079 19.6 2.2 0.0011 19.2 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG23314.1 - 0.0017 17.5 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 OAG23314.1 - 0.073 12.4 0.4 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Ribonuc_L-PSP PF01042.21 OAG23315.1 - 1.2e-33 115.7 0.0 1.3e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5363 PF17320.2 OAG23315.1 - 0.022 14.6 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5363) MFS_1 PF07690.16 OAG23316.1 - 9.9e-32 110.2 34.6 1.3e-31 109.8 34.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG23316.1 - 1.8e-06 27.5 19.6 4.9e-06 26.1 9.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Ank_2 PF12796.7 OAG23318.1 - 0.0035 17.9 0.5 5.4 7.7 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23318.1 - 0.015 15.9 0.2 16 6.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG23318.1 - 0.14 12.5 0.3 6.1 7.3 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Hydrophobin_2 PF06766.11 OAG23319.1 - 3.4e-26 91.0 12.7 6.2e-26 90.1 12.7 1.4 1 0 0 1 1 1 1 Fungal hydrophobin AA_permease_2 PF13520.6 OAG23321.1 - 3.7e-53 180.9 29.6 4.5e-53 180.6 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG23321.1 - 2.2e-20 72.7 28.7 4.9e-20 71.6 28.7 1.6 1 1 0 1 1 1 1 Amino acid permease HEAT PF02985.22 OAG23322.1 - 8.5e-41 134.5 16.9 0.016 15.4 0.0 13.3 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 OAG23322.1 - 3.4e-37 126.7 5.7 3e-11 43.5 0.0 8.5 3 3 6 9 9 9 8 HEAT repeats Cnd1 PF12717.7 OAG23322.1 - 1.9e-13 50.8 9.8 0.0039 17.3 0.1 6.2 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG23322.1 - 4e-12 46.6 3.2 0.00033 21.2 0.1 7.3 5 3 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG23322.1 - 7.3e-12 45.5 6.4 0.025 15.1 0.0 8.8 7 3 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.20 OAG23322.1 - 3.4e-08 32.5 2.7 3.2e-07 29.3 0.6 3.2 2 1 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 OAG23322.1 - 4.2e-07 30.1 5.9 0.25 11.6 0.1 4.8 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAG23322.1 - 0.0026 17.4 2.8 0.7 9.4 0.1 4.6 4 2 1 5 5 5 1 CLASP N terminal Arm PF00514.23 OAG23322.1 - 0.0048 16.9 1.3 2.1 8.5 0.0 4.4 6 0 0 6 6 4 1 Armadillo/beta-catenin-like repeat TetR_C_16 PF17920.1 OAG23322.1 - 0.026 14.7 0.4 7.4 6.9 0.0 3.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 OAG23322.1 - 0.057 11.9 3.4 1.9 6.9 0.6 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 OAG23322.1 - 0.2 10.7 2.9 2.6 7.1 0.1 3.3 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 OAG23322.1 - 0.22 10.1 5.7 14 4.3 0.1 4.3 4 1 1 5 5 5 0 Proteasome stabiliser Glutaredoxin PF00462.24 OAG23323.1 - 4.7e-18 65.2 0.0 6.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OAG23323.1 - 0.00056 20.3 0.1 0.0015 19.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 OAG23323.1 - 0.0027 18.1 0.0 0.0032 17.8 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 OAG23323.1 - 0.072 12.9 0.4 0.24 11.2 0.2 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain LMBR1 PF04791.16 OAG23324.1 - 1.9e-121 406.5 2.4 2.3e-121 406.2 2.4 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4177 PF13783.6 OAG23324.1 - 0.15 12.3 1.3 0.27 11.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) Rad4 PF03835.15 OAG23324.1 - 0.23 11.1 1.1 0.56 9.9 1.1 1.6 1 1 0 1 1 1 0 Rad4 transglutaminase-like domain Tannase PF07519.11 OAG23325.1 - 3.8e-103 345.9 0.7 4.5e-103 345.7 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 OAG23325.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG23325.1 - 0.096 11.9 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NRIP1_repr_4 PF15690.5 OAG23327.1 - 0.066 12.5 1.5 0.079 12.3 1.5 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 4 CLTH PF10607.9 OAG23327.1 - 1.1 9.1 4.9 2.4 8.0 4.9 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain tRNA-synt_1 PF00133.22 OAG23328.1 - 2.9e-224 745.8 0.2 1.1e-223 743.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG23328.1 - 1.2e-25 90.2 0.0 3.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG23328.1 - 2.4e-14 52.9 0.0 2.5e-05 23.2 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAG23328.1 - 0.13 11.6 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Sfi1 PF08457.10 OAG23329.1 - 9.4e-176 585.7 100.8 3.9e-174 580.4 92.9 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Hce2 PF14856.6 OAG23330.1 - 1e-16 61.1 0.3 1.3e-16 60.7 0.3 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HAD_2 PF13419.6 OAG23331.1 - 1.3e-21 77.4 0.0 2.5e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG23331.1 - 1.5e-14 54.8 1.0 2.4e-14 54.1 1.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG23331.1 - 1.5e-06 28.2 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAG23331.1 - 1.6e-05 25.4 0.4 3.5e-05 24.3 0.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAG23331.1 - 0.0018 18.4 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase But2 PF09792.9 OAG23332.1 - 5.8e-31 107.8 0.1 9.1e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain zf-P11 PF03854.14 OAG23334.1 - 0.054 13.2 3.1 0.11 12.1 3.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger DUF3535 PF12054.8 OAG23336.1 - 2.4e-117 392.8 0.0 2.9e-116 389.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAG23336.1 - 6e-64 216.0 0.0 1.4e-63 214.7 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG23336.1 - 3.4e-20 72.4 0.0 1.9e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAG23336.1 - 1.3e-14 53.0 15.4 0.0057 16.8 0.3 9.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 OAG23336.1 - 4.1e-06 27.1 10.0 0.0036 17.7 0.2 6.7 7 1 1 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 OAG23336.1 - 4.5e-06 27.2 0.0 0.16 12.6 0.0 4.1 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAG23336.1 - 0.00024 20.7 0.0 0.0056 16.3 0.0 2.7 2 1 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 OAG23336.1 - 0.00029 21.3 26.9 1.1 9.9 0.1 9.6 12 0 0 12 12 11 2 HEAT-like repeat UME PF08064.13 OAG23336.1 - 0.002 18.0 2.5 1 9.3 0.0 5.0 4 1 1 5 5 5 1 UME (NUC010) domain TAF6_C PF07571.13 OAG23336.1 - 0.0028 17.9 0.0 4.5 7.7 0.0 4.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain ResIII PF04851.15 OAG23336.1 - 0.023 14.7 0.0 0.066 13.2 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit vWA-TerF-like PF10138.9 OAG23337.1 - 0.02 15.0 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus Metal_resist PF13801.6 OAG23338.1 - 0.00043 20.5 0.5 0.00043 20.5 0.5 2.3 2 0 0 2 2 2 1 Heavy-metal resistance DUF4869 PF16163.5 OAG23339.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) Ank_2 PF12796.7 OAG23340.1 - 3.6e-09 37.1 0.0 2.6e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23340.1 - 1.2e-08 35.4 0.0 0.00025 21.6 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG23340.1 - 1.1e-07 32.0 0.2 3.2e-06 27.3 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG23340.1 - 1e-06 28.9 0.1 6.4e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAG23340.1 - 3.3e-06 27.0 0.0 0.0006 20.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat TAFII28 PF04719.14 OAG23341.1 - 4.1e-24 84.5 0.0 4.3e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Spt5_N PF11942.8 OAG23341.1 - 0.054 14.5 3.3 0.13 13.2 3.3 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 OAG23341.1 - 2.3 8.6 5.9 4.1 7.9 5.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L4 PF00573.22 OAG23342.1 - 3.7e-40 137.7 0.4 4.8e-40 137.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAG23342.1 - 9.3e-29 99.3 0.5 2.3e-28 98.1 0.5 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.20 OAG23343.1 - 1.1e-27 96.4 0.0 1.3e-24 86.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG23343.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DnaJ PF00226.31 OAG23344.1 - 1.9e-20 72.7 2.1 3.8e-20 71.8 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 OAG23345.1 - 5.2e-11 43.4 0.0 1.1e-10 42.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG23345.1 - 4.9e-05 23.6 0.0 0.00097 19.4 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C48 PF02902.19 OAG23346.1 - 0.0069 16.2 1.0 0.02 14.7 1.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SKIP_SNW PF02731.15 OAG23349.1 - 1.4e-68 229.6 2.7 1.4e-68 229.6 2.7 2.3 2 0 0 2 2 2 1 SKIP/SNW domain DUF5619 PF18505.1 OAG23349.1 - 0.057 13.4 0.8 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5619) Dioxygenase_C PF00775.21 OAG23350.1 - 3.4e-49 166.7 0.0 4.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG23350.1 - 9.7e-26 89.4 0.1 1.6e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG23350.1 - 7.9e-06 26.1 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain YtkA PF13115.6 OAG23350.1 - 0.013 16.1 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 YtkA-like TPP_enzyme_N PF02776.18 OAG23351.1 - 3.2e-32 111.5 0.6 6.7e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG23351.1 - 6.6e-20 71.2 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG23351.1 - 4.7e-11 42.7 0.2 3.4e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CBP_BcsO PF17037.5 OAG23351.1 - 0.061 13.5 1.0 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO DUF4267 PF14087.6 OAG23352.1 - 0.04 14.0 0.4 0.061 13.4 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Fungal_trans PF04082.18 OAG23353.1 - 1.1e-09 37.8 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23353.1 - 8.4e-08 32.2 9.6 1.5e-07 31.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 OAG23355.1 - 8.8e-08 32.1 9.1 1.5e-07 31.4 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 OAG23355.1 - 0.017 14.8 14.2 0.031 13.9 14.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2420 PF10336.9 OAG23355.1 - 0.041 13.9 0.2 0.086 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Opy2 PF09463.10 OAG23355.1 - 2.4 8.6 8.6 0.5 10.7 3.6 2.3 2 0 0 2 2 2 0 Opy2 protein RAP1 PF07218.11 OAG23355.1 - 2.8 6.1 7.3 6 5.0 6.1 1.8 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 OAG23355.1 - 9.7 4.1 7.4 14 3.7 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_pp85 PF04637.12 OAG23355.1 - 9.8 4.5 8.4 15 3.9 8.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RTA1 PF04479.13 OAG23356.1 - 5.1e-63 212.4 11.9 5.1e-63 212.4 11.9 2.0 1 1 1 2 2 2 1 RTA1 like protein DUF1980 PF09323.10 OAG23356.1 - 0.01 15.7 2.2 0.01 15.7 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Pro_CA PF00484.19 OAG23357.1 - 4.4e-50 170.0 0.0 6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF3253 PF11625.8 OAG23358.1 - 6.6e-27 93.6 1.0 7.7e-27 93.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) HSCB_C PF07743.13 OAG23359.1 - 1.3 9.6 5.3 1 9.9 1.5 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Apolipoprotein PF01442.18 OAG23360.1 - 0.00052 19.9 9.4 0.00065 19.6 9.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SHE3 PF17078.5 OAG23360.1 - 0.00073 19.3 1.4 0.00082 19.2 1.4 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF883 PF05957.13 OAG23360.1 - 0.022 15.4 17.0 0.45 11.1 6.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF5427 PF10310.9 OAG23360.1 - 0.03 13.3 5.7 0.037 13.0 5.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ApoO PF09769.9 OAG23360.1 - 0.038 14.0 2.0 0.055 13.4 1.1 1.6 1 1 1 2 2 2 0 Apolipoprotein O NAD_binding_4 PF07993.12 OAG23360.1 - 0.21 10.7 2.1 0.23 10.6 2.1 1.1 1 0 0 1 1 1 0 Male sterility protein DUF4449 PF14613.6 OAG23360.1 - 0.59 10.2 9.9 0.91 9.6 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) TP53IP5 PF15331.6 OAG23360.1 - 1 9.5 3.3 1.4 9.1 3.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SCAB_CC PF16712.5 OAG23360.1 - 4.2 7.2 9.8 5.2 6.9 9.5 1.4 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein CDT1_C PF16679.5 OAG23361.1 - 3.7e-20 72.1 0.0 9.5e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain ATP-cone PF03477.16 OAG23361.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 ATP cone domain AT_hook PF02178.19 OAG23361.1 - 0.11 12.5 4.8 0.35 10.9 4.8 1.9 1 0 0 1 1 1 0 AT hook motif LysM PF01476.20 OAG23362.1 - 8.8e-10 38.5 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain SnoaL_2 PF12680.7 OAG23363.1 - 0.0011 19.6 0.1 0.0014 19.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG23363.1 - 0.0031 17.9 0.1 0.0037 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OAG23363.1 - 0.064 13.4 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain Glyco_tranf_2_3 PF13641.6 OAG23364.1 - 2.1e-24 86.7 0.0 3.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG23364.1 - 4.2e-10 39.9 10.6 3.9e-09 36.7 0.8 2.2 2 0 0 2 2 2 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG23364.1 - 0.00093 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG23364.1 - 0.0024 17.4 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 PHO4 PF01384.20 OAG23364.1 - 0.18 10.8 0.4 1.1 8.3 0.5 1.9 2 0 0 2 2 2 0 Phosphate transporter family PTS_2-RNA PF01885.16 OAG23365.1 - 1e-41 143.0 0.0 1.3e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ras PF00071.22 OAG23366.1 - 6.3e-57 191.7 0.0 7.6e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG23366.1 - 1.7e-34 118.6 0.0 2.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG23366.1 - 2.9e-15 56.2 0.0 5.1e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG23366.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG23366.1 - 2.6e-06 27.0 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG23366.1 - 2.4e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG23366.1 - 0.0001 22.7 0.3 0.00016 22.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG23366.1 - 0.00036 20.5 0.1 1.2 9.0 0.0 3.0 2 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 OAG23366.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein zf-C2H2 PF00096.26 OAG23368.1 - 0.013 15.9 3.3 0.038 14.5 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type F-box-like PF12937.7 OAG23370.1 - 0.00074 19.4 0.3 0.0018 18.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG23370.1 - 0.00075 19.3 1.8 0.0013 18.5 0.1 2.3 2 0 0 2 2 2 1 F-box domain Glyco_transf_90 PF05686.12 OAG23371.1 - 9.1e-10 38.0 3.7 2.8e-05 23.2 3.6 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 90 CDO_I PF05995.12 OAG23372.1 - 3.5e-39 133.8 0.0 4.2e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAG23372.1 - 0.0045 16.5 0.0 0.0087 15.5 0.0 1.5 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 OAG23373.1 - 5.3e-41 138.9 0.6 3.3e-40 136.4 0.1 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OAG23373.1 - 2.5e-21 75.9 0.1 8.8e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 OAG23373.1 - 9.2e-20 70.5 0.0 2.6e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OAG23373.1 - 9.4e-10 38.2 0.1 4.5e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG23373.1 - 0.00032 20.8 0.1 0.07 13.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 OAG23373.1 - 0.0012 18.4 0.1 14 5.1 0.0 4.0 2 2 2 4 4 4 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OAG23373.1 - 0.0068 15.4 0.6 0.019 13.9 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OAG23373.1 - 0.043 13.7 0.7 4.7 7.1 0.0 3.2 2 1 1 3 3 3 0 RsgA GTPase AIG1 PF04548.16 OAG23373.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AIG1 family HTH_Tnp_Tc5 PF03221.16 OAG23374.1 - 8.5e-15 54.5 0.3 1.5e-14 53.8 0.3 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OAG23374.1 - 1.3e-07 31.1 0.1 3.5e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 OAG23374.1 - 0.0038 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 OAG23374.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 OAG23374.1 - 0.019 14.9 0.0 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 OAG23374.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease PXA PF02194.15 OAG23375.1 - 1.9e-46 158.4 0.0 3.4e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 PXA domain Med10 PF09748.9 OAG23376.1 - 4.7e-37 126.6 2.1 5.3e-37 126.5 2.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Flagellin_N PF00669.20 OAG23376.1 - 6.5e-05 23.1 0.5 0.00025 21.2 0.3 1.8 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region DUF3877 PF12993.7 OAG23376.1 - 0.001 19.0 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) SSXT PF05030.12 OAG23376.1 - 0.018 14.6 1.2 0.029 14.0 0.4 1.7 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Snapin_Pallidin PF14712.6 OAG23376.1 - 0.027 14.9 0.6 2.4 8.6 0.1 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF5344 PF17279.2 OAG23376.1 - 0.043 14.4 0.5 12 6.5 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) dCache_2 PF08269.11 OAG23376.1 - 0.047 12.9 1.3 0.071 12.3 0.3 1.6 2 0 0 2 2 2 0 Cache domain ImcF-related_N PF14331.6 OAG23376.1 - 0.058 12.8 0.0 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 ImcF-related N-terminal domain TAFH PF07531.14 OAG23376.1 - 0.088 12.9 0.4 6.7 6.9 0.0 2.5 2 1 1 3 3 3 0 NHR1 homology to TAF Elf4 PF07011.11 OAG23376.1 - 0.098 12.6 1.5 1.1 9.2 0.6 2.2 1 1 1 2 2 2 0 Early Flowering 4 domain sCache_2 PF17200.4 OAG23376.1 - 0.1 12.5 2.6 0.2 11.5 0.8 2.0 2 0 0 2 2 2 0 Single Cache domain 2 HCO3_cotransp PF00955.21 OAG23377.1 - 3.4e-74 250.5 11.1 5.4e-41 141.0 8.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 OAG23378.1 - 1.2e-40 139.1 0.0 2.5e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG23378.1 - 1.4e-22 80.2 0.5 1.8e-21 76.6 0.5 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.28 OAG23378.1 - 2.6e-09 37.7 0.0 1.3e-08 35.4 0.0 2.1 1 1 0 1 1 1 1 SET domain ResIII PF04851.15 OAG23378.1 - 0.0003 20.8 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4748 PF15932.5 OAG23378.1 - 0.13 12.1 0.6 0.34 10.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) p450 PF00067.22 OAG23379.1 - 1.4e-61 208.6 0.0 1.9e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-LYAR PF08790.11 OAG23381.1 - 0.24 11.4 0.4 0.77 9.7 0.0 1.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Vac_ImportDeg PF09783.9 OAG23382.1 - 8.7e-32 110.2 0.5 5.5e-20 71.8 0.1 2.3 2 0 0 2 2 2 2 Vacuolar import and degradation protein MLTD_N PF06474.12 OAG23382.1 - 0.11 12.7 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 MltD lipid attachment motif Pyridox_ox_2 PF12900.7 OAG23383.1 - 3.4e-40 137.3 0.0 4.5e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 OAG23383.1 - 0.046 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative FMN-binding domain DUF4734 PF15881.5 OAG23384.1 - 0.24 11.6 2.5 0.66 10.2 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4734) DUF2252 PF10009.9 OAG23384.1 - 1 8.3 7.5 0.74 8.8 6.1 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Aldo_ket_red PF00248.21 OAG23385.1 - 4.6e-60 203.3 0.0 5.7e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 OAG23386.1 - 1.5e-10 42.1 0.0 2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 OAG23387.1 - 8.2e-12 45.6 0.0 5.4e-05 23.7 0.1 4.3 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG23387.1 - 8.8e-06 25.7 3.2 12 6.9 0.0 5.9 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OAG23387.1 - 0.00044 20.5 0.3 3.2 8.2 0.0 4.7 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG23387.1 - 0.0047 17.5 0.0 4.3 8.0 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG23387.1 - 0.0071 16.7 0.1 73 4.1 0.0 4.5 3 1 1 4 4 4 0 Ankyrin repeat DUF3447 PF11929.8 OAG23387.1 - 0.051 13.5 2.9 0.36 10.8 0.1 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OAG23388.1 - 1.2e-09 38.6 1.2 0.00049 20.6 0.0 4.5 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG23388.1 - 6.1e-05 23.1 0.0 3 8.7 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 OAG23388.1 - 0.0035 17.7 0.3 9.4 6.9 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeat Phage_fiber_2 PF03406.13 OAG23388.1 - 0.008 15.7 0.3 0.017 14.7 0.3 1.6 1 0 0 1 1 1 1 Phage tail fibre repeat Ank_2 PF12796.7 OAG23389.1 - 2.7e-11 43.9 0.1 7.3e-06 26.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23389.1 - 5.7e-09 36.4 0.1 0.0001 22.8 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG23389.1 - 1.2e-08 34.5 0.6 0.089 13.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG23389.1 - 0.00048 20.4 0.0 0.01 16.1 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG23389.1 - 0.0012 19.2 0.1 4 8.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_S6 PF01250.17 OAG23390.1 - 1.1e-23 83.4 0.0 1.2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 OAG23391.1 - 2.5e-35 121.0 1.2 3e-35 120.8 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 OAG23391.1 - 0.054 13.5 0.4 0.084 12.8 0.4 1.4 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Glyco_hydro_61 PF03443.14 OAG23392.1 - 8.8e-57 192.4 0.6 1.1e-56 192.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transp_cyt_pur PF02133.15 OAG23393.1 - 3.3e-144 480.9 37.2 3.9e-144 480.7 37.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rick_17kDa_Anti PF05433.15 OAG23394.1 - 0.00048 19.9 13.4 0.0061 16.4 14.6 2.0 1 1 1 2 2 2 2 Glycine zipper 2TM domain TraT PF05818.12 OAG23394.1 - 7.7 6.1 11.4 0.26 11.0 3.5 2.0 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein CoatB PF10389.9 OAG23395.1 - 0.15 11.9 1.9 0.37 10.7 1.9 1.7 1 0 0 1 1 1 0 Bacteriophage coat protein B Syndecan PF01034.20 OAG23395.1 - 0.15 12.0 0.6 0.36 10.8 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain DCP2 PF05026.13 OAG23396.1 - 1.1e-30 105.8 2.5 2.1e-30 104.9 2.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAG23396.1 - 8.9e-16 58.1 0.1 1.6e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 OAG23397.1 - 1.2e-31 109.1 0.6 1.6e-31 108.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Goodbye PF17109.5 OAG23398.1 - 8.4e-08 32.7 0.0 5.1e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 OAG23398.1 - 1.8e-07 31.2 0.1 3.9e-05 23.6 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG23398.1 - 0.00012 22.3 0.3 0.014 15.7 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG23398.1 - 0.00052 20.4 0.0 0.0039 17.6 0.0 2.6 1 0 0 1 1 1 1 AAA ATPase domain ZZ PF00569.17 OAG23398.1 - 0.022 14.5 9.0 0.052 13.4 9.0 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type AAA_32 PF13654.6 OAG23398.1 - 0.05 12.4 0.3 0.98 8.1 0.5 2.3 2 0 0 2 2 2 0 AAA domain LPD39 PF18858.1 OAG23398.1 - 0.06 13.4 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Laminin_II PF06009.12 OAG23398.1 - 0.33 11.0 2.6 0.59 10.1 0.1 2.7 3 0 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 OAG23398.1 - 0.81 9.7 5.2 7.8 6.6 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) PAP2_3 PF14378.6 OAG23400.1 - 4.4e-35 121.1 20.3 3.6e-17 62.7 0.2 3.4 2 1 1 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 OAG23400.1 - 0.0038 17.0 1.6 0.0038 17.0 1.6 2.3 2 1 0 2 2 2 1 PAP2 superfamily CDC14 PF08045.11 OAG23401.1 - 8.2e-119 395.9 0.0 9.3e-119 395.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component F-box PF00646.33 OAG23402.1 - 0.012 15.5 0.1 0.036 13.9 0.1 1.8 1 0 0 1 1 1 0 F-box domain Sod_Cu PF00080.20 OAG23403.1 - 1.5e-08 34.9 0.1 2.3e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fe-ADH PF00465.19 OAG23404.1 - 2.1e-61 207.7 0.0 2.8e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG23404.1 - 1.1e-10 41.7 1.1 9.2e-05 22.3 0.3 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1495 PF07381.11 OAG23404.1 - 0.066 13.1 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) PAN_4 PF14295.6 OAG23406.1 - 0.027 14.4 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 PAN domain PHD PF00628.29 OAG23407.1 - 9e-17 60.7 30.6 1.2e-08 34.7 5.3 3.4 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.6 OAG23407.1 - 2.8e-05 23.6 19.5 0.0091 15.5 1.6 3.5 3 0 0 3 3 3 3 PHD-finger Urb2 PF10441.9 OAG23408.1 - 1.2e-46 159.2 0.1 5.9e-46 157.0 0.0 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family YopH_N PF09013.10 OAG23408.1 - 0.06 13.6 0.2 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 YopH, N-terminal MutL_C PF08676.11 OAG23408.1 - 0.083 12.7 0.8 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 MutL C terminal dimerisation domain Sec7_N PF12783.7 OAG23408.1 - 0.26 11.2 2.7 0.4 10.6 0.5 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF543 PF04418.12 OAG23409.1 - 6.4e-30 103.0 0.0 7.5e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) POT1PC PF16686.5 OAG23411.1 - 5.9e-39 133.4 0.5 1.3e-38 132.4 0.5 1.6 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAG23411.1 - 1.1e-13 51.2 0.0 3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 OAG23411.1 - 0.072 13.1 0.0 7.1 6.7 0.0 2.9 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain NSP16 PF06460.12 OAG23411.1 - 0.16 11.0 0.1 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 Coronavirus NSP16 Nop53 PF07767.11 OAG23411.1 - 0.33 10.3 14.7 0.53 9.6 14.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Arm PF00514.23 OAG23412.1 - 3.4e-97 315.9 14.0 1.5e-13 50.2 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAG23412.1 - 1.4e-26 92.8 1.7 3.9e-26 91.3 1.7 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OAG23412.1 - 6.9e-23 80.0 3.2 1.6e-22 78.8 3.2 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 OAG23412.1 - 6.6e-22 77.6 7.0 1.8e-08 34.7 0.1 6.6 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 OAG23412.1 - 6.5e-20 71.3 2.8 2.4e-09 37.5 0.1 5.7 2 1 4 6 6 6 3 HEAT repeats HEAT PF02985.22 OAG23412.1 - 7.7e-19 66.2 1.8 1.8e-05 24.6 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 OAG23412.1 - 7.1e-09 35.5 0.0 0.042 13.3 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 OAG23412.1 - 2.9e-06 26.1 0.0 8e-05 21.4 0.0 2.5 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 OAG23412.1 - 2.5e-05 24.4 0.0 1.6 8.9 0.0 4.7 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 OAG23412.1 - 0.00021 21.6 2.0 0.66 10.8 0.3 4.9 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OAG23412.1 - 0.00053 20.1 0.0 0.92 9.5 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 OAG23412.1 - 0.0073 15.9 0.0 16 5.0 0.0 3.9 1 1 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 OAG23412.1 - 0.021 15.1 5.8 2.4 8.4 0.1 5.0 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 OAG23412.1 - 0.034 14.0 0.0 33 4.4 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain GATase_4 PF13230.6 OAG23413.1 - 1.6e-16 60.0 0.0 1.9e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAG23413.1 - 6e-09 36.2 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain HET PF06985.11 OAG23414.1 - 1.9e-28 99.7 0.3 3e-28 99.0 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UQ_con PF00179.26 OAG23417.1 - 1.1e-39 135.3 0.0 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG23417.1 - 0.029 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 OAG23417.1 - 0.067 12.8 0.2 0.16 11.6 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RNase_PH PF01138.21 OAG23418.1 - 5.3e-11 43.1 0.1 8.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF908 PF06012.12 OAG23420.1 - 0.097 12.1 2.6 0.14 11.6 2.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SOG2 PF10428.9 OAG23420.1 - 0.34 10.1 9.1 0.39 9.9 9.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MAP65_ASE1 PF03999.12 OAG23420.1 - 0.79 8.3 2.9 0.95 8.1 2.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SMP_LBD PF17047.5 OAG23421.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4131 PF13567.6 OAG23421.1 - 9.6 5.8 6.2 1.3 8.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) A_deaminase PF00962.22 OAG23423.1 - 5e-22 78.6 0.0 2.1e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase RCC1_2 PF13540.6 OAG23424.1 - 6.8e-13 48.1 18.5 1.4e-07 31.1 0.7 6.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OAG23424.1 - 2.9e-07 31.0 0.1 0.0051 17.4 0.0 3.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAG23424.1 - 0.00014 21.7 0.4 0.00026 20.8 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG23424.1 - 0.0025 17.6 0.1 0.0045 16.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain IF-2B PF01008.17 OAG23425.1 - 5.7e-75 252.1 0.1 7.5e-75 251.7 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family TrkA_C PF02080.21 OAG23425.1 - 0.058 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-C domain Presenilin PF01080.17 OAG23425.1 - 7.5 5.2 7.0 11 4.6 7.0 1.2 1 0 0 1 1 1 0 Presenilin tRNA-synt_2 PF00152.20 OAG23426.1 - 8.8e-28 97.3 0.0 1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF3085 PF11284.8 OAG23426.1 - 0.16 12.3 0.1 0.37 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) HAGH_C PF16123.5 OAG23427.1 - 1.5e-21 76.7 0.1 2.6e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAG23427.1 - 1.2e-16 61.4 2.5 1e-14 55.0 2.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pox_P4B PF03292.14 OAG23427.1 - 0.039 12.3 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein GCV_T PF01571.21 OAG23428.1 - 4.1e-70 236.1 0.0 1.5e-69 234.2 0.0 1.8 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OAG23428.1 - 1.3e-45 156.5 0.2 2.2e-45 155.7 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 OAG23428.1 - 1.5e-19 69.7 0.1 3.8e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 OAG23428.1 - 4.5e-16 58.9 0.0 8.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 OAG23428.1 - 2.1e-07 30.5 0.7 0.017 14.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG23428.1 - 9e-07 29.4 0.2 0.011 16.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG23428.1 - 3.2e-05 23.0 0.2 0.00023 20.1 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG23428.1 - 0.00064 19.7 0.4 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG23428.1 - 0.0011 19.2 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 OAG23428.1 - 0.0059 15.9 0.4 0.035 13.4 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.21 OAG23428.1 - 0.0093 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAG23428.1 - 0.012 15.7 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 OAG23428.1 - 0.045 13.0 0.3 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG23428.1 - 0.062 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG23428.1 - 0.064 12.3 0.2 1.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG23428.1 - 0.092 11.8 0.3 0.28 10.2 0.3 1.8 1 1 0 1 1 1 0 FAD binding domain Pectate_lyase PF03211.13 OAG23428.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Pectate lyase Ring_hydroxyl_A PF00848.19 OAG23429.1 - 8.4e-21 74.9 3.1 1.6e-17 64.2 3.1 2.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG23429.1 - 3.3e-16 59.0 0.0 6.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Hydrolase PF00702.26 OAG23430.1 - 2.5e-07 31.2 0.0 1.2e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG23430.1 - 3.8e-06 27.1 0.0 1.1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 OAG23432.1 - 4.6e-59 200.2 0.0 5.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG23432.1 - 4e-36 124.7 0.1 6.2e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 OAG23432.1 - 1.2e-06 27.9 0.0 8.6e-05 21.9 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG23432.1 - 2.7e-05 23.9 0.0 0.0023 17.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG23432.1 - 3.5e-05 23.2 0.0 8.7e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG23432.1 - 8.6e-05 21.8 0.4 0.0012 18.1 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG23432.1 - 0.00024 20.3 0.1 0.00038 19.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG23432.1 - 0.00062 19.9 0.4 0.0023 18.1 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG23432.1 - 0.0016 17.7 0.1 0.18 11.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG23432.1 - 0.068 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAG23432.1 - 0.079 13.0 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG23432.1 - 0.11 11.2 0.1 0.2 10.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAG23432.1 - 0.16 11.1 0.1 1.8 7.6 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG23432.1 - 0.2 10.5 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase p450 PF00067.22 OAG23433.1 - 7.3e-62 209.6 0.0 9.6e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 OAG23435.1 - 5.6e-44 150.7 0.0 8.2e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG23435.1 - 1.8e-29 103.1 0.6 3.7e-29 102.1 0.6 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG23435.1 - 2.3e-05 24.1 0.6 0.0015 18.2 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG23435.1 - 0.00042 19.5 0.0 0.076 12.1 0.2 2.5 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAG23435.1 - 0.001 18.2 0.1 0.0028 16.8 0.1 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG23435.1 - 0.0011 19.2 0.3 0.0049 17.1 0.3 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG23435.1 - 0.0072 15.6 0.1 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 OAG23435.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAG23435.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MRC1 PF09444.10 OAG23436.1 - 2.3 8.7 6.8 0.2 12.1 1.0 2.0 2 0 0 2 2 2 0 MRC1-like domain WD40 PF00400.32 OAG23437.1 - 2.8e-16 59.6 7.8 0.0095 16.8 0.2 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23437.1 - 1.8e-08 34.6 0.1 0.0014 18.8 0.0 4.7 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG23437.1 - 0.0076 15.6 0.0 0.069 12.5 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain S1 PF00575.23 OAG23438.1 - 6.4e-63 209.1 26.8 1.6e-11 44.4 2.0 13.3 13 0 0 13 13 13 8 S1 RNA binding domain RNase_II_C_S1 PF18614.1 OAG23438.1 - 3.4e-07 30.1 1.4 0.035 14.1 0.2 6.0 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain Suf PF05843.14 OAG23438.1 - 4.7e-05 23.5 9.6 0.00015 21.9 0.0 4.1 2 1 1 4 4 4 2 Suppressor of forked protein (Suf) SesA PF17107.5 OAG23438.1 - 0.0041 17.3 1.1 1.8 8.7 0.4 2.6 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_19 PF14559.6 OAG23438.1 - 0.0043 17.5 0.4 0.48 11.0 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat PPR PF01535.20 OAG23438.1 - 0.007 16.5 0.3 0.23 11.8 0.1 3.0 2 0 0 2 2 2 1 PPR repeat Mad3_BUB1_I PF08311.12 OAG23438.1 - 0.0094 15.9 0.1 0.31 11.0 0.1 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 OAG23438.1 - 0.018 15.8 1.0 3.8 8.6 0.2 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAG23438.1 - 0.022 14.0 1.6 1.6 7.8 0.8 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 OAG23438.1 - 0.031 14.5 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 PPR repeat family NRDE-2 PF08424.10 OAG23438.1 - 0.047 12.8 1.7 2.3 7.3 1.8 2.8 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference S1_2 PF13509.6 OAG23438.1 - 0.078 13.0 0.3 3.9 7.6 0.0 3.6 2 0 0 2 2 2 0 S1 domain EXOSC1 PF10447.9 OAG23438.1 - 8.1 7.1 11.2 3.4 8.3 0.1 5.4 5 2 0 5 5 5 0 Exosome component EXOSC1/CSL4 HET PF06985.11 OAG23439.1 - 1.4e-30 106.6 2.4 2.4e-30 105.8 2.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Colicin_D PF11429.8 OAG23439.1 - 0.08 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Colicin D AAA PF00004.29 OAG23440.1 - 4.9e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG23440.1 - 0.0017 18.7 0.0 0.0091 16.4 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG23440.1 - 0.0058 16.9 0.2 0.029 14.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG23440.1 - 0.0076 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 OAG23440.1 - 0.014 15.6 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 OAG23440.1 - 0.023 14.4 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 OAG23440.1 - 0.032 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.6 OAG23440.1 - 0.072 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF2852 PF11014.8 OAG23440.1 - 0.077 13.2 0.2 2.3 8.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DHHW PF14286.6 OAG23441.1 - 0.073 12.4 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 DHHW protein AAA PF00004.29 OAG23442.1 - 1.4e-07 32.0 0.0 2e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG23442.1 - 1.9e-07 31.2 0.1 5.6e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 OAG23442.1 - 0.0012 19.2 0.0 0.004 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG23442.1 - 0.0082 16.7 0.0 0.028 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG23442.1 - 0.025 14.9 0.1 0.51 10.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG23442.1 - 0.042 13.4 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG23442.1 - 0.085 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OAG23442.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG23442.1 - 0.16 12.3 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 OAG23442.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Brucella_OMP2 PF05244.11 OAG23442.1 - 0.28 10.5 1.0 0.9 8.9 0.0 2.0 2 0 0 2 2 2 0 Brucella outer membrane protein 2 Utp8 PF10395.9 OAG23443.1 - 2.4e-10 39.6 2.2 1.7e-08 33.5 0.2 3.4 3 1 0 3 3 3 2 Utp8 family ArAE_2_N PF10337.9 OAG23444.1 - 1.8e-44 152.6 20.8 5.1e-33 114.8 0.0 5.0 4 1 1 5 5 5 4 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAG23444.1 - 5.2e-16 58.9 16.7 5.2e-16 58.9 16.7 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG23444.1 - 5.7e-12 46.0 0.0 6e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 OAG23444.1 - 0.58 10.3 19.6 0.019 15.1 8.3 2.6 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 CytB6-F_Fe-S PF08802.10 OAG23444.1 - 0.72 9.9 4.5 1.1 9.4 0.0 3.4 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit PX PF00787.24 OAG23445.1 - 2.4e-16 59.7 0.1 5.8e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 PX domain V-SNARE_C PF12352.8 OAG23445.1 - 0.00075 19.7 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prefoldin_3 PF13758.6 OAG23445.1 - 0.0096 16.0 1.4 0.025 14.6 0.1 2.3 2 0 0 2 2 2 1 Prefoldin subunit Tmemb_cc2 PF10267.9 OAG23445.1 - 0.04 13.1 1.6 0.085 12.0 1.6 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ndc1_Nup PF09531.10 OAG23445.1 - 1.1 7.8 4.2 2 7.0 4.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PalH PF08733.10 OAG23446.1 - 1.1e-113 379.6 0.0 1.4e-113 379.3 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 zf_CCCH_4 PF18345.1 OAG23447.1 - 3.4e-05 23.7 11.9 0.0028 17.6 4.9 2.8 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OAG23447.1 - 0.0029 18.3 3.1 0.94 10.2 0.1 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 OAG23447.1 - 0.035 13.9 7.8 1.7 8.5 1.8 2.8 2 0 0 2 2 2 0 CCCH-type zinc finger Zn_Tnp_IS91 PF14319.6 OAG23447.1 - 0.31 11.1 10.8 1.1 9.3 6.6 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain IBR PF01485.21 OAG23447.1 - 3.6 7.9 19.5 92 3.4 19.5 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4211 PF13926.6 OAG23448.1 - 2.6e-40 137.8 0.5 7.2e-40 136.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Alb1 PF09135.11 OAG23449.1 - 1.1e-25 90.5 17.7 1.1e-25 90.5 17.7 2.0 1 1 1 2 2 2 1 Alb1 SOAR PF16533.5 OAG23449.1 - 0.48 10.4 7.6 1.1 9.3 7.6 1.7 1 1 0 1 1 1 0 STIM1 Orai1-activating region UCH PF00443.29 OAG23450.1 - 6.1e-36 124.2 0.0 1.1e-35 123.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG23450.1 - 1.4e-06 28.2 0.9 5e-06 26.3 0.9 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S14 PF00253.21 OAG23452.1 - 4.5e-15 55.2 2.4 4.8e-15 55.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e STAG PF08514.11 OAG23453.1 - 8.5e-32 109.4 0.0 8.5e-32 109.4 0.0 3.4 3 0 0 3 3 3 1 STAG domain HEAT PF02985.22 OAG23453.1 - 0.00031 20.8 0.2 5 7.7 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat NinB PF05772.12 OAG23453.1 - 0.066 13.0 0.1 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 NinB protein Cohesin_HEAT PF12765.7 OAG23453.1 - 0.67 10.3 3.2 5.8 7.3 0.2 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ACOX PF01756.19 OAG23453.1 - 0.7 9.4 3.7 23 4.5 0.1 3.7 3 0 0 3 3 3 0 Acyl-CoA oxidase Trns_repr_metal PF02583.17 OAG23453.1 - 1.5 9.2 4.8 2.9 8.3 0.1 3.3 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor CRAL_TRIO PF00650.20 OAG23454.1 - 3e-36 124.5 0.0 3.9e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG23454.1 - 2e-15 56.7 0.1 3.8e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG23454.1 - 4e-05 23.8 0.0 6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 OAG23454.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Pol_alpha_B_N PF08418.10 OAG23455.1 - 3.3e-71 240.1 0.0 5e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 OAG23455.1 - 2.3e-36 125.1 0.2 5.1e-36 124.0 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MRNIP PF15749.5 OAG23455.1 - 0.11 13.3 0.1 0.31 11.8 0.0 1.7 2 0 0 2 2 2 0 MRN-interacting protein Ribosomal_L32e PF01655.18 OAG23457.1 - 1.7e-47 160.3 2.8 2e-47 160.1 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L32 Cullin_binding PF03556.15 OAG23457.1 - 6.5e-32 110.5 7.8 1e-31 109.8 7.8 1.3 1 0 0 1 1 1 1 Cullin binding Spc29 PF17082.5 OAG23460.1 - 0.00039 20.3 1.3 3.2 7.5 0.0 3.5 3 0 0 3 3 3 2 Spindle Pole Component 29 Cep57_CLD PF14073.6 OAG23460.1 - 0.0026 17.8 13.6 0.018 15.1 2.5 2.9 3 0 0 3 3 3 2 Centrosome localisation domain of Cep57 DUF16 PF01519.16 OAG23460.1 - 0.013 16.0 2.8 5.5 7.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 OAG23460.1 - 0.018 15.0 8.7 0.57 10.2 0.1 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RIC3 PF15361.6 OAG23460.1 - 0.06 13.7 0.4 0.21 12.0 0.4 2.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 PKcGMP_CC PF16808.5 OAG23460.1 - 6.7 6.7 7.7 1.9 8.4 0.4 3.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Mpv17_PMP22 PF04117.12 OAG23461.1 - 0.0094 16.2 5.1 0.014 15.6 2.6 2.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family Rubrerythrin PF02915.17 OAG23461.1 - 0.15 12.4 1.3 0.17 12.3 0.1 1.7 2 0 0 2 2 2 0 Rubrerythrin Rhomboid PF01694.22 OAG23461.1 - 0.6 10.1 7.6 0.14 12.2 4.0 1.7 2 0 0 2 2 2 0 Rhomboid family Ribosomal_L22e PF01776.17 OAG23462.1 - 1.4e-48 163.8 1.1 1.8e-48 163.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Ofd1_CTDD PF10637.9 OAG23462.1 - 0.069 12.5 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term dDENN PF03455.19 OAG23462.1 - 0.13 12.3 0.6 0.55 10.3 0.0 2.3 2 2 1 3 3 3 0 dDENN domain LDB19 PF13002.7 OAG23463.1 - 1.5e-51 174.8 0.3 2.7e-51 174.1 0.3 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 OAG23463.1 - 4e-06 27.0 0.0 9.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 OAG23463.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein F-box-like_2 PF13013.6 OAG23464.1 - 0.1 12.6 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain SQS_PSY PF00494.19 OAG23465.1 - 1.4e-53 182.0 0.0 2.6e-53 181.2 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase DUF3526 PF12040.8 OAG23465.1 - 0.043 14.3 0.1 0.092 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) SNF2_N PF00176.23 OAG23466.1 - 2.5e-70 236.9 0.0 3.3e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAG23466.1 - 6e-20 71.0 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAG23466.1 - 4.2e-16 59.3 0.0 8.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG23466.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAG23466.1 - 0.0002 21.2 9.7 0.00038 20.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG23466.1 - 0.00072 19.3 5.2 0.0016 18.3 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG23466.1 - 0.0012 18.7 7.2 0.0022 17.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG23466.1 - 0.0017 18.6 8.9 0.0039 17.5 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain ERCC3_RAD25_C PF16203.5 OAG23466.1 - 0.0035 16.6 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 OAG23466.1 - 0.027 14.5 7.6 0.058 13.4 7.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OAG23466.1 - 0.066 13.2 7.5 0.21 11.5 7.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain SRR1 PF07985.12 OAG23467.1 - 0.00055 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 SRR1 Mononeg_mRNAcap PF14318.6 OAG23467.1 - 0.068 12.4 1.1 0.11 11.8 1.1 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Fungal_trans_2 PF11951.8 OAG23468.1 - 9.8e-08 31.2 0.6 1.7e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Asp PF00026.23 OAG23469.1 - 3.5e-10 39.8 0.1 5.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease PTP_tm PF18861.1 OAG23469.1 - 0.0009 19.3 1.3 0.002 18.2 1.3 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5385 PF17359.2 OAG23469.1 - 0.021 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2681 PF10883.8 OAG23469.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Phage_HK97_TLTM PF06120.11 OAG23469.1 - 0.086 12.0 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein EphA2_TM PF14575.6 OAG23469.1 - 0.088 13.7 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 OAG23469.1 - 0.093 12.6 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 OAG23469.1 - 0.11 11.9 4.3 0.25 10.8 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ECH_2 PF16113.5 OAG23472.1 - 1.8e-126 422.2 0.0 2.4e-126 421.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAG23472.1 - 5.1e-29 101.3 0.0 1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase GTP_EFTU PF00009.27 OAG23473.1 - 4e-58 196.2 0.2 5.2e-58 195.8 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG23473.1 - 1.3e-26 93.1 0.0 2.5e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG23473.1 - 3e-16 59.6 1.9 7.4e-16 58.3 1.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG23473.1 - 8e-06 25.9 0.1 1.6e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG23473.1 - 0.00086 19.2 0.1 0.0037 17.2 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 OAG23473.1 - 0.0051 16.6 0.2 4.2 7.1 0.0 2.6 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OAG23473.1 - 0.027 14.1 0.5 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Beta_protein PF14350.6 OAG23473.1 - 0.17 11.2 0.2 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 Beta protein Fungal_trans PF04082.18 OAG23474.1 - 9.4e-07 28.1 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG23475.1 - 8.9e-20 71.0 0.2 1.4e-16 60.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23475.1 - 1.4e-11 44.4 0.1 6e-10 39.1 0.1 2.2 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23475.1 - 1.4e-08 34.9 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAG23475.1 - 0.016 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FTR PF01913.18 OAG23475.1 - 0.052 13.5 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase NAD_binding_7 PF13241.6 OAG23475.1 - 0.22 12.0 0.8 0.85 10.1 0.8 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1772 PF08592.11 OAG23476.1 - 8.2e-14 52.1 0.0 1.1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) FAD_binding_4 PF01565.23 OAG23477.1 - 1.7e-23 82.9 1.1 2.8e-23 82.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG23477.1 - 1.5e-05 25.0 0.3 5e-05 23.3 0.3 1.9 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 OAG23477.1 - 0.017 14.9 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase BslA PF17735.1 OAG23477.1 - 0.075 13.0 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Biofilm surface layer A p450 PF00067.22 OAG23478.1 - 7.3e-55 186.5 0.0 1.2e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG23479.1 - 2.7e-45 154.8 59.1 2.7e-45 154.8 59.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG23479.1 - 4.7e-10 38.5 25.6 6.4e-10 38.1 25.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG23479.1 - 3e-09 36.3 4.2 3e-09 36.3 4.2 3.4 3 1 0 4 4 4 2 Sugar (and other) transporter Fungal_trans PF04082.18 OAG23480.1 - 8.7e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_bind PF08675.11 OAG23481.1 - 0.14 12.2 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA binding domain CorA PF01544.18 OAG23482.1 - 2.8e-09 36.7 2.9 5.6e-09 35.7 2.6 1.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein HET PF06985.11 OAG23484.1 - 1.4e-34 119.6 0.2 2.2e-34 118.9 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 OAG23485.1 - 3.7e-15 56.5 0.1 8.4e-15 55.3 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG23485.1 - 0.0011 18.6 0.7 0.72 9.4 0.0 2.9 4 0 0 4 4 4 2 RIO1 family Kdo PF06293.14 OAG23485.1 - 0.052 12.9 0.1 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.21 OAG23486.1 - 9.5e-08 32.2 21.9 1.3e-06 28.5 1.8 5.2 5 0 0 5 5 5 3 IBR domain, a half RING-finger domain YjcB PF15940.5 OAG23487.1 - 0.12 12.6 0.3 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function Glyco_hydro_3_C PF01915.22 OAG23488.1 - 6.7e-54 182.9 0.0 1.2e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG23488.1 - 1.2e-33 116.8 0.0 2.9e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG23488.1 - 1.9e-17 63.1 0.1 3.7e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Forkhead PF00250.18 OAG23489.1 - 8.2e-33 112.5 0.2 1.4e-32 111.8 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG23489.1 - 3.4e-08 33.7 0.1 7.7e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 FHA domain Ndufs5 PF10200.9 OAG23490.1 - 0.0095 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 OAG23490.1 - 0.016 15.6 0.8 0.058 13.8 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 OAG23490.1 - 0.078 13.2 0.9 0.17 12.2 0.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 OAG23490.1 - 0.092 13.1 0.3 0.16 12.4 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) HET PF06985.11 OAG23491.1 - 3.2e-24 86.0 0.0 9e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FERM_N PF09379.10 OAG23492.1 - 0.098 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 FERM N-terminal domain DUF4407 PF14362.6 OAG23492.1 - 0.94 8.8 5.9 1.5 8.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5604 PF18300.1 OAG23493.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5604) Ntox1 PF15500.6 OAG23493.1 - 0.3 11.4 3.6 2.2 8.7 3.3 2.1 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Ank_2 PF12796.7 OAG23494.1 - 4.4e-07 30.4 0.1 0.0025 18.3 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG23494.1 - 1.2e-06 28.3 0.1 0.03 14.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAG23494.1 - 0.0018 18.8 0.1 0.11 13.2 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG23494.1 - 0.017 15.4 0.1 0.29 11.5 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) PGC7_Stella PF15549.6 OAG23494.1 - 0.027 14.5 1.4 0.059 13.4 1.4 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Sulfotransfer_4 PF17784.1 OAG23494.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Sulfotransferase domain AA_permease PF00324.21 OAG23495.1 - 4.7e-118 394.8 47.3 5.7e-118 394.5 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG23495.1 - 3.3e-33 115.2 49.3 4.2e-33 114.8 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.21 OAG23497.1 - 7.1e-43 146.9 0.0 9.7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAG23498.1 - 7.9e-07 28.4 0.2 7.9e-07 28.4 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 OAG23499.1 - 6.1e-48 163.8 0.0 1e-47 163.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG23499.1 - 6.5e-45 153.6 0.0 9.9e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG23499.1 - 1.2e-18 67.0 0.4 2.5e-18 65.9 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG23499.1 - 5.4e-07 29.5 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 OAG23499.1 - 0.021 15.2 0.5 0.059 13.8 0.5 1.8 1 0 0 1 1 1 0 GLEYA domain EHN PF06441.12 OAG23501.1 - 9.6e-35 119.2 0.3 1.5e-34 118.6 0.3 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG23501.1 - 5.8e-08 32.7 0.1 2.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG23501.1 - 0.0017 19.0 0.7 0.0049 17.5 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_7 PF13508.7 OAG23502.1 - 3.3e-07 30.6 0.0 4.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG23502.1 - 6.5e-07 29.6 0.0 5.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG23502.1 - 3e-06 27.2 0.0 9.8e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF977 PF06163.11 OAG23502.1 - 0.046 13.7 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Acetyltransf_CG PF14542.6 OAG23502.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase VIT1 PF01988.19 OAG23503.1 - 4.8e-13 49.5 0.1 6.5e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 VIT family CDH-cyt PF16010.5 OAG23504.1 - 1.7e-12 47.4 0.9 2.5e-12 46.8 0.9 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 OAG23504.1 - 2.3e-08 33.8 4.9 6.4e-08 32.3 0.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 OAG23504.1 - 2.4e-07 31.0 11.8 4.7e-07 30.0 11.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4271 PF14093.6 OAG23504.1 - 0.015 15.2 2.8 0.015 15.2 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF998 PF06197.13 OAG23504.1 - 0.18 11.4 8.0 0.74 9.4 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF2852 PF11014.8 OAG23504.1 - 0.19 11.9 0.3 0.76 9.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF4079 PF13301.6 OAG23504.1 - 0.3 11.2 5.7 0.31 11.2 2.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF4282 PF14110.6 OAG23504.1 - 1.9 9.3 11.1 9.1 7.1 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) DUF202 PF02656.15 OAG23504.1 - 2 8.9 10.8 22 5.6 4.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PMP22_Claudin PF00822.20 OAG23504.1 - 5.6 6.8 6.2 2.4 8.0 2.7 2.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF983 PF06170.12 OAG23504.1 - 7.2 7.1 6.2 4.2 7.8 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF983) DUF2157 PF09925.9 OAG23504.1 - 7.6 6.3 8.9 14 5.5 4.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) adh_short_C2 PF13561.6 OAG23508.1 - 5.8e-58 196.2 0.2 6.7e-58 196.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG23508.1 - 6.5e-50 169.3 0.0 7.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG23508.1 - 1.8e-14 54.1 0.0 2.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG23508.1 - 0.0004 19.9 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG23508.1 - 0.0027 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAG23508.1 - 0.016 15.1 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_trans_4_2 PF13477.6 OAG23508.1 - 0.041 13.9 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.6 OAG23508.1 - 0.054 13.9 0.0 8.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DFP PF04127.15 OAG23508.1 - 0.063 13.1 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_transf_4 PF13439.6 OAG23508.1 - 0.13 12.3 0.0 18 5.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Dak1 PF02733.17 OAG23509.1 - 1.5e-99 332.9 0.0 2.3e-99 332.2 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAG23509.1 - 1.2e-36 126.3 0.2 2e-36 125.5 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain PIG-F PF06699.11 OAG23510.1 - 6.4e-68 228.5 5.2 7.5e-68 228.2 5.2 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4396 PF14342.6 OAG23510.1 - 0.089 13.2 0.9 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Gly-zipper_YMGG PF13441.6 OAG23510.1 - 0.12 12.1 7.1 1.7 8.5 6.9 2.2 1 1 1 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 OAG23510.1 - 0.35 11.0 3.3 19 5.5 0.4 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 OAG23510.1 - 0.86 9.4 5.4 6.8 6.6 0.4 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_Omp PF13488.6 OAG23510.1 - 2.4 8.2 8.1 23 5.1 8.1 2.2 1 1 0 1 1 1 0 Glycine zipper Translin PF01997.16 OAG23511.1 - 8.4e-47 159.8 0.0 9.8e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Translin family Zn_clus PF00172.18 OAG23513.1 - 1.2e-07 31.7 8.5 2.6e-07 30.6 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG23513.1 - 8.6e-07 28.1 0.1 1.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chs7 PF12271.8 OAG23516.1 - 6.2e-124 413.0 18.5 7.1e-124 412.8 18.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF5080 PF16883.5 OAG23516.1 - 0.0047 17.1 0.4 0.0047 17.1 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5080) DUF4281 PF14108.6 OAG23516.1 - 0.0062 16.9 5.4 0.0062 16.9 5.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4281) DUF3382 PF11862.8 OAG23516.1 - 0.022 15.0 0.8 0.022 15.0 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) FAD_binding_3 PF01494.19 OAG23517.1 - 2.2e-68 231.1 0.0 5.9e-68 229.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG23517.1 - 1.5e-45 155.3 0.1 3.4e-45 154.0 0.1 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 OAG23517.1 - 0.041 12.9 0.0 2 7.4 0.0 2.5 3 0 0 3 3 3 0 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG23517.1 - 0.043 13.1 0.3 0.25 10.5 0.3 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AtuA PF07287.11 OAG23521.1 - 2.4e-125 417.9 0.2 2.8e-125 417.7 0.2 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA F-box PF00646.33 OAG23522.1 - 4.4e-08 32.8 0.2 9.7e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG23522.1 - 1e-07 31.7 0.6 2.1e-07 30.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like MGC-24 PF05283.11 OAG23523.1 - 4.6 7.7 9.9 0.25 11.8 3.0 2.0 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ADH_N PF08240.12 OAG23524.1 - 2.4e-27 95.0 1.7 4.6e-27 94.1 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG23524.1 - 1.2e-23 83.5 0.1 2.1e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG23524.1 - 6.3e-07 30.5 0.0 1.6e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG23524.1 - 3.9e-05 23.2 0.1 6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus HET PF06985.11 OAG23526.1 - 1.2e-22 80.8 0.0 4.6e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Response_reg PF00072.24 OAG23527.1 - 1.2e-22 80.2 0.2 3.3e-22 78.8 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG23527.1 - 5.5e-21 75.2 0.0 1.2e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG23527.1 - 1.6e-09 37.6 0.1 2.8e-08 33.7 0.0 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 OAG23527.1 - 3.5e-08 33.3 0.1 0.0012 18.9 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OAG23527.1 - 3.7e-06 26.9 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAG23527.1 - 1.4e-05 25.3 0.0 0.078 13.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 OAG23527.1 - 1.7e-05 25.0 0.0 0.00051 20.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG23527.1 - 1.9e-05 24.8 0.0 0.0059 16.8 0.0 3.1 3 0 0 3 3 3 1 PAS domain DUF2795 PF11387.8 OAG23528.1 - 0.073 13.3 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Chitin_bind_1 PF00187.19 OAG23529.1 - 0.032 14.7 21.4 0.032 14.7 21.4 3.3 3 1 0 3 3 3 0 Chitin recognition protein adh_short_C2 PF13561.6 OAG23530.1 - 1.1e-29 103.6 2.6 2.7e-19 69.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG23530.1 - 1.7e-15 57.0 1.3 5e-11 42.4 1.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase 3HCDH_N PF02737.18 OAG23530.1 - 0.0023 17.8 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG23530.1 - 0.0032 17.7 0.1 0.005 17.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OAG23530.1 - 0.006 16.2 0.2 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 OAG23530.1 - 0.0076 16.9 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 OAG23530.1 - 0.02 15.1 0.0 0.052 13.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.19 OAG23530.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.24 OAG23530.1 - 0.11 12.1 1.5 0.19 11.3 0.8 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG23530.1 - 0.18 10.8 0.3 0.28 10.2 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TRAPP PF04051.16 OAG23531.1 - 1.1e-39 135.4 0.0 1.3e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Thioredoxin PF00085.20 OAG23532.1 - 1.7e-25 89.0 0.0 3.1e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG23532.1 - 6.6e-08 33.0 0.8 2.9e-07 30.9 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG23532.1 - 7.6e-08 32.6 0.0 2e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAG23532.1 - 4.2e-06 26.3 0.0 5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAG23532.1 - 1.9e-05 24.6 0.2 0.026 14.4 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 OAG23532.1 - 0.00057 19.6 0.3 0.016 15.0 0.1 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 OAG23532.1 - 0.0058 16.8 0.1 0.012 15.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like PHB_depo_C PF06850.11 OAG23532.1 - 0.018 14.5 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus HyaE PF07449.11 OAG23532.1 - 0.034 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 OAG23532.1 - 0.045 13.4 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 OAG23532.1 - 0.066 13.0 0.0 0.066 13.0 0.0 1.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 OAG23532.1 - 0.066 13.4 0.1 2.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin Thioredoxin PF00085.20 OAG23533.1 - 4.5e-59 196.8 0.0 7.3e-30 103.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OAG23533.1 - 1e-22 80.8 1.3 2.7e-22 79.5 0.3 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 OAG23533.1 - 2e-16 60.4 0.0 2e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG23533.1 - 3.3e-15 56.2 0.0 5.1e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OAG23533.1 - 9.8e-09 35.3 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 OAG23533.1 - 1.4e-07 31.5 0.0 0.0036 17.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 OAG23533.1 - 1.9e-07 31.3 0.0 0.02 15.2 0.0 3.9 3 2 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.13 OAG23533.1 - 8.1e-06 26.0 0.0 0.032 14.4 0.0 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain HyaE PF07449.11 OAG23533.1 - 1.7e-05 24.7 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 OAG23533.1 - 2.3e-05 24.4 0.0 0.0093 15.9 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 OAG23533.1 - 5.1e-05 23.2 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OAG23533.1 - 7.8e-05 22.4 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 OAG23533.1 - 0.00035 20.3 0.4 0.29 10.9 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.6 OAG23533.1 - 0.0017 18.6 0.8 2.1 8.5 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin Glutaredoxin PF00462.24 OAG23533.1 - 0.0091 16.2 1.7 2.8 8.2 0.1 3.2 2 2 0 2 2 2 1 Glutaredoxin HSBP1 PF06825.12 OAG23534.1 - 1.5e-20 72.8 0.2 1.7e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 OAG23534.1 - 0.0039 17.5 0.4 0.0046 17.3 0.4 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 OAG23534.1 - 0.019 14.8 0.8 0.068 13.0 0.8 1.8 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.18 OAG23534.1 - 0.021 14.7 0.5 0.026 14.4 0.5 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SRA1 PF07304.11 OAG23534.1 - 0.033 14.0 0.1 0.036 13.9 0.1 1.0 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Trimer_CC PF08954.11 OAG23534.1 - 0.044 13.3 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Trimerisation motif NPV_P10 PF05531.12 OAG23534.1 - 0.077 13.5 0.7 0.11 13.0 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Corona_S2 PF01601.16 OAG23534.1 - 0.11 11.0 0.8 0.12 10.8 0.8 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ebp2 PF05890.12 OAG23535.1 - 1.6e-95 319.7 18.7 1.6e-95 319.7 18.7 2.3 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SR-25 PF10500.9 OAG23536.1 - 2.3 7.8 11.5 3.3 7.2 11.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5470 PF17564.2 OAG23536.1 - 2.8 8.2 7.0 5.1 7.4 7.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) CBFB_NFYA PF02045.15 OAG23537.1 - 8.4e-10 39.1 3.1 1.8e-09 38.1 3.1 1.5 1 1 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Glyco_hydro_61 PF03443.14 OAG23538.1 - 1.4e-46 159.1 0.1 2.8e-46 158.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 HET PF06985.11 OAG23540.1 - 1.9e-25 89.9 0.0 7.4e-24 84.8 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 OAG23541.1 - 4.8e-118 394.9 20.9 5.8e-118 394.6 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG23541.1 - 5.5e-24 84.7 33.9 6.2e-21 74.7 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG23541.1 - 0.0027 16.2 1.1 0.0027 16.2 1.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YajC PF02699.15 OAG23542.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit adh_short PF00106.25 OAG23543.1 - 1.2e-22 80.4 0.0 3.6e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23543.1 - 9.4e-12 45.0 0.0 1.2e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23543.1 - 5.2e-05 23.2 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG23543.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 OAG23544.1 - 1.5e-48 165.7 0.0 2.1e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG23544.1 - 4.9e-30 105.0 0.0 1.4e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG23544.1 - 0.0014 18.8 0.0 0.004 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG23544.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG23544.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.23 OAG23545.1 - 7.7e-20 71.1 0.4 1.4e-19 70.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG23545.1 - 0.052 13.7 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Berberine and berberine like Chitin_synth_1 PF01644.17 OAG23547.1 - 1.6e-66 223.3 0.0 2.4e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OAG23547.1 - 1.7e-26 92.9 0.0 6.9e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 OAG23547.1 - 9e-26 89.6 0.1 1.6e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 OAG23547.1 - 6.7e-10 39.2 1.6 1.1e-09 38.5 0.1 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 DUF2070 PF09843.9 OAG23547.1 - 3.2 5.9 7.6 5.7 5.1 7.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3292 PF11696.8 OAG23548.1 - 0 1027.1 0.0 0 1026.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) SAP PF02037.27 OAG23549.1 - 3.8e-07 29.7 0.7 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 2 SAP domain CPSase_L_D3 PF02787.19 OAG23549.1 - 0.055 13.8 0.1 0.055 13.8 0.1 2.7 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF4569 PF15133.6 OAG23549.1 - 6.4 6.4 9.0 11 5.6 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) GldM_N PF12081.8 OAG23550.1 - 0.013 15.6 3.6 0.023 14.8 3.6 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Baculo_PEP_C PF04513.12 OAG23550.1 - 0.02 14.9 0.5 0.076 13.1 0.2 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Caudo_TAP PF02413.17 OAG23550.1 - 0.11 12.6 0.8 0.24 11.6 0.8 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK BT1 PF03092.16 OAG23550.1 - 0.16 10.1 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 BT1 family Het-C PF07217.11 OAG23550.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Methyltransf_23 PF13489.6 OAG23551.1 - 2.5e-18 66.5 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG23551.1 - 3.4e-10 39.9 0.0 2.1e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG23551.1 - 6e-09 36.5 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG23551.1 - 4.5e-07 30.4 0.0 9.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG23551.1 - 2.8e-06 28.0 0.0 1.2e-05 25.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG23551.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG23551.1 - 9.8e-05 22.5 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 OAG23551.1 - 0.00078 18.8 0.0 0.002 17.5 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OAG23551.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 OAG23551.1 - 0.028 13.4 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.13 OAG23551.1 - 0.061 13.7 0.0 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 OAG23551.1 - 0.063 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAG23551.1 - 0.078 12.3 0.0 0.86 8.9 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAG23551.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 OAG23551.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 OAG23552.1 - 6.3e-46 157.1 0.0 8.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAR1 PF03101.15 OAG23553.1 - 1.6e-08 35.1 1.3 4.5e-08 33.7 1.3 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain FAM76 PF16046.5 OAG23553.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 FAM76 protein NYD-SP28_assoc PF14775.6 OAG23553.1 - 0.12 12.5 1.1 0.29 11.3 1.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain SHE3 PF17078.5 OAG23553.1 - 0.25 11.0 3.1 0.44 10.2 3.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Ndc80_HEC PF03801.13 OAG23554.1 - 9.1e-57 191.0 1.3 1.9e-56 189.9 1.3 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family NPV_P10 PF05531.12 OAG23554.1 - 0.62 10.6 12.5 1.6 9.3 0.6 4.7 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1759 PF03564.15 OAG23554.1 - 1.1 9.2 7.4 0.22 11.5 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4094 PF13334.6 OAG23554.1 - 1.2 9.6 10.4 5.9 7.4 1.4 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) ISN1 PF06437.11 OAG23556.1 - 2.1e-184 613.2 0.0 2.3e-184 613.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Med17 PF10156.9 OAG23557.1 - 3.7e-96 322.6 0.0 4.9e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Nup54 PF13874.6 OAG23557.1 - 0.014 15.5 1.1 0.031 14.4 1.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MRJP PF03022.16 OAG23558.1 - 6.6e-31 107.7 0.0 1.4e-30 106.7 0.0 1.5 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OAG23558.1 - 0.0028 17.3 0.0 0.12 11.9 0.0 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAG23558.1 - 0.019 15.0 0.2 14 5.9 0.0 4.2 5 0 0 5 5 5 0 NHL repeat Str_synth PF03088.16 OAG23558.1 - 0.16 12.1 0.1 87 3.3 0.0 3.3 3 0 0 3 3 3 0 Strictosidine synthase ADH_zinc_N PF00107.26 OAG23559.1 - 6.1e-14 52.1 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG23559.1 - 0.033 14.1 0.0 0.15 12.0 0.0 2.1 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-like domain RRM_1 PF00076.22 OAG23560.1 - 7.6e-09 35.3 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG23560.1 - 7.1e-06 25.8 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG23560.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif USP8_dimer PF08969.11 OAG23560.1 - 0.22 11.7 2.1 0.5 10.6 2.1 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Pkinase PF00069.25 OAG23561.1 - 2.1e-69 233.8 0.0 2.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23561.1 - 2.8e-31 108.7 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG23561.1 - 0.019 14.3 0.0 0.13 11.6 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAG23561.1 - 0.044 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG23561.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SNAD4 PF18750.1 OAG23563.1 - 0.97 9.6 2.6 0.74 10.0 1.0 1.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Polysacc_deac_1 PF01522.21 OAG23564.1 - 7.5e-28 96.9 0.1 2.3e-27 95.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG23564.1 - 6.2e-25 87.4 109.8 3e-06 27.6 20.1 4.8 4 0 0 4 4 4 4 Chitin recognition protein DUF2334 PF10096.9 OAG23564.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Kelch_4 PF13418.6 OAG23567.1 - 1.2e-24 86.0 15.1 7.7e-08 32.2 0.8 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG23567.1 - 4.9e-23 80.9 13.2 2.1e-07 31.1 0.4 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG23567.1 - 5.8e-23 80.2 7.7 3.2e-10 39.4 0.7 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OAG23567.1 - 2.8e-22 78.2 4.9 1.5e-08 34.6 0.1 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OAG23567.1 - 6.4e-20 70.7 9.8 0.0011 18.9 0.0 7.0 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OAG23567.1 - 1.8e-11 43.6 12.8 0.00091 19.1 0.9 6.5 7 1 0 7 7 7 3 Kelch motif ABC1 PF03109.16 OAG23568.1 - 2.2e-21 76.2 0.0 5e-12 46.0 0.0 2.4 1 1 1 2 2 2 2 ABC1 family RIO1 PF01163.22 OAG23568.1 - 0.044 13.4 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Raf1_HTH PF18579.1 OAG23568.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain POTRA_TamA_1 PF17243.2 OAG23568.1 - 0.051 13.7 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Pyr_redox_2 PF07992.14 OAG23569.1 - 4.4e-18 65.5 0.0 8.7e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG23569.1 - 2e-16 59.6 0.2 5.6e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG23569.1 - 1.1e-12 47.8 0.0 1.4e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG23569.1 - 6e-10 38.8 0.0 7e-09 35.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG23569.1 - 5.8e-08 32.9 0.0 1e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG23569.1 - 8.2e-05 21.8 0.0 0.0095 15.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG23569.1 - 0.00012 22.5 0.1 0.029 14.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG23569.1 - 0.0003 20.8 0.6 6.8 6.7 0.1 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG23569.1 - 0.0012 18.2 0.3 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAG23569.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAG23569.1 - 0.009 15.3 0.1 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG23569.1 - 0.04 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG23569.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 OAG23569.1 - 0.24 10.1 1.2 3.1 6.4 0.2 2.6 3 0 0 3 3 3 0 HI0933-like protein Cellulase PF00150.18 OAG23571.1 - 7.9e-13 48.5 1.9 2.7e-12 46.7 1.9 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ENOD93 PF03386.14 OAG23571.1 - 0.044 13.7 1.5 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein His_Phos_2 PF00328.22 OAG23572.1 - 2e-107 359.9 0.2 2.7e-107 359.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAG23572.1 - 2.9e-34 117.1 0.0 5.9e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAG23572.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 OAG23573.1 - 1.8e-76 256.7 0.0 2.5e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAG23573.1 - 1.4e-17 63.7 0.0 0.0018 18.5 0.0 7.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG23573.1 - 2.7e-17 62.8 31.0 0.00036 21.3 0.4 10.5 11 0 0 11 11 11 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAG23573.1 - 6.4e-05 21.7 0.0 0.00011 20.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 OAG23573.1 - 0.0021 16.8 0.4 4.3 5.9 0.1 3.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG23573.1 - 0.013 14.2 0.0 0.77 8.4 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like PALB2_WD40 PF16756.5 OAG23573.1 - 0.015 14.3 0.0 13 4.5 0.0 3.3 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Lgl_C PF08596.10 OAG23573.1 - 0.066 11.9 0.0 4.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal bZIP_1 PF00170.21 OAG23575.1 - 7.2e-07 29.2 15.0 1.1e-06 28.6 15.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG23575.1 - 7e-05 23.3 10.6 0.00011 22.6 10.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG23575.1 - 8e-05 22.6 19.8 0.00014 21.8 19.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Taxilin PF09728.9 OAG23575.1 - 0.0019 17.5 6.9 0.0027 17.0 6.9 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Spc7 PF08317.11 OAG23575.1 - 0.1 11.5 7.8 0.075 11.9 5.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Phosducin PF02114.16 OAG23575.1 - 0.22 10.4 2.7 0.33 9.9 2.7 1.1 1 0 0 1 1 1 0 Phosducin FapA PF03961.13 OAG23575.1 - 0.28 9.7 2.3 0.38 9.3 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ORC6 PF05460.13 OAG23575.1 - 0.32 10.2 14.2 0.47 9.7 14.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_G5 PF04599.12 OAG23575.1 - 4 6.3 6.7 5.4 5.9 6.7 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein CENP-H PF05837.12 OAG23575.1 - 8.9 6.8 10.1 13 6.2 10.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CRC_subunit PF08624.10 OAG23576.1 - 1.3e-52 177.8 0.1 1.9e-52 177.3 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5050 PF16472.5 OAG23576.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) DAO PF01266.24 OAG23578.1 - 1.3e-50 172.9 0.1 1.5e-50 172.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG23578.1 - 0.001 19.6 0.0 2 9.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG23578.1 - 0.0024 17.2 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG23578.1 - 0.0036 17.5 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAG23578.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA MCRA PF06100.11 OAG23578.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 OAG23578.1 - 0.03 14.3 0.0 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG23578.1 - 0.12 11.0 0.0 0.27 9.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Peptidase_M28 PF04389.17 OAG23580.1 - 3.6e-38 131.2 1.0 5.5e-38 130.7 0.5 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 OAG23580.1 - 2.3e-12 46.8 0.0 5.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG23580.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFIIB PF00382.19 OAG23582.1 - 1.1e-30 105.5 2.8 2e-18 66.2 0.1 3.0 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAG23582.1 - 1.2e-24 86.6 2.0 1.2e-24 86.6 2.0 3.8 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OAG23582.1 - 0.023 14.2 3.6 0.054 13.0 3.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AT_hook PF02178.19 OAG23582.1 - 4.4 7.5 9.4 12 6.1 9.4 1.8 1 0 0 1 1 1 0 AT hook motif Nucleo_P87 PF07267.11 OAG23582.1 - 5.9 5.6 18.3 0.025 13.5 5.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PrmA PF06325.13 OAG23583.1 - 8.9e-11 41.7 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG23583.1 - 9.4e-10 39.1 0.1 2.8e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG23583.1 - 1.5e-08 34.5 0.1 2.4e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG23583.1 - 2e-06 27.0 0.2 3.1e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 OAG23583.1 - 2.7e-06 27.9 0.0 6.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG23583.1 - 3e-05 24.0 0.3 0.0001 22.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG23583.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG23583.1 - 0.00026 20.4 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAG23583.1 - 0.0051 17.5 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG23583.1 - 0.0065 16.0 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG23583.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lum_binding PF00677.17 OAG23585.1 - 1.3e-44 150.1 1.8 2.5e-21 75.4 0.5 2.3 2 0 0 2 2 2 2 Lumazine binding domain YabP PF07873.11 OAG23585.1 - 0.038 13.8 0.1 10 6.0 0.0 3.2 3 0 0 3 3 3 0 YabP family CoA_transf_3 PF02515.17 OAG23586.1 - 1.4e-120 402.8 0.0 2.6e-120 401.9 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III Kinesin PF00225.23 OAG23586.1 - 6.1e-62 209.5 0.0 9.8e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG23586.1 - 1.2e-10 41.5 0.0 1.4e-07 31.6 0.0 2.9 2 1 0 2 2 2 2 Microtubule binding bZIP_2 PF07716.15 OAG23586.1 - 0.029 14.4 2.2 0.094 12.8 2.2 1.9 1 0 0 1 1 1 0 Basic region leucine zipper TSC22 PF01166.18 OAG23586.1 - 0.44 10.9 2.2 0.9 9.9 0.5 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family PHD PF00628.29 OAG23587.1 - 7.3e-11 41.8 7.5 1.2e-10 41.1 7.5 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 OAG23587.1 - 0.00012 21.9 4.2 0.00023 21.0 4.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 OAG23587.1 - 0.00043 19.9 2.6 0.00077 19.1 2.6 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OAG23587.1 - 0.0012 18.6 2.3 0.0023 17.8 2.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 OAG23587.1 - 0.0026 17.9 2.1 0.0039 17.3 2.1 1.2 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type PSCyt3 PF07627.11 OAG23587.1 - 0.032 14.5 0.1 0.69 10.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) PHD_2 PF13831.6 OAG23587.1 - 0.034 13.7 6.0 0.11 12.1 6.0 1.9 1 1 0 1 1 1 0 PHD-finger DTHCT PF08070.11 OAG23587.1 - 0.052 14.3 0.3 0.18 12.5 0.3 2.0 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF5552 PF17706.1 OAG23587.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5552) FYVE_2 PF02318.16 OAG23587.1 - 0.24 11.6 3.7 0.38 11.0 3.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger PBP1_TM PF14812.6 OAG23587.1 - 1.1 9.7 4.3 1 9.8 1.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DZR PF12773.7 OAG23587.1 - 2.8 8.0 6.1 5.4 7.1 6.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon COesterase PF00135.28 OAG23588.1 - 1.8e-93 314.1 0.0 2.4e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG23588.1 - 5.6e-06 26.4 0.2 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG23588.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aa_trans PF01490.18 OAG23589.1 - 1.7e-34 119.2 38.0 1.9e-34 119.0 38.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAG23589.1 - 2.5e-06 26.8 17.2 2.5e-06 26.8 17.2 2.0 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family MFS_1 PF07690.16 OAG23590.1 - 3.9e-33 114.8 23.4 2.1e-28 99.3 4.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG23590.1 - 6e-07 28.7 2.9 6e-07 28.7 2.9 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG23590.1 - 0.015 13.7 0.4 0.022 13.2 0.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CFEM PF05730.11 OAG23591.1 - 2.2e-08 34.1 5.4 9.3e-08 32.1 5.4 2.1 1 0 0 1 1 1 1 CFEM domain OATP PF03137.20 OAG23592.1 - 0.049 11.9 0.1 0.069 11.4 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CRAL_TRIO PF00650.20 OAG23593.1 - 1.3e-09 37.9 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG23593.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RRM_1 PF00076.22 OAG23595.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 OAG23595.1 - 0.0081 16.4 0.3 0.017 15.4 0.3 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding FGGY_C PF02782.16 OAG23596.1 - 2.6e-51 174.2 0.3 4.3e-51 173.5 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG23596.1 - 2.9e-25 89.2 0.9 1.8e-23 83.4 0.9 2.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAG23596.1 - 0.00096 18.7 0.2 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family zf-C2H2_9 PF16293.5 OAG23596.1 - 0.023 14.5 0.1 0.078 12.8 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) DEDD_Tnp_IS110 PF01548.17 OAG23596.1 - 0.2 11.5 0.5 0.89 9.4 0.1 2.2 2 0 0 2 2 2 0 Transposase dCMP_cyt_deam_1 PF00383.23 OAG23599.1 - 2.5e-24 85.1 0.1 4.5e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG23599.1 - 5.3e-19 68.3 0.0 8.4e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAG23599.1 - 0.0022 18.1 0.3 0.02 14.9 0.1 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC3 PF18771.1 OAG23599.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 CD34_antigen PF06365.12 OAG23599.1 - 0.1 12.2 0.3 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family APOBEC4_like PF18774.1 OAG23599.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Cg6151-P PF10233.9 OAG23600.1 - 3.1e-42 143.5 15.3 3.7e-42 143.2 15.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Pox_P21 PF05313.12 OAG23600.1 - 0.12 12.0 7.3 0.16 11.5 4.3 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein DUF3784 PF12650.7 OAG23600.1 - 0.22 11.7 13.2 0.15 12.3 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2070 PF09843.9 OAG23600.1 - 0.8 7.9 9.8 0.92 7.7 9.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HemY_N PF07219.13 OAG23600.1 - 2.1 8.6 7.8 1.2 9.4 0.0 2.3 1 1 1 2 2 2 0 HemY protein N-terminus DUF2518 PF10726.9 OAG23600.1 - 3.8 7.2 8.0 0.24 11.0 0.8 2.0 2 0 0 2 2 2 0 Protein of function (DUF2518) DUF308 PF03729.13 OAG23600.1 - 7.4 7.0 19.2 1.1 9.6 4.9 2.7 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DUF2721 PF11026.8 OAG23600.1 - 7.9 6.4 17.3 0.54 10.2 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Aim21 PF11489.8 OAG23601.1 - 3.4e-235 783.3 63.2 3.4e-235 783.3 63.2 2.9 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 SURF2 PF05477.11 OAG23603.1 - 0.013 15.2 5.0 0.021 14.5 5.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 OAG23603.1 - 0.36 10.1 12.1 0.4 10.0 12.1 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 OAG23603.1 - 0.72 7.9 21.1 0.97 7.5 21.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 OAG23604.1 - 1.2e-06 29.2 2.0 0.25 12.3 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat RNA_pol_N PF01194.17 OAG23605.1 - 2.5e-30 104.6 0.8 3e-30 104.3 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 OAG23605.1 - 0.081 13.2 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Metallophos PF00149.28 OAG23606.1 - 6e-10 40.0 4.5 1.2e-09 39.0 4.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RCC1 PF00415.18 OAG23607.1 - 4e-55 184.2 6.2 3.2e-10 40.4 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG23607.1 - 8.8e-32 108.3 30.9 5e-07 29.3 3.5 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat sCache_3_2 PF17203.4 OAG23607.1 - 0.016 15.3 0.1 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 Single cache domain 3 MAJIN PF15077.6 OAG23607.1 - 5.2 6.8 7.6 10 5.9 7.6 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein TPR_1 PF00515.28 OAG23610.1 - 4.5e-15 54.7 1.1 1e-06 28.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG23610.1 - 6e-14 51.0 1.8 4.6e-05 23.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23610.1 - 2e-09 37.6 0.0 1.1e-05 25.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23610.1 - 8.3e-08 31.9 0.2 0.0012 18.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.24 OAG23610.1 - 4.6e-07 29.7 0.2 8e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 OAG23610.1 - 2.1e-06 27.3 0.1 0.00013 21.7 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG23610.1 - 7.7e-06 25.5 0.2 0.00013 21.5 0.1 2.9 1 1 1 2 2 2 1 TPR repeat TPR_6 PF13174.6 OAG23610.1 - 9.1e-06 26.0 1.1 1.6 9.5 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG23610.1 - 0.00071 19.7 0.3 0.29 11.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG23610.1 - 0.0096 16.6 0.7 0.54 11.0 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23610.1 - 0.021 15.6 0.2 0.79 10.7 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG23610.1 - 0.18 12.2 0.6 3.2 8.3 0.0 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat HMA PF00403.26 OAG23612.1 - 2.8e-13 50.1 0.0 4.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 OAG23612.1 - 1.5e-09 38.1 0.1 2.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 OAG23613.1 - 1.2e-41 141.9 0.0 1.6e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 OAG23614.1 - 4.6e-77 256.6 0.8 6.7e-41 139.6 0.6 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 OAG23615.1 - 3.5e-131 437.6 2.6 4.8e-131 437.2 0.4 2.4 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 OAG23615.1 - 5.7e-41 139.3 0.0 1.9e-36 124.7 0.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 OAG23615.1 - 5.4e-36 122.5 1.4 1.6e-33 114.6 0.1 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 OAG23615.1 - 5.8e-29 100.1 1.0 4.8e-28 97.2 0.2 3.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAG23615.1 - 6.1e-11 42.3 14.6 1.5e-10 41.1 14.6 1.7 1 0 0 1 1 1 1 Hr1 repeat DtxR PF18357.1 OAG23615.1 - 0.11 12.2 0.1 0.6 9.8 0.1 2.3 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain LON_substr_bdg PF02190.16 OAG23616.1 - 1.1e-29 103.9 0.0 1.5e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAG23616.1 - 4.4e-14 52.0 18.6 4.2e-10 39.3 9.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG23616.1 - 2e-13 50.2 17.8 8.3e-07 29.1 5.6 3.0 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG23616.1 - 3.1e-13 49.5 20.4 3.7e-07 30.1 4.7 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 OAG23616.1 - 3.6e-11 42.8 17.8 3.2e-06 27.0 8.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG23616.1 - 4.5e-10 39.2 17.3 1.5e-06 27.9 7.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG23616.1 - 6.2e-10 38.8 17.7 2.5e-05 24.0 9.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG23616.1 - 3.5e-09 36.8 22.6 3.2e-07 30.6 9.3 2.8 2 1 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 OAG23616.1 - 2.9e-08 33.4 20.7 6.3e-06 25.9 8.1 2.8 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAG23616.1 - 4.1e-06 26.8 18.9 1.5e-05 25.0 6.5 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 U-box PF04564.15 OAG23616.1 - 0.0046 17.1 0.1 0.032 14.4 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.6 OAG23616.1 - 0.014 15.2 6.3 0.014 15.2 6.3 3.6 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Slp PF03843.13 OAG23616.1 - 0.022 14.2 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family zf-rbx1 PF12678.7 OAG23616.1 - 0.43 10.9 15.3 0.078 13.3 6.4 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 OAG23616.1 - 6.3 6.9 17.0 5 7.2 4.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 OAG23617.1 - 2.1e-11 43.6 29.2 0.00023 21.7 1.7 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG23617.1 - 6.7e-08 32.6 30.0 0.016 15.6 5.8 5.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 OAG23617.1 - 2.6e-05 24.4 17.8 0.023 15.0 5.4 3.4 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OAG23617.1 - 5.9e-05 23.3 24.6 0.012 16.0 0.6 5.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG23617.1 - 0.00039 20.6 21.8 0.41 11.0 0.3 4.7 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OAG23617.1 - 0.0025 17.6 7.7 0.019 14.9 0.2 3.9 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-met PF12874.7 OAG23617.1 - 0.0028 18.0 19.3 0.045 14.1 0.0 5.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 OAG23617.1 - 0.0029 18.0 0.4 0.12 12.8 0.1 2.9 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 OAG23617.1 - 0.011 15.7 2.2 0.011 15.7 2.2 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger C1_4 PF07975.12 OAG23617.1 - 0.76 10.1 7.5 1.6 9.0 1.4 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain CxC7 PF18866.1 OAG23617.1 - 0.91 9.7 6.7 26 5.0 0.3 3.3 1 1 2 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases DUF2256 PF10013.9 OAG23617.1 - 1.2 9.3 10.1 9.2 6.5 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Sgf11 PF08209.11 OAG23617.1 - 1.7 8.3 9.5 17 5.1 1.1 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_4 PF13717.6 OAG23617.1 - 1.9 8.4 9.1 6.3 6.8 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 OAG23617.1 - 2.1 9.2 0.0 2.1 9.2 0.0 3.6 4 0 0 4 4 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Alpha_GJ PF03229.13 OAG23618.1 - 0.001 19.6 3.6 0.0021 18.6 3.6 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J HOK_GEF PF01848.16 OAG23618.1 - 0.0058 16.0 1.7 0.011 15.2 1.7 1.4 1 0 0 1 1 1 1 Hok/gef family CAP59_mtransfer PF11735.8 OAG23619.1 - 1.8e-67 227.5 0.0 2.2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4078 PF13300.6 OAG23620.1 - 4.2e-26 91.1 13.8 4.2e-26 91.1 13.8 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.19 OAG23621.1 - 7.2e-52 175.8 0.0 9.3e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAG23621.1 - 7.2e-17 62.1 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NB-ARC PF00931.22 OAG23621.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATG11 PF10377.9 OAG23624.1 - 9.1e-45 151.9 0.0 9.1e-45 151.9 0.0 4.2 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 OAG23624.1 - 2.1e-05 23.9 16.9 0.00061 19.0 0.6 5.4 2 2 2 4 4 4 2 Autophagy protein Apg17 Baculo_F PF12259.8 OAG23624.1 - 0.0031 16.1 0.2 0.0031 16.1 0.2 2.3 3 0 0 3 3 3 1 Baculovirus F protein CENP-H PF05837.12 OAG23625.1 - 1.3e-25 89.9 2.6 1.3e-25 89.9 2.6 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Use1 PF09753.9 OAG23625.1 - 0.37 10.5 9.2 0.045 13.5 2.6 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 HMG_box PF00505.19 OAG23626.1 - 1.5e-24 86.1 3.0 2.3e-24 85.6 3.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG23626.1 - 1.3e-18 67.3 3.5 2.1e-18 66.7 3.5 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 OAG23626.1 - 0.012 16.2 0.1 0.012 16.2 0.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 OAG23626.1 - 0.013 15.5 1.9 0.031 14.2 1.9 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 OAG23626.1 - 0.038 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Peptidase_S24 PF00717.23 OAG23628.1 - 8.9e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like PWWP PF00855.17 OAG23629.1 - 0.011 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 PWWP domain LRR_4 PF12799.7 OAG23630.1 - 0.092 13.2 9.5 1.1 9.8 0.3 5.2 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Rad9 PF04139.13 OAG23631.1 - 5.2e-48 163.7 0.1 6.3e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Rad9 Phos_pyr_kin PF08543.12 OAG23632.1 - 1.6e-85 286.4 1.8 2.7e-85 285.7 1.8 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DEAD PF00270.29 OAG23632.1 - 2.5e-49 167.4 0.0 1.5e-48 164.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TENA_THI-4 PF03070.16 OAG23632.1 - 3.1e-49 167.6 0.1 4.9e-49 167.0 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Helicase_C PF00271.31 OAG23632.1 - 3.9e-30 104.5 0.1 8.5e-30 103.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PfkB PF00294.24 OAG23632.1 - 6.9e-09 35.4 0.1 5.1e-08 32.6 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ResIII PF04851.15 OAG23632.1 - 0.00063 19.8 0.0 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG23632.1 - 0.0024 18.2 0.0 0.33 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 OAG23632.1 - 0.025 13.3 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Reprolysin_2 PF13574.6 OAG23635.1 - 0.11 12.4 0.7 0.17 11.7 0.7 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Bd3614-deam PF14439.6 OAG23636.1 - 0.066 13.3 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase PPR_2 PF13041.6 OAG23637.1 - 3.2e-21 75.3 0.0 1.4e-17 63.6 0.0 3.7 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 OAG23637.1 - 1.2e-05 25.2 0.4 0.0037 17.4 0.0 3.9 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 OAG23637.1 - 2.8e-05 24.1 0.0 1.8 8.7 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAG23637.1 - 0.00065 19.3 1.0 1.6 8.5 0.0 3.1 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 OAG23637.1 - 0.0051 16.2 0.0 0.1 11.9 0.0 2.7 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP Rtf2 PF04641.12 OAG23638.1 - 2.9e-53 180.9 3.4 3.9e-53 180.5 3.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OAG23638.1 - 0.00014 21.6 0.0 0.0027 17.5 0.0 2.5 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RNase_T PF00929.24 OAG23639.1 - 6.3e-24 85.4 0.2 7.2e-24 85.2 0.2 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_B PF00136.21 OAG23640.1 - 1e-114 383.8 0.7 1.6e-114 383.1 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OAG23640.1 - 1.1e-61 207.8 0.0 2.4e-61 206.7 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAG23640.1 - 1.3e-41 142.8 0.0 3.9e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAG23640.1 - 1.4e-24 86.0 6.4 3.9e-24 84.5 6.4 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 OAG23640.1 - 0.021 13.7 0.1 0.11 11.4 0.0 2.1 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral Aminotran_5 PF00266.19 OAG23641.1 - 2.1e-11 43.4 0.0 5.5e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG23641.1 - 0.017 13.7 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fe-S_biosyn PF01521.20 OAG23642.1 - 2.2e-12 47.2 0.0 2.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ADH_N PF08240.12 OAG23643.1 - 1.4e-08 34.5 0.0 4.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG23643.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG23643.1 - 0.0052 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 OAG23644.1 - 6.1e-12 45.1 0.1 1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23644.1 - 0.00055 20.0 1.2 0.0012 18.9 1.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP_assoc PF03828.19 OAG23645.1 - 1.8e-23 82.5 0.0 4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG23645.1 - 0.0035 17.6 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG23645.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 OAG23645.1 - 0.065 12.2 0.2 0.48 9.4 0.1 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain SGP PF17228.2 OAG23645.1 - 0.46 11.4 6.0 0.091 13.6 0.7 2.2 2 0 0 2 2 2 0 Sulphur globule protein MFS_1 PF07690.16 OAG23647.1 - 3.8e-24 85.3 37.0 3.8e-24 85.3 37.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF383 PF04063.14 OAG23648.1 - 1.6e-68 230.1 0.1 1.8e-67 226.7 0.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAG23648.1 - 7.9e-21 73.7 3.2 1.7e-20 72.6 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF2019 PF09450.10 OAG23648.1 - 0.097 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Abhydrolase_6 PF12697.7 OAG23650.1 - 7.6e-10 39.8 0.0 9.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG23650.1 - 2.1e-08 34.1 0.2 1.4e-07 31.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG23650.1 - 0.0001 21.7 0.0 0.00091 18.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG23650.1 - 0.0087 15.9 0.0 2.2 8.0 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase ARID PF01388.21 OAG23651.1 - 0.12 13.1 0.0 0.37 11.5 0.0 1.9 1 1 1 2 2 2 0 ARID/BRIGHT DNA binding domain Peptidase_S41 PF03572.18 OAG23653.1 - 1e-06 28.4 0.0 2.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 HET PF06985.11 OAG23654.1 - 1.3e-20 74.2 0.0 4e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG23654.1 - 0.00021 21.2 0.4 0.0023 17.9 0.4 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG23654.1 - 0.00061 20.2 0.5 0.003 18.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG23654.1 - 0.004 17.4 0.1 0.072 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG23654.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG23654.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG23654.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 OAG23654.1 - 0.076 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 OAG23654.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG23654.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 OAG23654.1 - 0.11 12.6 0.1 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OAG23654.1 - 0.13 12.6 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG23654.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG23654.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 OAG23654.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MobB PF03205.14 OAG23654.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhaP_Bmeg PF09602.10 OAG23655.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2457 PF10446.9 OAG23656.1 - 0.023 13.9 5.4 0.031 13.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pepsin-I3 PF06394.13 OAG23657.1 - 0.044 14.0 1.9 0.33 11.2 0.0 3.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF722 PF05263.11 OAG23657.1 - 5.4 7.3 8.6 0.46 10.7 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF722) gpW PF02831.15 OAG23657.1 - 6.4 6.8 6.2 1.7 8.6 0.0 3.2 4 0 0 4 4 4 0 gpW FHA PF00498.26 OAG23658.1 - 9.2e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Glyco_hydro_47 PF01532.20 OAG23659.1 - 6.2e-179 595.7 0.0 7.3e-179 595.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF5011 PF16403.5 OAG23661.1 - 0.19 11.9 1.0 0.94 9.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) I-set PF07679.16 OAG23661.1 - 0.36 10.9 2.0 22 5.2 0.0 4.3 5 0 0 5 5 5 0 Immunoglobulin I-set domain Peptidase_C12 PF01088.21 OAG23662.1 - 3.3e-53 180.6 0.1 5.4e-53 179.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MecA PF05389.12 OAG23662.1 - 0.33 10.5 2.9 0.42 10.2 0.3 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) YccV-like PF08755.11 OAG23663.1 - 6e-28 97.2 0.1 1.8e-27 95.7 0.1 1.9 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 OAG23663.1 - 5.4e-17 61.8 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 OAG23663.1 - 3.6e-09 36.4 0.0 7.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 OAG23663.1 - 8.7e-05 23.0 0.1 0.00018 22.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 OAG23663.1 - 0.00098 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG23663.1 - 0.0027 17.6 0.3 0.0069 16.3 0.3 1.7 1 1 0 1 1 1 1 F-box Vinculin PF01044.19 OAG23663.1 - 0.092 11.0 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Vinculin family CRAL_TRIO PF00650.20 OAG23665.1 - 3.9e-24 85.2 0.0 5.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG23665.1 - 7.2e-09 35.7 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF4748 PF15932.5 OAG23667.1 - 0.096 12.5 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Sugar_tr PF00083.24 OAG23668.1 - 8.6e-124 413.8 23.9 9.9e-124 413.6 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG23668.1 - 2.2e-20 72.9 36.0 5e-14 52.0 20.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 OAG23668.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BTB PF00651.31 OAG23669.1 - 1.2e-10 41.6 0.1 2.8e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Linker_histone PF00538.19 OAG23670.1 - 1e-26 93.1 0.1 1e-26 93.1 0.1 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family Ribonuclease_T2 PF00445.18 OAG23673.1 - 3e-42 144.9 0.6 3e-42 144.9 0.6 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family SHMT PF00464.19 OAG23674.1 - 8.9e-203 673.2 0.0 1e-202 673.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OAG23674.1 - 0.00011 21.6 0.0 0.00029 20.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAG23674.1 - 0.00013 21.3 0.0 0.00033 19.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Fig1 PF12351.8 OAG23675.1 - 1.8e-59 200.9 3.6 1.8e-59 200.9 3.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 OAG23675.1 - 1.3e-09 38.1 7.5 2.1e-09 37.3 7.5 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 OAG23675.1 - 0.13 11.3 12.3 0.39 9.7 12.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF751 PF05421.11 OAG23675.1 - 0.54 11.0 0.1 0.54 11.0 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF751) HSP9_HSP12 PF04119.12 OAG23676.1 - 3.5e-21 75.4 8.4 5.8e-21 74.6 8.4 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 DEAD PF00270.29 OAG23677.1 - 4.5e-22 78.7 0.0 4e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG23677.1 - 9.3e-21 74.3 0.0 4e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG23677.1 - 2.9e-15 56.7 3.9 1.2e-14 54.7 3.9 2.2 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 OAG23677.1 - 2.6e-14 53.0 0.1 6.3e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 OAG23677.1 - 7.5e-08 32.3 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 OAG23677.1 - 1.2e-06 28.6 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pyridoxal_deC PF00282.19 OAG23678.1 - 4.7e-27 94.7 0.0 1.1e-26 93.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAG23678.1 - 0.002 17.4 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SMC_N PF02463.19 OAG23680.1 - 7e-69 231.6 30.5 2.2e-68 230.0 30.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG23680.1 - 3.4e-25 88.6 0.3 2e-24 86.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG23680.1 - 6.4e-12 45.9 1.3 4.3e-05 23.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ERM PF00769.19 OAG23680.1 - 3.4e-05 23.8 12.5 3.4e-05 23.8 12.5 6.1 2 2 4 6 6 4 1 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.19 OAG23680.1 - 0.00012 20.1 47.5 0.00012 20.1 47.5 3.3 2 1 0 3 3 3 1 Myosin tail MAD PF05557.13 OAG23680.1 - 0.00026 19.5 17.7 0.00026 19.5 17.7 5.0 2 2 3 5 5 5 2 Mitotic checkpoint protein HOOK PF05622.12 OAG23680.1 - 0.00055 18.2 11.5 0.00055 18.2 11.5 5.3 2 2 2 4 4 2 1 HOOK protein Tektin PF03148.14 OAG23680.1 - 0.0006 18.7 9.9 0.0006 18.7 9.9 6.1 3 2 2 5 5 4 2 Tektin family AAA_29 PF13555.6 OAG23680.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UPF0242 PF06785.11 OAG23680.1 - 0.0015 18.7 6.8 0.0015 18.7 6.8 7.2 3 2 4 7 7 3 2 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 OAG23680.1 - 0.0019 17.9 1.0 0.0019 17.9 1.0 11.2 7 4 5 12 12 12 1 Septum formation initiator GAS PF13851.6 OAG23680.1 - 0.004 16.5 6.8 0.004 16.5 6.8 8.0 4 3 3 7 7 6 4 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 OAG23680.1 - 0.0064 16.4 10.5 0.0064 16.4 10.5 9.8 7 4 2 10 10 9 1 Prefoldin subunit APG6_N PF17675.1 OAG23680.1 - 0.0072 16.8 9.7 0.0072 16.8 9.7 9.3 2 2 6 9 9 8 3 Apg6 coiled-coil region HemX PF04375.14 OAG23680.1 - 0.024 13.9 0.3 0.024 13.9 0.3 8.2 3 2 5 8 8 8 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_13 PF13166.6 OAG23680.1 - 3.8 6.0 96.8 0.0039 15.9 8.0 5.8 2 2 2 5 5 5 0 AAA domain AT_hook PF02178.19 OAG23680.1 - 6.5 7.0 12.8 0.25 11.3 3.6 2.9 2 0 0 2 2 2 0 AT hook motif DUF3591 PF12157.8 OAG23682.1 - 3.6e-170 566.4 0.4 5.8e-170 565.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 OAG23682.1 - 0.0051 16.8 0.7 0.009 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OAG23682.1 - 0.0099 15.7 1.1 0.027 14.3 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle ANTAR PF03861.14 OAG23682.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain SCIMP PF15050.6 OAG23682.1 - 5.8 7.4 6.4 50 4.4 0.1 3.4 3 0 0 3 3 3 0 SCIMP protein ARID PF01388.21 OAG23683.1 - 7e-17 61.9 0.3 2.1e-16 60.4 0.3 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 OAG23683.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Collagen PF01391.18 OAG23683.1 - 0.43 10.4 7.2 1 9.1 7.2 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) AAA PF00004.29 OAG23684.1 - 2.9e-45 153.9 0.7 6.6e-45 152.8 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG23684.1 - 6.3e-10 38.9 0.1 4e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAG23684.1 - 9.5e-09 35.4 0.1 3.1e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG23684.1 - 6.4e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG23684.1 - 1.1e-07 32.4 0.1 3.5e-05 24.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAG23684.1 - 7.1e-06 25.4 0.2 1.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAG23684.1 - 5e-05 23.6 1.4 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 OAG23684.1 - 0.00023 20.9 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OAG23684.1 - 0.00033 20.5 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG23684.1 - 0.00058 20.4 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OAG23684.1 - 0.00079 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 OAG23684.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 OAG23684.1 - 0.0015 18.5 0.0 0.021 14.9 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG23684.1 - 0.0019 17.7 0.1 0.0096 15.4 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OAG23684.1 - 0.0019 18.2 0.1 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAG23684.1 - 0.0025 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 OAG23684.1 - 0.0036 17.2 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OAG23684.1 - 0.0054 16.5 0.1 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG23684.1 - 0.0063 16.7 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAG23684.1 - 0.0066 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAG23684.1 - 0.0086 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 OAG23684.1 - 0.0088 15.5 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 OAG23684.1 - 0.0088 16.0 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 OAG23684.1 - 0.017 14.8 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAG23684.1 - 0.018 14.8 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG23684.1 - 0.036 14.0 0.8 0.21 11.5 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OAG23684.1 - 0.038 13.3 1.6 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 OAG23684.1 - 0.04 13.5 0.7 0.26 10.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 OAG23684.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_Hsp90 PF03225.14 OAG23684.1 - 0.05 12.1 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Bac_DnaA PF00308.18 OAG23684.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 OAG23684.1 - 0.079 12.7 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 OAG23684.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase AAA_19 PF13245.6 OAG23684.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG23684.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 OAG23684.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIP5K PF01504.18 OAG23685.1 - 1.3e-102 342.7 0.3 1.3e-102 342.7 0.3 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Lactamase_B_3 PF13483.6 OAG23686.1 - 5e-08 33.0 0.0 1.2e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG23686.1 - 3.7e-05 23.3 0.1 6.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain C1_2 PF03107.16 OAG23687.1 - 0.83 10.0 8.1 2.5 8.5 8.1 1.8 1 0 0 1 1 1 0 C1 domain GRASP55_65 PF04495.14 OAG23689.1 - 7.8e-51 172.0 0.0 1.3e-47 161.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAG23689.1 - 0.00061 19.6 0.1 0.1 12.5 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OAG23689.1 - 0.097 13.0 0.0 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Methyltransf_15 PF09445.10 OAG23690.1 - 7.7e-51 171.9 0.0 9.6e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAG23690.1 - 1.5e-08 34.6 0.0 2e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OAG23690.1 - 2.9e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 OAG23690.1 - 4.9e-06 26.4 0.0 5.5e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 OAG23690.1 - 0.00088 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_18 PF12847.7 OAG23690.1 - 0.0064 16.4 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG23690.1 - 0.0071 17.0 0.0 0.012 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG23690.1 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DNA_methylase PF00145.17 OAG23690.1 - 0.047 13.0 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_5 PF01795.19 OAG23690.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family PrmA PF06325.13 OAG23690.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 OAG23690.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Abhydrolase_2 PF02230.16 OAG23691.1 - 5.8e-30 104.7 0.0 8.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAG23691.1 - 0.0025 17.1 0.2 6.3 6.0 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Cutinase PF01083.22 OAG23691.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Cutinase zf-HIT PF04438.16 OAG23692.1 - 1.1e-08 34.7 5.0 1.7e-08 34.2 5.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-ribbon_3 PF13248.6 OAG23692.1 - 0.35 10.4 5.5 10 5.7 0.9 2.5 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OAG23692.1 - 1.5 8.7 5.5 12 5.7 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain NRDD PF13597.6 OAG23692.1 - 6.3 5.5 5.1 13 4.4 5.1 1.5 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase adh_short PF00106.25 OAG23693.1 - 1e-20 74.0 0.1 3e-15 56.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23693.1 - 1.2e-12 47.9 0.1 2e-11 43.9 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23693.1 - 1.4e-06 28.3 0.1 3.3e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF4400 PF14348.6 OAG23694.1 - 0.0092 15.5 0.5 0.0092 15.5 0.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4400) CUE PF02845.16 OAG23695.1 - 4.3e-10 39.1 0.0 6.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 OAG23695.1 - 0.11 12.2 5.6 0.26 11.0 5.6 1.7 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) HTH_32 PF13565.6 OAG23695.1 - 0.18 12.4 0.5 0.18 12.4 0.5 2.2 2 1 0 2 2 2 0 Homeodomain-like domain Metal_resist PF13801.6 OAG23695.1 - 0.62 10.3 10.8 0.56 10.4 1.5 2.6 3 0 0 3 3 3 0 Heavy-metal resistance DPBB_1 PF03330.18 OAG23696.1 - 6.7e-09 35.9 0.1 1.6e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAG23696.1 - 0.0067 16.3 0.7 0.011 15.6 0.2 1.6 2 0 0 2 2 2 1 Barwin family IBR PF01485.21 OAG23699.1 - 9.8e-05 22.5 13.2 0.00037 20.7 6.3 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 OAG23699.1 - 0.059 13.6 0.0 0.059 13.6 0.0 4.0 5 0 0 5 5 5 0 zinc-ribbon CUE PF02845.16 OAG23699.1 - 0.096 12.4 0.1 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 CUE domain MFS_1 PF07690.16 OAG23700.1 - 2.6e-38 131.9 16.3 2.1e-37 128.9 18.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG23700.1 - 7.2e-07 28.8 3.6 7.2e-07 28.8 3.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TssN PF17555.2 OAG23700.1 - 0.28 10.5 2.0 8.9 5.6 0.0 2.7 2 1 0 2 2 2 0 Type VI secretion system, TssN CobD_Cbib PF03186.13 OAG23700.1 - 0.31 10.2 0.0 0.31 10.2 0.0 2.6 3 0 0 3 3 3 0 CobD/Cbib protein GMC_oxred_N PF00732.19 OAG23701.1 - 2.5e-65 220.8 0.0 3.6e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG23701.1 - 6.3e-33 114.3 0.0 1e-32 113.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG23701.1 - 0.00015 20.9 1.0 0.00027 20.1 1.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG23701.1 - 0.0063 15.8 1.4 0.0083 15.4 0.2 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAG23701.1 - 0.019 14.1 2.6 3.1 6.8 1.3 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 OAG23701.1 - 0.89 9.1 3.5 0.52 9.8 1.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Nop14 PF04147.12 OAG23702.1 - 7.9e-05 21.1 15.9 9.9e-05 20.8 15.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAG23702.1 - 0.016 14.7 23.0 0.023 14.2 23.0 1.2 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 OAG23702.1 - 0.12 11.3 2.2 0.16 10.8 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRN3 PF05327.11 OAG23702.1 - 0.17 10.4 9.7 0.23 9.9 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4065 PF13274.6 OAG23702.1 - 0.28 12.1 2.7 0.61 11.0 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) BUD22 PF09073.10 OAG23702.1 - 0.32 10.3 21.5 0.44 9.8 21.5 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 OAG23702.1 - 0.79 8.4 9.5 1.1 7.9 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 OAG23702.1 - 0.97 7.6 17.3 1.4 7.1 17.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAG23702.1 - 1.2 9.1 21.0 2.3 8.3 21.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CPSF100_C PF13299.6 OAG23702.1 - 2.4 8.3 5.3 5.3 7.2 5.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LAP1C PF05609.12 OAG23702.1 - 4.8 6.2 12.3 7.5 5.5 12.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GST_N_4 PF17172.4 OAG23703.1 - 2.3e-16 60.3 0.0 3.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAG23703.1 - 1.1e-06 28.3 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG23703.1 - 0.00046 20.2 0.0 0.00087 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LZ3wCH PF18517.1 OAG23703.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Leucine zipper with capping helix domain GST_N_3 PF13417.6 OAG23703.1 - 0.11 12.9 0.1 2.4 8.6 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p450 PF00067.22 OAG23705.1 - 1.3e-49 169.3 0.0 2.9e-49 168.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PAN_4 PF14295.6 OAG23706.1 - 1.5e-06 28.0 9.4 1.2e-05 25.1 1.8 3.5 4 0 0 4 4 4 2 PAN domain PAN_3 PF08277.12 OAG23706.1 - 0.0065 16.3 2.2 0.0065 16.3 2.2 3.2 4 0 0 4 4 4 2 PAN-like domain LCCL PF03815.19 OAG23707.1 - 5.9e-21 74.4 0.0 1.2e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 LCCL domain DUF1201 PF06716.11 OAG23707.1 - 4 7.5 6.2 0.99 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Erg28 PF03694.13 OAG23708.1 - 1.3e-46 157.5 0.8 1.6e-46 157.2 0.8 1.1 1 0 0 1 1 1 1 Erg28 like protein Ribosomal_S17_N PF16205.5 OAG23709.1 - 2.6e-33 114.2 0.2 4.2e-33 113.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAG23709.1 - 7.8e-25 86.8 0.1 1.3e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 adh_short PF00106.25 OAG23710.1 - 9.5e-39 132.9 0.0 1.3e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23710.1 - 2.2e-24 86.3 0.0 2.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23710.1 - 5e-05 23.3 0.1 0.00015 21.7 0.1 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG23710.1 - 0.008 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AMP-binding PF00501.28 OAG23711.1 - 1.5e-94 317.0 0.0 2.3e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG23711.1 - 4.2e-05 24.4 0.1 0.00012 23.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 OAG23712.1 - 1.3e-15 57.6 0.0 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Xan_ur_permease PF00860.20 OAG23713.1 - 2.1e-67 227.5 32.4 3e-66 223.7 32.4 2.0 1 1 0 1 1 1 1 Permease family NDUF_B12 PF08122.12 OAG23713.1 - 0.034 14.2 0.2 0.63 10.1 0.0 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family FA_desaturase PF00487.24 OAG23715.1 - 6.1e-18 65.6 15.7 6.1e-18 65.6 15.7 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG23715.1 - 1.1e-16 60.7 0.1 2.1e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YndJ PF14158.6 OAG23715.1 - 0.0067 15.8 2.3 0.018 14.4 2.5 1.5 2 0 0 2 2 2 1 YndJ-like protein Tyr-DNA_phospho PF06087.12 OAG23716.1 - 6e-155 516.3 0.0 6.9e-155 516.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 OAG23716.1 - 0.0014 18.5 0.1 0.076 12.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.19 OAG23717.1 - 8.6e-18 64.3 5.2 1e-17 64.1 5.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UPF0223 PF05256.12 OAG23717.1 - 0.022 15.1 0.6 0.076 13.4 0.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0223) GalP_UDP_transf PF01087.22 OAG23718.1 - 3.3e-69 233.0 0.0 1.4e-68 231.0 0.0 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAG23718.1 - 1.4e-59 200.5 0.1 5.5e-59 198.6 0.1 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 OAG23718.1 - 0.014 16.1 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 HIT domain DcpS_C PF11969.8 OAG23718.1 - 0.026 15.0 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Yip1 PF04893.17 OAG23719.1 - 8.2e-13 48.4 13.0 1.3e-12 47.8 13.0 1.4 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 OAG23720.1 - 9.3e-16 58.2 0.1 1.6e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain COesterase PF00135.28 OAG23722.1 - 1.7e-89 301.0 0.0 9.3e-89 298.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG23722.1 - 1.5e-11 44.5 0.4 8.1e-11 42.2 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG23722.1 - 0.035 14.7 3.5 0.04 14.5 2.3 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family SET PF00856.28 OAG23723.1 - 7.6e-08 32.9 0.4 3e-07 31.0 0.0 2.2 2 1 0 2 2 2 1 SET domain PHD PF00628.29 OAG23723.1 - 7.3e-05 22.6 10.0 0.00015 21.6 10.0 1.5 1 0 0 1 1 1 1 PHD-finger VSP PF03302.13 OAG23724.1 - 0.00045 19.2 0.3 0.00045 19.2 0.3 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein PAS_3 PF08447.12 OAG23725.1 - 1.8e-11 44.2 0.0 3.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OAG23725.1 - 8.4e-06 25.9 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OAG23725.1 - 1.5e-05 25.2 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG23725.1 - 0.0003 20.8 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAG23725.1 - 0.0008 19.6 0.0 0.65 10.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold WD40 PF00400.32 OAG23726.1 - 1.4e-10 41.5 9.8 0.00021 22.0 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG23726.1 - 0.021 15.1 0.3 2.7 8.4 0.0 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Autotransporter PF03797.19 OAG23726.1 - 0.038 13.6 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Autotransporter beta-domain Nup160 PF11715.8 OAG23726.1 - 0.08 11.6 0.2 0.77 8.3 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PAN_4 PF14295.6 OAG23730.1 - 0.013 15.4 1.1 6.6 6.7 0.1 2.8 2 0 0 2 2 2 0 PAN domain Toxin_5 PF05294.13 OAG23730.1 - 2.6 8.6 5.1 19 5.8 0.1 3.4 3 0 0 3 3 3 0 Scorpion short toxin Abhydrolase_6 PF12697.7 OAG23731.1 - 6.9e-11 43.2 0.0 9.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAG23731.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAG23731.1 - 0.0022 17.3 0.0 0.0083 15.4 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 OAG23731.1 - 0.0067 16.0 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OAG23731.1 - 0.029 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG23731.1 - 0.045 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CFEM PF05730.11 OAG23732.1 - 6.3e-08 32.6 6.4 7.8e-08 32.3 6.4 1.1 1 0 0 1 1 1 1 CFEM domain DUF4148 PF13663.6 OAG23732.1 - 1.1 9.4 3.6 0.93 9.7 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) zf-H2C2_2 PF13465.6 OAG23733.1 - 5.2e-09 36.1 17.6 6.6e-05 23.1 3.7 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG23733.1 - 2.1e-08 34.2 14.2 0.00047 20.4 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG23733.1 - 0.019 15.2 0.4 0.056 13.7 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG23733.1 - 0.043 14.7 21.0 0.054 14.4 3.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAG23733.1 - 0.12 13.0 2.3 0.24 12.1 0.2 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAG23733.1 - 9.8 6.0 14.2 3.5 7.5 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad51 PF08423.11 OAG23735.1 - 2.8e-10 39.9 0.0 5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 OAG23735.1 - 1.6e-06 27.6 0.0 4.9e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 OAG23735.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OAG23735.1 - 6e-05 22.6 0.0 0.0005 19.6 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 OAG23735.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 OAG23735.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MOSC PF03473.17 OAG23736.1 - 3e-23 82.3 0.0 4.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG23736.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3425 PF11905.8 OAG23737.1 - 8.3e-13 48.4 5.7 6.6e-12 45.5 5.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Helo_like_N PF17111.5 OAG23738.1 - 6.8e-08 32.1 3.5 1.7e-07 30.8 3.5 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_12 PF13424.6 OAG23738.1 - 0.00055 20.2 2.5 0.12 12.7 1.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat CorA PF01544.18 OAG23738.1 - 0.0021 17.4 1.8 0.87 8.8 0.7 2.6 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2379 PF09543.10 OAG23738.1 - 0.0078 16.4 0.8 1.8 8.8 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2379) TPR_2 PF07719.17 OAG23738.1 - 0.03 14.4 0.1 18 5.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RecG_N PF17190.4 OAG23738.1 - 0.044 14.5 0.1 0.29 11.9 0.1 2.4 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF5082 PF16888.5 OAG23738.1 - 0.075 13.3 1.9 0.23 11.7 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DHR10 PF18595.1 OAG23738.1 - 0.085 12.9 1.7 0.25 11.4 0.8 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Ras PF00071.22 OAG23739.1 - 2.2e-32 111.9 0.0 2.7e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG23739.1 - 2.8e-14 53.3 0.0 4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG23739.1 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OAG23739.1 - 0.0016 18.2 0.0 0.37 10.5 0.0 2.5 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OAG23739.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG23739.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase PhyH PF05721.13 OAG23740.1 - 3.4e-06 27.5 0.2 7.7e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.19 OAG23740.1 - 0.013 15.4 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain UPF0524 PF15823.5 OAG23742.1 - 0.15 11.4 1.1 0.34 10.3 1.1 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ribosomal_S25 PF03297.15 OAG23743.1 - 2.5e-37 127.1 4.6 2.7e-37 127.0 4.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 OAG23743.1 - 0.037 14.4 0.1 0.053 13.9 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.12 OAG23743.1 - 0.052 13.3 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 OAG23743.1 - 0.056 13.4 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 HTH domain Cyt-b5 PF00173.28 OAG23744.1 - 6.7e-10 39.0 0.0 9.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 OAG23745.1 - 1.6e-71 240.4 0.0 2.1e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OAG23745.1 - 4.1e-05 23.1 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG23745.1 - 0.0013 18.8 0.0 0.0039 17.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG23745.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAG23745.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG23745.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAG23745.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OAG23745.1 - 0.066 13.2 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2834 PF11196.8 OAG23746.1 - 0.00055 20.2 12.0 0.43 11.0 1.9 4.3 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Na_H_antiport_1 PF06965.12 OAG23746.1 - 0.012 14.5 1.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 0 Na+/H+ antiporter 1 BCNT PF07572.12 OAG23747.1 - 5.9e-23 80.7 0.4 1.2e-22 79.8 0.4 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 OAG23747.1 - 7.1 4.8 7.4 7.8 4.7 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RdRP PF05183.12 OAG23748.1 - 1.7e-128 429.8 0.0 2.3e-128 429.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase TCTP PF00838.17 OAG23749.1 - 3.1e-68 229.3 3.6 3.5e-68 229.1 3.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Chordopox_A33R PF05966.12 OAG23749.1 - 0.029 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein FA_hydroxylase PF04116.13 OAG23750.1 - 9.7e-21 74.5 10.7 9.7e-21 74.5 10.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily KptA_kDCL PF18176.1 OAG23750.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Methyltransf_28 PF02636.17 OAG23752.1 - 6.9e-76 255.3 0.0 8.5e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 OAG23752.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Pkinase PF00069.25 OAG23753.1 - 4.3e-64 216.4 0.0 5.8e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23753.1 - 7.6e-26 90.9 0.0 1.5e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG23753.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG23753.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAG23753.1 - 0.031 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG23753.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF1679 PF07914.11 OAG23753.1 - 0.16 10.8 0.0 0.41 9.5 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) NARP1 PF12569.8 OAG23753.1 - 1.5 7.7 10.5 2.1 7.1 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Profilin PF00235.19 OAG23754.1 - 5.3e-40 136.6 0.3 5.8e-40 136.5 0.3 1.0 1 0 0 1 1 1 1 Profilin HeLo PF14479.6 OAG23755.1 - 1.4e-24 87.1 2.6 2.4e-24 86.3 2.6 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 OAG23755.1 - 0.0065 15.9 0.0 0.038 13.