# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Fun_ATP-synt_8 PF05933.13 KFH40209.1 - 7.3e-22 77.3 11.6 7.8e-22 77.2 11.6 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) RIC3 PF15361.6 KFH40209.1 - 0.099 13.0 1.6 0.11 12.9 1.6 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 YMF19 PF02326.15 KFH40209.1 - 0.19 12.6 4.2 0.21 12.4 4.2 1.0 1 0 0 1 1 1 0 Plant ATP synthase F0 ATP-synt_A PF00119.20 KFH40210.1 - 1.6e-37 129.5 26.7 1.7e-37 129.4 26.7 1.0 1 0 0 1 1 1 1 ATP synthase A chain Vps16_N PF04841.13 KFH40211.1 - 0.039 12.7 0.1 0.049 12.4 0.1 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region Chlam_OMP6 PF03504.13 KFH40211.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Seryl_tRNA_N PF02403.22 KFH40211.1 - 0.33 11.2 4.2 0.99 9.7 1.4 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Evr1_Alr PF04777.13 KFH40213.1 - 2e-30 105.2 0.2 2e-30 105.2 0.2 1.8 2 0 0 2 2 2 1 Erv1 / Alr family IBR PF01485.21 KFH40215.1 - 3e-11 43.4 14.5 1.4e-10 41.3 4.9 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Spt5_N PF11942.8 KFH40215.1 - 2.9 8.9 9.6 14 6.8 2.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TRP PF06011.12 KFH40216.1 - 7.4e-41 140.3 18.6 2.1e-39 135.4 18.6 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFH40216.1 - 2.1e-23 83.2 0.0 3.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain E7R PF17467.2 KFH40216.1 - 0.38 10.9 0.8 0.83 9.9 0.0 1.9 3 0 0 3 3 3 0 Viral Protein E7 Anoctamin PF04547.12 KFH40217.1 - 2.1e-111 373.0 12.3 2.5e-111 372.7 12.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Glyoxalase PF00903.25 KFH40218.1 - 4.4e-10 39.8 0.0 7.6e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFH40218.1 - 1.8e-09 37.8 0.0 2.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFH40218.1 - 3.6e-07 30.9 0.1 9.1e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFH40218.1 - 0.00024 21.3 0.2 0.001 19.2 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Orbi_VP4 PF05059.12 KFH40218.1 - 0.12 10.4 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP4 core protein DUF1752 PF08550.10 KFH40223.1 - 5.2e-06 26.2 1.0 1.5e-05 24.7 1.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cytochrom_B561 PF03188.16 KFH40224.1 - 1.4e-15 57.6 2.4 2.9e-15 56.6 2.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 KFH40224.1 - 0.023 14.8 5.7 0.23 11.6 1.5 2.9 2 1 1 3 3 3 0 Ferric reductase like transmembrane component DUF4079 PF13301.6 KFH40224.1 - 0.12 12.5 14.7 0.51 10.5 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF4149 PF13664.6 KFH40224.1 - 3.1 8.2 11.1 0.054 13.8 2.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF2162 PF09930.9 KFH40224.1 - 8.1 5.8 15.6 0.2 11.1 0.6 3.0 2 1 1 3 3 3 0 Predicted transporter (DUF2162) ATG16 PF08614.11 KFH40227.1 - 5.1e-54 183.6 20.8 5.8e-54 183.4 20.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FPP PF05911.11 KFH40227.1 - 1.2e-05 23.8 9.5 1.5e-05 23.5 9.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil PI3K_P85_iSH2 PF16454.5 KFH40227.1 - 0.00068 19.3 6.1 0.026 14.1 0.0 2.1 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Filament PF00038.21 KFH40227.1 - 0.0022 17.7 13.5 0.0049 16.5 10.1 1.9 1 1 1 2 2 2 1 Intermediate filament protein APG6_N PF17675.1 KFH40227.1 - 0.0026 18.3 24.3 0.0038 17.8 19.5 2.7 1 1 2 3 3 3 2 Apg6 coiled-coil region PaaA_PaaC PF05138.12 KFH40227.1 - 0.0098 15.1 2.6 0.075 12.2 0.4 2.1 2 0 0 2 2 2 1 Phenylacetic acid catabolic protein DUF4250 PF14056.6 KFH40227.1 - 0.017 15.0 1.7 8.3 6.5 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) Atg14 PF10186.9 KFH40227.1 - 0.03 13.4 10.8 0.035 13.2 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FtsX_ECD PF18075.1 KFH40227.1 - 0.046 14.3 0.9 0.11 13.1 0.5 2.1 1 1 0 1 1 1 0 FtsX extracellular domain UPF0242 PF06785.11 KFH40227.1 - 0.085 12.9 13.1 0.044 13.9 3.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CEP63 PF17045.5 KFH40227.1 - 0.12 12.3 15.1 0.13 12.1 3.5 2.1 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Flagellin_N PF00669.20 KFH40227.1 - 0.15 12.1 2.9 0.16 12.0 1.7 1.7 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF4201 PF13870.6 KFH40227.1 - 0.22 11.2 15.7 0.2 11.4 12.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 KFH40227.1 - 1 10.1 11.3 2.2 9.0 2.9 3.0 2 1 1 3 3 3 0 Initiation control protein YabA GAS PF13851.6 KFH40227.1 - 1.1 8.5 16.9 1.6 8.0 14.6 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KFH40227.1 - 1.4 9.3 14.7 1.2 9.6 12.2 1.8 1 1 1 2 2 2 0 Fez1 BST2 PF16716.5 KFH40227.1 - 3 8.5 11.3 5.6 7.6 6.4 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PAXX PF15384.6 KFH40227.1 - 5.9 6.5 9.0 0.69 9.6 0.6 2.2 1 1 1 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Spc7 PF08317.11 KFH40227.1 - 6.4 5.6 18.4 30 3.3 18.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 KFH40227.1 - 7.1 7.1 17.6 9.7 6.7 0.1 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 KFH40227.1 - 9.8 6.3 17.7 11 6.1 7.5 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Vps16_C PF04840.12 KFH40228.1 - 4.3e-81 272.4 0.0 6.2e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KFH40228.1 - 2e-80 270.6 0.0 2.6e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 KFH40228.1 - 0.00077 19.7 0.0 0.034 14.5 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DOT1 PF08123.13 KFH40229.1 - 3.1e-70 235.9 0.0 6.6e-70 234.8 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KFH40229.1 - 0.048 14.4 0.1 0.25 12.1 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFH40229.1 - 0.08 12.5 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain SR-25 PF10500.9 KFH40229.1 - 0.091 12.4 11.6 0.14 11.7 11.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TraV PF09676.10 KFH40229.1 - 4.7 8.2 8.1 11 7.0 8.1 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Mito_carr PF00153.27 KFH40230.1 - 7.5e-51 170.0 0.1 2.1e-17 62.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.17 KFH40231.1 - 1.1e-44 151.3 2.1 1.4e-44 151.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AMPK1_CBM PF16561.5 KFH40231.1 - 0.08 13.2 0.2 0.26 11.5 0.1 1.9 2 1 1 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase DUF2841 PF11001.8 KFH40233.1 - 2.4e-42 143.9 4.3 3.9e-42 143.2 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) MFS_1 PF07690.16 KFH40234.1 - 1.3e-15 57.2 10.2 1.3e-15 57.2 10.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH40234.1 - 5.1e-12 45.4 0.1 5.1e-12 45.4 0.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MTHFR PF02219.17 KFH40236.1 - 1e-101 340.1 0.0 1.5e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GATase_5 PF13507.6 KFH40237.1 - 5.9e-93 310.7 0.0 9.1e-93 310.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KFH40237.1 - 5.7e-34 117.5 0.7 2.5e-24 86.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KFH40237.1 - 3.4e-23 81.8 0.0 6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KFH40237.1 - 2.1e-21 76.2 0.0 4.8e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Pkinase PF00069.25 KFH40238.1 - 2e-22 79.9 0.0 3.6e-10 39.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40238.1 - 1.9e-06 27.4 0.0 0.002 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Crp PF00325.20 KFH40238.1 - 0.02 14.5 0.2 0.87 9.3 0.2 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family YrhK PF14145.6 KFH40239.1 - 1.8 8.5 23.4 0.27 11.1 4.0 4.7 2 2 2 4 4 4 0 YrhK-like protein DUF2855 PF11017.8 KFH40240.1 - 1.3e-68 232.3 0.0 1.5e-68 232.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) SAM_2 PF07647.17 KFH40241.1 - 8.6e-17 61.0 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFH40241.1 - 4.7e-16 59.0 0.0 9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFH40241.1 - 6.1e-13 49.2 0.0 1.3e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KFH40241.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rootletin PF15035.6 KFH40241.1 - 0.033 14.2 0.2 0.054 13.5 0.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fungal_trans PF04082.18 KFH40242.1 - 0.0031 16.6 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KFH40243.1 - 7.6e-05 21.6 0.1 8.7e-05 21.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RE_ApaLI PF09499.10 KFH40243.1 - 0.052 13.3 0.6 0.064 13.0 0.6 1.1 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease AtuA PF07287.11 KFH40244.1 - 9.3e-127 422.6 0.0 1.1e-126 422.3 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Oxidored_molyb PF00174.19 KFH40246.1 - 7.7e-58 194.9 0.0 1.1e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFH40246.1 - 9.6e-28 96.9 0.3 1.1e-26 93.5 0.4 2.5 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KFH40246.1 - 8.9e-13 48.2 0.2 1.4e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KFH40246.1 - 0.12 12.4 0.3 0.37 11.0 0.3 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat DUF3506 PF12014.8 KFH40247.1 - 9.3e-57 190.9 0.0 2.3e-56 189.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KFH40247.1 - 2.1e-07 30.7 0.5 2.1e-07 30.7 0.5 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFH40247.1 - 4.8e-06 26.3 0.3 2e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 F-box domain zf-met PF12874.7 KFH40249.1 - 0.026 14.9 4.4 0.93 10.0 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFH40249.1 - 0.12 13.3 19.2 0.079 13.8 1.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH40249.1 - 3.6 8.2 17.7 0.14 12.6 1.1 3.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type Pex16 PF08610.10 KFH40250.1 - 3.5e-142 473.3 0.2 4e-142 473.2 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SPT_ssu-like PF11779.8 KFH40251.1 - 2.4e-19 68.7 3.4 3e-19 68.4 3.4 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like PMP1_2 PF08114.11 KFH40251.1 - 0.071 12.9 0.4 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 ATPase proteolipid family Actin PF00022.19 KFH40253.1 - 1.3e-150 501.5 0.0 5.2e-150 499.6 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_L5_C PF00673.21 KFH40254.1 - 3.9e-29 100.7 0.0 6.2e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFH40254.1 - 8.2e-07 29.3 0.2 1.5e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 RF-1 PF00472.20 KFH40255.1 - 3.2e-23 81.9 5.3 3.2e-23 81.9 5.3 1.6 1 1 1 2 2 2 1 RF-1 domain MIR PF02815.19 KFH40255.1 - 0.083 12.7 0.3 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 MIR domain Fes1 PF08609.10 KFH40256.1 - 2.7e-29 101.9 3.2 2.7e-29 101.9 3.2 2.3 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KFH40256.1 - 3.1e-06 27.0 0.0 0.077 13.1 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFH40256.1 - 1.9e-05 25.0 0.2 7.3e-05 23.1 0.1 2.1 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KFH40256.1 - 0.00027 20.9 0.0 0.06 13.6 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KFH40256.1 - 0.0018 18.8 0.1 0.09 13.3 0.0 2.8 1 1 1 2 2 2 2 HEAT-like repeat Atx10homo_assoc PF09759.9 KFH40256.1 - 0.014 15.4 0.6 0.3 11.1 0.1 1.9 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 KFH40256.1 - 0.029 14.5 0.2 0.42 10.7 0.1 2.4 1 1 1 2 2 2 0 V-ATPase subunit H E1-E2_ATPase PF00122.20 KFH40258.1 - 2e-34 118.7 16.3 5.9e-29 100.9 0.0 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH40258.1 - 2.8e-23 82.6 8.6 2.8e-23 82.6 8.6 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFH40258.1 - 2.3e-17 64.0 0.0 6e-13 49.6 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH40258.1 - 4.1e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFH40258.1 - 4.3e-14 51.9 0.0 2.7e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH40258.1 - 0.00031 20.6 0.2 0.00053 19.8 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Porin_3 PF01459.22 KFH40259.1 - 7e-83 278.2 0.1 8.2e-83 278.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 KFH40260.1 - 2.8e-58 196.9 0.0 4.1e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFH40260.1 - 1.6e-21 76.9 0.2 6.3e-21 75.0 0.2 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IstB_IS21 PF01695.17 KFH40260.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ZnuA PF01297.17 KFH40260.1 - 0.091 12.2 0.2 0.48 9.8 0.1 2.2 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic PT-VENN PF04829.13 KFH40260.1 - 4 7.6 4.4 6.2 7.0 2.0 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif UCH_1 PF13423.6 KFH40261.1 - 6.2e-32 111.5 0.0 7.3e-31 107.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFH40261.1 - 6.8e-14 52.0 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PPP4R2 PF09184.11 KFH40263.1 - 0.15 11.6 18.7 0.2 11.2 18.7 1.3 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 KFH40263.1 - 0.26 10.6 16.1 0.32 10.4 16.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 KFH40263.1 - 0.98 9.2 12.0 1.3 8.8 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Astro_capsid_p PF12226.8 KFH40263.1 - 2.2 7.3 20.8 2.9 6.9 20.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 KFH40263.1 - 2.5 7.3 25.3 3.1 7.0 25.3 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 KFH40263.1 - 4.3 6.0 11.2 5.3 5.7 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KFH40263.1 - 5.8 4.9 6.5 8.6 4.3 6.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MSP1_C PF07462.11 KFH40263.1 - 6.8 5.3 9.8 8.3 5.0 9.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Merozoite_SPAM PF07133.11 KFH40263.1 - 7.1 6.6 32.6 11 6.0 32.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CRC_subunit PF08624.10 KFH40264.1 - 8.6e-52 175.2 0.0 1.2e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Rad4 PF03835.15 KFH40266.1 - 6.2e-32 110.3 0.2 1.4e-31 109.2 0.2 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFH40266.1 - 8.1e-30 103.1 0.1 1.9e-29 101.9 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KFH40266.1 - 3.9e-23 81.0 0.0 9.8e-23 79.7 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFH40266.1 - 7.1e-19 68.5 0.1 7.1e-19 68.5 0.1 3.3 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KFH40266.1 - 0.0042 17.5 2.0 0.023 15.1 1.0 2.6 2 1 0 2 2 2 1 Transglutaminase-like superfamily Glyco_transf_64 PF09258.10 KFH40270.1 - 7.8e-56 189.1 0.0 1.2e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KFH40270.1 - 0.064 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Aft1_OSA PF11785.8 KFH40270.1 - 0.12 12.8 0.2 0.34 11.4 0.2 1.8 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain TPT PF03151.16 KFH40271.1 - 1.2e-24 87.2 23.4 1.4e-24 87.0 23.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH40271.1 - 2.2e-05 24.7 37.2 4.8e-05 23.5 12.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFH40271.1 - 0.027 13.7 21.8 0.045 13.0 21.8 1.3 1 0 0 1 1 1 0 UAA transporter family Cupin_2 PF07883.11 KFH40273.1 - 1.8e-08 34.0 0.0 3.9e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KFH40273.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 KFH40273.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF1769 PF08588.10 KFH40274.1 - 1.6e-26 92.2 0.4 3.8e-26 91.0 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Abhydrolase_6 PF12697.7 KFH40275.1 - 4.5e-05 24.2 6.7 4.5e-05 24.2 6.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH40275.1 - 5.7e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KFH40275.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Gly_transf_sug PF04488.15 KFH40276.1 - 7.4e-11 42.5 0.0 1.8e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_M20 PF01546.28 KFH40277.1 - 7.9e-35 120.4 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFH40277.1 - 0.00011 22.0 0.0 0.00037 20.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFH40277.1 - 0.0002 21.1 0.0 0.00052 19.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Acyl_transf_3 PF01757.22 KFH40278.1 - 9e-32 110.5 35.8 1.1e-31 110.2 35.8 1.1 1 0 0 1 1 1 1 Acyltransferase family ABC_tran PF00005.27 KFH40279.1 - 4e-20 72.7 0.0 7.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFH40279.1 - 1e-14 54.9 4.5 2e-14 53.9 4.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 KFH40279.1 - 0.00039 20.4 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 KFH40279.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KFH40279.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KFH40279.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH40279.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Redoxin PF08534.10 KFH40279.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin Ice_nucleation PF00818.17 KFH40279.1 - 0.24 11.5 4.8 0.83 9.9 4.8 2.0 1 0 0 1 1 1 0 Ice nucleation protein repeat RINGv PF12906.7 KFH40280.1 - 0.0001 22.3 7.9 0.00019 21.5 7.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFH40280.1 - 0.013 15.8 10.8 0.026 14.8 10.8 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KFH40280.1 - 0.14 12.3 5.5 0.27 11.4 5.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFH40280.1 - 2 8.3 9.1 3.5 7.5 9.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain bZIP_1 PF00170.21 KFH40281.1 - 2.6e-10 40.2 4.4 2.6e-10 40.2 4.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFH40281.1 - 0.00013 22.0 5.7 0.0003 20.8 5.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFH40281.1 - 0.012 16.1 6.5 0.012 16.1 6.5 2.1 2 1 1 3 3 3 0 bZIP Maf transcription factor CDC45 PF02724.14 KFH40281.1 - 3.9 5.7 7.0 5.3 5.2 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PGK PF00162.19 KFH40282.1 - 4.6e-152 506.4 1.0 5.9e-152 506.0 1.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase SGTA_dimer PF16546.5 KFH40282.1 - 9.1e-25 86.2 0.9 1.8e-24 85.3 0.9 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KFH40282.1 - 1.4e-13 50.0 12.2 1.7e-07 30.8 0.6 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH40282.1 - 3e-13 48.8 15.8 2.7e-06 27.1 0.5 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH40282.1 - 1.6e-09 37.3 7.5 6.5e-06 25.7 0.8 3.9 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 KFH40282.1 - 2.2e-07 31.4 19.5 1.1e-06 29.2 9.3 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH40282.1 - 7.8e-06 25.7 10.0 0.085 13.1 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH40282.1 - 5.1e-05 23.7 14.5 0.1 13.5 0.1 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFH40282.1 - 9.5e-05 22.5 8.0 0.0051 17.1 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH40282.1 - 0.00011 22.7 6.7 0.0069 16.9 1.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFH40282.1 - 0.00016 21.5 2.0 0.092 12.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PA PF02225.22 KFH40282.1 - 0.0003 20.7 1.8 0.027 14.5 0.0 3.5 3 0 0 3 3 3 1 PA domain STI1 PF17830.1 KFH40282.1 - 0.003 17.5 7.5 0.003 17.5 7.5 2.4 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 KFH40282.1 - 0.0068 16.5 3.5 0.013 15.6 1.7 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFH40282.1 - 0.021 15.1 10.5 0.025 14.9 4.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFH40282.1 - 0.081 13.4 6.0 0.67 10.4 1.6 2.4 1 1 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 KFH40282.1 - 0.22 11.6 4.0 5.4 7.2 1.4 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.11 KFH40282.1 - 0.39 10.5 4.2 0.42 10.4 2.6 1.9 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.6 KFH40282.1 - 1.6 9.6 6.2 4.6 8.1 0.4 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Mis14 PF08641.12 KFH40284.1 - 2.7 8.3 7.9 13 6.1 7.9 2.0 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Brr6_like_C_C PF10104.9 KFH40287.1 - 9.1e-30 103.2 0.1 1.2e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.18 KFH40289.1 - 1.8e-19 69.8 0.9 2.4e-19 69.4 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH40289.1 - 1.6e-07 31.3 11.9 2.9e-07 30.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Period_C PF12114.8 KFH40289.1 - 0.47 10.0 5.9 0.91 9.1 5.9 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Med3 PF11593.8 KFH40289.1 - 1.3 8.2 8.3 7.6 5.6 9.6 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Macoilin PF09726.9 KFH40289.1 - 2.6 6.5 6.5 3.4 6.1 6.5 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KFH40289.1 - 3.9 6.6 8.9 3.9 6.6 7.1 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein Med26 PF08711.11 KFH40290.1 - 2.5e-10 40.2 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 KFH40291.1 - 4.8e-43 147.4 0.2 7e-23 81.3 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40291.1 - 9.9e-15 54.5 0.3 5.6e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase HRXXH PF13933.6 KFH40294.1 - 5.1e-103 343.9 0.0 6.1e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KFH40294.1 - 2.3e-06 28.2 0.0 4.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KFH40294.1 - 0.0002 20.4 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Peptidase_M28 PF04389.17 KFH40295.1 - 5.1e-30 104.6 0.0 7.5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 KFH40296.1 - 1.1e-15 58.1 0.4 1.1e-15 58.1 0.4 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DPBB_1 PF03330.18 KFH40297.1 - 0.0016 18.7 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KFH40297.1 - 0.084 12.7 0.2 0.1 12.4 0.2 1.3 1 1 0 1 1 1 0 Barwin family Methyltransf_2 PF00891.18 KFH40298.1 - 2e-25 89.3 0.1 3.3e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFH40298.1 - 0.00019 21.3 0.2 0.0029 17.6 0.0 2.6 2 1 1 3 3 3 1 Dimerisation domain Methyltransf_25 PF13649.6 KFH40298.1 - 0.0013 19.4 0.1 0.0032 18.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain SPOUT_MTase PF02590.17 KFH40298.1 - 0.023 14.7 0.1 0.37 10.8 0.0 2.5 3 0 0 3 3 3 0 Predicted SPOUT methyltransferase MarR PF01047.22 KFH40298.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 MarR family Methyltransf_32 PF13679.6 KFH40298.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFH40298.1 - 0.099 12.2 0.2 0.24 10.9 0.1 1.8 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFH40298.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8 PF00082.22 KFH40299.1 - 9.2e-45 153.2 0.5 1.5e-44 152.5 0.5 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KFH40299.1 - 2.4e-15 57.2 0.0 5.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KFH40299.1 - 9.2e-07 28.8 0.0 3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 KFH40299.1 - 0.0019 18.0 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain RPT PF13446.6 KFH40299.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein FAD_binding_4 PF01565.23 KFH40300.1 - 4.6e-18 65.3 3.1 2e-17 63.2 0.5 2.8 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KFH40300.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DPBB_1 PF03330.18 KFH40301.1 - 4.5e-07 30.0 0.0 6.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KFH40301.1 - 0.092 12.6 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Barwin family MFS_1 PF07690.16 KFH40302.1 - 8.3e-36 123.6 24.4 1.8e-35 122.5 24.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 KFH40303.1 - 6.8e-15 56.0 0.0 8.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH40303.1 - 0.042 14.1 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KFH40303.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OB_NTP_bind PF07717.16 KFH40304.1 - 4.2e-23 81.5 0.0 4.4e-22 78.2 0.0 2.6 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFH40304.1 - 6.1e-19 68.3 0.0 1.5e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH40304.1 - 2.7e-11 43.8 0.0 1.5e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH40304.1 - 1.1e-07 31.9 0.1 2.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFH40304.1 - 8.4e-05 22.9 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFH40304.1 - 0.00056 19.6 0.2 0.0021 17.7 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KFH40304.1 - 0.00077 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFH40304.1 - 0.005 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFH40304.1 - 0.011 15.7 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFH40304.1 - 0.012 16.0 0.1 0.025 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFH40304.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aminotran_5 PF00266.19 KFH40305.1 - 9.9e-28 97.1 0.0 1.3e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SCAB_CC PF16712.5 KFH40305.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein B12-binding PF02310.19 KFH40305.1 - 0.088 12.8 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain PRMT5_TIM PF17285.2 KFH40306.1 - 1.1e-69 234.5 0.0 1.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KFH40306.1 - 1.1e-66 223.9 0.0 2.2e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFH40306.1 - 1.7e-58 197.4 0.0 2.5e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KFH40306.1 - 0.24 11.2 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CBM_1 PF00734.18 KFH40307.1 - 3.7e-13 49.2 17.2 1.1e-12 47.7 17.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_2 PF02230.16 KFH40307.1 - 9e-07 28.9 0.3 1.4e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFH40307.1 - 3.3e-05 23.5 1.1 0.0002 20.9 0.3 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFH40307.1 - 0.00038 20.0 0.3 0.00063 19.3 0.3 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 KFH40307.1 - 0.029 14.0 0.5 0.061 13.0 0.5 1.6 1 1 0 1 1 1 0 Putative esterase NOA36 PF06524.12 KFH40307.1 - 0.046 13.0 3.0 0.061 12.6 3.0 1.1 1 0 0 1 1 1 0 NOA36 protein DLH PF01738.18 KFH40307.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Toxin_7 PF05980.12 KFH40307.1 - 0.31 11.3 10.1 0.7 10.2 10.1 1.7 1 0 0 1 1 1 0 Toxin 7 CENP-B_dimeris PF09026.10 KFH40307.1 - 8.8 6.8 12.8 17 5.9 12.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.8 KFH40308.1 - 0.92 9.6 7.6 0.19 11.9 4.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) HET PF06985.11 KFH40309.1 - 1.7e-15 57.7 0.3 3.2e-15 56.7 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) dCMP_cyt_deam_1 PF00383.23 KFH40311.1 - 5.9e-07 29.3 0.0 1.8e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFH40311.1 - 0.016 14.9 0.0 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 MafB19-like deaminase 6PF2K PF01591.18 KFH40312.1 - 4.5e-70 235.4 0.0 1.5e-50 171.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFH40312.1 - 8.2e-26 90.9 0.2 6.1e-24 84.8 0.0 2.8 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFH40312.1 - 0.0016 18.6 0.1 0.024 14.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFH40312.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PhoU PF01895.19 KFH40312.1 - 0.089 13.3 0.3 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 PhoU domain CARD PF00619.21 KFH40312.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain RNA_pol_A_bac PF01000.26 KFH40313.1 - 1.3e-32 112.5 0.0 2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFH40313.1 - 5.3e-19 67.4 0.0 7.1e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calycin_like PF13944.6 KFH40313.1 - 0.078 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Calycin-like beta-barrel domain tRNA-synt_2d PF01409.20 KFH40314.1 - 8.6e-47 159.7 0.0 2.2e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFH40314.1 - 1.4e-24 86.4 0.0 3.1e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Sof1 PF04158.14 KFH40316.1 - 6.3e-31 106.5 17.3 6.3e-31 106.5 17.3 1.9 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 KFH40316.1 - 7.2e-31 105.8 9.5 7.9e-06 26.5 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40316.1 - 1.3e-09 38.2 1.0 0.011 16.0 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH40316.1 - 8.2e-05 21.7 0.1 0.64 8.9 0.0 3.4 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFH40316.1 - 0.00014 20.6 0.8 0.096 11.2 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain BBS2_Mid PF14783.6 KFH40316.1 - 0.077 13.0 0.0 30 4.7 0.0 4.0 2 2 3 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.27 KFH40317.1 - 2.9e-49 164.9 0.5 3.6e-18 65.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein HisKA_4TM PF16926.5 KFH40317.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase GN3L_Grn1 PF08701.11 KFH40318.1 - 6.6e-25 87.0 17.2 1.2e-24 86.2 17.2 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KFH40318.1 - 1.6e-16 60.4 0.0 3.2e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH40318.1 - 1.8e-08 34.5 0.0 7.9e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KFH40318.1 - 5.4e-06 26.1 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFH40318.1 - 1.4e-05 25.2 6.2 0.14 12.2 0.1 4.1 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 KFH40318.1 - 0.0029 17.2 0.2 0.058 12.9 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFH40318.1 - 0.015 14.3 0.1 0.015 14.3 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 KFH40318.1 - 0.06 13.7 0.6 0.97 9.8 0.0 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_16 PF13191.6 KFH40318.1 - 0.082 13.3 0.1 0.082 13.3 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KFH40318.1 - 0.12 12.9 1.1 0.42 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Nop14 PF04147.12 KFH40318.1 - 1.5 6.9 19.1 2.7 6.1 19.1 1.3 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 KFH40319.1 - 1.1e-57 195.5 0.0 1.3e-56 191.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40319.1 - 6e-27 94.5 0.2 7.5e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH40319.1 - 9.6e-05 21.5 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFH40319.1 - 0.00028 20.9 2.4 0.036 14.0 0.3 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KFH40319.1 - 0.00047 19.6 0.1 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFH40319.1 - 0.0015 17.9 0.4 0.0027 17.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFH40319.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KFH40319.1 - 0.5 9.9 2.4 0.82 9.2 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Aminotran_3 PF00202.21 KFH40320.1 - 1.6e-42 145.6 0.1 1.6e-40 139.0 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-III RNB PF00773.19 KFH40321.1 - 1.1e-98 330.6 0.3 1.7e-98 330.0 0.3 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KFH40321.1 - 3.4e-31 107.1 1.0 6.3e-31 106.2 0.1 2.0 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KFH40321.1 - 1.5e-29 102.6 0.1 5.1e-29 100.9 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KFH40321.1 - 2.2e-19 69.3 0.0 7.4e-19 67.6 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KFH40321.1 - 2e-10 41.0 0.2 8.2e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KFH40321.1 - 3.4e-07 30.3 0.7 0.03 14.5 0.0 3.4 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 KFH40321.1 - 0.013 15.8 0.0 0.056 13.8 0.0 2.1 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 KFH40321.1 - 0.15 11.8 0.0 0.52 10.0 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain SF3A2 PF16835.5 KFH40322.1 - 2.2e-34 117.7 0.1 3.3e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CactinC_cactus PF09732.9 KFH40322.1 - 2.2e-06 27.6 0.2 3.2e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein zf-met PF12874.7 KFH40322.1 - 4.2e-06 27.0 0.9 7e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KFH40322.1 - 0.06 12.9 1.5 0.11 12.0 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Tim54 PF11711.8 KFH40323.1 - 6.8e-144 479.3 0.7 7.9e-144 479.1 0.7 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Acyl_transf_3 PF01757.22 KFH40324.1 - 5.3e-43 147.4 32.5 8.7e-43 146.7 32.5 1.3 1 0 0 1 1 1 1 Acyltransferase family Y_phosphatase3 PF13350.6 KFH40325.1 - 5.3e-48 164.0 0.0 6.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFH40325.1 - 0.00032 20.3 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFH40325.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GST_N_3 PF13417.6 KFH40326.1 - 5e-09 36.5 0.1 8.9e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH40326.1 - 8.8e-08 32.1 0.3 1.7e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH40326.1 - 0.00052 20.2 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFH40326.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SMP PF04927.12 KFH40327.1 - 3.5e-12 46.6 14.4 8.5e-09 35.8 4.9 2.1 1 1 1 2 2 2 2 Seed maturation protein Ifi-6-16 PF06140.13 KFH40327.1 - 0.0085 16.0 0.9 0.16 11.9 0.1 2.1 2 0 0 2 2 2 1 Interferon-induced 6-16 family Amidohydro_3 PF07969.11 KFH40328.1 - 2.9e-67 228.2 2.8 3.6e-67 227.9 2.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KFH40328.1 - 0.00093 18.6 0.8 0.07 12.4 0.8 2.8 1 1 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.16 KFH40332.1 - 9.1e-17 61.0 10.8 1.8e-16 60.0 10.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1270 PF06900.11 KFH40332.1 - 2.5 8.6 8.8 1.3 9.4 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DAGAT PF03982.13 KFH40333.1 - 2.7e-93 312.2 0.0 3.7e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SUN PF03856.13 KFH40335.1 - 2.8e-87 292.2 7.1 3.4e-87 291.9 7.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Dus PF01207.17 KFH40335.1 - 0.086 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Glyco_hydro_114 PF03537.13 KFH40336.1 - 3.6e-62 209.7 0.0 4.3e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 zf-H2C2_2 PF13465.6 KFH40337.1 - 3.8e-14 52.4 17.7 1.8e-07 31.3 2.0 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFH40337.1 - 6.2e-10 39.0 24.3 0.0039 17.6 8.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH40337.1 - 8.9e-08 32.3 21.5 0.03 15.1 6.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KFH40337.1 - 0.0012 18.6 3.5 0.15 11.9 0.5 3.0 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KFH40337.1 - 0.0017 18.3 18.5 0.14 12.2 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger bZIP_1 PF00170.21 KFH40337.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor zf-Di19 PF05605.12 KFH40337.1 - 0.11 12.8 12.2 0.2 12.0 7.0 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFH40337.1 - 0.13 12.2 3.5 3 7.7 0.3 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 KFH40337.1 - 0.27 11.2 10.0 0.43 10.5 4.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFH40337.1 - 0.31 11.2 6.4 0.89 9.7 1.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 KFH40337.1 - 0.34 11.4 15.1 0.54 10.8 0.7 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.9 KFH40337.1 - 0.37 10.9 7.5 0.6 10.2 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KFH40337.1 - 0.44 10.5 6.1 0.24 11.3 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TF_Zn_Ribbon PF08271.12 KFH40337.1 - 1.4 8.5 3.2 4.5 6.9 0.7 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 KFH40337.1 - 1.5 8.9 6.8 14 5.8 6.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 KFH40337.1 - 2.3 8.3 7.5 1.2 9.2 3.8 2.3 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_9 PF14369.6 KFH40337.1 - 2.5 8.4 4.1 40 4.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_jaz PF12171.8 KFH40337.1 - 3.1 8.2 8.5 3.1 8.2 3.5 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ZapB PF06005.12 KFH40337.1 - 3.5 8.1 5.5 0.62 10.5 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB FYDLN_acid PF09538.10 KFH40337.1 - 8.6 7.1 8.9 10 6.8 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) SKA1 PF07160.12 KFH40338.1 - 0.0011 18.9 1.0 0.0013 18.7 1.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 E2R135 PF11570.8 KFH40338.1 - 0.019 15.2 2.8 0.06 13.6 2.2 1.8 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 FTA4 PF13093.6 KFH40338.1 - 0.067 13.1 2.0 0.075 12.9 2.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 KFH40338.1 - 0.07 13.7 6.1 0.077 13.5 6.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFH40338.1 - 0.078 12.3 1.3 0.089 12.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 KFH40338.1 - 0.091 12.4 3.0 0.11 12.2 3.0 1.1 1 0 0 1 1 1 0 GrpE SWI-SNF_Ssr4 PF08549.10 KFH40338.1 - 0.28 9.8 2.6 0.32 9.6 2.6 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Snapin_Pallidin PF14712.6 KFH40338.1 - 0.34 11.4 6.1 0.39 11.2 5.0 1.6 1 1 1 2 2 2 0 Snapin/Pallidin Acetyltransf_1 PF00583.25 KFH40339.1 - 3.6e-09 36.9 0.1 4.2e-09 36.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH40339.1 - 7.5e-08 32.7 0.0 1.7e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH40339.1 - 2.3e-07 30.8 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH40339.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KFH40339.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Thioredoxin PF00085.20 KFH40342.1 - 1.1e-23 83.2 0.0 1.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFH40342.1 - 3.8e-06 26.5 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFH40342.1 - 2.3e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KFH40342.1 - 3.4e-05 23.8 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KFH40342.1 - 4e-05 24.0 0.1 0.00014 22.3 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KFH40342.1 - 0.00025 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFH40342.1 - 0.00029 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 KFH40342.1 - 0.003 17.5 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFH40342.1 - 0.0042 16.8 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFH40342.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein SseB_C PF14581.6 KFH40344.1 - 0.037 14.1 0.1 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 SseB protein C-terminal domain THDPS_M PF14789.6 KFH40344.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle SUV3_C PF12513.8 KFH40345.1 - 3.6e-11 42.8 0.1 8.4e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KFH40345.1 - 7e-10 38.6 0.1 1.9e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KFH40345.1 - 2.4e-08 34.3 0.0 5.4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4267 PF14087.6 KFH40347.1 - 3.1e-05 24.0 0.6 4.6e-05 23.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DSPc PF00782.20 KFH40348.1 - 2.3e-06 27.4 0.0 4.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFH40348.1 - 0.0061 16.8 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 Rit1 DUSP-like domain Synaptobrevin PF00957.21 KFH40349.1 - 5.1e-32 109.5 0.3 6.7e-32 109.1 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFH40349.1 - 1.4e-28 98.7 0.0 2.5e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.25 KFH40350.1 - 4.9e-16 58.8 0.0 2.4e-15 56.5 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFH40350.1 - 6.8e-08 32.6 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFH40350.1 - 1.3e-06 28.1 0.0 4.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH40350.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AA_permease PF00324.21 KFH40352.1 - 1.8e-125 419.3 36.7 2.2e-125 419.0 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH40352.1 - 5.1e-38 131.0 39.1 6.4e-38 130.7 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF389 PF04087.14 KFH40352.1 - 0.062 13.3 0.5 0.062 13.3 0.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF389) AA_permease_2 PF13520.6 KFH40355.1 - 3.2e-65 220.6 46.4 4e-65 220.3 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH40355.1 - 6.4e-32 110.8 44.1 8.7e-32 110.3 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 KFH40356.1 - 1e-06 28.8 6.7 1.9e-06 27.9 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFH40357.1 - 5.1e-27 94.7 36.5 5.1e-27 94.7 36.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fis1_TPR_C PF14853.6 KFH40358.1 - 7.6e-25 86.7 2.7 1.1e-24 86.2 2.7 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFH40358.1 - 1.5e-17 62.9 0.8 2.1e-17 62.5 0.1 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFH40358.1 - 0.038 14.1 2.3 0.081 13.1 2.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Septin PF00735.18 KFH40359.1 - 3e-118 394.2 0.1 3e-118 394.2 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFH40359.1 - 1.9e-08 34.4 0.9 4.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH40359.1 - 9.5e-06 25.3 1.2 0.00028 20.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFH40359.1 - 7e-05 23.4 0.8 0.021 15.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KFH40359.1 - 0.001 18.4 1.5 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KFH40359.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFH40359.1 - 0.002 18.6 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFH40359.1 - 0.0021 18.0 0.9 0.0021 18.0 0.9 3.3 3 1 0 3 3 2 1 RsgA GTPase Ras PF00071.22 KFH40359.1 - 0.0055 16.3 0.5 0.041 13.5 0.0 2.5 3 0 0 3 3 3 1 Ras family AAA_29 PF13555.6 KFH40359.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH40359.1 - 0.018 15.3 1.0 0.037 14.3 0.0 2.1 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFH40359.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFH40359.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFH40359.1 - 0.085 12.9 7.7 0.85 9.7 0.0 3.4 3 1 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 KFH40359.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFH40359.1 - 0.098 13.0 0.5 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KFH40359.1 - 0.18 11.5 2.5 9.1 6.0 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KFH40359.1 - 0.19 11.8 1.3 3.1 7.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Exonuc_VII_L PF02601.15 KFH40359.1 - 0.35 10.4 6.7 0.54 9.8 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Caldesmon PF02029.15 KFH40359.1 - 0.76 8.5 16.3 1.1 7.9 16.3 1.3 1 0 0 1 1 1 0 Caldesmon DUF87 PF01935.17 KFH40359.1 - 3.5 7.7 6.8 4.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain UPF0242 PF06785.11 KFH40359.1 - 3.6 7.6 14.3 6.4 6.8 14.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MnmE_helical PF12631.7 KFH40359.1 - 3.7 7.7 5.7 7.2 6.7 5.7 1.4 1 0 0 1 1 1 0 MnmE helical domain Atg14 PF10186.9 KFH40359.1 - 6.7 5.7 8.5 10 5.1 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ku PF02735.16 KFH40360.1 - 3.2e-46 157.6 0.0 1.5e-45 155.4 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFH40360.1 - 3.7e-36 124.9 0.0 5.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KFH40360.1 - 4.5e-26 91.4 1.1 4.5e-26 91.4 1.1 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KFH40360.1 - 7.8e-11 41.5 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KFH40360.1 - 0.018 14.7 0.0 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain Complex1_51K PF01512.17 KFH40360.1 - 0.077 12.9 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.19 KFH40361.1 - 3.2e-99 332.0 0.0 3.7e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KFH40361.1 - 0.067 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) p450 PF00067.22 KFH40362.1 - 1.1e-67 228.8 0.0 1.4e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KFH40363.1 - 9e-26 90.5 0.0 1.9e-25 89.5 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH40363.1 - 1.7e-18 67.0 0.1 2.5e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH40363.1 - 2.7e-10 40.5 0.0 4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFH40363.1 - 4e-05 23.2 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFH40363.1 - 7e-05 22.4 0.0 8.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFH40363.1 - 0.0031 16.7 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SLD5_C PF16922.5 KFH40363.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Shikimate_DH PF01488.20 KFH40363.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NolV PF06635.12 KFH40364.1 - 0.04 13.3 0.1 0.087 12.2 0.0 1.5 2 0 0 2 2 2 0 Nodulation protein NolV FAD_binding_3 PF01494.19 KFH40365.1 - 3.7e-66 223.7 0.2 4.6e-66 223.4 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFH40365.1 - 1.3e-06 28.6 0.1 5.8e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KFH40365.1 - 1.7e-06 27.9 0.0 4.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH40365.1 - 3.1e-05 23.3 0.0 7.9e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFH40365.1 - 0.0002 21.6 0.1 0.00046 20.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 KFH40365.1 - 0.00023 20.4 0.1 0.00058 19.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFH40365.1 - 0.00075 18.3 0.3 0.017 13.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFH40365.1 - 0.00091 18.6 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH40365.1 - 0.0021 17.4 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KFH40365.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFH40365.1 - 0.0042 17.3 0.1 0.013 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFH40365.1 - 0.0045 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KFH40365.1 - 0.0084 15.5 0.3 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFH40365.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase ApbA PF02558.16 KFH40365.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFH40365.1 - 0.041 12.9 0.3 0.082 11.9 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KFH40365.1 - 0.046 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 KFH40365.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus PKD PF00801.20 KFH40365.1 - 0.2 11.5 0.9 14 5.6 0.0 3.2 2 1 0 2 2 2 0 PKD domain ADH_N_2 PF16884.5 KFH40366.1 - 6.1e-30 103.3 0.0 1.3e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFH40366.1 - 5.8e-19 68.4 0.0 9.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH40366.1 - 5.8e-08 33.9 0.0 1.1e-07 32.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Chorismate_bind PF00425.18 KFH40367.1 - 1.9e-69 234.1 0.0 4.2e-65 219.9 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KFH40367.1 - 2.6e-25 89.3 0.0 7.2e-25 87.9 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KFH40367.1 - 1.3e-14 54.6 0.0 3.2e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KFH40367.1 - 0.0006 19.6 1.1 0.0083 15.9 1.1 2.2 1 1 0 1 1 1 1 Peptidase C26 ADH_zinc_N PF00107.26 KFH40368.1 - 3.8e-25 88.4 0.5 7.6e-25 87.4 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH40368.1 - 4.2e-12 45.9 0.1 1.6e-11 44.1 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH40368.1 - 5.9e-11 43.6 0.0 1.2e-10 42.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KFH40368.1 - 0.00082 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KFH40368.1 - 0.0045 16.3 0.2 0.0073 15.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 KFH40368.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 SIS domain Amidase PF01425.21 KFH40369.1 - 1.6e-79 268.0 0.0 6.6e-79 266.0 0.0 1.8 1 1 0 1 1 1 1 Amidase PBP1_TM PF14812.6 KFH40370.1 - 2.1 8.8 7.7 3.7 8.0 7.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_25 PF13649.6 KFH40372.1 - 1.7e-14 54.2 0.0 3.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40372.1 - 5.8e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40372.1 - 1.3e-08 34.9 0.1 3.3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40372.1 - 1.9e-07 31.0 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40372.1 - 2.1e-06 28.4 0.0 4.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH40372.1 - 9.4e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFH40372.1 - 0.0087 15.6 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFH40372.1 - 0.011 15.7 0.0 0.079 13.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KFH40372.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KFH40372.1 - 0.033 14.0 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.20 KFH40372.1 - 0.054 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SOG2 PF10428.9 KFH40372.1 - 0.44 9.7 30.3 0.82 8.8 30.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4321 PF14209.6 KFH40373.1 - 0.55 10.1 2.5 0.98 9.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) Phage_antitermQ PF06530.12 KFH40374.1 - 0.085 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q DUF4042 PF13251.6 KFH40374.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Exo_endo_phos PF03372.23 KFH40375.1 - 1.7e-20 73.6 0.0 5.1e-19 68.7 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFH40375.1 - 5.5e-08 32.4 6.6 2.7e-05 23.9 0.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFH40375.1 - 9.5e-07 29.1 3.7 0.0015 18.9 0.1 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH40375.1 - 7.4 7.6 7.1 32 5.6 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich Repeat Goodbye PF17109.5 KFH40376.1 - 1.6e-12 47.9 0.0 9.8e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KFH40376.1 - 1.5e-07 32.0 0.0 4.6e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFH40376.1 - 5.4e-07 29.7 0.0 1.4e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFH40376.1 - 0.0023 18.2 0.1 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFH40376.1 - 0.01 16.3 1.1 0.072 13.5 0.2 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KFH40376.1 - 0.01 15.0 0.4 0.048 12.8 0.4 2.0 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KFH40376.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KFH40376.1 - 0.019 14.7 0.1 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 KFH40376.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KFH40376.1 - 0.03 14.5 0.3 0.16 12.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KFH40376.1 - 0.032 14.2 0.0 0.074 12.9 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KFH40376.1 - 0.057 12.5 0.0 0.16 11.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Glyco_trans_2_3 PF13632.6 KFH40376.1 - 0.16 11.9 0.8 1.1 9.1 0.1 2.6 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Glyco_hydro_3_C PF01915.22 KFH40377.1 - 2.8e-62 210.3 0.0 4.6e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH40377.1 - 2.6e-43 148.6 0.0 4.2e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFH40377.1 - 2.4e-25 88.4 0.2 5.3e-25 87.3 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KFH40377.1 - 1.3e-20 73.7 0.2 2.8e-20 72.6 0.2 1.6 1 1 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 KFH40377.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family bZIP_1 PF00170.21 KFH40378.1 - 0.17 12.0 16.4 9 6.5 16.4 2.3 1 1 0 1 1 1 0 bZIP transcription factor Macoilin PF09726.9 KFH40378.1 - 1.5 7.2 8.3 2.2 6.7 8.3 1.2 1 0 0 1 1 1 0 Macoilin family eRF1_2 PF03464.15 KFH40381.1 - 2.7e-48 163.7 0.1 4.6e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFH40381.1 - 2.7e-40 137.4 0.4 5.9e-40 136.3 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFH40381.1 - 3.3e-21 75.6 0.0 5.4e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KFH40381.1 - 5.1e-11 43.0 0.1 2.7e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KFH40381.1 - 1.7e-10 41.3 0.0 2.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 KFH40381.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PfkB PF00294.24 KFH40382.1 - 1.3e-23 83.8 0.0 1.5e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WHIM1 PF15612.6 KFH40383.1 - 0.00023 20.6 0.0 0.00052 19.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 ParE_toxin PF05016.15 KFH40383.1 - 0.053 14.1 0.5 0.12 13.0 0.5 1.5 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Menin PF05053.13 KFH40383.1 - 6.3 5.0 4.8 9.2 4.5 4.8 1.2 1 0 0 1 1 1 0 Menin EST1_DNA_bind PF10373.9 KFH40384.1 - 4.6e-52 177.2 0.0 9e-52 176.3 0.0 1.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFH40384.1 - 2.9e-21 76.5 0.0 8.4e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 DUF1770 PF08589.10 KFH40385.1 - 2.2e-37 128.0 1.3 2.6e-37 127.7 1.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) VASt PF16016.5 KFH40386.1 - 7.2e-34 117.4 2.4 1.3e-32 113.3 0.5 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KFH40386.1 - 3e-16 59.9 0.0 5.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFH40386.1 - 7.4e-07 29.6 0.0 1.9e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PH domain BAR PF03114.18 KFH40386.1 - 0.0022 17.7 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 KFH40386.1 - 0.0039 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF4019 PF13211.6 KFH40386.1 - 0.58 10.6 4.1 0.71 10.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) PfkB PF00294.24 KFH40387.1 - 2.1e-37 129.0 0.0 2.6e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L2_C PF03947.18 KFH40388.1 - 9.4e-43 145.4 4.0 1.4e-42 144.9 4.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFH40388.1 - 0.0096 15.9 0.1 0.11 12.5 0.1 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain F-box PF00646.33 KFH40390.1 - 0.046 13.6 0.2 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 F-box domain Bac_rhamnosid6H PF17389.2 KFH40391.1 - 1.7e-113 379.3 2.8 2.2e-113 379.0 2.8 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KFH40391.1 - 3.4e-57 193.0 0.1 6.8e-57 192.0 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KFH40391.1 - 2.8e-30 104.3 0.0 5.9e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KFH40391.1 - 1.2e-22 79.5 0.2 1.5e-20 72.8 0.4 2.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sulfate_transp PF00916.20 KFH40392.1 - 3e-78 263.2 12.4 4.5e-78 262.7 12.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFH40392.1 - 6.6e-16 58.0 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFH40392.1 - 0.00061 20.1 0.0 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 STAS domain Thiolase_N PF00108.23 KFH40393.1 - 4.9e-64 216.2 0.0 6.4e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH40393.1 - 1.5e-41 140.9 0.2 3.3e-41 139.8 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFH40393.1 - 0.086 12.7 0.1 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MU117 PF15474.6 KFH40394.1 - 1.3e-16 61.3 5.2 2.6e-16 60.2 5.2 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene family PSDC PF12588.8 KFH40395.1 - 8.2e-43 145.7 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KFH40395.1 - 5.2e-28 98.0 0.0 1e-26 93.8 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase LOH1CR12 PF10158.9 KFH40396.1 - 0.049 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein T5orf172 PF10544.9 KFH40397.1 - 1.3e-08 35.2 9.9 1.2e-07 32.2 3.7 3.4 2 1 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KFH40397.1 - 1.6e-08 35.1 6.5 1.6e-08 35.1 1.4 2.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Pectate_lyase PF03211.13 KFH40399.1 - 3.7e-86 287.8 7.2 4.3e-86 287.6 7.2 1.0 1 0 0 1 1 1 1 Pectate lyase UQ_con PF00179.26 KFH40401.1 - 1.9e-41 141.0 0.0 2.4e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH40401.1 - 7.8e-06 25.6 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFH40401.1 - 0.043 13.7 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KFH40401.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 RWD domain MIOX PF05153.15 KFH40402.1 - 4.2e-120 399.9 0.2 6.9e-120 399.2 0.0 1.4 2 0 0 2 2 2 1 Myo-inositol oxygenase NOG1_N PF17835.1 KFH40402.1 - 0.04 13.9 1.0 1.6 8.7 0.0 2.8 2 1 1 3 3 3 0 NOG1 N-terminal helical domain Nop52 PF05997.12 KFH40403.1 - 2.5e-44 151.6 0.0 3.7e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 RabGAP-TBC PF00566.18 KFH40404.1 - 7.9e-37 127.0 0.3 5.2e-20 72.0 0.0 3.3 2 1 0 2 2 2 2 Rab-GTPase-TBC domain CorA PF01544.18 KFH40407.1 - 8.8e-10 38.4 0.1 2.2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Utp14 PF04615.13 KFH40407.1 - 0.023 13.3 2.6 0.041 12.5 2.6 1.3 1 0 0 1 1 1 0 Utp14 protein GCIP PF13324.6 KFH40407.1 - 0.37 10.4 2.0 0.9 9.1 2.0 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KFH40407.1 - 1.9 7.7 12.6 5 6.4 12.6 1.6 1 0 0 1 1 1 0 NOA36 protein Apt1 PF10351.9 KFH40407.1 - 2.6 6.8 5.3 0.3 9.9 0.7 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Vezatin PF12632.7 KFH40408.1 - 1.6e-68 231.1 0.0 2.4e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes BPD_transp_2 PF02653.16 KFH40408.1 - 0.03 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF1835 PF08874.10 KFH40409.1 - 0.17 12.1 0.5 0.44 10.7 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) GATA PF00320.27 KFH40410.1 - 4.2e-14 51.9 0.9 8.5e-14 50.9 0.9 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF2353 PF09789.9 KFH40410.1 - 0.0002 20.8 0.6 0.00024 20.6 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 KFH40410.1 - 0.0032 17.5 16.8 0.087 12.9 1.8 2.4 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFH40410.1 - 0.012 14.6 11.1 0.016 14.1 11.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TACC_C PF05010.14 KFH40410.1 - 0.047 13.5 5.3 0.067 13.0 5.3 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 KFH40410.1 - 0.087 12.4 12.3 0.14 11.7 11.8 1.5 1 1 0 1 1 1 0 Intermediate filament protein AalphaY_MDB PF04611.12 KFH40410.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region ArfGap PF01412.18 KFH40410.1 - 0.14 12.3 0.9 0.21 11.6 0.1 1.8 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf Pox_A_type_inc PF04508.12 KFH40410.1 - 0.17 11.8 0.4 0.17 11.8 0.4 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 KFH40410.1 - 0.37 9.8 10.0 0.75 8.8 10.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 KFH40410.1 - 0.4 10.4 10.5 0.055 13.2 6.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KFH40410.1 - 0.54 10.3 2.3 0.9 9.6 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Herpes_UL25 PF01499.16 KFH40410.1 - 0.71 8.3 7.5 1.1 7.8 7.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family ATG16 PF08614.11 KFH40410.1 - 1.2 9.3 18.0 0.044 14.0 10.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 KFH40410.1 - 1.4 8.1 2.3 2 7.6 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein SHE3 PF17078.5 KFH40410.1 - 1.5 8.5 10.6 3.9 7.1 9.6 1.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CdvA PF18822.1 KFH40410.1 - 1.8 8.4 10.0 1.6 8.6 5.4 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF1043 PF06295.12 KFH40410.1 - 2.1 8.4 5.4 3.7 7.6 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TMCO5 PF14992.6 KFH40410.1 - 2.5 7.6 9.0 3.4 7.2 9.0 1.1 1 0 0 1 1 1 0 TMCO5 family Fmp27_WPPW PF10359.9 KFH40410.1 - 5.5 5.7 8.4 8.1 5.2 8.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain JIP_LZII PF16471.5 KFH40410.1 - 6.9 6.9 14.3 6.4 7.0 1.9 3.3 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 KFH40410.1 - 8.8 6.4 13.6 11 6.0 13.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Acetyltransf_1 PF00583.25 KFH40411.1 - 0.00079 19.7 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 KFH40411.1 - 0.052 13.0 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 zinc_ribbon_10 PF10058.9 KFH40412.1 - 0.029 14.1 0.2 0.029 14.1 0.2 2.4 1 1 2 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein C1_2 PF03107.16 KFH40412.1 - 0.25 11.7 7.8 0.3 11.4 7.8 1.2 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 KFH40412.1 - 0.32 11.2 11.0 2.8 8.2 4.8 2.2 1 1 1 2 2 2 0 B-box zinc finger Mit_KHE1 PF10173.9 KFH40413.1 - 1.5e-56 191.5 0.5 1.5e-56 191.5 0.5 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Svf1_C PF17187.4 KFH40414.1 - 8e-63 211.2 0.0 1.2e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KFH40414.1 - 6.7e-55 185.6 0.0 9e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain NatB_MDM20 PF09797.9 KFH40416.1 - 0.072 12.0 0.0 0.08 11.9 0.0 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit UPF0444 PF15475.6 KFH40416.1 - 0.13 12.6 0.5 3.1 8.1 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 MOSC PF03473.17 KFH40417.1 - 3.7e-26 91.7 0.0 5.6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFH40417.1 - 2.1e-12 46.9 0.0 5e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain EthD PF07110.11 KFH40420.1 - 5.9e-06 27.3 0.0 0.0048 18.0 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KFH40420.1 - 0.0056 17.1 0.0 0.8 10.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Abhydrolase_2 PF02230.16 KFH40422.1 - 2.2e-31 109.3 0.0 1.5e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 KFH40422.1 - 8.2e-08 32.2 0.0 1.5e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFH40422.1 - 2.9e-07 30.2 1.2 8.3e-05 22.2 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFH40422.1 - 6e-07 30.3 2.7 8.5e-07 29.8 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH40422.1 - 0.0002 20.7 1.3 0.026 13.8 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KFH40422.1 - 0.00048 19.8 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFH40422.1 - 0.0037 17.2 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KFH40422.1 - 0.051 13.1 0.1 0.075 12.5 0.1 1.4 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KFH40422.1 - 0.11 12.1 0.1 1.7 8.2 0.1 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold Mannosyl_trans2 PF04188.13 KFH40423.1 - 3.6e-50 171.6 12.4 5.4e-50 171.0 12.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF4834 PF16118.5 KFH40426.1 - 2.1 9.3 5.3 2.8 9.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NPC1_N PF16414.5 KFH40427.1 - 7.9e-83 277.7 5.3 1.2e-82 277.2 5.3 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KFH40427.1 - 3.8e-73 246.9 13.7 7.8e-48 163.2 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFH40427.1 - 1.2e-51 174.5 4.3 1.2e-51 174.5 4.3 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFH40427.1 - 4.9e-05 22.4 9.5 4.9e-05 22.4 9.5 3.2 2 2 0 2 2 2 1 MMPL family Folate_rec PF03024.14 KFH40427.1 - 0.0019 18.1 0.6 0.0043 16.9 0.6 1.5 1 0 0 1 1 1 1 Folate receptor family Glyco_hydro_47 PF01532.20 KFH40428.1 - 1.7e-139 465.7 0.9 1.9e-139 465.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.13 KFH40428.1 - 2.2e-05 25.0 1.4 0.036 14.6 0.0 3.1 3 0 0 3 3 3 2 TipAS antibiotic-recognition domain Rad10 PF03834.14 KFH40429.1 - 9.6e-48 160.9 0.0 1.3e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KFH40429.1 - 0.066 13.8 0.0 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Lactamase_B_2 PF12706.7 KFH40430.1 - 3.3e-31 108.4 0.0 6e-30 104.3 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFH40430.1 - 9.7e-11 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFH40430.1 - 5.8e-05 23.2 2.5 0.0012 18.9 1.6 2.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Spuma_A9PTase PF03539.14 KFH40430.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) MR_MLE_C PF13378.6 KFH40431.1 - 1e-58 198.5 0.0 1.3e-57 194.9 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFH40431.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KFH40431.1 - 0.0057 15.9 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF4307 PF14155.6 KFH40433.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) Gly_kinase PF02595.15 KFH40434.1 - 9.9e-127 422.9 2.6 1.1e-126 422.7 2.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family APH PF01636.23 KFH40436.1 - 7.1e-15 55.6 0.1 1.2e-14 54.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH40436.1 - 0.0021 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RNA_polI_A14 PF08203.11 KFH40436.1 - 0.034 14.9 0.0 0.058 14.1 0.0 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Fructosamin_kin PF03881.14 KFH40436.1 - 0.039 13.2 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Arylsulfotran_2 PF14269.6 KFH40437.1 - 6.6e-46 157.0 2.0 9.4e-46 156.5 2.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFH40437.1 - 8.1e-19 67.8 2.6 2e-18 66.5 2.6 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SDA1 PF05285.12 KFH40437.1 - 0.18 11.2 15.4 0.25 10.7 15.4 1.1 1 0 0 1 1 1 0 SDA1 Cyclin_N PF00134.23 KFH40439.1 - 4.9e-09 36.0 0.0 8.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain COesterase PF00135.28 KFH40440.1 - 3.2e-76 257.3 0.0 6.3e-76 256.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH40440.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH40440.1 - 0.058 12.9 0.2 0.13 11.7 0.3 1.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 KFH40441.1 - 2.4e-20 72.8 27.2 1.1e-16 60.7 8.2 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH40441.1 - 3.6e-08 32.7 2.3 3.6e-08 32.7 2.3 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFH40441.1 - 0.046 12.0 1.5 4.3 5.5 0.0 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF463 PF04317.12 KFH40442.1 - 0.25 10.2 0.2 0.34 9.8 0.2 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 adh_short PF00106.25 KFH40443.1 - 1.4e-28 99.7 0.0 3.1e-28 98.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH40443.1 - 3.2e-20 72.7 0.5 4.7e-20 72.2 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH40443.1 - 6.9e-11 42.4 0.1 1.2e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Chal_sti_synt_C PF02797.15 KFH40443.1 - 0.066 13.2 0.0 5.6 6.9 0.0 2.2 1 1 1 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain LDB19 PF13002.7 KFH40444.1 - 2.1e-32 112.4 0.1 4.6e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KFH40444.1 - 1.4e-05 25.1 0.0 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain AA_permease_2 PF13520.6 KFH40445.1 - 6.3e-49 166.9 33.4 7.8e-49 166.6 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH40445.1 - 4.3e-17 61.9 26.4 4.3e-17 61.9 26.4 2.3 2 1 0 2 2 2 2 Amino acid permease DUF1980 PF09323.10 KFH40446.1 - 8.9 6.2 8.7 0.92 9.4 3.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) Polysacc_deac_1 PF01522.21 KFH40447.1 - 3e-26 91.7 0.0 4.1e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KFH40447.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Albumin_I_a PF16720.5 KFH40448.1 - 0.13 12.2 0.0 0.54 10.2 0.0 2.1 1 0 0 1 1 1 0 Albumin I chain a Glyco_hydro_11 PF00457.17 KFH40449.1 - 4.3e-62 208.9 18.0 2.7e-61 206.3 18.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 11 FAR1 PF03101.15 KFH40450.1 - 6.4e-09 36.4 1.4 1.1e-08 35.7 1.4 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain VSP PF03302.13 KFH40452.1 - 0.0047 15.8 0.1 0.0066 15.3 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein TraL PF07178.11 KFH40452.1 - 0.11 13.0 0.2 0.17 12.3 0.2 1.3 1 0 0 1 1 1 0 TraL protein Zip PF02535.22 KFH40452.1 - 0.55 9.4 3.8 3 7.0 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF347 PF03988.12 KFH40452.1 - 2.2 8.5 5.7 0.22 11.7 1.0 1.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) PH PF00169.29 KFH40453.1 - 2.4e-07 31.2 0.0 6.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFH40453.1 - 0.0005 20.4 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_S9_N PF02897.15 KFH40453.1 - 0.022 13.6 0.1 0.033 13.0 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pkinase PF00069.25 KFH40454.1 - 3.5e-60 203.6 0.0 8.2e-60 202.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40454.1 - 1.6e-24 86.6 0.0 2.8e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFH40454.1 - 1.4e-09 38.1 0.0 8e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFH40454.1 - 0.0031 17.8 0.0 0.021 15.1 0.0 2.3 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KFH40454.1 - 0.0056 15.5 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase LpxI_N PF17930.1 KFH40454.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.8 1 0 0 1 1 1 0 LpxI N-terminal domain DUF726 PF05277.12 KFH40455.1 - 9e-125 416.1 2.2 1.3e-124 415.6 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SpoIIE PF07228.12 KFH40456.1 - 1.2e-05 25.3 0.0 5.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFH40456.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFH40456.1 - 0.14 11.7 0.0 0.68 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C Fcf1 PF04900.12 KFH40457.1 - 4.2e-30 104.1 0.0 7.6e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Fcf1 Nop53 PF07767.11 KFH40457.1 - 0.037 13.4 25.8 0.061 12.7 25.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3439 PF11921.8 KFH40457.1 - 0.44 10.5 9.5 0.76 9.7 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FXMRP1_C_core PF12235.8 KFH40457.1 - 1.4 9.6 17.4 3.2 8.4 17.4 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal YABBY PF04690.13 KFH40457.1 - 4.4 7.9 7.2 3 8.4 5.3 1.7 1 1 1 2 2 2 0 YABBY protein Zn_clus PF00172.18 KFH40458.1 - 1.2e-08 34.9 12.8 1.8e-08 34.4 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UTP15_C PF09384.10 KFH40459.1 - 7e-52 175.0 0.1 1.2e-51 174.3 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFH40459.1 - 8.3e-16 58.1 8.9 7e-05 23.5 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40459.1 - 2.5e-07 30.9 0.1 0.063 13.6 0.0 4.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFH40459.1 - 5.4e-05 23.2 0.0 2.8 8.0 0.0 4.4 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFH40459.1 - 0.013 14.1 0.2 3.6 6.1 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CPSF_A PF03178.15 KFH40459.1 - 0.021 14.2 0.0 0.095 12.0 0.0 1.8 1 1 0 2 2 2 0 CPSF A subunit region adh_short PF00106.25 KFH40462.1 - 3.6e-13 49.4 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH40462.1 - 1.6e-10 40.9 0.0 9.6e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DEAD PF00270.29 KFH40463.1 - 1.2e-15 57.7 0.0 3e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFH40463.1 - 4.3e-13 49.6 0.0 1.3e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH40463.1 - 6.1e-08 33.0 0.0 2.7e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 KFH40463.1 - 0.051 13.0 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Glyco_hydro_47 PF01532.20 KFH40464.1 - 6.3e-138 460.5 0.0 7.1e-138 460.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KFH40464.1 - 0.25 9.8 0.0 11 4.3 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Pyr_redox_2 PF07992.14 KFH40466.1 - 9.5e-32 110.4 0.1 1.2e-31 110.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH40466.1 - 2.9e-06 27.7 0.6 8.3e-05 23.1 1.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH40466.1 - 0.00019 20.7 0.0 0.011 14.9 0.1 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFH40466.1 - 0.00033 20.7 0.2 0.065 13.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KFH40466.1 - 0.00035 20.2 0.5 1.3 8.5 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFH40466.1 - 0.003 16.7 0.2 1.6 7.7 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFH40466.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH40466.1 - 0.068 13.4 0.0 6 7.2 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NUDIX PF00293.28 KFH40467.1 - 1.1e-26 93.4 0.0 1.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RPA_C PF08784.11 KFH40468.1 - 1e-20 74.4 0.1 2.6e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFH40468.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ACBP PF00887.19 KFH40469.1 - 2e-15 56.7 1.5 3.1e-15 56.1 1.5 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein ExsD PF16806.5 KFH40469.1 - 0.011 15.7 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Antiactivator protein ExsD SbsC_C PF18058.1 KFH40469.1 - 0.051 13.8 0.9 0.59 10.4 0.1 2.0 1 1 0 2 2 2 0 SbsC C-terminal domain End3 PF12761.7 KFH40470.1 - 1.8e-77 260.0 2.4 2.6e-77 259.5 2.4 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KFH40470.1 - 4.1e-48 161.6 0.0 8.1e-47 157.5 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFH40470.1 - 3.7e-07 29.2 0.2 9.8e-07 27.9 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFH40470.1 - 6.7e-06 26.5 0.3 2.9e-05 24.4 0.0 2.3 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFH40470.1 - 0.0012 18.6 0.2 0.0039 17.0 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KFH40470.1 - 0.0016 18.3 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFH40470.1 - 0.019 14.4 0.1 0.058 12.9 0.1 1.9 1 0 0 1 1 1 0 EF hand Spectrin PF00435.21 KFH40470.1 - 1 9.9 6.7 1.1 9.8 3.5 2.4 2 1 0 2 2 1 0 Spectrin repeat DUF4407 PF14362.6 KFH40470.1 - 1.5 8.1 6.7 6.5 6.0 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.24 KFH40470.1 - 1.8 8.5 5.5 6.1 6.7 1.7 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 KFH40470.1 - 2.7 8.5 6.8 22 5.6 0.9 3.7 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein CSN5_C PF18323.1 KFH40470.1 - 3.4 8.7 5.7 0.96 10.4 1.1 2.6 3 1 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain MscS_porin PF12795.7 KFH40470.1 - 4.2 6.9 10.5 0.31 10.6 2.6 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4140 PF13600.6 KFH40470.1 - 5.5 7.5 7.1 7.1 7.1 0.1 2.8 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) Syntaxin-6_N PF09177.11 KFH40470.1 - 6.4 7.4 7.4 1.2e+02 3.3 7.4 3.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 KFH40470.1 - 6.8 6.1 8.7 0.25 10.8 0.9 2.2 2 1 0 3 3 3 0 Golgin subfamily A member 5 Acetyltransf_7 PF13508.7 KFH40471.1 - 2.5e-07 31.0 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH40471.1 - 1.3e-06 28.4 0.0 3.5e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH40471.1 - 5.2e-06 26.6 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH40471.1 - 5.6e-06 26.6 0.1 8.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFH40471.1 - 0.0078 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFH40471.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Lon_C PF05362.13 KFH40472.1 - 3.7e-68 229.1 0.2 6.1e-68 228.4 0.2 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFH40472.1 - 9.4e-27 94.2 0.0 2e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFH40472.1 - 1.7e-22 80.3 0.0 3.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH40472.1 - 3.5e-08 33.5 0.0 1.4e-07 31.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KFH40472.1 - 1.5e-07 31.3 0.6 1.3e-06 28.3 0.0 2.5 3 0 0 3 3 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KFH40472.1 - 5.3e-06 26.9 0.0 2.7e-05 24.6 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KFH40472.1 - 3.4e-05 24.0 0.0 0.0001 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFH40472.1 - 5.1e-05 23.1 0.1 0.00023 20.9 0.0 2.1 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KFH40472.1 - 5.6e-05 23.0 0.0 0.00023 21.0 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH40472.1 - 0.00018 21.8 0.1 0.011 16.0 0.0 2.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KFH40472.1 - 0.0002 21.1 0.2 0.00075 19.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFH40472.1 - 0.0037 17.4 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFH40472.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KFH40472.1 - 0.018 15.4 0.0 0.074 13.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 KFH40472.1 - 0.025 14.5 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KFH40472.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH40472.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFH40472.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFH40472.1 - 0.047 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KFH40472.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KFH40472.1 - 0.063 12.6 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFH40472.1 - 0.09 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFH40472.1 - 0.098 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFH40472.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFH40472.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase AAA_17 PF13207.6 KFH40472.1 - 0.16 12.4 0.8 0.77 10.2 0.1 2.6 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 KFH40472.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 KFH40472.1 - 0.19 12.2 0.0 0.19 12.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain C2 PF00168.30 KFH40474.1 - 4e-08 33.5 0.0 7.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain Pkinase_C PF00433.24 KFH40474.1 - 0.0017 19.0 2.9 0.0027 18.4 0.2 2.9 2 0 0 2 2 2 1 Protein kinase C terminal domain ATP_sub_h PF10775.9 KFH40475.1 - 3e-25 88.0 0.8 5.1e-25 87.3 0.6 1.5 1 1 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KFH40475.1 - 0.0056 17.1 0.0 0.0077 16.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 LSM PF01423.22 KFH40476.1 - 0.00028 20.5 0.0 0.00039 20.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Fe_hyd_lg_C PF02906.14 KFH40477.1 - 1e-52 179.3 0.0 2.6e-52 177.9 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Lactococcin_972 PF09683.10 KFH40477.1 - 0.27 11.8 1.3 8.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) WD40 PF00400.32 KFH40478.1 - 6.9e-40 134.3 23.8 9.4e-10 38.9 2.2 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40478.1 - 1.4e-16 60.6 1.5 0.042 14.1 0.2 6.0 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KFH40478.1 - 1.6e-12 46.8 2.3 3e-12 45.9 2.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KFH40478.1 - 0.009 15.0 0.0 18 4.2 0.0 4.7 2 2 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KFH40478.1 - 0.0094 15.3 0.1 0.43 9.8 0.0 2.3 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KFH40478.1 - 0.01 15.2 0.0 3.3 7.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain Cyclin_N PF00134.23 KFH40479.1 - 2.6e-11 43.4 0.2 5.4e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFH40479.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF3792 PF12670.7 KFH40480.1 - 0.02 15.0 3.3 0.031 14.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) SUZ PF12752.7 KFH40481.1 - 0.00011 22.9 8.3 0.00011 22.9 8.3 4.2 3 1 1 4 4 4 1 SUZ domain SUZ-C PF12901.7 KFH40481.1 - 0.0022 18.0 1.3 0.0022 18.0 1.3 2.1 2 0 0 2 2 2 1 SUZ-C motif Synaphin PF05835.12 KFH40481.1 - 4.5 7.5 11.3 2.1 8.6 4.6 2.1 2 0 0 2 2 2 0 Synaphin protein DUF4629 PF15442.6 KFH40481.1 - 5.9 7.1 9.9 1.4 9.1 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4629) Sulfate_transp PF00916.20 KFH40482.1 - 1.1e-101 340.4 16.8 1.3e-101 340.1 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFH40482.1 - 1.6e-06 27.8 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFH40482.1 - 0.015 15.6 0.1 0.043 14.2 0.1 1.7 1 0 0 1 1 1 0 STAS domain Glyco_transf_22 PF03901.17 KFH40483.1 - 2.4e-85 287.3 15.8 2.9e-85 287.0 15.