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain GyrB_insert PF18053.1 OAG23755.1 - 0.028 14.3 0.7 0.063 13.2 0.7 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain Metallophos PF00149.28 OAG23756.1 - 2.3e-13 51.1 0.3 6e-13 49.8 0.1 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG23756.1 - 8.2e-08 32.6 0.1 1.3e-06 28.8 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S11 PF00411.19 OAG23757.1 - 1.4e-46 157.4 1.6 1.8e-46 157.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.17 OAG23758.1 - 4e-16 58.8 0.0 5.7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 OAG23758.1 - 4.1e-08 33.6 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG23758.1 - 5.8e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG23758.1 - 9.3e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OAG23758.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAG23758.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OAG23758.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.20 OAG23758.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAG23758.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain LpxI_N PF17930.1 OAG23758.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 LpxI N-terminal domain Lactamase_B_2 PF12706.7 OAG23759.1 - 2.9e-32 111.8 0.0 1e-30 106.7 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG23759.1 - 1.9e-11 44.1 0.0 8.6e-11 42.0 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG23759.1 - 0.00036 20.6 2.9 0.78 9.7 1.8 3.1 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Cyclin PF08613.11 OAG23761.1 - 7.1e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG23761.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L30 PF00327.20 OAG23762.1 - 1.2e-19 70.0 2.5 2.1e-19 69.1 2.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 OAG23762.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter DAHP_synth_1 PF00793.20 OAG23764.1 - 2.5e-103 344.7 0.1 3.1e-103 344.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SMC_Nse1 PF07574.13 OAG23765.1 - 6.1e-59 199.2 4.4 7.5e-59 198.9 4.4 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OAG23765.1 - 2.2e-14 53.5 8.4 4e-14 52.6 8.4 1.5 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.6 OAG23765.1 - 0.012 15.7 1.8 0.025 14.7 1.8 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain RepL PF05732.11 OAG23765.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) zf-HC5HC2H PF13771.6 OAG23765.1 - 0.034 14.4 5.1 0.096 12.9 5.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 OAG23765.1 - 0.2 11.9 3.6 0.44 10.7 3.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 OAG23765.1 - 2.3 8.6 6.1 3.8 7.9 6.1 1.4 1 0 0 1 1 1 0 Ring finger domain FYDLN_acid PF09538.10 OAG23765.1 - 3.2 8.5 8.6 0.41 11.4 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.22 OAG23765.1 - 8.5 6.3 7.5 0.74 9.8 1.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Got1 PF04178.12 OAG23766.1 - 2.2e-14 53.8 14.6 2.8e-14 53.5 14.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family C166 PF17615.2 OAG23766.1 - 0.005 17.0 2.7 0.0068 16.6 2.7 1.1 1 0 0 1 1 1 1 Family of unknown function Dicistro_VP4 PF11492.8 OAG23766.1 - 0.08 12.9 0.2 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 YL1_C PF08265.11 OAG23767.1 - 2.6e-16 59.0 0.2 4.1e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DDE_Tnp_1_5 PF13737.6 OAG23768.1 - 0.027 14.8 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DASH_Dad4 PF08650.10 OAG23769.1 - 3.7e-19 68.5 2.5 4.3e-19 68.3 2.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 HOK_GEF PF01848.16 OAG23769.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Hok/gef family Actin PF00022.19 OAG23770.1 - 2.9e-52 177.6 0.0 2.4e-26 92.3 0.0 2.4 1 1 0 2 2 2 2 Actin DUF3040 PF11239.8 OAG23770.1 - 0.06 13.6 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Y_phosphatase PF00102.27 OAG23771.1 - 1.4e-61 208.1 0.7 4e-32 111.7 0.1 2.9 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAG23771.1 - 9.1e-12 45.4 0.0 1.1e-10 42.0 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 OAG23771.1 - 0.031 14.1 0.1 0.077 12.8 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAG23771.1 - 0.042 13.8 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipase_3 PF01764.25 OAG23772.1 - 3.6e-05 23.7 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 OAG23772.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) VPS9 PF02204.18 OAG23773.1 - 5.4e-25 87.6 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG23773.1 - 0.052 13.9 0.0 0.37 11.1 0.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Fungal_TACC PF12709.7 OAG23774.1 - 2.5e-08 34.2 20.0 2.6e-08 34.2 4.8 4.1 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 OAG23774.1 - 7.2e-06 25.6 35.6 0.002 17.5 9.7 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 OAG23774.1 - 3.4e-05 24.0 14.0 3.4e-05 24.0 14.0 3.6 3 1 0 3 3 2 1 Tropomyosin like GBR2_CC PF18455.1 OAG23774.1 - 0.11 12.6 0.6 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Csm1_N PF18504.1 OAG23774.1 - 0.21 11.9 23.8 0.73 10.2 0.5 5.0 4 1 0 4 4 4 0 Csm1 N-terminal domain Baculo_PEP_C PF04513.12 OAG23774.1 - 1.4 9.0 9.2 2.3 8.3 0.3 3.7 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 OAG23774.1 - 3 7.6 18.2 0.61 9.9 0.1 3.8 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 OAG23774.1 - 4.4 7.3 44.2 0.86 9.6 8.5 4.2 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 OAG23774.1 - 5 7.5 48.4 0.21 12.0 17.2 3.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TSC22 PF01166.18 OAG23774.1 - 6.4 7.2 8.9 15 6.0 0.9 3.7 3 1 1 4 4 4 0 TSC-22/dip/bun family FAM184 PF15665.5 OAG23774.1 - 8.2 6.1 38.7 2.5 7.8 21.8 2.8 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B GAS PF13851.6 OAG23774.1 - 9.2 5.5 35.2 0.04 13.3 1.3 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Mitofilin PF09731.9 OAG23775.1 - 3 6.6 5.2 3.8 6.2 5.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Vta1 PF04652.16 OAG23776.1 - 0.088 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Vta1 like Iso_dh PF00180.20 OAG23777.1 - 3.5e-122 407.9 0.0 4e-122 407.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase VWA PF00092.28 OAG23780.1 - 2.1e-08 34.6 0.0 8.1e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG23780.1 - 8.4e-06 26.4 0.0 2.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OAG23780.1 - 0.00028 21.1 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus HET PF06985.11 OAG23781.1 - 1.2e-28 100.3 1.1 2.1e-28 99.5 1.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Anoctamin PF04547.12 OAG23782.1 - 2.9e-112 375.8 3.8 3.6e-112 375.5 3.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PAP_assoc PF03828.19 OAG23783.1 - 1.2e-09 38.2 0.0 2.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG23783.1 - 2.6e-07 30.8 0.0 7.5e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Pam16 PF03656.13 OAG23784.1 - 3.4e-30 104.6 0.3 4.1e-30 104.4 0.3 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 OAG23785.1 - 8.8e-96 321.1 0.7 1.1e-95 320.8 0.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Amidase PF01425.21 OAG23786.1 - 1.2e-110 370.6 0.1 1.4e-110 370.3 0.1 1.0 1 0 0 1 1 1 1 Amidase Bud13 PF09736.9 OAG23787.1 - 5.9e-47 159.7 10.2 5.9e-47 159.7 10.2 3.3 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 OAG23787.1 - 0.041 14.2 2.3 0.074 13.4 2.3 1.6 1 0 0 1 1 1 0 SPATIAL TMEM214 PF10151.9 OAG23787.1 - 6.1 5.2 8.8 10 4.4 8.8 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DNA_binding_1 PF01035.20 OAG23788.1 - 1.5e-23 82.7 0.0 2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_3 PF07859.13 OAG23791.1 - 2.7e-44 151.6 0.2 4.3e-30 105.2 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OAG23791.1 - 1.1e-07 31.1 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG23791.1 - 0.0011 18.5 0.0 0.032 13.7 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAG23791.1 - 0.064 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG23791.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase adh_short PF00106.25 OAG23792.1 - 9.6e-23 80.7 0.0 5e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23792.1 - 2.7e-10 40.2 0.0 1.6e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23792.1 - 6.1e-07 29.5 0.0 9.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG23792.1 - 8.4e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG23792.1 - 0.056 12.6 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG23792.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein AAA PF00004.29 OAG23795.1 - 4.4e-59 198.7 0.0 3e-43 147.4 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG23795.1 - 2e-16 59.5 0.3 1.1e-08 34.7 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 OAG23795.1 - 1.7e-11 44.3 0.0 7.5e-07 29.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG23795.1 - 5.1e-11 43.3 1.7 0.02 15.2 0.0 4.5 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAG23795.1 - 8.5e-08 32.6 0.9 0.05 13.9 0.0 4.2 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 OAG23795.1 - 1e-06 29.0 0.0 0.0013 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OAG23795.1 - 7.3e-06 26.0 0.0 0.22 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 OAG23795.1 - 9.4e-06 25.8 0.0 0.00057 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OAG23795.1 - 0.00012 21.6 0.0 0.58 9.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG23795.1 - 0.00017 22.0 0.0 0.44 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OAG23795.1 - 0.00028 20.4 0.0 0.28 10.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 OAG23795.1 - 0.00061 19.2 0.0 0.41 10.0 0.0 3.2 2 1 1 3 3 3 1 Bacterial TniB protein RuvB_N PF05496.12 OAG23795.1 - 0.00064 19.5 0.0 0.0049 16.6 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain PNPase PF03726.14 OAG23795.1 - 0.00084 19.8 0.1 0.0029 18.1 0.1 1.9 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain TIP49 PF06068.13 OAG23795.1 - 0.0011 18.2 0.0 0.0056 15.9 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 OAG23795.1 - 0.0013 18.7 0.0 1.4 8.9 0.0 3.5 3 1 0 3 3 3 1 NACHT domain Vps4_C PF09336.10 OAG23795.1 - 0.0014 18.6 0.1 0.37 10.8 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 OAG23795.1 - 0.0016 18.6 0.0 0.063 13.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 OAG23795.1 - 0.0039 17.5 0.0 0.48 10.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 OAG23795.1 - 0.004 16.5 0.0 0.083 12.2 0.0 2.7 2 1 1 3 3 3 1 KaiC CDC48_N PF02359.18 OAG23795.1 - 0.0052 16.9 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 OAG23795.1 - 0.0055 16.3 1.1 9.2 5.8 0.1 3.6 2 2 2 4 4 4 0 AAA domain AAA_23 PF13476.6 OAG23795.1 - 0.013 16.1 0.4 1.2 9.6 0.3 3.6 3 2 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OAG23795.1 - 0.018 14.8 0.0 4.7 6.9 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OAG23795.1 - 0.022 14.5 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 OAG23795.1 - 0.028 14.3 0.1 2.3 8.1 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain ATPase_2 PF01637.18 OAG23795.1 - 0.031 14.2 0.0 21 4.9 0.0 3.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAG23795.1 - 0.084 12.6 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG23795.1 - 0.16 12.5 0.0 5.7 7.4 0.0 2.7 2 0 0 2 2 2 0 ABC transporter EAP30 PF04157.16 OAG23797.1 - 2.1e-62 210.5 0.0 2.3e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.11 OAG23798.1 - 6.2e-99 331.7 0.1 1e-98 331.1 0.1 1.2 1 0 0 1 1 1 1 AAR2 protein DUF4994 PF16385.5 OAG23798.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function zf-LITAF-like PF10601.9 OAG23799.1 - 7.8e-22 77.3 7.8 1e-21 76.9 7.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PAP2 PF01569.21 OAG23800.1 - 1.9e-24 85.9 2.2 1.9e-24 85.9 2.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OAG23800.1 - 3.8 8.1 5.9 0.53 10.8 0.8 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal AMP-binding PF00501.28 OAG23802.1 - 4.2e-295 977.7 0.0 2.4e-79 266.9 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 OAG23802.1 - 1e-167 558.5 0.0 1.6e-44 152.3 0.0 5.2 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 OAG23802.1 - 1e-45 153.9 6.5 8.4e-11 42.1 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG23802.1 - 3.9e-20 72.6 0.0 0.00077 20.4 0.0 5.5 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 OAG23802.1 - 0.00042 20.2 0.2 15 5.2 0.0 4.6 4 0 0 4 4 4 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AAA_lid_7 PF17867.1 OAG23802.1 - 0.12 12.6 0.0 0.55 10.4 0.0 2.2 1 0 0 1 1 1 0 Midasin AAA lid domain ABC_membrane PF00664.23 OAG23803.1 - 7.4e-81 271.8 24.3 2.1e-44 152.2 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG23803.1 - 7.9e-69 230.5 0.0 5e-35 121.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG23803.1 - 5.4e-13 48.9 0.6 0.00024 20.6 0.8 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG23803.1 - 6.1e-08 33.2 3.4 0.0031 17.9 0.0 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAG23803.1 - 2.8e-07 30.9 0.2 0.0015 18.8 0.0 3.8 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG23803.1 - 3.5e-07 29.9 0.5 0.015 15.0 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAG23803.1 - 1.1e-06 28.0 0.0 0.0082 15.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 OAG23803.1 - 1.2e-06 28.6 1.4 0.27 11.0 0.1 4.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG23803.1 - 5.8e-06 26.3 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAG23803.1 - 1.4e-05 25.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 OAG23803.1 - 2.4e-05 23.3 0.3 0.082 11.7 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_7 PF12775.7 OAG23803.1 - 4.8e-05 22.9 0.0 0.071 12.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region APS_kinase PF01583.20 OAG23803.1 - 0.00053 19.9 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA PF00004.29 OAG23803.1 - 0.00089 19.7 0.0 2.4 8.6 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG23803.1 - 0.0012 19.0 0.0 0.42 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG23803.1 - 0.0017 18.4 0.2 1.7 8.8 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAG23803.1 - 0.0024 17.6 0.1 1.7 8.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAG23803.1 - 0.0041 17.7 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG23803.1 - 0.0062 16.5 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OAG23803.1 - 0.009 15.2 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit IstB_IS21 PF01695.17 OAG23803.1 - 0.0091 15.7 0.0 2.5 7.8 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 OAG23803.1 - 0.024 14.2 0.4 1.3 8.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 OAG23803.1 - 0.034 14.4 5.0 0.75 10.1 0.5 4.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit YuiB PF14068.6 OAG23803.1 - 0.037 14.6 0.4 0.037 14.6 0.4 3.2 3 1 0 3 3 1 0 Putative membrane protein DUF87 PF01935.17 OAG23803.1 - 0.068 13.3 0.0 8.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 OAG23803.1 - 0.074 13.6 0.0 0.81 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG23803.1 - 0.089 12.5 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OAG23803.1 - 0.12 12.1 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 OAG23803.1 - 0.18 12.2 0.0 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase K_oxygenase PF13434.6 OAG23804.1 - 1.7e-101 339.8 0.0 2.9e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG23804.1 - 2.4e-07 30.3 0.0 2.4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 OAG23805.1 - 8.5e-50 169.6 0.0 1.9e-49 168.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23805.1 - 2e-23 83.0 0.8 3.1e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG23805.1 - 0.0049 16.8 0.0 0.0049 16.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG23805.1 - 0.011 15.3 0.2 0.011 15.3 0.2 2.1 2 1 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 OAG23805.1 - 0.73 9.4 3.2 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase TFIIA PF03153.13 OAG23805.1 - 1.6 8.7 50.4 3.7 7.4 15.0 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.12 OAG23806.1 - 1.6e-172 575.0 29.8 1.6e-172 575.0 29.8 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAG23806.1 - 6.5e-15 55.5 0.0 5.8e-14 52.5 0.0 2.8 1 1 0 1 1 1 1 PCI domain Per1 PF04080.13 OAG23807.1 - 2.1e-105 352.1 9.1 2.5e-105 351.8 9.1 1.1 1 0 0 1 1 1 1 Per1-like family DUF1027 PF06265.11 OAG23807.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Methyltransf_23 PF13489.6 OAG23809.1 - 6.8e-13 48.8 0.0 9.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG23809.1 - 2.9e-10 40.7 0.0 5.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG23809.1 - 8.1e-10 39.3 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG23809.1 - 2.2e-09 37.3 0.0 4.9e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG23809.1 - 5.8e-09 36.5 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG23809.1 - 0.0032 16.8 0.0 0.0062 15.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 OAG23809.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Phage_T7_Capsid PF05396.11 OAG23809.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Methyltransf_32 PF13679.6 OAG23809.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ALS2CR11 PF15729.5 OAG23810.1 - 0.13 11.4 0.9 0.19 10.9 0.9 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 TPR_10 PF13374.6 OAG23811.1 - 1.3e-12 47.2 5.1 8.9e-05 22.2 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23811.1 - 1.7e-09 37.9 3.4 0.00012 22.3 2.3 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG23811.1 - 0.0027 17.7 1.2 0.43 10.8 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23811.1 - 0.0052 17.5 2.4 0.087 13.7 1.3 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG23811.1 - 0.016 15.9 4.6 0.15 12.8 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 OAG23811.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 OAG23811.1 - 0.13 12.5 0.6 0.48 10.8 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG23811.1 - 0.22 11.6 1.7 0.69 10.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG23811.1 - 1.1 9.3 3.0 0.42 10.5 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec63 PF02889.16 OAG23812.1 - 6.4e-134 445.0 0.0 1.5e-81 273.4 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAG23812.1 - 7.7e-52 175.6 0.0 1.5e-26 93.2 0.5 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 OAG23812.1 - 8.7e-21 74.7 0.0 4.1e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG23812.1 - 5.4e-16 58.9 0.0 2.4e-06 27.9 0.0 3.9 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG23812.1 - 3.7e-07 30.0 0.1 0.0037 17.0 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAG23812.1 - 9.7e-07 29.1 1.0 0.076 13.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG23812.1 - 9.5e-06 26.0 0.5 0.001 19.4 0.8 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 OAG23812.1 - 0.00065 19.9 0.0 0.002 18.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain TniB PF05621.11 OAG23812.1 - 0.77 9.1 3.4 15 4.9 0.1 3.8 5 0 0 5 5 5 0 Bacterial TniB protein TetR_C_11 PF16859.5 OAG23812.1 - 1.3 9.4 4.3 1.8 8.9 1.2 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Synaptobrevin PF00957.21 OAG23813.1 - 9.8e-15 54.1 0.6 1.5e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG23813.1 - 3.2e-14 52.7 0.0 6.9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain RST PF12174.8 OAG23813.1 - 0.015 15.2 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Cgr1 PF03879.14 OAG23813.1 - 0.17 12.3 0.3 0.31 11.4 0.3 1.4 1 0 0 1 1 1 0 Cgr1 family TPR_10 PF13374.6 OAG23815.1 - 8.1e-39 130.5 25.9 9.6e-07 28.5 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23815.1 - 9.9e-35 118.7 22.6 1.9e-08 34.5 4.3 6.2 3 1 3 6 6 6 6 Tetratricopeptide repeat SesA PF17107.5 OAG23815.1 - 1.3e-13 51.2 0.3 1.3e-13 51.2 0.3 2.3 3 0 0 3 3 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_2 PF07719.17 OAG23815.1 - 4.5e-08 32.6 5.6 0.19 11.9 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG23815.1 - 5.3e-06 26.0 0.1 1.2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_1 PF00515.28 OAG23815.1 - 1.3e-05 24.8 9.4 0.54 10.2 0.2 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23815.1 - 2e-05 24.4 5.4 8.5 6.9 0.1 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG23815.1 - 3.6e-05 24.2 12.1 0.00016 22.1 0.9 4.5 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG23815.1 - 0.00044 20.6 7.3 0.039 14.6 0.1 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23815.1 - 0.00055 20.5 16.7 4 8.5 0.1 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG23815.1 - 0.00067 18.9 0.1 0.032 13.4 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain TPR_MalT PF17874.1 OAG23815.1 - 0.0007 19.1 12.8 0.0067 15.8 8.2 2.8 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 OAG23815.1 - 0.0029 17.5 13.7 0.39 10.9 0.2 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG23815.1 - 0.022 15.4 10.7 4 8.2 0.0 5.5 4 2 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG23815.1 - 0.027 14.7 3.7 7.7 6.8 0.9 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 tRNA_bind_3 PF17176.4 OAG23815.1 - 0.027 14.7 0.1 0.082 13.2 0.1 1.8 1 0 0 1 1 1 0 tRNA-binding domain AAA_25 PF13481.6 OAG23815.1 - 0.12 11.9 0.3 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF957 PF06117.11 OAG23815.1 - 0.44 10.2 2.2 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) TPR_11 PF13414.6 OAG23815.1 - 4.5 7.0 7.9 11 5.8 0.0 3.5 3 0 0 3 3 3 0 TPR repeat UDPG_MGDP_dh_N PF03721.14 OAG23816.1 - 2.1e-54 183.9 0.0 3.4e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAG23816.1 - 7.4e-33 113.1 0.5 8.2e-28 96.9 0.0 2.7 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAG23816.1 - 4.8e-29 100.4 0.0 8.8e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.23 OAG23816.1 - 0.0067 16.5 0.1 5.5 7.1 0.0 3.4 2 1 1 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG23816.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pox_A28 PF04584.14 OAG23816.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A28 family Sacchrp_dh_NADP PF03435.18 OAG23816.1 - 0.14 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M16_C PF05193.21 OAG23816.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain TPT PF03151.16 OAG23817.1 - 8.5e-36 123.8 15.2 9.8e-36 123.6 15.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG23817.1 - 8.5e-12 44.9 18.7 1.3e-11 44.2 18.7 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG23817.1 - 0.028 14.6 33.5 0.18 12.0 16.3 2.5 2 1 0 2 2 2 0 EamA-like transporter family Herpes_UL46 PF03387.14 OAG23822.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL46 protein MFS_1 PF07690.16 OAG23823.1 - 6.1e-22 78.0 44.4 6.1e-22 78.0 44.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Polyketide_cyc2 PF10604.9 OAG23824.1 - 4.1e-07 30.4 0.0 4.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans_2 PF11951.8 OAG23825.1 - 2.3e-10 39.8 0.1 7.9e-10 38.1 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 OAG23826.1 - 8.3e-25 87.4 33.2 1.4e-24 86.7 33.2 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4131 PF13567.6 OAG23826.1 - 0.63 9.7 9.2 2.5 7.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Actin PF00022.19 OAG23827.1 - 2.8e-75 253.5 0.0 1.9e-74 250.7 0.0 2.0 1 1 0 1 1 1 1 Actin Ribosomal_L50 PF10501.9 OAG23827.1 - 6.2e-15 55.3 0.1 1.6e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S FAM176 PF14851.6 OAG23828.1 - 0.11 12.1 2.3 0.18 11.5 2.3 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 OAG23828.1 - 1.4 9.4 4.9 0.77 10.2 2.7 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAG23828.1 - 4.3 6.6 5.9 7.4 5.8 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein SH3_3 PF08239.11 OAG23829.1 - 0.024 14.9 0.2 0.035 14.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain UQ_con PF00179.26 OAG23830.1 - 6.1e-13 48.6 0.3 1.2e-12 47.6 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG23830.1 - 0.0071 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain Cornifin PF02389.15 OAG23832.1 - 3.2e-05 24.2 0.1 5.4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Cornifin (SPRR) family Pro_Al_protease PF02983.14 OAG23834.1 - 2.6e-12 46.6 1.0 2.6e-12 46.6 1.0 2.5 2 1 0 2 2 2 1 Alpha-lytic protease prodomain HTH_AsnC-type PF13404.6 OAG23834.1 - 0.024 14.4 1.6 0.23 11.3 0.1 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Asp_protease PF09668.10 OAG23834.1 - 0.2 11.4 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zinc_ribbon_5 PF13719.6 OAG23835.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain SnoaL PF07366.12 OAG23836.1 - 0.0013 18.5 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase PIN_4 PF13638.6 OAG23837.1 - 0.39 11.0 2.0 0.95 9.8 2.0 1.6 1 0 0 1 1 1 0 PIN domain Chordopox_L2 PF05803.12 OAG23838.1 - 0.0069 16.2 0.3 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 Chordopoxvirus L2 protein Colicin_Pyocin PF01320.18 OAG23838.1 - 0.048 13.8 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein DUF3433 PF11915.8 OAG23839.1 - 1.8e-26 92.4 13.4 1.5e-16 60.6 2.3 4.3 5 1 0 5 5 5 2 Protein of unknown function (DUF3433) zf_C2H2_10 PF18414.1 OAG23840.1 - 0.066 12.8 0.2 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger RAP1 PF07218.11 OAG23840.1 - 1 7.6 4.2 1.4 7.1 4.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FKBP_C PF00254.28 OAG23842.1 - 1.3e-21 76.7 0.0 1.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 OAG23843.1 - 6.3e-14 52.6 1.3 3.2e-13 50.3 1.5 2.0 2 1 0 2 2 2 1 PHP domain AIG2_2 PF13772.6 OAG23844.1 - 4e-07 30.3 0.2 1.7e-06 28.3 0.1 2.0 2 1 0 2 2 2 1 AIG2-like family GGACT PF06094.12 OAG23844.1 - 2.8e-06 27.9 0.0 4.5e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like BAR_2 PF10455.9 OAG23845.1 - 8e-64 215.5 0.8 1.2e-63 215.0 0.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAG23845.1 - 3.2e-20 72.8 3.6 4.6e-19 69.0 3.6 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OAG23845.1 - 0.0037 17.0 0.3 0.023 14.4 0.1 2.3 2 1 0 2 2 2 1 BAR domain of APPL family DUF2564 PF10819.8 OAG23845.1 - 4.2 7.8 6.9 3.2 8.2 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) Zn_clus PF00172.18 OAG23846.1 - 1.9e-07 31.1 11.6 3.1e-07 30.4 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.10 OAG23846.1 - 0.36 10.1 12.5 0.53 9.6 12.5 1.2 1 0 0 1 1 1 0 BUD22 zf-RING_2 PF13639.6 OAG23847.1 - 8.9e-11 41.9 8.6 1.3e-10 41.4 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG23847.1 - 1.2e-08 35.0 6.4 2.1e-08 34.3 6.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG23847.1 - 2.3e-06 27.3 8.4 3.6e-06 26.7 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG23847.1 - 6.5e-05 22.6 7.5 0.00012 21.8 7.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OAG23847.1 - 7.8e-05 22.6 2.9 0.00014 21.8 2.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG23847.1 - 8.1e-05 22.4 8.1 0.00012 21.8 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG23847.1 - 0.0011 18.9 6.5 0.0016 18.3 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAG23847.1 - 0.0011 18.6 6.4 0.0018 17.9 6.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAG23847.1 - 0.0036 17.1 6.3 0.0061 16.4 6.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG23847.1 - 0.044 13.6 5.3 0.076 12.9 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) fn2 PF00040.19 OAG23847.1 - 0.11 12.8 0.5 0.22 11.8 0.0 1.7 2 0 0 2 2 1 0 Fibronectin type II domain zf-RING_UBOX PF13445.6 OAG23847.1 - 0.14 12.2 7.2 0.27 11.3 7.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 OAG23847.1 - 0.19 11.8 3.1 0.34 11.0 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 OAG23847.1 - 0.31 10.9 6.9 0.5 10.2 6.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAG23847.1 - 0.36 11.0 4.7 0.63 10.2 4.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 OAG23847.1 - 0.61 9.9 3.6 1.1 9.1 3.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OAG23847.1 - 0.69 10.1 8.9 1.1 9.4 8.9 1.3 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 OAG23847.1 - 0.86 10.0 5.1 1.5 9.2 5.1 1.4 1 0 0 1 1 1 0 RING-like domain RNA_pol_I_TF PF04090.12 OAG23848.1 - 1.3e-08 34.6 0.0 1.1e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Rib_recp_KP_reg PF05104.12 OAG23848.1 - 0.97 10.5 6.5 1.7 9.7 6.5 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region TPR_6 PF13174.6 OAG23848.1 - 1.1 10.0 3.4 11 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SASRP1 PF15160.6 OAG23848.1 - 1.8 8.2 4.0 16 5.1 0.9 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 AltA1 PF16541.5 OAG23849.1 - 0.013 16.3 0.3 0.026 15.4 0.3 1.5 1 1 0 1 1 1 0 Alternaria alternata allergen 1 Syntaxin-18_N PF10496.9 OAG23850.1 - 4.3e-10 39.7 0.3 2.3e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAG23850.1 - 0.0012 18.8 0.0 0.004 17.1 0.0 1.9 1 0 0 1 1 1 1 SNARE domain Jnk-SapK_ap_N PF09744.9 OAG23850.1 - 0.0093 16.2 9.4 0.56 10.4 0.1 2.4 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 KELK PF15796.5 OAG23850.1 - 0.026 15.0 13.2 0.9 10.0 3.4 3.5 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2935 PF11155.8 OAG23850.1 - 0.27 11.6 2.9 0.25 11.7 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) SIM_C PF06621.12 OAG23850.1 - 4 7.4 8.7 5.9 6.8 0.9 2.6 1 1 2 3 3 3 0 Single-minded protein C-terminus Aminotran_1_2 PF00155.21 OAG23851.1 - 8.6e-86 288.4 0.0 1e-85 288.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Retrotran_gag_3 PF14244.6 OAG23852.1 - 1e-05 25.2 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 OAG23852.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Metallophos PF00149.28 OAG23853.1 - 4.4e-11 43.7 2.5 9e-11 42.6 2.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG23853.1 - 7.4e-07 29.5 0.0 6.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Coatomer_WDAD PF04053.14 OAG23854.1 - 6.1e-171 569.4 0.0 1.2e-170 568.3 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OAG23854.1 - 2.4e-37 126.3 1.8 2.8e-06 27.9 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 OAG23854.1 - 0.00035 19.3 1.7 0.17 10.5 0.1 3.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OAG23854.1 - 0.0049 16.9 0.0 3 7.9 0.0 4.0 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 OAG23854.1 - 0.041 13.7 0.3 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS WD40_like PF17005.5 OAG23854.1 - 0.067 12.5 0.0 14 4.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain MetallophosC PF16370.5 OAG23854.1 - 0.13 12.5 0.4 0.98 9.6 0.0 2.5 2 1 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase TPR_4 PF07721.14 OAG23854.1 - 1.3 9.9 3.0 29 5.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 OAG23855.1 - 4.4e-36 124.2 0.0 1e-35 123.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG23855.1 - 5.1e-07 29.4 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG23855.1 - 2.8e-05 24.6 1.1 0.0005 20.5 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OAG23855.1 - 2.9e-05 23.9 0.0 6.6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAG23855.1 - 6.3e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG23855.1 - 7e-05 22.9 0.1 0.0006 19.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG23855.1 - 0.00015 22.0 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAG23855.1 - 0.00024 21.4 0.7 0.0088 16.3 0.0 2.9 3 1 1 4 4 3 1 AAA domain AAA_33 PF13671.6 OAG23855.1 - 0.00036 20.7 0.1 0.0011 19.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 OAG23855.1 - 0.00066 19.3 0.0 0.034 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAG23855.1 - 0.00081 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OAG23855.1 - 0.00088 19.8 0.0 0.0034 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAG23855.1 - 0.0011 18.4 0.1 0.0023 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG23855.1 - 0.0016 18.8 0.0 0.0051 17.2 0.0 1.9 1 1 0 1 1 1 1 RNA helicase TniB PF05621.11 OAG23855.1 - 0.0027 17.1 0.0 2.6 7.4 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 OAG23855.1 - 0.0044 17.0 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OAG23855.1 - 0.0075 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAG23855.1 - 0.01 16.1 1.7 0.02 15.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 OAG23855.1 - 0.013 15.7 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 OAG23855.1 - 0.019 14.9 0.1 0.049 13.5 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 OAG23855.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OAG23855.1 - 0.034 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 OAG23855.1 - 0.037 14.5 0.0 0.087 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAG23855.1 - 0.044 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region CPT PF07931.12 OAG23855.1 - 0.063 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 OAG23855.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 OAG23855.1 - 0.11 12.4 0.8 0.27 11.1 0.0 2.0 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea Guanylate_kin PF00625.21 OAG23855.1 - 0.11 12.1 0.3 1.8 8.2 0.0 2.9 3 1 1 4 4 3 0 Guanylate kinase TsaE PF02367.17 OAG23855.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 OAG23855.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAG23855.1 - 0.16 11.1 0.1 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 OAG23855.1 - 0.66 10.1 0.0 0.66 10.1 0.0 2.5 3 0 0 3 3 2 0 Shikimate kinase AAA_11 PF13086.6 OAG23855.1 - 1.2 8.8 4.2 0.64 9.8 0.4 2.4 2 1 0 2 2 2 0 AAA domain TIM21 PF08294.11 OAG23856.1 - 3.8e-42 143.6 0.0 5.3e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 OAG23856.1 - 2.6e-07 30.4 0.0 9.4e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Acetyltransf_7 PF13508.7 OAG23857.1 - 1.2e-09 38.4 0.0 4.6e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG23857.1 - 8.2e-09 35.7 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG23857.1 - 5.9e-07 29.5 0.0 3.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG23857.1 - 0.0053 16.8 0.0 0.051 13.6 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3302 PF11742.8 OAG23857.1 - 0.022 14.9 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Arginase PF00491.21 OAG23858.1 - 1.5e-20 73.8 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family ThrE PF06738.12 OAG23859.1 - 3.1e-64 216.6 5.6 3.1e-64 216.6 5.6 2.6 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAG23859.1 - 8.5e-07 29.2 15.8 8.5e-07 29.2 15.8 2.8 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE bZIP_1 PF00170.21 OAG23860.1 - 3e-07 30.4 6.7 5e-07 29.7 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 OAG23860.1 - 0.0039 16.9 2.1 0.0057 16.4 1.8 1.3 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 OAG23860.1 - 0.0067 16.9 6.0 0.013 16.0 6.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor PspA_IM30 PF04012.12 OAG23860.1 - 0.01 15.5 4.3 0.014 15.0 4.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family BCAS2 PF05700.11 OAG23860.1 - 0.04 13.6 2.4 0.054 13.2 2.4 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3584 PF12128.8 OAG23860.1 - 0.05 11.1 4.3 0.06 10.9 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 OAG23860.1 - 0.11 11.8 4.3 0.15 11.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TIR-like PF10137.9 OAG23860.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain V_ATPase_I PF01496.19 OAG23860.1 - 0.37 8.7 0.7 0.45 8.4 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 OAG23860.1 - 0.52 10.4 12.6 2.4 8.3 12.6 1.9 1 1 0 1 1 1 0 Basic region leucine zipper Pet20 PF08692.10 OAG23861.1 - 0.097 13.4 0.1 0.12 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet20 BRO1 PF03097.18 OAG23863.1 - 6e-134 446.7 1.9 6e-134 446.7 1.9 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG23863.1 - 1.1e-80 271.2 11.7 2e-80 270.3 11.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 OAG23863.1 - 0.002 17.6 1.6 0.026 14.0 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF416) DUF2383 PF09537.10 OAG23863.1 - 0.052 13.9 4.6 4.9 7.5 0.3 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF2383) HeLo PF14479.6 OAG23863.1 - 0.75 9.6 7.8 0.075 12.9 1.6 2.4 2 1 0 2 2 2 0 Prion-inhibition and propagation DnaJ_C PF01556.18 OAG23864.1 - 6.1e-37 127.0 0.0 9.1e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG23864.1 - 8.7e-22 77.0 1.8 1.6e-21 76.2 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG23864.1 - 4.4e-08 33.4 21.2 1.1e-07 32.1 21.2 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OAG23864.1 - 2.8 8.0 7.9 23 5.0 6.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OAG23864.1 - 5.2 7.2 8.8 12 6.0 8.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon SAP30_Sin3_bdg PF13867.6 OAG23865.1 - 0.00017 21.8 0.0 0.049 14.0 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Glyco_hydro_61 PF03443.14 OAG23867.1 - 3.1e-56 190.6 0.2 3.8e-56 190.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 OAG23868.1 - 2.5e-36 125.0 0.0 1.4e-34 119.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23868.1 - 3.1e-29 102.2 0.0 6e-29 101.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23868.1 - 0.0022 17.9 0.7 0.029 14.3 0.7 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG23868.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG23868.1 - 0.072 12.9 1.1 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_3 PF00202.21 OAG23870.1 - 1.6e-104 349.8 0.0 1.9e-104 349.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG23870.1 - 0.0098 15.1 0.0 0.084 12.0 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Neisseria_PilC PF05567.11 OAG23870.1 - 0.063 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain NmrA PF05368.13 OAG23871.1 - 7.4e-38 130.4 0.1 9e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG23871.1 - 4.3e-14 52.8 0.0 6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG23871.1 - 3.7e-07 29.9 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG23871.1 - 0.00067 19.6 0.0 0.00096 19.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG23871.1 - 0.0027 16.9 0.1 0.033 13.3 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG23871.1 - 0.017 15.7 0.1 1.6 9.4 0.0 2.4 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 OAG23871.1 - 0.019 14.2 0.0 0.099 11.8 0.0 2.1 1 1 2 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.19 OAG23871.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG23871.1 - 0.059 12.8 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG23871.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OAG23871.1 - 0.078 13.4 0.1 0.21 12.1 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 OAG23872.1 - 1.3e-26 93.3 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain DUF1100 PF06500.11 OAG23873.1 - 0.17 10.7 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) adh_short PF00106.25 OAG23875.1 - 4.7e-34 117.6 0.0 2.5e-25 89.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG23875.1 - 1e-20 74.3 0.0 1.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG23875.1 - 9.8e-10 38.6 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG23875.1 - 0.00072 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG23875.1 - 0.063 12.7 0.0 0.41 10.1 0.0 2.2 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG23875.1 - 0.068 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF4472 PF14739.6 OAG23875.1 - 0.1 13.4 0.2 0.15 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) HILPDA PF15220.6 OAG23875.1 - 0.18 12.0 0.7 0.6 10.3 0.2 2.0 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated Piezo_RRas_bdg PF12166.8 OAG23876.1 - 0.0058 16.0 0.1 0.0077 15.6 0.1 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain DUF5504 PF17608.2 OAG23876.1 - 0.012 15.7 1.1 0.022 14.9 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DUF5336 PF17270.2 OAG23876.1 - 0.033 13.8 2.9 0.048 13.3 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Peptidase_C14 PF00656.22 OAG23878.1 - 0.0004 20.4 0.0 0.00087 19.3 0.0 1.7 1 1 0 1 1 1 1 Caspase domain C_Hendra PF16821.5 OAG23878.1 - 0.053 13.4 1.3 0.14 12.1 1.3 1.6 1 0 0 1 1 1 0 C protein from hendra and measles viruses Raptor_N PF14538.6 OAG23878.1 - 1.3 8.9 5.5 0.66 9.9 1.1 2.6 2 2 1 3 3 3 0 Raptor N-terminal CASPase like domain Peptidase_M28 PF04389.17 OAG23879.1 - 6.7e-31 107.5 0.0 9.5e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG23879.1 - 4.5e-08 33.1 0.1 2.6e-07 30.6 0.1 2.0 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 OAG23880.1 - 1.1e-23 84.1 3.9 1.4e-23 83.8 2.6 1.8 2 1 0 2 2 2 1 R3H-associated N-terminal domain HIT PF01230.23 OAG23882.1 - 9.3e-24 84.0 0.3 1.4e-23 83.4 0.3 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG23882.1 - 0.00013 22.5 0.1 0.00023 21.6 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding EF-hand_7 PF13499.6 OAG23884.1 - 7.3e-12 45.6 1.5 1.3e-06 28.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG23884.1 - 3.5e-11 42.1 1.8 0.0004 20.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OAG23884.1 - 8e-10 37.6 2.3 0.0017 17.8 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAG23884.1 - 1.1e-08 35.2 0.0 0.002 18.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAG23884.1 - 0.00041 20.1 1.9 0.1 12.4 0.2 3.7 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG23884.1 - 0.00096 18.5 3.0 0.25 10.9 0.5 2.9 2 0 0 2 2 2 2 EF hand MFS_1 PF07690.16 OAG23885.1 - 3.2e-37 128.3 23.1 4.5e-28 98.2 8.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG23885.1 - 1.6e-13 50.3 7.2 1.6e-13 50.3 7.2 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG23885.1 - 0.0016 17.0 3.1 0.0028 16.1 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AFG1_ATPase PF03969.16 OAG23886.1 - 2.3e-90 303.1 0.0 7.5e-86 288.3 0.0 2.5 2 1 0 2 2 2 2 AFG1-like ATPase DHHC PF01529.20 OAG23886.1 - 7.3e-36 123.2 6.9 7.3e-36 123.2 6.9 2.6 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAG23886.1 - 1.4e-31 108.9 0.0 8.2e-11 42.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG23886.1 - 2.6e-22 78.6 0.7 4.4e-07 30.1 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG23886.1 - 6.8e-22 77.6 2.2 1.6e-06 28.5 0.2 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG23886.1 - 1.5e-20 72.6 1.9 0.00021 21.6 0.3 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OAG23886.1 - 1e-16 59.3 2.9 8.4e-06 25.8 0.2 6.2 5 0 0 5 5 5 3 Ankyrin repeat YfhO PF09586.10 OAG23886.1 - 0.0066 14.7 5.4 0.0096 14.2 5.4 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF5337 PF17272.2 OAG23886.1 - 0.47 10.3 3.1 1.5 8.7 3.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5337) ABC_tran PF00005.27 OAG23887.1 - 2.9e-47 160.6 0.0 8.5e-29 100.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG23887.1 - 1.9e-42 145.8 24.9 2.4e-25 89.7 11.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 OAG23887.1 - 1.2e-13 51.0 1.0 4.2e-07 29.6 0.0 4.2 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG23887.1 - 7.7e-08 32.7 0.1 0.0073 16.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG23887.1 - 1.9e-07 31.2 0.7 0.14 12.0 0.0 4.4 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG23887.1 - 9.3e-06 26.1 2.6 0.085 13.2 0.1 3.5 3 1 1 4 4 2 2 AAA ATPase domain AAA_29 PF13555.6 OAG23887.1 - 1.5e-05 24.6 0.3 0.01 15.5 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG23887.1 - 1.9e-05 25.2 2.4 0.0051 17.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAG23887.1 - 3.4e-05 23.5 0.1 0.00048 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAG23887.1 - 0.00036 20.7 0.7 0.00082 19.5 0.7 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 OAG23887.1 - 0.00079 19.4 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 OAG23887.1 - 0.0025 16.9 0.2 0.11 11.6 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 OAG23887.1 - 0.0034 17.4 0.1 1.4 9.0 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAG23887.1 - 0.0035 16.7 0.1 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 OAG23887.1 - 0.0061 16.5 0.2 1.7 8.5 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 OAG23887.1 - 0.02 15.0 0.0 9 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG23887.1 - 0.038 14.4 0.0 5.2 7.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 OAG23887.1 - 0.071 13.2 0.1 38 4.3 0.0 3.1 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 OAG23887.1 - 0.079 12.5 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OAG23887.1 - 0.09 12.8 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OAG23887.1 - 0.091 12.3 2.4 7.5 6.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG23887.1 - 0.1 12.5 0.0 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OAG23887.1 - 0.13 12.0 0.2 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 OAG23887.1 - 0.15 10.8 1.8 0.45 9.2 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T5orf172 PF10544.9 OAG23888.1 - 3.7e-16 59.5 1.9 5.8e-16 58.9 1.0 1.8 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 OAG23888.1 - 6.1e-11 42.8 1.7 1.5e-10 41.6 1.7 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Arteri_Gl PF00951.18 OAG23888.1 - 0.65 9.8 3.6 1.1 9.1 3.6 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Cutinase PF01083.22 OAG23889.1 - 5.5e-50 169.8 0.1 8e-50 169.3 0.1 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG23889.1 - 0.00084 19.0 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG23889.1 - 0.0017 18.3 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) EF-hand_5 PF13202.6 OAG23890.1 - 0.36 10.4 1.1 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 EF hand Amidase PF01425.21 OAG23891.1 - 1.2e-31 110.2 0.3 2.4e-31 109.2 0.1 1.4 2 0 0 2 2 2 1 Amidase Pectinesterase PF01095.19 OAG23893.1 - 1.4e-52 178.3 8.1 1.9e-52 177.9 8.1 1.1 1 0 0 1 1 1 1 Pectinesterase EamA PF00892.20 OAG23894.1 - 8.8e-26 90.7 34.8 5e-14 52.6 11.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAG23894.1 - 9.4 5.3 14.3 0.51 9.5 5.7 2.7 3 1 0 3 3 3 0 UAA transporter family Adhesin_P1 PF03257.13 OAG23895.1 - 0.032 14.8 0.1 0.055 14.0 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma adhesin P1 DUF5527 PF17665.1 OAG23895.1 - 0.39 10.3 2.0 0.75 9.3 1.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5527) Dehydratase_hem PF13816.6 OAG23896.1 - 1.9e-109 365.8 0.1 2.1e-109 365.7 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 OAG23896.1 - 6.5e-08 32.9 0.1 0.0049 17.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Glyco_transf_90 PF05686.12 OAG23898.1 - 5.9e-15 55.1 2.4 5.8e-14 51.8 1.9 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG23898.1 - 0.037 14.4 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fe-ADH PF00465.19 OAG23899.1 - 2.9e-64 217.2 0.1 3.7e-64 216.8 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG23899.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase HSP70 PF00012.20 OAG23900.1 - 2.9e-266 884.4 17.6 3.4e-266 884.2 17.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG23900.1 - 3e-14 52.6 4.4 6e-13 48.3 1.6 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 OAG23900.1 - 0.00073 19.3 0.1 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SMBP PF16785.5 OAG23900.1 - 0.15 12.3 8.7 0.088 13.0 6.3 2.0 2 0 0 2 2 2 0 Small metal-binding protein DUF4363 PF14276.6 OAG23900.1 - 0.56 10.3 8.1 1.1 9.4 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF2415 PF10313.9 OAG23901.1 - 1.3e-17 63.4 0.0 3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HypD PF01924.16 OAG23901.1 - 0.22 10.5 0.1 0.58 9.2 0.0 1.6 2 0 0 2 2 2 0 Hydrogenase formation hypA family PQQ_3 PF13570.6 OAG23901.1 - 0.4 11.2 3.2 29 5.3 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain Cys_Met_Meta_PP PF01053.20 OAG23902.1 - 1.8e-137 458.0 0.0 2.1e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG23902.1 - 3.6e-06 26.4 0.0 5.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG23902.1 - 3.3e-05 23.3 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG23902.1 - 4.9e-05 22.4 0.0 8.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG23902.1 - 0.037 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase TQ PF18202.1 OAG23902.1 - 0.14 12.7 0.1 0.4 11.2 0.1 1.7 2 0 0 2 2 2 0 T-Q ester bond containing domain FaeA PF04703.12 OAG23903.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein Bestrophin PF01062.21 OAG23904.1 - 3.8e-35 121.7 0.1 6.1e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FOXO-TAD PF16676.5 OAG23904.1 - 0.17 12.4 0.8 19 5.8 0.1 2.5 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family U-box PF04564.15 OAG23907.1 - 2.3e-21 75.7 0.0 4.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 OAG23907.1 - 8.5e-11 41.2 3.5 1.5e-05 24.6 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG23907.1 - 9.9e-09 34.8 1.0 1.5e-07 30.9 0.6 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 OAG23907.1 - 3.8e-08 32.8 1.7 0.00014 21.7 0.5 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG23907.1 - 1.8e-06 28.4 2.6 0.00089 19.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG23907.1 - 3e-05 24.1 3.2 0.72 10.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23907.1 - 0.00073 20.2 1.6 0.4 11.6 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 OAG23907.1 - 0.00086 20.0 9.7 0.0017 19.0 9.7 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_12 PF13424.6 OAG23907.1 - 0.0019 18.4 1.9 0.32 11.3 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG23907.1 - 0.0025 18.0 1.8 0.036 14.3 0.5 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAG23907.1 - 0.0031 17.4 0.3 0.77 9.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 OAG23907.1 - 0.0054 16.8 0.0 0.041 14.0 0.0 2.4 3 0 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_16 PF13432.6 OAG23907.1 - 0.0062 17.2 0.2 0.024 15.3 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23907.1 - 0.1 12.8 0.6 0.72 10.2 0.2 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAG23907.1 - 0.26 11.7 5.7 6.7 7.1 0.1 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG23907.1 - 0.28 11.9 2.2 13 6.7 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR_long PF17177.4 OAG23907.1 - 0.43 9.9 6.2 3.6 6.9 0.1 2.4 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP AMP-binding PF00501.28 OAG23909.1 - 4.8e-24 84.7 0.0 6.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG23909.1 - 0.014 16.3 0.3 0.032 15.2 0.3 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_28 PF00295.17 OAG23910.1 - 4.1e-48 164.1 13.3 5.2e-48 163.8 13.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 OAG23910.1 - 0.0015 18.4 4.7 0.0015 18.4 4.7 2.4 1 1 1 2 2 2 1 Right handed beta helix region DHO_dh PF01180.21 OAG23911.1 - 2.1e-64 217.6 0.1 1e-52 179.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 OAG23911.1 - 0.0099 15.3 0.4 0.03 13.7 0.1 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase PcrB PF01884.17 OAG23911.1 - 0.3 10.5 2.9 1.5 8.2 0.1 2.6 3 0 0 3 3 3 0 PcrB family MFS_1 PF07690.16 OAG23912.1 - 5e-45 153.9 48.6 5e-45 153.9 48.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG23912.1 - 1.5e-13 50.1 24.8 5.2e-13 48.3 24.8 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 OAG23912.1 - 0.019 15.2 7.4 0.047 14.0 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DUF829 PF05705.14 OAG23913.1 - 5e-47 160.8 0.1 9.8e-47 159.9 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) Cutinase PF01083.22 OAG23914.1 - 5.3e-50 169.8 0.3 6.2e-50 169.6 0.3 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 OAG23914.1 - 0.0006 19.7 0.0 0.0014 18.6 0.0 1.4 1 1 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 OAG23914.1 - 0.00063 19.4 0.1 0.00082 19.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Trehalase PF01204.18 OAG23915.1 - 7.7e-114 381.3 7.9 3.3e-113 379.2 7.9 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 OAG23915.1 - 0.00034 19.7 0.1 0.00056 18.9 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase TPR_12 PF13424.6 OAG23915.1 - 0.14 12.5 0.2 0.54 10.6 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3176 PF11374.8 OAG23918.1 - 1.8e-29 102.1 2.9 7e-29 100.2 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) ZZ PF00569.17 OAG23920.1 - 5.2e-11 42.2 4.3 1e-10 41.3 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 OAG23920.1 - 1.1e-09 38.5 0.0 4.9e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 OAG23920.1 - 2.8e-08 33.8 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0167 PF03691.14 OAG23920.1 - 0.055 13.3 0.9 0.15 11.8 0.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Pkinase PF00069.25 OAG23921.1 - 1.6e-69 234.2 0.0 2e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG23921.1 - 2.1e-34 119.0 0.0 2.9e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG23921.1 - 6.1e-11 42.8 0.3 1.6e-10 41.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAG23921.1 - 1.3e-06 27.6 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG23921.1 - 0.0036 16.7 0.0 0.0061 15.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like C2 PF00168.30 OAG23921.1 - 0.014 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 C2 domain FTA2 PF13095.6 OAG23921.1 - 0.15 11.7 0.1 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGI PF00342.19 OAG23922.1 - 2.8e-242 804.5 2.9 3.2e-242 804.4 2.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 OAG23924.1 - 1.8e-10 40.4 1.7 2.9e-10 39.7 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 OAG23925.1 - 1.9e-13 50.5 2.3 2.2e-13 50.3 0.5 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 OAG23925.1 - 0.024 14.5 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2795 PF11387.8 OAG23925.1 - 0.029 14.6 0.1 0.13 12.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) MR_MLE_C PF13378.6 OAG23926.1 - 1e-55 188.7 0.0 1.7e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG23926.1 - 0.00024 20.3 0.0 0.00046 19.4 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 OAG23926.1 - 0.00066 19.9 0.2 0.0024 18.1 0.0 1.9 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 OAG23927.1 - 2.4e-38 131.5 0.0 3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rsa3 PF14615.6 OAG23928.1 - 3.4e-20 71.3 0.1 4.7e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.9 OAG23928.1 - 0.0038 16.9 18.0 0.0047 16.6 18.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SWIRM-assoc_2 PF16496.5 OAG23928.1 - 0.007 15.3 15.9 0.0082 15.1 15.9 1.0 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal DUF243 PF03103.17 OAG23928.1 - 0.019 15.3 3.3 0.019 15.3 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Zip PF02535.22 OAG23928.1 - 0.29 10.3 3.4 0.37 10.0 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rubella_Capsid PF05750.11 OAG23928.1 - 0.44 10.1 7.5 0.55 9.8 7.5 1.1 1 0 0 1 1 1 0 Rubella capsid protein NPR3 PF03666.13 OAG23928.1 - 0.86 8.3 8.9 0.92 8.2 8.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OAG23928.1 - 0.98 7.7 9.0 1 7.7 9.0 1.2 1 0 0 1 1 1 0 Menin DUF3275 PF11679.8 OAG23928.1 - 1.3 8.9 7.5 1.5 8.7 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) SOBP PF15279.6 OAG23928.1 - 2.4 8.7 11.5 2.8 8.5 11.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SPATA3 PF15662.5 OAG23928.1 - 2.7 8.6 19.2 3.7 8.1 19.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Dsh_C PF12316.8 OAG23928.1 - 2.8 8.3 13.1 3.8 7.9 13.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 OAG23928.1 - 6 6.6 12.1 8.2 6.2 12.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 OAG23928.1 - 6.4 5.5 9.8 7.1 5.3 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 OAG23928.1 - 9.6 4.9 10.2 9.8 4.8 10.2 1.2 1 0 0 1 1 1 0 Presenilin TPR_22 PF18833.1 OAG23929.1 - 2e-07 31.1 0.0 5.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG23929.1 - 3.2e-07 30.9 14.1 6e-07 30.0 8.2 2.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23929.1 - 3.7e-05 23.6 6.6 0.0079 16.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23929.1 - 8.5e-05 23.1 11.9 0.0057 17.4 0.6 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG23929.1 - 0.0032 17.1 0.2 0.0032 17.1 0.2 2.5 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OAG23929.1 - 0.011 16.2 12.3 2.4 8.7 0.2 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23929.1 - 0.014 15.7 6.6 0.76 10.1 1.8 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Prok-E2_C PF14459.6 OAG23929.1 - 0.028 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C TPR_1 PF00515.28 OAG23929.1 - 0.085 12.7 0.5 0.085 12.7 0.5 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG23929.1 - 0.093 12.9 11.2 1.9 8.8 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG23930.1 - 5.9e-35 117.7 13.6 8.4e-05 22.2 0.0 13.8 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 OAG23930.1 - 6e-31 104.0 24.8 0.0035 17.3 0.0 14.3 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23930.1 - 1.4e-26 90.4 17.9 0.019 15.1 0.0 13.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAG23930.1 - 2.1e-24 84.1 5.6 0.0034 17.7 0.6 11.2 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23930.1 - 5.2e-22 76.6 15.5 0.24 12.3 0.0 12.8 9 4 4 13 13 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG23930.1 - 3.8e-21 75.2 27.3 0.00045 20.4 0.3 10.4 8 3 1 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG23930.1 - 1.3e-18 67.3 21.2 0.00013 22.4 1.5 12.0 11 2 2 13 13 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG23930.1 - 2.7e-17 62.2 11.9 0.0038 16.9 0.0 10.8 11 0 0 11 11 11 4 TPR repeat TPR_16 PF13432.6 OAG23930.1 - 3e-14 53.4 31.0 0.031 14.9 0.1 11.5 10 2 2 12 12 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG23930.1 - 2.2e-10 39.8 17.6 8.3 6.7 0.4 11.9 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG23930.1 - 2.2e-09 37.3 3.6 0.38 10.9 0.0 8.0 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG23930.1 - 9.7e-06 25.9 26.7 4.8 8.0 0.0 12.2 13 0 0 13 13 11 1 Tetratricopeptide repeat ChAPs PF09295.10 OAG23930.1 - 0.0013 17.9 1.0 10 5.0 0.0 4.9 4 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 OAG23930.1 - 0.0082 16.5 6.9 20 5.6 0.1 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OAG23930.1 - 0.13 12.0 5.7 36 4.0 0.0 5.0 6 0 0 6 6 5 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 OAG23930.1 - 0.22 11.4 18.4 11 6.0 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat HemY_N PF07219.13 OAG23930.1 - 0.68 10.2 7.8 25 5.1 0.0 4.9 5 1 1 6 6 4 0 HemY protein N-terminus Sel1 PF08238.12 OAG23930.1 - 1.9 9.3 5.5 32 5.4 0.1 4.1 4 0 0 4 4 3 0 Sel1 repeat BTB PF00651.31 OAG23931.1 - 2.6e-05 24.4 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CLP_protease PF00574.23 OAG23932.1 - 1.4e-77 259.7 0.0 1.8e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.6 OAG23932.1 - 0.033 14.4 0.3 0.033 14.4 0.3 1.7 2 0 0 2 2 2 0 Clr5 domain RRG8 PF17068.5 OAG23933.1 - 0.041 13.3 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Required for respiratory growth protein 8 mitochondrial Acetyltransf_3 PF13302.7 OAG23934.1 - 9.3e-27 94.4 0.0 1.1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG23934.1 - 9.6e-07 29.1 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG23934.1 - 9.8e-06 25.8 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OAG23935.1 - 3.8e-28 97.3 0.1 1.4e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAG23935.1 - 3.1e-14 52.5 1.3 6.6e-14 51.5 1.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 OAG23935.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG23935.1 - 0.19 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PHTB1_N PF14727.6 OAG23939.1 - 0.02 14.3 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 PTHB1 N-terminus YtxH PF12732.7 OAG23941.1 - 0.0086 16.6 3.1 0.0086 16.6 3.1 2.0 1 1 1 2 2 2 2 YtxH-like protein CsbD PF05532.12 OAG23941.1 - 0.014 15.3 22.6 0.061 13.2 13.5 3.1 2 1 1 3 3 3 0 CsbD-like LEA_4 PF02987.16 OAG23941.1 - 0.017 15.2 6.5 0.017 15.2 6.5 2.6 2 1 1 3 3 3 0 Late embryogenesis abundant protein DUF883 PF05957.13 OAG23941.1 - 0.087 13.4 3.3 0.12 13.0 1.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) REF PF05755.12 OAG23941.1 - 0.096 12.5 0.4 0.14 11.9 0.4 1.4 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) COesterase PF00135.28 OAG23942.1 - 4.4e-76 256.8 0.0 6.2e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG23942.1 - 1e-06 28.8 0.2 7.1e-06 26.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF695 PF05117.12 OAG23942.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF695) Cupin_2 PF07883.11 OAG23944.1 - 3.1e-15 55.6 0.5 5.5e-15 54.8 0.5 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG23944.1 - 1.9e-07 31.0 0.4 3.6e-07 30.2 0.4 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 OAG23944.1 - 2.5e-05 24.2 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 OAG23944.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG23944.1 - 0.00072 19.2 0.5 0.018 14.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG23944.1 - 0.0021 18.2 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Auxin_BP PF02041.16 OAG23944.1 - 0.0052 16.5 0.1 0.017 14.8 0.1 1.7 1 1 0 1 1 1 1 Auxin binding protein GPI PF06560.11 OAG23944.1 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Ectoine_synth PF06339.12 OAG23944.1 - 0.038 14.2 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Ectoine synthase Cupin_6 PF12852.7 OAG23944.1 - 0.059 13.1 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin DMSP_lyase PF16867.5 OAG23944.1 - 0.059 13.0 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_7 PF12973.7 OAG23944.1 - 0.12 12.3 0.1 0.57 10.1 0.1 1.9 2 0 0 2 2 2 0 ChrR Cupin-like domain F-box PF00646.33 OAG23945.1 - 0.16 11.9 2.4 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 F-box domain Folliculin PF11704.8 OAG23947.1 - 1.1e-54 185.1 0.0 1.7e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport MT0933_antitox PF14013.6 OAG23948.1 - 0.054 13.8 4.8 0.088 13.1 1.3 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein MT0933_antitox PF14013.6 OAG23949.1 - 0.057 13.7 2.7 2.1 8.7 0.7 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein RINT1_TIP1 PF04437.13 OAG23950.1 - 9.5e-175 582.2 0.0 3.7e-174 580.3 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 OAG23950.1 - 0.4 11.2 7.1 0.14 12.7 3.4 2.2 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PUF PF00806.19 OAG23951.1 - 7.3e-12 44.3 0.0 0.64 9.8 0.1 7.8 8 0 0 8 8 8 3 Pumilio-family RNA binding repeat TetR_C_16 PF17920.1 OAG23951.1 - 0.14 12.4 0.3 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ParD PF09386.10 OAG23951.1 - 0.19 12.1 1.6 13 6.3 0.0 3.0 2 0 0 2 2 2 0 Antitoxin ParD Pyridoxal_deC PF00282.19 OAG23952.1 - 8.7e-77 258.4 0.0 1.6e-76 257.5 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAG23952.1 - 8.9e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG23952.1 - 0.00087 18.3 0.0 0.0023 17.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_17 PF00332.18 OAG23953.1 - 2.9e-05 23.8 1.0 7.1e-05 22.5 0.3 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 HrpF PF06266.12 OAG23953.1 - 0.11 12.8 0.1 3.9 7.8 0.1 2.6 2 0 0 2 2 2 0 HrpF protein MBOAT PF03062.19 OAG23954.1 - 3.8e-45 154.8 18.6 7.7e-45 153.7 18.6 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.19 OAG23955.1 - 6.9e-137 456.4 0.0 7.7e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Actin Proteasome PF00227.26 OAG23956.1 - 9.3e-48 162.2 0.1 1.2e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 OAG23956.1 - 9.1e-14 50.6 1.3 9.1e-14 50.6 1.3 2.0 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Arc_PepC PF06819.11 OAG23956.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain WD40 PF00400.32 OAG23957.1 - 0.0014 19.4 0.8 0.33 11.9 0.2 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat SDA1 PF05285.12 OAG23957.1 - 0.2 11.1 11.7 0.38 10.1 11.7 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAG23957.1 - 0.36 9.0 14.6 0.64 8.2 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 OAG23957.1 - 0.64 10.1 10.1 2 8.5 10.1 1.8 1 0 0 1 1 1 0 YL1 nuclear protein DnaJ PF00226.31 OAG23958.1 - 5.2e-19 68.1 2.0 2.4e-18 66.0 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C3HC4_3 PF13920.6 OAG23958.1 - 3.7 7.5 11.0 45 4.0 11.0 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABM PF03992.16 OAG23959.1 - 8.7e-09 35.4 0.1 5.3e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 OAG23959.1 - 0.027 14.8 0.0 1.9 8.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1330) Tma16 PF11176.8 OAG23960.1 - 8.6e-48 161.9 2.3 1.2e-47 161.5 2.3 1.2 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Rab_eff_C PF04698.12 OAG23960.1 - 0.0084 14.5 0.3 0.01 14.2 0.3 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus XPG_N PF00752.17 OAG23961.1 - 2.1e-23 82.7 0.0 4.1e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAG23961.1 - 2.3e-22 79.2 0.0 5.4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAG23961.1 - 7.3e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAG23961.1 - 0.00082 19.9 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAG23961.1 - 0.2 12.3 0.2 28 5.4 0.1 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain DNase_NucA_NucB PF14040.6 OAG23962.1 - 1.7e-08 34.8 2.4 3.5e-08 33.8 2.4 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Toxin_2 PF00451.19 OAG23962.1 - 0.089 13.1 0.3 0.089 13.1 0.3 2.8 4 0 0 4 4 4 0 Scorpion short toxin, BmKK2 Ank_3 PF13606.6 OAG23964.1 - 1.2e-05 25.3 0.0 0.41 11.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OAG23964.1 - 0.0003 21.3 0.0 0.00092 19.8 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23964.1 - 0.0095 16.5 0.0 0.044 14.4 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Bromodomain PF00439.25 OAG23965.1 - 6.7e-42 141.5 8.9 6e-21 74.3 0.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 OAG23965.1 - 2e-17 63.2 0.7 5.1e-17 61.9 0.7 1.7 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 OAG23965.1 - 0.23 9.7 19.8 0.031 12.6 11.0 2.2 2 0 0 2 2 2 0 CDC45-like protein OTU PF02338.19 OAG23966.1 - 5.6e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-BED PF02892.15 OAG23966.1 - 0.16 12.0 1.1 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 BED zinc finger UN_NPL4 PF11543.8 OAG23966.1 - 0.16 12.4 0.0 1.8 9.1 0.0 2.4 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Cellulase PF00150.18 OAG23967.1 - 1.2e-09 38.0 0.5 2.6e-09 36.9 0.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BTB PF00651.31 OAG23968.1 - 4.1e-06 27.0 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG23969.1 - 0.00019 21.6 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DnaJ PF00226.31 OAG23970.1 - 2.1e-22 79.0 2.2 6.6e-22 77.4 2.2 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 OAG23970.1 - 1.7e-18 65.1 3.1 0.00013 21.8 0.1 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG23970.1 - 2.2e-16 58.9 5.0 7.5e-06 25.5 0.0 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG23970.1 - 9.7e-10 37.9 1.6 0.0057 16.8 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG23970.1 - 3e-08 33.7 6.5 0.0011 19.1 0.4 5.3 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG23970.1 - 2.2e-07 30.8 0.6 0.0014 18.9 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG23970.1 - 4.1e-07 30.3 5.9 1.3 10.0 0.1 6.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG23970.1 - 4.6e-07 30.2 7.5 0.0039 17.7 0.3 5.0 4 3 1 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG23970.1 - 5e-05 23.9 8.3 0.0028 18.3 0.6 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG23970.1 - 7.8e-05 23.1 9.0 5.3 7.9 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG23970.1 - 0.0036 17.2 1.9 8.4 6.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG23970.1 - 0.0082 16.4 7.4 5.2 7.4 0.1 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 OAG23970.1 - 0.0093 14.7 0.3 0.021 13.6 0.3 1.6 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 OAG23970.1 - 0.033 14.5 11.7 0.099 12.9 0.5 5.4 4 3 1 5 5 5 0 Tetratricopeptide repeat GRP PF07172.11 OAG23970.1 - 0.26 12.0 7.3 0.54 11.0 7.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family Fis1_TPR_C PF14853.6 OAG23970.1 - 0.5 10.5 2.2 13 5.9 0.0 3.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 OAG23970.1 - 1.1 9.0 7.8 0.3 10.8 0.2 3.9 5 0 0 5 5 5 0 TPR repeat POTRA PF07244.15 OAG23970.1 - 2 9.0 4.5 80 3.9 0.0 3.8 3 1 1 4 4 4 0 Surface antigen variable number repeat Glyco_hydro_5_C PF18564.1 OAG23971.1 - 2.7e-21 75.9 0.0 1.1e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAG23971.1 - 7.1e-11 42.1 4.7 1.8e-08 34.2 2.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.12 OAG23972.1 - 3.3e-11 43.4 1.8 3.7e-09 36.8 1.8 3.4 1 1 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 OAG23972.1 - 1.4e-05 24.9 0.0 0.0014 18.5 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain IFRD PF05004.13 OAG23972.1 - 3.8e-05 22.9 1.6 0.0012 18.1 0.1 3.0 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) MOR2-PAG1_N PF14222.6 OAG23972.1 - 0.0017 17.4 0.0 0.0042 16.1 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal RIX1 PF08167.12 OAG23972.1 - 0.092 12.5 0.2 0.83 9.4 0.0 2.8 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF5578 PF17741.1 OAG23972.1 - 0.13 11.7 1.0 5.8 6.2 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5578) DIOX_N PF14226.6 OAG23973.1 - 1.3e-28 100.1 0.0 2.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG23973.1 - 2.6e-14 53.5 0.0 4.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.12 OAG23974.1 - 1.9e-176 588.2 0.0 2.3e-176 587.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CUE PF02845.16 OAG23975.1 - 3.5e-11 42.6 0.1 7.6e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 OAG23976.1 - 2.9e-28 98.0 0.6 3.4e-28 97.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e COG5 PF10392.9 OAG23978.1 - 0.022 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 D-ser_dehydrat PF14031.6 OAG23979.1 - 2.1e-23 82.8 0.0 4.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 OAG23979.1 - 5e-13 49.2 0.0 7.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PKD_channel PF08016.12 OAG23980.1 - 0.53 8.9 3.9 0.53 8.9 0.9 2.1 2 0 0 2 2 2 0 Polycystin cation channel DnaJ PF00226.31 OAG23981.1 - 6.3e-15 55.0 0.1 1.2e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain MFS_5 PF05631.14 OAG23982.1 - 8.4e-59 199.3 1.7 1.2e-58 198.7 1.7 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OAG23982.1 - 1.2e-22 80.3 20.5 1.7e-22 79.8 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG23982.1 - 0.00012 21.1 4.1 0.0072 15.2 0.0 2.2 1 1 1 2 2 2 2 MFS_1 like family Methyltransf_22 PF13383.6 OAG23983.1 - 3.7e-13 49.6 0.0 5.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OAG23983.1 - 4.5e-09 36.6 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain 2_5_RNA_ligase2 PF13563.6 OAG23984.1 - 2e-27 96.0 0.0 4.8e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 OAG23984.1 - 6.9e-21 74.4 0.1 1.7e-20 73.1 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain MJ1316 PF04457.12 OAG23984.1 - 3.3e-19 69.4 0.0 9.8e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 OAG23984.1 - 3.4e-08 33.3 0.1 1.1e-07 31.7 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 OAG23984.1 - 4.7e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 OAG23984.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DUF4460 PF14687.6 OAG23985.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) MARVEL PF01284.23 OAG23986.1 - 0.00047 20.2 2.4 0.001 19.1 2.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 OAG23986.1 - 0.0013 19.2 0.4 0.028 14.9 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4231) MscL PF01741.18 OAG23986.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.8 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL TRAF_BIRC3_bd PF16673.5 OAG23986.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Transferase PF02458.15 OAG23987.1 - 0.00075 18.3 0.0 0.0013 17.4 0.0 1.3 1 0 0 1 1 1 1 Transferase family DUF443 PF04276.12 OAG23988.1 - 0.043 13.6 1.9 0.061 13.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Cortexin PF11057.8 OAG23988.1 - 0.34 10.8 0.1 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Cortexin of kidney Acyl_transf_3 PF01757.22 OAG23988.1 - 1.3 8.0 5.8 2.9 6.8 5.8 1.5 1 1 0 1 1 1 0 Acyltransferase family Peptidase_C14 PF00656.22 OAG23990.1 - 0.00011 22.2 0.1 0.001 19.1 0.1 2.1 1 1 0 1 1 1 1 Caspase domain Sugar_tr PF00083.24 OAG23991.1 - 7.3e-85 285.5 23.4 8.7e-85 285.3 23.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG23991.1 - 5.9e-17 61.6 28.8 5.9e-17 61.6 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG23992.1 - 1.5e-12 47.1 0.0 2.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG23992.1 - 0.0083 16.2 5.6 0.015 15.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase_2 PF16499.5 OAG23993.1 - 6.3e-57 192.9 3.5 7.7e-55 186.1 3.5 2.3 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG23993.1 - 1.9e-10 40.6 0.0 3.1e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG23993.1 - 3.1e-07 29.7 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase Abhydrolase_1 PF00561.20 OAG23994.1 - 2.3e-16 60.3 0.3 4.1e-16 59.4 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG23994.1 - 2.1e-12 48.1 0.9 2.9e-12 47.6 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG23994.1 - 6.4e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 OAG23994.1 - 0.017 15.5 0.6 0.036 14.4 0.3 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ndr PF03096.14 OAG23994.1 - 0.018 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family HTH_Tnp_Tc5 PF03221.16 OAG23995.1 - 0.00077 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAG23995.1 - 0.58 11.1 27.4 0.44 11.5 7.0 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OAG23995.1 - 0.75 10.5 4.6 0.8 10.4 0.4 2.7 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats TruB_N PF01509.18 OAG23996.1 - 1.1e-41 142.7 0.0 3.6e-41 141.0 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG23996.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Ank_2 PF12796.7 OAG23997.1 - 2.4e-09 37.7 0.3 0.0035 17.9 0.0 4.0 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG23997.1 - 0.00073 20.1 1.4 9.9 6.9 0.1 4.6 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG23997.1 - 0.0059 17.0 5.0 1.6e+02 3.4 0.0 6.9 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 OAG23997.1 - 0.24 11.8 8.3 8.6 6.8 0.1 5.5 6 0 0 6 6 6 0 Ankyrin repeats (many copies) zf-AN1 PF01428.16 OAG24000.1 - 6.8e-23 80.6 26.3 2.6e-11 43.5 10.0 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 OAG24000.1 - 0.003 17.7 18.9 0.02 15.1 5.1 2.6 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 OAG24000.1 - 0.013 15.9 16.6 0.04 14.3 2.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C5HC2 PF02928.16 OAG24000.1 - 0.048 14.0 13.4 0.25 11.8 0.5 2.7 3 0 0 3 3 3 0 C5HC2 zinc finger Ank_4 PF13637.6 OAG24001.1 - 1.9e-11 44.3 0.2 0.29 11.7 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG24001.1 - 1.7e-07 31.7 0.0 3.6e-05 24.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG24001.1 - 3.6e-06 26.9 0.2 4.7 8.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OAG24001.1 - 4.7e-06 26.8 1.7 0.077 13.3 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG24001.1 - 9.5e-05 22.7 0.5 0.77 10.3 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Helo_like_N PF17111.5 OAG24001.1 - 0.00022 20.7 1.6 0.00047 19.6 1.3 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PspA_IM30 PF04012.12 OAG24001.1 - 0.3 10.6 3.3 0.52 9.8 3.3 1.3 1 0 0 1 1 1 0 PspA/IM30 family HATPase_c PF02518.26 OAG24002.1 - 1.4e-23 83.5 0.0 4e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG24002.1 - 1e-18 67.6 2.1 1.6e-11 44.4 0.2 3.5 3 1 0 3 3 3 2 Response regulator receiver domain PAS_3 PF08447.12 OAG24002.1 - 3.6e-16 59.2 0.4 4.1e-07 30.2 0.1 3.3 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 OAG24002.1 - 3e-14 53.1 0.0 1.3e-05 25.4 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OAG24002.1 - 6.6e-11 42.2 0.0 2.5e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAG24002.1 - 1.1e-10 41.8 0.0 2.5e-05 24.5 0.0 3.5 4 0 0 4 4 4 2 PAS fold HisKA PF00512.25 OAG24002.1 - 3.6e-07 30.1 0.1 1.7e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 OAG24002.1 - 2.3e-06 27.5 0.1 0.25 11.4 0.0 3.9 4 0 0 4 4 4 2 PAS domain dCache_1 PF02743.18 OAG24002.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Cache domain Helicase_C PF00271.31 OAG24003.1 - 4.7e-18 65.5 0.0 2.7e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 OAG24003.1 - 3.7e-11 43.1 0.0 3.6e-05 23.6 0.0 2.8 2 1 1 3 3 3 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OAG24003.1 - 7.3e-08 33.0 0.4 1.6e-07 32.0 0.4 1.5 1 0 0 1 1 1 1 RecQ zinc-binding HTH_Crp_2 PF13545.6 OAG24003.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MTP18 PF10558.9 OAG24004.1 - 1.1e-80 269.6 0.0 1.5e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 OAG24005.1 - 2.5e-14 53.4 0.2 2.7e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Csm1 PF12539.8 OAG24006.1 - 4e-30 104.3 0.2 7.2e-30 103.5 0.2 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 YabA PF06156.13 OAG24006.1 - 0.00021 21.9 3.5 0.0041 17.7 0.7 2.9 1 1 1 2 2 2 1 Initiation control protein YabA APG6_N PF17675.1 OAG24006.1 - 0.002 18.6 9.8 0.002 18.6 9.8 2.5 2 1 0 2 2 1 1 Apg6 coiled-coil region GAS PF13851.6 OAG24006.1 - 0.0029 17.0 11.6 0.026 13.9 3.1 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Filament PF00038.21 OAG24006.1 - 0.0037 16.9 7.1 0.0082 15.8 7.1 1.5 1 0 0 1 1 1 1 Intermediate filament protein NPV_P10 PF05531.12 OAG24006.1 - 0.011 16.2 3.9 0.44 11.0 1.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF480 PF04337.12 OAG24006.1 - 0.025 14.7 1.7 0.047 13.8 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 DUF5094 PF17015.5 OAG24006.1 - 0.029 14.5 0.0 0.029 14.5 0.0 4.1 3 1 0 3 3 2 0 Domain of unknown function (DUF5094) DUF2205 PF10224.9 OAG24006.1 - 0.092 12.8 4.3 0.25 11.3 2.6 2.4 2 0 0 2 2 2 0 Short coiled-coil protein BLOC1_2 PF10046.9 OAG24006.1 - 0.22 11.9 6.8 1.5 9.1 5.7 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.11 OAG24006.1 - 0.27 11.1 5.6 0.05 13.4 1.4 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.8 OAG24006.1 - 0.27 11.5 7.7 11 6.3 4.2 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 OAG24006.1 - 0.3 11.3 3.8 4.4 7.6 0.3 3.0 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 OAG24006.1 - 0.45 9.8 12.3 2.2 7.6 10.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3573 PF12097.8 OAG24006.1 - 0.83 8.4 3.1 1.2 7.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.15 OAG24006.1 - 0.85 9.4 8.9 0.42 10.4 2.5 3.1 1 1 2 3 3 3 0 Septum formation initiator HAUS-augmin3 PF14932.6 OAG24006.1 - 1.4 8.4 10.7 3.4 7.2 10.7 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SKA2 PF16740.5 OAG24006.1 - 2.2 8.1 9.4 1.3 8.9 0.9 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Fzo_mitofusin PF04799.13 OAG24006.1 - 2.2 7.8 4.9 4.5 6.8 3.2 2.3 2 1 0 2 2 2 0 fzo-like conserved region Matrilin_ccoil PF10393.9 OAG24006.1 - 4.3 7.3 7.3 0.98 9.3 0.1 3.2 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Gly_acyl_tr_N PF06021.11 OAG24006.1 - 5.1 7.2 6.6 0.59 10.2 2.2 1.7 2 0 0 2 2 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Chitin_synth_1 PF01644.17 OAG24007.1 - 3.7e-78 261.1 0.1 5.8e-78 260.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase FAD_binding_3 PF01494.19 OAG24007.1 - 3.1e-58 197.7 0.0 4.6e-44 151.1 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 OAG24007.1 - 5.3e-45 153.4 0.0 1.1e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Chitin_synth_1N PF08407.11 OAG24007.1 - 7.9e-26 89.8 0.1 1.6e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG24007.1 - 1.6e-22 79.9 0.2 1.3e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG24007.1 - 4.2e-06 26.8 0.4 1.4e-05 25.1 0.4 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 CRCB PF02537.15 OAG24007.1 - 0.12 12.6 1.3 0.38 11.1 0.9 2.0 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Glyco_tranf_2_3 PF13641.6 OAG24007.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 adh_short PF00106.25 OAG24008.1 - 3.1e-42 144.3 0.0 3.8e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24008.1 - 2.1e-22 79.8 0.0 2.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24008.1 - 2.7e-09 37.2 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAG24008.1 - 3.5e-06 27.5 0.5 8.4e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAG24008.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG24008.1 - 3.5e-05 23.1 0.0 5.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG24008.1 - 7.3e-05 23.0 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG24008.1 - 0.00055 20.0 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 OAG24008.1 - 0.0039 16.6 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG24008.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 OAG24008.1 - 0.017 15.0 0.6 0.03 14.2 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG24008.1 - 0.031 14.4 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 OAG24008.1 - 0.04 13.0 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG24008.1 - 0.045 12.7 0.2 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAG24008.1 - 0.062 13.6 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 OAG24008.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Esterase_phd PF10503.9 OAG24009.1 - 1.2e-20 74.0 0.4 1.6e-20 73.6 0.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG24009.1 - 0.00011 21.8 0.6 0.00026 20.5 0.5 1.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG24009.1 - 0.0084 15.0 0.1 0.024 13.5 0.1 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG24009.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAG24009.1 - 0.045 13.6 0.1 0.19 11.5 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Oxidored_FMN PF00724.20 OAG24010.1 - 4.2e-97 325.5 0.0 4.9e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.19 OAG24011.1 - 1.5e-15 57.3 5.9 3.8e-14 52.7 5.9 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG24011.1 - 9.4e-05 22.6 2.5 0.00031 20.9 2.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG24011.1 - 0.00029 20.2 1.1 0.00045 19.6 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG24011.1 - 0.0027 17.3 5.8 0.088 12.4 4.8 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG24011.1 - 0.0041 17.6 0.4 0.011 16.3 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG24011.1 - 0.012 15.7 0.1 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 OAG24011.1 - 0.024 13.7 0.0 0.093 11.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 OAG24011.1 - 0.035 14.0 0.2 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG24011.1 - 0.036 13.1 4.6 1.1 8.3 1.0 3.1 4 0 0 4 4 4 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG24011.1 - 0.046 12.8 5.2 0.081 12.0 5.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAG24011.1 - 0.076 12.1 0.6 0.12 11.4 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG24011.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase RHH_3 PF12651.7 OAG24011.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain PRKCSH-like PF12999.7 OAG24012.1 - 6.8e-42 143.2 7.7 1.6e-24 86.6 1.2 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAG24012.1 - 4e-33 114.3 1.3 1.3e-32 112.6 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAG24012.1 - 7.8e-10 39.6 0.7 1.8e-09 38.5 0.1 2.0 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein XhlA PF10779.9 OAG24012.1 - 0.067 13.4 4.4 2.1 8.6 0.3 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Tup_N PF08581.10 OAG24012.1 - 0.085 13.2 3.2 0.77 10.1 0.3 2.6 2 0 0 2 2 2 0 Tup N-terminal APG6_N PF17675.1 OAG24012.1 - 0.11 13.0 12.1 0.25 11.9 1.2 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OAG24012.1 - 0.15 12.1 16.8 0.77 9.8 0.4 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 OAG24012.1 - 0.16 12.2 6.6 15 5.9 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) FAM184 PF15665.5 OAG24012.1 - 0.25 11.1 9.8 0.015 15.1 4.4 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3837 PF12939.7 OAG24012.1 - 0.26 11.7 1.0 0.86 10.0 0.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF3837) Mod_r PF07200.13 OAG24012.1 - 0.31 11.2 8.9 7.7 6.6 3.7 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HIP1_clath_bdg PF16515.5 OAG24012.1 - 0.34 11.6 12.3 2.4 8.8 3.5 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 OAG24012.1 - 0.34 11.1 2.8 4.4 7.5 0.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 OAG24012.1 - 0.35 11.2 2.0 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RecG_N PF17190.4 OAG24012.1 - 0.61 10.9 2.7 0.99 10.2 0.4 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain Herpes_UL6 PF01763.16 OAG24012.1 - 0.93 7.9 2.8 0.96 7.9 0.6 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like KfrA_N PF11740.8 OAG24012.1 - 1.6 9.4 15.8 4.1 8.1 3.3 3.7 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term DUF1664 PF07889.12 OAG24012.1 - 2.6 8.1 9.8 4.2 7.4 0.2 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) GreA_GreB_N PF03449.15 OAG24012.1 - 3 8.1 7.4 4.6 7.5 0.6 3.4 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal Fzo_mitofusin PF04799.13 OAG24012.1 - 4.5 6.8 6.0 5 6.6 0.4 2.8 3 0 0 3 3 3 0 fzo-like conserved region Laminin_II PF06009.12 OAG24012.1 - 6 6.9 7.5 1.5 8.8 2.7 2.2 2 1 1 3 3 2 0 Laminin Domain II DUF4140 PF13600.6 OAG24012.1 - 7.2 7.1 15.5 2.6 8.5 3.7 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CC2-LZ PF16516.5 OAG24012.1 - 8.3 6.9 14.6 11 6.4 0.3 3.4 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_2 PF01920.20 OAG24012.1 - 8.4 6.4 15.2 23 5.0 5.8 3.4 2 1 1 3 3 3 0 Prefoldin subunit HET PF06985.11 OAG24014.1 - 1.1e-38 132.9 1.2 2e-38 132.0 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_transf PF09830.9 OAG24015.1 - 1.5e-14 53.9 0.0 3.1e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase UDPG_MGDP_dh_N PF03721.14 OAG24016.1 - 1.5e-40 138.7 0.0 3.5e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAG24016.1 - 2.5e-28 98.5 0.0 3.2e-26 91.8 0.0 3.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAG24016.1 - 2.3e-25 88.6 0.0 5.1e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 OAG24016.1 - 0.015 15.5 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAG24016.1 - 0.018 15.0 0.2 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OAG24016.1 - 0.067 12.8 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAG24016.1 - 0.094 13.3 0.0 17 6.1 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 OAG24016.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phytase-like PF13449.6 OAG24017.1 - 7e-40 137.8 0.6 1.2e-39 137.0 0.6 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase DUF3328 PF11807.8 OAG24019.1 - 3.2e-24 85.9 0.1 4.2e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.22 OAG24020.1 - 4.9e-63 213.5 0.0 6.4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Brr6_like_C_C PF10104.9 OAG24021.1 - 6.8e-43 145.6 0.9 9.8e-43 145.1 0.9 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF1729 PF08354.10 OAG24023.1 - 1.4e-160 534.0 0.0 2.2e-160 533.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAG24023.1 - 1.9e-87 293.8 0.5 4.1e-86 289.4 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 OAG24023.1 - 3.1e-51 173.0 0.0 7.7e-51 171.7 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 OAG24023.1 - 1.4e-37 128.5 0.4 8.3e-37 126.1 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 OAG24023.1 - 2.5e-36 124.0 0.0 5.2e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 OAG24023.1 - 1e-35 123.6 0.0 2.1e-35 122.6 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 OAG24023.1 - 7.6e-25 87.6 0.0 2.7e-24 85.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 OAG24024.1 - 7e-81 270.7 0.1 7e-81 270.7 0.1 2.2 3 0 0 3 3 3 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAG24024.1 - 1.1e-68 230.6 0.0 2.3e-68 229.6 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAG24024.1 - 4.8e-20 72.2 0.0 9.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 OAG24024.1 - 5.9e-19 68.3 0.0 1.4e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 OAG24024.1 - 1.4e-11 44.5 0.0 3.4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 OAG24024.1 - 1.5e-05 24.6 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24024.1 - 0.017 15.1 0.1 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 KR domain Molydop_binding PF01568.21 OAG24024.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Astacin PF01400.24 OAG24025.1 - 5.3e-14 52.3 1.0 3.3e-11 43.2 0.1 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 OAG24025.1 - 0.0006 20.0 0.4 0.0011 19.2 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 OAG24025.1 - 0.05 12.5 0.3 0.08 11.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 OAG24025.1 - 0.085 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Matrixin CFEM PF05730.11 OAG24027.1 - 3.6e-12 46.2 7.3 5.5e-12 45.6 7.3 1.3 1 0 0 1 1 1 1 CFEM domain GCIP PF13324.6 OAG24028.1 - 2.9e-30 105.7 1.3 2.9e-30 105.7 1.3 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting CNDH2_C PF16858.5 OAG24028.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CorA PF01544.18 OAG24029.1 - 0.8 9.0 10.4 6.2 6.1 10.4 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 OAG24030.1 - 1.3e-17 64.0 0.0 2.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24030.1 - 4.3e-08 32.7 0.0 8.5e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase VWA PF00092.28 OAG24030.1 - 0.018 15.3 0.0 0.45 10.7 0.0 2.9 2 1 0 2 2 2 0 von Willebrand factor type A domain Pkinase_fungal PF17667.1 OAG24030.1 - 0.023 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OAG24030.1 - 0.053 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lactamase_B_4 PF13691.6 OAG24031.1 - 1.1e-23 82.7 0.1 2.3e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 OAG24031.1 - 4.7e-08 32.8 0.1 0.00045 19.8 0.0 2.7 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG24031.1 - 0.014 15.4 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily adh_short_C2 PF13561.6 OAG24032.1 - 2.1e-39 135.5 0.0 1.6e-37 129.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24032.1 - 5.3e-27 94.5 0.0 3.1e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Fibrillarin PF01269.17 OAG24033.1 - 5.5e-104 346.2 0.0 6.7e-104 345.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAG24033.1 - 0.00011 22.0 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAG24033.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAG24033.1 - 0.062 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L22 PF00237.19 OAG24034.1 - 2.4e-40 136.9 0.7 5.6e-40 135.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Glyco_hydro_cc PF11790.8 OAG24035.1 - 8.8e-68 228.4 0.0 1.1e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ferritin_2 PF13668.6 OAG24036.1 - 1.6e-06 28.3 0.1 3e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Zn_clus PF00172.18 OAG24037.1 - 1.6e-06 28.2 9.1 2.8e-06 27.4 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG24037.1 - 5.3e-06 25.5 0.0 8.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2306 PF10067.9 OAG24038.1 - 8.6e-15 55.2 10.2 1.9e-14 54.1 10.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) adh_short PF00106.25 OAG24039.1 - 3.3e-22 78.9 0.0 4.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24039.1 - 4e-14 52.7 0.0 5.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24039.1 - 7.5e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 KR domain HSF_DNA-bind PF00447.17 OAG24040.1 - 2.3e-29 101.8 0.8 3.7e-29 101.2 0.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.7 OAG24042.1 - 1.1e-05 25.2 1.2 2.3e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG24042.1 - 0.0023 17.8 0.3 0.0071 16.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain CutA1 PF03091.15 OAG24042.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Pribosyltran PF00156.27 OAG24043.1 - 3e-08 33.3 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RabGAP-TBC PF00566.18 OAG24044.1 - 1e-33 116.9 0.0 2.1e-33 115.8 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.26 OAG24045.1 - 2.7e-43 147.0 0.1 3e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG24045.1 - 5.3e-05 23.5 0.0 7.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OAG24045.1 - 0.00075 19.2 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG24045.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain BTB PF00651.31 OAG24046.1 - 1.9e-08 34.5 0.1 7.8e-08 32.5 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 OAG24046.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain SDP_N PF12278.8 OAG24046.1 - 0.13 12.4 1.0 0.25 11.5 1.0 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Inositol_P PF00459.25 OAG24047.1 - 4.4e-68 229.7 0.0 4.9e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Pectate_lyase_3 PF12708.7 OAG24048.1 - 2.1e-88 295.8 15.8 3.4e-79 265.7 1.4 2.6 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG24048.1 - 1.9e-06 27.4 1.5 0.041 13.6 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase 4HBT PF03061.22 OAG24049.1 - 1.7e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UFD1 PF03152.14 OAG24051.1 - 7.5e-28 97.1 0.0 1.6e-14 53.7 0.0 3.9 4 0 0 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 OAG24051.1 - 7.5e-07 29.3 2.0 8.3e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf_UBZ PF18439.1 OAG24051.1 - 3.4 7.3 6.5 20 4.9 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger F-box-like PF12937.7 OAG24052.1 - 0.031 14.1 0.1 0.085 12.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like DnaB PF00772.21 OAG24052.1 - 0.032 14.3 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain F-box PF00646.33 OAG24052.1 - 0.078 12.9 0.2 3 7.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Yip1 PF04893.17 OAG24053.1 - 1.8e-06 27.8 14.9 8.4e-06 25.6 14.9 2.0 1 1 0 1 1 1 1 Yip1 domain Cyto_heme_lyase PF01265.17 OAG24054.1 - 5.5e-117 390.5 0.1 6.6e-117 390.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DEAD PF00270.29 OAG24055.1 - 7.7e-29 100.7 0.0 1.6e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAG24055.1 - 9.7e-21 74.3 1.0 2.9e-20 72.8 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAG24055.1 - 3.3e-12 46.7 0.0 1.5e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 OAG24055.1 - 9.7e-07 29.2 0.1 1.9e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 OAG24055.1 - 2.2e-06 27.8 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fungal_trans PF04082.18 OAG24056.1 - 3.7e-73 245.8 0.2 5.4e-73 245.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG24056.1 - 0.00017 21.9 15.9 0.00083 19.7 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG24056.1 - 0.15 12.6 10.1 0.55 10.8 4.5 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Mob1_phocein PF03637.17 OAG24057.1 - 7.2e-24 84.7 0.2 1.3e-23 83.9 0.2 1.4 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.19 OAG24058.1 - 1.8e-47 161.2 0.2 2.6e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAG24058.1 - 7.1e-09 35.5 0.1 2.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAG24058.1 - 4e-06 26.8 0.1 0.057 13.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAG24058.1 - 0.0023 18.3 0.0 0.0064 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OAG24058.1 - 0.0034 17.0 0.3 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG24058.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 OAG24058.1 - 0.012 14.6 0.5 1.3 7.9 0.1 2.7 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OAG24058.1 - 0.014 15.1 0.2 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG24058.1 - 0.037 14.3 0.3 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG24058.1 - 0.038 14.5 1.1 0.13 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG24058.1 - 0.05 12.6 1.0 0.063 12.3 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 OAG24058.1 - 0.054 13.3 0.1 8 6.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 OAG24058.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 OAG24058.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OAG24058.1 - 0.1 13.1 0.1 0.5 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG24058.1 - 0.1 13.1 0.4 0.3 11.6 0.1 1.8 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 OAG24058.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OAG24058.1 - 0.13 12.0 0.7 0.51 10.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OAG24058.1 - 0.15 12.1 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 OAG24059.1 - 1e-118 397.1 27.8 1.8e-118 396.3 27.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG24059.1 - 1.9e-22 79.7 50.5 6.4e-17 61.5 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2781 PF10914.8 OAG24060.1 - 8.4e-40 136.6 7.8 9.6e-40 136.4 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ATP_synt_H PF05493.13 OAG24062.1 - 1.2e-22 80.1 2.1 1.4e-22 79.9 2.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Phage_holin_2_3 PF16080.5 OAG24062.1 - 0.17 11.7 0.6 0.17 11.7 0.6 1.6 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF4131 PF13567.6 OAG24062.1 - 0.21 11.2 1.3 0.23 11.1 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Arv1 PF04161.13 OAG24063.1 - 7.2e-70 235.4 0.0 9.1e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family Nucleoporin_N PF08801.11 OAG24064.1 - 4.1e-85 286.1 0.3 5.6e-85 285.7 0.3 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAG24064.1 - 4.2e-51 174.4 9.4 4.2e-51 174.4 9.4 1.6 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal YqeY PF09424.10 OAG24065.1 - 4.3e-26 91.7 2.3 5.1e-26 91.5 2.3 1.1 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 OAG24065.1 - 0.074 12.9 3.4 2.6 7.9 0.7 2.3 1 1 0 2 2 2 0 GatB domain AA_permease_2 PF13520.6 OAG24068.1 - 2.2e-52 178.3 36.3 2.8e-52 178.0 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG24068.1 - 5.1e-33 114.4 26.0 5.1e-33 114.4 26.0 1.6 2 0 0 2 2 2 1 Amino acid permease AgrD PF05931.11 OAG24068.1 - 0.26 11.3 2.2 0.27 11.3 0.2 2.1 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF3278 PF11683.8 OAG24068.1 - 3.6 7.7 6.3 0.55 10.3 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3328 PF11807.8 OAG24070.1 - 4.6e-24 85.4 0.1 8.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1344 PF07076.11 OAG24070.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Acetyltransf_7 PF13508.7 OAG24071.1 - 3e-08 34.0 0.0 6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG24071.1 - 3e-07 30.7 0.0 9e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG24071.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG24071.1 - 0.0072 16.3 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG24071.1 - 0.086 12.9 0.1 0.59 10.2 0.0 2.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.20 OAG24072.1 - 2.5e-31 109.2 0.0 3.4e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 OAG24073.1 - 2e-06 27.8 11.4 3.4e-06 27.1 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 OAG24075.1 - 1.7e-129 432.7 0.0 2e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alpha_Helical PF18489.1 OAG24079.1 - 0.0055 16.9 1.0 0.018 15.3 1.0 1.9 1 0 0 1 1 1 1 Alpha helical domain DUF2115 PF09888.9 OAG24079.1 - 0.78 10.3 4.2 0.47 11.0 0.1 2.7 2 2 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Thymidylat_synt PF00303.19 OAG24080.1 - 4.5e-106 353.9 0.0 5.2e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase NOG1_N PF17835.1 OAG24081.1 - 3.5e-49 166.8 1.4 5.6e-49 166.2 0.1 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAG24081.1 - 2e-27 94.9 1.9 2e-27 94.9 1.9 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAG24081.1 - 3.3e-24 84.4 0.2 7.1e-24 83.3 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAG24081.1 - 3.6e-16 59.3 0.0 1e-14 54.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG24081.1 - 4.3e-07 29.6 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG24081.1 - 0.00074 19.5 0.6 0.73 9.7 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase AAA_18 PF13238.6 OAG24081.1 - 0.087 13.4 0.6 0.73 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG24081.1 - 0.14 12.2 1.2 13 5.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 OAG24081.1 - 0.2 12.0 0.9 1.7 9.0 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain DUF1989 PF09347.10 OAG24082.1 - 4.6e-38 130.5 0.2 1.7e-27 96.1 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF1989) ArfGap PF01412.18 OAG24083.1 - 3.8e-34 117.3 0.9 6.5e-34 116.5 0.9 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.8 OAG24083.1 - 0.25 11.3 1.7 0.45 10.5 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) zf-RanBP PF00641.18 OAG24084.1 - 0.004 16.4 1.8 0.004 16.4 1.8 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 OAG24084.1 - 0.046 13.8 4.2 0.13 12.3 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon Pam17 PF08566.10 OAG24085.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.8 OAG24086.1 - 4.2e-19 68.6 0.7 4.3e-13 48.8 0.4 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24086.1 - 1.7e-07 31.3 11.5 2.7e-07 30.6 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rot1 PF10681.9 OAG24087.1 - 1.6e-92 308.8 1.1 1.9e-92 308.6 1.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 OAG24088.1 - 1e-33 116.8 0.0 3.7e-31 108.4 0.0 2.2 2 1 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 OAG24089.1 - 1.2e-15 56.9 0.1 1.4e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAG24089.1 - 0.0037 16.9 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 OAG24090.1 - 1.3e-28 99.9 1.4 1e-27 97.0 0.1 3.4 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OAG24090.1 - 5e-05 23.1 0.3 0.0002 21.2 0.2 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OAG24090.1 - 7.8e-05 23.1 2.0 0.0031 18.0 0.0 4.7 6 0 0 6 6 6 1 HEAT-like repeat RNA_polI_A14 PF08203.11 OAG24090.1 - 0.091 13.5 0.4 0.28 11.9 0.4 1.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 eIF3g PF12353.8 OAG24092.1 - 1.4e-43 148.3 6.2 2.2e-43 147.6 6.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAG24092.1 - 7.5e-19 67.3 0.0 1.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG24092.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG24092.1 - 0.031 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG24092.1 - 0.084 12.9 3.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif Glyco_trans_4_5 PF16994.5 OAG24092.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Pribosyltran PF00156.27 OAG24093.1 - 3.5e-17 62.4 0.1 5.7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG24093.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Tim17 PF02466.19 OAG24094.1 - 2.2e-27 95.6 4.7 2.9e-27 95.2 4.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_47 PF01532.20 OAG24095.1 - 9e-174 578.7 0.0 1.5e-173 577.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 OPT PF03169.15 OAG24097.1 - 4e-120 402.3 43.1 4.6e-120 402.1 43.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1056 PF06341.11 OAG24097.1 - 0.42 10.9 0.1 0.42 10.9 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) adh_short PF00106.25 OAG24098.1 - 2.3e-28 99.0 0.4 2.9e-28 98.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24098.1 - 8.3e-24 84.4 0.4 9.9e-24 84.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24098.1 - 1.2e-09 38.3 0.2 1.6e-09 38.0 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG24098.1 - 5.8e-05 23.1 0.0 0.00016 21.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG24098.1 - 0.0083 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family WD-3 PF09765.9 OAG24098.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 WD-repeat region Gpr1_Fun34_YaaH PF01184.19 OAG24099.1 - 4e-34 118.0 18.6 5.1e-34 117.7 18.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SID-1_RNA_chan PF13965.6 OAG24099.1 - 1.6 7.1 4.2 2 6.7 4.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TIM PF00121.18 OAG24100.1 - 1.7e-50 171.7 0.0 1.9e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MTHFR PF02219.17 OAG24101.1 - 9.2e-114 379.6 0.0 1.3e-113 379.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.16 OAG24103.1 - 1.5e-14 53.8 51.2 5.8e-09 35.3 19.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DoxD PF04173.13 OAG24103.1 - 0.0034 17.3 1.2 0.0084 16.0 1.2 1.6 1 0 0 1 1 1 1 TQO small subunit DoxD CTXphi_pIII-N1 PF16710.5 OAG24103.1 - 0.078 13.1 0.9 3.6 7.7 0.1 2.5 1 1 1 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII ORC4_C PF14629.6 OAG24104.1 - 1.2e-56 191.6 0.0 1.7e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAG24104.1 - 3.3e-16 60.1 0.0 1.4e-15 58.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG24104.1 - 1.8e-07 31.5 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG24104.1 - 1.4e-06 28.8 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG24104.1 - 4.8e-06 26.6 0.2 4.3e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.13 OAG24104.1 - 3.3e-05 23.2 0.0 5.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAG24104.1 - 0.0029 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain PIF1 PF05970.14 OAG24104.1 - 0.012 14.8 0.1 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase ATPase_2 PF01637.18 OAG24104.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAG24104.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 OAG24104.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OAG24104.1 - 0.038 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 OAG24104.1 - 0.043 13.5 0.1 0.098 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG24104.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 OAG24104.1 - 0.061 12.2 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) cobW PF02492.19 OAG24104.1 - 0.08 12.5 0.1 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OAG24104.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG24104.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OAG24104.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Lipase_GDSL PF00657.22 OAG24105.1 - 9.3e-14 51.9 0.1 1.2e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG24105.1 - 5.7e-05 23.6 4.5 0.00027 21.4 4.5 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_23 PF13489.6 OAG24106.1 - 2.7e-10 40.3 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG24106.1 - 3.7e-08 34.0 0.0 9.6e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG24106.1 - 2.1e-07 31.6 0.0 3.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG24106.1 - 3.9e-06 27.4 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG24106.1 - 0.22 11.0 0.2 0.55 9.7 0.2 1.7 1 1 0 1 1 1 0 Putative methyltransferase adh_short PF00106.25 OAG24107.1 - 1e-84 282.9 5.0 2.7e-46 157.5 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24107.1 - 6.8e-67 225.4 0.5 6.2e-35 120.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAG24107.1 - 1.5e-34 118.2 0.0 4.9e-34 116.5 0.0 2.0 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAG24107.1 - 5.2e-30 104.7 1.8 2.3e-14 53.7 0.3 2.3 2 0 0 2 2 2 2 KR domain Glucodextran_B PF09136.10 OAG24107.1 - 0.041 14.3 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Glucodextranase, domain B Epimerase PF01370.21 OAG24107.1 - 0.052 13.0 1.7 0.24 10.8 0.1 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Pterin_bind PF00809.22 OAG24108.1 - 1.9e-77 260.3 0.1 2.5e-77 259.9 0.1 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 OAG24108.1 - 1.9e-31 108.9 0.0 3.8e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 OAG24109.1 - 4.5e-56 190.6 1.2 6.3e-56 190.2 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG24109.1 - 2.3e-09 36.7 1.6 2.3e-09 36.7 1.6 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG24109.1 - 2.3e-05 23.6 0.8 5e-05 22.5 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 OAG24109.1 - 0.0013 18.0 1.5 0.0023 17.2 0.3 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Radial_spoke_3 PF06098.11 OAG24109.1 - 0.09 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Snf7 PF03357.21 OAG24113.1 - 0.00056 19.5 8.9 0.00056 19.5 8.9 2.5 1 1 2 3 3 3 1 Snf7 HK97-gp10_like PF04883.12 OAG24113.1 - 1.8 9.6 5.0 1.3 10.1 0.1 2.6 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component CBFD_NFYB_HMF PF00808.23 OAG24114.1 - 9.6e-18 64.2 0.8 1.8e-17 63.3 0.8 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG24114.1 - 0.00016 22.1 0.8 0.0012 19.2 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 EF-hand_13 PF17958.1 OAG24114.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain TFIID-31kDa PF02291.15 OAG24114.1 - 0.088 12.9 0.5 0.45 10.6 0.0 1.8 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 OAG24115.1 - 4.4e-68 229.5 0.0 6e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24115.1 - 2.5e-30 105.7 0.0 3.5e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG24115.1 - 4.4e-12 46.5 0.0 1.8e-11 44.5 0.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAG24115.1 - 2.4e-08 33.6 0.1 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 OAG24115.1 - 1.2e-07 32.0 0.0 6.4e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 OAG24115.1 - 0.0015 17.5 0.1 0.0034 16.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OAG24115.1 - 0.0016 18.1 0.2 0.4 10.3 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG24115.1 - 0.0057 16.6 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 OAG24115.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 OAG24115.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.17 OAG24116.1 - 2.8e-33 115.3 0.0 4.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.11 OAG24116.1 - 0.11 12.8 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) MaoC_dehydratas PF01575.19 OAG24117.1 - 2e-23 82.3 0.0 3.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAG24117.1 - 3.1e-09 37.1 0.0 3.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase HMG_CoA_synt_C PF08540.10 OAG24118.1 - 1.8e-109 365.7 0.5 2.4e-109 365.3 0.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OAG24118.1 - 1.3e-96 321.4 0.1 2.3e-96 320.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Synaptobrevin PF00957.21 OAG24119.1 - 0.0068 16.2 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin OAD_gamma PF04277.13 OAG24119.1 - 0.036 14.6 0.0 0.16 12.6 0.0 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Amidohydro_1 PF01979.20 OAG24120.1 - 2.4e-16 60.0 0.0 4.2e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG24120.1 - 4.8e-13 49.4 0.3 1.5e-10 41.2 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_3 PF00933.21 OAG24121.1 - 3.8e-65 220.4 0.0 4.9e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 OAG24121.1 - 1e-05 25.7 0.0 5.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 OAG24121.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.7 OAG24121.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 OAG24122.1 - 5.4e-35 121.3 0.0 1.2e-34 120.2 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 OAG24123.1 - 9.3e-61 205.3 0.0 1.3e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG24123.1 - 8.1e-47 159.7 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 OAG24124.1 - 5.5e-13 48.6 30.1 5.5e-13 48.6 30.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG24124.1 - 5e-10 39.3 5.7 5e-10 39.3 5.7 3.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAG24124.1 - 0.0017 17.3 5.5 0.0017 17.3 5.5 2.1 2 0 0 2 2 2 1 MFS_1 like family Glucosamine_iso PF01182.20 OAG24125.1 - 3.2e-20 73.0 0.0 5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NCA2 PF08637.10 OAG24126.1 - 1.5e-105 352.6 0.9 2.2e-105 352.0 0.9 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.22 OAG24127.1 - 7e-65 217.6 0.0 8.4e-65 217.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG24127.1 - 7e-34 116.6 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG24127.1 - 3.2e-13 49.5 0.0 5.2e-13 48.8 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG24127.1 - 1.4e-05 24.7 0.0 3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG24127.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAG24127.1 - 0.0035 17.3 0.1 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG24127.1 - 0.0042 17.1 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG24127.1 - 0.036 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG24127.1 - 0.045 13.3 0.0 0.24 10.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 OAG24127.1 - 0.11 13.0 0.0 7.8 6.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG24127.1 - 0.12 12.6 0.1 0.76 10.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF5540 PF17694.1 OAG24127.1 - 0.17 12.5 0.5 0.5 10.9 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5540) PI3_PI4_kinase PF00454.27 OAG24128.1 - 4.6e-54 183.9 0.0 9.2e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAG24128.1 - 4.9e-35 121.4 0.2 8.8e-35 120.5 0.2 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 OAG24128.1 - 1.5e-29 101.9 0.0 1.4e-28 98.8 0.0 2.9 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 OAG24128.1 - 3e-14 52.5 0.0 9.7e-14 50.9 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 OAG24128.1 - 0.0012 19.3 0.0 0.013 16.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3385 PF11865.8 OAG24128.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) DUF3631 PF12307.8 OAG24128.1 - 0.021 15.0 0.1 0.09 13.0 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) COX16 PF14138.6 OAG24129.1 - 2.9e-32 111.0 0.2 3.9e-32 110.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Ras PF00071.22 OAG24130.1 - 2.8e-41 140.8 0.0 1.9e-38 131.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG24130.1 - 8.8e-33 113.1 0.0 1.4e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG24130.1 - 4.5e-12 45.8 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG24130.1 - 0.00016 21.8 0.0 0.0004 20.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG24130.1 - 0.0023 18.3 0.0 0.0059 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 OAG24130.1 - 0.0028 17.1 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAG24130.1 - 0.011 15.2 0.0 0.037 13.5 0.0 1.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OAG24130.1 - 0.048 13.4 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OAG24130.1 - 0.055 13.2 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAG24130.1 - 0.085 12.8 0.4 0.37 10.7 0.1 2.1 2 1 1 3 3 3 0 RsgA GTPase FMN_dh PF01070.18 OAG24131.1 - 8.3e-121 403.3 0.1 1e-120 403.0 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG24131.1 - 3.5e-23 81.6 0.0 6.8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG24131.1 - 4.2e-08 32.7 0.0 8.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG24131.1 - 0.00014 21.0 0.6 0.00026 20.1 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG24131.1 - 0.044 13.2 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 OAG24131.1 - 0.073 12.5 1.4 1.2 8.5 0.2 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 OAG24131.1 - 0.095 12.0 0.1 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pro_CA PF00484.19 OAG24131.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbonic anhydrase Med27 PF11571.8 OAG24132.1 - 1.1e-13 51.4 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Nic96 PF04097.14 OAG24134.1 - 4.8e-201 669.4 0.0 6.3e-201 669.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 PFK PF00365.20 OAG24135.1 - 4.9e-190 629.8 6.5 4.3e-109 364.2 2.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 OAG24135.1 - 0.027 14.1 0.1 0.15 11.7 0.1 2.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Tau95_N PF17682.1 OAG24135.1 - 0.15 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Tau95 Triple barrel domain adh_short PF00106.25 OAG24136.1 - 7.9e-26 90.7 0.0 9.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24136.1 - 2.4e-21 76.4 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24136.1 - 0.062 13.2 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.16 OAG24137.1 - 1.4e-20 73.5 34.5 6.9e-13 48.2 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24137.1 - 5.6e-14 51.8 19.8 9e-14 51.2 19.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 OAG24138.1 - 1.1e-43 148.9 0.0 1.7e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG24138.1 - 1.4e-13 50.4 0.0 3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAG24138.1 - 9.8e-08 32.3 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG24138.1 - 6.1e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG24138.1 - 7.9e-07 29.6 0.0 3.9e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 OAG24138.1 - 1.6e-06 27.9 2.5 4.2e-06 26.6 2.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 OAG24138.1 - 1.6e-05 25.2 0.2 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OAG24138.1 - 6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAG24138.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAG24138.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 OAG24138.1 - 0.0018 18.8 0.0 0.028 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG24138.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAG24138.1 - 0.0055 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAG24138.1 - 0.0078 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG24138.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 OAG24138.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAG24138.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 OAG24138.1 - 0.018 14.7 0.1 0.064 12.9 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 OAG24138.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAG24138.1 - 0.021 14.6 0.0 0.092 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 OAG24138.1 - 0.026 14.0 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG24138.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG24138.1 - 0.039 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAG24138.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAG24138.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG24138.1 - 0.066 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAG24138.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 OAG24138.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Cep57_MT_bd PF06657.13 OAG24139.1 - 0.0076 16.7 1.4 5.7 7.5 0.1 3.3 3 0 0 3 3 3 2 Centrosome microtubule-binding domain of Cep57 DUF5340 PF17275.2 OAG24139.1 - 0.023 14.8 0.4 0.07 13.3 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5340) MobC PF05713.11 OAG24139.1 - 0.041 14.4 1.4 0.66 10.5 0.0 3.4 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) MFS_1 PF07690.16 OAG24141.1 - 3.1e-17 62.5 31.4 3.1e-17 62.5 31.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG24141.1 - 0.00095 17.6 1.1 0.00095 17.6 1.1 2.1 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family YwiC PF14256.6 OAG24141.1 - 0.66 10.3 12.5 1 9.7 1.7 2.8 3 0 0 3 3 3 0 YwiC-like protein YqzM PF14141.6 OAG24141.1 - 0.88 9.7 4.4 30 4.7 0.0 2.8 2 0 0 2 2 2 0 YqzM-like protein Dioxygenase_C PF00775.21 OAG24142.1 - 3.8e-08 33.0 0.1 6.8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase DEC-1_N PF04625.13 OAG24142.1 - 0.16 10.9 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NmrA PF05368.13 OAG24143.1 - 1.5e-23 83.6 0.0 2.1e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG24143.1 - 5.2e-21 75.4 0.0 1.8e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG24143.1 - 1.7e-11 44.1 0.2 1.8e-07 30.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG24143.1 - 1.6e-05 24.9 0.2 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG24143.1 - 2e-05 24.9 0.4 3.4e-05 24.1 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG24143.1 - 0.0013 17.9 0.6 0.0028 16.8 0.6 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG24143.1 - 0.0025 17.9 0.3 0.0047 17.0 0.3 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 OAG24143.1 - 0.0026 16.9 0.1 0.0045 16.1 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG24143.1 - 0.0032 16.7 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 OAG24143.1 - 0.0055 17.1 0.1 0.017 15.6 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG24143.1 - 0.0078 15.2 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG24143.1 - 0.0088 15.5 0.1 0.4 10.0 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OAG24143.1 - 0.01 16.4 0.5 0.023 15.3 0.5 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 OAG24143.1 - 0.025 14.7 0.5 0.042 14.0 0.5 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 OAG24143.1 - 0.042 14.1 0.5 0.093 13.0 0.5 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 OAG24143.1 - 0.043 13.3 0.7 0.084 12.3 0.7 1.5 1 1 0 1 1 1 0 short chain dehydrogenase SUR7 PF06687.12 OAG24144.1 - 0.041 13.5 2.3 0.066 12.8 1.4 1.5 1 1 0 1 1 1 0 SUR7/PalI family EF-hand_1 PF00036.32 OAG24145.1 - 5.2e-27 91.3 12.1 3.7e-07 29.2 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAG24145.1 - 8e-24 83.9 13.8 3.1e-14 53.2 1.6 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAG24145.1 - 1.7e-20 71.1 6.0 6.9e-05 22.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAG24145.1 - 1.7e-18 65.2 10.2 1.5e-06 27.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OAG24145.1 - 1.2e-13 50.6 11.5 9.9e-05 22.1 0.6 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG24145.1 - 2.5e-06 27.8 0.0 0.0048 17.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAG24145.1 - 6.7e-06 26.0 6.8 0.0033 17.4 0.4 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAG24145.1 - 0.033 14.4 0.7 0.13 12.5 0.6 2.1 1 1 0 1 1 1 0 Dockerin type I domain Anillin PF08174.11 OAG24145.1 - 0.07 13.6 0.0 2.3 8.6 0.0 2.1 1 1 0 2 2 2 0 Cell division protein anillin EF-hand_9 PF14658.6 OAG24145.1 - 0.094 13.1 0.1 4.3 7.7 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain PMBR PF09373.10 OAG24145.1 - 0.16 12.2 0.0 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF1770 PF08589.10 OAG24146.1 - 1.1e-32 112.9 0.1 1.5e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SNF2_N PF00176.23 OAG24147.1 - 1.3e-61 208.2 0.0 2.1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG24147.1 - 4.5e-15 55.9 0.0 9.3e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG24147.1 - 2e-08 34.4 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG24147.1 - 5.6e-05 22.4 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAG24147.1 - 0.00028 20.7 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RPN13_C PF16550.5 OAG24147.1 - 0.039 14.1 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 UCH-binding domain SWI2_SNF2 PF18766.1 OAG24147.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase RNR_inhib PF08591.10 OAG24148.1 - 1.5e-25 90.5 0.6 5.4e-25 88.8 0.0 2.1 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor MARVEL PF01284.23 OAG24149.1 - 3.7e-05 23.8 3.4 6.7e-05 23.0 3.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_A24 PF01478.18 OAG24149.1 - 0.00072 19.9 1.1 0.0029 18.0 1.1 1.9 1 1 0 1 1 1 1 Type IV leader peptidase family PMP1_2 PF08114.11 OAG24149.1 - 0.015 15.0 0.5 0.015 15.0 0.5 1.9 2 0 0 2 2 2 0 ATPase proteolipid family LapA_dom PF06305.11 OAG24149.1 - 0.083 12.7 0.5 0.083 12.7 0.5 2.9 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain LysM PF01476.20 OAG24150.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 OAG24150.1 - 0.035 13.9 2.0 0.036 13.9 0.2 1.9 2 0 0 2 2 2 0 UBA-like domain Ribosomal_S8 PF00410.19 OAG24151.1 - 5.6e-22 78.0 0.3 9e-22 77.4 0.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 AAA_2 PF07724.14 OAG24152.1 - 2.3e-47 161.3 0.0 1.1e-45 155.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG24152.1 - 1.2e-33 115.2 1.3 1.2e-33 115.2 1.3 3.8 3 1 2 5 5 5 1 AAA lid domain AAA PF00004.29 OAG24152.1 - 6.4e-27 94.6 0.0 3.9e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG24152.1 - 6.6e-25 87.0 0.3 2.4e-24 85.2 0.3 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG24152.1 - 2e-15 57.0 0.3 1.1e-09 38.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG24152.1 - 2.8e-12 47.1 1.4 9.1e-05 22.8 0.0 4.8 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.6 OAG24152.1 - 5.6e-10 39.9 12.7 1.3e-05 25.7 0.1 5.4 4 3 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 OAG24152.1 - 3.7e-09 36.5 0.0 7.5e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 OAG24152.1 - 7.3e-07 29.8 0.4 0.11 13.1 0.0 4.5 4 1 0 4 4 3 2 AAA domain Clp_N PF02861.20 OAG24152.1 - 8.8e-07 29.0 0.9 0.032 14.4 0.1 3.9 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 OAG24152.1 - 1.4e-06 27.9 0.0 0.0052 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG24152.1 - 3.5e-06 26.9 0.0 0.071 12.8 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 OAG24152.1 - 4.2e-06 26.8 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAG24152.1 - 1.2e-05 25.5 0.1 0.26 11.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 OAG24152.1 - 1.4e-05 24.6 0.2 0.14 11.5 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OAG24152.1 - 2.6e-05 24.0 0.0 0.43 10.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 OAG24152.1 - 3.1e-05 24.3 0.2 0.74 10.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 OAG24152.1 - 4.7e-05 23.4 0.0 5.7 6.8 0.1 4.2 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG24152.1 - 6e-05 23.4 0.0 0.48 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.11 OAG24152.1 - 0.00011 22.0 0.0 0.68 9.