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M28 PF04389.17 KFH40484.1 - 3.4e-26 92.2 0.0 6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFH40484.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 PTAC PF06130.12 KFH40484.1 - 0.15 12.3 0.4 0.98 9.6 0.3 2.4 3 0 0 3 3 3 0 Phosphate propanoyltransferase Acetyltransf_7 PF13508.7 KFH40485.1 - 0.00031 21.1 0.0 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH40485.1 - 0.00073 19.6 0.1 0.0022 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH40485.1 - 0.00073 19.8 0.2 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF3143 PF11341.8 KFH40485.1 - 0.007 16.7 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3143) Acetyltransf_10 PF13673.7 KFH40485.1 - 0.049 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFH40485.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Peptidase_M17_N PF02789.17 KFH40485.1 - 0.2 11.5 0.8 0.41 10.5 0.8 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Fungal_trans_2 PF11951.8 KFH40486.1 - 0.023 13.5 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KFH40487.1 - 1e-35 123.4 53.9 1.4e-35 122.8 50.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PalH PF08733.10 KFH40487.1 - 0.35 9.8 7.2 0.71 8.8 7.2 1.4 1 0 0 1 1 1 0 PalH/RIM21 TMEM43 PF07787.12 KFH40487.1 - 4.1 6.7 10.0 0.066 12.6 2.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 Sld5 PF05916.11 KFH40488.1 - 2.3e-31 108.5 0.0 3.3e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF4663 PF15668.5 KFH40489.1 - 0.69 8.9 3.3 1.3 8.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) AAA_12 PF13087.6 KFH40490.1 - 3.2e-22 79.2 0.0 5.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH40490.1 - 7.9e-09 35.7 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFH40490.1 - 3.5e-07 30.2 0.6 0.0037 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH40490.1 - 5.1e-06 26.9 0.0 1.7e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFH40490.1 - 0.0026 17.6 0.0 0.45 10.4 0.0 3.0 3 0 0 3 3 3 1 Helicase SpecificRecomb PF10136.9 KFH40490.1 - 0.052 11.9 0.1 0.079 11.3 0.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Gar1 PF04410.14 KFH40491.1 - 2.1e-48 164.0 0.4 4.1e-48 163.0 0.4 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region NQR2_RnfD_RnfE PF03116.15 KFH40491.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family M20_dimer PF07687.14 KFH40492.1 - 3.6e-21 75.1 0.0 5.6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFH40492.1 - 6.4e-19 68.5 0.4 5.1e-18 65.5 0.4 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KFH40492.1 - 9.1e-06 25.5 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 KFH40493.1 - 1.4e-21 77.1 0.0 1.6e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40493.1 - 2.5e-15 56.5 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH40493.1 - 0.0004 19.8 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH40493.1 - 0.089 12.7 0.5 1.1 9.2 0.6 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH40493.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Peptidase_C97 PF05903.14 KFH40494.1 - 0.00031 20.6 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 KFH40494.1 - 0.0031 17.2 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF778 PF05608.12 KFH40494.1 - 0.007 16.7 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF778) LRAT PF04970.13 KFH40494.1 - 0.051 13.9 0.8 0.89 9.9 0.8 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF3301 PF11743.8 KFH40494.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) BNR_2 PF13088.6 KFH40495.1 - 0.0016 17.8 0.1 0.0074 15.6 0.1 1.9 1 1 0 1 1 1 1 BNR repeat-like domain BNR_4 PF15892.5 KFH40495.1 - 0.0076 15.6 0.1 0.038 13.3 0.1 2.1 1 1 0 1 1 1 1 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 KFH40495.1 - 0.044 12.6 0.3 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFH40495.1 - 0.74 10.1 3.7 38 4.9 0.0 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Peptidase_C69 PF03577.15 KFH40496.1 - 4.2e-21 75.3 0.0 5.9e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 Cofilin_ADF PF00241.20 KFH40497.1 - 6.1e-25 87.4 0.0 7.1e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HhH-GPD PF00730.25 KFH40498.1 - 2.2e-20 73.1 0.0 4.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KFH40498.1 - 9.5e-18 64.2 0.0 2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KFH40498.1 - 1.7e-05 24.5 0.1 4.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif PPDK_N PF01326.19 KFH40499.1 - 1.4e-108 363.0 0.0 2e-108 362.6 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 KFH40499.1 - 9.8e-63 212.0 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 KFH40499.1 - 6.4e-25 86.7 1.4 1.6e-24 85.4 1.4 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain p450 PF00067.22 KFH40500.1 - 1.5e-43 149.3 0.0 3.9e-43 147.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Allantoicase PF03561.15 KFH40501.1 - 1.4e-96 320.2 0.3 3.3e-47 160.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat RabGAP-TBC PF00566.18 KFH40502.1 - 1e-34 120.1 0.0 1.8e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_binding PF10199.9 KFH40502.1 - 0.2 12.3 3.7 12 6.5 0.4 3.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MFS_1 PF07690.16 KFH40503.1 - 2.7e-36 125.2 35.9 3.6e-36 124.8 34.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Carn_acyltransf PF00755.20 KFH40504.1 - 2.3e-104 350.1 0.0 3.1e-104 349.7 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KFH40504.1 - 9.5e-78 261.3 0.0 2.1e-77 260.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFH40504.1 - 3.5e-54 184.5 0.2 8.5e-54 183.2 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KFH40504.1 - 8.1e-54 182.9 0.2 1.6e-53 181.9 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFH40504.1 - 8.6e-47 159.4 0.0 2.5e-46 157.9 0.0 1.9 2 0 0 2 2 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFH40504.1 - 2.2e-27 95.4 1.4 6.7e-27 93.9 1.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH40504.1 - 3.8e-18 66.8 0.0 2.4e-16 61.0 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH40504.1 - 4.7e-17 62.6 0.0 1.4e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KFH40504.1 - 8.7e-16 58.1 0.0 4.8e-15 55.7 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KFH40504.1 - 1e-12 48.5 0.7 5e-08 33.4 0.1 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFH40504.1 - 2.4e-12 47.4 0.0 8.6e-12 45.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40504.1 - 3.4e-10 40.4 0.0 1.2e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40504.1 - 5.5e-09 36.1 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40504.1 - 2.8e-07 30.4 0.0 7.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH40504.1 - 3.4e-06 26.7 0.0 8.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 KFH40504.1 - 2.2e-05 24.0 0.4 7e-05 22.3 0.4 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KFH40504.1 - 0.00075 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KFH40504.1 - 0.001 19.4 0.1 0.003 17.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KFH40504.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KFH40504.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KFH40504.1 - 0.042 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DIL PF01843.19 KFH40505.1 - 2.3e-32 111.3 1.0 2.3e-32 111.3 1.0 1.6 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KFH40505.1 - 1.1e-19 70.8 0.0 2.3e-11 44.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH40505.1 - 1.3e-12 47.9 0.3 1.5e-06 28.6 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH40505.1 - 1.6e-09 37.8 0.0 1.3e-06 28.5 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFH40505.1 - 6.9e-09 35.8 0.3 0.024 15.1 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KFH40505.1 - 3.7e-08 33.0 0.0 0.24 12.1 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ribosomal_L17 PF01196.19 KFH40506.1 - 3e-31 108.2 0.6 6e-31 107.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 KFH40506.1 - 0.025 14.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain SUZ PF12752.7 KFH40507.1 - 1.2e-14 54.8 1.6 1.2e-14 54.8 1.6 4.3 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 KFH40507.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain ALAD PF00490.21 KFH40508.1 - 1.1e-120 402.7 0.0 1.3e-120 402.4 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PPR_2 PF13041.6 KFH40509.1 - 1.7e-16 60.2 0.0 0.0017 18.5 0.0 5.6 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KFH40509.1 - 9.6e-10 38.4 0.0 7.5e-05 22.7 0.0 4.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KFH40509.1 - 7.5e-07 29.0 0.0 3 8.3 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 KFH40509.1 - 1.1e-05 25.0 0.0 1.2 8.9 0.0 4.1 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 KFH40509.1 - 0.0021 17.5 0.1 0.28 10.5 0.0 2.7 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP NYN PF01936.18 KFH40509.1 - 0.066 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 NYN domain Mac PF12464.8 KFH40510.1 - 6.4e-11 42.3 0.1 1.3e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KFH40510.1 - 8.9e-11 41.1 19.5 2.7e-07 30.1 1.1 3.7 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFH40510.1 - 8.4e-10 38.2 17.2 0.00029 20.5 10.6 2.8 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KFH40510.1 - 1.1e-09 38.3 8.6 2.1e-09 37.3 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MitMem_reg PF13012.6 KFH40512.1 - 1.8e-17 63.7 1.0 2.9e-17 63.1 0.3 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFH40512.1 - 3.7e-17 62.4 0.0 6.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KFH40512.1 - 0.17 11.9 0.0 1.4 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) zf-CCHC_3 PF13917.6 KFH40513.1 - 1.1e-09 38.1 0.9 1.9e-09 37.3 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle AIM5 PF17050.5 KFH40514.1 - 4.4e-23 81.9 4.2 4.4e-23 81.9 4.2 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF883 PF05957.13 KFH40514.1 - 3.6 8.2 15.5 2.8 8.6 4.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) cwf18 PF08315.12 KFH40515.1 - 5.9e-46 156.5 8.5 5.9e-46 156.5 8.5 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF2528 PF10800.8 KFH40515.1 - 0.037 14.6 0.1 0.073 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Pro_CA PF00484.19 KFH40518.1 - 6.4e-51 172.7 0.0 8e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 KFH40518.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily DUF3636 PF12331.8 KFH40519.1 - 2.2e-42 144.4 0.1 4e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KFH40519.1 - 0.0032 16.1 0.2 1 7.8 0.2 2.2 2 0 0 2 2 2 2 DNA damage checkpoint protein Golgin_A5 PF09787.9 KFH40519.1 - 0.05 13.1 9.5 0.085 12.3 9.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KFH40519.1 - 0.31 10.4 10.0 0.51 9.6 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amidase PF01425.21 KFH40520.1 - 1.7e-67 228.3 0.3 6.9e-66 223.0 0.3 2.7 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KFH40521.1 - 2.9e-40 138.3 44.5 2.9e-40 138.3 44.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH40521.1 - 2.4e-08 33.3 11.0 2.4e-08 33.3 11.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter CTP_transf_1 PF01148.20 KFH40523.1 - 3.1e-82 276.3 21.7 3.8e-82 276.0 21.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TFR_dimer PF04253.15 KFH40524.1 - 1.7e-24 86.2 0.0 3.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFH40524.1 - 8.3e-24 84.4 0.0 1.4e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH40524.1 - 8.7e-13 48.1 0.8 5.4e-12 45.6 0.1 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KFH40524.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KFH40524.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Nicastrin E1-E2_ATPase PF00122.20 KFH40525.1 - 1e-33 116.4 19.5 9.6e-29 100.2 0.3 3.3 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH40525.1 - 7.7e-30 103.9 1.1 7.7e-30 103.9 1.1 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFH40525.1 - 1.8e-19 69.6 0.0 5.2e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH40525.1 - 4.8e-19 69.5 0.0 9.6e-15 55.4 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH40525.1 - 4.5e-15 55.1 0.0 1.1e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH40525.1 - 7e-08 32.5 0.5 1.1e-05 25.3 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase AAA_12 PF13087.6 KFH40526.1 - 2.9e-20 72.8 0.0 5.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH40526.1 - 2.1e-07 31.0 0.0 0.0064 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFH40526.1 - 2.3e-05 24.2 0.0 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH40526.1 - 3.8e-05 24.0 0.0 0.00041 20.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH40526.1 - 0.0078 16.6 0.1 0.028 14.8 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KFH40526.1 - 0.025 14.3 0.0 7.6 6.2 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFH40526.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 KFH40526.1 - 0.15 11.9 0.0 0.58 10.0 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-C2H2 PF00096.26 KFH40527.1 - 1.1e-20 72.8 48.5 0.00012 22.4 1.7 7.9 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH40527.1 - 6.8e-13 48.3 47.9 0.015 16.1 0.8 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH40527.1 - 5.9e-11 42.3 52.3 0.0006 20.1 0.3 8.9 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFH40527.1 - 8.4e-05 22.5 39.0 0.0004 20.3 0.7 6.8 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH40527.1 - 0.0022 18.2 26.6 0.14 12.5 0.5 7.1 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFH40527.1 - 0.01 16.1 17.3 0.087 13.1 1.2 4.2 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 KFH40527.1 - 0.051 14.0 0.7 0.051 14.0 0.7 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFH40527.1 - 0.66 10.1 15.4 0.69 10.0 0.1 4.3 2 1 2 5 5 5 0 Aberrant zinc-finger zf-CCHC_2 PF13696.6 KFH40527.1 - 6.8 6.6 7.6 4.6 7.2 0.6 3.1 2 0 0 2 2 2 0 Zinc knuckle Ogr_Delta PF04606.12 KFH40527.1 - 8.7 6.4 15.5 13 5.8 2.4 4.4 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger Tropomyosin PF00261.20 KFH40528.1 - 0.018 14.4 3.4 0.029 13.7 3.4 1.3 1 0 0 1 1 1 0 Tropomyosin DUF1690 PF07956.11 KFH40528.1 - 0.019 15.4 3.3 0.019 15.4 3.3 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Baculo_PEP_C PF04513.12 KFH40528.1 - 0.02 14.9 0.9 0.035 14.2 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KFH40528.1 - 0.021 13.5 1.5 0.032 12.9 1.5 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 KFH40528.1 - 0.037 14.4 4.9 0.067 13.5 4.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 KFH40528.1 - 0.073 13.6 1.3 0.14 12.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 APG6_N PF17675.1 KFH40528.1 - 0.19 12.3 3.1 0.33 11.5 3.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KFH40528.1 - 0.21 10.4 2.4 0.36 9.7 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ApoO PF09769.9 KFH40528.1 - 0.31 11.0 4.0 2.4 8.1 0.9 2.7 2 1 1 3 3 3 0 Apolipoprotein O Fzo_mitofusin PF04799.13 KFH40528.1 - 0.59 9.7 2.7 0.89 9.1 2.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 KFH40528.1 - 0.62 10.1 2.6 0.42 10.6 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 KFH40528.1 - 1.2 9.8 9.3 0.62 10.7 5.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KFH40528.1 - 9.3 5.5 12.0 18 4.6 12.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HA2 PF04408.23 KFH40529.1 - 4.2e-22 78.5 0.0 4.2e-22 78.5 0.0 3.3 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFH40529.1 - 1.5e-19 70.1 0.0 6.8e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFH40529.1 - 3e-14 53.3 0.0 7.3e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFH40529.1 - 2.3e-06 27.9 0.1 9.9e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KFH40529.1 - 3.1e-06 27.1 0.0 8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KFH40529.1 - 0.00045 20.6 0.1 0.0011 19.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH40529.1 - 0.00049 19.9 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 KFH40529.1 - 0.0023 18.0 0.0 0.73 9.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFH40529.1 - 0.0025 17.5 0.1 0.0055 16.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFH40529.1 - 0.0026 17.7 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 KFH40529.1 - 0.0075 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KFH40529.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KFH40529.1 - 0.011 14.6 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KFH40529.1 - 0.027 15.0 0.2 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 KFH40529.1 - 0.042 13.9 0.2 0.27 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain GAD PF02938.14 KFH40529.1 - 0.044 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 GAD domain ATPase PF06745.13 KFH40529.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFH40529.1 - 0.065 13.7 0.0 0.065 13.7 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_29 PF13555.6 KFH40529.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH40529.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SpoIIIAH PF12685.7 KFH40529.1 - 2 8.2 8.3 0.28 11.0 2.4 2.2 1 1 1 2 2 2 0 SpoIIIAH-like protein ChaC PF04752.12 KFH40532.1 - 2.2e-36 125.6 0.0 3.6e-36 124.9 0.0 1.3 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.32 KFH40534.1 - 6.9e-15 55.2 7.9 0.0088 16.9 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40534.1 - 2.8e-06 27.6 0.6 0.0035 17.6 0.2 3.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH40534.1 - 1.8e-05 23.6 1.7 0.00019 20.2 1.8 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 HpcH_HpaI PF03328.14 KFH40535.1 - 1.6e-42 145.2 0.1 3e-41 141.0 0.0 2.0 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KFH40535.1 - 9.3e-11 41.5 0.0 2.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Hep_59 PF07052.11 KFH40537.1 - 1.6e-06 28.8 2.6 1.7e-06 28.7 0.0 2.2 2 2 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Tyosinase_C PF18132.1 KFH40537.1 - 0.082 13.6 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Tyosinase C-terminal domain Lactamase_B_3 PF13483.6 KFH40538.1 - 9.2e-07 28.9 0.2 2e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KFH40538.1 - 0.0014 18.1 0.3 0.0026 17.3 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RRM_1 PF00076.22 KFH40539.1 - 2.4e-23 81.7 0.0 3.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH40539.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFH40539.1 - 0.035 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PAP_PilO PF06864.12 KFH40539.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) RRM_3 PF08777.11 KFH40539.1 - 0.088 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.11 KFH40539.1 - 0.9 10.3 12.0 1.4 9.6 12.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family EF-hand_1 PF00036.32 KFH40540.1 - 1.2e-25 87.1 9.7 1e-06 27.8 0.2 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFH40540.1 - 7.6e-22 75.3 8.7 5e-05 22.9 0.2 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFH40540.1 - 9.8e-22 77.2 7.4 8.7e-10 38.9 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFH40540.1 - 3.1e-16 58.1 6.2 0.00029 20.2 0.5 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFH40540.1 - 3.7e-16 58.7 13.8 6.2e-09 35.6 0.1 5.0 2 2 3 5 5 5 4 EF-hand domain pair GUN4 PF05419.12 KFH40540.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.5 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.7 KFH40540.1 - 1.6 8.7 3.1 7.7 6.5 0.0 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand DIOX_N PF14226.6 KFH40543.1 - 1.6e-19 70.8 0.0 3.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH40543.1 - 1.3e-14 54.5 0.0 2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lactonase PF10282.9 KFH40544.1 - 3.1e-78 263.4 0.0 4.1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GMC_oxred_N PF00732.19 KFH40546.1 - 3.1e-54 184.3 0.0 4.4e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH40546.1 - 8.5e-33 113.9 0.0 1.3e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DIOX_N PF14226.6 KFH40547.1 - 1.8e-28 99.7 0.0 3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH40547.1 - 1.6e-13 51.0 0.0 2.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Trypsin PF00089.26 KFH40548.1 - 1.7e-09 37.8 0.0 2.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFH40548.1 - 2.3e-06 28.6 0.1 4.1e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain AMP_N PF05195.16 KFH40548.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain FA_desaturase PF00487.24 KFH40550.1 - 2e-13 50.8 28.3 2e-13 50.8 28.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase NAD_binding_1 PF00175.21 KFH40551.1 - 1.2e-11 45.3 0.0 3.4e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KFH40551.1 - 1.4e-08 35.2 0.2 6.8e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KFH40551.1 - 0.00019 21.7 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFH40551.1 - 0.00027 21.1 0.0 0.00085 19.5 0.0 1.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KFH40551.1 - 0.00054 19.9 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 Protoglobin RNA_pol_Rpb8 PF03870.15 KFH40551.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb8 Sulfotransfer_4 PF17784.1 KFH40552.1 - 1.9e-34 119.4 0.0 2.4e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH40552.1 - 4.2e-05 24.0 0.1 6.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 KFH40553.1 - 4.4e-21 75.2 39.0 4.4e-21 75.2 39.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH40553.1 - 1.5e-07 30.6 18.6 1.5e-06 27.4 18.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 KFH40553.1 - 6.9e-05 21.7 2.9 6.9e-05 21.7 2.9 1.9 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like Aldedh PF00171.22 KFH40554.1 - 1.2e-05 24.1 0.0 1.3e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 KFH40555.1 - 6.3e-60 203.2 0.0 8.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hva1_TUDOR PF11160.8 KFH40556.1 - 2.9e-15 56.2 2.2 3.7e-15 55.8 2.2 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CorA PF01544.18 KFH40557.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FAM209 PF15206.6 KFH40557.1 - 0.049 13.4 0.9 0.12 12.1 0.0 1.8 1 1 1 2 2 2 0 FAM209 family Sulfotransfer_4 PF17784.1 KFH40558.1 - 1.2e-57 195.3 0.0 1.4e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH40558.1 - 3.2e-05 24.4 1.1 0.2 12.0 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Methyltransf_12 PF08242.12 KFH40559.1 - 1.5e-09 38.5 0.0 2.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH40559.1 - 3e-09 37.5 0.1 5.1e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40559.1 - 1.3e-08 35.4 0.0 2.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40559.1 - 3.9e-08 33.2 0.0 4.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH40559.1 - 2.3e-07 30.6 0.0 3.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH40559.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KFH40559.1 - 9e-05 22.4 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFH40559.1 - 0.0066 15.9 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 KFH40559.1 - 0.02 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KFH40559.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KFH40559.1 - 0.046 13.0 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 KFH40559.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase APH PF01636.23 KFH40560.1 - 2.5e-06 27.6 0.3 4.4e-06 26.8 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH40560.1 - 0.0097 15.3 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KFH40560.1 - 0.068 12.5 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 KFH40560.1 - 0.2 11.2 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase VSP PF03302.13 KFH40561.1 - 0.038 12.9 6.6 0.037 12.9 5.0 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein Asp PF00026.23 KFH40561.1 - 0.091 12.2 0.1 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic aspartyl protease Transferase PF02458.15 KFH40562.1 - 6.8e-25 87.6 0.0 4.8e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Transferase family Epimerase PF01370.21 KFH40563.1 - 3.5e-24 85.6 0.0 4.7e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH40563.1 - 2e-14 53.3 0.0 2.9e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFH40563.1 - 9.1e-13 48.0 0.0 5e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFH40563.1 - 4.2e-12 46.1 0.0 1.1e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFH40563.1 - 1e-10 41.8 0.0 5.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFH40563.1 - 9e-10 38.2 0.1 1.3e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFH40563.1 - 1.5e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH40563.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFH40563.1 - 0.00028 21.4 0.2 0.00075 20.0 0.1 1.7 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KFH40563.1 - 0.00052 19.6 0.1 0.012 15.2 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KFH40563.1 - 0.019 15.2 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFH40563.1 - 0.021 14.7 0.3 0.04 13.8 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFH40563.1 - 0.029 13.5 0.2 0.041 13.0 0.2 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 KFH40563.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KFH40563.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 KFH40563.1 - 0.064 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HET PF06985.11 KFH40564.1 - 1.6e-37 129.1 4.3 2.7e-37 128.3 4.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KFH40566.1 - 1.6e-51 175.5 0.0 1.8e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CUE PF02845.16 KFH40566.1 - 0.11 12.3 0.0 14 5.5 0.0 2.7 2 0 0 2 2 2 0 CUE domain LSM PF01423.22 KFH40567.1 - 1.4e-19 69.5 0.1 1.7e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KFH40567.1 - 0.00029 21.3 10.8 0.00044 20.8 10.8 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 KFH40567.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain GAT PF03127.14 KFH40568.1 - 9.4e-19 67.5 1.8 9.4e-19 67.5 1.8 2.1 3 0 0 3 3 3 1 GAT domain VHS PF00790.19 KFH40568.1 - 2.2e-05 24.3 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain PspA_IM30 PF04012.12 KFH40568.1 - 0.018 14.6 0.9 0.095 12.3 0.9 1.9 1 1 0 1 1 1 0 PspA/IM30 family LMBR1 PF04791.16 KFH40568.1 - 0.3 10.0 0.1 0.37 9.6 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pan3_PK PF18101.1 KFH40569.1 - 8.9e-59 197.4 0.3 1.5e-58 196.7 0.3 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFH40569.1 - 2e-07 30.7 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFH40569.1 - 0.0035 16.7 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 KFH40569.1 - 0.0067 16.3 0.8 0.012 15.5 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.15 KFH40569.1 - 0.11 12.2 1.4 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region E1-E2_ATPase PF00122.20 KFH40570.1 - 5.6e-38 130.3 11.6 1.5e-30 106.1 0.1 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH40570.1 - 4.5e-25 88.4 9.4 1.7e-24 86.5 9.4 2.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFH40570.1 - 1.2e-19 71.4 0.0 4.6e-16 59.8 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH40570.1 - 2e-17 63.1 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFH40570.1 - 2.7e-16 59.0 0.4 8.2e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH40570.1 - 0.16 11.7 0.1 0.57 9.9 0.2 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KFH40571.1 - 0.062 13.2 0.1 0.31 10.9 0.1 2.3 1 1 0 1 1 1 0 F-box-like UBA_4 PF14555.6 KFH40573.1 - 6.7e-12 45.0 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFH40573.1 - 1.4e-07 31.6 0.0 3.7e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 UBX domain SUB1_ProdP9 PF18213.1 KFH40573.1 - 0.015 15.2 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF3530 PF12048.8 KFH40574.1 - 0.00074 19.0 1.3 0.00079 18.9 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Cupin_5 PF06172.11 KFH40575.1 - 3e-38 131.2 0.0 3.9e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Sporozoite_P67 PF05642.11 KFH40575.1 - 0.0045 15.2 0.6 0.0048 15.0 0.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Radial_spoke PF04712.12 KFH40575.1 - 0.07 12.1 10.1 0.08 11.9 10.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 KFH40575.1 - 0.087 12.5 4.4 0.13 11.9 4.4 1.3 1 0 0 1 1 1 0 FAM176 family Pes-10 PF07149.11 KFH40575.1 - 0.12 11.4 9.6 0.15 11.1 9.6 1.1 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 KFH40575.1 - 0.14 11.5 9.3 0.17 11.2 9.3 1.1 1 0 0 1 1 1 0 SDA1 Usp PF00582.26 KFH40575.1 - 0.27 11.7 2.1 0.41 11.2 2.1 1.4 1 0 0 1 1 1 0 Universal stress protein family CobT PF06213.12 KFH40575.1 - 0.7 9.2 11.8 1.1 8.6 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 KFH40575.1 - 0.77 9.0 10.1 1 8.6 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 KFH40575.1 - 0.9 8.5 14.5 1.1 8.1 14.5 1.1 1 0 0 1 1 1 0 Paf1 RNA_pol_3_Rpc31 PF11705.8 KFH40575.1 - 3.9 7.7 15.4 5.6 7.2 15.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4637 PF15470.6 KFH40575.1 - 4.1 7.1 14.7 6.2 6.5 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 KFH40575.1 - 4.6 5.3 15.1 5.8 5.0 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KFH40575.1 - 4.6 6.6 13.3 6.1 6.2 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HSP90 PF00183.18 KFH40575.1 - 6 5.6 10.7 7.6 5.3 10.7 1.1 1 0 0 1 1 1 0 Hsp90 protein RPN2_C PF18004.1 KFH40575.1 - 7.1 6.5 8.8 10 6.0 8.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 KFH40575.1 - 8.9 4.3 19.5 12 3.9 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 KFH40577.1 - 0.00054 20.0 10.4 0.00098 19.2 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PADR1 PF08063.12 KFH40577.1 - 0.1 12.4 2.3 0.23 11.3 2.3 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain Ank_2 PF12796.7 KFH40578.1 - 5.8e-22 78.1 0.2 4.7e-08 33.5 0.1 5.9 2 2 5 7 7 7 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 KFH40578.1 - 3.9e-19 69.1 0.0 9.2e-19 67.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.6 KFH40578.1 - 7.4e-19 67.9 6.8 1.3e-07 32.0 0.1 7.2 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH40578.1 - 2.1e-17 62.9 2.8 4.9e-06 26.7 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH40578.1 - 7.7e-16 56.6 4.9 0.001 19.3 0.1 8.7 9 0 0 9 9 9 3 Ankyrin repeat Pkinase_Tyr PF07714.17 KFH40578.1 - 5.9e-14 52.0 0.0 9.8e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KFH40578.1 - 1.5e-11 44.2 6.4 0.32 11.5 0.4 8.3 9 0 0 9 9 9 5 Ankyrin repeat Kdo PF06293.14 KFH40578.1 - 0.04 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFH40578.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LysM PF01476.20 KFH40579.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain Pet191_N PF10203.9 KFH40579.1 - 0.52 10.7 3.0 2.7 8.3 0.2 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 HeLo PF14479.6 KFH40580.1 - 1.6e-25 90.2 2.1 4.8e-25 88.6 1.1 2.0 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.25 KFH40580.1 - 0.04 13.3 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein kinase domain CdvA PF18822.1 KFH40581.1 - 0.12 12.2 0.3 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain p450 PF00067.22 KFH40582.1 - 1.6e-44 152.4 0.0 2.1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MIF4G PF02854.19 KFH40583.1 - 9.8e-54 182.2 0.0 1.7e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFH40583.1 - 6.1e-23 80.8 1.2 1.5e-22 79.5 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.12 KFH40583.1 - 0.16 12.4 0.0 0.57 10.6 0.0 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain eIF-5_eIF-2B PF01873.17 KFH40585.1 - 3.3e-40 136.6 0.0 8.5e-40 135.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KFH40585.1 - 1.1e-21 76.8 0.2 1.1e-21 76.8 0.2 2.2 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_pol_B PF00136.21 KFH40586.1 - 5.2e-114 381.5 0.3 7.4e-114 381.0 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KFH40586.1 - 3.4e-71 238.8 0.1 6.1e-71 238.0 0.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KFH40586.1 - 7.6e-44 150.2 0.1 2.1e-43 148.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KFH40586.1 - 4.6e-25 87.5 10.7 2.1e-24 85.4 10.7 2.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KFH40586.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Aquarius_N PF16399.5 KFH40587.1 - 0 1093.7 0.0 0 1093.4 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFH40587.1 - 1e-21 77.5 0.0 2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH40587.1 - 5e-21 75.7 0.0 4.7e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH40587.1 - 2.1e-07 30.9 0.1 0.00059 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KFH40587.1 - 3e-06 27.4 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFH40587.1 - 7.6e-06 26.3 0.0 1.8e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH40587.1 - 0.0015 19.0 0.0 0.006 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KFH40587.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 KFH40587.1 - 0.0028 18.1 0.0 0.0062 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KFH40587.1 - 0.029 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFH40587.1 - 0.039 14.2 0.1 0.24 11.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KFH40587.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_27 PF13514.6 KFH40587.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFH40587.1 - 0.19 12.1 0.0 0.52 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KFH40587.1 - 0.2 10.8 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase efThoc1 PF11957.8 KFH40588.1 - 1.1e-130 436.6 1.1 1.5e-130 436.2 1.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KFH40588.1 - 1.1e-32 113.2 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KFH40588.1 - 1.5e-05 25.4 0.0 4.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFH40588.1 - 0.00015 21.9 0.0 0.00037 20.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KFH40588.1 - 0.00033 21.2 0.2 0.0014 19.2 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KFH40588.1 - 0.00052 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFH40588.1 - 0.00076 19.7 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFH40588.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 KFH40588.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFH40588.1 - 0.0037 17.5 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFH40588.1 - 0.017 15.7 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KFH40588.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFH40588.1 - 0.018 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFH40588.1 - 0.019 15.4 0.2 0.53 10.7 0.2 3.3 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 KFH40588.1 - 0.025 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFH40588.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KFH40588.1 - 0.03 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KFH40588.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KFH40588.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFH40588.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KFH40588.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KFH40588.1 - 0.05 12.8 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KFH40588.1 - 0.057 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KFH40588.1 - 0.059 13.1 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KFH40588.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain P5CR_dimer PF14748.6 KFH40589.1 - 1.1e-32 112.3 1.0 1.1e-32 112.3 1.0 1.9 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFH40589.1 - 3e-18 66.2 2.7 3.2e-18 66.1 1.5 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFH40589.1 - 0.0051 17.0 0.2 0.0089 16.2 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KFH40589.1 - 0.12 12.8 0.2 0.31 11.5 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KFH40589.1 - 0.16 11.9 4.1 0.28 11.1 2.0 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SAB PF04382.13 KFH40590.1 - 0.024 14.7 0.1 0.078 13.1 0.1 1.8 1 0 0 1 1 1 0 SAB domain Phage_holin_5_1 PF06946.11 KFH40591.1 - 0.2 12.1 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 DUF563 PF04577.14 KFH40592.1 - 2.5e-33 116.0 0.0 4.3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SnoaL PF07366.12 KFH40593.1 - 0.00031 20.5 0.1 0.00099 18.9 0.0 1.9 3 0 0 3 3 3 1 SnoaL-like polyketide cyclase SLT PF01464.20 KFH40595.1 - 8.3e-11 41.6 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Bys1 PF04681.12 KFH40596.1 - 1.6e-12 47.6 0.0 1.9e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein PCuAC PF04314.13 KFH40596.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Copper chaperone PCu(A)C GED PF02212.18 KFH40598.1 - 0.032 14.4 1.0 0.064 13.4 0.4 1.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain Vps39_2 PF10367.9 KFH40599.1 - 3.7e-06 27.3 0.0 9.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFH40599.1 - 0.0017 18.6 0.1 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 PS_Dcarbxylase PF02666.15 KFH40600.1 - 6.1e-78 261.0 0.0 2e-76 256.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KFH40600.1 - 0.21 11.5 0.5 0.4 10.5 0.5 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like FAD_binding_1 PF00667.20 KFH40601.1 - 1.2e-43 149.2 0.0 2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFH40601.1 - 1.2e-09 38.8 0.0 4.6e-09 36.9 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3455 PF11937.8 KFH40603.1 - 1e-39 136.5 0.1 1.4e-39 136.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KFH40603.1 - 0.0041 17.2 0.5 0.0098 16.0 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2990) Methyltransf_16 PF10294.9 KFH40604.1 - 4.9e-11 42.7 0.0 6.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KFH40604.1 - 0.0021 17.5 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2 PF00096.26 KFH40605.1 - 1e-05 25.7 17.0 0.27 11.8 0.5 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type Pox_G9-A16 PF03003.16 KFH40605.1 - 0.013 15.2 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 DUF2407 PF10302.9 KFH40606.1 - 0.0001 22.8 0.1 0.00047 20.7 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KFH40606.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KFH40606.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2530 PF10745.9 KFH40606.1 - 0.22 11.8 1.5 0.53 10.5 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Ribosomal_L22 PF00237.19 KFH40607.1 - 7.7e-40 135.3 0.1 1e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CASP_C PF08172.12 KFH40608.1 - 2.3e-96 322.0 0.0 2.3e-96 322.0 0.0 3.4 4 0 0 4 4 4 1 CASP C terminal bZIP_2 PF07716.15 KFH40608.1 - 0.0075 16.3 5.9 0.0075 16.3 5.9 8.7 10 1 0 10 10 10 2 Basic region leucine zipper DUF4407 PF14362.6 KFH40608.1 - 0.051 12.9 36.2 0.47 9.7 1.1 4.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KFH40608.1 - 0.091 11.7 0.0 0.091 11.7 0.0 3.2 2 1 0 2 2 2 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 KFH40608.1 - 0.26 11.3 72.0 0.17 11.9 2.6 7.2 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFH40608.1 - 3 8.2 51.7 0.054 13.9 3.3 4.5 1 1 2 4 4 4 0 Fez1 UPF0242 PF06785.11 KFH40608.1 - 8.5 6.4 52.1 6.6 6.8 3.0 5.8 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Fibrillarin PF01269.17 KFH40609.1 - 6.5e-99 329.6 0.0 8.1e-99 329.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KFH40609.1 - 6.9e-07 29.2 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFH40609.1 - 0.0052 16.6 0.1 0.008 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KFH40609.1 - 0.049 13.3 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F 2-Hacid_dh_C PF02826.19 KFH40610.1 - 1.3e-45 155.0 0.0 1.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH40610.1 - 8.2e-05 22.3 0.0 0.00011 21.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KFH40610.1 - 0.051 13.7 0.0 0.17 12.0 0.0 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KFH40610.1 - 0.086 13.4 0.0 0.77 10.3 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain ELFV_dehydrog PF00208.21 KFH40610.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KFH40610.1 - 0.14 12.6 0.0 0.48 10.9 0.0 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Scytalone_dh PF02982.14 KFH40611.1 - 4.7e-44 150.0 0.1 5.4e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KFH40611.1 - 5.7e-07 29.7 0.0 7.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Bac_DnaA_C PF08299.11 KFH40611.1 - 0.19 11.8 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Xan_ur_permease PF00860.20 KFH40612.1 - 8.4e-25 87.3 30.9 3e-15 55.8 12.5 2.9 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.20 KFH40612.1 - 6.2e-05 21.9 17.9 0.00012 21.0 3.4 3.1 2 1 1 3 3 3 2 Sulfate permease family DUF4956 PF16316.5 KFH40612.1 - 7.7 6.2 11.0 1.4 8.5 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4956) Ank_2 PF12796.7 KFH40613.1 - 8.7e-12 45.5 0.0 1.6e-08 35.0 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH40613.1 - 6e-10 39.2 1.0 3.6e-05 23.9 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.12 KFH40613.1 - 1.6e-09 37.9 0.1 4.6e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KFH40613.1 - 1.6e-09 38.1 0.4 0.00019 21.9 0.2 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 KFH40613.1 - 1.1e-07 32.2 0.1 4.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH40613.1 - 4e-05 24.1 0.0 0.00016 22.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 KFH40613.1 - 0.00085 19.6 0.6 5.9 7.8 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KFH40613.1 - 0.0084 16.5 1.1 10 6.8 0.1 4.9 4 1 1 5 5 5 1 Ankyrin repeat KAP_NTPase PF07693.14 KFH40613.1 - 0.046 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain TrwB_AAD_bind PF10412.9 KFH40613.1 - 0.058 12.3 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain LAGLIDADG_3 PF14528.6 KFH40613.1 - 0.13 12.6 0.0 11 6.4 0.0 2.8 2 0 0 2 2 2 0 LAGLIDADG-like domain DIOX_N PF14226.6 KFH40616.1 - 0.00011 23.0 0.0 0.00019 22.2 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH40616.1 - 0.0053 17.2 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2397 PF09660.10 KFH40616.1 - 0.09 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3915 PF13054.6 KFH40618.1 - 2.3 8.2 11.6 4.8 7.2 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Rhomboid PF01694.22 KFH40619.1 - 7.6e-20 71.4 13.9 2.5e-19 69.8 11.7 2.1 2 0 0 2 2 2 1 Rhomboid family NADH-u_ox-rdase PF10785.9 KFH40619.1 - 0.13 12.9 0.8 0.36 11.5 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF1751 PF08551.10 KFH40619.1 - 0.15 12.7 0.0 0.48 11.0 0.0 2.0 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Sigma70_ner PF04546.13 KFH40619.1 - 0.21 11.4 7.7 0.13 12.2 5.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region HDV_ag PF01517.18 KFH40619.1 - 6.2 6.6 8.5 0.44 10.3 2.8 1.8 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Glyco_hydro_43 PF04616.14 KFH40621.1 - 4.5e-11 42.6 2.9 1.1e-10 41.3 2.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Polysacc_deac_1 PF01522.21 KFH40622.1 - 4e-18 65.5 0.0 5.7e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase OppC_N PF12911.7 KFH40622.1 - 0.00066 19.6 1.0 0.0015 18.4 1.0 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Polysacc_deac_2 PF04748.13 KFH40622.1 - 0.056 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase LSM PF01423.22 KFH40623.1 - 1.1e-21 76.3 0.1 1.2e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFH40623.1 - 6.4e-05 23.0 0.1 7.7e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFH40623.1 - 0.0012 18.8 0.1 0.0015 18.6 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KFH40623.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Hfq protein GspL_C PF12693.7 KFH40625.1 - 0.098 12.5 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 GspL periplasmic domain FixQ PF05545.11 KFH40626.1 - 0.54 10.3 0.1 0.54 10.3 0.1 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Cys_Met_Meta_PP PF01053.20 KFH40627.1 - 2.2e-59 200.9 0.0 5e-59 199.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFH40627.1 - 0.085 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3801 PF12687.7 KFH40628.1 - 0.016 15.3 0.7 0.027 14.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) SlyX PF04102.12 KFH40628.1 - 3 8.5 7.3 75 4.1 2.1 3.6 3 1 0 3 3 3 0 SlyX SIR2 PF02146.17 KFH40630.1 - 4e-24 85.5 0.0 1.2e-23 84.0 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFH40630.1 - 0.098 12.4 0.1 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CTP_transf_like PF01467.26 KFH40630.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase-like Rad60-SLD PF11976.8 KFH40631.1 - 2.2e-14 53.0 1.4 2.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFH40631.1 - 0.00052 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 KFH40632.1 - 1.1e-11 45.3 0.1 5.4e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH40632.1 - 4.1e-09 37.0 0.1 1.3e-08 35.4 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40632.1 - 4.3e-06 26.7 0.0 7.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40632.1 - 4.9e-06 26.4 0.0 3.1e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40632.1 - 1.4e-05 25.7 0.0 3.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH40632.1 - 0.00084 18.7 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFH40632.1 - 0.015 14.9 0.0 0.073 12.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 KFH40632.1 - 0.02 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 KFH40632.1 - 0.08 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase IU_nuc_hydro PF01156.19 KFH40633.1 - 5e-59 200.3 0.0 8.1e-59 199.7 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PVL_ORF50 PF07768.11 KFH40634.1 - 0.012 15.9 1.6 0.012 15.9 1.6 2.3 2 0 0 2 2 2 0 PVL ORF-50-like family Blt1 PF12754.7 KFH40634.1 - 0.15 12.3 1.9 0.28 11.5 1.1 1.8 2 0 0 2 2 2 0 Blt1 N-terminal domain DUF768 PF05589.11 KFH40635.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF768) FAD_binding_3 PF01494.19 KFH40637.1 - 1.6e-06 27.6 2.6 5e-06 26.0 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Leo1 PF04004.13 KFH40637.1 - 0.14 12.0 0.2 0.3 10.9 0.2 1.6 1 1 0 1 1 1 0 Leo1-like protein CMD PF02627.20 KFH40638.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family ketoacyl-synt PF00109.26 KFH40639.1 - 6.7e-61 206.1 0.0 1.2e-60 205.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH40639.1 - 2.4e-59 200.3 0.0 7.2e-59 198.7 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH40639.1 - 5.2e-41 140.8 0.1 8.3e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH40639.1 - 4.6e-40 138.1 0.0 1.1e-39 136.8 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH40639.1 - 4e-38 130.1 0.0 8.4e-38 129.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH40639.1 - 1.2e-15 58.0 0.0 3.1e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH40639.1 - 8.8e-15 55.1 0.0 3.7e-14 53.1 0.0 2.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KFH40639.1 - 1.5e-12 47.7 0.0 3.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH40639.1 - 1.6e-10 40.8 0.0 5.4e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFH40639.1 - 2.5e-10 40.9 0.0 8.4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40639.1 - 5.5e-09 36.0 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40639.1 - 7.5e-09 36.1 0.0 2.3e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KFH40639.1 - 1.4e-07 31.5 2.6 1.7e-07 31.2 0.2 2.4 3 0 0 3 3 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KFH40639.1 - 8.3e-07 29.3 0.0 2.7e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFH40639.1 - 1.9e-05 24.1 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KFH40639.1 - 0.0071 16.2 1.1 0.019 14.8 0.2 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.21 KFH40639.1 - 0.032 13.7 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH40639.1 - 0.1 11.9 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_PK PF05891.12 KFH40639.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 KFH40639.1 - 0.13 12.0 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.23 KFH40639.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Mga PF05043.13 KFH40639.1 - 0.19 12.3 0.0 0.41 11.3 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain F-box PF00646.33 KFH40640.1 - 0.025 14.5 0.4 0.038 13.9 0.4 1.2 1 0 0 1 1 1 0 F-box domain GMC_oxred_N PF00732.19 KFH40641.1 - 2.3e-57 194.7 0.1 3.5e-57 194.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH40641.1 - 4.1e-27 95.5 0.1 8.3e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFH40641.1 - 8.1e-05 21.8 0.1 0.00016 20.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFH40641.1 - 0.00033 19.9 1.8 0.29 10.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFH40641.1 - 0.0022 17.7 1.7 0.36 10.4 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFH40641.1 - 0.0036 16.6 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFH40641.1 - 0.0066 16.7 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFH40641.1 - 0.017 14.4 0.1 3 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KFH40641.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HET PF06985.11 KFH40643.1 - 8.7e-24 84.5 0.0 1.1e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PHtD_u1 PF16645.5 KFH40643.1 - 0.16 12.4 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Zn_ribbon_SprT PF17283.2 KFH40644.1 - 0.023 14.6 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain BBS2_N PF14781.6 KFH40644.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal AAA_18 PF13238.6 KFH40644.1 - 0.18 12.3 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KFH40645.1 - 4.6e-33 114.7 1.0 1.7e-17 63.3 0.0 2.6 1 1 3 4 4 4 2 Cytochrome P450 DUF2561 PF10812.8 KFH40645.1 - 0.95 9.5 6.6 0.11 12.6 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Sulfotransfer_4 PF17784.1 KFH40646.1 - 1.6e-56 191.5 0.0 2e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Virulence_fact PF13769.6 KFH40646.1 - 0.033 14.4 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 Virulence factor Sulfotransfer_3 PF13469.6 KFH40646.1 - 0.035 14.5 0.1 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase family p450 PF00067.22 KFH40647.1 - 9.3e-27 93.9 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KFH40648.1 - 1.9e-51 175.2 0.0 2.5e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH40648.1 - 1.7e-32 112.9 0.0 2.5e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFH40648.1 - 0.00089 18.4 0.3 0.00089 18.4 0.3 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein DUF3953 PF13129.6 KFH40649.1 - 0.061 13.1 0.7 0.061 13.1 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) Secretin_N_2 PF07655.13 KFH40649.1 - 2.4 8.7 11.9 4 8.0 11.9 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain p450 PF00067.22 KFH40650.1 - 1.6e-56 192.0 0.0 2.1e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipid_bd PF12888.7 KFH40650.1 - 0.16 12.4 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipid-binding putative hydrolase YrvL PF14184.6 KFH40653.1 - 0.056 13.6 0.6 0.16 12.1 0.6 1.7 1 0 0 1 1 1 0 Regulatory protein YrvL HET PF06985.11 KFH40656.1 - 1.1e-19 71.3 0.0 1.9e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.22 KFH40657.1 - 2.1e-39 134.7 0.0 3.3e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH40657.1 - 1.4e-11 44.7 0.0 2.9e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH40657.1 - 0.003 17.0 0.0 0.0087 15.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH40657.1 - 0.0046 17.0 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 KFH40657.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Peptidase_M28 PF04389.17 KFH40658.1 - 2.9e-35 121.8 0.0 4.1e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH40658.1 - 1.5e-14 53.7 0.3 3.3e-14 52.7 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFH40658.1 - 2.7e-06 27.2 0.0 1.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Pyridoxal_deC PF00282.19 KFH40659.1 - 2.1e-78 263.7 0.0 3.2e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFH40659.1 - 7e-06 25.2 0.0 1.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFH40659.1 - 3.3e-05 23.3 1.2 3.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase TMPIT PF07851.13 KFH40660.1 - 0.019 14.2 0.3 0.025 13.8 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein YABBY PF04690.13 KFH40660.1 - 0.052 14.1 0.7 0.068 13.7 0.7 1.2 1 0 0 1 1 1 0 YABBY protein PUF PF00806.19 KFH40661.1 - 3.1e-11 42.3 0.1 1.4 8.7 0.0 6.7 6 1 1 7 7 7 5 Pumilio-family RNA binding repeat DDHD PF02862.17 KFH40661.1 - 5 7.2 8.1 40 4.3 5.3 3.0 3 0 0 3 3 3 0 DDHD domain AMMECR1 PF01871.17 KFH40662.1 - 5.9e-45 152.9 0.0 6.7e-45 152.7 0.0 1.2 1 1 0 1 1 1 1 AMMECR1 TALPID3 PF15324.6 KFH40662.1 - 0.017 12.8 3.1 0.021 12.6 3.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target AstE_AspA PF04952.14 KFH40663.1 - 0.1 11.7 0.8 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family PepSY_TM_like_2 PF16357.5 KFH40663.1 - 0.21 11.6 0.1 0.58 10.1 0.1 1.7 1 1 1 2 2 2 0 Putative PepSY_TM-like Herpes_UL32 PF06070.11 KFH40663.1 - 0.43 8.3 5.1 0.7 7.6 5.1 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HNH PF01844.23 KFH40664.1 - 0.0058 16.8 1.0 0.015 15.5 1.0 1.7 1 1 0 1 1 1 1 HNH endonuclease Cas3_C PF18395.1 KFH40664.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Cas3 C-terminal domain SIT PF15330.6 KFH40665.1 - 0.088 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Phage_HK97_TLTM PF06120.11 KFH40665.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Glyco_hydro_12 PF01670.16 KFH40667.1 - 2.6e-25 89.7 0.7 3e-25 89.5 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 tRNA-synt_2 PF00152.20 KFH40668.1 - 3.8e-60 203.6 0.0 8.3e-50 169.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KFH40668.1 - 1.6e-05 24.5 0.0 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KFH40668.1 - 0.00029 20.8 0.0 0.0072 16.3 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Actin PF00022.19 KFH40669.1 - 1.3e-148 495.0 0.0 1.4e-148 494.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFH40669.1 - 0.00077 18.4 0.0 0.89 8.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.12 KFH40670.1 - 1e-50 170.7 0.1 1.3e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KFH40670.1 - 0.16 12.3 10.2 0.28 11.5 10.2 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BNIP3 PF06553.12 KFH40670.1 - 0.89 9.2 3.2 1.7 8.3 3.2 1.4 1 0 0 1 1 1 0 BNIP3 SMN PF06003.12 KFH40670.1 - 7.2 5.8 7.7 11 5.2 7.7 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3752 PF12572.8 KFH40671.1 - 4.6e-44 150.6 7.9 4.6e-44 150.6 7.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Raffinose_syn PF05691.12 KFH40672.1 - 6.2e-53 179.7 0.5 5.1e-42 143.6 0.0 3.4 3 1 1 4 4 4 3 Raffinose synthase or seed imbibition protein Sip1 ocr PF08684.10 KFH40672.1 - 0.0017 18.8 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 DNA mimic ocr Melibiase PF02065.18 KFH40672.1 - 0.013 14.4 0.2 0.022 13.7 0.2 1.3 1 0 0 1 1 1 0 Melibiase zf-RING_2 PF13639.6 KFH40673.1 - 6.3e-12 45.6 6.0 9.9e-12 45.0 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFH40673.1 - 3.7e-08 33.0 0.6 6.5e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFH40673.1 - 3.9e-08 33.0 5.7 6.3e-08 32.3 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH40673.1 - 5.8e-08 32.5 3.2 9.7e-08 31.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH40673.1 - 7.6e-07 29.3 7.8 2e-06 28.0 7.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFH40673.1 - 5.8e-06 26.2 3.4 9.4e-06 25.5 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH40673.1 - 0.001 19.1 0.8 0.001 19.1 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFH40673.1 - 0.0016 18.3 2.2 0.0027 17.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFH40673.1 - 0.002 18.2 4.3 0.0048 16.9 4.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFH40673.1 - 0.053 13.3 6.3 0.094 12.5 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFH40673.1 - 0.08 12.8 3.7 0.18 11.7 3.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HNF-1_N PF04814.13 KFH40673.1 - 0.13 12.8 6.6 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PHD PF00628.29 KFH40673.1 - 0.18 11.7 5.6 0.32 10.9 5.6 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KFH40673.1 - 0.28 10.8 4.2 0.49 10.0 4.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFH40673.1 - 0.35 11.1 4.0 0.73 10.0 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFH40673.1 - 0.48 10.6 2.6 1.5 9.1 2.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain OAD_gamma PF04277.13 KFH40673.1 - 0.99 10.0 0.0 0.99 10.0 0.0 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Pyr_redox_2 PF07992.14 KFH40674.1 - 3.3e-51 174.3 1.8 4e-51 174.0 1.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH40674.1 - 1.3e-18 67.3 1.3 6e-16 58.8 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH40674.1 - 2.5e-18 66.4 0.6 1.3e-16 60.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFH40674.1 - 1.1e-05 25.8 0.1 0.0051 17.2 0.1 2.7 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFH40674.1 - 1.7e-05 25.0 0.1 0.034 14.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH40674.1 - 0.00024 20.4 0.0 0.00085 18.6 0.0 1.9 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFH40674.1 - 0.00037 20.0 0.6 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KFH40674.1 - 0.00045 19.9 5.6 0.21 11.2 0.0 3.6 2 2 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFH40674.1 - 0.001 18.3 0.9 0.28 10.3 0.1 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KFH40674.1 - 0.0051 16.9 0.6 4.8 7.2 0.1 3.2 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFH40674.1 - 0.0095 15.2 1.3 2.3 7.4 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 KFH40674.1 - 0.023 13.8 6.5 0.74 8.8 0.1 4.0 3 2 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFH40674.1 - 0.026 14.5 0.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFH40674.1 - 0.034 12.8 0.1 1.7 7.3 0.0 2.7 2 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KFH40674.1 - 0.036 13.2 3.6 0.51 9.4 2.5 2.9 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFH40674.1 - 0.08 11.8 0.1 0.42 9.4 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase UDG PF03167.19 KFH40675.1 - 9.6e-20 71.1 0.1 5e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily FSA_C PF10479.9 KFH40675.1 - 0.77 7.8 3.8 1 7.4 3.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DEAD PF00270.29 KFH40676.1 - 1.9e-26 92.9 0.2 1.2e-25 90.3 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH40676.1 - 1.7e-22 79.9 0.0 4.1e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH40676.1 - 0.0001 22.4 0.2 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps8 PF12816.7 KFH40677.1 - 2.4e-75 252.4 0.0 4.6e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFH40677.1 - 4.1e-05 23.5 0.1 0.011 15.6 0.0 3.5 4 0 0 4 4 4 1 Region in Clathrin and VPS zf-RING_UBOX PF13445.6 KFH40677.1 - 0.0025 17.8 0.1 0.0059 16.6 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH40677.1 - 0.0074 16.6 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFH40677.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain K_channel_TID PF07941.11 KFH40677.1 - 0.012 16.0 8.1 0.042 14.3 8.1 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-rbx1 PF12678.7 KFH40677.1 - 0.025 14.9 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFH40677.1 - 0.043 13.7 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KFH40677.1 - 0.062 13.2 0.3 0.21 11.5 0.3 1.9 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KFH40677.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KFH40677.1 - 0.16 12.0 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 KFH40677.1 - 0.33 10.7 2.7 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 RING-like zinc finger Vps53_N PF04100.12 KFH40678.1 - 8.6e-103 344.2 0.2 1.4e-102 343.5 0.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KFH40678.1 - 3.6e-06 26.5 5.9 6.9e-06 25.5 5.9 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 KFH40678.1 - 2.4e-05 23.4 1.2 0.02 13.8 0.0 2.9 3 0 0 3 3 3 2 RINT-1 / TIP-1 family DUF2451 PF10474.9 KFH40678.1 - 0.0002 21.3 0.1 0.00047 20.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF1664 PF07889.12 KFH40678.1 - 0.019 15.0 1.5 0.053 13.5 1.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Zw10 PF06248.13 KFH40678.1 - 0.021 13.4 6.1 0.024 13.2 4.7 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 KFH40678.1 - 0.066 12.1 3.9 0.11 11.4 3.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KFH40678.1 - 0.083 12.2 7.1 0.16 11.2 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 KFH40678.1 - 0.093 13.0 3.6 0.4 11.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF3919 PF13057.6 KFH40678.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) IFT57 PF10498.9 KFH40678.1 - 0.13 11.2 2.4 0.26 10.2 2.4 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2939 PF11159.8 KFH40678.1 - 0.19 12.1 0.8 1.1 9.7 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2939) HIP1_clath_bdg PF16515.5 KFH40678.1 - 0.22 12.2 4.6 0.71 10.5 4.6 1.9 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COG5 PF10392.9 KFH40678.1 - 0.46 10.6 7.4 1 9.5 2.3 3.6 3 1 1 4 4 3 0 Golgi transport complex subunit 5 TetR_C_11 PF16859.5 KFH40678.1 - 0.94 9.8 3.4 4.6 7.6 0.0 3.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Baculo_PEP_C PF04513.12 KFH40678.1 - 1.7 8.7 4.9 3.7 7.6 4.5 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KFH40678.1 - 3.3 7.2 6.8 8 5.9 6.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Flagellin_N PF00669.20 KFH40678.1 - 6.3 6.9 8.8 0.78 9.8 1.2 2.7 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region COG2 PF06148.11 KFH40678.1 - 8.6 6.5 6.4 12 6.0 3.7 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2834 PF11196.8 KFH40679.1 - 1.4e-07 31.7 16.6 0.00081 19.7 0.5 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) WD40 PF00400.32 KFH40680.1 - 7.6e-22 77.2 2.9 1.7e-08 34.9 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40680.1 - 9.7e-14 51.4 0.0 0.0026 18.0 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFH40680.1 - 0.0013 17.8 0.0 0.073 12.1 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.8 KFH40680.1 - 0.0077 14.9 0.1 0.016 13.9 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KFH40680.1 - 0.047 13.3 0.0 0.78 9.3 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain RRM_1 PF00076.22 KFH40681.1 - 9.1e-17 60.6 0.0 1.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 KFH40681.1 - 0.0021 18.5 0.8 0.0039 17.6 0.8 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Nup35_RRM_2 PF14605.6 KFH40681.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFH40681.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 2 1 0 2 2 2 0 Occluded RNA-recognition motif MMPL PF03176.15 KFH40681.1 - 0.19 10.6 0.6 0.21 10.5 0.6 1.1 1 0 0 1 1 1 0 MMPL family Spc7 PF08317.11 KFH40681.1 - 0.2 10.5 5.2 0.24 10.2 5.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5089 PF17002.5 KFH40681.1 - 0.21 11.4 7.8 0.27 11.1 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) V_ATPase_I PF01496.19 KFH40681.1 - 0.24 9.3 3.3 0.26 9.1 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFH40681.1 - 0.25 10.4 1.3 0.32 10.0 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KFH40681.1 - 0.27 11.0 2.8 0.43 10.4 2.8 1.3 1 0 0 1 1 1 0 Septum formation initiator HAP1_N PF04849.13 KFH40681.1 - 0.27 10.4 10.0 0.35 10.0 10.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region EMP24_GP25L PF01105.24 KFH40681.1 - 0.29 11.1 3.3 0.4 10.6 3.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 KFH40681.1 - 0.43 11.0 6.8 0.76 10.3 6.5 1.5 1 1 0 1 1 1 0 Cell division protein ZapB CPSF100_C PF13299.6 KFH40681.1 - 0.43 10.7 5.2 0.55 10.4 5.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF724 PF05266.14 KFH40681.1 - 0.76 9.6 6.4 1.1 9.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 KFH40681.1 - 0.92 10.5 6.9 1.4 9.9 6.9 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 KFH40681.1 - 1.2 9.2 4.8 1.5 8.9 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mt_ATP-synt_D PF05873.12 KFH40681.1 - 2.2 8.1 6.5 3.1 7.6 6.5 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Oxidored_q6 PF01058.22 KFH40682.1 - 2.3e-22 79.2 0.0 3.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit RabGAP-TBC PF00566.18 KFH40683.1 - 2.5e-51 174.4 0.0 3.4e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KFH40684.1 - 7.1e-21 73.8 0.2 2.3e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH40684.1 - 2.4e-05 24.4 0.0 0.00091 19.3 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFH40684.1 - 0.009 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif IcmF_C PF06744.12 KFH40684.1 - 0.065 12.8 5.5 0.12 12.0 5.5 1.4 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal TFIIA PF03153.13 KFH40684.1 - 0.076 13.0 13.3 0.1 12.6 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 KFH40684.1 - 0.24 9.3 26.2 0.3 8.9 26.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1631 PF07793.11 KFH40684.1 - 8.6 4.6 11.3 12 4.2 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) p450 PF00067.22 KFH40685.1 - 3.7e-56 190.8 0.0 5.7e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SNF2_N PF00176.23 KFH40686.1 - 9.1e-75 251.5 0.3 2.2e-74 250.3 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFH40686.1 - 2.1e-41 140.5 1.8 2.1e-41 140.5 1.8 2.8 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KFH40686.1 - 5.9e-35 120.4 5.4 5.9e-35 120.4 5.4 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KFH40686.1 - 4.7e-19 68.8 1.0 3.1e-18 66.1 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH40686.1 - 4.1e-10 39.9 0.0 3.6e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFH40686.1 - 5.5e-08 32.3 0.0 1.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KFH40686.1 - 0.00012 21.9 0.0 0.00064 19.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFH40686.1 - 0.0014 17.9 0.3 0.0014 17.9 0.3 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KFH40686.1 - 0.0015 18.2 0.0 0.0056 16.4 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 KFH40686.1 - 0.072 13.3 0.3 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain DEAD_2 PF06733.15 KFH40686.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 RHH_6 PF16762.5 KFH40686.1 - 0.15 12.7 1.5 0.4 11.3 0.8 2.2 1 1 0 1 1 1 0 Ribbon-helix-helix domain Ion_trans PF00520.31 KFH40687.1 - 3.8e-08 32.9 1.5 5.1e-08 32.4 1.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKcGMP_CC PF16808.5 KFH40687.1 - 0.0089 15.9 1.6 0.019 14.8 1.6 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TolA_bind_tri PF16331.5 KFH40687.1 - 0.014 15.5 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation PKD_channel PF08016.12 KFH40687.1 - 0.015 14.0 0.8 0.022 13.5 0.8 1.3 1 0 0 1 1 1 0 Polycystin cation channel DivIC PF04977.15 KFH40687.1 - 0.016 15.0 1.0 0.031 14.0 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Mto2_bdg PF12808.7 KFH40687.1 - 0.037 14.3 0.4 0.069 13.5 0.4 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 KFH40687.1 - 0.046 13.9 0.3 0.07 13.3 0.3 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 KFH40687.1 - 0.079 13.1 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KFH40687.1 - 0.22 11.8 2.0 0.25 11.6 0.8 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper SUR7 PF06687.12 KFH40687.1 - 0.55 9.8 3.1 0.89 9.1 3.1 1.4 1 1 0 1 1 1 0 SUR7/PalI family HECT PF00632.25 KFH40688.1 - 5.4e-96 321.7 0.0 7.6e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFH40688.1 - 1.6e-34 117.6 20.2 1.1e-12 47.8 1.9 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFH40688.1 - 7.2e-20 71.2 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 KFH40688.1 - 2 6.8 10.9 2.9 6.3 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Glyco_transf_90 PF05686.12 KFH40689.1 - 9.6e-13 47.8 1.6 2.4e-11 43.2 0.0 2.9 2 2 0 2 2 2 2 Glycosyl transferase family 90 DUF4588 PF15251.6 KFH40690.1 - 1.4e-08 34.8 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) CD52 PF15116.6 KFH40692.1 - 6.5 6.9 6.3 1.1 9.3 1.0 2.6 3 0 0 3 3 3 0 CAMPATH-1 antigen MMU163 PF17119.5 KFH40693.1 - 1.2e-74 250.6 6.8 1.1e-72 244.1 6.8 2.0 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 KFH40693.1 - 0.7 10.0 0.1 0.7 10.0 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase RNase_PH PF01138.21 KFH40694.1 - 1.1e-12 48.6 0.0 1.8e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFH40694.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NUDIX PF00293.28 KFH40695.1 - 1.4e-17 63.9 0.7 1.7e-17 63.7 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 KFH40696.1 - 1.2e-62 210.1 0.0 4.9e-46 156.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH40696.1 - 1.2e-14 53.8 0.3 1.9e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KFH40696.1 - 1.6e-11 44.9 4.9 0.0011 19.4 0.0 4.9 4 2 2 6 6 4 2 AAA ATPase domain AAA_5 PF07728.14 KFH40696.1 - 1.5e-09 38.0 0.5 0.0045 17.0 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH40696.1 - 3.5e-08 33.8 0.1 0.0042 17.4 0.0 4.7 2 2 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KFH40696.1 - 1.1e-07 31.7 0.0 0.00094 19.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFH40696.1 - 9.3e-07 29.4 0.0 0.03 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFH40696.1 - 1.5e-06 28.4 0.0 0.00074 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFH40696.1 - 2e-06 28.1 0.0 0.0019 18.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFH40696.1 - 0.0001 22.7 0.0 0.074 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KFH40696.1 - 0.00015 21.1 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_17 PF13207.6 KFH40696.1 - 0.00017 22.1 0.0 1.4 9.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFH40696.1 - 0.00043 20.3 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFH40696.1 - 0.00053 20.0 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFH40696.1 - 0.00061 19.6 0.1 0.044 13.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFH40696.1 - 0.0007 19.0 0.1 0.23 10.8 0.0 2.9 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFH40696.1 - 0.00089 18.5 0.0 0.94 8.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 KFH40696.1 - 0.0012 18.8 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Cytidylate_kin2 PF13189.6 KFH40696.1 - 0.0013 18.9 0.1 0.082 13.0 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family Rad17 PF03215.15 KFH40696.1 - 0.0021 18.0 0.1 0.84 9.5 0.0 2.7 2 2 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KFH40696.1 - 0.0022 18.2 0.0 1.1 9.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFH40696.1 - 0.0034 16.7 0.2 0.03 13.6 0.0 2.7 3 1 1 4 4 4 1 Zeta toxin Thymidylate_kin PF02223.17 KFH40696.1 - 0.0035 17.0 0.0 0.052 13.2 0.1 2.4 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin PF02224.18 KFH40696.1 - 0.0058 16.4 0.1 0.98 9.1 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase ABC_tran PF00005.27 KFH40696.1 - 0.0063 17.0 0.0 0.53 10.8 0.0 2.9 3 0 0 3 3 2 1 ABC transporter SKI PF01202.22 KFH40696.1 - 0.0075 16.4 0.1 7.2 6.7 0.0 3.8 4 0 0 4 4 3 0 Shikimate kinase Sigma54_activ_2 PF14532.6 KFH40696.1 - 0.009 16.1 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KFH40696.1 - 0.015 15.2 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFH40696.1 - 0.021 14.4 0.0 1.5 8.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFH40696.1 - 0.022 14.3 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFH40696.1 - 0.022 14.5 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFH40696.1 - 0.05 13.4 2.1 0.45 10.3 0.0 2.9 3 1 1 4 4 4 0 AAA domain AAA_30 PF13604.6 KFH40696.1 - 0.059 13.1 0.0 15 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFH40696.1 - 0.083 12.8 0.0 15 5.4 0.0 2.6 2 1 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 KFH40696.1 - 0.088 12.5 0.0 0.61 9.8 0.0 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 KFH40696.1 - 0.11 11.9 0.0 20 4.6 0.0 2.9 3 0 0 3 3 2 0 Bacterial TniB protein NB-ARC PF00931.22 KFH40696.1 - 0.12 11.6 0.0 2.8 7.0 0.0 2.9 4 0 0 4 4 3 0 NB-ARC domain AAA_19 PF13245.6 KFH40696.1 - 0.13 12.6 0.1 9.3 6.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 KFH40696.1 - 0.14 12.2 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KFH40696.1 - 0.15 11.9 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Cytochrom_C PF00034.21 KFH40697.1 - 3.9e-13 50.3 0.1 5.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFH40697.1 - 1.1e-08 35.3 2.9 3.9e-08 33.5 2.9 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFH40697.1 - 0.0085 15.8 2.1 0.061 13.0 2.0 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KFH40697.1 - 0.12 13.0 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 KFH40697.1 - 0.15 11.6 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Fructosamin_kin PF03881.14 KFH40698.1 - 7.6e-74 248.5 0.0 8.9e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFH40698.1 - 2.6e-06 27.5 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFH40698.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 KFH40699.1 - 1.6e-19 70.3 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH40699.1 - 6.5e-09 35.4 0.0 3.8e-05 23.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KFH40699.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFH40699.1 - 0.025 13.9 0.0 21 4.3 0.0 3.0 3 0 0 3 3 3 0 Kinase-like Fe-S_biosyn PF01521.20 KFH40700.1 - 2.8e-19 69.3 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Presenilin PF01080.17 KFH40700.1 - 0.14 10.9 3.0 0.14 10.9 3.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KFH40700.1 - 0.29 9.8 8.6 0.31 9.7 8.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KFH40700.1 - 0.7 9.0 9.6 0.8 8.8 9.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Spt20 PF12090.8 KFH40700.1 - 1.2 8.7 14.6 1.5 8.3 14.6 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KFH40700.1 - 1.5 8.8 12.8 1.7 8.6 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFH40700.1 - 2.4 6.3 13.4 2.8 6.1 13.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 KFH40700.1 - 2.6 8.0 9.8 3.6 7.5 9.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CAP_N PF01213.19 KFH40701.1 - 0.92 8.9 3.0 1.2 8.5 3.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATE_C PF04377.15 KFH40703.1 - 5.9e-47 159.7 0.6 5.9e-47 159.7 0.6 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFH40703.1 - 1.5e-19 70.1 0.3 3.5e-19 69.0 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Snf7 PF03357.21 KFH40704.1 - 2.1e-36 125.1 11.9 2.6e-36 124.8 11.9 1.1 1 0 0 1 1 1 1 Snf7 RelA_SpoT PF04607.17 KFH40704.1 - 0.048 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins DELLA PF12041.8 KFH40704.1 - 0.15 12.0 1.8 6.9 6.6 0.1 2.8 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF1843 PF08898.10 KFH40704.1 - 0.68 10.5 5.9 3.4 8.3 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Dynamin_N PF00350.23 KFH40705.1 - 4.5e-31 108.2 0.0 8.7e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH40705.1 - 4.1e-24 85.3 0.0 1.4e-23 83.5 0.0 1.9 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KFH40705.1 - 0.00012 22.2 0.0 0.0011 19.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KFH40705.1 - 0.00059 19.9 0.1 0.0093 16.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_15 PF13175.6 KFH40705.1 - 0.0036 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFH40705.1 - 0.0096 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH40705.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFH40705.1 - 0.099 13.2 0.0 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DNA_binding_1 PF01035.20 KFH40706.1 - 1.7e-27 95.3 0.0 2.5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Dicty_REP PF05086.12 KFH40706.1 - 5.7 4.8 4.6 6.9 4.5 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_61 PF03443.14 KFH40707.1 - 7e-35 120.8 0.2 8.3e-35 120.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 KFH40707.1 - 0.039 14.4 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 MG2 domain DUF4469 PF14734.6 KFH40707.1 - 0.05 13.8 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DUF2235 PF09994.9 KFH40708.1 - 1.7e-59 201.6 0.0 2.7e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_M20 PF01546.28 KFH40709.1 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ANAPC4_WD40 PF12894.7 KFH40710.1 - 0.0004 20.6 0.0 0.056 13.7 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH40710.1 - 0.0015 17.2 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 YL1 PF05764.13 KFH40710.1 - 0.099 12.7 9.3 0.14 12.3 9.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KFH40710.1 - 0.24 9.7 10.3 0.33 9.2 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KFH40710.1 - 0.27 9.8 14.8 0.37 9.3 14.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YqfQ PF14181.6 KFH40710.1 - 0.38 11.0 1.9 0.61 10.3 1.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein Cwf_Cwc_15 PF04889.12 KFH40710.1 - 0.43 10.3 15.1 0.67 9.6 15.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KFH40710.1 - 2.6 6.2 12.1 3.4 5.8 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFH40710.1 - 2.7 7.3 14.0 3.7 6.9 14.0 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KFH40710.1 - 5.3 5.5 9.8 7.4 5.0 9.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 KFH40710.1 - 8.4 5.6 12.6 14 4.9 12.6 1.3 1 0 0 1 1 1 0 NOA36 protein mRNA_triPase PF02940.15 KFH40711.1 - 8.4e-54 182.6 0.2 1.6e-53 181.7 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_43 PF04616.14 KFH40712.1 - 5.2e-36 124.4 6.4 7.7e-36 123.9 6.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFH40712.1 - 2.6e-24 86.1 0.1 4.6e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Fe-ADH PF00465.19 KFH40713.1 - 4.1e-17 62.1 0.0 5.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFH40713.1 - 1.8e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Xan_ur_permease PF00860.20 KFH40714.1 - 3.3e-65 220.3 26.1 1.8e-63 214.6 26.1 2.1 1 1 0 1 1 1 1 Permease family NDUF_B12 PF08122.12 KFH40714.1 - 0.51 10.4 2.4 7.7 6.6 0.1 3.4 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family tRNA-synt_1d PF00750.19 KFH40715.1 - 4.2e-60 203.5 0.0 6.6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFH40715.1 - 8e-13 48.6 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DUF4395 PF14340.6 KFH40715.1 - 0.2 12.0 0.7 0.43 10.9 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) PS_pyruv_trans PF04230.13 KFH40716.1 - 2.3e-18 67.1 0.0 1e-17 65.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 KFH40717.1 - 3.7e-12 46.2 8.0 4.4e-12 45.9 8.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH40717.1 - 1.3e-06 28.7 27.1 0.00086 19.5 5.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFH40717.1 - 0.005 16.1 8.2 0.0081 15.4 8.0 1.3 1 1 0 1 1 1 1 UAA transporter family ATP_bind_1 PF03029.17 KFH40718.1 - 2.2e-68 230.6 0.0 4.7e-68 229.6 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PRK PF00485.18 KFH40718.1 - 0.0038 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 KFH40718.1 - 0.0072 15.9 0.0 0.11 12.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.22 KFH40718.1 - 0.0078 15.9 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain MeaB PF03308.16 KFH40718.1 - 0.011 14.7 0.0 0.93 8.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KFH40718.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KFH40718.1 - 0.026 14.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FeoB_N PF02421.18 KFH40718.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.6 KFH40718.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFH40718.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 KFH40718.1 - 0.098 13.0 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH40718.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KFH40718.1 - 0.19 11.3 0.1 1.7 8.2 0.1 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dicty_REP PF05086.12 KFH40719.1 - 0.76 7.7 9.5 0.81 7.6 9.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IMUP PF15761.5 KFH40719.1 - 3.6 8.3 26.5 2.4 8.9 9.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein TPR_19 PF14559.6 KFH40720.1 - 0.039 14.5 3.6 25 5.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH40720.1 - 0.074 13.9 13.8 1.3 10.1 0.4 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFH40720.1 - 0.15 12.5 0.1 17 6.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFH40720.1 - 0.34 10.6 4.2 20 5.0 0.0 4.0 3 0 0 3 3 3 0 TPR repeat Aldo_ket_red PF00248.21 KFH40721.1 - 1.1e-46 159.4 0.0 6.6e-45 153.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GREB1 PF15782.5 KFH40722.1 - 0.16 9.1 4.0 0.18 8.9 4.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KFH40722.1 - 0.45 9.2 7.3 0.61 8.8 7.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 KFH40722.1 - 1 8.9 21.8 1.3 8.5 2.4 2.2 2 0 0 2 2 2 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 KFH40722.1 - 1.3 9.4 16.1 4.1 7.8 6.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nop14 PF04147.12 KFH40722.1 - 5.7 5.0 25.8 0.25 9.5 9.2 2.2 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.6 KFH40722.1 - 6.1 6.5 21.0 0.093 12.4 3.1 3.0 3 0 0 3 3 3 0 FAM176 family FAM110_C PF14160.6 KFH40722.1 - 6.5 7.9 9.5 2.1 9.4 1.6 2.4 2 0 0 2 2 2 0 Centrosome-associated C terminus Menin PF05053.13 KFH40722.1 - 9.6 4.4 18.1 12 4.2 18.1 1.1 1 0 0 1 1 1 0 Menin ChAPs PF09295.10 KFH40724.1 - 2.3e-150 501.0 0.0 3.1e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 KFH40724.1 - 1.9e-05 24.5 0.1 0.0056 16.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH40724.1 - 2e-05 24.6 0.2 0.0037 17.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFH40724.1 - 4.4e-05 23.2 0.3 0.16 12.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH40724.1 - 0.00023 21.0 0.4 0.072 13.2 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH40724.1 - 0.00035 21.2 4.1 0.83 10.6 0.2 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH40724.1 - 0.0029 17.4 0.2 0.99 9.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH40724.1 - 0.018 15.3 1.8 16 5.8 0.0 3.9 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFH40724.1 - 0.032 14.7 0.1 3 8.4 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFH40724.1 - 0.035 14.4 0.4 17 5.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFH40724.1 - 0.036 13.3 5.7 0.058 12.6 2.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH40724.1 - 0.038 14.6 0.5 31 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WSN PF02206.18 KFH40724.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function HIT PF01230.23 KFH40725.1 - 6.9e-19 68.4 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFH40725.1 - 1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFH40725.1 - 0.043 13.7 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KFH40727.1 - 2.4e-09 36.7 1.1 3.2e-09 36.3 1.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KFH40727.1 - 0.0037 17.2 0.2 0.05 13.6 0.1 2.0 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 KFH40727.1 - 0.0066 16.8 1.6 0.36 11.2 0.1 2.1 1 1 1 2 2 2 1 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KFH40727.1 - 0.009 16.1 0.8 0.017 15.2 0.8 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2HC5 PF06221.13 KFH40727.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PhnA_Zn_Ribbon PF08274.12 KFH40727.1 - 0.023 14.6 0.9 0.033 14.1 0.4 1.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon HypA PF01155.19 KFH40727.1 - 0.031 14.3 0.1 0.034 14.2 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KFH40727.1 - 0.05 13.9 1.2 0.11 12.7 1.2 1.6 1 1 1 2 2 2 0 zinc-ribbon DUF2197 PF09963.9 KFH40727.1 - 0.053 13.8 0.1 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) A2L_zn_ribbon PF08792.10 KFH40727.1 - 0.055 13.2 0.3 0.084 12.6 0.3 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-ISL3 PF14690.6 KFH40727.1 - 0.068 13.9 0.8 0.13 13.0 0.1 1.7 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.12 KFH40727.1 - 0.17 11.4 1.8 2.2 7.9 1.9 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Anti-TRAP PF15777.5 KFH40727.1 - 0.53 10.3 3.5 0.3 11.1 1.2 1.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_ribbon_recom PF13408.6 KFH40727.1 - 5.3 7.6 8.7 12 6.5 0.2 2.8 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain A_deaminase PF00962.22 KFH40728.1 - 2.9e-120 401.5 0.1 3.8e-120 401.1 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Prefoldin_2 PF01920.20 KFH40729.1 - 2.2e-12 46.8 2.2 6.3e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit Glyco_transf_41 PF13844.6 KFH40729.1 - 0.1 11.0 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 TMF_TATA_bd PF12325.8 KFH40729.1 - 0.12 12.6 7.7 0.32 11.2 0.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mito_carr PF00153.27 KFH40730.1 - 6.8e-51 170.2 1.2 1.5e-16 60.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_1 PF00018.28 KFH40731.1 - 1.7e-37 126.8 7.3 4.9e-14 51.7 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KFH40731.1 - 6.3e-34 115.6 0.1 1.1e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KFH40731.1 - 5.6e-33 112.6 10.0 2.4e-12 46.5 0.3 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFH40731.1 - 2e-22 78.6 0.2 5.8e-07 29.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 KFH40731.1 - 4.2e-05 23.9 50.3 0.00014 22.2 16.3 6.3 2 1 4 6 6 6 2 Domain of unknown function (DUF1720) SH3_3 PF08239.11 KFH40731.1 - 4.6e-05 23.6 5.1 0.004 17.4 0.8 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 KFH40731.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KFH40731.1 - 0.0016 18.5 0.0 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 SH3 domain UAA PF08449.11 KFH40732.1 - 1.4e-92 310.1 5.4 1.6e-92 309.9 5.4 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFH40732.1 - 0.00074 18.8 6.1 0.0028 16.9 6.1 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFH40732.1 - 0.43 10.8 24.9 0.33 11.1 11.8 3.4 2 2 0 3 3 3 0 EamA-like transporter family TssN PF17555.2 KFH40732.1 - 1.7 8.0 4.9 5.9 6.2 1.6 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF4131 PF13567.6 KFH40732.1 - 6.6 6.4 10.6 8.7 6.0 0.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) TRAM_LAG1_CLN8 PF03798.16 KFH40733.1 - 1.7e-46 158.5 12.8 2.8e-46 157.8 12.8 1.3 1 0 0 1 1 1 1 TLC domain DUF4234 PF14018.6 KFH40733.1 - 0.072 13.2 0.2 0.072 13.2 0.2 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) YqhG PF11079.8 KFH40734.1 - 0.17 10.8 9.1 0.32 9.9 9.1 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Dor1 PF04124.12 KFH40735.1 - 6.6e-51 173.0 0.3 6.7e-42 143.4 0.6 2.2 2 0 0 2 2 2 2 Dor1-like family COG5 PF10392.9 KFH40735.1 - 0.059 13.5 2.8 0.19 11.9 2.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 GP57 PF17594.2 KFH40735.1 - 0.084 12.6 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Voltage_CLC PF00654.20 KFH40736.1 - 1.4e-62 212.0 28.3 1.6e-45 155.9 19.0 2.9 2 1 1 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 KFH40736.1 - 4.9e-05 23.7 0.1 0.026 14.9 0.1 2.5 2 0 0 2 2 2 2 CBS domain LacI PF00356.21 KFH40736.1 - 0.4 10.5 1.2 1 9.2 1.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Arginase PF00491.21 KFH40737.1 - 1.2e-91 307.1 0.0 1.5e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KFH40737.1 - 0.029 14.6 0.6 0.049 13.9 0.5 1.4 1 1 0 1 1 1 0 UPF0489 domain Aconitase PF00330.20 KFH40738.1 - 1.3e-161 538.7 0.0 1.6e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFH40738.1 - 1.7e-43 148.1 0.0 2.7e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KFH40738.1 - 0.2 10.4 0.4 0.59 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF521) E1_dh PF00676.20 KFH40739.1 - 3.7e-112 374.1 0.2 4.5e-112 373.9 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFH40739.1 - 0.00085 18.6 0.2 0.0022 17.2 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Phage_lysozyme PF00959.19 KFH40740.1 - 8.9e-14 51.9 0.0 1.2e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme tRNA-synt_2 PF00152.20 KFH40741.1 - 1.1e-85 287.6 0.0 1.7e-85 286.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFH40741.1 - 1.4e-08 34.6 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KFH40741.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ATP-synt_D PF01813.17 KFH40742.1 - 0.01 15.7 1.0 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 ATP synthase subunit D ZapB PF06005.12 KFH40742.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.8 3 0 0 3 3 3 0 Cell division protein ZapB CAF1A PF12253.8 KFH40742.1 - 0.26 11.5 5.6 0.48 10.6 5.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Eapp_C PF10238.9 KFH40742.1 - 0.93 9.6 3.6 4.8 7.2 0.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein NPR1_interact PF15699.5 KFH40742.1 - 2.6 8.7 10.0 0.6 10.7 4.0 2.5 2 1 0 2 2 2 0 NPR1 interacting Neurochondrin PF05536.11 KFH40743.1 - 2.9e-85 286.9 3.2 3.6e-85 286.6 3.2 1.1 1 0 0 1 1 1 1 Neurochondrin V-ATPase_H_N PF03224.14 KFH40743.1 - 0.00021 20.7 1.0 0.07 12.4 0.5 2.3 2 0 0 2 2 2 2 V-ATPase subunit H Pyr_redox_2 PF07992.14 KFH40744.1 - 2.7e-54 184.4 0.3 3.3e-54 184.1 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFH40744.1 - 1.3e-19 70.5 0.3 7.2e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFH40744.1 - 9e-19 67.8 0.0 2.1e-16 60.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH40744.1 - 5.5e-09 35.7 0.0 8.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH40744.1 - 0.00018 20.8 0.0 0.0011 18.1 0.0 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFH40744.1 - 0.045 13.6 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFH40744.1 - 0.067 13.6 0.1 0.62 10.5 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFH40744.1 - 0.081 12.3 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KFH40744.1 - 0.1 11.3 0.0 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DUF1768 PF08719.11 KFH40745.1 - 1.8e-52 177.8 0.0 2.2e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WD40 PF00400.32 KFH40746.1 - 7.2e-38 127.9 23.7 2.1e-07 31.5 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KFH40746.1 - 1.3e-11 44.2 0.5 2.4e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFH40746.1 - 6.5e-10 39.2 0.7 0.26 11.6 0.0 5.6 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH40746.1 - 8.7e-07 28.0 4.8 0.17 10.5 0.1 5.3 1 1 5 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 KFH40746.1 - 4.2e-05 23.3 1.7 8.4e-05 22.3 1.7 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFH40746.1 - 0.00049 19.5 0.0 0.14 11.4 0.0 2.7 2 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KFH40746.1 - 0.012 15.2 3.7 0.092 12.3 2.0 2.8 1 1 0 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KFH40746.1 - 0.074 12.0 2.2 33 3.2 0.0 3.6 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DNA_ligase_A_M PF01068.21 KFH40747.1 - 8.1e-47 159.5 0.3 1.3e-46 158.8 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFH40747.1 - 2.6e-45 154.9 0.6 4.5e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFH40747.1 - 4.6e-29 100.9 0.0 2e-28 98.9 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 KFH40747.1 - 0.09 12.8 0.1 21 5.2 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain PNKP_ligase PF16542.5 KFH40747.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Ras PF00071.22 KFH40748.1 - 1.4e-52 177.5 0.0 1.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH40748.1 - 5.4e-19 68.6 0.0 7.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH40748.1 - 1.4e-06 27.9 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RCC1_2 PF13540.6 KFH40749.1 - 9.1e-13 47.6 7.3 2.5e-07 30.3 0.1 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KFH40749.1 - 8.3e-12 45.5 1.5 1.9e-05 25.2 0.8 5.0 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S5 PF00333.20 KFH40749.1 - 0.047 13.7 0.6 0.095 12.7 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Kelch_6 PF13964.6 KFH40749.1 - 0.079 13.3 0.3 3 8.3 0.1 3.2 3 1 1 4 4 4 0 Kelch motif CC2-LZ PF16516.5 KFH40750.1 - 0.62 10.5 5.3 0.35 11.3 0.4 2.7 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RINGv PF12906.7 KFH40751.1 - 1.9e-09 37.5 3.9 1.2e-08 35.0 1.1 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KFH40751.1 - 0.042 14.2 3.5 0.17 12.3 1.1 2.2 2 0 0 2 2 2 0 Ring finger domain zf-MIZ PF02891.20 KFH40751.1 - 0.047 13.4 1.9 0.078 12.7 1.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD_4 PF16866.5 KFH40751.1 - 0.088 12.9 6.5 1.1 9.5 2.7 2.3 1 1 1 2 2 2 0 PHD-finger PHD PF00628.29 KFH40751.1 - 0.77 9.7 6.4 0.13 12.2 2.1 1.8 2 0 0 2 2 2 0 PHD-finger DUF202 PF02656.15 KFH40751.1 - 4.3 7.8 8.2 25 5.4 7.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) BING4CT PF08149.11 KFH40752.1 - 1.4e-41 140.1 0.0 5e-36 122.4 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KFH40752.1 - 1.1e-07 32.1 1.4 5.9 7.3 0.0 6.9 4 1 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFH40752.1 - 4.1e-05 24.3 0.0 0.26 12.2 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KFH40752.1 - 0.00061 19.0 0.0 0.0032 16.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 KFH40752.1 - 0.079 11.5 0.0 2.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain AAA_18 PF13238.6 KFH40753.1 - 0.00013 22.5 0.0 0.00057 20.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 KFH40753.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 KFH40753.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KFH40753.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KFH40753.1 - 0.034 14.4 0.0 0.07 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFH40753.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CoaE PF01121.20 KFH40753.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_22 PF13401.6 KFH40753.1 - 0.15 12.3 0.0 0.55 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH40753.1 - 0.19 12.2 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Pyridoxal_deC PF00282.19 KFH40754.1 - 2.2e-17 62.8 0.0 3.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFH40754.1 - 1.4e-06 27.5 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFH40754.1 - 0.00087 18.7 0.1 0.0013 18.1 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SOAR PF16533.5 KFH40755.1 - 0.1 12.5 4.4 0.36 10.8 4.4 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region Aa_trans PF01490.18 KFH40756.1 - 1.8e-65 221.3 25.8 2.1e-65 221.0 25.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFH40756.1 - 5.6e-05 22.4 10.2 0.00014 21.0 10.2 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family SnAC PF14619.6 KFH40756.1 - 0.16 12.6 0.2 0.27 11.8 0.2 1.3 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex RIBIOP_C PF04950.12 KFH40757.1 - 4.3e-109 364.5 0.0 7.2e-109 363.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFH40757.1 - 3.1e-17 62.4 0.0 6.6e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Proteasome PF00227.26 KFH40758.1 - 2.3e-56 190.3 0.1 3e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFH40758.1 - 1.2e-10 40.8 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature BCDHK_Adom3 PF10436.9 KFH40759.1 - 3.3e-76 254.6 0.0 4.8e-76 254.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFH40759.1 - 2.1e-12 47.5 0.0 4.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFH40759.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stc1 PF12898.7 KFH40760.1 - 2.2e-05 24.9 0.4 3.3e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Stc1 domain zf-HC3 PF16827.5 KFH40760.1 - 0.03 14.5 1.3 0.073 13.3 1.3 1.7 1 0 0 1 1 1 0 zinc-finger MRI PF15325.6 KFH40760.1 - 0.35 12.0 5.9 3.1 8.9 2.3 2.4 1 1 1 2 2 2 0 Modulator of retrovirus infection PTH2 PF01981.16 KFH40761.1 - 3.2e-47 159.6 0.1 4.2e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonuclease_3 PF00636.26 KFH40762.1 - 8.5e-42 142.1 0.0 4e-21 75.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFH40762.1 - 3.5e-24 85.4 0.0 3.5e-11 43.4 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KFH40762.1 - 9.4e-23 80.2 0.0 3.5e-22 78.4 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KFH40762.1 - 2e-16 60.3 0.1 3.8e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH40762.1 - 3.5e-16 59.5 0.0 7.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFH40762.1 - 1.1e-10 41.8 0.0 2.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_34 PF05637.12 KFH40764.1 - 4.1e-69 232.9 0.0 5.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ras PF00071.22 KFH40765.1 - 5e-56 188.8 0.0 5.7e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH40765.1 - 7.5e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH40765.1 - 2.9e-07 30.1 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFH40765.1 - 0.0028 17.1 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFH40765.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 KFH40766.1 - 1.4e-33 116.0 0.0 1.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFH40766.1 - 0.00012 21.2 1.1 0.0021 17.1 1.1 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KFH40766.1 - 0.0028 18.2 0.0 0.0038 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFH40766.1 - 0.013 15.6 0.0 0.06 13.4 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFH40766.1 - 0.084 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KFH40766.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KFH40766.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DSPc PF00782.20 KFH40767.1 - 5.3e-12 45.7 0.0 2.6e-06 27.3 0.0 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFH40767.1 - 0.00051 20.3 0.0 0.00098 19.4 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain Rtt106 PF08512.12 KFH40768.1 - 3.1e-27 94.8 0.0 1.3e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KFH40768.1 - 0.00019 21.5 0.0 0.00052 20.0 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Flocculin PF00624.18 KFH40768.1 - 0.095 13.0 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Flocculin repeat NOA36 PF06524.12 KFH40768.1 - 0.76 9.0 29.0 1.1 8.5 29.0 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KFH40768.1 - 4.4 6.6 29.2 6.3 6.1 29.2 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 KFH40768.1 - 8.7 6.6 9.8 14 5.9 9.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-CHCC PF10276.9 KFH40769.1 - 0.0026 17.8 2.9 1 9.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2 PF00096.26 KFH40769.1 - 0.0098 16.3 1.0 0.0098 16.3 1.0 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH40769.1 - 0.022 15.2 1.2 0.022 15.2 1.2 3.9 3 1 1 4 4 4 0 Zinc-finger double domain Zn_ribbon_recom PF13408.6 KFH40769.1 - 0.24 11.9 4.8 2.9 8.5 0.9 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain PyrI_C PF02748.15 KFH40769.1 - 0.25 11.3 6.3 15 5.5 5.2 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Actin_micro PF17003.5 KFH40769.1 - 1.2 8.2 2.8 3.6 6.7 2.8 1.6 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_4 PF13894.6 KFH40769.1 - 3.6 8.7 26.5 0.16 12.9 1.3 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Snf7 PF03357.21 KFH40771.1 - 6.4e-41 139.8 9.0 7.6e-41 139.6 9.0 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KFH40771.1 - 0.0001 22.7 5.5 0.015 15.8 1.6 2.9 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein Zwint PF15556.6 KFH40771.1 - 0.0071 15.9 9.2 0.0092 15.5 9.2 1.3 1 0 0 1 1 1 1 ZW10 interactor CENP-F_leu_zip PF10473.9 KFH40771.1 - 0.012 15.7 14.9 0.15 12.1 14.1 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lyase_aromatic PF00221.19 KFH40771.1 - 0.038 12.6 0.1 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase CLZ PF16526.5 KFH40771.1 - 0.097 13.0 11.9 1.2 9.5 0.0 3.8 3 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HsbA PF12296.8 KFH40771.1 - 0.1 13.0 2.3 0.82 10.1 2.3 2.2 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Peptidase_S46 PF10459.9 KFH40771.1 - 0.12 11.0 6.0 0.15 10.7 6.0 1.0 1 0 0 1 1 1 0 Peptidase S46 Alpha-2-MRAP_C PF06401.11 KFH40771.1 - 0.17 11.8 8.6 1.2 9.0 7.9 2.1 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Muted PF14942.6 KFH40771.1 - 0.18 12.1 11.1 0.29 11.5 4.0 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Glutaredoxin PF00462.24 KFH40771.1 - 0.23 11.7 1.2 4.6 7.5 0.2 2.7 2 1 1 3 3 3 0 Glutaredoxin Sec34 PF04136.15 KFH40771.1 - 0.25 11.2 4.1 0.32 10.9 1.0 2.1 1 1 0 2 2 2 0 Sec34-like family Mod_r PF07200.13 KFH40771.1 - 0.32 11.1 13.1 0.21 11.7 8.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 KFH40771.1 - 0.32 11.6 8.5 3.2 8.4 0.0 3.5 1 1 2 3 3 3 0 SlyX DUF848 PF05852.11 KFH40771.1 - 0.41 10.8 9.4 0.56 10.3 7.4 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2205 PF10224.9 KFH40771.1 - 0.43 10.6 9.0 0.37 10.8 4.9 2.8 1 1 1 3 3 3 0 Short coiled-coil protein DASH_Dam1 PF08653.10 KFH40771.1 - 0.46 10.3 3.6 15 5.5 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 NYD-SP28_assoc PF14775.6 KFH40771.1 - 0.49 10.5 6.4 4.8 7.4 0.7 3.0 2 1 1 3 3 3 0 Sperm tail C-terminal domain Prominin PF05478.11 KFH40771.1 - 0.6 8.0 4.0 0.75 7.7 4.0 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 KFH40771.1 - 0.66 10.6 9.9 5.2 7.8 5.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KFH40771.1 - 0.77 10.2 11.8 10 6.6 0.0 3.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KFH40771.1 - 1.6 7.2 10.9 14 4.2 10.9 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 KFH40771.1 - 2 8.4 9.2 7.7 6.5 6.7 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 KFH40771.1 - 2 7.7 8.4 2.9 7.1 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4446 PF14584.6 KFH40771.1 - 2.4 8.2 10.2 5.7 6.9 3.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) APG6_N PF17675.1 KFH40771.1 - 2.6 8.6 19.6 6.2 7.4 7.3 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 KFH40771.1 - 4.9 7.4 0.0 4.9 7.4 0.0 3.9 2 1 2 4 4 4 0 Haemolysin XhlA Uso1_p115_C PF04871.13 KFH40771.1 - 8.5 6.8 19.6 2e+02 2.4 19.6 2.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Vfa1 PF08432.10 KFH40775.1 - 1.1e-54 185.5 20.4 1.3e-54 185.3 20.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 KFH40775.1 - 0.27 10.2 3.5 0.27 10.2 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.11 KFH40775.1 - 2 6.8 14.7 2.3 6.6 14.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SET PF00856.28 KFH40775.1 - 2.7 8.4 6.6 4.4 7.7 6.6 1.5 1 1 0 1 1 1 0 SET domain SAPS PF04499.15 KFH40775.1 - 3.2 6.4 8.3 3.6 6.3 8.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 KFH40775.1 - 3.9 5.5 13.6 4.3 5.3 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFH40775.1 - 4.7 5.4 17.1 5.9 5.0 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 KFH40775.1 - 5.2 7.1 11.8 0.53 10.3 6.4 1.8 1 1 1 2 2 2 0 Telomere-associated protein TERB2 ANAPC_CDC26 PF10471.9 KFH40775.1 - 7.2 7.5 16.1 2 9.3 6.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TFB6 PF17110.5 KFH40775.1 - 7.8 6.2 8.0 14 5.4 8.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TPR_12 PF13424.6 KFH40776.1 - 3.3e-15 56.1 8.8 3.1e-05 24.2 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH40776.1 - 1.1e-07 32.3 3.4 0.3 11.8 0.1 4.5 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH40776.1 - 1.7e-06 27.7 10.1 0.026 14.6 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFH40776.1 - 0.00012 21.9 1.2 1.1 9.4 0.0 3.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH40776.1 - 0.00016 22.1 1.4 0.0036 17.8 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH40776.1 - 0.00023 20.9 3.3 0.05 13.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH40776.1 - 0.0004 20.4 0.4 2.8 8.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_2 PF12796.7 KFH40776.1 - 0.00076 20.0 0.1 0.0057 17.2 0.0 2.3 2 1 1 3 3 2 1 Ankyrin repeats (3 copies) TPR_14 PF13428.6 KFH40776.1 - 0.001 19.7 7.8 7.8 7.6 0.3 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat Ank_4 PF13637.6 KFH40776.1 - 0.0032 18.0 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_10 PF13374.6 KFH40776.1 - 0.0074 16.1 10.3 0.65 9.9 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Aminotran_3 PF00202.21 KFH40776.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III TPR_17 PF13431.6 KFH40776.1 - 0.031 14.6 0.2 0.49 10.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH40776.1 - 0.034 13.5 3.9 3.3 7.0 0.6 2.9 3 1 0 3 3 3 0 MalT-like TPR region HET PF06985.11 KFH40776.1 - 0.066 13.6 0.1 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) TPR_4 PF07721.14 KFH40776.1 - 3.7 8.5 10.2 3.4 8.6 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat WD40 PF00400.32 KFH40777.1 - 4.7e-23 81.1 14.0 0.0005 20.8 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KFH40777.1 - 7.1e-13 48.2 4.4 1.8e-12 46.9 4.4 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFH40777.1 - 4.5e-06 26.9 0.3 0.46 10.8 0.0 3.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFH40777.1 - 6.8e-05 22.6 2.5 6.8e-05 22.6 2.5 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KFH40777.1 - 0.0014 17.4 0.1 0.6 8.7 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 KFH40777.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box SmpA_OmlA PF04355.13 KFH40777.1 - 0.12 12.2 0.2 2.9 7.8 0.1 2.6 2 0 0 2 2 2 0 SmpA / OmlA family MgtE_N PF03448.17 KFH40777.1 - 0.18 12.4 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain PH_10 PF15411.6 KFH40778.1 - 1.7e-37 128.4 0.0 3.9e-37 127.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFH40778.1 - 1.2e-28 100.6 0.1 2.1e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 KFH40778.1 - 1.7e-28 98.7 0.1 3.5e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 KFH40778.1 - 6.5e-08 32.4 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 KFH40778.1 - 0.037 14.5 0.2 0.097 13.2 0.2 1.7 1 1 0 1 1 1 0 PH domain PRIMA1 PF16101.5 KFH40778.1 - 0.6 10.2 4.0 2.7 8.0 4.0 2.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_18 PF00704.28 KFH40781.1 - 9.7e-53 179.9 1.7 1.4e-52 179.3 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFH40781.1 - 3.5e-10 39.8 0.1 0.0015 18.5 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KFH40781.1 - 1.9e-07 31.4 6.7 1.9e-07 31.4 6.7 4.5 4 0 0 4 4 4 1 Chitin recognition protein Aspzincin_M35 PF14521.6 KFH40781.1 - 0.1 13.1 0.6 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Glyco_transf_28 PF03033.20 KFH40782.1 - 1.4e-17 64.1 0.0 2.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFH40782.1 - 0.00096 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFH40782.1 - 0.0082 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NYN PF01936.18 KFH40784.1 - 3e-06 27.8 0.0 2.8e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 NYN domain Fungal_trans_2 PF11951.8 KFH40785.1 - 3.2e-05 22.9 0.1 4.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH40785.1 - 0.0012 18.9 3.1 0.0032 17.6 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0175 PF03683.13 KFH40786.1 - 0.0018 17.9 0.2 0.0052 16.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0175) DUF2993 PF11209.8 KFH40786.1 - 0.011 16.0 0.2 0.35 11.1 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2993) RhoGAP PF00620.27 KFH40787.1 - 6.3e-46 156.0 0.0 6.3e-46 156.0 0.0 2.6 3 1 1 4 4 4 1 RhoGAP domain LIM PF00412.22 KFH40787.1 - 1.3e-13 51.0 16.1 2.6e-09 37.1 1.6 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.12 KFH40787.1 - 0.13 11.9 7.4 5.5 6.7 0.6 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain KASH_CCD PF14662.6 KFH40787.1 - 2.1 8.1 21.4 15 5.4 21.3 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KFH40787.1 - 2.9 8.3 15.8 8.7 6.7 15.8 1.8 1 0 0 1 1 1 0 Fez1 DUF848 PF05852.11 KFH40787.1 - 3.8 7.6 11.2 0.35 11.0 3.5 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PRKG1_interact PF15898.5 KFH40787.1 - 5.9 7.8 14.8 3.6 8.6 0.7 3.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain IFT20 PF14931.6 KFH40787.1 - 6.2 7.0 12.0 0.85 9.8 3.6 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Zn-ribbon_8 PF09723.10 KFH40787.1 - 6.2 7.0 17.7 2.9 8.1 0.6 4.2 3 1 2 5 5 5 0 Zinc ribbon domain zf-FLZ PF04570.14 KFH40787.1 - 7.8 6.1 11.9 1.7 8.2 7.1 2.4 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 zf-ribbon_3 PF13248.6 KFH40787.1 - 8.6 5.9 17.2 0.76 9.3 0.0 4.1 5 1 0 5 5 5 0 zinc-ribbon domain PPR PF01535.20 KFH40788.1 - 4.1e-16 58.0 15.0 0.005 17.0 0.3 8.8 9 0 0 9 9 9 4 PPR repeat PPR_2 PF13041.6 KFH40788.1 - 1.4e-15 57.2 10.6 2.7e-05 24.3 0.1 7.1 4 2 3 7 7 7 3 PPR repeat family PPR_3 PF13812.6 KFH40788.1 - 2.8e-08 33.7 0.1 0.066 13.3 0.0 5.3 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFH40788.1 - 1.9e-07 30.7 3.4 3.8 7.3 0.0 6.1 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 KFH40788.1 - 0.00011 21.7 0.1 0.028 13.8 0.0 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF4071 PF13281.6 KFH40788.1 - 0.0063 15.6 0.0 0.77 8.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Cytomega_gL PF01801.16 KFH40788.1 - 0.0089 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L SPOB_a PF14689.6 KFH40788.1 - 0.018 14.7 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_19 PF14559.6 KFH40788.1 - 0.033 14.7 0.0 3.5 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PBP_sp32 PF07222.12 KFH40788.1 - 4.5 6.7 14.9 7.6 5.9 14.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PI3_PI4_kinase PF00454.27 KFH40789.1 - 1.4e-44 152.8 0.0 2.2e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CLASP_N PF12348.8 KFH40790.1 - 1.8e-127 423.5 0.3 1.1e-84 283.5 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 KFH40790.1 - 2.5e-06 27.3 1.4 1.5 9.3 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFH40790.1 - 0.00093 19.5 8.2 1.7 9.1 0.2 4.9 4 1 1 5 5 5 2 HEAT repeats MMS19_C PF12460.8 KFH40790.1 - 0.0021 17.3 3.0 0.011 14.9 0.5 2.4 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KFH40790.1 - 0.0023 18.0 0.1 2.8 7.9 0.0 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFH40790.1 - 0.016 13.8 1.3 0.18 10.3 0.0 3.2 5 0 0 5 5 5 0 Adaptin N terminal region RVT_thumb PF06817.14 KFH40790.1 - 0.018 14.9 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF3361 PF11841.8 KFH40790.1 - 0.15 12.0 0.1 9.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) rRNA_processing PF08524.11 KFH40792.1 - 1.6e-05 25.0 29.3 0.0036 17.3 6.4 2.1 1 1 1 2 2 2 2 rRNA processing DUF4210 PF13915.6 KFH40793.1 - 1.2e-33 115.5 0.2 2.6e-33 114.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KFH40793.1 - 1.3e-20 73.3 0.2 2.8e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis FRG2 PF15315.6 KFH40794.1 - 8.3 6.6 17.6 11 6.2 17.6 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 BSP PF04450.12 KFH40795.1 - 1.7e-77 259.9 0.0 2.1e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KFH40795.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF3632 PF12311.8 KFH40797.1 - 1.9e-26 93.6 0.2 2.9e-26 93.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) 2-oxoacid_dh PF00198.23 KFH40798.1 - 1.2e-75 254.0 0.1 1.5e-75 253.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFH40798.1 - 1.2e-19 69.9 1.0 2.8e-19 68.7 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFH40798.1 - 1.3e-13 51.0 0.4 5e-13 49.2 0.4 2.1 1 0 0 1 1 1 1 e3 binding domain Calycin_like PF13944.6 KFH40798.1 - 0.019 15.2 1.0 0.35 11.2 0.1 2.7 1 1 1 2 2 2 0 Calycin-like beta-barrel domain Nucleoporin_FG PF13634.6 KFH40799.1 - 3.5e-07 31.0 107.1 2.9e-06 28.0 57.3 5.4 2 1 2 4 4 4 3 Nucleoporin FG repeat region FAM199X PF15814.5 KFH40799.1 - 0.084 11.9 0.0 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein family FAM199X Vps53_N PF04100.12 KFH40799.1 - 0.22 10.5 1.2 0.32 9.9 1.2 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal FliJ PF02050.16 KFH40799.1 - 0.39 10.9 3.4 12 6.2 0.2 3.7 4 0 0 4 4 4 0 Flagellar FliJ protein Methyltransf_25 PF13649.6 KFH40800.1 - 5.7e-10 39.8 0.0 1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40800.1 - 7.2e-09 36.2 0.0 1.4e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40800.1 - 5.2e-07 30.3 0.0 1.2e-06 29.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40800.1 - 1.4e-06 28.2 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40800.1 - 5.1e-05 23.1 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH40800.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MTS PF05175.14 KFH40800.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Pam17 PF08566.10 KFH40801.1 - 4.5 7.1 4.8 1.1 9.1 0.8 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Fip1 PF05182.13 KFH40802.1 - 2.2e-20 71.9 0.9 4.2e-20 71.0 0.9 1.5 1 0 0 1 1 1 1 Fip1 motif Ndc1_Nup PF09531.10 KFH40802.1 - 0.53 8.9 2.3 0.55 8.8 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_3_Rpc31 PF11705.8 KFH40804.1 - 1.7e-58 198.5 0.6 2.2e-58 198.2 0.6 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FoP_duplication PF13865.6 KFH40804.1 - 8.6 7.0 13.2 1.9 9.1 3.6 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Sec7 PF01369.20 KFH40805.1 - 2.9e-70 235.7 2.8 4.2e-70 235.1 0.7 2.4 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KFH40805.1 - 1.3e-39 135.6 2.4 1.3e-39 135.6 2.4 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFH40805.1 - 7.9e-34 115.4 11.1 2.2e-32 110.7 0.0 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 KFH40805.1 - 1.2e-22 80.4 4.8 1.6e-20 73.5 0.3 3.5 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF2456 PF10445.9 KFH40806.1 - 2.6e-19 69.1 0.4 4.9e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) AtuA PF07287.11 KFH40808.1 - 2.1e-127 424.7 0.3 2.5e-127 424.4 0.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_4 PF01565.23 KFH40809.1 - 3.5e-17 62.4 1.0 5.8e-17 61.7 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KFH40809.1 - 3.6e-12 46.7 0.7 1.5e-11 44.6 0.7 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD-oxidase_C PF02913.19 KFH40809.1 - 0.11 12.1 0.0 9.2 5.8 0.0 2.4 3 0 0 3 3 3 0 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.18 KFH40810.1 - 1.5e-12 47.1 0.9 4.4e-12 45.6 0.4 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH40810.1 - 0.00012 22.1 13.7 0.00024 21.2 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3613 PF12266.8 KFH40810.1 - 0.1 12.4 0.3 2.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) RAP1 PF07218.11 KFH40810.1 - 5.4 5.2 6.7 8.1 4.6 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Frag1 PF10277.9 KFH40811.1 - 1.5e-15 57.4 9.3 1.9e-15 57.0 9.3 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFH40811.1 - 0.00035 20.2 9.8 0.0009 18.9 9.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Glyco_hydro_61 PF03443.14 KFH40812.1 - 3.4e-66 223.1 0.0 4.8e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sulfate_transp PF00916.20 KFH40813.1 - 3.1e-107 358.6 18.5 4.2e-107 358.2 18.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFH40813.1 - 3.7e-07 29.8 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFH40813.1 - 0.00059 20.2 4.2 0.00059 20.2 4.2 3.2 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily Chromo PF00385.24 KFH40815.1 - 8.4e-13 48.0 1.8 3.9e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain GEN1_C PF18380.1 KFH40815.1 - 1.7 9.6 0.1 1.7 9.6 0.1 3.1 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Plus-3 PF03126.18 KFH40816.1 - 1e-24 87.1 0.0 2.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain Brix PF04427.18 KFH40817.1 - 6.7e-31 107.9 0.0 8.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 KFH40818.1 - 3e-23 82.5 10.0 4.3e-23 82.0 10.0 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFH40818.1 - 1.4e-12 47.3 0.9 3e-12 46.3 0.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFH40818.1 - 0.00057 20.2 7.9 0.00057 20.2 7.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF4094 PF13334.6 KFH40818.1 - 0.19 12.1 7.3 1.1 9.7 0.1 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.11 KFH40818.1 - 0.19 11.2 6.3 0.19 11.2 1.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TMCO5 PF14992.6 KFH40818.1 - 0.29 10.7 6.7 1.3 8.5 6.7 2.1 1 1 0 1 1 1 0 TMCO5 family MCU PF04678.13 KFH40818.1 - 0.38 10.8 5.4 2 8.5 5.4 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter ING PF12998.7 KFH40818.1 - 1.4 9.5 6.9 2.7 8.6 0.9 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.10 KFH40818.1 - 1.7 8.8 11.2 3.1 8.0 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family F-box-like PF12937.7 KFH40819.1 - 3.3e-08 33.3 2.7 9.2e-08 31.9 2.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH40819.1 - 7.6e-08 32.0 1.2 7.6e-08 32.0 1.2 1.9 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.6 KFH40819.1 - 0.0049 17.6 4.5 0.032 15.0 2.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFH40819.1 - 0.015 15.3 4.8 0.6 10.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFH40819.1 - 0.032 14.1 1.9 0.56 10.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FAM221 PF14753.6 KFH40819.1 - 0.12 11.9 4.8 0.21 11.1 4.8 1.3 1 0 0 1 1 1 0 Protein FAM221A/B LRR_4 PF12799.7 KFH40819.1 - 0.61 10.6 8.9 36 5.0 0.0 5.6 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) ERG4_ERG24 PF01222.17 KFH40820.1 - 8.4e-138 459.7 19.6 9.8e-138 459.5 19.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Pox_Ag35 PF03286.14 KFH40820.1 - 0.38 10.5 2.7 0.53 10.0 2.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SET PF00856.28 KFH40821.1 - 0.0037 17.7 0.0 0.0077 16.6 0.0 1.7 1 1 0 1 1 1 1 SET domain LRR_12 PF18837.1 KFH40821.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat GDPD PF03009.17 KFH40823.1 - 2e-30 106.4 0.0 1e-29 104.0 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4207 PF13904.6 KFH40823.1 - 0.04 13.6 0.7 0.06 13.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) COQ7 PF03232.13 KFH40824.1 - 5.6e-71 237.8 0.7 6.8e-71 237.6 0.7 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KFH40824.1 - 0.0015 18.9 0.1 0.0038 17.6 0.0 1.7 2 0 0 2 2 2 1 Rubrerythrin Glyco_hydro_47 PF01532.20 KFH40825.1 - 1.5e-169 564.7 0.1 1.8e-169 564.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UPF1_Zn_bind PF09416.10 KFH40826.1 - 1.8e-68 229.3 3.8 1.8e-68 229.3 3.8 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KFH40826.1 - 4.7e-61 205.9 0.0 1.3e-60 204.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFH40826.1 - 1e-54 186.1 3.1 3e-30 105.9 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFH40826.1 - 9.5e-33 112.3 0.0 2.1e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFH40826.1 - 3.3e-13 49.8 0.3 1.1e-11 44.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH40826.1 - 7.2e-10 39.4 0.1 3.8e-09 37.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFH40826.1 - 4e-05 23.7 0.0 8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFH40826.1 - 0.00019 21.3 0.0 0.75 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFH40826.1 - 0.0005 19.4 0.6 0.0085 15.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFH40826.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KFH40826.1 - 0.0012 18.1 0.2 0.2 10.8 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase DEAD PF00270.29 KFH40826.1 - 0.0017 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 KFH40826.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain UvrD-helicase PF00580.21 KFH40826.1 - 0.0046 16.5 0.0 0.022 14.3 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KFH40826.1 - 0.03 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 KaiC SRP54 PF00448.22 KFH40826.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_2 PF07719.17 KFH40827.1 - 1.6e-44 146.5 14.8 7.5e-05 22.6 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 KFH40827.1 - 2.1e-43 144.4 16.2 8.3e-06 25.4 0.0 11.3 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 KFH40827.1 - 1.6e-28 97.0 2.2 1.4e-06 28.3 0.0 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFH40827.1 - 2.9e-25 88.6 4.2 1.9e-05 25.2 0.4 6.2 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFH40827.1 - 9.8e-25 84.7 16.7 0.00048 20.1 0.0 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFH40827.1 - 1.2e-19 70.3 18.7 0.00019 21.7 0.1 8.4 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFH40827.1 - 6.8e-18 64.1 16.1 5.1e-05 22.9 0.0 8.8 7 1 2 9 9 9 4 TPR repeat TPR_19 PF14559.6 KFH40827.1 - 9.6e-17 61.3 14.9 0.00049 20.6 0.7 6.6 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFH40827.1 - 1.1e-15 57.5 3.2 9e-06 25.8 0.1 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFH40827.1 - 5.1e-15 54.9 10.6 0.013 16.3 0.5 9.4 4 2 6 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH40827.1 - 3.6e-11 42.3 10.0 0.21 11.7 0.0 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFH40827.1 - 3.2e-07 30.0 15.8 0.46 10.4 0.2 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH40827.1 - 2.4e-06 27.2 0.9 3.1e-05 23.5 0.8 2.5 1 1 1 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 KFH40827.1 - 0.00013 21.3 2.7 0.9 9.0 0.0 4.6 4 0 0 4 4 4 2 SHNi-TPR TPR_6 PF13174.6 KFH40827.1 - 0.00014 22.3 21.8 0.2 12.3 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH40827.1 - 0.00016 21.8 11.2 0.23 11.7 0.3 5.4 2 2 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KFH40827.1 - 0.0035 17.4 1.7 18 5.4 0.0 5.0 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 KFH40827.1 - 0.027 14.6 12.1 0.067 13.3 1.1 4.3 4 1 1 5 5 5 0 MAS20 protein import receptor TPR_4 PF07721.14 KFH40827.1 - 0.052 14.2 2.4 21 6.1 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KFH40827.1 - 0.097 12.8 13.6 28 4.9 0.0 6.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 KFH40827.1 - 0.75 8.6 25.9 0.15 10.9 0.3 4.3 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 Sel1 PF08238.12 KFH40827.1 - 1.6 9.5 5.6 8.2 7.3 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat TPR_20 PF14561.6 KFH40827.1 - 1.7 9.0 9.7 25 5.3 0.3 4.4 5 1 0 5 5 3 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 KFH40828.1 - 3.3e-25 89.3 0.0 6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV MMR_HSR1_C PF08438.10 KFH40829.1 - 4e-37 127.2 0.0 8e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KFH40829.1 - 7.6e-17 61.4 0.0 2.2e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFH40829.1 - 3.8e-06 26.5 0.1 0.00012 21.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFH40829.1 - 0.0016 18.1 0.2 1 8.9 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFH40829.1 - 0.0091 16.1 0.4 0.25 11.4 0.2 2.8 3 0 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KFH40829.1 - 0.057 13.3 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFH40829.1 - 0.08 13.5 0.0 0.46 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KFH40829.1 - 0.084 12.6 0.2 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 KFH40829.1 - 0.098 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KFH40829.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PLDc PF00614.22 KFH40830.1 - 5.9e-18 64.2 0.4 4.2e-08 33.0 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFH40830.1 - 2.9e-12 46.6 0.0 1.4e-06 28.3 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KFH40830.1 - 1.1e-06 28.5 0.0 4.6e-06 26.6 0.0 2.1 2 1 0 2 2 2 1 PX domain Fungal_trans PF04082.18 KFH40831.1 - 9.6e-31 106.8 0.2 1.6e-30 106.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH40831.1 - 5.6e-10 39.2 11.0 1.2e-09 38.1 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KFH40831.1 - 0.093 12.8 0.4 0.25 11.5 0.4 1.8 1 0 0 1 1 1 0 bZIP transcription factor CCDC-167 PF15188.6 KFH40831.1 - 0.12 12.7 0.3 0.37 11.1 0.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TIR_3 PF18567.1 KFH40831.1 - 0.18 11.8 0.9 0.37 10.8 0.9 1.5 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain Utp21 PF04192.12 KFH40832.1 - 2.1e-82 276.1 0.0 3.2e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFH40832.1 - 1.4e-17 63.7 16.7 1.1e-06 29.2 0.3 8.6 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40832.1 - 2e-12 47.3 0.0 0.017 15.4 0.0 6.2 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH40832.1 - 1.4e-06 27.2 0.1 0.73 8.4 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFH40832.1 - 5.2e-06 25.2 0.0 1.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KFH40832.1 - 0.029 13.1 0.0 5.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like GTP1_OBG PF01018.22 KFH40833.1 - 4.2e-42 143.4 1.8 6.8e-41 139.4 1.8 2.1 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFH40833.1 - 6.7e-23 81.0 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFH40833.1 - 2.4e-06 27.2 0.1 6e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KFH40833.1 - 0.00014 20.9 0.0 0.29 10.1 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KFH40833.1 - 0.028 13.9 0.0 0.4 10.1 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 KFH40833.1 - 0.032 14.7 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF5591 PF17884.1 KFH40833.1 - 0.038 13.9 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Ploopntkinase3 PF18751.1 KFH40833.1 - 0.05 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 GTP_EFTU PF00009.27 KFH40833.1 - 0.079 12.5 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TFCD_C PF12612.8 KFH40835.1 - 4.8e-30 104.8 0.1 1.4e-29 103.3 0.1 1.9 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KFH40835.1 - 0.00016 22.0 2.0 0.059 13.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats IFRD PF05004.13 KFH40835.1 - 0.009 15.2 0.1 0.028 13.5 0.1 1.8 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KFH40835.1 - 0.0095 16.1 5.8 0.5 10.8 0.0 5.7 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KFH40835.1 - 0.012 16.2 0.2 1.5 9.4 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region EzrA PF06160.12 KFH40836.1 - 0.00013 20.3 13.4 0.00013 20.3 13.4 3.0 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KFH40836.1 - 0.00047 20.3 6.0 0.00047 20.3 6.0 5.6 4 1 2 6 6 6 2 ABC transporter C-terminal domain DUF4226 PF10774.9 KFH40836.1 - 0.004 17.4 4.7 0.004 17.4 4.7 3.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4226) APG6_N PF17675.1 KFH40836.1 - 0.0062 17.1 19.9 0.0062 17.1 19.9 4.5 2 1 1 4 4 4 1 Apg6 coiled-coil region CorA PF01544.18 KFH40836.1 - 1.1 8.5 10.9 0.22 10.8 7.1 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4239 PF14023.6 KFH40836.1 - 3.5 7.3 7.6 0.5 10.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Prothymosin PF03247.14 KFH40837.1 - 0.01 16.3 22.0 0.016 15.7 22.0 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2052 PF09747.9 KFH40837.1 - 0.023 14.8 11.9 0.026 14.7 11.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 KFH40837.1 - 0.04 13.6 4.3 0.055 13.1 4.3 1.5 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 KFH40837.1 - 0.054 11.6 0.7 0.066 11.3 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KFH40837.1 - 0.055 11.6 7.8 0.051 11.7 7.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ferlin_C PF16165.5 KFH40837.1 - 0.064 13.2 2.4 0.084 12.8 2.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Nop14 PF04147.12 KFH40837.1 - 0.075 11.2 7.6 0.061 11.5 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family SLAIN PF15301.6 KFH40837.1 - 0.099 11.9 7.1 0.12 11.6 7.1 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family TRAP_alpha PF03896.16 KFH40837.1 - 0.83 8.8 4.7 0.97 8.6 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 KFH40837.1 - 0.85 9.4 7.4 1.4 8.7 7.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PAC1 PF16094.5 KFH40837.1 - 2.4 7.3 5.0 2.6 7.1 5.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CENP-B_dimeris PF09026.10 KFH40837.1 - 3.1 8.3 12.7 5.5 7.4 12.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KFH40837.1 - 3.6 6.8 11.6 5.2 6.3 11.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 KFH40837.1 - 3.8 6.8 13.1 5.1 6.4 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 KFH40837.1 - 3.9 6.4 14.3 5.2 6.0 14.3 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KFH40837.1 - 4.9 5.3 11.0 4.6 5.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein MscS_TM PF12794.7 KFH40837.1 - 6.4 5.5 4.5 8.1 5.2 4.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HSP90 PF00183.18 KFH40837.1 - 7.4 5.3 8.4 9 5.1 8.4 1.1 1 0 0 1 1 1 0 Hsp90 protein Methyltr_RsmB-F PF01189.17 KFH40838.1 - 1.1e-33 116.6 0.0 6.6e-26 91.2 0.0 3.1 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Mitofilin PF09731.9 KFH40838.1 - 1.9 7.3 10.6 0.013 14.4 2.2 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein His_Phos_2 PF00328.22 KFH40839.1 - 2.2e-108 363.1 0.0 4.2e-108 362.1 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFH40839.1 - 2.3e-35 120.6 0.0 4.4e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFH40839.1 - 2.5e-05 23.9 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain RNA_pol_Rpb5_C PF01191.19 KFH40840.1 - 1.8e-33 114.2 1.0 3.5e-33 113.3 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFH40840.1 - 1.6e-26 92.7 0.0 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KFH40840.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease SH3_9 PF14604.6 KFH40841.1 - 1e-07 31.7 0.1 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFH40841.1 - 0.017 14.8 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KFH40841.1 - 0.019 14.6 1.4 0.036 13.7 1.4 1.5 1 0 0 1 1 1 0 SH3 domain adh_short_C2 PF13561.6 KFH40844.1 - 9.6e-45 153.0 0.6 1.2e-44 152.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH40844.1 - 2.5e-41 141.3 0.7 4.1e-41 140.6 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFH40844.1 - 6.5e-11 42.5 0.7 1e-10 41.8 0.7 1.2 1 0 0 1 1 1 1 KR domain GNAT_like PF18407.1 KFH40844.1 - 3.6 8.0 6.1 2.1 8.8 0.4 2.8 2 1 0 2 2 2 0 GCN5-related N-acetyltransferase like domain HEAT_EZ PF13513.6 KFH40845.1 - 3.6e-32 110.4 8.8 9.6e-16 57.9 0.0 9.4 7 1 3 10 10 10 5 HEAT-like repeat HEAT PF02985.22 KFH40845.1 - 2.3e-24 83.3 15.2 0.00011 22.1 0.0 10.3 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.6 KFH40845.1 - 1e-20 73.9 1.3 0.00081 19.7 0.1 6.9 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KFH40845.1 - 1.8e-10 41.1 0.4 0.24 11.4 0.0 4.9 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFH40845.1 - 3e-09 37.4 0.0 0.17 12.5 0.0 6.4 6 1 1 7 7 6 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KFH40845.1 - 9.9e-08 31.8 1.0 1e-05 25.3 0.0 4.7 5 1 0 5 5 5 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KFH40845.1 - 4.6e-07 29.3 7.0 0.12 11.5 0.0 5.3 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KFH40845.1 - 0.00092 17.9 2.0 0.059 11.9 0.0 3.3 3 1 0 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 KFH40845.1 - 0.0091 16.2 0.1 0.23 11.7 0.0 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KFH40845.1 - 0.0091 16.6 7.7 0.94 10.3 0.0 5.4 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat Arm PF00514.23 KFH40845.1 - 0.016 15.2 11.9 0.93 9.6 0.0 5.8 8 1 0 8 8 7 0 Armadillo/beta-catenin-like repeat DUF4303 PF14136.6 KFH40845.1 - 0.037 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Herpes_TAF50 PF03326.13 KFH40845.1 - 0.037 12.7 0.2 0.38 9.3 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) DUF3437 PF11919.8 KFH40845.1 - 0.043 13.7 0.2 11 6.0 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) DUF5578 PF17741.1 KFH40845.1 - 0.085 12.3 0.4 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5578) RIX1 PF08167.12 KFH40845.1 - 0.44 10.3 2.4 95 2.6 0.0 4.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis SPRY PF00622.28 KFH40846.1 - 2.5e-19 69.6 0.0 4.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Phage_fiber PF03335.13 KFH40846.1 - 0.061 13.5 2.8 0.22 11.7 2.8 2.0 1 0 0 1 1 1 0 Phage tail fibre repeat DUF5427 PF10310.9 KFH40847.1 - 1.9 7.4 15.2 2.2 7.2 14.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5427) Med19 PF10278.9 KFH40847.1 - 3.2 7.6 8.2 1.2 9.1 4.3 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 N2227 PF07942.12 KFH40848.1 - 1.4e-93 313.0 0.0 1.7e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KFH40848.1 - 0.0042 16.9 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40848.1 - 0.012 16.3 0.0 0.031 14.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40848.1 - 0.015 16.0 0.0 0.076 13.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_C12 PF01088.21 KFH40849.1 - 6.6e-69 231.9 0.0 8.1e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFH40849.1 - 6e-10 38.9 0.4 1.4e-09 37.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 KFH40850.1 - 5.2e-05 23.3 8.5 9.5e-05 22.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH40850.1 - 0.0059 15.5 0.1 0.0099 14.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tmemb_cc2 PF10267.9 KFH40853.1 - 0.02 14.1 0.3 0.04 13.1 0.3 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FapA PF03961.13 KFH40853.1 - 0.14 10.7 0.1 0.26 9.8 0.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 KFH40853.1 - 2.4 8.2 7.3 0.1 12.7 0.4 2.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CC2-LZ PF16516.5 KFH40853.1 - 2.9 8.3 7.1 30 5.0 0.7 3.3 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_2 PF01920.20 KFH40853.1 - 3.2 7.7 6.2 0.9 9.5 0.3 2.8 3 0 0 3 3 3 0 Prefoldin subunit ZapB PF06005.12 KFH40853.1 - 6 7.4 8.7 0.15 12.5 0.5 2.6 3 0 0 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 KFH40853.1 - 6.5 6.7 11.8 4 7.4 0.2 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion HHH_9 PF17674.1 KFH40854.1 - 0.11 13.4 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 HHH domain PAC4 PF16093.5 KFH40855.1 - 2e-20 72.8 0.1 2.6e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 KFH40855.1 - 0.032 14.2 0.0 0.093 12.7 0.0 1.6 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 BRCA-2_OB1 PF09103.10 KFH40856.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 ADH_zinc_N PF00107.26 KFH40857.1 - 1.1e-12 48.0 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH40857.1 - 0.00013 21.8 0.0 0.00046 20.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH40857.1 - 0.00053 21.0 0.0 0.0017 19.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KFH40857.1 - 0.044 12.9 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_N_2 PF16884.5 KFH40857.1 - 0.078 12.9 0.1 2.6 8.0 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Band_7 PF01145.25 KFH40858.1 - 2.8e-14 53.5 0.0 2.8e-14 53.5 0.0 4.0 2 2 1 3 3 3 1 SPFH domain / Band 7 family Glyco_trans_4_5 PF16994.5 KFH40858.1 - 0.14 11.7 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl-transferase family 4 Fringe PF02434.16 KFH40859.1 - 2.9e-07 30.2 0.0 7.9e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Fringe-like DUF604 PF04646.12 KFH40859.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF604 OmpW PF03922.14 KFH40859.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 OmpW family MFS_1 PF07690.16 KFH40860.1 - 2e-18 66.5 30.8 3.8e-16 59.0 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KFH40860.1 - 0.0013 18.3 9.8 0.005 16.3 0.6 3.0 3 0 0 3 3 3 2 Nodulin-like DUF4516 PF14990.6 KFH40860.1 - 0.012 15.3 0.8 0.012 15.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Vault_3 PF17795.1 KFH40860.1 - 0.18 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein Repeat domain DUF3392 PF11872.8 KFH40860.1 - 1.9 8.8 14.1 0.33 11.2 0.3 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3392) 7tm_7 PF08395.12 KFH40860.1 - 2.9 7.0 5.7 0.79 8.9 0.2 2.3 3 0 0 3 3 3 0 7tm Chemosensory receptor Epimerase PF01370.21 KFH40862.1 - 4.7e-18 65.5 0.0 3.9e-17 62.5 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH40862.1 - 1.3e-14 54.3 0.2 8.1e-07 28.7 1.5 3.8 2 1 1 3 3 3 3 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFH40862.1 - 3.6e-11 42.7 0.5 2.5e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFH40862.1 - 4e-07 29.5 0.5 0.0012 18.1 0.0 3.0 1 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFH40862.1 - 7.5e-06 25.2 0.0 3.2e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFH40862.1 - 3.7e-05 22.9 0.0 0.0006 18.9 0.0 2.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F-box PF00646.33 KFH40863.1 - 0.39 10.6 2.7 0.84 9.6 0.5 2.1 1 1 1 2 2 2 0 F-box domain Glycophorin_A PF01102.18 KFH40864.1 - 0.089 13.0 0.6 0.11 12.7 0.6 1.2 1 0 0 1 1 1 0 Glycophorin A HpcH_HpaI PF03328.14 KFH40865.1 - 9.4e-27 93.6 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Dicty_REP PF05086.12 KFH40866.1 - 0.21 9.5 0.3 0.25 9.3 0.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRO1 PF03097.18 KFH40867.1 - 5.3e-120 400.8 0.0 9.3e-120 400.0 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFH40867.1 - 3.3e-80 269.5 9.0 3.3e-80 269.5 9.0 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV K-box PF01486.17 KFH40867.1 - 0.094 12.9 0.0 0.094 12.9 0.0 2.9 3 0 0 3 3 3 0 K-box region DUF2789 PF10982.8 KFH40867.1 - 0.099 12.8 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Myb_DNA-bind_3 PF12776.7 KFH40867.1 - 0.72 10.9 3.4 5.5 8.1 1.2 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain F-box PF00646.33 KFH40868.1 - 1.3e-06 28.1 1.2 2.3e-06 27.3 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFH40868.1 - 7.5e-05 22.6 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like Inositol_P PF00459.25 KFH40869.1 - 4.8e-34 118.1 0.0 2.4e-33 115.8 0.0 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family GST_C_3 PF14497.6 KFH40871.1 - 1.3e-28 99.1 0.0 2.1e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH40871.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH40871.1 - 0.0093 16.2 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFH40871.1 - 0.082 13.3 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.27 KFH40872.1 - 4.7e-36 123.9 0.0 1.2e-35 122.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KFH40872.1 - 1.6e-29 101.8 37.3 1.6e-11 44.2 6.1 4.9 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 KFH40872.1 - 0.042 13.4 0.0 0.18 11.4 0.0 2.1 1 0 0 1 1 1 0 Zinc finger domain zf-UBR PF02207.20 KFH40873.1 - 6.7e-18 64.6 16.7 6.7e-18 64.6 16.7 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KFH40873.1 - 1e-06 28.4 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Nefa_Nip30_N PF10187.9 KFH40874.1 - 3.6e-30 104.4 24.7 6e-30 103.7 24.0 1.8 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 RAP1 PF07218.11 KFH40874.1 - 0.24 9.6 6.4 0.31 9.3 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ASFV_J13L PF05568.11 KFH40874.1 - 0.25 11.1 2.5 0.41 10.4 2.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Hamartin PF04388.12 KFH40874.1 - 0.38 9.4 3.5 0.46 9.1 3.5 1.1 1 0 0 1 1 1 0 Hamartin protein BAF1_ABF1 PF04684.13 KFH40874.1 - 0.55 9.2 10.0 0.78 8.7 10.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3886 PF13025.6 KFH40874.1 - 0.86 9.8 22.8 3 8.1 4.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) FliE PF02049.18 KFH40874.1 - 8 6.7 8.8 2.5 8.3 5.4 2.0 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE AAA PF00004.29 KFH40875.1 - 6.5e-43 146.3 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFH40875.1 - 1.6e-12 47.2 0.1 1e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFH40875.1 - 1.2e-10 41.0 0.1 2.5e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFH40875.1 - 5.8e-08 33.3 0.0 6.7e-05 23.3 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFH40875.1 - 1.6e-06 28.1 0.1 3.8e-05 23.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH40875.1 - 3.8e-06 27.1 0.0 9.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFH40875.1 - 6.8e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH40875.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KFH40875.1 - 0.0003 20.0 0.0 0.00076 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFH40875.1 - 0.0005 20.6 0.1 0.0023 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFH40875.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KFH40875.1 - 0.0022 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KFH40875.1 - 0.0029 17.2 0.0 0.008 15.8 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 KFH40875.1 - 0.003 17.6 0.1 0.0097 15.9 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KFH40875.1 - 0.0036 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFH40875.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KFH40875.1 - 0.0053 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFH40875.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KFH40875.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFH40875.1 - 0.0087 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KFH40875.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KFH40875.1 - 0.014 15.2 0.8 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFH40875.1 - 0.018 14.7 0.0 0.057 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFH40875.1 - 0.039 13.3 0.5 0.13 11.5 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KFH40875.1 - 0.039 13.7 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KFH40875.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KFH40875.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KFH40875.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH40875.1 - 0.098 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Trimer_CC PF08954.11 KFH40875.1 - 0.1 12.2 0.3 0.25 10.9 0.3 1.7 1 0 0 1 1 1 0 Trimerisation motif AAA_25 PF13481.6 KFH40875.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFH40875.1 - 0.11 12.9 1.9 15 6.0 1.7 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KFH40875.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HMG_box_2 PF09011.10 KFH40876.1 - 4.2e-10 40.1 6.4 5.3e-06 26.9 4.4 3.4 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KFH40876.1 - 2.7e-07 30.9 1.8 2.7e-07 30.9 1.8 4.1 4 2 1 5 5 5 2 HMG (high mobility group) box SET PF00856.28 KFH40876.1 - 9.9 6.5 10.9 2.2e+03 -1.1 10.9 2.3 1 1 0 1 1 1 0 SET domain 3Beta_HSD PF01073.19 KFH40877.1 - 3.3e-68 229.7 0.0 4.3e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH40877.1 - 4.8e-32 111.3 0.1 6.7e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFH40877.1 - 2.9e-17 62.7 0.1 3.7e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFH40877.1 - 1.1e-13 51.3 0.0 5e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFH40877.1 - 4e-13 49.7 0.0 5.7e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFH40877.1 - 5.9e-12 45.3 0.0 9.8e-10 38.0 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFH40877.1 - 8.3e-07 28.4 3.6 1e-06 28.1 0.7 2.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 KFH40877.1 - 0.0053 16.7 1.3 0.095 12.6 1.3 2.3 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 KFH40877.1 - 0.026 14.6 0.0 0.069 13.3 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SH3_10 PF17902.1 KFH40877.1 - 0.21 11.7 0.3 77 3.5 0.0 3.4 2 1 1 3 3 3 0 SH3 domain UCR_UQCRX_QCR9 PF05365.12 KFH40878.1 - 3.5e-24 84.5 4.2 3.9e-24 84.4 4.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2417 PF10329.9 KFH40879.1 - 4.1e-85 285.0 0.8 5.6e-85 284.5 0.8 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) TMEM82 PF15816.5 KFH40879.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 Abhydrolase_1 PF00561.20 KFH40879.1 - 0.047 13.3 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold K_trans PF02705.16 KFH40879.1 - 0.067 11.7 5.6 0.095 11.2 5.6 1.2 1 0 0 1 1 1 0 K+ potassium transporter DUF4267 PF14087.6 KFH40879.1 - 0.29 11.2 3.5 0.78 9.8 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) DUF2070 PF09843.9 KFH40879.1 - 0.61 8.3 11.7 0.85 7.8 11.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CRC_subunit PF08624.10 KFH40880.1 - 6.2e-53 178.8 0.0 1.1e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit MSA_2 PF00985.17 KFH40880.1 - 8.9 6.6 8.1 18 5.6 8.1 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Cyclin PF08613.11 KFH40881.1 - 3.1e-09 37.4 0.0 5.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFH40881.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Proteasome PF00227.26 KFH40882.1 - 1.5e-31 109.4 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Mago-bind PF09282.10 KFH40883.1 - 7.2e-15 54.5 2.4 1.4e-14 53.6 2.4 1.5 1 0 0 1 1 1 1 Mago binding His_Phos_2 PF00328.22 KFH40886.1 - 4.7e-16 59.1 0.0 3.2e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) eIF-6 PF01912.18 KFH40887.1 - 6.2e-78 260.7 0.3 9.3e-78 260.1 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family Methyltransf_31 PF13847.6 KFH40888.1 - 5.7e-13 48.9 0.0 3.7e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40888.1 - 1e-05 26.2 0.0 7.7e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH40888.1 - 2e-05 25.2 0.0 0.26 12.0 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40888.1 - 5e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40888.1 - 0.00016 22.2 0.0 0.19 12.4 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 KFH40888.1 - 0.0032 17.1 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 KFH40888.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 KFH40888.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain NOA36 PF06524.12 KFH40888.1 - 8.7 5.6 7.5 12 5.1 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein ANAPC4 PF12896.7 KFH40890.1 - 4.5e-68 228.8 0.0 6.7e-68 228.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KFH40890.1 - 5.1e-11 42.7 0.0 3.6e-10 40.0 0.0 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2420 PF10336.9 KFH40891.1 - 2.8e-08 33.7 1.1 0.00084 19.3 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2420) Ribosomal_S3_C PF00189.20 KFH40893.1 - 8.7e-25 87.1 0.2 4.8e-24 84.7 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFH40893.1 - 6.1e-12 45.2 0.1 1.1e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KFH40893.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KFH40893.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus RRM_1 PF00076.22 KFH40894.1 - 3.4e-38 129.3 0.1 4.1e-12 45.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH40894.1 - 4.8e-17 61.6 0.0 0.009 15.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KFH40894.1 - 1.3e-06 28.0 11.9 1.3e-06 28.0 11.9 4.0 3 1 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 KFH40894.1 - 5e-05 23.4 0.0 0.094 12.8 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 KFH40894.1 - 9.6e-05 22.3 0.0 0.12 12.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 KFH40894.1 - 0.0057 16.7 0.1 0.26 11.4 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 KFH40894.1 - 0.017 14.9 0.0 1.1 9.0 0.0 3.5 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KFH40894.1 - 0.07 13.1 0.0 22 5.1 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFH40894.1 - 0.16 12.0 0.5 0.76 9.8 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain HEAT PF02985.22 KFH40895.1 - 3.9e-41 135.5 12.9 0.016 15.4 0.0 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KFH40895.1 - 2.7e-33 114.2 6.7 4.9e-11 42.9 0.0 7.8 5 2 3 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 KFH40895.1 - 2.8e-13 50.0 6.6 0.028 14.9 0.0 9.2 10 1 1 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFH40895.1 - 1.8e-11 44.5 3.9 0.024 15.2 0.2 7.5 6 2 3 9 9 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFH40895.1 - 1.8e-08 34.6 13.5 0.00058 19.9 0.1 6.5 5 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFH40895.1 - 5.6e-08 31.8 5.8 0.0084 14.7 0.2 5.2 4 1 1 5 5 5 3 Adaptin N terminal region RTP1_C1 PF10363.9 KFH40895.1 - 7.1e-07 29.4 4.3 0.029 14.6 0.1 5.2 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFH40895.1 - 1.5e-06 28.0 2.5 0.046 13.3 0.0 4.4 4 1 1 5 5 5 3 CLASP N terminal Arm PF00514.23 KFH40895.1 - 0.0075 16.3 0.5 2.8 8.1 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RhoGAP PF00620.27 KFH40895.1 - 0.034 14.0 0.4 0.14 12.0 0.1 2.1 2 1 1 3 3 3 0 RhoGAP domain M11L PF11099.8 KFH40895.1 - 0.085 13.1 0.2 14 5.9 0.0 3.4 2 1 2 4 4 4 0 Apoptosis regulator M11L like Ecm29 PF13001.7 KFH40895.1 - 0.16 10.6 3.6 2.3 6.8 0.0 3.5 3 1 1 4 4 4 0 Proteasome stabiliser Proteasom_PSMB PF10508.9 KFH40895.1 - 0.17 10.4 2.2 0.36 9.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit tRNA_synthFbeta PF17759.1 KFH40896.1 - 9.6e-46 155.9 0.0 1.4e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFH40896.1 - 3.8e-32 110.3 0.3 1.1e-30 105.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFH40896.1 - 2.1e-24 86.1 0.1 3.4e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFH40896.1 - 5e-16 58.8 0.0 2.1e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain SPRY PF00622.28 KFH40896.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 SPRY domain LCAT PF02450.15 KFH40897.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KFH40897.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KFH40897.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFH40897.1 - 4.8 7.7 13.6 0.092 13.3 4.9 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Gtr1_RagA PF04670.12 KFH40898.1 - 3.4e-69 232.7 0.1 4.3e-69 232.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFH40898.1 - 0.0009 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFH40898.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFH40898.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFH40898.1 - 0.027 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFH40898.1 - 0.035 14.5 0.0 0.098 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Adap_comp_sub PF00928.21 KFH40899.1 - 8.9e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFH40899.1 - 2.9e-08 33.8 0.0 4.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KFH40899.1 - 0.014 15.8 0.3 0.028 14.8 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Mg_trans_NIPA PF05653.14 KFH40900.1 - 1.2e-102 343.0 15.3 1.4e-102 342.8 15.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFH40900.1 - 3.1e-05 24.1 5.7 3.1e-05 24.1 5.7 3.3 3 0 0 3 3 3 2 EamA-like transporter family Myotub-related PF06602.14 KFH40901.1 - 1.2e-148 494.8 0.0 1.9e-148 494.1 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain ADH_zinc_N_2 PF13602.6 KFH40902.1 - 1.1e-19 71.8 0.0 2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH40902.1 - 3e-14 53.1 0.0 5.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH40902.1 - 5.1e-08 32.8 0.5 1.2e-06 28.3 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KFH40902.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3937 PF13073.6 KFH40904.1 - 2.2 8.5 4.9 1.2 9.3 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3937) Ferric_reduct PF01794.19 KFH40905.1 - 2.3e-23 82.7 17.8 2.3e-23 82.7 17.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFH40905.1 - 2.3e-10 40.5 0.0 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KFH40905.1 - 1.4e-07 31.8 0.0 4.7e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KFH40905.1 - 0.14 12.8 0.0 0.63 10.7 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Abhydrolase_1 PF00561.20 KFH40907.1 - 1.4e-21 77.3 0.1 3.8e-18 66.1 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH40907.1 - 1.7e-14 54.9 1.5 2.4e-14 54.5 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH40907.1 - 5.4e-13 48.8 0.0 7.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFH40907.1 - 0.046 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KFH40907.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KFH40907.1 - 0.24 11.2 0.0 1.5 8.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Sugar_tr PF00083.24 KFH40908.1 - 4.4e-117 391.7 25.1 5.1e-117 391.5 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH40908.1 - 6e-19 68.2 41.1 4.7e-16 58.7 28.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH40908.1 - 0.00025 20.0 10.3 0.042 12.7 2.1 3.0 2 2 0 2 2 2 2 MFS_1 like family Rtf2 PF04641.12 KFH40909.1 - 6.1e-52 176.6 1.2 1.4e-51 175.4 1.2 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KFH40909.1 - 0.00076 19.3 0.2 0.0029 17.4 0.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFH40909.1 - 0.00088 19.2 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFH40909.1 - 0.0015 18.9 0.1 0.0028 17.9 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH40909.1 - 0.0024 17.9 0.0 0.0072 16.3 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFH40909.1 - 0.0072 16.1 0.7 0.013 15.3 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH40909.1 - 0.0078 15.9 0.6 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger Zn-ribbon_8 PF09723.10 KFH40909.1 - 0.015 15.4 1.4 0.041 14.0 1.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF3464 PF11947.8 KFH40909.1 - 0.028 14.2 2.5 0.042 13.6 2.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-C3HC4 PF00097.25 KFH40909.1 - 0.029 14.2 0.2 0.056 13.3 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFH40909.1 - 0.032 14.0 0.2 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFH40909.1 - 0.045 13.5 0.2 0.076 12.8 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PRTP PF01366.18 KFH40909.1 - 0.087 10.9 3.4 0.11 10.5 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein YhfH PF14149.6 KFH40909.1 - 0.093 12.7 0.6 0.093 12.7 0.6 1.9 2 1 0 2 2 1 0 YhfH-like protein zf-C3HC4_3 PF13920.6 KFH40909.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vfa1 PF08432.10 KFH40909.1 - 0.18 12.1 8.4 0.26 11.6 8.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DASH_Spc19 PF08287.11 KFH40909.1 - 0.27 11.1 7.9 0.45 10.4 7.9 1.4 1 0 0 1 1 1 0 Spc19 FancD2 PF14631.6 KFH40909.1 - 0.36 8.2 5.4 0.45 7.8 5.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease UPF0547 PF10571.9 KFH40909.1 - 1 9.5 3.4 3.7 7.7 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FYDLN_acid PF09538.10 KFH40909.1 - 1.9 9.2 11.4 6.8 7.4 11.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 KFH40909.1 - 3.4 7.3 5.9 5.5 6.6 5.9 1.3 1 0 0 1 1 1 0 FAM176 family Zn_clus PF00172.18 KFH40910.1 - 6.6e-08 32.5 8.7 1.1e-07 31.