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAG24152.1 - 0.00014 21.8 0.0 0.53 10.2 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 OAG24152.1 - 0.0002 21.3 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OAG24152.1 - 0.00037 20.3 0.0 0.59 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OAG24152.1 - 0.00041 20.9 1.3 0.53 10.8 0.0 3.5 4 0 0 4 4 4 1 ABC transporter RuvB_N PF05496.12 OAG24152.1 - 0.00043 20.1 1.6 4.3 7.1 0.9 4.4 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 OAG24152.1 - 0.00058 20.2 1.8 0.33 11.3 0.4 4.0 5 1 0 5 5 3 1 AAA domain AAA_29 PF13555.6 OAG24152.1 - 0.0021 17.8 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG24152.1 - 0.0022 17.1 0.0 0.024 13.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 OAG24152.1 - 0.0043 16.4 0.0 0.45 9.8 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Torsin PF06309.11 OAG24152.1 - 0.0055 16.8 0.0 0.031 14.4 0.0 2.2 3 0 0 3 3 1 1 Torsin NACHT PF05729.12 OAG24152.1 - 0.006 16.5 0.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 OAG24152.1 - 0.0062 16.8 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 OAG24152.1 - 0.0088 15.7 0.0 2.5 7.7 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 OAG24152.1 - 0.009 15.6 0.3 1.4 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAG24152.1 - 0.01 15.8 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 OAG24152.1 - 0.026 14.5 0.0 8.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain CbiA PF01656.23 OAG24152.1 - 0.067 13.2 0.0 30 4.7 0.0 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 OAG24152.1 - 0.1 12.6 0.0 5.3 7.0 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Spc7 PF08317.11 OAG24152.1 - 0.3 9.9 12.2 0.76 8.6 12.2 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 OAG24152.1 - 0.34 11.4 0.0 0.34 11.4 0.0 4.9 5 1 0 5 5 3 0 AAA domain Cep57_CLD_2 PF14197.6 OAG24152.1 - 2.9 8.1 13.0 3 8.0 8.9 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 OAG24152.1 - 8.7 4.1 5.2 1.3 6.8 1.3 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 OAG24153.1 - 1.6e-36 126.0 19.9 1.6e-36 126.0 19.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24153.1 - 6.4e-07 28.6 7.6 6.4e-07 28.6 7.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Sec63 PF02889.16 OAG24156.1 - 4e-16 58.9 0.0 3.7e-15 55.8 0.0 2.4 2 1 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.31 OAG24156.1 - 2.3e-15 56.4 0.2 6.7e-15 55.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain RRN3 PF05327.11 OAG24156.1 - 1.4 7.4 3.6 2 6.8 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 OAG24157.1 - 4.5e-50 170.5 0.0 2.7e-47 161.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24157.1 - 2.1e-29 102.6 0.0 3.4e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OAG24157.1 - 0.0017 17.4 0.1 0.0026 16.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 OAG24157.1 - 0.0039 16.6 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG24157.1 - 0.071 11.9 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OAG24157.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OAG24158.1 - 1e-63 214.8 0.0 2e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Mem_trans PF03547.18 OAG24158.1 - 3.7e-50 170.4 1.7 7e-50 169.5 1.7 1.4 1 0 0 1 1 1 1 Membrane transport protein Choline_kin_N PF04428.14 OAG24158.1 - 7.9e-15 54.3 0.0 1.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 OAG24158.1 - 5.1e-06 26.6 0.3 5.1e-06 26.6 0.3 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DASH_Dad2 PF08654.10 OAG24158.1 - 0.17 12.3 1.4 1.1 9.8 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad2 Tmemb_185A PF10269.9 OAG24158.1 - 2.8 7.6 6.4 5 6.7 0.9 2.4 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein TPR_20 PF14561.6 OAG24158.1 - 4.6 7.7 7.1 0.88 10.0 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Mis12 PF05859.12 OAG24159.1 - 1e-40 139.0 0.0 1.9e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein Pkinase PF00069.25 OAG24160.1 - 9.6e-51 172.7 0.0 5.4e-50 170.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24160.1 - 1.7e-19 70.2 0.0 2.7e-18 66.2 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4148 PF13663.6 OAG24160.1 - 0.13 12.5 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) ParG PF09274.10 OAG24161.1 - 0.22 11.7 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 ParG Aminotran_3 PF00202.21 OAG24162.1 - 1.4e-74 251.2 0.0 3e-74 250.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III SRP19 PF01922.17 OAG24163.1 - 3.1e-35 121.0 0.0 5.3e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Asp PF00026.23 OAG24164.1 - 2.4e-63 214.5 13.5 2.9e-63 214.2 13.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG24164.1 - 1.4e-06 28.7 6.1 0.00087 19.6 1.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG24164.1 - 2.7e-05 24.7 2.3 0.0021 18.6 0.3 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG24164.1 - 0.039 14.5 1.9 0.18 12.4 0.2 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DEAD PF00270.29 OAG24165.1 - 4.2e-32 111.3 0.2 5.5e-29 101.2 0.2 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG24165.1 - 1.2e-23 83.5 0.0 4.4e-23 81.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG24165.1 - 1.1e-05 25.6 0.0 4.5e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAG24165.1 - 0.0055 15.5 0.1 0.11 11.3 0.0 2.4 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PIGA PF08288.12 OAG24166.1 - 2.1e-47 159.7 2.3 2.1e-47 159.6 0.8 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAG24166.1 - 4.2e-28 98.5 1.1 6.5e-28 97.8 0.6 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAG24166.1 - 3.6e-26 91.7 0.0 5.8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG24166.1 - 5.9e-24 85.0 0.4 1.3e-23 83.9 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG24166.1 - 2.2e-12 47.7 0.0 7e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAG24166.1 - 3.2e-05 24.2 0.0 0.00015 22.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OAG24166.1 - 0.00013 22.0 0.1 0.00028 21.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 OAG24166.1 - 0.0083 15.8 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain DUF3455 PF11937.8 OAG24167.1 - 3.2e-41 141.3 1.3 4.3e-41 140.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2761 PF10959.8 OAG24167.1 - 0.0038 17.2 0.3 0.94 9.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2761) NDUF_B12 PF08122.12 OAG24167.1 - 0.015 15.4 0.0 0.054 13.5 0.0 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF2990 PF11693.8 OAG24167.1 - 0.092 12.9 0.1 0.092 12.9 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2990) CASP_C PF08172.12 OAG24169.1 - 1.6e-91 306.2 0.0 1.6e-91 306.2 0.0 4.2 3 1 1 5 5 5 2 CASP C terminal CtIP_N PF10482.9 OAG24169.1 - 0.012 15.7 0.2 0.012 15.7 0.2 5.5 4 2 1 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain Cortex-I_coil PF09304.10 OAG24169.1 - 0.015 15.5 4.9 0.015 15.5 4.9 5.4 3 1 2 6 6 6 0 Cortexillin I, coiled coil Glyco_transf_36 PF06165.11 OAG24169.1 - 0.19 11.1 1.3 0.36 10.2 1.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 36 ZapB PF06005.12 OAG24169.1 - 0.31 11.5 0.0 0.31 11.5 0.0 7.2 5 3 1 6 6 6 0 Cell division protein ZapB COX16 PF14138.6 OAG24169.1 - 7.6 7.1 23.0 5.6 7.5 0.0 5.2 4 0 0 4 4 4 0 Cytochrome c oxidase assembly protein COX16 Vps39_2 PF10367.9 OAG24170.1 - 4e-08 33.7 0.0 3.8e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 OAG24170.1 - 7e-07 29.2 0.2 6.3e-05 22.9 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_1 PF10366.9 OAG24170.1 - 0.0033 17.7 0.3 1.9 8.8 0.1 2.9 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Prefoldin_2 PF01920.20 OAG24171.1 - 9.9e-24 83.3 4.6 1.5e-23 82.8 4.6 1.3 1 0 0 1 1 1 1 Prefoldin subunit AATF-Che1 PF13339.6 OAG24171.1 - 0.034 14.8 1.7 0.17 12.6 0.0 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor YojJ PF10372.9 OAG24171.1 - 0.1 12.7 3.0 5.3 7.2 1.1 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF5065 PF16723.5 OAG24171.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DUF2730 PF10805.8 OAG24171.1 - 0.13 12.4 2.1 0.22 11.6 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 OAG24171.1 - 0.6 10.1 3.2 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 OAG24171.1 - 0.92 9.6 6.1 6 7.0 2.8 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Takusan PF04822.13 OAG24171.1 - 1.2 9.1 0.1 1.2 9.1 0.1 2.4 2 1 0 2 2 2 0 Takusan Spore_III_AF PF09581.10 OAG24171.1 - 2.3 8.2 8.4 2.3 8.2 7.5 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) CENP-H PF05837.12 OAG24171.1 - 7.7 7.0 10.2 61 4.1 0.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MFS_1 PF07690.16 OAG24172.1 - 6.3e-40 137.2 39.1 8.1e-40 136.8 36.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24172.1 - 1.4e-12 47.2 6.8 1.4e-12 47.2 6.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3915 PF13054.6 OAG24172.1 - 2.1 8.3 3.7 5.5 7.0 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Anoctamin PF04547.12 OAG24172.1 - 5.8 5.6 7.8 0.32 9.8 0.7 2.4 4 0 0 4 4 4 0 Calcium-activated chloride channel CoA_binding_3 PF13727.6 OAG24173.1 - 0.024 14.7 1.2 0.024 14.7 1.2 1.6 2 0 0 2 2 2 0 CoA-binding domain 2OG-FeII_Oxy PF03171.20 OAG24174.1 - 5.2e-14 52.6 0.0 8.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Arf PF00025.21 OAG24175.1 - 1.5e-40 138.5 0.0 1.3e-25 89.9 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAG24175.1 - 2.2e-14 53.4 0.0 5.3e-08 32.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG24175.1 - 1.3e-11 44.3 0.0 4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG24175.1 - 2.2e-11 44.0 0.0 5.6e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAG24175.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAG24175.1 - 1.6e-06 27.7 0.0 2.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG24175.1 - 9.6e-06 25.7 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG24175.1 - 0.00062 19.4 0.0 0.04 13.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF4630 PF15443.6 OAG24175.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) FeoB_N PF02421.18 OAG24175.1 - 0.13 11.8 0.1 0.27 10.7 0.1 1.7 2 1 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 OAG24175.1 - 0.17 12.4 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Na_Ca_ex PF01699.24 OAG24176.1 - 5.5e-23 81.6 40.1 1.5e-13 51.0 11.6 3.4 3 1 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 OAG24176.1 - 2.1e-15 57.1 8.1 2.1e-15 57.1 8.1 4.2 4 0 0 4 4 4 1 Inner membrane component domain zf-RING_2 PF13639.6 OAG24177.1 - 2.9e-13 49.9 4.5 4.9e-13 49.2 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG24177.1 - 1.9e-11 43.5 1.6 3.9e-11 42.5 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG24177.1 - 9.3e-08 31.8 4.7 1.5e-07 31.1 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG24177.1 - 3.2e-07 30.1 3.7 5.5e-07 29.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG24177.1 - 1.8e-06 28.1 4.8 5.5e-06 26.6 4.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG24177.1 - 1.9e-05 24.5 2.2 3.1e-05 23.8 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG24177.1 - 2.1e-05 24.3 4.1 4e-05 23.4 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG24177.1 - 0.0012 18.7 1.3 0.002 18.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG24177.1 - 0.0027 17.7 0.7 0.0079 16.2 0.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAG24177.1 - 0.0087 15.8 3.1 0.016 15.0 3.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAG24177.1 - 0.021 14.8 6.4 0.043 13.8 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 OAG24177.1 - 0.23 11.4 3.0 0.43 10.5 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OAG24177.1 - 0.27 11.6 1.9 0.46 10.8 1.9 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 OAG24177.1 - 1.2 9.1 3.0 1.2 9.1 1.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PEP_mutase PF13714.6 OAG24178.1 - 4.7e-05 22.9 0.0 5.3e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DASH_Ask1 PF08655.10 OAG24178.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Ask1 PEP_mutase PF13714.6 OAG24179.1 - 3.6e-23 82.3 0.0 3.9e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG24179.1 - 5.1e-06 25.3 0.1 5.8e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OAG24179.1 - 0.044 13.2 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.16 OAG24180.1 - 1.5e-25 89.9 12.9 4.3e-25 88.4 13.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24180.1 - 2.7e-10 39.7 7.0 4.4e-10 39.0 7.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 OAG24180.1 - 0.0025 16.4 8.2 0.031 12.8 4.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein DUF2651 PF10852.8 OAG24182.1 - 0.1 13.2 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) EthD PF07110.11 OAG24183.1 - 8.4e-09 36.5 0.3 1e-08 36.2 0.3 1.1 1 0 0 1 1 1 1 EthD domain SH3_1 PF00018.28 OAG24184.1 - 3.2e-25 87.5 0.0 5.7e-12 45.1 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 OAG24184.1 - 1.3e-16 60.1 0.1 1.4e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OAG24184.1 - 5.8e-14 51.5 0.0 2.3e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 OAG24184.1 - 3.7e-11 43.0 0.0 8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 OAG24184.1 - 0.00011 22.1 0.2 0.00021 21.2 0.2 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 OAG24185.1 - 1.1e-24 87.4 6.3 6.4e-14 52.0 0.6 2.4 2 1 1 3 3 3 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAG24185.1 - 0.0011 19.0 0.5 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 OAG24185.1 - 0.095 13.2 0.2 0.33 11.5 0.1 2.0 1 1 1 2 2 2 0 PCI domain EAP30 PF04157.16 OAG24186.1 - 3.4e-44 150.9 0.4 4.3e-44 150.6 0.4 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 OAG24186.1 - 1.4e-22 79.7 0.0 2.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 OAG24186.1 - 4.8e-22 77.1 2.0 4.8e-22 77.1 2.0 2.5 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 OAG24186.1 - 0.00017 21.6 4.6 0.0037 17.3 0.3 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 OAG24186.1 - 0.0021 17.3 2.4 0.0021 17.3 2.4 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 OAG24186.1 - 0.1 12.6 6.5 0.13 12.3 0.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon Ephrin_rec_like PF07699.13 OAG24186.1 - 2.9 7.7 8.3 0.19 11.5 2.7 1.9 2 0 0 2 2 2 0 Putative ephrin-receptor like F-box-like_2 PF13013.6 OAG24187.1 - 0.0082 16.1 0.1 0.067 13.2 0.1 2.2 1 1 0 1 1 1 1 F-box-like domain Inhibitor_I66 PF16850.5 OAG24188.1 - 2.8e-10 40.3 0.0 1e-09 38.4 0.0 1.7 1 1 1 2 2 2 1 Peptidase inhibitor I66 Trypsin PF00089.26 OAG24190.1 - 1.1e-63 215.0 1.8 1.3e-63 214.8 1.8 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OAG24190.1 - 5e-07 30.7 3.8 7.1e-07 30.2 3.8 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2418 PF10332.9 OAG24191.1 - 1.1e-32 112.4 0.1 1.7e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF1206 PF06724.11 OAG24191.1 - 0.099 12.7 4.5 0.23 11.6 4.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) ATP-synt_F PF01990.17 OAG24192.1 - 9.3e-33 112.4 0.0 1.1e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 OAG24192.1 - 0.15 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase E1_DerP2_DerF2 PF02221.15 OAG24193.1 - 1.3e-27 96.9 0.0 1.7e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 OAG24193.1 - 0.041 14.6 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig domain CopC PF04234.12 OAG24193.1 - 0.14 13.2 0.0 0.21 12.6 0.0 1.4 1 1 0 1 1 1 0 CopC domain DLH PF01738.18 OAG24194.1 - 6.5e-06 25.8 0.1 3.8e-05 23.3 0.1 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAG24194.1 - 6.7e-05 22.6 0.3 9.8e-05 22.1 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAG24194.1 - 0.0018 17.0 0.2 0.047 12.3 0.1 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 OAG24194.1 - 0.0027 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OAG24194.1 - 0.037 13.5 0.3 0.72 9.3 0.3 2.6 2 1 1 3 3 3 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.26 OAG24195.1 - 5.9e-15 55.4 0.0 8.2e-14 51.7 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG24195.1 - 1.4e-13 52.0 0.0 2.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 OAG24195.1 - 1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.12 OAG24195.1 - 2.2e-05 24.3 0.0 4.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FlgT_M PF16539.5 OAG24195.1 - 0.054 13.6 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain MFS_1 PF07690.16 OAG24196.1 - 4.7e-44 150.8 41.8 4.7e-44 150.8 41.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24196.1 - 2.5e-16 59.6 0.1 2.5e-16 59.6 0.1 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG24196.1 - 1.7e-06 27.6 7.4 1.7e-06 27.6 7.4 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB PM0188 PF11477.8 OAG24197.1 - 0.043 13.0 0.3 0.063 12.4 0.3 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 DUF3431 PF11913.8 OAG24198.1 - 5.2e-10 39.5 0.4 2.6e-09 37.2 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2070 PF09843.9 OAG24198.1 - 0.023 13.0 3.7 0.043 12.1 3.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssN PF17555.2 OAG24198.1 - 6.9 6.0 10.9 2.4 7.5 1.0 3.0 2 1 1 3 3 3 0 Type VI secretion system, TssN COesterase PF00135.28 OAG24199.1 - 7.7e-64 216.4 0.0 1.1e-63 216.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family NUFIP2 PF15293.6 OAG24199.1 - 0.0091 14.9 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Abhydrolase_3 PF07859.13 OAG24199.1 - 0.011 15.6 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG24199.1 - 0.12 11.6 0.1 0.23 10.7 0.0 1.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SMN PF06003.12 OAG24199.1 - 6.4 6.0 6.0 89 2.2 6.8 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) UCH PF00443.29 OAG24201.1 - 9e-51 172.8 0.1 1.4e-50 172.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG24201.1 - 2.4e-26 93.1 6.0 8.8e-21 74.8 0.4 2.4 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG24201.1 - 7.9e-06 26.1 1.1 7.9e-06 26.1 1.1 2.8 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 OAG24201.1 - 0.0004 19.9 0.5 5 6.5 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3150 PF11348.8 OAG24201.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) zf-HIT PF04438.16 OAG24201.1 - 9.4 6.2 9.7 18 5.3 0.2 3.0 2 0 0 2 2 2 0 HIT zinc finger Glyco_hydro_61 PF03443.14 OAG24202.1 - 4.2e-59 199.9 0.1 5.2e-59 199.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PH PF00169.29 OAG24203.1 - 0.00053 20.5 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 PH domain WSC PF01822.19 OAG24204.1 - 8.3e-15 54.8 7.5 1.7e-14 53.8 7.5 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 OAG24204.1 - 1.4e-06 27.6 0.6 2.7e-06 26.7 0.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 OAG24204.1 - 0.00024 20.9 0.1 0.0005 19.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Ost5 PF05251.12 OAG24204.1 - 0.0023 18.2 0.7 0.04 14.2 0.5 2.3 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit 5 TMEM51 PF15345.6 OAG24204.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 BatD PF13584.6 OAG24204.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Adeno_E3_CR2 PF02439.15 OAG24204.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MGC-24 PF05283.11 OAG24204.1 - 0.033 14.7 0.1 0.033 14.7 0.1 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_60s PF00428.19 OAG24204.1 - 0.051 14.2 0.8 0.051 14.2 0.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TMEM154 PF15102.6 OAG24204.1 - 0.057 13.3 0.7 0.12 12.3 0.0 1.8 2 1 0 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 OAG24204.1 - 0.065 13.6 1.1 0.098 13.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Peptidase_M56 PF05569.11 OAG24204.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Trp_oprn_chp PF09534.10 OAG24204.1 - 0.11 12.3 3.5 0.077 12.8 0.4 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 OAG24204.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4718 PF15842.5 OAG24204.1 - 0.28 11.0 0.8 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Gln-synt_C PF00120.24 OAG24206.1 - 1.5e-30 106.4 0.0 6.2e-30 104.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 OAG24206.1 - 2.5e-12 47.2 0.1 1.3e-11 44.8 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Glyco_hydro_72 PF03198.14 OAG24207.1 - 1.7e-129 431.6 7.4 2.3e-129 431.2 7.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAG24207.1 - 2.5e-18 66.5 4.0 6.6e-18 65.2 4.0 1.8 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.15 OAG24208.1 - 0 1374.2 0.0 0 1373.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAG24208.1 - 1.3e-41 142.0 0.5 4e-41 140.4 0.5 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 OAG24209.1 - 1.2e-36 126.7 0.0 1.4e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG24209.1 - 0.025 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CDP-OH_P_transf PF01066.21 OAG24210.1 - 3e-12 47.1 0.9 5e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 OAG24211.1 - 4.7e-169 562.5 0.0 5.9e-169 562.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.6 OAG24211.1 - 0.018 14.9 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG24211.1 - 0.094 12.9 0.6 0.2 11.8 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Whi5 PF08528.11 OAG24212.1 - 7.8e-09 35.0 0.7 1.7e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 Whi5 like DUF2070 PF09843.9 OAG24213.1 - 0.86 7.8 5.4 1 7.6 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gar1 PF04410.14 OAG24215.1 - 2.3e-37 128.2 0.0 2.8e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 OAG24216.1 - 1.1e-31 110.2 0.0 5e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG24216.1 - 5.1e-17 61.8 0.4 1.1e-16 60.8 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OAG24216.1 - 1.9e-13 50.3 0.2 4.7e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 OAG24216.1 - 9e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain Pyrid_ox_like PF16242.5 OAG24217.1 - 4.5e-21 75.0 0.0 8.2e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like GST_N_2 PF13409.6 OAG24217.1 - 2.2e-19 69.5 0.0 1.3e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG24217.1 - 2.4e-19 69.5 1.2 6.5e-19 68.1 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG24217.1 - 1.7e-11 44.3 0.1 4.3e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CH PF00307.31 OAG24217.1 - 8.2e-08 32.4 0.0 1.9e-05 24.8 0.0 3.3 3 0 0 3 3 3 1 Calponin homology (CH) domain Putative_PNPOx PF01243.20 OAG24217.1 - 1.3e-07 31.7 0.0 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase IQ PF00612.27 OAG24217.1 - 0.00023 20.6 16.6 0.0014 18.3 1.5 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif GST_C_2 PF13410.6 OAG24217.1 - 0.0011 18.9 0.1 0.0033 17.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0175 PF03683.13 OAG24218.1 - 0.026 14.2 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) TMEM247 PF15444.6 OAG24219.1 - 0.36 10.8 1.4 0.84 9.6 1.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Prok-RING_1 PF14446.6 OAG24220.1 - 0.073 13.0 2.8 0.15 12.1 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ATG16 PF08614.11 OAG24220.1 - 0.1 12.8 8.7 6.3 7.0 5.7 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Mu-like_Com PF10122.9 OAG24220.1 - 0.4 10.2 2.2 0.92 9.0 2.2 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com GREB1 PF15782.5 OAG24220.1 - 0.49 7.5 5.5 0.65 7.1 5.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 OAG24220.1 - 0.98 7.9 5.1 1.3 7.5 5.1 1.2 1 0 0 1 1 1 0 Macoilin family zf-RING_UBOX PF13445.6 OAG24221.1 - 4e-05 23.6 0.2 8.3e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG24221.1 - 5.1e-05 23.5 1.3 0.00023 21.4 0.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAG24221.1 - 0.00012 22.3 0.2 0.00028 21.1 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG24221.1 - 0.0012 18.7 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG24221.1 - 0.0023 17.5 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAG24221.1 - 0.059 13.1 0.7 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAG24221.1 - 0.16 12.2 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAG24221.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OAG24221.1 - 0.31 11.1 0.6 0.75 9.9 0.6 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG24221.1 - 0.33 10.8 1.5 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WRNPLPNID PF15017.6 OAG24221.1 - 0.73 10.7 7.1 0.11 13.4 2.2 2.1 2 0 0 2 2 1 0 Putative WW-binding domain and destruction box Glyco_hydro_32N PF00251.20 OAG24222.1 - 3.1e-46 158.3 5.8 1e-45 156.6 5.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAG24222.1 - 7.3e-28 97.5 0.1 1.3e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 OAG24222.1 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 OAG24222.1 - 0.074 13.1 2.4 0.15 12.1 0.1 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Thioredoxin PF00085.20 OAG24224.1 - 1.8e-63 211.0 4.4 7.3e-32 109.4 0.1 4.2 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 OAG24224.1 - 9.2e-49 165.9 0.2 6.7e-34 117.4 0.1 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 OAG24224.1 - 3.9e-10 39.3 1.0 7.1e-10 38.5 0.3 1.9 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 OAG24224.1 - 1.1e-08 35.1 0.2 0.0043 17.2 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 OAG24224.1 - 4.9e-08 33.2 0.0 0.038 14.3 0.0 4.3 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG24224.1 - 5.8e-08 33.2 0.6 0.0022 18.5 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG24224.1 - 7.4e-07 28.8 0.2 0.015 14.7 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAG24224.1 - 1.6e-05 24.8 0.2 0.13 12.2 0.1 2.9 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 OAG24224.1 - 5.7e-05 22.9 2.5 0.085 12.6 0.0 3.6 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 OAG24224.1 - 0.00014 22.0 0.2 1.8 8.7 0.0 3.9 3 1 0 3 3 3 2 ERp29, N-terminal domain Apolipoprotein PF01442.18 OAG24224.1 - 0.0055 16.6 10.0 0.0096 15.8 10.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain RIFIN PF02009.16 OAG24224.1 - 3.5 7.4 5.2 7 6.4 5.2 1.5 1 0 0 1 1 1 0 Rifin COG5 PF10392.9 OAG24225.1 - 5.1e-43 146.4 0.3 5.1e-43 146.4 0.3 2.6 3 1 0 3 3 3 1 Golgi transport complex subunit 5 AAA PF00004.29 OAG24226.1 - 5e-19 69.0 0.0 1.3e-18 67.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG24226.1 - 3.8e-05 24.1 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG24226.1 - 0.00066 19.7 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG24226.1 - 0.00092 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAG24226.1 - 0.0067 15.8 0.6 0.032 13.6 0.1 2.2 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 OAG24226.1 - 0.008 16.5 0.1 0.049 13.9 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 OAG24226.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG24226.1 - 0.064 13.4 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DnaB_C PF03796.15 OAG24226.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Vps36_ESCRT-II PF11605.8 OAG24226.1 - 0.081 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_11 PF13086.6 OAG24226.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG24226.1 - 0.096 13.2 0.0 0.32 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG24226.1 - 0.097 12.0 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAG24226.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG24226.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 OAG24227.1 - 1.7e-41 141.9 0.0 2.4e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG24227.1 - 3.2e-28 98.3 0.4 5.8e-27 94.2 0.5 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG24227.1 - 0.0023 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rhomboid PF01694.22 OAG24228.1 - 1.7e-17 63.8 13.4 1.7e-17 63.8 13.4 1.9 1 1 1 2 2 2 1 Rhomboid family Fcf2 PF08698.11 OAG24229.1 - 2.6 8.5 8.1 0.5 10.8 0.2 3.4 3 1 1 4 4 4 0 Fcf2 pre-rRNA processing Bromodomain PF00439.25 OAG24230.1 - 1.2e-20 73.3 0.6 3.2e-20 72.0 0.6 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAG24230.1 - 6.8e-06 26.0 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated SPARC_Ca_bdg PF10591.9 OAG24230.1 - 0.11 12.8 0.5 0.38 11.1 0.5 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region VanZ PF04892.12 OAG24231.1 - 1.3e-05 25.8 0.6 1.8e-05 25.4 0.6 1.2 1 0 0 1 1 1 1 VanZ like family Ribosomal_S26e PF01283.19 OAG24232.1 - 9e-52 174.1 8.0 1.1e-51 173.8 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 OAG24232.1 - 0.023 14.7 0.5 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 OAG24232.1 - 0.085 12.7 0.4 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF1918 PF08940.11 OAG24232.1 - 0.094 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) SF1-HH PF16275.5 OAG24232.1 - 0.18 12.2 2.4 0.28 11.5 2.4 1.5 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain CBS PF00571.28 OAG24233.1 - 3.2e-33 114.0 9.6 1.6e-09 38.1 0.0 5.1 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 OAG24233.1 - 2.3e-09 37.1 0.0 6.2e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DUF3748 PF12566.8 OAG24233.1 - 0.054 13.5 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) HAD PF12710.7 OAG24233.1 - 0.12 12.7 0.1 0.55 10.6 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Importin_rep_4 PF18808.1 OAG24234.1 - 1.9e-36 124.2 3.9 3.2e-35 120.3 1.7 3.5 2 1 1 3 3 3 1 Importin repeat Importin_rep_5 PF18816.1 OAG24234.1 - 3.8e-24 84.7 1.7 1.7e-23 82.6 1.7 2.3 1 0 0 1 1 1 1 Importin repeat HEAT_EZ PF13513.6 OAG24234.1 - 3.3e-20 72.2 12.2 8.4e-11 42.1 0.7 8.5 6 2 3 9 9 9 3 HEAT-like repeat HEAT PF02985.22 OAG24234.1 - 2e-18 64.9 13.2 0.00024 21.1 0.1 11.3 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 OAG24234.1 - 2.1e-17 63.3 13.1 1.1e-05 25.7 0.1 7.5 5 2 2 7 7 6 3 HEAT repeats Importin_rep_6 PF18829.1 OAG24234.1 - 6.3e-13 48.8 3.5 1.5e-11 44.3 0.2 3.8 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 OAG24234.1 - 9.9e-10 38.9 0.2 0.017 15.7 0.0 6.0 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAG24234.1 - 8.3e-08 32.4 0.9 0.0015 18.6 0.0 4.4 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAG24234.1 - 1e-06 28.1 1.1 1e-06 28.1 1.1 4.3 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 OAG24234.1 - 1.1e-06 28.6 0.7 0.15 12.0 0.1 6.0 6 1 1 7 7 6 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 OAG24234.1 - 4e-06 26.7 0.1 0.0014 18.4 0.1 4.2 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 OAG24234.1 - 1.4e-05 24.8 1.0 0.024 14.2 0.1 4.3 5 1 1 6 6 6 1 CLASP N terminal DUF4042 PF13251.6 OAG24234.1 - 0.00041 20.1 0.3 3.4 7.3 0.0 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 OAG24234.1 - 0.0013 18.9 0.9 0.52 10.5 0.3 4.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 OAG24234.1 - 0.0027 18.0 0.0 0.83 10.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion TFCD_C PF12612.8 OAG24234.1 - 0.024 14.5 4.0 22 4.8 0.2 5.0 5 2 0 5 5 5 0 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 OAG24234.1 - 0.037 13.6 7.3 2.5 7.6 0.1 4.4 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 OAG24234.1 - 0.094 12.0 5.3 0.42 9.9 0.1 3.5 3 1 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 OAG24234.1 - 5.8 7.1 13.1 5.8 7.1 0.0 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat AAA PF00004.29 OAG24235.1 - 2.9e-42 144.2 0.0 4.8e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAG24235.1 - 1.2e-29 102.1 0.3 8.8e-29 99.3 0.3 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAG24235.1 - 2.6e-23 81.8 4.7 2.6e-23 81.8 4.7 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAG24235.1 - 3.9e-06 26.6 0.1 1.3e-05 24.9 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 OAG24235.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG24235.1 - 2.5e-05 24.7 0.0 0.00024 21.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG24235.1 - 3.9e-05 23.7 0.0 0.00018 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG24235.1 - 5.2e-05 23.6 0.0 0.012 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 OAG24235.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAG24235.1 - 0.00016 21.9 0.0 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAG24235.1 - 0.00022 20.5 0.0 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OAG24235.1 - 0.00033 20.9 0.1 0.02 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OAG24235.1 - 0.0004 19.6 0.0 0.0015 17.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG24235.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG24235.1 - 0.00085 19.9 0.2 0.0032 18.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 OAG24235.1 - 0.0017 18.5 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAG24235.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAG24235.1 - 0.0046 16.5 0.0 0.038 13.5 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 OAG24235.1 - 0.013 16.0 0.1 0.054 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG24235.1 - 0.024 14.0 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Phage_GPO PF05929.11 OAG24235.1 - 0.027 14.1 0.3 0.047 13.3 0.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Torsin PF06309.11 OAG24235.1 - 0.037 14.1 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 OAG24235.1 - 0.055 13.2 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OAG24235.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAG24235.1 - 0.066 12.8 0.0 0.65 9.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 OAG24235.1 - 0.081 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein USP8_dimer PF08969.11 OAG24235.1 - 0.088 13.0 4.8 0.064 13.5 3.1 1.7 2 0 0 2 2 1 0 USP8 dimerisation domain Cytidylate_kin PF02224.18 OAG24235.1 - 0.12 12.1 0.1 0.53 10.0 0.1 2.1 3 0 0 3 3 2 0 Cytidylate kinase NACHT PF05729.12 OAG24235.1 - 0.12 12.3 0.0 0.64 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 OAG24235.1 - 0.2 10.5 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ATPase_2 PF01637.18 OAG24235.1 - 0.31 10.9 1.1 1.2 8.9 0.0 2.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prefoldin_2 PF01920.20 OAG24236.1 - 3.3e-20 72.0 6.7 3.3e-20 72.0 6.7 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin PF02996.17 OAG24236.1 - 0.00047 20.1 2.5 0.00047 20.1 2.5 2.3 2 1 0 2 2 2 1 Prefoldin subunit DivIC PF04977.15 OAG24236.1 - 0.00073 19.3 9.8 0.046 13.5 0.1 2.9 3 0 0 3 3 3 2 Septum formation initiator Rh5 PF18515.1 OAG24236.1 - 0.0022 17.4 4.7 0.0029 17.0 4.7 1.1 1 0 0 1 1 1 1 Rh5 coiled-coil domain Spc24 PF08286.11 OAG24236.1 - 0.014 15.7 7.9 0.25 11.6 0.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF5643 PF18705.1 OAG24236.1 - 0.036 14.0 1.3 0.051 13.6 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) APG6_N PF17675.1 OAG24236.1 - 0.037 14.6 0.6 0.037 14.6 0.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 OAG24236.1 - 0.044 12.7 8.1 0.037 12.9 7.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 OAG24236.1 - 0.077 13.4 6.9 2.1 8.8 0.6 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HDV_ag PF01517.18 OAG24236.1 - 0.092 12.5 2.0 0.44 10.3 0.1 2.1 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen Laminin_II PF06009.12 OAG24236.1 - 0.17 11.9 9.7 0.51 10.4 7.5 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 OAG24236.1 - 0.68 10.0 8.1 0.28 11.2 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.13 OAG24236.1 - 0.94 9.6 10.3 0.28 11.3 3.3 2.5 1 1 2 3 3 3 0 DivIVA protein YabA PF06156.13 OAG24236.1 - 1.4 9.6 6.2 1.6 9.4 1.0 2.3 2 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 OAG24236.1 - 1.6 8.5 8.2 15 5.3 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NPV_P10 PF05531.12 OAG24236.1 - 2.1 8.9 9.0 0.95 10.0 0.7 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 OAG24236.1 - 2.5 8.3 9.3 19 5.4 9.3 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SAM_2 PF07647.17 OAG24238.1 - 4.7e-08 33.0 0.1 9.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG24238.1 - 1.1e-05 25.8 0.3 3.3e-05 24.2 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HemN_C PF06969.16 OAG24238.1 - 0.055 13.5 1.4 0.78 9.8 0.2 2.9 3 0 0 3 3 3 0 HemN C-terminal domain IGR PF09597.10 OAG24238.1 - 0.082 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif DUF4508 PF14969.6 OAG24238.1 - 0.11 12.8 0.2 0.28 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) FRB_dom PF08771.11 OAG24238.1 - 0.12 12.8 0.2 0.4 11.1 0.2 1.9 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Zn_clus PF00172.18 OAG24239.1 - 3.5e-11 43.0 10.9 8.3e-11 41.8 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG24239.1 - 8.3e-06 25.0 1.5 2e-05 23.8 1.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Opy2 PF09463.10 OAG24239.1 - 5 7.5 9.3 0.85 10.0 3.4 2.7 2 0 0 2 2 2 0 Opy2 protein MFS_1 PF07690.16 OAG24240.1 - 1.2e-33 116.5 26.2 2.8e-33 115.3 26.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily QRPTase_C PF01729.19 OAG24241.1 - 7.5e-53 178.8 0.0 1e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAG24241.1 - 2.9e-22 78.5 0.0 1e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Glyco_hydro_16 PF00722.21 OAG24241.1 - 1.6e-07 30.9 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 baeRF_family11 PF18855.1 OAG24241.1 - 0.21 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 Adenylsucc_synt PF00709.21 OAG24242.1 - 2.1e-174 580.4 0.3 3.6e-174 579.6 0.1 1.4 2 0 0 2 2 2 1 Adenylosuccinate synthetase MFS_1 PF07690.16 OAG24242.1 - 3.3e-33 115.1 30.8 4.7e-33 114.6 30.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.11 OAG24242.1 - 0.13 12.1 0.2 0.41 10.4 0.2 1.9 1 0 0 1 1 1 0 ATPase proteolipid family PBP PF01161.20 OAG24243.1 - 4.4e-13 49.7 0.1 6.5e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DEC-1_N PF04625.13 OAG24243.1 - 0.25 10.3 3.2 0.43 9.6 3.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPP_enzyme_N PF02776.18 OAG24244.1 - 8.6e-33 113.4 0.0 1.6e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG24244.1 - 2.6e-20 72.5 0.0 5.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG24244.1 - 3.3e-13 49.7 0.0 6.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAG24244.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ApbA_C PF08546.11 OAG24245.1 - 4.1e-26 91.6 0.3 1.6e-24 86.5 0.4 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG24245.1 - 9.5e-25 87.0 0.0 3.3e-24 85.3 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pkinase PF00069.25 OAG24247.1 - 3e-64 216.9 0.0 4.2e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24247.1 - 2.5e-45 154.8 0.0 4e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG24247.1 - 1.1e-09 38.0 0.0 2.5e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAG24247.1 - 0.012 14.5 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAG24247.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_3 PF18016.1 OAG24247.1 - 0.088 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) APH PF01636.23 OAG24247.1 - 0.093 12.6 0.6 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tyrosinase PF00264.20 OAG24248.1 - 1.2e-45 156.5 3.7 1.3e-45 156.4 2.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG24248.1 - 7.7e-24 84.7 0.0 3e-16 60.2 0.0 2.7 2 1 1 3 3 3 2 Tyosinase C-terminal domain zf-H2C2 PF09337.10 OAG24249.1 - 1e-14 54.4 2.6 1.8e-14 53.7 2.6 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 OAG24249.1 - 6.1e-12 45.5 0.6 1e-11 44.7 0.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 OAG24249.1 - 5.1e-05 23.5 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG24249.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CCDC73 PF15818.5 OAG24249.1 - 0.33 8.8 0.2 0.46 8.3 0.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Mog1 PF04603.12 OAG24250.1 - 1.7e-37 128.9 0.0 3.1e-37 128.0 0.0 1.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein zf-C2H2_jaz PF12171.8 OAG24251.1 - 1.5e-08 34.7 2.6 2.7e-08 33.9 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG24251.1 - 0.00013 22.2 1.0 0.00023 21.4 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 OAG24251.1 - 0.0058 16.4 0.2 0.012 15.4 0.2 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF2175 PF09943.9 OAG24251.1 - 0.17 12.2 2.6 0.14 12.4 0.8 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Aconitase PF00330.20 OAG24252.1 - 4.4e-151 504.0 0.0 5.5e-151 503.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG24252.1 - 3.9e-45 153.4 0.0 7.3e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Exo_endo_phos PF03372.23 OAG24252.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SprT-like PF10263.9 OAG24253.1 - 6.1e-37 125.9 0.5 1.1e-36 125.1 0.5 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 OAG24253.1 - 1.2e-09 37.9 4.1 2.4e-09 36.9 4.1 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 OAG24253.1 - 0.014 15.5 1.5 0.031 14.4 1.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF4379 PF14311.6 OAG24253.1 - 0.083 13.3 1.7 0.31 11.4 1.7 2.0 1 0 0 1 1 1 0 Probable Zinc-ribbon domain IDO PF01231.18 OAG24254.1 - 0.017 14.0 0.2 0.027 13.3 0.2 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase K_oxygenase PF13434.6 OAG24255.1 - 8.8e-13 48.1 0.0 4.3e-10 39.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG24255.1 - 5.4e-12 45.6 0.0 5.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG24255.1 - 7.3e-11 41.8 0.0 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG24255.1 - 2.8e-10 39.3 0.0 5.3e-07 28.4 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG24255.1 - 4e-08 33.4 0.1 1.7e-06 28.2 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG24255.1 - 9.4e-05 22.1 0.0 0.0097 15.5 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG24255.1 - 9.7e-05 22.4 0.4 0.81 9.7 0.1 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAG24255.1 - 0.00023 20.5 0.0 0.003 16.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAG24255.1 - 0.027 15.0 0.1 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAG24255.1 - 0.08 11.5 0.1 0.23 10.0 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 OAG24255.1 - 0.19 10.7 0.4 8.2 5.4 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Ureidogly_lyase PF04115.12 OAG24256.1 - 8.3e-74 247.4 0.0 1.1e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase eIF2A PF08662.11 OAG24258.1 - 5.4e-80 267.9 0.0 2.8e-79 265.5 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAG24258.1 - 0.0021 18.8 1.1 17 6.5 0.0 4.9 3 2 1 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 OAG24258.1 - 0.63 10.1 3.4 84 3.3 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Rubella_Capsid PF05750.11 OAG24258.1 - 2.5 7.7 20.4 4.2 6.9 20.4 1.3 1 0 0 1 1 1 0 Rubella capsid protein KGG PF10685.9 OAG24259.1 - 1.5e-22 79.1 19.2 7.8e-09 35.5 0.1 4.8 5 0 0 5 5 5 4 Stress-induced bacterial acidophilic repeat motif UDG PF03167.19 OAG24260.1 - 1.9e-20 73.4 0.0 3.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ThuA PF06283.11 OAG24261.1 - 2.9e-47 161.6 0.0 3.2e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation Trypsin PF00089.26 OAG24262.1 - 1.8e-62 211.1 4.7 2.2e-62 210.8 4.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OAG24262.1 - 5.4e-08 33.9 3.6 1.2e-07 32.8 3.6 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Sial-lect-inser PF09264.10 OAG24262.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion p450 PF00067.22 OAG24264.1 - 3e-67 227.3 0.0 3.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_r4_2 PF08281.12 OAG24266.1 - 5.9e-10 38.7 0.7 0.00027 20.5 0.3 3.5 3 0 0 3 3 3 2 Sigma-70, region 4 Myb_DNA-binding PF00249.31 OAG24266.1 - 3.6e-07 30.3 0.5 0.038 14.2 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG24266.1 - 2.2e-05 24.6 2.6 0.017 15.4 0.3 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Sigma70_ECF PF07638.11 OAG24266.1 - 0.00016 21.7 0.2 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 ECF sigma factor Sigma70_r4 PF04545.16 OAG24266.1 - 0.0005 19.5 1.6 0.29 10.7 0.4 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_23 PF13384.6 OAG24266.1 - 0.0008 19.1 4.2 0.75 9.7 0.1 3.6 3 2 0 3 3 3 2 Homeodomain-like domain GerE PF00196.19 OAG24266.1 - 0.0019 17.7 0.1 4.5 6.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 OAG24266.1 - 0.045 13.3 0.2 0.91 9.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MADF_DNA_bdg PF10545.9 OAG24266.1 - 0.1 13.0 1.8 1.1 9.7 0.1 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SGT1 PF07093.11 OAG24267.1 - 1.1e-77 261.9 19.4 5.1e-76 256.4 0.1 2.2 1 1 1 2 2 2 2 SGT1 protein WLM PF08325.10 OAG24268.1 - 9.1e-26 91.1 0.0 1.8e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAG24268.1 - 3.3e-09 37.1 0.5 6.3e-09 36.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RING_10 PF16685.5 OAG24268.1 - 0.016 15.3 2.3 0.044 13.9 2.3 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Di19 PF05605.12 OAG24268.1 - 2.8 8.3 9.1 7.8 6.9 0.2 3.4 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RanBP PF00641.18 OAG24268.1 - 3.3 7.1 12.7 0.037 13.3 2.9 2.5 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.7 OAG24268.1 - 3.9 7.6 8.3 11 6.1 8.3 1.8 1 0 0 1 1 1 0 Double zinc ribbon Aldedh PF00171.22 OAG24269.1 - 1.2e-183 610.9 0.0 1.4e-183 610.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG24269.1 - 0.004 16.3 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AA_permease_2 PF13520.6 OAG24270.1 - 8.8e-43 146.7 49.4 1.1e-42 146.4 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG24270.1 - 2.8e-16 59.2 43.4 3.8e-16 58.8 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease Neurensin PF14927.6 OAG24270.1 - 0.61 9.8 3.6 0.53 10.0 0.5 2.6 2 1 0 2 2 2 0 Neurensin DUF3445 PF11927.8 OAG24271.1 - 3.1e-74 249.4 0.5 3.7e-74 249.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ribonuc_L-PSP PF01042.21 OAG24272.1 - 1.5e-19 70.2 0.0 1.7e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans_2 PF11951.8 OAG24273.1 - 5.2e-28 97.9 7.6 7.2e-28 97.5 7.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24273.1 - 4.4e-07 29.9 7.6 4.4e-07 29.9 7.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain peroxidase PF00141.23 OAG24274.1 - 7.7e-32 110.8 0.0 9.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF1799 PF08809.11 OAG24274.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) BLOC1_2 PF10046.9 OAG24275.1 - 0.14 12.5 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCCH_4 PF18044.1 OAG24276.1 - 0.00032 20.4 3.0 0.00059 19.6 3.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG24276.1 - 0.0007 19.4 1.7 0.0012 18.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG24276.1 - 0.0012 18.8 5.0 0.0022 18.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Nucleoporin_FG PF13634.6 OAG24276.1 - 0.0063 17.3 166.9 1.3 10.0 32.1 7.0 2 1 3 5 5 5 2 Nucleoporin FG repeat region zf-CCCH_2 PF14608.6 OAG24276.1 - 0.25 11.9 7.6 0.61 10.6 7.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Gpi1 PF05024.15 OAG24277.1 - 2.3e-77 259.3 8.3 3.5e-77 258.7 8.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) BTB PF00651.31 OAG24278.1 - 3.7e-08 33.6 0.1 1.6e-07 31.5 0.0 1.9 1 1 0 2 2 2 1 BTB/POZ domain Methyltransf_23 PF13489.6 OAG24279.1 - 1.6e-21 76.8 0.0 2.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG24279.1 - 2.9e-09 36.9 0.0 6.2e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG24279.1 - 2.5e-08 34.5 0.0 5.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG24279.1 - 3e-07 31.1 0.0 1.2e-06 29.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG24279.1 - 2e-05 25.2 0.0 6.5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG24279.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 OAG24279.1 - 0.0032 16.4 0.0 0.024 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MTS PF05175.14 OAG24279.1 - 0.0066 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG24279.1 - 0.0082 15.5 0.0 0.027 13.8 0.0 1.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 OAG24279.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 OAG24279.1 - 0.016 14.5 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAG24279.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_15 PF09445.10 OAG24279.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAG24279.1 - 0.26 10.6 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ApoO PF09769.9 OAG24280.1 - 3.2e-37 127.4 0.6 4.8e-36 123.6 0.1 2.2 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.20 OAG24281.1 - 2.3e-124 416.2 0.0 3e-124 415.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OAG24281.1 - 0.046 14.0 0.4 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Effector protein Peptidase_M50B PF13398.6 OAG24281.1 - 0.27 10.8 0.2 0.42 10.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ANAPC1 PF12859.7 OAG24282.1 - 2e-33 115.7 1.8 2e-33 115.7 1.8 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 UBA2_C PF16195.5 OAG24283.1 - 5.5 7.8 7.7 4.6 8.0 0.1 2.8 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus GTP_EFTU PF00009.27 OAG24284.1 - 9.5e-11 41.6 0.0 3.5e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG24284.1 - 0.057 13.3 1.3 10 6.0 0.1 2.6 2 1 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 OAG24284.1 - 0.074 12.8 0.9 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OAG24284.1 - 0.34 10.4 1.4 26 4.3 0.0 3.4 4 0 0 4 4 4 0 Ferrous iron transport protein B zf-C2H2 PF00096.26 OAG24285.1 - 0.0061 16.9 4.0 0.42 11.2 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG24285.1 - 0.014 16.2 2.7 5.6 8.1 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Cys_Met_Meta_PP PF01053.20 OAG24286.1 - 1.7e-31 109.1 0.0 2.4e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG24286.1 - 0.0055 15.9 0.0 0.083 12.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II DUF1633 PF07794.11 OAG24287.1 - 0.015 13.6 1.2 0.019 13.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF572 PF04502.13 OAG24287.1 - 0.57 9.7 12.5 0.91 9.1 12.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) NPV_P10 PF05531.12 OAG24287.1 - 2 8.9 9.9 11 6.6 0.1 3.7 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Phage_HK97_TLTM PF06120.11 OAG24287.1 - 2.4 7.2 10.4 0.19 10.9 1.8 2.3 1 1 1 2 2 2 0 Tail length tape measure protein MPS2 PF17060.5 OAG24287.1 - 3.2 6.9 11.0 0.26 10.5 4.9 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 SlyX PF04102.12 OAG24287.1 - 3.2 8.4 25.6 0.23 12.1 5.0 4.3 3 2 1 4 4 4 0 SlyX TMF_DNA_bd PF12329.8 OAG24287.1 - 4.8 7.3 20.1 0.74 9.9 4.0 3.9 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 OAG24287.1 - 5.9 6.9 9.4 1.7 8.6 0.4 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PCMT PF01135.19 OAG24288.1 - 2.2e-69 233.4 0.0 2.8e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 OAG24288.1 - 3.4e-08 34.1 0.0 6.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG24288.1 - 3.8e-07 30.0 0.0 5e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG24288.1 - 7.8e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG24288.1 - 9.6e-05 23.0 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG24288.1 - 0.0001 21.8 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG24288.1 - 0.00039 20.3 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG24288.1 - 0.00093 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.10 OAG24288.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 OAG24288.1 - 0.0057 16.1 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OAG24288.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 OAG24288.1 - 0.026 14.6 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 OAG24288.1 - 0.028 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.20 OAG24288.1 - 0.038 13.1 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 OAG24288.1 - 0.064 14.0 0.1 0.14 12.9 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAG24288.1 - 0.075 14.1 0.0 0.24 12.4 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain CMAS PF02353.20 OAG24288.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Nrap_D4 PF17405.2 OAG24289.1 - 4.2e-62 209.3 0.0 7.3e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 OAG24289.1 - 3.7e-58 195.9 2.1 1.9e-57 193.5 0.7 2.4 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 OAG24289.1 - 6.2e-49 166.0 0.0 1.5e-48 164.7 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 OAG24289.1 - 9.4e-48 161.8 0.1 4.7e-47 159.6 0.0 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 OAG24289.1 - 1.5e-47 161.6 0.1 3.6e-47 160.4 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 OAG24289.1 - 6e-29 101.0 0.0 1.2e-28 100.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 SDA1 PF05285.12 OAG24289.1 - 9.1 5.6 10.2 14 4.9 10.2 1.2 1 0 0 1 1 1 0 SDA1 COesterase PF00135.28 OAG24290.1 - 4.9e-61 207.2 0.0 5.9e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG24290.1 - 7e-11 42.4 0.2 3.5e-10 40.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG24290.1 - 0.00021 22.0 0.0 0.0004 21.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG24290.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG24290.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 OAG24290.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase adh_short PF00106.25 OAG24291.1 - 5.7e-35 120.6 0.0 7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24291.1 - 4.1e-28 98.5 0.0 7.4e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24291.1 - 0.00019 21.4 0.1 0.006 16.5 0.1 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG24291.1 - 0.0021 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG24291.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG24291.1 - 0.16 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 OAG24292.1 - 9.8e-75 252.0 0.0 1.2e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 OAG24293.1 - 4.3e-30 105.2 0.0 5.1e-29 101.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG24293.1 - 5e-14 53.4 1.1 7e-14 52.9 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG24293.1 - 6.5e-13 48.5 0.0 9.7e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG24293.1 - 0.00023 20.0 0.0 0.00091 18.0 0.0 1.8 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 OAG24293.1 - 0.00036 20.6 0.0 0.00075 19.6 0.0 1.5 2 0 0 2 2 2 1 TAP-like protein Mito_carr PF00153.27 OAG24294.1 - 6.8e-65 215.0 0.0 1.8e-21 75.9 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OAG24294.1 - 0.0087 15.2 2.7 0.01 15.0 0.1 2.2 3 0 0 3 3 3 1 Gammaproteobacterial serine protease F-box-like PF12937.7 OAG24295.1 - 1.6e-07 31.1 0.1 3.2e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG24295.1 - 3.8e-05 23.4 0.1 7.4e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Qn_am_d_aII PF14930.6 OAG24295.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Cpn60_TCP1 PF00118.24 OAG24296.1 - 1e-152 509.3 6.2 1.2e-152 509.1 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box PF00646.33 OAG24297.1 - 0.079 12.9 1.2 0.35 10.8 1.2 2.2 1 1 0 1 1 1 0 F-box domain Ank_4 PF13637.6 OAG24298.1 - 3e-11 43.6 0.0 0.00013 22.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG24298.1 - 6.8e-10 39.0 0.4 0.049 14.0 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG24298.1 - 8e-09 36.0 0.0 0.002 18.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG24298.1 - 1.2e-05 25.3 0.2 0.057 14.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat TPR_12 PF13424.6 OAG24298.1 - 7.3e-05 23.0 7.5 0.00031 21.0 2.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank PF00023.30 OAG24298.1 - 0.0012 19.2 0.0 5.5 7.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat TPR_19 PF14559.6 OAG24298.1 - 0.69 10.5 8.4 0.91 10.1 0.5 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG24298.1 - 1.1 9.2 3.6 3.9 7.5 0.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAG24299.1 - 3e-15 56.0 30.8 4.5e-15 55.4 30.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG24299.1 - 1.7e-10 40.8 6.2 1.7e-10 40.8 6.2 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAG24300.1 - 3e-22 79.0 57.7 3e-22 79.0 57.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 OAG24301.1 - 3.5e-58 193.5 5.0 3.4e-21 75.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAG24302.1 - 3.7e-41 140.4 0.0 4.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG24302.1 - 5.2e-13 49.3 0.0 7.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG24302.1 - 5.4e-05 22.7 0.0 6.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG24302.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG24302.1 - 0.0028 17.2 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 OAG24302.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Flocculin_t3 PF13928.6 OAG24302.1 - 0.09 13.3 0.4 0.22 12.1 0.4 1.6 1 0 0 1 1 1 0 Flocculin type 3 repeat PRK PF00485.18 OAG24302.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PAS_9 PF13426.7 OAG24303.1 - 4.7e-26 91.1 0.2 2.1e-15 56.9 0.0 4.1 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 OAG24303.1 - 1.3e-19 70.3 0.0 3e-11 43.5 0.0 4.1 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 OAG24303.1 - 4.2e-15 55.0 8.9 8.9e-15 54.0 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAG24303.1 - 2.5e-14 53.3 0.0 1.7e-06 28.0 0.0 4.4 4 1 0 4 4 4 3 PAS fold PAS_11 PF14598.6 OAG24303.1 - 1.8e-07 31.3 0.0 0.0022 18.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAG24303.1 - 2.6e-06 27.7 0.0 0.012 15.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 OAG24303.1 - 0.0057 17.3 0.0 0.57 10.9 0.0 3.3 3 0 0 3 3 3 1 PAS fold Cytochrom_c3_2 PF14537.6 OAG24303.1 - 0.055 13.9 2.2 0.18 12.3 2.2 1.9 1 0 0 1 1 1 0 Cytochrome c3 Ribosomal_S2 PF00318.20 OAG24304.1 - 6e-67 225.0 0.2 1.8e-65 220.2 0.2 2.3 1 1 0 1 1 1 1 Ribosomal protein S2 DsbC PF11412.8 OAG24304.1 - 0.033 14.2 0.0 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Disulphide bond corrector protein DsbC LDcluster4 PF18306.1 OAG24304.1 - 0.054 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 SLOG cluster4 family CRAL_TRIO PF00650.20 OAG24305.1 - 1.3e-43 148.4 0.0 2.1e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG24305.1 - 2.7e-15 56.3 1.2 4e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG24305.1 - 9.1e-08 32.4 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 OAG24305.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) DASH_Dam1 PF08653.10 OAG24306.1 - 2.6e-26 91.2 1.5 3.6e-26 90.7 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ytp1 PF10355.9 OAG24307.1 - 9.8e-117 389.1 13.1 1.9e-116 388.2 13.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG24307.1 - 4.1e-25 87.6 5.6 4.1e-25 87.6 5.6 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) ELYS PF13934.6 OAG24308.1 - 5.1e-61 206.4 1.5 6.1e-61 206.2 1.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly OmdA PF13376.6 OAG24309.1 - 1.5e-12 47.3 0.1 2.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Tyrosinase PF00264.20 OAG24310.1 - 1.6e-16 61.3 0.6 2e-16 60.9 0.6 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Toxin_YhaV PF11663.8 OAG24310.1 - 0.21 11.6 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system zf-RING_4 PF14570.6 OAG24311.1 - 0.027 14.2 0.3 0.046 13.5 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Phage_holin_3_7 PF05449.11 OAG24312.1 - 2.6 8.1 14.5 0.18 11.8 6.7 2.8 1 1 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 Glyco_transf_90 PF05686.12 OAG24314.1 - 5.6e-38 130.9 1.3 8.6e-38 130.3 1.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG24314.1 - 0.03 14.7 0.1 0.065 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DnaJ PF00226.31 OAG24315.1 - 1.2e-21 76.6 0.4 1.2e-21 76.6 0.4 2.8 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAG24315.1 - 2.6e-12 46.7 12.3 4.4e-11 42.8 4.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG24315.1 - 4.4e-10 39.6 8.9 3.4e-08 33.6 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG24315.1 - 6.5e-06 26.4 7.2 0.0018 18.6 1.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG24315.1 - 7.7e-06 26.3 5.7 0.02 15.7 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG24315.1 - 0.0011 19.3 8.3 0.19 12.3 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-LYAR PF08790.11 OAG24315.1 - 0.097 12.6 0.3 0.097 12.6 0.3 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 OAG24315.1 - 0.67 10.4 5.4 17 5.9 1.2 3.6 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-PHD-like PF15446.6 OAG24315.1 - 1.4 8.5 11.0 0.39 10.3 6.8 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C2H2_6 PF13912.6 OAG24315.1 - 2.6 8.1 11.6 4 7.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SPX PF03105.19 OAG24316.1 - 6.4e-56 190.9 3.1 1.1e-55 190.2 3.1 1.4 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 OAG24316.1 - 1.4e-06 28.4 13.1 1.8e-06 28.0 11.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG24316.1 - 7.1e-06 25.8 12.3 1.8e-05 24.5 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG24316.1 - 7.7e-06 25.8 7.1 2e-05 24.5 7.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG24316.1 - 8.8e-06 25.5 9.2 1.6e-05 24.7 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG24316.1 - 8.6e-05 22.8 10.7 0.00019 21.7 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG24316.1 - 0.00015 21.6 11.5 0.00084 19.2 11.8 2.1 1 1 1 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 OAG24316.1 - 0.00044 20.4 1.5 0.00079 19.5 1.5 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain zf-C3HC4_2 PF13923.6 OAG24316.1 - 0.00051 19.8 11.5 0.0012 18.6 11.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG24316.1 - 0.0012 18.6 10.3 0.0066 16.3 10.6 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 TFIIA_gamma_N PF02268.16 OAG24316.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF1660 PF07874.11 OAG24316.1 - 0.16 12.4 2.1 0.78 10.3 2.1 2.2 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-RING_4 PF14570.6 OAG24316.1 - 0.54 10.1 12.2 2.8 7.8 12.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cep57_MT_bd PF06657.13 OAG24316.1 - 0.55 10.7 3.1 2.3 8.7 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 zf-Di19 PF05605.12 OAG24316.1 - 7 7.0 8.1 6.7 7.1 0.2 3.0 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2370 PF10176.9 OAG24317.1 - 2.1e-87 292.5 0.0 3.2e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) F-box-like PF12937.7 OAG24319.1 - 2.7e-08 33.6 1.5 2e-07 30.8 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG24319.1 - 2e-06 27.5 1.9 5.2e-06 26.2 0.2 2.5 2 1 0 2 2 2 1 F-box domain HA2 PF04408.23 OAG24321.1 - 2.8e-19 69.4 0.1 2.8e-19 69.4 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG24321.1 - 7.3e-15 55.1 0.0 1.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG24321.1 - 8.7e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG24321.1 - 5.5e-07 29.5 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG24321.1 - 4.5e-06 27.0 0.0 1.3e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG24321.1 - 3.8e-05 24.1 0.1 9.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG24321.1 - 8.3e-05 22.4 0.1 0.00023 21.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG24321.1 - 0.0006 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 OAG24321.1 - 0.0032 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG24321.1 - 0.0033 18.0 0.8 0.02 15.4 0.0 2.5 1 1 1 2 2 2 1 ABC transporter ATPase PF06745.13 OAG24321.1 - 0.013 14.9 0.2 0.05 12.9 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 OAG24321.1 - 0.022 15.1 0.8 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG24321.1 - 0.039 13.9 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase MCC-bdg_PDZ PF10506.9 OAG24321.1 - 0.068 13.2 0.5 0.21 11.6 0.5 1.8 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_11 PF13086.6 OAG24321.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF4110 PF13422.6 OAG24322.1 - 2.6e-32 110.8 0.6 2.6e-32 110.8 0.6 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 OAG24322.1 - 2.1e-28 98.1 8.5 3.7e-09 36.4 0.0 6.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG24322.1 - 2.4e-25 88.0 0.7 7.7e-08 32.2 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAG24322.1 - 6.1e-23 80.6 12.5 1.1e-06 28.8 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG24322.1 - 6.3e-23 80.2 1.9 4.5e-05 23.6 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OAG24322.1 - 9.1e-19 66.8 1.9 1.1e-05 24.9 0.1 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OAG24322.1 - 1e-12 47.5 5.6 0.048 13.7 0.0 6.1 7 1 0 7 7 7 4 Kelch motif DUF4947 PF16305.5 OAG24322.1 - 4.7 7.2 8.1 0.56 10.2 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4947) Tub_N PF16322.5 OAG24322.1 - 8 6.8 27.5 8.2 6.8 17.6 3.3 2 1 0 2 2 2 0 Tubby N-terminal Abhydrolase_1 PF00561.20 OAG24323.1 - 2.3e-17 63.5 0.0 5.2e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG24323.1 - 6.9e-10 38.6 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG24323.1 - 0.0005 19.6 0.0 0.01 15.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG24323.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 OAG24323.1 - 0.057 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FAD_binding_3 PF01494.19 OAG24324.1 - 5e-12 45.7 3.5 2.6e-10 40.1 0.3 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG24324.1 - 2.9e-06 27.4 0.6 1e-05 25.7 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG24324.1 - 0.0001 22.0 1.7 0.0002 21.0 1.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG24324.1 - 0.00011 21.4 0.0 0.00064 18.9 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAG24324.1 - 0.001 19.1 0.3 0.35 10.9 0.4 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG24324.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG24324.1 - 0.0034 17.9 0.2 0.0099 16.4 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG24324.1 - 0.11 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 OAG24324.1 - 0.11 11.7 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Peptidase_C15 PF01470.17 OAG24325.1 - 2.8e-08 34.2 0.0 0.002 18.3 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF2855 PF11017.8 OAG24326.1 - 8.5e-76 255.9 0.1 9.8e-76 255.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Pkinase PF00069.25 OAG24327.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24327.1 - 5e-27 94.8 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG24327.1 - 1.1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG24327.1 - 0.00015 20.6 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG24327.1 - 0.00069 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG24327.1 - 0.0008 19.4 0.6 0.0013 18.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family iPGM_N PF06415.13 OAG24328.1 - 7.6e-77 257.6 0.0 1.3e-76 256.8 0.0 1.4 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 OAG24328.1 - 3.3e-75 252.6 0.1 3.9e-75 252.4 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 OAG24328.1 - 1.4e-05 24.9 0.1 7e-05 22.6 0.0 2.2 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG24328.1 - 2.3e-05 24.0 0.0 0.0018 17.8 0.0 2.9 3 1 1 4 4 4 1 Sulfatase Alk_phosphatase PF00245.20 OAG24328.1 - 0.002 17.1 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.12 OAG24328.1 - 0.036 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Arm-DNA-bind_2 PF12167.8 OAG24328.1 - 0.15 12.0 0.1 27 4.8 0.1 2.4 2 0 0 2 2 2 0 Arm DNA-binding domain DUF4973 PF16343.5 OAG24328.1 - 0.16 12.0 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) Med9 PF07544.13 OAG24329.1 - 6.3e-18 64.6 0.0 9e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Uso1_p115_C PF04871.13 OAG24329.1 - 0.00074 19.9 0.3 0.0013 19.1 0.3 1.4 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Med21 PF11221.8 OAG24329.1 - 0.0035 17.6 6.8 0.0053 17.0 6.8 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 OAG24329.1 - 0.053 13.8 0.3 0.099 12.9 0.3 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain ADIP PF11559.8 OAG24329.1 - 0.069 13.2 0.1 0.092 12.8 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1993 PF09351.10 OAG24329.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Spc24 PF08286.11 OAG24329.1 - 0.23 11.7 0.3 0.36 11.1 0.2 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 AMH_N PF04709.12 OAG24329.1 - 1 8.2 5.3 1.1 8.1 4.5 1.4 1 1 1 2 2 2 0 Anti-Mullerian hormone, N terminal region ETF_QO PF05187.13 OAG24331.1 - 5.5e-49 164.6 1.2 8.8e-49 164.0 1.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 OAG24331.1 - 2e-07 30.5 1.1 0.00046 19.4 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG24331.1 - 4.3e-07 29.9 0.1 0.00041 20.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG24331.1 - 4.8e-06 26.7 0.1 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG24331.1 - 3.7e-05 23.1 0.0 0.00011 21.6 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG24331.1 - 7.4e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG24331.1 - 8.4e-05 21.9 0.1 0.0013 18.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAG24331.1 - 0.00016 22.2 0.2 1.2 9.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG24331.1 - 0.00031 19.6 0.4 0.00052 18.8 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG24331.1 - 0.0012 18.2 0.3 0.0017 17.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG24331.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG24331.1 - 0.0094 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 OAG24331.1 - 0.039 14.5 0.8 0.091 13.4 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 OAG24331.1 - 0.04 13.0 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG24331.1 - 0.043 12.7 0.2 0.23 10.3 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OAG24331.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG24331.1 - 0.15 11.1 0.5 0.22 10.6 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.22 OAG24332.1 - 2.2e-22 78.6 0.0 2.4e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAG24332.1 - 0.29 10.9 0.0 20 4.9 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Ccdc124 PF06244.12 OAG24335.1 - 0.02 15.4 5.1 0.023 15.2 5.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 MHB PF16525.5 OAG24335.1 - 0.045 14.0 0.4 0.071 13.4 0.4 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding Dioxygenase_C PF00775.21 OAG24336.1 - 1.6e-39 135.2 0.0 2.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG24336.1 - 2.7e-32 110.5 0.0 1e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG24336.1 - 0.078 13.3 0.0 0.31 11.4 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Cyt-b5 PF00173.28 OAG24338.1 - 2.8e-12 46.6 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3445 PF11927.8 OAG24339.1 - 6.5e-71 238.5 0.0 8.1e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) GidB PF02527.15 OAG24339.1 - 0.16 11.3 0.2 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Pkinase PF00069.25 OAG24340.1 - 2.8e-47 161.3 0.1 7.8e-47 159.9 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24340.1 - 2e-28 99.4 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG24340.1 - 0.00063 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG24340.1 - 0.0032 17.4 0.6 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG24340.1 - 0.065 12.8 0.4 0.37 10.4 0.4 2.2 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 OAG24340.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Barttin PF15462.6 OAG24340.1 - 2.7 7.7 13.6 0.034 13.9 5.4 2.1 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Zn_clus PF00172.18 OAG24341.1 - 2e-09 37.4 13.4 3.1e-09 36.8 10.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 OAG24341.1 - 3.2e-08 33.6 0.3 6.8e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) F-box-like PF12937.7 OAG24342.1 - 0.0068 16.3 0.2 0.019 14.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like Fasciclin PF02469.22 OAG24343.1 - 6.7e-51 171.8 0.8 7.3e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3203 PF11462.8 OAG24343.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) Fungal_trans PF04082.18 OAG24344.1 - 9.5e-10 37.9 0.1 9e-09 34.7 0.1 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SRCR_2 PF15494.6 OAG24344.1 - 0.2 12.2 0.1 1.3 9.6 0.1 2.2 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain DHquinase_I PF01487.15 OAG24345.1 - 3.3e-25 89.7 0.1 1.2e-24 87.8 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAG24345.1 - 1.4e-18 66.9 0.0 3e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAG24345.1 - 1.8e-12 47.6 0.0 3.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 OAG24345.1 - 9.6e-09 34.9 0.1 2.3e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAG24345.1 - 2.3e-08 34.2 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG24345.1 - 0.0017 18.9 0.1 0.0046 17.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG24345.1 - 0.0017 18.6 0.0 0.0057 16.9 0.0 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AAA_18 PF13238.6 OAG24345.1 - 0.0023 18.5 0.0 0.0062 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG24345.1 - 0.022 15.2 0.3 0.054 13.9 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain ApbA PF02558.16 OAG24345.1 - 0.047 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IstB_IS21 PF01695.17 OAG24345.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAG24345.1 - 0.089 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain PglD_N PF17836.1 OAG24345.1 - 0.11 13.2 0.0 2.2 9.0 0.0 2.7 3 0 0 3 3 3 0 PglD N-terminal domain AAA PF00004.29 OAG24345.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) CEP170_C PF15308.6 OAG24345.1 - 0.3 9.6 3.6 0.53 8.8 3.6 1.3 1 0 0 1 1 1 0 CEP170 C-terminus DASH_Duo1 PF08651.10 OAG24346.1 - 0.26 11.1 2.7 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF3649 PF12365.8 OAG24346.1 - 1.2 8.9 4.7 2.7 7.8 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) DUF812 PF05667.11 OAG24346.1 - 7.7 5.3 9.0 0.1 11.5 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF812) ABC_tran PF00005.27 OAG24347.1 - 0.001 19.6 0.3 0.016 15.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 OAG24347.1 - 0.0058 16.4 0.2 0.013 15.2 0.2 1.7 1 1 1 2 2 2 1 AAA domain IIGP PF05049.13 OAG24347.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 OAG24347.1 - 0.02 15.0 0.6 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Dynamin family OmpH PF03938.14 OAG24347.1 - 0.028 14.8 3.2 0.044 14.1 3.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_29 PF13555.6 OAG24347.1 - 0.03 14.1 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG24347.1 - 0.13 12.8 5.9 4.4 7.8 1.1 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAG24347.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OAG24347.1 - 0.14 12.2 1.0 0.21 11.7 0.2 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG24347.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 OAG24348.1 - 1.1e-07 31.9 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG24348.1 - 9.8e-05 22.5 4.5 0.018 15.1 0.2 2.8 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 OAG24348.1 - 0.00018 20.9 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 OAG24348.1 - 0.0014 19.2 0.2 0.003 18.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 OAG24348.1 - 0.0014 19.2 0.8 0.11 13.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG24348.1 - 0.0041 17.0 0.2 0.0095 15.9 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OAG24348.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin IIGP PF05049.13 OAG24348.1 - 0.079 12.0 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 OAG24348.1 - 0.1 12.3 0.5 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1515 PF07439.11 OAG24348.1 - 0.2 11.7 2.5 0.54 10.3 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Bap31_Bap29_C PF18035.1 OAG24348.1 - 0.24 11.4 5.5 6.3 6.9 0.1 2.2 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_21 PF13304.6 OAG24348.1 - 0.41 10.4 1.1 0.65 9.7 1.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAG24348.1 - 1.1 9.4 4.7 0.81 9.8 1.4 2.4 2 1 0 2 2 2 0 AAA domain Macoilin PF09726.9 OAG24349.1 - 8 4.9 11.3 9.6 4.6 11.3 1.1 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 OAG24349.1 - 8.3 6.2 15.2 10 5.9 15.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MerR_2 PF13591.6 OAG24350.1 - 0.17 11.8 0.1 0.85 9.5 0.1 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF3112 PF11309.8 OAG24351.1 - 5.1e-08 32.6 2.3 5.1e-08 32.6 2.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DJ-1_PfpI PF01965.24 OAG24352.1 - 2.7e-12 46.8 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Vps35 PF03635.17 OAG24353.1 - 0 1022.7 6.7 0 1022.5 6.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pro_3_hydrox_C PF05373.11 OAG24353.1 - 0.04 14.0 0.3 8.1 6.6 0.0 2.9 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal DUF2868 PF11067.8 OAG24353.1 - 0.071 12.6 2.9 0.17 11.4 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Dicty_REP PF05086.12 OAG24353.1 - 0.089 10.8 1.4 0.15 10.0 1.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPX PF03105.19 OAG24354.1 - 1 9.2 6.2 1.1 9.1 6.2 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 OAG24354.1 - 2.4 7.2 14.5 2.8 7.0 14.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FixQ PF05545.11 OAG24355.1 - 0.0074 16.2 0.2 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ TMEM51 PF15345.6 OAG24355.1 - 0.0078 16.1 0.1 0.0088 15.9 0.1 1.3 1 1 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 OAG24355.1 - 0.0087 15.5 0.3 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OAG24355.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FIVAR PF07554.13 OAG24355.1 - 0.024 15.4 1.9 0.024 15.4 1.9 1.8 2 0 0 2 2 2 0 FIVAR domain LapA_dom PF06305.11 OAG24355.1 - 0.066 13.0 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Trp_oprn_chp PF09534.10 OAG24355.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Adeno_E3_CR2 PF02439.15 OAG24355.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cation_efflux PF01545.21 OAG24355.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family HpcH_HpaI PF03328.14 OAG24356.1 - 1.2e-25 89.9 0.0 1.7e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family G10 PF01125.17 OAG24356.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 G10 protein PK PF00224.21 OAG24356.1 - 0.036 12.9 0.1 0.073 11.9 0.1 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Syndecan PF01034.20 OAG24357.1 - 0.0031 17.4 0.5 0.0048 16.8 0.5 1.3 1 0 0 1 1 1 1 Syndecan domain TFR_dimer PF04253.15 OAG24358.1 - 1.7e-30 105.6 0.0 3.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG24358.1 - 4.3e-15 55.9 0.0 7.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG24358.1 - 1e-11 44.7 0.0 2.4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PA domain adh_short_C2 PF13561.6 OAG24359.1 - 7.5e-48 163.1 7.7 5.5e-45 153.7 7.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24359.1 - 1.3e-44 152.0 5.4 1.6e-44 151.7 5.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24359.1 - 2.2e-14 53.8 1.1 3.3e-14 53.2 1.1 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OAG24359.1 - 0.011 15.8 0.5 0.019 15.1 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 OAG24359.1 - 0.013 15.3 1.1 0.023 14.6 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG24359.1 - 0.045 13.1 0.4 0.076 12.4 0.4 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG24359.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AMP-binding PF00501.28 OAG24360.1 - 1.8e-25 89.4 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG24360.1 - 0.037 15.0 0.2 0.094 13.7 0.2 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Macro PF01661.21 OAG24360.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Macro domain MFS_1 PF07690.16 OAG24361.1 - 3.2e-09 36.2 29.8 3.2e-09 36.2 29.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG24361.1 - 5.7e-07 29.4 2.9 5.7e-07 29.4 2.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 OAG24361.1 - 9.5e-06 24.7 7.0 9.5e-06 24.7 7.0 3.0 3 1 0 4 4 4 1 Sugar (and other) transporter PUCC PF03209.15 OAG24361.1 - 0.09 11.8 7.5 0.016 14.2 3.5 1.8 2 0 0 2 2 2 0 PUCC protein ATPase_gene1 PF09527.10 OAG24361.1 - 4.7 7.4 14.7 4.8 7.4 2.2 3.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DAO PF01266.24 OAG24362.1 - 9.1e-43 147.2 0.0 1.1e-42 147.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG24362.1 - 7e-05 22.2 0.0 0.24 10.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG24362.1 - 0.024 14.6 0.4 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Epimerase PF01370.21 OAG24362.1 - 0.035 13.6 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GIDA PF01134.22 OAG24362.1 - 0.056 12.5 0.0 0.92 8.5 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 OAG24362.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 OAG24362.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SnoaL PF07366.12 OAG24364.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG24364.1 - 0.0053 17.4 0.0 0.025 15.2 0.0 2.0 1 1 1 2 2 2 1 SnoaL-like domain DUF1257 PF06868.11 OAG24364.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DLH PF01738.18 OAG24364.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Elf1 PF05129.13 OAG24365.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ribosomal_S13 PF00416.22 OAG24366.1 - 2.6e-54 183.0 1.9 3e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 OAG24366.1 - 0.015 14.1 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 OAG24366.1 - 0.074 13.5 0.2 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SBDS_C PF09377.10 OAG24368.1 - 1.8e-40 137.6 1.0 4.2e-40 136.4 0.1 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 OAG24368.1 - 2.3e-33 114.1 0.7 4.2e-33 113.3 0.7 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.22 OAG24369.1 - 8.4e-130 433.9 2.2 1e-129 433.6 2.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 OAG24369.1 - 1.1e-17 64.7 1.3 2.7e-17 63.5 1.3 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Fungal_TACC PF12709.7 OAG24370.1 - 3.3 8.2 8.9 0.93 10.0 2.0 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Sugar_tr PF00083.24 OAG24371.1 - 4.8e-124 414.7 22.2 1.3e-123 413.3 22.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG24371.1 - 6.6e-33 114.1 62.7 6.4e-26 91.1 35.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG24371.1 - 8.2e-05 21.2 12.2 0.0053 15.2 6.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Dexa_ind PF15198.6 OAG24371.1 - 4.5 7.4 5.2 49 4.1 0.0 3.6 4 0 0 4 4 4 0 Dexamethasone-induced AnmK PF03702.14 OAG24372.1 - 8.5e-34 117.2 0.0 1.1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Fungal_trans_2 PF11951.8 OAG24373.1 - 4.8e-12 45.4 0.3 6.5e-08 31.8 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24373.1 - 3.9e-06 26.9 12.9 1.3e-05 25.2 12.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Img2 PF05046.14 OAG24375.1 - 2.1e-27 95.2 0.2 2.8e-27 94.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 OAG24376.1 - 8.2e-43 146.0 6.1 3.2e-42 144.1 5.7 2.2 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAG24376.1 - 6.2e-16 58.8 0.1 2.2e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.9 OAG24376.1 - 0.005 16.5 3.1 0.021 14.4 0.5 2.4 2 0 0 2 2 2 1 DDRGK domain RPN7 PF10602.9 OAG24376.1 - 0.031 14.0 0.2 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Frag1 PF10277.9 OAG24377.1 - 2e-37 128.8 6.1 2e-37 128.8 6.1 2.9 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 OAG24377.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 OAG24378.1 - 1.8e-24 85.6 4.1 1.9e-24 85.5 1.9 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OAG24378.1 - 4.7e-07 30.1 3.2 0.61 11.1 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat RF-1 PF00472.20 OAG24379.1 - 1.6e-19 70.0 1.8 2.2e-19 69.5 1.8 1.2 1 0 0 1 1 1 1 RF-1 domain Pro_Al_protease PF02983.14 OAG24379.1 - 0.021 14.9 0.7 0.081 13.0 0.0 2.3 2 0 0 2 2 2 0 Alpha-lytic protease prodomain RRM_1 PF00076.22 OAG24380.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG24380.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 OAG24380.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.13 OAG24381.1 - 3.9e-13 49.4 0.1 3e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein BAR_3 PF16746.5 OAG24381.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Acyl-CoA_dh_1 PF00441.24 OAG24382.1 - 1.1e-34 119.9 0.9 1.7e-34 119.2 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 OAG24382.1 - 3.9e-20 71.8 0.0 1.6e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 OAG24382.1 - 1.1e-15 57.5 0.3 2.1e-15 56.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG24382.1 - 2.4e-08 34.3 0.0 4.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG24382.1 - 2.8e-08 34.4 0.1 6.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain ubiquitin PF00240.23 OAG24383.1 - 4.1e-12 45.7 0.0 8.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 OAG24383.1 - 9e-11 41.8 5.8 9e-11 41.8 5.8 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Sde2_N_Ubi PF13019.6 OAG24383.1 - 0.00025 20.9 0.8 0.00042 20.2 0.8 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Rad60-SLD PF11976.8 OAG24383.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG24383.1 - 0.016 15.8 0.1 0.02 15.5 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain MFS_1 PF07690.16 OAG24385.1 - 4.2e-32 111.4 20.8 6.9e-25 87.7 22.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2013 PF09431.10 OAG24386.1 - 3.9e-50 169.6 0.7 8.9e-50 168.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Clathrin PF00637.20 OAG24387.1 - 1.3e-17 64.0 0.2 3e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_UBOX PF13445.6 OAG24387.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OAG24387.1 - 0.053 13.3 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 OAG24387.1 - 0.07 13.1 0.1 0.07 13.1 0.1 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 OAG24387.1 - 0.098 13.0 0.2 0.23 11.8 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG24387.1 - 0.13 12.1 0.2 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OAG24387.1 - 0.17 12.8 1.1 1e+02 4.0 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF155 PF02582.14 OAG24388.1 - 4.2e-48 163.8 0.0 6.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 OAG24388.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 OAG24388.1 - 0.043 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) NmrA PF05368.13 OAG24389.1 - 7.7e-16 58.4 0.0 9.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG24389.1 - 9.7e-15 54.7 0.1 2e-14 53.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG24389.1 - 3.2e-13 50.0 0.0 4.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG24389.1 - 8e-12 44.7 0.1 1.7e-11 43.7 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG24389.1 - 8.2e-09 35.3 0.2 5.3e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG24389.1 - 1.7e-05 24.1 0.7 0.0038 16.4 0.3 3.1 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 OAG24389.1 - 2.1e-05 23.8 0.0 0.0014 17.8 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OAG24389.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24389.1 - 0.01 15.8 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.6 OAG24389.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAG24389.1 - 0.041 13.0 0.0 0.084 12.0 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_synthase PF02540.17 OAG24389.1 - 0.081 12.0 0.1 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 NAD synthase ApbA PF02558.16 OAG24389.1 - 0.19 11.4 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PCI PF01399.27 OAG24390.1 - 1.5e-07 31.9 0.0 4.2e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 OAG24390.1 - 0.00023 20.7 1.0 0.00052 19.6 1.0 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix ANAPC5 PF12862.7 OAG24390.1 - 0.029 14.4 2.0 0.17 12.0 0.5 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Gaa1 PF04114.14 OAG24391.1 - 4.7e-166 553.7 2.9 8e-166 552.9 2.9 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Hid1 PF12722.7 OAG24391.1 - 0.05 11.7 0.7 0.074 11.2 0.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 OAG24391.1 - 0.27 10.0 2.5 0.44 9.3 2.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MSA_2 PF00985.17 OAG24391.1 - 5.4 7.3 10.1 8.7 6.7 10.1 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Rhomboid PF01694.22 OAG24392.1 - 1.5e-13 51.1 7.1 1.5e-13 51.1 7.1 1.4 2 0 0 2 2 2 1 Rhomboid family HisKA PF00512.25 OAG24394.1 - 0.15 12.1 1.8 2.9 8.0 0.3 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Glyco_hydro_28 PF00295.17 OAG24395.1 - 1.7e-106 356.0 21.8 2e-106 355.8 21.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_35 PF01301.19 OAG24396.1 - 7e-91 305.1 2.3 1.2e-90 304.3 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG24396.1 - 2.4e-58 195.6 4.9 3.4e-34 117.8 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAG24396.1 - 1.2e-46 158.8 6.5 1.2e-46 158.8 6.5 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAG24396.1 - 1.2e-25 88.9 0.1 1.2e-24 85.7 0.1 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 OAG24396.1 - 0.011 15.1 0.1 0.029 13.8 0.1 1.7 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Acetyltransf_1 PF00583.25 OAG24397.1 - 7.4e-12 45.5 0.0 1.2e-11 44.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG24397.1 - 1.4e-09 37.9 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG24397.1 - 1.9e-07 31.4 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG24397.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OAG24397.1 - 0.0052 16.9 0.0 0.0078 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG24397.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_8 PF05148.15 OAG24398.1 - 1.4e-47 162.4 0.0 6e-25 88.4 0.0 3.4 4 0 0 4 4 4 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OAG24398.1 - 6.6e-06 26.7 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG24398.1 - 2.2e-05 25.1 0.0 0.00042 21.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG24398.1 - 0.0015 18.4 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG24398.1 - 0.11 13.2 0.2 1.1 10.0 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain TPR_MLP1_2 PF07926.12 OAG24399.1 - 0.0073 16.4 6.7 0.0073 16.4 6.7 3.0 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein YabA PF06156.13 OAG24399.1 - 0.029 15.0 20.0 0.063 13.9 3.8 4.0 3 2 1 4 4 4 0 Initiation control protein YabA ZapB PF06005.12 OAG24399.1 - 0.071 13.6 17.7 0.31 11.5 6.3 3.4 2 1 0 2 2 2 0 Cell division protein ZapB Bacillus_HBL PF05791.11 OAG24399.1 - 0.18 11.6 13.6 2.8 7.8 2.5 4.0 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 OAG24399.1 - 0.32 9.8 23.1 0.58 9.0 8.3 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 OAG24399.1 - 0.43 10.6 22.6 2.7 8.0 6.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 OAG24399.1 - 0.57 10.5 9.2 5.7 7.3 0.5 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family UPF0242 PF06785.11 OAG24399.1 - 0.86 9.7 25.7 0.46 10.6 11.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OAG24399.1 - 1.2 9.6 23.8 0.45 11.0 10.1 2.8 2 1 1 3 3 2 0 Apg6 coiled-coil region GIT_CC PF16559.5 OAG24399.1 - 1.7 8.6 9.1 2 8.3 0.5 3.5 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 OAG24399.1 - 2 8.9 15.8 6.5 7.2 3.8 2.8 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Lebercilin PF15619.6 OAG24399.1 - 2 8.0 23.4 0.2 11.3 4.8 3.2 2 1 0 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease DHR10 PF18595.1 OAG24399.1 - 2.3 8.3 20.7 3.8 7.6 7.8 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 OAG24399.1 - 2.8 8.0 11.1 8.2 6.5 0.9 3.3 1 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 OAG24399.1 - 3.3 6.7 18.7 0.88 8.6 7.5 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KLRAQ PF10205.9 OAG24399.1 - 3.8 7.8 10.7 1 9.6 1.9 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Mito_fiss_reg PF05308.11 OAG24399.1 - 4.3 7.3 8.7 13 5.8 6.9 2.4 1 1 0 1 1 1 0 Mitochondrial fission regulator FlaC_arch PF05377.11 OAG24399.1 - 4.5 7.7 13.0 0.71 10.3 0.2 5.0 4 2 3 7 7 6 0 Flagella accessory protein C (FlaC) Sec2p PF06428.11 OAG24399.1 - 5.2 7.1 13.5 0.26 11.3 3.6 3.2 2 2 0 2 2 2 0 GDP/GTP exchange factor Sec2p kleA_kleC PF17383.2 OAG24399.1 - 6.9 7.1 7.8 0.4 11.1 1.1 2.4 3 1 0 3 3 2 0 Uncharacterized KorC regulated protein A OmpH PF03938.14 OAG24399.1 - 7.6 6.9 27.5 4.2 7.7 14.1 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 OAG24399.1 - 8.6 7.1 15.0 0.72 10.5 3.5 3.3 3 1 1 4 4 3 0 SlyX DUF724 PF05266.14 OAG24399.1 - 8.7 6.1 14.5 9.8 5.9 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sugar_tr PF00083.24 OAG24401.1 - 1.5e-85 287.8 16.2 1.8e-85 287.5 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG24401.1 - 9.1e-30 103.8 25.7 7.3e-24 84.4 11.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG24401.1 - 0.0016 16.9 0.9 0.0016 16.9 0.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1304 PF06993.12 OAG24401.1 - 0.0073 16.3 1.3 0.0073 16.3 1.3 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF1304) DUF2839 PF10999.8 OAG24401.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) BLACT_WH PF17778.1 OAG24402.1 - 5.9e-16 58.2 0.0 1.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 OAG24402.1 - 3.2e-15 56.7 3.4 1.6e-13 51.1 3.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG24402.1 - 1.7e-06 27.7 1.0 3.1e-06 26.9 1.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain N6-adenineMlase PF10237.9 OAG24403.1 - 1.4e-47 161.5 0.1 1.7e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 OAG24403.1 - 0.0006 19.5 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 OAG24403.1 - 0.0099 15.6 0.0 0.029 14.1 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 HIT PF01230.23 OAG24404.1 - 5.5e-23 81.6 0.7 7.8e-23 81.1 0.7 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG24404.1 - 6.5e-13 49.2 0.2 8.9e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAG24404.1 - 4.2e-05 23.4 0.1 5.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 OAG24404.1 - 0.0086 16.5 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 ECH_1 PF00378.20 OAG24405.1 - 4e-39 134.4 0.0 9.7e-39 133.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG24405.1 - 4.9e-26 92.0 0.0 6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RPAP1_C PF08620.10 OAG24406.1 - 7.1e-27 93.3 0.0 1.5e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 OAG24406.1 - 3.4e-18 65.1 6.4 7.2e-18 64.1 6.4 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal UCH PF00443.29 OAG24407.1 - 1.2e-34 120.0 0.0 2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 OAG24407.1 - 1.8e-33 114.2 0.5 3.8e-18 65.1 0.1 4.0 4 0 0 4 4 4 3 A repeated domain in UCH-protein UCH_1 PF13423.6 OAG24407.1 - 3.6e-05 23.5 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.19 OAG24408.1 - 0.0014 19.0 3.9 0.0031 17.9 3.7 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.12 OAG24409.1 - 1.6e-31 108.5 0.0 2.7e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OAG24409.1 - 2.9e-10 40.6 2.7 7.8e-10 39.2 0.3 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain DUF3914 PF13053.6 OAG24409.1 - 0.084 13.2 1.0 13 6.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) SPATA3 PF15662.5 OAG24409.1 - 0.18 12.4 12.5 0.084 13.5 9.9 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family WD40 PF00400.32 OAG24410.1 - 1e-48 162.2 17.3 5.8e-09 36.4 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OAG24410.1 - 5.4e-39 133.4 0.5 7.8e-39 132.9 0.5 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OAG24410.1 - 1.9e-09 37.7 0.1 0.017 15.4 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAG24410.1 - 9.7e-07 28.5 0.1 2.1e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 OAG24410.1 - 7.2e-06 24.9 1.1 0.019 13.6 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.12 OAG24410.1 - 0.015 13.4 0.0 0.025 12.6 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DUF2027 PF09640.10 OAG24410.1 - 0.076 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) RAB3GAP2_N PF14655.6 OAG24410.1 - 0.2 10.9 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med11 PF10280.9 OAG24411.1 - 2.4e-14 54.0 0.0 4.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Mediator complex protein MscS_TM PF12794.7 OAG24411.1 - 0.42 9.4 0.4 0.64 8.8 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 S-methyl_trans PF02574.16 OAG24412.1 - 1.2e-73 248.2 0.0 1.4e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SUI1 PF01253.22 OAG24414.1 - 6.4e-28 97.1 5.0 7.7e-28 96.8 4.3 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 OAG24414.1 - 0.062 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DNA_ligase_A_M PF01068.21 OAG24415.1 - 1.5e-50 171.7 0.0 9.6e-48 162.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG24415.1 - 6.4e-36 124.3 0.1 2e-35 122.7 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAG24415.1 - 1e-19 70.9 0.4 7.5e-18 65.0 0.0 3.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OAG24415.1 - 0.00041 20.7 0.0 0.00083 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Med14 PF08638.11 OAG24417.1 - 1.9e-53 180.7 0.3 1.9e-53 180.7 0.3 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 DUF1387 PF07139.11 OAG24417.1 - 7.8 6.1 12.2 14 5.3 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TERB2 PF15101.6 OAG24417.1 - 8 6.5 14.0 16 5.5 14.0 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 OAG24417.1 - 9.4 5.5 12.1 20 4.4 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG22 PF11700.8 OAG24418.1 - 8.6e-199 661.1 8.5 1.1e-198 660.8 8.5 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG24418.1 - 2.9e-06 26.5 23.8 2.9e-06 26.5 23.8 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily UPF0182 PF03699.13 OAG24418.1 - 0.088 10.9 4.8 0.12 10.5 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Pex24p PF06398.11 OAG24418.1 - 1.7 7.5 4.2 2.7 6.9 3.2 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin TBPIP PF07106.13 OAG24419.1 - 9e-19 67.2 0.5 6.8e-18 64.4 0.1 2.1 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 OAG24419.1 - 5.3e-05 23.5 0.2 0.00011 22.5 0.2 1.6 1 0 0 1 1 1 1 Penicillinase repressor DUF3829 PF12889.7 OAG24419.1 - 0.0073 15.8 1.2 0.01 15.4 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) DUF2487 PF10673.9 OAG24419.1 - 0.02 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) DUF3490 PF11995.8 OAG24419.1 - 1.7 8.5 6.2 0.72 9.7 3.6 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3490) AAA PF00004.29 OAG24420.1 - 3.7e-38 131.0 0.0 7e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAG24420.1 - 8e-09 35.4 0.5 1.1e-07 31.7 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 OAG24420.1 - 2.2e-07 30.6 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OAG24420.1 - 1.6e-05 25.2 0.2 0.00096 19.4 0.2 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG24420.1 - 3.2e-05 23.7 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAG24420.1 - 0.0004 20.6 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG24420.1 - 0.00064 19.7 0.0 0.002 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG24420.1 - 0.00068 18.9 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAG24420.1 - 0.0015 19.0 3.1 0.0035 17.7 0.2 3.0 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG24420.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAG24420.1 - 0.0048 16.3 0.1 0.0098 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OAG24420.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG24420.1 - 0.018 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG24420.1 - 0.02 15.4 0.1 0.061 13.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 OAG24420.1 - 0.021 15.0 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.13 OAG24420.1 - 0.031 14.2 0.0 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain AAA_25 PF13481.6 OAG24420.1 - 0.043 13.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG24420.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG24420.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OAG24420.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAG24420.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NEMO PF11577.8 OAG24420.1 - 0.22 11.5 2.5 0.6 10.2 2.5 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO AAA_28 PF13521.6 OAG24420.1 - 0.32 11.2 1.4 0.92 9.7 0.1 2.4 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 OAG24421.1 - 1.6e-63 210.7 1.4 7.6e-22 77.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2 PF00152.20 OAG24421.1 - 1.3e-62 211.7 0.0 2.1e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG24421.1 - 1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.9 OAG24422.1 - 9.6e-15 55.2 0.0 1.4e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) COX6B PF02297.17 OAG24423.1 - 2.5e-23 82.1 7.3 3e-23 81.8 7.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAG24423.1 - 0.1 12.9 3.1 0.97 9.8 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 OAG24424.1 - 1.9e-59 199.9 8.9 2.2e-59 199.8 8.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Saf_2TM PF18303.1 OAG24424.1 - 0.27 10.8 2.3 0.42 10.2 2.3 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain TPR_19 PF14559.6 OAG24425.1 - 8.4e-08 32.6 0.7 0.021 15.4 0.1 5.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG24425.1 - 4.2e-07 29.5 1.7 0.019 14.8 0.2 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG24425.1 - 7.3e-06 25.7 6.2 0.12 12.5 0.3 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG24425.1 - 0.00012 21.7 1.7 0.15 11.8 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 OAG24425.1 - 0.0048 17.6 14.6 15 6.8 0.0 8.4 9 2 1 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG24425.1 - 0.0076 16.4 2.1 9.3 6.7 0.1 5.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG24425.1 - 0.06 13.4 3.1 3.5e+02 1.6 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat HTH_16 PF12645.7 OAG24425.1 - 0.082 13.0 0.0 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Lambda_Kil PF06301.11 OAG24425.1 - 0.17 11.6 0.2 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein TPR_16 PF13432.6 OAG24425.1 - 1.3 9.7 6.7 5.2 7.8 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SDA1 PF05285.12 OAG24425.1 - 4.7 6.5 11.4 0.15 11.5 5.1 1.6 2 0 0 2 2 2 0 SDA1 VacA PF02691.15 OAG24426.1 - 0.097 10.5 0.0 0.12 10.2 0.0 1.0 1 0 0 1 1 1 0 Vacuolating cyotoxin HSL_N PF06350.12 OAG24427.1 - 0.013 14.4 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus ANAPC2 PF08672.11 OAG24428.1 - 8.2e-15 55.1 0.6 2.2e-14 53.7 0.1 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 OAG24428.1 - 5.7e-14 51.6 0.0 1.9e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Cullin family DUF5071 PF16804.5 OAG24428.1 - 0.39 11.0 2.3 18 5.6 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) SMC_N PF02463.19 OAG24430.1 - 1.5e-27 96.4 0.5 3.6e-27 95.2 0.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG24430.1 - 7.3e-15 56.0 11.1 7.3e-15 56.0 11.1 5.2 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 OAG24430.1 - 1.1e-07 31.9 14.8 1.1e-07 31.9 14.8 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAG24430.1 - 6.7e-06 26.1 3.0 0.0029 17.4 0.2 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG24430.1 - 4.1e-05 23.2 0.0 9.4e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Peptidase_M35 PF02102.15 OAG24430.1 - 0.0087 15.0 1.2 0.02 13.8 1.2 1.5 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family ABC_tran PF00005.27 OAG24430.1 - 0.12 12.9 0.1 0.12 12.9 0.1 5.3 3 2 0 3 3 3 0 ABC transporter DUF5075 PF16825.5 OAG24430.1 - 0.21 11.3 2.3 13 5.5 0.9 3.2 3 0 0 3 3 3 0 IGP family C-type lectin domain Sel1 PF08238.12 OAG24431.1 - 1.1e-19 70.4 23.9 4.7e-05 23.9 0.0 6.9 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 OAG24431.1 - 3 7.8 8.9 5.6 7.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 OAG24432.1 - 5.7e-73 243.9 0.1 7.3e-73 243.6 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 OAG24432.1 - 1.1 7.4 21.1 1.4 7.0 21.1 1.0 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.18 OAG24433.1 - 6.6e-13 48.3 0.3 9.7e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24433.1 - 1.9e-06 27.9 13.4 3.8e-06 26.9 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec7 PF01369.20 OAG24434.1 - 7.2e-25 87.7 0.1 1.7e-24 86.5 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 OAG24434.1 - 1.5e-17 64.1 0.0 7.1e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Peptidase_C14 PF00656.22 OAG24435.1 - 2.2e-61 208.0 0.0 2.7e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain AMMECR1 PF01871.17 OAG24436.1 - 6.5e-50 169.0 0.0 8.5e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Ribosomal_L29e PF01779.17 OAG24437.1 - 5.2e-21 74.7 13.2 9.9e-21 73.8 13.2 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family MFS_1 PF07690.16 OAG24438.1 - 3.7e-35 121.5 31.5 5.7e-35 120.9 30.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 OAG24438.1 - 0.005 17.0 0.6 0.005 17.0 0.6 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF2530) Mon1 PF03164.14 OAG24440.1 - 2.5e-156 520.8 0.0 3e-156 520.6 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF2406 PF10295.9 OAG24440.1 - 0.27 11.9 1.5 0.91 10.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) Epimerase PF01370.21 OAG24441.1 - 3.5e-07 29.9 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG24441.1 - 7.9e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG24441.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG24441.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 OAG24441.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG24441.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mrx7 PF10906.8 OAG24442.1 - 1.2e-07 31.8 0.1 2.4e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 OAG24444.1 - 2.9e-57 194.0 0.0 3.7e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAG24444.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Zn_clus PF00172.18 OAG24447.1 - 2.3e-08 34.0 13.5 3.4e-08 33.5 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4132 PF13569.6 OAG24447.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Aldose_epim PF01263.20 OAG24448.1 - 1.8e-61 208.1 0.1 2.3e-61 207.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase JAB PF01398.21 OAG24449.1 - 2e-14 53.6 0.0 3.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 OAG24449.1 - 1.7e-07 31.4 0.2 3.1e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 OAG24449.1 - 0.0001 22.1 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1096 PF06493.11 OAG24449.1 - 0.12 12.8 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) Pkr1 PF08636.10 OAG24450.1 - 3.5e-31 107.2 7.8 4.6e-31 106.8 7.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Trypan_PARP PF05887.11 OAG24450.1 - 5.2e-05 23.2 1.6 7.7e-05 22.7 1.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) adh_short PF00106.25 OAG24451.1 - 1.5e-16 60.4 0.0 2.7e-07 30.3 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24451.1 - 1.8e-07 31.0 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Lgl_C PF08596.10 OAG24455.1 - 1.1e-121 406.3 0.0 2e-121 405.4 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 OAG24455.1 - 2.1e-07 31.5 0.2 0.0049 17.7 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG24455.1 - 1.3e-06 28.6 0.0 0.039 14.3 0.0 5.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3896 PF13035.6 OAG24457.1 - 0.055 13.6 4.5 0.28 11.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) SMC_Nse1 PF07574.13 OAG24457.1 - 4.4 7.2 10.8 0.36 10.7 5.8 1.7 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex SecD-TM1 PF13721.6 OAG24457.1 - 8.9 6.8 7.3 9.2 6.8 3.9 2.5 1 1 1 2 2 2 0 SecD export protein N-terminal TM region RNA_polI_A34 PF08208.11 OAG24459.1 - 3.3e-47 161.2 8.2 3.3e-47 161.2 8.2 3.4 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 OAG24460.1 - 1.1e-12 48.1 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 OAG24460.1 - 0.0025 17.3 0.1 0.021 14.3 0.0 2.3 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAG24460.1 - 0.02 15.0 0.4 0.069 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAG24460.1 - 0.034 14.2 0.0 0.21 11.6 0.0 2.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG24460.1 - 0.072 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain P22_Tail-4 PF11650.8 OAG24460.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 P22 tail accessory factor Complex1_LYR PF05347.15 OAG24461.1 - 2.1e-07 30.9 1.5 3e-07 30.4 1.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 OAG24462.1 - 8.3e-79 264.3 0.1 1.2e-78 263.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG24462.1 - 3e-19 68.6 3.4 6e-19 67.7 3.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 OAG24462.1 - 0.00047 20.8 0.6 1 10.1 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 OAG24462.1 - 0.00063 19.5 0.5 0.21 11.5 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 OAG24462.1 - 0.035 14.0 0.6 0.076 12.9 0.6 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 OAG24462.1 - 0.042 13.8 1.8 0.89 9.5 0.0 2.8 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Presenilin PF01080.17 OAG24462.1 - 0.13 11.0 10.3 0.19 10.4 10.3 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 OAG24462.1 - 0.5 9.5 8.5 0.6 9.2 8.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM76 PF16046.5 OAG24462.1 - 0.95 8.8 10.9 22 4.3 9.4 2.1 2 0 0 2 2 2 0 FAM76 protein LAP1C PF05609.12 OAG24462.1 - 2.5 7.1 10.2 3.5 6.6 10.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 OAG24462.1 - 2.6 6.8 10.5 3.6 6.3 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 OAG24462.1 - 6.3 5.5 10.6 8.9 5.0 10.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 OAG24462.1 - 7.1 6.4 8.9 24 4.7 8.9 1.8 1 1 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 OAG24462.1 - 9.1 4.4 10.8 12 4.0 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Histone_H2A_C PF16211.5 OAG24463.1 - 2.8e-21 74.9 2.6 5e-21 74.1 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAG24463.1 - 6.9e-17 62.0 0.0 9.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG24463.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG24464.1 - 4e-23 82.2 0.4 4.9e-23 81.9 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG24464.1 - 7.3e-05 23.0 1.0 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAG24464.1 - 0.00026 21.4 0.0 0.00044 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 OAG24464.1 - 0.028 15.4 0.4 0.039 15.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 OAG24464.1 - 0.059 13.0 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.19 OAG24465.1 - 7.8e-99 330.5 0.0 9.6e-99 330.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 OAG24467.1 - 5.7e-14 51.8 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 OAG24467.1 - 1.7e-11 43.8 0.4 1.8e-10 40.5 0.3 2.7 2 0 0 2 2 2 1 G-patch domain Chromo PF00385.24 OAG24467.1 - 0.00041 20.2 0.1 0.00041 20.2 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.7 OAG24467.1 - 0.025 14.6 1.2 0.19 11.9 0.7 2.9 2 1 0 2 2 2 0 G-patch domain DUF4136 PF13590.6 OAG24467.1 - 0.027 15.0 0.0 0.09 13.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) CDC45 PF02724.14 OAG24467.1 - 0.13 10.6 7.3 0.23 9.7 7.3 1.5 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG24467.1 - 0.19 9.8 13.0 0.3 9.1 13.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OAG24467.1 - 0.68 9.9 6.7 1.9 8.5 6.7 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Oxysterol_BP PF01237.18 OAG24468.1 - 9.9e-53 179.3 0.0 4.1e-50 170.7 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C39_2 PF13529.6 OAG24468.1 - 0.015 15.9 0.0 4.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_C2 PF00648.21 OAG24469.1 - 4e-26 91.7 0.0 9.1e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAG24469.1 - 1.8e-07 31.5 0.0 4.7e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 OAG24469.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 OAG24470.1 - 1.3e-53 178.9 0.4 1.9e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IncD PF17628.2 OAG24470.1 - 0.078 12.8 1.5 0.28 11.0 0.0 2.4 3 0 0 3 3 3 0 Inclusion membrane protein D Lactamase_B PF00753.27 OAG24471.1 - 2.9e-06 27.4 0.1 4.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG24471.1 - 0.00072 19.1 0.1 0.0024 17.4 0.0 1.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain DUF5007 PF16398.5 OAG24471.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) NAD_binding_6 PF08030.12 OAG24472.1 - 6.9e-32 110.7 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG24472.1 - 1.8e-20 73.0 0.1 4.7e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 OAG24472.1 - 1.9e-17 63.5 10.9 1.9e-17 63.5 10.9 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 OAG24472.1 - 0.035 14.4 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain adh_short_C2 PF13561.6 OAG24473.1 - 8.2e-58 195.7 1.0 9.4e-58 195.5 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24473.1 - 4.8e-46 156.7 0.3 6.2e-46 156.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24473.1 - 8.8e-15 55.1 0.3 1.3e-14 54.5 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG24473.1 - 2.9e-05 23.6 0.1 0.00012 21.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 OAG24473.1 - 0.0035 17.8 0.1 0.75 10.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.19 OAG24473.1 - 0.01 15.2 0.0 0.024 13.9 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain bPH_2 PF03703.14 OAG24473.1 - 0.023 14.9 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial PH domain Glyco_transf_4 PF13439.6 OAG24473.1 - 0.023 14.7 0.0 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 NmrA PF05368.13 OAG24473.1 - 0.032 13.8 0.1 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family DFP PF04127.15 OAG24473.1 - 0.062 13.1 1.6 0.29 11.0 0.2 2.3 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Pyr_redox PF00070.27 OAG24473.1 - 0.12 12.9 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EMG1 PF03587.14 OAG24475.1 - 2e-76 256.0 0.0 2.3e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HAD_SAK_1 PF10307.9 OAG24477.1 - 1.4e-75 253.5 0.0 2.2e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins zf-RING_2 PF13639.6 OAG24478.1 - 1.6e-10 41.1 5.7 2.6e-10 40.5 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG24478.1 - 3.3e-08 33.7 1.8 6.9e-08 32.7 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAG24478.1 - 7.7e-08 32.1 2.6 1.1e-07 31.6 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG24478.1 - 4.8e-06 26.3 4.3 7.3e-06 25.8 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG24478.1 - 7.9e-05 22.4 3.6 0.00012 21.8 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG24478.1 - 8.4e-05 22.3 5.3 0.00013 21.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG24478.1 - 0.0063 16.5 1.6 0.015 15.3 1.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAG24478.1 - 0.048 13.4 2.0 0.089 12.6 2.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 OAG24478.1 - 0.089 12.8 3.5 0.16 12.0 3.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CTU2 PF10288.9 OAG24478.1 - 0.1 12.9 1.5 4.6 7.5 1.5 2.4 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-Nse PF11789.8 OAG24478.1 - 0.44 10.4 1.9 0.78 9.6 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 OAG24478.1 - 0.48 10.1 3.2 0.85 9.3 3.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Peptidase_S41 PF03572.18 OAG24479.1 - 5.5e-07 29.3 0.0 1.9e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_12 PF01670.16 OAG24480.1 - 6.7e-63 212.5 11.0 8.1e-63 212.3 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF4430 PF14478.6 OAG24480.1 - 0.045 14.4 2.5 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) Glyco_hydro_61 PF03443.14 OAG24481.1 - 3.5e-49 167.5 0.3 3.5e-49 167.5 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG24481.1 - 5.9e-14 51.7 11.6 1.4e-13 50.5 11.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mpv17_PMP22 PF04117.12 OAG24483.1 - 5.6e-17 61.7 0.2 1.2e-16 60.6 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pan_kinase PF03309.14 OAG24483.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase Hexokinase_2 PF03727.16 OAG24484.1 - 2.4e-74 249.8 0.0 3.3e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG24484.1 - 1.7e-67 227.2 0.0 2.7e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase HNH PF01844.23 OAG24486.1 - 0.0057 16.8 1.0 0.011 15.8 1.0 1.5 1 0 0 1 1 1 1 HNH endonuclease PP28 PF10252.9 OAG24487.1 - 9e-27 93.4 18.6 9e-27 93.4 18.6 3.2 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Piwi PF02171.17 OAG24488.1 - 3.2e-75 253.2 0.0 4.6e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 OAG24488.1 - 3.8e-17 61.7 0.3 1.1e-16 60.2 0.3 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OAG24488.1 - 1.1e-16 61.7 0.0 2.6e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 OAG24488.1 - 1.5e-15 57.2 0.2 2.5e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 OAG24488.1 - 7.9e-13 48.5 0.0 1.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAG24488.1 - 8.9e-07 29.1 0.0 2.5e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 OAG24489.1 - 1.6e-91 307.4 17.1 9.8e-89 298.2 0.0 4.7 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAG24489.1 - 2.5e-05 24.7 7.4 0.0049 17.6 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat HAT PF02184.16 OAG24489.1 - 0.011 15.6 8.9 0.05 13.6 0.3 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 OAG24489.1 - 0.013 16.0 2.8 0.051 14.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG24489.1 - 0.06 14.0 6.2 0.084 13.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG24489.1 - 0.11 13.1 0.3 3.7 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat UNC-50 PF05216.13 OAG24490.1 - 7.6e-84 280.7 15.9 8.6e-84 280.5 15.9 1.0 1 0 0 1 1 1 1 UNC-50 family GTP_EFTU PF00009.27 OAG24491.1 - 5.5e-32 110.9 4.4 4.4e-30 104.7 4.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG24491.1 - 1.1e-25 89.7 1.3 2.7e-25 88.5 1.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAG24491.1 - 2.6e-09 37.2 0.2 5.9e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 OAG24491.1 - 3.1e-09 36.5 0.0 8.4e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 OAG24491.1 - 5.3e-05 23.2 0.4 0.0014 18.5 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OAG24491.1 - 0.00012 21.7 0.2 0.00027 20.5 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 OAG24491.1 - 0.00035 20.1 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG24491.1 - 0.002 17.6 3.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit zf-CCHC PF00098.23 OAG24491.1 - 0.0024 17.9 3.3 0.0026 17.8 1.4 2.1 2 0 0 2 2 1 1 Zinc knuckle GTP_EFTU_D2 PF03144.25 OAG24491.1 - 0.02 15.3 6.0 2.9 8.3 0.4 3.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Pex14_N PF04695.13 OAG24491.1 - 0.021 15.5 0.5 0.021 15.5 0.5 2.8 2 1 1 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roc PF08477.13 OAG24491.1 - 0.021 15.0 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase OAM_dimer PF16554.5 OAG24491.1 - 0.091 13.2 0.9 0.25 11.8 0.9 1.7 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase ATP_bind_1 PF03029.17 OAG24491.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mfp-3 PF04202.13 OAG24491.1 - 0.2 12.1 0.9 0.67 10.4 0.6 2.0 2 0 0 2 2 2 0 Foot protein 3 Dynamin_N PF00350.23 OAG24491.1 - 1.2 9.2 5.6 5.7 7.0 0.1 3.4 3 1 1 4 4 4 0 Dynamin family p450 PF00067.22 OAG24492.1 - 5.7e-54 183.6 0.0 8.2e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhoH PF02562.16 OAG24492.1 - 0.17 11.3 0.1 0.95 8.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Glyco_hydro_18 PF00704.28 OAG24493.1 - 9.6e-83 278.5 5.2 1.3e-82 278.1 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cation_efflux PF01545.21 OAG24493.1 - 0.057 13.1 0.4 0.089 12.5 0.4 1.2 1 0 0 1 1 1 0 Cation efflux family DnaJ PF00226.31 OAG24494.1 - 5e-07 29.8 0.7 1.2e-06 28.5 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.13 OAG24496.1 - 6.5e-53 179.7 0.0 7.8e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG24496.1 - 0.0085 15.0 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG24496.1 - 0.043 13.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family RCC1 PF00415.18 OAG24497.1 - 2.6e-30 104.8 0.3 1.3e-06 28.9 0.0 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG24497.1 - 2.1e-15 56.1 17.9 2.2e-09 36.9 0.1 7.1 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.15 OAG24498.1 - 2.2e-49 167.2 2.9 5e-49 166.0 2.9 1.6 1 0 0 1 1 1 1 Sec34-like family BST2 PF16716.5 OAG24498.1 - 0.67 10.6 7.2 0.078 13.6 1.5 2.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 VP4_2 PF08935.10 OAG24499.1 - 0.083 13.5 0.9 0.27 11.8 0.7 1.9 2 0 0 2 2 2 0 Viral protein VP4 subunit adh_short_C2 PF13561.6 OAG24500.1 - 1e-55 188.9 0.8 1.5e-55 188.3 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24500.1 - 4.4e-48 163.3 3.8 5.4e-48 163.0 3.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24500.1 - 7.9e-10 38.9 0.5 1.1e-09 38.4 0.5 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG24500.1 - 0.0085 15.4 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 OAG24500.1 - 0.19 11.8 3.1 0.44 10.6 3.1 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3829 PF12889.7 OAG24500.1 - 0.24 10.8 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Zn_clus PF00172.18 OAG24501.1 - 2.9e-08 33.7 13.9 6.8e-08 32.5 13.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG24501.1 - 3.4e-06 26.3 1.3 9.9e-06 24.8 0.4 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG24501.1 - 9.8e-05 22.6 11.1 0.00084 19.7 0.5 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG24501.1 - 0.05 14.5 0.4 0.05 14.5 0.4 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger SPX PF03105.19 OAG24501.1 - 1.5 8.6 7.9 2.5 7.9 7.9 1.4 1 0 0 1 1 1 0 SPX domain FAM70 PF14967.6 OAG24501.1 - 2.5 7.5 8.3 5.2 6.4 8.3 1.5 1 0 0 1 1 1 0 FAM70 protein Pex14_N PF04695.13 OAG24501.1 - 3.7 8.2 10.9 10 6.8 10.9 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAT PF16073.5 OAG24502.1 - 2.7e-79 266.3 2.3 1.2e-78 264.2 0.7 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 OAG24502.1 - 1.4e-78 264.0 0.0 4.1e-78 262.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG24502.1 - 1.6e-41 142.9 0.0 3e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG24502.1 - 1.4e-33 115.4 2.5 1.4e-33 115.4 2.5 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 OAG24502.1 - 4.3e-23 82.6 0.1 3.7e-20 73.0 0.0 3.4 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 OAG24502.1 - 3.1e-22 78.7 7.0 5.2e-11 42.7 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 OAG24502.1 - 1e-14 54.5 0.0 2.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OAG24502.1 - 1.8e-08 34.8 1.2 5.4e-08 33.3 0.0 2.5 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 OAG24502.1 - 4.9e-05 24.0 1.8 0.0097 16.5 0.1 2.9 3 0 0 3 3 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 OAG24502.1 - 0.00043 19.7 0.0 0.0013 18.1 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 OAG24502.1 - 0.011 15.5 0.2 1 9.1 0.0 2.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG24502.1 - 0.07 12.8 0.1 0.94 9.1 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG24502.1 - 0.089 12.6 0.3 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OAG24502.1 - 0.095 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Prefoldin PF02996.17 OAG24504.1 - 3e-36 124.0 0.2 7.4e-36 122.7 0.0 1.6 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAG24504.1 - 4.6e-05 23.3 0.7 0.0027 17.6 0.1 2.7 1 1 1 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 OAG24504.1 - 0.00091 19.7 2.6 0.3 11.7 0.1 2.2 1 1 1 2 2 2 2 Syntaxin 6, N-terminal APG17 PF04108.12 OAG24504.1 - 0.0031 16.7 0.8 0.007 15.5 0.1 1.7 2 0 0 2 2 2 1 Autophagy protein Apg17 DUF1664 PF07889.12 OAG24504.1 - 0.007 16.4 0.4 1.9 8.5 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) DUF4201 PF13870.6 OAG24504.1 - 0.0091 15.7 0.5 0.41 10.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) End3 PF12761.7 OAG24504.1 - 0.021 15.0 0.8 0.064 13.4 0.2 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 BST2 PF16716.5 OAG24504.1 - 0.023 15.3 2.7 4.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 OAG24504.1 - 0.048 14.0 0.6 3.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 OAG24504.1 - 0.068 13.4 3.9 0.5 10.6 0.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Lebercilin PF15619.6 OAG24504.1 - 0.095 12.3 6.0 0.24 11.0 0.9 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 OAG24504.1 - 0.3 11.7 3.5 2 9.1 0.2 2.7 3 0 0 3 3 3 0 SlyX CC2-LZ PF16516.5 OAG24504.1 - 0.63 10.4 8.3 6.1 7.3 0.4 2.5 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sarcoglycan_1 PF04790.13 OAG24505.1 - 0.097 12.0 1.1 0.2 11.0 1.1 1.4 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Ribo_biogen_C PF04034.13 OAG24506.1 - 1.5e-49 166.9 0.0 2.1e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAG24506.1 - 2.5e-10 40.0 0.6 5.4e-10 38.9 0.6 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 OAG24506.1 - 0.0019 17.6 18.7 0.0028 17.1 18.7 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 OAG24506.1 - 5 6.4 22.7 9.9 5.5 22.7 1.5 1 0 0 1 1 1 0 SDA1 VHS PF00790.19 OAG24507.1 - 1.8e-48 164.0 0.0 3.9e-48 162.9 0.0 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OAG24507.1 - 3.8e-22 78.4 1.5 2.1e-21 76.0 0.1 2.9 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 OAG24507.1 - 5e-18 65.4 1.9 5e-18 65.4 1.9 2.7 2 1 1 3 3 3 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 OAG24507.1 - 9e-08 31.6 0.2 2e-06 27.3 0.0 3.0 3 0 0 3 3 3 1 GGA N-GAT domain Mei5 PF10376.9 OAG24507.1 - 0.031 14.2 0.7 0.074 12.9 0.7 1.7 1 0 0 1 1 1 0 Double-strand recombination repair protein MAPEG PF01124.18 OAG24508.1 - 1.6e-19 70.1 2.4 1.8e-19 69.9 2.4 1.1 1 0 0 1 1 1 1 MAPEG family UPF0203 PF05254.12 OAG24509.1 - 2.4e-26 91.7 2.6 2.8e-26 91.5 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 OAG24509.1 - 0.00021 21.6 0.6 0.00021 21.6 0.6 1.9 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 OAG24509.1 - 0.0016 18.5 3.7 0.041 13.9 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 OAG24509.1 - 0.0098 16.1 4.1 0.4 10.9 0.3 2.2 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 OAG24509.1 - 1.2 10.1 4.2 13 6.7 1.6 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5339) DNA_pol_A_exo1 PF01612.20 OAG24510.1 - 1.1e-38 132.7 0.2 1.8e-38 132.0 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAG24510.1 - 1.6e-26 92.8 0.2 3.7e-25 88.4 0.1 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAG24510.1 - 1e-09 38.2 0.0 2.8e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Rsd_AlgQ PF04353.13 OAG24510.1 - 0.056 13.4 0.1 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Med19 PF10278.9 OAG24510.1 - 0.15 12.0 7.2 0.39 10.6 7.2 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Phage_holin_7_1 PF16081.5 OAG24510.1 - 5.7 7.1 6.8 17 5.6 6.8 1.7 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2263 PF10021.9 OAG24511.1 - 1.5e-18 67.6 0.1 5.5e-18 65.8 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAG24511.1 - 0.0086 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain Prenylcys_lyase PF07156.14 OAG24513.1 - 1.4e-102 343.6 0.0 1.8e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 OAG24513.1 - 1e-12 48.1 0.0 3.1e-11 43.2 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG24513.1 - 4.3e-12 46.1 0.0 9.3e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG24513.1 - 7e-09 35.9 0.2 0.00037 20.5 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAG24513.1 - 2.1e-08 34.2 0.0 3.2e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG24513.1 - 2.5e-05 23.7 0.1 0.0033 16.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG24513.1 - 0.0017 18.9 0.2 1.5 9.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG24513.1 - 0.002 16.9 0.9 0.41 9.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OAG24513.1 - 0.0034 16.7 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG24513.1 - 0.036 13.4 0.4 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG24513.1 - 0.087 12.1 0.3 0.24 10.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 OAG24513.1 - 0.093 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family ApbA PF02558.16 OAG24513.1 - 0.099 12.3 0.3 0.74 9.4 0.2 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG24513.1 - 0.2 10.7 0.8 0.31 10.1 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Toxin_32 PF08120.11 OAG24514.1 - 0.22 11.4 1.1 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Tamulustoxin family Ribosomal_L31 PF01197.18 OAG24516.1 - 0.00093 19.4 0.0 0.0029 17.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L31 Flavin_Reduct PF01613.18 OAG24517.1 - 2.1e-20 73.4 0.1 4.6e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Flavin reductase like domain Peptidase_M32 PF02074.15 OAG24517.1 - 0.24 10.1 2.1 0.45 9.2 0.6 1.9 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase LSM PF01423.22 OAG24518.1 - 4.1e-18 64.8 0.1 5.1e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG24518.1 - 0.0022 18.1 0.1 0.0028 17.8 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain TauD PF02668.16 OAG24519.1 - 3.6e-27 95.8 0.0 5.1e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 OAG24519.1 - 0.003 17.8 0.1 0.0055 17.0 0.1 1.4 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 DUF1744 PF08490.12 OAG24520.1 - 4.5e-157 522.7 0.0 7.1e-157 522.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAG24520.1 - 2.5e-81 273.4 3.2 2.5e-81 273.4 3.2 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAG24520.1 - 1.9e-15 56.6 0.7 8.1e-13 47.9 0.1 3.7 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAG24520.1 - 8.1e-09 35.5 0.1 2.9e-08 33.7 0.1 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAG24520.1 - 1e-06 28.8 1.5 0.00023 21.2 0.0 2.9 2 0 0 2 2 2 2 RNase_H superfamily DUF3767 PF12597.8 OAG24521.1 - 7.1e-30 102.8 1.2 7.5e-30 102.7 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) SHR3_chaperone PF08229.11 OAG24521.1 - 0.72 8.8 2.4 1.3 8.0 2.3 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 PBP_sp32 PF07222.12 OAG24521.1 - 0.95 8.9 5.5 1.3 8.4 5.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Tho2 PF11262.8 OAG24521.1 - 1.4 8.0 5.7 1.7 7.7 5.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MTS PF05175.14 OAG24522.1 - 7.3e-05 22.4 0.0 0.00014 21.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG24522.1 - 0.028 15.2 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG24522.1 - 0.038 14.7 0.0 0.071 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.6 OAG24523.1 - 6e-19 68.6 0.4 8.7e-19 68.1 0.0 1.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAG24523.1 - 4.6e-11 42.6 0.1 1e-10 41.5 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CSTF2_hinge PF14327.6 OAG24523.1 - 0.044 14.2 0.8 0.077 13.5 0.8 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 ERp29 PF07749.12 OAG24523.1 - 0.079 13.9 1.0 0.13 13.1 1.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain CBS PF00571.28 OAG24526.1 - 4.4e-20 71.9 4.2 1.4e-05 25.4 0.0 5.3 5 0 0 5 5 5 5 CBS domain Ribosomal_L11_N PF03946.14 OAG24528.1 - 2.3e-25 88.2 0.1 4.3e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAG24528.1 - 7.6e-14 52.0 0.2 1.3e-13 51.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_hydro_20 PF00728.22 OAG24530.1 - 3.8e-95 319.3 0.5 4.8e-95 318.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG24530.1 - 1.1e-24 87.6 0.0 2.8e-24 86.3 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG24530.1 - 5.5e-06 27.2 0.1 2.1e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Big_5 PF13205.6 OAG24531.1 - 0.013 16.2 4.5 0.021 15.5 4.5 1.4 1 1 0 1 1 1 0 Bacterial Ig-like domain HET PF06985.11 OAG24532.1 - 9e-25 87.7 0.0 1.7e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RMI1_N PF08585.12 OAG24533.1 - 9.6e-62 208.6 0.0 1.1e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 OAG24534.1 - 6.5e-33 112.7 0.0 1.4e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 OAG24534.1 - 0.0012 19.0 0.1 0.0031 17.7 0.1 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 OAG24534.1 - 0.0042 15.8 0.6 0.0062 15.3 0.6 1.2 1 0 0 1 1 1 1 Dor1-like family Dopey_N PF04118.14 OAG24535.1 - 9.6e-118 392.7 0.0 2.6e-117 391.4 0.0 1.8 1 0 0 1 1 1 1 Dopey, N-terminal HTH_23 PF13384.6 OAG24535.1 - 0.027 14.3 0.0 0.09 12.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HEAT_EZ PF13513.6 OAG24535.1 - 0.34 11.5 2.1 90 3.7 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat TMEM52 PF14979.6 OAG24536.1 - 0.16 11.9 0.5 0.23 11.4 0.5 1.4 1 0 0 1 1 1 0 Transmembrane 52 DUF5522 PF17653.1 OAG24539.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) CXCL17 PF15211.6 OAG24540.1 - 0.037 14.8 0.5 0.043 14.6 0.5 1.1 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 zf-C2H2_4 PF13894.6 OAG24541.1 - 1.2e-05 25.7 9.6 0.12 13.3 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG24541.1 - 0.00042 20.6 14.4 0.018 15.5 0.1 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG24541.1 - 0.00084 19.9 1.1 0.046 14.4 0.0 2.4 2 0 0 2 2 2 1 FOXP coiled-coil domain DAO PF01266.24 OAG24542.1 - 2.6e-32 112.8 0.0 3.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 OAG24542.1 - 0.00045 19.6 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 OAG24542.1 - 0.00051 19.2 0.1 0.00098 18.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG24542.1 - 0.016 15.4 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 OAG24542.1 - 0.06 13.3 0.2 0.24 11.4 0.2 1.7 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 OAG24542.1 - 0.06 12.4 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OAG24542.1 - 0.073 12.1 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG24542.1 - 0.075 12.3 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG24542.1 - 0.1 13.2 0.0 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG24542.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 OAG24542.1 - 0.17 11.6 0.0 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 OAG24542.1 - 0.17 11.8 0.2 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding RrnaAD PF00398.20 OAG24543.1 - 4.1e-07 29.3 0.0 7.2e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase THUMP PF02926.17 OAG24544.1 - 1.7e-12 47.6 0.0 3.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 THUMP domain RS4NT PF08071.12 OAG24544.1 - 0.17 12.0 0.3 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 RS4NT (NUC023) domain APH PF01636.23 OAG24545.1 - 4e-06 26.9 0.0 5.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Amidase PF01425.21 OAG24546.1 - 3.6e-105 352.5 0.0 4.8e-105 352.1 0.0 1.2 1 0 0 1 1 1 1 Amidase EBP PF05241.12 OAG24547.1 - 1.4e-56 190.8 11.0 1.7e-56 190.4 11.0 1.1 1 0 0 1 1 1 1 Emopamil binding protein Fra10Ac1 PF09725.9 OAG24547.1 - 0.021 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_88 PF07470.13 OAG24548.1 - 2.2e-55 188.1 0.3 2.6e-55 187.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 PI-PLC-C1 PF16670.5 OAG24550.1 - 3.9e-127 423.9 0.0 4.5e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent adh_short PF00106.25 OAG24551.1 - 1.7e-37 128.8 0.0 8.6e-37 126.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24551.1 - 8.1e-26 91.0 0.0 2.3e-25 89.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24551.1 - 5.1e-09 36.3 0.0 6.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAG24551.1 - 0.023 14.2 0.2 0.034 13.7 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Thi4 PF01946.17 OAG24551.1 - 0.031 13.5 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GDP_Man_Dehyd PF16363.5 OAG24551.1 - 0.067 12.6 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG24551.1 - 0.069 13.0 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Syja_N PF02383.18 OAG24552.1 - 1.4e-92 310.5 0.0 2.1e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAG24552.1 - 4.1e-34 116.7 0.0 7.9e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Sugar_tr PF00083.24 OAG24554.1 - 1.7e-111 373.3 16.0 2e-111 373.0 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG24554.1 - 1.7e-30 106.2 28.0 4.5e-28 98.2 14.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG24554.1 - 9.3e-06 24.3 2.0 1.4e-05 23.8 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OAG24554.1 - 0.00097 18.2 1.1 0.0027 16.7 1.1 1.7 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM HET PF06985.11 OAG24555.1 - 3e-09 37.4 12.9 9.1e-09 35.8 2.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pyridoxal_deC PF00282.19 OAG24556.1 - 5.8e-75 252.4 0.0 7.6e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans PF04082.18 OAG24557.1 - 8.7e-16 57.7 0.6 1.6e-15 56.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24557.1 - 4.1e-07 30.0 14.2 8.8e-07 28.9 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG24559.1 - 9.9e-44 149.6 0.3 1.3e-43 149.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24559.1 - 1.7e-42 145.1 0.1 2.2e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24559.1 - 1.2e-10 41.6 0.3 2.2e-10 40.7 0.3 1.4 1 1 0 1 1 1 1 KR domain DUF1989 PF09347.10 OAG24560.1 - 5.2e-61 205.1 0.0 6.3e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HMGL-like PF00682.19 OAG24561.1 - 1.7e-78 263.8 0.0 2.4e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OAG24561.1 - 2e-22 79.5 0.2 5.8e-22 78.0 0.2 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF348 PF03990.14 OAG24561.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain DUF2347 PF09804.9 OAG24562.1 - 2.6e-86 289.7 0.0 4.1e-86 289.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 OAG24562.1 - 1.1e-33 117.1 16.7 2.4e-18 67.0 0.3 3.9 2 1 2 4 4 4 3 Domain of unknown function (DUF4484) Avl9 PF09794.9 OAG24562.1 - 0.0023 16.7 0.0 2.1 7.0 0.0 2.7 3 0 0 3 3 3 2 Transport protein Avl9 SPA PF08616.10 OAG24562.1 - 0.0069 16.3 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 Stabilization of polarity axis HlyIII PF03006.20 OAG24563.1 - 1.5e-41 142.6 6.7 1.9e-41 142.3 6.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF308 PF03729.13 OAG24563.1 - 2.1 8.8 15.5 0.1 13.0 1.1 3.7 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) adh_short_C2 PF13561.6 OAG24565.1 - 8.5e-44 149.9 0.0 4.9e-25 88.5 0.2 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24565.1 - 3e-27 95.4 0.2 1.3e-24 86.7 0.2 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG24565.1 - 5.4e-11 42.7 0.1 1.1e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG24565.1 - 0.00028 20.4 0.1 0.0011 18.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAG24565.1 - 0.00095 19.2 1.8 0.0018 18.4 1.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDP_Man_Dehyd PF16363.5 OAG24565.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Dexa_ind PF15198.6 OAG24565.1 - 0.095 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Dexamethasone-induced Carb_anhydrase PF00194.21 OAG24566.1 - 2.6e-18 66.5 0.1 6.7e-18 65.1 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Aldolase_II PF00596.21 OAG24567.1 - 2.8e-49 167.6 0.0 3.5e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Defensin_4 PF07936.12 OAG24567.1 - 0.14 12.0 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 Potassium-channel blocking toxin HET PF06985.11 OAG24568.1 - 1.7e-14 54.4 3.3 2.8e-13 50.4 3.3 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 OAG24569.1 - 2.7e-37 128.6 0.4 3.7e-36 124.8 0.4 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1996 PF09362.10 OAG24570.1 - 1.7e-80 270.4 0.8 2.3e-80 270.0 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ses_B PF17046.5 OAG24571.1 - 0.12 12.3 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein BP28CT PF08146.12 OAG24572.1 - 1.2e-35 122.7 0.6 5.9e-35 120.5 0.6 2.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAG24572.1 - 1.9e-18 66.9 3.4 1.9e-18 66.9 3.4 6.2 7 1 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 OAG24572.1 - 1e-07 32.2 13.8 0.028 14.8 0.7 7.6 8 0 0 8 8 8 3 HEAT repeats HEAT PF02985.22 OAG24572.1 - 0.00017 21.5 0.1 0.00017 21.5 0.1 9.3 11 0 0 11 11 11 1 HEAT repeat Cnd1 PF12717.7 OAG24572.1 - 0.0024 17.9 0.0 0.0024 17.9 0.0 4.1 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG24572.1 - 0.0091 16.5 0.8 0.0091 16.5 0.8 8.1 10 1 0 10 10 10 1 HEAT-like repeat CLASP_N PF12348.8 OAG24572.1 - 0.018 14.6 0.4 0.18 11.3 0.0 2.8 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.23 OAG24572.1 - 0.085 12.9 14.7 2.3 8.4 0.1 5.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OAG24572.1 - 5 5.6 22.0 0.23 10.0 0.2 5.3 5 2 0 5 5 5 0 Adaptin N terminal region NRDE-2 PF08424.10 OAG24573.1 - 7.7e-87 291.4 2.5 3.3e-86 289.4 0.2 2.8 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 OAG24573.1 - 0.0033 18.1 3.2 17 6.6 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat Oxysterol_BP PF01237.18 OAG24574.1 - 2.7e-137 457.6 0.0 2.7e-137 457.6 0.0 2.4 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_5 PF13857.6 OAG24574.1 - 1.6e-17 63.3 0.3 4.6e-11 42.7 0.1 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG24574.1 - 2.7e-15 56.7 0.0 2.4e-07 31.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 OAG24574.1 - 9.9e-13 48.5 0.7 2e-12 47.5 0.7 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 OAG24574.1 - 2e-11 43.1 0.1 8.9e-05 22.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAG24574.1 - 2.3e-11 44.0 0.0 0.00022 21.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG24574.1 - 2.9e-11 43.3 0.1 7e-05 23.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 OAG24574.1 - 2.1e-07 31.1 0.9 6.5e-07 29.5 0.9 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OAG24574.1 - 6.4e-05 23.3 4.8 0.00013 22.4 3.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain ATP12 PF07542.11 OAG24575.1 - 4.3e-42 143.2 0.4 7.6e-42 142.4 0.4 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Mito_fiss_reg PF05308.11 OAG24575.1 - 0.31 11.1 3.6 0.5 10.4 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.18 OAG24576.1 - 3.1e-28 98.6 0.0 1.1e-26 93.5 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24576.1 - 8.6e-08 32.2 8.4 1.4e-07 31.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup54 PF13874.6 OAG24576.1 - 0.055 13.6 0.2 0.33 11.0 0.2 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1647 PF07801.11 OAG24576.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) DUF282 PF03380.14 OAG24577.1 - 0.023 14.6 0.2 0.053 13.4 0.2 1.6 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 zf-C2H2_4 PF13894.6 OAG24577.1 - 0.54 11.2 4.2 2.8 9.0 1.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger BLOC1_2 PF10046.9 OAG24579.1 - 0.0019 18.4 0.8 0.0074 16.6 0.4 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 OAG24579.1 - 0.041 13.3 0.8 0.078 12.4 0.1 1.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) T2SSM PF04612.12 OAG24579.1 - 0.044 13.8 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M SlyX PF04102.12 OAG24579.1 - 0.046 14.3 2.8 0.074 13.7 0.9 2.3 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 OAG24579.1 - 0.052 13.9 0.5 0.13 12.6 0.5 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain MscS_porin PF12795.7 OAG24579.1 - 0.055 13.0 2.7 0.39 10.2 2.0 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 OAG24579.1 - 0.091 12.8 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 OAG24579.1 - 0.12 12.3 1.5 3.1 7.8 1.4 2.5 2 0 0 2 2 2 0 FlxA-like protein ADIP PF11559.8 OAG24579.1 - 0.15 12.2 0.7 2 8.5 0.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 OAG24579.1 - 0.15 12.3 0.5 0.32 11.3 0.4 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.8 OAG24579.1 - 0.15 12.2 0.4 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 OAG24579.1 - 0.16 12.3 0.5 1.3 9.4 0.1 2.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 OAG24579.1 - 0.16 12.4 2.5 0.83 10.2 0.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PigN PF04987.14 OAG24580.1 - 3.3e-157 524.0 30.2 4.4e-157 523.6 30.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 OAG24580.1 - 3e-09 36.9 5.2 5.1e-08 32.9 5.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG24580.1 - 1.5e-07 31.2 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OAG24580.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Baculo_ODV-E27 PF05314.11 OAG24580.1 - 0.0022 17.2 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Baculovirus occlusion-derived virus envelope protein EC27 Alk_phosphatase PF00245.20 OAG24580.1 - 0.047 12.6 0.1 0.095 11.6 0.1 1.4 1 0 0 1 1 1 0 Alkaline phosphatase PglZ PF08665.12 OAG24580.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Tetraspanin PF00335.20 OAG24580.1 - 0.59 9.8 6.4 12 5.5 1.9 2.9 2 0 0 2 2 2 0 Tetraspanin family GDI PF00996.18 OAG24581.1 - 2.4e-194 645.8 0.0 2.8e-194 645.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAG24581.1 - 0.022 14.9 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG24581.1 - 0.09 13.4 0.2 0.32 11.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MRP-L47 PF06984.13 OAG24582.1 - 2.8e-18 65.8 1.1 2.8e-18 65.8 1.1 1.5 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DDE_Tnp_ISL3 PF01610.17 OAG24582.1 - 0.16 11.7 1.3 0.23 11.1 1.3 1.2 1 0 0 1 1 1 0 Transposase SUZ PF12752.7 OAG24582.1 - 3.2 8.6 5.4 1.9 9.3 1.4 2.2 2 0 0 2 2 2 0 SUZ domain bZIP_1 PF00170.21 OAG24583.1 - 9.9e-07 28.8 7.0 1.4e-06 28.3 7.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG24583.1 - 1.4e-06 28.3 9.5 4e-06 26.8 9.5 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG24583.1 - 0.0023 18.4 5.8 0.004 17.7 5.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 OAG24583.1 - 0.0069 15.7 1.3 0.0075 15.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) WD40_alt PF14077.6 OAG24583.1 - 0.019 14.9 1.7 0.089 12.7 1.7 2.1 1 1 1 2 2 2 0 Alternative WD40 repeat motif ZapB PF06005.12 OAG24583.1 - 0.02 15.3 1.8 0.035 14.5 1.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 OAG24583.1 - 0.026 14.3 0.8 0.039 13.7 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 OAG24583.1 - 0.12 13.0 0.8 0.19 12.4 0.8 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Macoilin PF09726.9 OAG24583.1 - 0.24 9.9 8.4 0.28 9.7 8.4 1.0 1 0 0 1 1 1 0 Macoilin family KLRAQ PF10205.9 OAG24583.1 - 0.41 10.9 6.0 0.071 13.4 2.3 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein NUDE_C PF04880.13 OAG24583.1 - 6.8 7.1 17.6 0.21 12.1 2.5 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Striatin PF08232.12 OAG24583.1 - 6.8 7.3 11.0 1.8 9.2 0.5 2.1 1 1 1 2 2 2 0 Striatin family Peptidase_M3 PF01432.20 OAG24585.1 - 5.5e-159 530.3 0.2 7.3e-159 529.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF2540 PF10802.8 OAG24586.1 - 0.046 13.8 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) ZnuA PF01297.17 OAG24586.1 - 0.14 11.5 1.2 0.16 11.4 1.2 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic AA_permease_2 PF13520.6 OAG24587.1 - 3.5e-59 200.7 48.1 4.4e-59 200.4 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG24587.1 - 9.4e-34 116.8 42.2 1.3e-33 116.3 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 OAG24588.1 - 5.3e-16 58.6 6.3 5.2e-15 55.4 6.3 2.2 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG24588.1 - 6.6e-09 35.7 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like SMC_N PF02463.19 OAG24589.1 - 4.5e-59 199.6 24.0 5e-58 196.1 24.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG24589.1 - 5.4e-20 71.9 4.0 8e-20 71.3 0.2 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG24589.1 - 3.8e-10 40.1 0.5 0.00052 19.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG24589.1 - 2e-08 35.0 15.3 2e-08 35.0 15.3 6.6 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 OAG24589.1 - 0.0012 18.6 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 OAG24589.1 - 0.014 16.0 13.5 0.014 16.0 13.5 9.4 3 2 5 8 8 8 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 OAG24589.1 - 0.058 13.9 0.0 0.058 13.9 0.0 5.5 3 3 0 3 3 3 0 ABC transporter Mce4_CUP1 PF11887.8 OAG24589.1 - 2.8 7.3 8.7 9 5.7 0.0 3.6 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative HD_3 PF13023.6 OAG24591.1 - 6.3e-49 166.1 0.1 8.1e-49 165.7 0.1 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAG24591.1 - 1.4e-12 47.8 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HAUS6_N PF14661.6 OAG24592.1 - 2.4e-49 168.0 3.8 2.4e-49 168.0 3.8 2.4 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus DUF2405 PF10293.9 OAG24592.1 - 0.049 13.6 0.9 0.18 11.8 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) Rib_hydrolayse PF02267.17 OAG24594.1 - 1.4e-08 34.4 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosyl cyclase Ank_2 PF12796.7 OAG24595.1 - 1.1e-15 57.9 0.0 0.0011 19.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG24595.1 - 3.5e-15 56.2 0.1 0.00037 21.0 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG24595.1 - 3.7e-13 48.4 3.0 0.18 12.5 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 OAG24595.1 - 3.8e-08 33.4 4.9 1.2 9.6 0.1 6.7 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG24595.1 - 3.5e-07 30.4 1.7 2.5 8.7 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat DUF249 PF03158.13 OAG24595.1 - 0.046 13.4 0.0 0.37 10.5 0.0 2.4 2 1 0 2 2 2 0 Multigene family 530 protein Glyco_transf_90 PF05686.12 OAG24596.1 - 1.1e-14 54.2 0.4 1.7e-09 37.1 0.0 3.5 3 1 1 4 4 4 2 Glycosyl transferase family 90 DUF3917 PF13055.6 OAG24596.1 - 0.088 13.2 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) TMEM100 PF16311.5 OAG24596.1 - 0.2 11.3 5.4 5.6 6.6 0.0 3.1 3 0 0 3 3 3 0 Transmembrane protein 100 Wzy_C PF04932.15 OAG24596.1 - 1 9.0 8.1 33 4.1 0.0 3.2 2 1 0 2 2 2 0 O-Antigen ligase MFS_1 PF07690.16 OAG24597.1 - 3.1e-18 65.8 29.4 3.1e-18 65.8 29.4 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_2 PF03446.15 OAG24598.1 - 1.1e-26 93.9 0.4 1.9e-26 93.1 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG24598.1 - 1.6e-08 34.8 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAG24598.1 - 3.5e-06 27.1 0.0 9.1e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG24598.1 - 4.2e-06 27.2 0.0 8.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 OAG24598.1 - 0.00016 21.3 0.0 0.00041 20.0 0.0 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 OAG24598.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG24598.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain BMC PF00936.19 OAG24598.1 - 0.013 15.5 0.2 0.032 14.2 0.2 1.7 1 0 0 1 1 1 0 BMC domain Ham1p_like PF01725.16 OAG24598.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Ham1 family Glu_dehyd_C PF16912.5 OAG24598.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAT PF04768.13 OAG24599.1 - 2.2e-54 183.6 0.0 4.1e-53 179.5 0.0 2.2 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Atg14 PF10186.9 OAG24599.1 - 0.051 12.7 0.7 0.076 12.1 0.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1772 PF08592.11 OAG24600.1 - 1.6e-22 80.3 0.7 2.2e-22 79.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NmrA PF05368.13 OAG24601.1 - 3.3e-30 105.4 0.0 4.5e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG24601.1 - 1.3e-11 44.8 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG24601.1 - 7.5e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG24601.1 - 0.03 14.8 0.1 0.064 13.7 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG24601.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG24601.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 OAG24601.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2709 PF10915.8 OAG24601.1 - 0.2 10.9 0.1 1.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2709) FAD_binding_3 PF01494.19 OAG24604.1 - 8.9e-16 58.1 4.1 2.7e-13 49.9 4.1 3.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG24604.1 - 2.8e-09 37.0 1.1 0.00089 18.9 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG24604.1 - 1.2e-08 34.6 0.1 0.00083 18.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG24604.1 - 4.9e-08 32.5 0.0 7.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG24604.1 - 6.7e-07 28.4 0.1 0.00082 18.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 OAG24604.1 - 5.9e-06 26.4 0.1 1.6e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG24604.1 - 8.4e-05 22.1 0.2 0.00018 21.0 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG24604.1 - 0.0001 21.5 0.5 0.063 12.3 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 OAG24604.1 - 0.00021 20.5 0.1 0.0038 16.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG24604.1 - 0.0013 18.1 0.0 0.013 14.8 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG24604.1 - 0.0036 16.7 0.1 0.62 9.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG24604.1 - 0.0043 16.4 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG24604.1 - 0.0088 16.6 0.0 0.041 14.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG24604.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family p450 PF00067.22 OAG24605.1 - 3.3e-58 197.6 0.0 9.3e-58 196.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 OAG24606.1 - 1.1e-49 168.8 0.1 1.2e-49 168.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BBE PF08031.12 OAG24607.1 - 0.28 11.3 1.2 0.54 10.4 1.2 1.5 1 0 0 1 1 1 0 Berberine and berberine like PALP PF00291.25 OAG24610.1 - 4.5e-64 216.7 0.2 5.6e-64 216.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OAG24610.1 - 9.2e-14 51.6 0.0 5.8e-09 36.3 0.0 3.4 3 0 0 3 3 3 2 CBS domain PAZ PF02170.22 OAG24611.1 - 0.00074 19.3 0.4 0.0017 18.2 0.4 1.6 1 1 0 1 1 1 1 PAZ domain SRPRB PF09439.10 OAG24612.1 - 1.4e-27 96.3 0.0 5.6e-27 94.3 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OAG24612.1 - 2.2e-05 24.0 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 OAG24612.1 - 0.00011 22.6 0.6 0.0011 19.4 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG24612.1 - 0.00036 20.6 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 OAG24612.1 - 0.0046 17.4 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 OAG24612.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OAG24612.1 - 0.014 15.2 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OAG24612.1 - 0.016 14.8 0.0 0.058 12.9 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.6 OAG24612.1 - 0.025 14.9 0.1 0.11 12.8 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG24612.1 - 0.041 14.1 0.0 0.078 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG24612.1 - 0.041 13.8 0.0 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 OAG24612.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OAG24612.1 - 0.078 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAG24612.1 - 0.087 12.5 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 OAG24612.1 - 0.094 12.9 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAG24612.1 - 0.1 11.7 0.0 4.1 6.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 OAG24612.1 - 0.11 11.8 0.1 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAG24612.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OAG24612.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NDT80_PhoG PF05224.12 OAG24613.1 - 2e-38 132.5 0.3 4.5e-38 131.3 0.3 1.6 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family HET PF06985.11 OAG24616.1 - 3.4e-27 95.6 0.1 5.5e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG24617.1 - 2.3e-18 66.2 0.1 3.8e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG24617.1 - 3.5e-09 36.7 11.3 8.9e-07 29.1 4.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG24617.1 - 0.00024 21.6 17.7 0.036 14.9 6.0 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAG24617.1 - 0.0086 16.3 4.9 0.022 15.0 4.9 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAG24617.1 - 0.025 15.0 17.7 0.38 11.3 7.8 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.7 OAG24617.1 - 2.2 8.4 5.5 2.2 8.3 3.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ETC_C1_NDUFA5 PF04716.14 OAG24619.1 - 4.8e-27 93.6 0.1 1.2e-25 89.1 0.1 2.3 2 0 0 2 2 2 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 OAG24620.1 - 2.9e-45 152.5 0.2 5.6e-25 87.3 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OAG24620.1 - 1.1e-11 45.0 0.0 4.9e-06 26.6 0.0 4.5 2 1 3 5 5 5 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG24620.1 - 1.3e-07 31.9 1.3 0.063 13.6 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG24620.1 - 1.5e-06 28.6 3.9 0.23 11.9 0.1 4.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG24620.1 - 3.1e-06 26.8 0.1 0.0047 16.3 0.1 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family HyaE PF07449.11 OAG24620.1 - 0.0037 17.2 0.0 10 6.1 0.0 3.6 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 OAG24620.1 - 0.045 13.9 0.7 0.32 11.2 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin_3 PF13192.6 OAG24620.1 - 0.053 13.6 0.0 0.74 9.9 0.0 2.9 4 0 0 4 4 4 0 Thioredoxin domain Rhodanese PF00581.20 OAG24621.1 - 2.5e-09 37.6 0.3 7.1e-09 36.2 0.3 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Csm4_C PF17953.1 OAG24621.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain MsyB PF13984.6 OAG24621.1 - 0.019 15.2 0.2 0.031 14.6 0.2 1.3 1 0 0 1 1 1 0 MsyB protein LacAB_rpiB PF02502.18 OAG24622.1 - 1.3e-45 154.8 0.4 1.8e-45 154.4 0.4 1.2 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 OAG24622.1 - 0.022 14.8 0.3 0.35 10.9 0.0 2.2 1 1 0 2 2 2 0 Glycine-rich SFCGS Peptidase_M1 PF01433.20 OAG24623.1 - 6.5e-42 143.5 0.1 1e-41 142.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OAG24623.1 - 1.7e-38 131.2 0.1 3.9e-38 130.0 0.1 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OAG24623.1 - 8.7e-29 101.0 0.1 1.3e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 OAG24623.1 - 0.29 11.5 3.5 1.7 9.1 1.7 2.6 2 1 0 2 2 2 0 M61 glycyl aminopeptidase LysM PF01476.20 OAG24624.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 LysM domain NUDIX PF00293.28 OAG24626.1 - 1.4e-21 76.9 0.1 1.9e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 OAG24626.1 - 0.0044 17.0 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 OAG24627.1 - 6e-33 114.0 0.0 1e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24627.1 - 4.5e-09 36.3 8.2 7.2e-09 35.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOT2_3_5 PF04153.18 OAG24628.1 - 6.9e-26 90.9 0.6 1.4e-25 89.9 0.6 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-CCHC PF00098.23 OAG24629.1 - 0.14 12.2 0.3 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle LpxB PF02684.15 OAG24629.1 - 0.22 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DIOX_N PF14226.6 OAG24631.1 - 1.1e-16 61.6 0.0 2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG24631.1 - 2.4e-16 60.1 0.0 5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG24632.1 - 1e-23 83.8 35.1 1e-23 83.8 35.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 OAG24633.1 - 3.3e-17 62.8 0.0 5.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG24633.1 - 0.0011 18.0 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OAG24633.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG24633.1 - 0.021 14.4 0.0 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase TGT PF01702.18 OAG24634.1 - 3.4e-143 477.0 0.0 4.2e-143 476.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M28 PF04389.17 OAG24635.1 - 5.7e-40 137.1 0.0 8.7e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG24635.1 - 1.7e-11 44.0 0.1 3.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG24635.1 - 0.00049 19.8 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Na_Ca_ex PF01699.24 OAG24636.1 - 2.2e-23 82.9 29.1 1e-11 45.0 8.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Mntp PF02659.15 OAG24636.1 - 0.02 14.6 0.3 0.02 14.6 0.3 2.6 3 0 0 3 3 3 0 Putative manganese efflux pump Spore_YabQ PF09578.10 OAG24636.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.9 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) DUF5083 PF16890.5 OAG24636.1 - 0.78 9.5 5.2 2.2 8.0 1.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5083) Ribosomal_S17e PF00833.18 OAG24637.1 - 1.1e-59 199.6 0.6 1.4e-59 199.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 OAG24637.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 GUCT (NUC152) domain IMS PF00817.20 OAG24639.1 - 0.0055 16.7 0.2 0.011 15.7 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family IFT20 PF14931.6 OAG24640.1 - 0.029 14.5 0.8 0.047 13.9 0.8 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Mit_ribos_Mrp51 PF11709.8 OAG24643.1 - 7.9e-112 374.5 4.6 2.9e-55 188.3 0.0 2.1 1 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit Y2_Tnp PF04986.13 OAG24643.1 - 0.033 14.3 0.1 0.077 13.0 0.0 1.6 1 1 0 1 1 1 0 Putative transposase DUF1838 PF08894.11 OAG24643.1 - 0.079 12.7 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) ERM PF00769.19 OAG24643.1 - 0.31 10.8 2.7 0.22 11.3 1.1 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RPAP2_Rtr1 PF04181.13 OAG24644.1 - 1.2e-21 76.8 0.1 2e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_2 PF07653.17 OAG24645.1 - 2.7e-10 39.8 0.1 5.5e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG24645.1 - 1.2e-09 37.6 0.2 2.5e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG24645.1 - 8.1e-09 35.2 0.3 1.5e-08 34.4 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 OAG24649.1 - 8.5e-38 130.2 41.1 8.5e-38 130.2 41.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG24649.1 - 1.1e-10 41.0 10.5 1.1e-10 41.0 10.5 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter C_Hendra PF16821.5 OAG24654.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses Pkinase PF00069.25 OAG24657.1 - 0.0053 16.1 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain peroxidase PF00141.23 OAG24658.1 - 2.4e-29 102.6 0.1 3.6e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG24658.1 - 0.075 13.0 0.0 0.37 10.7 0.0 2.2 3 0 0 3 3 3 0 Fungal peroxidase extension region GFA PF04828.14 OAG24660.1 - 8.7e-19 67.7 7.2 1.2e-08 35.2 0.4 3.6 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 OAG24661.1 - 0.0045 16.4 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1077 PF06417.12 OAG24662.1 - 5.8e-46 155.3 1.3 7e-46 155.1 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.6 OAG24662.1 - 8.3 5.3 6.3 7.2 5.5 5.4 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 Adaptin_N PF01602.20 OAG24663.1 - 1.4e-123 413.2 11.1 1.8e-123 412.9 11.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG24663.1 - 1.5e-57 194.2 8.8 3.7e-57 192.9 0.2 3.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG24663.1 - 2.8e-13 48.9 0.5 0.00023 21.2 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 OAG24663.1 - 8.1e-13 48.6 2.7 5.1e-07 30.0 0.0 4.6 4 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 OAG24663.1 - 1.6e-05 25.3 0.3 0.041 14.4 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 OAG24663.1 - 0.00025 20.7 1.0 0.16 11.5 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.23 OAG24663.1 - 0.00033 20.6 1.9 1.1 9.3 0.1 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 OAG24663.1 - 0.0072 16.5 1.3 1 9.5 0.1 3.4 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 OAG24663.1 - 0.019 14.7 0.0 25 4.5 0.0 3.8 2 2 0 3 3 3 0 DNA alkylation repair enzyme DUF2496 PF10689.9 OAG24663.1 - 0.028 14.2 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) DUF1774 PF08611.10 OAG24664.1 - 1.3e-32 111.9 0.0 1.3e-32 111.9 0.0 3.3 3 1 1 4 4 4 1 Fungal protein of unknown function (DUF1774) NADH_dehy_S2_C PF06444.11 OAG24664.1 - 0.25 11.9 7.0 4.2 8.0 1.0 2.8 1 1 1 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus Hist_deacetyl PF00850.19 OAG24665.1 - 3.7e-51 174.4 0.0 6.6e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_3 PF07859.13 OAG24665.1 - 4.8e-45 154.0 0.0 1.2e-44 152.8 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG24665.1 - 0.11 11.3 0.7 0.7 8.7 0.1 2.2 2 1 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.8 OAG24665.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAD_binding_4 PF01565.23 OAG24666.1 - 1.1e-22 80.3 0.2 3.3e-22 78.7 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG24666.1 - 0.00084 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 OAG24667.1 - 8.3e-29 100.8 0.7 1.4e-28 100.1 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 OAG24669.1 - 4.3e-09 36.3 17.6 0.00021 21.6 1.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG24669.1 - 7.5e-05 23.0 0.8 7.5e-05 23.0 0.8 4.6 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG24669.1 - 0.00038 21.1 25.6 0.098 13.6 1.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAG24669.1 - 0.00043 20.5 0.5 0.97 9.8 0.0 2.5 1 1 1 2 2 2 2 C2H2-type zinc ribbon IBR PF01485.21 OAG24669.1 - 0.03 14.6 3.3 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 OAG24669.1 - 0.33 11.0 7.9 0.86 9.7 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Aminotran_1_2 PF00155.21 OAG24671.1 - 9.6e-48 163.2 0.0 1.5e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Rad4 PF03835.15 OAG24671.1 - 9.7e-37 125.9 0.2 4.2e-36 123.8 0.2 2.2 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG24671.1 - 2.7e-29 101.4 0.1 5.4e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG24671.1 - 9.1e-18 63.8 0.1 2.1e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG24671.1 - 5.1e-14 53.0 1.3 5.1e-14 53.0 1.3 4.7 6 1 1 7 7 7 1 Rad4 beta-hairpin domain 2 Beta_elim_lyase PF01212.21 OAG24671.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Transglut_core PF01841.19 OAG24671.1 - 0.067 13.7 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Polysacc_deac_1 PF01522.21 OAG24672.1 - 1.8e-28 98.9 0.0 2.9e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG24672.1 - 2.5e-19 69.4 83.8 2.6e-08 34.2 13.3 3.9 4 0 0 4 4 4 3 Chitin recognition protein Glyco_hydro_57 PF03065.15 OAG24672.1 - 0.036 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAG24672.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) adh_short PF00106.25 OAG24673.1 - 1.9e-44 151.5 0.5 2.6e-44 151.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24673.1 - 2.1e-26 92.9 0.5 2.9e-26 92.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24673.1 - 9.9e-13 48.4 0.3 1.9e-12 47.4 0.3 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG24673.1 - 0.00086 18.5 0.1 0.0019 17.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG24673.1 - 0.0036 16.8 0.9 0.013 14.9 0.9 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 OAG24673.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda ATP-synt_E PF05680.12 OAG24674.1 - 0.15 12.4 11.5 0.93 9.9 11.5 2.5 1 0 0 1 1 1 0 ATP synthase E chain MFS_1 PF07690.16 OAG24675.1 - 3.7e-22 78.7 52.0 1e-21 77.3 29.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG24675.1 - 2.9e-05 22.7 1.4 6.3e-05 21.6 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DSX_dimer PF08828.10 OAG24675.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Doublesex dimerisation domain Lon_C PF05362.13 OAG24676.1 - 1.1e-65 221.1 0.0 2.3e-65 220.0 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG24676.1 - 9e-31 107.4 0.0 1.9e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG24676.1 - 9.3e-22 77.9 0.0 2.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 OAG24676.1 - 1.3e-07 31.9 0.0 5e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG24676.1 - 3.7e-07 30.2 0.0 1.4e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAG24676.1 - 5.5e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 OAG24676.1 - 2.5e-05 24.6 0.1 0.0014 18.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 OAG24676.1 - 3.5e-05 22.9 0.0 6.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 OAG24676.1 - 7.3e-05 22.6 0.0 0.00063 19.5 0.0 2.4 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG24676.1 - 0.00067 20.1 0.1 0.00067 20.1 0.1 3.2 3 1 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG24676.1 - 0.0032 17.2 0.0 0.0093 15.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAG24676.1 - 0.0099 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OAG24676.1 - 0.018 14.9 0.1 0.16 11.9 0.0 2.3 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 OAG24676.1 - 0.024 15.2 0.0 0.024 15.2 0.0 3.6 4 0 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 OAG24676.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAG24676.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG24676.1 - 0.075 13.3 0.0 20 5.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG24676.1 - 0.078 13.5 0.4 0.37 11.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 OAG24676.1 - 0.097 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 OAG24676.1 - 0.14 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAG24676.1 - 0.18 11.7 0.0 0.84 9.5 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Pkinase PF00069.25 OAG24677.1 - 2e-12 47.0 0.0 2.7e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24677.1 - 2.6e-11 43.3 0.0 2.9e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OAG24678.1 - 1.9e-10 40.7 0.5 0.11 12.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OAG24678.1 - 2.1e-10 40.9 0.1 0.045 14.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG24678.1 - 2.8e-09 36.4 0.4 0.085 13.5 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 OAG24678.1 - 1.7e-08 34.9 0.2 3.5e-06 27.5 0.0 4.0 2 2 2 4 4 4 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 OAG24678.1 - 5.8e-06 26.1 0.1 0.23 11.4 0.0 3.4 2 0 0 2 2 2 2 F-box-like Ank_5 PF13857.6 OAG24678.1 - 0.00046 20.4 0.1 11 6.5 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) F-box PF00646.33 OAG24678.1 - 0.0056 16.5 0.3 0.42 10.5 0.1 3.1 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 OAG24678.1 - 0.015 15.2 0.0 0.75 9.7 0.1 2.7 2 0 0 2 2 2 0 F-box THRAP3_BCLAF1 PF15440.6 OAG24679.1 - 6 5.8 68.7 0.045 12.8 42.4 2.1 2 0 0 2 2 2 0 THRAP3/BCLAF1 family Caldesmon PF02029.15 OAG24679.1 - 6.3 5.4 99.6 0.63 8.7 67.0 2.4 2 0 0 2 2 2 0 Caldesmon PAP2_3 PF14378.6 OAG24680.1 - 4.9e-27 94.8 12.3 3.7e-21 75.7 3.8 2.5 2 0 0 2 2 2 2 PAP2 superfamily BTB PF00651.31 OAG24681.1 - 7.9e-05 22.9 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Cyclin PF08613.11 OAG24682.1 - 5.8e-25 88.5 0.0 8.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin KRE9 PF05390.11 OAG24683.1 - 6.2e-15 55.8 9.0 6.2e-15 55.8 9.0 2.0 1 1 1 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 OAG24683.1 - 4.8e-13 49.7 3.9 7.7e-13 49.0 0.1 2.8 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M24 PF00557.24 OAG24684.1 - 4.1e-58 196.5 0.1 5.4e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG24684.1 - 4.5e-27 94.2 0.0 8.6e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SLT PF01464.20 OAG24685.1 - 0.027 14.1 0.4 0.38 10.4 0.0 2.6 3 1 0 3 3 3 0 Transglycosylase SLT domain Glyco_hydro_26 PF02156.15 OAG24686.1 - 1e-80 271.5 6.8 1.4e-80 271.1 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 OAG24686.1 - 3.7e-24 85.3 2.4 9e-24 84.1 2.4 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 OAG24686.1 - 8e-06 26.0 0.2 2.1e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 DUF5010 C-terminal domain bMG6 PF17962.1 OAG24686.1 - 0.032 14.4 0.2 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 Phage_lysis PF03245.13 OAG24686.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Mannitol_dh_C PF08125.13 OAG24687.1 - 6.3e-43 147.0 0.3 1e-42 146.3 0.3 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAG24687.1 - 1.3e-17 64.3 4.2 9e-17 61.6 0.1 2.7 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 OAG24687.1 - 0.0016 18.3 1.9 0.0038 17.1 0.2 2.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CdhD PF03599.16 OAG24687.1 - 0.015 14.0 0.1 0.029 13.1 0.1 1.6 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit UDPG_MGDP_dh_N PF03721.14 OAG24687.1 - 0.045 13.3 3.1 0.058 13.0 0.1 2.4 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 OAG24687.1 - 0.06 13.9 0.2 0.61 10.7 0.2 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Baculo_LEF-11 PF06385.12 OAG24687.1 - 0.13 12.8 1.6 12 6.5 0.2 2.8 3 0 0 3 3 3 0 Baculovirus LEF-11 protein Choline_transpo PF04515.12 OAG24688.1 - 1e-84 284.6 22.8 1e-84 284.6 22.8 2.5 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF4191 PF13829.6 OAG24688.1 - 3.6 6.9 10.4 3.8 6.8 5.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4191) Luteo_PO PF04662.13 OAG24689.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Luteovirus P0 protein ABC2_membrane_5 PF13346.6 OAG24689.1 - 0.037 13.6 0.1 0.037 13.6 0.1 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF5493 PF17597.2 OAG24689.1 - 4.7 7.5 8.4 5.1 7.4 3.8 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5493) ECM11 PF15463.6 OAG24690.1 - 1.2e-40 139.2 6.8 1.2e-40 139.2 6.8 2.8 3 0 0 3 3 3 1 Extracellular mutant protein 11 ApoO PF09769.9 OAG24690.1 - 0.037 14.0 1.9 0.12 12.4 0.5 2.4 2 0 0 2 2 2 0 Apolipoprotein O CPSase_L_D3 PF02787.19 OAG24690.1 - 0.044 14.1 0.5 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GIDA_assoc PF13932.6 OAG24690.1 - 0.16 12.1 4.1 6.1 7.0 0.2 2.5 2 0 0 2 2 2 0 GidA associated domain BST2 PF16716.5 OAG24690.1 - 0.81 10.3 10.8 9.3 6.9 2.7 2.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 F-box-like PF12937.7 OAG24691.1 - 0.00016 21.5 0.7 0.00032 20.5 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG24691.1 - 0.13 12.2 0.3 0.13 12.2 0.3 1.9 2 0 0 2 2 2 0 F-box domain NUDIX PF00293.28 OAG24692.1 - 7.2e-22 77.8 0.1 8.8e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Rep_1B PF17873.1 OAG24692.1 - 0.07 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Replicase polyprotein 1ab WD40 PF00400.32 OAG24693.1 - 2.1e-13 50.5 6.3 0.007 17.2 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.21 OAG24694.1 - 6.4e-33 114.0 13.0 6.4e-33 114.0 13.0 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 Aconitase PF00330.20 OAG24695.1 - 5.4e-161 536.7 0.0 6.6e-161 536.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG24695.1 - 2e-39 134.9 0.0 3.7e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CDC73_C PF05179.14 OAG24696.1 - 3.7e-49 166.4 0.0 5.2e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Glyco_hydro_3_C PF01915.22 OAG24697.1 - 1.5e-47 162.2 0.0 2.2e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG24697.1 - 1.5e-29 103.4 0.0 4e-29 102.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG24697.1 - 1.4e-26 92.4 0.1 2.5e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC2_membrane PF01061.24 OAG24698.1 - 2.8e-79 265.4 65.0 1.7e-41 142.0 26.2 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG24698.1 - 1.8e-36 125.7 0.0 1.5e-17 64.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG24698.1 - 4.3e-35 119.5 12.7 1.3e-31 108.3 0.6 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG24698.1 - 3.9e-15 56.2 0.0 3.9e-15 56.2 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG24698.1 - 1.8e-07 31.7 0.1 0.0003 21.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 OAG24698.1 - 2.8e-06 27.1 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG24698.1 - 1.8e-05 24.7 0.0 0.008 16.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG24698.1 - 2.4e-05 24.0 0.7 0.018 14.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OAG24698.1 - 2.5e-05 23.6 25.3 2.5e-05 23.6 25.3 4.5 2 2 1 4 4 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 OAG24698.1 - 3e-05 24.6 0.0 0.005 17.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG24698.1 - 0.00033 20.8 0.1 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG24698.1 - 0.00043 20.2 0.0 1.4 8.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAG24698.1 - 0.0022 18.3 0.8 0.95 9.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG24698.1 - 0.0042 17.1 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 OAG24698.1 - 0.0049 16.3 0.0 1.1 8.6 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 OAG24698.1 - 0.0057 16.3 0.7 0.077 12.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OAG24698.1 - 0.0073 16.0 0.0 0.98 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG24698.1 - 0.033 14.6 0.2 2.2 8.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAG24698.1 - 0.035 14.0 0.6 2.7 7.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAG24698.1 - 0.084 13.1 0.4 3.7 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG24698.1 - 0.091 13.2 0.0 2 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 OAG24698.1 - 0.1 12.5 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF2075 PF09848.9 OAG24698.1 - 0.16 11.2 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP41 PF04176.13 OAG24699.1 - 1.2e-72 243.0 0.1 1.5e-72 242.7 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 OAG24700.1 - 1.3e-70 237.8 0.0 1.8e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24700.1 - 6.7e-43 146.8 0.0 9.2e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG24700.1 - 1.4e-08 34.4 0.1 1.2e-07 31.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 OAG24700.1 - 0.00012 21.5 0.2 0.00021 20.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG24700.1 - 0.00018 20.6 0.4 0.00052 19.1 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG24700.1 - 0.0081 15.0 2.0 0.016 14.0 2.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAG24700.1 - 0.011 15.3 0.3 0.095 12.3 0.0 2.3 2 1 1 3 3 3 0 RIO1 family FTA2 PF13095.6 OAG24700.1 - 0.05 13.2 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG24700.1 - 0.056 13.3 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OAG24700.1 - 0.1 12.1 0.1 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_S8_N PF16361.5 OAG24700.1 - 0.1 13.1 0.6 0.24 11.9 0.3 1.7 1 1 0 1 1 1 0 N-terminal of Subtilase family AA_kinase PF00696.28 OAG24701.1 - 8.8e-40 136.8 0.8 8.8e-40 136.8 0.8 1.4 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 OAG24701.1 - 1.2e-14 54.0 1.8 3.3e-08 33.4 0.1 3.1 3 0 0 3 3 3 2 PUA domain Peptidase_M76 PF09768.9 OAG24702.1 - 7.5e-67 224.4 1.8 9e-67 224.1 1.8 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAG24702.1 - 0.011 15.6 1.5 0.035 14.0 1.1 2.1 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 OAG24702.1 - 0.066 13.5 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Effector protein HNH_5 PF14279.6 OAG24702.1 - 0.41 10.5 2.8 7.3 6.5 0.4 2.5 2 0 0 2 2 2 0 HNH endonuclease Dynamitin PF04912.14 OAG24703.1 - 0.1 11.9 0.2 0.12 11.7 0.2 1.0 1 0 0 1 1 1 0 Dynamitin Mucin PF01456.17 OAG24703.1 - 1.3 9.1 15.0 2.4 8.2 15.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_28 PF00295.17 OAG24704.1 - 8.3e-89 297.8 19.9 1e-88 297.5 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-C2H2 PF00096.26 OAG24705.1 - 0.0063 16.9 12.7 0.088 13.3 0.8 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG24705.1 - 9.1 7.4 12.4 7.1 7.8 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger PHO4 PF01384.20 OAG24706.1 - 2.5e-108 362.1 12.6 2.9e-108 361.9 12.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 OAG24706.1 - 0.022 15.1 1.5 0.09 13.2 0.0 2.8 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Glycophorin_A PF01102.18 OAG24706.1 - 0.039 14.2 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Glycophorin A bZIP_1 PF00170.21 OAG24708.1 - 2.2e-10 40.4 9.3 9.2e-10 38.5 9.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor MSA-2c PF12238.8 OAG24708.1 - 0.0019 18.2 2.7 0.0019 18.2 2.7 2.4 3 0 0 3 3 3 1 Merozoite surface antigen 2c bZIP_2 PF07716.15 OAG24708.1 - 0.024 14.7 10.6 0.12 12.5 6.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF1043 PF06295.12 OAG24708.1 - 0.039 14.0 2.9 0.095 12.7 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Pterin_4a PF01329.19 OAG24710.1 - 1e-25 89.7 0.2 1.4e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase OMP_b-brl_2 PF13568.6 OAG24711.1 - 0.13 12.3 0.0 0.54 10.2 0.0 1.8 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain CSN8_PSD8_EIF3K PF10075.9 OAG24712.1 - 1.4e-38 132.1 0.0 2.3e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 OAG24713.1 - 2e-46 158.2 0.0 6.2e-46 156.7 0.0 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain FA_desaturase PF00487.24 OAG24714.1 - 2.1e-15 57.3 20.2 3.8e-15 56.4 20.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG24714.1 - 9.9e-15 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OPT PF03169.15 OAG24718.1 - 8.8e-197 655.5 29.4 1.1e-196 655.2 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 OAG24718.1 - 0.031 14.3 0.8 0.12 12.4 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) BCS1_N PF08740.11 OAG24719.1 - 3.7e-45 154.2 0.0 5.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG24719.1 - 2.1e-18 67.0 0.0 4.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAG24719.1 - 6.4e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAG24719.1 - 0.0016 18.0 0.0 0.0056 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG24719.1 - 0.0019 18.6 0.1 0.011 16.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OAG24719.1 - 0.0042 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 OAG24719.1 - 0.0059 16.6 0.0 0.019 15.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 OAG24719.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OAG24719.1 - 0.016 14.9 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 OAG24719.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 OAG24719.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 OAG24719.1 - 0.039 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAG24719.1 - 0.048 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 OAG24719.1 - 0.053 13.9 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 OAG24719.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG24719.1 - 0.064 13.5 0.0 0.29 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG24719.1 - 0.071 13.3 0.0 0.46 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain CN_hydrolase PF00795.22 OAG24721.1 - 7e-37 127.2 0.0 8.8e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 OAG24721.1 - 0.055 13.5 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of band_7 EthD PF07110.11 OAG24722.1 - 2.7e-19 70.1 0.0 3.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG24722.1 - 0.00049 20.5 0.2 0.0049 17.3 0.2 2.1 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Rhodanese PF00581.20 OAG24722.1 - 0.096 13.2 0.0 3.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Rhodanese-like domain Paf67 PF10255.9 OAG24723.1 - 1.2e-160 535.0 0.1 1.4e-160 534.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAG24723.1 - 0.075 13.2 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2046 PF09755.9 OAG24724.1 - 0.00028 20.2 0.5 0.057 12.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 OAG24724.1 - 0.0012 18.5 1.8 0.0012 18.5 1.8 1.9 2 0 0 2 2 2 1 Septum formation initiator CENP-F_N PF10481.9 OAG24724.1 - 0.0017 18.1 1.8 0.0024 17.6 1.8 1.2 1 0 0 1 1 1 1 Cenp-F N-terminal domain CASP_C PF08172.12 OAG24724.1 - 0.0052 16.2 3.3 0.91 8.8 0.2 2.2 2 0 0 2 2 2 2 CASP C terminal SlyX PF04102.12 OAG24724.1 - 0.0085 16.7 3.6 0.38 11.4 1.3 2.5 2 0 0 2 2 2 1 SlyX DUF4140 PF13600.6 OAG24724.1 - 0.038 14.4 0.4 0.78 10.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) KIAA1430 PF13879.6 OAG24724.1 - 0.048 14.4 0.5 0.13 13.0 0.5 1.9 1 1 0 1 1 1 0 KIAA1430 homologue FlaC_arch PF05377.11 OAG24724.1 - 0.059 13.8 0.2 0.059 13.8 0.2 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC92 PF14916.6 OAG24724.1 - 0.064 13.0 1.0 1.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Cnn_1N PF07989.11 OAG24724.1 - 0.098 12.8 2.4 0.24 11.6 0.5 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 OAG24724.1 - 0.13 12.2 3.8 0.097 12.6 1.6 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FlxA PF14282.6 OAG24724.1 - 0.15 12.1 4.6 0.11 12.5 0.9 2.3 2 0 0 2 2 2 0 FlxA-like protein Snapin_Pallidin PF14712.6 OAG24724.1 - 0.17 12.3 2.4 1.4 9.4 0.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 OAG24724.1 - 0.18 12.3 2.9 0.25 11.9 0.3 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Phage_lysis PF03245.13 OAG24724.1 - 0.34 11.0 4.3 0.17 12.0 0.8 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein CENP-H PF05837.12 OAG24724.1 - 0.4 11.1 3.8 0.35 11.3 0.4 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4404 PF14357.6 OAG24724.1 - 0.88 10.2 3.4 12 6.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CLZ PF16526.5 OAG24724.1 - 0.92 9.9 5.8 4.6 7.7 1.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 OAG24724.1 - 0.99 9.6 15.2 0.21 11.8 10.1 2.2 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 OAG24724.1 - 2.8 8.1 9.6 1.2 9.3 4.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper T2SSM PF04612.12 OAG24724.1 - 3.8 7.5 6.2 13 5.8 1.3 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M DbpA PF03880.15 OAG24725.1 - 0.0021 18.0 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 OAG24725.1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX14 PF14880.6 OAG24727.1 - 5.9e-18 64.5 1.0 5.9e-18 64.5 1.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2458 PF10454.9 OAG24728.1 - 1e-52 178.3 0.0 1.6e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Actin PF00022.19 OAG24730.1 - 1.2e-24 86.7 0.0 3.1e-12 45.8 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OAG24730.1 - 0.0025 16.7 0.0 0.055 12.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Actin_micro PF17003.5 OAG24730.1 - 0.0072 15.5 0.0 0.03 13.5 0.1 1.8 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 OAG24730.1 - 0.082 13.3 0.0 0.28 11.6 0.0 2.0 1 1 0 1 1 1 0 Cell division protein FtsA zf-MYND PF01753.18 OAG24731.1 - 9.7e-11 41.6 11.5 2e-10 40.5 11.5 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG24731.1 - 0.027 14.8 9.1 0.055 13.8 9.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF4259 PF14078.6 OAG24731.1 - 0.16 12.7 0.2 0.24 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Glyoxalase PF00903.25 OAG24732.1 - 1.6e-18 67.1 0.0 3.8e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG24732.1 - 1.8e-10 41.1 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG24732.1 - 0.002 18.9 0.0 0.018 15.8 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG24732.1 - 0.028 14.6 0.0 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAG24732.1 - 0.1 12.6 0.1 6.1 6.8 0.0 2.4 3 0 0 3 3 3 0 Glyoxalase-like domain BTB PF00651.31 OAG24733.1 - 0.00043 20.5 0.0 0.0055 16.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2985 PF11204.8 OAG24734.1 - 1.9e-21 76.0 3.5 3.9e-21 75.0 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) MF_alpha_N PF05436.11 OAG24735.1 - 0.00097 19.0 0.4 0.0011 18.8 0.4 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus CP2 PF04516.15 OAG24737.1 - 1.7e-86 289.3 0.0 2.5e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 OAG24737.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Tektin family AKNA PF12443.8 OAG24737.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor CENP-K PF11802.8 OAG24738.1 - 6.7e-07 29.1 8.1 0.016 14.8 0.0 2.7 2 1 0 2 2 2 2 Centromere-associated protein K Trimer_CC PF08954.11 OAG24738.1 - 0.0004 19.9 2.5 0.0004 19.9 2.5 2.9 2 1 1 3 3 3 1 Trimerisation motif IF-2B PF01008.17 OAG24738.1 - 0.066 12.4 0.7 0.13 11.5 0.7 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family Laminin_II PF06009.12 OAG24738.1 - 0.15 12.1 9.7 0.81 9.7 2.5 2.4 2 0 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 OAG24738.1 - 2.6 8.1 16.2 0.08 12.9 0.8 4.3 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding LON_substr_bdg PF02190.16 OAG24738.1 - 2.8 7.7 5.5 0.39 10.6 0.5 2.1 2 1 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain TipAS PF07739.13 OAG24738.1 - 4.1 8.0 11.2 1.9 9.0 1.2 3.3 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain LemA PF04011.12 OAG24738.1 - 4.4 7.1 11.9 0.82 9.5 1.4 3.7 3 1 0 3 3 3 0 LemA family KH_1 PF00013.29 OAG24739.1 - 1.2e-41 140.3 5.2 2.1e-18 65.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG24739.1 - 2.2e-11 43.4 1.8 0.0039 17.0 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG24739.1 - 1.2e-05 25.3 4.1 0.27 11.3 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 OAG24739.1 - 9.3e-05 22.4 0.0 0.02 14.9 0.0 2.6 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_4 PF13083.6 OAG24739.1 - 0.00018 21.3 0.6 1.7 8.6 0.1 3.5 3 0 0 3 3 3 2 KH domain CRAL_TRIO PF00650.20 OAG24740.1 - 1.9e-36 125.2 0.0 3.4e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG24740.1 - 6e-08 32.8 0.1 1.3e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG24740.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Peptidase_C1 PF00112.23 OAG24740.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Papain family cysteine protease Exo_endo_phos PF03372.23 OAG24741.1 - 8e-22 77.9 0.8 9.9e-21 74.3 0.8 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OAG24741.1 - 7.1e-10 38.5 22.2 1.9e-07 30.7 8.5 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAG24741.1 - 1.3e-06 28.6 12.8 0.0037 17.6 5.0 2.9 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) DUF3921 PF13060.6 OAG24741.1 - 0.0033 17.4 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3921) LRR_1 PF00560.33 OAG24741.1 - 0.69 10.7 4.0 80 4.4 3.0 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OAG24741.1 - 8.3 6.8 10.3 1.2 9.3 1.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Methyltransf_25 PF13649.6 OAG24743.1 - 7.5e-12 45.8 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG24743.1 - 2.1e-10 41.1 0.0 3.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG24743.1 - 8.4e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG24743.1 - 1.9e-05 25.3 0.0 4.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG24743.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG24743.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 OAG24743.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 OAG24743.1 - 0.031 13.8 0.0 0.21 11.1 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase small domain 4HBT_2 PF13279.6 OAG24744.1 - 7.2e-33 113.7 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAG24744.1 - 0.097 13.0 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 Thioesterase superfamily Tox-SHH PF15652.6 OAG24745.1 - 0.1 13.6 0.4 0.1 13.6 0.4 2.9 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Baculo_PEP_C PF04513.12 OAG24745.1 - 0.52 10.3 5.9 9.8 6.2 0.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5446 PF17522.2 OAG24745.1 - 1.6 9.0 4.9 4.3 7.6 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DUF4228 PF14009.6 OAG24746.1 - 0.076 13.4 0.1 0.16 12.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) PBP1_TM PF14812.6 OAG24746.1 - 3.4 8.1 7.0 0.25 11.7 2.3 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GP67 PF17634.2 OAG24746.1 - 9 6.8 16.1 17 5.9 16.1 1.4 1 0 0 1 1 1 0 Gene product 67 DUF5532 PF17673.1 OAG24747.1 - 0.01 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5532) BTB PF00651.31 OAG24747.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Metalloenzyme PF01676.18 OAG24747.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily Mito_carr PF00153.27 OAG24748.1 - 2.6e-51 171.5 3.7 7.7e-21 73.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein MAM33 PF02330.16 OAG24749.1 - 1.9e-74 250.2 3.4 3.8e-74 249.2 3.4 1.5 1 1 0 1 1 1 1 Mitochondrial glycoprotein BTB PF00651.31 OAG24750.1 - 7.1e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HUN PF08729.10 OAG24752.1 - 1.4e-07 31.4 0.3 2.6e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Nop PF01798.18 OAG24753.1 - 3.4e-87 291.7 0.1 7e-87 290.7 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAG24753.1 - 1.4e-16 60.6 0.0 1.4e-16 60.6 0.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 OAG24753.1 - 0.46 10.5 22.5 0.7 10.0 22.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RP-C_C PF11800.8 OAG24753.1 - 0.81 9.7 10.2 0.45 10.6 0.4 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region RR_TM4-6 PF06459.12 OAG24753.1 - 5.5 6.7 10.8 8.4 6.1 10.3 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Cpn60_TCP1 PF00118.24 OAG24754.1 - 3.8e-166 553.5 1.7 4.3e-166 553.4 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_47 PF01532.20 OAG24755.1 - 4.2e-198 658.9 0.1 5e-198 658.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ETX_MTX2 PF03318.13 OAG24756.1 - 7.7e-07 29.1 6.6 1.4e-06 28.3 6.6 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 BB_PF PF18063.1 OAG24756.1 - 0.035 13.7 0.8 0.11 12.1 0.8 1.8 1 0 0 1 1 1 0 Beta barrel Pore-forming domain PTP_tm PF18861.1 OAG24757.1 - 0.0036 17.3 0.1 0.0079 16.2 0.0 1.5 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM51 PF15345.6 OAG24757.1 - 0.0044 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 OAG24757.1 - 0.0096 15.3 0.6 0.017 14.5 0.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 OAG24757.1 - 0.014 15.9 0.1 0.033 14.7 0.1 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J TrbC PF04956.13 OAG24757.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family Syndecan PF01034.20 OAG24757.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 OAG24757.1 - 0.17 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gram_pos_anchor PF00746.21 OAG24757.1 - 0.59 10.1 4.3 1.4 8.9 4.3 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif SET PF00856.28 OAG24759.1 - 1.1e-14 55.2 0.9 6.4e-14 52.7 0.3 2.3 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 OAG24759.1 - 0.042 14.1 1.0 0.085 13.2 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GRIM-19 PF06212.12 OAG24761.1 - 6e-23 81.3 0.1 2.3e-22 79.4 0.1 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 OAG24762.1 - 2.8e-27 95.7 0.1 2.6e-21 76.2 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase TLD PF07534.16 OAG24763.1 - 2e-26 92.9 0.0 6.3e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 TLD zf-RING_2 PF13639.6 OAG24764.1 - 3.9e-05 23.9 10.3 3.9e-05 23.9 10.3 2.2 2 0 0 2 2 2 1 Ring finger domain C1_1 PF00130.22 OAG24764.1 - 0.0012 18.7 5.6 0.003 17.4 5.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) BTB PF00651.31 OAG24764.1 - 0.0013 18.9 0.2 0.67 10.2 0.0 2.6 2 1 1 3 3 3 2 BTB/POZ domain zf-RING_4 PF14570.6 OAG24764.1 - 0.0073 16.1 7.9 0.013 15.2 7.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_2 PF13240.6 OAG24764.1 - 0.028 14.2 0.4 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PHD PF00628.29 OAG24764.1 - 0.048 13.6 10.6 0.1 12.5 10.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 OAG24764.1 - 0.12 12.5 7.6 0.78 9.8 7.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG24764.1 - 0.32 11.3 11.8 0.28 11.5 10.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 OAG24764.1 - 0.51 10.3 13.2 0.36 10.8 8.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 OAG24764.1 - 1.2 9.1 12.0 1 9.3 9.7 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG24764.1 - 1.5 8.7 12.0 1.4 8.9 10.4 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OAG24764.1 - 2.3 8.3 10.7 9.1 6.4 9.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon FANCL_C PF11793.8 OAG24764.1 - 5.1 7.3 12.2 0.56 10.4 7.5 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 OAG24765.1 - 3.4e-09 36.9 7.7 7.8e-09 35.7 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG24765.1 - 1.6e-05 25.1 6.3 3.4e-05 24.1 6.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG24765.1 - 0.00012 22.0 3.1 0.0003 20.8 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAG24765.1 - 0.00013 21.9 8.7 0.00027 20.8 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG24765.1 - 0.00019 21.4 5.6 0.00045 20.2 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG24765.1 - 0.00027 20.8 9.2 0.00053 19.8 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG24765.1 - 0.00027 20.6 4.0 0.00055 19.6 4.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 OAG24765.1 - 0.00045 20.3 7.0 0.001 19.2 7.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OAG24765.1 - 0.0018 18.1 9.4 0.0051 16.6 9.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG24765.1 - 0.0028 17.5 7.9 0.0052 16.7 7.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_4 PF15227.6 OAG24765.1 - 0.0038 17.3 4.9 0.027 14.6 4.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAG24765.1 - 0.0098 15.7 7.8 0.026 14.4 7.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG24765.1 - 0.038 13.6 4.9 0.082 12.5 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type BTB PF00651.31 OAG24765.1 - 0.11 12.8 0.0 4.1 7.7 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain GAGA PF09237.11 OAG24765.1 - 0.12 12.2 1.1 4 7.3 0.3 2.4 2 0 0 2 2 2 0 GAGA factor zf-HC5HC2H PF13771.6 OAG24765.1 - 0.15 12.4 5.1 0.3 11.4 5.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 OAG24765.1 - 0.18 11.6 6.7 0.33 10.8 6.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OAG24765.1 - 0.19 11.6 8.6 1.1 9.2 3.0 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 OAG24765.1 - 0.27 11.5 2.9 0.36 11.1 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon RINGv PF12906.7 OAG24765.1 - 0.36 11.0 7.3 0.84 9.8 7.3 1.7 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 OAG24765.1 - 0.76 9.7 7.7 0.13 12.2 2.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 OAG24765.1 - 1.4 9.3 5.1 12 6.3 1.2 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CEBP_ZZ PF16366.5 OAG24765.1 - 7.8 6.8 9.0 1.2 9.4 4.6 2.0 2 1 0 2 2 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PGDH_C PF16896.5 OAG24766.1 - 0.093 12.7 0.1 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Lactonase PF10282.9 OAG24769.1 - 6e-85 285.5 0.1 7.8e-85 285.1 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LVIVD PF08309.11 OAG24769.1 - 0.079 12.3 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 LVIVD repeat He_PIG PF05345.12 OAG24769.1 - 9.2 6.5 14.7 3.9 7.7 0.5 3.5 3 1 0 3 3 3 0 Putative Ig domain Big_9 PF17963.1 OAG24769.1 - 9.8 7.0 12.0 25 5.7 4.7 3.8 2 2 0 2 2 2 0 Bacterial Ig domain FAD_binding_4 PF01565.23 OAG24770.1 - 1.3e-21 76.8 7.0 2.5e-21 75.9 7.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG24770.1 - 2.2e-11 43.7 0.0 5.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Bac_surface_Ag PF01103.23 OAG24771.1 - 6.6e-48 163.9 1.6 8.4e-48 163.5 1.6 1.1 1 0 0 1 1 1 1 Surface antigen DUF1204 PF06721.11 OAG24771.1 - 0.25 10.8 0.9 0.4 10.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) UQ_con PF00179.26 OAG24772.1 - 1.1e-20 73.7 0.0 1.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.24 OAG24775.1 - 7.8e-107 357.9 16.5 9.2e-107 357.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG24775.1 - 3.4e-25 88.7 40.1 1.2e-22 80.3 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAG24775.1 - 0.0071 14.8 5.5 0.014 13.8 5.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Phage_holin_2_3 PF16080.5 OAG24775.1 - 6.2 6.7 6.7 1.5 8.7 0.3 3.0 3 0 0 3 3 3 0 Bacteriophage holin family HP1 BTB PF00651.31 OAG24776.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG24777.1 - 0.01 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain C1_2 PF03107.16 OAG24778.1 - 0.071 13.4 0.9 0.13 12.6 0.9 1.5 1 0 0 1 1 1 0 C1 domain DUF676 PF05057.14 OAG24779.1 - 7.9e-42 143.2 0.1 8.6e-28 97.3 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) DUF915 PF06028.11 OAG24779.1 - 0.072 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 OAG24779.1 - 0.15 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2457 PF10446.9 OAG24780.1 - 1.2 8.1 5.0 1.6 7.8 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) M20_dimer PF07687.14 OAG24781.1 - 1.3e-17 63.7 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAG24781.1 - 1.8e-06 27.8 0.0 1.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-CCHC_5 PF14787.6 OAG24782.1 - 0.066 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TB2_DP1_HVA22 PF03134.19 OAG24783.1 - 2.3e-20 72.3 4.4 4.1e-20 71.5 4.4 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nsp1_C PF05064.13 OAG24783.1 - 0.047 13.5 0.5 0.085 12.7 0.1 1.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region Mgm101p PF06420.12 OAG24784.1 - 8.4e-86 285.8 0.0 1.2e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF2486 PF10667.9 OAG24784.1 - 1.4 9.1 12.5 2 8.6 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) p450 PF00067.22 OAG24785.1 - 6.8e-77 259.2 0.0 8.4e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YL1 PF05764.13 OAG24786.1 - 0.0052 16.9 6.8 0.0083 16.3 6.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAG24786.1 - 1.2 7.4 5.0 1.7 6.8 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAG24786.1 - 3.3 7.0 8.9 5.3 6.4 8.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAG24786.1 - 6.5 4.8 13.1 9 4.4 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAG24786.1 - 8.2 5.6 10.8 14 4.9 10.8 1.3 1 0 0 1 1 1 0 BUD22 TPR_11 PF13414.6 OAG24787.1 - 0.0017 18.0 0.0 0.51 10.1 0.4 2.9 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 OAG24787.1 - 0.024 15.0 0.0 0.14 12.6 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG24787.1 - 0.12 13.0 1.3 3.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 OAG24788.1 - 4.3e-130 434.3 0.0 5.5e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 OAG24788.1 - 3.5e-07 30.5 0.5 2 9.4 0.0 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG24788.1 - 7.4e-07 29.6 0.1 0.005 17.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG24788.1 - 3e-06 26.9 1.7 0.037 14.1 0.2 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG24788.1 - 0.00066 19.4 0.6 0.61 10.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG24788.1 - 0.0026 18.3 0.3 29 5.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAG24788.1 - 0.0031 16.8 0.9 0.2 10.9 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG24788.1 - 0.0036 17.4 0.0 0.44 10.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG24788.1 - 0.0054 16.9 0.8 4.8 7.5 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAG24788.1 - 0.0061 16.5 1.4 5.6 7.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG24788.1 - 0.013 15.6 0.1 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG24788.1 - 0.062 13.6 3.4 26 5.2 0.1 4.2 3 2 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.19 OAG24789.1 - 1.2e-33 116.2 0.3 1.3e-33 116.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCC1_2 PF13540.6 OAG24790.1 - 1.7e-22 78.7 13.6 4.6e-06 26.3 0.8 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OAG24790.1 - 1.5e-20 73.6 10.7 1.2e-05 25.8 0.0 7.0 6 1 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_65N PF03636.15 OAG24791.1 - 4e-31 108.4 0.0 6.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 OAG24791.1 - 1.4e-29 103.2 1.8 1.7e-27 96.3 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.25 OAG24791.1 - 8.1e-06 26.0 0.1 3.3e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 F5/8 type C domain HET PF06985.11 OAG24792.1 - 4.7e-30 104.9 0.1 2.4e-29 102.6 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PadR PF03551.14 OAG24792.1 - 0.1 12.6 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Peptidase_M57 PF12388.8 OAG24793.1 - 0.09 12.4 0.1 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Amidohydro_1 PF01979.20 OAG24794.1 - 5e-77 259.5 0.0 5.9e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG24794.1 - 3.5e-08 33.4 0.9 2.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Actin PF00022.19 OAG24795.1 - 3.5e-21 75.3 0.0 1e-16 60.6 0.0 2.5 3 0 0 3 3 3 2 Actin cNMP_binding PF00027.29 OAG24796.1 - 7.6e-30 102.8 0.1 6.3e-16 58.2 0.0 5.2 4 1 1 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 OAG24796.1 - 2.1e-16 60.7 10.2 1.1e-15 58.4 6.2 3.6 3 1 0 3 3 3 1 Patatin-like phospholipase DUF2070 PF09843.9 OAG24796.1 - 6.8 4.9 8.2 10 4.3 8.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GDC-P PF02347.16 OAG24797.1 - 4.7e-176 585.8 0.0 1.4e-163 544.7 0.0 2.6 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAG24797.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG24797.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family F_bP_aldolase PF01116.20 OAG24800.1 - 1.1e-95 320.4 0.0 1.2e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF1806 PF08830.10 OAG24800.1 - 0.15 12.0 0.1 0.63 10.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1806) Ribosomal_L9_N PF01281.19 OAG24801.1 - 7e-09 35.1 0.0 1.9e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 OAG24801.1 - 0.0058 17.1 0.1 0.024 15.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain UCH PF00443.29 OAG24802.1 - 3.7e-37 128.2 0.0 1.2e-31 110.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG24802.1 - 4.9e-08 32.9 0.3 0.0049 16.5 0.3 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GFO_IDH_MocA PF01408.22 OAG24803.1 - 6.3e-11 43.2 0.0 1.4e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG24803.1 - 0.0006 19.8 0.0 0.0022 18.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IBN_N PF03810.19 OAG24805.1 - 1.2e-15 57.2 0.1 2.1e-12 46.8 0.0 3.0 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cse1 PF08506.10 OAG24805.1 - 1.5e-07 30.6 0.1 4.1e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 OAG24805.1 - 0.0069 16.5 2.8 1.2 9.1 0.0 4.3 4 0 0 4 4 4 1 Exportin 1-like protein RTP1_C1 PF10363.9 OAG24805.1 - 0.079 13.2 0.1 0.34 11.1 0.1 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OAG24805.1 - 0.083 13.2 0.1 6.3 7.4 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat SDA1 PF05285.12 OAG24805.1 - 4 6.8 11.1 6.2 6.1 11.1 1.2 1 0 0 1 1 1 0 SDA1 Pertussis_S1 PF02917.14 OAG24806.1 - 0.0018 18.1 0.1 0.0029 17.4 0.1 1.3 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 NRBF2 PF08961.10 OAG24806.1 - 0.0052 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator FAT PF02259.23 OAG24807.1 - 1.4e-116 389.5 4.9 1.4e-116 389.5 4.9 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAG24807.1 - 5.2e-72 242.7 0.1 1.1e-71 241.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAG24807.1 - 2.1e-66 222.8 1.1 1.2e-59 200.8 0.1 5.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAG24807.1 - 3.1e-43 146.2 0.0 3.1e-43 146.2 0.0 4.4 4 1 1 5 5 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OAG24807.1 - 6.9e-16 57.8 0.1 1.9e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OAG24807.1 - 2.8e-11 43.6 13.5 0.0091 16.4 0.0 9.9 8 2 3 11 11 10 3 HEAT repeats HEAT PF02985.22 OAG24807.1 - 6.7e-10 38.4 22.3 0.077 13.3 0.0 11.4 13 0 0 13 13 11 3 HEAT repeat HEAT_EZ PF13513.6 OAG24807.1 - 1e-06 29.1 20.0 0.049 14.2 0.0 10.5 10 2 3 13 13 11 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG24807.1 - 1.1e-06 29.1 0.0 4.3 8.0 0.0 6.3 7 0 0 7 7 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAG24807.1 - 2.4e-06 26.4 0.4 0.24 9.9 0.0 4.9 4 1 0 4 4 4 2 Adaptin N terminal region Tti2 PF10521.9 OAG24807.1 - 4.4e-06 26.4 0.5 0.37 10.3 0.1 4.3 2 1 1 4 4 4 2 Tti2 family Cnd1 PF12717.7 OAG24807.1 - 4.4e-06 26.8 1.7 0.82 9.7 0.0 5.8 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 OAG24807.1 - 0.00019 21.1 0.1 4.2 6.9 0.0 4.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) UME PF08064.13 OAG24807.1 - 0.00021 21.1 0.1 7.5 6.5 0.0 5.4 5 0 0 5 5 5 1 UME (NUC010) domain Sec7_N PF12783.7 OAG24807.1 - 0.0014 18.5 0.1 6.8 6.6 0.2 4.6 4 2 1 5 5 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_19 PF14559.6 OAG24807.1 - 0.0042 17.6 0.3 12 6.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CLASP_N PF12348.8 OAG24807.1 - 0.0064 16.1 0.4 49 3.4 0.0 5.0 4 1 0 4 4 4 0 CLASP N terminal TAF6_C PF07571.13 OAG24807.1 - 0.029 14.7 0.1 6.6 7.1 0.0 4.7 6 1 1 7 7 4 0 TAF6 C-terminal HEAT repeat domain DUF2115 PF09888.9 OAG24807.1 - 0.23 12.0 0.3 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TPR_1 PF00515.28 OAG24807.1 - 0.26 11.2 2.3 22 5.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG24807.1 - 0.31 11.7 7.4 1.8 9.3 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG24807.1 - 1.1 9.5 3.8 22 5.4 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAG24807.1 - 7.2 7.0 9.4 8 6.8 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SLAC1 PF03595.17 OAG24808.1 - 3.4e-82 276.3 42.4 4e-82 276.1 42.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4834 PF16118.5 OAG24808.1 - 0.49 11.4 0.0 0.49 11.4 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 OAG24809.1 - 6.2e-38 130.7 0.0 8.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24809.1 - 2.6e-24 85.9 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG24809.1 - 0.011 15.6 1.8 2.6 7.9 0.1 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1996 PF09362.10 OAG24810.1 - 3e-83 279.4 1.1 3.8e-83 279.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lipase_GDSL_2 PF13472.6 OAG24811.1 - 1.6e-21 77.5 0.5 2.4e-21 76.9 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG24811.1 - 9.2e-12 45.3 0.1 1.1e-11 45.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HET PF06985.11 OAG24812.1 - 2.9e-32 112.0 6.9 2.9e-30 105.5 6.9 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LigB PF02900.18 OAG24813.1 - 2.9e-33 115.1 0.0 3.4e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short_C2 PF13561.6 OAG24814.1 - 2.4e-07 30.5 0.0 3.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG24814.1 - 2.3e-06 27.2 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAG24814.1 - 0.063 12.4 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans_2 PF11951.8 OAG24815.1 - 9.4e-51 172.8 1.8 1.3e-50 172.4 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPAP3_C PF13877.6 OAG24815.1 - 0.18 12.4 0.1 0.47 11.0 0.1 1.7 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 FAD_binding_3 PF01494.19 OAG24816.1 - 1.1e-13 51.2 0.0 7e-08 32.1 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG24816.1 - 3.7e-06 26.4 0.0 1.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG24816.1 - 1.5e-05 25.1 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG24816.1 - 0.00011 22.7 0.0 0.083 13.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG24816.1 - 0.00064 19.4 0.0 0.00095 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG24816.1 - 0.0011 18.3 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG24816.1 - 0.0032 16.8 0.0 1 8.6 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG24816.1 - 0.0085 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG24816.1 - 0.06 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG24816.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAG24816.1 - 0.15 12.3 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_2 PF00891.18 OAG24817.1 - 2.2e-20 72.9 0.0 2.9e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG24817.1 - 0.00043 20.2 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain SAT PF16073.5 OAG24818.1 - 3.4e-33 115.4 0.0 4.7e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis CheW PF01584.19 OAG24818.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 CheW-like domain ketoacyl-synt PF00109.26 OAG24819.1 - 5.2e-78 262.1 0.0 1.1e-77 261.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG24819.1 - 2.6e-41 142.2 0.0 5.5e-41 141.1 0.0 1.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG24819.1 - 3.3e-32 111.0 1.5 8.2e-32 109.7 1.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAG24819.1 - 4.2e-10 39.8 2.5 8.6e-10 38.8 2.5 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 OAG24819.1 - 1.8e-08 34.0 0.0 4.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OAG24819.1 - 4.3e-08 33.6 0.0 1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OAG24819.1 - 3.7e-05 23.2 0.2 8.9e-05 22.0 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 OAG24819.1 - 0.054 14.1 0.0 0.17 12.5 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0242 PF06785.11 OAG24821.1 - 0.00023 21.3 4.5 0.00035 20.7 4.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Nsp1_C PF05064.13 OAG24821.1 - 0.0075 16.1 2.4 0.013 15.3 2.4 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region FAM76 PF16046.5 OAG24821.1 - 0.013 14.9 4.0 0.02 14.3 4.0 1.3 1 0 0 1 1 1 0 FAM76 protein DUF5094 PF17015.5 OAG24821.1 - 0.13 12.4 4.1 0.13 12.4 3.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) DAGK_cat PF00781.24 OAG24822.1 - 7.8e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BDV_P40 PF06407.11 OAG24822.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P40 protein TadE PF07811.12 OAG24823.1 - 0.35 11.2 2.4 0.6 10.4 2.4 1.3 1 0 0 1 1 1 0 TadE-like protein zf-CCHC PF00098.23 OAG24824.1 - 8.7e-10 38.2 11.3 5.1e-06 26.3 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle DNA_pol3_finger PF17657.1 OAG24825.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain Ifi-6-16 PF06140.13 OAG24826.1 - 4.6e-06 26.4 18.0 8.1e-06 25.7 18.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family G-gamma PF00631.22 OAG24827.1 - 0.11 12.5 0.3 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 GGL domain DUF16 PF01519.16 OAG24828.1 - 0.018 15.5 0.9 0.027 15.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Med21 PF11221.8 OAG24828.1 - 0.037 14.3 1.6 0.15 12.3 0.3 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DivIC PF04977.15 OAG24828.1 - 0.059 13.2 1.5 0.11 12.3 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator ECH_1 PF00378.20 OAG24829.1 - 7.2e-24 84.5 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG24829.1 - 1.1e-07 31.7 0.0 6e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Isochorismatase PF00857.20 OAG24830.1 - 4.9e-33 114.8 0.0 6.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family IMPa_N_2 PF18650.1 OAG24830.1 - 0.075 12.3 0.3 9.2 5.5 0.1 2.2 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Glyco_transf_4 PF13439.6 OAG24830.1 - 0.083 12.9 0.1 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 zf-RNPHF PF08080.12 OAG24830.1 - 0.18 11.8 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 RNPHF zinc finger Fungal_trans PF04082.18 OAG24832.1 - 2.8e-07 29.8 1.2 3.8e-07 29.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAG24833.1 - 7.1e-19 68.3 0.7 1.9e-10 40.5 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG24833.1 - 0.00018 21.7 0.1 0.00039 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG24833.1 - 0.0003 20.1 2.0 0.00039 19.7 0.2 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 OAG24833.1 - 0.0063 16.1 0.4 0.24 11.0 0.2 2.6 2 1 1 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 OAG24833.1 - 0.009 15.6 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG24833.1 - 0.012 16.2 0.1 0.028 15.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG24833.1 - 0.016 14.3 0.7 0.033 13.3 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAG24833.1 - 0.034 12.9 0.1 0.058 12.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 OAG24833.1 - 0.093 12.4 0.2 0.33 10.6 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAG24833.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAG24833.1 - 0.17 10.9 0.2 0.3 10.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 OAG24833.1 - 0.2 11.6 0.0 0.68 9.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 OAG24833.1 - 0.2 11.5 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B_3 PF13483.6 OAG24834.1 - 1.6e-06 28.1 0.1 4.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG24834.1 - 4.4e-06 26.4 0.0 6.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG24834.1 - 0.00016 21.7 0.1 0.00022 21.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily p450 PF00067.22 OAG24835.1 - 2.2e-66 224.5 0.0 2.9e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med9 PF07544.13 OAG24836.1 - 0.018 15.2 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1104 PF06518.11 OAG24836.1 - 0.038 14.3 0.2 0.062 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) SlyX PF04102.12 OAG24836.1 - 0.17 12.5 1.0 0.28 11.8 1.0 1.4 1 0 0 1 1 1 0 SlyX EthD PF07110.11 OAG24837.1 - 9.5e-11 42.7 0.1 1.2e-10 42.4 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG24837.1 - 0.0016 18.8 0.1 0.0026 18.2 0.1 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Putative_PNPOx PF01243.20 OAG24838.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Glycos_transf_2 PF00535.26 OAG24840.1 - 5.6e-35 120.7 0.0 6.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG24840.1 - 2.5e-12 47.2 0.0 3.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG24840.1 - 7.6e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 OAG24840.1 - 0.00013 21.6 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OAG24840.1 - 0.026 15.0 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hydrolase_like PF13242.6 OAG24841.1 - 2.4e-07 30.7 0.0 9.6e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG24841.1 - 0.0038 17.5 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG24841.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Surp PF01805.20 OAG24843.1 - 3.2e-11 43.0 0.0 7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Surp module DUF572 PF04502.13 OAG24843.1 - 6.8 6.2 11.3 11 5.5 6.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) TPR_19 PF14559.6 OAG24845.1 - 1.9e-10 41.1 3.3 9.5e-08 32.4 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OAG24845.1 - 0.001 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.6 OAG24845.1 - 0.001 19.7 2.5 0.2 12.3 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAG24845.1 - 0.0033 17.0 0.8 0.56 9.9 0.1 3.0 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 OAG24845.1 - 0.005 15.6 0.7 0.0067 15.2 0.1 1.5 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 OAG24845.1 - 0.0073 16.9 0.4 18 6.3 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG24845.1 - 0.016 15.2 1.0 58 4.2 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG24845.1 - 0.035 14.4 8.7 0.13 12.6 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG24845.1 - 0.048 14.5 8.2 4.4 8.4 0.1 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 OAG24846.1 - 1.3e-54 184.4 0.1 3.3e-54 183.1 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG24846.1 - 8.4e-48 162.0 0.1 8.3e-47 158.8 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG24846.1 - 3.5e-40 136.9 0.9 6.2e-40 136.1 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 OAG24846.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer2_4 PF13510.6 OAG24847.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF874 PF05917.11 OAG24849.1 - 3.9 6.4 11.7 1.5 7.8 8.0 1.8 2 0 0 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) FANCL_C PF11793.8 OAG24850.1 - 1.9e-06 27.9 2.7 3.3e-06 27.2 2.7 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 OAG24850.1 - 4.3e-06 26.8 7.2 8.9e-06 25.7 7.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAG24850.1 - 0.02 15.2 4.8 0.037 14.4 4.8 1.5 1 0 0 1 1 1 0 Ring finger domain TANGO2 PF05742.12 OAG24852.1 - 6.3e-75 252.5 0.0 7.1e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 FR47 PF08445.10 OAG24854.1 - 0.097 12.6 0.1 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein adh_short PF00106.25 OAG24855.1 - 1.6e-23 83.2 0.1 2.5e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24855.1 - 3.1e-18 66.2 0.2 4.7e-18 65.6 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24855.1 - 1e-08 35.3 0.3 2e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 OAG24855.1 - 0.0001 22.3 0.3 0.00017 21.6 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG24855.1 - 0.00039 20.0 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG24855.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sigma54_activ_2 PF14532.6 OAG24855.1 - 0.045 13.9 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Glyco_hydro_16 PF00722.21 OAG24858.1 - 3.6e-41 140.6 6.1 4.7e-41 140.2 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 OAG24859.1 - 3.8e-39 134.6 0.1 2.2e-22 79.7 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24859.1 - 1.9e-14 53.6 0.3 5e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG24859.1 - 0.048 12.4 0.1 0.086 11.6 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase APG6_N PF17675.1 OAG24860.1 - 7.7e-09 36.2 54.3 0.00016 22.2 4.5 4.4 1 1 2 3 3 3 2 Apg6 coiled-coil region IFT57 PF10498.9 OAG24860.1 - 4.7e-08 32.4 35.2 9.3e-08 31.4 35.2 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 OAG24860.1 - 2e-05 24.5 41.0 2.3e-05 24.3 27.9 2.3 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 OAG24860.1 - 5.3e-05 23.3 48.2 0.0006 19.9 19.4 4.4 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 OAG24860.1 - 0.00027 21.0 52.2 0.0029 17.6 10.8 4.7 2 1 3 5 5 4 2 Designed helical repeat protein 10 domain Cep57_CLD_2 PF14197.6 OAG24860.1 - 0.00033 20.7 41.1 0.014 15.5 5.4 5.7 3 1 0 4 4 4 1 Centrosome localisation domain of PPC89 ZapB PF06005.12 OAG24860.1 - 0.00046 20.6 44.0 0.13 12.8 4.4 5.5 4 1 1 5 5 5 2 Cell division protein ZapB FPP PF05911.11 OAG24860.1 - 0.00052 18.3 36.0 0.00052 18.3 36.0 2.4 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil GAS PF13851.6 OAG24860.1 - 0.00058 19.3 48.5 0.076 12.4 9.4 3.6 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 OAG24860.1 - 0.00058 20.1 32.8 0.12 12.6 8.9 3.4 1 1 1 3 3 3 2 Fibrinogen alpha/beta chain family Filament PF00038.21 OAG24860.1 - 0.0018 17.9 42.3 0.05 13.2 5.3 4.1 1 1 2 4 4 4 3 Intermediate filament protein TMF_TATA_bd PF12325.8 OAG24860.1 - 0.0037 17.5 39.9 0.31 11.3 10.5 4.4 2 1 2 4 4 4 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAG24860.1 - 0.0049 16.8 50.9 0.047 13.7 6.9 5.3 2 1 3 5 5 5 2 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 OAG24860.1 - 0.0064 16.6 10.7 0.0064 16.6 10.7 4.6 2 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 OAG24860.1 - 0.0071 16.4 33.4 0.99 9.5 3.9 4.7 2 1 2 4 4 4 2 TolA binding protein trimerisation DivIVA PF05103.13 OAG24860.1 - 0.0072 16.4 9.1 0.0072 16.4 9.1 4.1 1 1 3 4 4 4 1 DivIVA protein Exonuc_VII_L PF02601.15 OAG24860.1 - 0.0087 15.7 26.9 2.2e+03 -2.1 26.9 3.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 OAG24860.1 - 0.015 15.2 10.4 0.015 15.2 10.4 5.0 3 1 1 5 5 2 0 FlxA-like protein KxDL PF10241.9 OAG24860.1 - 0.016 15.4 30.0 0.027 14.8 2.0 4.6 3 2 1 4 4 4 0 Uncharacterized conserved protein Lebercilin PF15619.6 OAG24860.1 - 0.021 14.5 51.2 0.14 11.8 6.1 3.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Suppressor_APC PF11414.8 OAG24860.1 - 0.026 14.6 0.3 0.026 14.6 0.3 3.6 2 1 2 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein DUF1664 PF07889.12 OAG24860.1 - 0.026 14.5 26.5 0.046 13.8 4.1 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OAG24860.1 - 0.028 14.7 24.1 0.3 11.4 0.9 4.8 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) TACC_C PF05010.14 OAG24860.1 - 0.037 13.8 36.1 0.59 9.9 4.2 4.2 2 1 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tropomyosin PF00261.20 OAG24860.1 - 0.042 13.2 55.7 0.031 13.6 16.7 3.6 2 1 1 4 4 3 0 Tropomyosin SHE3 PF17078.5 OAG24860.1 - 0.049 13.3 42.4 0.31 10.7 31.1 3.0 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 TSC22 PF01166.18 OAG24860.1 - 0.049 13.9 19.3 0.32 11.3 1.6 4.6 4 1 0 4 4 4 0 TSC-22/dip/bun family Prefoldin PF02996.17 OAG24860.1 - 0.076 12.9 37.5 1.1 9.2 4.2 5.1 4 1 1 5 5 5 0 Prefoldin subunit MAD PF05557.13 OAG24860.1 - 0.082 11.3 47.3 0.0057 15.1 32.8 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein FliJ PF02050.16 OAG24860.1 - 0.094 12.9 29.9 2.8 8.2 10.4 4.3 2 1 1 3 3 3 0 Flagellar FliJ protein Leu_zip PF15294.6 OAG24860.1 - 0.2 11.1 47.2 0.53 9.8 11.4 3.2 1 1 2 3 3 3 0 Leucine zipper Cnn_1N PF07989.11 OAG24860.1 - 0.21 11.8 34.0 0.65 10.2 13.3 4.9 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 OAG24860.1 - 0.24 11.4 50.4 0.49 10.4 20.3 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 OAG24860.1 - 0.25 11.7 25.4 0.37 11.2 1.7 5.0 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 OAG24860.1 - 0.29 9.3 38.8 0.13 10.5 16.5 3.2 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 OAG24860.1 - 0.33 11.4 20.4 0.67 10.5 1.9 4.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HOOK PF05622.12 OAG24860.1 - 0.35 8.9 48.9 1.1 7.4 31.3 2.6 1 1 1 3 3 3 0 HOOK protein MscS_porin PF12795.7 OAG24860.1 - 0.37 10.3 54.3 0.2 11.2 14.3 3.8 2 1 2 4 4 3 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 OAG24860.1 - 0.41 10.7 29.5 1.3 9.0 1.7 3.9 2 1 0 3 3 3 0 Laminin Domain II DUF4200 PF13863.6 OAG24860.1 - 0.57 10.6 47.5 0.27 11.6 10.5 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 OAG24860.1 - 0.65 8.8 50.1 1.3 7.9 31.5 3.2 1 1 0 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.14 OAG24860.1 - 0.7 9.5 38.9 0.088 12.5 3.6 3.6 1 1 2 3 3 3 0 Laminin Domain I ABC_tran_CTD PF16326.5 OAG24860.1 - 0.86 9.9 42.1 0.58 10.4 6.1 5.2 3 2 2 5 5 5 0 ABC transporter C-terminal domain GIT_CC PF16559.5 OAG24860.1 - 1 9.3 19.6 0.96 9.4 3.6 3.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DLP_helical PF18709.1 OAG24860.1 - 1.1 8.4 29.6 0.092 11.9 1.1 4.0 2 1 1 4 4 4 0 Dynamin-like helical domain YabA PF06156.13 OAG24860.1 - 1.1 9.9 36.9 3.4 8.3 4.4 4.6 1 1 2 4 4 4 0 Initiation control protein YabA DMPK_coil PF08826.10 OAG24860.1 - 1.3 9.2 36.4 0.39 10.9 4.9 5.6 4 2 1 5 5 5 0 DMPK coiled coil domain like LXG PF04740.12 OAG24860.1 - 1.3 8.7 32.1 2.9 7.5 2.7 3.9 1 1 3 4 4 4 0 LXG domain of WXG superfamily KELK PF15796.5 OAG24860.1 - 1.3 9.5 44.2 0.23 12.0 4.0 4.4 3 1 0 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Golgin_A5 PF09787.9 OAG24860.1 - 1.5 8.2 51.0 0.97 8.8 20.8 3.2 1 1 3 4 4 4 0 Golgin subfamily A member 5 P4Ha_N PF08336.11 OAG24860.1 - 1.6 8.8 23.9 1.1 9.3 0.8 4.1 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 OAG24860.1 - 1.8 9.0 53.7 0.078 13.4 16.7 3.9 1 1 3 4 4 4 0 Fez1 MIS13 PF08202.11 OAG24860.1 - 1.9 7.7 41.2 0.38 10.0 16.0 2.6 1 1 1 2 2 2 0 Mis12-Mtw1 protein family FH2 PF02181.23 OAG24860.1 - 2.5 7.1 33.0 0.3 10.1 6.0 4.1 1 1 4 5 5 5 0 Formin Homology 2 Domain DUF812 PF05667.11 OAG24860.1 - 2.6 6.8 56.3 0.01 14.7 21.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF812) LPP PF04728.13 OAG24860.1 - 2.6 8.5 31.0 2 8.8 0.2 6.3 4 2 2 6 6 6 0 Lipoprotein leucine-zipper DUF4140 PF13600.6 OAG24860.1 - 2.7 8.5 38.2 2.1 8.8 0.6 5.7 3 1 2 5 5 4 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 OAG24860.1 - 3.3 8.4 27.5 2.2 8.9 3.0 5.7 2 1 3 5 5 5 0 SlyX Phage_GP20 PF06810.11 OAG24860.1 - 3.4 7.5 48.0 19 5.0 9.7 4.0 1 1 0 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 OAG24860.1 - 3.9 7.5 54.9 0.28 11.3 17.6 4.2 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 OAG24860.1 - 4.1 7.1 45.4 1.4 8.7 3.1 4.8 3 1 2 5 5 4 0 Domain of unknown function (DUF4201) Swi5 PF07061.11 OAG24860.1 - 6.1 7.0 36.0 0.88 9.7 1.3 5.4 2 1 3 5 5 5 0 Swi5 Prefoldin_2 PF01920.20 OAG24860.1 - 6.9 6.7 41.0 6.6 6.7 3.0 5.4 2 1 2 4 4 4 0 Prefoldin subunit AIP3 PF03915.13 OAG24860.1 - 7 5.6 37.2 72 2.3 36.0 2.3 1 1 0 1 1 1 0 Actin interacting protein 3 MtrB PF05440.12 OAG24860.1 - 7.5 7.0 5.1 16 6.0 0.1 3.4 3 1 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase subunit B HAP1_N PF04849.13 OAG24860.1 - 8.5 5.5 43.8 5.2 6.2 3.3 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ApoO PF09769.9 OAG24860.1 - 8.9 6.3 11.0 14 5.7 1.6 3.4 2 1 1 3 3 3 0 Apolipoprotein O Uso1_p115_C PF04871.13 OAG24860.1 - 9.8 6.6 59.0 1.6 9.1 11.8 4.7 1 1 3 4 4 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region RAC_head PF16717.5 OAG24861.1 - 1.6e-30 105.9 6.2 1.6e-30 105.9 6.2 3.7 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 OAG24861.1 - 5.5e-20 71.3 0.5 2.4e-19 69.2 0.5 2.2 1 0 0 1 1 1 1 DnaJ domain GHBP PF12772.7 OAG24861.1 - 0.028 14.0 8.8 0.06 12.9 8.8 1.5 1 0 0 1 1 1 0 Growth hormone receptor binding UPF0565 PF10561.9 OAG24861.1 - 1 8.5 4.1 1.6 7.9 4.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 LMBR1 PF04791.16 OAG24861.1 - 2.4 7.0 7.4 2.8 6.7 7.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Usp PF00582.26 OAG24862.1 - 1.5e-19 70.9 0.0 2.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family ABA_GPCR PF12430.8 OAG24863.1 - 2.6e-57 193.5 1.5 2.6e-57 193.5 1.5 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAG24863.1 - 1e-22 80.0 2.0 1.7e-22 79.3 0.0 2.4 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal DprA_WH PF17782.1 OAG24863.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 DprA winged helix domain Herpes_LMP1 PF05297.11 OAG24864.1 - 0.69 9.1 2.2 0.71 9.0 2.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Rod_cone_degen PF15201.6 OAG24864.1 - 1.1 9.4 3.0 1 9.5 2.2 1.4 1 1 0 1 1 1 0 Progressive rod-cone degeneration Ank_2 PF12796.7 OAG24865.1 - 6.5e-20 71.5 0.1 4.4e-12 46.4 0.0 5.5 5 2 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG24865.1 - 2.2e-18 64.4 2.6 0.0036 17.7 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OAG24865.1 - 1.7e-17 63.5 0.6 7.3e-07 29.6 0.0 7.7 4 2 5 9 9 9 3 Ankyrin repeats (many copies) Clr5 PF14420.6 OAG24865.1 - 8.9e-17 61.1 0.2 2.3e-16 59.8 0.2 1.8 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 OAG24865.1 - 3.9e-09 36.5 3.3 0.0012 19.2 0.3 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG24865.1 - 5.3e-05 23.4 1.6 0.52 10.7 0.0 6.1 5 1 3 8 8 8 1 Ankyrin repeats (many copies) TauD PF02668.16 OAG24866.1 - 9.5e-28 97.7 1.3 1.8e-27 96.8 1.3 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UreD PF01774.17 OAG24866.1 - 0.0049 16.8 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein TauD PF02668.16 OAG24867.1 - 4.9e-31 108.5 0.3 6.9e-31 108.0 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.7 OAG24868.1 - 3.7e-16 60.4 2.4 4.4e-16 60.1 2.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG24868.1 - 3e-14 53.3 0.1 4.5e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG24868.1 - 1.9e-13 50.2 0.1 2.4e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG24868.1 - 2.5e-07 31.0 0.1 5.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 OAG24868.1 - 4.4e-05 23.2 0.0 6.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 OAG24868.1 - 5.5e-05 23.1 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.16 OAG24868.1 - 0.00011 22.1 0.6 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 OAG24868.1 - 0.00014 20.6 0.0 0.00017 20.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 OAG24868.1 - 0.0003 20.5 0.3 0.00079 19.1 0.1 1.6 2 0 0 2 2 2 1 Putative esterase Peptidase_S28 PF05577.12 OAG24868.1 - 0.0045 15.8 0.0 0.0062 15.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PGAP1 PF07819.13 OAG24868.1 - 0.011 15.4 0.5 0.016 14.9 0.2 1.4 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 OAG24868.1 - 0.025 14.3 0.0 0.054 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 OAG24868.1 - 0.089 12.7 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase PF00151.19 OAG24868.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipase Abhydrolase_8 PF06259.12 OAG24868.1 - 0.13 11.9 0.8 0.28 10.8 0.2 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase DUF1057 PF06342.12 OAG24868.1 - 0.15 11.1 0.0 0.34 9.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Palm_thioest PF02089.15 OAG24868.1 - 0.22 11.3 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Transp_cyt_pur PF02133.15 OAG24870.1 - 1.1e-101 340.8 37.7 1.3e-101 340.6 37.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Acetyltransf_3 PF13302.7 OAG24871.1 - 4.4e-14 53.3 0.0 5.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG24871.1 - 5.6e-05 23.4 0.1 0.00011 22.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAG24871.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG24871.1 - 0.072 13.1 0.2 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein HD_5 PF13487.6 OAG24871.1 - 0.17 12.1 0.1 1.8 8.9 0.0 2.4 2 1 0 2 2 2 0 HD domain DUF3425 PF11905.8 OAG24873.1 - 4.8e-18 65.3 0.3 1.1e-17 64.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Poty_coat PF00767.18 OAG24873.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Potyvirus coat protein Aldo_ket_red PF00248.21 OAG24874.1 - 9.1e-58 195.8 0.1 1.1e-57 195.5 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Piwi PF02171.17 OAG24875.1 - 4.1e-69 233.1 0.0 6.4e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG24875.1 - 4.9e-17 62.8 0.0 9.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG24875.1 - 3.9e-16 58.4 0.4 8.5e-16 57.4 0.4 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAG24875.1 - 2.6e-10 40.4 0.0 6.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 OAG24875.1 - 2.5e-09 37.1 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 OAG24875.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute DUF281 PF03436.13 OAG24876.1 - 0.1 13.0 0.2 0.25 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF281) HET PF06985.11 OAG24877.1 - 4.7e-37 127.6 0.1 8.2e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG24878.1 - 2.1e-39 135.4 11.3 1.4e-35 122.8 5.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG24878.1 - 0.0062 15.9 1.9 0.0072 15.7 0.2 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FMO-like PF00743.19 OAG24879.1 - 7.5e-32 110.4 0.2 7.4e-23 80.8 0.1 2.8 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG24879.1 - 8.2e-19 68.0 0.0 4.9e-18 65.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG24879.1 - 4.8e-15 55.6 0.0 6.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG24879.1 - 1.2e-10 41.6 5.2 0.00019 21.1 3.8 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG24879.1 - 5.3e-10 39.4 0.0 1.6e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG24879.1 - 3e-06 26.8 1.0 0.0097 15.2 0.3 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG24879.1 - 8.5e-06 25.8 4.8 0.032 14.2 1.2 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG24879.1 - 9.8e-06 26.0 0.2 0.0018 18.8 1.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG24879.1 - 8.1e-05 21.9 1.8 0.00044 19.4 0.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG24879.1 - 8.3e-05 21.4 1.2 0.0015 17.3 1.9 2.1 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 OAG24879.1 - 8.5e-05 21.8 1.1 0.0045 16.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG24879.1 - 0.00019 20.7 0.5 0.00033 20.0 0.5 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG24879.1 - 0.00073 18.9 0.6 0.0013 18.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAG24879.1 - 0.00074 18.7 3.6 0.0015 17.7 2.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG24879.1 - 0.002 17.6 1.8 0.0038 16.6 1.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG24879.1 - 0.0057 16.7 0.1 0.015 15.4 0.1 1.6 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAG24879.1 - 0.015 14.6 0.7 0.028 13.7 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG24879.1 - 0.031 14.2 0.5 0.056 13.3 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG24879.1 - 0.034 14.3 0.1 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OAG24879.1 - 0.044 13.4 0.1 0.091 12.3 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 OAG24879.1 - 0.16 11.6 1.8 0.33 10.6 0.9 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TauD PF02668.16 OAG24880.1 - 2.3e-62 211.2 0.2 3e-62 210.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidohydro_2 PF04909.14 OAG24881.1 - 2.3e-40 139.2 0.5 2.9e-40 138.9 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 OAG24882.1 - 0.00044 19.3 2.6 0.00068 18.7 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAG24883.1 - 4.2e-08 33.2 0.6 4.2e-08 33.2 0.6 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG24883.1 - 9.7e-08 31.9 0.0 8.5e-07 28.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polyketide_cyc2 PF10604.9 OAG24884.1 - 1.6e-10 41.4 0.0 1.8e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG24884.1 - 0.12 12.5 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF155 PF02582.14 OAG24885.1 - 0.26 11.3 1.0 0.86 9.7 0.9 1.8 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 NmrA PF05368.13 OAG24886.1 - 4.2e-16 59.2 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG24886.1 - 7.1e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG24886.1 - 1.9e-08 34.1 0.0 0.00027 20.5 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG24886.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 OAG24886.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 OAG24886.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Polyketide_cyc2 PF10604.9 OAG24887.1 - 2.5e-10 40.8 0.0 2.9e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.25 OAG24888.1 - 1.4e-12 47.5 0.1 2.6e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24888.1 - 1.3e-07 31.4 0.0 9.2e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24888.1 - 1.4e-05 25.1 0.1 0.00042 20.3 0.0 2.2 2 0 0 2 2 2 1 KR domain CinA_KH PF18146.1 OAG24888.1 - 0.099 12.8 0.2 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Questin_oxidase PF14027.6 OAG24889.1 - 1.8e-66 225.1 3.9 2.2e-64 218.2 3.9 2.3 1 1 0 1 1 1 1 Questin oxidase-like NADH5_C PF06455.11 OAG24889.1 - 0.044 13.4 0.1 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Cwf_Cwc_15 PF04889.12 OAG24890.1 - 0.013 15.2 5.2 0.016 14.9 5.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 OAG24891.1 - 4.1 6.1 4.1 4.6 5.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OAG24892.1 - 0.34 9.4 6.8 0.45 9.0 6.8 1.2 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 OAG24892.1 - 7.3 6.4 22.5 8.7 6.2 22.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2470 PF10615.9 OAG24894.1 - 9e-21 74.3 1.4 1.3e-20 73.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 OAG24894.1 - 0.0076 16.6 1.4 0.013 15.8 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Corona_I PF03187.14 OAG24895.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Corona nucleocapsid I protein MFS_1 PF07690.16 OAG24896.1 - 1.3e-20 73.7 64.0 1.3e-19 70.3 62.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily YtpI PF14007.6 OAG24896.1 - 0.24 11.5 2.3 2.4 8.4 0.3 3.2 3 0 0 3 3 3 0 YtpI-like protein HET PF06985.11 OAG24898.1 - 0.00044 20.6 0.0 0.024 15.0 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG24899.1 - 5e-28 97.9 0.9 6.4e-28 97.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24899.1 - 4.1e-22 78.9 0.6 5.1e-22 78.6 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24899.1 - 3.4e-10 40.1 0.9 3e-08 33.8 0.5 2.1 1 1 1 2 2 2 2 KR domain NAD_binding_10 PF13460.6 OAG24899.1 - 1.3e-06 28.5 0.6 6.9e-06 26.1 0.4 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG24899.1 - 0.00062 19.3 0.1 0.0014 18.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fucose_iso_N2 PF07882.12 OAG24902.1 - 0.053 13.1 0.2 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Arnt_C PF18583.1 OAG24902.1 - 0.086 12.5 0.5 0.29 10.8 0.1 1.9 1 1 1 2 2 2 0 Aminoarabinose transferase C-terminal domain Zn_clus PF00172.18 OAG24903.1 - 6.6e-07 29.3 13.1 1.2e-06 28.5 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAG24903.1 - 0.28 11.0 11.1 2.6 7.9 3.3 2.6 1 1 1 2 2 2 0 Integrin plexin domain adh_short PF00106.25 OAG24904.1 - 3.6e-25 88.6 0.0 5.9e-25 87.9 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24904.1 - 1e-16 61.3 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24904.1 - 1.4e-08 34.9 0.0 8e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 KR domain AIRC PF00731.20 OAG24904.1 - 0.0087 15.7 0.2 0.35 10.4 0.1 2.4 2 0 0 2 2 2 1 AIR carboxylase RasGEF PF00617.19 OAG24905.1 - 2.9e-42 144.8 0.0 5.5e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG24905.1 - 4e-15 55.9 0.2 1.4e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 OAG24905.1 - 2.8e-05 23.8 0.0 0.0002 21.0 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 OAG24905.1 - 0.011 16.1 0.0 0.052 13.9 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 OAG24905.1 - 0.035 14.2 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.13 OAG24905.1 - 0.047 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 OAG24905.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG24905.1 - 0.069 13.7 0.1 1.3 9.6 0.0 2.7 3 0 0 3 3 2 0 ABC transporter DUF1512 PF07431.12 OAG24905.1 - 0.082 11.9 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) AAA_33 PF13671.6 OAG24905.1 - 0.084 13.0 0.0 0.33 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG24905.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 OAG24905.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OAG24905.1 - 0.14 12.0 0.3 5.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OAG24905.1 - 9.5 6.8 6.5 15 6.1 0.0 3.7 4 1 0 4 4 4 0 AAA domain p450 PF00067.22 OAG24906.1 - 1e-59 202.5 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 OAG24907.1 - 3.2e-16 59.6 0.0 6.5e-16 58.6 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG24907.1 - 1.3e-12 48.3 0.0 4.9e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG24907.1 - 7.4e-10 39.3 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG24907.1 - 2.8e-09 36.9 0.0 4e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG24907.1 - 1.8e-06 28.6 0.0 1.3e-05 25.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG24907.1 - 9e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAG24907.1 - 0.0025 17.4 0.0 0.0083 15.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 OAG24907.1 - 0.0049 16.3 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OAG24907.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OAG24907.1 - 0.026 13.9 0.0 0.17 11.2 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG24907.1 - 0.038 13.3 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OAG24907.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 OAG24907.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 OAG24907.1 - 0.17 11.1 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain SSXRD PF09514.10 OAG24907.1 - 4.5 6.9 5.5 0.9 9.2 0.1 2.3 2 0 0 2 2 2 0 SSXRD motif FAD_binding_3 PF01494.19 OAG24908.1 - 9.7e-18 64.5 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG24908.1 - 1e-08 35.3 0.5 2.3e-08 34.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG24908.1 - 6.1e-08 32.6 1.2 1e-07 31.9 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG24908.1 - 4.6e-06 26.1 0.3 9.1e-06 25.1 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG24908.1 - 2.3e-05 23.7 1.9 0.00062 19.0 1.4 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG24908.1 - 7.5e-05 23.2 0.3 0.00049 20.6 0.3 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG24908.1 - 0.00015 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG24908.1 - 0.00083 18.8 0.1 0.0041 16.5 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG24908.1 - 0.0017 17.4 0.1 0.0023 17.1 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAG24908.1 - 0.0068 15.5 1.3 0.011 14.8 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG24908.1 - 0.012 14.3 0.7 0.02 13.6 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG24908.1 - 0.015 14.6 0.2 0.035 13.4 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 OAG24908.1 - 0.015 15.1 0.4 0.032 14.1 0.4 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 OAG24908.1 - 0.034 14.0 1.0 0.071 13.0 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAG24908.1 - 0.1 11.8 1.0 0.28 10.4 0.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG24908.1 - 0.22 10.3 1.0 1.2 7.9 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Cupin_2 PF07883.11 OAG24909.1 - 3.4e-07 29.9 0.0 6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 OAG24909.1 - 0.0044 16.7 0.1 0.0071 16.0 0.1 1.3 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase KR PF08659.10 OAG24910.1 - 3e-07 30.5 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG24910.1 - 4.5e-06 26.3 0.0 0.0035 16.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 OAG24910.1 - 0.014 14.9 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG24910.1 - 0.026 13.7 0.0 0.09 11.9 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein FAD_binding_4 PF01565.23 OAG24911.1 - 6.9e-27 93.9 0.1 1.2e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pept_S41_N PF18294.1 OAG24912.1 - 0.17 11.9 1.6 0.33 11.0 1.6 1.4 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain UbiA PF01040.18 OAG24913.1 - 1.4e-37 129.4 24.3 1.4e-37 129.4 24.3 1.4 1 1 1 2 2 2 1 UbiA prenyltransferase family DAP10 PF07213.11 OAG24913.1 - 0.32 11.0 2.5 2.4 8.2 0.1 2.9 3 0 0 3 3 3 0 DAP10 membrane protein FAD_binding_4 PF01565.23 OAG24914.1 - 1.3e-27 96.3 0.2 3.2e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG24914.1 - 0.00013 22.0 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Vac14_Fig4_bd PF11916.8 OAG24914.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding HET PF06985.11 OAG24915.1 - 2e-28 99.6 3.6 3.7e-28 98.7 3.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UFC1 PF08694.11 OAG24915.1 - 1.3 8.7 4.6 14 5.3 0.4 3.0 3 0 0 3 3 3 0 Ubiquitin-fold modifier-conjugating enzyme 1 LSR PF05624.14 OAG24918.1 - 1.6 8.8 28.1 2.4 8.2 28.1 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Corona_S2 PF01601.16 OAG24918.1 - 2.2 6.7 12.1 3 6.2 12.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Fungal_trans PF04082.18 OAG24919.1 - 1.1e-10 41.0 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG24919.1 - 1.9e-05 24.7 9.9 3.7e-05 23.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5316 PF17247.2 OAG24921.1 - 0.55 10.3 7.4 0.11 12.6 2.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5316) TRP PF06011.12 OAG24922.1 - 4.3e-107 358.5 23.1 5.9e-107 358.0 23.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG24922.1 - 3.3e-37 127.9 0.0 6.7e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 ML-like domain DUF4267 PF14087.6 OAG24923.1 - 1.6e-16 60.3 3.8 2.3e-16 59.8 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.25 OAG24924.1 - 3.1e-67 226.7 0.0 3.6e-66 223.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 OAG24924.1 - 2.2e-36 124.1 0.1 5.2e-36 122.9 0.1 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 OAG24924.1 - 2.6e-31 108.9 0.0 5.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG24924.1 - 0.0012 18.2 0.4 0.0028 17.1 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG24924.1 - 0.016 15.2 0.7 0.068 13.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG24924.1 - 0.021 14.4 1.3 0.077 12.6 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase zf-C2H2 PF00096.26 OAG24927.1 - 2.5e-12 46.5 10.9 4.7e-06 26.8 0.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG24927.1 - 2e-06 28.1 8.9 0.00037 21.1 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG24927.1 - 2.1e-05 24.8 2.3 2.1e-05 24.8 2.3 3.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAG24927.1 - 3.4e-05 23.5 7.4 0.0071 16.1 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 OAG24927.1 - 0.012 16.1 8.5 1.1 9.8 1.0 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 OAG24927.1 - 0.014 15.7 0.1 0.014 15.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG24927.1 - 0.39 11.2 0.2 0.39 11.2 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GFA PF04828.14 OAG24928.1 - 0.00034 20.9 1.3 0.00037 20.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 OAG24928.1 - 0.01 15.5 0.7 0.01 15.5 0.7 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain 4HBT PF03061.22 OAG24929.1 - 0.048 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily NAD_binding_10 PF13460.6 OAG24930.1 - 2.3e-09 37.4 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG24930.1 - 3e-09 36.8 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Fe-S_biosyn PF01521.20 OAG24931.1 - 5.7e-17 61.9 0.0 7.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-3CxxC_2 PF17180.4 OAG24931.1 - 0.052 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding domain zf-C2HC_2 PF13913.6 OAG24931.1 - 1.3 9.0 4.9 1.3 9.0 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Dabb PF07876.12 OAG24932.1 - 3e-23 82.2 0.0 3.5e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2407_C PF13373.6 OAG24933.1 - 1e-38 132.7 0.0 1.8e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAG24933.1 - 5.2e-31 107.3 0.0 1.5e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG24933.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family FSA_C PF10479.9 OAG24933.1 - 2.8 6.0 6.0 3.6 5.6 6.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Arginase PF00491.21 OAG24934.1 - 7.9e-92 307.7 0.0 1e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG24934.1 - 0.035 14.3 0.0 0.065 13.5 0.0 1.4 1 1 0 1 1 1 0 UPF0489 domain MatE PF01554.18 OAG24935.1 - 3.5e-61 205.6 19.5 5.7e-31 107.3 6.3 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG24935.1 - 4.4e-07 30.1 5.4 4.4e-07 30.1 5.4 3.9 3 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Glyco_hydro_76 PF03663.14 OAG24936.1 - 6.9e-35 121.2 12.2 8.1e-35 121.0 12.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HSP9_HSP12 PF04119.12 OAG24937.1 - 6.9e-26 90.4 1.7 6.9e-26 90.4 1.7 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Wbp11 PF09429.10 OAG24938.1 - 1.8e-20 73.1 17.0 1.8e-20 73.1 17.0 2.7 2 1 0 2 2 2 1 WW domain binding protein 11 TMEM215 PF15746.5 OAG24938.1 - 0.14 11.6 0.7 0.26 10.7 0.7 1.4 1 0 0 1 1 1 0 TMEM215 family AMP-binding PF00501.28 OAG24940.1 - 1.2e-72 244.9 0.0 1.6e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3632 PF12311.8 OAG24941.1 - 1.9e-37 129.4 0.1 2.5e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Haem_degrading PF03928.14 OAG24942.1 - 6.9e-30 103.6 0.6 8.5e-30 103.3 0.6 1.1 1 0 0 1 1 1 1 Haem-degrading TruB_C PF09142.11 OAG24942.1 - 0.021 14.6 0.9 0.041 13.7 0.1 1.9 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Diacid_rec PF05651.13 OAG24942.1 - 0.21 11.3 2.7 9.4 5.9 1.0 2.2 2 0 0 2 2 2 0 Putative sugar diacid recognition FbpC_C_terminal PF17845.1 OAG24942.1 - 0.32 11.1 2.6 0.27 11.4 0.4 2.0 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain JmjC PF02373.22 OAG24943.1 - 0.034 14.6 0.0 0.14 12.5 0.0 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase LUC7 PF03194.15 OAG24943.1 - 0.066 12.9 0.2 0.094 12.4 0.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Ribosomal_L24e PF01246.20 OAG24944.1 - 1.7e-29 101.8 0.3 3.9e-29 100.7 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Ank_2 PF12796.7 OAG24945.1 - 2.3e-32 111.4 0.1 7.3e-14 52.1 0.2 4.0 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG24945.1 - 2.1e-24 85.6 0.3 6.9e-06 26.5 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG24945.1 - 3.8e-19 68.2 0.4 0.013 15.9 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OAG24945.1 - 2.1e-18 64.5 0.0 0.015 15.8 0.0 8.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OAG24945.1 - 5.9e-18 64.7 0.0 3.7e-06 27.1 0.0 5.3 2 1 2 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.12 OAG24945.1 - 1.6e-08 34.7 0.0 4.5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 OAG24945.1 - 1.8e-05 24.2 0.0 0.16 11.2 0.0 2.8 3 0 0 3 3 3 2 KAP family P-loop domain AAA_16 PF13191.6 OAG24945.1 - 0.00011 22.6 3.3 0.00082 19.8 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG24945.1 - 0.0014 18.9 0.0 0.0062 16.