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STALD PF18185.1 KFH40911.1 - 1.3 8.3 7.6 10 5.4 0.0 3.7 4 0 0 4 4 4 0 Sir2- and TIR-associating SLOG family Hist_rich_Ca-bd PF10529.9 KFH40912.1 - 3.6 7.9 7.8 0.27 11.5 3.0 1.6 2 0 0 2 2 2 0 Histidine-rich Calcium-binding repeat region ketoacyl-synt PF00109.26 KFH40913.1 - 3.8e-64 216.7 1.8 8.8e-54 182.7 1.4 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH40913.1 - 6.2e-61 205.4 0.1 1.4e-60 204.3 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH40913.1 - 9.5e-48 162.9 0.0 2.1e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH40913.1 - 1.1e-43 150.0 0.0 2.3e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH40913.1 - 2.1e-39 134.2 0.0 5.8e-39 132.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH40913.1 - 5.9e-19 69.4 1.0 1.9e-16 61.3 0.1 4.2 5 0 0 5 5 4 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH40913.1 - 1.1e-18 67.8 0.0 2.7e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH40913.1 - 2.8e-15 56.7 0.0 2e-11 44.3 0.1 2.6 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KFH40913.1 - 7.3e-14 51.9 1.8 6.2e-13 48.9 0.8 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFH40913.1 - 3.8e-10 39.5 0.6 3.2e-08 33.2 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFH40913.1 - 4.3e-10 40.2 0.0 1.9e-09 38.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40913.1 - 5.8e-09 36.0 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40913.1 - 2.9e-08 34.2 0.0 1.1e-07 32.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40913.1 - 6.5e-07 29.3 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFH40913.1 - 1e-06 28.9 0.1 4.7e-06 26.9 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFH40913.1 - 1.3e-05 24.7 2.1 5e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KFH40913.1 - 0.00015 21.2 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SAT PF16073.5 KFH40913.1 - 0.014 15.1 0.6 0.063 13.0 0.6 1.9 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_2 PF00891.18 KFH40913.1 - 0.041 13.2 0.1 0.13 11.5 0.1 1.8 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KFH40913.1 - 0.18 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase FAT PF02259.23 KFH40914.1 - 4.1e-131 437.3 9.7 9.8e-131 436.1 9.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KFH40914.1 - 6.8e-75 252.1 0.1 1.3e-74 251.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KFH40914.1 - 1.4e-68 229.9 2.8 1.6e-65 220.0 0.5 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KFH40914.1 - 5.5e-46 155.0 3.4 1.6e-45 153.5 0.2 3.6 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KFH40914.1 - 2.4e-14 52.2 18.8 0.14 12.5 0.0 11.7 13 0 0 13 13 11 4 HEAT repeat FATC PF02260.20 KFH40914.1 - 4.3e-13 48.8 0.1 1.6e-12 47.0 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KFH40914.1 - 4e-12 46.4 13.9 0.015 15.7 0.1 9.5 9 1 0 9 9 9 3 HEAT repeats Cnd1 PF12717.7 KFH40914.1 - 4e-12 46.5 2.4 0.008 16.2 0.0 7.1 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFH40914.1 - 1.2e-08 35.3 11.6 0.033 14.7 0.0 10.3 8 3 3 11 11 10 2 HEAT-like repeat Adaptin_N PF01602.20 KFH40914.1 - 3.3e-07 29.3 6.0 0.0073 14.9 0.0 4.9 5 1 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFH40914.1 - 5.6e-07 30.1 0.2 4.6 7.9 0.0 6.8 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KFH40914.1 - 0.00015 21.0 0.0 0.071 12.2 0.0 3.6 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) DUF1041 PF06292.17 KFH40914.1 - 0.048 14.1 0.3 11 6.5 0.1 3.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1041) VirDNA-topo-I_N PF09266.10 KFH40914.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Cohesin_HEAT PF12765.7 KFH40914.1 - 0.088 13.1 0.1 52 4.3 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DNA_primase_S PF01896.19 KFH40915.1 - 4e-65 219.2 0.2 5.5e-65 218.7 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit Epimerase PF01370.21 KFH40916.1 - 1.5e-19 70.4 0.0 2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH40916.1 - 9.8e-14 51.5 0.1 5.1e-13 49.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFH40916.1 - 1.8e-13 50.1 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFH40916.1 - 2.6e-09 36.6 0.0 1.2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFH40916.1 - 2.4e-08 33.5 0.1 3e-05 23.3 0.1 2.7 1 1 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.23 KFH40916.1 - 0.00032 20.8 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFH40916.1 - 0.00047 20.1 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KFH40917.1 - 2.9e-50 170.1 0.0 3.7e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH40917.1 - 1.2e-16 60.6 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFH40917.1 - 0.00017 21.8 0.1 0.00047 20.4 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFH40917.1 - 0.03 13.9 0.1 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Zip PF02535.22 KFH40918.1 - 2.4e-32 112.5 46.6 1.1e-14 54.4 4.5 4.1 3 1 1 4 4 4 4 ZIP Zinc transporter HAD_SAK_1 PF10307.9 KFH40919.1 - 1.8e-78 263.0 0.0 2.8e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Carb_anhydrase PF00194.21 KFH40920.1 - 2.9e-29 102.4 0.0 1.4e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase tRNA_m1G_MT PF01746.21 KFH40921.1 - 9.1e-25 87.5 0.0 8.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase HSF_DNA-bind PF00447.17 KFH40922.1 - 1.3e-24 86.6 0.4 2.6e-24 85.6 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KFH40922.1 - 3.5e-24 85.1 0.0 8.1e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain YabA PF06156.13 KFH40922.1 - 0.049 14.3 1.1 0.049 14.3 1.1 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Sec34 PF04136.15 KFH40922.1 - 0.16 11.8 2.4 0.34 10.8 2.2 1.6 1 1 0 1 1 1 0 Sec34-like family SUIM_assoc PF16619.5 KFH40922.1 - 2.8 8.1 12.7 0.22 11.6 5.0 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MutS_V PF00488.21 KFH40924.1 - 9.6e-84 280.1 0.1 1.5e-83 279.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFH40924.1 - 6.2e-38 131.0 0.4 2.3e-37 129.1 0.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFH40924.1 - 3.6e-22 79.1 1.5 9.2e-22 77.8 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KFH40924.1 - 7.7e-20 71.2 0.0 5e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KFH40924.1 - 8.3e-14 51.7 1.6 3.9e-13 49.6 0.4 2.9 3 0 0 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 KFH40924.1 - 0.071 12.7 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAD PF02938.14 KFH40924.1 - 0.087 13.1 0.2 0.32 11.3 0.2 1.9 1 0 0 1 1 1 0 GAD domain AAA_23 PF13476.6 KFH40924.1 - 0.21 12.1 1.3 8.4 6.8 0.0 2.9 3 1 0 3 3 3 0 AAA domain FMN_dh PF01070.18 KFH40925.1 - 8.3e-119 396.7 0.0 1e-118 396.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFH40925.1 - 2.2e-18 66.2 0.0 4.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KFH40925.1 - 8.4e-07 28.7 0.2 1.4e-05 24.6 0.2 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 KFH40925.1 - 4.4e-05 22.8 0.1 7.2e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFH40925.1 - 7.2e-05 21.9 0.2 0.00026 20.1 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KFH40925.1 - 0.013 14.8 0.0 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG W2 PF02020.18 KFH40926.1 - 4e-10 39.7 0.1 1.3e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFH40926.1 - 1.2e-07 31.1 8.7 0.00032 20.3 3.5 3.7 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFH40926.1 - 7.5e-05 21.1 0.6 0.00011 20.5 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KFH40926.1 - 0.0028 18.0 0.1 0.0081 16.5 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KFH40926.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KFH40926.1 - 0.29 10.0 1.4 0.96 8.3 1.4 1.8 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 KFH40926.1 - 0.31 10.8 8.7 0.31 10.8 1.8 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KFH40927.1 - 1.3e-29 103.3 37.6 1.3e-29 103.3 37.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Tim17 PF02466.19 KFH40928.1 - 0.0014 19.0 4.8 0.0044 17.4 4.6 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF1269 PF06897.12 KFH40928.1 - 0.0066 16.7 1.4 0.33 11.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 KFH40928.1 - 3.1 8.0 8.9 2.2 8.5 1.6 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Zn_clus PF00172.18 KFH40929.1 - 1.8e-05 24.7 9.0 2.7e-05 24.2 9.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KFH40930.1 - 1.7e-73 247.7 0.0 2.6e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KFH40930.1 - 7.8e-73 245.2 0.1 2.2e-72 243.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH40930.1 - 1.1e-47 162.2 0.0 2.3e-43 148.2 0.0 3.0 3 0 0 3 3 2 2 KR domain PS-DH PF14765.6 KFH40930.1 - 5.4e-47 160.5 0.2 9.5e-47 159.7 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 KFH40930.1 - 1.8e-46 158.8 0.0 2.8e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 KFH40930.1 - 4.4e-44 151.3 1.9 5.7e-44 150.9 0.3 2.0 3 0 0 3 3 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH40930.1 - 7.1e-32 109.9 0.0 2.9e-31 107.9 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFH40930.1 - 3.2e-19 69.1 0.0 6.4e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Methyltransf_12 PF08242.12 KFH40930.1 - 1.4e-17 64.3 0.0 4.5e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH40930.1 - 5.6e-16 59.0 0.0 1.9e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KFH40930.1 - 1.9e-13 50.6 0.4 1.6e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KFH40930.1 - 1.8e-12 47.8 0.0 8.6e-12 45.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40930.1 - 5.5e-11 43.0 0.0 2.1e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KFH40930.1 - 6.1e-11 42.3 0.0 3.8e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KFH40930.1 - 4.7e-10 39.2 0.0 6.2e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_23 PF13489.6 KFH40930.1 - 3.2e-09 36.8 0.0 8.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KFH40930.1 - 1.3e-07 31.7 0.8 4e-05 23.6 0.0 3.7 4 0 0 4 4 4 1 NAD(P)H-binding Methyltransf_31 PF13847.6 KFH40930.1 - 1.2e-06 28.4 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH40930.1 - 1.7e-05 24.3 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RmlD_sub_bind PF04321.17 KFH40930.1 - 6e-05 22.3 0.0 0.00017 20.8 0.0 1.8 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 KFH40930.1 - 0.00024 21.5 0.0 0.016 15.7 0.0 3.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Thiolase_N PF00108.23 KFH40930.1 - 0.00054 19.4 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KFH40930.1 - 0.0025 17.4 0.0 0.0087 15.6 0.0 2.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KFH40930.1 - 0.0096 16.9 0.2 0.15 13.0 0.1 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DapB_N PF01113.20 KFH40930.1 - 0.047 13.8 0.0 0.97 9.6 0.0 3.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Aminotran_1_2 PF00155.21 KFH40931.1 - 2.3e-48 165.2 0.0 2.6e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Torus PF16131.5 KFH40931.1 - 0.14 12.9 0.4 0.14 12.9 0.4 1.6 2 0 0 2 2 2 0 Torus domain WD40 PF00400.32 KFH40933.1 - 6.3e-113 365.5 54.9 1.8e-11 44.4 0.4 12.3 12 0 0 12 12 11 11 WD domain, G-beta repeat NACHT_N PF17100.5 KFH40933.1 - 4.7e-57 193.4 0.0 9.2e-57 192.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KFH40933.1 - 2.2e-38 130.4 5.2 0.0031 17.8 0.0 11.5 2 1 9 11 11 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH40933.1 - 1.9e-20 73.1 40.2 6.9e-05 22.0 3.6 11.2 1 1 7 8 8 8 7 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KFH40933.1 - 3.5e-17 62.8 0.0 8.2e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KFH40933.1 - 1.8e-16 60.6 2.3 0.011 15.7 0.2 5.9 2 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFH40933.1 - 2.1e-13 49.8 9.9 4.8 7.2 0.1 10.7 11 0 0 11 11 10 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KFH40933.1 - 5.7e-10 39.0 0.0 0.26 10.6 0.0 5.6 4 1 2 6 6 6 2 WD40-like domain Cytochrom_D1 PF02239.16 KFH40933.1 - 8.2e-08 31.2 0.3 0.11 11.0 0.0 4.7 1 1 4 5 5 5 3 Cytochrome D1 heme domain Nup160 PF11715.8 KFH40933.1 - 1.4e-07 30.6 6.2 5.8 5.4 0.0 8.3 3 2 1 9 9 9 1 Nucleoporin Nup120/160 DUF5114 PF17141.4 KFH40933.1 - 4.8e-06 27.0 2.2 11 6.6 0.1 6.6 3 1 3 7 7 7 0 Domain of unknown function (DUF5114) Proteasome_A_N PF10584.9 KFH40933.1 - 6.6e-05 22.5 15.5 48 3.8 0.0 9.7 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature AAA_19 PF13245.6 KFH40933.1 - 0.00014 22.2 0.4 0.018 15.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFH40933.1 - 0.00016 22.0 0.6 0.51 10.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain Antifungal_pept PF11410.8 KFH40933.1 - 0.00018 21.3 27.9 2.6 8.0 0.3 8.1 7 0 0 7 7 7 2 Antifungal peptide PALB2_WD40 PF16756.5 KFH40933.1 - 0.00028 19.9 29.1 0.063 12.2 0.5 7.1 1 1 5 8 8 8 4 Partner and localizer of BRCA2 WD40 domain GTP_EFTU PF00009.27 KFH40933.1 - 0.0026 17.3 0.6 13 5.2 0.0 5.3 4 1 1 5 5 5 0 Elongation factor Tu GTP binding domain ResIII PF04851.15 KFH40933.1 - 0.0036 17.3 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFH40933.1 - 0.029 13.6 0.0 0.067 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) YdjO PF14169.6 KFH40933.1 - 0.033 13.9 35.2 11 5.8 0.3 8.7 8 0 0 8 8 8 0 Cold-inducible protein YdjO BLUF PF04940.12 KFH40933.1 - 0.058 13.5 0.0 81 3.4 0.0 5.5 9 0 0 9 9 4 0 Sensors of blue-light using FAD AAA_11 PF13086.6 KFH40933.1 - 0.09 12.5 0.6 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1936 PF09151.10 KFH40933.1 - 0.5 10.3 10.4 1.4e+02 2.5 0.0 6.5 7 0 0 7 7 7 0 Domain of unknown function (DUF1936) TruB_C PF09142.11 KFH40933.1 - 0.57 10.0 5.9 23 4.9 0.0 6.0 8 0 0 8 8 7 0 tRNA Pseudouridine synthase II, C terminal Syntaxin PF00804.25 KFH40933.1 - 1.2 8.7 7.9 0.11 12.1 1.6 2.1 2 0 0 2 2 2 0 Syntaxin Amidohydro_3 PF07969.11 KFH40934.1 - 2.6e-15 56.8 1.1 4.7e-10 39.5 0.1 3.3 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFH40934.1 - 3.1e-11 43.2 0.1 6.8e-10 38.8 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family Spt5_N PF11942.8 KFH40934.1 - 1.2 10.1 19.1 4.2 8.4 2.9 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BSP_II PF05432.11 KFH40934.1 - 2.1 8.0 10.6 1.2 8.7 1.6 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LigB PF02900.18 KFH40936.1 - 8.9e-33 113.5 0.0 1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_18 PF00704.28 KFH40939.1 - 9.2e-74 249.0 5.8 1.1e-73 248.7 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LisH_2 PF16045.5 KFH40939.1 - 0.084 11.9 0.9 0.28 10.3 0.6 1.9 2 0 0 2 2 2 0 LisH Tyrosinase PF00264.20 KFH40940.1 - 7.2e-50 170.3 1.0 1e-49 169.9 1.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase KR PF08659.10 KFH40941.1 - 4.6e-08 33.2 0.1 5e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KFH40941.1 - 0.0012 18.4 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldo_ket_red PF00248.21 KFH40942.1 - 1.4e-28 99.9 0.0 7.9e-28 97.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Phage_r1t_holin PF16945.5 KFH40942.1 - 0.012 15.8 0.2 0.55 10.4 0.1 2.3 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin MSV199 PF10553.9 KFH40942.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 MSV199 domain PLAC8 PF04749.17 KFH40943.1 - 8.5e-24 84.4 13.9 1.1e-23 84.1 13.9 1.1 1 0 0 1 1 1 1 PLAC8 family NPP1 PF05630.11 KFH40944.1 - 1.8e-58 197.9 3.5 2.1e-58 197.7 3.5 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_2_N PF02837.18 KFH40945.1 - 2.9e-12 46.8 0.4 1e-11 45.0 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFH40945.1 - 7.6e-12 44.9 0.4 5.3e-11 42.2 0.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KFH40945.1 - 3.2e-10 40.7 0.0 2.7e-09 37.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 FlgD_ig PF13860.6 KFH40945.1 - 0.079 12.8 1.4 0.17 11.7 1.4 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain Glyco_hydro2_C5 PF18565.1 KFH40945.1 - 0.13 12.1 0.6 0.3 10.9 0.6 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Big_1 PF02369.16 KFH40945.1 - 0.83 9.7 6.6 2.2 8.4 0.8 3.0 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 1) PIG-Y PF15159.6 KFH40946.1 - 1.3 10.0 6.4 4.9 8.1 6.4 2.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SDH_alpha PF03313.15 KFH40947.1 - 7.7e-101 337.1 0.4 9.7e-101 336.8 0.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KFH40947.1 - 1.6e-53 181.2 0.0 3.5e-53 180.1 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Peptidase_S8 PF00082.22 KFH40949.1 - 1.5e-29 103.2 14.8 2.6e-29 102.5 14.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH40949.1 - 2.2e-13 50.7 1.0 8.6e-13 48.8 1.0 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 KFH40951.1 - 1.1e-29 103.6 14.2 2.1e-29 102.7 14.1 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH40951.1 - 6.1e-10 39.6 0.1 7.9e-09 36.1 0.1 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 Galactosyl_T PF01762.21 KFH40953.1 - 1.8e-13 50.8 1.7 4.1e-12 46.3 1.7 2.1 1 1 0 1 1 1 1 Galactosyltransferase Phospholip_A2_3 PF09056.11 KFH40954.1 - 1.2e-43 148.2 0.5 1.7e-43 147.8 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF3562 PF12085.8 KFH40954.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Arrestin_C PF02752.22 KFH40955.1 - 1.2e-18 67.9 0.0 8.5e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFH40955.1 - 4.6e-12 46.2 0.0 7.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KFH40955.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like MWFE PF15879.5 KFH40956.1 - 1.2e-24 86.2 0.1 1.9e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Nup96 PF12110.8 KFH40957.1 - 6.7e-98 327.4 1.8 9.6e-98 326.9 1.8 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KFH40957.1 - 8.6e-53 178.5 0.0 1.8e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KFH40957.1 - 4e-23 82.1 346.1 6.8e-09 36.5 48.9 11.3 5 2 7 12 12 12 6 Nucleoporin FG repeat region Ribosomal_L7Ae PF01248.26 KFH40958.1 - 5.9e-22 77.2 1.0 1.2e-21 76.3 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KFH40958.1 - 0.1 11.6 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MOZ_SAS PF01853.18 KFH40961.1 - 9.6e-77 256.7 0.0 1.3e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFH40961.1 - 1.2e-20 72.9 3.0 2.3e-20 72.0 3.0 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KFH40961.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 KFH40961.1 - 0.18 11.9 12.0 0.036 14.2 2.3 2.8 1 1 1 2 2 2 0 PHD-finger EF_assoc_2 PF08356.12 KFH40962.1 - 4.4e-32 109.9 0.0 9.9e-32 108.8 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFH40962.1 - 4.2e-31 106.4 0.0 1e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KFH40962.1 - 1.1e-19 70.6 0.0 7.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH40962.1 - 9.6e-12 45.2 0.0 4.6e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KFH40962.1 - 4.2e-07 29.0 3.0 0.002 17.5 0.1 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KFH40962.1 - 9.9e-07 28.8 0.0 0.1 12.7 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFH40962.1 - 1.3e-06 28.5 0.0 0.0032 17.5 0.1 2.8 2 1 1 3 3 3 2 Dynamin family EF-hand_7 PF13499.6 KFH40962.1 - 7.7e-06 26.3 0.6 0.00083 19.8 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFH40962.1 - 9.9e-06 25.1 2.9 0.033 14.1 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 KFH40962.1 - 3e-05 24.5 0.0 0.029 14.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KFH40962.1 - 0.00014 21.5 0.0 0.01 15.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH40962.1 - 0.00065 20.0 0.0 0.057 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH40962.1 - 0.0013 19.0 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH40962.1 - 0.017 15.0 0.0 7.1 6.5 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA_24 PF13479.6 KFH40962.1 - 0.019 14.7 0.0 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KFH40962.1 - 0.02 14.8 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KFH40962.1 - 0.021 15.3 0.0 0.56 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KFH40962.1 - 0.029 13.9 0.0 42 3.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.6 KFH40962.1 - 0.063 13.1 1.0 0.11 12.3 0.1 1.9 2 0 0 2 2 1 0 EF hand EF-hand_5 PF13202.6 KFH40962.1 - 0.069 12.7 6.0 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 EF hand AAA_21 PF13304.6 KFH40962.1 - 0.081 12.7 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 KFH40962.1 - 0.099 12.4 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MCM PF00493.23 KFH40962.1 - 0.14 11.2 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain RNA_helicase PF00910.22 KFH40962.1 - 0.18 12.2 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase SET PF00856.28 KFH40963.1 - 0.0018 18.7 0.1 2 8.8 0.0 2.6 2 1 1 3 3 3 2 SET domain WD40 PF00400.32 KFH40964.1 - 1.1e-12 48.3 12.7 5.7e-06 27.0 0.2 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH40964.1 - 9.4e-10 38.7 0.1 0.00071 19.8 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH40964.1 - 0.00015 21.7 0.0 0.00058 19.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFH40964.1 - 0.0025 17.7 0.0 4.6 7.3 0.0 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KFH40964.1 - 0.003 15.6 0.0 0.0051 14.9 0.0 1.3 1 1 0 1 1 1 1 IKI3 family VID27 PF08553.10 KFH40964.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain ENTH PF01417.20 KFH40965.1 - 6.1e-49 165.2 0.0 9.3e-49 164.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KFH40965.1 - 1.1e-09 38.6 35.9 1.1e-09 38.6 35.9 5.6 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 KFH40965.1 - 0.0035 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.20 KFH40965.1 - 0.0057 16.5 4.4 0.1 12.6 0.2 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KFH40965.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 ANTH domain VHS PF00790.19 KFH40965.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 VHS domain EF-hand_7 PF13499.6 KFH40966.1 - 2.2e-17 63.3 5.6 9.3e-14 51.6 2.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFH40966.1 - 4.5e-14 52.0 9.3 4.2e-12 45.7 3.8 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFH40966.1 - 2.4e-13 48.6 7.3 3.6e-05 23.0 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFH40966.1 - 4e-12 45.0 4.5 0.0003 20.5 0.3 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFH40966.1 - 4.5e-08 32.2 2.2 0.00029 20.2 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KFH40966.1 - 4.5e-05 23.7 0.7 0.00047 20.4 0.5 2.4 2 1 0 2 2 2 1 EF-hand domain ATP_bind_3 PF01171.20 KFH40967.1 - 7.5e-18 64.9 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KFH40967.1 - 1.6e-16 59.5 3.6 1.6e-16 59.5 3.6 3.7 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KFH40967.1 - 0.051 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase NTF2 PF02136.20 KFH40968.1 - 1.6e-26 93.2 1.1 9.9e-25 87.4 1.1 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pox_MCEL PF03291.16 KFH40969.1 - 1.6e-70 237.9 0.0 1.5e-48 165.6 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KFH40969.1 - 2.7e-10 40.8 0.0 0.00018 22.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFH40969.1 - 1e-09 39.0 0.2 0.0024 18.6 0.0 2.7 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFH40969.1 - 3.9e-07 30.6 0.0 0.022 15.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFH40969.1 - 5.3e-07 29.5 0.0 0.00034 20.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFH40969.1 - 2.6e-05 24.1 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.6 KFH40969.1 - 4.1e-05 22.5 4.2 4.1e-05 22.5 4.2 1.5 2 0 0 2 2 2 1 Raftlin Methyltransf_4 PF02390.17 KFH40969.1 - 0.0067 15.9 0.1 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 KFH40969.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FAM92 PF06730.11 KFH40969.1 - 0.095 12.1 0.3 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 FAM92 protein MRNIP PF15749.5 KFH40969.1 - 0.63 10.8 4.5 1.8 9.3 4.5 1.8 1 0 0 1 1 1 0 MRN-interacting protein DUF2201_N PF13203.6 KFH40969.1 - 4.8 6.7 12.3 0.066 12.8 3.8 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Apolipoprotein PF01442.18 KFH40970.1 - 0.00042 20.2 2.3 0.0025 17.7 1.1 2.4 2 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain PH PF00169.29 KFH40970.1 - 0.0064 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 PH domain eRF1_3 PF03465.15 KFH40970.1 - 0.035 14.6 0.1 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 eRF1 domain 3 TssC PF17541.2 KFH40970.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB CK2S PF15011.6 KFH40970.1 - 0.16 11.9 0.1 0.52 10.2 0.0 1.9 2 1 0 2 2 2 0 Casein Kinase 2 substrate DUF4230 PF14014.6 KFH40970.1 - 0.21 11.8 0.6 3 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4230) Seipin PF06775.14 KFH40971.1 - 8.3e-57 192.5 0.1 1e-56 192.2 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) IFT43 PF15305.6 KFH40971.1 - 0.9 9.7 0.0 0.9 9.7 0.0 2.3 3 0 0 3 3 3 0 Intraflagellar transport protein 43 Clr5 PF14420.6 KFH40972.1 - 1.7e-17 63.4 2.0 2.5e-17 62.8 2.0 1.3 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_49N PF17433.2 KFH40973.1 - 9.9e-53 178.6 0.1 3e-52 177.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 KFH40973.1 - 3.1e-21 75.5 0.3 2.5e-19 69.4 0.1 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 IPU_b_solenoid PF18783.1 KFH40973.1 - 3.1e-19 68.7 2.3 3.1e-19 68.7 2.3 2.0 2 0 0 2 2 2 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 KFH40973.1 - 4.2e-18 65.3 5.0 1.2e-17 63.9 5.0 1.9 1 0 0 1 1 1 1 Beta solenoid repeat from Dextranase MFS_1 PF07690.16 KFH40974.1 - 6.7e-36 123.9 27.7 6.7e-36 123.9 27.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KFH40974.1 - 2.2 8.4 5.7 4.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage P21 holin S Fungal_trans_2 PF11951.8 KFH40975.1 - 5.8e-09 35.2 0.0 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH40975.1 - 0.0017 18.4 8.4 0.0045 17.1 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.16 KFH40977.1 - 4.7e-06 26.6 0.1 6.7e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ThaI PF15514.6 KFH40977.1 - 0.093 12.4 0.0 0.093 12.4 0.0 1.2 1 1 0 1 1 1 0 Restriction endonuclease ThaI DNA_primase_lrg PF04104.14 KFH40978.1 - 1.8e-83 280.0 0.0 2.6e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit adh_short PF00106.25 KFH40979.1 - 4.9e-34 117.5 0.0 9.1e-34 116.6 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH40979.1 - 2.1e-25 89.6 0.0 3.4e-25 89.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH40979.1 - 4.6e-05 23.0 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFH40979.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFH40979.1 - 0.022 14.1 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KFH40979.1 - 0.028 14.3 0.8 0.26 11.2 0.8 2.4 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 KFH40979.1 - 0.078 12.7 0.2 0.22 11.3 0.2 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.16 KFH40981.1 - 3.6e-35 121.5 29.7 3.6e-35 121.5 29.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH40981.1 - 2e-09 36.9 16.7 1.2e-08 34.3 17.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4112 PF13430.6 KFH40981.1 - 0.049 13.9 0.1 0.2 11.9 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) MreB_Mbl PF06723.13 KFH40981.1 - 0.07 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Zn_clus PF00172.18 KFH40982.1 - 6.3e-06 26.2 7.4 1.1e-05 25.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH40982.1 - 0.04 12.9 0.0 0.097 11.7 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain SUIM_assoc PF16619.5 KFH40982.1 - 0.43 10.7 9.0 5.6 7.1 6.5 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CoA_trans PF01144.23 KFH40984.1 - 2.3e-103 344.3 1.4 1.6e-62 210.7 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFH40984.1 - 9.6e-05 22.4 0.1 0.00018 21.4 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain NAD_binding_8 PF13450.6 KFH40984.1 - 0.064 13.5 0.1 0.22 11.8 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_60s PF00428.19 KFH40984.1 - 0.89 10.2 6.2 0.5 11.0 1.8 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein YjbR PF04237.13 KFH40985.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 YjbR zf-FPG_IleRS PF06827.14 KFH40986.1 - 0.015 15.1 2.1 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1660 PF07874.11 KFH40986.1 - 0.055 14.0 2.7 1.7 9.2 0.1 2.4 1 1 1 2 2 2 0 Prophage protein (DUF1660) zf-TFIIB PF13453.6 KFH40986.1 - 0.12 11.7 0.6 4 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Yippee-Mis18 PF03226.14 KFH40986.1 - 0.21 11.8 3.1 0.84 9.9 3.1 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Carla_C4 PF01623.17 KFH40986.1 - 0.81 9.7 5.4 4.2 7.4 1.1 2.1 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Chorion_2 PF03964.15 KFH40986.1 - 1.5 9.7 8.8 2.1 9.3 8.8 1.3 1 1 0 1 1 1 0 Chorion family 2 Hemerythrin PF01814.23 KFH40988.1 - 1.1e-11 45.5 2.7 1.7e-11 44.9 2.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Q_salvage PF10343.9 KFH40988.1 - 0.052 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family DUF4288 PF14119.6 KFH40988.1 - 0.86 10.1 3.5 2 8.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4288) DUF4690 PF15756.5 KFH40989.1 - 0.002 18.7 0.5 0.002 18.7 0.5 2.4 3 0 0 3 3 3 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 KFH40989.1 - 0.032 14.3 0.1 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 Podoplanin CD99L2 PF12301.8 KFH40989.1 - 0.26 11.6 5.2 0.33 11.2 4.2 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 CFEM PF05730.11 KFH40990.1 - 1.1e-15 57.4 9.3 1.4e-15 57.1 9.3 1.1 1 0 0 1 1 1 1 CFEM domain Abhydrolase_1 PF00561.20 KFH40991.1 - 7.5e-24 84.8 0.0 9.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH40991.1 - 1.7e-15 58.2 4.3 2.1e-15 57.9 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH40991.1 - 1.2e-08 34.5 0.0 3.5e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KFH40991.1 - 0.00063 19.4 0.0 1 8.9 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KFH40991.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 KFH40991.1 - 0.054 13.4 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 KFH40991.1 - 0.085 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family NUFIP1 PF10453.9 KFH40992.1 - 7.3e-08 32.1 0.1 2.4e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KFH40992.1 - 0.00091 19.2 5.7 0.0016 18.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger domain Mito_fiss_reg PF05308.11 KFH40992.1 - 0.0056 16.8 0.7 0.0056 16.8 0.7 5.0 4 2 0 4 4 4 1 Mitochondrial fission regulator zf-CCCH PF00642.24 KFH40992.1 - 0.055 13.4 5.2 0.11 12.5 5.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFH40992.1 - 0.093 13.2 3.4 0.19 12.3 3.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FlbT PF07378.11 KFH40992.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlbT PFK PF00365.20 KFH40993.1 - 3.1e-187 620.6 1.8 1.2e-104 349.6 1.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.8 KFH40993.1 - 1 9.1 4.3 5.5 6.7 0.1 3.4 4 0 0 4 4 4 0 Toxoplasma gondii micronemal protein 1 TgMIC1 HMGL-like PF00682.19 KFH40994.1 - 0.047 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 HMGL-like SPC25 PF06703.11 KFH40995.1 - 1.1e-48 165.1 0.1 1.3e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SSXT PF05030.12 KFH40995.1 - 0.08 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) DUF3549 PF12069.8 KFH40995.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Arb1 PF09692.10 KFH40996.1 - 1.8e-113 379.7 0.0 2.1e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 HEAT PF02985.22 KFH40997.1 - 3.2e-15 54.9 11.9 0.0012 18.9 0.0 9.6 12 0 0 12 12 8 3 HEAT repeat HEAT_EZ PF13513.6 KFH40997.1 - 4.8e-10 39.7 10.5 8.8e-08 32.5 0.0 7.5 10 0 0 10 10 9 1 HEAT-like repeat HEAT_2 PF13646.6 KFH40997.1 - 1.8e-08 34.7 13.7 0.0058 17.0 0.3 6.8 5 2 2 7 7 7 4 HEAT repeats IBN_N PF03810.19 KFH40997.1 - 2.1e-08 34.0 8.5 2.8e-08 33.6 1.7 4.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KFH40997.1 - 5.6e-07 29.0 0.5 0.013 14.6 0.1 3.6 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal DRIM PF07539.12 KFH40997.1 - 7.2e-06 24.6 1.9 0.63 8.3 0.4 4.9 1 1 1 4 4 4 2 Down-regulated in metastasis CLASP_N PF12348.8 KFH40997.1 - 0.00022 20.9 3.8 1.2 8.7 0.2 5.2 3 3 3 6 6 6 1 CLASP N terminal DUF3385 PF11865.8 KFH40997.1 - 0.013 15.5 6.2 8.4 6.3 0.4 4.5 3 2 0 4 4 4 0 Domain of unknown function (DUF3385) Arm PF00514.23 KFH40997.1 - 0.018 15.1 5.5 9.1 6.5 0.0 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 KFH40997.1 - 0.04 14.5 2.6 50 4.6 0.0 6.0 6 1 0 7 7 7 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KFH40997.1 - 0.06 14.0 1.0 1.3e+02 3.7 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Cse1 PF08506.10 KFH40997.1 - 0.079 11.8 0.0 0.95 8.2 0.0 2.7 2 1 0 2 2 2 0 Cse1 NUC173 PF08161.12 KFH40997.1 - 0.46 10.1 5.7 14 5.3 0.0 4.6 5 2 0 5 5 5 0 NUC173 domain EMC3_TMCO1 PF01956.16 KFH40998.1 - 7.8e-54 181.9 0.7 1.1e-53 181.5 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Alg6_Alg8 PF03155.15 KFH40999.1 - 1.6e-125 419.9 29.7 1.1e-79 268.7 12.7 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MMS19_N PF14500.6 KFH41000.1 - 8.9e-53 179.5 0.0 1.7e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KFH41000.1 - 4.5e-18 65.6 0.2 2.2e-17 63.3 0.4 2.0 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal PUL PF08324.11 KFH41000.1 - 0.012 14.9 0.0 0.038 13.2 0.0 1.8 1 0 0 1 1 1 0 PUL domain Med17 PF10156.9 KFH41001.1 - 1.7e-90 303.9 0.0 2.1e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex BRO1 PF03097.18 KFH41002.1 - 5.7e-07 28.7 0.0 7.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Ribosomal_60s PF00428.19 KFH41003.1 - 1.6e-26 92.7 12.1 1.8e-26 92.5 12.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KFH41003.1 - 0.17 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Pmp3 PF01679.17 KFH41004.1 - 1.1e-19 70.3 8.7 1.5e-19 69.9 8.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ATP11 PF06644.11 KFH41005.1 - 5.8e-98 328.0 0.0 7.1e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein DUF3446 PF11928.8 KFH41006.1 - 0.28 11.5 6.2 1.7 9.0 2.2 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 KFH41006.1 - 2.5 7.6 26.8 0.067 12.8 13.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNA_pol_Rbc25 PF08292.12 KFH41007.1 - 2.4e-34 118.3 1.1 9.9e-34 116.4 1.1 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFH41007.1 - 2.2e-15 56.8 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pox_T4_N PF04491.12 KFH41007.1 - 0.54 10.2 3.7 8.7 6.3 3.7 2.3 1 1 0 1 1 1 0 Poxvirus T4 protein, N terminus SNF2_N PF00176.23 KFH41008.1 - 1.5e-61 208.0 0.6 2.9e-61 207.1 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41008.1 - 1.7e-15 57.3 0.1 4.9e-15 55.8 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KFH41008.1 - 7.5e-07 28.9 1.5 2.2e-06 27.4 1.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH41008.1 - 1.3e-06 28.2 3.7 4.1e-06 26.6 3.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFH41008.1 - 2.1e-06 27.9 0.1 2.1e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KFH41008.1 - 2.9e-06 27.0 1.6 2.9e-06 27.0 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH41008.1 - 9e-06 25.9 5.6 2.2e-05 24.7 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH41008.1 - 2.6e-05 24.1 2.5 2.6e-05 24.1 2.5 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH41008.1 - 0.00027 20.8 3.9 0.00068 19.5 3.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFH41008.1 - 0.00058 20.0 4.9 0.0039 17.3 5.2 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING AAA_34 PF13872.6 KFH41008.1 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 KFH41008.1 - 0.0052 16.0 2.4 0.006 15.8 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_4 PF14570.6 KFH41008.1 - 0.0084 15.9 2.4 0.04 13.7 2.7 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain DUF5094 PF17015.5 KFH41008.1 - 0.28 11.3 9.3 0.81 9.8 9.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) KfrA_N PF11740.8 KFH41008.1 - 0.28 11.9 4.1 0.42 11.3 1.8 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EIIBC-GUT_N PF03612.14 KFH41008.1 - 0.34 10.6 4.1 2.2 8.0 3.7 2.4 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Prok-RING_4 PF14447.6 KFH41008.1 - 0.86 9.5 12.0 9.1 6.2 12.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YL1 PF05764.13 KFH41008.1 - 2.9 7.9 29.3 0.11 12.7 16.1 2.7 2 0 0 2 2 2 0 YL1 nuclear protein DZR PF12773.7 KFH41008.1 - 6.7 6.8 5.8 16 5.7 5.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon HMGL-like PF00682.19 KFH41009.1 - 1.9e-70 237.4 0.0 3.1e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KFH41009.1 - 2.4e-22 79.3 0.0 5.6e-22 78.1 0.0 1.7 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain SPT2 PF08243.11 KFH41010.1 - 9.1e-12 45.5 23.8 1.3e-09 38.6 23.8 2.5 1 1 0 1 1 1 1 SPT2 chromatin protein WD40 PF00400.32 KFH41011.1 - 2.8e-14 53.2 6.0 6.9e-06 26.7 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41011.1 - 0.024 14.9 0.0 10 6.5 0.0 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_61 PF03443.14 KFH41012.1 - 2.1e-56 191.1 0.0 2.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HWE_HK PF07536.14 KFH41013.1 - 0.06 14.1 3.2 0.14 12.8 1.7 2.3 2 0 0 2 2 2 0 HWE histidine kinase Syntaxin-6_N PF09177.11 KFH41013.1 - 0.6 10.7 7.1 2.1 8.9 1.7 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 KFH41013.1 - 1.4 9.2 6.1 0.84 9.9 2.6 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KFH41013.1 - 5.4 5.8 15.3 0.31 9.9 3.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Cep57_CLD PF14073.6 KFH41013.1 - 7.8 6.5 16.7 0.27 11.3 5.2 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 DUF1664 PF07889.12 KFH41013.1 - 9.6 6.3 7.0 3.7 7.6 0.8 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) DUF1748 PF08520.10 KFH41014.1 - 1.5e-30 104.9 0.0 2.5e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FMO-like PF00743.19 KFH41015.1 - 6e-13 48.1 0.1 5.9e-11 41.5 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH41015.1 - 8.6e-12 45.1 0.0 2.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFH41015.1 - 1.7e-07 30.8 0.0 1.9e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH41015.1 - 5e-07 29.2 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH41015.1 - 9.6e-05 22.4 0.0 0.001 19.1 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFH41015.1 - 0.00073 18.8 0.0 0.84 8.7 0.0 3.0 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFH41015.1 - 0.0016 18.1 0.0 0.23 11.0 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH41015.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KFH41015.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ABC_membrane PF00664.23 KFH41016.1 - 6.7e-87 291.6 15.5 6.3e-45 154.0 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH41016.1 - 1.3e-60 203.8 0.0 4.4e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH41016.1 - 1.2e-16 60.8 0.5 3.1e-05 23.5 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFH41016.1 - 5.2e-11 42.9 0.0 0.38 10.5 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH41016.1 - 1.7e-08 34.1 0.6 0.0024 17.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH41016.1 - 3.4e-07 30.8 0.2 0.045 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFH41016.1 - 5.7e-06 26.7 1.0 0.17 12.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH41016.1 - 7e-06 26.0 0.2 0.17 11.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KFH41016.1 - 2.4e-05 24.2 0.0 0.23 11.1 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 KFH41016.1 - 8.7e-05 22.2 0.0 1.7 8.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KFH41016.1 - 0.00016 22.2 0.4 0.27 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KFH41016.1 - 0.00057 18.8 0.8 1.8 7.3 0.0 3.8 4 1 0 4 4 4 1 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 KFH41016.1 - 0.0022 18.1 0.0 0.86 9.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KFH41016.1 - 0.0023 17.7 0.0 2.2 8.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 KFH41016.1 - 0.0027 17.6 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 KFH41016.1 - 0.0048 17.1 1.5 1.1 9.6 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KFH41016.1 - 0.05 12.8 1.6 6.8 5.8 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 KFH41016.1 - 0.05 14.0 0.2 22 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 KFH41016.1 - 0.051 14.1 0.0 5.1 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KFH41016.1 - 0.087 11.8 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_33 PF13671.6 KFH41016.1 - 0.097 12.8 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFH41016.1 - 0.11 11.7 0.1 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KFH41016.1 - 0.23 10.8 0.5 11 5.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KFH41016.1 - 0.25 11.4 0.4 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 KFH41016.1 - 0.47 9.8 3.3 9.4 5.5 0.1 3.3 5 0 0 5 5 5 0 KaiC Zn_clus PF00172.18 KFH41017.1 - 2.6e-07 30.6 7.7 4.6e-07 29.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_synt_4 PF04669.13 KFH41018.1 - 5.3e-23 81.6 0.2 2.9e-21 75.9 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis Pkinase PF00069.25 KFH41019.1 - 3.8e-43 147.7 0.0 1.6e-42 145.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41019.1 - 2.7e-30 105.5 0.0 4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH41019.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFH41019.1 - 0.0038 16.6 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CTD PF12815.7 KFH41020.1 - 2.4e-27 95.3 75.0 2.5e-17 63.2 13.6 4.7 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 KFH41020.1 - 2.2e-23 81.9 0.1 3.7e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFH41020.1 - 6.6e-21 75.2 10.5 6.6e-21 75.2 10.5 2.5 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KFH41020.1 - 0.00048 20.0 22.1 0.0046 16.9 2.4 4.9 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KFH41020.1 - 0.066 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) Myosin_N PF02736.19 KFH41020.1 - 9.8 6.1 10.2 9.7 6.1 0.6 3.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain MFS_1 PF07690.16 KFH41021.1 - 2.8e-26 92.3 18.8 2.8e-26 92.3 18.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KFH41021.1 - 0.67 9.7 7.7 0.21 11.3 1.4 2.5 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 ADH_zinc_N PF00107.26 KFH41022.1 - 4.3e-31 107.6 0.1 3.7e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH41022.1 - 2.3e-15 57.8 0.0 3.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41022.1 - 6.2e-07 29.3 0.0 4.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFH41022.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Spt5_N PF11942.8 KFH41023.1 - 0.4 11.7 5.3 0.12 13.4 2.5 1.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SRP-alpha_N PF04086.13 KFH41023.1 - 1.9 8.3 8.3 2.5 7.9 8.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PK PF00224.21 KFH41024.1 - 3e-170 565.7 3.4 3.8e-170 565.4 3.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFH41024.1 - 5.7e-37 126.5 0.0 1.6e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFH41024.1 - 0.00011 21.4 0.4 0.00043 19.5 0.2 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KFH41024.1 - 0.038 13.0 0.1 0.66 8.9 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glyco_hydro_2_N PF02837.18 KFH41025.1 - 5.5e-14 52.4 0.5 8.1e-12 45.4 0.5 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFH41025.1 - 2.5e-09 37.8 0.2 1.1e-08 35.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFH41025.1 - 1.8e-06 27.3 0.0 1.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 KFH41025.1 - 0.016 15.7 0.0 0.048 14.2 0.0 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain MFS_1 PF07690.16 KFH41026.1 - 2.7e-48 164.7 31.4 2.7e-48 164.7 31.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41026.1 - 6.5e-11 41.8 2.2 6.5e-11 41.8 2.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KFH41026.1 - 2.5e-08 33.6 6.1 2.5e-08 33.6 6.1 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFH41026.1 - 3.7e-06 25.6 0.8 5.7e-06 25.0 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1158 PF06643.11 KFH41026.1 - 0.016 15.7 0.0 0.048 14.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) ABM PF03992.16 KFH41028.1 - 2.5e-13 50.0 0.0 2.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AMP_N PF05195.16 KFH41028.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain HeLo PF14479.6 KFH41029.1 - 6.7e-06 26.1 0.5 0.047 13.5 0.1 2.3 1 1 0 2 2 2 2 Prion-inhibition and propagation TENA_THI-4 PF03070.16 KFH41030.1 - 0.018 14.9 0.0 0.079 12.8 0.0 1.8 2 0 0 2 2 2 0 TENA/THI-4/PQQC family AtuA PF07287.11 KFH41031.1 - 1.6e-129 431.7 0.0 1.9e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CMD PF02627.20 KFH41032.1 - 0.00087 19.3 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family AA_permease_2 PF13520.6 KFH41033.1 - 4.8e-75 253.0 39.4 5.9e-75 252.7 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH41033.1 - 9.3e-17 60.8 30.6 1.2e-16 60.4 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease SUR7 PF06687.12 KFH41034.1 - 0.031 13.9 0.4 0.031 13.9 0.4 1.8 2 0 0 2 2 2 0 SUR7/PalI family FAA_hydrolase PF01557.18 KFH41035.1 - 9.7e-57 192.1 0.0 1.3e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFH41035.1 - 1.1e-32 112.4 0.0 1.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal NFACT-R_1 PF05670.13 KFH41036.1 - 4e-33 114.3 0.5 3e-20 72.9 0.0 3.4 1 1 1 2 2 2 2 NFACT protein RNA binding domain DUF4337 PF14235.6 KFH41036.1 - 7.2 6.7 7.8 11 6.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Flavokinase PF01687.17 KFH41037.1 - 3.2e-09 37.1 0.0 5.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Sugar_tr PF00083.24 KFH41038.1 - 6.7e-87 292.2 18.6 7.9e-87 292.0 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41038.1 - 3.3e-16 59.2 41.8 1.5e-11 43.9 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 KFH41039.1 - 7.2e-66 222.1 3.2 8.5e-66 221.9 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH41039.1 - 2.5e-48 164.1 1.9 3e-48 163.9 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH41039.1 - 3.8e-09 36.7 1.3 5.9e-09 36.1 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH41039.1 - 0.0033 16.9 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFH41039.1 - 0.044 13.7 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFH41039.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3425 PF11905.8 KFH41040.1 - 8.2e-15 54.9 0.7 1.5e-14 54.0 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFH41040.1 - 3.2e-05 24.0 5.0 0.019 15.0 2.0 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KFH41040.1 - 0.0093 16.0 0.2 0.0093 16.0 0.2 2.4 1 1 1 2 2 2 1 Basic region leucine zipper ScsC_N PF18312.1 KFH41040.1 - 0.048 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain YabA PF06156.13 KFH41040.1 - 0.057 14.1 0.0 0.15 12.7 0.0 1.6 2 0 0 2 2 1 0 Initiation control protein YabA CCDC144C PF14915.6 KFH41040.1 - 0.089 11.9 0.9 0.13 11.4 0.9 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 KFH41040.1 - 0.14 11.0 0.6 0.21 10.5 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3138 PF11336.8 KFH41040.1 - 0.18 10.4 1.1 0.26 9.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Nnf1 PF03980.14 KFH41040.1 - 0.3 11.5 4.1 0.64 10.4 4.1 1.5 1 0 0 1 1 1 0 Nnf1 ADIP PF11559.8 KFH41040.1 - 1.2 9.2 6.2 2.3 8.3 6.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mito_fiss_reg PF05308.11 KFH41040.1 - 2.9 7.9 10.5 37 4.3 0.0 2.5 1 1 1 3 3 3 0 Mitochondrial fission regulator CBM_21 PF03370.13 KFH41041.1 - 2.7e-35 121.0 0.1 4.3e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFH41041.1 - 1.4e-09 38.4 0.1 2.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AA_permease_2 PF13520.6 KFH41042.1 - 9e-42 143.4 32.6 1.2e-41 143.0 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH41042.1 - 1.2e-20 73.6 31.3 1.7e-20 73.1 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease CTV_P6 PF06706.11 KFH41042.1 - 0.048 13.4 1.6 0.75 9.6 0.0 3.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein GAPT PF11770.8 KFH41042.1 - 0.083 12.8 0.8 0.2 11.5 0.8 1.7 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) GST_N_2 PF13409.6 KFH41043.1 - 5.9e-08 32.9 0.0 8.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFH41043.1 - 8.5e-07 29.3 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFH41043.1 - 2.2e-06 27.9 0.0 4.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFH41043.1 - 4.6e-05 23.5 0.0 7.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH41043.1 - 0.0043 17.2 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH41043.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M24 PF00557.24 KFH41044.1 - 4.9e-57 193.0 0.0 6.5e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFH41044.1 - 1.5e-25 89.3 0.0 2.7e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain UCH PF00443.29 KFH41045.1 - 4.6e-36 124.6 0.0 6.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFH41045.1 - 1.3e-24 85.7 0.7 7.8e-23 80.0 0.0 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KFH41045.1 - 2.3e-23 82.3 11.5 4.3e-19 68.6 2.7 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KFH41045.1 - 2.9e-19 68.6 0.0 3.2e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KFH41045.1 - 8.4e-18 65.0 0.0 3.5e-16 59.7 0.0 3.1 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase RPE65 PF03055.15 KFH41046.1 - 1.6e-116 390.2 0.0 1.9e-116 390.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Patatin PF01734.22 KFH41047.1 - 9.3e-15 55.3 0.0 2.1e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase TBX PF12598.8 KFH41048.1 - 0.57 11.0 2.3 1.1 10.1 2.3 1.4 1 0 0 1 1 1 0 T-box transcription factor FTA4 PF13093.6 KFH41049.1 - 4.5e-49 167.1 0.5 6e-49 166.7 0.5 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Seryl_tRNA_N PF02403.22 KFH41049.1 - 0.095 12.9 1.3 0.28 11.4 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cullin PF00888.22 KFH41049.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Cullin family ABC2_membrane PF01061.24 KFH41050.1 - 4e-38 131.0 18.6 7.6e-38 130.0 18.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFH41050.1 - 4.7e-25 88.7 0.0 8.7e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFH41050.1 - 6e-05 23.0 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH41050.1 - 0.0057 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH41050.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KFH41050.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFH41050.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KFH41050.1 - 0.042 14.4 0.0 0.087 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KFH41050.1 - 0.066 13.1 0.1 0.31 11.0 0.1 2.1 1 0 0 1 1 1 0 CDR ABC transporter AAA_22 PF13401.6 KFH41050.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFH41050.1 - 0.11 12.9 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH41050.1 - 0.14 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFH41050.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 KFH41050.1 - 0.24 11.5 22.7 0.095 12.9 3.0 3.5 3 0 0 3 3 3 0 Laminin EGF domain ABC2_membrane_3 PF12698.7 KFH41050.1 - 0.28 10.2 28.6 0.014 14.5 21.9 2.0 2 1 1 3 3 3 0 ABC-2 family transporter protein EGF PF00008.27 KFH41050.1 - 0.68 10.3 14.8 0.66 10.3 0.2 3.9 3 0 0 3 3 3 0 EGF-like domain Aa_trans PF01490.18 KFH41051.1 - 2.9e-74 250.2 21.9 3.5e-74 249.9 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NGP1NT PF08153.12 KFH41053.1 - 3.7e-52 175.9 0.6 6.9e-52 175.0 0.6 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFH41053.1 - 2.1e-16 60.0 0.0 2e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFH41053.1 - 4.3e-05 23.6 0.7 0.051 13.6 0.1 3.4 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KFH41053.1 - 5.5e-05 22.7 0.1 0.00032 20.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFH41053.1 - 0.00065 19.3 0.0 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH41053.1 - 0.00066 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFH41053.1 - 0.0051 16.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KFH41053.1 - 0.058 13.6 0.1 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HORMA PF02301.18 KFH41054.1 - 1.9e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFH41054.1 - 0.0015 18.6 0.3 0.0066 16.5 0.3 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF2660 PF10859.8 KFH41054.1 - 0.011 16.2 0.1 0.025 15.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) NifU_N PF01592.16 KFH41055.1 - 2.2e-54 183.0 0.1 3e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain bMG5 PF17972.1 KFH41055.1 - 0.054 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain DUF4185 PF13810.6 KFH41056.1 - 3.4e-07 29.8 2.8 3.4e-07 29.8 2.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) p450 PF00067.22 KFH41057.1 - 9.3e-73 245.5 0.0 1.2e-72 245.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KFH41057.1 - 0.03 14.1 0.9 0.081 12.7 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) adh_short_C2 PF13561.6 KFH41058.1 - 4.1e-50 170.5 0.0 5.2e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH41058.1 - 5.2e-41 140.3 0.0 7.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH41058.1 - 1.2e-10 41.6 0.0 1.8e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH41058.1 - 0.00043 19.8 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH41058.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 7tm_2 PF00002.24 KFH41061.1 - 2.2e-05 23.9 10.0 2.2e-05 23.9 10.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFH41061.1 - 0.052 12.7 5.6 0.023 13.8 2.8 1.7 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor TauD PF02668.16 KFH41062.1 - 1.3e-26 94.0 0.2 1.8e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFH41062.1 - 0.14 11.3 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 CsiD Cellulase PF00150.18 KFH41063.1 - 8e-32 110.8 0.1 9.8e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP1_TM PF14812.6 KFH41063.1 - 0.0061 16.9 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FolB PF02152.18 KFH41065.1 - 3.4e-22 79.1 0.0 3e-17 63.2 0.0 2.3 2 1 0 2 2 2 2 Dihydroneopterin aldolase IMS_C PF11799.8 KFH41065.1 - 0.16 12.7 0.0 0.53 11.0 0.0 2.0 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain Abhydrolase_3 PF07859.13 KFH41066.1 - 1.1e-19 71.2 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KFH41066.1 - 3.1e-08 32.7 0.0 0.0038 15.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFH41066.1 - 1.8e-07 30.9 0.0 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFH41066.1 - 1.2e-05 24.4 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KFH41066.1 - 2.9e-05 23.1 0.0 7.5e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KFH41066.1 - 0.00019 20.8 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KFH41066.1 - 0.0022 17.7 0.1 0.0085 15.8 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KFH41066.1 - 0.035 13.6 0.1 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase F-box-like PF12937.7 KFH41068.1 - 0.0016 18.3 0.1 0.0016 18.3 0.1 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KFH41068.1 - 0.0044 16.9 1.0 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 KFH41068.1 - 0.097 12.6 0.8 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 F-box Ammonium_transp PF00909.21 KFH41069.1 - 3.4e-111 371.8 32.8 3.9e-111 371.6 32.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Zn_clus PF00172.18 KFH41070.1 - 0.0058 16.7 6.8 0.012 15.7 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BBIP10 PF14777.6 KFH41070.1 - 0.077 12.6 0.1 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 CRT10 PF08728.10 KFH41071.1 - 6.9e-12 44.4 0.0 3.1e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 CRT10 BUD22 PF09073.10 KFH41071.1 - 0.43 9.9 6.4 0.8 9.0 6.4 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KFH41071.1 - 0.61 9.5 11.0 0.97 8.8 11.0 1.2 1 0 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 KFH41071.1 - 3 7.3 5.2 5.4 6.4 5.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Roughex PF06020.11 KFH41071.1 - 5.9 5.9 9.4 10 5.1 9.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 KFH41071.1 - 7.9 4.6 11.7 12 4.0 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Caskin-Pro-rich PF16907.5 KFH41073.1 - 0.058 13.9 0.9 0.058 13.9 0.9 2.1 1 1 1 2 2 2 0 Proline rich region of Caskin proteins DUF3605 PF12239.8 KFH41074.1 - 8.2e-51 172.4 0.9 2.3e-50 170.9 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 KFH41075.1 - 9.5e-15 54.1 0.0 8e-09 34.6 0.0 2.1 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase His_Phos_2 PF00328.22 KFH41076.1 - 4.9e-45 154.5 0.0 5.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hydantoinase_B PF02538.14 KFH41077.1 - 2.1e-217 722.6 0.1 3.1e-217 722.1 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFH41077.1 - 2.7e-104 348.5 0.6 5.4e-104 347.5 0.6 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFH41077.1 - 5.6e-61 205.3 0.9 2.8e-59 199.8 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF4928 PF16280.5 KFH41077.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) Aconitase PF00330.20 KFH41078.1 - 9.5e-146 486.4 0.0 1.2e-145 486.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFH41078.1 - 1.6e-38 132.0 0.0 2.9e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KFH41078.1 - 0.0044 15.8 0.1 0.0094 14.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF521) Pyridoxal_deC PF00282.19 KFH41079.1 - 7.5e-24 84.1 0.0 9.7e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFH41079.1 - 4.8e-05 22.8 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GvpO PF05800.11 KFH41079.1 - 0.064 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Aminotran_1_2 PF00155.21 KFH41079.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Aminotran_5 PF00266.19 KFH41079.1 - 0.11 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V UAF_Rrn10 PF05234.11 KFH41080.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 UAF complex subunit Rrn10 APG5 PF04106.12 KFH41081.1 - 2e-46 158.5 0.0 7.1e-46 156.6 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 MARVEL PF01284.23 KFH41082.1 - 1.9e-15 57.2 13.2 2.3e-15 56.9 13.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srx PF10328.9 KFH41082.1 - 0.0081 15.8 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 KFH41082.1 - 0.98 8.1 2.4 1.2 7.8 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NmrA PF05368.13 KFH41083.1 - 4.4e-07 29.7 0.2 6.6e-06 25.8 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KFH41083.1 - 2.9e-06 27.3 0.0 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KFH41083.1 - 0.0023 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFH41083.1 - 0.0044 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ribosomal_60s PF00428.19 KFH41083.1 - 0.054 14.1 2.5 0.096 13.3 2.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein F420_oxidored PF03807.17 KFH41083.1 - 0.061 13.9 0.0 0.68 10.6 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KFH41083.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LpxI_N PF17930.1 KFH41083.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 LpxI N-terminal domain Nucleopor_Nup85 PF07575.13 KFH41084.1 - 4.6e-19 68.4 0.0 1.8e-11 43.4 0.0 2.6 2 1 0 2 2 2 2 Nup85 Nucleoporin SDA1 PF05285.12 KFH41084.1 - 0.94 8.8 14.0 1.8 7.9 14.0 1.4 1 0 0 1 1 1 0 SDA1 ADH_N PF08240.12 KFH41085.1 - 7.1e-21 74.1 1.9 2.5e-20 72.4 1.9 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH41085.1 - 7.9e-20 71.2 0.2 1.5e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFH41085.1 - 0.0065 15.8 0.8 0.012 15.0 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH41085.1 - 0.012 16.7 0.0 0.024 15.7 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH41085.1 - 0.012 15.1 0.1 0.044 13.3 0.1 1.8 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KFH41085.1 - 0.023 15.0 0.1 0.047 13.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KFH41085.1 - 0.04 13.5 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-AN1 PF01428.16 KFH41086.1 - 1.3e-13 50.9 5.4 1.3e-13 50.9 5.4 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger HhH-GPD PF00730.25 KFH41087.1 - 5.9e-19 68.5 0.0 1.2e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFH41087.1 - 1.8e-08 33.8 0.0 4.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif UPF0561 PF10573.9 KFH41087.1 - 0.096 12.8 2.3 0.22 11.7 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 HHH_5 PF14520.6 KFH41087.1 - 0.14 12.8 0.0 0.51 11.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2462 PF09495.10 KFH41089.1 - 9.7e-12 45.5 11.5 1.4e-11 44.9 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) WD40 PF00400.32 KFH41090.1 - 3.4e-20 72.0 17.2 8.3e-05 23.3 1.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41090.1 - 1.4e-11 44.5 0.5 0.0056 17.0 0.0 5.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH41090.1 - 0.009 14.7 0.1 1.5 7.4 0.0 3.1 3 0 0 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.11 KFH41090.1 - 0.011 15.6 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KFH41090.1 - 0.067 13.1 0.0 8.7 6.5 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat Acyl-CoA_dh_1 PF00441.24 KFH41092.1 - 8.5e-14 52.0 0.0 6.5e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH41092.1 - 2.1e-12 47.0 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 KFH41092.1 - 3.9e-11 43.1 0.0 9e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH41092.1 - 0.00058 20.1 0.5 0.01 16.1 0.0 2.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain A_deaminase PF00962.22 KFH41093.1 - 7.8e-22 78.0 0.0 3.4e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase Pkinase PF00069.25 KFH41094.1 - 2.4e-11 43.5 0.0 5.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KFH41094.1 - 5e-09 35.6 1.3 0.1 12.9 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.17 KFH41094.1 - 5.4e-07 29.2 0.0 9.6e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KFH41094.1 - 1e-06 28.9 0.1 6.3e-06 26.3 0.0 2.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFH41094.1 - 1.3e-05 25.5 0.4 0.14 12.7 0.2 3.7 3 1 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KFH41094.1 - 2.9e-05 24.4 0.3 0.0044 17.4 0.1 2.8 2 1 1 3 3 3 2 HEAT repeats Kinase-like PF14531.6 KFH41094.1 - 0.019 14.3 0.0 0.048 13.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Vac14_Fab1_bd PF12755.7 KFH41094.1 - 0.12 13.0 0.1 4.1 8.1 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFH41094.1 - 0.12 10.9 0.0 1.8 7.0 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region Hist_deacetyl PF00850.19 KFH41096.1 - 1e-77 261.6 0.0 1.7e-77 260.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain URO-D PF01208.17 KFH41097.1 - 4.8e-126 420.6 0.0 5.4e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) GTP_EFTU PF00009.27 KFH41098.1 - 1.4e-08 34.5 0.0 4.7e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain WD40 PF00400.32 KFH41099.1 - 5.5e-12 46.0 2.4 0.33 11.9 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41099.1 - 0.0067 16.7 0.1 4.7 7.6 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HA2 PF04408.23 KFH41100.1 - 1.3e-19 70.4 0.3 5.4e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH41100.1 - 1.3e-12 48.0 0.0 3.8e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFH41100.1 - 1.1e-10 41.7 0.0 2.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFH41100.1 - 2.1e-05 24.3 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFH41100.1 - 0.00044 20.5 0.0 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFH41100.1 - 0.016 15.7 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KFH41100.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KFH41100.1 - 0.02 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFH41100.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH41100.1 - 0.14 12.6 0.0 0.51 10.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFH41100.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Velvet PF11754.8 KFH41101.1 - 1e-47 163.2 0.0 2.4e-47 162.0 0.0 1.5 1 1 0 1 1 1 1 Velvet factor FOLN PF09289.10 KFH41102.1 - 0.0044 17.2 2.4 0.0055 16.9 0.4 2.3 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Ion_trans PF00520.31 KFH41104.1 - 3.6e-123 409.5 81.5 2.2e-44 151.5 6.7 4.9 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFH41104.1 - 0.0033 16.1 1.2 0.0033 16.1 1.2 7.5 6 1 1 7 7 7 6 Polycystin cation channel Staph_haemo PF05480.11 KFH41104.1 - 0.026 14.3 0.2 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein HMG_box PF00505.19 KFH41105.1 - 0.0012 19.2 0.1 0.0025 18.2 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MutS_V PF00488.21 KFH41106.1 - 1.4e-47 162.1 0.0 3.8e-47 160.8 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KFH41106.1 - 8.7e-09 35.9 0.0 3.2e-08 34.0 0.0 1.9 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KFH41106.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 MutS family domain IV HisG PF01634.18 KFH41107.1 - 7.8e-55 185.2 0.0 1.1e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KFH41107.1 - 8.1e-28 96.4 0.1 1.7e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain DUF3837 PF12939.7 KFH41107.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF3602 PF12223.8 KFH41109.1 - 3.5e-15 56.4 9.6 8.3e-12 45.5 1.0 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Rab5ip PF07019.12 KFH41110.1 - 6e-28 97.3 7.7 7.2e-28 97.0 7.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RL11D PF11088.8 KFH41110.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 V-SNARE_C PF12352.8 KFH41111.1 - 0.093 13.0 5.5 0.042 14.1 2.5 1.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Complex1_LYR_2 PF13233.6 KFH41114.1 - 1.2e-20 74.0 0.1 1.5e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFH41114.1 - 2.5e-11 43.5 0.0 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ING PF12998.7 KFH41115.1 - 2e-24 86.1 3.5 3.2e-24 85.4 3.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1704 PF08014.11 KFH41115.1 - 0.046 12.7 1.0 0.053 12.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1704) DUF765 PF05570.11 KFH41115.1 - 0.16 12.2 0.4 0.16 12.2 0.4 3.5 3 0 0 3 3 3 0 Circovirus protein of unknown function (DUF765) PHD PF00628.29 KFH41116.1 - 9.7e-09 35.0 8.3 1.9e-08 34.1 8.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFH41116.1 - 0.0016 18.0 4.0 0.0028 17.2 4.0 1.4 1 0 0 1 1 1 1 PHD-finger MMgT PF10270.9 KFH41117.1 - 7.3e-34 116.1 0.0 8.6e-34 115.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter ABC_tran PF00005.27 KFH41119.1 - 4.2e-49 166.6 0.2 1.3e-25 90.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFH41119.1 - 2.5e-22 79.5 42.4 6.6e-14 51.8 15.8 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFH41119.1 - 6.2e-21 75.5 4.3 0.0001 22.3 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH41119.1 - 2.8e-10 39.8 1.4 0.00017 21.3 0.2 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFH41119.1 - 4e-09 36.2 1.4 0.085 12.3 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH41119.1 - 1.9e-05 25.3 7.8 0.0088 16.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KFH41119.1 - 0.00017 21.6 1.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFH41119.1 - 0.00023 21.6 0.1 1.3 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KFH41119.1 - 0.00064 19.5 0.1 0.47 10.1 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KFH41119.1 - 0.00092 19.8 0.2 0.59 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_27 PF13514.6 KFH41119.1 - 0.0013 18.3 0.3 0.57 9.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFH41119.1 - 0.0019 18.0 0.6 1.8 8.2 0.3 2.7 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 KFH41119.1 - 0.0019 18.9 0.0 0.13 13.0 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 KFH41119.1 - 0.012 14.9 0.6 3.5 6.9 0.2 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 KFH41119.1 - 0.027 14.7 0.1 6.4 7.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KFH41119.1 - 0.046 13.5 0.3 7.7 6.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 KFH41119.1 - 0.058 13.0 1.2 6.1 6.4 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 KFH41119.1 - 0.073 12.0 1.4 0.32 9.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KFH41119.1 - 0.091 13.0 0.9 4.9 7.4 0.5 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFH41119.1 - 0.15 11.8 0.0 31 4.3 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 KFH41119.1 - 0.56 10.3 2.8 19 5.3 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_25 PF13481.6 KFH41119.1 - 1.8 8.1 3.9 26 4.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain UCH_1 PF13423.6 KFH41120.1 - 1.3e-96 324.0 0.2 2.5e-96 323.1 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KFH41120.1 - 3e-24 86.4 0.0 3.7e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KFH41120.1 - 1.8e-05 24.4 0.1 3.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ac81 PF05820.11 KFH41120.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 FlaG PF03646.15 KFH41120.1 - 0.1 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 FlaG protein Zn_clus PF00172.18 KFH41121.1 - 1.6e-09 37.8 11.1 2.6e-09 37.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41121.1 - 1.4e-05 24.3 0.0 3.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 KFH41121.1 - 0.055 13.5 12.1 0.12 12.4 12.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_25 PF13649.6 KFH41122.1 - 3.2e-08 34.2 0.0 5.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH41122.1 - 9.3e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH41122.1 - 3e-05 24.6 0.0 5.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41122.1 - 0.00055 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain P53_TAD PF08563.11 KFH41122.1 - 0.012 15.0 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 P53 transactivation motif PEPCK_ATP PF01293.20 KFH41123.1 - 1.7e-214 712.8 0.0 2e-214 712.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KFH41123.1 - 0.063 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFH41123.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ran-binding PF05508.11 KFH41124.1 - 1.9e-101 339.1 0.0 2.9e-101 338.6 0.0 1.3 1 0 0 1 1 1 1 RanGTP-binding protein PHY PF00360.20 KFH41125.1 - 8.9e-28 96.8 0.0 1.9e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 KFH41125.1 - 3.6e-18 65.8 0.0 2.2e-17 63.2 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KFH41125.1 - 2e-15 57.3 0.1 4.8e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KFH41125.1 - 7.2e-13 49.3 0.0 2e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KFH41125.1 - 1.5e-11 44.1 2.5 2e-11 43.7 0.8 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KFH41125.1 - 3.9e-08 33.9 0.0 1e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KFH41125.1 - 0.027 14.3 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cupin_8 PF13621.6 KFH41126.1 - 2.8e-25 89.5 0.0 3.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFH41126.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KFH41126.1 - 0.019 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 KFH41126.1 - 0.042 14.3 0.0 0.36 11.3 0.0 2.3 2 1 0 2 2 2 0 JmjC domain, hydroxylase CK_II_beta PF01214.18 KFH41127.1 - 7.6e-74 247.5 0.0 1.2e-73 246.8 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit CENP-B_dimeris PF09026.10 KFH41127.1 - 0.75 10.2 9.2 1.6 9.1 5.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spt5_N PF11942.8 KFH41127.1 - 0.76 10.8 9.7 0.68 11.0 3.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 KFH41127.1 - 1 9.8 8.7 2.8 8.4 1.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 KFH41127.1 - 1.7 8.6 4.6 6.9 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4611 PF15387.6 KFH41127.1 - 3 8.1 8.1 4.5 7.6 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 KFH41127.1 - 4.6 6.9 5.1 4.7 6.9 1.4 2.1 2 0 0 2 2 2 0 FAM176 family Importin_rep_4 PF18808.1 KFH41127.1 - 5.8 7.3 7.1 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Importin repeat Copper-fist PF00649.18 KFH41128.1 - 2e-22 78.4 2.6 2e-22 78.4 2.6 3.1 1 1 3 4 4 4 1 Copper fist DNA binding domain GTP_EFTU PF00009.27 KFH41130.1 - 2e-42 144.9 0.0 3.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFH41130.1 - 8.2e-29 100.2 0.1 2.1e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFH41130.1 - 2.6e-09 37.3 0.8 6.6e-09 36.0 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH41130.1 - 0.0012 19.0 0.1 0.0067 16.5 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2780 PF11075.8 KFH41130.1 - 0.092 12.9 0.3 0.092 12.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) TFIIA PF03153.13 KFH41130.1 - 1.4 8.8 13.5 2.4 8.0 13.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 KFH41131.1 - 3.4e-68 225.6 1.3 3.2e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KFH41131.1 - 0.046 14.1 4.8 0.038 14.4 1.9 2.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family PNP_UDP_1 PF01048.20 KFH41132.1 - 1.4e-38 132.5 0.1 1.6e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DHBP_synthase PF00926.19 KFH41133.1 - 2.6e-76 255.5 0.0 3e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase H2TH PF06831.14 KFH41134.1 - 4.2e-21 74.7 0.0 7.8e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFH41134.1 - 1.6e-10 41.6 0.1 3.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 KFH41134.1 - 0.008 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Fungal_trans_2 PF11951.8 KFH41135.1 - 1e-23 83.8 0.2 1.4e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain LIME1 PF15332.6 KFH41135.1 - 4.2 6.9 5.9 0.4 10.2 1.2 1.6 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 DAO PF01266.24 KFH41136.1 - 2.7e-29 102.9 0.0 4e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH41136.1 - 2.5e-08 33.5 0.1 0.0075 15.5 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH41136.1 - 2.5e-05 24.4 0.0 8.5e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFH41136.1 - 6.7e-05 22.9 0.1 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KFH41136.1 - 0.00043 19.5 0.3 0.51 9.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFH41136.1 - 0.00051 19.0 0.2 0.59 8.9 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KFH41136.1 - 0.00059 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH41136.1 - 0.0039 16.5 0.1 0.0059 15.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFH41136.1 - 0.0048 16.0 5.2 0.76 8.8 2.2 2.2 1 1 1 2 2 2 2 FAD binding domain Sacchrp_dh_NADP PF03435.18 KFH41136.1 - 0.018 15.3 0.0 0.26 11.6 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFH41136.1 - 0.034 13.8 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KFH41136.1 - 0.049 13.0 0.2 0.15 11.4 0.2 1.7 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.18 KFH41136.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KFH41136.1 - 0.05 13.5 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 KFH41136.1 - 0.051 13.0 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.17 KFH41136.1 - 0.078 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KFH41136.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KFH41136.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KFH41136.1 - 0.15 11.3 0.1 0.53 9.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFH41136.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Nse PF11789.8 KFH41137.1 - 5.7e-22 77.3 0.6 5.7e-22 77.3 0.6 1.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFH41137.1 - 0.00062 19.5 0.5 0.0013 18.4 0.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 KFH41137.1 - 0.0011 19.0 0.3 0.0023 17.9 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFH41137.1 - 0.0011 18.8 0.3 0.002 18.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LUC7 PF03194.15 KFH41137.1 - 0.071 12.8 3.1 0.094 12.4 0.4 2.0 2 0 0 2 2 2 0 LUC7 N_terminus zf-ANAPC11 PF12861.7 KFH41137.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Nup54 PF13874.6 KFH41137.1 - 0.2 11.8 3.0 1.4 9.0 3.0 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Zn-ribbon_8 PF09723.10 KFH41137.1 - 1.5 9.0 4.0 0.4 10.8 0.4 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Methyltransf_33 PF10017.9 KFH41138.1 - 1e-82 277.8 0.0 1.2e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_12 PF08242.12 KFH41138.1 - 0.018 15.7 0.0 0.037 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFH41139.1 - 1.8e-18 66.9 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH41139.1 - 1.5e-17 64.0 0.0 2.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41139.1 - 2.3e-15 57.1 0.0 4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH41139.1 - 1e-14 54.6 0.0 1.4e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41139.1 - 2.5e-14 53.8 0.0 3.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFH41139.1 - 7e-05 22.4 0.0 8.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFH41139.1 - 0.00019 20.9 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFH41139.1 - 0.00021 20.7 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFH41139.1 - 0.00097 18.2 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 KFH41139.