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain SR-25 PF10500.9 OAG24947.1 - 0.012 15.2 12.4 0.014 15.0 12.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Retrotran_gag_2 PF14223.6 OAG24947.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF5082 PF16888.5 OAG24947.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Ndc1_Nup PF09531.10 OAG24947.1 - 4 6.0 8.5 4.5 5.8 8.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_S8e PF01201.22 OAG24949.1 - 1.5e-54 183.8 2.0 1.8e-54 183.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Malate_synthase PF01274.22 OAG24950.1 - 3.1e-228 758.3 0.1 3.6e-228 758.1 0.1 1.0 1 0 0 1 1 1 1 Malate synthase SP24 PF16504.5 OAG24955.1 - 0.016 15.2 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus Terminase_5 PF06056.12 OAG24955.1 - 0.057 13.3 1.0 0.15 12.0 1.0 1.7 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GFO_IDH_MocA PF01408.22 OAG24956.1 - 8.5e-24 84.7 0.1 1.5e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG24956.1 - 3.1e-10 40.1 0.1 5.5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 OAG24956.1 - 5.5e-06 26.5 0.0 7.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Lysine_decarbox PF03641.14 OAG24957.1 - 8.2e-23 80.9 0.0 1.4e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAG24957.1 - 0.00051 19.7 0.1 0.0018 17.9 0.1 1.8 1 1 0 1 1 1 1 SLOG cluster4 family APH PF01636.23 OAG24958.1 - 1.9e-12 47.6 0.1 7.1e-12 45.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG24958.1 - 0.059 12.9 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase His_Phos_1 PF00300.22 OAG24960.1 - 3.1e-18 66.2 0.0 4.2e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMP-binding PF00501.28 OAG24961.1 - 2.1e-41 141.9 0.0 2.7e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG24961.1 - 0.0022 19.0 0.0 0.0046 17.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FOXP-CC PF16159.5 OAG24963.1 - 0.0022 18.6 2.1 0.0022 18.6 2.1 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain TPR_12 PF13424.6 OAG24964.1 - 1.9e-10 40.9 6.0 8.4e-05 22.8 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat Clr5 PF14420.6 OAG24964.1 - 0.00015 21.9 1.6 0.00087 19.5 1.5 2.4 2 0 0 2 2 2 1 Clr5 domain TPR_10 PF13374.6 OAG24964.1 - 0.0015 18.3 0.6 7.3 6.6 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat YfdX PF10938.8 OAG24964.1 - 0.0032 17.4 2.1 25 4.8 0.1 4.0 3 1 0 3 3 3 3 YfdX protein PE PF00934.20 OAG24965.1 - 0.15 12.4 0.9 0.37 11.1 0.9 1.6 1 0 0 1 1 1 0 PE family DUF2894 PF11445.8 OAG24965.1 - 2.4 8.6 5.5 4.9 7.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Seryl_tRNA_N PF02403.22 OAG24965.1 - 3 8.1 14.8 0.96 9.7 2.4 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tetraspanin PF00335.20 OAG24967.1 - 5.5e-05 23.0 2.1 0.00037 20.3 2.8 2.2 1 1 0 1 1 1 1 Tetraspanin family YndJ PF14158.6 OAG24967.1 - 1.6 8.0 7.0 0.2 10.9 0.7 2.4 3 0 0 3 3 3 0 YndJ-like protein FMN_red PF03358.15 OAG24969.1 - 6.5e-17 61.7 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAG24969.1 - 9.3e-08 32.0 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3632 PF12311.8 OAG24970.1 - 1.5e-19 71.1 0.2 2.2e-19 70.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FAD_binding_2 PF00890.24 OAG24971.1 - 1.2e-119 400.2 6.7 1.4e-119 399.9 6.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAG24971.1 - 2.5e-38 131.0 1.3 3.8e-38 130.4 1.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAG24971.1 - 1.6e-05 24.3 0.7 0.00029 20.2 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG24971.1 - 0.00045 19.5 0.6 0.079 12.2 0.2 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 OAG24971.1 - 0.0014 17.8 3.6 0.1 11.6 2.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAG24971.1 - 0.0023 17.2 0.6 0.0055 16.0 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG24971.1 - 0.015 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 OAG24971.1 - 0.023 14.3 2.1 0.11 12.1 2.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG24971.1 - 0.44 9.2 5.9 0.44 9.2 0.9 3.0 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG24971.1 - 0.98 8.6 3.9 1.2 8.3 1.6 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WW PF00397.26 OAG24972.1 - 1.3e-06 28.4 0.8 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 WW domain DUF2457 PF10446.9 OAG24972.1 - 0.19 10.8 14.9 0.26 10.4 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 OAG24972.1 - 1.1 7.7 4.7 1.3 7.4 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 OAG24972.1 - 5.6 6.3 7.0 8.2 5.8 7.0 1.2 1 0 0 1 1 1 0 SDA1 An_peroxidase PF03098.15 OAG24973.1 - 3e-37 128.4 0.0 1.9e-25 89.5 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAG24973.1 - 7.6e-09 34.8 0.0 6.7e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.16 OAG24974.1 - 2.4e-36 125.0 0.2 3.3e-36 124.5 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAG24974.1 - 0.00023 21.5 1.6 0.00073 19.9 0.6 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAG24974.1 - 0.0015 18.1 0.1 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ATE_C PF04377.15 OAG24975.1 - 1.3e-46 158.6 5.4 2.2e-46 157.8 5.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OAG24975.1 - 2.6e-23 82.2 0.0 1e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 OAG24975.1 - 0.19 11.9 1.6 0.43 10.7 1.6 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 OAG24976.1 - 1.5e-18 67.1 0.4 1.8e-18 66.9 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain VasL PF12486.8 OAG24976.1 - 1.6 8.6 6.3 0.12 12.2 1.5 1.6 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL Amidase PF01425.21 OAG24977.1 - 1.6e-28 99.9 0.0 2.7e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 OAG24978.1 - 2.4e-07 30.5 0.2 1.3e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG24978.1 - 0.00093 19.0 0.1 0.00093 19.0 0.1 2.5 3 0 0 3 3 3 1 F-box domain LysR_substrate PF03466.20 OAG24982.1 - 0.035 13.5 0.4 0.059 12.7 0.1 1.6 2 0 0 2 2 2 0 LysR substrate binding domain MASE2 PF05230.11 OAG24982.1 - 0.063 13.3 0.3 0.26 11.4 0.2 1.9 1 1 1 2 2 2 0 MASE2 domain DUF5453 PF17534.2 OAG24982.1 - 0.13 12.2 0.2 0.18 11.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Caleosin PF05042.13 OAG24983.1 - 5.6e-80 267.2 0.2 7e-80 266.9 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein DUF2371 PF10177.9 OAG24984.1 - 0.011 15.9 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) HET PF06985.11 OAG24985.1 - 6e-06 26.7 5.1 0.0069 16.7 0.3 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) SGL PF08450.12 OAG24987.1 - 0.0094 15.6 0.0 0.064 12.8 0.0 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region adh_short PF00106.25 OAG24988.1 - 9.2e-27 93.8 0.0 5.4e-26 91.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG24988.1 - 3.8e-18 65.9 0.0 1e-17 64.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG24988.1 - 2.1e-05 24.5 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG24988.1 - 0.0034 16.9 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG24988.1 - 0.046 13.5 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.18 OAG24989.1 - 7.5e-08 32.4 8.0 7.5e-08 32.4 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG24989.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MoeA_C PF03454.15 OAG24991.1 - 0.066 13.4 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) GATA PF00320.27 OAG24991.1 - 0.68 9.6 4.4 9.2 6.0 0.7 2.7 3 0 0 3 3 3 0 GATA zinc finger Trp_syntA PF00290.20 OAG24992.1 - 8.4e-93 310.0 0.0 1.6e-92 309.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OAG24992.1 - 8.5e-46 156.7 2.1 8.5e-46 156.7 2.1 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme SPX PF03105.19 OAG24992.1 - 9.6e-41 141.0 10.8 3.4e-27 96.4 6.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAG24992.1 - 1.7e-30 106.5 44.4 2.6e-30 105.9 44.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OAG24992.1 - 2.1e-26 92.9 67.2 1.6e-24 86.7 41.0 2.4 2 1 1 3 3 3 2 Citrate transporter Pkinase PF00069.25 OAG24993.1 - 6.1e-29 101.2 0.0 7.5e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG24993.1 - 4.7e-15 55.6 0.0 6.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4428 PF14471.6 OAG24994.1 - 0.034 14.1 0.4 22 5.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AdoHcyase PF05221.17 OAG24995.1 - 0.05 12.7 0.1 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase Peptidase_S10 PF00450.22 OAG24996.1 - 4.4e-77 260.3 0.1 5.8e-77 259.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase VIR_N PF15912.5 OAG24997.1 - 0.21 11.1 5.4 0.28 10.7 5.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal GET2 PF08690.10 OAG24997.1 - 1 9.0 4.2 1.3 8.6 4.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Macoilin PF09726.9 OAG24997.1 - 9.9 4.6 7.5 11 4.4 7.5 1.0 1 0 0 1 1 1 0 Macoilin family RSN1_7TM PF02714.15 OAG24998.1 - 2.8e-86 289.2 20.2 5.6e-86 288.3 20.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG24998.1 - 3.6e-45 153.5 4.3 1.8e-44 151.2 1.1 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG24998.1 - 9.4e-30 104.1 1.0 1.6e-29 103.4 1.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG24998.1 - 6.2e-19 68.0 0.0 2.1e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter TMEM154 PF15102.6 OAG24998.1 - 0.041 13.8 1.9 16 5.4 0.0 3.6 3 0 0 3 3 3 0 TMEM154 protein family Fib_alpha PF08702.10 OAG24998.1 - 0.11 12.7 1.1 0.2 11.8 1.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 OAG24999.1 - 1.5e-21 76.7 32.1 7.9e-14 51.3 13.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 OAG24999.1 - 0.058 13.1 0.1 0.058 13.1 0.1 3.4 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus HET PF06985.11 OAG25000.1 - 1.2e-24 87.3 0.0 2.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRP-alpha_N PF04086.13 OAG25001.1 - 1.3e-79 268.2 0.3 1.7e-79 267.8 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 OAG25001.1 - 4.4e-48 163.5 0.1 8.4e-48 162.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OAG25001.1 - 1e-09 38.5 0.1 3.8e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAG25001.1 - 2.5e-06 26.7 0.0 4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OAG25001.1 - 0.0014 18.4 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG25001.1 - 0.0029 18.0 0.1 0.0078 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OAG25001.1 - 0.028 14.9 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 OAG25001.1 - 0.051 14.0 1.6 0.095 13.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAG25001.1 - 0.12 12.4 0.1 0.39 10.8 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG25001.1 - 0.16 12.2 0.5 1.8 8.9 0.0 2.7 2 1 1 3 3 3 0 AAA domain YIF1 PF03878.15 OAG25002.1 - 3.9e-95 317.9 2.6 4.5e-95 317.7 2.6 1.0 1 0 0 1 1 1 1 YIF1 LRR_6 PF13516.6 OAG25003.1 - 0.00026 20.8 1.0 30 5.0 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 OAG25003.1 - 0.0047 17.3 5.2 39 5.4 0.0 6.0 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 OAG25003.1 - 0.0055 17.1 3.2 14 6.3 0.0 5.0 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) GATA PF00320.27 OAG25003.1 - 0.098 12.3 0.5 0.25 11.0 0.5 1.7 1 0 0 1 1 1 0 GATA zinc finger CDC45 PF02724.14 OAG25003.1 - 1.3 7.3 7.5 1.7 6.9 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OAG25003.1 - 2.7 7.7 7.9 4.8 6.9 7.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Stc1 PF12898.7 OAG25004.1 - 1.3e-21 76.9 14.5 2.5e-21 76.0 14.5 1.5 1 0 0 1 1 1 1 Stc1 domain Cwf_Cwc_15 PF04889.12 OAG25004.1 - 0.82 9.4 6.6 0.066 12.9 1.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 OAG25004.1 - 2.9 8.3 12.0 7.2 7.1 12.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HypA PF01155.19 OAG25004.1 - 3.4 7.7 8.5 4.5 7.3 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHY PF05495.12 OAG25004.1 - 7.5 7.1 11.8 2.1e+02 2.5 12.4 2.5 1 1 1 2 2 2 0 CHY zinc finger PolC_DP2 PF03833.13 OAG25004.1 - 8.3 4.1 6.6 11 3.7 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cpn60_TCP1 PF00118.24 OAG25005.1 - 1.4e-170 568.2 4.3 1.6e-170 568.0 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NusA_N PF08529.11 OAG25005.1 - 0.18 12.2 3.9 0.81 10.0 3.9 2.3 1 1 0 1 1 1 0 NusA N-terminal domain PASTA PF03793.19 OAG25006.1 - 0.045 13.6 0.2 1.1 9.2 0.1 2.5 3 0 0 3 3 3 0 PASTA domain TMEM190 PF15431.6 OAG25007.1 - 0.059 13.5 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Transmembrane protein 190 NAD_binding_10 PF13460.6 OAG25008.1 - 2e-24 86.5 0.6 2e-24 86.5 0.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG25008.1 - 3.5e-23 82.4 0.1 5.4e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG25008.1 - 0.018 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG25008.1 - 0.024 13.7 0.1 0.059 12.4 0.1 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG25008.1 - 0.06 12.8 0.2 0.24 10.8 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family HET PF06985.11 OAG25009.1 - 3.6e-32 111.7 0.6 6.5e-32 110.9 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG25010.1 - 2.7e-28 99.2 0.0 5.6e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EAP30 PF04157.16 OAG25011.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 EAP30/Vps36 family AA_permease_2 PF13520.6 OAG25012.1 - 2.2e-45 155.3 33.4 2.9e-42 145.0 25.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAG25012.1 - 3.5e-20 72.1 18.9 5.6e-20 71.4 18.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.6 OAG25012.1 - 3.4 7.9 6.0 2.7 8.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) CorA PF01544.18 OAG25013.1 - 4.3e-11 42.7 1.9 1.3e-10 41.1 1.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 OAG25017.1 - 3e-18 66.1 0.1 4.2e-17 62.4 0.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25017.1 - 5.2e-17 62.0 0.0 1e-11 44.7 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase DUF2075 PF09848.9 OAG25018.1 - 2.1e-60 204.9 0.0 2.7e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAG25018.1 - 2.5e-05 24.4 0.0 0.04 13.9 0.0 2.4 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG25018.1 - 0.00089 19.5 0.1 0.032 14.5 0.0 2.9 1 1 1 2 2 2 1 AAA domain GIY-YIG PF01541.24 OAG25018.1 - 0.0016 18.6 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain Mg_chelatase PF01078.21 OAG25018.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 OAG25018.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG25018.1 - 0.04 14.3 1.9 0.34 11.3 0.9 2.9 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 OAG25018.1 - 0.044 14.2 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG25018.1 - 0.05 14.2 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG25018.1 - 0.053 13.9 0.1 0.31 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG25018.1 - 0.072 13.0 0.5 0.35 10.8 0.5 2.1 1 1 0 1 1 1 0 NACHT domain DEAD PF00270.29 OAG25018.1 - 0.072 12.9 0.1 2.1 8.1 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 OAG25018.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GMC_oxred_N PF00732.19 OAG25019.1 - 6.5e-30 104.5 0.0 3.3e-28 98.9 0.0 3.2 3 1 0 3 3 3 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG25019.1 - 6.3e-26 91.6 0.0 1.3e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAG25019.1 - 0.00031 20.1 0.4 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG25019.1 - 0.0012 18.0 0.1 0.027 13.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25019.1 - 0.0026 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG25019.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG25019.1 - 0.009 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HHH_5 PF14520.6 OAG25019.1 - 0.15 12.7 0.1 0.79 10.4 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain PLDc PF00614.22 OAG25020.1 - 4.9e-17 61.3 0.7 2.5e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAG25020.1 - 2.9e-13 49.8 0.0 6.8e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAG25020.1 - 1.2e-09 38.1 0.0 6.2e-09 35.8 0.0 2.3 1 0 0 1 1 1 1 PX domain NAM-associated PF14303.6 OAG25021.1 - 0.053 14.2 0.2 0.076 13.7 0.2 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF5472 PF17566.2 OAG25021.1 - 0.16 11.9 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Hydrolase_4 PF12146.8 OAG25022.1 - 0.00017 20.9 0.1 0.0013 18.0 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CorA PF01544.18 OAG25023.1 - 5.6e-09 35.7 0.2 1.6e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF1989 PF09347.10 OAG25024.1 - 4.7e-14 52.4 0.2 2.2e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) Replicase PF03090.17 OAG25024.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Replicase family adh_short PF00106.25 OAG25029.1 - 4.2e-14 52.5 0.0 5.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25029.1 - 3.7e-08 33.2 0.0 5.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25029.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 OAG25029.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 OAG25029.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EphA2_TM PF14575.6 OAG25032.1 - 0.03 15.2 0.0 0.046 14.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PseudoU_synth_1 PF01416.20 OAG25034.1 - 2.2e-33 114.9 0.0 1e-31 109.6 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ubiquitin PF00240.23 OAG25035.1 - 0.0024 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Presenilin PF01080.17 OAG25035.1 - 0.83 8.4 4.0 0.91 8.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OAG25035.1 - 3.7 6.3 8.9 3.7 6.3 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIG-H PF10181.9 OAG25036.1 - 0.0031 17.4 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DIM1 PF02966.16 OAG25037.1 - 8e-69 229.5 0.1 9.1e-69 229.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 RicinB_lectin_2 PF14200.6 OAG25038.1 - 2.5e-14 53.8 4.4 4.1e-09 37.1 0.2 2.2 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Filamin PF00630.19 OAG25038.1 - 0.067 14.0 0.0 0.13 13.1 0.0 1.6 1 1 0 1 1 1 0 Filamin/ABP280 repeat MFS_1 PF07690.16 OAG25039.1 - 5e-32 111.2 32.8 5e-32 111.2 32.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0182 PF03699.13 OAG25039.1 - 0.011 14.0 0.2 0.017 13.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Ras PF00071.22 OAG25040.1 - 3.6e-18 65.7 0.0 1.4e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG25040.1 - 2.8e-06 27.5 0.0 1e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAG25040.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 OAG25040.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG25040.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase FANCF PF11107.8 OAG25040.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) AAA_25 PF13481.6 OAG25040.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG25040.1 - 0.19 12.3 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Peptidase_M14 PF00246.24 OAG25041.1 - 1e-41 143.7 1.2 1.3e-41 143.3 1.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase PRIMA1 PF16101.5 OAG25043.1 - 0.07 13.2 7.6 0.18 11.8 7.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3905 PF13045.6 OAG25044.1 - 0.059 13.4 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) Iso_dh PF00180.20 OAG25045.1 - 2.8e-76 256.9 0.0 3.3e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F-box-like PF12937.7 OAG25048.1 - 1.9e-06 27.6 0.2 6.2e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG25048.1 - 0.00093 19.0 0.2 0.0034 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain Transglut_core2 PF13369.6 OAG25048.1 - 0.048 13.2 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily EPSP_synthase PF00275.20 OAG25049.1 - 1.7e-126 422.3 0.0 2.2e-126 421.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAG25049.1 - 9.6e-102 339.6 0.0 1.5e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAG25049.1 - 2.1e-56 191.7 0.0 8.8e-56 189.7 0.0 2.0 3 0 0 3 3 3 1 Type I 3-dehydroquinase SKI PF01202.22 OAG25049.1 - 2.1e-36 125.5 0.0 2e-35 122.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 OAG25049.1 - 6.5e-20 71.2 0.0 1.6e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAG25049.1 - 2.2e-09 36.9 0.1 6e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 OAG25049.1 - 9.1e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 OAG25049.1 - 0.037 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_C15 PF01470.17 OAG25050.1 - 6.4e-15 55.9 0.0 8.4e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 Pyroglutamyl peptidase MFS_1 PF07690.16 OAG25051.1 - 8.6e-33 113.7 30.5 8.6e-33 113.7 30.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pribosyl_synth PF14572.6 OAG25055.1 - 6.5e-40 137.1 1.9 7.5e-35 120.6 0.7 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OAG25055.1 - 2.3e-35 121.1 0.0 6.7e-35 119.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OAG25055.1 - 7e-16 58.2 0.2 2.1e-15 56.6 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG25055.1 - 0.0015 18.1 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HoxA13_N PF12284.8 OAG25057.1 - 0.21 12.2 0.1 0.21 12.2 0.1 2.8 2 1 1 3 3 3 0 Hox protein A13 N terminal DUF2619 PF10942.8 OAG25057.1 - 0.34 11.0 0.9 0.5 10.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) GHMP_kinases_N PF00288.26 OAG25057.1 - 0.37 11.1 0.2 0.37 11.1 0.2 2.2 3 0 0 3 3 3 0 GHMP kinases N terminal domain QWRF PF04484.12 OAG25057.1 - 0.52 10.0 5.5 0.64 9.7 5.5 1.1 1 0 0 1 1 1 0 QWRF family Peptidase_M28 PF04389.17 OAG25058.1 - 6.2e-36 124.0 0.1 9.4e-36 123.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG25058.1 - 2.3e-12 46.8 0.4 5.5e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 OAG25058.1 - 0.00011 21.3 0.0 0.001 18.1 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 OAG25058.1 - 0.00021 21.1 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 OAG25058.1 - 0.089 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Nicastrin ICL PF00463.21 OAG25061.1 - 1.9e-296 983.6 3.0 2.1e-296 983.5 3.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG25061.1 - 6e-12 45.5 1.0 1e-10 41.5 0.2 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase DUF1365 PF07103.11 OAG25062.1 - 1.9e-58 197.9 0.0 2.7e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Tyr_Deacylase PF02580.16 OAG25064.1 - 3.4e-53 180.1 0.1 3.8e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2914 PF11141.8 OAG25064.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Not3 PF04065.15 OAG25065.1 - 1.7e-88 296.0 29.7 1.7e-88 296.0 29.7 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAG25065.1 - 1.9e-43 147.6 11.6 4.8e-43 146.4 11.6 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAG25065.1 - 0.0042 16.9 2.4 0.01 15.7 2.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CorA PF01544.18 OAG25065.1 - 0.025 13.9 6.1 0.015 14.7 3.6 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Chal_sti_synt_C PF02797.15 OAG25065.1 - 0.073 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF948 PF06103.11 OAG25065.1 - 0.39 11.0 4.3 0.49 10.7 1.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 OAG25065.1 - 0.44 10.5 5.5 0.79 9.7 0.2 2.7 1 1 1 2 2 2 0 Serine rich protein interaction domain Spc29 PF17082.5 OAG25065.1 - 0.83 9.5 12.6 0.025 14.4 2.4 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 Fib_alpha PF08702.10 OAG25065.1 - 3.8 7.7 18.9 1.1 9.5 7.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 OAG25065.1 - 5.5 6.2 18.6 5.8 6.1 8.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.6 OAG25065.1 - 8.2 6.9 17.4 0.12 12.8 2.1 2.9 3 0 0 3 3 3 0 Syntaxin-like protein zf-C2H2 PF00096.26 OAG25066.1 - 4.2e-05 23.8 5.0 0.082 13.4 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25066.1 - 0.21 12.5 2.3 7.3 7.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger IFRD PF05004.13 OAG25067.1 - 1.2e-81 274.2 11.1 1.9e-81 273.5 11.1 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Ku_PK_bind PF08785.11 OAG25067.1 - 0.012 15.7 0.1 0.036 14.2 0.1 1.8 1 0 0 1 1 1 0 Ku C terminal domain like MetOD2 PF18548.1 OAG25067.1 - 0.02 15.0 1.9 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 Metanogen output domain 2 Poty_PP PF08440.10 OAG25067.1 - 0.045 12.8 0.2 0.083 12.0 0.2 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein Phage_GP20 PF06810.11 OAG25067.1 - 0.27 11.1 4.1 0.27 11.0 1.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Pro_isomerase PF00160.21 OAG25068.1 - 2.7e-47 161.0 0.2 4.5e-47 160.3 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAG25068.1 - 0.00048 20.0 11.2 0.02 14.9 3.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG25068.1 - 0.012 15.4 13.7 0.15 11.9 2.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG25068.1 - 0.11 12.8 2.5 2 8.8 2.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG25068.1 - 0.89 9.3 4.5 5.4 6.8 0.0 3.6 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 OAG25068.1 - 8.5 6.9 12.6 0.52 10.7 0.9 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RasGAP PF00616.19 OAG25069.1 - 1.3e-29 103.4 18.4 2.3e-29 102.6 0.0 5.2 5 1 0 5 5 5 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 OAG25069.1 - 3.1e-06 27.4 0.0 4.4e-05 23.7 0.0 2.5 1 1 0 1 1 1 1 C2 domain PH PF00169.29 OAG25069.1 - 1.3e-05 25.6 0.0 0.019 15.5 0.0 3.4 3 0 0 3 3 3 2 PH domain TctB PF07331.11 OAG25071.1 - 1.1 9.6 15.3 0.019 15.3 6.4 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family YlaH PF14036.6 OAG25071.1 - 3.7 7.9 9.3 0.16 12.3 2.9 2.0 2 0 0 2 2 2 0 YlaH-like protein An_peroxidase PF03098.15 OAG25072.1 - 4.4e-120 401.8 0.0 5.5e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase ABC_membrane PF00664.23 OAG25073.1 - 6.7e-102 340.8 43.1 1.2e-53 182.6 20.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG25073.1 - 5.7e-68 227.7 0.0 1.1e-32 113.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG25073.1 - 4.8e-14 52.3 9.3 4.5e-06 26.2 1.8 5.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG25073.1 - 6.2e-09 36.5 2.9 0.0027 18.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG25073.1 - 4.2e-08 33.5 1.7 0.0051 17.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG25073.1 - 5.3e-07 29.3 3.6 0.013 15.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG25073.1 - 3.3e-06 27.2 0.5 0.035 13.9 0.0 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OAG25073.1 - 6.8e-06 26.7 0.0 0.048 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAG25073.1 - 1.5e-05 24.9 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 OAG25073.1 - 3e-05 23.3 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 OAG25073.1 - 4.9e-05 23.3 0.0 0.69 9.8 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase ABC_ATPase PF09818.9 OAG25073.1 - 0.0001 21.3 5.6 0.027 13.3 0.1 3.4 5 0 0 5 5 5 2 Predicted ATPase of the ABC class Ploopntkinase3 PF18751.1 OAG25073.1 - 0.00017 21.6 0.1 0.85 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 DUF87 PF01935.17 OAG25073.1 - 0.00019 21.6 0.1 1 9.4 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 OAG25073.1 - 0.00021 21.1 5.2 0.063 13.0 0.3 3.9 4 1 0 4 4 3 2 AAA domain Zeta_toxin PF06414.12 OAG25073.1 - 0.00024 20.4 0.4 0.14 11.4 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.14 OAG25073.1 - 0.00031 20.7 0.3 1.5 8.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG25073.1 - 0.00043 20.5 0.2 1.1 9.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 OAG25073.1 - 0.00053 20.3 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 OAG25073.1 - 0.00083 19.1 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OAG25073.1 - 0.0019 17.8 0.1 3.1 7.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain APS_kinase PF01583.20 OAG25073.1 - 0.0034 17.3 0.0 2.2 8.2 0.0 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 OAG25073.1 - 0.0037 17.8 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAG25073.1 - 0.0055 16.5 0.2 4.4 7.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAG25073.1 - 0.0087 16.3 5.2 1.7 9.0 0.5 4.2 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 OAG25073.1 - 0.021 14.2 0.3 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 OAG25073.1 - 0.021 15.2 0.1 7.7 7.0 0.0 3.2 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 OAG25073.1 - 0.025 14.7 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 OAG25073.1 - 0.03 13.5 0.2 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 OAG25073.1 - 0.038 13.9 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain CPT PF07931.12 OAG25073.1 - 0.05 13.4 0.1 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 OAG25073.1 - 0.063 12.7 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAG25073.1 - 0.078 12.5 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TruB_C PF09142.11 OAG25073.1 - 0.08 12.7 0.2 2 8.3 0.0 2.6 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal NACHT PF05729.12 OAG25073.1 - 0.13 12.1 0.7 16 5.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 OAG25073.1 - 0.15 12.5 0.4 10 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 OAG25073.1 - 0.16 11.7 0.3 20 4.9 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Tex_YqgF PF16921.5 OAG25073.1 - 0.19 12.2 1.0 3.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Tex protein YqgF-like domain Dynamin_N PF00350.23 OAG25073.1 - 0.4 10.7 1.7 32 4.5 0.1 2.9 2 1 0 2 2 2 0 Dynamin family DUF2852 PF11014.8 OAG25073.1 - 0.75 10.0 2.2 0.9 9.7 0.1 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF2852) DUF5516 PF17637.2 OAG25074.1 - 0.014 15.2 1.3 0.027 14.2 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5516) DUF1345 PF07077.11 OAG25074.1 - 0.25 11.0 1.1 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) FixS PF03597.15 OAG25074.1 - 0.65 9.8 0.0 0.65 9.8 0.0 3.0 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type Pkinase PF00069.25 OAG25075.1 - 6.2e-07 29.1 0.0 9.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAG25075.1 - 8.7e-06 24.8 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Lipocalin_2 PF08212.12 OAG25076.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OAG25076.1 - 0.054 13.7 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Big_1 PF02369.16 OAG25078.1 - 0.024 14.7 1.0 0.061 13.3 1.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Hemerythrin PF01814.23 OAG25079.1 - 0.044 14.4 0.2 0.076 13.6 0.2 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain F-box-like_2 PF13013.6 OAG25080.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain Exo_endo_phos PF03372.23 OAG25081.1 - 9.7e-09 35.1 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Actin PF00022.19 OAG25082.1 - 2.5e-127 424.9 0.0 1.2e-126 422.7 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG25082.1 - 0.00056 18.8 0.0 0.0054 15.6 0.0 2.3 1 1 0 1 1 1 1 MreB/Mbl protein DUF4692 PF15763.5 OAG25082.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF3602 PF12223.8 OAG25083.1 - 1.1e-20 74.0 11.0 1.2e-18 67.5 0.5 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) SH2_2 PF14633.6 OAG25084.1 - 6.8e-79 264.3 0.0 6.8e-79 264.3 0.0 2.0 2 0 0 2 2 1 1 SH2 domain YqgF PF14639.6 OAG25084.1 - 1.9e-37 128.4 0.1 3.1e-36 124.4 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 OAG25084.1 - 6.8e-32 110.3 0.3 1.7e-31 109.0 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 OAG25084.1 - 1.2e-28 99.4 0.0 3.2e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 OAG25084.1 - 1.1e-13 51.6 26.6 1.1e-13 51.6 26.6 4.8 5 0 0 5 5 3 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 OAG25084.1 - 6.4e-05 23.8 1.1 6.4e-05 23.8 1.1 3.7 2 1 0 2 2 1 1 HHH domain SH2 PF00017.24 OAG25084.1 - 0.00017 21.6 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 OAG25084.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Tex protein YqgF-like domain HHH_3 PF12836.7 OAG25084.1 - 0.033 14.4 0.1 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif SOAR PF16533.5 OAG25084.1 - 0.04 13.9 0.0 0.19 11.7 0.0 2.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region ICA69 PF04629.14 OAG25084.1 - 0.042 14.2 9.1 0.11 12.7 9.1 1.7 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain POTRA_1 PF08478.10 OAG25084.1 - 0.058 13.7 0.0 0.43 10.9 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Orexin_rec2 PF03827.13 OAG25084.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Orexin receptor type 2 NBD94 PF16830.5 OAG25084.1 - 0.73 10.3 5.6 0.44 11.0 2.2 2.5 3 0 0 3 3 2 0 Nucleotide-Binding Domain 94 of RH Pkinase PF00069.25 OAG25085.1 - 1.4e-65 221.3 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25085.1 - 1.6e-38 132.5 0.0 2.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG25085.1 - 0.0015 17.6 0.1 0.0034 16.4 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG25085.1 - 0.0026 16.6 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG25085.1 - 0.018 15.0 0.0 0.05 13.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG25085.1 - 0.019 14.3 0.1 0.061 12.6 0.0 1.8 2 1 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OAG25085.1 - 0.091 12.4 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family F-box-like PF12937.7 OAG25086.1 - 0.018 14.9 2.6 0.019 14.9 0.4 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAG25086.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.7 3 0 0 3 3 3 0 F-box domain Solute_trans_a PF03619.16 OAG25087.1 - 2.1e-55 188.1 9.9 2.6e-55 187.8 9.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UcrQ PF02939.16 OAG25087.1 - 0.13 12.2 0.3 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 UcrQ family MerC PF03203.14 OAG25087.1 - 0.23 11.9 12.3 0.19 12.2 5.5 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein DUF1772 PF08592.11 OAG25087.1 - 6.5 7.1 7.4 6.7 7.0 2.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) BING4CT PF08149.11 OAG25088.1 - 3.7e-39 132.4 0.0 1.7e-34 117.4 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 OAG25088.1 - 0.00011 22.4 0.0 1.4 9.2 0.0 4.2 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG25088.1 - 0.00048 20.9 0.2 0.025 15.4 0.1 3.3 2 1 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.6 OAG25088.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain RIBIOP_C PF04950.12 OAG25089.1 - 3.4e-110 368.0 0.1 2.9e-109 365.0 0.0 2.4 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG25089.1 - 7.9e-19 67.5 0.0 2e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Lyase_1 PF00206.20 OAG25092.1 - 4.9e-92 308.7 0.0 8.2e-92 307.9 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAG25092.1 - 5.9e-23 81.4 0.1 2.2e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF2573 PF10835.8 OAG25092.1 - 0.16 12.3 0.2 0.78 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) MFS_1 PF07690.16 OAG25094.1 - 1.3e-25 90.1 38.7 5.3e-24 84.8 24.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily fn3_3 PF14686.6 OAG25096.1 - 1.1e-27 95.6 0.2 2.6e-27 94.4 0.2 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 OAG25096.1 - 6.5e-23 81.4 0.4 1.1e-22 80.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 OAG25096.1 - 0.028 14.7 0.0 0.091 13.1 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain PP2C_2 PF13672.6 OAG25096.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C PAPA-1 PF04795.12 OAG25097.1 - 2.9e-28 98.5 6.1 2.9e-28 98.5 6.1 3.3 2 1 1 3 3 3 1 PAPA-1-like conserved region NmrA PF05368.13 OAG25098.1 - 2.8e-31 108.9 0.1 3.3e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG25098.1 - 5.6e-17 62.2 0.1 2.6e-15 56.8 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG25098.1 - 1.9e-06 28.2 0.0 4.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG25098.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family BPL_LplA_LipB PF03099.19 OAG25098.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family DapB_N PF01113.20 OAG25098.1 - 0.13 12.4 0.6 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Mg296 PF09644.10 OAG25099.1 - 0.32 11.1 1.3 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Mg296 protein BTB PF00651.31 OAG25100.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Imm52 PF15579.6 OAG25100.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 52 DnaJ PF00226.31 OAG25101.1 - 2.7e-20 72.2 0.2 5.3e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain OTT_1508_deam PF14441.6 OAG25102.1 - 9.1e-18 64.0 0.3 2.6e-17 62.5 0.3 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.18 OAG25102.1 - 0.025 14.7 8.2 0.061 13.4 8.2 1.7 1 0 0 1 1 1 0 MYND finger CtaG_Cox11 PF04442.14 OAG25103.1 - 3.7e-60 202.3 0.2 8e-60 201.2 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-HIT PF04438.16 OAG25104.1 - 1.1e-11 44.4 10.1 1.4e-11 44.0 10.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 OAG25104.1 - 0.0036 17.4 8.2 0.0059 16.7 8.2 1.3 1 0 0 1 1 1 1 MYND finger PRIMA1 PF16101.5 OAG25104.1 - 0.058 13.4 3.6 0.086 12.9 3.6 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-B_box PF00643.24 OAG25104.1 - 0.091 12.9 6.2 0.14 12.3 6.2 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C6H2 PF15801.5 OAG25104.1 - 0.11 12.9 8.6 0.23 11.8 8.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 OAG25104.1 - 0.23 11.6 4.7 0.51 10.5 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Gln-synt_C PF00120.24 OAG25106.1 - 4.8e-85 285.6 0.0 5.8e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1201 PF06716.11 OAG25106.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) adh_short_C2 PF13561.6 OAG25107.1 - 9.4e-58 195.5 0.1 1.1e-57 195.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG25107.1 - 9e-42 142.7 0.1 1.1e-41 142.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG25107.1 - 3.1e-10 40.3 0.4 4.5e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG25107.1 - 6.4e-06 26.2 0.1 1.5e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG25107.1 - 0.0042 16.7 0.2 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 OAG25107.1 - 0.0089 16.7 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 OAG25107.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.12 OAG25107.1 - 0.023 15.4 0.0 0.064 14.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 OAG25107.1 - 0.025 13.8 0.3 0.32 10.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG25107.1 - 0.033 14.7 0.9 0.088 13.4 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RecC_C PF17946.1 OAG25107.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Aldedh PF00171.22 OAG25108.1 - 3.9e-123 411.4 0.0 4.9e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rpr2 PF04032.16 OAG25109.1 - 1.5e-22 79.6 0.0 2.4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 OAG25109.1 - 0.063 13.4 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain HNH_5 PF14279.6 OAG25109.1 - 0.26 11.2 2.5 10 6.1 2.8 2.3 1 1 1 2 2 2 0 HNH endonuclease DEAD PF00270.29 OAG25110.1 - 2.3e-37 128.4 0.0 3.7e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG25110.1 - 4.8e-25 88.1 0.1 2.2e-23 82.7 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG25110.1 - 1.6e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG25110.1 - 0.0024 17.3 0.0 0.0067 15.8 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 OAG25110.1 - 0.014 15.9 0.8 0.033 14.7 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) ApbA PF02558.16 OAG25111.1 - 4.5e-26 91.3 0.0 6.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG25111.1 - 7.5e-22 77.8 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Hexokinase_2 PF03727.16 OAG25112.1 - 1.9e-76 256.7 0.0 2.7e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG25112.1 - 3.6e-75 252.2 0.1 5.7e-75 251.6 0.1 1.3 1 0 0 1 1 1 1 Hexokinase DUF1967 PF09269.11 OAG25114.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) SH3-RhoG_link PF16609.5 OAG25114.1 - 0.16 11.6 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region CorA PF01544.18 OAG25115.1 - 1.8e-10 40.6 1.2 2.6e-10 40.1 1.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2274 PF10038.9 OAG25115.1 - 0.09 13.2 0.7 0.19 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) Integrase_DNA PF02920.15 OAG25115.1 - 0.18 11.5 1.0 3.7 7.3 0.0 2.9 3 0 0 3 3 3 0 DNA binding domain of tn916 integrase DNA_pol3_delta2 PF13177.6 OAG25117.1 - 1.7e-10 40.9 0.0 4.5e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAG25117.1 - 4e-06 27.3 0.3 9.8e-06 26.0 0.1 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG25117.1 - 5.4e-06 26.7 1.2 0.00039 20.7 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG25117.1 - 0.00032 21.1 2.2 0.0048 17.3 0.5 2.9 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 OAG25117.1 - 0.00053 20.4 0.5 0.0017 18.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 OAG25117.1 - 0.00074 19.3 1.1 0.0052 16.5 0.4 2.3 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAG25117.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 OAG25117.1 - 0.017 15.6 0.1 0.059 13.9 0.1 2.0 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 OAG25117.1 - 0.075 11.8 0.1 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer DNA_pol3_delta PF06144.13 OAG25117.1 - 0.081 12.7 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 OAG25117.1 - 0.16 12.0 0.4 0.48 10.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 OAG25119.1 - 2.4e-33 115.5 23.9 2.4e-33 115.5 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 OAG25119.1 - 0.0049 16.4 2.0 0.021 14.4 2.0 2.2 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 DUF3984 PF13136.6 OAG25119.1 - 2.2 7.6 5.8 7.2 5.9 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) Ribosomal_L37ae PF01780.19 OAG25120.1 - 5.6e-41 138.5 10.0 6.2e-41 138.4 10.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAG25120.1 - 0.00058 19.9 1.3 0.00082 19.5 1.3 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 OAG25120.1 - 0.017 15.2 0.5 0.023 14.8 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 OAG25120.1 - 0.021 15.2 0.2 4.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OAG25120.1 - 0.021 14.8 2.6 0.038 14.0 2.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ima1_N PF09779.9 OAG25120.1 - 0.031 15.1 0.1 0.042 14.7 0.1 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain A2L_zn_ribbon PF08792.10 OAG25120.1 - 0.081 12.7 0.1 0.081 12.7 0.1 1.7 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.14 OAG25120.1 - 0.082 13.3 3.6 1.9 8.9 0.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CarbpepA_inh PF02977.15 OAG25120.1 - 0.094 12.5 4.6 0.42 10.4 0.4 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-BED PF02892.15 OAG25120.1 - 0.11 12.5 5.7 1.3 9.1 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 OAG25120.1 - 0.26 11.6 2.4 6.7 7.1 2.5 2.0 1 1 1 2 2 2 0 C1 domain Methyltransf_23 PF13489.6 OAG25122.1 - 1.6e-13 50.8 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG25122.1 - 4.6e-07 30.4 0.0 3.6e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG25122.1 - 6.9e-07 29.2 0.0 2.9e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG25122.1 - 1.4e-05 25.7 0.0 5e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG25122.1 - 0.00027 21.6 0.0 0.0073 17.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DUF5606 PF18347.1 OAG25122.1 - 0.045 13.9 0.5 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5606) Ubie_methyltran PF01209.18 OAG25122.1 - 0.17 11.2 0.0 0.44 9.8 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 OAG25123.1 - 3.1e-37 127.9 0.0 4.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25123.1 - 1.9e-22 80.0 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25123.1 - 0.012 15.5 0.0 0.055 13.4 0.0 1.9 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 OAG25123.1 - 0.095 12.1 0.2 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF2663 PF10864.8 OAG25125.1 - 0.24 11.8 0.5 0.6 10.5 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) MmgE_PrpD PF03972.14 OAG25126.1 - 2.1e-145 484.7 0.0 2.6e-145 484.3 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Adhesin_E PF16747.5 OAG25128.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Surface-adhesin protein E WH1 PF00568.23 OAG25129.1 - 7e-28 96.8 0.0 9.9e-28 96.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 OAG25129.1 - 1.3e-06 28.0 0.8 3e-06 26.9 0.8 1.6 1 0 0 1 1 1 1 WH2 motif Glyco_transf_15 PF01793.16 OAG25132.1 - 6e-96 321.5 4.5 1e-95 320.7 4.5 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase BORCS6 PF10157.9 OAG25133.1 - 0.006 16.8 0.0 0.0074 16.5 0.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Ferric_reduct PF01794.19 OAG25134.1 - 1.1e-19 70.8 10.3 1.1e-19 70.8 10.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG25134.1 - 1.3e-19 70.8 0.0 1.1e-18 67.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG25134.1 - 1.7e-12 47.4 0.0 4.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG25134.1 - 0.00012 22.7 0.0 0.044 14.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAG25134.1 - 6.1 7.5 15.0 0.14 12.7 1.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) MFS_1 PF07690.16 OAG25135.1 - 3.5e-26 92.0 21.2 3.5e-26 92.0 21.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG25135.1 - 1.9e-06 26.6 3.6 2.9e-06 26.0 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.26 OAG25136.1 - 3.1e-11 43.1 27.7 0.015 15.7 0.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25136.1 - 3.4e-07 30.5 30.3 0.013 16.2 0.6 6.1 6 0 0 6 6 5 4 C2H2-type zinc finger zf-met PF12874.7 OAG25136.1 - 2.5e-06 27.7 25.8 0.0024 18.2 0.7 5.0 5 0 0 5 5 4 3 Zinc-finger of C2H2 type DNA_pol_A_exo1 PF01612.20 OAG25136.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2_6 PF13912.6 OAG25136.1 - 0.047 13.7 0.4 0.047 13.7 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OAG25136.1 - 0.048 14.3 9.0 0.044 14.5 4.3 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 OAG25136.1 - 0.082 13.0 5.0 33 4.7 0.1 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 OAG25136.1 - 0.15 11.9 16.2 4.1 7.2 0.2 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAG25136.1 - 0.49 10.8 20.6 3.5 8.0 0.7 4.7 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OAG25136.1 - 1.5 9.3 7.9 21 5.7 0.1 4.2 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 OAG25136.1 - 1.8 9.4 12.3 7.2 7.4 0.2 3.4 2 1 0 2 2 2 0 zinc-ribbon family zf-piccolo PF05715.13 OAG25136.1 - 3.3 7.9 9.0 0.51 10.5 0.2 3.4 4 0 0 4 4 3 0 Piccolo Zn-finger C1_1 PF00130.22 OAG25136.1 - 5.8 6.9 13.7 2.2 8.3 1.0 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 OAG25136.1 - 6.5 7.4 9.7 16 6.2 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger double domain His_Phos_1 PF00300.22 OAG25137.1 - 8.3e-36 123.5 0.2 6.3e-19 68.4 0.1 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CBM_1 PF00734.18 OAG25138.1 - 9.2e-09 35.1 12.6 2e-08 34.0 12.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Acetyltransf_1 PF00583.25 OAG25138.1 - 2.1e-08 34.4 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG25138.1 - 0.0024 18.3 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG25138.1 - 0.003 17.5 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OAG25138.1 - 0.018 15.0 0.1 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 OAG25138.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF1690 PF07956.11 OAG25139.1 - 2e-32 112.5 19.4 6.8e-32 110.8 19.4 1.7 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) APG6_N PF17675.1 OAG25139.1 - 0.13 12.8 21.0 0.49 10.9 18.6 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4240 PF14024.6 OAG25139.1 - 0.18 12.0 3.1 0.13 12.5 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4240) DUF4407 PF14362.6 OAG25139.1 - 0.27 10.5 10.4 0.34 10.2 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OAG25139.1 - 0.28 10.2 12.2 0.33 10.0 12.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PepSY_TM_like_2 PF16357.5 OAG25139.1 - 0.65 10.0 3.2 0.94 9.4 3.2 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like PilO PF04350.13 OAG25139.1 - 2.1 8.5 10.9 0.29 11.3 5.6 2.1 1 1 1 2 2 2 0 Pilus assembly protein, PilO DUF327 PF03885.13 OAG25139.1 - 4.7 7.2 15.4 38 4.2 15.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DNA_methylase PF00145.17 OAG25140.1 - 3.5e-34 118.7 0.0 2.8e-22 79.5 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Rick_17kDa_Anti PF05433.15 OAG25143.1 - 0.0009 19.1 15.3 0.0014 18.5 15.3 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAG25143.1 - 0.73 9.9 9.9 1.2 9.2 9.9 1.3 1 0 0 1 1 1 0 Glycine zipper PIP5K PF01504.18 OAG25144.1 - 1.7e-44 152.1 0.0 1.6e-42 145.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SnoaL PF07366.12 OAG25145.1 - 0.00081 19.2 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG25145.1 - 0.028 15.1 0.0 0.096 13.3 0.0 2.0 2 1 0 2 2 2 0 SnoaL-like domain Cyclin PF08613.11 OAG25147.1 - 8.9e-06 26.2 2.1 1.4e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 OAG25147.1 - 0.0047 16.7 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pro_dh PF01619.18 OAG25148.1 - 2.6e-51 174.9 0.0 3.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase P5CR_dimer PF14748.6 OAG25148.1 - 8e-30 103.1 0.7 1.8e-29 102.0 0.3 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG25148.1 - 7.4e-09 36.1 0.0 2e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 OAG25148.1 - 0.12 11.8 0.1 0.35 10.3 0.1 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DAO PF01266.24 OAG25150.1 - 1.8e-33 116.6 0.0 2e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG25150.1 - 2.5e-06 27.6 0.0 7.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG25150.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG25150.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 OAG25150.1 - 0.0066 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25150.1 - 0.0096 15.2 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG25150.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 OAG25150.1 - 0.016 14.5 0.0 3.7 6.7 0.0 2.2 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG25150.1 - 0.022 15.3 0.4 0.14 12.8 0.0 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG25150.1 - 0.03 14.3 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG25150.1 - 0.047 12.4 0.0 0.54 8.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAG25150.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 OAG25151.1 - 9.8e-13 47.7 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAG25152.1 - 3.5e-92 309.3 0.0 4.4e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_3 PF13606.6 OAG25153.1 - 4.9e-12 44.9 0.3 0.43 11.3 0.0 6.7 7 1 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OAG25153.1 - 2e-10 40.6 0.3 0.61 10.6 0.0 6.0 5 1 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 OAG25153.1 - 5.7e-10 39.7 0.0 4.3e-05 24.0 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG25153.1 - 2.7e-09 37.1 0.0 0.008 16.5 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG25153.1 - 2e-06 28.2 0.0 2.9 8.6 0.0 4.7 4 1 0 5 5 5 2 Ankyrin repeats (many copies) Rgp1 PF08737.10 OAG25154.1 - 1.3e-153 512.1 0.0 4.9e-153 510.2 0.0 2.0 3 0 0 3 3 3 1 Rgp1 Arrestin_N PF00339.29 OAG25154.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ISG65-75 PF11727.8 OAG25155.1 - 0.21 10.8 4.3 0.26 10.5 4.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Asp PF00026.23 OAG25156.1 - 2.2e-14 53.6 0.3 3.1e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG25156.1 - 0.009 16.3 0.1 0.025 14.8 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4690 PF15756.5 OAG25156.1 - 0.014 16.0 0.1 0.051 14.2 0.1 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 OAG25156.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Podoplanin C_GCAxxG_C_C PF09719.10 OAG25156.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) CD34_antigen PF06365.12 OAG25156.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family OMP_b-brl PF13505.6 OAG25156.1 - 1.1 9.3 6.2 2 8.5 4.3 2.5 2 1 0 2 2 2 0 Outer membrane protein beta-barrel domain DUF4178 PF13785.6 OAG25157.1 - 0.0011 19.1 0.0 1.3 9.1 0.0 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4178) DUF1378 PF07125.11 OAG25158.1 - 0.056 13.6 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) OSCP PF00213.18 OAG25159.1 - 1.3e-45 155.6 1.7 1.8e-45 155.2 1.7 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PA28_alpha PF02251.18 OAG25159.1 - 0.012 15.7 0.6 0.3 11.2 0.1 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DUF4444 PF14563.6 OAG25159.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Trimer_CC PF08954.11 OAG25159.1 - 0.16 11.6 0.7 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Trimerisation motif DUF2597 PF10772.9 OAG25160.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) DUF4754 PF15946.5 OAG25161.1 - 0.053 13.8 0.0 1.6 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) CLN3 PF02487.17 OAG25162.1 - 4e-164 546.4 5.0 4.6e-164 546.2 5.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 OAG25162.1 - 1.4e-05 24.2 5.0 1.4e-05 24.2 5.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Rxt3 PF08642.10 OAG25164.1 - 2.1e-33 115.8 0.2 7e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAG25164.1 - 4.9e-05 23.4 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 LCCL domain 6PF2K PF01591.18 OAG25165.1 - 1.6e-82 276.2 0.1 2.3e-82 275.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG25165.1 - 3e-36 125.0 0.0 5.2e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG25165.1 - 4.7e-06 26.8 0.0 8.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG25165.1 - 0.0005 19.6 0.0 0.0011 18.5 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 SF3b10 PF07189.11 OAG25166.1 - 0.014 15.5 0.5 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) BCDHK_Adom3 PF10436.9 OAG25167.1 - 5.3e-73 244.2 0.0 7.7e-73 243.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG25167.1 - 7.7e-13 48.9 0.0 1.8e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG25167.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cytochrom_C PF00034.21 OAG25168.1 - 9.3e-11 42.7 0.0 1.2e-10 42.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAG25168.1 - 4e-08 33.5 1.1 2e-07 31.2 1.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAG25168.1 - 0.0094 15.7 1.7 0.046 13.4 1.7 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain adh_short PF00106.25 OAG25169.1 - 1.6e-26 93.0 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25169.1 - 4.4e-18 65.7 0.0 5.6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25169.1 - 8.7e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG25169.1 - 0.0011 18.5 0.0 0.003 17.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG25169.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Halo_GVPC PF05465.13 OAG25169.1 - 0.098 12.9 0.6 0.3 11.4 0.6 1.8 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3506 PF12014.8 OAG25169.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) DUF2236 PF09995.9 OAG25171.1 - 1.4e-33 117.0 0.1 2e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2593 PF10767.9 OAG25172.1 - 0.0086 16.2 1.1 0.018 15.1 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2593) DUF5392 PF17370.2 OAG25172.1 - 0.43 10.7 2.7 0.39 10.8 0.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5392) Neugrin PF06413.11 OAG25173.1 - 9.5e-14 51.9 0.3 1.5e-13 51.3 0.3 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 OAG25173.1 - 5.8e-08 33.1 1.9 9.6e-08 32.4 1.9 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 OAG25173.1 - 0.019 15.6 1.3 0.055 14.1 0.1 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_DeoR PF08220.12 OAG25173.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain ADH_N PF08240.12 OAG25174.1 - 5.1e-26 90.7 0.9 1.1e-25 89.6 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG25174.1 - 1.1e-24 86.8 0.8 1.9e-24 86.1 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG25174.1 - 5.8e-06 27.4 0.2 9.8e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG25174.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AIRC PF00731.20 OAG25174.1 - 0.037 13.6 2.2 0.71 9.4 0.5 2.5 2 0 0 2 2 2 0 AIR carboxylase Pkinase PF00069.25 OAG25175.1 - 8.3e-67 225.3 0.0 1.3e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25175.1 - 1e-46 159.3 0.0 1.8e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 OAG25175.1 - 1.2e-24 86.5 0.0 2.9e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 OAG25175.1 - 1.4e-16 60.7 0.4 2.9e-16 59.6 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAG25175.1 - 6.7e-16 58.1 0.3 1.7e-15 56.9 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 OAG25175.1 - 1.5e-06 27.8 0.2 0.0032 16.8 0.0 2.8 3 0 0 3 3 3 2 Kinase-like RA PF00788.23 OAG25175.1 - 9.9e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 OAG25175.1 - 0.0028 17.6 0.1 0.0066 16.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 OAG25175.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 IGR protein motif SAM_PNT PF02198.16 OAG25175.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Seadorna_VP7 PF07387.11 OAG25175.1 - 0.098 11.7 0.1 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAG25175.1 - 0.1 11.3 0.2 0.4 9.4 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase AflR PF08493.10 OAG25177.1 - 7.3 6.0 11.7 8.1 5.8 11.7 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein UBA PF00627.31 OAG25179.1 - 6.2e-05 22.8 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain F-box-like PF12937.7 OAG25179.1 - 0.015 15.2 0.0 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAG25179.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box domain SKG6 PF08693.10 OAG25180.1 - 0.00014 21.2 0.4 0.00031 20.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 OAG25180.1 - 0.0052 16.9 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) BatD PF13584.6 OAG25180.1 - 0.016 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance TMEM51 PF15345.6 OAG25180.1 - 0.03 14.2 0.2 0.049 13.5 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.14 OAG25180.1 - 0.046 13.8 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rax2 PF12768.7 OAG25180.1 - 0.069 12.6 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity STALD PF18185.1 OAG25180.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family SOG2 PF10428.9 OAG25180.1 - 0.71 9.0 5.3 1 8.5 5.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ifi-6-16 PF06140.13 OAG25181.1 - 8.3e-09 35.3 20.8 1.7e-08 34.2 20.8 1.6 1 0 0 1 1 1 1 Interferon-induced 6-16 family Apolipoprotein PF01442.18 OAG25181.1 - 0.0084 16.0 0.0 0.015 15.2 0.0 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain cwf18 PF08315.12 OAG25182.1 - 0.91 10.2 4.2 18 6.0 0.1 2.6 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor DUF3306 PF11748.8 OAG25182.1 - 3.3 8.6 6.4 1.1 10.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) zf-TFIIB PF13453.6 OAG25184.1 - 0.023 14.0 0.5 0.049 13.0 0.5 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger MPC PF03650.13 OAG25185.1 - 2e-47 159.9 0.1 2.6e-47 159.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 OAG25186.1 - 1.4e-15 56.9 0.0 1.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Fib_alpha PF08702.10 OAG25188.1 - 0.00058 20.1 14.6 0.0044 17.2 5.5 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 OAG25188.1 - 0.0021 17.8 15.4 0.0034 17.2 0.6 3.9 3 1 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Mod_r PF07200.13 OAG25188.1 - 0.011 15.9 22.3 0.068 13.3 10.3 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 OAG25188.1 - 0.037 14.4 20.0 0.3 11.5 10.4 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) MCC-bdg_PDZ PF10506.9 OAG25188.1 - 0.85 9.7 7.3 0.68 10.0 1.2 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Peptidase_S49_N PF08496.10 OAG25188.1 - 1 9.4 6.5 0.69 10.0 4.2 1.8 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Iron_permease PF04120.12 OAG25188.1 - 1.1 9.1 6.0 0.65 9.8 3.7 1.8 2 1 0 2 2 2 0 Low affinity iron permease Allexi_40kDa PF05549.11 OAG25188.1 - 1.4 8.3 6.5 1.7 8.1 5.3 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein CC2-LZ PF16516.5 OAG25188.1 - 1.6 9.1 19.8 2.5 8.5 5.1 4.0 2 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ATG16 PF08614.11 OAG25188.1 - 1.9 8.6 28.4 0.35 11.1 9.9 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 OAG25188.1 - 2.4 8.8 14.5 2.5 8.8 0.6 3.1 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Dam1 PF08653.10 OAG25188.1 - 3.4 7.5 5.6 35 4.3 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 OAG25188.1 - 3.8 8.0 8.5 28 5.2 0.4 4.2 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 OAG25188.1 - 7.3 5.8 17.5 1.1 8.5 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OAG25188.1 - 9.9 5.6 17.7 50 3.3 17.7 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fungal_trans_2 PF11951.8 OAG25189.1 - 5.8e-57 193.2 1.2 7.9e-57 192.8 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG25189.1 - 9.4e-06 25.7 12.0 1.6e-05 24.9 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ifi-6-16 PF06140.13 OAG25190.1 - 1.5e-08 34.5 32.8 3.5e-08 33.2 32.7 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 OAG25190.1 - 0.0049 17.5 0.4 0.0049 17.5 0.4 2.6 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF883) DUF2937 PF11157.8 OAG25190.1 - 0.19 11.5 5.0 0.22 11.2 0.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) DUF1548 PF07579.11 OAG25190.1 - 0.25 11.7 3.7 6.4 7.1 0.1 2.9 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1548) Zn_ribbon_17 PF17120.5 OAG25191.1 - 7.5e-17 60.7 12.6 1.3e-16 59.9 12.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 OAG25191.1 - 5.1e-06 27.1 11.7 0.0094 16.8 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 OAG25191.1 - 1.6 9.1 9.9 3.3 8.1 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.26 OAG25192.1 - 1.1e-45 154.8 0.0 1.2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG25192.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG25192.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 UEV domain PQQ_2 PF13360.6 OAG25194.1 - 0.00027 20.6 2.2 0.89 9.1 0.1 3.7 2 1 2 4 4 4 2 PQQ-like domain PQQ_3 PF13570.6 OAG25194.1 - 0.013 16.0 9.8 0.18 12.4 0.2 4.8 5 1 0 5 5 5 0 PQQ-like domain Sugar_tr PF00083.24 OAG25195.1 - 2.6e-82 277.1 16.2 3.1e-82 276.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG25195.1 - 9.2e-23 80.7 21.2 1.6e-17 63.5 0.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 OAG25197.1 - 2.1e-49 167.6 0.0 2.8e-26 92.6 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG25197.1 - 2.3e-16 60.5 1.4 4.9e-05 23.3 0.0 4.6 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG25197.1 - 9.9e-13 48.0 0.6 0.0015 18.0 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG25197.1 - 1.3e-07 32.4 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OAG25197.1 - 5.3e-07 29.7 0.0 0.0048 17.0 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.24 OAG25197.1 - 1.3e-06 28.2 0.1 2.8e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 OAG25197.1 - 1.9e-06 27.5 1.0 0.021 14.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG25197.1 - 3.6e-06 27.0 0.1 0.038 13.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 OAG25197.1 - 3.8e-05 24.0 0.0 0.021 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG25197.1 - 6.9e-05 23.1 0.0 0.6 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OAG25197.1 - 7.3e-05 22.7 0.1 0.05 13.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 OAG25197.1 - 0.00021 21.1 0.0 0.2 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 OAG25197.1 - 0.00061 19.9 0.7 0.18 11.9 0.1 3.2 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_18 PF13238.6 OAG25197.1 - 0.0017 18.9 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAG25197.1 - 0.0047 16.0 0.3 1 8.3 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OAG25197.1 - 0.0047 17.3 0.1 3.4 8.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OAG25197.1 - 0.0048 17.1 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 OAG25197.1 - 0.0055 15.4 0.0 1.2 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OAG25197.1 - 0.0069 16.5 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 OAG25197.1 - 0.0069 16.6 0.0 3.3 8.0 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 OAG25197.1 - 0.0088 16.4 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAG25197.1 - 0.0096 15.1 0.6 0.26 10.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAG25197.1 - 0.011 15.5 0.3 0.87 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OAG25197.1 - 0.013 15.7 0.1 2.8 8.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 OAG25197.1 - 0.014 15.2 0.1 0.38 10.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 OAG25197.1 - 0.017 14.9 0.2 7.8 6.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain SR-25 PF10500.9 OAG25197.1 - 0.018 14.6 2.0 0.035 13.7 2.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 OAG25197.1 - 0.025 14.8 0.1 8.2 7.0 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat DUF3584 PF12128.8 OAG25197.1 - 0.034 11.7 1.3 2.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.6 OAG25197.1 - 0.039 13.6 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG25197.1 - 0.042 14.3 0.0 10 6.5 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAG25197.1 - 0.046 13.0 0.0 3.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 OAG25197.1 - 0.056 13.5 0.0 8.1 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAG25197.1 - 0.059 12.5 0.0 4.6 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 OAG25197.1 - 0.069 12.4 1.9 0.96 8.7 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin Ploopntkinase3 PF18751.1 OAG25197.1 - 0.079 12.9 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PIN7 PF18475.1 OAG25197.1 - 0.08 13.6 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 PIN domain Arf PF00025.21 OAG25197.1 - 0.095 12.1 0.1 1.6 8.1 0.0 2.6 3 0 0 3 3 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.25 OAG25197.1 - 0.1 12.2 0.1 16 5.1 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 OAG25197.1 - 0.15 12.0 0.2 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 OAG25197.1 - 0.18 11.6 0.3 24 4.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal HEAT_EZ PF13513.6 OAG25197.1 - 0.23 12.0 1.0 43 4.8 0.0 3.2 2 1 0 2 2 2 0 HEAT-like repeat SRR1 PF07985.12 OAG25198.1 - 3.3e-07 30.2 0.0 6.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SRR1 PCP_red PF08369.10 OAG25198.1 - 0.0012 19.0 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit DUF4035 PF13227.6 OAG25198.1 - 0.12 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) zf-C2H2 PF00096.26 OAG25200.1 - 2.7e-09 37.0 10.3 0.0003 21.1 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG25200.1 - 7.9e-06 26.1 10.5 1.6e-05 25.1 1.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG25200.1 - 6.8e-05 23.4 9.4 0.1 13.5 1.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG25200.1 - 0.013 15.5 0.9 0.013 15.5 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAG25200.1 - 0.014 15.7 3.8 0.079 13.4 1.8 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Peptidase_S49_N PF08496.10 OAG25200.1 - 0.047 13.8 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zn-ribbon_8 PF09723.10 OAG25200.1 - 0.32 11.1 2.6 5 7.3 0.3 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 OAG25200.1 - 0.41 10.6 6.2 0.34 10.9 1.5 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Rpr2 PF04032.16 OAG25200.1 - 0.91 9.8 7.8 0.15 12.3 1.0 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HET PF06985.11 OAG25202.1 - 3e-12 47.1 12.2 7.4e-10 39.4 12.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ig_2 PF13895.6 OAG25202.1 - 0.048 14.0 0.1 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Pyrid_oxidase_2 PF13883.6 OAG25203.1 - 1.6e-50 171.4 0.0 1.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.14 OAG25204.1 - 1.4e-29 102.0 8.5 1.5e-29 101.9 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1687 PF07955.11 OAG25206.1 - 2.2e-28 99.3 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) RRM_1 PF00076.22 OAG25207.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cobW PF02492.19 OAG25208.1 - 3.4e-33 114.7 0.0 4.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAG25208.1 - 2e-06 27.0 0.1 0.00058 18.9 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OAG25208.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG25208.1 - 0.015 15.9 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAG25208.1 - 0.035 14.0 0.3 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 OAG25208.1 - 0.067 13.2 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OAG25208.1 - 0.098 12.4 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 OAG25208.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 OAG25208.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 OAG25208.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 OAG25208.1 - 0.14 11.9 0.1 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG25208.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_4 PF13894.6 OAG25209.1 - 0.66 11.0 5.6 0.33 11.9 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger NAD_binding_4 PF07993.12 OAG25212.1 - 7.3e-68 228.5 0.0 1.6e-67 227.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 OAG25212.1 - 1.3e-65 221.7 0.0 1.8e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG25212.1 - 3.6e-09 36.8 0.0 1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAG25212.1 - 4.1e-07 29.7 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 OAG25212.1 - 6.7e-06 27.0 0.0 8e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OAG25212.1 - 6e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG25212.1 - 0.046 13.6 0.0 0.47 10.3 0.0 2.5 1 1 0 1 1 1 0 NAD(P)H-binding Pinin_SDK_N PF04697.13 OAG25213.1 - 0.4 11.3 3.2 14 6.3 0.3 2.5 2 1 0 2 2 2 0 pinin/SDK conserved region ADH_zinc_N PF00107.26 OAG25214.1 - 1.7e-22 79.8 0.5 2.8e-22 79.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG25214.1 - 5.3e-16 59.9 0.0 1.1e-15 58.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG25214.1 - 7.2e-10 38.7 0.0 3.6e-08 33.2 0.0 3.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG25214.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF3277 PF11681.8 OAG25214.1 - 0.11 12.5 0.5 0.19 11.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3277) Fungal_trans_2 PF11951.8 OAG25215.1 - 1.7e-07 30.4 3.4 4.7e-07 29.0 3.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain LysM PF01476.20 OAG25216.1 - 9.1e-11 41.7 0.2 0.0099 15.9 0.0 3.3 3 0 0 3 3 3 3 LysM domain COesterase PF00135.28 OAG25217.1 - 2.9e-69 234.3 2.8 8.6e-69 232.7 2.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG25217.1 - 7.7e-05 22.3 0.1 0.00015 21.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG25217.1 - 0.0019 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold CFEM PF05730.11 OAG25218.1 - 2.7e-14 53.0 10.3 2.7e-14 53.0 10.3 1.7 2 0 0 2 2 2 1 CFEM domain FAD_binding_4 PF01565.23 OAG25219.1 - 3.8e-22 78.5 3.5 8.6e-22 77.4 3.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG25219.1 - 8.5e-13 48.2 1.4 1.8e-12 47.1 1.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG25219.1 - 0.033 13.6 0.3 0.061 12.7 0.3 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3787 PF12655.7 OAG25219.1 - 0.073 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) IBR PF01485.21 OAG25220.1 - 4.8e-09 36.3 27.4 5.3e-06 26.6 9.7 2.7 2 1 0 3 3 3 2 IBR domain, a half RING-finger domain PBP1_TM PF14812.6 OAG25220.1 - 0.19 12.1 8.2 0.48 10.8 8.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAG25220.1 - 4.9 5.1 7.2 6.8 4.7 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_4 PF13637.6 OAG25221.1 - 0.0044 17.6 0.0 0.047 14.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RabGAP-TBC PF00566.18 OAG25222.1 - 1.9e-48 165.0 1.9 1e-47 162.6 0.3 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain NOA36 PF06524.12 OAG25222.1 - 0.16 11.3 14.2 0.3 10.4 14.2 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4472 PF14739.6 OAG25222.1 - 0.17 12.6 20.0 0.79 10.5 12.3 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) Cnn_1N PF07989.11 OAG25222.1 - 0.2 11.8 24.9 0.061 13.5 10.5 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 PspB PF06667.12 OAG25222.1 - 0.37 10.9 7.0 0.36 10.9 1.9 2.7 2 0 0 2 2 2 0 Phage shock protein B DASH_Dam1 PF08653.10 OAG25222.1 - 0.4 10.5 6.1 14 5.6 0.2 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 YabA PF06156.13 OAG25222.1 - 2.8 8.6 21.0 8.6 7.1 4.3 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Mago_nashi PF02792.14 OAG25222.1 - 4.6 7.3 5.8 0.99 9.5 1.3 2.0 1 1 1 2 2 2 0 Mago nashi protein Fez1 PF06818.15 OAG25222.1 - 5.7 7.3 27.5 0.52 10.7 21.4 2.2 2 0 0 2 2 2 0 Fez1 Noelin-1 PF12308.8 OAG25222.1 - 6.6 6.8 10.3 0.65 10.0 3.0 2.7 2 1 1 3 3 3 0 Neurogenesis glycoprotein Glyco_hydro_61 PF03443.14 OAG25224.1 - 2.7e-48 164.7 0.1 4.5e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG25224.1 - 1.3e-11 44.2 7.7 1.3e-11 44.2 7.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain CENP-S PF15630.6 OAG25226.1 - 5.8e-34 116.3 0.0 7.3e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG25226.1 - 5.4e-08 32.9 0.0 7.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OAG25226.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 OAG25226.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OAG25226.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PGA2 PF07543.12 OAG25227.1 - 6.3e-18 65.1 0.1 7.1e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 ELF PF03317.13 OAG25227.1 - 0.073 13.1 0.0 0.076 13.0 0.0 1.1 1 0 0 1 1 1 0 ELF protein Tautomerase_3 PF14832.6 OAG25228.1 - 6.7e-08 32.8 0.1 2.6e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme CAP_N PF01213.19 OAG25229.1 - 9.5e-07 28.6 11.2 9.5e-07 28.6 11.2 3.2 4 0 0 4 4 4 1 Adenylate cyclase associated (CAP) N terminal WH2 PF02205.20 OAG25229.1 - 0.55 10.1 0.0 0.55 10.1 0.0 2.3 3 0 0 3 3 3 0 WH2 motif L51_S25_CI-B8 PF05047.16 OAG25231.1 - 4e-17 61.9 0.1 5.9e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SART-1 PF03343.13 OAG25232.1 - 7e-175 583.2 74.9 1.1e-174 582.6 74.9 1.3 1 0 0 1 1 1 1 SART-1 family CH_2 PF06294.11 OAG25232.1 - 0.14 12.3 1.8 0.51 10.5 0.4 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein HET PF06985.11 OAG25233.1 - 0.00065 20.1 0.4 0.00098 19.5 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box_5 PF18511.1 OAG25233.1 - 0.013 15.1 0.6 0.029 14.0 0.6 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAG25233.1 - 0.015 15.2 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAG25233.1 - 0.058 13.3 0.9 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 F-box domain DJ-1_PfpI PF01965.24 OAG25234.1 - 2.5e-16 59.9 0.0 4e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family cpYpsA PF12694.7 OAG25234.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family MFS_1 PF07690.16 OAG25235.1 - 3.2e-36 125.0 11.3 3.2e-36 125.0 11.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25235.1 - 3.4e-15 55.9 2.2 3.4e-15 55.9 2.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG25235.1 - 3.4e-05 22.9 5.0 3.4e-05 22.9 5.0 2.7 2 2 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 OAG25235.1 - 0.00048 18.8 10.9 0.18 10.3 3.5 3.4 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_4 PF06779.14 OAG25235.1 - 0.0011 18.4 4.7 0.0034 16.7 0.3 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Folate_carrier PF01770.18 OAG25235.1 - 0.039 12.7 0.0 0.073 11.8 0.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF2530 PF10745.9 OAG25235.1 - 0.33 11.2 3.3 0.4 10.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) LtrA PF06772.11 OAG25236.1 - 6.9e-24 84.7 18.7 6.9e-24 84.7 18.7 1.6 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Zip PF02535.22 OAG25236.1 - 0.0041 16.4 0.2 0.0041 16.4 0.2 2.1 3 0 0 3 3 3 1 ZIP Zinc transporter CcmD PF04995.14 OAG25236.1 - 0.49 10.5 4.5 4.6 7.4 0.3 3.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) TMEM125 PF15109.6 OAG25236.1 - 3.1 8.2 8.2 4.2 7.7 1.9 2.6 2 0 0 2 2 2 0 TMEM125 protein family DUF4293 PF14126.6 OAG25236.1 - 3.5 7.9 17.3 0.24 11.7 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) Flu_NP PF00506.18 OAG25237.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Suf PF05843.14 OAG25237.1 - 5.5 6.9 8.1 14 5.5 0.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Methyltransf_3 PF01596.17 OAG25238.1 - 3.1e-33 114.7 0.0 3.9e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG25238.1 - 8.1e-13 49.3 0.1 1.4e-12 48.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG25238.1 - 4.7e-06 26.6 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG25238.1 - 4.8e-05 23.2 0.0 7.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG25238.1 - 0.0009 19.9 0.0 0.0023 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG25238.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG25238.1 - 0.0044 16.4 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CmcI PF04989.12 OAG25238.1 - 0.0068 16.1 0.0 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_15 PF09445.10 OAG25238.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 OAG25238.1 - 0.013 16.2 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 OAG25238.1 - 0.014 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG25238.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrmK PF04816.12 OAG25238.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_23 PF13489.6 OAG25238.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain TFR_dimer PF04253.15 OAG25239.1 - 5.4e-23 81.4 0.0 9.7e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG25239.1 - 1.9e-20 73.4 0.0 3.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG25239.1 - 8.2e-09 35.4 0.2 8.2e-09 35.4 0.2 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 OAG25239.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MAT1 PF06391.13 OAG25239.1 - 0.22 11.4 0.2 0.33 10.8 0.2 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 GAS2 PF02187.17 OAG25240.1 - 3.3e-06 27.1 0.1 7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain RINGv PF12906.7 OAG25241.1 - 5e-10 39.3 4.5 1.9e-09 37.5 1.5 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 OAG25241.1 - 0.045 14.1 4.7 1.1 9.7 1.4 2.2 2 0 0 2 2 2 0 Ring finger domain zf-BED PF02892.15 OAG25241.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.1 2 0 0 2 2 2 0 BED zinc finger PHD PF00628.29 OAG25241.1 - 0.34 10.8 5.2 0.17 11.8 2.5 1.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 OAG25241.1 - 0.5 10.5 6.3 2.1 8.5 2.9 2.2 1 1 1 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 OAG25241.1 - 2.4 8.0 5.3 0.75 9.6 1.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Proteasome PF00227.26 OAG25242.1 - 2.6e-40 137.9 0.1 8.2e-22 77.6 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit Ribonuclease_3 PF00636.26 OAG25243.1 - 1e-35 122.5 0.0 1.9e-16 60.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OAG25243.1 - 7.3e-22 77.3 0.0 2e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OAG25243.1 - 3.2e-21 75.8 0.0 3.9e-09 36.8 0.0 3.8 2 1 1 3 3 3 3 Ribonuclease-III-like DEAD PF00270.29 OAG25243.1 - 5.6e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG25243.1 - 7.4e-14 52.0 0.0 1.8e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG25243.1 - 3.8e-11 43.3 0.0 8.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit C2 PF00168.30 OAG25245.1 - 2.2e-29 101.7 0.0 1.8e-17 63.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain Amidohydro_3 PF07969.11 OAG25246.1 - 9.1e-08 32.0 0.4 0.00012 21.7 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 OAG25246.1 - 1.6e-07 31.0 0.0 3.3e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family ADK PF00406.22 OAG25247.1 - 5.3e-15 55.8 0.0 5.6e-14 52.5 0.0 1.9 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG25247.1 - 4.7e-13 49.7 0.0 1.7e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG25247.1 - 1e-05 26.1 0.0 3.2e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG25247.1 - 0.0021 18.2 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OAG25247.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 OAG25247.1 - 0.0091 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 OAG25247.1 - 0.03 14.6 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 OAG25247.1 - 0.032 14.5 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAG25247.1 - 0.05 13.7 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG25247.1 - 0.061 13.7 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 OAG25247.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 OAG25247.1 - 0.093 12.0 0.0 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 OAG25247.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 OAG25247.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 OAG25247.1 - 0.2 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 OAG25247.1 - 0.23 11.1 0.0 8.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase GDI PF00996.18 OAG25248.1 - 1.6e-25 89.5 0.0 6.5e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor DS PF01916.17 OAG25248.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase Aminotran_1_2 PF00155.21 OAG25250.1 - 1e-70 238.7 0.0 1.2e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG25250.1 - 0.0002 20.8 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG25250.1 - 0.0012 17.9 0.0 0.0033 16.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG25250.1 - 0.0026 16.4 0.1 0.0061 15.1 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAG25250.1 - 0.0035 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase MgsA_C PF12002.8 OAG25251.1 - 3.7e-60 202.6 0.0 6.8e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OAG25251.1 - 1.5e-23 82.9 0.2 3.6e-23 81.7 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OAG25251.1 - 2.7e-15 57.0 0.1 7.2e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG25251.1 - 1.6e-07 31.2 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG25251.1 - 2.2e-06 28.2 0.4 0.0019 18.6 0.1 3.0 1 1 2 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OAG25251.1 - 2.4e-05 24.6 0.1 6.2e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAG25251.1 - 4.4e-05 23.0 0.1 0.048 13.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG25251.1 - 5.3e-05 23.2 0.1 0.00026 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG25251.1 - 0.00017 21.3 0.0 0.0035 17.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 OAG25251.1 - 0.00031 20.0 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG25251.1 - 0.00036 20.6 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAG25251.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAG25251.1 - 0.0018 18.2 0.1 0.34 10.8 0.0 2.7 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea SKI PF01202.22 OAG25251.1 - 0.0023 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Arm_2 PF04826.13 OAG25251.1 - 0.02 14.4 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Armadillo-like TIP49 PF06068.13 OAG25251.1 - 0.021 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OAG25251.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG25251.1 - 0.024 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 OAG25251.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAG25251.1 - 0.024 13.9 0.0 0.073 12.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 OAG25251.1 - 0.036 14.1 0.3 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 OAG25251.1 - 0.048 14.2 0.0 0.1 13.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TRAF6_Z2 PF18048.1 OAG25251.1 - 0.074 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 TniB PF05621.11 OAG25251.1 - 0.078 12.4 0.0 0.23 10.8 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 OAG25251.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 OAG25251.1 - 0.097 12.9 0.2 0.31 11.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG25251.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAG25251.1 - 0.11 12.2 0.1 0.55 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG25251.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 OAG25251.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG25251.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PHD PF00628.29 OAG25252.1 - 6.4e-06 26.0 10.2 1.2e-05 25.1 10.2 1.5 1 0 0 1 1 1 1 PHD-finger Diphthamide_syn PF01866.17 OAG25253.1 - 3.2e-111 371.6 0.0 4.1e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Sulf_transp PF04143.14 OAG25254.1 - 6.2e-06 26.0 6.4 6.2e-06 26.0 6.4 3.3 1 1 1 3 3 3 3 Sulphur transport MHYT PF03707.16 OAG25254.1 - 1 9.6 8.2 2.1 8.6 0.6 3.1 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat F-box-like_2 PF13013.6 OAG25255.1 - 0.02 14.9 0.9 0.041 13.9 0.1 1.8 2 0 0 2 2 2 0 F-box-like domain His_Phos_1 PF00300.22 OAG25256.1 - 1.2e-27 96.9 0.0 3e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OAG25256.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.12 OAG25257.1 - 2e-37 128.1 20.6 4.7e-37 126.8 20.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 OAG25257.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic Hid1 PF12722.7 OAG25257.1 - 2.3 6.2 5.5 2.4 6.2 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XRN_M PF17846.1 OAG25257.1 - 3.9 6.3 10.1 6 5.7 10.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Vma12 PF11712.8 OAG25257.1 - 4.4 7.4 4.9 6.9 6.7 4.9 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3551 PF12071.8 OAG25259.1 - 0.33 11.0 2.8 0.86 9.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) Zn_clus PF00172.18 OAG25260.1 - 0.0079 16.3 4.1 0.6 10.3 1.0 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase PF03211.13 OAG25261.1 - 2.7e-87 291.6 12.8 3.1e-87 291.4 12.8 1.0 1 0 0 1 1 1 1 Pectate lyase zf-RING_2 PF13639.6 OAG25262.1 - 3.3e-08 33.7 6.7 6.6e-08 32.8 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG25262.1 - 5e-05 23.1 6.4 8.9e-05 22.3 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG25262.1 - 0.00011 22.0 5.4 0.00019 21.2 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG25262.1 - 0.00016 21.6 1.6 0.00034 20.6 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG25262.1 - 0.00042 20.5 4.6 0.00091 19.5 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG25262.1 - 0.00046 20.0 6.9 0.0011 18.8 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG25262.1 - 0.0011 19.0 4.8 0.0022 18.0 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OAG25262.1 - 0.0036 17.0 3.9 0.0066 16.2 3.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAG25262.1 - 0.031 14.2 6.5 0.056 13.4 6.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG25262.1 - 0.2 11.6 4.5 0.43 10.5 4.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAG25262.1 - 1.9 8.3 7.2 4.4 7.2 7.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 OAG25262.1 - 2.2 8.3 7.5 4.8 7.1 7.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG25263.1 - 7.4e-10 39.0 9.9 1.2e-09 38.3 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG25263.1 - 0.00038 20.4 6.8 0.00072 19.5 6.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OAG25263.1 - 0.00066 19.4 4.9 0.0015 18.2 5.0 1.7 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAG25263.1 - 0.0009 19.1 10.1 0.0015 18.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG25263.1 - 0.0065 16.4 8.1 0.011 15.6 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG25263.1 - 0.0073 16.1 8.1 0.012 15.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG25263.1 - 0.011 15.5 5.5 0.034 13.9 5.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 OAG25263.1 - 0.019 14.8 9.6 0.042 13.7 9.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG25263.1 - 0.17 12.2 8.3 0.38 11.1 8.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3552 PF12072.8 OAG25263.1 - 0.3 10.5 5.6 0.5 9.7 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-C3HC4_5 PF17121.5 OAG25263.1 - 0.94 9.4 6.9 3.8 7.5 7.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG25263.1 - 1.9 8.7 6.8 8.2 6.7 6.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAG25263.1 - 3.6 7.8 6.0 7.5 6.8 6.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OAG25263.1 - 7.8 6.5 11.3 1.5 8.8 3.7 2.3 1 1 0 2 2 2 0 Prokaryotic RING finger family 4 Aft1_HRA PF11786.8 OAG25264.1 - 2e-21 76.1 9.2 2e-21 76.1 9.2 2.9 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.8 OAG25264.1 - 3e-17 63.6 9.4 3e-17 63.6 9.4 4.0 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 OAG25264.1 - 3.4e-16 59.4 13.6 2.7e-15 56.5 9.9 3.4 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 OAG25264.1 - 8.7e-13 48.2 5.3 2e-12 47.0 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG25264.1 - 2.7e-05 24.2 5.7 6.8e-05 22.9 5.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG25264.1 - 0.0069 16.9 3.2 0.0069 16.9 3.2 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor Transthyretin PF00576.21 OAG25266.1 - 3.6e-35 121.0 0.0 4.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Opy2 PF09463.10 OAG25267.1 - 1.5e-06 28.4 17.6 3.1e-06 27.4 17.6 1.6 1 0 0 1 1 1 1 Opy2 protein F-box PF00646.33 OAG25268.1 - 0.00016 21.4 0.2 0.00057 19.7 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG25268.1 - 0.0002 21.2 0.1 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 OAG25268.1 - 0.00097 19.0 0.3 0.0028 17.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF2373 PF10180.9 OAG25269.1 - 4.9e-21 74.3 0.0 8.9e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 OAG25270.1 - 2.1e-51 174.1 0.0 2.9e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG25270.1 - 5.1e-13 48.4 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 OAG25270.1 - 0.088 12.7 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF2384 PF09722.10 OAG25271.1 - 0.24 11.5 1.3 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) Ribosomal_L35Ae PF01247.18 OAG25273.1 - 2.3e-38 130.3 0.1 2.6e-38 130.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAG25273.1 - 0.0024 18.0 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain CDC27 PF09507.10 OAG25276.1 - 0.0039 16.6 28.8 0.0039 16.6 28.8 2.7 2 1 0 2 2 2 2 DNA polymerase subunit Cdc27 Nrap_D5 PF17406.2 OAG25276.1 - 1 9.1 4.1 3.6 7.3 4.1 2.0 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 vATP-synt_AC39 PF01992.16 OAG25277.1 - 4.8e-106 355.0 0.0 5.4e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF1007 PF06226.13 OAG25280.1 - 0.036 14.0 0.0 0.04 13.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1007) Trehalase PF01204.18 OAG25281.1 - 1.2e-194 647.9 0.0 1.5e-194 647.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAG25281.1 - 5.8e-16 57.9 0.6 9.6e-16 57.2 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GH-E PF14410.6 OAG25281.1 - 0.051 14.0 1.3 0.62 10.5 0.0 3.1 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues OCRE PF17780.1 OAG25281.1 - 0.055 13.5 0.3 0.17 11.9 0.3 1.9 1 0 0 1 1 1 0 OCRE domain DUF5643 PF18705.1 OAG25281.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Ctf8 PF09696.10 OAG25282.1 - 1.7e-40 138.7 0.3 1e-39 136.1 0.3 1.8 1 1 0 1 1 1 1 Ctf8 CBM_1 PF00734.18 OAG25283.1 - 1.7e-11 43.8 8.1 1.7e-11 43.8 8.1 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Trypan_PARP PF05887.11 OAG25283.1 - 0.0076 16.2 0.2 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NUDIX PF00293.28 OAG25285.1 - 3e-12 46.7 0.2 2.1e-10 40.7 0.0 2.3 1 1 1 2 2 2 2 NUDIX domain p450 PF00067.22 OAG25286.1 - 3.9e-66 223.7 0.0 5.2e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.6 OAG25287.1 - 4.2e-15 56.6 0.1 6.7e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG25287.1 - 5.7e-06 26.4 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HSP9_HSP12 PF04119.12 OAG25288.1 - 1.6 9.2 3.7 57 4.2 0.0 3.6 4 0 0 4 4 4 0 Heat shock protein 9/12 Aminotran_3 PF00202.21 OAG25289.1 - 9.5e-112 373.6 0.0 1.2e-111 373.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG25289.1 - 5.6e-07 29.1 0.0 1.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II SNF2_N PF00176.23 OAG25290.1 - 3.3e-42 144.4 0.0 3.3e-41 141.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG25290.1 - 1.8e-06 28.3 0.1 4.8e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG25290.1 - 0.013 15.5 0.0 7.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Toprim_2 PF13155.6 OAG25290.1 - 0.16 12.4 0.1 0.9 10.0 0.0 2.2 2 0 0 2 2 2 0 Toprim-like adh_short PF00106.25 OAG25291.1 - 1.8e-27 96.1 0.9 6.3e-16 58.4 0.1 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25291.1 - 1.8e-21 76.8 2.0 1.3e-12 47.8 0.0 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25291.1 - 5.6e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Ala_racemase_N PF01168.20 OAG25294.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 OAG25294.1 - 3.8e-20 72.3 0.0 7.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain DUF1533 PF07550.11 OAG25294.1 - 0.0043 16.9 0.1 0.043 13.7 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1533) Glyco_hydro_16 PF00722.21 OAG25295.1 - 4e-16 59.0 1.5 6e-16 58.4 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mpv17_PMP22 PF04117.12 OAG25296.1 - 3.8e-14 52.7 1.4 8.1e-14 51.6 1.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family HET PF06985.11 OAG25297.1 - 7.9e-27 94.4 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ipi1_N PF12333.8 OAG25298.1 - 8.8e-26 90.5 0.5 8.8e-26 90.5 0.5 2.3 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Sigma70_r4_2 PF08281.12 OAG25298.1 - 0.021 14.5 0.3 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Robl_LC7 PF03259.17 OAG25299.1 - 1.1e-09 38.0 0.0 1.6e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain FAM219A PF15260.6 OAG25299.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein family FAM219A DUF1348 PF07080.11 OAG25300.1 - 9.6e-61 203.4 6.1 1.1e-60 203.2 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAG25300.1 - 7.7e-07 29.7 0.0 1e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG25300.1 - 8.1e-05 23.0 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 OAG25300.1 - 0.049 13.4 0.0 0.093 12.5 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Redoxin PF08534.10 OAG25301.1 - 1.8e-35 121.8 0.0 2.1e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG25301.1 - 2.9e-09 36.9 0.0 3.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family ARPC4 PF05856.12 OAG25302.1 - 4.4e-77 257.4 4.5 4.9e-77 257.2 4.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 OAG25303.1 - 1.5e-52 178.6 0.0 2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAG25303.1 - 2e-13 49.8 0.8 4.7e-13 48.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.6 OAG25303.1 - 3.2e-12 46.7 6.9 1.6e-11 44.4 5.5 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 OAG25303.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad21_Rec8_N PF04825.13 OAG25304.1 - 5.3e-27 94.2 0.0 9.5e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAG25304.1 - 0.0077 15.5 0.0 0.018 14.3 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein His_Phos_2 PF00328.22 OAG25305.1 - 2.7e-39 135.6 0.0 3.2e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tyrosinase PF00264.20 OAG25306.1 - 5.4e-37 128.2 0.1 1e-36 127.3 0.1 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase SP24 PF16504.5 OAG25307.1 - 0.042 13.9 0.6 0.083 12.9 0.6 1.4 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus adh_short_C2 PF13561.6 OAG25309.1 - 3.9e-41 141.2 0.4 2.8e-38 131.8 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG25309.1 - 1.9e-40 138.4 0.0 2.3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG25309.1 - 7.7e-11 42.2 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG25309.1 - 0.012 15.0 0.2 0.075 12.5 0.2 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG25311.1 - 4.2e-27 94.9 0.0 5.2e-20 71.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25311.1 - 1.4e-14 54.3 0.0 1.1e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25311.1 - 1.6e-09 38.0 0.0 2.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG25311.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG25311.1 - 0.024 13.8 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG25311.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF262 PF03235.14 OAG25312.1 - 1.9e-15 57.6 0.0 4.9e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 Cupin_2 PF07883.11 OAG25313.1 - 7.8e-16 57.6 0.6 5.4e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG25313.1 - 2.9e-10 40.2 0.2 0.00048 20.1 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG25313.1 - 1.4e-08 34.3 0.6 3.1e-05 23.6 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_4 PF08007.12 OAG25313.1 - 0.00052 19.6 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 OAG25313.1 - 0.0033 17.0 0.7 0.0092 15.6 0.2 1.9 2 1 1 3 3 3 1 Cupin MannoseP_isomer PF01050.18 OAG25313.1 - 0.014 15.3 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 OAG25313.1 - 0.095 12.9 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Mif2/CENP-C like NUC173 PF08161.12 OAG25314.1 - 8.9e-82 273.7 0.1 6.2e-77 257.9 0.0 3.0 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.22 OAG25314.1 - 0.083 13.2 0.1 84 3.8 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OAG25314.1 - 0.13 12.9 0.4 12 6.5 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region VSG_B PF13206.6 OAG25314.1 - 0.14 11.4 11.0 0.05 12.9 4.5 2.4 2 0 0 2 2 2 0 Trypanosomal VSG domain TFCD_C PF12612.8 OAG25314.1 - 0.42 10.4 2.1 9.8 6.0 0.1 4.0 4 2 0 4 4 4 0 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OAG25314.1 - 1.8 9.0 6.1 7.8 7.0 0.5 4.1 4 0 0 4 4 4 0 HEAT repeats DOCK_N PF16172.5 OAG25315.1 - 3.4e-110 368.5 0.1 3.4e-110 368.5 0.1 1.8 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 OAG25315.1 - 6e-40 137.4 1.0 2.2e-39 135.5 1.0 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OAG25315.1 - 7.1e-34 117.3 0.0 1.7e-33 116.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 OAG25315.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG25315.1 - 0.0031 17.4 0.0 0.0098 15.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Ctr PF04145.15 OAG25316.1 - 1.1e-31 110.5 0.4 1.4e-31 110.1 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Vac7 PF12751.7 OAG25316.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Ribosomal_L30 PF00327.20 OAG25318.1 - 5.2e-15 55.1 0.3 6.9e-15 54.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MBOAT_2 PF13813.6 OAG25319.1 - 2.8e-22 78.8 2.5 3.1e-21 75.4 0.2 2.4 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family fn3_2 PF16893.5 OAG25320.1 - 3.9e-39 132.7 0.1 6.6e-39 132.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAG25320.1 - 2e-22 78.8 0.4 3.3e-22 78.2 0.4 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 OAG25320.1 - 1.6e-15 56.8 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OAG25320.1 - 5.5e-10 39.5 0.0 9.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 OAG25320.1 - 0.00034 20.8 0.9 0.00057 20.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAG25320.1 - 0.00063 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAG25320.1 - 0.00079 19.7 0.0 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain PPL4 PF18188.1 OAG25320.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Prim-pol 4 BRCT_3 PF18428.1 OAG25320.1 - 0.038 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1297 PF06973.12 OAG25320.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Glyco_hydro_63 PF03200.16 OAG25321.1 - 8.4e-07 28.1 6.6 2.4e-05 23.3 0.3 3.2 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Mob1_phocein PF03637.17 OAG25322.1 - 2.8e-72 242.2 0.0 3.5e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_45 PF02015.16 OAG25323.1 - 1.5e-53 181.9 13.6 1.9e-53 181.5 13.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 TMEM208_SND2 PF05620.11 OAG25324.1 - 4.3 7.1 5.1 0.59 9.9 0.5 1.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF1757 PF08560.10 OAG25325.1 - 1.8e-05 24.8 0.0 2.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Gly-zipper_Omp PF13488.6 OAG25325.1 - 1.7 8.7 20.1 7.7 6.6 15.1 2.3 2 0 0 2 2 2 0 Glycine zipper Coiled PF05710.12 OAG25326.1 - 0.26 12.2 10.3 0.12 13.2 6.7 1.9 1 1 1 2 2 2 0 Coiled coil PIR PF00399.19 OAG25327.1 - 7.4e-32 108.2 77.4 4.7e-06 26.0 4.9 8.3 5 2 3 8 8 8 7 Yeast PIR protein repeat DUF281 PF03436.13 OAG25327.1 - 0.66 10.4 2.9 5.5 7.5 0.3 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF281) Arf PF00025.21 OAG25328.1 - 9.5e-66 220.5 0.0 1.1e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAG25328.1 - 3e-12 46.4 0.0 9.8e-09 34.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAG25328.1 - 3.2e-08 33.2 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG25328.1 - 5.8e-08 33.0 0.0 1.7e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG25328.1 - 1.7e-07 31.3 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG25328.1 - 9.1e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG25328.1 - 1.4e-05 24.6 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG25328.1 - 0.036 13.6 0.0 1 8.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain mRNA_decap_C PF16741.5 OAG25328.1 - 0.11 11.8 0.2 0.65 9.3 0.1 2.0 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus cobW PF02492.19 OAG25328.1 - 0.14 11.7 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAG25328.1 - 0.22 11.3 0.0 0.81 9.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mt_ATP-synt_D PF05873.12 OAG25329.1 - 1.7e-21 76.7 0.9 2.2e-21 76.3 0.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) KASH_CCD PF14662.6 OAG25329.1 - 0.00065 19.6 2.2 0.48 10.2 0.0 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF148 PF02520.17 OAG25329.1 - 0.01 15.9 3.6 0.01 15.9 3.6 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 OAG25329.1 - 0.039 14.0 4.4 1.9 8.6 1.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2408 PF10303.9 OAG25329.1 - 0.18 12.4 1.5 0.26 11.8 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) NusB PF01029.18 OAG25329.1 - 0.19 12.0 2.6 0.45 10.7 0.4 2.0 1 1 1 2 2 2 0 NusB family ADIP PF11559.8 OAG25329.1 - 0.24 11.5 4.1 0.32 11.1 1.6 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 OAG25329.1 - 0.36 11.3 5.8 1.6 9.3 1.4 2.4 1 1 2 3 3 3 0 Spectrin repeat APG6_N PF17675.1 OAG25329.1 - 1.3 9.5 4.8 2.9 8.4 4.7 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Nup35_RRM PF05172.13 OAG25330.1 - 0.0042 17.0 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L14e PF01929.17 OAG25331.1 - 2e-28 98.6 2.1 6e-28 97.1 2.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAG25331.1 - 0.00012 21.9 0.1 0.00023 21.0 0.1 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.18 OAG25332.1 - 4.2e-23 81.1 0.0 1.7e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 NAC domain Myc_N PF01056.18 OAG25332.1 - 0.38 10.6 19.0 0.018 14.9 8.7 2.0 1 1 1 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 OAG25332.1 - 0.67 10.4 12.6 4.7 7.7 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PGA2 PF07543.12 OAG25332.1 - 0.98 9.4 15.3 5 7.1 0.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Imm27 PF15590.6 OAG25333.1 - 0.044 13.6 0.1 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 27 adh_short PF00106.25 OAG25334.1 - 6.4e-13 48.6 0.0 9.5e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25334.1 - 7.8e-12 45.2 0.1 2.1e-11 43.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP2C_2 PF13672.6 OAG25334.1 - 0.00074 19.2 0.1 0.0011 18.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_tran_WecB PF03808.13 OAG25334.1 - 0.1 12.6 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family TauD PF02668.16 OAG25335.1 - 2e-26 93.4 0.0 2.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 OAG25336.1 - 0.0048 17.0 5.1 0.01 15.9 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.7 OAG25337.1 - 0.00076 19.4 0.0 0.0037 17.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG25337.1 - 0.0049 17.1 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG25337.1 - 0.052 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 OAG25338.1 - 1.4e-24 86.7 0.1 5.8e-18 65.1 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase DUF2183 PF09949.9 OAG25338.1 - 9.8e-16 57.9 0.0 3.2e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short_C2 PF13561.6 OAG25338.1 - 4e-12 46.2 0.0 4.9e-08 32.8 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25338.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 KR domain Phage_GPL PF05926.11 OAG25338.1 - 0.11 12.5 1.7 0.33 11.0 0.5 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) LSM PF01423.22 OAG25339.1 - 1.2e-13 50.6 0.0 1.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG25339.1 - 0.18 12.0 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 Ataxin 2 SM domain Cellulase PF00150.18 OAG25341.1 - 1.2e-21 77.4 0.1 1.7e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG25341.1 - 2.3e-05 23.7 0.0 3.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 OAG25341.1 - 0.00083 19.1 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Transp_inhibit PF18791.1 OAG25341.1 - 0.022 14.2 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain Glyco_hydro_42 PF02449.15 OAG25341.1 - 0.051 12.9 0.1 0.21 10.9 0.2 1.8 2 0 0 2 2 2 0 Beta-galactosidase TFX_C PF14601.6 OAG25341.1 - 0.17 11.9 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term TPR_1 PF00515.28 OAG25343.1 - 7.4e-35 117.4 25.0 0.00039 20.1 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAG25343.1 - 2.7e-34 114.5 22.4 0.00021 21.2 0.0 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 OAG25343.1 - 1.3e-22 80.2 6.0 1.1e-05 25.9 0.3 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAG25343.1 - 5.6e-19 67.5 16.7 0.00017 21.2 0.0 8.4 7 1 1 8 8 8 6 TPR repeat TPR_8 PF13181.6 OAG25343.1 - 1.3e-17 62.5 19.9 0.024 14.9 0.1 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG25343.1 - 1.2e-15 56.7 11.8 0.0021 18.3 0.0 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG25343.1 - 3.2e-12 46.5 27.6 0.0013 19.0 1.1 9.0 3 2 7 10 10 10 6 Tetratricopeptide repeat TPR_9 PF13371.6 OAG25343.1 - 4.8e-10 39.4 9.3 0.00011 22.3 0.1 5.0 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG25343.1 - 1.7e-09 37.0 14.1 0.051 13.6 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG25343.1 - 5.1e-09 36.5 22.3 8.7e-06 26.2 0.3 6.4 5 1 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG25343.1 - 6.9e-09 35.8 17.2 0.032 15.0 0.3 7.6 6 3 3 9 9 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG25343.1 - 3.6e-08 33.5 9.4 0.0061 16.8 0.1 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OAG25343.1 - 5.7e-06 26.0 22.2 0.029 14.2 0.2 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG25343.1 - 1.4e-05 24.7 0.5 3.4e-05 23.4 0.1 1.8 2 1 0 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 OAG25343.1 - 3.2e-05 23.3 5.7 0.76 9.3 0.0 5.4 5 0 0 5 5 5 2 SHNi-TPR DUF3856 PF12968.7 OAG25343.1 - 0.0038 17.3 4.9 4.9 7.2 0.0 5.2 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 OAG25343.1 - 0.0053 17.3 12.2 13 6.7 0.5 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat RFX5_DNA_bdg PF14621.6 OAG25343.1 - 0.0069 16.2 4.0 0.013 15.3 4.0 1.4 1 0 0 1 1 1 1 RFX5 DNA-binding domain MAS20 PF02064.15 OAG25343.1 - 0.013 15.6 9.3 0.49 10.5 1.0 4.3 4 1 1 5 5 4 0 MAS20 protein import receptor Sel1 PF08238.12 OAG25343.1 - 0.016 15.9 2.2 1.7 9.5 0.0 4.0 3 0 0 3 3 3 0 Sel1 repeat HrpB1_HrpK PF09613.10 OAG25343.1 - 0.018 14.7 0.2 0.073 12.7 0.2 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TAF1_subA PF14929.6 OAG25343.1 - 0.053 12.9 1.0 0.2 11.1 0.1 2.2 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A DDHD PF02862.17 OAG25343.1 - 0.061 13.5 0.4 0.17 12.0 0.4 1.7 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 OAG25343.1 - 0.12 12.9 0.6 0.29 11.6 0.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 TPR_3 PF07720.12 OAG25343.1 - 2.5 8.2 11.4 26 5.0 0.5 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OAG25343.1 - 3.4 7.8 15.6 9.8 6.3 0.0 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 OAG25344.1 - 4.3e-75 252.5 0.0 5.7e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25344.1 - 3.6e-39 134.6 0.0 5.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAG25344.1 - 7.6e-18 65.1 0.0 7.6e-08 32.8 0.0 3.5 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 OAG25344.1 - 3.3e-17 62.3 0.1 6.5e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 OAG25344.1 - 2.8e-06 26.9 0.0 1.5e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG25344.1 - 0.0019 17.2 0.1 0.0036 16.3 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAG25344.1 - 0.0038 16.8 0.1 0.0095 15.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAG25344.1 - 0.0093 15.3 0.6 0.014 14.7 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG25344.1 - 0.016 15.1 0.2 0.1 12.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 OAG25344.1 - 0.21 10.4 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MFS_1 PF07690.16 OAG25345.1 - 1.2e-29 103.4 31.0 1.2e-29 103.4 31.0 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG25345.1 - 0.0045 16.7 3.7 0.01 15.6 3.7 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Amidase_5 PF05382.13 OAG25345.1 - 0.096 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Imm57 PF15596.6 OAG25345.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 57 LMWPc PF01451.21 OAG25347.1 - 3.6e-31 108.4 0.0 5.1e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.17 OAG25348.1 - 3.5e-75 251.5 0.5 5.5e-75 250.8 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG25348.1 - 5.5e-30 103.1 0.0 1.1e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG25348.1 - 2.7e-21 75.8 6.0 5.9e-18 64.8 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG25348.1 - 4.6e-08 33.2 10.8 4.4e-07 30.0 10.8 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG25348.1 - 0.0021 18.0 0.0 0.0044 16.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Tyrosinase PF00264.20 OAG25349.1 - 1.3e-50 172.8 0.4 2.3e-50 172.0 0.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.19 OAG25349.1 - 5e-19 68.7 0.2 2.2e-17 63.4 0.2 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG25349.1 - 0.0098 15.5 0.2 0.046 13.3 0.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG25349.1 - 0.036 13.3 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG25349.1 - 0.043 14.0 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAG25349.1 - 0.11 11.5 0.0 2.8 6.9 0.0 2.4 3 0 0 3 3 3 0 Squalene epoxidase TIC20 PF16166.5 OAG25350.1 - 0.057 13.2 2.5 0.08 12.7 2.5 1.2 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like DUF3455 PF11937.8 OAG25351.1 - 7.9e-33 114.1 0.1 1e-32 113.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PepSY_2 PF13670.6 OAG25351.1 - 0.86 9.7 2.7 8.2 6.5 0.5 2.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain p450 PF00067.22 OAG25352.1 - 5.4e-60 203.5 0.0 7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ten1 PF12658.7 OAG25353.1 - 5.4e-37 126.4 0.0 6e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 OAG25353.1 - 4.7e-09 36.0 0.0 6.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 OAG25353.1 - 2.9e-06 27.6 0.0 4.1e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Replication factor A protein 3 Snf7 PF03357.21 OAG25354.1 - 9e-41 139.3 17.8 9e-41 139.3 17.8 2.0 1 1 1 2 2 2 1 Snf7 DUF4483 PF14825.6 OAG25354.1 - 0.014 15.2 1.4 0.025 14.4 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) OrfB_IS605 PF01385.19 OAG25354.1 - 0.12 12.6 3.2 0.24 11.6 3.2 1.4 1 0 0 1 1 1 0 Probable transposase FidL_like PF15941.5 OAG25354.1 - 0.26 11.7 1.8 0.5 10.8 0.8 2.0 1 1 0 1 1 1 0 FidL-like putative membrane protein DUF3138 PF11336.8 OAG25354.1 - 1.4 7.5 3.7 2.2 6.8 3.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) PIN_8 PF18476.1 OAG25354.1 - 6.6 6.5 10.9 25 4.6 10.9 1.9 1 1 0 1 1 1 0 PIN like domain Forkhead PF00250.18 OAG25355.1 - 7.4e-25 87.0 0.2 1.7e-24 85.9 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG25355.1 - 9.1e-06 25.9 0.1 1.9e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.6 OAG25356.1 - 5.5e-08 33.6 0.0 1.4e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAG25356.1 - 0.024 15.1 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.8 OAG25357.1 - 2.5e-21 76.5 0.1 3.8e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 OAG25359.1 - 6.1e-29 101.1 30.3 7.7e-29 100.7 30.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily BTP PF05232.12 OAG25359.1 - 0.026 14.6 0.5 0.026 14.6 0.5 3.0 2 1 0 2 2 2 0 Chlorhexidine efflux transporter Peptidase_U4 PF03419.13 OAG25359.1 - 4.7 6.4 19.4 0.027 13.8 9.4 2.2 2 1 0 2 2 2 0 Sporulation factor SpoIIGA SRR1 PF07985.12 OAG25361.1 - 1e-10 41.5 0.1 2.9e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 SRR1 GST_N_2 PF13409.6 OAG25362.1 - 1.2e-20 73.6 0.0 2.4e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG25362.1 - 3.7e-15 55.7 0.0 8.8e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG25362.1 - 5.5e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG25362.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG25362.1 - 0.074 13.5 0.0 0.61 10.5 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAG25362.1 - 0.086 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAG25362.1 - 0.16 11.7 0.1 0.45 10.4 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidohydro_1 PF01979.20 OAG25363.1 - 5e-18 65.5 0.6 2e-17 63.5 0.6 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG25363.1 - 3.2e-12 46.7 1.6 1.4e-07 31.4 0.0 2.7 1 1 2 3 3 3 2 Amidohydrolase family FYVE PF01363.21 OAG25365.1 - 0.0025 17.9 4.1 0.0025 17.9 4.1 2.9 3 1 0 3 3 3 1 FYVE zinc finger IBR PF01485.21 OAG25365.1 - 0.72 10.1 8.8 3.1 8.1 0.1 3.1 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Fungal_trans PF04082.18 OAG25366.1 - 1.3e-19 70.3 0.4 1.3e-19 70.3 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG25366.1 - 9.2e-16 57.7 22.7 1.3e-08 34.8 9.4 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG25367.1 - 7.4e-72 242.6 21.0 8.4e-72 242.5 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG25367.1 - 3.8e-13 49.1 35.2 3.8e-13 49.1 35.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.23 OAG25368.1 - 2.8e-63 214.1 0.0 4e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG25368.1 - 5e-21 74.9 5.7 4.3e-20 71.9 5.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OAG25368.1 - 6.5e-05 22.7 0.1 0.055 13.0 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_44 PF12891.7 OAG25368.1 - 0.027 14.4 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Glycoside hydrolase family 44 DUF229 PF02995.17 OAG25368.1 - 0.15 10.6 0.0 0.29 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) APG6_N PF17675.1 OAG25369.1 - 0.012 16.1 4.2 0.012 16.1 4.2 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF573 PF04504.14 OAG25369.1 - 0.039 14.6 1.7 4.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Thioredoxin PF00085.20 OAG25370.1 - 2.5e-28 98.1 0.1 3.2e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG25370.1 - 1.7e-08 34.6 0.0 9.3e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG25370.1 - 1.5e-07 31.9 0.2 7.4e-07 29.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAG25370.1 - 5e-06 26.4 0.1 0.0045 16.9 0.1 2.2 1 1 1 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 OAG25370.1 - 8.7e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 OAG25370.1 - 0.00011 21.9 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OAG25370.1 - 0.00051 19.8 0.3 0.75 9.5 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 OAG25370.1 - 0.00057 20.0 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OAG25370.1 - 0.0028 17.5 0.1 0.0042 16.9 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 OAG25370.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_C69 PF03577.15 OAG25371.1 - 3.1e-21 75.8 0.0 5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C69 Peptidase_S58 PF03576.14 OAG25372.1 - 2.7e-112 375.2 0.0 3.2e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 Soyouz_module PF14313.6 OAG25372.1 - 0.082 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) HMG_box PF00505.19 OAG25373.1 - 1.4e-09 38.2 0.8 4.2e-09 36.7 0.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 OAG25373.1 - 1.6e-07 31.7 0.0 5.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAG25373.1 - 3.3e-07 30.3 0.0 1.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAG25373.1 - 0.027 15.1 1.4 0.06 13.9 1.4 1.6 1 0 0 1 1 1 0 HMG-box domain Fungal_trans PF04082.18 OAG25373.1 - 0.029 13.4 0.3 0.086 11.9 0.3 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain FAM60A PF15396.6 OAG25373.1 - 0.05 13.6 1.1 0.092 12.7 1.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Coiled-coil_56 PF09813.9 OAG25374.1 - 0.085 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 HET PF06985.11 OAG25375.1 - 1.3e-35 122.9 0.0 2.4e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG25376.1 - 2.8e-29 102.1 32.9 2.7e-25 89.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NADHdh_A3 PF14987.6 OAG25376.1 - 0.16 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 VIT1 PF01988.19 OAG25376.1 - 5.9 6.7 15.0 2.3 8.0 0.0 3.1 3 1 1 4 4 4 0 VIT family Wzy_C PF04932.15 OAG25376.1 - 6.3 6.4 8.8 20 4.8 8.8 2.1 1 1 0 1 1 1 0 O-Antigen ligase NAD_binding_2 PF03446.15 OAG25377.1 - 1.3e-32 113.1 0.5 2.1e-32 112.5 0.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG25377.1 - 9.1e-22 77.6 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAG25377.1 - 1.2e-06 27.7 0.0 5.8e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.12 OAG25377.1 - 8.8e-05 22.1 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OAG25377.1 - 0.00085 19.9 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.26 OAG25378.1 - 2.9e-20 72.3 0.0 5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG25378.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 UEV domain Dor1 PF04124.12 OAG25379.1 - 4.6e-52 176.8 1.8 2.5e-41 141.5 1.8 2.1 2 0 0 2 2 2 2 Dor1-like family DUF4208 PF13907.6 OAG25379.1 - 0.08 13.4 1.7 0.14 12.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) COG5 PF10392.9 OAG25379.1 - 4.3 7.5 12.2 8.1 6.6 1.9 2.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CMD PF02627.20 OAG25380.1 - 2e-14 53.4 0.0 9.2e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family A_thal_3526 PF09713.10 OAG25380.1 - 0.056 13.7 0.8 1.9 8.8 0.2 3.3 4 0 0 4 4 4 0 Plant protein 1589 of unknown function (A_thal_3526) Lactamase_B PF00753.27 OAG25381.1 - 8.7e-12 45.5 3.2 1.7e-11 44.5 3.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG25381.1 - 0.0022 17.6 0.3 0.0049 16.4 0.3 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain DAG1 PF05454.11 OAG25381.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) NAD_binding_2 PF03446.15 OAG25382.1 - 6.1e-30 104.5 0.0 8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG25382.1 - 9.5e-21 74.3 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG25382.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CMD PF02627.20 OAG25383.1 - 4.7e-21 74.6 0.1 1e-20 73.6 0.1 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.18 OAG25384.1 - 3e-14 52.7 0.3 4.2e-13 48.9 0.3 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 OAG25385.1 - 2.3e-16 59.6 0.3 6.9e-16 58.1 0.3 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG25385.1 - 1.8e-12 47.4 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TTC5_OB PF16669.5 OAG25385.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain Methyltransf_32 PF13679.6 OAG25385.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.27 OAG25386.1 - 1.6e-11 44.6 0.2 3.7e-11 43.4 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG25386.1 - 0.0019 17.8 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FHA PF00498.26 OAG25388.1 - 7e-15 55.1 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG25388.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RNA_pol_Rpb1_1 PF04997.12 OAG25389.1 - 5.8e-82 275.5 0.0 8.6e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OAG25389.1 - 1.3e-81 274.0 0.1 1.9e-81 273.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG25389.1 - 8.5e-69 231.0 0.0 1.6e-68 230.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAG25389.1 - 6e-34 117.2 0.0 1.9e-33 115.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAG25389.1 - 5.6e-27 93.8 0.0 2e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 YscO-like PF16789.5 OAG25389.1 - 0.15 12.1 0.1 0.44 10.6 0.1 1.7 1 0 0 1 1 1 0 YscO-like protein cNMP_binding PF00027.29 OAG25391.1 - 8.6e-41 137.9 0.1 8.5e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAG25391.1 - 1.5e-09 37.4 0.1 4e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AMPK1_CBM PF16561.5 OAG25392.1 - 6.3e-22 77.6 1.3 1.4e-21 76.5 1.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 OAG25392.1 - 0.00061 20.1 0.2 0.0051 17.1 0.2 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 OAG25392.1 - 0.003 18.1 1.2 0.0069 16.9 1.2 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-C2H2_2 PF12756.7 OAG25394.1 - 1.2e-24 86.5 6.2 1.4e-23 83.1 1.6 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG25394.1 - 0.00022 21.8 10.0 1.6 9.8 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger HTH_Tnp_Mu_2 PF09039.11 OAG25394.1 - 0.047 13.8 0.1 3.1 7.9 0.1 2.7 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain zf-C2H2 PF00096.26 OAG25394.1 - 0.11 13.0 0.3 0.11 13.0 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-UBP PF02148.19 OAG25394.1 - 6.6 7.1 7.9 0.31 11.4 0.2 2.6 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein ADH_N PF08240.12 OAG25396.1 - 2e-25 88.8 1.0 3.9e-25 87.9 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG25396.1 - 1.2e-12 47.9 0.1 2.5e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG25396.1 - 0.00024 20.5 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG25396.1 - 0.00025 20.4 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG25396.1 - 0.034 14.0 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRP PF06011.12 OAG25399.1 - 4.1e-162 539.8 28.9 4.9e-162 539.5 28.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG25399.1 - 1.1e-41 142.5 0.1 2.1e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 ML-like domain Pkinase PF00069.25 OAG25400.1 - 5.9e-14 52.1 0.0 1.8e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25400.1 - 7.6e-07 28.7 0.0 2.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FTHFS PF01268.19 OAG25401.1 - 3.9e-248 824.2 0.1 5.5e-248 823.7 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAG25401.1 - 1.2e-67 226.2 0.8 2.5e-67 225.2 0.8 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAG25401.1 - 3.6e-38 130.4 0.6 7.4e-38 129.4 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 OAG25401.1 - 0.0043 16.0 0.1 0.01 14.8 0.1 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family SH3_3 PF08239.11 OAG25401.1 - 0.0066 16.7 0.3 0.016 15.4 0.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_1 PF00018.28 OAG25401.1 - 0.048 13.3 0.3 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 SH3 domain DUF5401 PF17380.2 OAG25401.1 - 0.18 9.8 0.0 0.28 9.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) WD40 PF00400.32 OAG25402.1 - 1.2e-21 76.6 7.2 6.7e-06 26.7 0.1 6.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG25402.1 - 1.3e-10 41.4 0.0 0.00086 19.6 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG25402.1 - 3.6e-05 23.7 0.1 0.1 12.4 0.0 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG25402.1 - 0.0013 18.1 0.0 0.067 12.5 0.0 2.9 3 1 1 4 4 4 1 WD40-like domain MIR PF02815.19 OAG25402.1 - 0.022 14.6 0.2 0.089 12.6 0.2 1.8 1 1 1 2 2 2 0 MIR domain Nup160 PF11715.8 OAG25402.1 - 0.095 11.3 0.1 0.85 8.2 0.0 2.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 MBF1 PF08523.10 OAG25403.1 - 7.4e-26 90.4 1.8 7.4e-26 90.4 1.8 1.5 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAG25403.1 - 3.3e-07 30.3 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix His_Phos_1 PF00300.22 OAG25404.1 - 3.7e-08 33.3 0.1 1.9e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.12 OAG25405.1 - 2.1e-24 85.5 4.4 3.2e-24 84.9 4.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG25405.1 - 8.6e-13 48.4 0.0 3.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG25405.1 - 0.048 13.0 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG25405.1 - 0.069 12.4 2.1 0.16 11.2 0.0 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 OAG25407.1 - 1.5e-28 99.3 0.0 2.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG25407.1 - 3.5e-22 78.4 0.2 8.1e-22 77.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG25407.1 - 7.1e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG25407.1 - 7.9e-06 27.0 0.0 1.3e-05 26.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 OAG25407.1 - 3.3e-05 24.3 0.1 5.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 OAG25407.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.7 1 1 1 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 OAG25407.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 OAG25407.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3430 PF11912.8 OAG25409.1 - 0.0056 16.7 4.2 0.0059 16.7 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) MiAMP1 PF09117.10 OAG25409.1 - 0.0076 16.5 2.6 0.011 15.9 2.6 1.3 1 0 0 1 1 1 1 MiAMP1 GATase_6 PF13522.6 OAG25410.1 - 1e-14 54.9 0.0 2.