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KFH41139.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KFH41139.1 - 0.033 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KFH41139.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KFH41139.1 - 0.24 10.4 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Atx10homo_assoc PF09759.9 KFH41140.1 - 4.6e-11 42.6 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Fapy_DNA_glyco PF01149.24 KFH41141.1 - 3.3e-10 40.6 0.0 3.9e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain PAS_9 PF13426.7 KFH41142.1 - 1.4e-12 47.7 0.0 2.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFH41142.1 - 0.0044 17.3 0.1 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold zf-C2H2 PF00096.26 KFH41143.1 - 0.096 13.2 1.0 0.096 13.2 1.0 3.4 4 1 0 4 4 4 0 Zinc finger, C2H2 type Ribosomal_L14 PF00238.19 KFH41145.1 - 2e-45 153.8 2.4 2.4e-45 153.6 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.16 KFH41145.1 - 0.057 13.0 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar L-ring protein PI-PLC-C1 PF16670.5 KFH41146.1 - 1.7e-121 405.3 0.0 1.9e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent RGS PF00615.19 KFH41147.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain Phytase PF02333.15 KFH41148.1 - 6.4e-67 226.1 2.1 7.9e-64 216.0 0.1 2.6 2 1 1 3 3 3 2 Phytase EGF_2 PF07974.13 KFH41148.1 - 0.0019 18.5 16.9 0.0019 18.5 16.9 2.6 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFH41148.1 - 4.9 7.9 16.1 0.15 12.7 9.1 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF TFIIS_C PF01096.18 KFH41149.1 - 7.8e-16 57.6 4.2 7.8e-16 57.6 4.2 3.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFH41149.1 - 3.1e-11 43.0 2.4 3.1e-11 43.0 2.4 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 KFH41149.1 - 0.07 13.1 1.0 0.07 13.1 1.0 3.9 4 0 0 4 4 4 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 KFH41149.1 - 0.073 13.0 0.8 0.073 13.0 0.8 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_10 PF10058.9 KFH41149.1 - 6.9 6.5 19.5 1.7 8.4 1.6 3.8 2 2 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Lar_restr_allev PF14354.6 KFH41149.1 - 7.4 7.0 17.5 0.14 12.6 2.6 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar LrgB PF04172.16 KFH41150.1 - 1e-21 77.5 12.0 9.1e-15 54.8 2.4 2.5 2 0 0 2 2 2 2 LrgB-like family Arylesterase PF01731.20 KFH41150.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Arylesterase CCDC53 PF10152.9 KFH41151.1 - 0.11 12.9 0.7 0.16 12.3 0.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_M28 PF04389.17 KFH41153.1 - 4.9e-40 137.4 0.0 6.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH41153.1 - 3e-09 36.8 0.0 6.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFH41153.1 - 0.0011 18.7 0.0 0.0045 16.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 HpcH_HpaI PF03328.14 KFH41154.1 - 1.7e-36 125.4 0.0 2e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FMN_dh PF01070.18 KFH41155.1 - 1.1e-102 343.7 1.3 5e-98 328.3 0.1 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFH41155.1 - 2e-17 63.1 0.0 4.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFH41155.1 - 0.0012 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFH41155.1 - 0.009 15.0 0.1 0.094 11.7 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Fungal_trans PF04082.18 KFH41156.1 - 0.026 13.6 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41156.1 - 0.97 9.6 9.0 0.3 11.3 5.6 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.28 KFH41157.1 - 1e-09 39.0 0.1 2.3e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 SET domain Tmemb_55A PF09788.9 KFH41157.1 - 0.002 17.3 0.1 0.002 17.3 0.1 1.8 2 0 0 2 2 2 1 Transmembrane protein 55A Glyco_hydro_43 PF04616.14 KFH41158.1 - 6.8e-73 245.5 1.1 8.8e-73 245.1 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFH41158.1 - 8.2e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Rotamase PF00639.21 KFH41159.1 - 3.2e-22 79.3 0.0 4.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFH41159.1 - 1.4e-15 57.8 0.0 2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KFH41159.1 - 4e-07 30.0 0.7 4e-07 30.0 0.7 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KFH41159.1 - 6.4e-05 23.8 0.0 8.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.23 KFH41159.1 - 0.03 14.2 0.2 0.089 12.7 0.0 1.7 1 1 0 2 2 2 0 MAM domain, meprin/A5/mu WW_1 PF18507.1 KFH41159.1 - 0.12 12.1 0.8 0.2 11.4 0.8 1.4 1 0 0 1 1 1 0 WW domain HAUS-augmin3 PF14932.6 KFH41160.1 - 1.5e-05 24.8 5.4 0.00011 21.9 0.4 2.8 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 3 STAT_alpha PF01017.20 KFH41160.1 - 0.029 14.3 4.1 0.23 11.4 0.3 2.9 3 0 0 3 3 3 0 STAT protein, all-alpha domain DUF5033 PF16436.5 KFH41160.1 - 0.075 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) MCC-bdg_PDZ PF10506.9 KFH41160.1 - 0.088 12.8 0.4 0.088 12.8 0.4 3.4 5 1 0 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4298 PF14131.6 KFH41160.1 - 0.089 12.8 0.5 8.3 6.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF1840 PF08895.11 KFH41160.1 - 0.49 10.7 5.7 0.48 10.8 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Tektin PF03148.14 KFH41160.1 - 0.56 8.9 12.0 0.88 8.3 3.2 3.7 3 1 1 4 4 4 0 Tektin family FliJ PF02050.16 KFH41160.1 - 1.2 9.4 11.8 0.31 11.3 4.9 3.3 3 1 0 3 3 3 0 Flagellar FliJ protein Synaptobrevin PF00957.21 KFH41160.1 - 1.8 8.4 3.6 13 5.7 2.1 2.9 2 1 1 3 3 3 0 Synaptobrevin BLOC1_2 PF10046.9 KFH41160.1 - 3.3 8.1 6.6 1.9 8.9 1.2 3.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 KFH41160.1 - 3.8 8.0 12.7 6.4 7.2 0.3 4.6 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Spc7 PF08317.11 KFH41160.1 - 4.8 6.0 12.5 1.2 8.0 3.7 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KFH41160.1 - 5.7 5.9 9.8 0.43 9.6 2.7 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Allexi_40kDa PF05549.11 KFH41160.1 - 6.5 6.2 7.0 9.8 5.6 0.7 2.6 1 1 0 2 2 2 0 Allexivirus 40kDa protein CorA PF01544.18 KFH41160.1 - 8.8 5.5 7.1 4.7 6.4 0.9 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein PALP PF00291.25 KFH41161.1 - 6.6e-58 196.4 1.0 8.3e-58 196.1 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 KFH41162.1 - 3.3e-49 167.9 0.0 4.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KFH41163.1 - 0.011 16.0 0.0 0.098 12.9 0.0 2.4 1 1 0 1 1 1 0 BTB/POZ domain TauD PF02668.16 KFH41164.1 - 5.4e-47 160.8 0.3 9.5e-47 160.0 0.3 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PAP2_3 PF14378.6 KFH41165.1 - 7.7e-27 94.2 11.2 1.3e-20 74.0 0.8 2.6 2 0 0 2 2 2 2 PAP2 superfamily RtcB PF01139.17 KFH41165.1 - 0.063 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB TctB PF07331.11 KFH41165.1 - 0.33 11.2 9.6 0.092 13.0 0.6 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family YTH PF04146.15 KFH41167.1 - 1.5e-63 213.7 0.1 3e-63 212.7 0.1 1.5 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KFH41167.1 - 0.00055 19.7 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_efflux PF01545.21 KFH41168.1 - 1.9e-23 83.2 10.3 2.5e-23 82.9 10.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFH41168.1 - 2.7e-08 33.8 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Rad51 PF08423.11 KFH41169.1 - 1.9e-126 420.5 0.0 2.3e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFH41169.1 - 4.6e-09 36.1 0.0 7.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFH41169.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFH41169.1 - 2.2e-07 31.4 0.6 1.2e-06 29.0 0.2 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFH41169.1 - 2.1e-05 24.0 0.0 4.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KFH41169.1 - 0.0087 15.4 0.1 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFH41169.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFH41169.1 - 0.13 12.3 0.3 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain HHH PF00633.23 KFH41169.1 - 0.14 12.0 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_5 PF13854.6 KFH41171.1 - 2.3e-16 59.3 1.1 2.9e-08 33.5 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KFH41171.1 - 5.4e-12 45.5 6.4 0.079 13.0 0.0 6.0 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFH41171.1 - 1.3e-10 41.2 4.1 0.041 14.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFH41171.1 - 1.1e-08 35.2 6.0 0.011 16.1 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFH41171.1 - 9.6e-07 28.3 4.9 0.012 15.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KFH41171.1 - 1.4e-05 24.8 4.0 0.018 15.0 0.1 4.3 5 0 0 5 5 5 2 Kelch motif HSP20 PF00011.21 KFH41172.1 - 2.5e-18 66.1 0.0 1.5e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFH41172.1 - 6.4e-06 25.6 0.0 0.0052 16.3 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA DUF5542 PF17696.1 KFH41172.1 - 8.2 6.6 6.8 2.6 8.2 0.4 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5542) Proteasome PF00227.26 KFH41173.1 - 2.6e-28 98.8 0.2 1.4e-27 96.5 0.3 1.9 2 1 0 2 2 2 1 Proteasome subunit Nup160 PF11715.8 KFH41174.1 - 2e-130 436.0 0.0 3e-130 435.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_L6 PF00347.23 KFH41175.1 - 5.7e-25 87.8 9.5 1.5e-13 51.2 3.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PI3_PI4_kinase PF00454.27 KFH41176.1 - 6.9e-41 140.7 0.1 1.3e-38 133.2 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFH41176.1 - 7.7e-25 87.4 0.0 1.9e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) V-ATPase_H_N PF03224.14 KFH41177.1 - 7.5e-75 252.1 0.0 9.4e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFH41177.1 - 1.2e-34 119.0 0.0 4.2e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_EZ PF13513.6 KFH41177.1 - 0.018 15.6 0.3 17 6.0 0.1 3.4 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 KFH41177.1 - 0.027 14.8 2.1 0.27 11.6 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats Arm PF00514.23 KFH41177.1 - 0.069 13.2 0.0 24 5.1 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFH41177.1 - 0.14 12.5 0.0 3.9 8.0 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat HATPase_c_3 PF13589.6 KFH41180.1 - 6.6e-14 51.9 0.7 2.2e-13 50.2 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KFH41180.1 - 8.2e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFH41180.1 - 4e-08 33.7 0.3 9.9e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Metallophos PF00149.28 KFH41182.1 - 1.4e-11 45.3 1.8 2.5e-11 44.5 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GEN1_C PF18380.1 KFH41182.1 - 5.1 8.1 11.3 21 6.1 0.6 3.5 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain GCV_T PF01571.21 KFH41183.1 - 2.8e-77 259.6 0.0 3.5e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KFH41183.1 - 1.2e-22 79.6 0.4 2.7e-22 78.5 0.4 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TraK PF06586.11 KFH41184.1 - 0.15 11.7 1.8 0.24 11.0 1.8 1.2 1 0 0 1 1 1 0 TraK protein DUF4690 PF15756.5 KFH41184.1 - 0.71 10.5 9.1 0.096 13.3 3.3 2.6 3 0 0 3 3 3 0 Small Novel Rich in Cartilage TPPK_C PF12555.8 KFH41184.1 - 6.3 6.9 6.9 91 3.2 0.0 3.2 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Vps26 PF03643.15 KFH41185.1 - 1.4e-129 431.0 0.6 1.7e-129 430.7 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFH41185.1 - 0.003 17.6 0.7 2.9 8.0 0.0 3.4 1 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KFH41185.1 - 0.065 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D DHHC PF01529.20 KFH41186.1 - 4.1e-32 111.1 1.5 4.1e-32 111.1 1.5 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Lyase_aromatic PF00221.19 KFH41187.1 - 8.6e-153 509.3 8.3 1.1e-152 508.9 8.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Pribosyltran_N PF13793.6 KFH41188.1 - 2.4e-44 150.0 0.0 1.5e-42 144.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFH41188.1 - 1.4e-34 119.7 0.2 5.7e-28 98.2 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFH41188.1 - 7.4e-12 45.1 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4392 PF14336.6 KFH41188.1 - 0.025 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) MORN PF02493.20 KFH41189.1 - 0.088 12.7 2.3 1.6 8.8 0.2 3.1 2 0 0 2 2 2 0 MORN repeat CENP-B_dimeris PF09026.10 KFH41189.1 - 0.27 11.6 11.0 0.1 13.0 7.6 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain APG12 PF04110.13 KFH41191.1 - 2.8e-26 91.7 0.0 3.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KFH41191.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Peptidase_M24 PF00557.24 KFH41192.1 - 1.1e-50 172.2 0.0 2.3e-50 171.2 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 KFH41192.1 - 5.6e-36 123.0 0.0 9.5e-36 122.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 KFH41194.1 - 2.7e-41 140.8 0.0 8.9e-41 139.1 0.0 2.0 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KFH41194.1 - 3.8e-21 74.9 0.2 6.3e-21 74.2 0.2 1.3 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KFH41194.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 KFH41194.1 - 0.19 12.1 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Rap1_C PF11626.8 KFH41196.1 - 1.2e-21 76.6 0.5 2.7e-21 75.4 0.1 1.9 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KFH41196.1 - 1.2e-16 60.6 0.2 2.8e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 Rap1 Myb domain ARID PF01388.21 KFH41196.1 - 1.9e-11 44.5 0.0 4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BRCT_2 PF16589.5 KFH41196.1 - 3e-10 40.3 0.0 5.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KFH41196.1 - 0.0047 17.5 0.3 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 Rap1, DNA-binding DUF58 PF01882.18 KFH41196.1 - 0.055 13.7 0.0 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF58 UBA PF00627.31 KFH41196.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF572 PF04502.13 KFH41197.1 - 1e-59 202.9 0.0 1.2e-59 202.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) FlgN PF05130.12 KFH41197.1 - 0.12 12.8 0.7 0.23 12.0 0.7 1.3 1 0 0 1 1 1 0 FlgN protein CAP_N PF01213.19 KFH41197.1 - 4.7 6.6 8.0 7.9 5.9 8.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFH41197.1 - 6.8 6.8 6.5 12 6.0 6.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Flavoprotein PF02441.19 KFH41201.1 - 1.6e-18 66.9 0.0 2.9e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DCB PF16213.5 KFH41202.1 - 1.1e-48 165.3 7.2 2.6e-47 160.8 5.1 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFH41202.1 - 1.1e-42 145.6 3.0 1.5e-41 142.0 0.1 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KFH41202.1 - 2.5e-27 95.4 4.9 8.5e-21 73.8 1.8 3.4 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KFH41202.1 - 0.00029 20.6 0.5 0.022 14.6 0.0 4.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Band_7 PF01145.25 KFH41203.1 - 4.5e-31 108.2 0.4 7.7e-31 107.5 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFH41203.1 - 5.7e-24 84.0 0.3 1.4e-23 82.7 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KFH41203.1 - 0.0081 15.5 0.7 0.02 14.2 0.6 1.6 1 1 1 2 2 2 2 Poxvirus A11 Protein Tht1 PF04163.12 KFH41204.1 - 1.3e-05 24.2 0.0 4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein KxDL PF10241.9 KFH41204.1 - 0.033 14.5 1.6 0.91 9.8 0.0 3.0 1 1 3 4 4 4 0 Uncharacterized conserved protein Selenoprotein_S PF06936.11 KFH41204.1 - 0.076 12.8 1.3 0.14 12.0 1.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) ZYG-11_interact PF05884.12 KFH41204.1 - 0.19 11.1 0.1 8.6 5.7 0.2 2.2 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF3782 PF12644.7 KFH41204.1 - 0.32 11.2 2.7 22 5.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Spc7 PF08317.11 KFH41204.1 - 0.46 9.3 8.8 0.85 8.4 1.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KFH41204.1 - 0.48 10.7 3.3 3 8.2 0.7 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain Mer2 PF09074.10 KFH41204.1 - 0.7 9.7 5.1 0.24 11.2 0.3 2.1 1 1 0 2 2 2 0 Mer2 GIT1_C PF12205.8 KFH41204.1 - 0.86 9.7 8.4 0.14 12.3 2.0 2.8 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF3450 PF11932.8 KFH41204.1 - 0.86 8.9 11.7 0.17 11.2 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 KFH41204.1 - 1.6 8.8 6.3 0.59 10.2 0.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.9 KFH41204.1 - 2.4 8.2 6.8 5.6 7.0 0.2 3.5 3 1 1 4 4 4 0 Short coiled-coil protein GCN5L1 PF06320.13 KFH41204.1 - 3.6 7.7 7.5 0.95 9.6 1.4 2.6 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) BST2 PF16716.5 KFH41204.1 - 4.3 8.0 8.8 2.9 8.5 0.2 3.0 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 CLZ PF16526.5 KFH41204.1 - 4.4 7.7 6.6 13 6.3 0.8 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nup54 PF13874.6 KFH41204.1 - 5.1 7.2 13.0 0.11 12.6 0.7 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Remorin_C PF03763.13 KFH41204.1 - 5.2 7.0 6.9 2.3 8.1 0.2 2.8 1 1 3 4 4 4 0 Remorin, C-terminal region Syntaxin-6_N PF09177.11 KFH41204.1 - 5.8 7.5 9.7 6.7 7.3 1.0 3.3 2 1 1 4 4 3 0 Syntaxin 6, N-terminal DUF2203 PF09969.9 KFH41204.1 - 8.8 7.1 8.3 4.4 8.0 0.2 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pantoate_transf PF02548.15 KFH41205.1 - 7.6e-104 346.7 0.3 8.9e-104 346.5 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KFH41205.1 - 4.5e-08 32.8 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.26 KFH41206.1 - 5.9e-16 58.4 0.0 6.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFH41206.1 - 0.0079 16.5 0.0 0.0084 16.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFH41206.1 - 0.032 14.1 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 UEV domain Aha1_N PF09229.11 KFH41207.1 - 2.8e-37 128.0 0.1 5.3e-37 127.1 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFH41207.1 - 2.1e-18 66.7 0.3 4.1e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein UQ_con PF00179.26 KFH41208.1 - 3.6e-34 117.4 0.1 4.3e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_20 PF00728.22 KFH41210.1 - 1.1e-25 90.7 2.1 1.6e-18 67.2 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KFH41210.1 - 1.3e-08 35.6 0.0 3.8e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BetaGal_dom4_5 PF13364.6 KFH41210.1 - 0.012 16.2 0.3 0.073 13.6 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Complex1_LYR PF05347.15 KFH41211.1 - 1.2e-05 25.3 2.7 1.2e-05 25.3 2.7 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFH41211.1 - 0.011 16.5 6.9 0.036 14.8 6.9 2.1 1 1 0 1 1 1 0 Complex1_LYR-like Con-6 PF10346.9 KFH41212.1 - 2.5e-14 53.0 0.4 2.5e-14 53.0 0.4 1.6 2 0 0 2 2 2 1 Conidiation protein 6 CENP-L PF13092.6 KFH41213.1 - 1.4e-54 184.7 0.0 1.9e-53 181.0 0.0 2.0 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 Abhydrolase_5 PF12695.7 KFH41214.1 - 0.0017 18.1 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KFH41214.1 - 0.0085 16.7 0.2 0.017 15.7 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 KFH41214.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 KFH41214.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KFH41214.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 KFH41214.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase UDPG_MGDP_dh_N PF03721.14 KFH41215.1 - 2.6e-48 164.1 0.0 1.8e-29 102.7 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KFH41215.1 - 3.8e-31 107.1 0.0 8.1e-31 106.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KFH41215.1 - 8.1e-23 80.8 0.0 5.8e-18 65.2 0.0 3.0 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KFH41215.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KFH41215.1 - 0.01 16.0 0.0 0.23 11.6 0.0 2.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFH41215.1 - 0.044 13.9 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KFH41215.1 - 0.068 13.2 0.0 8.7 6.3 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KFH41215.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 KFH41217.1 - 2.6e-16 59.9 0.0 7e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFH41217.1 - 2.9e-09 36.8 0.0 4.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFH41217.1 - 2.2e-08 34.4 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH41217.1 - 4.2e-08 33.2 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFH41217.1 - 0.00052 20.7 0.0 0.0008 20.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KFH41217.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 KFH41217.1 - 0.037 14.2 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFH41217.1 - 0.046 13.2 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KFH41217.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase EthD PF07110.11 KFH41218.1 - 1.5e-24 86.9 0.2 1.8e-24 86.7 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFH41218.1 - 2.2e-07 31.3 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Glycos_transf_1 PF00534.20 KFH41220.1 - 9.2e-33 113.2 0.0 1.6e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH41220.1 - 1.3e-28 100.1 0.0 2.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFH41220.1 - 4.3e-12 46.7 0.0 1.1e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KFH41220.1 - 2.9e-11 43.7 0.0 9.4e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFH41220.1 - 6.7e-10 39.2 0.0 4.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF485 PF04341.12 KFH41220.1 - 0.073 13.0 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 GlgS PF08971.11 KFH41220.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein NAD_binding_10 PF13460.6 KFH41221.1 - 2e-07 31.1 0.0 2.3e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KFH41221.1 - 0.0053 16.9 0.3 0.01 16.0 0.3 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KFH41221.1 - 0.016 14.6 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFH41221.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Ank_4 PF13637.6 KFH41222.1 - 9.3e-13 48.4 0.8 7.3e-07 29.6 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH41222.1 - 2.7e-10 39.6 0.3 0.004 17.5 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KFH41222.1 - 3.9e-10 40.2 0.0 0.0016 18.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFH41222.1 - 5.6e-09 36.0 2.6 0.026 15.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFH41222.1 - 3.5e-06 27.2 0.1 0.11 12.8 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KFH41222.1 - 0.00022 21.0 0.7 0.002 18.0 0.3 2.5 2 1 0 2 2 2 1 KilA-N domain ATPase PF06745.13 KFH41222.1 - 0.041 13.2 0.9 0.082 12.2 0.9 1.4 1 0 0 1 1 1 0 KaiC LMBR1 PF04791.16 KFH41222.1 - 0.096 11.6 0.3 0.14 11.1 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prp18 PF02840.15 KFH41222.1 - 0.15 12.1 2.5 0.26 11.3 2.0 1.6 2 0 0 2 2 2 0 Prp18 domain Hrs_helical PF12210.8 KFH41222.1 - 0.31 11.6 2.8 2.3 8.8 3.9 1.8 2 0 0 2 2 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Filament PF00038.21 KFH41222.1 - 0.35 10.4 5.0 0.69 9.4 5.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.19 KFH41222.1 - 0.64 7.9 1.8 0.99 7.2 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliJ PF02050.16 KFH41222.1 - 4.6 7.5 13.3 0.21 11.8 5.7 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 KFH41223.1 - 1.7e-19 70.0 31.4 2.2e-12 46.6 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41223.1 - 1.2e-15 57.4 15.2 2e-15 56.6 15.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter PDGLE PF13190.6 KFH41224.1 - 0.13 12.1 0.2 8.1 6.4 0.2 2.5 1 1 0 1 1 1 0 PDGLE domain 5_nucleotid_C PF02872.18 KFH41225.1 - 7.5e-41 140.0 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFH41225.1 - 0.082 13.4 0.1 1.2 9.5 0.0 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase FYVE PF01363.21 KFH41227.1 - 4.9e-25 87.5 20.7 3.7e-18 65.4 5.4 3.2 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KFH41227.1 - 3.2e-16 58.8 1.4 6.8e-16 57.7 1.4 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KFH41227.1 - 0.00021 21.4 2.6 0.00021 21.4 2.6 4.0 4 1 1 5 5 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFH41227.1 - 0.025 14.9 0.1 0.025 14.9 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KFH41227.1 - 0.034 14.4 1.0 0.034 14.4 1.0 3.6 3 1 0 3 3 2 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 KFH41227.1 - 0.16 11.9 2.4 8 6.4 0.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFH41227.1 - 0.68 10.3 0.0 0.68 10.3 0.0 3.2 5 0 0 5 5 2 0 C2H2 type zinc-finger (2 copies) Prefoldin_2 PF01920.20 KFH41227.1 - 1 9.3 6.2 3.5 7.6 0.2 3.3 3 0 0 3 3 3 0 Prefoldin subunit zf-C2H2_4 PF13894.6 KFH41227.1 - 1.3 10.1 0.0 1.3 10.1 0.0 6.1 5 1 1 6 6 6 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KFH41227.1 - 2.5 7.6 12.9 4 7.0 0.4 4.8 5 0 0 5 5 5 0 zinc-ribbon domain TMF_TATA_bd PF12325.8 KFH41227.1 - 3.6 7.9 12.8 0.11 12.8 3.8 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 KFH41227.1 - 3.7 8.0 7.1 11 6.4 0.2 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain CtIP_N PF10482.9 KFH41227.1 - 5.8 7.0 11.3 22 5.1 1.7 3.8 3 2 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DZR PF12773.7 KFH41227.1 - 6 7.0 19.7 3.4 7.8 1.6 4.0 4 1 0 4 4 4 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 KFH41227.1 - 7.6 6.6 7.3 50 4.0 0.0 4.0 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zinc_ribbon_9 PF14369.6 KFH41227.1 - 8.9 6.7 11.5 3.8 7.9 0.2 3.9 4 0 0 4 4 3 0 zinc-ribbon zf-C2HC5 PF06221.13 KFH41227.1 - 9.8 6.3 18.2 4.4 7.4 0.1 4.8 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type ADH_zinc_N PF00107.26 KFH41228.1 - 3.3e-25 88.6 0.1 5e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH41228.1 - 1.3e-14 55.4 0.0 3.1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41228.1 - 1e-10 41.4 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KFH41228.1 - 0.019 14.2 0.3 0.031 13.6 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAGK_cat PF00781.24 KFH41228.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Dehydratase_hem PF13816.6 KFH41229.1 - 1.7e-99 333.1 0.4 1.9e-99 333.0 0.4 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KFH41229.1 - 1.4e-08 35.1 0.5 5.4e-05 23.5 0.3 3.0 3 1 0 3 3 3 2 Domain of unknown function (DUF4188) DUF3328 PF11807.8 KFH41230.1 - 0.058 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) NAD_binding_7 PF13241.6 KFH41231.1 - 1.6e-31 108.8 0.0 3.7e-31 107.7 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KFH41231.1 - 4.5e-27 93.5 0.0 6.9e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KFH41231.1 - 1.2e-15 56.6 0.1 1.9e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KFH41231.1 - 0.00025 20.4 0.0 0.00035 19.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase LSDAT_prok PF18171.1 KFH41231.1 - 0.056 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Shikimate_DH PF01488.20 KFH41231.1 - 0.063 13.3 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFH41231.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KFH41231.1 - 0.12 11.7 1.2 0.2 11.0 0.0 1.8 1 1 0 2 2 2 0 ThiF family Prenyltrans PF00432.21 KFH41232.1 - 1.6e-31 107.7 26.3 3e-07 30.1 0.9 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFH41232.1 - 0.00063 18.9 0.1 0.0029 16.7 0.1 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFH41232.1 - 0.0035 16.5 0.1 0.99 8.4 0.1 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain DND1_DSRM PF14709.7 KFH41233.1 - 0.0014 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KFH41233.1 - 0.022 15.5 0.0 0.041 14.6 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF755 PF05501.11 KFH41233.1 - 0.75 10.1 10.6 1 9.7 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Acyltransferase PF01553.21 KFH41235.1 - 1.9e-10 40.5 0.0 2.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase VHS PF00790.19 KFH41236.1 - 7e-41 139.4 4.6 1.1e-40 138.8 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KFH41236.1 - 2.8e-15 56.2 5.0 5.9e-15 55.2 5.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KFH41236.1 - 3.2e-05 23.5 16.9 0.0066 16.3 1.1 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KFH41236.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.9 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 KFH41236.1 - 0.043 14.0 1.8 0.096 12.9 1.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_2 PF12797.7 KFH41236.1 - 1.3 9.3 7.6 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AMP-binding PF00501.28 KFH41237.1 - 6.6e-84 281.9 0.0 8.9e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BRAP2 PF07576.12 KFH41238.1 - 3.2e-28 97.9 0.0 6.9e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KFH41238.1 - 1.4e-19 70.2 6.1 3.1e-19 69.1 6.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KFH41238.1 - 8.2e-09 35.7 9.3 8.2e-09 35.7 9.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KFH41238.1 - 7.3e-07 28.8 5.1 7.3e-07 28.8 5.1 2.2 2 1 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFH41238.1 - 5.5e-06 26.1 9.1 5.5e-06 26.1 9.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH41238.1 - 7e-06 25.8 8.0 7e-06 25.8 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH41238.1 - 1.1e-05 25.2 18.1 0.00035 20.4 7.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH41238.1 - 5.6e-05 23.0 7.4 5.6e-05 23.0 7.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH41238.1 - 0.00023 21.1 6.6 0.00023 21.1 6.6 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFH41238.1 - 0.0018 18.5 6.6 0.0018 18.5 6.6 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain TPR_MLP1_2 PF07926.12 KFH41238.1 - 0.0026 17.8 15.0 0.0055 16.8 15.0 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein MCC-bdg_PDZ PF10506.9 KFH41238.1 - 0.032 14.3 2.1 0.087 12.9 0.7 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3584 PF12128.8 KFH41238.1 - 0.04 11.5 10.9 0.056 11.0 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prok-RING_4 PF14447.6 KFH41238.1 - 0.096 12.6 21.5 0.086 12.7 10.8 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFH41238.1 - 0.11 12.5 6.0 0.3 11.2 6.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HeLo PF14479.6 KFH41238.1 - 0.31 10.8 5.1 0.53 10.1 5.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Exonuc_VII_L PF02601.15 KFH41238.1 - 0.34 10.4 9.3 0.65 9.5 9.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit EzrA PF06160.12 KFH41238.1 - 0.41 8.8 12.6 0.58 8.3 12.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA COG5 PF10392.9 KFH41238.1 - 0.45 10.7 5.6 0.87 9.8 5.6 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NRBF2 PF08961.10 KFH41238.1 - 0.69 9.5 8.8 1.2 8.7 8.8 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator zf-RING_4 PF14570.6 KFH41238.1 - 0.77 9.6 6.8 2 8.3 6.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ZapB PF06005.12 KFH41238.1 - 0.9 10.0 18.6 3 8.3 5.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB CENP-Q PF13094.6 KFH41238.1 - 1.4 9.1 14.0 3.4 7.9 14.0 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF465 PF04325.13 KFH41238.1 - 1.6 8.9 5.4 1.6 8.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) zf-RING_6 PF14835.6 KFH41238.1 - 2.5 8.0 10.5 0.044 13.7 3.2 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KFH41238.1 - 3 7.6 15.1 1.5 8.5 5.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DivIC PF04977.15 KFH41238.1 - 3 7.7 6.2 0.59 10.0 1.0 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KFH41238.1 - 3.2 7.0 8.8 5.8 6.2 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KFH41238.1 - 7.8 5.7 14.3 3.6 6.8 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 KFH41238.1 - 8.8 7.1 8.6 1.3 9.8 3.5 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Glyco_hydro_28 PF00295.17 KFH41239.1 - 3.6e-36 124.9 0.4 5.4e-36 124.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SnoaL PF07366.12 KFH41239.1 - 0.099 12.5 0.8 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Beta_helix PF13229.6 KFH41239.1 - 1.3 8.8 13.5 1.3 8.9 11.1 2.1 1 1 1 2 2 2 0 Right handed beta helix region SAP130_C PF16014.5 KFH41240.1 - 0.11 11.5 0.8 0.12 11.5 0.8 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Suc_Fer-like PF06999.12 KFH41241.1 - 1.2e-70 237.4 0.0 1.4e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like His_Phos_1 PF00300.22 KFH41242.1 - 1.7e-17 63.8 1.4 9e-17 61.4 0.0 2.1 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) UCH PF00443.29 KFH41243.1 - 9.5e-30 103.9 0.0 1.5e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH41243.1 - 6.5e-12 45.7 0.0 1.6e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KFH41243.1 - 2.4e-06 28.0 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF5538 PF17692.1 KFH41244.1 - 0.087 12.9 7.2 0.097 12.7 7.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Zn_clus PF00172.18 KFH41245.1 - 0.0041 17.2 7.7 0.0085 16.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 KFH41246.1 - 7e-70 234.8 2.3 1.1e-69 234.1 1.9 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFH41246.1 - 1.5e-62 211.4 0.0 2.1e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Cupin_1 PF00190.22 KFH41247.1 - 1.1e-06 28.4 0.1 1.6e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFH41247.1 - 2.2e-06 27.3 0.2 2.2e-06 27.3 0.2 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.7 KFH41247.1 - 0.035 13.8 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Cupin 3-HAO PF06052.12 KFH41247.1 - 0.061 13.0 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase PalH PF08733.10 KFH41248.1 - 1.1e-112 376.3 0.0 1.3e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF1771 PF08590.10 KFH41249.1 - 3.3e-23 81.8 9.8 3.3e-23 81.8 9.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFH41249.1 - 2.2e-10 40.8 2.7 2.4e-10 40.6 0.4 2.2 2 0 0 2 2 2 1 Smr domain SUIM_assoc PF16619.5 KFH41249.1 - 0.0047 17.0 0.0 0.0078 16.2 0.0 1.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4407 PF14362.6 KFH41249.1 - 0.78 9.0 5.0 0.22 10.9 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TRAM_LAG1_CLN8 PF03798.16 KFH41250.1 - 2.4e-37 128.6 18.0 4.3e-37 127.8 18.0 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KFH41250.1 - 3.1e-25 87.6 3.1 7.4e-24 83.2 0.0 2.6 2 0 0 2 2 2 2 TRAM1-like protein AAA PF00004.29 KFH41251.1 - 1.1e-97 323.5 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH41251.1 - 3.2e-22 78.1 6.4 9.9e-13 47.7 0.4 3.3 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KFH41251.1 - 5.2e-19 68.2 0.4 2.1e-18 66.3 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFH41251.1 - 2.2e-14 53.5 0.0 3.2e-06 27.0 0.0 3.5 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFH41251.1 - 9.4e-14 51.9 0.0 2.1e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFH41251.1 - 1.2e-12 48.5 0.0 0.0011 19.3 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KFH41251.1 - 2.8e-12 47.0 0.0 4.4e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KFH41251.1 - 8.7e-12 45.2 0.5 3.4e-06 27.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH41251.1 - 1.3e-09 38.5 0.3 0.023 15.0 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KFH41251.1 - 3.3e-09 36.4 0.0 0.0011 18.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KFH41251.1 - 4.5e-08 32.7 0.3 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KFH41251.1 - 1.7e-07 31.8 0.0 0.028 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFH41251.1 - 2.1e-07 30.8 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFH41251.1 - 2.2e-07 30.5 0.3 0.0073 15.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFH41251.1 - 2.7e-07 30.7 0.0 0.0082 16.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KFH41251.1 - 8.4e-07 28.7 4.5 0.4 10.2 0.1 4.7 3 2 1 5 5 5 3 AAA domain RNA_helicase PF00910.22 KFH41251.1 - 1.6e-06 28.4 0.0 0.092 13.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KFH41251.1 - 2e-06 27.4 0.4 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KFH41251.1 - 2.2e-06 27.3 0.0 0.038 13.5 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KFH41251.1 - 1e-05 25.5 0.2 0.00011 22.2 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KFH41251.1 - 1.4e-05 25.4 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFH41251.1 - 2.3e-05 24.2 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 KFH41251.1 - 2.4e-05 24.9 0.0 0.27 11.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 KFH41251.1 - 2.9e-05 23.8 0.1 0.24 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KFH41251.1 - 3.5e-05 23.0 0.0 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KFH41251.1 - 4.3e-05 22.8 0.0 0.076 12.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PhoH PF02562.16 KFH41251.1 - 0.00014 21.4 0.3 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 KFH41251.1 - 0.00016 21.7 0.0 0.97 9.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KFH41251.1 - 0.00019 21.4 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein ResIII PF04851.15 KFH41251.1 - 0.00027 21.0 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KFH41251.1 - 0.00027 20.8 0.0 0.68 9.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFH41251.1 - 0.00028 21.3 0.0 0.6 10.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFH41251.1 - 0.00037 20.5 0.1 0.44 10.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KFH41251.1 - 0.00045 20.0 0.2 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KFH41251.1 - 0.0012 18.8 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH41251.1 - 0.0016 18.8 0.9 5.2 7.4 0.0 3.6 3 1 1 4 4 3 0 AAA domain ATPase_2 PF01637.18 KFH41251.1 - 0.0027 17.7 0.0 1.9 8.4 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KFH41251.1 - 0.0032 17.6 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 KFH41251.1 - 0.0042 16.4 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KFH41251.1 - 0.0058 16.5 0.6 2.6 7.9 0.0 3.8 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 KFH41251.1 - 0.0076 16.0 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KFH41251.1 - 0.0096 15.1 0.0 3.1 6.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 KFH41251.1 - 0.012 14.9 0.0 0.87 8.8 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain IPT PF01745.16 KFH41251.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 KFH41251.1 - 0.021 14.1 0.6 7.8 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin UFD1 PF03152.14 KFH41251.1 - 0.045 13.2 0.0 0.15 11.5 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 KFH41251.1 - 0.059 13.1 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 KFH41251.1 - 0.06 12.3 0.3 7.6 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 KFH41251.1 - 0.1 11.5 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase CDC27 PF09507.10 KFH41253.1 - 0.0024 17.4 1.2 0.0028 17.1 1.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 EnY2 PF10163.9 KFH41253.1 - 0.0047 17.3 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Transcription factor e(y)2 Suf PF05843.14 KFH41253.1 - 0.094 12.7 0.4 0.095 12.7 0.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 KFH41253.1 - 0.14 10.7 2.5 0.13 10.7 2.5 1.1 1 0 0 1 1 1 0 Macoilin family RSF PF14876.6 KFH41253.1 - 0.18 10.8 1.5 0.21 10.5 1.5 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Ashwin PF15323.6 KFH41253.1 - 0.83 9.6 6.5 1.2 9.2 6.5 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.9 KFH41253.1 - 1.5 8.4 10.7 2.2 7.9 10.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 KFH41253.1 - 3.2 8.1 18.6 2.5 8.5 12.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain KTI12 PF08433.10 KFH41254.1 - 2.5e-72 243.6 0.0 4.5e-72 242.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFH41254.1 - 5.2e-05 23.4 0.0 8.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH41254.1 - 6.5e-05 23.5 0.0 0.00032 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KFH41254.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 KFH41254.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFH41254.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH41254.1 - 0.075 13.4 0.1 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain GT-D PF08759.11 KFH41254.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold YjeF_N PF03853.15 KFH41256.1 - 8.9e-38 129.8 0.0 1.9e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KFH41256.1 - 1.6e-06 28.9 1.5 1.6e-06 28.9 1.5 2.7 2 0 0 2 2 2 1 FDF domain U1snRNP70_N PF12220.8 KFH41256.1 - 0.057 14.1 1.9 0.17 12.6 1.9 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rrn6 PF10214.9 KFH41256.1 - 0.62 8.5 12.0 0.057 11.9 6.2 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor ABC_tran PF00005.27 KFH41257.1 - 9.2e-34 116.9 0.0 2.2e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KFH41257.1 - 2.4e-22 79.9 7.1 2.4e-22 79.9 7.1 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KFH41257.1 - 4.2e-05 23.1 0.0 0.00017 21.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFH41257.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KFH41257.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFH41257.1 - 0.083 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KFH41257.1 - 0.099 12.9 0.2 3.2 8.1 0.2 3.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AF-4 PF05110.13 KFH41257.1 - 2.7 6.0 8.4 3.9 5.4 8.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PIF1 PF05970.14 KFH41258.1 - 2.9e-60 204.4 0.0 2.6e-46 158.5 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KFH41258.1 - 2.8e-22 79.4 0.0 4.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH41258.1 - 6.9e-12 45.9 0.0 1.4e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFH41258.1 - 1.8e-07 31.5 0.0 3.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFH41258.1 - 7.4e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 KFH41258.1 - 5.1e-05 21.4 0.0 0.00016 19.8 0.0 1.6 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KFH41258.1 - 9.9e-05 22.1 0.8 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 KFH41258.1 - 0.00017 20.8 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KFH41258.1 - 0.00022 21.6 0.0 0.00069 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFH41258.1 - 0.00025 21.5 0.0 0.00054 20.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KFH41258.1 - 0.0023 17.4 0.0 0.006 16.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.27 KFH41258.1 - 0.0035 17.9 0.0 0.0098 16.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 KFH41258.1 - 0.0035 17.3 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 KFH41258.1 - 0.0046 16.8 3.2 0.0048 16.7 0.0 2.5 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KFH41258.1 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ResIII PF04851.15 KFH41258.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KFH41258.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFH41258.1 - 0.019 14.7 0.0 0.28 10.9 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KFH41258.1 - 0.02 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KFH41258.1 - 0.024 14.4 0.0 0.076 12.7 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KFH41258.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 KFH41258.1 - 0.027 14.2 0.0 0.66 9.7 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KFH41258.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KFH41258.1 - 0.063 13.3 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFH41258.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2314 PF10077.9 KFH41258.1 - 0.082 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) RsgA_GTPase PF03193.16 KFH41258.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KFH41258.1 - 0.12 12.4 0.1 1.1 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 KFH41258.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SH3_13 PF18335.1 KFH41258.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NTPase_1 PF03266.15 KFH41258.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase TIP49 PF06068.13 KFH41258.1 - 0.21 10.8 0.0 1.3 8.1 0.0 2.1 3 0 0 3 3 3 0 TIP49 P-loop domain Exo_endo_phos PF03372.23 KFH41260.1 - 0.00031 20.4 0.2 0.00074 19.1 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CW_binding_1 PF01473.20 KFH41260.1 - 0.059 13.7 1.2 0.21 12.0 1.0 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat UCH PF00443.29 KFH41261.1 - 1.7e-47 162.1 0.0 2.1e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFH41261.1 - 8.6e-12 44.6 0.1 1.9e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 KFH41261.1 - 1.6e-11 44.4 5.5 1.8e-10 40.9 5.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn_clus PF00172.18 KFH41262.1 - 0.0026 17.9 1.5 0.0042 17.2 1.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41263.1 - 1.1e-25 90.3 1.2 7e-25 87.6 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KFH41263.1 - 1.7e-09 37.7 1.7 7e-09 35.7 0.3 2.5 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.18 KFH41263.1 - 2.4e-07 30.8 9.6 3.7e-07 30.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LAGLIDADG_2 PF03161.13 KFH41263.1 - 0.014 15.5 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Fungal_trans_2 PF11951.8 KFH41264.1 - 1.4e-08 34.0 0.1 2.4e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41264.1 - 4e-06 26.9 6.9 9.4e-06 25.7 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigB PF02900.18 KFH41264.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF594 PF04578.13 KFH41264.1 - 0.082 12.5 0.3 3.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF594 CRAL_TRIO PF00650.20 KFH41265.1 - 9.6e-14 51.4 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH41265.1 - 2.4e-05 24.4 0.0 7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Sugar_tr PF00083.24 KFH41267.1 - 3e-120 402.1 15.3 5.5e-120 401.3 15.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41267.1 - 1.5e-21 76.7 53.1 4.3e-12 45.6 23.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Wzy_C_2 PF11846.8 KFH41268.1 - 0.1 12.5 0.2 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ARPC4 PF05856.12 KFH41269.1 - 1.2e-76 256.0 2.8 1.3e-76 255.9 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF1902 PF08972.11 KFH41269.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) CBP PF12192.8 KFH41270.1 - 5.7e-06 26.4 5.7 5.7e-06 26.4 5.7 1.9 1 1 1 2 2 2 1 Fungal calcium binding protein Methyltransf_23 PF13489.6 KFH41271.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH41271.1 - 1.2e-10 41.9 0.0 3.1e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41271.1 - 2.6e-10 40.9 0.0 4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41271.1 - 2.6e-10 40.9 0.0 5.9e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH41271.1 - 3.3e-09 36.4 0.0 5.8e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFH41271.1 - 7.9e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFH41271.1 - 0.014 14.4 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 KFH41271.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KFH41271.1 - 0.033 14.2 0.1 0.066 13.2 0.1 1.5 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFH41271.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DUF3176 PF11374.8 KFH41272.1 - 6.6e-23 81.0 0.0 6.6e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Pam17 PF08566.10 KFH41272.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SET PF00856.28 KFH41273.1 - 7.5e-16 59.0 0.6 7.5e-15 55.7 0.6 2.7 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KFH41273.1 - 1.8e-08 34.2 5.7 6e-08 32.6 5.7 1.9 1 0 0 1 1 1 1 AWS domain WD40 PF00400.32 KFH41274.1 - 1.4e-37 127.0 26.0 5e-08 33.5 0.4 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41274.1 - 1.5e-19 70.1 3.8 0.0013 19.0 0.1 6.0 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH41274.1 - 6.5e-08 31.7 12.2 0.035 12.8 0.4 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 NACHT PF05729.12 KFH41274.1 - 1.5e-06 28.2 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFH41274.1 - 7.7e-06 26.4 0.4 3.3e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain PALB2_WD40 PF16756.5 KFH41274.1 - 0.00062 18.8 2.8 1.2 8.0 0.1 4.1 2 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KFH41274.1 - 0.00076 18.5 8.5 1.4 7.8 0.1 4.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 KFH41274.1 - 0.029 13.6 0.0 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain WD40_like PF17005.5 KFH41274.1 - 0.048 13.0 1.0 7 5.9 0.0 2.9 2 1 0 3 3 3 0 WD40-like domain IKI3 PF04762.12 KFH41274.1 - 0.061 11.3 0.3 4.2 5.2 0.0 2.6 2 0 0 2 2 2 0 IKI3 family APS_kinase PF01583.20 KFH41274.1 - 0.077 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KFH41274.1 - 0.078 12.7 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH41274.1 - 0.087 13.4 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFH41274.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gmad1 PF10647.9 KFH41274.1 - 5.1 6.8 9.7 22 4.7 0.1 3.8 2 2 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain AAA_18 PF13238.6 KFH41275.1 - 2.6e-07 31.3 0.0 1.4e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFH41275.1 - 0.00032 20.0 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KFH41275.1 - 0.00058 20.0 2.0 0.0026 17.9 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFH41275.1 - 0.00099 19.5 0.2 0.002 18.5 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFH41275.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 KFH41275.1 - 0.0017 17.4 0.2 0.0029 16.6 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 KFH41275.1 - 0.0018 18.0 0.2 1.9 8.2 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KFH41275.1 - 0.0023 18.3 0.2 0.21 12.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH41275.1 - 0.032 14.5 0.0 0.072 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFH41275.1 - 0.043 13.3 0.1 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KFH41275.1 - 0.049 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KFH41275.1 - 0.05 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.17 KFH41275.1 - 0.052 13.2 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.27 KFH41275.1 - 0.063 13.8 0.0 0.16 12.5 0.0 1.6 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 KFH41275.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Viral_helicase1 PF01443.18 KFH41275.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase His_Phos_1 PF00300.22 KFH41276.1 - 3.7e-37 127.9 0.3 2e-19 70.0 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HTH_32 PF13565.6 KFH41276.1 - 0.013 16.1 0.1 0.035 14.7 0.1 1.8 1 1 0 1 1 1 0 Homeodomain-like domain WD40 PF00400.32 KFH41277.1 - 4.8e-21 74.7 10.2 3e-05 24.7 1.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41277.1 - 4e-08 33.4 0.0 0.43 10.9 0.0 5.3 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain GSIII_N PF12437.8 KFH41277.1 - 0.0016 18.1 0.2 0.0026 17.4 0.2 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Cytochrom_D1 PF02239.16 KFH41277.1 - 0.056 12.0 0.3 0.9 8.0 0.1 2.6 3 1 0 3 3 3 0 Cytochrome D1 heme domain Inhibitor_I71 PF12628.7 KFH41277.1 - 0.059 13.2 1.0 0.095 12.5 0.6 1.5 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor WD40_like PF17005.5 KFH41277.1 - 0.1 11.9 0.0 2.7 7.2 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain PQQ PF01011.21 KFH41277.1 - 0.32 11.0 4.0 11 6.1 0.0 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat Septin PF00735.18 KFH41278.1 - 4.8e-115 383.7 0.3 7.2e-115 383.1 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFH41278.1 - 1.9e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH41278.1 - 8.2e-06 25.5 4.6 7.8e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH41278.1 - 9.7e-06 25.6 1.9 2.8e-05 24.1 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KFH41278.1 - 0.0017 18.6 0.8 0.0041 17.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KFH41278.1 - 0.0023 17.4 0.1 0.0048 16.4 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KFH41278.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KFH41278.1 - 0.007 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KFH41278.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KFH41278.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFH41278.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 KFH41278.1 - 0.019 14.6 0.7 0.062 12.9 0.5 2.0 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 KFH41278.1 - 0.02 15.3 1.0 0.066 13.6 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain FOXP-CC PF16159.5 KFH41278.1 - 0.029 15.0 1.3 0.029 15.0 1.3 2.5 2 1 1 3 3 1 0 FOXP coiled-coil domain ABC_tran PF00005.27 KFH41278.1 - 0.045 14.3 0.3 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KFH41278.1 - 0.046 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Casc1_N PF15927.5 KFH41278.1 - 0.046 13.4 10.5 0.12 12.1 10.5 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus T2SSE PF00437.20 KFH41278.1 - 0.047 12.7 0.4 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KFH41278.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFH41278.1 - 0.075 12.6 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFH41278.1 - 0.12 12.1 0.4 4.7 7.0 0.4 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KFH41278.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KFH41278.1 - 0.46 10.5 6.9 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KFH41278.1 - 1.2 9.7 6.9 7.8 7.1 0.2 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 KFH41278.1 - 1.7 8.4 7.3 17 5.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain FUSC PF04632.12 KFH41278.1 - 2.1 6.8 4.1 2.8 6.4 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_transf_15 PF01793.16 KFH41279.1 - 3.5e-113 378.1 8.2 4.3e-113 377.8 8.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Alk_phosphatase PF00245.20 KFH41280.1 - 4.8e-69 233.3 0.0 1.7e-68 231.5 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KFH41280.1 - 4e-06 26.7 0.2 7.8e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFH41280.1 - 2.5e-05 23.8 0.2 5.3e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFH41280.1 - 0.0033 16.1 0.1 0.0053 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) BCDHK_Adom3 PF10436.9 KFH41281.1 - 3.5e-45 153.8 0.2 1.2e-44 152.1 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFH41281.1 - 1.6e-06 28.6 0.0 1e-05 26.0 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFH41281.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KFH41281.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain LSM PF01423.22 KFH41281.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 LSM domain Phage_holin_2_1 PF04971.12 KFH41282.1 - 0.11 12.5 0.0 0.47 10.5 0.0 2.0 1 0 0 1 1 1 0 Bacteriophage P21 holin S NAP PF00956.18 KFH41283.1 - 7.9e-27 94.1 7.7 1.7e-26 93.0 1.8 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) U79_P34 PF03064.16 KFH41283.1 - 0.73 9.1 6.1 1.1 8.5 6.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AIM3 PF17096.5 KFH41283.1 - 7.6 7.5 8.8 0.18 12.8 1.2 2.1 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 USP7_ICP0_bdg PF12436.8 KFH41284.1 - 5.4e-83 278.0 0.0 2.9e-81 272.3 0.0 2.6 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFH41284.1 - 7.2e-72 241.4 0.6 3.9e-70 235.7 0.2 3.0 2 1 1 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFH41284.1 - 1.9e-47 161.9 1.7 3.5e-47 161.1 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH41284.1 - 5.9e-20 72.1 0.2 1.4e-19 70.9 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFH41284.1 - 1.5e-09 38.0 0.0 4.6e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 MATH domain Malt_amylase_C PF16657.5 KFH41284.1 - 0.13 12.4 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Abhydrolase_2 PF02230.16 KFH41286.1 - 4.1e-13 49.6 0.0 7.8e-13 48.7 0.0 1.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFH41286.1 - 0.0014 19.2 0.3 0.0018 19.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family KH_5 PF13184.6 KFH41286.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 NusA-like KH domain TGT PF01702.18 KFH41287.1 - 9.9e-62 209.1 0.0 1.3e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase WD-3 PF09765.9 KFH41287.1 - 0.11 11.8 0.0 5.2 6.3 0.0 2.1 2 0 0 2 2 2 0 WD-repeat region AMPKBI PF04739.15 KFH41288.1 - 1.9e-25 88.9 1.0 1.9e-25 88.9 1.0 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KFH41288.1 - 2.5e-25 88.5 0.0 3.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Asparaginase PF00710.20 KFH41289.1 - 9.4e-59 198.2 0.0 1.3e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFH41289.1 - 7.9e-24 84.1 0.0 1.6e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KFH41289.1 - 6.8e-10 39.4 0.3 2.7e-09 37.5 0.2 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH41289.1 - 1.3e-06 28.3 0.5 0.0025 18.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFH41289.1 - 1.9e-06 28.3 0.3 8.7e-05 23.0 0.1 2.8 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH41289.1 - 0.00016 21.9 0.3 0.0015 18.8 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFH41289.1 - 0.0013 19.1 0.1 0.093 13.2 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Fungal_trans PF04082.18 KFH41290.1 - 1.8e-09 37.1 0.0 3.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41290.1 - 4.8e-07 29.8 8.6 8.1e-07 29.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFH41291.1 - 8.7e-66 222.0 0.0 1e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41291.1 - 8e-30 104.0 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH41291.1 - 0.0024 17.3 0.0 0.0049 16.2 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFH41291.1 - 0.0073 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFH41291.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_M22 PF00814.25 KFH41292.1 - 2.8e-83 279.7 0.0 3.4e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family GCP_N_terminal PF17681.1 KFH41293.1 - 5e-40 138.0 0.0 7.6e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFH41293.1 - 5.5e-24 85.2 0.2 1.2e-23 84.1 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KFH41293.1 - 5e-06 25.2 0.0 1.2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 CutC PF03932.14 KFH41294.1 - 7.6e-25 87.6 0.0 3.1e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 CutC family Questin_oxidase PF14027.6 KFH41295.1 - 5e-87 292.6 0.7 6.1e-87 292.3 0.7 1.0 1 0 0 1 1 1 1 Questin oxidase-like Tricorn_C1 PF14684.6 KFH41295.1 - 0.21 11.7 1.2 1.7 8.8 0.3 2.7 2 1 1 3 3 3 0 Tricorn protease C1 domain WD40 PF00400.32 KFH41296.1 - 6.2e-43 144.0 28.5 1.9e-07 31.7 0.0 13.1 14 0 0 14 14 14 8 WD domain, G-beta repeat Utp12 PF04003.12 KFH41296.1 - 9.3e-24 83.8 0.0 1.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFH41296.1 - 2.4e-22 79.0 0.0 0.0023 18.2 0.0 9.8 4 2 5 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH41296.1 - 1.3e-09 37.5 0.5 2.7 6.9 0.0 7.3 5 3 3 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFH41296.1 - 2.1e-07 31.0 0.4 0.033 14.1 0.1 5.2 5 1 1 6 6 6 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFH41296.1 - 8.6e-05 22.0 0.0 0.26 10.6 0.0 4.0 5 0 0 5 5 5 2 WD40-like domain Nup160 PF11715.8 KFH41296.1 - 0.0012 17.6 3.6 2 7.0 0.0 4.5 3 3 1 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 KFH41296.1 - 0.0015 18.4 0.4 23 5.1 0.1 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFH41296.1 - 0.031 12.8 0.5 9.8 4.6 0.0 3.6 3 2 2 5 5 5 0 Cytochrome D1 heme domain LCCL PF03815.19 KFH41297.1 - 7.5e-20 70.8 0.1 1.3e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF983 PF06170.12 KFH41297.1 - 2.6 8.5 5.0 40 4.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Lactamase_B PF00753.27 KFH41300.1 - 3.7e-17 63.0 1.3 4.5e-11 43.1 0.1 2.2 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KFH41300.1 - 6.1e-17 61.3 0.1 1.2e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KFH41300.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFH41300.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain KaiB PF07689.12 KFH41300.1 - 0.054 13.2 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 KaiB domain Ytp1 PF10355.9 KFH41301.1 - 1.7e-118 394.8 5.8 2.8e-118 394.1 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFH41301.1 - 8.9e-32 109.0 15.9 2.7e-31 107.5 4.4 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF2427) TadE PF07811.12 KFH41301.1 - 0.51 10.7 9.3 2.1 8.7 0.1 4.1 4 0 0 4 4 4 0 TadE-like protein RTA1 PF04479.13 KFH41302.1 - 1e-41 142.9 3.9 1.3e-41 142.5 3.9 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.10 KFH41302.1 - 0.02 13.9 2.6 0.063 12.3 1.6 2.0 1 1 1 2 2 2 0 PalH/RIM21 Rsa3 PF14615.6 KFH41303.1 - 1.2e-18 66.3 0.6 1.5e-18 66.1 0.6 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 adh_short PF00106.25 KFH41304.1 - 3.4e-23 82.1 0.0 2.6e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41304.1 - 4.5e-09 36.2 0.0 3.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH41304.1 - 6.2e-07 29.5 0.1 1e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KFH41305.1 - 4.3e-14 52.6 0.0 5.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFH41305.1 - 9e-14 51.5 0.0 2.5e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFH41305.1 - 2.6e-12 47.0 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFH41305.1 - 8e-09 34.9 0.0 1.6e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFH41305.1 - 2.5e-07 30.4 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFH41305.1 - 5.4e-05 22.7 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KFH41305.1 - 6.2e-05 22.2 0.0 0.0024 17.0 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 KFH41305.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KFH41305.1 - 0.011 15.0 0.1 0.69 9.0 0.1 2.3 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 KFH41305.1 - 0.019 14.9 0.1 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 KR domain EI24 PF07264.11 KFH41306.1 - 5.8e-11 43.0 8.3 2.3e-08 34.5 8.3 2.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 KFH41307.1 - 0.00031 20.8 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SNF2_N PF00176.23 KFH41308.1 - 6.3e-60 202.7 0.0 1.1e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KFH41308.1 - 1.2e-56 191.8 2.1 1.1e-55 188.6 2.4 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KFH41308.1 - 4.7e-16 59.1 0.0 1.6e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41308.1 - 2.8e-10 40.4 0.0 5.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH41308.1 - 3.6e-05 23.6 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFH41308.1 - 0.002 17.4 0.0 0.011 15.0 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFH41308.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PCI PF01399.27 KFH41309.1 - 3.1e-10 40.5 0.0 9.5e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KFH41309.1 - 0.00018 21.0 0.9 0.00039 20.0 0.9 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix TPR_MalT PF17874.1 KFH41309.1 - 0.0034 16.8 0.2 0.0069 15.8 0.2 1.5 1 0 0 1 1 1 1 MalT-like TPR region Bromodomain PF00439.25 KFH41310.1 - 1e-37 128.1 0.2 2.6e-18 65.9 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KFH41310.1 - 5.7e-17 61.7 0.9 1.8e-16 60.1 0.2 2.3 3 0 0 3 3 3 1 BAH domain CDC45 PF02724.14 KFH41310.1 - 3.7e-05 22.2 6.3 5.9e-05 21.6 6.3 1.3 1 0 0 1 1 1 1 CDC45-like protein PGA2 PF07543.12 KFH41310.1 - 1 9.3 8.7 5.4 7.0 8.7 2.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF913 PF06025.12 KFH41310.1 - 2.4 7.0 4.9 0.63 9.0 0.4 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) UCH PF00443.29 KFH41311.1 - 4.6e-48 163.9 2.4 6.1e-48 163.6 2.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH41311.1 - 1.4e-32 113.6 6.5 2.1e-32 113.0 6.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFH41311.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf_C2H2_ZHX PF18387.1 KFH41311.1 - 0.015 15.0 1.3 0.044 13.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF812 PF05667.11 KFH41311.1 - 0.22 10.4 0.2 0.29 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) zf-CCHC_2 PF13696.6 KFH41311.1 - 5 7.1 7.9 22 5.0 0.8 3.4 3 0 0 3 3 3 0 Zinc knuckle OPT PF03169.15 KFH41312.1 - 8.2e-173 576.4 44.0 9.3e-173 576.2 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gaa1 PF04114.14 KFH41313.1 - 4.4e-165 550.5 1.5 5.2e-165 550.2 1.5 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KFH41314.1 - 1.1e-13 51.4 8.6 1.1e-13 51.4 8.6 1.6 2 0 0 2 2 2 1 Rhomboid family OTU PF02338.19 KFH41315.1 - 3.5e-08 34.0 0.0 6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Mito_carr PF00153.27 KFH41316.1 - 9.9e-45 150.4 1.6 1.8e-19 69.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.23 KFH41317.1 - 3.5e-07 30.0 0.1 5.7e-07 29.3 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_11 PF08241.12 KFH41318.1 - 0.00035 21.1 0.0 0.00079 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41318.1 - 0.0034 18.0 0.0 0.0077 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH41318.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFH41318.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KFH41318.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF515 PF04415.12 KFH41318.1 - 9.9 4.4 6.0 25 3.1 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TPR_12 PF13424.6 KFH41320.1 - 5.6e-20 71.4 10.9 4.8e-11 42.8 0.5 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH41320.1 - 2e-15 56.1 17.4 2e-05 24.3 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KFH41320.1 - 4.4e-08 32.6 0.0 1.3e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFH41320.1 - 6.6e-06 26.6 0.8 1.8e-05 25.2 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain TPR_14 PF13428.6 KFH41320.1 - 4e-05 24.1 15.7 0.76 10.8 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 KFH41320.1 - 7.9e-05 23.0 0.0 0.00043 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.17 KFH41320.1 - 0.00012 21.9 19.4 0.11 12.7 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat AAA PF00004.29 KFH41320.1 - 0.00026 21.4 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_8 PF13181.6 KFH41320.1 - 0.00038 20.4 4.9 0.96 9.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH41320.1 - 0.00045 19.7 4.5 0.00045 19.7 4.5 2.3 1 1 1 2 2 2 1 MalT-like TPR region TPR_5 PF12688.7 KFH41320.1 - 0.0022 18.2 5.7 2 8.7 0.3 3.8 2 1 1 3 3 3 2 Tetratrico peptide repeat AAA_33 PF13671.6 KFH41320.1 - 0.0039 17.4 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFH41320.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Abhydrolase_6 PF12697.7 KFH41320.1 - 0.0062 17.2 0.0 0.019 15.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_18 PF13238.6 KFH41320.1 - 0.013 16.1 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFH41320.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFH41320.1 - 0.018 15.0 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF676 PF05057.14 KFH41320.1 - 0.02 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_28 PF13521.6 KFH41320.1 - 0.031 14.5 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFH41320.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KFH41320.1 - 0.065 13.0 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFH41320.1 - 0.11 12.0 0.1 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFH41320.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_1 PF00515.28 KFH41320.1 - 0.25 11.3 0.0 0.25 11.3 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat MIT PF04212.18 KFH41320.1 - 0.43 10.7 3.2 0.94 9.6 0.0 3.2 4 0 0 4 4 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KFH41320.1 - 1.3 9.2 0.0 1.3 9.2 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFH41320.1 - 1.7 8.4 3.3 53 3.6 0.0 4.0 4 0 0 4 4 4 0 TPR repeat SAP PF02037.27 KFH41321.1 - 2.8e-14 52.5 0.2 5.7e-14 51.5 0.2 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KFH41321.1 - 3.3e-05 23.6 3.6 3.3e-05 23.6 3.6 2.4 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KFH41321.1 - 0.041 13.6 0.2 0.13 12.0 0.2 1.9 1 1 0 1 1 1 0 HeH/LEM domain Abhydrolase_6 PF12697.7 KFH41322.1 - 1.7e-18 68.1 8.5 2.4e-18 67.6 8.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH41322.1 - 8.5e-15 54.7 0.4 1.8e-14 53.6 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH41322.1 - 2.8e-14 53.4 0.3 2e-13 50.6 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH41322.1 - 5.3e-05 22.8 0.4 0.043 13.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 KFH41322.1 - 0.0024 18.0 0.3 0.005 17.0 0.3 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KFH41322.1 - 0.042 13.7 0.3 0.11 12.4 0.3 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KFH41322.1 - 0.048 13.4 0.1 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family APH PF01636.23 KFH41323.1 - 2.1e-12 47.5 0.0 5.5e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4530 PF15039.6 KFH41323.1 - 0.014 15.5 0.6 0.029 14.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Pep1_7 PF17232.2 KFH41323.1 - 0.13 12.8 4.1 2.3 8.8 0.4 2.9 3 0 0 3 3 3 0 Elicitor peptide 1-7 Metallophos PF00149.28 KFH41324.1 - 1.1e-14 55.5 0.1 1.8e-14 54.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH41324.1 - 0.0042 17.3 0.0 0.0096 16.1 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Phage_P2_GpE PF06528.12 KFH41324.1 - 0.048 13.2 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Phage P2 GpE Pkinase PF00069.25 KFH41325.1 - 1.1e-42 146.3 0.0 2.6e-42 145.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41325.1 - 6e-28 97.8 0.0 8.8e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH41325.1 - 7.4e-05 21.7 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH41325.1 - 0.21 10.9 0.0 1.1 8.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like UL42 PF17638.2 KFH41325.1 - 3.4 7.7 14.3 8.4 6.4 9.4 2.6 2 0 0 2 2 2 0 HCMV UL42 GCD14 PF08704.10 KFH41327.1 - 1.3e-05 25.0 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Clr5 PF14420.6 KFH41331.1 - 2.6e-23 82.0 0.3 7.7e-23 80.5 0.3 1.9 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_7 PF00840.20 KFH41332.1 - 1e-186 620.9 13.7 1.2e-186 620.7 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zinc-ribbons_6 PF07191.12 KFH41333.1 - 0.5 10.4 17.6 31 4.6 17.6 2.1 1 1 0 1 1 1 0 zinc-ribbons DUF2614 PF11023.8 KFH41333.1 - 0.85 9.7 5.9 0.13 12.3 0.8 1.8 1 1 1 2 2 2 0 Zinc-ribbon containing domain ADH_zinc_N PF00107.26 KFH41334.1 - 6.6e-10 39.1 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH41334.1 - 2.6e-08 35.0 0.1 6e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41334.1 - 0.00015 21.6 0.5 0.011 15.6 0.2 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KFH41335.1 - 4.3e-76 255.8 0.1 8.5e-76 254.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH41335.1 - 2.8e-58 196.8 0.1 1e-57 194.9 0.1 2.1 2 0 0 2 2 1 1 KR domain PS-DH PF14765.6 KFH41335.1 - 3.6e-58 197.2 1.6 6.7e-58 196.3 1.6 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH41335.1 - 5.1e-48 164.2 0.1 1e-47 163.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH41335.1 - 7.1e-37 126.0 0.1 1.9e-36 124.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH41335.1 - 6.4e-21 75.0 0.1 5.9e-20 71.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH41335.1 - 2.2e-16 60.3 0.0 1.3e-13 51.4 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KFH41335.1 - 2.2e-10 40.6 0.0 5.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41335.1 - 6.6e-10 39.6 0.1 5.3e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KFH41335.1 - 7.1e-10 38.7 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KFH41335.1 - 1.6e-09 38.3 0.0 4.9e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KFH41335.1 - 5.4e-08 32.9 1.5 2.8e-07 30.6 1.5 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41335.1 - 4.5e-06 26.5 1.7 1.4e-05 25.0 1.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KFH41335.1 - 7.8e-06 25.8 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH41335.1 - 2.9e-05 23.7 0.1 9.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KFH41335.1 - 0.0003 20.2 0.6 0.00066 19.1 0.6 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KFH41335.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFH41335.1 - 0.0006 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KFH41335.1 - 0.0018 18.1 0.1 0.007 16.2 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KFH41335.1 - 0.011 15.5 0.1 0.12 12.1 0.1 2.2 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis NodS PF05401.11 KFH41335.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) p450 PF00067.22 KFH41336.1 - 1.2e-32 113.3 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NIF PF03031.18 KFH41337.1 - 3.8e-21 75.5 0.0 4.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_SAK_2 PF18143.1 KFH41337.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Ribosomal_S9 PF00380.19 KFH41338.1 - 6.1e-41 139.7 0.6 1.1e-40 138.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ABC1 PF03109.16 KFH41339.1 - 3.8e-30 104.5 0.0 6.6e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family FCD PF07729.12 KFH41339.1 - 0.11 12.9 0.1 0.36 11.3 0.1 1.9 1 1 0 1 1 1 0 FCD domain Pkinase PF00069.25 KFH41339.1 - 0.21 10.9 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein kinase domain EPL1 PF10513.9 KFH41340.1 - 1.1e-20 74.7 0.2 2.7e-20 73.3 0.2 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like TIP39 PF14980.6 KFH41340.1 - 0.1 12.5 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 TIP39 peptide PPP5 PF08321.12 KFH41341.1 - 8e-32 109.4 0.7 1.4e-31 108.6 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KFH41341.1 - 1.8e-31 110.3 0.1 3.1e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KFH41341.1 - 1.4e-18 65.8 2.5 3.9e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH41341.1 - 4e-15 54.6 1.4 0.00067 19.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH41341.1 - 5.2e-13 48.4 3.8 3.3e-07 29.9 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KFH41341.1 - 2.7e-09 36.5 1.1 0.045 14.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFH41341.1 - 3.4e-06 27.1 0.7 0.32 11.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH41341.1 - 9.6e-06 26.0 0.9 0.004 17.6 1.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH41341.1 - 7.5e-05 22.8 0.1 0.00088 19.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH41341.1 - 0.0017 19.0 0.4 6.6 7.8 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH41341.1 - 0.004 17.8 1.4 0.23 12.1 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH41341.1 - 0.0044 17.6 0.4 0.6 10.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFH41341.1 - 0.0065 16.7 0.3 1.4 9.2 0.2 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KFH41341.1 - 0.021 14.9 0.5 0.064 13.3 0.1 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KFH41341.1 - 0.054 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFH41341.1 - 0.17 11.4 0.1 16 5.1 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR Spt4 PF06093.13 KFH41342.1 - 5.4e-32 109.7 0.2 6.7e-32 109.4 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF572 PF04502.13 KFH41343.1 - 8.2e-65 219.6 7.1 9.8e-65 219.3 7.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 KFH41343.1 - 0.12 12.4 1.0 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DNA_RNApol_7kD PF03604.13 KFH41343.1 - 0.63 9.8 3.4 17 5.2 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Acetyltransf_2 PF00797.17 KFH41344.1 - 1.2e-23 84.2 0.0 5.4e-22 78.7 0.0 2.1 1 1 0 1 1 1 1 N-acetyltransferase p450 PF00067.22 KFH41345.1 - 2e-37 129.1 0.0 1.3e-22 80.2 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 Trp_DMAT PF11991.8 KFH41346.1 - 8.5e-89 298.5 0.0 1.5e-87 294.4 0.0 1.9 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Peptidase_M15_4 PF13539.6 KFH41346.1 - 0.093 13.3 0.3 0.25 11.9 0.3 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Aldo_ket_red PF00248.21 KFH41347.1 - 1.5e-36 126.1 0.0 4.2e-35 121.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RRP36 PF06102.12 KFH41348.1 - 1.8e-52 177.7 25.7 1.8e-52 177.7 25.7 1.7 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Es2 PF09751.9 KFH41349.1 - 2e-112 377.1 1.0 2e-112 377.1 1.0 1.7 2 0 0 2 2 2 1 Nuclear protein Es2 EF1G PF00647.19 KFH41350.1 - 5.1e-42 142.3 0.1 9.1e-42 141.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KFH41350.1 - 1.5e-14 54.0 0.0 3.4e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH41350.1 - 1.6e-10 40.9 0.1 6.8e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFH41350.1 - 9.6e-07 29.1 0.0 3.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFH41350.1 - 3.6e-05 23.9 0.0 9.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEC-1_N PF04625.13 KFH41350.1 - 0.29 10.1 7.0 0.43 9.5 7.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4799 PF16056.5 KFH41350.1 - 1.2 8.2 6.5 35 3.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4799) EF-hand_1 PF00036.32 KFH41352.1 - 4.2e-26 88.5 14.3 1.3e-07 30.6 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFH41352.1 - 7.1e-22 77.6 8.9 1e-13 51.5 1.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFH41352.1 - 1.3e-19 68.4 8.1 0.00015 21.