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG25410.1 - 1.5e-11 44.3 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAG25410.1 - 9.2e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAG25410.1 - 0.03 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II 4HBT PF03061.22 OAG25411.1 - 0.00029 21.1 0.2 0.0012 19.2 0.2 1.9 1 1 0 1 1 1 1 Thioesterase superfamily Jacalin PF01419.17 OAG25412.1 - 1.8e-07 31.1 0.2 3.4e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF3455 PF11937.8 OAG25413.1 - 8e-43 146.5 0.1 1.1e-42 146.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Ank_2 PF12796.7 OAG25414.1 - 4.7e-33 113.6 5.2 3e-10 40.5 0.0 10.9 7 3 6 14 14 14 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG25414.1 - 4.6e-17 62.1 7.0 0.028 15.0 0.0 10.0 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG25414.1 - 1.8e-12 46.3 13.7 0.48 11.1 0.0 13.9 17 0 0 17 17 17 3 Ankyrin repeat Ank_5 PF13857.6 OAG25414.1 - 5.6e-12 45.6 17.1 4.2e-05 23.7 0.1 9.5 10 1 0 10 10 10 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG25414.1 - 9.1e-08 32.2 24.8 0.021 15.3 0.0 12.2 13 3 3 16 16 16 3 Ankyrin repeat Dynactin PF12455.8 OAG25415.1 - 5.4e-49 167.0 3.6 5.4e-49 167.0 3.6 3.5 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 OAG25415.1 - 2.9e-21 75.3 0.5 4.9e-21 74.5 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain IL32 PF15225.6 OAG25415.1 - 0.28 11.6 2.2 0.72 10.3 0.0 2.6 2 0 0 2 2 2 0 Interleukin 32 ABC_membrane_2 PF06472.15 OAG25416.1 - 4.4e-104 347.6 1.0 6.8e-104 347.0 1.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG25416.1 - 7.8e-19 68.5 0.0 1.4e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG25416.1 - 1.4e-05 25.1 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG25416.1 - 0.0055 17.2 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Reticulon PF02453.17 OAG25416.1 - 0.023 14.6 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Reticulon AAA_29 PF13555.6 OAG25416.1 - 0.025 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OAG25416.1 - 0.027 13.9 0.7 0.16 11.4 0.1 2.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 OAG25416.1 - 0.038 13.7 0.0 0.37 10.5 0.0 2.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG25416.1 - 0.047 14.1 0.8 0.64 10.4 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 OAG25416.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OAG25416.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 OAG25416.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OAG25416.1 - 0.21 11.3 0.1 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF726 PF05277.12 OAG25417.1 - 1.9e-127 424.9 0.4 2.7e-127 424.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pex14_N PF04695.13 OAG25417.1 - 1.6e-35 123.1 0.3 1.6e-35 123.1 0.3 4.0 5 0 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioesterase PF00975.20 OAG25417.1 - 0.0012 19.0 0.2 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain DUF900 PF05990.12 OAG25417.1 - 0.043 13.3 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 OAG25417.1 - 0.083 12.8 0.0 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Cutinase Eno-Rase_FAD_bd PF07055.12 OAG25417.1 - 0.36 11.3 2.1 1.1 9.7 2.1 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain ICL PF00463.21 OAG25418.1 - 3.7e-199 662.6 0.2 4.3e-199 662.4 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG25418.1 - 2.9e-10 40.0 0.0 2.7e-09 36.8 0.0 2.2 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase LMP PF04778.12 OAG25418.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 LMP repeated region Citrate_synt PF00285.21 OAG25419.1 - 3.7e-98 328.9 0.0 4.5e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Bact_lectin PF18483.1 OAG25419.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial lectin Glyco_hydro_3_C PF01915.22 OAG25420.1 - 1.2e-47 162.5 0.0 2.4e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG25420.1 - 9.4e-40 136.9 0.0 1.5e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG25420.1 - 8.2e-21 73.9 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Methyltransf_23 PF13489.6 OAG25421.1 - 7.9e-14 51.8 0.1 1.5e-13 51.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG25421.1 - 2.2e-10 41.1 0.0 5e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG25421.1 - 9.3e-10 39.1 0.0 2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG25421.1 - 1.9e-09 38.2 0.0 5.6e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG25421.1 - 7.8e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG25421.1 - 1.2e-06 28.3 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Zip PF02535.22 OAG25421.1 - 8.5 5.5 8.3 12 5.0 8.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TYW3 PF02676.14 OAG25422.1 - 5e-74 248.3 0.0 6.2e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PB1 PF00564.24 OAG25422.1 - 0.11 12.4 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 PB1 domain DUF2461 PF09365.10 OAG25423.1 - 1.8e-75 253.5 0.0 2.4e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Zn_clus PF00172.18 OAG25426.1 - 3.9e-08 33.3 6.4 5.6e-08 32.8 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG25429.1 - 9.7e-12 44.7 0.0 3.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25429.1 - 1.5e-11 44.4 0.0 2e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25429.1 - 0.00024 21.0 0.0 0.00064 19.7 0.0 1.6 2 0 0 2 2 2 1 KR domain ODAM PF15424.6 OAG25429.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family ALMT PF11744.8 OAG25430.1 - 2.2 7.0 6.3 2.4 6.9 6.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 OAG25430.1 - 2.6 7.3 11.8 3.3 7.0 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) polyprenyl_synt PF00348.17 OAG25431.1 - 9e-49 165.8 0.2 2e-48 164.7 0.0 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 OAG25431.1 - 0.00063 19.2 1.2 0.0018 17.7 0.4 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain PhoLip_ATPase_C PF16212.5 OAG25433.1 - 4.9e-78 262.3 26.7 4.9e-78 262.3 26.7 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG25433.1 - 3e-19 68.4 1.2 3e-19 68.4 1.2 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAG25433.1 - 9.3e-11 41.7 0.0 4.1e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG25433.1 - 2.6e-10 41.0 0.1 8e-05 23.0 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAG25433.1 - 0.00042 19.9 0.0 0.00042 19.9 0.0 2.9 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG25433.1 - 0.019 14.7 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M3 PF01432.20 OAG25434.1 - 0.098 11.9 0.6 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M3 Tetraspanin PF00335.20 OAG25435.1 - 0.00011 22.0 9.8 0.00017 21.4 9.8 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 OAG25435.1 - 2.7 7.3 4.0 0.79 9.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SRF-TF PF00319.18 OAG25436.1 - 3.6e-21 74.4 0.1 5.1e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AA_permease_2 PF13520.6 OAG25437.1 - 6.4e-53 180.1 46.4 6.4e-53 180.1 46.4 1.3 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OAG25437.1 - 2.9e-22 78.9 39.3 5.6e-22 78.0 39.3 1.4 1 1 0 1 1 1 1 Amino acid permease ATP_synth_reg PF14960.6 OAG25437.1 - 0.13 11.8 0.1 0.37 10.3 0.1 1.8 1 0 0 1 1 1 0 ATP synthase regulation SEN1_N PF12726.7 OAG25438.1 - 1.7e-200 668.0 2.9 2.3e-200 667.6 2.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAG25438.1 - 6.3e-72 242.5 1.8 6.3e-72 242.5 1.8 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 OAG25438.1 - 4.8e-61 205.9 0.0 1.1e-60 204.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG25438.1 - 2.9e-11 43.5 0.5 1.6e-06 28.0 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 OAG25438.1 - 3.2e-08 34.0 0.0 1.4e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAG25438.1 - 4.1e-06 26.7 0.0 0.058 13.1 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 OAG25438.1 - 0.00067 19.5 0.3 0.0024 17.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 OAG25438.1 - 0.0034 16.5 0.0 0.0072 15.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 OAG25438.1 - 0.0084 16.1 0.1 0.034 14.2 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.19 OAG25438.1 - 0.024 14.1 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF2075 PF09848.9 OAG25438.1 - 0.03 13.6 2.1 0.047 12.9 0.0 2.4 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2075) Annexin PF00191.20 OAG25438.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Annexin AAA_16 PF13191.6 OAG25438.1 - 0.41 11.0 5.4 0.22 11.9 0.1 3.0 2 2 0 2 2 2 0 AAA ATPase domain Acetyltransf_1 PF00583.25 OAG25440.1 - 1.5e-10 41.3 0.1 2e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG25440.1 - 8.7e-09 35.4 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG25440.1 - 1.6e-07 31.6 0.2 2.3e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rubredoxin_C PF18267.1 OAG25440.1 - 0.047 13.6 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain AdoMet_MTase PF07757.13 OAG25441.1 - 1.3e-36 125.3 0.0 8.1e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 OAG25441.1 - 0.11 12.5 0.1 0.67 9.9 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain S10_plectin PF03501.15 OAG25442.1 - 1.9e-41 140.0 0.1 2.3e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 OAG25443.1 - 3.5e-60 202.5 0.2 3.5e-60 202.5 0.2 1.5 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain RdRP_5 PF07925.11 OAG25443.1 - 0.03 11.7 0.2 0.038 11.4 0.2 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 VIT1 PF01988.19 OAG25443.1 - 2.5 7.9 5.0 3.6 7.4 5.0 1.3 1 0 0 1 1 1 0 VIT family Peptidase_M20 PF01546.28 OAG25444.1 - 4.7e-28 98.3 0.0 7.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG25444.1 - 5.2e-05 23.1 0.0 9.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG25444.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF4051 PF13260.6 OAG25446.1 - 0.031 14.0 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Rhabdo_glycop PF00974.18 OAG25446.1 - 0.052 12.0 2.5 0.85 8.0 0.3 2.1 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.6 OAG25446.1 - 0.064 14.1 0.0 0.1 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OAG25446.1 - 0.52 10.1 6.2 0.062 13.1 1.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Patatin PF01734.22 OAG25447.1 - 3.5e-14 53.5 0.0 6.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF782 PF05614.11 OAG25447.1 - 0.031 14.7 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) FAD_binding_4 PF01565.23 OAG25449.1 - 2.3e-23 82.4 2.0 4.6e-23 81.5 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 OAG25450.1 - 2.4e-17 63.2 0.0 3.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25450.1 - 0.00038 19.8 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG25450.1 - 0.0032 16.5 0.3 0.28 10.1 0.2 2.2 1 1 1 2 2 2 2 Poxvirus serine/threonine protein kinase EutQ PF06249.12 OAG25451.1 - 5.3e-11 42.5 0.0 6.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 OAG25451.1 - 5.6e-08 32.4 0.2 8.6e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAG25451.1 - 0.00079 19.1 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain SH3BGR PF04908.15 OAG25451.1 - 0.013 15.7 0.0 4.4 7.5 0.0 2.1 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Cupin_6 PF12852.7 OAG25451.1 - 0.053 13.2 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin ARD PF03079.14 OAG25451.1 - 0.12 12.6 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 ARD/ARD' family Mg_trans_NIPA PF05653.14 OAG25452.1 - 8.7e-19 67.7 7.3 1.3e-18 67.2 7.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG25452.1 - 4.2e-06 27.0 14.6 9.4e-05 22.6 0.0 3.2 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 OAG25452.1 - 0.003 16.8 4.8 0.003 16.8 4.8 2.2 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport SURF4 PF02077.15 OAG25452.1 - 0.016 14.8 0.3 0.016 14.8 0.3 1.5 2 0 0 2 2 2 0 SURF4 family TMEM61 PF15105.6 OAG25452.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family Multi_Drug_Res PF00893.19 OAG25452.1 - 0.23 12.1 8.0 2.5 8.8 0.9 3.3 3 0 0 3 3 3 0 Small Multidrug Resistance protein FXR_C1 PF16096.5 OAG25452.1 - 0.26 11.5 6.2 2.3 8.5 0.4 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF4131 PF13567.6 OAG25452.1 - 2.4 7.8 18.2 2 8.0 0.9 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4131) Neurensin PF14927.6 OAG25452.1 - 3.2 7.5 6.7 15 5.3 0.0 3.8 3 1 0 3 3 3 0 Neurensin vATP-synt_E PF01991.18 OAG25453.1 - 1.3e-67 227.1 13.1 1.5e-67 226.9 13.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SKG6 PF08693.10 OAG25454.1 - 3.8e-07 29.4 0.1 7.8e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.8 OAG25454.1 - 0.00061 20.4 3.6 0.00083 20.0 0.1 2.4 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Alpha_GJ PF03229.13 OAG25454.1 - 0.0083 16.7 5.9 0.0083 16.7 5.9 3.0 2 1 1 3 3 3 1 Alphavirus glycoprotein J DUF4448 PF14610.6 OAG25454.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Mid2 PF04478.12 OAG25454.1 - 0.053 13.4 0.3 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1996 PF09362.10 OAG25455.1 - 8.9e-62 209.1 0.4 1.4e-61 208.5 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_PH PF01138.21 OAG25456.1 - 1.3e-18 67.8 0.0 1.9e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pyr_redox_2 PF07992.14 OAG25457.1 - 1.3e-30 106.7 0.0 1.7e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG25457.1 - 3.2e-08 34.0 0.4 4.2e-06 27.2 0.7 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG25457.1 - 1.2e-05 24.8 0.6 5.5e-05 22.6 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG25457.1 - 0.00071 19.6 0.1 3.6 7.5 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG25457.1 - 0.0063 15.9 0.0 0.0063 15.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG25457.1 - 0.0064 15.4 0.0 0.0064 15.4 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.6 OAG25457.1 - 0.0079 15.4 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAG25457.1 - 0.032 13.5 0.3 0.28 10.4 0.1 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAC PF01849.18 OAG25458.1 - 1.1e-23 82.9 0.1 2.2e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 NAC domain CENP-B_dimeris PF09026.10 OAG25458.1 - 0.47 10.9 4.6 3.3 8.1 5.7 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ctr PF04145.15 OAG25459.1 - 1.2e-32 113.5 1.1 1.6e-32 113.2 1.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UCR_UQCRX_QCR9 PF05365.12 OAG25459.1 - 0.055 13.4 0.5 0.14 12.1 0.5 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like CbiK PF06180.11 OAG25459.1 - 0.094 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF456 PF04306.13 OAG25459.1 - 0.14 12.4 8.3 0.076 13.3 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Ferric_reduct PF01794.19 OAG25460.1 - 3e-21 75.8 8.7 5.7e-21 74.9 8.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG25460.1 - 2.5e-19 69.4 0.0 6.7e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG25460.1 - 2.3e-15 57.0 0.0 6.3e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAG25460.1 - 0.19 12.1 0.0 0.56 10.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pkinase PF00069.25 OAG25461.1 - 3.8e-56 190.4 0.1 6.2e-34 117.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25461.1 - 6.1e-34 117.5 0.0 4.6e-33 114.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG25461.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OAG25461.1 - 0.045 12.5 0.6 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG25461.1 - 0.18 11.7 1.7 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.6 OAG25461.1 - 0.31 11.2 3.3 0.23 11.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Macoilin PF09726.9 OAG25461.1 - 0.6 8.6 4.9 1.2 7.6 4.9 1.4 1 0 0 1 1 1 0 Macoilin family BTB PF00651.31 OAG25462.1 - 2.4e-25 88.9 0.1 1.3e-12 47.9 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 OAG25462.1 - 5.3e-08 33.2 0.0 1.5e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG25462.1 - 1.1e-07 32.0 0.0 3.5e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG25462.1 - 1.2e-07 32.2 0.1 3.2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG25462.1 - 2e-07 31.2 0.0 0.0028 18.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OAG25462.1 - 1.1e-05 25.4 0.3 0.019 15.5 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat DUF3342 PF11822.8 OAG25462.1 - 0.023 14.9 0.0 0.098 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) DLH PF01738.18 OAG25464.1 - 6.4e-19 68.4 0.0 7.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG25464.1 - 0.0034 17.1 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding PF00501.28 OAG25465.1 - 4e-67 226.6 0.0 5.4e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG25465.1 - 2.6e-05 25.1 0.0 7.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mus7 PF09462.10 OAG25466.1 - 1.8e-125 420.2 2.8 2.6e-125 419.7 2.8 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PPTA PF01239.22 OAG25467.1 - 7.8e-43 143.0 24.7 6.3e-09 35.3 0.1 6.4 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 OAG25467.1 - 0.024 14.4 0.6 3.5 7.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Rx_N PF18052.1 OAG25467.1 - 0.03 14.6 0.7 10 6.4 0.0 3.2 2 1 0 2 2 2 0 Rx N-terminal domain ANAPC4_WD40 PF12894.7 OAG25468.1 - 2.7e-09 37.2 0.0 0.053 13.8 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG25468.1 - 1.2e-05 26.0 6.1 0.0054 17.5 0.0 4.9 7 0 0 7 7 7 2 WD domain, G-beta repeat PrpF PF04303.13 OAG25469.1 - 2.7e-78 263.5 0.5 1.4e-73 248.0 0.1 2.0 2 0 0 2 2 2 2 PrpF protein GrpE PF01025.19 OAG25470.1 - 3.9e-47 160.0 4.5 4.8e-47 159.7 4.5 1.1 1 0 0 1 1 1 1 GrpE DUF4201 PF13870.6 OAG25470.1 - 0.0032 17.2 0.7 0.0052 16.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF641 PF04859.12 OAG25470.1 - 0.0049 17.2 0.3 0.021 15.2 0.4 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 OAG25470.1 - 0.027 14.5 6.3 0.062 13.3 6.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 OAG25470.1 - 1.4 9.2 8.4 1.7 8.9 6.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNA_pol_A_bac PF01000.26 OAG25471.1 - 9.5e-31 106.5 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG25471.1 - 8e-16 57.2 0.0 1e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.12 OAG25472.1 - 1.5e-42 145.5 0.2 2.1e-42 145.0 0.2 1.2 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 OAG25472.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S6e PF01092.19 OAG25473.1 - 8.1e-59 197.1 0.1 1e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e p450 PF00067.22 OAG25474.1 - 4.4e-65 220.2 0.0 5.5e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 OAG25475.1 - 1.1e-56 188.7 2.5 1.1e-20 73.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4458 PF14660.6 OAG25475.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) tRNA-synt_2d PF01409.20 OAG25476.1 - 6.1e-46 156.9 0.3 6.7e-26 91.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAG25476.1 - 4.5e-24 84.7 0.0 2.4e-23 82.4 0.0 2.2 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Uds1 PF15456.6 OAG25477.1 - 9.1e-29 100.3 6.5 9.1e-29 100.3 6.5 1.7 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 OAG25477.1 - 0.042 13.8 0.4 0.042 13.8 0.4 2.1 2 0 0 2 2 2 0 Stathmin family APG6_N PF17675.1 OAG25477.1 - 0.15 12.6 2.4 0.29 11.7 2.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Pribosyltran_N PF13793.6 OAG25478.1 - 6.4e-45 151.8 0.0 8.3e-44 148.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG25478.1 - 6.5e-44 150.2 0.5 5.7e-37 127.5 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG25478.1 - 3.4e-16 59.2 1.2 5.8e-15 55.2 0.7 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG25478.1 - 0.0012 18.4 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Lipase_GDSL_2 PF13472.6 OAG25479.1 - 6.9e-21 75.4 1.8 9.3e-21 75.0 1.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 OAG25479.1 - 3.2e-19 69.0 0.1 5.3e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 OAG25479.1 - 1.2e-10 41.7 0.1 1.9e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OAG25479.1 - 0.004 17.3 0.0 0.0073 16.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1751 PF08551.10 OAG25480.1 - 7.9e-26 90.5 3.6 7.9e-26 90.5 3.6 1.6 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) LisH PF08513.11 OAG25481.1 - 0.00015 21.6 0.1 0.00027 20.8 0.1 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.32 OAG25481.1 - 0.00081 20.2 5.2 6.9 7.7 0.2 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 OAG25481.1 - 0.0037 17.2 0.2 0.22 11.4 0.1 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A NAD_binding_8 PF13450.6 OAG25482.1 - 4e-09 36.6 0.0 1.3e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG25482.1 - 2.4e-08 33.5 0.0 1.1e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OAG25482.1 - 3.3e-06 25.8 0.2 0.00026 19.6 0.2 3.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG25482.1 - 3.6e-05 23.1 0.0 0.018 14.3 0.0 2.6 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG25482.1 - 6.3e-05 23.0 0.2 0.048 13.7 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG25482.1 - 0.00047 19.8 0.0 0.53 9.8 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG25482.1 - 0.0005 19.4 0.0 0.54 9.4 0.0 3.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG25482.1 - 0.017 13.8 0.2 0.06 12.0 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAG25482.1 - 0.018 14.3 0.0 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Amnionless PF14828.6 OAG25483.1 - 0.032 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless ABC2_membrane_3 PF12698.7 OAG25483.1 - 0.069 12.2 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TrbL PF04610.14 OAG25483.1 - 0.12 12.1 1.3 0.28 10.9 1.3 1.6 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MAP17 PF15807.5 OAG25483.1 - 0.14 12.4 0.3 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 OAG25483.1 - 0.16 12.8 0.3 0.56 11.1 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 OAG25483.1 - 0.19 11.7 1.3 0.33 10.9 1.3 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LapA_dom PF06305.11 OAG25484.1 - 0.025 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FeoB_associated PF12669.7 OAG25484.1 - 0.23 11.9 0.1 0.4 11.1 0.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Peptidase_M20 PF01546.28 OAG25485.1 - 0.22 11.2 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 AMP-binding PF00501.28 OAG25486.1 - 3.2e-85 286.3 0.0 4.3e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG25486.1 - 2.6e-27 95.6 0.4 7.6e-26 90.9 0.5 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG25486.1 - 8.5e-20 70.4 0.1 2.3e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 OAG25487.1 - 2.2e-62 210.7 8.2 2.2e-62 210.7 8.2 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAG25487.1 - 6.1e-47 160.0 5.3 1.6e-46 158.7 5.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG25487.1 - 5.4e-44 150.3 4.5 9.6e-44 149.5 4.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAG25487.1 - 5e-16 59.3 31.8 5e-16 59.3 31.8 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAG25487.1 - 4.1e-11 43.5 1.4 8.5e-11 42.5 0.3 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 OAG25487.1 - 0.00046 20.6 10.2 0.00046 20.6 10.2 4.9 2 1 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 OAG25487.1 - 0.0094 16.2 0.1 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide LapA_dom PF06305.11 OAG25487.1 - 0.036 13.9 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 OAG25488.1 - 1.3e-64 218.6 0.0 1.7e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Psu PF07455.11 OAG25488.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) NmrA PF05368.13 OAG25489.1 - 1.9e-12 47.2 0.0 2.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG25489.1 - 7.1e-07 29.3 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Ntox22 PF15527.6 OAG25489.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 2 1 0 2 2 2 0 Bacterial toxin 22 3Beta_HSD PF01073.19 OAG25489.1 - 0.14 11.2 0.0 0.26 10.2 0.0 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA PF00004.29 OAG25490.1 - 2.2e-39 134.9 0.0 7.4e-38 130.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG25490.1 - 3.4e-09 36.4 0.6 1.1e-08 34.8 0.6 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OAG25490.1 - 1.7e-05 24.6 0.0 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAG25490.1 - 0.00014 22.1 0.5 0.018 15.2 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG25490.1 - 0.0015 18.8 0.4 0.082 13.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OAG25490.1 - 0.0032 17.4 0.0 0.01 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG25490.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAG25490.1 - 0.013 15.6 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OAG25490.1 - 0.014 14.6 0.6 0.023 13.9 0.2 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 OAG25490.1 - 0.014 15.9 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG25490.1 - 0.016 15.0 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 OAG25490.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG25490.1 - 0.053 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OAG25490.1 - 0.058 13.8 8.5 0.03 14.7 1.3 4.0 3 2 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 OAG25490.1 - 0.076 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OAG25490.1 - 0.078 13.4 0.6 0.3 11.5 0.3 2.2 1 1 1 2 2 2 0 AAA domain MFS_1 PF07690.16 OAG25491.1 - 3e-15 56.0 45.2 3e-15 56.0 45.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG25491.1 - 3.5e-06 26.1 13.4 5.2e-06 25.6 12.6 1.6 1 1 0 1 1 1 1 MFS_1 like family WD40 PF00400.32 OAG25492.1 - 2.9e-22 78.5 21.8 7.1e-06 26.7 0.2 9.7 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG25492.1 - 3.6e-10 40.0 0.1 1.1 9.7 0.0 6.0 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 OAG25492.1 - 0.019 14.0 0.1 0.97 8.4 0.0 2.5 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 OAG25492.1 - 0.091 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 OAG25492.1 - 0.1 12.6 1.8 7.5 6.6 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 OAG25493.1 - 1e-06 28.2 0.0 0.0023 17.2 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG25493.1 - 0.00057 19.4 0.0 0.73 9.3 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG25493.1 - 0.02 15.5 0.1 0.043 14.4 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG25493.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_7 PF12715.7 OAG25493.1 - 0.08 12.2 0.0 3.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase family DUF915 PF06028.11 OAG25493.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) p450 PF00067.22 OAG25494.1 - 6.5e-71 239.5 0.0 8.2e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG25495.1 - 1.2e-22 80.3 0.1 1.8e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain YjcB PF15940.5 OAG25496.1 - 0.61 10.3 5.7 14 5.9 0.1 3.0 2 2 0 2 2 2 0 Family of unknown function Mucin PF01456.17 OAG25496.1 - 3.6 7.6 25.3 0.18 11.8 19.5 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 OAG25496.1 - 9.7 4.0 9.5 12 3.7 9.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V-SNARE PF05008.15 OAG25497.1 - 1.5e-20 73.3 3.8 1.5e-20 73.3 3.8 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OAG25497.1 - 8.3e-18 64.4 7.2 8.3e-18 64.4 7.2 2.3 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAG25497.1 - 0.0045 16.9 1.4 0.0073 16.2 0.2 2.0 2 0 0 2 2 2 1 Sec20 Fusion_gly PF00523.18 OAG25497.1 - 0.017 13.4 0.7 0.027 12.7 0.1 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0 Spectrin PF00435.21 OAG25497.1 - 0.056 13.9 5.6 0.072 13.6 0.3 2.8 1 1 2 3 3 3 0 Spectrin repeat Synaptobrevin PF00957.21 OAG25497.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.4 3 0 0 3 3 3 0 Synaptobrevin YqjK PF13997.6 OAG25497.1 - 0.21 11.9 0.1 0.21 11.9 0.1 2.4 3 0 0 3 3 3 0 YqjK-like protein Prominin PF05478.11 OAG25497.1 - 3.1 5.6 6.0 1.9 6.3 0.6 2.0 1 1 0 2 2 2 0 Prominin Exonuc_VII_L PF02601.15 OAG25497.1 - 3.4 7.1 12.5 24 4.4 12.5 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit NAD_binding_8 PF13450.6 OAG25498.1 - 5.8e-14 52.1 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG25498.1 - 2.3e-11 43.6 0.8 1.8e-10 40.8 0.8 2.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAG25498.1 - 1.2e-05 24.7 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG25498.1 - 1.6e-05 24.6 0.1 6.8e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG25498.1 - 0.00063 19.8 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG25498.1 - 0.00081 18.6 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG25498.1 - 0.0016 18.9 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG25498.1 - 0.0018 16.7 0.0 0.0032 15.9 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 OAG25498.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Prenylcys_lyase PF07156.14 OAG25498.1 - 0.097 11.8 0.0 0.83 8.7 0.0 2.0 1 1 0 1 1 1 0 Prenylcysteine lyase MCRA PF06100.11 OAG25498.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family DUF2470 PF10615.9 OAG25499.1 - 0.023 15.3 0.1 0.098 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) TMEM252 PF15664.5 OAG25499.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF1996 PF09362.10 OAG25500.1 - 1.5e-81 273.9 2.0 1.8e-81 273.6 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RGS PF00615.19 OAG25503.1 - 8.7e-07 29.2 0.0 0.00031 21.0 0.0 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain Pox_A14 PF05767.12 OAG25503.1 - 0.29 11.3 0.1 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SnoaL_4 PF13577.6 OAG25504.1 - 6.5e-14 52.2 0.0 7.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 OAG25506.1 - 6.8e-52 176.4 0.1 7.9e-52 176.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG25506.1 - 1.3e-49 168.3 0.1 1.6e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG25506.1 - 1.6e-09 37.9 0.1 3.7e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 OAG25506.1 - 0.00042 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG25506.1 - 0.025 14.0 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG25506.1 - 0.1 12.0 0.0 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) E_raikovi_mat PF06360.11 OAG25507.1 - 0.079 13.4 5.8 0.27 11.7 1.7 2.3 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone zf-PARP PF00645.18 OAG25508.1 - 1.3e-23 83.7 0.2 1.1e-15 58.2 0.1 2.8 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ldh_2 PF02615.14 OAG25509.1 - 1.5e-124 415.5 0.7 1.7e-124 415.4 0.7 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase GFO_IDH_MocA PF01408.22 OAG25510.1 - 1.5e-13 51.6 0.0 2.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG25510.1 - 0.00027 21.6 0.1 0.00071 20.2 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Glyco_transf_34 PF05637.12 OAG25511.1 - 4.8e-10 39.6 0.3 1.3e-09 38.2 0.3 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 OAG25511.1 - 2.3e-05 24.5 0.2 4.6e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 OAG25511.1 - 0.0038 16.8 0.1 0.0069 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Aldedh PF00171.22 OAG25512.1 - 1.3e-77 261.3 0.0 1.5e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_4C PF11975.8 OAG25513.1 - 0.043 13.9 0.3 0.058 13.5 0.3 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Fungal_trans PF04082.18 OAG25514.1 - 5.7e-13 48.5 2.2 5.7e-13 48.5 2.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG25514.1 - 1.8e-07 31.2 12.1 0.00055 20.3 4.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25514.1 - 0.00044 20.9 9.2 0.039 14.8 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG25514.1 - 0.0082 16.5 2.7 0.16 12.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-RING_2 PF13639.6 OAG25516.1 - 7.4e-09 35.8 3.9 1.8e-08 34.6 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG25516.1 - 6.3e-06 25.8 1.9 1.9e-05 24.3 1.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG25516.1 - 1.4e-05 25.3 2.6 2.9e-05 24.3 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG25516.1 - 3.9e-05 23.4 4.2 0.0001 22.1 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG25516.1 - 0.0001 22.3 1.0 0.00028 20.9 1.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAG25516.1 - 0.00011 22.1 6.5 0.00033 20.6 6.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAG25516.1 - 0.00013 22.1 1.6 0.00039 20.5 1.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAG25516.1 - 0.00063 19.7 4.6 0.0013 18.6 3.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG25516.1 - 0.0014 18.5 5.7 0.0028 17.5 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG25516.1 - 0.0028 17.5 3.4 0.011 15.6 3.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG25516.1 - 0.016 15.0 1.3 0.068 13.0 1.6 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf_Rg PF17915.1 OAG25516.1 - 0.025 14.0 1.0 0.071 12.5 1.0 1.7 1 0 0 1 1 1 0 Reverse gyrase zinc finger FANCL_C PF11793.8 OAG25516.1 - 0.039 14.1 6.0 0.16 12.1 6.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-TFIIIC PF12660.7 OAG25516.1 - 0.056 13.4 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DUF3263 PF11662.8 OAG25516.1 - 0.081 12.8 0.0 0.37 10.7 0.0 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3263) PHD PF00628.29 OAG25516.1 - 0.19 11.7 2.9 0.41 10.6 2.9 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 OAG25516.1 - 0.67 9.9 6.0 2.6 8.0 6.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Peroxidase_2 PF01328.17 OAG25517.1 - 1.7e-46 159.1 0.0 2.4e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.22 OAG25518.1 - 3.3e-35 121.8 0.0 9.2e-25 87.3 0.3 2.4 1 1 1 2 2 2 2 Cytochrome P450 HATPase_c PF02518.26 OAG25519.1 - 5.9e-24 84.7 0.0 1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG25519.1 - 3.4e-17 62.6 0.2 7.2e-12 45.5 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 OAG25519.1 - 5.9e-09 35.8 0.0 1.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAG25519.1 - 9e-07 29.1 0.0 0.097 12.9 0.0 4.2 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 OAG25519.1 - 0.00046 20.1 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 OAG25519.1 - 0.0081 16.4 0.1 0.086 13.1 0.1 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG25519.1 - 0.047 14.0 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 PAS domain GAF_2 PF13185.6 OAG25519.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 GAF domain adh_short PF00106.25 OAG25520.1 - 3e-38 131.3 0.2 5.5e-38 130.4 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25520.1 - 7.7e-38 130.3 0.3 2e-36 125.7 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25520.1 - 1.5e-10 41.3 1.9 6.6e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 OAG25520.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HATPase_c PF02518.26 OAG25520.1 - 0.013 16.0 0.1 0.029 14.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox PF00070.27 OAG25520.1 - 0.048 14.2 0.4 0.17 12.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAG25520.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Epimerase PF01370.21 OAG25520.1 - 0.11 11.9 0.2 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG25520.1 - 0.13 11.7 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Peptidase_M24 PF00557.24 OAG25522.1 - 4.6e-34 117.9 0.9 5.9e-34 117.6 0.9 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4854 PF16146.5 OAG25522.1 - 0.012 15.9 0.0 20 5.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4854) CDT1_C PF16679.5 OAG25522.1 - 0.33 11.4 0.0 0.33 11.4 0.0 2.2 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain C2 PF00168.30 OAG25524.1 - 9.9e-16 57.9 0.0 1.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Tyrosinase PF00264.20 OAG25529.1 - 4.9e-52 177.4 0.1 6.3e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.28 OAG25530.1 - 3.5e-85 286.8 0.4 4.6e-85 286.4 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG25530.1 - 8.3e-07 29.1 0.1 6.8e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG25530.1 - 0.037 12.9 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 OAG25530.1 - 0.055 12.4 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2244 PF10003.9 OAG25531.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) SUA5 PF03481.13 OAG25531.1 - 1.2 9.7 6.2 12 6.4 1.7 2.5 2 1 0 2 2 2 0 Putative GTP-binding controlling metal-binding DUF3328 PF11807.8 OAG25532.1 - 5.7e-22 78.6 12.0 1.6e-20 73.9 12.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SelK_SelG PF10961.8 OAG25533.1 - 0.69 10.6 3.4 15 6.2 0.2 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG TMEM43 PF07787.12 OAG25533.1 - 1.3 8.3 4.7 0.73 9.2 0.9 1.8 1 1 1 2 2 2 0 Transmembrane protein 43 Glyco_hydro_16 PF00722.21 OAG25534.1 - 1e-10 41.4 0.0 2.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 F-box-like_2 PF13013.6 OAG25535.1 - 0.0016 18.4 0.1 0.0038 17.2 0.1 1.6 2 0 0 2 2 2 1 F-box-like domain F-box-like_2 PF13013.6 OAG25536.1 - 0.0067 16.4 1.7 0.011 15.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like domain F-box-like_2 PF13013.6 OAG25537.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain HTHP PF11534.8 OAG25537.1 - 0.18 12.2 0.8 0.8 10.2 0.0 2.1 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) Acetyltransf_1 PF00583.25 OAG25539.1 - 0.039 14.2 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NKAIN PF05640.14 OAG25540.1 - 0.0036 16.6 0.1 0.0036 16.6 0.1 2.1 2 0 0 2 2 2 1 Na,K-Atpase Interacting protein DUF4083 PF13314.6 OAG25540.1 - 0.15 12.0 0.7 0.49 10.4 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) CLLAC PF15675.5 OAG25540.1 - 1.8 8.2 7.0 0.43 10.2 0.9 2.7 2 0 0 2 2 2 0 CLLAC-motif containing domain Beta-lactamase PF00144.24 OAG25541.1 - 4.3e-39 134.7 0.1 6.9e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 OAG25542.1 - 1.3e-40 139.4 45.2 1.3e-40 139.4 45.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25542.1 - 6.2e-14 51.7 10.4 6.2e-14 51.7 10.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short_C2 PF13561.6 OAG25543.1 - 3.5e-55 187.1 0.5 4e-55 186.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG25543.1 - 1.6e-37 128.9 1.2 2e-37 128.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG25543.1 - 3.4e-12 46.6 0.3 4.5e-12 46.2 0.3 1.1 1 0 0 1 1 1 1 KR domain EcoEI_R_C PF08463.10 OAG25544.1 - 0.019 15.1 0.3 0.12 12.4 0.1 2.1 2 1 0 2 2 2 0 EcoEI R protein C-terminal DUF812 PF05667.11 OAG25546.1 - 0.0091 14.9 10.3 0.013 14.4 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Nup54 PF13874.6 OAG25546.1 - 0.39 10.8 9.6 0.15 12.2 6.4 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Prominin PF05478.11 OAG25546.1 - 9.7 4.0 13.8 14 3.5 13.8 1.1 1 0 0 1 1 1 0 Prominin CrgA PF06781.12 OAG25547.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Cell division protein CrgA MGC-24 PF05283.11 OAG25547.1 - 1.1 9.7 5.7 0.36 11.3 2.6 1.6 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_61 PF03443.14 OAG25548.1 - 4.4e-64 216.2 0.0 5e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_10 PF13460.6 OAG25549.1 - 3.4e-16 59.7 0.0 1.4e-15 57.7 0.0 2.0 1 1 2 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 OAG25549.1 - 1.3e-15 57.6 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 OAG25549.1 - 0.00054 20.4 0.1 0.0014 19.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG25549.1 - 0.0032 17.6 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 OAG25549.1 - 0.014 14.7 0.1 0.077 12.3 0.1 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG25549.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 OAG25550.1 - 5.9e-47 160.3 47.7 5.9e-47 160.3 47.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG25550.1 - 4e-12 45.3 18.8 6.3e-12 44.7 18.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG25550.1 - 8.2e-10 38.1 11.9 8.2e-10 38.1 11.9 2.7 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAG25550.1 - 0.0021 16.4 23.7 0.037 12.3 1.8 3.5 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OAG25551.1 - 3.1e-37 128.3 33.9 3.1e-37 128.3 33.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25551.1 - 8.7e-11 41.3 5.1 8.7e-11 41.3 5.1 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4118 PF13493.6 OAG25551.1 - 0.011 15.5 3.5 0.011 15.5 3.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) F-box-like_2 PF13013.6 OAG25553.1 - 0.0032 17.4 0.2 0.0089 16.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like domain Aldo_ket_red PF00248.21 OAG25556.1 - 4.7e-54 183.6 0.0 5.7e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.15 OAG25556.1 - 0.15 12.2 0.0 3.2 7.9 0.0 2.6 3 0 0 3 3 3 0 Raf-like Ras-binding domain Aa_trans PF01490.18 OAG25557.1 - 6e-33 114.1 34.9 7.4e-33 113.8 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 OAG25557.1 - 0.0009 17.9 27.2 0.0009 17.9 27.2 2.2 2 0 0 2 2 2 1 Amino acid permease DUF2275 PF10039.9 OAG25557.1 - 0.097 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF4806 PF16064.5 OAG25557.1 - 0.099 13.0 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DUF3679 PF12438.8 OAG25557.1 - 1.8 8.3 4.7 1.8 8.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) Cutinase PF01083.22 OAG25560.1 - 2.1e-27 96.2 0.2 2.8e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 Cutinase DUF3638 PF12340.8 OAG25561.1 - 1.2e-88 296.2 0.7 2.9e-88 295.0 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) MFS_1 PF07690.16 OAG25562.1 - 4.7e-35 121.2 28.7 1.3e-34 119.7 27.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25562.1 - 1.6e-14 53.6 3.2 1.6e-14 53.6 3.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Aldedh PF00171.22 OAG25564.1 - 1.6e-116 389.6 6.3 1.8e-116 389.4 6.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_trans_2_3 PF13632.6 OAG25565.1 - 2.9e-51 174.2 0.3 2.9e-51 174.2 0.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG25565.1 - 2.2e-07 30.9 0.0 3.3e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG25565.1 - 0.00025 21.0 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG25565.1 - 0.0032 17.0 0.7 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 ACP_syn_III PF08545.10 OAG25565.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Wzz PF02706.15 OAG25565.1 - 0.64 10.3 2.9 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Chain length determinant protein HORMA PF02301.18 OAG25566.1 - 9.8e-32 110.3 0.1 9.8e-32 110.3 0.1 1.6 2 0 0 2 2 2 1 HORMA domain DUF3530 PF12048.8 OAG25566.1 - 6.6e-05 22.5 0.9 0.037 13.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3530) ATG101 PF07855.12 OAG25566.1 - 0.0013 18.7 0.5 0.0047 16.9 0.5 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 Phasin PF05597.11 OAG25566.1 - 0.0064 16.5 0.6 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4760 PF15956.5 OAG25566.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) RAP1 PF07218.11 OAG25566.1 - 0.079 11.2 6.8 0.11 10.7 6.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.12 OAG25566.1 - 0.55 10.6 4.4 1.9 8.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) GTP_EFTU PF00009.27 OAG25567.1 - 7.7e-50 169.1 0.0 1.2e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAG25567.1 - 1.4e-42 144.1 2.1 2.4e-42 143.4 2.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAG25567.1 - 5.2e-19 68.1 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG25567.1 - 2.9e-07 30.8 0.1 7.2e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG25567.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG25567.1 - 0.00029 20.5 0.0 0.00077 19.1 0.0 1.7 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 OAG25567.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 OAG25567.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 OAG25567.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 OAG25567.1 - 0.34 11.2 3.4 0.71 10.1 3.4 1.5 1 0 0 1 1 1 0 Snurportin1 Sugar_tr PF00083.24 OAG25568.1 - 2.6e-87 293.6 34.2 3.2e-87 293.3 34.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG25568.1 - 4.7e-16 58.6 44.4 4.7e-16 58.6 44.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RhgB_N PF09284.10 OAG25569.1 - 4e-86 288.6 0.2 5.6e-86 288.2 0.2 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 OAG25569.1 - 3.2e-33 114.9 0.1 3.2e-33 114.9 0.1 2.4 4 0 0 4 4 4 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG25569.1 - 9e-15 54.2 4.1 9e-15 54.2 4.1 2.4 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG25569.1 - 0.00014 22.0 0.4 0.00041 20.6 0.4 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4278 PF14105.6 OAG25569.1 - 0.011 16.2 0.3 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4278) WW PF00397.26 OAG25570.1 - 1.1e-08 35.1 1.6 1.1e-08 35.1 1.6 2.1 2 0 0 2 2 2 1 WW domain GRP PF07172.11 OAG25570.1 - 1.6 9.5 8.0 3.2 8.5 0.8 2.1 2 0 0 2 2 2 0 Glycine rich protein family Fe_dep_repress PF01325.19 OAG25571.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain OTU PF02338.19 OAG25573.1 - 2.4e-17 63.6 3.5 3.4e-17 63.1 0.5 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAG25573.1 - 0.00017 21.1 0.0 0.054 12.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase C65 Otubain PepSY_2 PF13670.6 OAG25573.1 - 0.51 10.4 0.0 0.51 10.4 0.0 2.7 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain ALMT PF11744.8 OAG25573.1 - 5.8 5.6 12.3 21 3.8 12.4 1.6 1 1 1 2 2 2 0 Aluminium activated malate transporter GAGA_bind PF06217.12 OAG25573.1 - 9.4 6.4 10.2 16 5.6 10.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family TPMT PF05724.11 OAG25574.1 - 5.4e-25 88.3 0.0 6.1e-22 78.4 0.0 2.3 2 1 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OAG25574.1 - 5.5e-05 23.1 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG25574.1 - 0.0015 19.2 0.0 0.013 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG25574.1 - 0.0037 17.9 0.0 0.011 16.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OAG25574.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Methyltransf_12 PF08242.12 OAG25574.1 - 0.083 13.6 0.0 0.17 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 OAG25575.1 - 1.5e-44 152.4 35.2 1.5e-44 152.4 35.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25575.1 - 7.2e-11 41.6 10.2 7.2e-11 41.6 10.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 OAG25575.1 - 0.00014 20.6 9.4 0.00014 20.6 9.4 3.3 2 2 1 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 OAG25575.1 - 0.063 11.6 17.1 0.014 13.7 2.0 3.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family stn_TNFRSF12A PF12191.8 OAG25576.1 - 0.044 14.0 0.5 0.12 12.6 0.2 1.9 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MFS_1 PF07690.16 OAG25577.1 - 1.1e-45 156.1 37.3 1.1e-45 156.1 37.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG25577.1 - 0.0022 16.4 10.3 0.0077 14.6 4.7 3.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2 PF00096.26 OAG25578.1 - 6.8e-05 23.1 10.8 0.1 13.1 0.3 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OAG25578.1 - 0.002 17.9 8.3 0.49 10.2 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OAG25578.1 - 0.087 13.7 17.1 0.74 10.8 0.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG25578.1 - 9.9 6.8 25.4 0.26 11.8 0.6 4.6 5 0 0 5 5 5 0 Zinc-finger double domain Lactonase PF10282.9 OAG25579.1 - 2e-05 24.0 0.4 0.46 9.7 0.0 3.2 1 1 2 3 3 3 3 Lactonase, 7-bladed beta-propeller Glyco_hydro_10 PF00331.20 OAG25580.1 - 2.5e-77 260.1 0.6 2.8e-77 260.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Esterase_phd PF10503.9 OAG25583.1 - 2.1e-24 86.2 0.9 2.9e-24 85.8 0.9 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG25583.1 - 1.6e-09 37.6 1.0 2.8e-09 36.7 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG25583.1 - 0.001 18.9 0.6 0.0069 16.2 0.1 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 OAG25583.1 - 0.0013 18.4 0.8 0.0017 18.0 0.8 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OAG25583.1 - 0.0036 17.2 0.3 0.0072 16.2 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG25583.1 - 0.011 14.7 1.0 0.011 14.7 1.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 OAG25583.1 - 0.012 14.9 0.1 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG25583.1 - 0.037 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 OAG25583.1 - 0.043 13.4 5.4 0.06 12.9 5.4 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 OAG25583.1 - 0.12 12.3 0.5 0.21 11.5 0.5 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAG25583.1 - 0.28 10.7 3.3 3.5 7.1 3.2 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Clat_adaptor_s PF01217.20 OAG25584.1 - 1.7e-41 141.5 0.0 4.8e-41 140.0 0.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 OAG25585.1 - 1.9e-32 111.6 0.0 2.4e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.13 OAG25586.1 - 8.1e-20 70.3 2.2 1.1e-19 69.9 2.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Sec6 PF06046.13 OAG25587.1 - 6.5e-156 520.0 9.4 6.5e-156 520.0 9.4 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 FANCI_S3 PF14677.6 OAG25587.1 - 0.017 14.9 0.1 0.57 9.9 0.1 2.8 2 0 0 2 2 2 0 FANCI solenoid 3 AAA_13 PF13166.6 OAG25587.1 - 0.028 13.1 4.6 0.037 12.7 3.8 1.5 1 1 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.17 OAG25587.1 - 0.084 13.2 4.5 3.1 8.2 0.1 4.5 4 0 0 4 4 4 0 Retrotransposon gag protein Noelin-1 PF12308.8 OAG25587.1 - 0.097 12.7 1.8 2.7 8.0 0.3 2.9 2 0 0 2 2 2 0 Neurogenesis glycoprotein Cathelicidins PF00666.17 OAG25587.1 - 0.1 12.9 0.1 0.34 11.2 0.1 1.8 1 0 0 1 1 1 0 Cathelicidin Mis14 PF08641.12 OAG25587.1 - 1.4 9.2 6.5 4.7 7.5 0.3 3.7 4 1 0 4 4 4 0 Kinetochore protein Mis14 like Utp12 PF04003.12 OAG25591.1 - 8e-26 90.4 0.1 1.3e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.25 OAG25592.1 - 3.4e-39 132.8 2.9 1.6e-20 72.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OAG25592.1 - 5.6e-19 68.1 0.2 1.6e-18 66.6 0.2 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 OAG25592.1 - 9.9 6.2 14.3 0.22 11.6 6.0 2.5 2 0 0 2 2 2 0 FlxA-like protein TIP49 PF06068.13 OAG25593.1 - 3.7e-162 539.5 0.0 4.4e-162 539.2 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG25593.1 - 6.5e-20 71.0 0.1 2.1e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAG25593.1 - 1.1e-10 42.1 0.2 2.5e-07 31.2 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG25593.1 - 3.1e-09 36.8 0.6 2.7e-06 27.2 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG25593.1 - 1.9e-05 25.0 0.2 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG25593.1 - 2.8e-05 24.6 0.4 0.00055 20.4 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAG25593.1 - 6.3e-05 23.4 0.7 0.063 13.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAG25593.1 - 0.00062 19.8 0.2 0.2 11.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG25593.1 - 0.00075 19.8 0.3 0.0025 18.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAG25593.1 - 0.0034 17.1 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAG25593.1 - 0.0061 15.9 0.4 0.014 14.7 0.3 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 OAG25593.1 - 0.025 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG25593.1 - 0.026 13.9 0.3 0.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG25593.1 - 0.039 13.3 0.1 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 OAG25593.1 - 0.043 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 OAG25593.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 OAG25593.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAG25593.1 - 0.086 12.6 0.2 0.61 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG25593.1 - 0.1 12.1 0.2 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAG25593.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1674 PF07896.12 OAG25594.1 - 1.1e-17 64.2 7.1 1.1e-17 64.2 7.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) COesterase PF00135.28 OAG25596.1 - 2.9e-77 260.7 0.2 5.4e-76 256.5 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG25596.1 - 9e-07 29.0 0.1 2.1e-05 24.5 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG25596.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family zinc_ribbon_16 PF17034.5 OAG25597.1 - 0.061 13.5 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family Ceramidase_alk PF04734.13 OAG25598.1 - 1.5e-224 746.3 0.0 1.8e-224 746.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAG25598.1 - 2.2e-60 203.3 0.2 3.5e-60 202.7 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal ErmC PF06308.11 OAG25598.1 - 0.064 13.6 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) BCAS2 PF05700.11 OAG25599.1 - 2.2e-48 164.7 0.8 2.6e-48 164.4 0.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF349 PF03993.12 OAG25599.1 - 0.55 10.6 4.5 1.5 9.1 1.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RSN1_7TM PF02714.15 OAG25600.1 - 4.2e-92 308.3 22.9 9.5e-92 307.2 19.9 2.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG25600.1 - 1.2e-43 148.6 0.6 1.2e-43 148.6 0.6 2.8 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG25600.1 - 2.2e-30 106.2 0.3 3.9e-30 105.4 0.3 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG25600.1 - 5.7e-23 80.9 0.2 1.4e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Sugar_tr PF00083.24 OAG25601.1 - 2.3e-77 260.8 12.7 2.6e-77 260.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG25601.1 - 5.6e-30 104.5 11.9 8.2e-30 103.9 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG25601.1 - 0.014 13.8 0.3 0.014 13.8 0.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG25601.1 - 0.032 12.5 3.0 0.086 11.1 0.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AA_permease PF00324.21 OAG25602.1 - 3.3e-126 421.7 42.9 3.9e-126 421.5 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG25602.1 - 2.4e-36 125.5 43.9 3.2e-36 125.1 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3431 PF11913.8 OAG25603.1 - 4.2e-80 268.6 0.4 5.2e-80 268.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Peptidase_A4 PF01828.17 OAG25605.1 - 1.2e-75 253.6 12.3 1.5e-75 253.3 12.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family Glyco_hydro_61 PF03443.14 OAG25606.1 - 1.9e-55 188.0 0.1 2.5e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4225 PF13988.6 OAG25607.1 - 0.48 10.0 6.7 0.55 9.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) Asp PF00026.23 OAG25608.1 - 4e-11 42.9 0.2 5.4e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease LapA_dom PF06305.11 OAG25608.1 - 0.074 12.9 1.6 0.098 12.5 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 OAG25609.1 - 6.3e-68 229.0 0.0 7.9e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25609.1 - 3.6e-32 111.7 0.0 5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG25609.1 - 0.0067 15.4 0.0 0.021 13.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG25609.1 - 0.05 13.0 0.1 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG25609.1 - 0.051 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Epimerase PF01370.21 OAG25610.1 - 2.6e-14 53.3 0.1 3.4e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG25610.1 - 5.1e-07 29.8 0.0 9.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG25610.1 - 2.2e-05 24.1 0.2 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG25610.1 - 6.6e-05 22.1 0.0 0.0086 15.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG25610.1 - 9.9e-05 22.0 0.0 0.00021 20.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 OAG25610.1 - 0.0023 17.1 0.3 0.0083 15.3 0.3 1.9 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 OAG25610.1 - 0.026 15.0 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG25610.1 - 0.11 11.6 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG25610.1 - 0.13 12.5 0.0 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DEAD PF00270.29 OAG25611.1 - 1.1e-46 158.8 0.1 2.6e-46 157.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG25611.1 - 8.8e-25 87.2 0.0 4.6e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG25611.1 - 2.6e-19 69.2 0.4 5.2e-19 68.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAG25611.1 - 4.2e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG25611.1 - 0.0025 17.1 0.0 0.0025 17.1 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase RNA_pol_A_CTD PF03118.15 OAG25611.1 - 0.11 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Cwf_Cwc_15 PF04889.12 OAG25611.1 - 1.2 8.8 18.5 1.8 8.2 18.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAG25611.1 - 1.7 6.8 12.2 2.3 6.3 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.26 OAG25614.1 - 0.0074 16.7 8.4 0.024 15.1 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG25614.1 - 0.48 10.9 0.2 0.48 10.9 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger double domain Actin PF00022.19 OAG25616.1 - 1.1e-29 103.2 0.0 2.5e-28 98.8 0.0 2.6 2 1 0 2 2 2 1 Actin PilM_2 PF11104.8 OAG25616.1 - 0.00054 19.1 0.0 0.82 8.6 0.0 2.1 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 OAG25616.1 - 0.0081 15.0 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Nop PF01798.18 OAG25617.1 - 7e-79 264.5 0.1 7e-79 264.5 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAG25617.1 - 1.4e-15 57.4 1.6 1.4e-15 57.4 1.6 2.6 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF760 PF05542.11 OAG25617.1 - 0.11 12.9 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Herpes_UL56 PF04534.12 OAG25617.1 - 1 8.8 6.4 1.9 8.0 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein RNA_pol_Rpb4 PF03874.16 OAG25618.1 - 5e-20 72.1 0.0 7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 zf-MYND PF01753.18 OAG25620.1 - 4.9e-09 36.1 17.7 6.8e-09 35.7 17.7 1.2 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 OAG25620.1 - 0.017 15.5 8.0 0.024 15.0 8.0 1.2 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 OAG25620.1 - 0.036 14.4 14.6 0.062 13.6 14.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Siva PF05458.12 OAG25620.1 - 0.05 13.3 5.4 0.061 13.0 5.4 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PolC_DP2 PF03833.13 OAG25620.1 - 0.13 10.1 4.5 0.13 10.1 4.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_2 PF13639.6 OAG25621.1 - 2.3e-09 37.4 8.5 4.5e-09 36.5 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG25621.1 - 4.1e-08 33.0 4.3 9.1e-08 31.8 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG25621.1 - 6e-06 26.2 7.6 1.4e-05 25.0 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_5 PF17121.5 OAG25621.1 - 0.00026 20.8 5.9 0.0089 15.9 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG25621.1 - 0.00044 20.0 13.6 0.0025 17.6 3.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG25621.1 - 0.00068 19.4 3.9 0.00068 19.4 3.9 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OAG25621.1 - 0.0021 18.3 10.0 0.0056 16.9 9.8 1.8 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG25621.1 - 0.0036 17.3 6.1 0.0085 16.1 5.1 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3552 PF12072.8 OAG25621.1 - 0.0058 16.1 3.4 0.01 15.3 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Prok-RING_4 PF14447.6 OAG25621.1 - 0.01 15.6 13.2 0.031 14.1 4.3 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG25621.1 - 0.028 14.6 3.2 0.028 14.6 3.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAG25621.1 - 0.03 14.3 10.0 0.03 14.3 10.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG25621.1 - 0.14 12.0 18.1 0.21 11.5 14.8 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OAG25621.1 - 0.58 10.4 6.0 1.5 9.1 6.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.6 OAG25621.1 - 0.75 10.0 8.2 0.74 10.0 4.2 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger OmpH PF03938.14 OAG25621.1 - 3.6 7.9 6.5 0.76 10.1 2.6 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GrpB PF04229.14 OAG25623.1 - 8.6e-43 146.3 0.1 1.7e-42 145.3 0.1 1.5 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.7 OAG25623.1 - 6.5e-19 69.0 0.1 1e-18 68.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG25623.1 - 1e-05 25.7 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG25623.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG25623.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG25623.1 - 0.022 14.4 0.0 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase EAF PF09816.9 OAG25625.1 - 1.1e-16 61.0 0.8 1.1e-16 61.0 0.8 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor DUF2681 PF10883.8 OAG25626.1 - 0.00061 20.1 0.0 0.00092 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Imm27 PF15590.6 OAG25626.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 27 DUF998 PF06197.13 OAG25626.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Bys1 PF04681.12 OAG25627.1 - 9.7e-05 22.4 0.1 0.00011 22.2 0.1 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pkinase PF00069.25 OAG25628.1 - 1.3e-16 60.7 0.0 1.9e-11 43.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25628.1 - 2.2e-10 40.3 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG25628.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAG25628.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_2_N PF02837.18 OAG25629.1 - 2.6e-13 50.2 0.2 9.8e-13 48.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 OAG25629.1 - 4.8e-10 39.0 0.0 1.4e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 OAG25629.1 - 3.5e-08 34.1 0.0 1e-07 32.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Acetyltransf_3 PF13302.7 OAG25630.1 - 1.5e-13 51.6 0.0 3.1e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG25630.1 - 4.2e-12 46.3 0.2 6.6e-12 45.7 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG25630.1 - 4.1e-07 30.3 0.1 6.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG25630.1 - 9.4e-06 25.8 0.0 1.8e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG25630.1 - 3.4e-05 23.8 0.1 5.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG25630.1 - 0.0012 18.7 0.1 0.0036 17.2 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 OAG25630.1 - 0.0044 16.7 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S15 PF00312.22 OAG25631.1 - 1.9e-25 88.9 1.3 1.3e-24 86.2 0.2 2.7 3 0 0 3 3 3 1 Ribosomal protein S15 LsmAD PF06741.13 OAG25631.1 - 0.26 11.9 1.8 0.74 10.4 1.8 1.8 1 0 0 1 1 1 0 LsmAD domain Ribosomal_S2 PF00318.20 OAG25632.1 - 2.9e-24 85.5 0.0 6e-14 51.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAG25632.1 - 7.9e-09 36.8 12.9 1.6e-08 35.8 12.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Glyco_hydro_72 PF03198.14 OAG25633.1 - 5.8e-99 331.3 0.2 7.6e-99 330.9 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAG25633.1 - 0.0045 16.5 1.6 0.12 11.7 1.6 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG25633.1 - 0.0088 15.2 0.3 0.025 13.7 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FAD_binding_4 PF01565.23 OAG25634.1 - 1.1e-19 70.6 4.1 1.7e-19 70.0 4.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG25634.1 - 3.5e-13 49.4 0.0 7.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_2 PF00891.18 OAG25635.1 - 2.1e-22 79.5 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAG25635.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 OAG25635.1 - 0.016 15.2 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 OAG25635.1 - 0.046 14.4 0.0 2.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain HTH_31 PF13560.6 OAG25635.1 - 0.059 13.7 0.2 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 OAG25635.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 OAG25635.1 - 0.12 12.7 0.3 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator Ras PF00071.22 OAG25636.1 - 2.2e-38 131.4 0.0 2.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG25636.1 - 2.4e-12 47.1 0.0 4.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAG25636.1 - 0.0032 17.0 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OAG25636.1 - 0.0069 15.9 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family UBX PF00789.20 OAG25637.1 - 4.2e-07 30.1 0.0 9.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Vfa1 PF08432.10 OAG25637.1 - 0.045 14.1 5.2 0.074 13.4 5.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Thioredoxin PF00085.20 OAG25637.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Spc7 PF08317.11 OAG25638.1 - 0.078 11.8 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_S14 PF00253.21 OAG25639.1 - 2e-20 72.3 1.7 2.2e-20 72.2 0.9 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e E3_UFM1_ligase PF09743.9 OAG25640.1 - 6.5e-05 22.7 0.1 0.00015 21.5 0.1 1.5 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 EF-hand_7 PF13499.6 OAG25641.1 - 0.0016 18.8 0.7 2 8.9 0.0 3.5 2 2 2 4 4 4 2 EF-hand domain pair Dockerin_1 PF00404.18 OAG25641.1 - 0.0019 18.4 9.2 3 8.1 3.1 3.9 3 1 0 3 3 3 2 Dockerin type I domain EF-hand_1 PF00036.32 OAG25641.1 - 0.27 10.9 8.7 18 5.2 0.1 4.3 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 OAG25641.1 - 2.1 8.5 9.3 35 4.7 0.1 4.4 4 0 0 4 4 4 0 EF-hand domain Excalibur PF05901.11 OAG25641.1 - 4.4 8.0 8.0 2.6e+02 2.4 0.1 4.7 5 0 0 5 5 5 0 Excalibur calcium-binding domain EF-hand_5 PF13202.6 OAG25641.1 - 7.4 6.3 17.4 11 5.7 0.2 4.3 4 0 0 4 4 4 0 EF hand EI24 PF07264.11 OAG25642.1 - 1.9e-14 54.3 5.8 2.8e-14 53.8 5.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) OFeT_1 PF16955.5 OAG25642.1 - 0.021 14.5 0.1 0.021 14.5 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Alk_phosphatase PF00245.20 OAG25643.1 - 3.7e-76 256.7 1.3 2.1e-75 254.3 1.3 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 OAG25643.1 - 0.00017 21.1 0.1 0.00045 19.7 0.1 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAG25643.1 - 0.00035 20.3 0.1 0.00057 19.6 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAG25643.1 - 0.014 14.7 0.1 0.034 13.5 0.1 1.6 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.17 OAG25643.1 - 0.036 12.7 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FAD_binding_7 PF03441.14 OAG25644.1 - 1e-55 188.4 1.3 2.5e-55 187.1 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG25644.1 - 1.1e-42 145.8 0.0 2.6e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase HET PF06985.11 OAG25645.1 - 3.3e-34 118.3 1.2 8e-34 117.1 1.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 OAG25645.1 - 4.7e-06 27.0 0.0 1.6e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG25645.1 - 0.0025 18.3 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SCO1-SenC PF02630.14 OAG25646.1 - 5.7e-49 165.5 0.0 8.8e-49 164.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAG25646.1 - 0.00099 19.0 0.0 0.0031 17.4 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAG25646.1 - 0.037 14.3 0.0 0.077 13.3 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like AKAP28 PF14469.6 OAG25646.1 - 0.1 12.4 1.1 4.6 7.0 0.0 2.5 3 0 0 3 3 3 0 28 kDa A-kinase anchor NCE101 PF11654.8 OAG25646.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 HET PF06985.11 OAG25647.1 - 4.1e-28 98.6 0.0 6.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RWD PF05773.22 OAG25648.1 - 0.031 14.6 0.2 0.55 10.5 0.2 2.3 1 1 0 1 1 1 0 RWD domain WD40 PF00400.32 OAG25649.1 - 3.1e-19 68.9 6.7 0.00079 20.2 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG25649.1 - 2.2e-17 63.1 0.1 0.00012 22.3 0.0 5.6 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG25649.1 - 1.3e-06 27.8 0.4 0.041 12.9 0.1 3.0 2 1 1 3 3 3 2 Coatomer WD associated region eIF2A PF08662.11 OAG25649.1 - 1.4e-06 28.4 0.5 0.019 14.9 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAG25649.1 - 0.54 10.3 10.7 0.63 10.1 0.2 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 OAG25650.1 - 7.5e-31 107.3 49.7 3.9e-26 91.8 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG25650.1 - 1.4e-16 60.4 26.1 2.8e-13 49.6 6.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter AMP-binding PF00501.28 OAG25651.1 - 6.4e-69 232.6 0.0 8.8e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG25651.1 - 1.5e-42 145.9 0.0 3.2e-42 144.8 0.0 1.5 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 OAG25651.1 - 2.3e-15 56.7 0.0 3.3e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG25651.1 - 6.5e-05 23.8 0.2 0.0003 21.7 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 OAG25652.1 - 1.9e-72 243.9 0.0 8e-72 241.8 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG25652.1 - 1.7e-34 118.4 0.2 3.5e-34 117.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 OAG25652.1 - 1.8e-27 96.7 0.1 3.1e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG25652.1 - 4.8e-22 78.5 0.0 8.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase HTH_51 PF18558.1 OAG25652.1 - 1.8e-20 72.6 0.2 6.2e-20 70.9 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 OAG25652.1 - 2e-15 56.9 3.3 8.1e-07 29.3 1.4 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 OAG25652.1 - 3.9e-13 50.0 0.0 1.8e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG25652.1 - 9.6e-11 42.1 0.0 6.8e-10 39.4 0.0 2.4 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 OAG25652.1 - 5e-10 39.5 0.0 1.4e-07 31.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG25652.1 - 6.4e-08 33.2 0.0 2.9e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG25652.1 - 5.4e-07 29.5 0.0 1.7e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 OAG25652.1 - 5.8e-07 29.1 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 OAG25652.1 - 8.2e-07 29.0 2.6 6.5e-05 22.8 0.2 2.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_11 PF08241.12 OAG25652.1 - 1.4e-06 28.8 0.0 1.1e-05 26.0 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 OAG25652.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 OAG25652.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 OAG25652.1 - 0.22 10.6 0.0 0.43 9.7 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent p450 PF00067.22 OAG25653.1 - 2.1e-62 211.4 0.0 2.7e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3716 PF12511.8 OAG25655.1 - 0.92 9.6 2.8 2.1 8.4 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) MFS_1 PF07690.16 OAG25656.1 - 3.9e-16 58.9 37.8 1.8e-15 56.7 36.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG25656.1 - 0.0086 14.4 7.7 0.02 13.2 1.4 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3325 PF11804.8 OAG25656.1 - 1.3 9.3 6.8 2.1 8.5 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) bZIP_1 PF00170.21 OAG25657.1 - 5.1e-08 32.9 13.2 8.3e-08 32.2 13.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 OAG25657.1 - 6.2e-05 22.9 0.0 6.2e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 OAG25657.1 - 0.0083 15.9 4.1 0.012 15.3 4.1 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 OAG25657.1 - 0.022 15.1 0.2 0.043 14.2 0.2 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 OAG25657.1 - 0.03 14.4 11.7 0.03 14.4 11.7 2.0 2 1 1 3 3 3 0 Basic region leucine zipper NRBF2 PF08961.10 OAG25657.1 - 0.037 13.6 1.9 0.054 13.1 0.7 1.8 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator V_ATPase_I PF01496.19 OAG25657.1 - 0.056 11.4 2.0 0.067 11.1 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PGBA_C PF15437.6 OAG25657.1 - 0.072 13.5 6.7 0.18 12.2 6.7 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal bZIP_Maf PF03131.17 OAG25657.1 - 0.072 13.6 12.9 0.13 12.8 12.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor GvpL_GvpF PF06386.11 OAG25657.1 - 0.18 11.7 5.7 0.31 10.9 5.7 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF790 PF05626.11 OAG25657.1 - 0.27 9.9 2.1 0.38 9.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) ADIP PF11559.8 OAG25657.1 - 0.37 10.9 11.8 0.63 10.1 11.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OAG25657.1 - 0.7 10.4 8.2 1.2 9.7 8.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 OAG25657.1 - 1.6 8.8 4.6 2.5 8.2 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phosducin PF02114.16 OAG25658.1 - 1.3e-10 40.7 0.1 1.6e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Phosducin HET PF06985.11 OAG25659.1 - 8.8e-14 52.1 5.3 4.7e-12 46.5 3.3 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 OAG25660.1 - 3.7e-26 92.2 0.3 6.3e-25 88.2 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25660.1 - 8.4e-06 25.2 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG25660.1 - 2.3e-05 23.8 0.0 0.079 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG25660.1 - 2.6e-05 24.0 0.1 0.012 15.3 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG25660.1 - 8.4e-05 22.7 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG25660.1 - 0.00091 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG25660.1 - 0.0019 18.7 0.0 0.066 13.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG25660.1 - 0.062 12.3 0.0 0.77 8.8 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Amidohydro_1 PF01979.20 OAG25661.1 - 7.8e-16 58.3 2.9 1e-15 57.9 2.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG25661.1 - 6.5e-08 32.5 3.2 2.9e-07 30.3 0.1 2.5 2 1 1 3 3 3 1 Amidohydrolase family GMC_oxred_C PF05199.13 OAG25662.1 - 8.6e-29 100.9 0.0 1.4e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG25662.1 - 7.9e-24 84.5 0.0 2.9e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG25662.1 - 0.00047 19.5 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG25662.1 - 0.00099 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG25662.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG25662.1 - 0.0014 17.8 0.2 0.002 17.2 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG25662.1 - 0.0029 16.9 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG25662.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 OAG25662.1 - 0.021 14.5 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 OAG25662.1 - 0.034 12.9 0.1 0.081 11.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF1100 PF06500.11 OAG25664.1 - 1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 OAG25664.1 - 0.0015 19.1 0.9 0.0025 18.4 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG25664.1 - 0.0016 17.8 0.1 0.0043 16.3 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG25664.1 - 0.003 17.3 0.2 0.61 9.7 0.2 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 OAG25664.1 - 0.0044 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4398 PF14346.6 OAG25664.1 - 0.14 12.8 2.6 0.3 11.7 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) TRI12 PF06609.13 OAG25665.1 - 4e-19 68.5 17.2 5.5e-19 68.0 17.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG25665.1 - 6.1e-14 51.7 61.2 2.3e-11 43.2 52.1 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG25666.1 - 4.1e-15 55.5 1.7 4.1e-15 55.5 1.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG25666.1 - 1.5e-08 34.6 13.2 0.00029 21.1 4.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25666.1 - 7.1e-05 23.3 19.5 0.0065 17.2 3.3 4.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG25666.1 - 0.00012 22.3 20.1 0.00014 22.2 1.9 5.0 4 1 0 4 4 4 2 Zinc-finger double domain Zn_clus PF00172.18 OAG25666.1 - 0.00031 20.8 12.6 0.00095 19.2 12.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.12 OAG25666.1 - 0.0024 18.1 2.3 0.0024 18.1 2.3 2.9 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OAG25666.1 - 0.044 14.2 2.5 3.2 8.3 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OAG25666.1 - 0.046 13.5 5.7 0.8 9.5 2.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Thymopoietin PF08198.11 OAG25666.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Thymopoietin protein Peptidase_S15 PF02129.18 OAG25667.1 - 2.5e-31 109.2 3.8 4.5e-31 108.4 0.5 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG25667.1 - 1e-25 91.0 0.0 2.2e-25 90.0 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Radial_spoke_3 PF06098.11 OAG25668.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Aldo_ket_red PF00248.21 OAG25669.1 - 5.6e-27 94.7 0.0 8.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 OAG25670.1 - 1.7e-70 238.0 0.0 2.2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG25670.1 - 0.00011 21.6 0.4 0.073 12.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG25670.1 - 0.00061 19.1 0.1 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG25670.1 - 0.0011 19.1 0.1 0.003 17.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG25670.1 - 0.0019 17.0 0.0 0.18 10.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAG25670.1 - 0.0048 16.5 3.7 0.25 10.9 0.9 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG25670.1 - 0.015 14.4 0.1 2.8 6.9 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 OAG25670.1 - 0.08 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family GST_N PF02798.20 OAG25671.1 - 1.9e-16 60.1 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG25671.1 - 4.9e-14 52.5 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG25671.1 - 2.6e-11 43.6 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG25671.1 - 6.5e-09 36.0 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG25671.1 - 3.3e-08 33.4 0.1 6.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG25671.1 - 3.9e-05 23.8 0.0 6.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 OAG25671.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N_5 PF18485.1 OAG25671.1 - 0.066 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SSF PF00474.17 OAG25672.1 - 0.0004 19.4 24.0 0.0063 15.4 24.0 2.3 1 1 0 1 1 1 1 Sodium:solute symporter family PX PF00787.24 OAG25673.1 - 5.8e-27 93.9 0.0 6.7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 PX domain LysM PF01476.20 OAG25674.1 - 3.4e-10 39.8 0.0 0.00065 19.7 0.0 2.5 2 0 0 2 2 2 2 LysM domain Catalase PF00199.19 OAG25675.1 - 1.3e-05 24.5 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Catalase Pyrophosphatase PF00719.19 OAG25675.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Inorganic pyrophosphatase Amidohydro_2 PF04909.14 OAG25676.1 - 2.3e-14 53.9 1.1 5.1e-14 52.7 1.1 1.6 1 1 0 1 1 1 1 Amidohydrolase PAPS_reduct PF01507.19 OAG25677.1 - 8.1e-42 143.2 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.17 OAG25678.1 - 8.1e-89 296.7 0.1 1.8e-88 295.5 0.0 1.6 2 0 0 2 2 2 1 ATP-sulfurylase APS_kinase PF01583.20 OAG25678.1 - 5e-56 189.0 0.0 8.6e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAG25678.1 - 1.8e-53 180.5 0.0 2.9e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain DUF5585 PF17823.1 OAG25679.1 - 0.011 14.8 16.9 0.011 14.7 16.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) TamB PF04357.13 OAG25679.1 - 0.38 9.9 5.3 0.42 9.8 5.3 1.0 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex DUF3185 PF11381.8 OAG25679.1 - 2.2 8.4 7.0 10 6.2 7.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) HET PF06985.11 OAG25680.1 - 4.9e-29 101.6 0.0 1e-28 100.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ald_Xan_dh_C2 PF02738.18 OAG25680.1 - 0.21 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase NmrA PF05368.13 OAG25682.1 - 7.9e-39 133.6 0.2 1.7e-38 132.5 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG25682.1 - 2.3e-09 37.4 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG25682.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG25682.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 OAG25682.1 - 0.0033 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG25682.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3510 PF12022.8 OAG25683.1 - 0.074 13.4 4.2 0.06 13.7 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) ATP-synt_DE_N PF02823.16 OAG25684.1 - 1.8e-17 63.0 0.1 4e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DASH_Spc19 PF08287.11 OAG25685.1 - 2.9e-52 176.7 2.5 2.9e-52 176.7 2.5 1.4 2 0 0 2 2 2 1 Spc19 COG2 PF06148.11 OAG25685.1 - 0.52 10.4 4.1 1.3 9.1 0.4 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_J PF04911.12 OAG25686.1 - 3.8e-28 96.8 1.6 4.2e-28 96.7 1.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain Pkinase PF00069.25 OAG25687.1 - 2.2e-26 92.8 0.0 2.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25687.1 - 6e-14 52.0 0.0 8.2e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG25687.1 - 4.1e-09 35.7 0.0 5.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG25687.1 - 0.00016 21.7 0.0 0.0015 18.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1923 PF09083.10 OAG25687.1 - 0.094 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) HLH PF00010.26 OAG25688.1 - 1.3e-13 50.7 0.6 2.5e-13 49.8 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med28 PF11594.8 OAG25688.1 - 0.0034 17.4 0.2 0.0075 16.4 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 28 FAM76 PF16046.5 OAG25688.1 - 0.0072 15.7 3.8 0.0072 15.7 3.8 1.5 2 0 0 2 2 2 1 FAM76 protein ZapB PF06005.12 OAG25688.1 - 0.02 15.3 2.4 0.058 13.8 2.4 1.8 1 0 0 1 1 1 0 Cell division protein ZapB EloA-BP1 PF15870.5 OAG25688.1 - 0.023 14.9 1.5 0.05 13.9 1.5 1.5 1 0 0 1 1 1 0 ElonginA binding-protein 1 RTX PF02382.15 OAG25688.1 - 0.06 13.0 0.5 0.096 12.4 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein MPS2 PF17060.5 OAG25688.1 - 0.12 11.6 3.2 0.22 10.7 3.2 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 CC2-LZ PF16516.5 OAG25688.1 - 0.12 12.7 3.1 0.25 11.7 3.1 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DivIC PF04977.15 OAG25688.1 - 0.36 10.6 2.5 0.85 9.4 2.5 1.6 1 0 0 1 1 1 0 Septum formation initiator End3 PF12761.7 OAG25688.1 - 0.43 10.7 5.9 1.2 9.3 5.9 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 G-gamma PF00631.22 OAG25689.1 - 3.2e-21 75.1 0.1 3.7e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 OAG25690.1 - 1.8e-08 34.9 1.7 1.5e-07 31.9 0.0 3.2 3 0 0 3 3 3 1 PCI domain HET PF06985.11 OAG25691.1 - 9.4e-14 52.0 3.7 1e-10 42.1 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Clr5 PF14420.6 OAG25692.1 - 3.1e-12 46.5 8.3 1.9e-11 44.0 8.4 2.4 2 0 0 2 2 2 1 Clr5 domain CBM49 PF09478.10 OAG25693.1 - 0.093 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Tautomerase_3 PF14832.6 OAG25694.1 - 8.8e-50 168.5 0.0 9.8e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.21 OAG25695.1 - 1.3e-15 57.6 0.0 5.1e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG25695.1 - 1.1e-13 50.8 0.0 5.7e-13 48.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG25695.1 - 1.5e-11 43.9 0.0 2.6e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG25695.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG25695.1 - 3.5e-09 36.5 0.0 6.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG25695.1 - 1.3e-07 31.1 0.0 1.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG25695.1 - 1.3e-05 24.9 0.1 2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG25695.1 - 0.013 14.9 0.0 0.15 11.5 0.0 2.4 3 0 0 3 3 3 0 short chain dehydrogenase Alpha_adaptin_C PF02296.16 OAG25696.1 - 0.069 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain AA_permease PF00324.21 OAG25697.1 - 4.7e-45 154.1 24.3 7.3e-45 153.5 24.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG25697.1 - 1.7e-22 79.9 25.5 2.1e-22 79.5 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.19 OAG25698.1 - 1.7e-14 53.9 0.0 3.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG25698.1 - 1.4e-09 38.6 0.2 3.6e-09 37.3 0.2 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG25698.1 - 0.00022 20.5 1.0 0.00053 19.2 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25698.1 - 0.006 15.9 0.3 0.012 14.9 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG25698.1 - 0.0082 15.5 1.2 0.013 14.8 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG25698.1 - 0.034 14.4 5.7 0.068 13.4 0.9 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG25698.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG25698.1 - 0.11 13.1 0.0 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG25698.1 - 0.16 11.2 0.2 0.24 10.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain PfkB PF00294.24 OAG25700.1 - 1.4e-15 57.4 0.0 9.4e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase SARAF PF06682.12 OAG25701.1 - 0.01 15.5 2.7 0.013 15.2 2.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis 7tm_1 PF00001.21 OAG25701.1 - 0.013 14.8 0.6 0.013 14.8 0.6 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) OAD_gamma PF04277.13 OAG25701.1 - 0.086 13.4 0.1 0.23 12.1 0.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2615 PF11027.8 OAG25701.1 - 0.43 10.7 0.0 0.43 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF485 PF04341.12 OAG25701.1 - 6.6 6.8 8.7 0.61 10.1 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 NAD_binding_1 PF00175.21 OAG25702.1 - 1.2e-06 29.2 0.0 0.013 16.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG25702.1 - 0.0016 18.6 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAG25702.1 - 0.079 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Hydrolase_4 PF12146.8 OAG25703.1 - 5.2e-52 176.5 0.0 6.4e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG25703.1 - 4.1e-15 56.1 0.0 5e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG25703.1 - 1.5e-12 48.6 0.0 1.9e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG25703.1 - 0.0022 17.5 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 OAG25703.1 - 0.0026 16.9 0.0 0.0083 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Cation_efflux PF01545.21 OAG25704.1 - 2.2e-52 177.7 2.2 2.7e-52 177.4 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG25704.1 - 1.3e-05 25.2 0.2 3.1e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter UPF0147 PF03685.13 OAG25704.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) FGGY_C PF02782.16 OAG25705.1 - 1.3e-28 100.1 0.0 2.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG25705.1 - 1.4e-16 60.8 0.0 2.2e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HET PF06985.11 OAG25706.1 - 1e-28 100.5 0.0 2.2e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG25707.1 - 1.2e-06 28.9 0.8 0.00042 20.7 0.0 2.8 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4231 PF14015.6 OAG25708.1 - 0.31 11.5 5.7 9.7 6.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Myb_DNA-binding PF00249.31 OAG25709.1 - 8e-14 51.6 0.0 9.8e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG25709.1 - 2.5e-08 34.1 0.0 0.00098 19.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OAG25709.1 - 0.00013 21.9 0.0 0.0091 16.0 0.0 2.5 2 0 0 2 2 2 1 SLIDE CCDC106 PF15794.5 OAG25709.1 - 1.1 8.9 6.0 0.48 10.1 2.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 AhpC-TSA PF00578.21 OAG25710.1 - 1.2e-32 112.5 0.0 1.6e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG25710.1 - 5.5e-15 55.4 0.0 7.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAG25710.1 - 6.4e-15 54.7 0.1 1.1e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Acatn PF13000.7 OAG25711.1 - 3.8e-163 543.9 18.9 2e-86 290.7 6.8 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 OAG25712.1 - 3.3e-56 190.6 0.1 6.3e-56 189.7 0.0 1.5 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Glyco_hydro_79C PF16862.5 OAG25713.1 - 0.098 13.6 0.0 0.12 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_18 PF00704.28 OAG25714.1 - 8.8e-85 285.2 3.3 1e-84 284.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LIAS_N PF16881.5 OAG25715.1 - 1.2e-19 70.8 0.0 2.4e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAG25715.1 - 4.5e-13 49.9 0.0 7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UBA_5 PF16577.5 OAG25715.1 - 0.026 14.7 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 UBA domain Adaptin_N PF01602.20 OAG25716.1 - 5.3e-114 381.7 0.0 7.2e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAG25716.1 - 2.1e-57 193.5 4.1 4.8e-57 192.4 4.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAG25716.1 - 1.2e-34 118.8 0.2 3.7e-34 117.3 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAG25716.1 - 1e-17 64.2 0.9 6.3e-10 39.3 0.0 5.7 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 OAG25716.1 - 3.1e-07 30.6 9.6 0.045 13.8 0.2 4.6 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG25716.1 - 0.031 14.8 0.9 0.54 10.8 0.1 3.0 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 OAG25716.1 - 0.057 13.7 7.5 4.3 7.9 0.3 5.7 6 0 0 6 6 6 0 HEAT repeat HEAT_PBS PF03130.16 OAG25716.1 - 0.21 12.4 3.1 41 5.2 0.0 4.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat SET PF00856.28 OAG25717.1 - 8.1e-17 62.1 0.0 1.6e-16 61.1 0.0 1.5 2 0 0 2 2 2 1 SET domain Coq4 PF05019.13 OAG25718.1 - 3.5e-94 314.2 0.0 4.3e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Zn_clus PF00172.18 OAG25719.1 - 1.5e-10 41.1 6.0 3.5e-10 39.8 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 OAG25719.1 - 0.0024 17.8 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension adh_short PF00106.25 OAG25721.1 - 6.6e-35 120.3 0.2 9.3e-35 119.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25721.1 - 6.7e-28 97.8 0.1 8.7e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25721.1 - 1.2e-07 31.8 0.1 1.5e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG25721.1 - 0.097 12.1 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Annexin PF00191.20 OAG25722.1 - 4e-20 71.6 3.9 0.00026 21.0 0.0 4.4 4 0 0 4 4 4 4 Annexin Hepatitis_core PF00906.20 OAG25722.1 - 0.098 12.2 1.8 0.29 10.7 1.6 1.8 2 0 0 2 2 2 0 Hepatitis core antigen TFIIA PF03153.13 OAG25722.1 - 2.1 8.3 10.4 3.5 7.5 10.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SQS_PSY PF00494.19 OAG25724.1 - 3.4e-65 220.2 0.2 4.5e-65 219.8 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase GPI2 PF06432.11 OAG25724.1 - 2.1e-63 214.4 0.2 4.7e-63 213.3 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase RPE65 PF03055.15 OAG25725.1 - 1.4e-115 387.2 0.0 1.6e-115 386.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Bac_rhodopsin PF01036.18 OAG25726.1 - 1.1e-58 198.5 9.5 1.3e-58 198.3 9.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Wzy_C PF04932.15 OAG25726.1 - 0.16 11.6 0.2 0.16 11.6 0.2 2.2 2 0 0 2 2 2 0 O-Antigen ligase Arteri_Gl PF00951.18 OAG25726.1 - 0.49 10.2 3.7 0.72 9.6 2.8 1.7 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Imp-YgjV PF10688.9 OAG25726.1 - 0.63 9.8 10.7 0.28 11.0 6.9 2.0 2 0 0 2 2 2 0 Bacterial inner membrane protein DUF3810 PF12725.7 OAG25726.1 - 6.5 6.0 6.6 14 4.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Amino_oxidase PF01593.24 OAG25727.1 - 6.5e-22 78.4 0.0 5.2e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG25727.1 - 1e-13 51.3 0.1 3.4e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG25727.1 - 2.7e-10 40.4 0.1 2.1e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG25727.1 - 1.2e-07 31.3 0.1 7.1e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG25727.1 - 2.1e-07 30.4 2.6 0.00027 20.1 3.5 2.6 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 OAG25727.1 - 7.5e-05 21.6 0.2 0.0022 16.8 0.6 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG25727.1 - 0.00022 20.7 2.5 0.00051 19.5 2.5 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG25727.1 - 0.0035 17.9 2.8 0.029 14.9 1.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG25727.1 - 0.0096 15.2 0.3 0.045 13.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG25727.1 - 0.01 15.1 0.7 0.019 14.2 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG25727.1 - 0.03 14.3 0.4 0.083 12.9 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG25727.1 - 0.068 12.4 0.5 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 OAG25727.1 - 0.09 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG25727.1 - 0.096 11.7 2.2 0.15 11.1 2.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 OAG25727.1 - 0.2 11.9 0.1 0.36 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 OAG25727.1 - 0.2 10.6 1.3 0.48 9.4 0.6 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.25 OAG25727.1 - 0.32 10.4 0.6 0.53 9.7 0.6 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 OAG25727.1 - 0.42 10.5 0.9 0.72 9.7 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_Phos_2 PF00328.22 OAG25728.1 - 3.7e-28 99.0 0.0 4.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1798 PF08807.10 OAG25728.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF1192 PF06698.11 OAG25729.1 - 0.056 13.5 0.6 2.3 8.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PKcGMP_CC PF16808.5 OAG25729.1 - 0.11 12.3 5.1 0.15 12.0 0.0 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4349 PF14257.6 OAG25729.1 - 0.14 11.6 7.3 2.5 7.5 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4349) DUF641 PF04859.12 OAG25729.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) IFT20 PF14931.6 OAG25729.1 - 1.4 9.1 5.4 6.6 6.9 0.3 3.3 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 UPF0242 PF06785.11 OAG25729.1 - 4.2 7.4 9.2 12 6.0 0.5 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_43 PF04616.14 OAG25730.1 - 1.4e-91 306.8 1.2 2.7e-91 305.9 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Vps5 PF09325.10 OAG25730.1 - 8.9e-81 270.9 5.0 1.6e-80 270.1 5.0 1.4 1 0 0 1 1 1 1 Vps5 C terminal like GH43_C2 PF17851.1 OAG25730.1 - 2e-42 145.2 0.0 3.4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PX PF00787.24 OAG25730.1 - 1.2e-25 89.7 0.0 2.6e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.9 OAG25730.1 - 0.0022 17.2 0.4 0.0038 16.4 0.4 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Glyco_hydro_32N PF00251.20 OAG25730.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain BAR_3 PF16746.5 OAG25730.1 - 0.08 12.6 4.1 0.56 9.9 1.9 2.2 1 1 1 2 2 2 0 BAR domain of APPL family DUF5321 PF17254.2 OAG25732.1 - 3.9e-60 201.9 1.9 4.8e-60 201.6 1.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Moulting_cycle PF04870.16 OAG25732.1 - 0.045 13.0 1.3 0.067 12.5 1.3 1.2 1 0 0 1 1 1 0 Moulting cycle DUF3326 PF11805.8 OAG25732.1 - 0.17 10.7 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Kelch_5 PF13854.6 OAG25734.1 - 6e-26 90.0 5.0 2.5e-08 33.7 0.1 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OAG25734.1 - 4.1e-25 87.2 6.0 2.4e-09 37.2 0.5 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OAG25734.1 - 1.7e-24 85.6 8.0 2e-05 24.7 0.2 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG25734.1 - 1.7e-22 79.2 9.3 8.3e-06 25.7 1.2 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG25734.1 - 8.3e-16 57.3 7.0 2.6e-09 36.5 0.4 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OAG25734.1 - 6.9e-12 44.9 7.6 6.6e-09 35.4 0.3 4.6 5 0 0 5 5 5 2 Kelch motif DUF1664 PF07889.12 OAG25734.1 - 0.041 13.9 39.5 0.44 10.6 3.4 5.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Strep_SA_rep PF06696.11 OAG25734.1 - 0.097 12.7 2.3 36 4.5 0.1 3.9 4 0 0 4 4 4 0 Streptococcal surface antigen repeat Raptor_N PF14538.6 OAG25735.1 - 3.3e-65 218.5 0.0 6.3e-65 217.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 OAG25735.1 - 7.6e-05 22.9 0.1 6.3 7.2 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG25735.1 - 0.00012 22.8 13.0 1.5 9.8 0.0 6.1 7 1 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAG25735.1 - 0.00026 21.0 0.2 0.1 12.6 0.0 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 OAG25735.1 - 0.015 15.3 0.2 0.03 14.4 0.2 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 OAG25735.1 - 0.11 12.9 4.7 7.1 7.2 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat tRNA-synt_2 PF00152.20 OAG25736.1 - 1.4e-72 244.4 0.0 1.9e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG25736.1 - 0.0001 22.2 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG25736.1 - 0.0075 15.8 0.2 0.55 9.7 0.2 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Rrp40_N PF18311.1 OAG25737.1 - 3.5e-16 58.8 0.4 7e-16 57.9 0.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 OAG25737.1 - 2.1e-13 50.4 0.6 3.3e-13 49.8 0.6 1.3 1 0 0 1 1 1 1 KH domain HSP70 PF00012.20 OAG25738.1 - 4.9e-79 266.1 0.8 7e-79 265.6 0.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG25738.1 - 2.2e-08 33.3 0.1 3.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Cwf_Cwc_15 PF04889.12 OAG25738.1 - 0.0057 16.4 3.0 0.01 15.6 3.0 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PilM_2 PF11104.8 OAG25738.1 - 0.016 14.3 0.2 5.2 6.0 0.0 2.6 2 1 0 2 2 2 0 Type IV pilus assembly protein PilM; FAM176 PF14851.6 OAG25738.1 - 0.13 12.0 2.0 0.29 10.8 2.0 1.6 1 0 0 1 1 1 0 FAM176 family DUF3221 PF11518.8 OAG25738.1 - 0.54 10.6 4.6 0.21 12.0 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DNA_pol_phi PF04931.13 OAG25738.1 - 2 6.4 5.9 3 5.8 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAG25738.1 - 8.4 5.6 7.2 14 4.9 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.7 OAG25739.1 - 3.5e-09 36.4 0.1 9.4e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG25739.1 - 0.02 14.8 0.0 0.097 12.6 0.0 2.2 1 0 0 1 1 1 0 F-box domain Lactonase PF10282.9 OAG25740.1 - 7.6e-61 206.3 0.3 9.5e-61 205.9 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Hydrolase_6 PF13344.6 OAG25741.1 - 3.9e-23 81.5 0.0 2.1e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG25741.1 - 4.5e-18 65.1 0.1 1.5e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG25741.1 - 0.00018 21.9 0.1 1.7 8.9 0.0 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.25 OAG25742.1 - 1.9e-07 31.3 0.0 1.5e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG25742.1 - 2.3e-07 31.1 0.0 1.1e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG25742.1 - 0.00068 19.6 0.0 0.0022 17.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.28 OAG25743.1 - 1.2e-14 55.1 9.5 7.3e-14 52.5 0.1 3.7 3 1 0 3 3 3 2 SET domain AWS PF17907.1 OAG25743.1 - 1.1e-05 25.3 5.4 1.1e-05 25.3 5.4 2.4 2 0 0 2 2 2 1 AWS domain DHHC PF01529.20 OAG25744.1 - 1.9e-35 121.9 3.5 4.3e-35 120.7 3.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase B12D PF06522.11 OAG25745.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3446 PF11928.8 OAG25745.1 - 0.046 14.0 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain tRNA-synt_His PF13393.6 OAG25746.1 - 6.1e-44 150.5 0.0 7.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAG25746.1 - 5.2e-15 55.4 0.0 9.7e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OAG25746.1 - 4.7e-05 23.0 0.0 7.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OAG25746.1 - 0.0026 16.9 0.0 0.046 12.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) SIP1 PF04938.12 OAG25747.1 - 5.5e-16 58.9 1.6 2.6e-15 56.7 0.0 2.7 4 0 0 4 4 4 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) CDP-OH_P_transf PF01066.21 OAG25748.1 - 2.9e-16 60.0 0.1 2.9e-16 60.0 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 OAG25749.1 - 7.7e-40 135.2 0.4 7.5e-28 96.7 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP RhoGAP PF00620.27 OAG25750.1 - 4.2e-49 166.3 0.0 8.2e-49 165.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OAG25750.1 - 1.1e-10 41.6 0.6 3.3e-10 40.1 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 OAG25750.1 - 0.012 16.0 9.7 0.028 14.8 9.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) VPS38 PF17649.1 OAG25750.1 - 0.064 12.1 1.7 0.099 11.5 1.7 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Putative_PNPOx PF01243.20 OAG25751.1 - 2.1e-12 47.0 0.0 7.3e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 OAG25751.1 - 0.029 14.4 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase MATalpha_HMGbox PF04769.12 OAG25752.1 - 3.9e-57 192.8 0.0 5.9e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Exo_endo_phos PF03372.23 OAG25753.1 - 2.5e-09 37.0 0.0 4.8e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAG25753.1 - 2.8e-06 27.3 4.0 8.2e-06 25.8 4.0 1.8 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAG25753.1 - 0.045 13.6 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase COX6A PF02046.15 OAG25754.1 - 3.2e-47 159.6 4.3 3.9e-47 159.3 4.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 OAG25755.1 - 3.4e-30 104.0 4.5 3.4e-30 104.0 4.5 3.6 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 OAG25755.1 - 1.8e-06 27.8 0.5 2.6e-05 24.0 0.7 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 OAG25755.1 - 6.7e-06 26.3 11.8 0.002 18.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG25755.1 - 0.00016 22.1 4.8 0.63 10.6 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG25755.1 - 0.0038 17.2 0.5 26 5.2 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG25755.1 - 0.004 17.9 7.0 8.6 7.5 0.0 5.9 6 2 1 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG25755.1 - 0.0096 16.1 0.6 36 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG25755.1 - 0.0098 15.7 0.6 49 4.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG25755.1 - 0.01 15.7 0.1 9.1 6.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG25755.1 - 0.012 15.6 0.2 23 5.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG25755.1 - 0.42 11.3 1.4 1.5e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CIA30 PF08547.12 OAG25756.1 - 1.3e-45 155.2 0.0 1.7e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Mito_carr PF00153.27 OAG25757.1 - 1.3e-72 239.8 2.6 2.3e-23 81.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim44 PF04280.15 OAG25758.1 - 4.5e-06 26.8 0.0 0.00029 21.0 0.0 2.8 3 0 0 3 3 3 1 Tim44-like domain MBA1 PF07961.11 OAG25758.1 - 6.4e-06 25.4 0.2 4.8e-05 22.5 0.1 2.4 2 1 0 2 2 2 1 MBA1-like protein SUI1 PF01253.22 OAG25759.1 - 6.4e-28 97.1 3.8 9.2e-28 96.6 3.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 OAG25759.1 - 0.12 12.6 0.4 0.22 11.8 0.2 1.5 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain UPF0139 PF03669.13 OAG25760.1 - 8.8e-08 31.9 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.10 OAG25761.1 - 9.8e-25 86.6 0.2 2.5e-24 85.3 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 SAICAR_synt PF01259.18 OAG25762.1 - 5.9e-98 327.5 0.0 6.9e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Atg29_N PF18388.1 OAG25763.1 - 7.6e-23 80.1 1.3 1.7e-22 78.9 1.3 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain SUR7 PF06687.12 OAG25765.1 - 2.3e-39 135.2 5.0 2.9e-39 134.9 5.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 OAG25765.1 - 6.3e-06 25.9 1.1 9.3e-06 25.3 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Clc-like PF07062.12 OAG25765.1 - 7.9e-05 22.2 4.1 0.00012 21.6 4.1 1.3 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 OAG25765.1 - 0.077 12.8 6.5 0.14 12.0 6.5 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein Claudin_2 PF13903.6 OAG25765.1 - 7 6.4 14.7 0.6 9.8 9.1 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2157 PF09925.9 OAG25765.1 - 9.5 6.0 16.8 0.3 10.9 10.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Rogdi_lz PF10259.9 OAG25766.1 - 1e-86 290.7 0.0 1.2e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein TP_methylase PF00590.20 OAG25767.1 - 6.1e-49 166.8 0.2 1.1e-48 166.1 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 OAG25767.1 - 3.6e-12 46.6 0.0 6.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 OAG25767.1 - 1.9e-11 43.2 0.2 4.4e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 OAG25767.1 - 5e-11 42.1 0.5 1e-09 37.9 0.5 2.3 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal DUF3433 PF11915.8 OAG25768.1 - 2.9e-33 114.2 21.0 1.4e-23 83.1 6.4 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pex14_N PF04695.13 OAG25768.1 - 0.032 14.9 0.5 0.032 14.9 0.5 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TM231 PF10149.9 OAG25768.1 - 0.082 12.2 0.7 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 231 Phage_Coat_B PF05356.11 OAG25770.1 - 0.0012 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Phage Coat protein B SKG6 PF08693.10 OAG25770.1 - 0.0051 16.2 1.9 0.0082 15.5 1.9 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rick_17kDa_Anti PF05433.15 OAG25770.1 - 0.027 14.3 6.1 0.072 13.0 6.1 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Adeno_E3_CR2 PF02439.15 OAG25770.1 - 0.031 14.0 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OAG25770.1 - 0.039 14.8 0.0 0.067 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OAG25770.1 - 0.046 13.6 0.1 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Yip1 PF04893.17 OAG25770.1 - 0.074 12.8 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain TMEM51 PF15345.6 OAG25770.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Gly-zipper_Omp PF13488.6 OAG25770.1 - 1.3 9.0 12.4 0.11 12.5 7.1 1.9 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 OAG25770.1 - 5.5 6.8 11.0 0.46 10.3 5.8 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper Podoplanin PF05808.11 OAG25770.1 - 8.3 6.5 8.1 18 5.4 7.8 1.7 1 1 0 1 1 1 0 Podoplanin stn_TNFRSF12A PF12191.8 OAG25771.1 - 1.6e-05 25.1 0.8 4e-05 23.8 0.7 1.6 1 1 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM132D_C PF15706.5 OAG25771.1 - 0.062 13.1 0.2 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SprA-related PF12118.8 OAG25771.1 - 4.8 6.2 11.5 7.7 5.5 11.5 1.2 1 0 0 1 1 1 0 SprA-related family MGC-24 PF05283.11 OAG25771.1 - 8.7 6.8 15.4 23 5.4 15.4 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1688 PF07958.11 OAG25772.1 - 1.6e-171 570.7 0.0 1.8e-171 570.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 OAG25772.1 - 1.2e-05 25.0 0.0 0.043 13.4 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family PDEase_I PF00233.19 OAG25773.1 - 3.4e-67 226.7 0.0 4.9e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-C2H2_2 PF12756.7 OAG25775.1 - 2.5 8.5 8.7 2.7 8.4 0.1 3.4 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) tRNA-synt_1 PF00133.22 OAG25776.1 - 2.9e-160 534.5 0.6 3.9e-160 534.0 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) UPF0183 PF03676.14 OAG25776.1 - 3.1e-42 145.3 0.0 1.6e-30 106.7 0.0 3.2 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) tRNA-synt_1g PF09334.11 OAG25776.1 - 3.3e-20 72.2 5.3 2.4e-14 52.9 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG25776.1 - 9.5e-20 71.1 0.0 1.8e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG25776.1 - 0.024 14.0 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 OAG25776.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 OAG25776.1 - 0.092 12.6 6.9 0.23 11.4 6.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Kinesin PF00225.23 OAG25777.1 - 1.1e-109 366.5 0.1 1.1e-109 366.5 0.1 2.5 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 OAG25777.1 - 3.8e-24 85.3 0.4 3.3e-23 82.3 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 OAG25777.1 - 7e-10 39.4 0.1 7e-10 39.4 0.1 5.3 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding IL10 PF00726.17 OAG25777.1 - 0.016 14.8 0.6 0.016 14.8 0.6 2.6 3 0 0 3 3 3 0 Interleukin 10 Apolipoprotein PF01442.18 OAG25777.1 - 8.5 6.2 63.5 0.86 9.4 25.3 4.8 1 1 3 4 4 4 0 Apolipoprotein A1/A4/E domain Proteasome PF00227.26 OAG25778.1 - 0.027 13.9 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 Proteasome subunit Cep57_MT_bd PF06657.13 OAG25779.1 - 3.2 8.3 8.6 11 6.5 1.8 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mitochondr_Som1 PF11093.8 OAG25780.1 - 6.4e-05 22.9 0.2 0.00024 21.0 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial export protein Som1 eIF3_p135 PF12807.7 OAG25780.1 - 0.031 14.3 1.2 0.081 13.0 0.1 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 RPAP1_N PF08621.10 OAG25780.1 - 0.044 13.6 2.9 1.9 8.3 0.4 2.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal p450 PF00067.22 OAG25781.1 - 2.5e-68 230.9 0.0 3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3262 PF11660.8 OAG25781.1 - 0.48 10.9 1.7 0.64 10.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) DNA_pol_B PF00136.21 OAG25784.1 - 2e-105 353.1 0.0 2.7e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG25784.1 - 4.4e-26 91.8 0.1 2.4e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAG25784.1 - 6.6e-18 64.9 3.1 6.6e-18 64.9 3.1 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 OAG25784.1 - 0.13 11.1 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Slu7 PF11708.8 OAG25785.1 - 1.3e-78 264.4 23.2 1.3e-78 264.4 23.2 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor RC-P840_PscD PF10657.9 OAG25785.1 - 0.036 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD zf-CCHC_4 PF14392.6 OAG25785.1 - 0.045 13.5 0.5 0.08 12.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 OAG25785.1 - 0.63 10.2 3.1 1.1 9.4 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle ANTH PF07651.16 OAG25786.1 - 5.3e-80 268.4 0.0 5.3e-80 268.4 0.0 2.9 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 OAG25786.1 - 7.7e-56 188.6 7.2 7.7e-56 188.6 7.2 5.8 3 2 4 7 7 7 2 I/LWEQ domain Nnf1 PF03980.14 OAG25788.1 - 5.9e-29 100.7 0.7 1.2e-28 99.7 0.7 1.5 1 0 0 1 1 1 1 Nnf1 SCAB_CC PF16712.5 OAG25788.1 - 0.0059 16.5 1.9 0.19 11.6 0.6 2.3 2 0 0 2 2 2 1 Coiled-coil regions of plant-specific actin-binding protein Cytochrom_B562 PF07361.11 OAG25788.1 - 0.0061 17.2 3.0 0.011 16.3 1.2 2.1 2 1 0 2 2 2 1 Cytochrome b562 DUF892 PF05974.12 OAG25788.1 - 0.012 15.7 2.1 0.012 15.7 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) HeLo PF14479.6 OAG25788.1 - 0.036 13.9 0.6 0.059 13.2 0.6 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Med30 PF11315.8 OAG25788.1 - 0.046 13.9 3.0 0.5 10.6 0.6 2.5 1 1 1 2 2 2 0 Mediator complex subunit 30 SlyX PF04102.12 OAG25788.1 - 0.2 12.3 11.9 1.1 10.0 6.1 2.9 2 2 0 2 2 2 0 SlyX GAS PF13851.6 OAG25788.1 - 0.25 10.7 6.1 0.053 12.9 2.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_hydro2_C5 PF18565.1 OAG25789.1 - 2.5e-32 110.8 0.1 4.9e-32 109.8 0.1 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 OAG25789.1 - 2.3e-24 86.0 0.0 4.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 OAG25789.1 - 4.2e-22 77.8 3.7 5.6e-22 77.5 0.8 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 OAG25789.1 - 2.4e-14 53.6 0.1 1.6e-13 50.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OAG25789.1 - 2e-12 47.7 0.1 5.1e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 OAG25789.1 - 9.7e-07 29.0 1.9 2e-06 28.0 0.2 2.2 2 0 0 2 2 2 1 Invasin, domain 3 BetaGal_dom4_5 PF13364.6 OAG25789.1 - 0.001 19.6 0.1 0.13 12.8 0.0 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Big_1 PF02369.16 OAG25789.1 - 0.065 13.3 0.2 0.28 11.2 0.2 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) NAD_binding_11 PF14833.6 OAG25790.1 - 1.7e-37 128.3 0.9 1.3e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAG25790.1 - 2.5e-32 112.2 0.0 4.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG25790.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG25790.1 - 0.014 16.0 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG25790.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pil1 PF13805.6 OAG25791.1 - 3.1e-123 410.5 0.3 4.5e-123 409.9 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Tom37 PF10568.9 OAG25791.1 - 7.2e-34 116.8 0.3 2.3e-33 115.2 0.2 2.0 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 OAG25791.1 - 1.2e-16 60.2 0.0 4.6e-16 58.4 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG25791.1 - 7.6e-06 25.9 0.1 2.2e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG25791.1 - 0.015 16.0 0.0 0.053 14.3 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain FAM92 PF06730.11 OAG25791.1 - 0.19 11.1 2.1 0.24 10.8 1.0 1.6 1 1 1 2 2 2 0 FAM92 protein CDC45 PF02724.14 OAG25792.1 - 0.14 10.5 2.6 0.15 10.4 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.12 OAG25792.1 - 0.34 9.9 1.7 0.55 9.1 1.7 1.4 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Saw1 PF11561.8 OAG25792.1 - 4 6.9 9.4 51 3.3 0.0 2.5 2 1 0 2 2 2 0 Single strand annealing-weakened 1 GFO_IDH_MocA PF01408.22 OAG25794.1 - 2.9e-18 66.8 0.0 5.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_S28 PF05577.12 OAG25795.1 - 2.9e-47 161.5 0.9 1.5e-46 159.1 0.9 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FA_desaturase PF00487.24 OAG25796.1 - 3.1e-13 50.1 23.0 5.6e-13 49.3 23.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF1378 PF07125.11 OAG25796.1 - 0.52 10.5 1.9 1 9.5 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) EzrA PF06160.12 OAG25797.1 - 0.21 9.7 0.1 0.31 9.2 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GRP PF07172.11 OAG25798.1 - 0.0013 19.4 0.0 0.0018 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family SIT PF15330.6 OAG25798.1 - 0.065 13.7 0.1 0.088 13.3 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Pex24p PF06398.11 OAG25798.1 - 0.1 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin AT_hook PF02178.19 OAG25799.1 - 0.15 12.1 2.1 0.35 10.9 2.1 1.7 1 0 0 1 1 1 0 AT hook motif VPS11_C PF12451.8 OAG25799.1 - 8.7 6.7 7.0 3.3 8.0 1.8 3.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FAD_binding_4 PF01565.23 OAG25800.1 - 2.1e-16 59.9 0.0 3.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 OAG25801.1 - 2.3e-18 66.3 0.0 3.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.7 OAG25802.1 - 4.3e-07 30.7 0.0 6.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG25802.1 - 6.4e-05 22.3 0.1 0.00015 21.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG25802.1 - 0.0077 15.9 0.1 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 OAG25802.1 - 0.012 14.9 0.2 0.019 14.3 0.2 1.3 1 0 0 1 1 1 0 Secretory lipase Isochorismatase PF00857.20 OAG25803.1 - 2.4e-13 50.7 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family zf-CRD PF17979.1 OAG25804.1 - 0.34 11.0 5.2 0.26 11.4 3.1 1.8 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF4231 PF14015.6 OAG25805.1 - 0.18 12.3 1.1 0.24 11.9 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Fungal_trans_2 PF11951.8 OAG25806.1 - 5.2e-34 117.7 0.0 7.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG25806.1 - 2e-06 27.8 8.6 3.1e-06 27.2 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUR7 PF06687.12 OAG25807.1 - 3.3e-27 95.5 4.5 4.6e-27 95.1 4.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S4e PF00900.20 OAG25808.1 - 5.6e-38 128.7 0.3 1.2e-37 127.7 0.3 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAG25808.1 - 5.1e-22 77.2 0.1 8.7e-22 76.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAG25808.1 - 1.7e-16 60.0 5.0 3.3e-16 59.1 5.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 OAG25808.1 - 5e-06 26.1 0.0 9.7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OAG25808.1 - 8.4e-05 22.4 3.6 8.4e-05 22.4 3.6 3.2 4 0 0 4 4 4 1 KOW motif Semialdhyde_dhC PF02774.18 OAG25809.1 - 5.7e-41 140.6 0.0 7.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAG25809.1 - 6.3e-30 104.1 0.0 1.5e-29 102.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 OAG25809.1 - 0.037 14.7 0.0 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 OAG25809.1 - 0.052 13.8 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_C PF02800.20 OAG25809.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain FAD-oxidase_C PF02913.19 OAG25810.1 - 4e-65 219.9 0.0 6.9e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG25810.1 - 5.1e-32 110.5 0.0 9.2e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain RdRP PF05183.12 OAG25813.1 - 4.6e-181 603.4 0.0 6.5e-181 602.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 OAG25813.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Flg_new PF09479.10 OAG25813.1 - 0.14 12.4 4.2 39 4.5 0.0 4.2 4 0 0 4 4 4 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) ELP6 PF09807.9 OAG25814.1 - 0.00018 21.1 0.0 0.0055 16.2 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 Totivirus_coat PF05518.11 OAG25814.1 - 1.3 7.0 3.7 1.7 6.6 3.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein F-box-like PF12937.7 OAG25815.1 - 9.4e-06 25.4 0.2 9.4e-06 25.4 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG25815.1 - 1.8e-05 24.4 0.1 4.1e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG25815.1 - 0.0026 17.6 0.3 0.0073 16.2 0.1 1.8 2 0 0 2 2 2 1 F-box FMO-like PF00743.19 OAG25817.1 - 4.3e-12 45.2 0.1 3.4e-11 42.3 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG25817.1 - 5.3e-10 39.0 0.6 3.7e-07 29.6 0.1 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG25817.1 - 2e-09 37.1 0.0 4.6e-06 26.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG25817.1 - 2.2e-09 37.0 0.0 0.00016 21.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG25817.1 - 2.6e-08 34.0 0.0 5.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG25817.1 - 7.7e-07 29.0 0.6 0.012 15.2 0.1 2.7 1 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG25817.1 - 0.00017 20.8 0.0 0.0019 17.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG25817.1 - 0.00018 21.6 0.9 0.5 10.3 0.2 2.8 2 1 1 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 OAG25817.1 - 0.0013 17.9 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAG25817.1 - 0.0049 16.1 0.0 0.072 12.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG25817.1 - 0.02 13.6 0.2 3.8 6.1 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 OAG25817.1 - 0.082 12.0 0.0 0.93 8.5 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 OAG25817.1 - 0.089 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain LigD_N PF13298.6 OAG25818.1 - 5.1e-32 110.3 0.1 6e-31 106.8 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase Ligase (LigD) Lipase_3 PF01764.25 OAG25819.1 - 6.5e-34 116.8 0.0 1.6e-33 115.6 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAG25819.1 - 1.5e-05 24.4 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 OAG25819.1 - 3.5e-05 23.5 0.6 0.00014 21.5 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OAG25819.1 - 0.00017 22.2 0.0 0.0002 22.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase3_N PF03893.16 OAG25819.1 - 0.0022 18.0 0.1 0.0046 17.0 0.1 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF676 PF05057.14 OAG25819.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 OAG25819.1 - 0.0095 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 OAG25819.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG25819.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 OAG25819.1 - 0.027 14.0 0.1 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 OAG25819.1 - 0.041 13.5 0.1 0.072 12.7 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 OAG25819.1 - 0.061 13.4 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Thioesterase domain FtsL PF04999.13 OAG25820.1 - 0.0061 16.5 0.1 0.0085 16.1 0.1 1.2 1 0 0 1 1 1 1 Cell division protein FtsL DUF1204 PF06721.11 OAG25820.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) MARVEL PF01284.23 OAG25821.1 - 0.0012 18.9 12.9 0.0017 18.4 12.5 1.4 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_M20 PF01546.28 OAG25822.1 - 1.1e-20 74.3 0.1 1.8e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG25822.1 - 4.2e-15 55.6 0.2 9.6e-15 54.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Complex1_LYR PF05347.15 OAG25824.1 - 4.5e-19 68.3 4.3 4.9e-19 68.1 3.5 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG25824.1 - 3.6e-06 27.6 1.2 4.1e-06 27.5 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OAG25824.1 - 0.0041 17.7 0.3 0.005 17.4 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Wound_ind PF08186.11 OAG25824.1 - 0.22 12.0 1.2 1.7 9.2 0.4 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family PRP21_like_P PF12230.8 OAG25825.1 - 3.1e-48 164.5 8.0 1.6e-47 162.2 8.0 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAG25825.1 - 3.2e-25 87.9 4.5 6.7e-14 51.6 0.7 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAG25825.1 - 0.00062 19.3 0.5 0.0018 17.9 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 OAG25826.1 - 6.3e-82 274.8 14.4 1.1e-81 274.1 14.4 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG25826.1 - 4.9e-67 225.4 13.7 4.9e-67 225.4 13.7 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG25826.1 - 1.8e-48 164.9 0.5 6.3e-48 163.1 0.0 2.1 2 0 0 2 2 2 1 MIR domain Aldolase_II PF00596.21 OAG25828.1 - 3e-37 128.4 1.0 9.5e-37 126.7 1.0 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RhgB_N PF09284.10 OAG25829.1 - 5.8e-94 314.3 4.2 7.1e-94 314.0 4.2 1.0 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal gag-asp_proteas PF13975.6 OAG25829.1 - 0.015 15.8 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Anticodon_1 PF08264.13 OAG25832.1 - 0.22 11.5 2.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA GAGA_bind PF06217.12 OAG25833.1 - 0.037 14.3 0.4 0.042 14.1 0.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Myb_DNA-bind_4 PF13837.6 OAG25833.1 - 1.2 9.6 4.4 7.4 7.0 4.4 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Atg14 PF10186.9 OAG25833.1 - 2 7.4 8.2 2.6 7.0 8.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 OAG25833.1 - 6.6 7.1 8.3 18 5.7 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Yae1_N PF09811.9 OAG25834.1 - 9.9e-05 22.0 1.4 9.9e-05 22.0 1.4 3.7 2 1 2 4 4 4 2 Essential protein Yae1, N terminal DUF2717 PF10911.8 OAG25834.1 - 0.25 11.1 3.5 22 4.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2717) RE_HindIII PF09518.10 OAG25834.1 - 0.67 9.1 5.9 0.94 8.7 5.9 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease adh_short PF00106.25 OAG25835.1 - 2.1e-30 105.7 0.8 1e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25835.1 - 1.2e-22 80.6 0.4 8.3e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25835.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG25835.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 OAG25835.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DSBA PF01323.20 OAG25836.1 - 1.2e-22 80.6 0.0 1.5e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Arteri_GP4 PF02497.15 OAG25837.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Arterivirus glycoprotein ATP_transf PF09830.9 OAG25838.1 - 3.1e-20 72.1 0.0 5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 OAG25838.1 - 0.0092 16.7 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 OAG25838.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) MFS_1 PF07690.16 OAG25840.1 - 7.6e-33 113.9 23.5 1.1e-32 113.4 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M50 PF02163.22 OAG25840.1 - 0.04 13.2 0.5 0.061 12.6 0.5 1.5 1 1 0 1 1 1 0 Peptidase family M50 DHDPS PF00701.22 OAG25841.1 - 8.8e-37 126.4 0.0 1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 OAG25841.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PA domain Fungal_trans PF04082.18 OAG25842.1 - 1.3e-25 90.0 1.8 3.4e-25 88.6 1.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG25843.1 - 5e-10 39.3 9.6 1.1e-09 38.2 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ntox50 PF15542.6 OAG25844.1 - 0.42 11.5 3.5 1.8 9.4 3.5 2.1 1 0 0 1 1 1 0 Bacterial toxin 50 AMP-binding PF00501.28 OAG25845.1 - 7.3e-61 206.0 0.0 1.1e-60 205.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG25845.1 - 8.7e-13 49.1 0.7 1.6e-12 48.2 0.7 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4362 PF14275.6 OAG25845.1 - 0.086 13.1 0.5 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) XPG_N PF00752.17 OAG25846.1 - 6.3e-35 119.7 0.1 1.9e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 OAG25846.1 - 2.4e-25 88.7 0.8 6.6e-25 87.3 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 OAG25846.1 - 2.1e-05 25.0 0.1 0.00033 21.2 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 OAG25846.1 - 0.001 19.3 0.1 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family UIM PF02809.20 OAG25846.1 - 0.0012 18.6 0.5 0.0012 18.6 0.5 4.0 3 0 0 3 3 3 1 Ubiquitin interaction motif HHH_5 PF14520.6 OAG25846.1 - 0.024 15.3 0.1 0.069 13.8 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain PUB_1 PF18486.1 OAG25846.1 - 0.098 12.5 0.0 0.098 12.5 0.0 2.7 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain HHH PF00633.23 OAG25846.1 - 0.14 12.0 0.1 0.49 10.4 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3336 PF11815.8 OAG25847.1 - 1.4e-47 160.9 2.6 2.1e-47 160.3 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG25847.1 - 1.1e-17 64.9 0.1 7.6e-16 58.9 0.0 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase Peptidase_M22 PF00814.25 OAG25848.1 - 3.7e-37 128.5 0.6 3.3e-25 89.3 0.1 4.0 2 1 0 3 3 3 3 Glycoprotease family DUF1989 PF09347.10 OAG25850.1 - 2.9e-26 92.1 0.0 3.3e-17 62.6 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1989) CDC45 PF02724.14 OAG25850.1 - 0.14 10.4 38.5 0.07 11.4 17.8 2.1 2 0 0 2 2 2 0 CDC45-like protein BTB PF00651.31 OAG25852.1 - 4.9e-07 30.0 0.0 9.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TonB_N PF16031.5 OAG25852.1 - 0.0014 19.2 14.7 0.002 18.7 14.7 1.2 1 0 0 1 1 1 1 TonB polyproline region Trypan_PARP PF05887.11 OAG25852.1 - 0.1 12.6 17.2 0.16 12.0 17.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UBA_4 PF14555.6 OAG25853.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DAHP_synth_2 PF01474.16 OAG25854.1 - 7e-206 683.9 0.0 8.1e-206 683.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF1631 PF07793.11 OAG25855.1 - 4.2 5.7 7.7 4.6 5.5 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SET PF00856.28 OAG25857.1 - 1e-09 39.0 0.4 1e-09 39.0 0.4 3.0 2 2 0 2 2 2 1 SET domain preSET_CXC PF18264.1 OAG25857.1 - 1.1e-08 35.4 12.4 1.1e-08 35.4 12.4 4.0 3 1 1 4 4 4 2 CXC domain Fibritin_C PF07921.12 OAG25857.1 - 0.097 12.8 0.3 17 5.6 0.2 2.6 2 0 0 2 2 2 0 Fibritin C-terminal region ANTH PF07651.16 OAG25858.1 - 1.1e-62 211.6 0.2 1.4e-62 211.2 0.2 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAG25858.