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFH41352.1 - 6.4e-18 63.4 12.7 6.2e-07 28.6 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFH41352.1 - 3.6e-14 52.4 12.7 6.4e-05 22.7 0.6 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KFH41352.1 - 8.3e-07 28.9 8.2 0.0015 18.5 0.3 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFH41352.1 - 5.9e-06 26.6 0.1 0.0062 16.8 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFH41352.1 - 0.01 16.0 1.0 0.042 14.0 0.5 2.3 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 KFH41352.1 - 0.03 14.7 0.1 2.5 8.5 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Anillin PF08174.11 KFH41352.1 - 0.072 13.5 0.0 0.64 10.4 0.0 2.0 1 1 1 2 2 2 0 Cell division protein anillin Kin17_mid PF10357.9 KFH41353.1 - 8.6e-53 177.6 0.9 2e-52 176.4 0.9 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KFH41353.1 - 0.0049 17.1 2.9 0.0049 17.1 2.9 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFH41353.1 - 0.022 15.1 2.0 0.091 13.1 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Methyltransf_12 PF08242.12 KFH41353.1 - 0.18 12.6 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-met PF12874.7 KFH41353.1 - 1.7 9.2 10.2 0.097 13.1 4.7 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Med5 PF08689.10 KFH41355.1 - 6.2e-78 262.8 0.0 2.3e-76 257.6 0.0 3.0 1 1 0 2 2 2 1 Mediator complex subunit Med5 DED PF01335.21 KFH41355.1 - 0.2 12.0 1.2 4.2 7.7 0.4 3.2 3 0 0 3 3 3 0 Death effector domain SUIM_assoc PF16619.5 KFH41355.1 - 1.8 8.7 10.3 0.48 10.5 6.7 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AMP-binding_C PF13193.6 KFH41356.1 - 6.2e-06 27.1 0.1 0.0014 19.6 0.0 2.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Amidoligase_2 PF12224.8 KFH41357.1 - 3.3e-13 49.9 0.0 1.3e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Putative amidoligase enzyme Brix PF04427.18 KFH41358.1 - 1e-43 149.7 0.1 1.4e-43 149.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain TPR_1 PF00515.28 KFH41359.1 - 9.4e-23 79.0 7.0 2e-07 30.5 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH41359.1 - 1.4e-22 77.9 5.5 6.2e-07 29.1 0.1 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH41359.1 - 2.7e-19 68.6 5.4 3.9e-08 32.9 0.1 5.1 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 KFH41359.1 - 3e-16 58.7 11.1 1.1e-05 25.8 0.1 6.1 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH41359.1 - 3.6e-16 59.5 7.0 2.2e-05 25.0 2.9 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFH41359.1 - 4e-15 54.7 1.0 3e-06 27.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH41359.1 - 2.3e-14 53.6 7.5 0.0023 18.4 0.5 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFH41359.1 - 1.8e-12 46.7 4.9 0.062 13.7 0.1 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFH41359.1 - 4.5e-12 45.1 3.1 0.0054 16.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFH41359.1 - 2.8e-10 40.3 6.9 0.0039 17.4 1.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFH41359.1 - 7.4e-10 38.8 0.8 0.0026 17.9 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH41359.1 - 6.3e-09 35.9 2.2 1.3 9.8 0.2 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFH41359.1 - 2.7e-07 30.8 2.3 0.12 12.7 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFH41359.1 - 5.9e-06 25.7 0.5 0.045 13.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH41359.1 - 0.002 18.3 4.4 0.66 10.2 0.7 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFH41359.1 - 0.0094 15.9 0.1 9.3 6.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KFH41359.1 - 0.051 13.7 1.0 33 4.7 0.0 3.8 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFH41359.1 - 0.078 12.9 0.4 0.078 12.9 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 KFH41359.1 - 0.12 12.2 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Cys_Met_Meta_PP PF01053.20 KFH41360.1 - 1.7e-138 461.3 0.1 2e-138 461.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFH41360.1 - 1.2e-07 31.2 0.1 2.1e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFH41360.1 - 1.1e-06 27.9 1.5 1.4e-06 27.5 0.7 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFH41360.1 - 5.9e-06 25.8 0.6 1e-05 25.0 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KFH41360.1 - 0.014 13.9 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KFH41360.1 - 0.035 13.4 0.1 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase 2-Hacid_dh PF00389.30 KFH41360.1 - 0.089 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.18 KFH41362.1 - 2.9e-08 33.7 13.4 4.7e-08 33.0 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3970 PF13113.6 KFH41362.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Fungal_trans PF04082.18 KFH41362.1 - 0.089 11.8 0.1 0.22 10.5 0.1 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain 6PGD PF00393.19 KFH41363.1 - 9.2e-86 287.8 0.0 1.1e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFH41363.1 - 6.4e-30 104.4 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFH41363.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFH41363.1 - 0.00072 19.2 0.0 0.0019 17.8 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFH41363.1 - 0.0031 17.5 0.0 0.0088 16.0 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KFH41363.1 - 0.0041 16.7 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KFH41363.1 - 0.0056 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 KFH41363.1 - 0.033 14.9 0.0 0.18 12.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KFH41363.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 KFH41363.1 - 0.11 12.8 0.3 2.6 8.3 0.0 2.7 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SET PF00856.28 KFH41364.1 - 4.2e-09 37.0 0.0 1.5e-08 35.2 0.0 2.0 2 2 0 2 2 2 1 SET domain zf-MYND PF01753.18 KFH41364.1 - 7.1e-08 32.4 14.3 7.1e-08 32.4 14.3 2.4 2 0 0 2 2 2 1 MYND finger Cadherin_C_2 PF16492.5 KFH41365.1 - 0.026 15.2 0.1 0.07 13.9 0.1 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal SKG6 PF08693.10 KFH41365.1 - 0.26 10.7 2.7 0.47 9.9 2.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short_C2 PF13561.6 KFH41367.1 - 3.4e-55 187.2 2.2 4.2e-55 186.9 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH41367.1 - 9.4e-50 168.8 0.4 1.3e-49 168.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH41367.1 - 1.6e-08 34.7 0.5 3.4e-08 33.6 0.3 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFH41367.1 - 0.01 15.2 0.2 0.022 14.1 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KFH41367.1 - 0.087 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2620 PF10941.8 KFH41367.1 - 0.14 12.3 0.8 0.26 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 PGA2 PF07543.12 KFH41368.1 - 0.47 10.4 1.8 0.71 9.8 1.8 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 KFH41368.1 - 1.1 7.3 6.3 1.4 6.9 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 KFH41368.1 - 4.3 5.3 9.5 11 4.0 9.1 1.6 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Spt5_N PF11942.8 KFH41368.1 - 6 7.9 10.5 10 7.2 10.5 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal adh_short PF00106.25 KFH41369.1 - 1.7e-25 89.6 0.0 2.2e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41369.1 - 5.5e-18 65.4 0.0 1.2e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH41369.1 - 2.5e-07 30.8 0.1 4.2e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH41369.1 - 0.00076 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFH41369.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFH41369.1 - 0.027 13.7 0.4 0.067 12.4 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFH41369.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 KFH41370.1 - 1.4e-07 31.5 7.8 2.3e-07 30.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH41370.1 - 3.8e-05 22.7 0.2 5.9e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.26 KFH41371.1 - 8.9e-11 41.6 0.8 2.3e-10 40.3 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain F-box PF00646.33 KFH41372.1 - 0.048 13.6 0.3 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 F-box domain Glutaredoxin PF00462.24 KFH41373.1 - 1.7e-15 57.0 0.1 4.3e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 KFH41373.1 - 0.071 13.5 0.0 0.22 12.0 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain ADH_zinc_N PF00107.26 KFH41374.1 - 2.7e-07 30.6 0.0 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41374.1 - 0.00076 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH41374.1 - 0.0011 20.0 0.1 0.0032 18.5 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AP_endonuc_2 PF01261.24 KFH41375.1 - 4e-33 114.7 0.0 5.1e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel WEMBL PF05701.11 KFH41376.1 - 0.0001 21.2 10.7 0.0001 21.2 10.7 1.4 2 0 0 2 2 1 1 Weak chloroplast movement under blue light AAA_13 PF13166.6 KFH41376.1 - 0.00011 21.1 5.2 0.00016 20.5 5.2 1.1 1 0 0 1 1 1 1 AAA domain ZapB PF06005.12 KFH41376.1 - 0.0003 21.2 15.6 0.33 11.4 0.2 4.4 3 1 1 4 4 4 1 Cell division protein ZapB GAS PF13851.6 KFH41376.1 - 0.00071 19.0 13.6 0.0037 16.6 1.9 2.7 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 KFH41376.1 - 0.00083 17.3 14.7 0.0011 16.8 14.7 1.1 1 0 0 1 1 1 1 Myosin tail Fez1 PF06818.15 KFH41376.1 - 0.0027 18.2 15.7 0.043 14.3 3.8 2.4 1 1 1 2 2 2 2 Fez1 TolA_bind_tri PF16331.5 KFH41376.1 - 0.0069 16.4 19.8 0.011 15.8 3.4 5.1 3 1 1 5 5 5 1 TolA binding protein trimerisation Spc7 PF08317.11 KFH41376.1 - 0.0078 15.1 19.4 0.028 13.3 5.0 2.7 2 1 1 3 3 3 2 Spc7 kinetochore protein Filament PF00038.21 KFH41376.1 - 0.008 15.8 17.8 0.025 14.1 10.0 2.6 2 1 1 3 3 3 1 Intermediate filament protein Laminin_II PF06009.12 KFH41376.1 - 0.0097 15.9 12.5 0.64 10.0 3.1 3.3 2 1 0 3 3 3 2 Laminin Domain II T6PP_N PF18572.1 KFH41376.1 - 0.011 15.6 0.7 0.011 15.6 0.7 2.4 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain EzrA PF06160.12 KFH41376.1 - 0.014 13.7 10.1 0.2 9.8 4.1 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA MRP-S26 PF14943.6 KFH41376.1 - 0.02 14.8 4.0 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 YabA PF06156.13 KFH41376.1 - 0.027 15.1 9.0 0.2 12.3 2.4 3.3 2 1 1 3 3 2 0 Initiation control protein YabA ATG16 PF08614.11 KFH41376.1 - 0.033 14.4 23.1 0.21 11.8 3.7 2.9 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 KFH41376.1 - 0.038 13.2 5.6 1.5 7.9 0.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein LMP PF04778.12 KFH41376.1 - 0.049 13.6 5.2 0.097 12.6 3.4 2.0 1 1 1 2 2 2 0 LMP repeated region TPR_MLP1_2 PF07926.12 KFH41376.1 - 0.051 13.6 20.9 0.09 12.8 5.1 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 KFH41376.1 - 0.057 14.0 20.3 0.15 12.7 1.6 3.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Occludin_ELL PF07303.13 KFH41376.1 - 0.058 14.1 7.0 20 6.0 0.0 4.1 1 1 3 4 4 4 0 Occludin homology domain Streptin-Immun PF11083.8 KFH41376.1 - 0.061 13.7 0.2 0.19 12.2 0.2 1.8 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Uso1_p115_C PF04871.13 KFH41376.1 - 0.069 13.5 22.3 0.033 14.6 3.3 4.0 2 1 2 4 4 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 KFH41376.1 - 0.075 12.5 17.8 0.039 13.4 13.8 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 KFH41376.1 - 0.08 12.4 13.0 0.13 11.7 11.2 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DHR-2 PF06920.13 KFH41376.1 - 0.085 11.5 1.1 0.12 10.9 1.1 1.2 1 0 0 1 1 1 0 Dock homology region 2 Snapin_Pallidin PF14712.6 KFH41376.1 - 0.086 13.3 18.0 0.12 12.8 0.5 4.0 2 1 1 4 4 4 0 Snapin/Pallidin Spectrin PF00435.21 KFH41376.1 - 0.095 13.2 8.5 0.25 11.8 0.2 3.4 3 1 0 3 3 3 0 Spectrin repeat APG6_N PF17675.1 KFH41376.1 - 0.095 13.2 18.9 1.4 9.4 3.9 2.6 2 1 1 3 3 2 0 Apg6 coiled-coil region MAD PF05557.13 KFH41376.1 - 0.098 11.0 17.6 0.23 9.8 13.4 2.3 1 1 0 2 2 2 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 KFH41376.1 - 0.13 12.5 18.9 1.1 9.4 9.5 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding SPATA1_C PF15743.5 KFH41376.1 - 0.14 12.2 12.6 0.31 11.1 6.4 2.5 3 0 0 3 3 2 0 Spermatogenesis-associated C-terminus Sec8_exocyst PF04048.14 KFH41376.1 - 0.19 11.6 4.1 3.7 7.4 3.2 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3829 PF12889.7 KFH41376.1 - 0.22 11.0 1.9 0.43 10.0 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF4407 PF14362.6 KFH41376.1 - 0.23 10.8 13.1 0.32 10.3 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 KFH41376.1 - 0.25 11.4 16.9 0.49 10.5 7.1 2.7 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 KFH41376.1 - 0.27 11.3 18.3 2.9 7.9 3.5 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.9 KFH41376.1 - 0.31 9.9 9.7 0.77 8.7 4.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FAP206 PF12018.8 KFH41376.1 - 0.36 10.3 4.1 0.43 10.1 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF948 PF06103.11 KFH41376.1 - 0.37 11.1 4.2 18 5.7 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4763 PF15960.5 KFH41376.1 - 0.42 9.9 14.6 3.1 7.0 4.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) Jnk-SapK_ap_N PF09744.9 KFH41376.1 - 0.46 10.7 17.4 9.7 6.4 9.2 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 KFH41376.1 - 0.47 7.9 16.1 0.29 8.6 13.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) STAT_alpha PF01017.20 KFH41376.1 - 0.47 10.3 8.6 0.23 11.3 4.5 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain LPP PF04728.13 KFH41376.1 - 0.48 10.9 7.5 29 5.2 0.4 4.4 3 1 0 4 4 3 0 Lipoprotein leucine-zipper Leu_zip PF15294.6 KFH41376.1 - 0.58 9.6 11.4 0.65 9.5 2.2 2.4 1 1 1 2 2 2 0 Leucine zipper GIT_CC PF16559.5 KFH41376.1 - 0.66 9.9 5.5 4 7.4 0.5 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor WES_acyltransf PF03007.16 KFH41376.1 - 0.74 9.5 4.9 0.33 10.7 2.1 1.9 2 1 0 2 2 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain MscS_porin PF12795.7 KFH41376.1 - 0.8 9.2 25.2 9 5.8 19.1 3.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HAP1_N PF04849.13 KFH41376.1 - 0.83 8.8 16.1 0.46 9.6 12.7 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region CENP-H PF05837.12 KFH41376.1 - 0.9 10.0 19.6 0.28 11.6 6.3 3.2 2 1 1 3 3 2 0 Centromere protein H (CENP-H) Nup54 PF13874.6 KFH41376.1 - 0.96 9.6 14.3 0.053 13.6 7.6 2.3 2 1 0 3 3 1 0 Nucleoporin complex subunit 54 Tup_N PF08581.10 KFH41376.1 - 1 9.7 9.8 4.3 7.7 1.8 3.5 2 1 2 4 4 3 0 Tup N-terminal AIP3 PF03915.13 KFH41376.1 - 1.2 8.1 11.3 3.7 6.5 10.8 1.9 1 1 0 1 1 1 0 Actin interacting protein 3 Atg14 PF10186.9 KFH41376.1 - 1.4 7.9 14.4 0.1 11.7 2.8 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 KFH41376.1 - 1.5 7.6 13.9 1.8 7.4 6.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) LMBR1 PF04791.16 KFH41376.1 - 1.7 7.5 2.4 2.3 7.0 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KFH41376.1 - 1.9 8.6 12.8 0.54 10.4 4.3 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.19 KFH41376.1 - 2.1 8.1 17.6 4 7.2 1.1 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DivIC PF04977.15 KFH41376.1 - 2.1 8.2 17.8 15 5.4 0.3 5.0 4 1 1 5 5 5 0 Septum formation initiator UPF0242 PF06785.11 KFH41376.1 - 2.3 8.3 14.9 4 7.5 4.8 2.6 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 KFH41376.1 - 2.5 8.2 11.3 5.5 7.1 2.7 3.8 2 1 2 4 4 3 0 FlxA-like protein DUF1664 PF07889.12 KFH41376.1 - 2.5 8.1 9.7 7.2 6.7 0.8 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFH41376.1 - 2.5 8.4 12.4 9.7 6.5 0.0 3.8 2 1 1 4 4 3 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 KFH41376.1 - 2.7 7.5 13.7 23 4.4 13.7 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 KFH41376.1 - 3.4 7.3 13.6 0.49 10.1 4.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF745) Lectin_N PF03954.14 KFH41376.1 - 3.6 7.3 7.8 1.5 8.6 0.9 3.2 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain LXG PF04740.12 KFH41376.1 - 5.3 6.7 10.8 14 5.3 7.4 2.8 2 1 0 2 2 1 0 LXG domain of WXG superfamily OmpH PF03938.14 KFH41376.1 - 5.6 7.3 10.2 9.2e+02 0.1 10.2 2.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AATF-Che1 PF13339.6 KFH41376.1 - 6.3 7.5 10.8 12 6.6 1.2 2.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor NYD-SP28 PF14772.6 KFH41376.1 - 7.6 6.7 9.5 8.1 6.6 0.2 2.9 2 1 0 2 2 2 0 Sperm tail Bacillus_HBL PF05791.11 KFH41376.1 - 7.7 6.3 6.7 22 4.8 0.4 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.9 KFH41376.1 - 7.8 6.9 12.0 21 5.5 0.4 4.2 2 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 KFH41376.1 - 7.8 6.8 11.3 51 4.2 0.1 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Phage_GPO PF05929.11 KFH41376.1 - 9.1 5.8 12.8 5.2 6.6 0.8 2.5 2 1 1 3 3 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COG2 PF06148.11 KFH41376.1 - 9.1 6.4 13.7 1.5 8.9 0.8 3.1 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rootletin PF15035.6 KFH41376.1 - 9.2 6.2 15.7 61 3.6 15.6 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SIL1 PF16782.5 KFH41378.1 - 1.4e-07 31.1 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 RNase_T PF00929.24 KFH41379.1 - 4.3e-09 37.1 0.0 7.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Methyltransf_23 PF13489.6 KFH41380.1 - 3.1e-17 62.9 0.0 4.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41380.1 - 3.8e-05 24.3 0.0 0.063 14.0 0.0 3.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41380.1 - 0.00034 21.3 0.0 0.0027 18.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH41380.1 - 0.0006 20.4 0.0 0.01 16.4 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH41380.1 - 0.016 15.0 0.0 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFH41380.1 - 0.043 13.2 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_60s PF00428.19 KFH41380.1 - 3.6 8.3 11.4 3.4 8.3 5.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 KFH41380.1 - 9.5 6.8 11.6 2.8 8.5 4.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SDF PF00375.18 KFH41381.1 - 1e-89 301.3 34.6 1.2e-89 301.0 34.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FCH PF00611.23 KFH41382.1 - 1.1e-17 64.0 0.2 3.6e-17 62.4 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFH41382.1 - 4e-12 45.6 0.0 7.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFH41382.1 - 5.5e-12 45.2 0.0 4.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFH41382.1 - 4.2e-11 42.5 0.5 7.9e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain ApoLp-III PF07464.11 KFH41382.1 - 0.63 10.1 8.0 0.049 13.7 2.0 2.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PhzC-PhzF PF02567.16 KFH41383.1 - 1.8e-34 119.5 0.1 1.6e-33 116.4 0.1 2.0 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Homeobox_KN PF05920.11 KFH41383.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Pkinase PF00069.25 KFH41384.1 - 6.8e-69 232.2 0.0 9.5e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41384.1 - 5.5e-32 111.1 0.0 6.8e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH41384.1 - 0.00051 19.1 0.1 0.021 13.8 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFH41384.1 - 0.011 15.1 0.1 0.018 14.3 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFH41384.1 - 0.022 14.1 0.1 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH41384.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFH41384.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RCC1 PF00415.18 KFH41385.1 - 1.1e-23 83.6 1.0 7.3e-07 29.7 0.4 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFH41385.1 - 9.2e-12 45.2 0.0 1.9e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KFH41385.1 - 4.6e-08 33.5 0.1 3.4e-07 30.7 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KFH41385.1 - 8.4e-08 31.8 0.4 8.4e-08 31.8 0.4 4.8 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KFH41385.1 - 0.0019 18.7 0.0 0.005 17.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH41385.1 - 0.0037 17.6 0.0 5.6 7.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFH41385.1 - 0.17 12.3 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) ATG13 PF10033.9 KFH41387.1 - 1.1e-71 241.3 0.0 1.8e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 KFH41388.1 - 1.6e-37 128.5 0.2 3.9e-37 127.2 0.2 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KFH41388.1 - 1.4e-16 59.8 0.3 3.8e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFH41388.1 - 2.1e-15 56.3 0.1 4.8e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH41388.1 - 2.4e-13 49.5 0.0 4.8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KFH41388.1 - 2e-10 40.8 3.1 2.3e-10 40.6 1.5 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KFH41388.1 - 0.007 16.2 4.6 0.016 15.1 4.6 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4598 PF15370.6 KFH41388.1 - 0.008 16.6 0.9 0.018 15.5 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DUF3361 PF11841.8 KFH41388.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) CRM1_C PF08767.11 KFH41388.1 - 0.19 10.9 0.4 16 4.5 0.0 2.1 2 0 0 2 2 2 0 CRM1 C terminal E1-E2_ATPase PF00122.20 KFH41389.1 - 1.9e-51 174.1 0.4 5.6e-51 172.6 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFH41389.1 - 8.8e-36 124.2 0.4 1.9e-35 123.1 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFH41389.1 - 1.9e-25 89.1 2.8 1.6e-13 50.9 0.2 3.9 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFH41389.1 - 2.5e-06 27.4 0.6 8.3e-06 25.7 0.4 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KFH41389.1 - 0.049 13.7 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Importin 13 repeat HAD PF12710.7 KFH41389.1 - 0.099 13.0 0.0 0.46 10.9 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIF_alpha PF05793.12 KFH41390.1 - 3.3 6.2 9.0 4.9 5.6 9.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0029 PF01205.19 KFH41391.1 - 1.2e-26 93.1 0.0 2.5e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD_binding_1 PF00667.20 KFH41392.1 - 2e-66 223.7 0.0 3.5e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFH41392.1 - 1.3e-10 41.8 0.0 8.4e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 KFH41392.1 - 3.1e-08 33.9 0.3 8.9e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KFH41392.1 - 3.5e-07 30.5 0.2 1e-06 29.0 0.2 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KFH41392.1 - 0.00035 20.4 0.4 0.00086 19.2 0.4 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Not1 PF04054.15 KFH41393.1 - 4.6e-106 354.9 0.0 9.5e-106 353.8 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KFH41393.1 - 9.4e-92 306.5 0.3 1.7e-91 305.6 0.3 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KFH41393.1 - 4.3e-47 159.7 0.7 4.3e-47 159.7 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KFH41393.1 - 1.5e-41 141.6 0.0 1.3e-40 138.6 0.0 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KFH41393.1 - 3e-38 131.2 0.2 9.2e-38 129.7 0.2 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CSTF2_hinge PF14327.6 KFH41393.1 - 0.04 14.4 0.0 0.21 12.1 0.0 2.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Cyclin_N PF00134.23 KFH41394.1 - 2.4e-16 59.6 0.0 3.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFH41394.1 - 5.3e-09 36.6 0.6 2.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin LdpA_C PF12617.8 KFH41394.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal SNF2_N PF00176.23 KFH41396.1 - 2.8e-66 223.6 4.7 3.8e-64 216.6 4.7 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41396.1 - 2.8e-17 63.1 0.0 8.4e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41396.1 - 3.8e-06 27.0 0.0 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH41396.1 - 0.00018 21.4 0.0 0.00054 19.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Tex_N PF09371.10 KFH41396.1 - 0.017 14.8 0.6 0.05 13.3 0.6 1.7 1 0 0 1 1 1 0 Tex-like protein N-terminal domain HDA2-3 PF11496.8 KFH41396.1 - 0.052 12.7 0.0 1.6 7.9 0.1 2.9 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DZR PF12773.7 KFH41396.1 - 0.26 11.3 1.3 0.57 10.3 1.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KFH41396.1 - 0.75 9.8 3.6 0.86 9.6 2.1 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain AAA PF00004.29 KFH41397.1 - 1.1e-37 129.4 0.0 1.9e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH41397.1 - 4.3e-10 39.2 0.0 9.6e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFH41397.1 - 1.2e-06 28.8 0.5 0.0016 18.7 0.0 3.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KFH41397.1 - 1.2e-05 25.1 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFH41397.1 - 2.7e-05 24.2 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFH41397.1 - 4.9e-05 23.4 0.1 0.00054 20.0 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFH41397.1 - 9.4e-05 22.9 1.4 0.0033 17.8 0.0 2.9 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KFH41397.1 - 9.5e-05 22.6 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 KFH41397.1 - 0.00065 19.2 0.1 0.95 8.8 0.0 3.0 2 1 0 3 3 3 2 Bacterial TniB protein IstB_IS21 PF01695.17 KFH41397.1 - 0.00077 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFH41397.1 - 0.002 18.3 0.8 0.0059 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFH41397.1 - 0.0021 17.5 0.1 0.0046 16.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFH41397.1 - 0.0058 17.2 0.1 0.035 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KFH41397.1 - 0.0099 16.0 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KFH41397.1 - 0.014 15.0 0.6 0.13 11.8 0.1 2.5 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KFH41397.1 - 0.014 15.1 0.0 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KFH41397.1 - 0.018 15.0 0.0 0.06 13.3 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KFH41397.1 - 0.022 15.1 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KFH41397.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DUF815 PF05673.13 KFH41397.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KFH41397.1 - 0.037 14.3 0.4 0.1 12.8 0.0 2.0 3 0 0 3 3 1 0 AAA domain ABC_tran PF00005.27 KFH41397.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KFH41397.1 - 0.062 12.6 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KFH41397.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFH41397.1 - 0.079 12.9 0.0 0.62 9.9 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KFH41397.1 - 0.085 12.0 0.1 0.18 10.9 0.0 1.5 1 1 1 2 2 2 0 TIP49 P-loop domain NB-ARC PF00931.22 KFH41397.1 - 0.11 11.6 0.0 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KFH41397.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFH41397.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Oxidored_nitro PF00148.19 KFH41397.1 - 0.17 10.6 0.0 2 7.1 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Guanylate_kin PF00625.21 KFH41397.1 - 0.19 11.4 0.1 1.8 8.2 0.0 2.4 2 1 1 3 3 3 0 Guanylate kinase Viral_helicase1 PF01443.18 KFH41397.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pyr_redox_2 PF07992.14 KFH41398.1 - 9.1e-11 41.5 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH41398.1 - 0.019 15.2 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH41398.1 - 0.2 10.9 0.0 0.71 9.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KFH41398.1 - 0.21 10.2 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein PGAP1 PF07819.13 KFH41399.1 - 3.5e-94 314.9 0.1 5.4e-94 314.2 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFH41399.1 - 6.2e-06 27.0 0.2 2.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH41399.1 - 0.0022 17.3 0.0 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH41399.1 - 0.0075 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KFH41399.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KFH41399.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KFH41399.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 KFH41399.1 - 0.098 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KFH41399.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase MutL_C PF08676.11 KFH41400.1 - 1.1e-21 77.2 0.1 2.3e-21 76.1 0.1 1.6 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFH41400.1 - 8.3e-19 67.4 0.0 3.5e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFH41400.1 - 1.9e-12 47.2 0.1 5e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFH41400.1 - 5.9e-07 30.0 0.1 1.5e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SDA1 PF05285.12 KFH41400.1 - 0.0017 17.9 10.4 0.0017 17.9 10.4 1.7 2 0 0 2 2 2 1 SDA1 CAP_N PF01213.19 KFH41401.1 - 8.7e-121 403.3 0.3 8.7e-121 403.3 0.3 1.5 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFH41401.1 - 3e-57 192.6 3.1 4.1e-57 192.2 3.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.19 KFH41401.1 - 4.8 7.8 7.4 11 6.6 0.3 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein DEC-1_N PF04625.13 KFH41401.1 - 8.3 5.3 25.4 6 5.8 9.3 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region SWIRM PF04433.17 KFH41402.1 - 5.7e-32 109.9 0.1 1.2e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KFH41402.1 - 1.4e-31 108.3 1.5 2.6e-31 107.4 1.5 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KFH41402.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH41402.1 - 2.4e-05 24.5 0.3 5e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KFH41402.1 - 0.0045 16.8 5.6 0.0095 15.7 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SANT_DAMP1_like PF16282.5 KFH41402.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF3439 PF11921.8 KFH41402.1 - 0.21 11.6 5.3 0.25 11.3 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ATP_synt_H PF05493.13 KFH41403.1 - 6.9e-08 32.8 0.1 7.4e-08 32.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Fungal_trans PF04082.18 KFH41404.1 - 2.8e-36 124.9 0.0 5.8e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41404.1 - 0.0003 20.8 1.1 0.00051 20.1 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD_3 PF13922.6 KFH41404.1 - 0.11 12.9 6.0 0.37 11.2 6.0 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Roughex PF06020.11 KFH41404.1 - 2.3 7.3 5.6 3.8 6.5 5.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Arv1 PF04161.13 KFH41405.1 - 3.2e-77 259.4 0.0 3.8e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ETF PF01012.21 KFH41406.1 - 6.4e-42 143.5 1.9 1.2e-41 142.6 1.9 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFH41406.1 - 8.3e-34 115.5 0.2 1.8e-33 114.4 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain MFS_1 PF07690.16 KFH41407.1 - 4e-21 75.3 26.4 5e-18 65.1 25.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KFH41407.1 - 1.2e-11 44.6 1.2 1.2e-11 44.6 1.2 2.3 2 0 0 2 2 2 1 Nodulin-like DUF2530 PF10745.9 KFH41407.1 - 2.4 8.5 5.3 0.95 9.7 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF2207 PF09972.9 KFH41407.1 - 5 5.8 6.1 2.8 6.6 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PfkB PF00294.24 KFH41409.1 - 1.8e-13 50.5 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Carn_acyltransf PF00755.20 KFH41410.1 - 3.2e-208 693.1 0.0 3.7e-208 692.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cys_Met_Meta_PP PF01053.20 KFH41411.1 - 6.9e-139 462.6 0.1 7.9e-139 462.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFH41411.1 - 5.5e-06 25.8 0.0 1.4e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFH41411.1 - 2.8e-05 23.6 0.2 8.5e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KFH41411.1 - 3.7e-05 22.4 0.2 0.00011 20.9 0.2 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KFH41411.1 - 3.8e-05 22.8 0.2 9e-05 21.6 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFH41411.1 - 0.025 13.9 0.6 0.056 12.7 0.6 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase HNH_repeat PF18780.1 KFH41411.1 - 0.24 11.2 0.4 0.48 10.3 0.4 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat 2_5_RNA_ligase2 PF13563.6 KFH41412.1 - 4e-33 114.5 0.8 5.8e-31 107.5 0.3 2.4 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KFH41412.1 - 2.3e-18 66.7 1.6 6e-18 65.3 1.6 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 KFH41412.1 - 7.4e-11 41.5 0.0 1.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 KFH41412.1 - 1.7e-08 34.3 0.2 4.2e-08 33.0 0.2 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nrap_D2 PF17403.2 KFH41412.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain YL1 PF05764.13 KFH41412.1 - 0.16 12.1 2.0 0.25 11.4 2.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Exo70 PF03081.15 KFH41413.1 - 6.3e-92 308.5 0.1 9.7e-92 307.9 0.1 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF2972 PF11186.8 KFH41413.1 - 0.026 14.4 0.1 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Baculo_PEP_C PF04513.12 KFH41413.1 - 0.037 14.1 2.2 0.96 9.5 0.1 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KFH41413.1 - 0.052 13.4 4.0 0.18 11.6 0.1 3.1 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain K-box PF01486.17 KFH41413.1 - 0.096 12.9 1.8 3.2 8.0 0.1 3.4 3 0 0 3 3 3 0 K-box region DUF2203 PF09969.9 KFH41413.1 - 1.1 10.0 2.7 4.3 8.1 0.1 3.0 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) PigN PF04987.14 KFH41414.1 - 6.3e-159 529.7 32.2 8e-159 529.3 32.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KFH41414.1 - 2.8e-09 37.0 3.7 1.4e-07 31.4 3.7 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFH41414.1 - 1.1e-06 28.3 0.2 4.9e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 Sulfatase DUF3687 PF12459.8 KFH41414.1 - 0.068 12.7 2.1 0.41 10.2 2.1 2.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein LysM PF01476.20 KFH41415.1 - 0.007 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Csm1 PF12539.8 KFH41416.1 - 1.2e-31 109.1 0.0 2.4e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TACC_C PF05010.14 KFH41416.1 - 2e-05 24.5 3.3 3.7e-05 23.6 3.3 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 KFH41416.1 - 0.0014 17.6 7.7 0.0026 16.7 7.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 KFH41416.1 - 0.0022 16.3 6.7 0.003 15.8 6.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PspA_IM30 PF04012.12 KFH41416.1 - 0.005 16.5 8.8 0.01 15.4 8.8 1.5 1 0 0 1 1 1 1 PspA/IM30 family YkyA PF10368.9 KFH41416.1 - 0.0056 16.4 5.7 0.0056 16.4 5.7 1.6 2 0 0 2 2 1 1 Putative cell-wall binding lipoprotein T3SSipB PF16535.5 KFH41416.1 - 0.012 16.1 7.3 0.012 16.1 7.3 1.9 2 0 0 2 2 1 0 Type III cell invasion protein SipB Exonuc_VII_L PF02601.15 KFH41416.1 - 0.013 15.1 2.8 0.019 14.6 2.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5094 PF17015.5 KFH41416.1 - 0.015 15.4 0.0 0.015 15.4 0.0 3.0 2 2 0 2 2 1 0 Domain of unknown function (DUF5094) SKA2 PF16740.5 KFH41416.1 - 0.035 13.9 6.7 0.76 9.6 2.4 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 KFH41416.1 - 0.045 13.9 4.1 0.093 12.9 4.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KFH41416.1 - 0.049 13.7 16.7 0.38 10.8 16.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KFH41416.1 - 0.055 13.9 1.5 1.3 9.5 0.1 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) MPS2 PF17060.5 KFH41416.1 - 0.057 12.7 1.0 0.093 12.0 1.0 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 THOC7 PF05615.13 KFH41416.1 - 0.1 12.8 12.2 2.7 8.3 12.1 2.6 1 1 0 1 1 1 0 Tho complex subunit 7 UPF0242 PF06785.11 KFH41416.1 - 0.12 12.4 9.6 0.22 11.6 9.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KFH41416.1 - 0.13 12.5 0.3 0.13 12.5 0.3 3.0 3 1 1 4 4 2 0 Haemolysin XhlA Atg14 PF10186.9 KFH41416.1 - 0.15 11.1 12.2 0.25 10.4 12.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KFH41416.1 - 0.23 12.1 6.1 4.6 7.9 0.2 3.7 1 1 1 3 3 3 0 SlyX DUF3138 PF11336.8 KFH41416.1 - 0.23 10.0 5.0 0.32 9.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Prefoldin_2 PF01920.20 KFH41416.1 - 0.25 11.3 9.6 2.3 8.2 0.6 3.4 1 1 2 3 3 3 0 Prefoldin subunit ATG16 PF08614.11 KFH41416.1 - 0.28 11.4 18.2 7.1 6.8 18.2 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4618 PF15397.6 KFH41416.1 - 0.32 10.4 7.7 0.79 9.1 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) ADIP PF11559.8 KFH41416.1 - 0.42 10.7 16.3 0.37 10.9 10.7 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 KFH41416.1 - 0.46 10.2 9.1 0.75 9.5 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.9 KFH41416.1 - 0.47 10.4 10.3 0.19 11.7 2.4 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 KFH41416.1 - 0.48 10.4 15.0 0.34 10.9 2.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AT_hook PF02178.19 KFH41416.1 - 0.49 10.4 21.8 0.22 11.5 0.4 3.8 3 0 0 3 3 3 0 AT hook motif TMPIT PF07851.13 KFH41416.1 - 0.55 9.4 2.9 0.86 8.8 2.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Fmp27_WPPW PF10359.9 KFH41416.1 - 0.7 8.7 5.1 1.1 8.1 5.1 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Syntaxin-6_N PF09177.11 KFH41416.1 - 0.78 10.3 9.6 9.9 6.8 4.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KFH41416.1 - 1.3 9.1 5.8 3 7.9 5.8 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFH41416.1 - 2.6 6.5 4.8 3.7 6.0 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 KFH41416.1 - 2.7 8.7 12.0 2.1 9.0 1.9 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 KFH41416.1 - 3.1 7.6 6.7 6 6.7 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KFH41416.1 - 3.7 7.9 9.3 3.1 8.1 0.7 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 KFH41416.1 - 3.8 7.4 10.9 16 5.5 0.6 3.4 1 1 2 3 3 3 0 Prefoldin subunit HAUS-augmin3 PF14932.6 KFH41416.1 - 4.8 6.7 13.8 13 5.3 13.9 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KFH41416.1 - 4.9 6.4 14.1 14 4.9 14.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFH41416.1 - 6.8 7.0 10.2 5.5 7.3 7.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 KFH41416.1 - 7 7.0 13.9 7.2 7.0 11.3 2.0 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 KFH41416.1 - 7.2 6.7 15.1 4.5 7.3 7.1 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KFH41416.1 - 7.5 6.8 13.6 1.9 8.7 4.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 KFH41416.1 - 8.9 4.1 9.9 0.57 8.0 4.6 1.7 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KFH41416.1 - 9.4 4.7 12.5 20 3.6 12.4 1.5 1 1 0 1 1 1 0 Macoilin family APG6_N PF17675.1 KFH41416.1 - 9.5 6.8 19.0 45 4.6 19.0 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 KFH41416.1 - 9.6 6.5 9.0 52 4.2 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper MCM PF00493.23 KFH41417.1 - 7.9e-98 326.0 0.2 1.2e-97 325.4 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFH41417.1 - 1.5e-31 108.9 0.1 2.8e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFH41417.1 - 2.4e-23 82.3 0.5 4.9e-23 81.3 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFH41417.1 - 1.5e-11 44.8 0.0 4.2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH41417.1 - 6.3e-07 29.0 0.0 7.2e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFH41417.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFH41417.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TFIIF_alpha PF05793.12 KFH41417.1 - 6.2 5.3 11.0 9.4 4.7 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Serinc PF03348.15 KFH41418.1 - 1.2e-161 538.4 11.2 1.4e-161 538.2 11.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) HC2 PF07382.11 KFH41419.1 - 0.17 11.9 17.9 0.3 11.1 17.9 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Adeno_E3_15_3 PF03307.14 KFH41419.1 - 5.1 7.1 9.5 1 9.4 0.7 3.2 1 1 2 3 3 3 0 Adenovirus 15.3kD protein in E3 region Sugar_tr PF00083.24 KFH41420.1 - 3.9e-74 250.1 18.6 4.4e-74 250.0 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41420.1 - 1.7e-21 76.5 50.3 2.3e-15 56.4 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KFH41420.1 - 0.015 13.6 1.9 0.022 13.1 1.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GET2 PF08690.10 KFH41420.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 ABC2_membrane_2 PF12679.7 KFH41420.1 - 0.2 10.9 4.8 0.35 10.1 4.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Cation_ATPase_C PF00689.21 KFH41420.1 - 7.7 6.2 10.5 22 4.7 10.5 1.8 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Pkinase PF00069.25 KFH41421.1 - 2.7e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41421.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PIG-L PF02585.17 KFH41422.1 - 8.8e-27 94.3 0.0 1.3e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_61 PF03443.14 KFH41426.1 - 2.1e-33 116.0 0.1 3.5e-32 112.0 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Luciferase_cat PF10285.9 KFH41426.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain PRANC PF09372.10 KFH41427.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Aldedh PF00171.22 KFH41429.1 - 8.7e-153 509.1 0.0 9.9e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bac_rhodopsin PF01036.18 KFH41430.1 - 1.3e-24 87.0 29.6 8.6e-17 61.5 21.3 2.0 2 0 0 2 2 2 2 Bacteriorhodopsin-like protein Iso_dh PF00180.20 KFH41431.1 - 2.2e-111 372.3 0.0 2.6e-111 372.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Radial_spoke PF04712.12 KFH41433.1 - 0.24 10.3 2.0 0.31 9.9 2.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein BNR_2 PF13088.6 KFH41434.1 - 3.6e-15 56.0 0.0 5.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 KFH41434.1 - 2.5e-10 40.2 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFH41434.1 - 0.75 10.0 8.8 0.77 10.0 1.0 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat adh_short_C2 PF13561.6 KFH41436.1 - 1.3e-62 211.5 0.1 1.5e-62 211.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH41436.1 - 2.9e-48 163.9 0.3 3.7e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH41436.1 - 9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH41436.1 - 0.00034 20.1 0.3 0.00086 18.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFH41436.1 - 0.0016 18.7 0.1 0.0024 18.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFH41436.1 - 0.047 13.6 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KFH41436.1 - 0.098 13.3 0.2 0.51 11.0 0.2 2.0 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain APH PF01636.23 KFH41437.1 - 2.8e-08 34.0 0.1 4.2e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH41437.1 - 2.2e-05 24.1 0.0 0.00011 21.9 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFH41437.1 - 0.18 11.4 0.0 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 RIO1 family Pkinase PF00069.25 KFH41437.1 - 0.24 10.7 0.0 2.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Fungal_trans PF04082.18 KFH41438.1 - 4.3e-22 78.4 0.9 6.6e-22 77.8 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KFH41438.1 - 2.3e-06 27.9 13.3 0.0064 17.2 3.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH41438.1 - 5.6e-06 26.5 15.4 0.0025 18.2 5.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFH41438.1 - 0.0018 18.5 0.0 0.026 14.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH41438.1 - 0.02 15.3 2.3 1.1 9.7 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFH41438.1 - 1.4 9.3 7.4 5.3 7.4 5.8 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFH41438.1 - 6.5 7.1 5.7 15 5.9 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon Med8 PF10232.9 KFH41439.1 - 0.0081 15.8 5.4 0.015 14.9 5.4 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CHB_HEX_C_1 PF13290.6 KFH41439.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain FAM199X PF15814.5 KFH41439.1 - 0.76 8.8 2.6 1.2 8.2 2.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 KFH41439.1 - 2.7 6.7 5.7 4.3 6.0 5.7 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KFH41439.1 - 4 7.2 10.1 7.8 6.2 10.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SARAF PF06682.12 KFH41439.1 - 7.1 6.2 11.2 0.17 11.5 3.3 2.0 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Nha1_C PF08619.10 KFH41440.1 - 1.3e-108 364.2 25.5 1.5e-108 364.0 25.5 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KFH41440.1 - 3.7e-74 249.8 23.6 4.4e-74 249.6 23.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 KFH41440.1 - 0.0057 16.9 2.2 0.046 14.0 0.2 2.9 3 0 0 3 3 3 1 Colicin E5 ribonuclease domain YrhC PF14143.6 KFH41440.1 - 0.92 9.6 8.2 0.13 12.4 0.6 3.0 3 0 0 3 3 3 0 YrhC-like protein Cyclase PF04199.13 KFH41441.1 - 8.1e-12 45.6 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 KFH41441.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SecY PF00344.20 KFH41442.1 - 3.4e-70 236.7 8.5 5e-70 236.2 8.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFH41442.1 - 3.4e-16 58.8 0.2 9.7e-16 57.3 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Fungal_trans PF04082.18 KFH41443.1 - 7.7e-17 61.2 0.4 5e-16 58.5 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41443.1 - 8.9e-09 35.3 9.1 1.5e-08 34.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sdh_cyt PF01127.22 KFH41444.1 - 9.3e-20 70.9 4.2 1.2e-19 70.5 4.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CorA PF01544.18 KFH41445.1 - 1.4e-11 44.3 3.5 7.6e-11 41.9 3.3 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KFH41445.1 - 6.6e-06 25.8 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.22 KFH41445.1 - 0.0074 16.3 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Ribosomal_L27 PF01016.19 KFH41446.1 - 1.1e-25 89.4 0.1 2.3e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein PhoLip_ATPase_C PF16212.5 KFH41447.1 - 1.2e-69 234.8 23.3 2.9e-69 233.6 23.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFH41447.1 - 1.4e-21 75.9 1.8 6.1e-21 73.9 0.3 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFH41447.1 - 1.4e-11 44.3 0.0 1.7e-10 40.8 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH41447.1 - 3.7e-11 43.7 0.1 3.7e-05 24.1 0.0 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFH41447.1 - 2.8e-09 36.7 0.1 8.7e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFH41447.1 - 0.0013 18.5 0.6 0.073 12.8 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Poxvirus_B22R PF04395.12 KFH41447.1 - 0.054 13.0 3.1 0.16 11.5 0.0 2.5 2 0 0 2 2 2 0 Poxvirus B22R protein Adaptin_binding PF10199.9 KFH41448.1 - 1.1e-08 35.7 5.9 3e-08 34.3 5.9 1.8 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 ABC_tran PF00005.27 KFH41449.1 - 1.1e-51 174.9 0.0 2.2e-31 109.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFH41449.1 - 7.4e-51 173.4 26.9 1.9e-32 113.0 7.4 3.8 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KFH41449.1 - 5.5e-08 32.5 0.1 0.041 13.3 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH41449.1 - 3.8e-06 27.6 0.1 0.014 15.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFH41449.1 - 0.0012 18.7 0.5 8.8 6.0 0.1 3.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KFH41449.1 - 0.0014 18.7 0.1 0.051 13.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFH41449.1 - 0.0017 18.0 0.8 2.3 8.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KFH41449.1 - 0.0021 17.2 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KFH41449.1 - 0.0024 17.8 0.1 3.6 7.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KFH41449.1 - 0.0032 17.1 0.1 0.26 10.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFH41449.1 - 0.0034 17.8 0.0 1 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KFH41449.1 - 0.0072 16.4 2.4 0.029 14.4 0.0 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain DUF2374 PF09574.10 KFH41449.1 - 0.011 15.5 1.1 0.057 13.2 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) AAA_30 PF13604.6 KFH41449.1 - 0.028 14.1 0.8 6.8 6.4 0.1 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KFH41449.1 - 0.034 13.4 0.2 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KFH41449.1 - 0.056 12.3 2.9 2 7.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KFH41449.1 - 0.071 12.9 0.2 19 4.9 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase Ubie_methyltran PF01209.18 KFH41449.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_7 PF12775.7 KFH41449.1 - 0.12 11.9 0.1 14 5.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KFH41449.1 - 0.12 12.3 0.0 15 5.5 0.1 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFH41449.1 - 0.16 12.2 1.5 20 5.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 KFH41449.1 - 0.2 11.7 0.3 3.8 7.6 0.0 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KFH41449.1 - 0.23 11.2 0.7 11 5.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 KFH41449.1 - 0.27 10.9 0.0 17 4.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain IPP-2 PF04979.14 KFH41451.1 - 2.6e-23 83.2 7.0 2.6e-23 83.2 7.0 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF4658 PF15555.6 KFH41451.1 - 0.37 10.9 5.7 0.7 10.0 4.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Homeodomain PF00046.29 KFH41452.1 - 2.7e-19 68.8 4.3 5.8e-19 67.7 4.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFH41452.1 - 0.0074 16.2 0.4 0.018 14.9 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain IPPT PF01715.17 KFH41453.1 - 8.5e-64 215.5 0.2 1.3e-63 214.8 0.2 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KFH41453.1 - 2.6e-06 27.0 0.0 5.4e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 KFH41453.1 - 0.00065 19.9 2.7 0.0072 16.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain zf-met PF12874.7 KFH41453.1 - 0.0058 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 KFH41453.1 - 0.0069 16.9 0.5 0.041 14.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFH41453.1 - 0.023 15.1 0.1 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Hpr_kinase_C PF07475.12 KFH41453.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 KFH41453.1 - 0.034 14.7 0.1 0.34 11.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 KFH41453.1 - 0.039 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SKI PF01202.22 KFH41453.1 - 0.043 13.9 0.1 11 6.2 0.0 3.4 3 1 0 3 3 3 0 Shikimate kinase AAA_28 PF13521.6 KFH41453.1 - 0.05 13.9 0.1 0.27 11.4 0.1 2.3 1 0 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.8 KFH41453.1 - 0.057 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Cytidylate_kin PF02224.18 KFH41453.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 KFH41453.1 - 0.093 13.1 0.6 0.26 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KFH41453.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 KFH41453.1 - 0.17 12.0 0.2 0.76 9.8 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Chon_Sulph_att PF06566.11 KFH41454.1 - 0.032 14.1 2.9 0.033 14.1 2.9 1.0 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain KAR9 PF08580.10 KFH41454.1 - 0.037 12.6 2.4 0.038 12.5 2.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TAF6_C PF07571.13 KFH41455.1 - 2e-25 88.9 0.1 4.4e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KFH41455.1 - 2.5e-22 78.8 0.2 4.1e-22 78.1 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KFH41455.1 - 0.0013 19.0 0.4 0.0023 18.3 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFH41455.1 - 0.09 12.9 0.2 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Cupin_3 PF05899.12 KFH41456.1 - 9.7e-07 28.4 0.5 3.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFH41456.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 KFH41456.1 - 0.0028 17.4 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Pirin_C_2 PF17954.1 KFH41456.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain CENP-C_C PF11699.8 KFH41456.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like SNF PF00209.18 KFH41458.1 - 1.1e-78 265.3 39.4 4.6e-54 184.0 15.4 2.5 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family adh_short PF00106.25 KFH41459.1 - 7.1e-22 77.8 0.1 1.1e-18 67.5 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41459.1 - 4.4e-09 36.2 0.2 1.5e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH41459.1 - 2.4e-08 34.1 0.1 3.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain IPU_b_solenoid PF18783.1 KFH41459.1 - 0.21 11.6 0.4 0.53 10.4 0.4 1.6 1 0 0 1 1 1 0 Isopullulanase beta-solenoid repeat Pkinase PF00069.25 KFH41460.1 - 1.2e-19 70.7 0.0 8.2e-11 41.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41460.1 - 1.3e-09 37.8 0.0 0.00046 19.6 0.0 3.0 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KFH41460.1 - 0.0031 17.5 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH41460.1 - 0.078 12.3 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KFH41460.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Iso_dh PF00180.20 KFH41461.1 - 3.6e-98 328.9 0.0 4.1e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KFH41461.1 - 0.025 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Clat_adaptor_s PF01217.20 KFH41462.1 - 1.4e-42 145.0 0.0 3.2e-42 143.8 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain TPT PF03151.16 KFH41463.1 - 2.6e-24 86.1 26.3 3.1e-24 85.8 26.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH41463.1 - 3.6e-05 23.9 37.1 0.0017 18.5 11.3 2.5 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KFH41463.1 - 0.0012 18.1 27.4 0.006 15.8 27.4 1.8 1 1 0 1 1 1 1 UAA transporter family SecE PF00584.20 KFH41463.1 - 0.042 13.8 4.4 2.9 7.9 0.2 3.5 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex HATPase_c PF02518.26 KFH41464.1 - 3.4e-31 108.1 0.0 9e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH41464.1 - 2.7e-20 72.6 0.1 6.7e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFH41464.1 - 3.8e-18 65.3 0.5 1.7e-17 63.2 0.5 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KFH41464.1 - 6.5e-13 49.2 0.0 3e-12 47.0 0.0 2.2 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 KFH41464.1 - 1.2e-12 48.6 2.2 3.8e-12 46.9 0.0 3.0 4 0 0 4 4 3 1 AAA ATPase domain GAF PF01590.26 KFH41464.1 - 1.6e-06 28.7 0.0 5.1e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KFH41464.1 - 4.8e-06 26.1 0.0 9.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.6 KFH41464.1 - 0.00014 22.0 1.9 0.17 12.2 0.5 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HATPase_c_3 PF13589.6 KFH41464.1 - 0.00049 19.9 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 KFH41464.1 - 0.00083 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.12 KFH41464.1 - 0.0058 16.6 0.2 0.82 9.6 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_35 PF14516.6 KFH41464.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 KFH41464.1 - 0.06 12.5 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 KFH41464.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_2 PF07719.17 KFH41464.1 - 0.068 13.3 1.3 2.7 8.3 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KFH41464.1 - 0.081 13.2 0.1 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.6 KFH41464.1 - 0.092 13.0 0.1 22 5.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFH41464.1 - 1 9.9 5.5 3.9 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CSL PF05207.13 KFH41465.1 - 5.4e-23 80.5 0.6 6.5e-23 80.2 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KFH41465.1 - 0.0013 18.8 0.4 0.002 18.2 0.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Toprim_C_rpt PF13368.6 KFH41465.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Prok-RING_1 PF14446.6 KFH41465.1 - 0.39 10.7 3.4 0.81 9.7 3.4 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2722 PF10846.8 KFH41466.1 - 1.5e-05 24.2 0.0 1.5e-05 24.2 0.0 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF2722) Frataxin_Cyay PF01491.16 KFH41467.1 - 2e-36 124.3 0.0 2.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Cytochrome_B PF00033.19 KFH41468.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b/b6/petB Complex1_LYR_2 PF13233.6 KFH41469.1 - 0.029 15.1 0.5 0.054 14.3 0.5 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.15 KFH41469.1 - 0.038 14.0 0.3 0.038 14.0 0.3 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) tRNA-synt_1 PF00133.22 KFH41470.1 - 2.9e-36 124.9 0.0 2.8e-28 98.6 0.0 3.2 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFH41470.1 - 1.1e-13 50.8 0.2 2.3e-09 36.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFH41470.1 - 3.1e-10 40.2 2.8 7.6e-10 38.9 2.8 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFH41470.1 - 6e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Sugar_tr PF00083.24 KFH41471.1 - 1.4e-101 340.6 17.7 1.7e-101 340.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41471.1 - 6.2e-25 87.9 34.5 1.5e-20 73.4 7.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH41471.1 - 1e-08 34.2 21.6 1.5e-06 27.1 5.3 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KFH41471.1 - 0.0016 17.5 2.5 0.0016 17.5 2.5 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 KFH41471.1 - 0.087 11.2 6.5 0.17 10.3 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector TB2_DP1_HVA22 PF03134.19 KFH41471.1 - 0.59 10.1 6.3 0.19 11.7 2.4 2.1 2 0 0 2 2 2 0 TB2/DP1, HVA22 family DEAD PF00270.29 KFH41472.1 - 1.5e-42 145.4 0.1 2.3e-42 144.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH41472.1 - 9.9e-31 106.4 0.0 1.9e-29 102.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41472.1 - 3.8e-08 33.5 0.0 6.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3734 PF12536.8 KFH41472.1 - 0.092 13.1 0.6 0.25 11.7 0.3 1.9 1 1 1 2 2 2 0 Patatin phospholipase TPR_17 PF13431.6 KFH41473.1 - 0.0049 17.2 0.0 0.053 13.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 KFH41474.1 - 1.2e-37 128.1 3.8 1.8e-37 127.6 3.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFH41474.1 - 0.001 19.0 1.1 0.0033 17.3 0.3 2.3 3 0 0 3 3 3 1 KOW motif Amino_oxidase PF01593.24 KFH41475.1 - 1.8e-06 27.6 0.0 3.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH41475.1 - 3.3e-05 24.0 0.1 7.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH41475.1 - 0.019 14.2 0.1 0.67 9.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.11 KFH41475.1 - 0.031 14.2 0.2 0.079 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) TrkA_N PF02254.18 KFH41475.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KFH41475.1 - 0.16 11.1 0.2 0.3 10.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Chs7 PF12271.8 KFH41476.1 - 1.5e-114 382.2 2.9 1.7e-114 382.0 2.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone UPF0220 PF05255.11 KFH41476.1 - 0.75 9.3 7.5 0.06 12.9 0.4 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) DUF2569 PF10754.9 KFH41476.1 - 1.4 9.4 15.1 5.5 7.4 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Ssl1 PF04056.14 KFH41479.1 - 4.2e-75 251.8 0.0 5.4e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFH41479.1 - 8.2e-17 61.8 0.0 1.8e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 KFH41479.1 - 3.6e-15 55.9 10.7 3.6e-15 55.9 10.7 2.6 2 1 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.28 KFH41479.1 - 4.9e-05 23.6 0.0 6.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Zn-ribbon_8 PF09723.10 KFH41479.1 - 0.46 10.7 16.3 0.65 10.2 4.8 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Glyoxalase PF00903.25 KFH41481.1 - 4.7e-24 85.0 0.2 4.4e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFH41481.1 - 4.1e-11 43.1 0.0 0.00011 22.5 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFH41481.1 - 2.5e-06 27.7 0.0 0.068 13.3 0.0 3.2 3 0 0 3 3 3 3 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KFH41481.1 - 0.00081 19.6 0.1 0.0083 16.3 0.0 2.3 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Cadherin_5 PF17892.1 KFH41481.1 - 0.039 13.9 1.1 0.068 13.1 0.3 1.8 2 0 0 2 2 2 0 Cadherin-like domain Big_9 PF17963.1 KFH41481.1 - 0.22 12.3 0.4 0.22 12.3 0.4 1.8 2 0 0 2 2 2 0 Bacterial Ig domain ABC_membrane_2 PF06472.15 KFH41482.1 - 5.1e-105 350.7 0.3 7.6e-105 350.2 0.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFH41482.1 - 2.4e-17 63.8 0.0 5.3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFH41482.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFH41482.1 - 0.0062 17.1 0.3 0.016 15.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFH41482.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KFH41482.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KFH41482.1 - 0.083 12.3 0.1 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KFH41482.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFH41482.1 - 0.11 12.8 1.1 0.76 10.1 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain Syntaxin PF00804.25 KFH41482.1 - 0.13 11.9 0.2 8.6 6.0 0.1 2.5 2 0 0 2 2 2 0 Syntaxin AAA_15 PF13175.6 KFH41482.1 - 0.23 11.1 0.1 0.39 10.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain NCE101 PF11654.8 KFH41483.1 - 1.5e-09 37.4 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 CTNNBL PF08216.11 KFH41484.1 - 7.1e-40 135.4 0.0 2.2e-39 133.8 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KFH41484.1 - 0.039 14.0 0.2 0.49 10.5 0.0 3.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFH41484.1 - 0.069 12.7 0.6 1.5 8.5 0.1 2.8 2 0 0 2 2 2 0 Atypical Arm repeat DUF5578 PF17741.1 KFH41484.1 - 0.31 10.4 3.2 4.9 6.5 0.0 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5578) ThiJ_like PF17124.5 KFH41485.1 - 5.4e-51 173.1 0.1 1.5e-50 171.6 0.1 1.6 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KFH41485.1 - 1.9e-10 40.8 0.0 1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 KFH41485.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family PET117 PF15786.5 KFH41486.1 - 4e-27 94.3 2.5 4.6e-27 94.1 2.5 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial IDO PF01231.18 KFH41487.1 - 1.3e-167 558.0 0.0 1.5e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase STE2 PF02116.15 KFH41488.1 - 2.5e-78 263.2 11.3 3.1e-78 262.9 11.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PalH PF08733.10 KFH41488.1 - 0.00028 20.0 8.3 0.00036 19.7 8.3 1.1 1 0 0 1 1 1 1 PalH/RIM21 MIT PF04212.18 KFH41489.1 - 7.9e-12 45.1 3.9 1.6e-11 44.1 3.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_hydro_16 PF00722.21 KFH41490.1 - 6.4e-15 55.1 1.2 1.2e-14 54.2 0.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KFH41490.1 - 7.9e-09 34.4 2.8 0.00013 20.5 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KFH41490.1 - 0.052 13.1 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) V-ATPase_G PF03179.15 KFH41491.1 - 2e-18 66.8 13.6 2.5e-18 66.6 13.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KFH41491.1 - 0.00055 20.3 8.7 0.00068 20.0 8.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF4775 PF16001.5 KFH41491.1 - 0.012 15.1 11.2 0.012 15.0 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) YusW PF14039.6 KFH41491.1 - 0.095 13.2 6.1 0.13 12.8 6.1 1.1 1 0 0 1 1 1 0 YusW-like protein Seryl_tRNA_N PF02403.22 KFH41491.1 - 0.4 10.9 12.2 0.4 10.9 11.3 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KFH41491.1 - 0.5 9.7 4.8 0.56 9.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 KFH41491.1 - 0.77 9.5 5.6 0.99 9.1 5.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CemA PF03040.14 KFH41491.1 - 2 8.3 3.8 2.5 8.0 3.8 1.0 1 0 0 1 1 1 0 CemA family TT_ORF1 PF02956.14 KFH41493.1 - 1.9 7.1 10.9 2.5 6.7 10.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 LMBR1 PF04791.16 KFH41493.1 - 4.2 6.2 5.1 0.27 10.1 0.2 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein zf-CCHC PF00098.23 KFH41494.1 - 1.2e-15 56.8 31.0 1.8e-05 24.6 2.3 4.8 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KFH41494.1 - 0.0074 16.0 21.9 0.096 12.4 1.1 4.1 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 KFH41494.1 - 0.39 10.7 0.3 0.39 10.7 0.3 4.0 2 2 1 3 3 3 0 Zinc knuckle DZR PF12773.7 KFH41494.1 - 1.2 9.2 19.0 0.78 9.8 4.2 2.8 2 1 1 3 3 3 0 Double zinc ribbon WD40 PF00400.32 KFH41495.1 - 1.7e-39 133.1 3.6 1.3e-05 25.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41495.1 - 1.3e-13 51.0 0.0 0.00024 21.3 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH41495.1 - 0.0077 15.2 0.0 0.72 8.7 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFH41495.1 - 0.041 12.6 1.0 11 4.7 0.1 3.0 1 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KFH41495.1 - 0.052 12.9 0.0 1.8 7.8 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KFH41495.1 - 0.14 10.7 0.9 27 3.2 0.2 3.2 1 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4763 PF15960.5 KFH41496.1 - 0.00024 20.5 1.2 0.00024 20.5 1.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4763) RRN3 PF05327.11 KFH41496.1 - 0.02 13.5 0.1 0.02 13.5 0.1 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CorA PF01544.18 KFH41496.1 - 0.68 9.2 10.7 1.3 8.2 0.6 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GrpE PF01025.19 KFH41496.1 - 1.8 8.2 6.0 6.9 6.3 0.8 2.4 2 0 0 2 2 2 0 GrpE Rootletin PF15035.6 KFH41496.1 - 2.1 8.3 24.0 25 4.8 18.9 3.0 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion LMBR1 PF04791.16 KFH41496.1 - 2.5 6.9 3.5 3.5 6.4 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-Q PF13094.6 KFH41496.1 - 7 6.8 17.9 3.4 7.8 9.6 3.0 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MCM PF00493.23 KFH41497.1 - 4.7e-100 333.3 0.8 6e-100 333.0 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFH41497.1 - 1.7e-38 131.3 0.2 3.2e-38 130.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KFH41497.1 - 1e-28 100.6 30.8 1e-28 100.6 30.8 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KFH41497.1 - 1e-25 90.0 0.6 2.5e-25 88.7 0.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFH41497.1 - 8e-14 52.1 0.1 1.9e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH41497.1 - 1.1e-07 31.4 0.0 5.3e-06 26.0 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFH41497.1 - 6.3e-06 26.2 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFH41497.1 - 0.0029 17.5 0.0 0.016 15.1 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFH41497.1 - 0.0044 16.7 0.2 0.031 14.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn-ribbon_8 PF09723.10 KFH41497.1 - 0.2 11.8 1.4 0.45 10.7 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_2 PF12674.7 KFH41497.1 - 0.24 12.1 0.5 0.74 10.5 0.5 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KFH41497.1 - 0.26 10.6 2.1 0.57 9.6 2.1 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Glyco_hydro_43 PF04616.14 KFH41499.1 - 3.6e-16 59.3 2.3 5.4e-16 58.7 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RNA_pol_Rpb2_6 PF00562.28 KFH41500.1 - 7.6e-127 423.6 0.1 1.5e-126 422.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFH41500.1 - 6e-52 176.1 0.0 4.4e-51 173.3 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFH41500.1 - 2.7e-46 157.6 0.0 5.8e-46 156.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KFH41500.1 - 2.7e-33 114.2 0.1 5.9e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KFH41500.1 - 2.8e-25 88.3 0.1 7e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFH41500.1 - 1.6e-23 83.0 1.1 4.4e-23 81.6 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KFH41500.1 - 3.5e-19 68.8 0.3 3.5e-19 68.8 0.3 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KFH41500.1 - 0.21 11.9 1.0 6.8 7.0 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain UEV PF05743.13 KFH41501.1 - 2.1e-39 134.1 0.1 4.4e-39 133.1 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KFH41501.1 - 2e-21 75.7 0.0 4.1e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain GTP_EFTU PF00009.27 KFH41502.1 - 4.6e-51 173.1 0.1 7.9e-51 172.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFH41502.1 - 3.4e-43 146.2 4.6 5.8e-43 145.4 4.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFH41502.1 - 1.4e-19 69.9 0.0 2.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFH41502.1 - 9.3e-06 25.9 0.2 1.9e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH41502.1 - 3.6e-05 23.8 0.0 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KFH41502.1 - 0.00031 20.8 0.1 0.0013 18.7 0.0 2.2 2 1 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 KFH41502.1 - 0.0038 17.1 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KFH41502.1 - 0.0047 16.5 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1_Xtn PF16897.5 KFH41502.1 - 0.04 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 KFH41502.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 KFH41502.1 - 0.34 11.1 2.7 0.76 10.0 2.7 1.5 1 0 0 1 1 1 0 Snurportin1 His_Phos_1 PF00300.22 KFH41503.1 - 2e-19 70.0 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KFH41503.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Protoglobin PF11563.8 KFH41504.1 - 1.9e-56 190.3 0.0 2.2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Protoglobin TRAPP PF04051.16 KFH41505.1 - 4.4e-35 120.5 0.0 5.2e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KFH41505.1 - 0.03 13.2 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KFH41505.1 - 0.055 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF1240 PF06836.12 KFH41506.1 - 0.12 13.0 0.1 0.36 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) zf-UBR PF02207.20 KFH41507.1 - 1.6e-13 50.6 4.2 1.6e-13 50.6 4.2 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.26 KFH41508.1 - 9.9e-157 522.6 1.0 1.3e-156 522.2 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFH41508.1 - 9.6e-40 135.4 0.1 1.6e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFH41508.1 - 8.2e-14 51.7 1.9 1.1e-13 51.3 0.3 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFH41508.1 - 0.1 12.9 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Toxin_20 PF08089.11 KFH41508.1 - 3.2 7.9 5.1 4.8 7.4 0.2 3.0 3 0 0 3 3 3 0 Huwentoxin-II family ParA PF10609.9 KFH41509.1 - 1e-90 303.5 0.1 1.3e-90 303.1 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFH41509.1 - 6.6e-11 42.4 0.0 4.7e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KFH41509.1 - 1.2e-05 24.7 0.1 8.3e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KFH41509.1 - 0.00012 22.1 0.3 0.0013 18.7 0.2 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KFH41509.1 - 0.00012 21.3 1.5 0.00014 21.2 0.6 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 KFH41509.1 - 0.0021 17.1 0.4 0.0035 16.4 0.4 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFH41509.1 - 0.0043 16.7 0.2 0.0076 15.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KFH41509.1 - 0.0047 16.4 0.1 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 KFH41509.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KFH41509.1 - 0.14 12.0 1.0 0.29 11.0 1.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KFH41509.1 - 0.26 11.6 0.7 0.65 10.4 0.7 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 KFH41509.1 - 0.42 10.4 2.1 32 4.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain p450 PF00067.22 KFH41510.1 - 3.4e-39 134.9 0.0 6.2e-38 130.7 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 APH PF01636.23 KFH41511.1 - 4.3e-09 36.7 0.1 5.8e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH41511.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YhhN PF07947.14 KFH41512.1 - 9.8e-35 119.8 13.1 1.2e-34 119.6 13.1 1.1 1 0 0 1 1 1 1 YhhN family adh_short PF00106.25 KFH41513.1 - 7.2e-07 28.9 0.0 1.1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41513.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KFH41513.1 - 0.029 14.1 0.8 0.057 13.2 0.8 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.16 KFH41513.1 - 0.077 12.6 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MIP PF00230.20 KFH41514.1 - 8.4e-11 42.0 0.9 9.1e-11 41.9 0.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein WW PF00397.26 KFH41515.1 - 1.4e-09 37.9 7.0 2.3e-09 37.2 7.0 1.4 1 0 0 1 1 1 1 WW domain GHMP_kinases_C PF08544.13 KFH41515.1 - 0.15 12.5 1.1 0.42 11.0 1.1 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal CCDC50_N PF15295.6 KFH41515.1 - 0.54 10.4 6.8 1.1 9.5 6.8 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus SAM_decarbox PF01536.16 KFH41516.1 - 1.5e-132 441.9 0.0 1.8e-132 441.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Lipase_GDSL_2 PF13472.6 KFH41517.1 - 6.1e-13 49.6 0.2 8.9e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH41517.1 - 0.00011 22.3 0.0 0.0022 18.0 0.0 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.19 KFH41518.1 - 6.7e-57 193.5 0.1 7.5e-57 193.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFH41518.1 - 8.4e-08 31.9 0.5 2.2e-06 27.3 0.5 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 KFH41518.1 - 0.028 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 KFH41519.1 - 1.3e-12 48.0 1.3 1.8e-12 47.5 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFH41519.1 - 1.8e-05 25.3 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain zf-Mss51 PF13824.6 KFH41520.1 - 0.1 12.7 0.0 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Virul_fac_BrkB PF03631.15 KFH41522.1 - 0.0047 16.6 5.9 0.0064 16.1 5.9 1.1 1 0 0 1 1 1 1 Virulence factor BrkB Cyt_bd_oxida_II PF02322.15 KFH41522.1 - 0.0053 16.2 5.6 0.0088 15.4 5.6 1.3 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF2434 PF10361.9 KFH41522.1 - 0.011 14.8 4.3 0.016 14.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) DUF4231 PF14015.6 KFH41522.1 - 0.055 14.0 1.1 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF805 PF05656.14 KFH41522.1 - 0.082 13.3 8.6 0.14 12.5 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF805) QueT PF06177.11 KFH41522.1 - 0.097 13.0 5.9 0.026 14.9 3.0 1.5 2 0 0 2 2 1 0 QueT transporter MIG-14_Wnt-bd PF06664.12 KFH41522.1 - 0.13 11.5 10.5 0.097 11.9 5.3 1.9 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion UPF0182 PF03699.13 KFH41522.1 - 0.46 8.5 5.0 0.61 8.1 5.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4064 PF13273.6 KFH41522.1 - 0.53 10.6 4.8 11 6.3 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 KFH41522.1 - 0.6 8.8 8.3 5 5.8 8.3 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) YfhO PF09586.10 KFH41522.1 - 1.1 7.4 7.6 0.7 8.0 2.5 2.0 1 1 1 2 2 2 0 Bacterial membrane protein YfhO DUF973 PF06157.11 KFH41522.1 - 1.1 8.2 3.7 2.6 7.0 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) MFS_1 PF07690.16 KFH41525.1 - 4.6e-37 127.8 29.4 1.2e-33 116.5 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41526.1 - 8.7e-74 249.0 21.3 1.1e-73 248.7 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41526.1 - 4.9e-22 78.3 27.5 5.8e-17 61.6 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.18 KFH41527.1 - 1.4e-58 198.5 34.0 1.6e-58 198.4 34.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TIP120 PF08623.10 KFH41528.1 - 4.9e-64 215.1 1.3 1.3e-62 210.5 0.0 3.9 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KFH41528.1 - 1.3e-14 54.3 21.7 0.011 16.1 0.1 9.7 6 4 2 8 8 7 5 HEAT repeats HEAT PF02985.22 KFH41528.1 - 5e-13 48.1 21.1 0.38 11.1 0.1 12.0 12 1 0 12 12 11 3 HEAT repeat RTP1_C1 PF10363.9 KFH41528.1 - 1.5e-10 41.3 4.7 0.016 15.4 0.0 6.7 6 2 2 8 8 8 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFH41528.1 - 2.4e-08 33.0 7.0 0.024 13.2 0.0 7.3 6 3 1 7 7 7 2 Adaptin N terminal region Cnd1 PF12717.7 KFH41528.1 - 5.2e-07 29.8 12.7 0.056 13.5 0.2 6.8 6 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KFH41528.1 - 0.00014 21.8 4.4 12 5.9 0.1 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 KFH41528.1 - 0.00015 22.3 0.2 6.8 7.4 0.0 6.4 8 0 0 8 8 7 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFH41528.1 - 0.00041 20.8 29.7 0.51 10.9 0.1 11.6 12 1 1 13 13 13 2 HEAT-like repeat RIX1 PF08167.12 KFH41528.1 - 0.0031 17.3 0.0 34 4.1 0.0 4.6 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Tti2 PF10521.9 KFH41528.1 - 0.0062 16.1 0.0 1.4 8.4 0.2 3.6 4 0 0 4 4 4 1 Tti2 family RICTOR_N PF14664.6 KFH41528.1 - 0.015 14.3 0.8 0.4 9.6 0.0 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Cnd3 PF12719.7 KFH41528.1 - 0.048 12.8 1.2 14 4.8 0.0 4.5 5 1 1 6 6 6 0 Nuclear condensing complex subunits, C-term domain Alkyl_sulf_dimr PF14863.6 KFH41528.1 - 0.062 13.8 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation VHS PF00790.19 KFH41528.1 - 0.073 12.9 0.2 2.8 7.8 0.0 3.1 2 0 0 2 2 2 0 VHS domain RasGEF_N_2 PF14663.6 KFH41528.1 - 0.074 13.5 0.2 2.7 8.4 0.0 3.8 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain T3SchapCesA PF11439.8 KFH41528.1 - 0.14 12.4 0.1 0.71 10.1 0.0 2.3 2 0 0 2 2 1 0 Type III secretion system filament chaperone CesA MMS19_C PF12460.8 KFH41528.1 - 3.9 6.5 9.9 1.4 7.9 0.2 4.5 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal NOB1_Zn_bind PF08772.11 KFH41529.1 - 4e-31 107.0 1.5 6.7e-31 106.3 1.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KFH41529.1 - 2.4e-29 101.7 0.0 4.8e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_5 PF08745.11 KFH41529.1 - 0.12 11.8 0.0 35 3.7 0.0 3.0 3 0 0 3 3 3 0 PINc domain ribonuclease zf-NADH-PPase PF09297.11 KFH41529.1 - 0.56 9.9 6.2 0.13 12.0 0.8 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.12 KFH41530.1 - 2.1e-20 72.5 0.1 3.3e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Glyco_hydro_61 PF03443.14 KFH41531.1 - 2.1e-67 227.1 0.1 2.4e-67 226.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KFH41531.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Ank_2 PF12796.7 KFH41532.1 - 4.2e-66 219.5 0.0 1.8e-08 34.8 0.0 16.2 7 5 7 16 16 16 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH41532.1 - 3e-65 215.8 11.6 3.1e-06 27.6 0.0 22.0 14 5 9 23 23 23 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH41532.1 - 2.1e-47 158.5 18.4 3.6e-06 27.1 0.1 18.8 16 3 2 18 18 18 12 Ankyrin repeats (many copies) Ank PF00023.30 KFH41532.1 - 7.8e-45 149.4 8.1 0.018 15.5 0.0 23.0 22 3 1 23 23 23 11 Ankyrin repeat Ank_3 PF13606.6 KFH41532.1 - 2e-41 135.2 1.9 0.025 15.1 0.0 22.7 25 0 0 25 25 25 8 Ankyrin repeat Melibiase_2 PF16499.5 KFH41533.1 - 2.7e-56 190.8 2.3 9.6e-56 189.0 2.3 1.8 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFH41533.1 - 3.5e-09 36.6 0.0 4.1e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFH41533.1 - 6.1e-07 28.7 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Melibiase GST_N_4 PF17172.4 KFH41534.1 - 1.7e-18 67.2 0.0 3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFH41534.1 - 3e-15 55.8 0.0 5.