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ENTH domain CS PF04969.16 OAG25859.1 - 2.1e-17 63.9 0.1 2.1e-17 63.9 0.1 1.7 3 0 0 3 3 3 1 CS domain PGBA_C PF15437.6 OAG25859.1 - 0.028 14.8 3.0 1.1 9.7 0.3 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Herpes_BTRF1 PF04682.12 OAG25860.1 - 0.0047 16.3 0.8 0.0088 15.4 0.8 1.4 1 0 0 1 1 1 1 Herpesvirus BTRF1 protein conserved region MMM1 PF10296.9 OAG25860.1 - 0.0049 16.0 0.0 0.026 13.6 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 OAG25860.1 - 0.078 13.4 1.5 0.25 11.8 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain MoaE PF02391.17 OAG25861.1 - 1.7e-35 121.7 0.0 2.3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein TMEM126 PF07114.11 OAG25863.1 - 0.063 12.7 0.8 0.11 11.9 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 126 RRM_1 PF00076.22 OAG25864.1 - 1.3e-12 47.4 0.2 5.8e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 OAG25865.1 - 0.0035 17.6 0.2 1.6 9.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat CEP19 PF14933.6 OAG25865.1 - 0.048 14.0 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 CEP19-like protein TPR_10 PF13374.6 OAG25865.1 - 0.26 11.2 0.8 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps62 PF06101.11 OAG25866.1 - 1e-18 67.0 1.9 1.6e-18 66.4 1.9 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Dicty_CAR PF05462.11 OAG25867.1 - 3.5e-07 29.6 6.0 3.5e-07 29.6 6.0 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OAG25867.1 - 1.9e-05 24.5 8.5 3.5e-05 23.7 8.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 OAG25867.1 - 5e-05 22.7 5.0 5e-05 22.7 5.0 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 OAG25867.1 - 0.0082 16.2 0.8 0.027 14.5 0.8 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_M56 PF05569.11 OAG25867.1 - 0.026 13.7 0.3 0.026 13.7 0.3 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 Catalase PF00199.19 OAG25868.1 - 6.6e-23 81.4 0.0 8.8e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Catalase His_Phos_2 PF00328.22 OAG25869.1 - 0.0074 15.7 0.2 0.12 11.6 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Septin PF00735.18 OAG25870.1 - 8.7e-34 117.1 0.0 5.8e-12 45.5 0.0 3.2 3 0 0 3 3 3 3 Septin AAA_16 PF13191.6 OAG25870.1 - 0.0045 17.4 0.0 0.05 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 OAG25870.1 - 0.008 16.2 0.3 0.077 13.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.13 OAG25870.1 - 0.025 13.7 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 OAG25870.1 - 0.028 14.9 0.3 0.15 12.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAG25870.1 - 0.028 14.5 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAG25870.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 OAG25870.1 - 0.046 14.1 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Spem1 PF15670.5 OAG25870.1 - 0.057 13.0 1.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Spermatid maturation protein 1 G-alpha PF00503.20 OAG25870.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 OAG25870.1 - 0.077 12.7 0.1 0.86 9.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 OAG25870.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAG25870.1 - 0.15 11.2 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain adh_short PF00106.25 OAG25871.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG25871.1 - 2.9e-06 27.3 0.0 6.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG25871.1 - 4.4e-06 26.4 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Yae1_N PF09811.9 OAG25872.1 - 1.4e-13 50.2 3.1 2.3e-13 49.6 3.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ABC1 PF03109.16 OAG25873.1 - 4.8e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family ECH_1 PF00378.20 OAG25874.1 - 1.6e-30 106.2 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG25874.1 - 7e-14 52.1 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAA_hydrolase PF01557.18 OAG25875.1 - 5.5e-55 186.4 0.0 6.6e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PQ-loop PF04193.14 OAG25876.1 - 1.8e-33 114.1 10.3 1.1e-16 60.4 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat Polyketide_cyc2 PF10604.9 OAG25877.1 - 3.8e-07 30.5 0.2 2.2e-06 28.0 0.2 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG25877.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.25 OAG25880.1 - 9.8e-33 113.3 0.0 2e-32 112.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25880.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25880.1 - 1.1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG25880.1 - 5.7e-05 22.7 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG25880.1 - 0.00044 19.5 0.0 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG25880.1 - 0.00075 19.0 0.0 0.001 18.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG25880.1 - 0.004 17.1 0.0 0.005 16.7 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG25880.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG25880.1 - 0.022 13.9 0.1 0.035 13.3 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein PALP PF00291.25 OAG25881.1 - 4.8e-78 262.5 0.2 6.3e-78 262.2 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAG25881.1 - 8.1e-44 147.3 0.0 7.9e-21 73.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Metal_CEHH PF14455.6 OAG25883.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted metal binding domain Mito_fiss_reg PF05308.11 OAG25884.1 - 0.13 12.3 2.6 0.17 11.9 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 OAG25884.1 - 2.7 8.0 9.3 4.2 7.4 9.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 OAG25884.1 - 3.8 6.9 9.6 5.4 6.4 9.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SecG PF03840.14 OAG25885.1 - 0.027 14.5 1.8 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Cation_ATPase_C PF00689.21 OAG25886.1 - 6.6e-41 140.0 4.8 6.6e-41 140.0 4.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG25886.1 - 4.4e-39 133.9 0.9 4.4e-39 133.9 0.9 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG25886.1 - 8e-21 75.3 0.2 1.2e-14 55.1 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG25886.1 - 8.3e-19 67.5 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG25886.1 - 2.5e-13 49.5 0.0 6.4e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG25886.1 - 2.8e-05 24.0 0.4 5.6e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 OAG25886.1 - 0.0033 17.2 13.5 0.013 15.3 1.2 4.2 3 2 0 3 3 3 2 Predicted membrane protein (DUF2157) HAD PF12710.7 OAG25886.1 - 0.14 12.6 0.0 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Laminin_G_2 PF02210.24 OAG25886.1 - 0.2 12.2 0.0 0.4 11.3 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF2207 PF09972.9 OAG25886.1 - 0.89 8.2 8.2 12 4.5 0.0 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1996 PF09362.10 OAG25887.1 - 9.1e-71 238.6 0.4 1.2e-70 238.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CDH-cyt PF16010.5 OAG25888.1 - 2.9e-49 167.2 5.4 3.7e-49 166.9 5.4 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAG25888.1 - 0.00026 21.2 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 DOMON domain FAD_binding_3 PF01494.19 OAG25889.1 - 2.5e-26 92.8 0.0 3.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25889.1 - 3.9e-06 26.3 0.0 7.7e-05 22.1 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG25889.1 - 2.1e-05 23.7 0.0 5.3e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 OAG25889.1 - 0.0002 21.9 0.0 0.012 16.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG25889.1 - 0.00056 20.1 0.2 0.0014 18.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG25889.1 - 0.0042 16.7 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG25889.1 - 0.008 14.9 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG25889.1 - 0.0089 15.2 0.1 0.017 14.2 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAG25889.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG25889.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAG25889.1 - 0.18 11.1 1.9 0.36 10.1 1.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_M24 PF00557.24 OAG25890.1 - 3.2e-45 154.4 0.1 4.1e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OAG25890.1 - 7.3e-19 67.8 10.6 1.6e-18 66.7 10.6 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OAG25890.1 - 0.0008 19.4 9.2 0.0008 19.4 9.2 2.3 2 0 0 2 2 2 1 MYND finger DUF2116 PF09889.9 OAG25890.1 - 0.0064 16.5 2.4 0.014 15.4 2.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Nore1-SARAH PF16517.5 OAG25890.1 - 0.19 11.7 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf-HIT PF04438.16 OAG25890.1 - 0.56 10.1 5.9 1.7 8.6 5.9 1.9 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.14 OAG25891.1 - 1e-50 171.1 12.8 1.2e-50 170.9 12.8 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 OAG25892.1 - 6.9e-28 96.3 4.2 1.1e-07 32.4 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG25892.1 - 1.5e-12 47.6 0.0 0.021 15.1 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG25892.1 - 0.16 11.0 0.1 1.4 7.9 0.0 2.4 2 1 0 2 2 2 0 Coatomer WD associated region PIRT PF15099.6 OAG25893.1 - 0.065 12.8 0.4 0.07 12.7 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Chromate_transp PF02417.15 OAG25894.1 - 4.7e-62 208.8 36.6 5.2e-34 117.7 16.1 2.4 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.14 OAG25894.1 - 3.5 6.9 4.1 1.8 7.9 0.1 2.5 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DJ-1_PfpI PF01965.24 OAG25895.1 - 1.5e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG25895.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like ATP-synt_DE_N PF02823.16 OAG25895.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PIG-S PF10510.9 OAG25896.1 - 7.3e-176 586.0 5.5 8.4e-176 585.8 5.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein SMBP PF16785.5 OAG25896.1 - 0.073 13.3 0.1 0.073 13.3 0.1 2.8 3 0 0 3 3 3 0 Small metal-binding protein Beta-lactamase PF00144.24 OAG25897.1 - 2.3e-41 142.1 0.1 7.3e-41 140.5 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase Chlorophyllase2 PF12740.7 OAG25899.1 - 2.3e-05 23.5 0.0 3.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 OAG25899.1 - 0.052 13.2 0.1 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 OAG25899.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 OAG25899.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1932 PF09130.11 OAG25900.1 - 4.4e-20 71.4 0.0 1.2e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 OAG25900.1 - 5.3e-08 33.2 0.0 1.7e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG25900.1 - 4.1e-06 27.3 0.0 7.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG25900.1 - 0.00022 20.7 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OAG25900.1 - 0.0012 18.7 0.1 0.0037 17.1 0.1 1.8 1 1 0 1 1 1 1 Rossmann-like domain PDH PF02153.17 OAG25900.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase AlaDh_PNT_N PF05222.15 OAG25900.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Nuc_deoxyrib_tr PF05014.15 OAG25900.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase 3HCDH_N PF02737.18 OAG25900.1 - 0.17 11.7 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PIP5K PF01504.18 OAG25901.1 - 1.4e-38 132.7 3.5 4.1e-31 108.2 0.9 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAG25901.1 - 1.6e-30 106.2 0.0 2.8e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAG25901.1 - 1.1e-13 51.1 6.9 1.1e-13 51.1 6.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 OAG25901.1 - 0.044 13.7 3.8 0.13 12.2 3.8 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.9 OAG25902.1 - 0.037 14.0 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Med10 PF09748.9 OAG25902.1 - 0.1 12.6 0.2 0.3 11.0 0.2 1.8 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex p450 PF00067.22 OAG25903.1 - 1.5e-50 172.3 0.0 2.2e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG25903.1 - 1.7e-16 60.1 43.1 1.2e-10 40.9 8.8 3.7 4 0 0 4 4 4 3 Major Facilitator Superfamily ATG22 PF11700.8 OAG25903.1 - 8e-06 24.7 1.2 0.00011 21.0 0.0 2.6 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like TNFR_16_TM PF18422.1 OAG25903.1 - 0.066 13.2 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain SNN_transmemb PF09049.10 OAG25903.1 - 8.6 6.4 9.2 6.7 6.7 1.0 3.7 3 0 0 3 3 3 0 Stannin transmembrane Acetyltransf_7 PF13508.7 OAG25904.1 - 1.7e-08 34.8 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG25904.1 - 1.9e-08 34.3 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG25904.1 - 1.5e-07 31.7 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG25904.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG25904.1 - 0.00034 20.7 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 OAG25904.1 - 0.0021 17.5 0.0 0.0059 16.0 0.0 1.6 1 1 1 2 2 2 1 GNAT acetyltransferase 2 Acetyltransf_CG PF14542.6 OAG25904.1 - 0.015 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 OAG25904.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_3 PF13302.7 OAG25904.1 - 0.072 13.8 0.0 0.091 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.7 OAG25905.1 - 4.2e-07 29.8 0.5 9.3e-07 28.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAG25905.1 - 3.7e-06 26.8 0.3 8.8e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 OAG25905.1 - 0.0012 18.7 0.1 0.0028 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Ribosomal_L37e PF01907.19 OAG25906.1 - 1.9e-27 95.2 11.5 2.9e-27 94.6 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 OAG25906.1 - 0.0029 17.6 2.1 0.0046 17.0 2.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C4pol PF14260.6 OAG25906.1 - 0.012 16.1 0.7 0.018 15.5 0.7 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-ribbon_3 PF13248.6 OAG25906.1 - 0.041 13.3 1.1 0.079 12.4 1.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 OAG25906.1 - 0.086 12.9 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 OAG25906.1 - 0.21 11.5 3.2 0.38 10.7 3.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2688 PF10892.8 OAG25906.1 - 0.94 9.0 4.6 6.5 6.3 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Sugar_tr PF00083.24 OAG25907.1 - 7.5e-41 140.4 22.0 9e-41 140.2 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG25907.1 - 3.3e-18 65.7 26.8 5.7e-18 65.0 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BPL_LplA_LipB PF03099.19 OAG25908.1 - 5.5e-11 42.5 0.0 7.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.8 OAG25909.1 - 7.8e-32 110.1 0.2 3.6e-31 108.0 0.2 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 OAG25909.1 - 3.4e-08 33.2 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Alba FHA PF00498.26 OAG25911.1 - 4.6e-16 58.9 0.1 1.2e-15 57.6 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG25911.1 - 0.00072 19.8 0.0 0.0023 18.2 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 OAG25911.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 YhfZ C-terminal domain Hormone_1 PF00103.20 OAG25911.1 - 0.45 10.2 6.0 0.09 12.5 2.3 1.7 2 0 0 2 2 2 0 Somatotropin hormone family CEP63 PF17045.5 OAG25911.1 - 1.9 8.3 24.7 0.066 13.1 6.6 3.1 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Romo1 PF10247.9 OAG25912.1 - 3e-26 91.6 13.9 3.7e-26 91.3 13.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 OAG25912.1 - 0.0082 16.5 2.7 0.0096 16.3 2.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Form-deh_trans PF09163.11 OAG25912.1 - 2.2 8.1 6.0 6.9 6.5 0.4 2.3 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane HEAT_2 PF13646.6 OAG25913.1 - 0.016 15.5 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats ZapB PF06005.12 OAG25913.1 - 0.24 11.9 20.4 2.1 8.8 1.4 3.8 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_2 PF07716.15 OAG25913.1 - 0.27 11.3 18.5 0.3 11.2 3.9 4.1 4 0 0 4 4 4 0 Basic region leucine zipper APG6_N PF17675.1 OAG25913.1 - 0.4 11.2 20.8 1.3e+02 3.0 19.5 2.7 1 1 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 OAG25913.1 - 1.1 9.4 11.2 1.3 9.2 0.1 3.6 3 1 1 4 4 4 0 bZIP transcription factor TSC22 PF01166.18 OAG25913.1 - 8.6 6.8 11.9 2.3 8.6 1.4 3.5 2 1 2 4 4 4 0 TSC-22/dip/bun family NqrM PF04400.13 OAG25914.1 - 0.092 12.5 0.7 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM FKBP_C PF00254.28 OAG25915.1 - 4.2e-31 107.1 0.0 5.2e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAD_binding_4 PF01565.23 OAG25916.1 - 1.6e-19 70.0 0.8 2.7e-19 69.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG25916.1 - 6.3e-11 42.2 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like zf-C3HC4_3 PF13920.6 OAG25920.1 - 0.061 13.2 3.5 0.093 12.6 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OAG25920.1 - 0.25 11.5 4.7 0.5 10.6 4.7 1.4 1 0 0 1 1 1 0 B-box zinc finger SIR2 PF02146.17 OAG25921.1 - 1.4e-31 109.8 0.0 2.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Myb_DNA-binding PF00249.31 OAG25922.1 - 1.4e-07 31.5 0.3 7.1e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG25922.1 - 6.5e-07 29.5 0.5 5.4e-05 23.4 0.1 2.4 1 1 1 2 2 2 1 Myb-like DNA-binding domain FAM70 PF14967.6 OAG25922.1 - 2.4 7.6 6.2 3.2 7.1 6.2 1.2 1 0 0 1 1 1 0 FAM70 protein Minor_tail_Z PF06763.11 OAG25922.1 - 5.7 6.7 8.6 3.7 7.3 6.1 2.0 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Zf_RING PF16744.5 OAG25923.1 - 0.065 13.3 0.7 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Glyco_hydro_3_C PF01915.22 OAG25924.1 - 8.3e-47 159.8 0.0 2.4e-46 158.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG25924.1 - 1.8e-42 145.9 0.0 2.8e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG25924.1 - 1.6e-23 82.6 0.4 3.5e-23 81.5 0.3 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain GTP_EFTU PF00009.27 OAG25926.1 - 2.8e-59 199.9 0.1 5.6e-59 198.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAG25926.1 - 1.2e-34 118.7 0.1 2.4e-34 117.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 OAG25926.1 - 3.4e-33 113.6 0.1 7.7e-33 112.4 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAG25926.1 - 1.3e-23 82.8 0.0 7.4e-23 80.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG25926.1 - 4.3e-14 52.7 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAG25926.1 - 4e-07 29.9 0.1 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OAG25926.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Val_tRNA-synt_C PF10458.9 OAG25926.1 - 0.21 11.9 1.1 0.32 11.3 0.1 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Hydrolase_4 PF12146.8 OAG25927.1 - 1.7e-07 30.8 0.0 2.4e-06 27.0 0.0 2.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG25927.1 - 0.00032 21.4 0.0 0.00052 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG25927.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SKG6 PF08693.10 OAG25929.1 - 6.8e-07 28.6 0.1 1.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TrbL PF04610.14 OAG25929.1 - 0.17 11.6 1.2 0.26 11.0 1.2 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Glyco_hydro_61 PF03443.14 OAG25930.1 - 0.015 15.2 0.2 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Xpo1 PF08389.12 OAG25932.1 - 9.5e-34 116.6 7.0 2.3e-32 112.1 0.1 4.8 4 1 0 4 4 4 1 Exportin 1-like protein DRIM PF07539.12 OAG25932.1 - 8.8e-05 21.0 1.3 0.016 13.6 0.1 2.9 2 1 0 2 2 2 2 Down-regulated in metastasis HEAT PF02985.22 OAG25932.1 - 0.078 13.3 0.0 86 3.8 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Esterase PF00756.20 OAG25933.1 - 1.3e-54 185.5 0.1 1.6e-54 185.2 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAG25933.1 - 2.7e-06 27.0 0.1 4.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAG25933.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG25933.1 - 0.0044 16.3 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 OAG25933.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 OAG25933.1 - 0.01 15.3 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase PGAP1 PF07819.13 OAG25933.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 OAG25933.1 - 0.04 13.4 0.1 0.097 12.2 0.1 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 OAG25933.1 - 0.041 12.9 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase RNA_pol_Rpb6 PF01192.22 OAG25934.1 - 1.6e-15 56.7 0.7 2.7e-15 56.0 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 DUF4549 PF15082.6 OAG25934.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) KH_1 PF00013.29 OAG25934.1 - 0.19 11.6 0.1 0.84 9.5 0.1 2.0 2 0 0 2 2 2 0 KH domain zf-C2H2 PF00096.26 OAG25935.1 - 3.4e-34 115.4 51.1 1.4e-05 25.2 0.9 10.5 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25935.1 - 3.8e-23 80.2 48.7 0.0044 17.7 2.5 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG25935.1 - 3.1e-11 43.1 51.5 0.00037 20.8 1.0 11.4 11 0 0 11 11 11 3 Zinc-finger double domain zf-met PF12874.7 OAG25935.1 - 5.3e-09 36.2 14.9 0.35 11.3 0.5 8.4 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OAG25935.1 - 1.4e-05 25.7 25.2 0.056 14.1 3.3 5.6 2 1 3 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 OAG25935.1 - 0.00039 20.7 20.9 0.0074 16.6 2.3 5.2 3 2 3 6 6 6 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OAG25935.1 - 0.00077 19.4 29.3 0.024 14.6 0.8 7.7 8 0 0 8 8 8 3 C2H2-type zinc finger FOXP-CC PF16159.5 OAG25935.1 - 0.0011 19.6 40.9 0.078 13.6 0.4 8.4 6 2 3 9 9 8 2 FOXP coiled-coil domain zf_UBZ PF18439.1 OAG25935.1 - 0.085 12.5 9.6 7.1 6.3 0.0 5.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 OAG25935.1 - 0.096 12.5 0.1 0.096 12.5 0.1 5.8 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 OAG25935.1 - 0.11 12.4 9.3 1.1 9.2 0.3 5.0 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-AD PF07776.15 OAG25935.1 - 0.18 12.1 2.7 0.76 10.1 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.8 OAG25935.1 - 0.79 10.1 40.3 0.84 10.0 0.7 9.6 11 1 0 11 11 10 0 Zinc-finger double-stranded RNA-binding ROS_MUCR PF05443.11 OAG25935.1 - 0.79 9.8 2.9 12 5.9 0.0 4.0 5 1 0 5 5 5 0 ROS/MUCR transcriptional regulator protein zf-C2H2_aberr PF17017.5 OAG25935.1 - 1.3 9.1 15.9 6.7 6.8 0.2 5.2 3 2 3 6 6 6 0 Aberrant zinc-finger SNARE PF05739.19 OAG25937.1 - 2.3e-11 43.5 0.1 2.3e-11 43.5 0.1 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin-5_N PF11416.8 OAG25937.1 - 7.8e-09 34.5 1.5 3.8e-08 32.3 1.5 2.3 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 OAG25937.1 - 4.8e-05 23.1 14.8 0.00015 21.5 0.3 3.3 2 1 1 3 3 3 2 Syntaxin Surfac_D-trimer PF09006.11 OAG25937.1 - 0.015 15.1 0.6 0.16 11.9 0.2 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF16 PF01519.16 OAG25937.1 - 0.017 15.6 0.7 0.017 15.6 0.7 2.9 2 1 0 2 2 1 0 Protein of unknown function DUF16 Syntaxin-18_N PF10496.9 OAG25937.1 - 0.017 15.3 1.1 0.017 15.3 1.1 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 OAG25937.1 - 0.073 13.4 7.3 3.4 8.0 0.1 3.6 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 OAG25937.1 - 0.17 12.5 0.3 0.17 12.5 0.3 3.8 3 1 0 3 3 3 0 SlyX DUF1664 PF07889.12 OAG25937.1 - 0.53 10.3 5.8 1.4 8.9 0.2 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OAG25937.1 - 0.71 10.2 3.6 2.4 8.5 0.0 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 OAG25937.1 - 1.3 9.5 6.7 5.8 7.4 0.8 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RcsF PF16358.5 OAG25937.1 - 3.4 7.8 5.8 0.38 10.8 0.3 2.1 2 0 0 2 2 2 0 RcsF lipoprotein PSCyt3 PF07627.11 OAG25938.1 - 1.2 9.4 4.6 0.91 9.8 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Baculo_19 PF04798.12 OAG25939.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Mannosyl_trans PF05007.13 OAG25940.1 - 1.8e-77 260.7 11.4 1.8e-77 260.7 11.4 1.5 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OAG25940.1 - 2.4e-15 56.5 2.8 2.4e-15 56.5 2.8 1.7 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Translin PF01997.16 OAG25941.1 - 1.1e-68 231.3 0.0 1.3e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Translin family PIN_4 PF13638.6 OAG25942.1 - 0.00022 21.5 0.0 0.0077 16.5 0.0 2.3 2 0 0 2 2 2 1 PIN domain DUF3275 PF11679.8 OAG25942.1 - 4.8 7.1 7.4 2.2 8.2 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) ABC_membrane PF00664.23 OAG25943.1 - 1.2e-89 300.7 30.7 7.7e-46 156.9 13.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG25943.1 - 1.2e-55 187.7 0.0 8.3e-27 94.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG25943.1 - 3.1e-09 36.6 8.4 0.00012 21.6 0.0 5.0 3 2 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG25943.1 - 3.9e-08 32.9 1.7 0.0067 16.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG25943.1 - 9.1e-08 32.5 2.1 0.02 15.2 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG25943.1 - 1.1e-07 32.0 0.1 0.44 10.3 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OAG25943.1 - 4.4e-07 29.0 0.6 0.15 10.8 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OAG25943.1 - 1.1e-06 29.1 0.1 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG25943.1 - 1.9e-06 27.9 0.1 0.067 13.1 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAG25943.1 - 4.1e-06 26.7 0.0 0.096 12.4 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.17 OAG25943.1 - 6.2e-05 22.8 0.1 5.7 6.6 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAG25943.1 - 6.4e-05 22.6 0.2 0.34 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAG25943.1 - 0.00033 21.2 0.0 1.9 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAG25943.1 - 0.00091 19.4 0.5 1.9 8.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAG25943.1 - 0.0036 17.3 0.8 5.8 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAG25943.1 - 0.0051 17.3 0.7 0.66 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG25943.1 - 0.0074 16.0 0.7 1.8 8.3 0.1 3.2 2 2 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAG25943.1 - 0.016 15.1 0.5 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 OAG25943.1 - 0.021 14.9 6.6 0.12 12.4 0.9 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 OAG25943.1 - 0.03 14.0 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 OAG25943.1 - 0.031 14.4 0.3 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.23 OAG25943.1 - 0.032 14.3 0.4 0.96 9.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 OAG25943.1 - 0.035 13.8 0.1 4.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_24 PF13479.6 OAG25943.1 - 0.037 13.8 0.2 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAG25943.1 - 0.039 13.3 2.3 2 7.7 0.0 3.1 3 0 0 3 3 3 0 KaiC Ploopntkinase3 PF18751.1 OAG25943.1 - 0.046 13.6 0.1 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 OAG25943.1 - 0.048 14.1 0.1 20 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OAG25943.1 - 0.067 12.7 0.0 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ESSS PF10183.9 OAG25943.1 - 0.08 13.2 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PRK PF00485.18 OAG25943.1 - 0.094 12.4 0.5 0.86 9.3 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 OAG25943.1 - 0.12 12.1 0.2 18 5.0 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Erp_C PF06780.11 OAG25943.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Erp protein C-terminus DUF5345 PF17280.2 OAG25943.1 - 0.16 11.9 3.2 0.11 12.5 0.2 2.4 2 0 0 2 2 1 0 Family of unknown function (DUF5345) DUF3987 PF13148.6 OAG25943.1 - 0.18 10.8 0.0 4.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.20 OAG25943.1 - 0.18 11.0 0.1 17 4.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 OAG25943.1 - 0.19 11.7 0.5 18 5.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Polysacc_synt_4 PF04669.13 OAG25944.1 - 1.2e-23 83.6 1.2 5.6e-22 78.2 1.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis PQQ_2 PF13360.6 OAG25944.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain DUF512 PF04459.12 OAG25944.1 - 0.018 14.3 0.2 0.019 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) WD40 PF00400.32 OAG25945.1 - 3.7e-13 49.7 27.5 0.00063 20.5 0.0 10.5 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG25945.1 - 3.5e-05 24.0 0.0 5.6 7.3 0.0 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 OAG25945.1 - 0.0021 18.1 0.0 0.4 10.8 0.0 3.2 3 0 0 3 3 3 1 YmzC-like protein BRCT_2 PF16589.5 OAG25946.1 - 7e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG25946.1 - 1.4e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Phage_tail_APC PF16778.5 OAG25946.1 - 0.21 11.5 2.4 38 4.3 0.2 3.9 3 1 1 4 4 4 0 Phage tail assembly chaperone protein Cellulase PF00150.18 OAG25949.1 - 6.8e-12 45.4 4.6 2.9e-11 43.3 4.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MutL PF13941.6 OAG25949.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Memo PF01875.17 OAG25950.1 - 5.8e-36 124.0 0.0 6.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein zf-B_box PF00643.24 OAG25951.1 - 0.24 11.6 10.8 0.77 10.0 5.9 2.5 2 1 0 2 2 2 0 B-box zinc finger Fer2_3 PF13085.6 OAG25951.1 - 0.3 11.1 4.6 0.57 10.2 4.6 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain C6_DPF PF10170.9 OAG25951.1 - 0.52 10.7 4.7 0.99 9.8 4.7 1.4 1 0 0 1 1 1 0 Cysteine-rich domain DctP PF03480.13 OAG25952.1 - 0.047 13.0 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Lipoprotein_2 PF00921.17 OAG25952.1 - 0.047 13.2 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein End3 PF12761.7 OAG25952.1 - 0.055 13.6 0.2 0.062 13.5 0.2 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Ribosomal_L20 PF00453.18 OAG25952.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2524 PF10732.9 OAG25952.1 - 0.15 12.4 2.1 0.31 11.3 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) Hamartin PF04388.12 OAG25952.1 - 0.62 8.7 4.2 0.67 8.5 4.2 1.0 1 0 0 1 1 1 0 Hamartin protein AAA PF00004.29 OAG25953.1 - 3.1e-17 63.2 0.0 7.8e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG25953.1 - 0.17 12.3 0.0 8.8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Gpr1_Fun34_YaaH PF01184.19 OAG25954.1 - 3.4e-87 291.4 19.8 4e-87 291.2 19.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PRP38 PF03371.15 OAG25955.1 - 1.8e-64 216.8 0.0 2.2e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 OAG25955.1 - 0.019 15.5 41.4 0.019 15.5 41.4 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Parvo_coat_N PF08398.10 OAG25955.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Parvovirus coat protein VP1 Pkinase PF00069.25 OAG25958.1 - 1e-73 248.0 0.0 1.3e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG25958.1 - 5.1e-38 130.8 0.0 7.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG25958.1 - 4.7e-06 26.1 0.0 8.3e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 OAG25958.1 - 0.11 11.7 0.3 0.33 10.3 0.3 1.7 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Mucin PF01456.17 OAG25958.1 - 0.25 11.3 10.6 0.47 10.4 10.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein HlyIII PF03006.20 OAG25959.1 - 3.1e-47 161.2 8.5 4e-47 160.8 8.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 OAG25959.1 - 0.00099 19.1 0.6 0.00099 19.1 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF962) MFS_1 PF07690.16 OAG25960.1 - 3.5e-29 101.9 48.4 1.3e-25 90.1 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Clr5 PF14420.6 OAG25961.1 - 1.5e-13 50.7 1.7 3.4e-13 49.6 1.7 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_4 PF13637.6 OAG25961.1 - 2.6e-08 34.3 0.0 0.006 17.1 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG25961.1 - 4.2e-08 32.8 0.1 10 7.1 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 OAG25961.1 - 8.4e-07 29.5 0.0 0.00011 22.7 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG25961.1 - 0.018 15.5 2.2 1.2e+02 3.4 0.1 5.3 5 0 0 5 5 5 0 Ankyrin repeat CRAL_TRIO_2 PF13716.6 OAG25961.1 - 0.027 14.6 0.6 1.4 9.1 0.3 2.4 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain Ank_5 PF13857.6 OAG25961.1 - 0.04 14.3 0.0 4.5 7.7 0.0 3.7 4 1 0 4 4 4 0 Ankyrin repeats (many copies) UCH PF00443.29 OAG25963.1 - 2.7e-62 210.6 0.0 4.4e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAG25963.1 - 1.2e-11 45.0 0.1 4.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OAG25963.1 - 4.9e-07 29.6 0.0 0.027 14.1 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 OAG25963.1 - 0.024 14.6 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Lipase_GDSL_2 PF13472.6 OAG25964.1 - 3.1e-26 92.9 0.0 6.5e-26 91.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG25964.1 - 2.4e-20 73.4 0.0 2.9e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.20 OAG25965.1 - 3.6e-87 292.9 22.2 3.6e-87 292.9 22.2 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel PTR2 PF00854.21 OAG25966.1 - 2.9e-59 200.9 8.0 4.1e-59 200.4 8.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG25966.1 - 4.6e-14 52.1 14.4 2.2e-07 30.2 1.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG25966.1 - 0.00095 18.1 2.0 0.032 13.1 0.2 2.6 2 1 0 2 2 2 2 MFS_1 like family DUF2070 PF09843.9 OAG25966.1 - 0.0064 14.8 0.7 0.0064 14.8 0.7 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) TMEM107 PF14995.6 OAG25966.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.9 4 1 1 5 5 5 0 Transmembrane protein Glyco_hydro_61 PF03443.14 OAG25968.1 - 1.3e-55 188.5 0.6 1.9e-55 188.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG25968.1 - 4.6e-10 39.3 5.0 4.6e-10 39.3 5.0 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain zf-C2H2 PF00096.26 OAG25969.1 - 6.3e-09 35.8 15.9 0.014 15.8 2.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG25969.1 - 2.6e-05 24.7 14.3 0.044 14.6 1.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG25969.1 - 5.1e-05 22.9 6.9 0.046 13.5 0.2 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 OAG25969.1 - 9.1e-05 22.7 3.7 0.095 13.1 1.0 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.12 OAG25969.1 - 0.00083 19.5 3.1 0.011 15.9 3.5 2.3 1 1 1 2 2 2 1 TFIIH C1-like domain zf-H2C2_5 PF13909.6 OAG25969.1 - 0.014 15.2 0.6 0.014 15.2 0.6 3.8 3 1 0 3 3 2 0 C2H2-type zinc-finger domain PHD PF00628.29 OAG25969.1 - 0.03 14.2 3.1 0.079 12.9 3.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.8 OAG25969.1 - 0.084 13.2 11.9 0.33 11.3 0.4 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.6 OAG25969.1 - 0.12 12.2 1.6 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.22 OAG25969.1 - 0.34 10.8 3.9 3.4 7.6 0.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 OAG25969.1 - 0.37 10.8 3.3 1.8 8.6 3.6 1.9 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 OAG25969.1 - 0.85 9.6 3.7 6.7 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 OAG25969.1 - 1.7 8.7 9.0 0.056 13.5 2.4 1.9 1 1 1 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAG25969.1 - 3.3 7.9 6.1 21 5.3 0.7 2.5 1 1 1 2 2 2 0 Zinc ribbon domain AATase PF07247.12 OAG25970.1 - 7.5e-23 80.8 0.0 2e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 OAG25970.1 - 0.016 13.9 0.0 0.035 12.8 0.0 1.5 2 0 0 2 2 2 0 Condensation domain His_Phos_2 PF00328.22 OAG25971.1 - 1.8e-24 86.8 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fungal_trans_2 PF11951.8 OAG25972.1 - 1.1e-35 123.2 0.1 1.6e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG25972.1 - 3.4e-07 30.3 11.4 9.4e-07 28.9 11.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG25973.1 - 1.8e-34 118.9 0.0 3.1e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG25973.1 - 1.3e-25 90.4 0.8 7.6e-25 87.8 0.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG25973.1 - 9.9e-12 45.1 2.6 6.8e-11 42.4 0.3 2.7 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 OAG25973.1 - 0.003 17.0 0.1 0.0056 16.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG25973.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.19 OAG25974.1 - 2.9e-12 46.5 0.6 3e-11 43.2 0.5 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG25974.1 - 8.8e-10 38.3 0.0 9e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG25974.1 - 3e-08 33.6 0.9 4.9e-05 23.1 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG25974.1 - 1.4e-07 31.0 0.2 2.9e-07 29.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG25974.1 - 4e-07 29.7 0.1 9.3e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG25974.1 - 8e-06 24.8 0.2 0.00035 19.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG25974.1 - 1.8e-05 24.9 0.7 0.00015 22.0 0.2 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG25974.1 - 0.00034 19.8 0.3 0.007 15.5 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG25974.1 - 0.00045 19.6 0.3 0.0041 16.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG25974.1 - 0.0025 18.4 0.7 0.065 13.8 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG25974.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAG25974.1 - 0.013 14.6 0.1 0.21 10.6 0.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG25974.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OAG25975.1 - 2.4e-07 30.4 1.1 0.00016 21.0 0.6 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG25975.1 - 0.00071 18.9 0.9 0.61 9.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 OAG25976.1 - 4e-13 49.4 0.0 8.4e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG25976.1 - 2e-07 31.1 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG25976.1 - 0.0025 17.4 0.0 0.0071 15.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 OAG25976.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG25976.1 - 0.016 14.7 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG25976.1 - 0.055 12.9 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Ferric_reduct PF01794.19 OAG25977.1 - 1.7e-21 76.6 15.4 1.7e-21 76.6 15.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG25977.1 - 4.8e-15 56.0 0.0 2.2e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG25977.1 - 7.9e-09 35.6 0.0 6.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 OAG25977.1 - 0.009 16.6 0.0 0.045 14.4 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DELLA PF12041.8 OAG25978.1 - 0.1 12.5 0.1 0.63 10.0 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal p450 PF00067.22 OAG25979.1 - 4.4e-43 147.7 0.0 6.4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG25980.1 - 1.1e-16 61.0 0.8 1.7e-15 57.1 0.8 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG25980.1 - 0.0035 17.5 0.2 0.017 15.3 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DUF1737 PF08410.10 OAG25980.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Zn_clus PF00172.18 OAG25981.1 - 8.1e-11 41.9 11.5 1.4e-10 41.1 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG25983.1 - 2e-32 112.5 31.8 2e-32 112.5 31.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 OAG25983.1 - 0.66 10.1 9.5 22 5.1 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function Glyco_hydro_31 PF01055.26 OAG25984.1 - 8.6e-94 315.2 0.1 1.1e-93 314.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG25984.1 - 1.2e-11 44.8 0.0 4.5e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Tyrosinase PF00264.20 OAG25985.1 - 2.1e-49 168.8 1.2 2.9e-49 168.4 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BNR PF02012.20 OAG25986.1 - 1.8 8.9 16.0 0.41 10.8 0.7 4.1 4 0 0 4 4 4 0 BNR/Asp-box repeat Solute_trans_a PF03619.16 OAG25988.1 - 2.7e-74 250.0 25.4 3.6e-74 249.6 25.4 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7tm_1 PF00001.21 OAG25988.1 - 1.2 8.4 13.7 2.9 7.2 4.3 3.1 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) Mem_trans PF03547.18 OAG25989.1 - 3e-16 58.8 8.9 1.1e-15 56.9 8.9 1.7 1 1 0 1 1 1 1 Membrane transport protein SpoIIM PF01944.17 OAG25989.1 - 0.003 17.6 0.2 0.003 17.6 0.2 2.5 3 1 0 3 3 3 1 Stage II sporulation protein M ABC2_membrane PF01061.24 OAG25990.1 - 5e-78 261.3 49.9 7.6e-43 146.4 18.3 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAG25990.1 - 1.3e-33 116.4 0.0 6.8e-19 68.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG25990.1 - 4.9e-25 87.3 9.5 5.5e-24 83.9 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 OAG25990.1 - 1.2e-14 54.2 20.6 3.5e-10 39.5 7.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 OAG25990.1 - 5e-10 39.9 0.1 1.3e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG25990.1 - 9.4e-05 22.9 0.1 0.02 15.3 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG25990.1 - 0.00011 22.2 0.1 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAG25990.1 - 0.0022 17.6 0.1 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG25990.1 - 0.0064 16.8 0.2 0.58 10.4 0.3 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG25990.1 - 0.0093 15.7 0.7 0.077 12.7 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG25990.1 - 0.028 14.3 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 OAG25990.1 - 0.028 14.7 0.7 1.1 9.5 0.4 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG25990.1 - 0.032 13.8 0.3 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OAG25990.1 - 0.034 14.7 0.0 3.4 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAG25990.1 - 0.1 12.3 0.2 8.7 6.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 OAG25990.1 - 0.15 11.3 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 OAG25990.1 - 0.19 11.8 0.2 27 4.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 OAG25990.1 - 0.21 11.8 0.7 7.7 6.8 0.0 3.0 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Shikimate_DH PF01488.20 OAG25991.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MLANA PF14991.6 OAG25992.1 - 0.086 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A Zn_clus PF00172.18 OAG25993.1 - 1.5e-07 31.4 8.8 2.6e-07 30.7 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4360 PF14273.6 OAG25994.1 - 6.4e-19 68.5 4.3 1e-18 67.8 4.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Cofilin_ADF PF00241.20 OAG25995.1 - 3.2e-12 46.3 0.0 2.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RPN7 PF10602.9 OAG25995.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SET PF00856.28 OAG25996.1 - 1e-11 45.5 2.4 4e-09 37.1 0.0 3.5 3 1 0 3 3 3 2 SET domain HypA PF01155.19 OAG25996.1 - 0.25 11.4 1.4 0.43 10.6 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L14 PF00238.19 OAG25997.1 - 1.3e-48 164.1 3.2 1.4e-48 163.9 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 OAG25997.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q RNA_POL_M_15KD PF02150.16 OAG25999.1 - 1.3e-10 41.0 2.8 1.3e-10 41.0 2.8 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit FYVE PF01363.21 OAG25999.1 - 0.056 13.6 4.9 3.1 8.0 0.8 2.3 2 0 0 2 2 2 0 FYVE zinc finger Nudix_N_2 PF14803.6 OAG25999.1 - 0.2 11.6 9.2 0.39 10.7 0.4 3.2 2 1 1 3 3 3 0 Nudix N-terminal CTU2 PF10288.9 OAG25999.1 - 0.7 10.1 4.5 1.3 9.3 4.5 1.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 WW PF00397.26 OAG26000.1 - 8.7e-09 35.3 1.4 1.7e-08 34.4 1.4 1.5 1 0 0 1 1 1 1 WW domain Rotamase PF00639.21 OAG26000.1 - 1e-05 26.4 0.1 1.7e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Sec62 PF03839.16 OAG26002.1 - 5.3 6.5 5.9 8.4 5.8 5.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 OAG26002.1 - 5.4 5.2 6.7 8.1 4.6 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PH PF00169.29 OAG26003.1 - 1.7e-08 34.9 0.0 5.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 OAG26003.1 - 1.9e-05 25.2 0.0 5.8e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH_11 PF15413.6 OAG26003.1 - 0.026 14.9 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain DEAD PF00270.29 OAG26004.1 - 5.1e-29 101.3 0.2 1e-28 100.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG26004.1 - 8.3e-20 71.2 0.0 2.6e-18 66.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG26004.1 - 0.00025 21.1 0.1 0.0019 18.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit OFCC1 PF15680.5 OAG26004.1 - 0.013 16.1 0.9 0.038 14.6 0.9 1.7 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein DUF2428 PF10350.9 OAG26006.1 - 3.2e-67 226.7 0.0 6.3e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 OAG26006.1 - 4.9e-06 26.4 10.0 7.7 7.1 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 OAG26006.1 - 1.2e-05 25.6 4.4 0.68 10.4 0.0 6.4 6 2 0 6 6 6 3 HEAT repeats MBOAT PF03062.19 OAG26007.1 - 3.8e-20 72.6 11.5 3.8e-20 72.6 11.5 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAG26007.1 - 7.7e-06 26.1 0.8 2.7e-05 24.4 0.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ADD_ATRX PF17981.1 OAG26007.1 - 0.082 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Cysteine Rich ADD domain WD40 PF00400.32 OAG26008.1 - 8.9e-31 105.5 16.3 3.5e-07 30.8 1.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG26008.1 - 4.1e-11 43.0 0.8 0.021 15.1 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG26008.1 - 0.00045 20.1 0.2 0.082 12.8 0.1 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG26008.1 - 0.023 14.0 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 OAG26008.1 - 0.035 12.8 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like HK PF02110.15 OAG26009.1 - 8.2e-75 251.4 1.3 1.7e-74 250.3 1.3 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAG26009.1 - 1.2e-55 187.7 2.3 2e-55 186.9 2.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 OAG26009.1 - 0.0018 17.8 1.3 0.0034 16.9 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAG26009.1 - 0.019 14.4 0.1 0.053 12.9 0.1 1.8 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.17 OAG26010.1 - 5.9e-40 135.8 0.0 1.2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OAG26010.1 - 2.7e-17 62.7 1.2 2.7e-17 62.7 1.2 2.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Chalcone_3 PF16036.5 OAG26010.1 - 0.036 14.2 0.2 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 Chalcone isomerase-like SLC35F PF06027.12 OAG26011.1 - 5.2e-99 331.5 22.6 6.2e-99 331.3 22.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OAG26011.1 - 5.8e-10 38.6 4.5 1e-09 37.8 4.5 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OAG26011.1 - 0.0099 16.1 36.7 0.035 14.3 14.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family HCV_env PF01539.17 OAG26011.1 - 0.056 13.1 2.1 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 FUSC-like PF12805.7 OAG26011.1 - 2.4 7.2 7.2 0.37 9.8 1.2 2.4 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS zf-RING_2 PF13639.6 OAG26014.1 - 2.9e-08 33.9 1.3 2.9e-08 33.9 1.3 3.4 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OAG26014.1 - 2.7e-07 30.8 1.9 2.7e-07 30.8 1.9 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG26014.1 - 1.1e-05 25.1 1.9 1.1e-05 25.1 1.9 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG26014.1 - 4.8e-05 23.1 3.1 4.8e-05 23.1 3.1 2.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG26014.1 - 8.4e-05 22.4 0.3 8.4e-05 22.4 0.3 3.1 3 1 1 4 4 3 1 zinc-RING finger domain PHD PF00628.29 OAG26014.1 - 9.6e-05 22.2 18.6 9.9e-05 22.2 10.2 2.6 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 OAG26014.1 - 0.00011 22.0 0.9 0.00011 22.0 0.9 2.3 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG26014.1 - 0.00041 20.2 0.6 0.00041 20.2 0.6 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 OAG26014.1 - 0.0011 18.5 6.9 0.0024 17.4 6.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 OAG26014.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 OAG26014.1 - 0.025 14.8 0.1 0.025 14.8 0.1 1.8 2 0 0 2 2 1 0 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 OAG26014.1 - 3.1 7.5 13.2 0.52 10.0 1.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 OAG26014.1 - 3.1 7.7 12.9 0.038 13.9 3.9 2.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sacchrp_dh_NADP PF03435.18 OAG26015.1 - 1.1e-17 64.5 0.0 1.7e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Band_7_C PF16200.5 OAG26015.1 - 0.09 12.9 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of band_7 HET PF06985.11 OAG26016.1 - 1.7e-12 47.9 5.6 9.9e-08 32.5 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Med22 PF06179.12 OAG26017.1 - 7.3e-06 26.2 0.1 1.1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF812 PF05667.11 OAG26018.1 - 0.081 11.8 3.4 0.1 11.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) OAD_gamma PF04277.13 OAG26018.1 - 2.7 8.7 4.3 45 4.7 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LEA_1 PF03760.15 OAG26018.1 - 6.6 7.5 8.6 32 5.3 0.1 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 SMK-1 PF04802.15 OAG26021.1 - 6.3e-73 244.7 3.3 6.3e-73 244.7 3.3 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 DUF4704 PF15787.5 OAG26021.1 - 0.044 13.0 0.2 0.044 13.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) DHFR_1 PF00186.19 OAG26022.1 - 6.3e-29 100.7 0.0 5.1e-28 97.8 0.0 2.2 1 1 0 1 1 1 1 Dihydrofolate reductase DUF1132 PF06575.12 OAG26022.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) MAPEG PF01124.18 OAG26024.1 - 1.5e-18 66.9 2.3 1.9e-18 66.6 2.3 1.1 1 0 0 1 1 1 1 MAPEG family Lipase_3 PF01764.25 OAG26025.1 - 9.9e-20 70.9 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG26025.1 - 0.035 14.7 0.9 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family 1-cysPrx_C PF10417.9 OAG26025.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin PGAP1 PF07819.13 OAG26025.1 - 0.16 11.7 0.1 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Voltage_CLC PF00654.20 OAG26026.1 - 5.3e-89 298.9 28.4 5.3e-89 298.9 28.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG26026.1 - 0.00015 22.2 0.0 0.023 15.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain ADH_N PF08240.12 OAG26027.1 - 1.7e-26 92.2 0.5 3.8e-26 91.1 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG26027.1 - 1.6e-19 70.2 0.5 2.9e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG26027.1 - 1.5e-06 29.3 0.0 2.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase peroxidase PF00141.23 OAG26028.1 - 6.4e-83 277.9 0.0 1.1e-41 143.0 0.0 2.4 2 0 0 2 2 2 2 Peroxidase CNDH2_N PF06278.11 OAG26028.1 - 0.17 12.1 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF3181 PF11378.8 OAG26028.1 - 0.18 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) AMPK1_CBM PF16561.5 OAG26029.1 - 5.2e-06 26.6 0.2 1.3e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4791 PF16039.5 OAG26030.1 - 0.032 13.8 0.2 0.065 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) Peptidase_M48 PF01435.18 OAG26031.1 - 9.2e-34 116.9 0.0 1.9e-33 115.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Cutinase PF01083.22 OAG26032.1 - 4.6e-27 95.1 1.5 7.4e-27 94.4 1.5 1.3 1 0 0 1 1 1 1 Cutinase MFS_1 PF07690.16 OAG26036.1 - 2.6e-24 85.8 51.0 1.6e-19 70.1 32.7 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 OAG26036.1 - 0.43 9.1 28.8 9 4.7 13.3 2.5 1 1 1 2 2 2 0 MFS/sugar transport protein Zn_clus PF00172.18 OAG26037.1 - 1.3e-08 34.8 10.8 2.4e-08 34.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG26037.1 - 2e-08 33.5 0.1 2.8e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N_2 PF16884.5 OAG26038.1 - 3.6e-26 91.2 0.0 6.2e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG26038.1 - 2.4e-19 69.6 0.9 2.4e-19 69.6 0.9 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG26038.1 - 1.3e-07 32.7 0.0 2.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 OAG26038.1 - 0.033 13.9 0.4 0.2 11.4 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2855) SRP_TPR_like PF17004.5 OAG26039.1 - 3.4e-20 72.2 5.9 4.6e-20 71.8 3.7 2.1 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 OAG26039.1 - 4e-14 52.8 8.6 4e-14 52.8 8.6 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 OAG26039.1 - 2.5e-05 24.7 16.7 1.8 9.6 0.1 7.3 5 1 2 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG26039.1 - 8e-05 22.8 14.3 0.74 10.1 0.5 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAG26039.1 - 0.00023 21.6 25.5 0.25 11.9 1.3 7.3 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG26039.1 - 0.0047 17.2 10.0 1.8 8.9 2.3 5.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG26039.1 - 0.015 15.4 24.1 0.87 9.9 0.3 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF4012 PF13196.6 OAG26039.1 - 0.016 15.7 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) AcylCoA_dehyd_C PF12186.8 OAG26039.1 - 0.021 15.0 0.2 0.13 12.4 0.1 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal TPR_4 PF07721.14 OAG26039.1 - 0.036 14.7 4.8 1.5e+02 3.5 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5344 PF17279.2 OAG26039.1 - 0.072 13.7 3.9 0.14 12.8 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF4810 PF16068.5 OAG26039.1 - 0.084 13.4 0.9 0.45 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_16 PF13432.6 OAG26039.1 - 0.14 12.8 22.4 0.23 12.2 5.9 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAG26039.1 - 0.2 12.0 9.5 2.2 8.7 0.9 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG26039.1 - 2.4 8.6 17.6 14 6.2 0.1 6.1 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG26039.1 - 5.6 7.0 11.4 30 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TFIIE_alpha PF02002.17 OAG26040.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit DUF4611 PF15387.6 OAG26040.1 - 0.011 15.9 3.9 0.011 15.9 3.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Zn-ribbon_8 PF09723.10 OAG26040.1 - 0.17 12.0 0.4 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1660 PF07874.11 OAG26040.1 - 0.39 11.3 1.7 24 5.5 0.1 2.6 1 1 1 2 2 2 0 Prophage protein (DUF1660) TF_Zn_Ribbon PF08271.12 OAG26040.1 - 0.7 9.5 3.2 2.9 7.5 3.2 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding Mif2_N PF15624.6 OAG26040.1 - 1.3 9.7 7.6 1.5 9.5 2.3 2.3 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PseudoU_synth_1 PF01416.20 OAG26041.1 - 5.3e-09 36.5 0.0 1.9e-07 31.5 0.0 2.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 OAG26041.1 - 0.067 13.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Ku PF02735.16 OAG26042.1 - 1e-46 159.2 0.0 2.1e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAG26042.1 - 3e-35 122.0 0.0 5.3e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OAG26042.1 - 1.2e-26 93.2 0.7 1.2e-26 93.2 0.7 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 OAG26042.1 - 2.5e-09 36.6 0.1 5.3e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain Dockerin_1 PF00404.18 OAG26042.1 - 0.036 14.3 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 OAG26042.1 - 0.054 13.0 0.1 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 EF hand Ferrochelatase PF00762.19 OAG26043.1 - 1.2e-99 333.4 0.0 1.5e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase E1_dh PF00676.20 OAG26044.1 - 1.5e-116 388.6 0.4 1.7e-116 388.4 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAG26044.1 - 0.00086 18.6 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAG26044.1 - 0.027 14.2 1.4 0.058 13.2 1.4 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BMC PF00936.19 OAG26044.1 - 0.051 13.6 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 BMC domain HET PF06985.11 OAG26045.1 - 1.3e-05 25.6 1.2 2.5e-05 24.7 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EST1_DNA_bind PF10373.9 OAG26046.1 - 7.4e-14 51.9 0.1 2.5e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain MFS_1 PF07690.16 OAG26047.1 - 1.9e-21 76.4 17.4 1.9e-21 76.4 17.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily HATPase_c PF02518.26 OAG26047.1 - 6.6e-17 62.0 0.1 1.4e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG26047.1 - 8.7e-12 45.2 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG26047.1 - 4.6e-11 42.6 0.1 1.9e-10 40.6 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.24 OAG26047.1 - 3.2e-08 32.9 1.5 5.6e-08 32.1 1.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter GAF_2 PF13185.6 OAG26047.1 - 0.0056 17.0 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain MFS_3 PF05977.13 OAG26047.1 - 0.014 13.9 5.7 0.046 12.1 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF5326 PF17260.2 OAG26047.1 - 0.047 13.8 1.0 0.16 12.1 1.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5326) ECF_trnsprt PF12822.7 OAG26047.1 - 0.15 12.1 2.8 0.47 10.5 2.8 1.8 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Glycos_transf_2 PF00535.26 OAG26048.1 - 6.5e-25 87.9 0.0 2e-23 83.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG26048.1 - 1.6e-06 28.2 0.0 0.017 15.0 0.0 2.8 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Kelch_4 PF13418.6 OAG26049.1 - 1.1e-18 66.9 6.1 1.7e-07 31.1 0.1 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG26049.1 - 1.9e-18 66.2 12.2 0.00016 21.9 0.0 6.5 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG26049.1 - 1.1e-17 63.6 3.1 8.7e-05 22.4 0.0 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OAG26049.1 - 1.9e-17 62.9 0.4 0.00019 21.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OAG26049.1 - 2.9e-16 58.8 0.2 0.00042 19.8 0.2 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 OAG26049.1 - 1.3e-11 44.0 3.8 0.00073 19.4 0.0 4.6 5 0 0 5 5 5 3 Kelch motif CoA_transf_3 PF02515.17 OAG26050.1 - 3.4e-49 167.9 0.7 6.3e-47 160.5 0.2 2.4 2 1 0 2 2 2 2 CoA-transferase family III AAA_5 PF07728.14 OAG26051.1 - 3.5e-130 428.7 0.0 5.4e-23 81.5 0.0 10.3 10 0 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAG26051.1 - 1.2e-57 192.6 8.7 1.2e-26 92.9 0.0 6.0 6 0 0 6 6 4 4 Midasin AAA lid domain AAA_7 PF12775.7 OAG26051.1 - 2e-31 108.9 0.8 2.5e-06 27.1 0.0 7.4 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_3 PF07726.11 OAG26051.1 - 2.5e-30 105.0 0.0 4.6e-11 42.7 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 OAG26051.1 - 3.2e-30 105.3 0.0 0.00015 22.2 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG26051.1 - 2.2e-27 96.5 20.1 8.3e-05 23.0 0.2 9.7 8 2 0 8 8 6 6 AAA ATPase domain AAA_lid_5 PF17865.1 OAG26051.1 - 2.7e-27 94.9 0.0 3.2e-26 91.5 0.0 2.7 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_22 PF13401.6 OAG26051.1 - 8.5e-24 84.4 5.2 0.00027 21.2 0.0 9.0 9 1 0 9 9 7 4 AAA domain Dynein_heavy PF03028.15 OAG26051.1 - 1.1e-23 83.6 0.0 0.0012 19.0 0.0 8.7 10 0 0 10 10 6 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 OAG26051.1 - 3e-23 82.4 0.0 0.0008 19.1 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_18 PF13238.6 OAG26051.1 - 1.4e-22 80.6 0.2 0.00077 20.0 0.0 7.3 6 0 0 6 6 6 5 AAA domain Sigma54_activ_2 PF14532.6 OAG26051.1 - 9.9e-21 74.3 0.2 0.00046 20.3 0.0 6.9 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 OAG26051.1 - 1e-17 64.1 0.0 0.0043 16.1 0.0 8.6 9 0 0 9 9 9 3 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 OAG26051.1 - 3.1e-17 62.5 3.8 0.0012 17.9 0.0 6.4 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_30 PF13604.6 OAG26051.1 - 1.6e-16 60.6 0.5 0.1 12.3 0.0 9.1 9 2 0 9 9 7 2 AAA domain AAA_14 PF13173.6 OAG26051.1 - 1.7e-16 60.5 0.0 0.0022 18.0 0.0 8.0 8 0 0 8 8 7 2 AAA domain TsaE PF02367.17 OAG26051.1 - 3.6e-16 59.3 2.5 0.092 12.8 0.0 6.8 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAG26051.1 - 7.9e-16 58.5 0.1 0.088 13.0 0.0 7.1 6 0 0 6 6 6 3 AAA domain RNA_helicase PF00910.22 OAG26051.1 - 6.5e-15 55.4 1.6 0.26 11.7 0.0 6.8 6 0 0 6 6 6 3 RNA helicase RuvB_N PF05496.12 OAG26051.1 - 3.2e-14 53.0 1.3 0.024 14.4 0.0 6.4 7 0 0 7 7 5 3 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG26051.1 - 3.8e-13 49.3 0.1 0.49 9.7 0.0 9.0 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAG26051.1 - 1.4e-12 47.8 3.3 0.19 11.6 0.1 6.5 6 0 0 6 6 6 2 NACHT domain AAA_19 PF13245.6 OAG26051.1 - 1.6e-11 44.8 4.5 1.5 9.1 0.0 7.4 6 1 0 6 6 6 2 AAA domain Rad17 PF03215.15 OAG26051.1 - 4e-11 43.2 0.1 0.97 9.3 0.0 5.6 5 0 0 5 5 5 2 Rad17 P-loop domain Zeta_toxin PF06414.12 OAG26051.1 - 4.7e-11 42.3 0.0 2 7.7 0.0 6.7 6 0 0 6 6 6 1 Zeta toxin ABC_tran PF00005.27 OAG26051.1 - 9.5e-11 42.4 18.2 0.022 15.2 0.0 8.2 9 0 0 9 9 6 3 ABC transporter AAA_25 PF13481.6 OAG26051.1 - 1.6e-10 40.9 4.2 1.3 8.6 0.0 6.3 6 0 0 6 6 5 3 AAA domain ATPase_2 PF01637.18 OAG26051.1 - 3.2e-10 40.3 0.0 1.2 8.9 0.0 6.2 6 0 0 6 6 5 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OAG26051.1 - 3.3e-10 40.4 8.5 1.7 8.9 0.0 7.5 7 0 0 7 7 7 1 AAA domain ResIII PF04851.15 OAG26051.1 - 1e-09 38.6 0.2 0.65 10.0 0.0 6.8 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OAG26051.1 - 1.5e-09 37.8 0.3 1.7 8.4 0.0 6.4 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_29 PF13555.6 OAG26051.1 - 1.9e-09 37.1 3.3 2 8.2 0.0 7.7 8 0 0 8 8 6 1 P-loop containing region of AAA domain SRP54 PF00448.22 OAG26051.1 - 8.1e-09 35.4 1.7 1.6 8.3 0.0 6.0 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain ATPase PF06745.13 OAG26051.1 - 9.3e-08 31.7 5.4 0.018 14.4 0.0 6.3 7 0 0 7 7 5 1 KaiC RsgA_GTPase PF03193.16 OAG26051.1 - 1.3e-07 31.6 11.4 0.63 9.9 0.1 7.2 8 0 0 8 8 6 1 RsgA GTPase AAA_24 PF13479.6 OAG26051.1 - 2e-07 31.0 0.3 4.2 7.0 0.0 6.5 6 1 0 6 6 6 0 AAA domain PduV-EutP PF10662.9 OAG26051.1 - 2.2e-07 30.7 2.1 0.033 14.0 0.0 6.0 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OAG26051.1 - 7.9e-07 29.2 0.3 7 6.8 0.0 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase TniB PF05621.11 OAG26051.1 - 1.4e-06 27.8 0.1 1.8 7.9 0.0 5.6 6 0 0 6 6 5 1 Bacterial TniB protein SRPRB PF09439.10 OAG26051.1 - 5.4e-06 26.0 0.7 1.8 8.0 0.0 6.0 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG26051.1 - 1.1e-05 25.7 2.4 34 4.7 0.0 6.0 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 OAG26051.1 - 1.3e-05 24.6 0.4 0.31 10.2 0.0 5.2 6 0 0 6 6 5 1 TIP49 P-loop domain NTPase_1 PF03266.15 OAG26051.1 - 1.3e-05 25.2 6.8 1.8 8.5 0.1 5.9 5 0 0 5 5 5 1 NTPase Viral_helicase1 PF01443.18 OAG26051.1 - 1.3e-05 25.1 0.0 9.1 5.9 0.0 5.9 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAG26051.1 - 1.4e-05 24.6 0.2 7.9 5.9 0.0 5.6 7 0 0 7 7 5 0 PhoH-like protein DUF815 PF05673.13 OAG26051.1 - 1.7e-05 24.1 0.1 5.9 6.0 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF815) cobW PF02492.19 OAG26051.1 - 2.2e-05 24.1 7.0 1.6 8.3 0.0 6.0 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 OAG26051.1 - 5.7e-05 23.1 6.3 1.6 8.6 0.1 5.7 6 0 0 6 6 5 1 Deoxynucleoside kinase KAP_NTPase PF07693.14 OAG26051.1 - 7.2e-05 22.2 0.0 4.9 6.3 0.0 5.0 4 0 0 4 4 4 0 KAP family P-loop domain ATP_bind_1 PF03029.17 OAG26051.1 - 0.00016 21.5 4.4 4.7 6.9 0.0 5.8 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 OAG26051.1 - 0.00044 20.1 0.0 8.3 6.1 0.0 5.0 5 0 0 5 5 4 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 OAG26051.1 - 0.0013 18.2 0.1 12 5.2 0.0 4.8 5 0 0 5 5 4 0 FtsK/SpoIIIE family VWA PF00092.28 OAG26051.1 - 0.0016 18.8 0.1 0.0052 17.1 0.1 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG26051.1 - 0.0024 18.5 0.1 0.081 13.6 0.1 3.9 3 0 0 3 3 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OAG26051.1 - 0.0061 16.7 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus Thymidylate_kin PF02223.17 OAG26051.1 - 0.0067 16.1 2.7 2.4 7.8 0.0 5.2 6 0 0 6 6 5 1 Thymidylate kinase KTI12 PF08433.10 OAG26051.1 - 0.0084 15.6 0.0 51 3.2 0.0 4.7 5 0 0 5 5 4 0 Chromatin associated protein KTI12 Bac_DnaA PF00308.18 OAG26051.1 - 0.029 14.2 0.1 70 3.1 0.0 4.3 6 0 0 6 6 3 0 Bacterial dnaA protein CPT PF07931.12 OAG26051.1 - 0.04 13.8 0.8 37 4.1 0.0 4.9 5 1 0 5 5 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 OAG26051.1 - 0.043 13.5 0.1 38 3.9 0.0 4.7 4 0 0 4 4 4 0 Cytidylate kinase ATP-synt_ab PF00006.25 OAG26051.1 - 0.05 13.2 0.0 1.7 8.2 0.0 3.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 OAG26051.1 - 0.12 12.2 0.6 7.2 6.5 0.0 3.9 5 0 0 5 5 3 0 Adenylylsulphate kinase FeoB_N PF02421.18 OAG26051.1 - 0.13 11.8 2.9 13 5.2 0.1 3.7 4 0 0 4 4 3 0 Ferrous iron transport protein B Hairy_orange PF07527.13 OAG26051.1 - 0.15 12.3 1.6 0.73 10.1 1.1 2.5 2 0 0 2 2 1 0 Hairy Orange CbiA PF01656.23 OAG26051.1 - 0.21 11.7 3.1 9.4 6.3 0.2 4.6 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain tRNA_lig_kinase PF08303.11 OAG26051.1 - 0.66 10.1 3.9 0.68 10.0 0.1 2.7 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF853 PF05872.12 OAG26051.1 - 1.3 7.6 9.9 0.59 8.7 0.0 3.3 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) MobB PF03205.14 OAG26051.1 - 2 8.3 8.6 91 3.0 0.1 5.9 7 0 0 7 7 6 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 OAG26051.1 - 5.4 7.0 7.0 24 4.9 0.0 4.6 4 0 0 4 4 2 0 Helicase HerA, central domain CTK3 PF12243.8 OAG26052.1 - 9.1e-48 161.3 0.3 1.4e-47 160.8 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAG26052.1 - 6.7e-21 74.2 11.6 1.4e-20 73.2 11.6 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Kinase-PolyVal PF18762.1 OAG26052.1 - 0.045 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins KfrA_N PF11740.8 OAG26052.1 - 0.083 13.6 2.1 0.25 12.0 2.1 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term P5CR_dimer PF14748.6 OAG26053.1 - 3e-35 120.6 3.5 5.4e-35 119.8 3.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG26053.1 - 8.8e-07 29.4 0.0 3.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Say1_Mug180 PF10340.9 OAG26055.1 - 3.8e-25 88.5 0.0 5.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 OAG26055.1 - 1.8e-22 80.2 0.0 2.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 OAG26056.1 - 1.9e-27 95.8 0.3 1.9e-27 95.8 0.3 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG26056.1 - 6.7e-22 77.4 0.4 1.7e-21 76.2 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG26056.1 - 0.002 19.2 0.0 0.0038 18.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG26056.1 - 0.083 12.8 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase AbiGi PF10899.8 OAG26056.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin Abhydrolase_1 PF00561.20 OAG26057.1 - 4.5e-48 164.1 0.0 1.7e-47 162.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG26057.1 - 0.0008 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAG26057.1 - 0.012 16.2 4.7 0.023 15.3 4.7 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG26057.1 - 0.11 11.8 0.0 0.9 8.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ketoacyl-synt PF00109.26 OAG26059.1 - 8.6e-61 205.7 0.3 1.9e-59 201.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG26059.1 - 1.8e-36 124.7 0.5 3.4e-36 123.9 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.18 OAG26059.1 - 4.8e-06 26.2 0.5 0.0014 18.3 0.1 2.7 2 0 0 2 2 2 2 Thiolase, C-terminal domain Thiolase_N PF00108.23 OAG26059.1 - 2.3e-05 23.9 0.2 0.00059 19.3 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain NicO PF03824.16 OAG26060.1 - 1.9e-66 224.3 10.2 3.3e-66 223.5 10.2 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein GAPT PF11770.8 OAG26060.1 - 0.11 12.4 0.5 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DHHC PF01529.20 OAG26060.1 - 0.91 9.6 9.2 15 5.7 0.3 3.5 2 1 2 4 4 4 0 DHHC palmitoyltransferase CAF1 PF04857.20 OAG26061.1 - 2.4e-70 237.3 0.1 1e-69 235.2 0.0 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 OAG26061.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 3'-5' exonuclease TMEM214 PF10151.9 OAG26061.1 - 1.2 7.5 3.9 2.1 6.7 3.9 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Pro-rich PF15240.6 OAG26062.1 - 0.0041 17.4 10.0 0.006 16.9 9.3 1.7 2 0 0 2 2 2 1 Proline-rich Asp-B-Hydro_N PF05279.11 OAG26062.1 - 0.25 11.4 8.7 0.34 10.9 8.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 OAG26062.1 - 0.31 9.3 9.6 0.42 8.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex26 PF07163.12 OAG26062.1 - 0.59 9.4 5.0 0.36 10.1 3.2 1.5 2 0 0 2 2 2 0 Pex26 protein SMN PF06003.12 OAG26062.1 - 1.4 8.1 6.4 1.3 8.2 4.9 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Rrn6 PF10214.9 OAG26062.1 - 2.9 6.3 14.7 0.17 10.3 9.5 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SpoVR PF04293.13 OAG26062.1 - 5.7 5.5 8.0 8.9 4.9 8.0 1.2 1 0 0 1 1 1 0 SpoVR like protein U79_P34 PF03064.16 OAG26062.1 - 5.9 6.2 15.6 11 5.2 15.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4554 PF15091.6 OAG26062.1 - 9.7 5.0 6.1 15 4.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LRR_6 PF13516.6 OAG26063.1 - 0.023 14.7 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat PTPLA PF04387.14 OAG26064.1 - 3.7e-48 163.4 10.5 5.6e-48 162.8 10.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Abhydrolase_6 PF12697.7 OAG26066.1 - 3.8e-19 70.2 0.2 4.4e-19 70.0 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OAG26066.1 - 0.043 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 OAG26066.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 OAG26066.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-RING_2 PF13639.6 OAG26067.1 - 2.8e-07 30.8 11.2 7.3e-07 29.4 11.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG26067.1 - 1.1e-05 25.4 7.9 1.1e-05 25.4 7.9 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG26067.1 - 2.1e-05 24.7 14.1 0.0001 22.5 14.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG26067.1 - 5.1e-05 23.1 10.5 0.0001 22.2 10.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAG26067.1 - 0.00039 20.4 6.9 0.00039 20.4 6.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG26067.1 - 0.0008 19.2 10.3 0.0008 19.2 10.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG26067.1 - 0.008 15.8 11.4 0.02 14.5 11.4 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAG26067.1 - 0.014 15.1 3.6 0.074 12.8 3.6 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG26067.1 - 0.29 11.0 17.9 6.5 6.7 16.4 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG26067.1 - 0.35 10.8 11.2 1.5 8.7 11.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG26067.1 - 0.82 9.6 10.2 2.1 8.3 10.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 OAG26067.1 - 0.9 9.4 6.9 2.9 7.8 3.3 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OAG26067.1 - 1.2 9.3 13.3 0.69 10.1 10.7 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 OAG26067.1 - 1.9 8.7 11.3 2 8.6 9.2 2.2 2 1 0 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 OAG26067.1 - 4.2 7.3 15.0 2.9 7.8 7.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 OAG26068.1 - 0.0027 18.1 15.0 0.0046 17.4 1.2 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger DUF4662 PF15578.6 OAG26069.1 - 0.052 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Abhydrolase_1 PF00561.20 OAG26071.1 - 1.4e-10 41.2 0.2 5e-09 36.2 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG26071.1 - 1.7e-05 24.2 0.4 4.2e-05 22.9 0.4 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG26071.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain TPP_enzyme_C PF02775.21 OAG26071.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_4 PF08386.10 OAG26071.1 - 0.14 12.3 0.0 1.1 9.4 0.0 2.3 3 1 0 3 3 3 0 TAP-like protein FAD_binding_3 PF01494.19 OAG26073.1 - 1.1e-13 51.2 0.7 3.6e-12 46.2 0.7 2.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG26073.1 - 8.6e-10 38.3 0.3 1.9e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG26073.1 - 3.9e-09 36.5 0.4 0.00043 20.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG26073.1 - 1.6e-07 30.4 0.7 2.3e-05 23.3 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAG26073.1 - 1.9e-07 30.6 0.3 3e-07 29.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG26073.1 - 1.1e-06 28.7 0.1 1.2e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG26073.1 - 1.4e-06 27.8 0.1 1.2e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG26073.1 - 3.1e-06 26.8 0.4 5.7e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG26073.1 - 1.9e-05 24.0 0.1 3.3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG26073.1 - 0.013 16.1 0.4 0.29 11.7 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG26073.1 - 0.023 13.8 2.2 0.18 10.8 2.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG26073.1 - 0.042 12.7 1.3 0.88 8.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OAG26073.1 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAG26073.1 - 0.076 12.3 0.2 6.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG26073.1 - 0.27 10.4 1.5 0.34 10.1 0.4 1.6 2 0 0 2 2 2 0 Thi4 family COesterase PF00135.28 OAG26074.1 - 1.6e-88 297.8 0.0 2.1e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG26074.1 - 4.8e-07 29.9 0.1 3.6e-06 27.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG26074.1 - 0.0074 15.8 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family EVE PF01878.18 OAG26075.1 - 1.7e-48 164.3 0.1 3.3e-48 163.4 0.1 1.5 1 0 0 1 1 1 1 EVE domain Roughex PF06020.11 OAG26075.1 - 4.6 6.2 8.2 7 5.6 8.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Abhydrolase_1 PF00561.20 OAG26076.1 - 8.9e-19 68.1 0.0 3e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG26076.1 - 3.4e-12 47.4 0.0 4.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG26076.1 - 7.8e-06 25.3 0.0 3.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG26076.1 - 0.0026 16.5 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family zf-C3HC4 PF00097.25 OAG26077.1 - 1.7e-07 31.0 6.6 1.7e-07 31.0 6.6 4.6 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAG26077.1 - 1.1e-06 28.4 0.4 1.1e-06 28.4 0.4 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OAG26077.1 - 1.9e-06 28.1 6.9 1.9e-06 28.1 6.9 4.2 4 1 0 4 4 4 1 Ring finger domain ZZ PF00569.17 OAG26077.1 - 2e-06 27.5 5.5 2e-06 27.5 5.5 4.1 5 0 0 5 5 5 2 Zinc finger, ZZ type zf-RING_UBOX PF13445.6 OAG26077.1 - 2.6e-06 27.3 5.6 2.6e-06 27.3 5.6 3.4 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG26077.1 - 8.5e-06 25.5 8.0 8.5e-06 25.5 8.0 4.3 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG26077.1 - 0.00017 21.7 8.4 0.00017 21.7 8.4 4.2 5 2 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAG26077.1 - 0.00041 20.3 5.6 0.00041 20.3 5.6 5.3 5 1 0 5 5 5 1 zinc-RING finger domain SH3_9 PF14604.6 OAG26077.1 - 0.067 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain K-cyclin_vir_C PF09080.10 OAG26078.1 - 0.2 12.1 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 K cyclin, C terminal Hexapep PF00132.24 OAG26079.1 - 1.1e-13 50.3 11.5 1.9e-09 36.9 6.6 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG26079.1 - 6.1e-12 45.1 8.7 8.7e-10 38.2 6.0 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAG26079.1 - 2.5e-11 43.6 0.2 4.5e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.14 OAG26080.1 - 5.6e-29 100.4 0.2 1.1e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG26080.1 - 7.9e-13 48.7 2.8 7.9e-13 48.7 2.8 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAG26080.1 - 8.1e-07 28.8 1.7 1.1e-06 28.3 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 OAG26080.1 - 1.1e-05 25.0 0.7 2.5e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 NnrU protein PAF-AH_p_II PF03403.13 OAG26083.1 - 7.8e-12 44.4 0.0 0.00018 20.1 0.0 3.2 4 0 0 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAG26083.1 - 7.7e-08 31.9 0.0 7.9e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG26083.1 - 3.2e-05 24.6 0.4 3.2e-05 24.6 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OAG26083.1 - 0.00011 22.0 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG26083.1 - 0.0002 21.1 0.9 0.0044 16.7 0.4 2.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Beta_helix_2 PF18835.1 OAG26083.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase MFS_1 PF07690.16 OAG26084.1 - 6.2e-40 137.2 61.4 4.2e-39 134.5 58.8 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG26084.1 - 1.2e-05 24.3 13.8 1.2e-05 24.3 13.8 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter Aminotran_4 PF01063.19 OAG26085.1 - 3.5e-20 72.8 0.0 4.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Methyltransf_31 PF13847.6 OAG26087.1 - 1.6e-09 37.7 0.0 2.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG26087.1 - 1.2e-08 35.5 0.0 2.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG26087.1 - 1.7e-06 27.5 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG26087.1 - 0.00044 20.2 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 OAG26087.1 - 0.00044 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG26087.1 - 0.0039 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_33 PF10017.9 OAG26087.1 - 0.034 13.3 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MTS PF05175.14 OAG26087.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF3669 PF12417.8 OAG26088.1 - 1.9e-25 88.8 0.0 3.5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Terpene_synth_C PF03936.16 OAG26089.1 - 9.9e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2236 PF09995.9 OAG26091.1 - 1.4e-28 100.6 0.0 2.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2384 PF09722.10 OAG26093.1 - 0.16 12.0 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Sec7_N PF12783.7 OAG26094.1 - 0.00051 20.0 0.7 23 4.8 0.0 4.5 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 OAG26094.1 - 0.0027 17.8 1.9 4.1 7.9 0.0 4.8 3 0 0 3 3 3 1 HEAT repeat RTP1_C1 PF10363.9 OAG26094.1 - 0.09 13.0 0.0 3.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4404 PF14357.6 OAG26094.1 - 0.2 12.3 0.9 62 4.3 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) HEAT PF02985.22 OAG26095.1 - 0.0001 22.3 0.1 0.26 11.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OAG26095.1 - 0.00074 19.6 0.0 0.11 12.5 0.0 3.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG26095.1 - 0.0071 16.8 0.8 0.44 11.1 0.0 4.3 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 OAG26095.1 - 0.017 15.5 0.0 1 9.8 0.0 4.1 5 1 1 6 6 6 0 HEAT repeats Nipped-B_C PF12830.7 OAG26095.1 - 0.087 12.8 0.0 7.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus MFS_1 PF07690.16 OAG26097.1 - 4.9e-55 186.9 53.9 2.2e-46 158.4 38.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG26097.1 - 1.4e-11 43.6 17.9 3.3e-11 42.3 17.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG26097.1 - 1.4e-10 40.6 5.7 1.4e-10 40.6 5.7 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 OAG26097.1 - 9.1e-05 21.9 4.1 9.1e-05 21.9 4.1 2.3 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB HlyIII PF03006.20 OAG26097.1 - 0.014 15.1 1.0 0.014 15.1 1.0 2.4 1 1 2 3 3 3 0 Haemolysin-III related DUF1430 PF07242.11 OAG26097.1 - 0.026 14.8 2.7 0.032 14.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Amidase PF01425.21 OAG26098.1 - 1.1e-85 288.3 0.3 1.3e-85 288.0 0.3 1.0 1 0 0 1 1 1 1 Amidase PhetRS_B1 PF18262.1 OAG26098.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Polysacc_deac_1 PF01522.21 OAG26099.1 - 1.5e-12 47.4 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Transp_cyt_pur PF02133.15 OAG26100.1 - 2.6e-86 290.1 37.4 3.2e-86 289.8 37.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HET PF06985.11 OAG26101.1 - 1.7e-12 47.9 5.9 5.4e-10 39.8 1.2 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PX PF00787.24 OAG26102.1 - 1.5e-16 60.3 0.0 4.1e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAG26102.1 - 1.4e-07 31.3 10.8 0.00022 20.9 1.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Ribosomal_S24e PF01282.19 OAG26103.1 - 1.8e-35 120.8 0.2 2.2e-35 120.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 OAG26104.1 - 5.3e-21 75.1 0.0 9.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAG26104.1 - 6.3e-07 29.1 0.1 9.8e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG26104.1 - 0.00012 21.6 0.2 0.00023 20.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAG26104.1 - 0.0016 19.1 0.1 0.0033 18.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG26104.1 - 0.044 14.5 0.0 0.085 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 OAG26104.1 - 0.087 12.8 0.5 0.33 10.9 0.5 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.19 OAG26104.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ecl1 PF12855.7 OAG26105.1 - 1.1e-38 134.1 22.6 1.1e-38 134.1 22.6 2.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAG26105.1 - 0.0031 17.6 1.1 0.007 16.4 1.1 1.5 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 OAG26105.1 - 0.78 9.3 3.2 3.8 7.0 3.2 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 OAG26105.1 - 2.9 8.1 5.1 1.5 9.0 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Cerato-platanin PF07249.12 OAG26106.1 - 1.2e-60 202.9 4.0 1.4e-60 202.6 4.0 1.1 1 0 0 1 1 1 1 Cerato-platanin Copper-bind PF00127.20 OAG26108.1 - 0.00032 21.1 0.1 0.0006 20.2 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 OAG26108.1 - 0.032 14.3 0.2 0.075 13.2 0.1 1.6 2 0 0 2 2 2 0 Cupredoxin-like domain Cu_bind_like PF02298.17 OAG26108.1 - 0.044 13.8 0.6 0.46 10.5 0.6 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain ADH_N PF08240.12 OAG26109.1 - 9.9e-10 38.3 0.5 2.1e-09 37.3 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG26109.1 - 3.2e-08 33.6 0.8 5.5e-08 32.9 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 OAG26109.1 - 0.12 12.2 0.2 0.31 10.8 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Mpv17_PMP22 PF04117.12 OAG26111.1 - 2.9e-17 62.6 0.7 6.6e-17 61.5 0.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF829 PF05705.14 OAG26112.1 - 2.6e-55 187.9 0.2 3e-55 187.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ifi-6-16 PF06140.13 OAG26113.1 - 3.3e-08 33.3 22.1 4.5e-08 32.9 22.1 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family ASFV_J13L PF05568.11 OAG26113.1 - 0.19 11.5 1.9 0.15 11.8 0.6 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein LRR_4 PF12799.7 OAG26114.1 - 0.03 14.8 0.7 11 6.6 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) SNARE PF05739.19 OAG26115.1 - 2.6e-13 49.7 0.5 5.9e-13 48.6 0.5 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 OAG26115.1 - 0.0015 18.9 10.9 0.029 14.7 5.1 2.4 2 0 0 2 2 2 2 Syntaxin-like protein EBV-NA3 PF05009.12 OAG26115.1 - 0.0027 17.3 0.1 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Syntaxin PF00804.25 OAG26115.1 - 0.015 15.0 13.8 0.045 13.4 0.4 2.4 3 0 0 3 3 3 0 Syntaxin DNA_repr_REX1B PF14966.6 OAG26115.1 - 0.25 12.0 3.5 0.62 10.8 0.2 3.0 2 2 2 4 4 4 0 DNA repair REX1-B MCPsignal PF00015.21 OAG26115.1 - 0.3 10.9 7.7 0.095 12.5 0.5 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF812 PF05667.11 OAG26115.1 - 1 8.1 14.9 0.29 10.0 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) SlyX PF04102.12 OAG26115.1 - 1.3 9.7 15.5 1.3 9.7 0.6 3.9 2 2 1 3 3 3 0 SlyX EF-hand_1 PF00036.32 OAG26116.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAG26116.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAG26116.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OAG26116.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAG26116.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAG26116.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAG26116.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAG26116.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAG26116.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OAG26116.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OAG26116.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 OAG26116.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 OAG26116.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OAG26116.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 OAG26116.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 OAG26116.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 OAG26116.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 OAG26116.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 OAG26116.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 OAG26116.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAG26116.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 OAG26116.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 OAG26116.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 OAG26116.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 OAG26116.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 OAG26116.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein PH_10 PF15411.6 OAG26118.1 - 7.5e-28 97.3 0.1 1.3e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAG26118.1 - 2.5e-12 47.4 0.0 3.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAG26118.1 - 3.4e-08 33.6 0.1 1.7e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 OAG26118.1 - 6.5e-05 23.2 8.1 0.00012 22.4 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 OAG26118.1 - 0.0031 17.1 4.6 0.0031 17.1 4.6 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAG26118.1 - 0.011 15.7 8.4 0.019 14.9 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG26118.1 - 0.011 15.5 7.0 0.022 14.6 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 OAG26118.1 - 0.017 15.6 0.0 0.052 14.1 0.0 1.8 1 0 0 1 1 1 0 PH domain zf-RING_11 PF17123.5 OAG26118.1 - 0.02 14.6 4.3 0.04 13.7 4.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 OAG26118.1 - 0.041 14.2 4.2 0.085 13.2 4.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG26118.1 - 0.12 12.3 8.7 0.21 11.5 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_A3 PF02160.15 OAG26118.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) zf-RING-like PF08746.11 OAG26118.1 - 0.14 12.4 8.0 0.25 11.7 8.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.6 OAG26118.1 - 0.15 12.2 1.9 0.27 11.4 1.9 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OAG26118.1 - 0.39 10.6 4.9 0.74 9.7 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Abhydrolase_1 PF00561.20 OAG26119.1 - 1.4e-15 57.7 0.0 8.4e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG26119.1 - 3.1e-10 39.7 0.0 2.4e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG26119.1 - 3.4e-08 34.4 0.0 4.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAG26119.1 - 0.0014 17.4 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_2 PF02230.16 OAG26119.1 - 0.0026 17.6 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 OAG26119.1 - 0.054 12.2 0.0 4.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ADH_N PF08240.12 OAG26120.1 - 1.1e-23 83.2 4.0 1.7e-23 82.6 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG26120.1 - 7.9e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG26120.1 - 5e-08 34.1 0.0 1.1e-07 33.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG26120.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG26120.1 - 0.0034 16.8 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAG26121.1 - 4.2e-39 134.4 0.0 6.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OAG26121.1 - 0.0023 18.2 0.3 0.0023 18.2 0.3 2.2 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG26121.1 - 0.0035 17.6 0.2 0.03 14.6 0.0 2.6 3 0 0 3 3 3 1 TrkA-N domain Gly_kinase PF02595.15 OAG26121.1 - 0.058 12.4 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycerate kinase family NAD_binding_7 PF13241.6 OAG26121.1 - 0.066 13.7 0.4 3.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Coatomer_E PF04733.14 OAG26121.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit UDPG_MGDP_dh_N PF03721.14 OAG26121.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Endonuclease_NS PF01223.23 OAG26122.1 - 9.6e-67 225.1 0.0 1.2e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-Tim10_DDP PF02953.15 OAG26123.1 - 1.4e-24 85.5 1.6 1.6e-24 85.3 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_4 PF08386.10 OAG26123.1 - 0.054 13.6 0.1 0.4 10.8 0.1 2.0 1 1 0 1 1 1 0 TAP-like protein Lectin_leg-like PF03388.13 OAG26124.1 - 7e-67 225.1 0.0 1.4e-66 224.2 0.0 1.4 1 1 1 2 2 2 1 Legume-like lectin family Bact_lectin PF18483.1 OAG26124.1 - 4.4e-08 33.4 0.4 6.6e-08 32.8 0.4 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 OAG26124.1 - 2e-05 24.3 0.1 0.012 15.1 0.0 2.2 1 1 0 2 2 2 2 Legume lectin domain Tyrosinase PF00264.20 OAG26125.1 - 9.4e-51 173.2 0.1 1.2e-50 172.8 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase SKG6 PF08693.10 OAG26126.1 - 9.5e-07 28.1 0.5 1.6e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RicinB_lectin_2 PF14200.6 OAG26126.1 - 0.0015 19.2 8.6 0.0057 17.4 0.6 3.1 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like TMEM51 PF15345.6 OAG26126.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1491 PF07372.12 OAG26126.1 - 0.092 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) NOC3p PF07540.11 OAG26127.1 - 4.4e-32 110.4 2.3 1.3e-31 108.9 1.1 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OAG26127.1 - 3.8e-26 92.1 0.0 3.8e-26 92.1 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family HEAT_2 PF13646.6 OAG26127.1 - 0.034 14.5 0.6 7.4 7.0 0.1 3.3 3 0 0 3 3 3 0 HEAT repeats FERM_M PF00373.18 OAG26127.1 - 0.15 12.5 5.2 1 9.8 1.3 2.6 2 0 0 2 2 2 0 FERM central domain UPF0113 PF03657.13 OAG26128.1 - 4.2e-26 91.0 0.0 8.8e-26 90.0 0.0 1.5 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 OAG26128.1 - 4e-25 88.2 0.0 5.5e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 OAG26128.1 - 0.0032 17.4 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 PUA domain Isy1 PF06246.12 OAG26129.1 - 6.1e-92 307.8 2.6 6.8e-92 307.6 2.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family zf-CCCH PF00642.24 OAG26130.1 - 1.3e-08 34.5 2.8 2.5e-08 33.6 2.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 OAG26130.1 - 3e-08 33.4 6.9 5.2e-08 32.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG26130.1 - 2e-07 30.9 6.7 4.2e-07 29.9 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG26130.1 - 7.4e-07 28.9 8.9 1.5e-06 28.0 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG26130.1 - 1.3e-06 28.2 10.9 2.4e-06 27.3 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG26130.1 - 2.8e-06 27.2 9.2 4.8e-06 26.4 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 OAG26130.1 - 5e-06 26.6 4.5 5e-06 26.6 4.5 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 OAG26130.1 - 1.6e-05 24.7 6.2 3.3e-05 23.8 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 OAG26130.1 - 0.0001 22.5 7.8 0.0002 21.6 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 OAG26130.1 - 0.00018 21.2 2.6 0.00018 21.2 2.6 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 OAG26130.1 - 0.00064 19.5 5.9 0.0012 18.7 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG26130.1 - 0.017 15.2 8.8 0.043 14.0 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 OAG26130.1 - 0.075 13.5 3.6 0.16 12.4 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-Nse PF11789.8 OAG26130.1 - 0.13 12.1 2.6 0.23 11.3 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Peptidase_Prp PF04327.12 OAG26130.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Cysteine protease Prp zf-rbx1 PF12678.7 OAG26130.1 - 0.17 12.2 4.8 0.38 11.1 4.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain ATP-synt_E PF05680.12 OAG26130.1 - 1.9 8.9 5.9 1 9.7 1.3 2.4 2 0 0 2 2 2 0 ATP synthase E chain AGH PF17558.2 OAG26132.1 - 0.39 10.9 1.5 1.1 9.5 1.5 1.7 1 0 0 1 1 1 0 Androgenic gland hormone Abhydrolase_6 PF12697.7 OAG26133.1 - 3.2e-13 50.8 0.3 4.4e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG26133.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tnp_22_dsRBD PF17490.2 OAG26133.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Acetate_kinase PF00871.17 OAG26135.1 - 7.5e-97 324.5 0.0 8.8e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family TACC_C PF05010.14 OAG26135.1 - 0.039 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal adh_short PF00106.25 OAG26136.1 - 5.1e-24 84.8 0.0 2.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26136.1 - 3.8e-15 56.1 0.0 6.8e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG26136.1 - 0.0071 15.8 0.1 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG26136.1 - 0.097 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAP_assoc PF03828.19 OAG26138.1 - 3.8e-16 59.0 0.0 1.2e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG26138.1 - 5.2e-06 26.7 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG26138.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Striatin PF08232.12 OAG26138.1 - 0.25 11.9 0.1 0.25 11.9 0.1 3.3 3 0 0 3 3 3 0 Striatin family Isochorismatase PF00857.20 OAG26139.1 - 3.1e-31 108.9 0.0 4.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_1 PF00583.25 OAG26141.1 - 3.4e-08 33.7 0.0 4.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG26141.1 - 0.0003 21.2 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG26141.1 - 0.0034 17.3 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAG26141.1 - 0.072 12.6 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Amino_oxidase PF01593.24 OAG26142.1 - 4e-56 191.2 0.0 4.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG26142.1 - 2.2e-15 56.6 0.2 5e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG26142.1 - 3.6e-05 23.1 0.0 0.0001 21.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG26142.1 - 6e-05 22.8 1.9 6e-05 22.8 1.9 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG26142.1 - 9e-05 23.0 0.3 0.00049 20.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG26142.1 - 0.00015 21.0 0.2 0.00029 20.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG26142.1 - 0.00022 20.1 0.2 0.0034 16.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG26142.1 - 0.00035 20.1 0.0 0.00092 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG26142.1 - 0.00081 18.7 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAG26142.1 - 0.00091 18.6 0.7 0.0015 17.9 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG26142.1 - 0.003 16.8 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG26142.1 - 0.012 14.9 0.7 0.063 12.5 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG26142.1 - 0.019 14.0 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 OAG26142.1 - 0.045 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 MCRA family 2-Hacid_dh_C PF02826.19 OAG26142.1 - 0.18 11.2 0.2 0.31 10.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG26142.1 - 0.2 11.5 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.7 OAG26143.1 - 6.4e-34 116.4 0.0 1.9e-08 34.8 0.0 5.1 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG26143.1 - 3.6e-29 100.7 0.1 4.3e-08 33.5 0.0 6.1 5 2 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG26143.1 - 8.3e-24 81.1 0.2 0.0024 18.2 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OAG26143.1 - 4e-14 52.5 0.1 0.078 13.3 0.0 6.6 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG26143.1 - 1.1e-13 50.9 0.2 0.022 15.2 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat TPR_4 PF07721.14 OAG26143.1 - 0.17 12.6 0.4 0.68 10.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 OAG26146.1 - 6.2e-43 147.1 0.0 1.7e-42 145.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG26146.1 - 2e-27 96.1 0.0 3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG26146.1 - 0.0045 15.8 0.0 0.0086 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FapA PF03961.13 OAG26147.1 - 0.047 12.3 4.3 0.08 11.5 4.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 OAG26147.1 - 0.22 11.6 1.5 0.44 10.6 1.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.12 OAG26147.1 - 2.2 8.0 5.5 4 7.2 5.5 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein COG2 PF06148.11 OAG26147.1 - 2.7 8.1 4.3 18 5.4 0.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 OAG26147.1 - 4.1 7.5 6.1 8.2 6.5 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Muted PF14942.6 OAG26147.1 - 6.1 7.2 9.5 12 6.2 8.7 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Ras PF00071.22 OAG26148.1 - 4.6e-53 179.1 0.0 5.8e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG26148.1 - 5.2e-19 68.6 0.0 8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG26148.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_clus PF00172.18 OAG26149.1 - 1.7e-13 50.4 29.8 1.3e-06 28.4 9.7 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 OAG26149.1 - 1.1 8.0 2.0 1.8 7.3 2.0 1.2 1 0 0 1 1 1 0 Presenilin Glyco_hydro_3_C PF01915.22 OAG26150.1 - 1e-57 195.4 0.1 1.9e-57 194.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain GATase PF00117.28 OAG26150.1 - 5.8e-45 153.4 0.0 9.4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAG26150.1 - 6.8e-45 152.0 0.0 1.6e-44 150.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Glyco_hydro_3 PF00933.21 OAG26150.1 - 2.6e-39 135.5 0.0 5.3e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG26150.1 - 4.9e-24 84.2 0.0 1.1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain 2-oxogl_dehyd_N PF16078.5 OAG26150.1 - 0.0019 17.8 0.1 0.072 12.7 0.0 2.4 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Peptidase_C26 PF07722.13 OAG26150.1 - 0.0086 15.9 0.4 0.04 13.7 0.1 2.0 1 1 0 2 2 2 1 Peptidase C26 Ser_hydrolase PF06821.13 OAG26150.1 - 0.054 13.4 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Serine hydrolase DJ-1_PfpI PF01965.24 OAG26150.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family CENP-Q PF13094.6 OAG26151.1 - 0.44 10.7 11.3 0.17 12.1 4.6 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SHE3 PF17078.5 OAG26151.1 - 0.6 9.8 7.5 8.2 6.1 4.9 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 BRD4_CDT PF17105.5 OAG26151.1 - 1 9.0 3.1 2.7 7.7 3.1 1.8 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 V_ATPase_I PF01496.19 OAG26151.1 - 1.4 6.8 4.3 2.6 5.9 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 OAG26151.1 - 4.3 8.0 6.2 24 5.6 2.4 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Lebercilin PF15619.6 OAG26151.1 - 5.9 6.5 16.7 2.4 7.8 0.4 2.7 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease VASt PF16016.5 OAG26152.1 - 2.2e-33 115.8 0.0 4.1e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAG26152.1 - 1.2e-22 80.0 0.1 8.5e-22 77.2 0.0 2.1 2 0 0 2 2 2 1 GRAM domain DUF2070 PF09843.9 OAG26153.1 - 3.8 5.7 11.4 4.9 5.3 11.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3552 PF12072.8 OAG26154.1 - 0.0018 17.7 16.8 0.0032 16.9 16.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) zf_CCCH_4 PF18345.1 OAG26154.1 - 1.1 9.4 5.2 0.75 9.9 2.1 2.0 2 0 0 2 2 2 0 Zinc finger domain DUF4200 PF13863.6 OAG26154.1 - 7.6 7.0 17.1 1.2 9.6 5.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MBDa PF16564.5 OAG26155.1 - 0.048 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Tmemb_170 PF10190.9 OAG26156.1 - 3.1e-13 50.0 11.5 7.8e-13 48.7 11.5 1.6 1 1 0 1 1 1 1 Putative transmembrane protein 170 zf-C3HC4_3 PF13920.6 OAG26157.1 - 4.6e-11 42.4 9.0 4.6e-11 42.4 9.0 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG26157.1 - 3.7e-06 26.7 5.0 3.7e-06 26.7 5.0 2.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG26157.1 - 0.00051 19.9 6.9 0.00051 19.9 6.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain NUDIX PF00293.28 OAG26158.1 - 6.4e-07 29.5 0.1 1.6e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.18 OAG26159.1 - 3.1e-05 24.0 11.6 5.7e-05 23.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG26159.1 - 0.0013 17.8 0.1 0.0081 15.2 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG26160.1 - 3.2e-19 69.0 0.5 3.2e-19 69.0 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26160.1 - 2.6e-09 37.1 6.9 5.8e-09 35.9 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAT PF03417.16 OAG26161.1 - 3e-28 99.0 0.0 3.7e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Polysacc_deac_1 PF01522.21 OAG26162.1 - 1.5e-22 79.8 0.0 2.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG26162.1 - 4e-14 52.8 1.0 1.1e-13 51.3 0.9 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG26162.1 - 2.8e-08 33.4 0.1 4.6e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 OAG26162.1 - 0.00026 19.5 0.1 0.00033 19.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Mito_carr PF00153.27 OAG26163.1 - 7.5e-48 160.4 6.0 1e-16 60.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 OAG26164.1 - 8.1e-36 123.8 0.3 2.1e-35 122.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 OAG26164.1 - 9e-26 90.6 0.0 2.4e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH_1 PF13423.6 OAG26164.1 - 1.6e-21 77.2 0.1 3.3e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 OAG26165.1 - 6.4e-08 32.8 0.0 0.0018 18.4 0.0 3.1 2 1 0 2 2 2 2 RNase P subunit Pop3 Abhydrolase_1 PF00561.20 OAG26166.1 - 2.6e-46 158.4 0.0 7.9e-46 156.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG26166.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase WD40 PF00400.32 OAG26167.1 - 3.4e-39 132.1 24.6 1.3e-07 32.2 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 OAG26167.1 - 8e-11 41.7 0.8 1.4e-10 40.9 0.8 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAG26167.1 - 1.1e-08 35.2 0.9 0.19 12.1 0.0 5.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG26167.1 - 2.3e-08 33.2 3.8 1.3 7.5 0.0 5.8 1 1 5 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 OAG26167.1 - 5.3e-07 29.4 0.6 1e-06 28.5 0.6 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 OAG26167.1 - 0.00043 19.7 0.0 0.02 14.2 0.0 2.7 1 1 3 4 4 4 2 WD40-like domain DUF853 PF05872.12 OAG26167.1 - 0.16 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) LamB_YcsF PF03746.16 OAG26168.1 - 3.9e-85 285.4 0.0 4.4e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 OAG26169.1 - 5.1e-79 265.6 0.0 7.6e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 OAG26169.1 - 2.6e-55 187.2 0.1 6.6e-55 185.9 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG26169.1 - 8.2e-40 135.8 0.1 2.8e-39 134.1 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 OAG26169.1 - 1.2e-34 119.9 0.0 2.3e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 OAG26169.1 - 3e-31 107.7 0.0 5.8e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG26169.1 - 1.8e-08 34.1 3.4 8e-08 32.0 3.4 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG26169.1 - 2.3e-07 30.6 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAG26169.1 - 0.0002 21.1 0.9 0.054 13.3 0.2 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 OAG26169.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PreAtp-grasp PF18604.1 OAG26169.1 - 0.15 11.7 0.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Pre ATP-grasp domain Radical_SAM PF04055.21 OAG26170.1 - 7.9e-06 26.3 0.1 0.00015 22.2 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Phi-29_GP4 PF05464.11 OAG26170.1 - 0.028 14.7 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) DUF948 PF06103.11 OAG26171.1 - 0.00033 20.8 5.2 1.2 9.5 0.1 4.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Hydrolase_6 PF13344.6 OAG26171.1 - 0.011 15.8 1.2 7.9 6.7 0.1 3.2 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF1547 PF07577.11 OAG26171.1 - 0.15 12.4 10.4 16 6.0 0.3 3.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) ILVD_EDD PF00920.21 OAG26172.1 - 1.6e-213 710.0 0.6 1.9e-213 709.8 0.6 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 OAG26172.1 - 0.0035 17.6 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Glyco_hydro_53 PF07745.13 OAG26173.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_42 PF02449.15 OAG26173.1 - 0.049 13.0 0.4 0.1 11.9 0.2 1.5 2 0 0 2 2 2 0 Beta-galactosidase Glyco_hydro_17 PF00332.18 OAG26173.1 - 0.1 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 RRM_1 PF00076.22 OAG26174.1 - 1.1e-27 95.7 0.0 1.2e-14 53.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG26174.1 - 0.00054 19.5 0.0 0.54 9.9 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG26174.1 - 0.0027 17.8 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 OAG26174.1 - 0.14 12.2 0.0 23 5.1 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 FAD_binding_1 PF00667.20 OAG26175.1 - 1e-33 116.8 0.0 2e-33 115.8 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG26175.1 - 2.1e-27 96.1 0.0 4.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG26175.1 - 6.8e-14 52.4 0.0 1.8e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG26175.1 - 0.0043 17.3 0.0 1.6 9.0 0.0 2.5 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_3 PF12641.7 OAG26175.1 - 0.013 15.2 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain POPLD PF08170.12 OAG26175.1 - 0.15 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 POPLD (NUC188) domain Tyrosinase PF00264.20 OAG26176.1 - 8e-48 163.6 0.3 1e-47 163.3 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.7 OAG26177.1 - 4.4e-07 29.7 0.8 1e-06 28.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG26177.1 - 0.00015 21.5 0.4 0.0008 19.2 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG26178.1 - 1.4e-06 28.0 0.1 3.8e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG26178.1 - 0.00064 19.5 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain bVLRF1 PF18826.1 OAG26179.1 - 7.2e-61 204.4 0.2 7.2e-61 204.4 0.2 1.8 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank PF00023.30 OAG26179.1 - 0.0013 19.1 0.2 0.0032 17.8 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OAG26179.1 - 0.0014 18.9 0.4 0.0042 17.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG26179.1 - 0.011 16.2 0.0 0.032 14.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_3rep PF18868.1 OAG26179.1 - 0.11 13.2 1.1 0.42 11.3 0.0 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ank_2 PF12796.7 OAG26179.1 - 0.11 13.0 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RPA43_OB PF17875.1 OAG26179.1 - 2.7 8.6 7.4 0.86 10.2 2.5 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I SseC PF04888.12 OAG26181.1 - 0.2 11.2 3.4 0.26 10.9 3.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Zip PF02535.22 OAG26182.1 - 1.5e-27 96.7 31.2 5.5e-21 75.1 9.0 3.9 2 1 1 3 3 3 3 ZIP Zinc transporter Hat1_N PF10394.9 OAG26183.1 - 5.9e-37 127.4 0.2 9.1e-36 123.5 0.0 2.4 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Spc7 PF08317.11 OAG26183.1 - 0.014 14.3 2.6 0.02 13.8 1.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Acetyltransf_1 PF00583.25 OAG26183.1 - 0.021 15.1 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Formyl_trans_N PF00551.19 OAG26184.1 - 1.2e-41 142.4 0.1 1.5e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase EBP PF05241.12 OAG26185.1 - 1.2e-68 230.0 10.3 1.5e-68 229.8 10.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein TatC PF00902.18 OAG26185.1 - 0.031 14.1 0.5 0.031 14.1 0.5 1.7 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) CBM_21 PF03370.13 OAG26186.1 - 1.8e-36 124.7 3.3 3e-36 124.0 3.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAG26186.1 - 9.1e-09 35.8 2.9 1.9e-08 34.8 2.9 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) BolA PF01722.18 OAG26188.1 - 2.2e-11 43.9 0.0 5.4e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF3671 PF12420.8 OAG26189.1 - 0.065 13.3 1.4 0.58 10.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function TMEM107 PF14995.6 OAG26189.1 - 0.087 13.3 2.1 0.34 11.4 1.6 2.3 2 0 0 2 2 2 0 Transmembrane protein DUF4293 PF14126.6 OAG26189.1 - 0.17 12.2 3.4 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Glyco_hydro_11 PF00457.17 OAG26190.1 - 4.3e-81 270.8 18.8 5e-81 270.6 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 U-box PF04564.15 OAG26191.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 U-box domain Peptidase_C8 PF03569.13 OAG26191.1 - 0.22 11.1 2.3 0.38 10.3 2.3 1.3 1 0 0 1 1 1 0 Peptidase family C8 OmpH PF03938.14 OAG26191.1 - 0.27 11.6 5.3 0.51 10.7 5.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2040 PF09745.9 OAG26192.1 - 8.7e-37 125.9 28.3 8.7e-37 125.9 28.3 4.0 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) PRCC PF10253.9 OAG26193.1 - 1.5e-29 104.3 1.9 1.5e-29 104.3 1.9 3.0 3 2 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting CRIM PF16978.5 OAG26194.1 - 8.6e-41 139.4 0.0 1.9e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAG26194.1 - 1.6e-29 102.4 0.1 3e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 OAG26194.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain PBP1_TM PF14812.6 OAG26194.1 - 4.2 7.8 7.6 0.58 10.6 2.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lipase_GDSL_2 PF13472.6 OAG26195.1 - 3.9e-23 82.8 0.3 6.3e-23 82.1 0.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG26195.1 - 9.4e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LMSTEN PF07988.12 OAG26195.1 - 0.26 10.8 0.1 0.46 10.0 0.1 1.3 1 0 0 1 1 1 0 LMSTEN motif CBFD_NFYB_HMF PF00808.23 OAG26196.1 - 1.3e-14 54.2 0.9 3e-14 53.0 0.9 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG26196.1 - 0.00029 21.2 3.5 0.0003 21.2 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Acyltransferase PF01553.21 OAG26197.1 - 3.3e-14 52.6 0.0 8.3e-14 51.4 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase zf-NOSIP PF15906.5 OAG26198.1 - 1.3e-05 25.2 0.0 3.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 OAG26198.1 - 4.1e-05 23.5 2.9 4.1e-05 23.5 2.9 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG26198.1 - 4.4e-05 23.7 17.2 0.00052 20.3 6.7 2.8 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 OAG26198.1 - 8.4e-05 22.5 6.8 8.4e-05 22.5 6.8 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG26198.1 - 0.0008 19.2 19.8 0.0027 17.5 8.1 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG26198.1 - 0.00088 19.1 3.8 0.00088 19.1 3.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG26198.1 - 0.0021 17.9 6.7 0.0021 17.9 6.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OAG26198.1 - 0.004 17.3 10.8 0.022 14.9 5.8 3.0 2 1 0 2 2 2 1 FYVE zinc finger Prok-RING_4 PF14447.6 OAG26198.1 - 1.6 8.6 21.4 1 9.2 8.7 3.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 OAG26198.1 - 3 7.9 13.2 8.1 6.5 3.9 3.4 2 1 0 2 2 2 0 zinc-ribbons zf-C3HC4_4 PF15227.6 OAG26198.1 - 3.5 7.9 18.3 0.1 12.8 6.1 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.16 OAG26199.1 - 6.5e-29 100.9 37.0 6.5e-29 100.9 37.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MRI PF15325.6 OAG26199.1 - 2.9 9.0 4.4 4.9 8.3 4.4 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Ecm33 PF12454.8 OAG26200.1 - 0.019 15.1 0.2 0.049 13.8 0.2 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein SAP PF02037.27 OAG26201.1 - 2.3e-09 36.8 0.6 5.6e-09 35.5 0.2 2.0 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 OAG26201.1 - 3.3e-07 30.5 0.2 3.3e-07 30.5 0.2 4.1 3 1 1 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Solute_trans_a PF03619.16 OAG26202.1 - 1.5e-72 244.3 14.3 1.9e-72 244.0 14.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1422 PF07226.11 OAG26202.1 - 0.035 14.1 6.6 0.042 13.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) Fungal_trans_2 PF11951.8 OAG26203.1 - 8.1e-19 67.7 0.4 3.3e-18 65.7 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26203.1 - 2.4e-09 37.2 11.5 3.9e-09 36.5 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 OAG26204.1 - 1.7e-119 398.7 0.1 3.2e-119 397.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG26204.1 - 5.8e-37 127.1 0.0 1.2e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG26204.1 - 8.4e-08 32.1 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG26204.1 - 1.7e-06 27.5 0.1 6.8e-05 22.2 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 OAG26204.1 - 2.8e-05 23.2 0.1 4.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component LssY_C PF14067.6 OAG26204.1 - 0.18 11.4 0.0 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 LssY C-terminus MRP-L46 PF11788.8 OAG26206.1 - 8.8e-38 129.7 0.2 1.8e-37 128.7 0.2 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cpn60_TCP1 PF00118.24 OAG26207.1 - 4.9e-151 503.7 15.4 5.6e-151 503.5 15.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 OAG26207.1 - 0.014 15.0 1.6 0.027 14.0 0.1 2.2 3 0 0 3 3 3 0 Propionate catabolism activator EAL PF00563.20 OAG26207.1 - 0.014 14.9 0.1 0.038 13.5 0.0 1.7 2 0 0 2 2 2 0 EAL domain Nitro_FeMo-Co PF02579.17 OAG26207.1 - 0.02 15.2 0.0 0.076 13.4 0.0 2.0 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DUF2204 PF09970.9 OAG26207.1 - 0.062 12.9 0.2 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Pyr_redox_2 PF07992.14 OAG26209.1 - 4.9e-36 124.5 0.0 6.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG26209.1 - 8.6e-14 51.9 0.5 4.9e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG26209.1 - 2.9e-06 26.8 0.1 7e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG26209.1 - 1.7e-05 24.8 0.2 1.1 9.2 0.1 3.9 4 1 1 5 5 5 2 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG26209.1 - 0.00053 18.8 0.6 0.15 10.7 0.0 3.3 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 OAG26209.1 - 0.00061 19.5 0.0 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG26209.1 - 0.0012 18.1 0.3 0.0086 15.2 0.1 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAG26209.1 - 0.0089 14.9 0.0 0.28 10.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 OAG26209.1 - 0.015 14.5 0.2 4.4 6.5 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.24 OAG26209.1 - 0.027 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG26209.1 - 0.17 10.9 0.1 4.6 6.2 0.1 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein RAI16-like PF10257.9 OAG26210.1 - 5.8e-84 282.0 1.3 1e-83 281.2 1.3 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein KinB_sensor PF16767.5 OAG26210.1 - 0.11 12.9 1.9 0.19 12.2 0.3 2.2 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Mito_carr PF00153.27 OAG26211.1 - 1.2e-68 227.1 1.7 1.8e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 OAG26212.1 - 3.9e-38 130.0 0.0 3.6e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein U3_snoRNA_assoc PF08297.11 OAG26213.1 - 2.6e-18 66.5 5.2 2.6e-18 66.5 5.2 5.7 3 2 0 3 3 3 1 U3 snoRNA associated TPR_6 PF13174.6 OAG26214.1 - 5.9e-06 26.6 0.8 0.24 12.1 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG26214.1 - 5.3e-05 23.1 2.6 0.17 12.2 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG26214.1 - 0.00048 20.3 0.1 38 5.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG26214.1 - 0.00065 19.6 4.7 0.1 12.8 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG26214.1 - 0.00065 20.3 1.2 6.8 7.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG26214.1 - 0.11 12.6 0.7 3.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 OAG26214.1 - 0.15 11.8 0.1 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 OAG26214.1 - 0.21 11.5 2.5 7.8 6.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG26214.1 - 0.22 11.4 4.0 0.4 10.6 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Isochorismatase PF00857.20 OAG26215.1 - 1.5e-27 96.9 0.0 5.5e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Isochorismatase family Cmyb_C PF09316.10 OAG26215.1 - 0.1 12.3 0.4 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 C-myb, C-terminal ETF PF01012.21 OAG26216.1 - 4.3e-39 134.3 2.7 5.2e-39 134.0 2.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF896 PF05979.12 OAG26217.1 - 0.11 12.4 0.6 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Nucleoside_tran PF01733.18 OAG26219.1 - 1.2e-43 149.7 13.0 1.8e-41 142.5 13.0 2.4 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 OAG26219.1 - 7.1e-06 25.2 39.2 0.0079 15.2 9.1 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily PalH PF08733.10 OAG26219.1 - 0.047 12.7 0.1 0.047 12.7 0.1 1.9 1 1 0 1 1 1 0 PalH/RIM21 TMEM251 PF15190.6 OAG26219.1 - 0.067 13.1 0.2 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 251 Iwr1 PF08574.10 OAG26220.1 - 1.4e-16 61.3 13.9 1.4e-16 61.3 13.9 2.8 2 0 0 2 2 2 1 Transcription factor Iwr1 Nop14 PF04147.12 OAG26220.1 - 2.3 6.3 9.4 2.7 6.1 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family SCA7 PF08313.12 OAG26221.1 - 9e-31 105.6 0.2 9e-31 105.6 0.2 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 OAG26221.1 - 0.032 13.8 1.0 0.052 13.1 1.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CDC45 PF02724.14 OAG26221.1 - 0.32 9.2 4.7 0.41 8.9 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ac76 PF05814.11 OAG26221.1 - 0.74 9.9 1.9 1.9 8.6 1.9 1.7 1 0 0 1 1 1 0 Orf76 (Ac76) Alg6_Alg8 PF03155.15 OAG26222.1 - 3.9e-170 567.0 24.2 5.3e-170 566.5 24.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 OAG26222.1 - 1.3e-39 134.7 1.1 1.3e-39 134.7 1.1 2.7 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAG26222.1 - 4.9e-21 75.1 3.8 8e-21 74.4 0.1 2.8 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAG26222.1 - 3.4e-14 52.9 0.7 8e-14 51.7 0.7 1.6 1 0 0 1 1 1 1 DDT domain DUF5097 PF17020.5 OAG26222.1 - 0.003 17.9 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5097) RRM_1 PF00076.22 OAG26223.1 - 1.1e-37 127.7 0.0 1.3e-11 44.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG26223.1 - 1.2e-13 50.6 0.0 0.0054 16.6 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 OAG26223.1 - 5.5e-09 35.6 5.7 5.5e-09 35.6 5.7 4.9 5 1 0 5 5 5 1 Putative RRM domain DUF4523 PF15023.6 OAG26223.1 - 2.1e-05 24.4 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 OAG26223.1 - 0.0007 19.7 0.4 0.66 10.1 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 OAG26223.1 - 0.0086 16.1 4.7 0.61 10.2 0.1 3.3 4 0 0 4 4 4 2 RNA binding motif DUF1387 PF07139.11 OAG26223.1 - 3.4 7.3 7.5 6.5 6.4 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 OAG26223.1 - 3.6 6.3 4.6 5.3 5.7 4.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 OAG26223.1 - 4.9 7.4 8.7 9.8 6.4 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Med20 PF08612.11 OAG26224.1 - 1.5e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Peptidase_S41 PF03572.18 OAG26225.1 - 4.3e-09 36.1 0.0 1.1e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 SR-25 PF10500.9 OAG26227.1 - 1.5 8.3 7.0 1.9 8.0 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glucosamine_iso PF01182.20 OAG26228.1 - 1.6e-66 224.4 0.0 1.8e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AAA_22 PF13401.6 OAG26228.1 - 0.17 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.25 OAG26229.1 - 0.11 12.1 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Syntaxin CbbQ_C PF08406.10 OAG26230.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal HALZ PF02183.18 OAG26231.1 - 0.00056 20.1 4.5 0.68 10.2 0.2 3.6 3 0 0 3 3 3 2 Homeobox associated leucine zipper Cep57_MT_bd PF06657.13 OAG26231.1 - 0.0026 18.2 7.9 0.73 10.3 0.3 3.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 OAG26231.1 - 0.0033 16.4 16.0 0.0081 15.1 13.4 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OAG26231.1 - 0.0038 17.3 15.6 0.45 10.5 11.0 3.1 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OAG26231.1 - 0.0046 17.4 13.9 0.049 14.1 11.7 2.0 2 0 0 2 2 2 1 Fez1 DUF4618 PF15397.6 OAG26231.1 - 0.0069 15.8 0.1 0.0069 15.8 0.1 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) ATG16 PF08614.11 OAG26231.1 - 0.027 14.7 16.7 0.68 10.1 11.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 OAG26231.1 - 0.034 12.3 14.4 0.058 11.5 12.2 1.9 1 1 1 2 2 2 0 HOOK protein TMF_TATA_bd PF12325.8 OAG26231.1 - 0.035 14.3 16.5 2 8.6 4.6 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Leu_zip PF15294.6 OAG26231.1 - 0.037 13.6 11.1 2.3 7.7 7.9 2.2 2 0 0 2 2 2 0 Leucine zipper BLOC1_2 PF10046.9 OAG26231.1 - 0.043 14.1 13.5 9 6.7 1.3 4.1 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 OAG26231.1 - 0.046 13.8 13.0 0.56 10.3 6.9 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Spectrin PF00435.21 OAG26231.1 - 0.063 13.8 13.4 1 9.9 1.7 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF4407 PF14362.6 OAG26231.1 - 0.07 12.5 9.4 1.3 8.3 9.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 OAG26231.1 - 0.11 11.8 17.1 1.3 8.4 1.1 3.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 OAG26231.1 - 0.12 12.6 10.4 0.81 9.9 0.0 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 OAG26231.1 - 0.12 12.8 8.1 8.5 6.9 1.0 3.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 OAG26231.1 - 0.14 11.9 13.1 0.47 10.2 9.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF724 PF05266.14 OAG26231.1 - 0.15 11.8 11.4 0.45 10.3 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 OAG26231.1 - 0.19 11.5 0.0 0.19 11.5 0.0 4.2 2 1 2 4 4 4 0 Septum formation initiator DUF2721 PF11026.8 OAG26231.1 - 0.22 11.4 1.3 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) HAUS-augmin3 PF14932.6 OAG26231.1 - 0.23 11.0 14.9 0.6 9.6 5.1 3.0 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 OAG26231.1 - 0.26 11.8 18.6 0.15 12.6 11.4 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 OAG26231.1 - 0.31 10.1 11.2 3 6.8 0.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vps51 PF08700.11 OAG26231.1 - 0.36 11.0 9.2 1.2 9.3 0.3 3.5 3 1 0 3 3 3 0 Vps51/Vps67 HIP1_clath_bdg PF16515.5 OAG26231.1 - 0.39 11.3 16.3 0.67 10.6 5.6 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 OAG26231.1 - 0.43 10.6 18.2 0.2 11.7 7.1 3.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Sec34 PF04136.15 OAG26231.1 - 0.44 10.4 8.6 13 5.6 0.0 2.9 2 1 0 3 3 3 0 Sec34-like family Prp19 PF08606.11 OAG26231.1 - 0.49 10.4 5.3 1.6 8.8 0.4 3.0 3 0 0 3 3 3 0 Prp19/Pso4-like FapA PF03961.13 OAG26231.1 - 0.5 8.9 10.2 0.89 8.1 7.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 OAG26231.1 - 0.54 10.3 6.9 11 6.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OAG26231.1 - 0.61 10.2 22.8 17 5.5 0.1 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 OAG26231.1 - 0.62 9.6 17.6 2.8 7.4 0.1 2.8 2 1 0 2 2 2 0 Intermediate filament protein P4Ha_N PF08336.11 OAG26231.1 - 0.63 10.0 0.1 0.63 10.0 0.1 2.7 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prominin PF05478.11 OAG26231.1 - 0.73 7.7 6.4 4 5.3 0.0 2.0 2 0 0 2 2 2 0 Prominin CENP-H PF05837.12 OAG26231.1 - 0.73 10.3 13.6 7.9 6.9 8.4 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 OAG26231.1 - 0.79 9.8 16.3 12 6.0 5.2 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Mvb12 PF09452.10 OAG26231.1 - 0.88 10.0 3.1 9 6.8 0.6 2.6 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 zf-C4H2 PF10146.9 OAG26231.1 - 1.4 9.2 7.8 2.2 8.6 4.8 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DUF5082 PF16888.5 OAG26231.1 - 2.2 8.5 15.3 1.1 9.6 3.7 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 OAG26231.1 - 3.3 8.3 7.4 11 6.6 0.1 3.5 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OAG26231.1 - 3.5 8.2 12.5 34 5.0 4.2 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 Tup_N PF08581.10 OAG26231.1 - 3.5 8.0 11.2 13 6.2 3.9 3.7 2 1 2 4 4 3 0 Tup N-terminal TMF_DNA_bd PF12329.8 OAG26231.1 - 3.8 7.6 14.2 6.7 6.8 0.0 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 OAG26231.1 - 4.3 8.0 12.0 21 5.8 1.5 3.3 2 1 1 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 OAG26231.1 - 4.6 6.5 21.4 6.4 6.0 4.9 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 OAG26231.1 - 5.4 7.5 16.6 49 4.4 13.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FUSC PF04632.12 OAG26231.1 - 6.8 5.1 5.7 6.7 5.1 3.4 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Uso1_p115_C PF04871.13 OAG26231.1 - 8.4 6.8 14.1 15 5.9 3.8 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region BolA PF01722.18 OAG26232.1 - 5.4e-30 103.5 1.5 6.7e-30 103.2 1.5 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 OAG26233.1 - 7.1e-69 232.4 0.0 9e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG26233.1 - 1.5e-13 51.5 0.1 3.4e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1996 PF09362.10 OAG26237.1 - 2.6e-60 204.3 4.2 3.4e-60 204.0 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 OAG26237.1 - 0.014 15.7 1.3 0.21 11.9 0.1 2.6 2 0 0 2 2 2 0 Galactose mutarotase-like Glyco_hydro_11 PF00457.17 OAG26238.1 - 4.1e-67 225.3 5.4 4.5e-67 225.1 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 KR PF08659.10 OAG26239.1 - 3.7e-06 27.0 0.0 5.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG26239.1 - 8.4e-05 22.1 0.0 0.00017 21.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26240.1 - 2.5e-62 210.5 0.0 2.9e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG26240.1 - 5.1e-49 166.4 0.0 6.2e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG26240.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF4690 PF15756.5 OAG26241.1 - 0.002 18.7 1.1 0.002 18.7 1.1 1.7 2 1 0 2 2 2 1 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 OAG26241.1 - 0.021 14.8 1.4 0.041 13.8 1.4 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CYYR1 PF10873.8 OAG26241.1 - 0.064 13.7 0.0 0.084 13.3 0.0 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 PTP_tm PF18861.1 OAG26241.1 - 0.29 11.1 2.7 0.49 10.4 2.7 1.6 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF1996 PF09362.10 OAG26243.1 - 4.5e-81 272.3 1.0 5.6e-81 272.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Amidase PF01425.21 OAG26244.1 - 1e-56 192.8 0.7 5.3e-51 174.0 0.4 2.1 2 0 0 2 2 2 2 Amidase PEX11 PF05648.14 OAG26244.1 - 7.3e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1678 PF07913.11 OAG26245.1 - 0.0057 16.4 1.2 0.0061 16.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1678) HrpA_pilin PF09589.10 OAG26245.1 - 0.0087 16.7 0.1 0.01 16.5 0.1 1.2 1 0 0 1 1 1 1 HrpA pilus formation protein DUF2277 PF10041.9 OAG26245.1 - 0.11 12.8 0.6 0.26 11.6 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) Atg14 PF10186.9 OAG26245.1 - 1.3 8.0 5.5 1.4 7.9 5.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNAD3 PF18749.1 OAG26246.1 - 0.03 13.5 0.2 0.039 13.1 0.2 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 DUF1899 PF08953.11 OAG26247.1 - 9.8e-36 121.5 0.1 1.8e-35 120.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAG26247.1 - 8.3e-20 70.4 0.1 1.6e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OAG26247.1 - 2.2e-16 59.9 7.2 6.6e-06 26.8 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG26247.1 - 1.1e-05 25.7 0.1 0.0066 16.7 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SlyX PF04102.12 OAG26247.1 - 0.0091 16.6 6.0 0.021 15.5 6.0 1.6 1 0 0 1 1 1 1 SlyX Nup160 PF11715.8 OAG26247.1 - 0.016 13.9 4.3 0.17 10.5 0.1 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PKcGMP_CC PF16808.5 OAG26247.1 - 1.6 8.6 4.5 3.6 7.5 4.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4404 PF14357.6 OAG26247.1 - 3 8.6 6.8 13 6.5 6.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Zn_clus PF00172.18 OAG26248.1 - 0.25 11.5 11.1 0.49 10.6 11.