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFH41534.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KFH41534.1 - 0.069 13.4 0.2 0.16 12.3 0.1 1.7 1 1 1 2 2 2 0 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KFH41534.1 - 0.091 12.8 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hydrolase PF00702.26 KFH41535.1 - 5.8e-11 43.1 0.0 7.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFH41535.1 - 1.2e-10 41.7 0.0 2.9e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH41535.1 - 3.1e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TipAS PF07739.13 KFH41535.1 - 0.0021 18.6 0.6 0.1 13.2 0.1 2.4 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain SbcD_C PF12320.8 KFH41535.1 - 0.056 13.7 0.2 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Cons_hypoth95 PF03602.15 KFH41535.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HTH_28 PF13518.6 KFH41535.1 - 0.37 10.9 3.3 10 6.3 0.4 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Pkinase PF00069.25 KFH41536.1 - 9.3e-24 84.2 0.0 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41536.1 - 9.6e-12 44.7 0.0 4.4e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH41536.1 - 5.8e-07 28.6 0.0 9e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase IDO PF01231.18 KFH41537.1 - 6.8e-35 120.7 0.0 1e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CLTH PF10607.9 KFH41538.1 - 6.5e-28 97.5 0.4 1e-27 96.8 0.1 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFH41538.1 - 4.9e-25 88.0 0.1 8.4e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFH41538.1 - 5.6e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 LisH CDC14 PF08045.11 KFH41539.1 - 8.4e-131 435.2 0.0 9.5e-131 435.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component HAD_2 PF13419.6 KFH41540.1 - 2.4e-13 50.5 0.0 6.5e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH41540.1 - 9.5e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH41540.1 - 0.00025 21.0 0.1 0.00059 19.9 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFH41540.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TPMT PF05724.11 KFH41541.1 - 7.8e-26 91.1 0.0 8.1e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KFH41541.1 - 3.1e-07 30.4 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH41541.1 - 5.6e-05 23.7 0.0 0.00015 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41541.1 - 0.00013 22.6 0.0 0.00026 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH41541.1 - 0.00039 20.3 0.0 0.0037 17.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFH41541.1 - 0.0039 16.6 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KFH41541.1 - 0.0083 16.9 0.0 0.036 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain LETM1 PF07766.13 KFH41542.1 - 1.2e-11 44.5 0.6 7.6e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein NMO PF03060.15 KFH41544.1 - 3.3e-32 112.2 2.7 2.8e-27 96.0 0.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KFH41544.1 - 0.00044 19.4 4.8 0.00072 18.7 4.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFH41544.1 - 0.0024 16.9 5.3 0.071 12.1 5.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFH41544.1 - 0.024 13.8 0.3 0.037 13.2 0.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KFH41544.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase OTU PF02338.19 KFH41545.1 - 2.9e-19 69.8 1.2 1.4e-18 67.6 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFH41545.1 - 0.0047 16.4 0.0 0.41 10.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF4407 PF14362.6 KFH41545.1 - 5.4 6.3 14.6 9.1 5.5 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SANT_DAMP1_like PF16282.5 KFH41546.1 - 2.4e-30 104.5 0.1 4.7e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1_like PF17024.5 KFH41546.1 - 0.11 12.6 0.1 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative DMAP1-like YrhK PF14145.6 KFH41547.1 - 0.0018 18.1 16.4 0.38 10.6 2.4 5.2 4 1 1 5 5 5 3 YrhK-like protein EMP24_GP25L PF01105.24 KFH41548.1 - 1.2e-48 165.5 0.0 1.4e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.22 KFH41550.1 - 3.3e-51 173.1 0.0 7.2e-51 172.0 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFH41550.1 - 4e-17 62.5 0.0 5.9e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH41550.1 - 0.0014 18.1 0.0 0.0056 16.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFH41550.1 - 0.011 15.6 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KFH41550.1 - 0.015 14.8 0.1 0.16 11.5 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 KFH41550.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH41550.1 - 0.14 12.6 0.1 0.3 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain INO80_Ies4 PF08193.11 KFH41551.1 - 1.7e-79 267.3 25.5 2.1e-79 267.0 25.5 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 PDE8 PF08629.10 KFH41551.1 - 6.9 6.8 7.4 27 4.8 1.3 2.7 2 0 0 2 2 2 0 PDE8 phosphodiesterase Mcp5_PH PF12814.7 KFH41552.1 - 3.9e-46 156.1 0.0 7.6e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KFH41552.1 - 0.19 12.2 14.2 0.47 10.9 14.2 1.6 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 KFH41552.1 - 0.4 10.8 21.4 1.2 9.3 18.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFH41552.1 - 0.85 8.9 12.1 1.3 8.3 12.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KFH41552.1 - 6.3 6.6 9.4 14 5.4 9.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KFH41552.1 - 9 6.4 11.6 29 4.7 11.6 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding polyprenyl_synt PF00348.17 KFH41554.1 - 3.3e-64 216.4 0.0 4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short_C2 PF13561.6 KFH41555.1 - 4.4e-47 160.6 0.1 5.1e-47 160.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH41555.1 - 2.8e-41 141.1 0.0 3.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH41555.1 - 3.1e-09 37.0 0.0 4.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 KR domain GAF_2 PF13185.6 KFH41556.1 - 6.3e-09 36.2 0.0 8.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KFH41556.1 - 0.0014 19.2 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain SCP2 PF02036.17 KFH41557.1 - 3.7e-25 88.4 0.2 4.5e-25 88.1 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFH41557.1 - 3.4e-06 27.3 0.2 4.4e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFH41557.1 - 0.0031 17.9 0.0 0.0038 17.6 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain C2 PF00168.30 KFH41558.1 - 2.9e-15 56.4 0.0 4.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain Aldo_ket_red PF00248.21 KFH41559.1 - 3.1e-68 230.1 0.0 3.7e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 KFH41559.1 - 0.042 13.3 0.0 0.23 10.9 0.0 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PX PF00787.24 KFH41561.1 - 5.1e-21 74.8 0.5 1.3e-20 73.5 0.5 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFH41561.1 - 6.2e-09 35.8 7.0 0.00018 21.1 0.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KFH41561.1 - 0.0053 16.4 8.3 0.26 10.9 1.8 2.2 2 0 0 2 2 2 2 BAR domain BAR_3 PF16746.5 KFH41561.1 - 0.017 14.9 1.5 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 BAR domain of APPL family AlkA_N PF06029.11 KFH41561.1 - 0.024 14.9 0.0 0.072 13.4 0.0 1.9 1 0 0 1 1 1 0 AlkA N-terminal domain DUF3140 PF11338.8 KFH41561.1 - 0.031 14.7 1.3 0.072 13.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Sec34 PF04136.15 KFH41561.1 - 0.064 13.1 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KFH41561.1 - 0.8 9.7 2.9 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KFH41561.1 - 3.9 5.9 5.7 6.5 5.2 5.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KFH41562.1 - 3.2e-10 39.6 9.3 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFH41562.1 - 3.2e-07 29.6 0.0 0.0003 19.8 0.0 3.2 3 1 0 3 3 3 2 Vacuolar protein sorting 38 SPX PF03105.19 KFH41563.1 - 0.51 10.2 5.9 0.61 10.0 5.9 1.1 1 0 0 1 1 1 0 SPX domain NUDIX PF00293.28 KFH41565.1 - 1.6e-16 60.5 0.7 2e-16 60.2 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFH41565.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.6 1 1 0 1 1 1 0 NUDIX domain Isochorismatase PF00857.20 KFH41566.1 - 5e-18 65.9 0.1 2.7e-16 60.2 0.1 2.1 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_130 PF04041.13 KFH41567.1 - 1.4e-44 152.4 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KFH41567.1 - 4.1e-09 36.2 2.1 1.8e-06 27.5 0.0 3.8 3 1 0 4 4 4 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFH41567.1 - 1.3e-07 31.5 0.4 8.5e-07 28.8 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Dabb PF07876.12 KFH41568.1 - 1.6e-16 60.7 0.1 2e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.6 KFH41568.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) zf-SCNM1 PF15803.5 KFH41568.1 - 0.2 11.3 1.6 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Methyltransf_2 PF00891.18 KFH41570.1 - 8.6e-23 80.7 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KFH41570.1 - 0.0031 17.4 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 MarR family Dimerisation2 PF16864.5 KFH41570.1 - 0.007 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KFH41570.1 - 0.014 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.10 KFH41570.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Period_C PF12114.8 KFH41571.1 - 0.0019 17.8 3.2 0.003 17.2 3.2 1.2 1 0 0 1 1 1 1 Period protein 2/3C-terminal region RhlB PF12300.8 KFH41571.1 - 0.94 9.6 6.1 0.4 10.8 3.4 1.7 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB AF-4 PF05110.13 KFH41571.1 - 2.6 6.0 3.6 3.7 5.5 3.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S8 PF00082.22 KFH41572.1 - 1.3e-28 100.1 2.0 1.9e-28 99.6 2.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH41572.1 - 1.4e-15 57.7 0.0 2.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.32 KFH41574.1 - 7.7e-07 29.7 5.9 0.0007 20.4 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41574.1 - 0.0059 16.9 0.2 1.8 8.9 0.1 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Med3 PF11593.8 KFH41574.1 - 0.22 10.7 1.3 0.43 9.7 1.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PQQ_3 PF13570.6 KFH41574.1 - 1.1 9.9 4.4 22 5.7 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Ig_mannosidase PF17753.1 KFH41575.1 - 9e-15 54.2 0.0 1.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KFH41575.1 - 2.7e-10 40.7 0.0 1e-09 38.9 0.0 2.1 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFH41575.1 - 1.1e-06 29.3 0.0 2.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4299 PF14132.6 KFH41575.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) DUF4217 PF13959.6 KFH41575.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Glyco_hydro_20 PF00728.22 KFH41576.1 - 4.3e-89 299.4 0.0 5.6e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFH41576.1 - 1.3e-26 93.9 0.0 2.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFH41576.1 - 1.2e-07 32.6 0.3 3e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 P_proprotein PF01483.20 KFH41577.1 - 1.2e-27 95.8 1.4 2.7e-27 94.6 1.4 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 KFH41577.1 - 2.4e-25 89.4 1.0 5.1e-25 88.3 0.8 1.6 1 1 1 2 2 2 1 Subtilase family PepSY_TM PF03929.16 KFH41577.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region p450 PF00067.22 KFH41578.1 - 1.6e-26 93.1 0.0 1.7e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HMG-CoA_red PF00368.18 KFH41579.1 - 4.1e-141 470.2 6.9 5.7e-141 469.8 6.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KFH41579.1 - 3.8e-49 166.5 0.1 6.5e-49 165.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KFH41579.1 - 4.8e-14 52.5 8.0 7.2e-12 45.4 8.0 2.6 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFH41579.1 - 2e-09 36.1 3.0 3e-09 35.6 3.0 1.1 1 0 0 1 1 1 1 Patched family EVE PF01878.18 KFH41581.1 - 7.2e-45 152.6 0.0 1.3e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 EVE domain Utp14 PF04615.13 KFH41582.1 - 0.83 8.1 22.3 1 7.8 22.3 1.1 1 0 0 1 1 1 0 Utp14 protein WD40 PF00400.32 KFH41583.1 - 1e-23 83.1 7.1 4.9e-09 36.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41583.1 - 3.1e-06 27.4 0.1 0.046 14.0 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH41583.1 - 0.00011 21.3 0.0 0.056 12.4 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KFH41584.1 - 8.8e-23 80.7 8.5 0.081 13.5 0.0 12.2 10 4 2 13 13 13 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH41584.1 - 2.6e-13 50.2 12.2 0.0049 17.4 0.0 10.5 11 1 0 11 11 11 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH41584.1 - 8.2e-12 44.2 18.4 9.4 7.2 0.1 14.6 14 0 0 14 14 14 3 Ankyrin repeat Ank_5 PF13857.6 KFH41584.1 - 5.8e-09 36.0 16.4 1.5 9.2 0.0 9.4 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH41584.1 - 0.019 15.4 26.6 0.26 11.8 0.0 10.7 12 1 0 12 12 12 0 Ankyrin repeat SRR1 PF07985.12 KFH41585.1 - 5.6e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 SRR1 PUL PF08324.11 KFH41586.1 - 4.3e-68 229.5 0.1 6e-68 229.1 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFH41586.1 - 1.1e-45 154.5 0.5 1.8e-45 153.8 0.5 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFH41586.1 - 3.6e-30 103.6 11.8 9.4e-07 29.4 0.4 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFH41586.1 - 0.085 13.4 0.6 0.36 11.4 0.2 2.3 1 1 1 2 2 2 0 PQQ-like domain Glyco_hydro_17 PF00332.18 KFH41588.1 - 1.1e-08 35.0 2.4 3e-06 27.1 1.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ETRAMP PF09716.10 KFH41588.1 - 7.3 6.7 10.3 1.8 8.7 0.2 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.32 KFH41589.1 - 1.9e-13 50.6 1.7 0.67 10.9 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41589.1 - 0.0086 16.4 0.0 7.6 6.9 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VIT PF08487.10 KFH41591.1 - 8.9e-37 125.7 0.2 1.6e-36 124.9 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KFH41591.1 - 1.9e-27 96.1 0.0 3.7e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KFH41591.1 - 3e-15 55.8 0.1 6.2e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFH41591.1 - 1.7e-08 34.9 0.0 3.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFH41591.1 - 3.8e-07 30.7 0.0 1.3e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1655 PF07868.11 KFH41591.1 - 0.18 11.8 0.3 0.64 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) CAP_N PF01213.19 KFH41591.1 - 2.6 7.5 6.5 4.6 6.6 6.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.25 KFH41592.1 - 4.6e-36 124.1 0.0 5.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41592.1 - 6.7e-21 74.9 0.0 8.5e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH41592.1 - 4.4e-07 30.0 0.2 7.4e-07 29.2 0.2 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFH41592.1 - 9.1e-07 28.9 0.3 1.3e-06 28.4 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH41592.1 - 6e-05 22.6 0.2 0.0009 18.8 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFH41592.1 - 0.0047 17.2 0.2 0.012 15.9 0.2 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KFH41592.1 - 0.0071 16.9 0.1 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KFH41592.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFH41592.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase COPI_C PF06957.11 KFH41593.1 - 0.19 10.5 5.4 0.25 10.1 5.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Alpha_kinase PF02816.18 KFH41594.1 - 1.3e-51 175.3 0.1 2e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KFH41594.1 - 3.6e-11 43.6 0.0 8.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFH41594.1 - 7.6e-05 23.0 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFH41594.1 - 0.0035 17.3 0.1 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_12 PF13087.6 KFH41597.1 - 9.5e-33 113.5 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH41597.1 - 1.9e-22 80.3 2.0 1.6e-21 77.2 2.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH41597.1 - 2.4e-09 37.2 0.6 1.3e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH41597.1 - 1.9e-08 34.8 0.7 1.9e-07 31.5 0.7 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFH41597.1 - 0.0019 17.5 0.4 0.065 12.5 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFH41597.1 - 0.0041 16.6 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 KFH41597.1 - 0.0069 16.2 0.5 1.3 8.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFH41597.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFH41597.1 - 0.016 14.8 2.0 0.58 9.6 1.5 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KFH41597.1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 KFH41597.1 - 0.17 11.6 0.2 0.3 10.9 0.2 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Zn_clus PF00172.18 KFH41598.1 - 9.7e-07 28.8 2.9 1.8e-06 27.9 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH41598.1 - 1.2e-05 24.4 3.0 0.0022 16.8 1.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Acetyltransf_10 PF13673.7 KFH41599.1 - 7.1e-08 32.4 0.0 1.7e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH41599.1 - 1.1e-07 32.0 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH41599.1 - 2.2e-07 31.2 0.0 3.7e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KFH41599.1 - 0.0028 17.8 0.0 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH41599.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein GREB1 PF15782.5 KFH41600.1 - 4.2 4.4 14.7 4.9 4.1 14.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mlh1_C PF16413.5 KFH41600.1 - 8 5.7 6.9 2.7 7.3 1.0 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus HLH PF00010.26 KFH41601.1 - 3.2e-17 62.2 0.1 5.4e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KFH41601.1 - 0.036 14.2 0.2 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF2457 PF10446.9 KFH41601.1 - 0.073 12.2 3.7 0.083 12.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ZapB PF06005.12 KFH41601.1 - 0.11 12.9 0.0 2.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB E3_UbLigase_RBR PF18091.1 KFH41603.1 - 0.45 10.7 3.8 0.73 10.0 0.9 2.4 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain Hamartin PF04388.12 KFH41604.1 - 0.33 9.6 7.7 0.4 9.3 7.7 1.0 1 0 0 1 1 1 0 Hamartin protein ORC6 PF05460.13 KFH41604.1 - 1.9 7.7 9.8 2.4 7.3 9.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3464 PF11947.8 KFH41604.1 - 6.9 6.4 10.1 10 5.8 10.1 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 But2 PF09792.9 KFH41606.1 - 1.6e-10 41.5 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ACBP PF00887.19 KFH41607.1 - 1.9e-23 82.5 0.0 4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_S64 PF08192.11 KFH41607.1 - 0.015 13.8 2.6 0.017 13.6 2.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 MRP-S33 PF08293.11 KFH41608.1 - 4.7e-31 106.9 0.1 5.5e-31 106.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Molybdopterin PF00384.22 KFH41609.1 - 9.3e-74 248.9 0.0 7.1e-72 242.7 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFH41609.1 - 5e-21 74.5 0.3 1.5e-20 73.0 0.3 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KFH41609.1 - 4.1e-19 69.0 0.0 1.3e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KFH41609.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KFH41609.1 - 7.9e-09 35.4 0.6 7.9e-09 35.4 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFH41609.1 - 0.029 14.1 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 KFH41609.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 KFH41609.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF5572 PF17733.1 KFH41610.1 - 3.2e-18 65.3 0.9 6.8e-18 64.2 0.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF4880 PF16220.5 KFH41610.1 - 0.027 14.3 1.0 0.027 14.3 1.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) SLAC1 PF03595.17 KFH41611.1 - 2.2e-60 204.7 42.2 2.7e-60 204.3 42.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Nup_retrotrp_bd PF10599.9 KFH41611.1 - 0.17 12.5 0.2 0.48 11.1 0.2 1.7 1 0 0 1 1 1 0 Retro-transposon transporting motif Blt1 PF12754.7 KFH41612.1 - 1.7e-38 132.3 0.4 2.5e-38 131.7 0.4 1.3 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KFH41612.1 - 1.9e-18 65.7 0.7 3e-18 65.2 0.7 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KFH41612.1 - 0.0039 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Cpn60_TCP1 PF00118.24 KFH41613.1 - 1.2e-79 268.3 13.0 3.3e-79 266.8 13.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aldo_ket_red PF00248.21 KFH41614.1 - 2.1e-43 148.6 0.0 1.3e-41 142.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ACPS PF01648.20 KFH41614.1 - 0.1 12.8 0.4 0.29 11.3 0.3 1.8 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily DUF1751 PF08551.10 KFH41615.1 - 3.8e-05 24.2 0.1 6.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KFH41615.1 - 5e-05 23.3 1.2 0.00011 22.3 1.2 1.5 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KFH41615.1 - 0.072 13.0 2.7 0.11 12.4 2.7 1.2 1 0 0 1 1 1 0 Der1-like family LDB19 PF13002.7 KFH41617.1 - 0.23 11.1 0.9 0.43 10.3 0.9 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like baeRF_family3 PF18845.1 KFH41617.1 - 8.3 6.6 10.9 0.83 9.9 3.1 2.7 1 1 2 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 GHL6 PF14871.6 KFH41619.1 - 0.41 10.8 1.2 0.74 10.0 0.1 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 CHASE3 PF05227.13 KFH41619.1 - 0.55 10.1 4.7 0.45 10.4 0.2 2.6 3 0 0 3 3 3 0 CHASE3 domain DUF4366 PF14283.6 KFH41619.1 - 1.1 9.3 3.2 3.2 7.8 3.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) APH PF01636.23 KFH41620.1 - 5.2e-05 23.3 0.0 6.9e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFH41620.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PAN_4 PF14295.6 KFH41621.1 - 0.0099 15.8 4.1 0.011 15.7 2.8 1.8 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 KFH41621.1 - 0.046 13.7 0.1 0.046 13.7 0.1 1.8 2 0 0 2 2 2 0 PAN domain Ribonuclease_3 PF00636.26 KFH41623.1 - 5.5e-18 65.5 0.0 1.5e-17 64.1 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFH41623.1 - 2.9e-09 37.2 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KFH41623.1 - 0.011 16.4 0.0 0.011 16.4 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif Staufen_C PF16482.5 KFH41623.1 - 0.093 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Staufen C-terminal domain DUF2802 PF10975.8 KFH41623.1 - 6 7.1 6.2 28 4.9 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) PUF PF00806.19 KFH41624.1 - 3.3e-40 133.5 0.1 3e-06 26.6 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 KFH41624.1 - 0.17 12.0 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 RasGEF domain Phage_lambda_P PF06992.11 KFH41624.1 - 0.18 11.6 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Replication protein P UPF0061 PF02696.14 KFH41625.1 - 6.1e-121 404.4 0.0 3.8e-120 401.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1127 PF06568.11 KFH41625.1 - 0.1 12.3 2.2 0.17 11.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) PP2C PF00481.21 KFH41626.1 - 5.1e-43 147.6 0.0 7.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFH41626.1 - 0.001 18.8 0.5 0.0019 17.9 0.1 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KFH41626.1 - 0.0031 17.4 0.1 0.083 12.8 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cofilin_ADF PF00241.20 KFH41627.1 - 1.1e-10 41.3 0.9 1.5e-10 41.0 0.9 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XRCC4 PF06632.12 KFH41629.1 - 3e-08 32.9 11.5 1.5e-07 30.6 11.6 1.7 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 LptF_LptG PF03739.14 KFH41629.1 - 0.079 11.8 0.4 0.13 11.1 0.4 1.3 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Spc24 PF08286.11 KFH41629.1 - 2.4 8.4 5.9 0.45 10.8 0.7 2.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Methyltr_RsmB-F PF01189.17 KFH41630.1 - 1e-74 250.6 0.0 1.6e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFH41630.1 - 4.8e-08 33.4 0.0 1.4e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KFH41630.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KFH41630.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2431 PF10354.9 KFH41630.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.6 KFH41630.1 - 0.014 16.1 0.0 0.035 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFH41630.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KFH41630.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) EF-hand_4 PF12763.7 KFH41631.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFH41631.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KFH41631.1 - 0.18 12.3 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KFH41631.1 - 0.24 11.3 0.0 0.44 10.4 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair MFS_1 PF07690.16 KFH41632.1 - 3.7e-20 72.1 74.7 1.6e-12 47.0 37.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 KFH41632.1 - 0.51 10.0 3.3 3.1 7.5 0.3 3.2 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Myb_DNA-bind_6 PF13921.6 KFH41633.1 - 2.4e-12 46.9 0.3 2.8e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFH41633.1 - 1.7e-09 37.7 0.4 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SNF2_N PF00176.23 KFH41634.1 - 2.4e-67 227.1 0.0 5e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41634.1 - 2.5e-16 60.0 0.0 8.2e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41634.1 - 7e-07 29.4 0.0 2.4e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFH41634.1 - 0.0005 19.3 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ABC_tran_CTD PF16326.5 KFH41634.1 - 0.19 12.0 3.0 0.33 11.2 0.6 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain FliJ PF02050.16 KFH41634.1 - 0.43 10.8 11.0 0.23 11.7 7.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 KFH41635.1 - 3.9e-32 111.6 36.0 3.9e-32 111.6 36.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily S1 PF00575.23 KFH41636.1 - 3.4e-80 264.4 29.6 1e-14 54.6 0.7 13.9 13 1 0 13 13 13 11 S1 RNA binding domain TPR_19 PF14559.6 KFH41636.1 - 0.00015 22.2 0.0 2 9.0 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH41636.1 - 0.00029 21.4 6.4 3.3 8.8 0.0 6.3 4 2 4 8 8 8 1 Tetratricopeptide repeat S1_2 PF13509.6 KFH41636.1 - 0.00063 19.8 0.0 19 5.4 0.0 6.1 6 0 0 6 6 6 0 S1 domain RNase_II_C_S1 PF18614.1 KFH41636.1 - 0.0048 16.8 12.5 9.3 6.3 0.1 7.7 9 0 0 9 9 9 1 RNase II-type exonuclease C-terminal S1 domain NRDE-2 PF08424.10 KFH41636.1 - 0.0052 16.0 0.3 0.032 13.4 0.1 2.3 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference Suf PF05843.14 KFH41636.1 - 0.0074 16.3 8.7 0.064 13.2 0.3 3.6 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KFH41636.1 - 0.036 14.3 0.0 0.44 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AEP1 PF17049.5 KFH41636.1 - 0.047 12.8 0.1 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 ATPase expression protein 1 RPN7 PF10602.9 KFH41636.1 - 0.071 12.8 0.7 0.24 11.1 0.7 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Hemerythrin PF01814.23 KFH41637.1 - 1.6e-13 51.4 1.1 2.5e-13 50.8 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Aldo_ket_red PF00248.21 KFH41639.1 - 5.2e-69 232.7 0.0 6.3e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-S_biosyn PF01521.20 KFH41640.1 - 2.2e-11 43.9 0.0 1.2e-09 38.3 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_M16_C PF05193.21 KFH41641.1 - 6.7e-51 172.9 0.0 1.2e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFH41641.1 - 1.3e-41 142.0 0.0 4.3e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Ribosomal_S11 PF00411.19 KFH41642.1 - 2.6e-39 134.0 1.8 3.6e-39 133.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 MAP65_ASE1 PF03999.12 KFH41643.1 - 1.9e-78 264.7 2.6 4.8e-78 263.4 2.6 1.6 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.6 KFH41643.1 - 0.22 10.9 10.2 0.096 12.0 2.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 KFH41643.1 - 1.4 7.7 15.6 0.53 9.1 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Sipho_Gp157 PF05565.11 KFH41643.1 - 1.7 8.6 8.8 1.4 8.9 1.7 2.7 2 0 0 2 2 2 0 Siphovirus Gp157 BLOC1_2 PF10046.9 KFH41643.1 - 2.8 8.3 6.2 5.8 7.3 0.0 3.7 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 KFH41643.1 - 4.9 7.3 6.7 0.94 9.7 0.4 2.9 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Prominin PF05478.11 KFH41643.1 - 6.8 4.5 4.7 18 3.1 0.8 2.5 2 1 0 2 2 2 0 Prominin SKA2 PF16740.5 KFH41643.1 - 6.9 6.5 8.1 2.1 8.2 0.4 3.8 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 Spectrin PF00435.21 KFH41643.1 - 9.9 6.7 18.9 0.099 13.1 0.6 4.3 4 1 1 5 5 5 0 Spectrin repeat Arylsulfotran_2 PF14269.6 KFH41644.1 - 1.2e-52 179.2 2.0 1.7e-52 178.7 2.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFH41644.1 - 8e-19 67.8 0.3 2.2e-18 66.3 0.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ribosomal_L24e PF01246.20 KFH41645.1 - 7e-27 93.5 4.1 1.3e-26 92.6 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5078 PF16877.5 KFH41645.1 - 0.012 16.0 0.3 0.021 15.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Zn_clus PF00172.18 KFH41646.1 - 1.9e-15 56.7 25.1 2.2e-08 34.1 8.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41646.1 - 3.8e-15 55.6 0.0 6.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_32 PF13565.6 KFH41646.1 - 0.13 12.9 0.2 49 4.6 0.0 3.5 4 0 0 4 4 4 0 Homeodomain-like domain FHA PF00498.26 KFH41647.1 - 1e-14 54.6 0.1 2.6e-14 53.3 0.0 1.8 2 0 0 2 2 1 1 FHA domain zf-RING_11 PF17123.5 KFH41647.1 - 6.6e-13 48.1 6.5 1.2e-12 47.3 6.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFH41647.1 - 1.4e-07 31.7 9.7 2.4e-07 31.0 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KFH41647.1 - 0.0039 17.5 0.0 0.0078 16.5 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 KFH41647.1 - 0.014 15.2 4.1 0.026 14.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KFH41647.1 - 0.017 15.1 6.7 0.028 14.4 6.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KFH41647.1 - 0.02 14.8 9.3 0.033 14.1 9.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH41647.1 - 0.031 14.1 9.0 0.055 13.3 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH41647.1 - 0.059 13.7 6.2 0.15 12.4 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFH41647.1 - 0.13 12.3 9.0 0.31 11.1 9.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TFIIA PF03153.13 KFH41647.1 - 2.3 8.1 7.4 20 5.0 7.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 KFH41647.1 - 7.1 6.9 7.3 16 5.7 7.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.11 KFH41647.1 - 7.3 6.6 5.9 1e+02 2.9 5.9 2.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ApbA_C PF08546.11 KFH41648.1 - 3.6e-25 88.6 0.0 7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFH41648.1 - 2.8e-18 66.0 0.0 8.5e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA XylR_N PF06505.11 KFH41648.1 - 0.054 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism GMC_oxred_C PF05199.13 KFH41649.1 - 1.7e-08 35.1 0.1 3.5e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFH41649.1 - 1.6e-06 27.7 0.0 6.2e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 GMC oxidoreductase Abhydrolase_6 PF12697.7 KFH41649.1 - 1.4e-05 25.8 2.7 0.00043 21.0 0.8 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_2 PF00890.24 KFH41649.1 - 0.003 16.7 0.3 0.0055 15.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH41649.1 - 0.061 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF935 PF06074.12 KFH41650.1 - 2.2 6.9 7.4 4.7 5.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF935) PEX11 PF05648.14 KFH41651.1 - 0.013 15.0 2.4 1.9 7.9 0.4 2.7 2 1 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MBOAT_2 PF13813.6 KFH41652.1 - 6.6e-22 77.6 1.7 1.4e-21 76.6 1.7 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SUIM_assoc PF16619.5 KFH41653.1 - 2.1 8.5 12.1 0.2 11.7 1.0 4.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 eIF-3c_N PF05470.12 KFH41654.1 - 3.7e-170 567.2 22.3 1.2e-137 459.8 1.2 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KFH41654.1 - 1.9e-10 41.2 0.0 5.6e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain PDE4_UCR PF18100.1 KFH41654.1 - 0.032 14.9 2.6 0.035 14.8 0.1 2.4 2 1 1 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF4337 PF14235.6 KFH41654.1 - 0.075 13.2 2.1 0.23 11.6 2.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Streptin-Immun PF11083.8 KFH41654.1 - 0.19 12.1 3.1 0.38 11.2 1.0 2.7 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Ribosomal_L30_N PF08079.12 KFH41655.1 - 4.3e-26 91.0 18.8 7.2e-26 90.2 18.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFH41655.1 - 1.4e-17 63.3 2.8 1.4e-17 63.3 2.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Aldose_epim PF01263.20 KFH41656.1 - 2.9e-40 138.4 0.0 3.7e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase NMO PF03060.15 KFH41658.1 - 1.1e-51 176.2 2.5 1.4e-51 175.8 2.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFH41658.1 - 4.3e-08 32.5 5.6 3.5e-07 29.6 5.6 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFH41658.1 - 2e-05 23.8 4.3 2e-05 23.8 4.3 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase F-box-like PF12937.7 KFH41659.1 - 2.6e-06 27.2 0.1 6.5e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH41659.1 - 8.6e-05 22.3 0.4 0.00027 20.7 0.4 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KFH41659.1 - 0.096 13.2 0.1 29 5.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) AP1AR PF15745.5 KFH41660.1 - 0.037 13.7 0.3 0.07 12.7 0.3 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SNF2_N PF00176.23 KFH41661.1 - 5.4e-47 160.2 0.3 1.5e-45 155.5 0.1 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41661.1 - 2.6e-14 53.5 0.0 7.8e-14 52.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41661.1 - 9.5e-08 32.2 0.1 9.5e-08 32.2 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KFH41661.1 - 4.5e-06 26.4 10.3 4.5e-06 26.4 10.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH41661.1 - 0.00095 19.4 12.1 0.00095 19.4 12.1 2.6 2 0 0 2 2 2 1 Ring finger domain AAA_34 PF13872.6 KFH41661.1 - 0.0021 17.0 0.0 0.006 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.6 KFH41661.1 - 0.0046 16.8 10.4 0.0046 16.8 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH41661.1 - 0.011 15.5 10.6 0.011 15.5 10.6 2.1 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KFH41661.1 - 0.078 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-Nse PF11789.8 KFH41661.1 - 0.62 9.9 4.8 2 8.3 4.8 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFH41661.1 - 1.1 9.2 10.8 3.2 7.7 10.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFH41661.1 - 1.3 9.1 10.8 3.5 7.7 10.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 KFH41661.1 - 3.9 7.6 10.5 3 8.0 2.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Zn_clus PF00172.18 KFH41662.1 - 1.9e-17 63.1 24.8 1.5e-09 37.8 6.4 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41662.1 - 9e-14 51.1 0.1 1.6e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 KFH41663.1 - 4e-34 118.0 2.5 4.7e-34 117.8 2.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH41663.1 - 3.3e-16 59.2 29.9 1.5e-15 57.0 28.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41663.1 - 3.6e-07 29.4 8.9 3.6e-07 29.4 8.9 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter DUF1475 PF07343.11 KFH41663.1 - 0.0047 16.8 0.4 0.011 15.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) MFS_3 PF05977.13 KFH41663.1 - 0.013 13.9 1.1 0.02 13.3 0.5 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector ABM PF03992.16 KFH41664.1 - 0.031 14.4 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase NUDE_C PF04880.13 KFH41664.1 - 0.17 12.4 0.3 0.26 11.7 0.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ral PF11058.8 KFH41665.1 - 0.013 15.1 0.1 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 Antirestriction protein Ral bZIP_1 PF00170.21 KFH41665.1 - 0.3 11.2 5.3 0.59 10.3 5.3 1.6 1 1 0 1 1 1 0 bZIP transcription factor Glyco_hydro_3 PF00933.21 KFH41666.1 - 5.6e-44 150.8 0.0 8.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KFH41666.1 - 4.3e-43 147.7 0.1 1.3e-42 146.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFH41666.1 - 4.8e-22 77.9 0.2 8.9e-22 77.0 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SurE PF01975.17 KFH41667.1 - 1.8e-29 102.9 0.0 2.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE COG2 PF06148.11 KFH41668.1 - 2.8e-25 88.9 0.1 4e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KFH41668.1 - 0.0005 20.1 0.1 0.0089 16.1 0.0 2.5 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 KFH41668.1 - 0.0023 18.1 0.1 0.005 17.0 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.11 KFH41668.1 - 0.024 13.5 0.2 0.045 12.6 0.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Pil1 PF13805.6 KFH41668.1 - 0.032 13.7 0.2 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Eisosome component PIL1 Vps54_N PF10475.9 KFH41668.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DLP_helical PF18709.1 KFH41668.1 - 0.16 11.1 0.3 0.57 9.3 0.1 1.8 2 0 0 2 2 2 0 Dynamin-like helical domain HrpB7 PF09486.10 KFH41668.1 - 0.29 11.5 4.6 1 9.8 0.2 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) DEAD PF00270.29 KFH41670.1 - 2.4e-48 164.2 0.0 4.5e-48 163.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH41670.1 - 6.3e-26 90.9 0.0 2.9e-24 85.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFH41670.1 - 7.2e-19 67.8 0.3 1.7e-18 66.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KFH41670.1 - 5.7e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFH41670.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PARP PF00644.20 KFH41671.1 - 7e-60 202.0 0.3 4.5e-59 199.3 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFH41671.1 - 2.1e-45 154.2 0.1 3.2e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KFH41671.1 - 2.8e-24 85.0 0.1 7.9e-24 83.5 0.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KFH41671.1 - 1.3e-12 47.9 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFH41671.1 - 2.8e-07 30.9 0.0 6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KFH41671.1 - 8.5e-06 25.6 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LEA_4 PF02987.16 KFH41672.1 - 0.0042 17.1 3.9 0.0071 16.4 3.9 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.7 KFH41672.1 - 0.014 15.9 0.6 0.022 15.3 0.6 1.3 1 0 0 1 1 1 0 YtxH-like protein Ribosomal_L38e PF01781.18 KFH41673.1 - 3.2e-33 113.6 4.3 3.6e-33 113.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family NTF2 PF02136.20 KFH41674.1 - 0.0097 16.5 0.8 0.16 12.5 0.8 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NmrA PF05368.13 KFH41675.1 - 3.1e-14 53.1 0.0 4.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH41675.1 - 9.9e-09 35.3 0.0 1.7e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH41675.1 - 0.00038 20.0 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFH41675.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GHMP_kinases_N PF00288.26 KFH41676.1 - 2.6e-16 59.6 0.0 6.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFH41676.1 - 8.2e-09 35.7 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal SBF PF01758.16 KFH41677.1 - 2.4e-50 170.9 7.9 2.4e-50 170.9 7.9 1.9 2 1 0 2 2 2 1 Sodium Bile acid symporter family LRR_6 PF13516.6 KFH41678.1 - 3e-05 23.7 2.2 2.1 8.6 0.1 5.9 7 0 0 7 7 7 2 Leucine Rich repeat AMP_N PF05195.16 KFH41678.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Ribosomal_L1 PF00687.21 KFH41679.1 - 2.5e-28 99.2 0.0 3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Salt_tol_Pase PF09506.10 KFH41679.1 - 0.071 11.9 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Ribosomal_L34 PF00468.17 KFH41680.1 - 1.7e-08 34.3 12.4 2.8e-08 33.6 12.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Treslin_N PF15292.6 KFH41680.1 - 0.025 12.9 0.2 0.03 12.7 0.2 1.1 1 0 0 1 1 1 0 Treslin N-terminus Hap4_Hap_bind PF10297.9 KFH41681.1 - 1.1e-08 34.9 6.9 1.1e-08 34.9 6.9 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KFH41681.1 - 2.4e-05 24.3 8.8 5e-05 23.3 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor dsrm PF00035.26 KFH41681.1 - 0.089 13.5 0.0 0.33 11.7 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Atg14 PF10186.9 KFH41681.1 - 1.8 7.6 7.0 2.8 7.0 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 KFH41681.1 - 5 7.3 17.2 6.6 6.9 13.5 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Fmp27_WPPW PF10359.9 KFH41681.1 - 9.8 4.9 9.0 14 4.4 9.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PPTA PF01239.22 KFH41682.1 - 1.9e-37 125.9 25.9 2e-07 30.5 0.2 6.4 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 KFH41682.1 - 0.009 16.0 1.9 0.99 9.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH41682.1 - 0.1 13.1 0.2 8.4 7.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFH41682.1 - 0.28 11.9 2.1 0.5 11.2 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH41682.1 - 1.3 9.8 4.5 2.1 9.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.11 KFH41683.1 - 7.1e-96 321.3 2.1 1.4e-95 320.3 2.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFH41683.1 - 6.5e-23 80.8 5.1 2.1e-10 39.5 0.0 3.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.7 KFH41683.1 - 1e-19 71.6 0.2 4.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.19 KFH41683.1 - 4.8e-08 32.7 0.1 0.0023 17.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KFH41683.1 - 0.0039 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FR47 PF08445.10 KFH41683.1 - 0.061 13.3 0.1 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein FAD_binding_4 PF01565.23 KFH41684.1 - 9.6e-20 70.7 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Sedlin_N PF04628.13 KFH41685.1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BA14K PF07886.11 KFH41685.1 - 0.16 11.9 0.5 0.38 10.7 0.3 1.7 2 0 0 2 2 2 0 BA14K-like protein Nucleoporin_C PF03177.14 KFH41686.1 - 1e-170 569.4 1.4 1.2e-170 569.1 1.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KFH41686.1 - 5.6e-84 282.4 0.0 6.9e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pribosyl_synth PF14572.6 KFH41688.1 - 0.17 11.9 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain PNGaseA PF12222.8 KFH41689.1 - 1.8e-94 317.0 1.3 1.3e-52 179.1 0.0 3.1 2 1 1 3 3 3 3 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 KFH41690.1 - 5.6e-23 81.3 0.1 1e-22 80.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3169 PF11368.8 KFH41690.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Glyco_tran_28_C PF04101.16 KFH41691.1 - 2.2e-18 66.8 0.0 9.3e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KFH41691.1 - 0.067 12.4 0.0 0.087 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Alba PF01918.21 KFH41692.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Alba Aldedh PF00171.22 KFH41693.1 - 8.2e-73 245.5 0.0 9.8e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tctex-1 PF03645.13 KFH41694.1 - 2.9e-39 133.4 0.0 3.4e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family HTH_47 PF16221.5 KFH41694.1 - 0.18 11.4 0.0 0.52 9.9 0.0 1.7 2 0 0 2 2 2 0 winged helix-turn-helix DUF4536 PF15055.6 KFH41695.1 - 0.0015 18.7 4.7 0.0026 18.0 4.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Fringe PF02434.16 KFH41696.1 - 0.00022 20.8 0.3 0.0027 17.2 0.3 2.1 1 1 0 1 1 1 1 Fringe-like Acyl_transf_1 PF00698.21 KFH41697.1 - 6e-19 68.7 0.0 3.1e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain SPX PF03105.19 KFH41698.1 - 4.8e-07 30.0 1.5 0.00019 21.5 0.0 3.3 2 1 1 3 3 3 2 SPX domain DUF2721 PF11026.8 KFH41698.1 - 1.5 8.7 4.1 0.49 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CFEM PF05730.11 KFH41700.1 - 0.0055 16.8 11.2 0.0098 16.0 11.2 1.4 1 0 0 1 1 1 1 CFEM domain Pex19 PF04614.12 KFH41700.1 - 0.0069 16.2 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Pex19 protein family Furin-like_2 PF15913.5 KFH41700.1 - 0.19 11.9 5.7 0.28 11.4 5.7 1.2 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich AFG1_ATPase PF03969.16 KFH41701.1 - 4e-54 183.9 0.0 7.9e-26 90.8 0.0 5.0 5 0 0 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.6 KFH41701.1 - 7.5e-05 23.2 0.3 0.02 15.3 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFH41701.1 - 0.00096 19.4 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KFH41701.1 - 0.015 15.2 0.1 0.73 9.6 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_29 PF13555.6 KFH41701.1 - 0.033 13.9 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KFH41701.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KFH41701.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.14 KFH41701.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase eIF-5_eIF-2B PF01873.17 KFH41702.1 - 2.1e-41 140.4 0.5 3.3e-41 139.8 0.5 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Med19 PF10278.9 KFH41702.1 - 0.046 13.7 6.4 0.17 11.8 6.7 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TF_Zn_Ribbon PF08271.12 KFH41702.1 - 0.13 11.8 0.7 0.27 10.8 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1214 PF06742.11 KFH41702.1 - 0.17 12.3 0.1 2.8 8.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1214) zf-HYPF PF07503.12 KFH41702.1 - 0.86 9.4 3.9 5.5 6.9 4.2 2.2 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KFH41702.1 - 1.5 9.2 8.1 1.4 9.3 0.4 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.23 KFH41703.1 - 1.9e-19 70.2 13.9 2.1e-19 70.0 13.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF4698 PF15769.5 KFH41704.1 - 0.026 13.6 1.1 0.031 13.3 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) KAR9 PF08580.10 KFH41704.1 - 0.036 12.6 2.7 0.038 12.5 2.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SR-25 PF10500.9 KFH41704.1 - 0.9 9.1 6.9 1.3 8.5 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HMG14_17 PF01101.18 KFH41705.1 - 0.041 14.8 3.1 0.093 13.7 0.4 2.5 2 0 0 2 2 2 0 HMG14 and HMG17 DUF202 PF02656.15 KFH41706.1 - 5.6e-17 61.9 4.7 1.4e-16 60.6 3.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 KFH41706.1 - 0.014 15.2 3.2 0.019 14.8 3.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 KFH41707.1 - 3.4e-31 106.8 29.3 4.5e-05 24.1 0.1 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41707.1 - 2e-17 63.2 5.2 0.0001 22.5 0.0 5.5 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH41707.1 - 9.1e-05 21.6 2.6 1.2 8.0 0.1 4.5 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFH41707.1 - 0.00018 21.3 1.7 0.35 10.9 0.1 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KFH41707.1 - 0.014 14.7 0.0 3.4 6.9 0.0 2.8 1 1 1 2 2 2 0 WD40-like domain MRP-S28 PF10213.9 KFH41708.1 - 4.7e-47 159.6 0.4 7.9e-47 158.8 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein LTXXQ PF07813.12 KFH41708.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.3 3 0 0 3 3 3 0 LTXXQ motif family protein SIS PF01380.22 KFH41709.1 - 1e-13 51.3 0.0 2.8e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KFH41709.1 - 0.0013 18.8 0.0 1.1 9.3 0.0 2.4 1 1 1 2 2 2 2 SIS domain ECR1_N PF14382.6 KFH41710.1 - 4.4e-14 52.0 0.4 8.8e-14 51.0 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KFH41710.1 - 4.4e-06 26.9 0.1 1e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KFH41710.1 - 0.026 15.1 1.3 0.41 11.3 0.1 2.6 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 Fungal_trans PF04082.18 KFH41711.1 - 1.2e-05 24.5 0.0 2.6e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41711.1 - 1.3e-05 25.2 14.2 2.5e-05 24.3 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.21 KFH41712.1 - 1.4e-66 224.6 0.0 1.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFH41712.1 - 0.0006 19.8 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.25 KFH41714.1 - 2.2e-23 82.8 0.1 4.3e-23 81.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH41714.1 - 1.4e-13 51.0 0.1 2.3e-13 50.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH41714.1 - 0.00087 18.8 0.0 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFH41714.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain DAO PF01266.24 KFH41715.1 - 2.2e-11 44.0 0.0 3.6e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH41715.1 - 0.11 11.6 0.0 9.5 5.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DUF4660 PF15559.6 KFH41715.1 - 0.11 12.8 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Fungal_trans PF04082.18 KFH41716.1 - 2.7e-12 46.3 0.2 8e-12 44.7 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41716.1 - 3.5e-06 27.0 9.7 9.1e-06 25.7 9.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KFH41716.1 - 0.043 14.0 2.1 0.096 12.9 0.5 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain Sulfotransfer_4 PF17784.1 KFH41717.1 - 5.9e-07 29.5 0.0 6.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sugar_tr PF00083.24 KFH41718.1 - 1.8e-64 218.3 21.9 2.1e-64 218.1 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH41718.1 - 1.2e-08 34.3 26.9 1.2e-08 34.3 26.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH41718.1 - 0.096 11.5 10.8 0.0068 15.3 4.4 2.1 2 0 0 2 2 2 0 MFS_1 like family UNC-93 PF05978.16 KFH41718.1 - 0.1 12.3 7.5 0.019 14.7 2.6 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFH41719.1 - 1.1e-12 47.5 35.0 1.1e-12 47.5 35.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFH41719.1 - 1.6e-10 40.9 4.9 1.6e-10 40.9 4.9 3.1 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ycf4 PF02392.16 KFH41719.1 - 0.54 9.8 2.5 1.2 8.7 2.5 1.5 1 0 0 1 1 1 0 Ycf4 DUF3169 PF11368.8 KFH41719.1 - 1.5 8.3 0.0 1.5 8.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3169) DUF1129 PF06570.11 KFH41719.1 - 3.5 7.1 8.2 0.22 11.0 0.5 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1129) DUF2749 PF10907.8 KFH41720.1 - 0.14 12.4 0.4 0.24 11.6 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) TPR_12 PF13424.6 KFH41722.1 - 1.9e-20 72.9 2.8 8.5e-10 38.8 0.2 4.6 3 1 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KFH41722.1 - 5.6e-16 58.5 0.0 7.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KFH41722.1 - 2.3e-11 43.0 3.2 0.019 15.2 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH41722.1 - 2.8e-11 42.6 6.3 0.092 12.9 1.8 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH41722.1 - 5.6e-09 35.6 5.4 0.42 10.6 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFH41722.1 - 6.2e-09 35.3 4.2 0.00064 19.4 0.7 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH41722.1 - 3.7e-08 33.5 14.7 0.24 12.3 1.1 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH41722.1 - 2.4e-07 30.3 1.9 2.6 8.3 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH41722.1 - 1.1e-06 28.3 0.7 0.007 15.8 0.3 2.4 1 1 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KFH41722.1 - 4.6e-06 27.2 9.8 0.024 15.3 0.0 4.9 3 2 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFH41722.1 - 8.2e-06 26.3 0.6 0.0002 21.8 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KFH41722.1 - 5.5e-05 23.6 6.5 0.13 12.8 0.1 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat ATPase_2 PF01637.18 KFH41722.1 - 0.0014 18.6 0.2 0.015 15.2 0.0 2.7 1 1 2 3 3 3 1 ATPase domain predominantly from Archaea ANAPC3 PF12895.7 KFH41722.1 - 0.0017 18.5 0.5 1 9.7 0.1 3.4 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFH41722.1 - 0.081 13.6 0.7 0.081 13.6 0.7 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFH41722.1 - 0.086 12.0 0.2 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH41722.1 - 0.086 13.5 7.5 23 5.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFH41722.1 - 0.48 10.1 4.6 1.9 8.3 0.6 3.1 2 1 1 3 3 3 0 TPR repeat Copper-bind PF00127.20 KFH41723.1 - 0.049 14.1 0.0 0.053 14.0 0.0 1.1 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Fungal_trans_2 PF11951.8 KFH41725.1 - 1.5e-24 86.5 1.4 1.4e-19 70.1 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41725.1 - 8.3e-07 29.0 6.3 1.6e-06 28.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KFH41726.1 - 4.3e-08 33.6 0.1 7.6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 KFH41728.1 - 8.4e-07 29.0 0.0 2.5e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH41728.1 - 0.0013 18.6 0.1 0.038 13.9 0.0 2.8 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 KFH41728.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family YqgF PF14639.6 KFH41729.1 - 0.037 13.8 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Pkinase PF00069.25 KFH41730.1 - 1.6e-16 60.5 0.0 5.4e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41730.1 - 0.00022 20.6 0.0 0.00064 19.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase zf-C2H2_4 PF13894.6 KFH41731.1 - 1.1e-13 50.8 23.8 0.29 12.1 0.1 7.5 6 1 1 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 KFH41731.1 - 1.2e-13 50.9 22.2 0.00016 21.9 3.5 5.9 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFH41731.1 - 1.3e-11 44.4 22.7 0.0011 19.2 0.2 5.2 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFH41731.1 - 2e-10 40.6 32.4 0.18 12.3 0.3 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KFH41731.1 - 8.5e-10 38.9 21.0 0.079 13.3 2.3 6.1 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFH41731.1 - 9.3e-06 25.5 30.4 0.0053 16.7 0.1 6.3 8 0 0 8 8 8 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH41731.1 - 0.00012 22.3 26.9 1.5 9.4 0.2 6.5 6 0 0 6 6 6 3 Zinc-finger double domain HypA PF01155.19 KFH41731.1 - 0.0045 17.0 7.6 0.07 13.2 0.2 3.4 2 2 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_ZIC PF18366.1 KFH41731.1 - 0.013 15.5 11.4 0.75 10.0 0.1 4.8 5 0 0 5 5 5 0 Zic proteins zinc finger domain AKAP95 PF04988.12 KFH41731.1 - 0.018 15.3 5.7 3.3 7.9 0.2 3.6 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-Di19 PF05605.12 KFH41731.1 - 0.054 13.8 0.4 0.054 13.8 0.4 4.3 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.11 KFH41731.1 - 0.49 10.8 2.6 0.77 10.1 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Elf1 PF05129.13 KFH41731.1 - 0.88 9.7 0.1 0.88 9.7 0.1 4.1 3 2 2 5 5 5 0 Transcription elongation factor Elf1 like zf-RRPl_C4 PF17026.5 KFH41731.1 - 1.6 8.9 7.1 11 6.2 4.6 2.9 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KFH41731.1 - 2.9 8.1 23.1 11 6.2 0.4 5.7 5 1 0 5 5 4 0 Zinc ribbon domain zf-3CxxC PF13695.6 KFH41731.1 - 5 7.6 10.6 0.81 10.2 3.3 3.0 2 2 1 3 3 3 0 Zinc-binding domain zf-B_box PF00643.24 KFH41731.1 - 9.5 6.5 12.7 0.96 9.7 0.5 4.4 5 0 0 5 5 5 0 B-box zinc finger RasGEF PF00617.19 KFH41732.1 - 1.4e-51 175.3 0.2 2.7e-51 174.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFH41732.1 - 4.5e-15 55.8 0.0 1.5e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KFH41732.1 - 1.7e-06 27.8 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFH41732.1 - 4e-05 23.1 0.0 9.1e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain DUF3053 PF11254.8 KFH41732.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) HWE_HK PF07536.14 KFH41732.1 - 0.39 11.5 2.2 28 5.5 0.5 3.2 2 0 0 2 2 2 0 HWE histidine kinase ADH_zinc_N_2 PF13602.6 KFH41733.1 - 1.8e-28 100.3 0.0 2.9e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH41733.1 - 7.2e-20 71.3 1.3 3.3e-19 69.1 1.2 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase SDH_sah PF01972.16 KFH41733.1 - 0.0025 16.9 0.1 0.0065 15.5 0.0 1.7 3 0 0 3 3 3 1 Serine dehydrogenase proteinase PALP PF00291.25 KFH41733.1 - 0.04 13.3 0.2 0.061 12.7 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KFH41733.1 - 0.085 12.3 0.7 0.17 11.3 0.7 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Cnn_1N PF07989.11 KFH41734.1 - 2e-10 40.7 11.2 1.3e-09 38.0 9.1 2.5 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KFH41734.1 - 1.3 9.1 8.8 2 8.5 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fes1 PF08609.10 KFH41734.1 - 6.2 7.8 10.6 11 6.9 0.0 3.9 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 bZIP_1 PF00170.21 KFH41734.1 - 7.6 6.7 14.0 4.4 7.5 5.0 3.5 2 1 1 3 3 3 0 bZIP transcription factor PRKCSH PF07915.13 KFH41736.1 - 1.2e-17 64.7 0.3 2.8e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Glycos_transf_1 PF00534.20 KFH41737.1 - 5.1e-19 68.5 0.0 5.2e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH41737.1 - 3e-14 53.6 0.0 2.4e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFH41737.1 - 4.1e-05 23.9 0.0 0.00012 22.4 0.0 1.8 1 1 1 2 2 2 1 Glycosyl transferases group 1 Utp12 PF04003.12 KFH41738.1 - 3.8e-25 88.3 0.2 8.1e-25 87.2 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family MMS19_C PF12460.8 KFH41738.1 - 0.33 10.0 2.4 0.19 10.8 0.2 1.6 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal SDA1 PF05285.12 KFH41738.1 - 0.36 10.2 36.7 0.21 11.0 3.9 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 KFH41738.1 - 3.2 5.8 36.9 0.32 9.2 22.5 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KFH41738.1 - 7.1 5.9 27.9 1.9 7.7 2.2 2.1 2 0 0 2 2 2 0 BUD22 zf-C2H2_4 PF13894.6 KFH41740.1 - 1.5 9.9 3.1 1.7 9.7 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger AA_permease PF00324.21 KFH41741.1 - 4.6e-100 335.5 40.7 5.2e-100 335.3 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH41741.1 - 2.3e-26 92.6 43.0 2.8e-26 92.3 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease HSP70 PF00012.20 KFH41742.1 - 5.4e-11 41.4 0.1 3.9e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 KFH41742.1 - 0.004 17.6 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA NUDIX PF00293.28 KFH41743.1 - 5.2e-07 29.8 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KFH41743.1 - 0.052 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) His_Phos_2 PF00328.22 KFH41744.1 - 2.8e-31 109.2 0.0 3.8e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sld5 PF05916.11 KFH41745.1 - 2.1e-14 53.9 0.0 2.7e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Lipase_GDSL PF00657.22 KFH41746.1 - 1.3e-06 28.6 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sod_Fe_C PF02777.18 KFH41747.1 - 7.5e-35 119.2 0.3 1.4e-34 118.4 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFH41747.1 - 3.4e-31 107.6 0.5 6.3e-31 106.7 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribonuclease PF00545.20 KFH41748.1 - 1.7e-05 25.4 0.0 2.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Bromodomain PF00439.25 KFH41749.1 - 6.8e-31 106.2 0.1 9.6e-16 57.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFH41749.1 - 2.2e-13 50.2 0.9 4.7e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SelK_SelG PF10961.8 KFH41749.1 - 0.032 14.9 3.9 0.085 13.5 3.9 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DPBB_1 PF03330.18 KFH41751.1 - 1.9e-07 31.3 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KFH41751.1 - 0.0019 18.1 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family MFS_1 PF07690.16 KFH41752.1 - 2.2e-29 102.5 23.9 1.1e-27 96.9 26.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFH41753.1 - 7.9e-55 186.0 0.0 1.2e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41753.1 - 2.3e-30 105.8 0.0 1.1e-28 100.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH41753.1 - 0.0043 16.0 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFH41753.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFH41753.1 - 0.14 11.5 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 KFH41754.1 - 0.00016 22.1 0.0 0.0005 20.5 0.0 1.7 2 0 0 2 2 2 1 SET domain Zip PF02535.22 KFH41755.1 - 1.6e-33 116.4 19.4 3.4e-26 92.3 13.7 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter Methyltransf_23 PF13489.6 KFH41758.1 - 9.6e-15 54.8 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH41758.1 - 5.1e-10 39.9 0.0 9.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH41758.1 - 1e-07 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41758.1 - 1.5e-07 32.0 0.0 3.5e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFH41758.1 - 3.8e-05 23.1 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_11 PF08241.12 KFH41758.1 - 0.00023 21.7 0.0 0.00042 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFH41758.1 - 0.00099 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFH41758.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFH41758.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFH41758.1 - 0.033 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KFH41758.1 - 0.09 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KFH41758.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KFH41758.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KFH41758.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CAP_N PF01213.19 KFH41758.1 - 1.9 7.9 4.7 3.7 7.0 4.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Brix PF04427.18 KFH41759.1 - 1e-24 87.7 0.0 1.4e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain RRN3 PF05327.11 KFH41759.1 - 2.9 6.3 5.6 4.1 5.8 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_6 PF12697.7 KFH41761.1 - 6.6e-16 59.6 4.4 9.1e-16 59.1 4.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH41761.1 - 1.6e-06 27.6 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH41761.1 - 3.7e-05 23.5 0.0 0.00012 21.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold ZF-HD_dimer PF04770.12 KFH41761.1 - 0.12 12.7 0.0 7.8 6.9 0.0 2.2 2 0 0 2 2 2 0 ZF-HD protein dimerisation region NOC3p PF07540.11 KFH41762.1 - 1.1e-30 105.9 0.9 9.9e-29 99.7 0.1 3.2 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KFH41762.1 - 2e-26 93.1 0.2 2e-26 93.1 0.2 2.3 2 1 0 2 2 2 1 CBF/Mak21 family Pep3_Vps18 PF05131.14 KFH41763.1 - 2e-43 147.7 0.1 7.3e-43 145.9 0.0 2.0 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFH41763.1 - 1.9e-11 44.0 5.2 1.8e-07 31.1 0.0 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 KFH41763.1 - 1.7e-05 25.0 1.8 0.0011 19.2 0.1 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 KFH41763.1 - 0.002 18.0 0.5 0.002 18.0 0.5 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH41763.1 - 0.004 17.0 0.9 0.01 15.6 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFH41763.1 - 0.0097 15.5 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KFH41763.1 - 0.013 15.5 0.2 0.033 14.2 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFH41763.1 - 0.018 15.4 0.7 0.046 14.1 0.7 1.7 1 0 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.9 KFH41763.1 - 0.054 13.9 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 KFH41763.1 - 0.079 13.3 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFH41763.1 - 0.28 11.1 0.7 1 9.3 0.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH41763.1 - 0.47 10.2 8.7 0.025 14.3 2.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KFH41763.1 - 3.3 7.8 9.1 0.11 12.5 2.3 2.0 3 0 0 3 3 3 0 Zinc-finger 2OG-FeII_Oxy_3 PF13640.6 KFH41765.1 - 9.9e-09 36.0 0.3 2.4e-08 34.8 0.3 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Osteopontin PF00865.18 KFH41766.1 - 0.019 14.5 4.2 0.025 14.1 4.2 1.1 1 0 0 1 1 1 0 Osteopontin DUF2791 PF10923.8 KFH41766.1 - 0.026 13.4 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Baculo_PEP_C PF04513.12 KFH41766.1 - 0.069 13.2 0.9 0.2 11.7 0.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus REF PF05755.12 KFH41766.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) YtxH PF12732.7 KFH41766.1 - 9.1 6.9 6.4 1.5 9.4 0.0 2.6 2 1 0 2 2 2 0 YtxH-like protein CRIM PF16978.5 KFH41767.1 - 4.6e-45 153.2 0.0 1.1e-44 152.0 0.0 1.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KFH41767.1 - 8.7e-30 103.2 0.0 1.8e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KFH41767.1 - 0.00057 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KFH41767.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain TFIIF_alpha PF05793.12 KFH41767.1 - 7.3 5.1 19.0 0.0084 14.8 7.2 2.0 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KFH41767.1 - 7.6 7.0 12.3 0.47 10.9 3.6 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.9 KFH41768.1 - 4.6e-32 112.5 21.3 4.2e-31 109.4 21.3 2.9 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting GDP_Man_Dehyd PF16363.5 KFH41770.1 - 2.3e-69 234.4 0.0 2.6e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFH41770.1 - 1.7e-59 201.3 0.0 2.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFH41770.1 - 4.4e-24 85.1 0.0 6e-23 81.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFH41770.1 - 2.6e-21 75.9 0.0 3.4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFH41770.1 - 7.8e-20 71.1 0.0 9.3e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFH41770.1 - 1.6e-17 63.5 0.4 4.1e-16 58.9 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFH41770.1 - 2.8e-07 30.6 0.0 6.3e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KFH41770.1 - 0.012 15.1 0.0 1.4 8.3 0.1 2.8 3 0 0 3 3 3 0 short chain dehydrogenase AMP-binding PF00501.28 KFH41771.1 - 4.6e-73 246.2 0.0 6.8e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KFH41771.1 - 5.3e-63 212.6 0.0 8e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFH41771.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFH41771.1 - 7.7e-07 29.4 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KFH41771.1 - 4.6e-06 26.6 0.0 3e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFH41771.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KFH41771.1 - 0.0014 19.6 1.0 0.015 16.3 0.0 3.2 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KFH41771.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HsbA PF12296.8 KFH41772.1 - 4.5e-28 98.1 3.6 4.5e-28 98.1 3.6 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Aldedh PF00171.22 KFH41773.1 - 1.5e-161 538.0 0.0 1.7e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFH41773.1 - 0.2 11.1 0.0 0.89 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ras PF00071.22 KFH41774.1 - 1.3e-22 80.1 0.0 1.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH41774.1 - 0.19 11.9 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_C PF00137.21 KFH41775.1 - 1.9e-27 95.4 27.0 2.3e-20 72.7 13.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KFH41775.1 - 1.1 8.5 5.4 0.82 9.0 0.7 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TCR_zetazeta PF11628.8 KFH41775.1 - 9.7 6.0 8.2 14 5.4 0.3 2.8 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain Asp PF00026.23 KFH41776.1 - 7.1e-67 226.1 0.0 1.8e-66 224.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH41776.1 - 8.6e-11 42.4 0.5 2.3e-09 37.8 0.5 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFH41776.1 - 0.017 15.8 1.3 11 6.7 0.0 3.7 4 0 0 4 4 4 0 Aspartyl protease TAXi_C PF14541.6 KFH41776.1 - 0.05 13.4 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Fungal_trans PF04082.18 KFH41777.1 - 1.6e-12 47.0 0.0 2.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41777.1 - 7e-10 38.9 10.6 7e-10 38.9 10.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KFH41777.1 - 5.7 7.5 10.7 7.9 7.1 6.2 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF3990 PF13151.6 KFH41778.1 - 0.0035 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) DUF1749 PF08538.10 KFH41779.1 - 5.7e-84 281.7 0.0 6.9e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KFH41779.1 - 1.9e-09 38.5 0.0 2.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH41779.1 - 8.5e-07 28.5 0.0 1.2e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH41779.1 - 0.0014 18.3 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KFH41779.1 - 0.0039 17.1 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 KFH41779.1 - 0.075 13.1 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KFH41779.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 KFH41780.1 - 1.8e-37 129.2 0.0 2.6e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41780.1 - 1.9e-26 92.9 0.0 3.9e-26 91.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFH41780.1 - 0.0017 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFH41780.1 - 0.0044 16.4 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH41780.1 - 0.047 13.6 0.0 6.7 6.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family NUDIX PF00293.28 KFH41781.1 - 5.1e-17 62.2 0.1 9.6e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KFH41781.1 - 5.1e-14 52.8 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KFH41781.1 - 0.0001 21.9 0.2 0.00021 20.9 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.24 KFH41782.1 - 9.2e-48 163.2 0.6 1e-47 163.0 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 KFH41783.1 - 2.1e-68 230.5 0.0 3.8e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41783.1 - 6.4e-49 166.6 0.0 1.2e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KFH41783.1 - 8.6e-28 96.6 0.0 1.7e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KFH41783.1 - 2.9e-17 62.5 0.3 1.9e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFH41783.1 - 9.4e-16 58.0 0.1 1.8e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFH41783.1 - 6e-14 52.4 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KFH41783.1 - 4.5e-07 29.5 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFH41783.1 - 0.015 14.1 0.0 0.033 12.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SAM_4 PF18017.1 KFH41783.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFH41783.1 - 0.036 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain GGACT PF06094.12 KFH41784.1 - 5e-07 30.4 0.1 7.4e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KFH41784.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family NB-ARC PF00931.22 KFH41785.1 - 0.0085 15.3 0.0 0.0096 15.1 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFH41785.1 - 0.023 15.1 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KFH41785.1 - 0.096 12.7 0.3 0.13 12.4 0.3 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KFH41785.1 - 0.17 11.3 0.2 0.23 10.9 0.2 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Sulfotransfer_3 PF13469.6 KFH41787.1 - 0.00019 21.9 0.4 0.011 16.1 0.0 2.4 3 0 0 3 3 3 2 Sulfotransferase family PQ-loop PF04193.14 KFH41788.1 - 1.6e-37 127.1 13.1 4.2e-19 68.1 1.7 2.7 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 KFH41788.1 - 0.36 10.4 0.9 0.56 9.8 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain Cytochrom_C_asm PF01578.20 KFH41788.1 - 0.67 9.7 6.8 7 6.4 0.7 2.3 2 0 0 2 2 2 0 Cytochrome C assembly protein LON_substr_bdg PF02190.16 KFH41790.1 - 6.1e-29 101.4 0.0 8.8e-29 100.9 0.0 1.2 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain NCBP3 PF10309.9 KFH41790.1 - 0.0091 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 PIG-X PF08320.12 KFH41791.1 - 2.2e-64 217.3 0.0 3.2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 CoaE PF01121.20 KFH41792.1 - 1.1e-40 139.2 0.0 3.7e-40 137.5 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFH41792.1 - 0.0085 16.6 0.4 0.37 11.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain WD40 PF00400.32 KFH41794.1 - 3.9e-11 43.3 0.1 0.27 12.2 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KFH41794.1 - 0.079 13.5 1.1 26 5.5 0.7 3.4 3 0 0 3 3 3 0 PQQ-like domain HEAT_2 PF13646.6 KFH41795.1 - 0.00048 20.5 10.3 1.4 9.4 0.2 5.6 7 1 0 7 7 7 3 HEAT repeats UTP15_C PF09384.10 KFH41795.1 - 0.042 13.5 0.1 7.2 6.3 0.0 2.9 2 0 0 2 2 2 0 UTP15 C terminal RTP1_C1 PF10363.9 KFH41795.1 - 0.045 13.9 0.1 0.48 10.6 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KFH41795.1 - 0.11 12.5 2.6 13 5.8 0.0 3.7 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFH41795.1 - 0.14 12.5 3.2 37 4.9 0.3 5.5 6 0 0 6 6 6 0 HEAT repeat DUF2682 PF10909.8 KFH41795.1 - 0.74 10.3 3.0 5.8 7.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) ABC_membrane PF00664.23 KFH41796.1 - 2e-82 277.0 38.3 2.7e-48 165.0 9.4 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH41796.1 - 7.3e-53 178.8 0.1 1.3e-30 106.7 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH41796.1 - 2.6e-10 40.1 3.5 0.017 14.5 0.1 4.4 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 KFH41796.1 - 1.7e-06 27.7 5.4 1.7e-06 27.7 5.4 2.1 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_16 PF13191.6 KFH41796.1 - 3.5e-06 27.5 0.5 0.074 13.4 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFH41796.1 - 1.9e-05 24.7 0.4 0.18 11.9 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFH41796.1 - 2.7e-05 24.8 0.3 0.006 17.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFH41796.1 - 5.6e-05 23.1 0.1 0.12 12.2 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KFH41796.1 - 5.7e-05 23.1 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH41796.1 - 0.00014 21.5 0.3 0.83 9.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KFH41796.1 - 0.00033 20.8 1.2 0.91 9.6 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 KFH41796.1 - 0.00068 19.4 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFH41796.1 - 0.027 14.8 1.5 11 6.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFH41796.1 - 0.075 12.7 1.1 3.4 7.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KFH41796.1 - 0.078 13.2 1.0 12 6.1 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KFH41796.1 - 0.083 12.6 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUP PF00674.18 KFH41796.1 - 0.13 12.5 1.8 0.53 10.4 1.8 2.1 1 0 0 1 1 1 0 DUP family cobW PF02492.19 KFH41796.1 - 0.13 11.8 0.9 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KFH41796.1 - 0.14 12.2 4.2 2.3 8.3 0.0 3.0 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.22 KFH41796.1 - 0.15 12.4 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MWFE PF15879.5 KFH41796.1 - 0.16 12.2 0.6 0.91 9.7 0.6 2.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit ATP_bind_1 PF03029.17 KFH41796.1 - 0.25 11.1 2.8 15 5.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zn_clus PF00172.18 KFH41797.1 - 3.9e-09 36.5 5.9 6.7e-09 35.7 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41797.1 - 0.0035 16.4 0.1 0.045 12.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain NinF PF05810.12 KFH41797.1 - 2.7 7.9 4.7 6.2 6.8 4.7 1.5 1 0 0 1 1 1 0 NinF protein PDT PF00800.18 KFH41798.1 - 7.4e-60 201.9 0.0 9.3e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KFH41798.1 - 1.1e-07 31.5 0.0 2.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KFH41798.1 - 0.084 13.5 0.0 8.5 7.0 0.0 2.4 2 0 0 2 2 2 0 ACT domain Nuc_deoxyri_tr2 PF15891.5 KFH41800.1 - 2.9e-35 120.8 0.0 3.8e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like DUF2057 PF09829.9 KFH41801.1 - 0.69 10.1 4.8 1.6 8.9 4.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Tim17 PF02466.19 KFH41802.1 - 3.4e-24 85.3 5.8 3.4e-24 85.3 5.8 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Metallophos_2 PF12850.7 KFH41803.1 - 6.5e-10 39.4 0.0 2.7e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFH41803.1 - 3.5e-09 37.5 0.0 6.5e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mhr1 PF12829.7 KFH41805.1 - 4e-31 106.9 0.0 6.7e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination NEMP PF10225.9 KFH41805.1 - 0.049 13.3 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 NEMP family AAA_2 PF07724.14 KFH41807.1 - 1e-46 159.2 0.0 7.9e-45 153.0 0.0 3.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFH41807.1 - 6.8e-33 112.7 3.8 6.8e-33 112.7 3.8 3.6 3 1 1 4 4 3 1 AAA lid domain AAA PF00004.29 KFH41807.1 - 2e-27 96.2 0.0 8.6e-15 55.3 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFH41807.1 - 4.3e-24 84.4 0.7 2.5e-23 81.9 0.7 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFH41807.1 - 8.7e-16 58.2 0.0 5.9e-10 39.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH41807.1 - 1.2e-12 48.3 0.0 4.5e-05 23.8 0.0 4.0 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KFH41807.1 - 1.9e-10 41.4 14.7 7.1e-07 29.8 0.1 5.2 4 3 0 4 4 2 2 AAA ATPase domain Sigma54_activat PF00158.26 KFH41807.1 - 3.4e-09 36.6 0.0 4.7e-06 26.4 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 KFH41807.1 - 2.5e-07 30.8 0.0 0.033 14.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFH41807.1 - 3.5e-06 26.8 0.0 0.078 12.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFH41807.1 - 4e-06 27.4 3.5 0.04 14.4 0.0 4.5 4 1 0 4 4 3 2 AAA domain AAA_7 PF12775.7 KFH41807.1 - 4.3e-06 26.4 0.0 0.019 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KFH41807.1 - 6.5e-06 26.2 6.5 0.026 14.5 0.2 4.8 3 2 2 6 6 6 2 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFH41807.1 - 7.5e-06 26.2 0.1 0.26 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFH41807.1 - 8.8e-06 25.2 0.1 0.29 10.5 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFH41807.1 - 3.7e-05 24.1 0.0 0.51 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFH41807.1 - 3.9e-05 23.9 0.2 0.45 10.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain Clp_N PF02861.20 KFH41807.1 - 7.1e-05 22.9 6.0 0.00027 21.0 0.4 4.0 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component TsaE PF02367.17 KFH41807.1 - 0.00015 21.7 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KFH41807.1 - 0.00017 21.4 1.7 2 8.2 0.7 4.6 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KFH41807.1 - 0.0003 20.8 0.7 0.28 11.1 0.0 3.3 3 0 0 3 3 2 1 RsgA GTPase AAA_24 PF13479.6 KFH41807.1 - 0.00032 20.5 0.1 0.46 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KFH41807.1 - 0.00035 20.3 0.0 1.4 8.