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 OAG26249.1 - 2.4e-12 47.8 0.2 3.7e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG26249.1 - 3.9e-05 23.9 0.5 0.00017 21.8 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Sec23_trunk PF04811.15 OAG26249.1 - 0.1 12.2 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Ras PF00071.22 OAG26250.1 - 7.2e-19 68.0 0.1 1.6e-18 66.8 0.1 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG26250.1 - 0.0007 19.8 0.3 0.01 16.0 0.1 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAG26250.1 - 0.016 14.9 0.4 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 OAG26251.1 - 1.5e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG26251.1 - 3e-11 43.5 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG26251.1 - 2e-08 34.4 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG26251.1 - 2.3e-07 30.9 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG26251.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG26251.1 - 0.0035 17.6 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OAG26251.1 - 0.017 15.8 0.0 0.049 14.4 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain RTA1 PF04479.13 OAG26252.1 - 8.2e-55 185.6 7.1 8.2e-55 185.6 7.1 1.6 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 OAG26253.1 - 1.3e-07 31.7 9.3 2.7e-07 30.6 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG26253.1 - 0.019 13.8 0.6 0.029 13.2 0.6 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 OAG26254.1 - 4e-32 111.3 0.0 5e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26254.1 - 1.4e-23 83.7 0.1 2e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG26254.1 - 0.00019 20.9 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAG26254.1 - 0.00022 21.2 0.0 0.00047 20.1 0.0 1.6 2 0 0 2 2 2 1 KR domain NUDIX PF00293.28 OAG26256.1 - 8.5e-16 58.2 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3328 PF11807.8 OAG26257.1 - 0.022 14.5 0.5 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) OAD_gamma PF04277.13 OAG26257.1 - 0.06 13.9 1.1 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SE PF08491.10 OAG26258.1 - 7.5e-102 340.1 0.0 9.7e-102 339.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 OAG26258.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG26258.1 - 7.2e-07 29.1 0.3 0.00016 21.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG26258.1 - 5.7e-05 22.7 0.3 9.2e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG26258.1 - 0.00015 21.1 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAG26258.1 - 0.00017 20.8 2.7 0.0023 17.1 2.7 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG26258.1 - 0.00047 19.4 0.4 0.00084 18.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG26258.1 - 0.0041 16.4 0.3 0.017 14.4 0.1 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG26258.1 - 0.0046 17.2 0.6 0.0093 16.2 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG26258.1 - 0.0071 15.3 0.2 0.65 8.8 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG26258.1 - 0.032 14.8 0.2 0.075 13.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG26258.1 - 0.033 12.9 0.3 0.049 12.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1349 PF07081.11 OAG26261.1 - 6.4e-25 87.9 0.0 7.8e-24 84.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) DUF4688 PF15752.5 OAG26261.1 - 0.0069 15.7 0.1 0.009 15.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4688) Bin3 PF06859.12 OAG26262.1 - 8.4e-26 90.7 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 OAG26262.1 - 2.6e-09 37.1 0.0 3.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG26262.1 - 3e-08 34.3 0.0 4e-06 27.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG26262.1 - 5.5e-08 32.7 0.3 0.028 14.2 0.6 3.5 2 2 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAG26262.1 - 1.2e-07 32.3 0.3 0.31 11.8 0.0 4.0 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAG26262.1 - 3e-06 27.8 0.2 0.074 13.7 0.0 3.9 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_PK PF05891.12 OAG26262.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 OAG26262.1 - 0.015 14.9 0.0 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 OAG26262.1 - 0.035 14.0 0.1 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Velvet PF11754.8 OAG26263.1 - 3.7e-61 207.3 5.0 3.7e-37 128.6 0.0 3.2 2 1 1 3 3 3 2 Velvet factor CTP_synth_N PF06418.14 OAG26265.1 - 6.8e-98 327.2 0.2 1e-97 326.6 0.2 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAG26265.1 - 6.6e-55 185.8 0.0 1.1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAG26265.1 - 2e-05 24.5 0.4 0.00024 20.9 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 RNA_capsid PF03035.14 OAG26266.1 - 0.027 14.5 1.3 0.033 14.2 1.3 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein EstA_Ig_like PF18435.1 OAG26266.1 - 0.037 14.2 0.2 0.046 13.9 0.2 1.3 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain FAD_binding_4 PF01565.23 OAG26267.1 - 9.2e-22 77.3 2.1 2.5e-21 75.9 2.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG26267.1 - 2e-05 24.6 0.1 5.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like LRR_4 PF12799.7 OAG26268.1 - 1.8e-34 117.2 22.7 1.7e-08 34.6 1.2 6.3 4 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG26268.1 - 3.3e-17 62.0 25.6 1.1e-06 28.3 2.9 5.9 2 2 4 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 OAG26268.1 - 1.4e-13 50.8 13.9 2.1e-06 27.4 1.0 3.9 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 OAG26268.1 - 0.0052 16.7 15.0 0.8 9.9 0.1 6.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 OAG26268.1 - 0.024 15.1 18.5 8.9 7.3 1.3 8.0 8 2 0 8 8 8 0 Leucine Rich Repeat SnoaL_2 PF12680.7 OAG26270.1 - 1.1e-05 26.0 0.0 1.5e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG26270.1 - 0.0044 16.8 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NIF PF03031.18 OAG26272.1 - 3.3e-54 182.9 0.1 4.8e-54 182.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acyltransferase PF01553.21 OAG26273.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3929 PF13066.6 OAG26273.1 - 0.045 13.8 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) Kinesin PF00225.23 OAG26274.1 - 5.2e-102 341.2 0.3 5.2e-102 341.2 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG26274.1 - 7.2e-58 194.8 0.5 1.8e-57 193.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding RuBisCO_large PF00016.20 OAG26274.1 - 0.0008 18.7 0.3 0.0014 17.9 0.3 1.3 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain AAA_16 PF13191.6 OAG26274.1 - 0.038 14.4 0.0 0.038 14.4 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OAG26274.1 - 5.8 7.2 8.0 0.94 9.8 0.2 3.2 2 2 1 3 3 3 0 AAA domain DUF2439 PF10382.9 OAG26275.1 - 3.4e-26 91.4 0.1 5.8e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) HNF-1_N PF04814.13 OAG26275.1 - 0.26 11.9 0.1 0.26 11.9 0.1 3.4 2 1 1 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SH3_1 PF00018.28 OAG26276.1 - 3.1e-12 45.9 0.1 5.4e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG26276.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 OAG26276.1 - 2.5e-11 43.7 4.1 3.5e-11 43.2 4.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 OAG26276.1 - 4.6e-09 35.8 0.0 8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1828 PF08861.10 OAG26276.1 - 0.038 14.3 0.1 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF1828 DUF1380 PF07128.12 OAG26276.1 - 0.097 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) THOC7 PF05615.13 OAG26276.1 - 0.28 11.5 8.5 2.8 8.3 3.8 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 OmpH PF03938.14 OAG26276.1 - 0.41 11.0 3.7 8.1 6.8 1.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 OAG26276.1 - 1.6 8.8 8.3 0.42 10.7 3.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DHHC PF01529.20 OAG26277.1 - 1.5 9.0 5.5 2.6 8.2 5.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase PAP2 PF01569.21 OAG26278.1 - 0.071 12.9 1.4 0.3 10.8 0.8 2.2 1 1 0 1 1 1 0 PAP2 superfamily LapA_dom PF06305.11 OAG26278.1 - 1.9 8.4 3.3 5.5 6.9 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PhoR PF11808.8 OAG26281.1 - 2.8 8.4 4.8 0.59 10.6 0.2 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Sugar_tr PF00083.24 OAG26283.1 - 5.1e-86 289.3 28.6 6.1e-86 289.1 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG26283.1 - 7.9e-20 71.1 30.7 1.3e-19 70.4 30.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily OppC_N PF12911.7 OAG26283.1 - 0.18 11.8 5.3 0.16 12.0 1.1 2.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C BRI3BP PF14965.6 OAG26283.1 - 1 8.9 4.8 0.25 10.9 0.2 2.0 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Fungal_trans PF04082.18 OAG26284.1 - 2.9e-09 36.4 1.1 3.5e-09 36.1 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG26284.1 - 2.2e-05 24.7 3.6 3.1e-05 24.2 1.5 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAG26284.1 - 0.0011 19.3 1.1 0.0011 19.3 1.1 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG26284.1 - 0.0016 19.1 0.7 0.0016 19.1 0.7 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_clus PF00172.18 OAG26284.1 - 0.0065 16.6 11.6 0.0065 16.6 11.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.6 OAG26284.1 - 0.057 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Cytochrome_C7 PF14522.6 OAG26284.1 - 1.2 9.2 8.9 3.3 7.8 8.9 1.8 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Glyco_hydro_31 PF01055.26 OAG26285.1 - 7.2e-113 378.1 6.7 9.9e-113 377.6 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAG26285.1 - 6.1e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 OAG26285.1 - 0.00024 21.3 2.2 0.00042 20.6 0.1 2.5 3 1 0 3 3 3 1 Galactose mutarotase-like PI3Ka PF00613.20 OAG26286.1 - 1e-55 188.0 0.1 1.6e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAG26286.1 - 1.2e-41 143.2 0.0 1.9e-38 132.7 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAG26286.1 - 1.6e-28 99.3 0.0 2.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 OAG26287.1 - 1.7e-31 108.3 0.6 3.4e-31 107.3 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAG26287.1 - 4.1e-11 42.8 0.1 4.1e-11 42.8 0.1 2.6 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE MFS_1 PF07690.16 OAG26288.1 - 2.5e-12 46.4 35.0 2.5e-12 46.4 35.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 OAG26290.1 - 0.00022 21.9 3.3 0.00044 20.9 3.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cellulase PF00150.18 OAG26292.1 - 5e-39 134.4 3.2 8.9e-39 133.6 3.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 OAG26292.1 - 1.5e-24 85.9 1.9 1.7e-23 82.5 1.1 2.8 2 1 0 2 2 2 1 Carbohydrate binding domain X2 YhhN PF07947.14 OAG26293.1 - 0.0083 15.8 0.9 0.011 15.4 0.9 1.1 1 0 0 1 1 1 1 YhhN family SecE PF00584.20 OAG26295.1 - 5.4e-16 58.2 0.1 6.2e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 OAG26296.1 - 9.8e-23 80.0 17.6 0.00024 21.8 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.6 OAG26296.1 - 0.0033 17.8 0.7 6.9 7.3 0.1 3.2 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 OAG26296.1 - 0.0089 14.6 2.0 0.24 9.9 0.0 3.4 4 0 0 4 4 4 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 OAG26296.1 - 0.022 15.0 0.0 1.3 9.4 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 OAG26296.1 - 9.3 4.2 37.1 0.085 11.0 29.2 1.4 1 1 1 2 2 2 0 DNA polymerase phi SKA2 PF16740.5 OAG26297.1 - 0.0019 18.0 4.3 1.3 8.9 1.4 4.2 5 0 0 5 5 5 1 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 OAG26297.1 - 0.11 10.5 3.5 0.17 9.8 3.5 1.2 1 0 0 1 1 1 0 Prominin DUF1043 PF06295.12 OAG26297.1 - 0.13 12.3 3.1 0.13 12.3 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Jnk-SapK_ap_N PF09744.9 OAG26297.1 - 0.25 11.6 14.7 0.25 11.6 10.9 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Filament PF00038.21 OAG26297.1 - 0.34 10.4 14.5 0.047 13.3 6.5 2.7 2 1 1 3 3 3 0 Intermediate filament protein RasGAP_C PF03836.15 OAG26297.1 - 0.45 10.7 7.2 1.2 9.3 3.3 3.1 3 0 0 3 3 3 0 RasGAP C-terminus Sec34 PF04136.15 OAG26297.1 - 0.47 10.3 4.4 2.1 8.2 0.0 2.8 2 1 0 2 2 2 0 Sec34-like family Exonuc_VII_L PF02601.15 OAG26297.1 - 0.48 9.9 8.3 0.53 9.8 4.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Med30 PF11315.8 OAG26297.1 - 0.67 10.1 4.8 3.6 7.8 3.4 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 BLOC1_2 PF10046.9 OAG26297.1 - 0.7 10.2 9.2 2 8.8 0.1 3.7 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 OAG26297.1 - 0.93 9.4 4.1 1.4 8.9 3.3 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.7 OAG26297.1 - 1.1 9.3 25.1 0.11 12.6 8.3 4.2 3 1 1 4 4 4 0 Tropomyosin like Seryl_tRNA_N PF02403.22 OAG26297.1 - 1.5 9.1 17.2 1.1 9.5 10.9 3.6 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 OAG26297.1 - 1.6 8.9 7.3 3.5 7.8 5.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 OAG26297.1 - 1.7 8.5 10.3 1.2 9.0 8.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 OAG26297.1 - 1.9 7.7 6.1 3.4 6.9 6.1 1.3 1 0 0 1 1 1 0 FAM76 protein Wtap PF17098.5 OAG26297.1 - 2.2 8.2 13.0 1.2 9.1 10.1 2.0 1 1 1 2 2 2 0 WTAP/Mum2p family V_ATPase_I PF01496.19 OAG26297.1 - 2.7 5.8 3.3 4.3 5.1 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 OAG26297.1 - 4.8 7.6 14.8 20 5.6 10.8 3.5 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Ribosomal_S5 PF00333.20 OAG26298.1 - 3.1e-27 94.3 1.0 7e-27 93.2 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAG26298.1 - 9.1e-23 79.5 0.1 1.5e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAG26298.1 - 1.4 9.5 11.2 3.4 8.3 11.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldedh PF00171.22 OAG26300.1 - 3.2e-167 556.7 0.3 3.6e-167 556.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG26300.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) AAA PF00004.29 OAG26302.1 - 4e-47 160.0 0.0 2e-41 141.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG26302.1 - 4.9e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 OAG26302.1 - 3.9e-07 30.0 0.0 1.8e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 OAG26302.1 - 1.6e-06 28.6 0.0 2.4e-05 24.8 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OAG26302.1 - 1.1e-05 25.6 0.0 4.3e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 OAG26302.1 - 0.00013 21.9 0.1 0.00039 20.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 OAG26302.1 - 0.00037 20.5 0.0 0.0012 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG26302.1 - 0.0019 18.5 0.0 0.0064 16.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 OAG26302.1 - 0.0022 18.2 0.6 0.042 14.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG26302.1 - 0.0053 16.3 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG26302.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG26302.1 - 0.013 15.7 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OAG26302.1 - 0.015 14.6 0.4 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 OAG26302.1 - 0.015 15.8 0.0 0.064 13.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 OAG26302.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG26302.1 - 0.019 15.5 0.0 0.091 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG26302.1 - 0.024 14.0 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OAG26302.1 - 0.047 12.8 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 OAG26302.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 OAG26302.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG26302.1 - 0.064 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAG26302.1 - 0.088 12.7 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAG26302.1 - 0.15 11.5 0.1 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein MRP-S32 PF10210.9 OAG26302.1 - 0.29 11.7 2.1 1 10.0 0.9 2.5 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S32 AAA_11 PF13086.6 OAG26302.1 - 0.39 10.5 0.0 0.39 10.5 0.0 3.6 4 1 0 4 4 2 0 AAA domain Git3 PF11710.8 OAG26303.1 - 3.8e-18 66.0 15.3 1.1e-17 64.5 15.3 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG26303.1 - 1.1e-07 31.9 2.6 4.9e-07 29.7 0.1 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 OAG26303.1 - 0.26 10.6 12.7 0.13 11.6 9.7 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) PGG PF13962.6 OAG26303.1 - 0.39 10.6 5.3 0.095 12.5 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function SnoaL_2 PF12680.7 OAG26304.1 - 0.018 15.7 0.0 0.026 15.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain ZZ PF00569.17 OAG26305.1 - 6.1e-14 51.6 7.8 1.2e-13 50.6 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 OAG26305.1 - 2.2e-13 48.7 3.0 0.00011 21.5 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OAG26305.1 - 5.1e-10 39.7 0.7 0.00083 19.8 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OAG26305.1 - 5.5e-10 38.4 5.8 0.0026 17.6 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OAG26305.1 - 5.7e-06 26.1 2.9 0.43 10.5 0.1 4.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAG26305.1 - 8.3e-05 21.9 2.3 1.1 8.9 0.2 3.7 3 0 0 3 3 3 2 EF hand Osmo_CC PF08946.10 OAG26305.1 - 0.13 12.5 0.2 0.4 11.0 0.2 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil adh_short_C2 PF13561.6 OAG26306.1 - 3.2e-59 200.3 1.3 3.6e-59 200.2 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG26306.1 - 7.3e-50 169.2 2.0 8.7e-50 168.9 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG26306.1 - 5.8e-16 58.9 1.2 7.7e-16 58.5 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG26306.1 - 0.00073 19.1 0.2 0.001 18.6 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3277 PF11681.8 OAG26306.1 - 0.0022 17.9 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) GDP_Man_Dehyd PF16363.5 OAG26306.1 - 0.0042 16.5 0.1 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Lipoprotein_1 PF00820.19 OAG26306.1 - 0.09 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein RmlD_sub_bind PF04321.17 OAG26306.1 - 0.17 10.9 1.0 0.34 10.0 1.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain LapA_dom PF06305.11 OAG26307.1 - 0.0069 16.2 0.3 0.0099 15.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain SARAF PF06682.12 OAG26307.1 - 0.047 13.4 0.0 0.077 12.6 0.0 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis HemY_N PF07219.13 OAG26307.1 - 0.082 13.1 0.1 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DUF3290 PF11694.8 OAG26307.1 - 0.2 11.6 0.3 0.26 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Kelch_4 PF13418.6 OAG26308.1 - 2.6e-14 53.0 0.3 3.1e-06 27.1 0.0 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG26308.1 - 3.5e-13 49.5 6.0 1.7e-10 40.9 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG26308.1 - 1.4e-12 47.0 0.0 0.00023 20.7 0.0 4.2 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 OAG26308.1 - 7.8e-10 38.5 2.5 0.0026 17.7 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OAG26308.1 - 1.1e-08 35.1 1.5 0.11 12.9 0.0 5.5 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OAG26308.1 - 1.1e-07 31.5 1.0 0.00018 21.4 0.0 4.3 4 0 0 4 4 4 1 Kelch motif BTB PF00651.31 OAG26308.1 - 0.014 15.6 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain SRP-alpha_N PF04086.13 OAG26308.1 - 0.21 11.5 1.1 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal AhpC-TSA PF00578.21 OAG26309.1 - 1.8e-30 105.4 0.0 2.5e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG26309.1 - 1.4e-12 47.5 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAG26309.1 - 4.6e-12 45.6 0.2 8.7e-12 44.7 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 OAG26310.1 - 3.5e-44 151.2 31.5 3.5e-44 151.2 31.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG26310.1 - 4.2e-09 35.4 5.4 7.4e-09 34.6 5.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG26310.1 - 0.00046 19.2 33.4 0.0038 16.1 33.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter F-box-like PF12937.7 OAG26311.1 - 3e-06 27.0 6.0 4.4e-06 26.5 1.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 OAG26311.1 - 0.00012 22.4 2.4 0.1 13.1 0.1 4.9 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.33 OAG26311.1 - 0.011 15.6 6.1 0.12 12.3 0.1 2.8 2 1 0 2 2 2 0 F-box domain LRR_6 PF13516.6 OAG26311.1 - 0.023 14.7 5.9 7.8 6.8 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat F-box_5 PF18511.1 OAG26311.1 - 0.19 11.3 0.4 2.7 7.6 0.2 2.4 2 0 0 2 2 2 0 F-box LRR_1 PF00560.33 OAG26311.1 - 0.23 12.1 4.1 6.1 7.8 0.2 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat IBR PF01485.21 OAG26312.1 - 7.7e-13 48.5 37.0 2.2e-09 37.4 5.9 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OAG26312.1 - 0.00017 21.8 9.3 0.00017 21.8 9.3 3.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 OAG26312.1 - 0.0029 17.4 8.1 0.0029 17.4 8.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.19 OAG26313.1 - 1.3e-18 67.4 0.0 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG26313.1 - 0.00015 21.9 0.3 0.00037 20.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG26313.1 - 0.00031 20.1 0.1 0.00069 19.0 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG26313.1 - 0.0035 17.0 1.5 0.0078 15.8 0.7 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG26313.1 - 0.034 14.7 1.1 1.3 9.6 0.4 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 OAG26313.1 - 0.11 12.3 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain FAD_binding_2 PF00890.24 OAG26313.1 - 0.17 10.9 1.0 0.4 9.7 0.8 1.7 2 0 0 2 2 2 0 FAD binding domain EPL1 PF10513.9 OAG26314.1 - 2.5e-32 112.4 1.4 8.2e-31 107.5 0.0 2.9 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 OAG26314.1 - 1.5e-31 108.8 9.9 1.5e-31 108.8 9.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG26314.1 - 1.4e-25 89.3 17.6 2.1e-25 88.8 8.7 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 OAG26314.1 - 1.7e-14 53.1 1.8 1.7e-14 53.1 1.8 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OAG26314.1 - 1.3e-08 34.6 9.1 1.3e-08 34.6 9.1 2.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 OAG26314.1 - 9.8 5.8 14.0 0.038 13.6 2.8 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RRM_1 PF00076.22 OAG26315.1 - 1.6e-19 69.4 0.0 2.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG26315.1 - 0.0028 17.2 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.8 OAG26316.1 - 6.7e-88 294.0 1.9 8.8e-88 293.7 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1996 PF09362.10 OAG26318.1 - 1.5e-79 267.3 7.1 1.5e-79 267.3 7.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) zf-RING_12 PF17976.1 OAG26318.1 - 0.08 13.2 0.3 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GST_N PF02798.20 OAG26321.1 - 1e-14 54.6 0.0 2.7e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG26321.1 - 9.2e-13 48.4 0.0 2.3e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG26321.1 - 3.9e-11 43.1 0.0 8.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG26321.1 - 9.9e-11 41.7 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG26321.1 - 1.9e-07 31.0 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG26321.1 - 7.1e-07 29.3 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zein-binding PF04576.15 OAG26321.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Zein-binding TFR_dimer PF04253.15 OAG26322.1 - 1.4e-23 83.3 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG26322.1 - 2.3e-23 82.9 0.0 5e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG26322.1 - 1.1e-07 31.8 0.0 2.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG26322.1 - 0.041 13.6 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 2OG-FeII_Oxy PF03171.20 OAG26323.1 - 1e-14 54.8 0.0 2.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG26323.1 - 1.3e-11 45.2 0.0 2.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Acyl-CoA_dh_1 PF00441.24 OAG26324.1 - 8.8e-44 149.3 0.7 1.5e-43 148.6 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG26324.1 - 1.5e-21 76.4 0.2 2.6e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG26324.1 - 4.6e-20 72.4 0.0 1e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 OAG26324.1 - 1.1e-18 67.1 0.2 2.1e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 OAG26324.1 - 2e-10 41.1 0.0 3.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 OAG26324.1 - 0.089 13.3 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 C6 domain Cupin_2 PF07883.11 OAG26325.1 - 1.3e-11 44.0 0.5 2.5e-11 43.1 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG26325.1 - 0.00039 20.1 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG26325.1 - 0.043 13.7 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain HutD PF05962.11 OAG26325.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.4 1 1 0 1 1 1 0 HutD Glyco_hydro_92 PF07971.12 OAG26326.1 - 1.4e-127 426.4 0.1 1.7e-127 426.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG26326.1 - 3.6e-57 194.0 3.0 5.7e-57 193.4 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain AIM5 PF17050.5 OAG26326.1 - 0.0059 17.4 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Metallophos PF00149.28 OAG26327.1 - 9.5e-35 121.0 0.1 1.5e-34 120.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG26327.1 - 7.6e-17 61.5 0.0 1.8e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FAM131 PF15010.6 OAG26327.1 - 0.026 14.4 0.2 0.043 13.7 0.2 1.3 1 0 0 1 1 1 0 Putative cell signalling Aldedh PF00171.22 OAG26328.1 - 3.9e-185 615.8 0.4 4.8e-185 615.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG26328.1 - 0.0031 17.0 0.0 0.078 12.4 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Methyltransf_PK PF05891.12 OAG26329.1 - 4e-78 261.9 0.0 4.7e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OAG26329.1 - 0.0035 18.0 0.0 0.03 15.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Radial_spoke PF04712.12 OAG26330.1 - 0.054 12.4 12.0 0.077 11.9 12.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 OAG26330.1 - 5.1 5.2 11.2 7.2 4.7 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Methyltransf_11 PF08241.12 OAG26331.1 - 0.024 15.3 0.0 0.054 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG26331.1 - 0.13 12.9 0.0 0.33 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DNA_binding_1 PF01035.20 OAG26333.1 - 1.7e-25 89.0 0.0 2e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TPR_17 PF13431.6 OAG26334.1 - 0.00046 20.4 5.1 0.26 11.8 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG26334.1 - 0.0018 17.9 0.5 2.4 7.9 0.3 3.1 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 OAG26334.1 - 0.0087 16.3 9.2 0.41 11.0 0.3 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG26334.1 - 0.11 12.4 0.1 13 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG26334.1 - 0.16 12.2 0.4 28 5.2 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG26334.1 - 0.29 11.9 2.4 12 6.8 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG26334.1 - 0.3 12.0 7.3 0.99 10.4 0.3 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG26334.1 - 1.6 9.4 8.9 0.42 11.3 0.6 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribophorin_II PF05817.14 OAG26335.1 - 1.6e-29 103.0 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II HIG_1_N PF04588.13 OAG26337.1 - 9.6e-20 70.6 0.1 1.3e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region LEA_4 PF02987.16 OAG26337.1 - 0.021 14.9 9.5 0.052 13.6 9.5 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF1746 PF08508.10 OAG26338.1 - 9.9e-38 129.0 0.1 1.3e-37 128.6 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF5586 PF17824.1 OAG26339.1 - 0.15 11.2 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF386 PF04074.12 OAG26340.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 YhcH/YjgK/YiaL Neur PF00064.18 OAG26340.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.4 1 1 0 1 1 1 0 Neuraminidase bZIP_2 PF07716.15 OAG26341.1 - 0.018 15.1 9.0 0.045 13.8 9.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper SGL PF08450.12 OAG26342.1 - 3.1e-68 230.0 0.0 3.7e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region ABC2_membrane PF01061.24 OAG26343.1 - 2.1e-39 135.1 22.8 3.4e-39 134.5 22.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG26343.1 - 1.7e-27 96.6 0.0 2.7e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OAG26343.1 - 2.1e-07 30.4 26.8 2.1e-07 30.4 26.8 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG26343.1 - 1.1e-05 25.5 0.0 0.16 11.7 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OAG26343.1 - 0.011 15.5 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG26343.1 - 0.034 13.9 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG26343.1 - 0.053 14.1 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OAG26343.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 OAG26343.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 OAG26343.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3278 PF11683.8 OAG26343.1 - 1.3 9.1 3.3 3.6 7.7 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) AAA_25 PF13481.6 OAG26343.1 - 1.9 8.0 3.5 0.82 9.2 0.4 1.9 3 0 0 3 3 3 0 AAA domain Aminotran_1_2 PF00155.21 OAG26344.1 - 7.1e-44 150.4 0.0 8.6e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG26344.1 - 1.3e-07 30.9 0.0 3.5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG26344.1 - 0.00023 19.8 0.0 0.00033 19.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAG26344.1 - 0.00049 19.5 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Alliinase_C PF04864.13 OAG26344.1 - 0.00085 18.3 0.2 0.012 14.5 0.2 2.2 1 1 0 1 1 1 1 Allinase zf-SCNM1 PF15803.5 OAG26344.1 - 0.052 13.2 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Plasmid_parti PF01672.16 OAG26344.1 - 0.12 13.0 0.1 8.5 7.1 0.0 2.6 3 0 0 3 3 3 0 Putative plasmid partition protein COX7a PF02238.15 OAG26346.1 - 0.66 10.4 3.4 2.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Biotin_lipoyl PF00364.22 OAG26347.1 - 1.8e-20 72.5 0.6 3.8e-20 71.5 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG26347.1 - 4.6e-07 30.1 0.5 1.9e-06 28.1 0.1 2.3 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAG26347.1 - 6.5e-06 25.9 0.5 0.00097 18.9 0.0 3.2 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAG26347.1 - 0.0095 16.6 0.2 0.28 11.9 0.2 2.7 1 1 0 1 1 1 1 HlyD family secretion protein DUF1631 PF07793.11 OAG26347.1 - 0.38 9.1 2.1 0.49 8.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) E1-E2_ATPase PF00122.20 OAG26348.1 - 2.2e-35 121.8 24.3 1.3e-31 109.6 0.5 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG26348.1 - 8.9e-24 84.2 9.2 8.9e-24 84.2 9.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG26348.1 - 3.2e-19 70.1 0.3 3e-18 66.9 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG26348.1 - 7.9e-19 67.5 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG26348.1 - 4.3e-16 58.4 0.0 9.5e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG26348.1 - 5.8e-05 23.0 0.1 0.00037 20.3 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 OAG26348.1 - 6 6.8 8.2 0.83 9.6 2.0 2.5 2 0 0 2 2 2 0 CoA-binding domain Na_H_Exchanger PF00999.21 OAG26349.1 - 2.4e-34 118.8 28.3 6.3e-34 117.4 28.3 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family CPP1-like PF11833.8 OAG26349.1 - 0.17 11.6 4.1 19 4.9 0.0 3.7 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fst_toxin PF13955.6 OAG26349.1 - 1.2 9.1 12.3 0.28 11.2 0.4 2.8 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system ICMT PF04140.14 OAG26350.1 - 5.6e-05 23.5 0.8 5.6e-05 23.5 0.8 2.5 1 1 2 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PHO4 PF01384.20 OAG26351.1 - 2.3e-109 365.5 16.3 2.7e-109 365.3 16.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 OAG26351.1 - 0.059 13.2 0.5 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain Caveolin PF01146.17 OAG26351.1 - 0.31 11.0 2.9 0.27 11.2 0.5 2.1 2 0 0 2 2 2 0 Caveolin Mito_carr PF00153.27 OAG26352.1 - 5.1e-71 234.7 0.6 1e-24 86.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OAG26352.1 - 2.1e-15 56.9 2.5 7.5e-07 29.5 0.4 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG26352.1 - 1.2e-14 52.7 3.6 0.00037 19.8 0.0 4.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OAG26352.1 - 5e-13 47.8 3.3 0.00031 20.4 0.0 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 OAG26352.1 - 1.5e-07 31.1 0.7 0.022 14.6 0.1 4.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG26352.1 - 5.6e-06 25.6 5.9 0.055 13.0 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAG26352.1 - 0.026 14.9 0.1 92 3.5 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Caleosin PF05042.13 OAG26352.1 - 0.073 13.0 0.3 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Caleosin related protein Serine_protease PF18405.1 OAG26352.1 - 0.21 10.7 0.6 12 5.0 0.0 3.1 2 1 1 3 3 3 0 Gammaproteobacterial serine protease zf-C2H2 PF00096.26 OAG26354.1 - 6.3e-08 32.7 12.0 0.0051 17.2 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG26354.1 - 0.00017 21.9 9.6 0.62 10.6 0.6 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG26354.1 - 0.019 15.8 10.9 0.11 13.4 1.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAG26354.1 - 0.34 11.2 9.2 0.31 11.4 1.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TMEM132D_C PF15706.5 OAG26355.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Protocadherin PF08374.11 OAG26355.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Protocadherin DUF2970 PF11174.8 OAG26355.1 - 0.077 12.9 0.8 0.19 11.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Glycophorin_A PF01102.18 OAG26355.1 - 0.12 12.6 0.3 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A Ribosomal_S8 PF00410.19 OAG26357.1 - 4.6e-15 55.7 0.0 4.7e-13 49.2 0.0 2.8 1 1 0 1 1 1 1 Ribosomal protein S8 MARVEL PF01284.23 OAG26358.1 - 0.00014 21.9 15.5 0.00021 21.4 15.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 OAG26358.1 - 0.0027 18.0 5.1 0.0043 17.3 0.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4293) TetR_C_24 PF17932.1 OAG26358.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SUR7 PF06687.12 OAG26358.1 - 0.7 9.5 13.7 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 SUR7/PalI family COX7a PF02238.15 OAG26358.1 - 0.79 10.2 3.7 7.1 7.1 0.4 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VII IMS PF00817.20 OAG26360.1 - 1.4e-40 138.7 0.4 3e-40 137.7 0.4 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAG26360.1 - 1.8e-15 57.7 0.2 3.8e-15 56.6 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG26360.1 - 0.0036 17.5 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif RGS12_us1 PF16613.5 OAG26360.1 - 0.025 14.9 0.6 0.025 14.9 0.6 2.0 2 0 0 2 2 2 0 Unstructured region of RGS12 Vps36-NZF-N PF16988.5 OAG26360.1 - 0.045 13.2 0.5 0.51 9.8 0.1 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PP_kinase PF02503.17 OAG26360.1 - 0.11 12.1 0.3 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 Polyphosphate kinase middle domain SpoIIP PF07454.11 OAG26360.1 - 0.13 11.7 3.2 1.6 8.1 0.0 2.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 OAG26362.1 - 3.6e-69 233.5 3.4 4.1e-69 233.3 3.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Bac_rhodopsin PF01036.18 OAG26363.1 - 1.4e-45 155.6 16.6 1.8e-45 155.3 16.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 OAG26363.1 - 0.13 12.5 11.3 0.89 9.9 1.6 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2178 PF09946.9 OAG26363.1 - 0.24 11.6 5.4 1.8 8.7 0.1 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DUF2516 PF10724.9 OAG26363.1 - 0.29 11.4 9.1 0.3 11.4 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF4064 PF13273.6 OAG26363.1 - 0.34 11.2 9.5 2.6 8.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 OAG26363.1 - 0.65 9.6 3.7 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MerC PF03203.14 OAG26363.1 - 2.6 8.5 9.9 5.1 7.6 5.2 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein DUF1129 PF06570.11 OAG26363.1 - 3.9 6.9 9.7 2.3 7.7 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RPEL PF02755.15 OAG26364.1 - 2.7e-30 103.1 10.3 8.4e-10 38.0 3.1 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 OAG26364.1 - 0.093 13.3 0.2 3.2 8.3 0.0 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Sugar_tr PF00083.24 OAG26365.1 - 6.3e-115 384.6 22.7 7.2e-115 384.4 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG26365.1 - 5.8e-15 55.1 26.3 5.8e-15 55.1 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 OAG26366.1 - 8.8e-143 475.7 1.3 1.4e-142 475.0 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) RVT_connect PF06815.13 OAG26366.1 - 0.09 13.0 0.6 0.21 11.9 0.6 1.6 1 0 0 1 1 1 0 Reverse transcriptase connection domain Pkinase PF00069.25 OAG26367.1 - 3.6e-75 252.7 0.0 4.3e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG26367.1 - 2.6e-36 125.2 0.0 3.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG26367.1 - 0.00012 21.2 0.0 0.00051 19.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG26367.1 - 0.0099 15.3 0.2 0.027 13.8 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG26367.1 - 0.032 14.2 1.6 0.034 14.1 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 OAG26369.1 - 1.8e-09 37.6 7.4 3e-09 36.8 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG26369.1 - 0.0037 16.3 0.2 0.025 13.6 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.16 OAG26370.1 - 8.4e-10 38.9 7.5 1.6e-09 38.0 7.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3824 PF12868.7 OAG26370.1 - 0.015 16.0 39.7 0.093 13.4 2.3 4.6 4 1 0 4 4 4 0 Domain of unknwon function (DUF3824) DUF3611 PF12263.8 OAG26370.1 - 0.025 14.5 0.9 0.053 13.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF2427 PF10348.9 OAG26370.1 - 0.12 12.2 10.0 0.014 15.1 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 OAG26370.1 - 2.9 8.0 12.4 4.8 7.3 3.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MARVEL PF01284.23 OAG26370.1 - 3.8 7.5 13.5 7.1 6.6 5.9 2.3 2 0 0 2 2 2 0 Membrane-associating domain Peptidase_U4 PF03419.13 OAG26370.1 - 8.3 5.6 5.9 13 5.0 4.6 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Spc7 PF08317.11 OAG26371.1 - 0.011 14.7 18.6 0.024 13.5 2.5 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAG26371.1 - 0.026 14.6 14.3 0.012 15.7 11.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 OAG26371.1 - 0.044 14.1 5.7 0.093 13.0 1.9 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 OAG26371.1 - 0.047 13.5 11.6 0.39 10.5 11.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 OAG26371.1 - 0.053 12.9 14.3 0.39 10.0 3.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Arm-DNA-bind_5 PF17293.2 OAG26371.1 - 0.078 13.4 7.1 0.41 11.1 0.8 2.9 2 1 1 3 3 3 0 Arm DNA-binding domain AAA_13 PF13166.6 OAG26371.1 - 0.15 10.7 8.0 0.19 10.3 8.0 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 OAG26371.1 - 0.17 11.9 1.0 1.8 8.6 1.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 OAG26371.1 - 0.38 9.8 9.9 0.94 8.5 9.7 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 OAG26371.1 - 0.48 10.8 8.6 6.9 7.0 0.7 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3552 PF12072.8 OAG26371.1 - 0.49 9.8 18.3 0.35 10.2 6.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Csm1_N PF18504.1 OAG26371.1 - 0.61 10.5 18.2 4.7 7.6 0.3 4.5 2 2 2 4 4 4 0 Csm1 N-terminal domain ATG16 PF08614.11 OAG26371.1 - 0.7 10.1 32.0 1.3 9.2 8.1 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OAG26371.1 - 0.79 10.4 12.5 0.18 12.4 2.4 3.6 2 1 0 2 2 2 0 SlyX Fez1 PF06818.15 OAG26371.1 - 1.2 9.5 20.5 1.4 9.3 14.7 2.8 2 1 0 2 2 2 0 Fez1 DUF16 PF01519.16 OAG26371.1 - 1.8 9.1 5.5 7.7 7.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 ABC_tran_CTD PF16326.5 OAG26371.1 - 2.1 8.7 28.1 0.16 12.2 0.6 4.7 2 2 2 4 4 4 0 ABC transporter C-terminal domain ADIP PF11559.8 OAG26371.1 - 2.6 8.1 13.4 1.1 9.3 6.1 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1090 PF06476.12 OAG26371.1 - 2.9 8.0 12.2 0.15 12.2 0.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) DHR10 PF18595.1 OAG26371.1 - 3.2 7.8 19.4 5.3 7.1 11.2 3.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Med30 PF11315.8 OAG26371.1 - 3.3 7.9 7.2 1.9 8.7 2.3 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 DivIC PF04977.15 OAG26371.1 - 3.4 7.5 20.0 1.6 8.6 0.3 3.7 2 1 1 3 3 3 0 Septum formation initiator DUF2968 PF11180.8 OAG26371.1 - 3.8 7.1 10.9 0.32 10.6 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MscS_porin PF12795.7 OAG26371.1 - 4.6 6.7 33.4 0.13 11.8 16.6 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Ion_trans_2 PF07885.16 OAG26374.1 - 3.6e-26 90.9 28.9 1.2e-14 54.0 7.3 3.5 3 0 0 3 3 3 3 Ion channel Deltameth_res PF16020.5 OAG26374.1 - 3.7 7.5 6.4 1 9.3 1.0 2.7 3 0 0 3 3 3 0 Deltamethrin resistance DEAD PF00270.29 OAG26375.1 - 1.7e-45 154.9 0.0 3.6e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG26375.1 - 1.2e-29 102.8 0.0 4.8e-27 94.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Abhydrolase_3 PF07859.13 OAG26375.1 - 3.5e-24 85.8 0.0 1.9e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG26375.1 - 2.4e-06 26.7 0.0 4.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family ResIII PF04851.15 OAG26375.1 - 0.00097 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAG26375.1 - 0.0064 15.3 0.0 0.39 9.4 0.0 2.6 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 40S_SA_C PF16122.5 OAG26375.1 - 0.55 11.6 3.4 7.4 8.0 0.1 2.6 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus DUF2457 PF10446.9 OAG26376.1 - 4.2e-148 494.4 30.7 4.2e-148 494.4 30.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) Glyco_transf_90 PF05686.12 OAG26377.1 - 4.7e-22 78.4 1.4 6.7e-22 77.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG26377.1 - 0.14 12.5 0.1 0.47 10.9 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 EBA-175_VI PF11556.8 OAG26379.1 - 0.12 12.7 0.6 0.22 11.9 0.3 1.5 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 HSP90 PF00183.18 OAG26381.1 - 1.8e-221 736.6 30.8 2.3e-221 736.2 30.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAG26381.1 - 4.1e-15 56.3 0.1 7.5e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG26381.1 - 1.4e-10 41.2 0.2 5.2e-10 39.3 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 OAG26381.1 - 2.2 8.3 7.1 3 7.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Glyco_hydro_88 PF07470.13 OAG26382.1 - 1.9e-87 293.6 1.8 2.2e-87 293.4 1.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 OAG26382.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 OAG26384.1 - 5.1e-30 104.6 22.6 7e-30 104.1 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2499 PF10693.9 OAG26384.1 - 0.081 13.2 2.7 0.19 12.0 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) Flavin_Reduct PF01613.18 OAG26385.1 - 4.9e-14 52.7 0.0 7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 OAG26386.1 - 2.9e-18 66.0 0.2 5.1e-18 65.2 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26386.1 - 7.9e-07 28.9 0.1 5.1e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG26386.1 - 6.7e-05 22.9 2.1 0.00021 21.2 0.1 2.4 1 1 1 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAG26386.1 - 0.025 13.6 0.0 0.063 12.3 0.0 1.6 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG26386.1 - 0.074 12.2 0.0 0.22 10.6 0.0 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 OAG26386.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OAG26386.1 - 0.16 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glyco_hydro_16 PF00722.21 OAG26388.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DNA_gyraseA_C PF03989.13 OAG26389.1 - 0.043 13.3 0.1 0.08 12.4 0.1 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller zf-ANAPC11 PF12861.7 OAG26390.1 - 5.2e-43 145.0 8.0 6.1e-43 144.8 8.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG26390.1 - 4.8e-22 78.0 11.6 7e-22 77.5 11.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG26390.1 - 3.2e-08 33.8 14.4 1.8e-07 31.4 14.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG26390.1 - 7.9e-06 25.7 12.2 2.1e-05 24.3 12.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG26390.1 - 0.00014 21.8 13.5 0.00082 19.3 7.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG26390.1 - 0.00049 19.9 8.0 0.00049 19.9 8.0 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG26390.1 - 0.005 16.7 11.5 0.46 10.4 11.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG26390.1 - 0.0062 16.5 13.9 0.033 14.1 13.9 2.1 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAG26390.1 - 0.0068 16.0 6.0 0.0068 16.0 6.0 1.9 1 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OAG26390.1 - 0.008 16.3 5.1 0.008 16.3 5.1 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 OAG26390.1 - 0.022 14.6 0.1 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Nse PF11789.8 OAG26390.1 - 0.024 14.5 6.1 0.055 13.3 6.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OAG26390.1 - 0.025 14.4 10.5 0.91 9.4 7.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OAG26390.1 - 0.029 14.7 7.2 0.029 14.7 7.2 1.6 2 1 0 2 2 1 0 RING-like domain zf-HIT PF04438.16 OAG26390.1 - 0.066 13.1 9.2 0.081 12.8 3.9 2.3 2 0 0 2 2 2 0 HIT zinc finger FANCL_C PF11793.8 OAG26390.1 - 0.095 12.9 14.0 0.73 10.1 14.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OAG26390.1 - 0.13 12.1 12.7 0.48 10.2 10.2 2.7 2 1 0 2 2 2 0 RING-like zinc finger RecR PF02132.15 OAG26390.1 - 0.92 9.1 8.9 0.61 9.7 0.3 3.1 3 0 0 3 3 3 0 RecR protein RINGv PF12906.7 OAG26390.1 - 1.8 8.8 12.4 9.7 6.4 12.4 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.7 OAG26390.1 - 3.4 7.8 12.2 6.3e+02 0.5 12.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon Rhodanese PF00581.20 OAG26391.1 - 3.3e-15 56.5 0.0 1.5e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RRN9 PF10680.9 OAG26392.1 - 2.7e-16 59.6 1.8 2.7e-16 59.6 1.8 2.7 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor CENP-B_dimeris PF09026.10 OAG26392.1 - 1.8 9.0 21.1 1.1 9.7 12.1 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Amino_oxidase PF01593.24 OAG26393.1 - 1.3e-17 64.3 0.0 5.3e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG26393.1 - 4.2e-09 36.5 0.1 9.1e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG26393.1 - 6.9e-07 28.7 1.1 1e-06 28.1 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG26393.1 - 7.7e-06 25.5 0.6 1.2e-05 24.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG26393.1 - 3.7e-05 23.5 0.7 7.2e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG26393.1 - 6.2e-05 23.5 0.2 0.00018 22.0 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG26393.1 - 9.9e-05 21.2 1.0 0.00016 20.5 1.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OAG26393.1 - 0.00012 21.5 1.9 0.00013 21.4 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG26393.1 - 0.00091 18.5 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG26393.1 - 0.0023 17.3 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG26393.1 - 0.0044 17.5 0.0 0.012 16.1 0.0 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding Thi4 PF01946.17 OAG26393.1 - 0.0079 15.5 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 OAG26393.1 - 0.055 13.1 0.5 0.1 12.2 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG26393.1 - 0.14 11.2 0.4 0.23 10.5 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAG26393.1 - 0.16 11.8 0.4 0.33 10.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos PF00149.28 OAG26394.1 - 6.1e-11 43.2 0.0 1.4e-10 42.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG26394.1 - 6.7e-10 39.4 0.0 1.4e-08 35.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain COesterase PF00135.28 OAG26396.1 - 5.5e-86 289.5 0.0 8.2e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG26396.1 - 0.017 15.0 0.2 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold S100PBPR PF15427.6 OAG26397.1 - 0.47 9.7 0.9 0.64 9.2 0.9 1.1 1 0 0 1 1 1 0 S100P-binding protein NIF3 PF01784.18 OAG26399.1 - 1.4e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) tRNA_SAD PF07973.14 OAG26400.1 - 2.4e-08 33.9 0.5 1.2e-07 31.8 0.3 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 OAG26400.1 - 0.011 14.3 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) DUF1507 PF07408.11 OAG26400.1 - 0.16 11.8 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) PilA4 PF18682.1 OAG26400.1 - 0.2 12.0 0.5 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Pilin A4 Glyco_hydro_16 PF00722.21 OAG26401.1 - 8.3e-06 25.4 0.0 2.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.6 OAG26403.1 - 9.9e-22 77.9 0.0 2.7e-21 76.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG26403.1 - 0.025 14.0 0.1 0.96 8.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 OAG26403.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family zf-C2H2 PF00096.26 OAG26404.1 - 0.00066 20.0 18.3 1.2 9.8 0.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type TOC159_MAD PF11886.8 OAG26404.1 - 0.035 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain zf-met PF12874.7 OAG26404.1 - 0.051 14.0 1.2 5.3 7.6 0.5 3.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAG26404.1 - 0.22 12.1 3.1 5.3 7.7 0.2 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAG26404.1 - 4.6 8.3 21.7 1.4 9.9 0.1 5.7 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG26404.1 - 5.2 7.5 9.5 11 6.4 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RPN7 PF10602.9 OAG26405.1 - 7.1e-47 159.3 0.9 1.1e-46 158.7 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG26405.1 - 2.3e-12 47.3 0.1 2.2e-10 41.0 0.0 2.9 2 1 1 3 3 3 1 PCI domain TPR_2 PF07719.17 OAG26405.1 - 0.00024 21.0 3.0 1 9.7 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG26405.1 - 0.0015 18.3 1.1 0.39 10.6 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG26405.1 - 0.0094 16.1 0.2 0.54 10.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 OAG26405.1 - 0.16 11.6 0.8 0.89 9.2 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain Zn_clus PF00172.18 OAG26406.1 - 2.2e-06 27.7 9.7 3.9e-06 26.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MPM1 PF17234.2 OAG26406.1 - 9.5 6.4 14.2 0.078 13.2 1.6 2.7 2 1 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PAM2 PF07145.15 OAG26407.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zinc_ribbon_5 PF13719.6 OAG26407.1 - 0.1 12.3 0.5 0.32 10.8 0.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OAG26407.1 - 0.15 13.0 7.8 3.1 8.9 1.7 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger ERM PF00769.19 OAG26407.1 - 2 8.2 28.3 98 2.6 28.3 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family YABBY PF04690.13 OAG26407.1 - 8.4 6.9 9.1 0.17 12.4 0.2 2.5 2 1 0 2 2 2 0 YABBY protein Sigma70_ECF PF07638.11 OAG26408.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor PAN_4 PF14295.6 OAG26409.1 - 0.0034 17.2 1.4 0.0078 16.1 1.4 1.7 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 OAG26409.1 - 0.015 15.1 2.2 0.045 13.6 2.2 1.8 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.11 OAG26409.1 - 0.02 15.0 0.8 0.053 13.6 0.8 1.7 1 0 0 1 1 1 0 PAN-like domain YecR PF13992.6 OAG26409.1 - 0.033 14.5 0.9 0.23 11.8 0.2 2.4 2 0 0 2 2 2 0 YecR-like lipoprotein Trypan_PARP PF05887.11 OAG26409.1 - 0.066 13.2 7.2 0.11 12.5 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPX PF03105.19 OAG26409.1 - 0.07 13.0 1.4 0.062 13.2 1.4 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 OAG26409.1 - 0.31 10.2 16.2 0.46 9.6 16.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PRCC PF10253.9 OAG26409.1 - 2.6 8.8 9.2 3.6 8.3 9.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ndc1_Nup PF09531.10 OAG26409.1 - 9.7 4.7 8.6 12 4.4 8.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_25 PF13649.6 OAG26410.1 - 5.8e-09 36.5 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG26410.1 - 3.3e-06 27.6 0.0 5.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG26410.1 - 2e-05 24.4 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG26410.1 - 2.5e-05 24.9 0.0 4.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG26410.1 - 0.003 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 OAG26411.1 - 1.2e-24 86.9 46.0 6.2e-13 48.4 22.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG26411.1 - 1.9 8.3 4.2 2 8.2 0.5 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like CDtoxinA PF03498.14 OAG26413.1 - 0.0096 15.5 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Acetyltransf_10 PF13673.7 OAG26414.1 - 3.2e-08 33.6 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG26414.1 - 2e-06 28.0 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG26414.1 - 6.5e-06 26.0 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG26414.1 - 0.0008 19.8 0.0 0.002 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG26414.1 - 0.0029 17.7 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAS_9 PF13426.7 OAG26415.1 - 2e-12 47.2 0.0 1.4e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG26415.1 - 0.0011 18.9 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold Ribosomal_L18 PF17135.4 OAG26415.1 - 0.045 13.2 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L21e PF01157.18 OAG26417.1 - 7.8e-47 157.3 4.3 1.3e-46 156.6 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Desulfoferrodox PF01880.18 OAG26417.1 - 0.11 13.1 0.2 0.17 12.5 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin S4 PF01479.25 OAG26418.1 - 2.3e-12 46.4 0.6 2.3e-12 46.4 0.6 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OAG26418.1 - 1.2e-05 26.1 0.1 2.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 OAG26418.1 - 0.039 14.1 0.3 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DeoC PF01791.9 OAG26419.1 - 3.1e-13 49.9 1.6 1.8e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 DeoC/LacD family aldolase His_biosynth PF00977.21 OAG26419.1 - 0.015 14.8 0.1 0.036 13.5 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein IlvC PF01450.19 OAG26419.1 - 0.12 12.6 0.3 0.22 11.8 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribosomal_S27e PF01667.17 OAG26420.1 - 1e-28 98.8 6.9 1.3e-28 98.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 OAG26420.1 - 1 9.4 7.2 4.4 7.4 4.5 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Ras PF00071.22 OAG26421.1 - 1.1e-54 184.4 0.0 1.3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG26421.1 - 1.7e-21 76.7 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG26421.1 - 5.5e-09 35.7 0.0 8.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG26421.1 - 0.0004 19.9 0.0 0.00071 19.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG26421.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG26421.1 - 0.0077 15.4 0.0 0.017 14.3 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG26421.1 - 0.03 14.4 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG26421.1 - 0.084 13.4 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAG26421.1 - 0.15 11.9 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PCI PF01399.27 OAG26422.1 - 5.3e-20 71.9 1.4 8.8e-20 71.2 0.5 1.9 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 OAG26422.1 - 0.0088 16.0 0.8 2 8.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_C65 PF10275.9 OAG26423.1 - 1.9e-71 240.4 0.0 2.4e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain WD40 PF00400.32 OAG26424.1 - 8.4e-09 35.9 9.3 0.0008 20.2 0.3 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG26424.1 - 0.00049 20.3 0.0 8.5 6.8 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OAG26424.1 - 0.0044 16.4 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal ATP-synt_DE PF00401.20 OAG26424.1 - 0.006 16.8 0.5 0.013 15.7 0.5 1.6 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Gryzun-like PF12742.7 OAG26424.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking GMC_oxred_N PF00732.19 OAG26426.1 - 7e-65 219.3 0.0 8.8e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG26426.1 - 7.2e-36 123.9 0.0 2e-35 122.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 OAG26426.1 - 0.0017 18.0 0.5 0.0042 16.7 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG26426.1 - 0.0026 16.9 2.5 0.018 14.1 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG26426.1 - 0.0028 16.9 1.9 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG26426.1 - 0.0032 17.7 0.4 0.0075 16.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG26426.1 - 0.0058 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAG26426.1 - 0.0059 15.7 0.4 0.01 14.9 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG26426.1 - 0.064 12.5 0.3 0.31 10.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG26426.1 - 0.069 11.8 0.7 0.38 9.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein XPA_C PF05181.12 OAG26427.1 - 3.1e-14 52.7 3.1 4.2e-06 26.6 0.4 2.5 2 0 0 2 2 2 2 XPA protein C-terminus RSN1_7TM PF02714.15 OAG26428.1 - 1.6e-77 260.5 18.8 1.6e-77 260.5 18.8 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG26428.1 - 1.3e-40 138.8 1.6 3e-40 137.5 1.6 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAG26428.1 - 2.4e-24 85.3 0.6 1.9e-23 82.5 0.1 2.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 OAG26428.1 - 1.1e-20 74.6 0.1 3e-20 73.2 0.1 1.8 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter K-box PF01486.17 OAG26428.1 - 0.62 10.3 2.8 10 6.4 0.2 2.6 2 0 0 2 2 2 0 K-box region zf-C2H2_4 PF13894.6 OAG26430.1 - 0.05 14.5 7.7 0.15 13.0 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Git3 PF11710.8 OAG26432.1 - 2.1e-23 83.2 18.6 3.4e-23 82.5 18.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG26432.1 - 2.1e-06 27.7 4.7 2.4e-06 27.5 0.2 2.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 OAG26432.1 - 0.0018 17.5 17.5 0.0037 16.4 17.6 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Peptidase_C50 PF03568.17 OAG26433.1 - 2.9e-149 497.5 0.0 9.6e-149 495.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C50 TPR_MalT PF17874.1 OAG26433.1 - 0.0022 17.4 1.5 0.0022 17.4 1.5 4.7 3 1 1 5 5 5 2 MalT-like TPR region TPR_8 PF13181.6 OAG26433.1 - 0.021 15.0 0.3 19 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat NFRKB_winged PF14465.6 OAG26433.1 - 0.15 12.3 0.8 0.98 9.6 0.5 2.7 2 0 0 2 2 2 0 NFRKB Winged Helix-like TPR_19 PF14559.6 OAG26433.1 - 0.17 12.4 5.0 0.86 10.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG26433.1 - 7.5 6.9 11.4 26 5.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAG26434.1 - 6.8e-21 74.5 0.3 1.3e-20 73.6 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26434.1 - 0.0017 18.4 11.0 0.0034 17.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rab5ip PF07019.12 OAG26434.1 - 0.051 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Miff PF05644.11 OAG26434.1 - 0.33 10.5 6.3 0.59 9.7 4.0 2.1 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff NAD_binding_8 PF13450.6 OAG26435.1 - 1.8e-12 47.3 0.4 5.8e-12 45.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG26435.1 - 2.2e-07 30.8 0.2 6.6e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG26435.1 - 3.9e-07 29.6 0.0 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG26435.1 - 1.8e-05 24.0 0.2 2.8e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG26435.1 - 0.00028 19.7 0.1 0.0057 15.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OAG26435.1 - 0.00038 19.9 0.1 0.024 13.9 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG26435.1 - 0.00038 20.5 0.0 0.0034 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG26435.1 - 0.00053 20.5 0.3 0.76 10.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG26435.1 - 0.0011 18.4 0.5 0.065 12.6 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG26435.1 - 0.0015 17.9 0.0 0.0035 16.6 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAG26435.1 - 0.0052 15.9 0.1 0.0078 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG26435.1 - 0.007 15.7 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain RE_Bsp6I PF09504.10 OAG26435.1 - 0.025 14.2 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease ApbA PF02558.16 OAG26435.1 - 0.031 13.9 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 OAG26435.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Shikimate_DH PF01488.20 OAG26435.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAG26435.1 - 0.42 9.9 0.8 0.55 9.5 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 OAG26436.1 - 6.4e-46 156.9 0.0 7.4e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF778 PF05608.12 OAG26437.1 - 0.014 15.8 5.8 0.021 15.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF2838 PF10998.8 OAG26438.1 - 3.8e-42 143.0 10.6 3.8e-42 143.0 10.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.15 OAG26438.1 - 0.035 13.7 2.7 0.052 13.1 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MFS_1 PF07690.16 OAG26439.1 - 9.8e-48 162.9 44.3 2.5e-47 161.5 43.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG26439.1 - 1.3e-12 47.3 8.6 1.3e-12 47.3 8.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter zinc_ribbon_9 PF14369.6 OAG26440.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon DUF5427 PF10310.9 OAG26440.1 - 0.56 9.1 5.0 0.79 8.6 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Peptidase_A21 PF03566.13 OAG26441.1 - 0.01 14.2 2.5 0.016 13.5 2.5 1.2 1 0 0 1 1 1 0 Peptidase family A21 CAP59_mtransfer PF11735.8 OAG26443.1 - 3.1e-86 289.0 0.0 3.9e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tenui_NCP PF04876.12 OAG26444.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein COesterase PF00135.28 OAG26445.1 - 1.5e-69 235.2 0.1 2.2e-69 234.7 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG26445.1 - 1.3e-05 25.1 0.2 0.00017 21.5 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG26445.1 - 0.0021 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG26445.1 - 0.075 11.9 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase Spc7 PF08317.11 OAG26446.1 - 3.1e-111 371.2 11.0 4.6e-111 370.6 11.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 OAG26446.1 - 2.3e-79 267.8 92.0 6.9e-67 226.5 28.8 5.5 2 1 2 4 4 4 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 OAG26446.1 - 4.1e-19 68.4 0.2 8.9e-19 67.3 0.2 1.6 1 0 0 1 1 1 1 Spc7_C2 UPF0242 PF06785.11 OAG26446.1 - 1.5 8.9 13.1 2.1 8.4 9.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3552 PF12072.8 OAG26446.1 - 1.5 8.2 14.3 1.7 8.0 1.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) FSH1 PF03959.13 OAG26447.1 - 1.3e-63 214.5 0.0 1.7e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG26447.1 - 3e-05 24.7 0.3 6.7e-05 23.6 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG26447.1 - 0.0013 18.0 0.2 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG26447.1 - 0.0064 16.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 OAG26447.1 - 0.0092 15.6 0.5 0.32 10.5 0.5 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAG26447.1 - 0.048 13.6 0.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OAG26447.1 - 0.053 13.0 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG26447.1 - 0.094 12.5 0.0 9.5 6.0 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 OAG26447.1 - 0.22 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Helo_like_N PF17111.5 OAG26449.1 - 3.2e-08 33.2 1.1 3.2e-08 33.2 1.1 2.4 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Mobilization_B PF17511.2 OAG26449.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.9 2 0 0 2 2 2 0 Mobilization protein B UbiA PF01040.18 OAG26450.1 - 1.7e-60 204.4 17.6 1.7e-60 204.4 17.6 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Ldi PF18566.1 OAG26451.1 - 7.3e-136 452.8 0.4 9.1e-136 452.5 0.4 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase TcfC PF16967.5 OAG26451.1 - 0.062 12.8 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 E-set like domain Adipogenin PF15202.6 OAG26451.1 - 0.086 12.9 0.7 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Adipogenin ApoL PF05461.11 OAG26451.1 - 0.25 10.6 0.1 0.25 10.6 0.1 1.4 2 0 0 2 2 2 0 Apolipoprotein L But2 PF09792.9 OAG26452.1 - 0.0031 17.9 0.1 0.0049 17.3 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_transf_28 PF03033.20 OAG26453.1 - 7.9e-18 64.8 0.1 3.2e-12 46.7 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG26453.1 - 4.2e-05 22.5 0.0 7.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OAG26453.1 - 0.036 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OAG26453.1 - 0.037 13.8 0.3 0.12 12.1 0.3 1.9 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Spo7_2_N PF15407.6 OAG26453.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 UIM PF02809.20 OAG26453.1 - 0.48 10.5 21.7 0.21 11.6 3.9 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif Ubiq_cyt_C_chap PF03981.12 OAG26454.1 - 2.3e-34 118.5 1.2 3.1e-34 118.1 1.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone MMR_HSR1 PF01926.23 OAG26455.1 - 5.8e-14 52.1 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG26455.1 - 0.00057 19.5 0.2 0.0026 17.3 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG26455.1 - 0.0053 16.7 0.5 0.025 14.5 0.5 2.0 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAG26455.1 - 0.011 15.9 0.2 0.1 12.7 0.1 2.2 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 OAG26455.1 - 0.017 14.2 0.3 0.031 13.3 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAG26455.1 - 0.03 14.9 1.3 0.047 14.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG26455.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 OAG26455.1 - 0.041 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 OAG26455.1 - 0.089 13.3 0.2 0.18 12.3 0.2 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OAG26455.1 - 0.1 12.9 0.1 12 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG26455.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAG26455.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OAG26455.1 - 0.3 11.2 1.7 4 7.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.18 OAG26456.1 - 1.5e-07 31.4 8.8 2.8e-07 30.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG26456.1 - 1.7e-05 24.0 0.6 3.3e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_22 PF13401.6 OAG26457.1 - 2.3e-05 24.7 0.1 0.00046 20.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 OAG26457.1 - 0.00057 20.0 0.0 0.0023 18.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAG26457.1 - 0.0022 18.1 0.2 0.057 13.5 0.2 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 OAG26457.1 - 0.0098 15.0 0.0 1.2 8.1 0.0 2.8 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 OAG26457.1 - 0.04 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OAG26457.1 - 0.064 13.6 0.3 3 8.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain DUF3245 PF11595.8 OAG26457.1 - 0.09 13.3 5.7 0.19 12.2 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) E2R135 PF11570.8 OAG26457.1 - 0.1 12.9 2.3 0.59 10.4 0.6 2.8 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 FAM104 PF15434.6 OAG26457.1 - 0.1 13.2 0.1 0.35 11.4 0.1 1.9 1 0 0 1 1 1 0 Family 104 DUF1772 PF08592.11 OAG26458.1 - 0.0094 16.3 0.8 0.017 15.4 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Ofd1_CTDD PF10637.9 OAG26458.1 - 0.027 13.8 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term LRRCT PF01463.24 OAG26458.1 - 0.13 12.9 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain adh_short_C2 PF13561.6 OAG26459.1 - 2.3e-38 132.1 5.9 1.7e-37 129.3 5.9 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG26459.1 - 7.3e-28 97.4 2.2 1.2e-27 96.7 2.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG26459.1 - 1.8e-07 31.3 0.8 4.4e-07 30.0 0.2 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG26459.1 - 0.0016 17.6 0.2 0.0024 17.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WSC PF01822.19 OAG26461.1 - 1.9e-08 34.4 9.9 1.9e-08 34.4 9.9 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 OAG26461.1 - 0.00017 20.9 1.1 0.00033 20.0 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 OAG26461.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) PTP_tm PF18861.1 OAG26461.1 - 0.042 13.8 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 OAG26461.1 - 0.13 13.1 0.0 0.3 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 OAG26462.1 - 0.001 18.9 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF111 PF01969.17 OAG26462.1 - 0.013 14.7 0.0 0.79 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF111 YokU PF14122.6 OAG26462.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin ArfGap PF01412.18 OAG26463.1 - 1e-29 103.0 0.1 2.1e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Amidase PF01425.21 OAG26466.1 - 3.1e-52 178.0 0.0 2e-50 172.1 0.0 2.2 1 1 1 2 2 2 2 Amidase Sigma54_CBD PF04963.13 OAG26466.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Vps5 PF09325.10 OAG26467.1 - 1.4e-12 47.7 7.4 1.4e-12 47.7 7.4 1.9 3 0 0 3 3 3 1 Vps5 C terminal like PX PF00787.24 OAG26467.1 - 6.4e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 OAG26467.1 - 0.013 15.6 3.6 0.013 15.6 3.6 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator GTP_EFTU PF00009.27 OAG26468.1 - 4.3e-57 192.8 0.0 7.1e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAG26468.1 - 8.4e-24 83.5 0.0 2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAG26468.1 - 1.8e-17 63.2 0.1 1.4e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG26468.1 - 6.9e-09 36.0 0.5 1.1e-07 32.1 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAG26468.1 - 1.2e-06 28.3 0.0 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV RF3_C PF16658.5 OAG26468.1 - 3.7e-05 23.5 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain CAP59_mtransfer PF11735.8 OAG26469.1 - 1.8e-67 227.5 0.0 2.3e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SHR3_chaperone PF08229.11 OAG26470.1 - 0.26 10.2 0.1 0.44 9.5 0.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 YL1 PF05764.13 OAG26472.1 - 6.9e-59 199.9 35.9 6.9e-59 199.9 35.9 2.2 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 OAG26472.1 - 2.6e-10 39.9 0.1 4.6e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain NYD-SP12_N PF15015.6 OAG26472.1 - 0.031 12.6 1.5 0.053 11.9 1.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal PUF PF00806.19 OAG26473.1 - 1.9e-24 83.9 0.0 0.00017 21.1 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 OAG26473.1 - 1.4e-12 47.2 0.0 2.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) mRNA_cap_enzyme PF01331.19 OAG26474.1 - 3.5e-46 157.5 0.0 5.7e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAG26474.1 - 8.8e-29 100.3 0.0 1.4e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAG26474.1 - 1.7e-06 27.8 0.0 4.4e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 ATP dependent DNA ligase domain Astacin PF01400.24 OAG26475.1 - 1.9e-13 50.4 6.5 9.2e-12 45.0 1.4 3.3 3 1 0 4 4 4 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 OAG26475.1 - 0.0023 18.5 0.3 0.0043 17.6 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG26475.1 - 0.01 15.5 0.5 0.018 14.7 0.5 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OAG26475.1 - 0.01 15.7 0.6 0.017 15.0 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG26475.1 - 0.012 15.8 1.6 0.017 15.3 1.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 OAG26475.1 - 0.023 13.3 0.2 0.041 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative peptidase family DUF3810 PF12725.7 OAG26475.1 - 0.16 11.3 0.4 0.25 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Apt1 PF10351.9 OAG26476.1 - 0.71 8.7 11.4 0.94 8.3 11.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 OAG26476.1 - 2 7.1 6.5 2.6 6.7 6.5 1.3 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 OAG26476.1 - 8.6 6.3 13.2 27 4.7 13.2 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Phenol_monoox PF04663.12 OAG26477.1 - 0.22 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Phenol hydroxylase conserved region adh_short PF00106.25 OAG26478.1 - 8.5e-09 35.1 0.0 3.2e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26478.1 - 7.3e-05 22.4 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG26478.1 - 0.00031 20.7 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 OAG26479.1 - 5.3e-28 98.1 0.3 1.5e-27 96.6 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG26479.1 - 1e-10 42.0 0.4 2.6e-09 37.5 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG26479.1 - 6.9e-09 35.4 0.2 0.00012 21.5 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG26479.1 - 4e-06 26.2 0.0 9.1e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAG26479.1 - 2.3e-05 23.6 0.1 0.13 11.3 0.0 2.6 2 1 1 3 3 3 2 Lycopene cyclase protein FMO-like PF00743.19 OAG26479.1 - 0.0014 17.2 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OAG26479.1 - 0.0023 17.9 1.1 1.9 8.5 0.0 4.0 3 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 OAG26479.1 - 0.0048 16.5 0.0 1.2 8.6 0.1 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG26479.1 - 0.03 13.4 0.0 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 OAG26479.1 - 0.035 13.8 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OAG26479.1 - 0.055 13.7 0.7 0.89 9.8 0.0 2.7 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG26479.1 - 0.11 11.3 0.2 3.7 6.3 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 OAG26479.1 - 0.11 13.0 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG26479.1 - 0.18 11.1 0.2 1.6 8.1 0.2 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 OAG26480.1 - 1.5e-59 202.0 44.8 1.8e-59 201.6 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG26480.1 - 7.2e-29 100.7 34.2 9.9e-29 100.2 34.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF443 PF04276.12 OAG26480.1 - 6.4 6.5 10.8 2.5 7.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF443) PalH PF08733.10 OAG26481.1 - 0.37 9.7 5.5 0.17 10.9 3.2 1.3 1 1 0 1 1 1 0 PalH/RIM21 Sec61_beta PF03911.16 OAG26482.1 - 4.4e-17 61.8 1.5 6.6e-17 61.3 1.5 1.3 1 0 0 1 1 1 1 Sec61beta family F-box-like PF12937.7 OAG26483.1 - 0.036 14.0 0.5 0.09 12.7 0.5 1.8 1 0 0 1 1 1 0 F-box-like Aldo_ket_red PF00248.21 OAG26485.1 - 1.3e-40 139.4 0.0 2.4e-40 138.6 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family PhoLip_ATPase_C PF16212.5 OAG26486.1 - 7.3e-83 278.1 18.5 7.3e-83 278.1 18.5 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG26486.1 - 1e-28 98.8 5.1 2.8e-28 97.4 5.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAG26486.1 - 2e-11 43.8 0.1 1.2e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG26486.1 - 4.1e-11 43.6 1.4 4.6e-07 30.3 0.5 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAG26486.1 - 7.3e-07 28.9 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG26486.1 - 0.0021 17.9 0.5 0.027 14.2 0.2 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box PF00646.33 OAG26487.1 - 0.0026 17.6 0.3 0.0062 16.4 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG26487.1 - 0.013 15.4 0.6 0.024 14.5 0.3 1.6 1 1 0 1 1 1 0 F-box adh_short PF00106.25 OAG26488.1 - 1.2e-20 73.8 0.0 4.5e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG26488.1 - 1.7e-13 50.7 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG26488.1 - 1.2e-08 35.1 0.0 2.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG26488.1 - 8.8e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG26488.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RasGAP PF00616.19 OAG26488.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase HAD_2 PF13419.6 OAG26489.1 - 6.8e-10 39.3 0.0 1.5e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase COesterase PF00135.28 OAG26490.1 - 4.7e-78 263.3 0.0 5.9e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG26490.1 - 6.3e-08 32.7 0.1 1.6e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold MARVEL PF01284.23 OAG26491.1 - 7.7e-23 81.1 10.3 9.1e-23 80.9 10.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain Methyltransf_31 PF13847.6 OAG26492.1 - 5.2e-30 104.2 0.0 7.2e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG26492.1 - 2e-21 76.5 0.0 3.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG26492.1 - 8.4e-20 71.2 0.0 1.6e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG26492.1 - 7.1e-17 61.7 0.0 3e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG26492.1 - 8.6e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG26492.1 - 2.3e-11 43.5 0.0 4.7e-11 42.5 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG26492.1 - 7.4e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG26492.1 - 4.1e-07 29.6 0.0 8.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAG26492.1 - 7.5e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG26492.1 - 0.00014 21.3 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 OAG26492.1 - 0.00015 21.6 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OAG26492.1 - 0.00017 21.5 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG26492.1 - 0.00045 19.9 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 OAG26492.1 - 0.00049 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAG26492.1 - 0.0032 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAG26492.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 OAG26492.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 OAG26492.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 OAG26492.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OAG26492.1 - 0.061 13.4 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.20 OAG26492.1 - 0.078 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.15 OAG26492.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 OAG26492.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Imm58 PF15581.6 OAG26492.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 58 UQ_con PF00179.26 OAG26494.1 - 3.8e-23 81.7 0.0 7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG26494.1 - 0.00029 20.7 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 UEV domain Ribosomal_L36 PF00444.18 OAG26495.1 - 6.1e-20 71.1 11.6 9.9e-20 70.5 11.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Stork_head PF10264.9 OAG26495.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain TLD PF07534.16 OAG26496.1 - 3.9e-26 91.9 0.1 1.5e-25 90.1 0.1 1.8 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 OAG26496.1 - 1.8e-18 67.3 0.2 4e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function Wound_ind PF08186.11 OAG26496.1 - 0.073 13.5 0.4 0.24 11.9 0.4 1.9 1 0 0 1 1 1 0 Wound-inducible basic protein family UQ_con PF00179.26 OAG26497.1 - 9.8e-24 83.6 0.0 1.7e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG26497.1 - 0.0068 16.3 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 UEV domain NMT_C PF02799.15 OAG26498.1 - 5.8e-88 293.9 0.0 9.2e-88 293.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAG26498.1 - 6.1e-74 247.2 0.3 1.9e-73 245.6 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAG26498.1 - 6.5e-07 29.5 0.1 5.6e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG26498.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 OAG26498.1 - 0.04 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF427) DUF997 PF06196.12 OAG26500.1 - 0.038 14.0 0.4 0.066 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF3357 PF11837.8 OAG26500.1 - 0.15 12.5 0.5 0.6 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) tRNA-synt_1b PF00579.25 OAG26503.1 - 1.9e-69 234.3 0.0 2.7e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAG26503.1 - 1.4e-30 105.6 0.2 6.3e-30 103.4 0.0 2.3 3 0 0 3 3 3 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 OAG26503.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 S4 domain Raffinose_syn PF05691.12 OAG26504.1 - 3.8e-53 180.4 3.5 1.4e-50 172.0 4.0 2.8 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 CBF PF03914.17 OAG26504.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 CBF/Mak21 family WD40 PF00400.32 OAG26505.1 - 3.9e-12 46.5 4.4 6.8e-05 23.6 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat TFIIA PF03153.13 OAG26505.1 - 0.43 10.5 32.8 0.84 9.6 32.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 OAG26505.1 - 0.53 8.8 5.3 0.72 8.3 5.3 1.1 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 OAG26505.1 - 0.61 9.7 26.0 1.1 8.8 26.0 1.5 1 0 0 1 1 1 0 Spt20 family CTP_transf_like PF01467.26 OAG26506.1 - 0.00067 19.9 0.2 0.0033 17.6 0.2 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like ATR13 PF16829.5 OAG26506.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Ribosomal_L30 PF00327.20 OAG26507.1 - 0.21 11.5 0.1 0.69 9.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e Ebola_NP PF05505.12 OAG26509.1 - 0.27 9.5 2.5 0.43 8.8 2.5 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein AltA1 PF16541.5 OAG26510.1 - 7.1e-17 62.3 0.0 9.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 FANCAA PF15146.6 OAG26513.1 - 0.034 13.3 2.5 0.35 9.9 0.5 2.3 1 1 1 2 2 2 0 Fanconi anemia-associated Rdx PF10262.9 OAG26514.1 - 2.6e-31 107.6 0.0 4.5e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Rdx family SQS_PSY PF00494.19 OAG26515.1 - 9.7e-39 133.4 0.0 1.6e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Synaptobrevin PF00957.21 OAG26515.1 - 0.023 14.5 0.1 0.93 9.3 0.0 2.5 2 0 0 2 2 2 0 Synaptobrevin DUF1765 PF08578.10 OAG26515.1 - 0.093 13.2 0.2 2.6 8.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) IF4E PF01652.18 OAG26516.1 - 1.5e-54 184.1 0.5 1.9e-54 183.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ-X PF14308.6 OAG26517.1 - 2.4e-78 262.4 8.5 2.4e-78 262.4 8.5 3.4 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAG26517.1 - 3.4e-26 91.1 0.5 3.4e-26 91.1 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain RSN1_7TM PF02714.15 OAG26518.1 - 7e-71 238.7 17.5 7e-71 238.7 17.5 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG26518.1 - 8.1e-40 136.1 2.0 8.1e-40 136.1 2.0 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG26518.1 - 1.6e-35 122.9 0.0 2.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Carb_anhydrase PF00194.21 OAG26520.1 - 3e-34 118.7 0.0 4.3e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Spt5-NGN PF03439.13 OAG26521.1 - 4e-18 65.1 0.0 7.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAG26521.1 - 1.2e-13 51.9 12.7 1.2e-13 51.9 12.7 3.8 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 OAG26521.1 - 2.5e-05 24.7 58.3 0.00023 21.7 25.2 4.6 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 OAG26521.1 - 0.0009 19.1 17.8 0.16 11.9 0.2 5.6 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 OAG26521.1 - 0.044 14.0 1.2 0.1 12.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) DUF1506 PF07405.11 OAG26521.1 - 0.085 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) ADH_zinc_N PF00107.26 OAG26522.1 - 9.9e-27 93.5 2.5 1.9e-26 92.6 2.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG26522.1 - 7.4e-12 46.5 0.1 1.2e-11 45.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG26522.1 - 4.7e-08 32.9 2.8 1.9e-07 30.9 0.0 2.8 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 OAG26522.1 - 0.053 13.3 2.2 0.12 12.2 2.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAP2 PF01569.21 OAG26523.1 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily PET117 PF15786.5 OAG26523.1 - 0.057 13.7 0.3 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial CoA_binding_3 PF13727.6 OAG26523.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Zn_clus PF00172.18 OAG26524.1 - 0.00015 21.8 12.7 0.00015 21.8 12.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG26524.1 - 0.0019 17.3 0.1 0.0033 16.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG26525.1 - 9.7e-31 107.0 68.2 1.6e-28 99.6 45.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG26525.1 - 4.1e-05 22.6 30.4 0.00069 18.6 3.3 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAG26525.1 - 0.0052 15.7 21.1 0.49 9.2 19.9 3.3 1 1 1 2 2 2 2 MFS_1 like family NTF2 PF02136.20 OAG26527.1 - 3.5e-25 88.9 0.8 6.6e-25 88.0 0.8 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAG26527.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG26527.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif FAM196 PF15265.6 OAG26527.1 - 0.19 11.2 15.4 0.33 10.4 15.4 1.3 1 0 0 1 1 1 0 FAM196 family CEP19 PF14933.6 OAG26527.1 - 4.9 7.4 7.1 0.3 11.4 0.6 2.3 3 0 0 3 3 3 0 CEP19-like protein Septin PF00735.18 OAG26528.1 - 8.1e-16 58.1 0.0 3e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG26528.1 - 2.4e-06 27.6 0.0 6.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG26528.1 - 0.0064 16.4 0.1 0.029 14.3 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAG26528.1 - 0.0076 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 OAG26528.1 - 0.016 15.3 3.3 0.34 10.9 1.0 3.7 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 OAG26528.1 - 0.045 14.3 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 OAG26528.1 - 0.051 13.1 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 OAG26528.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OAG26528.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAG26528.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 OAG26528.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 OAG26528.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 OAG26528.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SET PF00856.28 OAG26529.1 - 2.5e-06 28.0 0.0 8.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAG26529.1 - 0.013 15.5 5.9 0.013 15.5 5.9 2.1 2 0 0 2 2 2 0 MYND finger zf-C2HCIx2C PF10782.9 OAG26529.1 - 0.2 11.6 1.8 0.6 10.1 1.8 1.9 1 1 0 1 1 1 0 Zinc-finger ANAPC4_WD40 PF12894.7 OAG26530.1 - 3.5e-06 27.2 0.0 0.0051 17.1 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAG26530.1 - 0.00041 20.2 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 LisH WD40 PF00400.32 OAG26530.1 - 0.32 12.0 6.2 7.4 7.6 0.0 4.5 5 1 0 5 5 5 0 WD domain, G-beta repeat RRM_1 PF00076.22 OAG26531.1 - 2.2e-11 43.4 0.0 5e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4444 PF14563.6 OAG26531.1 - 0.24 11.1 0.8 8.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4444) Antimicrobial_2 PF08023.12 OAG26531.1 - 0.35 11.4 0.8 0.66 10.6 0.8 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide MFS_1 PF07690.16 OAG26532.1 - 1.2e-30 106.7 63.1 3.6e-25 88.7 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IpaC_SipC PF09599.10 OAG26532.1 - 0.14 11.7 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) SAP PF02037.27 OAG26533.1 - 3.6e-12 45.7 0.5 6.3e-12 45.0 0.5 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 OAG26533.1 - 1.3e-06 28.1 2.4 1.3e-06 28.1 2.4 2.3 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Totivirus_coat PF05518.11 OAG26533.1 - 3.4 5.6 9.7 5.1 5.0 9.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein ABC2_membrane PF01061.24 OAG26534.1 - 4.8e-77 258.1 59.1 1e-41 142.7 25.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG26534.1 - 4.4e-33 114.7 0.0 1.1e-15 58.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG26534.1 - 8.6e-31 105.7 11.7 2.8e-28 97.7 0.2 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 OAG26534.1 - 6.7e-12 45.2 43.1 5.5e-08 32.3 19.5 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 OAG26534.1 - 2.4e-06 28.0 0.1 0.0056 17.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 OAG26534.1 - 1.7e-05 24.5 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG26534.1 - 4.5e-05 23.7 0.1 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG26534.1 - 0.00029 20.8 0.0 0.00094 19.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OAG26534.1 - 0.00037 20.4 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OAG26534.1 - 0.0084 16.7 0.0 0.35 11.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 OAG26534.1 - 0.0095 15.7 0.2 0.25 11.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG26534.1 - 0.017 15.2 0.1 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG26534.1 - 0.017 15.3 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG26534.1 - 0.026 14.8 0.8 0.54 10.5 0.2 2.8 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAG26534.1 - 0.029 14.3 0.0 10 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Herpes_glycoH_C PF17488.2 OAG26534.1 - 0.048 13.4 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 1 0 Herpesvirus glycoprotein H C-terminal domain AAA_30 PF13604.6 OAG26534.1 - 0.064 13.0 0.1 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG26534.1 - 0.087 11.9 0.0 14 4.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 OAG26534.1 - 0.096 12.3 0.4 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 OAG26534.1 - 0.12 12.1 0.1 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 OAG26534.1 - 0.13 11.7 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ESSS PF10183.9 OAG26534.1 - 0.17 12.1 0.2 0.67 10.2 0.2 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA_23 PF13476.6 OAG26534.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 OAG26534.1 - 1.4 7.4 2.4 10 4.6 0.0 2.9 4 0 0 4 4 4 0 AAA domain Zn_clus PF00172.18 OAG26535.1 - 1.3e-06 28.5 9.5 1.8e-06 28.0 9.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.18 OAG26535.1 - 0.017 15.0 1.4 0.037 14.0 1.4 1.6 1 0 0 1 1 1 0 Fungal cellulose binding domain Integrase_H2C2 PF17921.1 OAG26535.1 - 0.093 12.9 0.8 8.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain Fungal_trans PF04082.18 OAG26536.1 - 0.015 14.3 2.9 0.32 10.0 0.3 3.1 2 2 0 2 2 2 0 Fungal specific transcription factor domain Mur_ligase_M PF08245.12 OAG26537.1 - 1.1e-06 28.8 2.6 8.7e-06 25.9 1.2 2.9 2 1 0 2 2 2 1 Mur ligase middle domain Zip PF02535.22 OAG26538.1 - 5.5e-57 193.5 1.6 8.1e-57 192.9 1.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.12 OAG26538.1 - 0.034 14.1 0.0 0.15 12.0 0.0 2.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1282 PF06930.12 OAG26538.1 - 0.24 11.2 4.1 0.079 12.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Frtz PF11768.8 OAG26539.1 - 0.18 10.1 0.1 0.23 9.7 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Pescadillo_N PF06732.11 OAG26540.1 - 1.9e-124 414.6 0.0 1.9e-124 414.6 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAG26540.1 - 8e-05 23.0 0.0 0.00034 21.0 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG26540.1 - 0.0019 18.5 0.0 0.0074 16.6 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAG26540.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 OAG26541.1 - 2.8e-121 405.2 27.5 3.2e-121 405.0 27.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 OAG26541.1 - 0.31 10.7 7.3 1.2 8.8 7.3 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pox_Ag35 PF03286.14 OAG26542.1 - 0.019 14.8 0.4 0.023 14.5 0.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ORC6 PF05460.13 OAG26542.1 - 0.022 14.1 3.5 0.026 13.8 3.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MutS_V PF00488.21 OAG26543.1 - 5.1e-67 225.6 0.1 1.1e-66 224.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG26543.1 - 2e-42 145.6 0.2 4.3e-42 144.5 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG26543.1 - 1.6e-31 108.9 0.2 1.5e-30 105.7 0.1 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAG26543.1 - 8.2e-13 48.8 0.0 3.5e-12 46.8 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG26543.1 - 1e-11 45.0 0.4 2.2e-11 44.0 0.4 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 OAG26543.1 - 0.022 15.2 0.1 0.022 15.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG26543.1 - 0.038 13.7 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAG26543.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OAG26543.1 - 0.2 11.4 0.2 0.59 9.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SPT6_acidic PF14632.6 OAG26543.1 - 6.5 7.4 12.7 3.8 8.1 7.6 2.7 1 1 1 2 2 2 0 Acidic N-terminal SPT6 PCI PF01399.27 OAG26544.1 - 3.2e-21 75.8 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAG26544.1 - 7.6e-16 57.9 1.0 7.6e-16 57.9 1.0 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Trehalose_PPase PF02358.16 OAG26544.1 - 0.023 13.8 1.5 0.3 10.2 0.0 2.8 3 0 0 3 3 3 0 Trehalose-phosphatase PSDC PF12588.8 OAG26545.1 - 4.5e-63 211.4 0.0 7.6e-63 210.7 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAG26545.1 - 7e-36 123.7 0.0 2.3e-35 122.0 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 OAG26545.1 - 0.036 14.0 0.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 OAG26545.1 - 0.11 12.7 0.1 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 OAG26545.1 - 0.18 11.6 1.3 1.1 9.1 0.6 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like HET PF06985.11 OAG26546.1 - 2.5e-53 180.4 5.7 9.3e-27 94.2 0.0 3.5 2 1 1 3 3 3 3 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 OAG26547.1 - 1.5e-31 109.8 1.4 1.9e-31 109.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG26547.1 - 0.019 14.6 0.6 0.028 14.0 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_130 PF04041.13 OAG26547.1 - 0.052 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase Kelch_1 PF01344.25 OAG26548.1 - 1.6e-28 98.0 21.7 3.7e-07 29.6 0.2 6.4 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 OAG26548.1 - 1.6e-18 66.3 14.8 7.1e-05 23.0 0.0 7.2 6 1 1 7 7 7 5 Kelch motif Kelch_5 PF13854.6 OAG26548.1 - 1.2e-15 57.0 5.6 0.00097 19.1 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAG26548.1 - 3.1e-13 49.7 13.2 0.0037 17.5 0.1 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG26548.1 - 3.2e-13 49.1 12.6 0.04 13.9 0.9 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OAG26548.1 - 2.9e-08 33.6 24.0 0.0067 16.4 0.1 6.9 7 2 0 7 7 7 3 Galactose oxidase, central domain RCDG1 PF15725.5 OAG26548.1 - 0.53 10.8 4.0 1.1 9.8 4.0 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Abhydrolase_1 PF00561.20 OAG26549.1 - 1.4e-10 41.2 0.0 2.4e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG26549.1 - 5e-10 40.4 0.7 6.5e-10 40.0 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG26549.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Glyco_hydro_47 PF01532.20 OAG26550.1 - 3.2e-178 593.3 0.0 3.7e-178 593.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Flag1_repress PF03614.13 OAG26552.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF3500 PF12006.8 OAG26553.1 - 2.4e-106 355.6 0.0 2.9e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) UPF0181 PF03701.14 OAG26553.1 - 0.091 12.4 0.6 0.21 11.3 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) DUF4177 PF13783.6 OAG26553.1 - 0.14 12.5 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) FAD_binding_3 PF01494.19 OAG26554.1 - 2.1e-17 63.4 0.5 1.8e-16 60.4 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG26554.1 - 1.7e-07 30.8 0.6 7.8e-05 22.0 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG26554.1 - 4.4e-07 30.0 0.2 1.3e-06 28.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG26554.1 - 4.6e-07 29.8 2.8 0.0017 18.0 1.7 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG26554.1 - 6.7e-05 22.1 2.8 0.00011 21.4 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.21 OAG26554.1 - 0.0037 16.7 0.1 0.0062 15.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 OAG26554.1 - 0.0073 16.8 0.4 0.057 14.0 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG26554.1 - 0.01 15.0 0.8 0.014 14.5 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG26554.1 - 0.012 14.9 0.3 0.02 14.1 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG26554.1 - 0.029 13.6 0.6 0.044 13.0 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG26554.1 - 0.036 13.4 0.2 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG26554.1 - 0.042 12.7 0.3 0.058 12.2 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 OAG26554.1 - 0.047 12.4 1.2 0.17 10.5 1.1 1.8 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 OAG26554.1 - 0.1 11.4 0.6 0.18 10.5 0.6 1.4 1 0 0 1 1 1 0 MCRA family F420_oxidored PF03807.17 OAG26554.1 - 2.9 8.5 4.7 5 7.8 1.8 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 OAG26555.1 - 2.5e-39 135.2 26.0 4.1e-39 134.5 26.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG26555.1 - 1.4e-08 34.0 7.4 1.4e-08 34.0 7.4 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Glyco_hydro_47 PF01532.20 OAG26556.1 - 4.2e-163 543.5 0.0 4.8e-163 543.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GPI-anchored PF10342.9 OAG26557.1 - 0.0043 17.8 4.2 0.0077 17.0 0.1 2.9 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin15 PF15672.5 OAG26557.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 MGC-24 PF05283.11 OAG26557.1 - 0.029 14.8 0.2 0.068 13.6 0.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Yip1 PF04893.17 OAG26557.1 - 1.4 8.6 7.0 0.89 9.2 3.7 2.1 2 1 0 2 2 2 0 Yip1 domain MaoC_dehydratas PF01575.19 OAG26558.1 - 2.3e-08 33.6 0.0 3.5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain TPR_14 PF13428.6 OAG26559.1 - 0.015 16.1 0.1 0.15 13.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG26559.1 - 0.099 13.3 0.0 0.44 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG26559.1 - 0.19 12.4 0.3 0.68 10.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 OAG26560.1 - 1.8e-41 142.3 0.0 1.9e-40 138.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG26560.1 - 3.7e-36 124.4 0.1 1.1e-34 119.6 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG26560.1 - 1.1e-06 28.7 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG26560.1 - 0.17 11.4 0.0 0.24 10.8 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sec7 PF01369.20 OAG26562.1 - 1.3e-32 113.0 0.0 2.1e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 OAG26562.1 - 4e-06 27.2 0.1 8.7e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAG26562.1 - 8.8e-05 23.0 0.1 0.0002 21.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.24 OAG26563.1 - 2.9e-76 257.0 0.0 4e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Malate_synthase PF01274.22 OAG26563.1 - 0.076 11.3 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Malate synthase DUF155 PF02582.14 OAG26564.1 - 7.7e-52 175.9 1.1 1.2e-51 175.3 1.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 OAG26564.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 PI3_PI4_kinase PF00454.27 OAG26565.1 - 2e-34 119.5 0.0 1.2e-33 117.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 OAG26565.1 - 5.8e-20 71.0 0.1 1.2e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 OAG26565.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Cwf_Cwc_15 PF04889.12 OAG26567.1 - 1.8e-83 280.1 25.6 2.1e-83 279.9 25.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF4692 PF15763.5 OAG26567.1 - 0.17 12.3 5.0 0.35 11.3 5.0 1.4 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CDC45 PF02724.14 OAG26567.1 - 3.1 6.0 19.2 3.4 5.8 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 OAG26567.1 - 3.2 6.6 6.6 3.6 6.4 6.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNase_PH PF01138.21 OAG26568.1 - 8.9e-21 74.8 0.0 1.4e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG26568.1 - 4.9e-11 42.5 0.0 9.4e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF4336 PF14234.6 OAG26569.1 - 1.3e-17 64.0 0.0 4.7e-13 49.0 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) SARAF PF06682.12 OAG26570.1 - 0.014 15.0 0.2 0.43 10.2 0.0 2.3 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis OATP PF03137.20 OAG26570.1 - 0.018 13.4 0.0 0.037 12.3 0.0 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 OAG26570.1 - 0.019 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier Baculo_11_kDa PF06143.11 OAG26570.1 - 0.02 14.5 0.0 0.97 9.1 0.1 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family RIC3 PF15361.6 OAG26570.1 - 0.021 15.3 0.6 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FAM176 PF14851.6 OAG26570.1 - 0.029 14.0 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 OAG26570.1 - 0.097 12.4 0.2 0.78 9.4 0.1 2.0 2 0 0 2 2 2 0 Connexin OAD_gamma PF04277.13 OAG26570.1 - 0.14 12.7 0.1 1 10.0 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CLN3 PF02487.17 OAG26570.1 - 0.15 11.0 0.1 0.24 10.4 0.1 1.4 1 1 0 1 1 1 0 CLN3 protein CENP-B_dimeris PF09026.10 OAG26570.1 - 1.4 9.3 5.5 1.9 9.0 4.6 1.7 1 1 0 1 1 1 0 Centromere protein B dimerisation domain DUF4637 PF15470.6 OAG26570.1 - 3.5 7.3 6.9 6.3 6.5 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_B_thumb PF14791.6 OAG26571.1 - 2.6e-21 75.5 0.0 6.8e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 OAG26571.1 - 3.1e-20 72.5 0.1 8.5e-20 71.1 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OAG26571.1 - 2.2e-17 62.6 0.5 6.9e-17 61.0 0.5 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAG26571.1 - 3.2e-06 27.4 0.0 1.9e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAG26571.1 - 0.0025 18.2 0.0 0.007 16.8 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAG26571.1 - 0.0066 17.0 0.0 0.3 11.7 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 OAG26571.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Autophagy_N PF03986.13 OAG26573.1 - 7.5e-44 149.0 0.3 1.2e-43 148.3 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 OAG26573.1 - 5.7e-16 57.7 0.6 9.9e-16 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 OAG26573.1 - 8.6e-15 55.1 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fungal_trans PF04082.18 OAG26574.1 - 1.2e-12 47.4 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26574.1 - 2.5e-07 30.7 15.1 5.4e-07 29.6 15.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AtuA PF07287.11 OAG26575.1 - 1.6e-129 431.7 0.1 1.9e-129 431.4 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 OAG26576.1 - 2e-34 119.1 30.7 2.1e-34 119.0 28.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PHF5 PF03660.14 OAG26577.1 - 2.1e-51 172.5 10.5 2.4e-51 172.3 10.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAG26577.1 - 0.39 8.5 7.3 0.37 8.6 6.8 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 OAG26577.1 - 2.9 8.0 16.5 5.5 7.1 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 OAG26578.1 - 2.9e-29 101.7 20.6 2.9e-29 101.7 20.6 2.2 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 OAG26579.1 - 1.9e-27 96.5 0.7 2.6e-26 92.8 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG26579.1 - 1.1e-12 49.0 0.0 1.6e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG26579.1 - 1.1e-11 44.4 0.0 3.3e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAG26579.1 - 0.0054 16.5 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family ADH_N PF08240.12 OAG26580.1 - 8.4e-27 93.2 0.9 1.9e-26 92.0 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG26580.1 - 9.9e-16 57.9 1.6 2.6e-15 56.6 1.6 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG26580.1 - 2.8e-08 33.5 0.2 0.00087 18.8 0.1 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG26580.1 - 0.019 14.3 1.0 0.035 13.4 1.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG26580.1 - 0.021 15.9 0.0 0.052 14.6 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG26580.1 - 0.036 13.7 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF281 PF03436.13 OAG26580.1 - 0.051 14.0 0.4 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF281) MitMem_reg PF13012.6 OAG26581.1 - 2.9e-10 40.6 0.0 7.5e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG26581.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease LRV_FeS PF05484.11 OAG26582.1 - 0.51 10.4 3.5 0.94 9.5 0.2 2.3 2 0 0 2 2 2 0 LRV protein FeS4 cluster FMO-like PF00743.19 OAG26585.1 - 3.1e-20 72.1 0.0 5.7e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG26585.1 - 4.7e-15 55.6 0.3 1.4e-11 44.2 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG26585.1 - 5e-12 45.6 0.1 3e-08 33.2 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG26585.1 - 4.5e-09 36.0 0.0 3.5e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG26585.1 - 3.2e-07 30.2 0.0 1.8e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG26585.1 - 5.6e-07 29.7 0.0 1.4e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG26585.1 - 1.8e-05 24.8 0.0 0.003 17.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG26585.1 - 0.0002 20.8 0.0 0.021 14.1 0.0 2.9 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG26585.1 - 0.00098 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 OAG26585.1 - 0.0014 18.7 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG26585.1 - 0.0033 16.7 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG26585.1 - 0.018 14.3 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DUF3445 PF11927.8 OAG26586.1 - 1.9e-74 250.1 0.0 2.8e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NmrA PF05368.13 OAG26587.1 - 5e-32 111.3 0.0 7.7e-32 110.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG26587.1 - 2.3e-11 43.9 0.1 3.3e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OAG26587.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 OAG26587.1 - 0.017 14.6 0.1 7.1 6.0 0.4 2.1 1 1 1 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG26587.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mrr_N PF14338.6 OAG26588.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Mrr N-terminal domain RF-1 PF00472.20 OAG26588.1 - 0.094 12.7 0.3 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 RF-1 domain UIM PF02809.20 OAG26588.1 - 3 8.0 8.0 2.3 8.3 0.8 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Glyco_hydro_61 PF03443.14 OAG26590.1 - 1.7e-60 204.5 0.1 2.1e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrolase_4 PF12146.8 OAG26591.1 - 4e-17 62.3 0.0 2.4e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG26591.1 - 2.2e-13 50.4 0.1 5.2e-13 49.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG26591.1 - 5.3e-12 46.8 0.2 5.3e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OAG26591.1 - 0.026 14.3 0.1 1 9.1 0.0 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family DLH PF01738.18 OAG26591.1 - 0.072 12.6 0.0 3.8 7.0 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 OAG26591.1 - 0.13 12.2 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAP2 PF01569.21 OAG26592.1 - 3.3e-27 94.9 0.4 3.3e-27 94.9 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAG26592.1 - 0.016 14.9 1.0 0.016 14.9 1.0 2.1 2 1 0 2 2 2 0 PAP2 superfamily PQ-loop PF04193.14 OAG26593.1 - 1.5e-23 82.3 6.0 2.5e-13 49.6 2.0 2.5 2 0 0 2 2 2 2 PQ loop repeat ERG4_ERG24 PF01222.17 OAG26594.1 - 3.8e-134 447.7 24.3 4.5e-134 447.5 24.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family IBR PF01485.21 OAG26595.1 - 1.4e-24 86.1 33.8 3.3e-13 49.7 2.1 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OAG26595.1 - 0.0057 17.0 2.2 0.0057 17.0 2.2 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OAG26595.1 - 0.084 12.6 6.6 1.6 8.5 0.5 3.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RAG1 PF10426.9 OAG26595.1 - 0.12 12.5 4.2 24 5.2 0.2 3.8 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain FAA_hydrolase PF01557.18 OAG26596.1 - 6.3e-51 173.1 0.0 8.8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG26596.1 - 1.9e-19 69.8 0.0 5.4e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.11 OAG26597.1 - 6.3e-09 35.4 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG26597.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAG26597.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin PepX_C PF08530.10 OAG26598.1 - 1.2e-42 146.3 0.1 1.8e-42 145.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 OAG26598.1 - 7.5e-40 137.2 0.4 1.1e-39 136.7 0.4 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LigB PF02900.18 OAG26599.1 - 2.3e-10 40.0 0.0 3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.18 OAG26600.1 - 2.9e-13 49.5 3.8 5.8e-13 48.5 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG26600.1 - 3.5e-07 30.3 14.2 0.00012 22.4 1.4 3.0 3 0 0 3 3 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 OAG26600.1 - 1.3e-05 25.3 12.6 1.3e-05 25.3 12.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.6 OAG26600.1 - 0.0001 22.2 1.3 0.66 10.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG26600.1 - 0.0032 18.2 0.1 0.0032 18.2 0.1 3.5 4 0 0 4 4 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG26600.1 - 0.0045 17.2 0.5 0.63 10.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG26600.1 - 0.009 16.4 4.6 0.3 11.6 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG26600.1 - 0.019 14.9 0.6 0.019 14.9 0.6 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 OAG26600.1 - 0.25 12.0 2.8 1.4 9.6 0.0 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 OAG26600.1 - 1 9.2 4.4 0.44 10.3 1.2 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG26600.1 - 7.3 7.0 10.3 1.2 9.5 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Herpes_gp2 PF05955.11 OAG26600.1 - 9.6 5.7 6.3 2.4 7.6 2.3 1.9 1 1 1 2 2 2 0 Equine herpesvirus glycoprotein gp2 MFS_1 PF07690.16 OAG26601.1 - 8e-28 97.4 27.6 8e-28 97.4 27.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG26601.1 - 6.7e-12 45.0 5.1 6.7e-12 45.0 5.1 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG26601.1 - 8.5e-07 27.8 4.1 1.5e-06 26.9 4.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 OAG26601.1 - 0.062 12.9 2.6 0.8 9.3 2.5 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Rick_17kDa_Anti PF05433.15 OAG26601.1 - 2.6 8.0 7.2 6.8 6.6 1.0 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Aldedh PF00171.22 OAG26602.1 - 3.5e-13 48.9 0.0 1.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family SATase_N PF06426.14 OAG26602.1 - 1.3 9.4 4.1 20 5.6 0.0 2.9 3 0 0 3 3 3 0 Serine acetyltransferase, N-terminal FAD_binding_3 PF01494.19 OAG26603.1 - 2.4e-20 73.1 0.0 6.3e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 OAG26603.1 - 7.4e-14 51.9 0.0 7.7e-13 48.5 0.0 2.2 2 1 0 2 2 2 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 OAG26603.1 - 1.8e-09 37.3 0.1 4.2e-09 36.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG26603.1 - 1.6e-07 31.3 0.8 9.9e-05 22.1 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG26603.1 - 1.2e-06 28.6 0.6 1.5e-05 25.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG26603.1 - 0.00024 20.3 0.4 0.00044 19.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAG26603.1 - 0.00064 19.1 0.2 0.16 11.2 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG26603.1 - 0.0065 17.0 0.1 0.023 15.2 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF2530 PF10745.9 OAG26603.1 - 0.009 16.2 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) GIDA PF01134.22 OAG26603.1 - 0.0093 15.1 0.2 0.072 12.2 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG26603.1 - 0.025 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 OAG26603.1 - 0.026 13.3 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 OAG26603.1 - 0.041 12.9 0.2 0.63 9.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG26603.1 - 0.052 12.8 1.4 0.14 11.4 0.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG26603.1 - 0.052 12.2 0.4 0.1 11.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAG26603.1 - 0.19 10.9 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HTH_Tnp_1 PF01527.20 OAG26604.1 - 0.0093 16.3 1.1 0.033 14.5 0.6 2.2 2 0 0 2 2 2 1 Transposase DUF416 PF04222.12 OAG26604.1 - 0.0096 15.4 0.6 1.7 8.0 0.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF416) HTH_23 PF13384.6 OAG26604.1 - 0.033 14.0 0.5 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF3456 PF11938.8 OAG26604.1 - 0.098 13.2 1.5 0.12 12.9 0.4 1.6 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP DUF2894 PF11445.8 OAG26604.1 - 0.27 11.7 4.2 0.089 13.3 0.9 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) Perilipin PF03036.16 OAG26604.1 - 0.27 10.2 3.9 0.11 11.5 0.5 1.9 2 0 0 2 2 2 0 Perilipin family DUF1043 PF06295.12 OAG26604.1 - 0.6 10.1 4.1 1.2 9.2 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) EF-hand_6 PF13405.6 OAG26607.1 - 8.4e-12 44.0 0.4 1.7e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAG26607.1 - 5.6e-10 39.5 4.1 1.2e-07 32.0 0.2 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG26607.1 - 3.6e-09 35.5 2.0 0.00012 21.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAG26607.1 - 1.6e-06 27.3 3.4 0.00027 20.3 0.7 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OAG26607.1 - 1.5e-05 24.8 2.3 0.021 14.7 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 OAG26607.1 - 2.7e-05 24.4 0.0 0.41 11.0 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain Afi1 PF07792.12 OAG26608.1 - 1.1e-45 155.4 2.4 1.4e-45 155.0 0.8 2.1 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 OAG26608.1 - 1.2e-36 125.1 0.0 3.4e-36 123.7 0.0 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 OAG26608.1 - 2.1e-07 30.0 0.0 0.086 11.5 0.0 4.2 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 OAG26608.1 - 0.0078 15.8 0.1 0.05 13.2 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.12 OAG26608.1 - 0.081 12.7 7.3 0.18 11.6 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) RXT2_N PF08595.11 OAG26608.1 - 0.6 10.1 4.8 2.1 8.4 4.8 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal CSRNP_N PF16019.5 OAG26608.1 - 3 7.7 5.2 0.82 9.5 0.8 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Nucleo_P87 PF07267.11 OAG26608.1 - 7.4 5.3 6.2 12 4.6 6.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AT_hook PF02178.19 OAG26609.1 - 0.084 12.8 0.3 0.084 12.8 0.3 3.4 3 0 0 3 3 3 0 AT hook motif DUF3336 PF11815.8 OAG26610.1 - 8.6e-31 106.5 0.1 1.4e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG26610.1 - 2.6e-21 76.7 0.0 6.9e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PLC-beta_C PF08703.10 OAG26614.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 PLC-beta C terminal MFS_1 PF07690.16 OAG26615.1 - 8.2e-26 90.7 21.8 8.2e-26 90.7 21.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG26615.1 - 1.3e-06 27.1 0.8 2.3e-06 26.3 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4271 PF14093.6 OAG26615.1 - 5.9 6.7 9.0 1.8 8.4 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) ABC2_membrane_3 PF12698.7 OAG26615.1 - 6.6 5.7 10.0 23 3.9 10.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein NIBRIN_BRCT_II PF16508.5 OAG26616.1 - 2.4e-27 95.6 0.0 2.3e-26 92.4 0.0 2.6 3 0 0 3 3 3 1 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 OAG26616.1 - 0.0068 16.3 0.7 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain FHA PF00498.26 OAG26616.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 FHA domain DUF1748 PF08520.10 OAG26617.1 - 7.1e-30 102.7 0.0 8.6e-30 102.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 OAG26618.1 - 4.1e-173 575.1 4.0 5e-173 574.8 4.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAG26618.1 - 1.3e-38 131.8 0.0 9e-38 129.1 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAG26618.1 - 0.0011 18.1 0.3 0.003 16.7 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAG26618.1 - 0.06 12.3 0.0 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain mRNA_triPase PF02940.15 OAG26619.1 - 2.6e-47 161.4 0.5 3.4e-47 161.0 0.5 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF1444 PF07285.11 OAG26619.1 - 0.02 14.5 0.3 0.031 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) RPN2_C PF18004.1 OAG26620.1 - 1.9e-54 183.9 7.3 1.9e-54 183.9 7.3 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OAG26620.1 - 3.9e-38 128.0 23.3 1.7e-08 34.4 0.0 8.9 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG26620.1 - 1.9e-20 73.0 1.5 6.4e-15 55.3 0.0 4.8 3 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 OAG26620.1 - 2.4e-07 31.1 0.1 0.00043 20.7 0.0 4.9 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.22 OAG26620.1 - 0.0002 21.3 3.6 4 7.9 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat ANAPC3 PF12895.7 OAG26620.1 - 0.036 14.3 0.7 9.7 6.5 0.1 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Cnd1 PF12717.7 OAG26620.1 - 0.13 12.3 2.3 2.2 8.3 0.1 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 OAG26620.1 - 0.19 12.3 1.6 60 4.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 OAG26620.1 - 2.4 9.1 4.7 14 6.7 0.0 4.3 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Sugar_tr PF00083.24 OAG26621.1 - 1.2e-82 278.2 16.5 1.5e-82 277.8 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG26621.1 - 5.5e-32 111.1 18.8 1.3e-31 109.9 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_kinase PF00696.28 OAG26621.1 - 0.003 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family MFS_1_like PF12832.7 OAG26621.1 - 0.012 14.5 8.7 0.036 12.9 2.4 2.3 2 1 0 2 2 2 0 MFS_1 like family DUF3792 PF12670.7 OAG26621.1 - 1.5 9.0 14.1 0.046 13.9 4.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) OATP PF03137.20 OAG26621.1 - 3 6.0 14.4 0.011 14.1 1.9 2.9 2 2 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 OAG26622.1 - 1.5e-07 31.9 3.2 2.2 9.3 0.0 7.4 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG26622.1 - 3.3e-06 27.3 0.8 0.47 10.8 0.0 6.3 4 3 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAG26622.1 - 0.002 17.8 0.0 0.066 12.8 0.0 3.1 2 1 1 3 3 3 1 PQQ-like domain Cyclin_N PF00134.23 OAG26624.1 - 7.8e-39 132.3 0.4 1.4e-38 131.5 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG26624.1 - 1.1e-10 41.7 0.3 2.8e-10 40.3 0.3 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain CcdA PF07362.12 OAG26624.1 - 3 8.3 4.3 33 5.0 1.5 2.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA MFS_1 PF07690.16 OAG26625.1 - 7.4e-10 38.3 29.6 7.4e-10 38.3 29.6 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Cyt-b5 PF00173.28 OAG26626.1 - 2.1e-16 59.8 0.0 3.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAPRTase PF04095.16 OAG26627.1 - 1.6e-54 185.0 1.3 2.4e-29 102.6 0.4 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAG26627.1 - 3.7e-35 121.0 0.1 5.9e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 OAG26628.1 - 1.9e-18 66.9 3.1 1.9e-18 66.9 3.1 1.9 2 1 0 2 2 1 1 Syntaxin SNARE PF05739.19 OAG26628.1 - 9.2e-10 38.4 1.8 9.2e-10 38.4 1.8 2.4 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 OAG26628.1 - 2e-05 24.4 0.4 2.9e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 ApoLp-III PF07464.11 OAG26628.1 - 0.0018 18.4 2.2 0.4 10.8 3.1 2.6 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) DUF4094 PF13334.6 OAG26628.1 - 0.019 15.4 0.0 0.86 10.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.9 OAG26628.1 - 0.02 15.2 2.1 0.24 11.7 0.7 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPW8 PF05659.11 OAG26628.1 - 0.021 14.5 0.5 0.11 12.1 0.4 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tweety PF04906.13 OAG26628.1 - 0.021 13.5 2.4 0.037 12.7 2.4 1.3 1 0 0 1 1 1 0 Tweety DUF1664 PF07889.12 OAG26628.1 - 0.026 14.6 2.9 1.6 8.8 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2207 PF09972.9 OAG26628.1 - 0.047 12.4 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MCU PF04678.13 OAG26628.1 - 0.053 13.6 2.0 0.067 13.3 0.7 1.7 1 1 0 2 2 2 0 Mitochondrial calcium uniporter Occludin_ELL PF07303.13 OAG26628.1 - 0.057 14.2 0.4 27 5.6 0.0 2.9 2 1 1 3 3 3 0 Occludin homology domain Spc29 PF17082.5 OAG26628.1 - 0.14 12.0 4.2 2.8 7.7 3.0 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Pox_EPC_I2-L1 PF12575.8 OAG26628.1 - 0.18 12.1 0.9 0.32 11.3 0.9 1.3 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF1772 PF08592.11 OAG26628.1 - 0.19 12.1 0.5 0.29 11.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Noelin-1 PF12308.8 OAG26628.1 - 0.37 10.8 2.2 1.2 9.2 1.3 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF2203 PF09969.9 OAG26628.1 - 0.61 10.8 6.1 0.42 11.3 1.3 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DASH_Dad1 PF08649.10 OAG26628.1 - 1.1 9.6 3.1 29 4.9 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad1 zf-CpG_bind_C PF12269.8 OAG26628.1 - 1.8 8.3 4.7 7.5 6.3 1.8 2.7 2 1 0 3 3 3 0 CpG binding protein zinc finger C terminal domain DHR10 PF18595.1 OAG26628.1 - 2.1 8.4 11.0 0.46 10.5 3.4 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 OAG26628.1 - 6 7.4 7.6 1.5e+02 2.9 6.7 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region PBP1_TM PF14812.6 OAG26628.1 - 7.6 7.0 6.9 1.3 9.4 2.6 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_H_Exchanger PF00999.21 OAG26630.1 - 2.7e-57 194.3 41.5 3.7e-57 193.9 41.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Rad4 PF03835.15 OAG26631.1 - 1.1e-14 54.4 1.0 2.2e-14 53.4 1.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 OAG26631.1 - 1.3e-13 51.4 1.9 3.8e-13 49.9 1.9 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SUR7 PF06687.12 OAG26632.1 - 1.1e-40 139.6 5.2 1.3e-40 139.3 5.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4191 PF13829.6 OAG26632.1 - 1.1 8.6 3.7 1 8.7 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SseC PF04888.12 OAG26632.1 - 2.6 7.6 4.8 4 6.9 4.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family S_4TM PF18159.1 OAG26632.1 - 6.2 6.0 5.8 3.3 6.9 3.6 1.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MFS_1 PF07690.16 OAG26634.1 - 1e-27 97.0 33.6 1e-27 97.0 33.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TMPIT PF07851.13 OAG26634.1 - 0.14 11.4 0.1 0.37 10.0 0.1 1.6 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.32 OAG26636.1 - 4.5e-17 62.1 9.1 1.1e-05 26.1 0.3 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG26636.1 - 0.00063 20.0 0.0 0.0048 17.2 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4630 PF15443.6 OAG26636.1 - 0.06 13.5 0.1 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) DUF971 PF06155.12 OAG26636.1 - 0.13 13.0 0.0 3.1 8.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) CNDH2_C PF16858.5 OAG26636.1 - 0.64 9.8 11.1 0.066 13.1 5.4 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 OAG26636.1 - 1.1 7.5 19.6 1.5 7.0 15.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 OAG26636.1 - 6 4.9 27.3 9.6 4.3 27.3 1.2 1 0 0 1 1 1 0 Nop14-like family DPM2 PF07297.12 OAG26637.1 - 2.8e-33 114.0 3.3 3.3e-33 113.8 3.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAG26637.1 - 0.00042 20.2 1.6 0.0005 20.0 1.6 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 OAG26637.1 - 0.00049 19.9 4.6 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Phage_holin_3_6 PF07332.11 OAG26637.1 - 0.0087 16.1 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III TMEM169 PF15052.6 OAG26637.1 - 0.011 15.9 1.0 0.012 15.7 1.0 1.1 1 0 0 1 1 1 0 TMEM169 protein family LapA_dom PF06305.11 OAG26637.1 - 0.014 15.2 0.7 0.014 15.2 0.7 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 OAG26637.1 - 0.026 14.6 0.3 0.026 14.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) MA3 PF02847.17 OAG26638.1 - 1.8e-25 89.1 0.0 4.1e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 MA3 domain DUF4113 PF13438.6 OAG26640.1 - 0.052 13.6 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Glyoxal_oxid_N PF07250.11 OAG26642.1 - 1.4e-37 129.2 0.1 1.2e-36 126.2 0.0 2.5 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAG26642.1 - 1.4e-25 89.4 0.8 2.7e-25 88.5 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 OAG26642.1 - 3.6e-22 78.5 88.9 1.1e-08 35.4 18.5 4.1 4 0 0 4 4 4 3 Chitin recognition protein MFS_1 PF07690.16 OAG26645.1 - 5.4e-28 97.9 32.3 2.7e-27 95.6 30.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DFP PF04127.15 OAG26646.1 - 4.5e-14 52.7 0.0 4.4e-06 26.7 0.0 3.2 1 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein POB3_N PF17292.2 OAG26647.1 - 1.2e-31 109.0 0.2 2.7e-30 104.6 0.1 2.4 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 OAG26647.1 - 9.7e-30 102.3 0.0 1.1e-28 98.9 0.0 2.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OAG26647.1 - 1.7e-26 92.5 0.0 8e-26 90.3 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like YL1 PF05764.13 OAG26647.1 - 2.5 8.1 21.0 1.7 8.7 18.9 1.7 1 1 0 1 1 1 0 YL1 nuclear protein Fungal_trans_2 PF11951.8 OAG26648.1 - 1.1e-11 44.2 0.3 3.2e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26648.1 - 2.6e-07 30.6 11.3 5.1e-07 29.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 OAG26648.1 - 2.4 8.6 5.0 7.4 7.0 5.0 2.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GCD14 PF08704.10 OAG26651.1 - 2.9e-10 40.2 0.1 8.2e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 OAG26651.1 - 5.5e-06 26.1 0.9 9.3e-06 25.4 0.4 1.7 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 OAG26651.1 - 0.0026 17.6 0.0 0.086 12.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG26651.1 - 0.02 15.6 0.0 11 6.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAG26651.1 - 0.05 14.6 0.0 0.31 12.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FAA_hydrolase_N PF09298.11 OAG26651.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Metallophos PF00149.28 OAG26652.1 - 1.5e-18 68.0 5.0 1.5e-18 68.0 5.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG26652.1 - 5.5e-06 26.7 0.1 8e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AMP-binding PF00501.28 OAG26653.1 - 6.4e-73 245.7 0.0 8.5e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG26653.1 - 3e-15 56.9 1.1 5.7e-15 56.1 1.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG26654.1 - 3e-07 29.7 0.2 1.6e-06 27.3 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG26654.1 - 2.9e-06 27.3 9.4 4.6e-06 26.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG26656.1 - 2.7e-20 73.2 0.0 5.1e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2370 PF10176.9 OAG26657.1 - 0.97 9.0 2.8 0.92 9.1 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Alternaria_alternata-Altal1/GCA_001642055.1_Altal1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Alternaria_alternata-Altal1/GCA_001642055.1_Altal1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Alternaria_alternata-Altal1/GCA_001642055.1_Altal1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Alternaria_alternata-Altal1/GCA_001642055.1_Altal1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 14:12:25 2019 # [ok]