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KFH41807.1 - 0.00038 20.3 0.1 1.7 8.5 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFH41807.1 - 0.00047 20.7 0.4 0.85 10.1 0.0 3.5 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 KFH41807.1 - 0.00083 18.5 1.5 0.024 13.7 0.5 3.0 2 1 0 2 2 2 1 Type II/IV secretion system protein Torsin PF06309.11 KFH41807.1 - 0.0011 19.0 0.0 0.0091 16.1 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_19 PF13245.6 KFH41807.1 - 0.0012 19.2 1.6 0.32 11.3 0.1 3.8 5 1 0 6 6 2 1 AAA domain NACHT PF05729.12 KFH41807.1 - 0.002 18.0 0.1 0.16 11.9 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 KFH41807.1 - 0.0037 16.6 0.0 0.86 8.8 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 KFH41807.1 - 0.0045 16.7 0.0 4.5 7.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KFH41807.1 - 0.0056 16.9 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KFH41807.1 - 0.0073 16.2 0.0 0.23 11.4 0.0 3.0 3 0 0 3 3 2 1 NTPase ResIII PF04851.15 KFH41807.1 - 0.011 15.7 0.0 2.2 8.2 0.0 3.7 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 KFH41807.1 - 0.012 15.5 0.3 11 5.8 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 KFH41807.1 - 0.018 14.7 0.0 5.5 6.6 0.0 3.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 KFH41807.1 - 0.021 14.0 0.1 1.8 7.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) CbiA PF01656.23 KFH41807.1 - 0.055 13.5 0.1 40 4.3 0.0 3.8 4 1 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KFH41807.1 - 0.063 13.1 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KFH41807.1 - 0.092 12.5 0.0 7.2 6.3 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 KFH41807.1 - 0.096 11.6 0.6 8.7 5.2 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 KFH41807.1 - 0.097 12.2 3.2 4.1 6.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KFH41807.1 - 0.2 12.1 0.0 0.2 12.1 0.0 4.5 5 1 0 5 5 2 0 AAA domain Antigen_Bd37 PF11641.8 KFH41807.1 - 0.66 9.4 6.1 0.32 10.5 2.4 2.1 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Cob_adeno_trans PF01923.18 KFH41807.1 - 0.85 9.7 8.6 0.68 10.1 2.6 3.3 3 0 0 3 3 3 0 Cobalamin adenosyltransferase KTI12 PF08433.10 KFH41807.1 - 1.1 8.6 5.8 9.9 5.5 0.0 3.9 4 0 0 4 4 4 0 Chromatin associated protein KTI12 Macoilin PF09726.9 KFH41807.1 - 1.4 7.4 7.7 2.8 6.4 7.7 1.4 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 KFH41807.1 - 3.3 5.5 8.1 0.13 10.1 2.5 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Homeobox_KN PF05920.11 KFH41808.1 - 3.8e-19 68.3 0.1 1.5e-18 66.4 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFH41808.1 - 0.00051 19.8 4.2 0.011 15.6 4.2 2.4 1 1 0 1 1 1 1 Homeodomain INSIG PF07281.12 KFH41809.1 - 2.4e-69 233.2 0.9 3e-69 232.9 0.9 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) FAD-oxidase_C PF02913.19 KFH41810.1 - 1.2e-61 208.6 0.6 2.6e-61 207.4 0.1 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFH41810.1 - 1.4e-35 122.0 0.0 2.9e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain zf-Tim10_DDP PF02953.15 KFH41811.1 - 3.1e-20 71.6 1.6 3.7e-20 71.3 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mg_trans_NIPA PF05653.14 KFH41812.1 - 3.1e-86 289.2 26.0 4e-86 288.8 26.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFH41812.1 - 3.6e-05 24.0 7.5 3.6e-05 24.0 7.5 3.2 3 0 0 3 3 3 1 EamA-like transporter family Zein-binding PF04576.15 KFH41812.1 - 0.12 12.7 1.1 0.22 11.8 1.1 1.4 1 0 0 1 1 1 0 Zein-binding ST7 PF04184.12 KFH41812.1 - 1.4 7.3 3.2 2.4 6.5 3.2 1.3 1 0 0 1 1 1 0 ST7 protein MFS_1 PF07690.16 KFH41813.1 - 7.7e-20 71.1 53.1 9.8e-18 64.2 52.0 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KFH41813.1 - 0.086 11.1 7.4 0.021 13.1 2.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ECH_1 PF00378.20 KFH41814.1 - 7.9e-39 133.5 0.0 9.9e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH41814.1 - 2e-21 76.9 0.0 5.1e-19 68.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CDC45 PF02724.14 KFH41815.1 - 0.00052 18.5 3.8 0.00067 18.1 3.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Aldedh PF00171.22 KFH41816.1 - 2.3e-139 464.9 0.0 2.7e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF966 PF06136.13 KFH41817.1 - 0.68 9.6 15.6 0.78 9.4 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.6 KFH41817.1 - 1.1 9.8 25.2 1.5 9.3 25.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SMYLE_N PF18615.1 KFH41817.1 - 1.3 8.5 11.0 1.8 8.0 11.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain ORC6 PF05460.13 KFH41817.1 - 1.6 7.9 19.5 2.1 7.6 19.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPX PF03105.19 KFH41817.1 - 2.4 8.0 25.1 4 7.3 25.1 1.3 1 0 0 1 1 1 0 SPX domain CDK5_activator PF03261.15 KFH41817.1 - 2.9 7.3 10.6 3.7 7.0 10.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PPP4R2 PF09184.11 KFH41817.1 - 5.1 6.6 9.0 6.6 6.2 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 Med3 PF11593.8 KFH41817.1 - 7.3 5.7 23.9 10 5.2 23.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 KFH41817.1 - 7.8 6.4 24.3 10 6.0 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 KFH41817.1 - 7.9 5.0 26.3 9.6 4.7 26.3 1.0 1 0 0 1 1 1 0 Hamartin protein QCR10 PF09796.9 KFH41818.1 - 6.3e-24 83.8 0.0 6.7e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SbcCD_C PF13558.6 KFH41819.1 - 3.3e-06 27.2 0.4 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit COG2 PF06148.11 KFH41819.1 - 8.1e-05 22.7 0.6 8.1e-05 22.7 0.6 9.5 3 2 7 11 11 11 4 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 KFH41819.1 - 0.0013 17.5 14.7 0.0013 17.5 14.7 6.5 1 1 5 6 6 6 3 AAA domain Exonuc_VII_S PF02609.16 KFH41819.1 - 0.0026 17.8 0.4 0.0026 17.8 0.4 5.9 6 0 0 6 6 6 1 Exonuclease VII small subunit FliJ PF02050.16 KFH41819.1 - 0.007 16.6 0.2 0.007 16.6 0.2 11.0 4 3 5 11 11 11 4 Flagellar FliJ protein Methyltransf_25 PF13649.6 KFH41819.1 - 3.1 8.6 5.9 7.5 7.3 0.1 4.5 5 0 0 5 5 5 0 Methyltransferase domain CENP-B_dimeris PF09026.10 KFH41820.1 - 0.11 12.9 24.9 0.25 11.8 9.5 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Macoilin PF09726.9 KFH41820.1 - 0.16 10.5 8.1 0.2 10.2 8.1 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KFH41820.1 - 1.3 6.8 6.3 1.3 6.7 6.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 KFH41820.1 - 2.5 6.1 12.7 3.3 5.7 0.3 2.0 2 0 0 2 2 2 0 DNA polymerase phi PPP4R2 PF09184.11 KFH41820.1 - 8 6.0 16.5 4.8 6.7 8.6 2.0 2 0 0 2 2 2 0 PPP4R2 DUF2796 PF10986.8 KFH41820.1 - 8.3 6.3 19.2 0.7 9.8 13.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Cwf_Cwc_15 PF04889.12 KFH41820.1 - 8.8 6.0 22.4 4.2 7.0 2.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KFH41820.1 - 9.7 5.4 14.0 13 4.9 14.0 1.2 1 0 0 1 1 1 0 BUD22 PAS_3 PF08447.12 KFH41821.1 - 1.4e-16 60.6 0.0 2.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 KFH41821.1 - 3.4e-16 58.5 6.1 6.2e-16 57.7 6.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KFH41821.1 - 2.7e-09 37.0 0.0 5.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFH41821.1 - 1.5e-05 25.2 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFH41821.1 - 8.7e-05 22.7 0.0 0.00036 20.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 KFH41821.1 - 0.0077 16.3 0.2 0.015 15.4 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain PAS_11 PF14598.6 KFH41821.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.12 KFH41821.1 - 0.13 11.8 0.9 0.76 9.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 KFH41821.1 - 2.6 8.0 6.2 0.66 10.0 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) PPP4R2 PF09184.11 KFH41822.1 - 7.5e-09 35.6 6.8 7.5e-09 35.6 6.8 3.3 2 1 0 2 2 2 1 PPP4R2 EMP70 PF02990.16 KFH41823.1 - 6.5e-207 688.3 3.5 6.5e-207 688.3 3.5 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 DHO_dh PF01180.21 KFH41824.1 - 1.7e-65 221.2 0.0 2.2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KFH41824.1 - 0.00079 18.6 1.0 0.035 13.2 1.1 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 KFH41824.1 - 0.0074 15.8 1.3 1.6 8.1 0.1 2.3 2 0 0 2 2 2 2 PcrB family DUF5470 PF17564.2 KFH41824.1 - 0.087 13.0 1.6 0.19 12.0 1.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Selenoprotein_S PF06936.11 KFH41825.1 - 0.7 9.7 9.5 1.3 8.8 9.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Hid1 PF12722.7 KFH41825.1 - 9.4 4.2 7.6 16 3.4 7.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPRY PF00622.28 KFH41826.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Spt20 PF12090.8 KFH41826.1 - 3.1 7.3 8.1 4.4 6.9 8.1 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KFH41826.1 - 5.8 6.8 10.4 7.5 6.4 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLTH PF10607.9 KFH41828.1 - 7.1e-31 107.1 0.0 1.3e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFH41828.1 - 1.5e-05 24.9 0.1 2.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH41828.1 - 0.023 15.0 0.3 0.041 14.2 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.12 KFH41828.1 - 0.025 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger YfdX PF10938.8 KFH41828.1 - 0.046 13.6 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 YfdX protein zf-C3HC4_3 PF13920.6 KFH41828.1 - 0.099 12.5 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH41828.1 - 0.12 12.3 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KFH41828.1 - 0.13 12.2 0.5 0.24 11.3 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KFH41831.1 - 5.7e-16 58.4 0.0 9.6e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KFH41831.1 - 2.8e-08 33.3 2.8 0.00099 18.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFH41831.1 - 2.8e-06 27.9 5.4 0.005 17.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH41831.1 - 5.6e-06 26.1 4.8 0.017 15.2 0.4 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH41831.1 - 0.0017 18.0 0.2 0.9 9.3 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 KFH41831.1 - 0.052 14.4 7.4 27 5.9 0.0 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat MC1 PF05854.11 KFH41831.1 - 0.068 13.5 0.2 0.16 12.3 0.1 1.7 2 0 0 2 2 1 0 Non-histone chromosomal protein MC1 TPR_12 PF13424.6 KFH41831.1 - 0.091 13.1 10.1 0.97 9.8 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFH41831.1 - 0.11 12.8 4.1 16 6.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFH41831.1 - 0.15 12.5 1.7 5.3 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH41831.1 - 0.37 10.9 3.8 1.2 9.3 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFH41831.1 - 1.3 8.9 8.7 13 5.8 0.0 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 KFH41832.1 - 2.1e-49 168.5 0.0 1.3e-27 96.7 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 DIE2_ALG10 PF04922.12 KFH41834.1 - 3.9e-126 421.5 0.8 2.4e-125 418.9 0.8 1.9 1 1 0 1 1 1 1 DIE2/ALG10 family HSP9_HSP12 PF04119.12 KFH41834.1 - 1.4 9.4 4.0 0.36 11.2 0.5 1.7 2 0 0 2 2 2 0 Heat shock protein 9/12 Amidase PF01425.21 KFH41835.1 - 4.9e-55 187.3 0.0 1e-54 186.3 0.0 1.4 1 1 0 1 1 1 1 Amidase DUF5577 PF17740.1 KFH41836.1 - 0.072 12.8 2.0 0.088 12.5 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5577) Cutinase PF01083.22 KFH41837.1 - 4.7e-40 137.4 2.3 8e-40 136.7 2.3 1.4 1 1 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFH41837.1 - 8.3e-05 22.2 0.1 0.0004 20.0 0.1 1.8 1 1 0 2 2 2 1 PE-PPE domain LIP PF03583.14 KFH41837.1 - 0.0048 16.2 0.4 0.0079 15.5 0.4 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 KFH41837.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sugarporin_N PF11471.8 KFH41837.1 - 0.71 9.9 2.8 0.74 9.8 1.2 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension UPF0183 PF03676.14 KFH41838.1 - 2.7e-53 181.7 0.0 3.2e-32 112.3 0.0 3.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) DUF5082 PF16888.5 KFH41839.1 - 0.0096 16.2 0.4 0.021 15.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) PG_binding_1 PF01471.18 KFH41839.1 - 0.017 15.3 0.0 5.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Putative peptidoglycan binding domain ATG16 PF08614.11 KFH41839.1 - 0.02 15.1 1.8 0.044 14.0 1.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1640 PF07798.11 KFH41839.1 - 0.024 14.7 0.5 0.042 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_13 PF13166.6 KFH41839.1 - 0.062 11.9 0.2 0.09 11.4 0.2 1.1 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 KFH41839.1 - 0.69 10.3 2.2 1.2 9.5 0.7 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain SlyX PF04102.12 KFH41839.1 - 0.71 10.5 3.1 0.45 11.2 0.4 2.0 2 0 0 2 2 2 0 SlyX Med4 PF10018.9 KFH41840.1 - 5.3e-37 127.4 20.3 3e-36 125.0 20.3 2.2 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TFIIA PF03153.13 KFH41840.1 - 0.11 12.5 13.4 0.14 12.2 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3027 PF11228.8 KFH41840.1 - 0.27 11.3 4.2 0.12 12.3 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) Pinin_SDK_memA PF04696.13 KFH41840.1 - 0.32 11.0 25.5 0.055 13.5 20.3 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 KFH41840.1 - 0.75 9.1 10.1 4.4 6.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDRGK PF09756.9 KFH41840.1 - 1.9 8.1 22.5 3.7 7.1 22.5 1.4 1 0 0 1 1 1 0 DDRGK domain Nucleo_P87 PF07267.11 KFH41840.1 - 5.8 5.6 8.9 7.7 5.2 8.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ASF1_hist_chap PF04729.13 KFH41841.1 - 9.7e-73 243.2 0.0 1.3e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DMSP_lyase PF16867.5 KFH41841.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Nop14 PF04147.12 KFH41841.1 - 1.9 6.6 21.8 2.3 6.3 21.8 1.1 1 0 0 1 1 1 0 Nop14-like family Piwi PF02171.17 KFH41842.1 - 2.3e-80 270.1 0.0 3.2e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFH41842.1 - 8.4e-16 58.8 0.0 2.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFH41842.1 - 4e-12 45.6 0.0 1.3e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFH41842.1 - 9.2e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KFH41842.1 - 2.7e-08 34.0 0.0 9.8e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KFH41842.1 - 0.0015 18.7 0.2 0.0053 17.0 0.2 1.9 1 0 0 1 1 1 1 Mid domain of argonaute bPH_4 PF06713.11 KFH41842.1 - 0.13 12.3 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial PH domain PAP2_3 PF14378.6 KFH41843.1 - 4.2e-24 85.3 11.7 4.2e-24 85.3 11.7 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KFH41843.1 - 8.2e-11 41.8 4.7 8.2e-11 41.8 4.7 2.7 2 1 0 2 2 2 1 PAP2 superfamily CPBP PF02517.16 KFH41843.1 - 0.02 15.3 1.0 0.02 15.3 1.0 3.0 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease SHMT PF00464.19 KFH41845.1 - 8.2e-205 680.0 0.0 1e-204 679.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KFH41845.1 - 9.3e-05 21.8 0.0 0.0003 20.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFH41845.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFH41845.1 - 0.097 11.2 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFH41845.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase RRM_1 PF00076.22 KFH41846.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH41846.1 - 6.6e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.21 KFH41847.1 - 3.8e-22 78.3 44.3 9.4e-12 45.0 5.6 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFH41847.1 - 3.2e-05 23.7 4.8 3.2e-05 23.7 4.8 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH41847.1 - 0.00023 21.4 6.3 0.00023 21.4 6.3 4.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFH41847.1 - 0.0039 17.1 6.8 0.0039 17.1 6.8 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH41847.1 - 0.005 16.6 5.2 0.005 16.6 5.2 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH41847.1 - 0.0084 16.1 4.0 0.0084 16.1 4.0 3.8 3 1 0 3 3 3 1 RING-type zinc-finger Trp_syntA PF00290.20 KFH41847.1 - 0.051 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain zf-C3HC4_4 PF15227.6 KFH41847.1 - 0.12 12.6 0.3 0.12 12.6 0.3 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING UN_NPL4 PF11543.8 KFH41847.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Y_phosphatase PF00102.27 KFH41848.1 - 2.5e-49 168.0 0.0 4.8e-49 167.0 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFH41848.1 - 2.7e-05 24.3 0.0 6.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFH41848.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Sporozoite_P67 PF05642.11 KFH41848.1 - 0.004 15.3 2.5 0.0051 15.0 2.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DSPc PF00782.20 KFH41848.1 - 0.032 14.1 0.1 0.078 12.8 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Mucin PF01456.17 KFH41848.1 - 0.065 13.2 16.3 0.11 12.5 16.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 KFH41848.1 - 0.45 10.5 9.3 0.34 10.9 7.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 KFH41848.1 - 1 7.3 3.6 1.3 6.9 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med13_C PF06333.12 KFH41848.1 - 1 8.6 7.8 1.6 7.9 7.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain LAT PF15234.6 KFH41848.1 - 1.1 9.0 7.4 1.8 8.2 6.1 1.9 1 1 1 2 2 2 0 Linker for activation of T-cells SSP160 PF06933.11 KFH41848.1 - 4.3 5.4 14.6 5.9 5.0 14.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RasGAP PF00616.19 KFH41849.1 - 1.5e-53 181.6 0.0 6.3e-53 179.6 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFH41849.1 - 1.8e-29 102.6 4.1 1.8e-29 102.6 4.1 2.7 3 0 0 3 3 3 1 RasGAP C-terminus COG5 PF10392.9 KFH41849.1 - 0.034 14.3 1.3 0.3 11.3 0.2 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Prominin PF05478.11 KFH41849.1 - 0.74 7.7 6.0 0.28 9.1 0.0 2.4 3 0 0 3 3 3 0 Prominin LHH PF14411.6 KFH41849.1 - 0.83 9.9 3.4 23 5.2 2.3 3.0 2 1 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH APG6_N PF17675.1 KFH41849.1 - 4.6 7.8 9.5 4.9 7.7 3.4 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KFH41849.1 - 5.1 7.8 7.2 6.1 7.5 0.8 2.8 2 0 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KFH41849.1 - 5.4 7.0 11.2 0.4 10.7 1.5 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VanZ PF04892.12 KFH41850.1 - 4.9e-08 33.7 2.8 6.8e-08 33.2 2.8 1.2 1 0 0 1 1 1 1 VanZ like family RseC_MucC PF04246.12 KFH41850.1 - 0.18 11.7 0.5 9.3 6.2 0.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phage_holin_2_4 PF16082.5 KFH41850.1 - 0.2 11.4 0.2 0.43 10.3 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MAM33 PF02330.16 KFH41851.1 - 5.1e-71 239.0 2.3 2.8e-70 236.5 2.3 1.9 1 1 0 1 1 1 1 Mitochondrial glycoprotein CLP1_P PF16575.5 KFH41852.1 - 3.5e-30 105.2 0.0 9.5e-30 103.8 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Hormone_2 PF00123.20 KFH41852.1 - 0.067 13.1 0.7 8 6.5 0.4 2.4 2 0 0 2 2 2 0 Peptide hormone RNA_polI_A34 PF08208.11 KFH41854.1 - 1.7e-41 142.6 14.6 1.7e-41 142.6 14.6 7.1 2 2 3 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 Suf PF05843.14 KFH41855.1 - 1.3e-85 288.0 8.0 6.1e-84 282.5 0.0 4.6 4 2 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFH41855.1 - 2.4e-05 24.8 0.5 0.27 12.1 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat HrpJ PF07201.11 KFH41855.1 - 0.016 15.6 0.0 1.9 8.8 0.0 3.0 2 0 0 2 2 2 0 HrpJ-like domain HAT PF02184.16 KFH41855.1 - 0.069 13.1 0.3 0.61 10.1 0.1 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat FAM176 PF14851.6 KFH41855.1 - 2.4 7.8 3.9 5.6 6.6 0.4 2.4 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 KFH41856.1 - 0.071 13.4 5.2 0.12 12.7 5.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 KFH41856.1 - 2 6.4 4.5 2.2 6.3 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi ERF PF04404.12 KFH41856.1 - 6.4 6.6 8.0 41 4.0 0.1 2.2 1 1 1 2 2 2 0 ERF superfamily Pkinase PF00069.25 KFH41857.1 - 1.2e-71 241.2 0.0 1.4e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41857.1 - 5.6e-29 101.2 0.0 7.7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH41857.1 - 5.1e-07 29.3 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFH41857.1 - 7.8e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFH41857.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH41857.1 - 0.00085 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.18 KFH41858.1 - 7.4e-14 51.8 0.1 1.4e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.13 KFH41858.1 - 0.0077 16.3 0.2 0.79 9.8 0.2 2.5 2 0 0 2 2 2 1 DivIVA protein DivIC PF04977.15 KFH41858.1 - 7.3 6.4 6.6 2.6 7.9 0.4 2.9 3 0 0 3 3 3 0 Septum formation initiator Ferric_reduct PF01794.19 KFH41859.1 - 8.9e-16 58.1 9.2 8.9e-16 58.1 9.2 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH41859.1 - 1.5e-10 41.4 0.0 1.3e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH41859.1 - 3.1e-08 33.7 0.0 6.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFH41859.1 - 3.9e-05 24.3 0.1 0.18 12.5 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RF-1 PF00472.20 KFH41860.1 - 1.2e-15 57.5 2.9 1.8e-15 56.9 2.9 1.2 1 0 0 1 1 1 1 RF-1 domain UPF0300 PF08594.10 KFH41860.1 - 0.084 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) TMF_TATA_bd PF12325.8 KFH41860.1 - 0.16 12.2 3.8 0.26 11.5 3.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding XPG_I PF00867.18 KFH41861.1 - 3.7e-23 81.7 0.0 9.6e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFH41861.1 - 6.6e-06 26.5 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFH41861.1 - 0.0011 18.6 0.3 0.0035 16.8 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 KFH41861.1 - 0.0037 17.8 0.0 0.013 16.1 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_8 PF13181.6 KFH41861.1 - 0.042 14.1 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_5 PF14520.6 KFH41861.1 - 0.1 13.2 0.2 2.5 8.8 0.0 2.9 3 1 0 3 3 3 0 Helix-hairpin-helix domain TPR_2 PF07719.17 KFH41861.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Redoxin PF08534.10 KFH41863.1 - 1.3e-22 80.1 0.0 1.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Bromodomain PF00439.25 KFH41864.1 - 2.2e-18 66.1 0.3 6e-18 64.7 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KFH41864.1 - 1.9e-12 47.0 0.1 4.5e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated PSII_Pbs27 PF13326.6 KFH41864.1 - 0.021 15.1 0.3 0.083 13.2 0.3 2.1 1 0 0 1 1 1 0 Photosystem II Pbs27 ING PF12998.7 KFH41864.1 - 0.23 12.0 2.3 7.4 7.2 1.1 2.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4611 PF15387.6 KFH41864.1 - 0.76 10.0 7.8 13 6.1 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KFH41864.1 - 5.2 7.5 12.2 8.2 6.9 2.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Oxysterol_BP PF01237.18 KFH41865.1 - 1.9e-49 168.5 0.0 4.9e-47 160.5 0.0 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein Tma16 PF11176.8 KFH41866.1 - 1.5e-37 128.7 6.5 1.2e-35 122.5 6.5 2.6 1 1 0 1 1 1 1 Translation machinery-associated protein 16 Lgl_C PF08596.10 KFH41868.1 - 1e-120 403.1 0.0 2.1e-120 402.0 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KFH41868.1 - 1e-05 26.1 2.7 0.0068 17.2 0.4 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41868.1 - 0.00045 20.4 0.0 0.091 13.1 0.0 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFH41868.1 - 0.0031 17.2 0.1 2.5 7.6 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain TAA-Trp-ring PF15401.6 KFH41868.1 - 0.026 15.0 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Filament_head PF04732.14 KFH41869.1 - 2.2 9.2 10.7 0.44 11.5 6.0 1.9 1 1 1 2 2 2 0 Intermediate filament head (DNA binding) region APH PF01636.23 KFH41870.1 - 1.7e-21 77.3 0.0 2.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFH41870.1 - 0.0023 17.5 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 KFH41870.1 - 0.0042 16.7 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KFH41870.1 - 0.033 13.4 0.0 0.73 9.0 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase MaoC_dehydrat_N PF13452.6 KFH41871.1 - 0.0033 17.6 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase OmdA PF13376.6 KFH41873.1 - 5.8e-16 58.2 0.2 1.2e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated GST_N_2 PF13409.6 KFH41874.1 - 2.7e-21 75.6 0.0 5.3e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH41874.1 - 1.6e-13 50.5 0.0 3.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFH41874.1 - 0.00024 21.4 0.0 0.0017 18.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFH41874.1 - 0.00031 20.9 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH41874.1 - 0.00099 19.3 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFH41874.1 - 0.0029 17.4 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VIT1 PF01988.19 KFH41876.1 - 0.0086 16.0 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 VIT family SAM_adeno_trans PF01887.16 KFH41877.1 - 0.038 13.4 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Aspzincin_M35 PF14521.6 KFH41877.1 - 0.075 13.6 0.1 0.16 12.5 0.0 1.5 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase ECH_1 PF00378.20 KFH41878.1 - 2.1e-41 141.9 0.0 3.7e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH41878.1 - 4.7e-19 69.1 0.1 1.5e-18 67.4 0.1 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFH41878.1 - 0.049 13.6 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 Se-cys_synth_N PF12390.8 KFH41878.1 - 0.33 11.2 2.2 11 6.4 0.2 2.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Ank_2 PF12796.7 KFH41879.1 - 1e-20 74.1 0.0 1.7e-11 44.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFH41879.1 - 4.9e-20 71.0 0.0 1.1e-06 28.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFH41879.1 - 1.3e-19 70.0 1.4 3.7e-11 43.0 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH41879.1 - 3.4e-17 60.8 0.0 4.6e-05 23.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFH41879.1 - 6.3e-16 58.5 1.5 8.3e-09 35.8 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SesA PF17107.5 KFH41879.1 - 0.02 15.1 0.2 0.047 13.9 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2384 PF09722.10 KFH41879.1 - 0.024 14.7 0.8 0.38 10.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) WXG100 PF06013.12 KFH41879.1 - 0.04 14.2 0.3 0.04 14.2 0.3 2.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG TMP_2 PF06791.13 KFH41879.1 - 0.077 12.7 0.4 0.16 11.6 0.4 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein Fib_alpha PF08702.10 KFH41879.1 - 0.097 12.9 0.7 1.1 9.5 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Hydantoinase_B PF02538.14 KFH41881.1 - 1.4e-206 687.0 0.4 1.8e-206 686.6 0.4 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFH41881.1 - 1.7e-89 299.9 0.0 3.6e-89 298.9 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFH41881.1 - 2.6e-59 199.9 0.2 8.4e-58 195.0 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MHC_I_C PF06623.11 KFH41881.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 MHC_I C-terminus Glyco_hydro_25 PF01183.20 KFH41882.1 - 1.7e-44 152.1 1.5 2e-44 151.9 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 HAMP PF00672.25 KFH41883.1 - 3.2e-38 129.9 17.4 2.5e-08 34.2 0.5 8.5 7 2 1 8 8 8 5 HAMP domain HATPase_c PF02518.26 KFH41883.1 - 7.4e-29 100.5 3.1 1.3e-28 99.7 0.3 2.9 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH41883.1 - 6.2e-26 90.8 0.9 2.3e-25 88.9 0.9 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFH41883.1 - 5.3e-18 64.8 2.3 2.5e-17 62.6 0.4 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 KFH41883.1 - 5.8e-05 23.3 0.1 19 5.5 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) Syntaxin_2 PF14523.6 KFH41883.1 - 0.0037 17.6 15.9 1.8 8.9 0.1 6.7 3 3 2 6 6 6 1 Syntaxin-like protein DUF3829 PF12889.7 KFH41883.1 - 0.012 15.1 7.6 3.2 7.2 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF3829) IF2_assoc PF08364.11 KFH41883.1 - 0.028 14.7 1.6 8.3 6.8 0.5 2.7 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region PMC2NT PF08066.12 KFH41883.1 - 0.032 14.9 6.4 2.3 9.0 2.4 4.9 3 1 0 3 3 3 0 PMC2NT (NUC016) domain DUF883 PF05957.13 KFH41883.1 - 0.033 14.8 10.9 3.3 8.4 0.2 5.8 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF883) CENP-F_leu_zip PF10473.9 KFH41883.1 - 0.063 13.3 16.4 20 5.2 0.0 6.4 6 2 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 KFH41883.1 - 0.068 12.8 16.9 3.6 7.1 0.5 4.9 2 2 3 5 5 5 0 Domain of unknown function (DUF4795) DUF948 PF06103.11 KFH41883.1 - 0.071 13.4 43.6 2 8.7 3.4 9.0 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) ImcF-related_N PF14331.6 KFH41883.1 - 0.085 12.2 3.4 9.3 5.5 0.1 3.7 3 1 2 5 5 5 0 ImcF-related N-terminal domain Fib_alpha PF08702.10 KFH41883.1 - 0.21 11.8 35.0 0.63 10.2 0.1 6.3 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family MCM_N PF14551.6 KFH41883.1 - 0.45 11.1 2.4 13 6.4 0.0 4.0 4 1 0 4 4 4 0 MCM N-terminal domain GLE1 PF07817.13 KFH41883.1 - 0.51 9.5 10.7 17 4.5 0.1 5.0 3 1 2 5 5 5 0 GLE1-like protein WXG100 PF06013.12 KFH41883.1 - 3.5 7.9 20.1 13 6.1 0.2 6.9 5 2 2 7 7 6 0 Proteins of 100 residues with WXG DASH_Duo1 PF08651.10 KFH41883.1 - 3.7 7.4 10.9 10 6.0 0.1 5.7 6 0 0 6 6 6 0 DASH complex subunit Duo1 TMV_coat PF00721.21 KFH41883.1 - 7 6.5 7.3 11 5.9 0.6 3.5 2 1 1 3 3 3 0 Virus coat protein (TMV like) MFS_1 PF07690.16 KFH41884.1 - 2e-38 132.2 22.0 6.8e-38 130.5 22.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 KFH41885.1 - 3.9e-20 72.3 0.0 4.8e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41885.1 - 6e-09 35.6 0.0 7.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Bac_rhamnosid6H PF17389.2 KFH41889.1 - 1.4e-15 57.5 0.4 1.2e-13 51.1 0.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFH41889.1 - 6.8e-10 38.6 0.1 1.3e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KFH41889.1 - 0.00061 18.8 0.0 0.013 14.4 0.0 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF608 PF04685.13 KFH41889.1 - 0.00082 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Bac_rhamnosid PF05592.11 KFH41889.1 - 0.035 14.1 0.0 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain SsgA PF04686.12 KFH41889.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA HD PF01966.22 KFH41891.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 HD domain MFS_1 PF07690.16 KFH41892.1 - 1.1e-37 129.9 61.7 2.3e-28 99.2 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KFH41893.1 - 2.2e-24 85.7 0.5 4.1e-24 84.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH41893.1 - 0.045 13.8 0.7 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Berberine and berberine like tRNA-synt_2c PF01411.19 KFH41894.1 - 8.8e-10 37.7 0.0 1.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFH41894.1 - 6.6e-05 22.9 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GFP PF01353.22 KFH41894.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein Glyco_hydro_61 PF03443.14 KFH41895.1 - 8.1e-67 225.1 0.0 9.6e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KFH41895.1 - 0.013 15.8 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase HAD PF12710.7 KFH41896.1 - 0.081 13.3 0.0 1.1 9.6 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KFH41897.1 - 1.4e-21 76.7 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH41897.1 - 6e-06 26.3 9.8 9.9e-06 25.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2273 PF10031.9 KFH41898.1 - 2.3 8.3 6.8 0.66 10.0 1.3 2.4 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Tim17 PF02466.19 KFH41899.1 - 8.9e-13 48.6 0.1 2.1e-12 47.4 0.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family BPD_transp_2 PF02653.16 KFH41899.1 - 0.029 13.5 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component NADH-u_ox-rdase PF10785.9 KFH41899.1 - 0.15 12.8 0.5 13 6.6 0.1 3.2 2 2 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit zf-RING_4 PF14570.6 KFH41901.1 - 0.55 10.1 3.6 1.7 8.5 3.6 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_clus PF00172.18 KFH41901.1 - 0.57 10.4 5.7 1.2 9.3 5.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KFH41901.1 - 0.71 10.4 4.8 1.8 9.1 4.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region GMP_synt_C PF00958.22 KFH41902.1 - 2.7e-32 110.7 0.1 4.7e-32 109.9 0.1 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KFH41902.1 - 3.3e-15 56.3 0.0 6.7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KFH41902.1 - 1.1e-07 31.3 0.1 3.5e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 KFH41902.1 - 0.0036 16.2 0.1 0.0068 15.2 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KFH41902.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KFH41902.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase QueC PF06508.13 KFH41902.1 - 0.022 14.2 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 KFH41902.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KFH41902.1 - 0.058 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Peptidase_C26 PF07722.13 KFH41902.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 NDUFB10 PF10249.9 KFH41903.1 - 0.014 15.9 0.0 0.02 15.4 0.0 1.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Homeodomain PF00046.29 KFH41904.1 - 2.7e-15 55.9 2.9 6e-15 54.8 2.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFH41904.1 - 0.0095 15.8 0.9 0.0095 15.8 0.9 2.3 2 0 0 2 2 2 1 Homeobox KN domain Annexin PF00191.20 KFH41905.1 - 6.6e-72 237.5 1.3 5.7e-19 67.9 0.3 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 KFH41905.1 - 0.0013 18.5 0.1 3 7.7 0.1 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3574) Minor_tail_Z PF06763.11 KFH41905.1 - 0.12 12.1 0.0 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) F-box-like PF12937.7 KFH41907.1 - 0.00043 20.1 0.1 0.0017 18.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFH41907.1 - 0.15 12.5 9.4 0.55 10.7 0.1 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH41907.1 - 1.2 8.9 7.0 1.8 8.4 0.6 2.9 3 0 0 3 3 3 0 Leucine rich repeat WH2 PF02205.20 KFH41908.1 - 4.7e-09 35.8 0.6 4.7e-09 35.8 0.6 2.0 2 0 0 2 2 2 1 WH2 motif Questin_oxidase PF14027.6 KFH41909.1 - 4.3e-87 292.8 0.5 5.3e-87 292.5 0.5 1.1 1 0 0 1 1 1 1 Questin oxidase-like AICARFT_IMPCHas PF01808.18 KFH41911.1 - 2.9e-91 306.0 0.0 3.9e-91 305.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFH41911.1 - 5.5e-24 84.2 0.0 9.9e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain PCI PF01399.27 KFH41913.1 - 2.5e-14 53.6 0.0 3.2e-13 50.1 0.0 2.7 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 KFH41913.1 - 2.6e-05 24.0 0.6 6.5e-05 22.7 0.6 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 DNA_pol_B_palm PF14792.6 KFH41914.1 - 1.2e-36 125.4 0.0 2.9e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KFH41914.1 - 2.5e-24 85.2 0.2 2.2e-23 82.2 0.3 2.6 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFH41914.1 - 2.3e-19 69.0 0.6 5.2e-19 67.8 0.6 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFH41914.1 - 2e-17 63.3 0.6 4.8e-17 62.1 0.4 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFH41914.1 - 0.01 16.1 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain BRCT_2 PF16589.5 KFH41914.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-C2H2_4 PF13894.6 KFH41915.1 - 0.52 11.3 10.6 3.3 8.8 1.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH41915.1 - 1.4 9.5 12.1 0.93 10.1 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type APH PF01636.23 KFH41916.1 - 2e-14 54.1 2.0 6.9e-14 52.3 2.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nore1-SARAH PF16517.5 KFH41916.1 - 0.093 12.7 0.3 0.27 11.2 0.3 1.8 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RRM_1 PF00076.22 KFH41917.1 - 1.5e-25 88.7 0.2 2.2e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH41917.1 - 0.0023 18.0 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Asn_synthase PF00733.21 KFH41918.1 - 2.3e-18 67.0 3.9 9.2e-10 38.7 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFH41918.1 - 1.4e-09 37.9 0.0 5e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFH41918.1 - 6.5e-06 26.4 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SH3_9 PF14604.6 KFH41918.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain BTB PF00651.31 KFH41919.1 - 0.00044 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF3439 PF11921.8 KFH41919.1 - 0.51 10.3 9.6 0.99 9.4 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 KFH41919.1 - 3.1 5.6 4.1 4.3 5.2 4.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PMSI1 PF15322.6 KFH41919.1 - 6 6.2 12.0 1.3 8.4 0.6 2.2 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative Ppx-GppA PF02541.16 KFH41920.1 - 6e-27 94.8 0.0 2e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family TIR_2 PF13676.6 KFH41921.1 - 0.052 14.1 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain Cas3_C PF18395.1 KFH41921.1 - 0.26 11.8 1.6 0.46 11.0 0.5 1.9 1 1 1 2 2 2 0 Cas3 C-terminal domain GATase PF00117.28 KFH41922.1 - 3.7e-10 39.9 0.0 4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFH41922.1 - 0.14 11.9 0.3 0.22 11.2 0.1 1.4 2 0 0 2 2 2 0 Peptidase C26 Ribosomal_L37 PF08561.10 KFH41925.1 - 1.4e-40 138.6 1.3 1.7e-40 138.2 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 HECT_2 PF09814.9 KFH41926.1 - 1.7e-79 267.4 2.5 1.4e-65 221.6 0.2 2.3 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.23 KFH41926.1 - 1.5e-39 135.7 0.0 9.9e-37 126.5 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41926.1 - 1.2e-06 28.9 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41926.1 - 0.0009 19.3 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DNA_RNApol_7kD PF03604.13 KFH41926.1 - 0.19 11.4 1.6 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TraW_N PF12477.8 KFH41927.1 - 0.55 10.3 4.7 0.23 11.4 1.8 1.9 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Rad17 PF03215.15 KFH41928.1 - 9.1e-28 97.4 0.0 2.1e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFH41928.1 - 0.0014 19.0 0.1 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFH41928.1 - 0.036 14.5 0.0 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH41928.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KFH41928.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Seryl_tRNA_N PF02403.22 KFH41929.1 - 0.005 17.0 3.0 0.0096 16.1 3.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RAP1 PF07218.11 KFH41929.1 - 0.036 12.4 1.0 0.051 11.9 1.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lipase_GDSL_2 PF13472.6 KFH41931.1 - 1.6e-20 74.3 1.4 4e-20 73.0 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH41931.1 - 1.8e-06 28.1 0.0 9.1e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cpn60_TCP1 PF00118.24 KFH41932.1 - 1e-143 479.6 10.6 1.2e-143 479.4 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KFH41932.1 - 0.021 15.0 0.2 0.052 13.8 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KFH41932.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat RabGAP-TBC PF00566.18 KFH41933.1 - 5.1e-30 104.7 0.0 7.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KFH41933.1 - 1.2e-08 33.7 3.5 1.3e-08 33.6 0.8 2.0 1 1 1 2 2 2 1 SBE2, cell-wall formation SNF2_N PF00176.23 KFH41934.1 - 1e-65 221.8 0.2 1.6e-65 221.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH41934.1 - 1.4e-17 64.0 0.0 8.2e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH41934.1 - 2.9e-09 37.2 0.0 5.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KFH41934.1 - 0.014 15.7 12.0 0.084 13.2 11.9 2.5 1 1 0 1 1 1 0 HSA HDA2-3 PF11496.8 KFH41934.1 - 0.041 13.0 0.0 3.6 6.7 0.0 2.8 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 FA_desaturase PF00487.24 KFH41935.1 - 9.2e-24 84.6 18.3 2e-23 83.6 18.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFH41935.1 - 2.3e-09 37.5 0.0 2.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Zn_clus PF00172.18 KFH41936.1 - 4.8e-08 33.0 11.1 1.1e-07 31.8 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH41936.1 - 2.5e-05 23.3 2.0 2.5e-05 23.3 2.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain RyR PF02026.16 KFH41936.1 - 0.063 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 RyR domain Fungal_trans PF04082.18 KFH41937.1 - 4.7e-22 78.3 0.0 9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 KFH41937.1 - 1.2e-19 70.6 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Amidase Ilm1 PF10311.9 KFH41938.1 - 6.9e-64 214.5 0.1 7.9e-64 214.3 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ribonuc_2-5A PF06479.12 KFH41939.1 - 1.3e-44 151.5 0.0 2.7e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KFH41939.1 - 1.7e-41 142.3 0.0 1e-29 103.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41939.1 - 2.8e-21 76.0 0.0 4.6e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 KFH41939.1 - 3.1e-07 30.0 2.5 0.0046 16.8 0.0 4.0 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KFH41939.1 - 1.5e-05 24.7 0.2 0.00027 20.6 0.2 2.4 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 KFH41939.1 - 0.00064 19.1 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFH41939.1 - 0.003 16.4 0.0 0.003 16.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFH41939.1 - 0.0034 17.4 0.3 0.057 13.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 KFH41940.1 - 4.4e-06 26.5 9.0 4.4e-06 26.5 9.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) E_raikovi_mat PF06360.11 KFH41940.1 - 4.5 7.8 5.9 0.96 9.9 0.2 2.6 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone zf-C3HC4_2 PF13923.6 KFH41940.1 - 5.7 6.9 21.8 0.04 13.8 10.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GH131_N PF18271.1 KFH41941.1 - 2e-59 201.4 0.0 2.3e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF604 PF04646.12 KFH41943.1 - 2e-14 53.6 0.0 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 KFH41943.1 - 2.1e-07 30.6 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like CHCH PF06747.13 KFH41945.1 - 0.002 18.2 6.3 0.0035 17.4 6.3 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KFH41945.1 - 0.0036 17.5 2.0 0.0047 17.1 2.0 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COX17 PF05051.13 KFH41945.1 - 0.049 14.0 1.3 0.071 13.5 1.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pectate_lyase_3 PF12708.7 KFH41946.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 2 0 0 2 2 2 0 Pectate lyase superfamily protein eIF2A PF08662.11 KFH41947.1 - 2.2e-39 135.3 0.7 8.1e-37 127.0 0.1 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFH41947.1 - 0.0079 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3091 PF11291.8 KFH41949.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Ribonuclease PF00545.20 KFH41950.1 - 4.3e-06 27.4 0.0 7.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 ribonuclease NDUF_B8 PF05821.11 KFH41951.1 - 4.8e-09 36.3 0.2 5.5e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) 2OG-FeII_Oxy_3 PF13640.6 KFH41952.1 - 1.4e-09 38.7 0.0 2.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SWIB PF02201.18 KFH41954.1 - 2e-28 98.1 0.1 4e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KFH41954.1 - 5.7e-16 58.2 0.5 1.3e-15 57.0 0.5 1.6 1 0 0 1 1 1 1 DEK C terminal domain FliT PF05400.13 KFH41954.1 - 0.029 15.2 2.0 1.4 9.8 0.2 2.5 2 0 0 2 2 2 0 Flagellar protein FliT GST_N_3 PF13417.6 KFH41955.1 - 3.9e-16 59.2 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFH41955.1 - 2e-14 53.7 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFH41955.1 - 1.7e-13 50.6 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFH41955.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFH41955.1 - 3.7e-09 36.7 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH41955.1 - 2.2e-06 27.6 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFH41955.1 - 0.035 14.8 0.0 0.089 13.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Pkinase PF00069.25 KFH41956.1 - 2.3e-65 220.6 0.0 3.3e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH41956.1 - 6.3e-40 137.1 0.0 9.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH41956.1 - 4.9e-09 35.9 0.0 2.8e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFH41956.1 - 8.4e-05 21.7 0.0 8.4e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFH41956.1 - 0.00067 19.7 3.2 0.024 14.5 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH41956.1 - 0.026 13.9 0.0 0.077 12.3 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFH41956.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 CcdA PF07362.12 KFH41956.1 - 0.63 10.5 2.9 8.2 6.9 2.9 2.5 1 1 0 1 1 1 0 Post-segregation antitoxin CcdA Choline_kinase PF01633.20 KFH41956.1 - 2.1 7.9 5.0 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF3445 PF11927.8 KFH41957.1 - 3.4e-61 206.8 0.0 5.5e-48 163.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) CcmD PF04995.14 KFH41957.1 - 0.46 10.6 2.9 0.85 9.7 2.9 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NatB_MDM20 PF09797.9 KFH41958.1 - 1e-51 176.1 0.0 1.5e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_12 PF13424.6 KFH41959.1 - 6e-13 48.9 0.6 6.4e-08 32.8 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFH41959.1 - 4.7e-09 35.8 0.1 0.00011 22.0 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH41959.1 - 6.5e-08 32.1 1.0 8.1e-05 22.3 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH41959.1 - 0.00033 20.6 4.4 0.13 12.4 0.2 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFH41959.1 - 0.00035 21.0 0.0 0.0013 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFH41959.1 - 0.00098 19.4 0.0 0.0067 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KFH41959.1 - 0.001 18.9 0.4 0.033 14.2 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NB-ARC PF00931.22 KFH41959.1 - 0.0014 17.9 0.1 0.12 11.5 0.1 2.5 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KFH41959.1 - 0.0025 18.5 0.5 7.3 7.7 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH41959.1 - 0.017 15.3 7.1 0.53 10.6 0.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat ATPase PF06745.13 KFH41959.1 - 0.034 13.5 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC TPR_MalT PF17874.1 KFH41959.1 - 0.038 13.4 0.1 5.1 6.4 0.1 3.0 1 1 0 2 2 2 0 MalT-like TPR region TPR_3 PF07720.12 KFH41959.1 - 0.039 13.9 2.6 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat U6-snRNA_bdg PF10596.9 KFH41959.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 RPN7 PF10602.9 KFH41959.1 - 1.5 8.5 4.1 21 4.7 0.0 3.3 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Prenyltrans PF00432.21 KFH41960.1 - 2.3e-37 126.4 10.7 6.4e-08 32.2 0.0 6.9 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFH41960.1 - 3.2e-05 23.2 0.0 0.00025 20.2 0.0 2.3 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain Arylesterase PF01731.20 KFH41962.1 - 0.036 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Nup160 PF11715.8 KFH41962.1 - 0.09 11.4 0.1 0.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Collagen PF01391.18 KFH41963.1 - 7.3e-05 22.5 7.6 0.00012 21.8 7.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CHAT PF12770.7 KFH41964.1 - 1.2e-05 24.9 0.2 1.8e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 CHAT domain Mucin PF01456.17 KFH41964.1 - 0.082 12.9 3.3 0.17 11.8 3.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.18 KFH41965.1 - 0.0011 19.0 12.0 0.0011 19.0 12.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BTRF1 PF04682.12 KFH41965.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region FBPase PF00316.20 KFH41966.1 - 3.1e-24 85.5 0.0 4.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain polyprenyl_synt PF00348.17 KFH41967.1 - 1.1e-60 204.8 0.0 1.4e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 KFH41967.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Translin family Haem_degrading PF03928.14 KFH41968.1 - 4.6e-33 113.8 0.0 5.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Zn_clus PF00172.18 KFH41970.1 - 8.2e-08 32.3 23.2 0.00013 22.0 3.1 3.1 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol3_gamma3 PF12169.8 KFH41970.1 - 0.2 11.6 0.6 0.44 10.4 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III GST_N PF02798.20 KFH41971.1 - 1.9e-16 60.2 0.0 3.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFH41971.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFH41971.1 - 4e-11 43.0 0.0 7.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFH41971.1 - 6.5e-09 35.9 0.0 1.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH41971.1 - 7e-08 32.6 0.2 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH41971.1 - 9e-07 28.8 0.1 7.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Med11 PF10280.9 KFH41973.1 - 1.6e-46 158.1 0.0 1.9e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex protein Vps5 PF09325.10 KFH41974.1 - 5.3e-87 291.3 2.9 8.2e-87 290.6 2.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KFH41974.1 - 1.9e-24 85.8 0.3 3.9e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KFH41974.1 - 0.002 17.9 5.2 0.12 12.1 1.3 2.5 1 1 1 2 2 2 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 KFH41974.1 - 0.0025 17.3 0.9 0.011 15.2 0.9 2.0 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_2 PF10455.9 KFH41974.1 - 0.015 14.5 1.3 0.024 13.8 1.3 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3450 PF11932.8 KFH41974.1 - 0.043 13.1 4.7 0.082 12.2 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF713 PF05218.14 KFH41974.1 - 0.14 11.8 4.9 0.1 12.3 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF713) BAR PF03114.18 KFH41974.1 - 0.54 9.9 8.4 1 8.9 8.4 1.5 1 1 0 1 1 1 0 BAR domain Ytp1 PF10355.9 KFH41975.1 - 7.7e-67 225.4 22.2 7.7e-67 225.4 22.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFH41975.1 - 3e-23 81.6 3.9 2.5e-15 56.1 1.0 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) Ketoacyl-synt_C PF02801.22 KFH41975.1 - 0.09 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Flavin_Reduct PF01613.18 KFH41976.1 - 8.3e-32 110.4 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.18 KFH41977.1 - 9.5e-10 37.9 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 KFH41978.1 - 1.8e-45 152.0 19.5 9.1e-09 35.8 0.5 7.9 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH41978.1 - 4.5e-07 30.1 0.1 0.38 11.1 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH41978.1 - 4.5e-07 28.9 0.3 0.00093 18.0 0.0 3.6 3 1 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFH41978.1 - 0.0011 17.8 0.0 0.35 9.6 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like Zn_clus PF00172.18 KFH41979.1 - 3.6e-08 33.4 12.4 6.2e-08 32.6 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH41979.1 - 0.00021 20.4 0.1 0.00039 19.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MBOAT PF03062.19 KFH41980.1 - 4.8e-38 131.4 8.9 5.1e-37 128.0 4.0 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 KFH41980.1 - 0.032 14.9 0.3 2.7 8.6 0.0 2.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF488 PF04343.13 KFH41981.1 - 1.1e-25 90.5 0.5 1.3e-25 90.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 DinB_2 PF12867.7 KFH41981.1 - 0.03 14.8 0.6 0.041 14.4 0.6 1.2 1 0 0 1 1 1 0 DinB superfamily DnaJ PF00226.31 KFH41982.1 - 1.9e-21 75.9 2.9 6.7e-21 74.2 2.9 2.0 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.22 KFH41983.1 - 5.2e-37 127.7 0.0 5.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFH41984.1 - 4e-51 174.2 0.0 4.5e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.11 KFH41984.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins 3HCDH_N PF02737.18 KFH41985.1 - 5.5e-33 114.3 0.0 1.4e-32 113.1 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFH41985.1 - 7.4e-10 39.3 0.1 1.7e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 KFH41985.1 - 0.072 12.4 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFH41985.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 KFH41985.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RIIa PF02197.17 KFH41985.1 - 0.17 11.6 0.1 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Aldedh PF00171.22 KFH41986.1 - 2.2e-137 458.3 0.2 2.5e-137 458.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UIM PF02809.20 KFH41986.1 - 0.076 13.0 1.2 0.68 10.0 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif MFS_1 PF07690.16 KFH41987.1 - 1.1e-41 143.0 45.0 2.7e-41 141.7 45.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41987.1 - 1.6e-12 47.1 24.1 7.6e-12 44.8 13.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KFH41987.1 - 2.8e-10 39.3 14.8 3.5e-10 38.9 14.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pro-rich_19 PF15455.6 KFH41987.1 - 0.15 11.1 0.6 0.25 10.4 0.6 1.2 1 0 0 1 1 1 0 Proline-rich 19 PSDC PF12588.8 KFH41988.1 - 5.8e-57 191.6 0.0 8.9e-57 191.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KFH41988.1 - 8.4e-35 120.1 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Metallophos PF00149.28 KFH41989.1 - 2.2e-06 28.3 0.6 3.2e-05 24.5 0.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH41989.1 - 0.012 15.8 0.0 2.8 8.1 0.0 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KFH41989.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.5 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily WD40 PF00400.32 KFH41991.1 - 1.5e-37 126.9 20.5 1.5e-07 32.0 0.3 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFH41991.1 - 1.7e-35 122.1 0.1 3.2e-29 101.8 0.0 2.2 1 1 1 2 2 2 2 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFH41991.1 - 1.4e-11 44.5 0.1 0.19 12.1 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KFH41991.1 - 1.8e-09 37.2 0.2 5.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 LisH Ge1_WD40 PF16529.5 KFH41991.1 - 0.0003 19.9 0.3 5.6 5.8 0.0 4.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFH41991.1 - 0.0037 17.2 0.0 0.24 11.2 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFH41991.1 - 0.17 10.6 0.0 20 3.7 0.0 3.0 2 1 0 2 2 2 0 Nup133 N terminal like MFS_1 PF07690.16 KFH41992.1 - 2.8e-43 148.2 33.9 2.8e-43 148.2 33.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH41992.1 - 1.4e-10 40.7 4.3 1.4e-10 40.7 4.3 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFH41992.1 - 1.7e-08 33.3 1.4 7.2e-08 31.3 0.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L31 PF01197.18 KFH41993.1 - 0.084 13.1 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L31 Oest_recep PF02159.15 KFH41993.1 - 1.3 9.5 7.5 0.14 12.7 1.4 2.3 1 1 0 2 2 2 0 Oestrogen receptor DUF5624 PF18538.1 KFH41994.1 - 5.4e-46 155.9 0.2 8.9e-46 155.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) EPTP PF03736.17 KFH41994.1 - 1.8e-45 152.6 5.0 1.1e-08 34.9 0.0 7.3 7 0 0 7 7 7 6 EPTP domain T2SSB PF16537.5 KFH41994.1 - 0.14 11.8 0.1 19 4.9 0.0 3.6 4 0 0 4 4 4 0 Type II secretion system protein B GMC_oxred_C PF05199.13 KFH41995.1 - 7.4e-30 104.4 0.0 1.2e-29 103.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFH41995.1 - 6.9e-29 101.2 0.0 2.1e-27 96.3 0.0 2.5 1 1 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFH41995.1 - 4e-05 23.0 0.0 0.00012 21.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH41995.1 - 0.00013 21.2 0.0 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFH41995.1 - 0.0005 20.3 0.5 0.0012 19.0 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFH41995.1 - 0.0021 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFH41995.1 - 0.0028 17.0 0.1 0.71 9.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH41995.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFH41995.1 - 0.039 13.5 0.1 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH41995.1 - 0.06 12.0 0.1 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Rossmann-like PF10727.9 KFH41995.1 - 0.068 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 KFH41995.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HSP90 PF00183.18 KFH41996.1 - 3.4e-106 356.2 18.5 1.8e-93 314.2 4.4 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KFH41996.1 - 9.1e-15 55.1 0.1 1.6e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFH41996.1 - 5.1e-10 39.3 0.1 1.2e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KFH41996.1 - 0.029 14.4 1.9 0.13 12.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF4695 PF15766.5 KFH41996.1 - 3.1 8.0 9.8 0.4 10.9 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Methyltransf_16 PF10294.9 KFH41998.1 - 2.7e-19 69.6 0.0 4.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFH41998.1 - 0.00046 20.8 0.0 0.0021 18.7 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 KFH41998.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFH41998.1 - 0.0008 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFH41998.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 KFH41998.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KFH41998.1 - 0.0099 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KFH41998.1 - 0.018 14.8 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KFH41998.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFH41998.1 - 0.05 14.4 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glutaredoxin PF00462.24 KFH42000.1 - 2.8e-16 59.5 0.0 4.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DAO PF01266.24 KFH42002.1 - 2.2e-27 96.6 0.4 2.8e-27 96.2 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFH42002.1 - 0.00022 21.7 1.0 0.00053 20.5 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH42002.1 - 0.00099 19.3 0.3 0.003 17.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH42002.1 - 0.0027 17.0 0.2 0.0056 15.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH42002.1 - 0.005 16.1 0.6 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.21 KFH42002.1 - 0.03 13.7 0.4 0.058 12.7 0.4 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KFH42002.1 - 0.054 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KFH42002.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH42002.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KFH42002.1 - 0.25 10.9 0.8 0.4 10.2 0.8 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pro_isomerase PF00160.21 KFH42003.1 - 7.7e-34 117.2 0.0 1.2e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFH42003.1 - 6.2e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3659 PF12396.8 KFH42003.1 - 0.046 13.6 0.4 0.097 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) G_glu_transpept PF01019.21 KFH42004.1 - 1.6e-172 574.8 0.0 1.9e-172 574.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Aminotran_4 PF01063.19 KFH42005.1 - 2.6e-27 96.1 0.0 3.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV PMI_typeI PF01238.21 KFH42006.1 - 1.6e-132 442.2 0.0 1.9e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I K_channel_TID PF07941.11 KFH42007.1 - 0.048 14.1 7.5 1.7 9.1 5.7 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TIG_2 PF18020.1 KFH42008.1 - 0.022 15.4 0.1 0.038 14.6 0.1 1.3 1 0 0 1 1 1 0 TIG domain found in plexin Fic PF02661.18 KFH42009.1 - 9.2e-08 32.9 0.2 1.8e-07 32.0 0.2 1.5 1 0 0 1 1 1 1 Fic/DOC family Ribosomal_S24e PF01282.19 KFH42010.1 - 1.3e-34 118.0 0.0 2.2e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Sugar_tr PF00083.24 KFH42011.1 - 7.8e-89 298.6 9.1 1.2e-88 298.0 9.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42011.1 - 1.2e-26 93.5 28.4 8.1e-26 90.8 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH42011.1 - 4.9e-08 31.9 3.0 4.9e-08 31.9 3.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Actin PF00022.19 KFH42012.1 - 3.5e-113 378.3 0.0 2.3e-112 375.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFH42012.1 - 0.015 14.2 0.0 0.17 10.6 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KFH42012.1 - 0.071 12.3 0.9 0.27 10.4 0.1 2.2 3 0 0 3 3 3 0 Putative actin-like family Arf PF00025.21 KFH42013.1 - 2.7e-75 251.6 0.2 3.1e-75 251.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFH42013.1 - 6.9e-14 52.1 0.0 9.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFH42013.1 - 6.2e-13 48.7 0.0 7.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFH42013.1 - 2.8e-12 46.5 2.5 1.6e-08 34.1 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFH42013.1 - 3.7e-11 42.8 0.0 4.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFH42013.1 - 6.7e-11 42.0 0.1 8.5e-11 41.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Methyltrn_RNA_3 PF02598.17 KFH42013.1 - 0.035 13.6 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase 6PF2K PF01591.18 KFH42013.1 - 0.039 13.3 0.2 0.084 12.2 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 KFH42013.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 GTP_cyclohydro2 PF00925.20 KFH42014.1 - 3.7e-62 208.7 0.0 5.2e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4419 PF14388.6 KFH42015.1 - 1e-38 133.5 0.1 1.1e-38 133.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) APG6_N PF17675.1 KFH42017.1 - 0.015 15.8 1.6 0.015 15.8 1.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region COG2 PF06148.11 KFH42017.1 - 0.073 13.2 3.6 5.5 7.1 0.5 2.2 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.18 KFH42017.1 - 0.58 10.0 6.9 1.9 8.3 6.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain G_glu_transpept PF01019.21 KFH42018.1 - 1.1e-137 460.0 0.0 1.2e-137 459.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FliT PF05400.13 KFH42019.1 - 0.094 13.5 2.4 0.58 11.0 1.3 2.2 2 0 0 2 2 2 0 Flagellar protein FliT PCRF PF03462.18 KFH42020.1 - 3e-44 151.2 0.0 6.3e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KFH42020.1 - 4e-35 120.3 2.1 4e-35 120.3 2.1 1.7 2 0 0 2 2 2 1 RF-1 domain CTP_transf_like PF01467.26 KFH42021.1 - 1.4e-19 70.7 0.0 9.1e-17 61.6 0.0 3.0 3 1 0 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFH42021.1 - 0.15 12.0 0.4 25 4.7 0.4 3.0 3 0 0 3 3 3 0 FAD synthetase Zn_clus PF00172.18 KFH42022.1 - 2.6e-08 33.8 7.5 2.6e-08 33.8 7.5 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KFH42026.1 - 5.1e-11 42.8 0.0 1.1e-10 41.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFH42026.1 - 3.7e-10 40.0 0.0 5.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFH42026.1 - 3.2e-08 33.8 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH42026.1 - 1.3e-06 28.3 0.1 2.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH42026.1 - 0.00083 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH42026.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Asp_Glu_race PF01177.22 KFH42027.1 - 0.00018 21.4 0.0 0.0019 18.1 0.0 1.9 1 1 1 2 2 2 2 Asp/Glu/Hydantoin racemase Pkinase PF00069.25 KFH42028.1 - 2.1e-56 191.2 0.0 2.4e-55 187.7 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42028.1 - 1.5e-26 93.3 0.0 4.6e-26 91.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Macoilin PF09726.9 KFH42028.1 - 0.51 8.8 1.3 0.65 8.5 1.3 1.2 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 KFH42028.1 - 1.8 7.9 14.4 2.9 7.2 14.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF755 PF05501.11 KFH42028.1 - 2.3 8.5 13.7 4.4 7.6 12.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ecl1 PF12855.7 KFH42028.1 - 2.9 9.0 17.5 0.68 11.1 11.0 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Caskin1-CID PF16600.5 KFH42028.1 - 4.7 7.9 8.1 5.1 7.8 3.5 2.9 3 0 0 3 3 3 0 Caskin1 CASK-interaction domain DUF1325 PF07039.11 KFH42029.1 - 1.6e-37 128.6 0.1 2.5e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 KFH42029.1 - 0.12 12.4 0.1 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Cerato-platanin PF07249.12 KFH42030.1 - 0.00083 19.5 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin cwf21 PF08312.12 KFH42031.1 - 1.8e-17 63.2 13.7 5.2e-17 61.7 13.7 1.8 1 0 0 1 1 1 1 cwf21 domain DUF1129 PF06570.11 KFH42031.1 - 0.1 12.1 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MPS2 PF17060.5 KFH42031.1 - 0.11 11.8 4.5 0.13 11.5 4.5 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Trans_reg_C PF00486.28 KFH42031.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.5 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal GvpG PF05120.12 KFH42031.1 - 0.49 10.4 9.2 1.2 9.2 1.7 2.5 2 1 0 2 2 2 0 Gas vesicle protein G RhoGAP PF00620.27 KFH42032.1 - 2.6e-36 124.7 0.0 4.1e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Nup188_C PF18378.1 KFH42033.1 - 2.9e-157 523.2 0.0 4.4e-157 522.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KFH42033.1 - 8.8e-38 129.8 1.5 2.7e-31 108.4 2.7 2.6 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Abhydrolase_1 PF00561.20 KFH42034.1 - 2.4e-13 50.4 0.0 2.9e-09 37.0 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH42034.1 - 4.7e-09 37.2 0.0 5.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH42034.1 - 7.1e-07 28.7 0.0 1.1e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFH42034.1 - 6.7e-05 21.7 0.0 0.0002 20.2 0.0 1.9 1 1 0 1 1 1 1 Ndr family DLH PF01738.18 KFH42034.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Aminotran_3 PF00202.21 KFH42035.1 - 2e-119 398.9 0.0 2.3e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KFH42035.1 - 0.00014 21.3 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFH42035.1 - 0.058 12.6 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HeLo PF14479.6 KFH42036.1 - 9e-12 45.3 0.0 2.2e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Prion-inhibition and propagation SH3_1 PF00018.28 KFH42037.1 - 5.4e-15 54.7 0.1 8.6e-15 54.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH42037.1 - 9.1e-10 38.2 0.1 1.4e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH42037.1 - 1.2e-08 34.5 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.11 KFH42037.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) zf-CCCH PF00642.24 KFH42038.1 - 9e-05 22.3 0.3 0.00015 21.5 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 KFH42038.1 - 0.009 15.7 3.2 0.015 15.0 3.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain OSK PF17182.4 KFH42038.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 OSK domain zf_CCCH_4 PF18345.1 KFH42038.1 - 0.25 11.5 0.1 0.4 10.8 0.1 1.3 1 0 0 1 1 1 0 Zinc finger domain Allexi_40kDa PF05549.11 KFH42038.1 - 1.1 8.7 7.5 0.3 10.6 1.4 2.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.22 KFH42038.1 - 7.6 6.8 13.9 0.75 10.1 4.0 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RRM_1 PF00076.22 KFH42039.1 - 1.8e-09 37.3 0.0 6e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KFH42040.1 - 6e-26 91.4 0.0 3.8e-22 78.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42040.1 - 1.7e-19 70.2 0.0 1.5e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 KFH42040.1 - 1.4e-16 60.8 0.2 1.5e-05 25.5 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH42040.1 - 1.4e-14 54.3 0.6 0.0072 16.9 0.0 5.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) APH PF01636.23 KFH42040.1 - 9.9e-09 35.5 9.7 0.0074 16.2 0.2 4.9 3 2 2 5 5 5 3 Phosphotransferase enzyme family Kdo PF06293.14 KFH42040.1 - 2.9e-07 30.0 1.0 0.00012 21.5 0.1 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.30 KFH42040.1 - 2.2e-06 27.9 1.9 0.55 10.8 0.0 6.0 7 0 0 7 7 6 2 Ankyrin repeat Ank_5 PF13857.6 KFH42040.1 - 2.7e-06 27.5 6.1 0.012 15.9 0.0 5.6 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Sel1 PF08238.12 KFH42040.1 - 4.4e-05 24.0 0.0 0.00019 22.0 0.0 2.3 1 0 0 1 1 1 1 Sel1 repeat Ank_3 PF13606.6 KFH42040.1 - 0.00036 20.8 0.2 19 6.2 0.0 5.7 5 0 0 5 5 5 0 Ankyrin repeat RIO1 PF01163.22 KFH42040.1 - 0.0044 16.6 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 RIO1 family F-box_4 PF15966.5 KFH42040.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 F-box DUF2895 PF11444.8 KFH42040.1 - 0.046 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) F-box PF00646.33 KFH42040.1 - 0.07 13.0 0.3 0.87 9.5 0.5 2.5 2 0 0 2 2 2 0 F-box domain Choline_kinase PF01633.20 KFH42040.1 - 0.072 12.7 0.0 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sod_Cu PF00080.20 KFH42041.1 - 2.1e-46 157.6 3.5 2.4e-46 157.4 3.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MOSC PF03473.17 KFH42042.1 - 3.7e-25 88.5 0.0 5.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFH42042.1 - 1.9e-12 47.1 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3716 PF12511.8 KFH42043.1 - 1.5e-16 60.1 7.2 2.6e-16 59.4 7.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Packaging_FI PF14000.6 KFH42043.1 - 0.03 14.8 0.1 0.049 14.1 0.1 1.2 1 0 0 1 1 1 0 DNA packaging protein FI TAL_FSA PF00923.19 KFH42044.1 - 1.2e-93 313.6 1.2 1.5e-93 313.3 1.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Cas_VVA1548 PF09652.10 KFH42044.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) Pet191_N PF10203.9 KFH42045.1 - 1.2e-27 96.0 4.5 1.5e-27 95.7 4.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KFH42045.1 - 0.018 14.9 0.3 0.021 14.7 0.3 1.1 1 0 0 1 1 1 0 COBRA-like protein NDUF_B7 PF05676.13 KFH42045.1 - 0.046 13.4 1.0 1.7 8.4 0.0 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PAN_3 PF08277.12 KFH42045.1 - 0.049 13.4 0.4 0.078 12.8 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 KFH42045.1 - 0.14 12.2 9.8 0.27 11.3 1.1 2.9 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KFH42045.1 - 0.25 11.4 5.3 1.3 9.0 0.9 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like IGPS PF00218.21 KFH42046.1 - 3e-94 314.9 0.2 4.8e-94 314.3 0.2 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KFH42046.1 - 1.5e-47 161.9 0.1 1.1e-42 146.0 0.0 2.5 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KFH42046.1 - 1.4e-45 155.5 0.0 5.6e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFH42046.1 - 3.9e-05 23.5 0.5 0.00017 21.4 0.1 2.2 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 KFH42046.1 - 0.0012 18.6 0.8 0.24 11.2 0.1 2.8 3 0 0 3 3 3 2 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KFH42046.1 - 0.014 14.4 0.2 0.084 11.9 0.0 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KFH42046.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Histidine biosynthesis protein Use1 PF09753.9 KFH42047.1 - 3e-09 37.0 0.0 7.5e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Membrane fusion protein Use1 Macoilin PF09726.9 KFH42047.1 - 3.1 6.3 6.5 0.55 8.7 0.5 1.9 2 0 0 2 2 2 0 Macoilin family Glyco_transf_22 PF03901.17 KFH42048.1 - 9.6e-77 259.0 16.1 1.2e-76 258.6 16.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-Tim10_DDP PF02953.15 KFH42049.1 - 1.3e-18 66.4 1.9 1.3e-18 66.4 1.9 1.6 1 1 0 2 2 2 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 KFH42049.1 - 0.0052 16.4 1.9 0.0053 16.4 1.9 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF842 PF05811.13 KFH42049.1 - 0.08 12.6 5.8 1.4 8.6 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) G-alpha PF00503.20 KFH42050.1 - 1.1e-124 416.2 2.5 1.3e-124 415.9 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFH42050.1 - 3.7e-15 55.8 2.0 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KFH42050.1 - 8.5e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KFH42050.1 - 0.0019 17.6 2.9 0.11 11.9 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KFH42050.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KFH42050.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KFH42050.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KFH42050.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KFH42050.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KFH42050.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase MmgE_PrpD PF03972.14 KFH42051.1 - 1.3e-146 488.6 0.0 1.5e-146 488.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF2937 PF11157.8 KFH42051.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) CMS1 PF14617.6 KFH42052.1 - 3e-82 275.8 1.7 3.2e-82 275.7 1.7 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFH42052.1 - 6.1e-07 29.4 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_1 PF00561.20 KFH42053.1 - 4.7e-24 85.4 0.1 1.3e-23 83.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFH42053.1 - 1e-21 76.2 0.0 1.9e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFH42053.1 - 1.1e-06 28.1 0.0 0.00024 20.5 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KFH42053.1 - 0.00075 19.2 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ras PF00071.22 KFH42054.1 - 1e-53 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH42054.1 - 9.8e-21 74.2 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42054.1 - 1.4e-05 24.6 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Myosin_head PF00063.21 KFH42055.1 - 5.7e-266 884.1 0.0 1.3e-265 882.9 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KFH42055.1 - 9e-11 41.4 2.6 2.8e-10 39.9 2.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFH42055.1 - 0.056 13.7 0.0 0.056 13.7 0.0 5.0 3 0 0 3 3 3 0 AAA domain Myosin_tail_1 PF01576.19 KFH42055.1 - 0.064 11.1 282.5 0.12 10.1 18.2 6.7 2 2 2 5 5 5 0 Myosin tail SNase PF00565.17 KFH42056.1 - 4.1e-68 226.7 0.3 3.6e-19 69.2 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KFH42056.1 - 4.1e-25 88.2 0.0 8.1e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KFH42056.1 - 0.00011 21.6 0.0 0.00026 20.3 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KFH42056.1 - 0.011 16.2 0.3 0.15 12.5 0.1 2.9 3 0 0 3 3 3 0 Agenet domain D123 PF07065.14 KFH42057.1 - 2.3e-116 388.3 0.0 2.7e-116 388.0 0.0 1.0 1 0 0 1 1 1 1 D123 CDC45 PF02724.14 KFH42057.1 - 0.22 9.8 4.6 0.026 12.8 0.5 1.4 2 0 0 2 2 2 0 CDC45-like protein Metallophos PF00149.28 KFH42058.1 - 1.3e-10 42.1 0.1 2.2e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH42058.1 - 1.5e-06 28.6 0.2 1.4e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain BRCT PF00533.26 KFH42059.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Glyco_hydro_11 PF00457.17 KFH42060.1 - 6.2e-72 241.0 14.9 7.1e-72 240.8 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 F1F0-ATPsyn_F PF10791.9 KFH42061.1 - 6.2e-41 138.8 0.3 7.1e-41 138.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KFH42061.1 - 0.014 15.7 0.1 0.017 15.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f PAP_assoc PF03828.19 KFH42062.1 - 5.2e-16 58.6 0.0 5e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFH42062.1 - 0.00017 21.8 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HYLS1_C PF15311.6 KFH42062.1 - 0.018 15.8 1.5 0.51 11.1 0.1 2.9 3 0 0 3 3 3 0 Hydrolethalus syndrome protein 1 C-terminus Thiamine_BP PF01910.17 KFH42062.1 - 0.13 12.2 0.0 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 Thiamine-binding protein HNH_2 PF13391.6 KFH42063.1 - 2.4e-09 37.2 0.1 6.2e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C3HC4_2 PF13923.6 KFH42064.1 - 6e-13 48.4 9.6 6e-13 48.4 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH42064.1 - 1.5e-08 34.3 10.2 1.5e-08 34.3 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH42064.1 - 1.4e-07 31.4 6.8 1.4e-07 31.4 6.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH42064.1 - 1.5e-07 31.3 8.9 1.5e-07 31.3 8.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFH42064.1 - 1.8e-07 30.9 12.2 2.5e-07 30.4 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH42064.1 - 1e-06 29.0 14.7 3.4e-06 27.3 9.4 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KFH42064.1 - 7.4e-06 25.7 12.2 0.00019 21.2 7.9 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFH42064.1 - 1.1e-05 25.6 3.7 1.1e-05 25.6 3.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFH42064.1 - 3.5e-05 23.9 9.9 3.5e-05 23.9 9.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFH42064.1 - 5.9e-05 22.8 4.0 0.00012 21.9 4.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SAP PF02037.27 KFH42064.1 - 0.00029 20.5 0.1 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 SAP domain Mob_synth_C PF06463.13 KFH42064.1 - 0.00047 20.1 1.3 0.0012 18.8 1.3 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_10 PF16685.5 KFH42064.1 - 0.00049 20.2 3.8 0.0011 19.1 3.8 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KFH42064.1 - 0.036 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-P11 PF03854.14 KFH42064.1 - 0.21 11.3 6.3 0.54 10.0 6.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KFH42064.1 - 0.48 10.5 5.2 0.24 11.4 1.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFH42064.1 - 0.94 9.3 14.4 0.27 11.1 7.7 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Fer4_11 PF13247.6 KFH42064.1 - 1.3 9.2 5.7 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain MOZ_SAS PF01853.18 KFH42065.1 - 2.4e-79 265.2 0.1 3.3e-79 264.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFH42065.1 - 2.7e-22 78.1 1.1 5.1e-22 77.2 1.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFH42065.1 - 1.6e-17 63.1 0.0 3.7e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFH42065.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH42065.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 KFH42066.1 - 1.8e-09 37.0 38.1 1.7e-06 27.2 9.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42066.1 - 4.2e-06 25.9 0.2 4.2e-06 25.9 0.2 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Ecm33 PF12454.8 KFH42067.1 - 0.12 12.6 0.5 0.12 12.6 0.5 1.8 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Aminotran_1_2 PF00155.21 KFH42070.1 - 2.8e-23 82.7 0.0 4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_10 PF00331.20 KFH42071.1 - 1.4e-105 353.0 0.8 1.6e-105 352.8 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KFH42071.1 - 1.8e-09 37.4 8.1 1.8e-09 37.4 8.1 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain GYF_2 PF14237.6 KFH42071.1 - 0.03 14.1 0.4 0.79 9.6 0.1 2.5 2 0 0 2 2 2 0 GYF domain 2 Glyco_hydro_42 PF02449.15 KFH42071.1 - 0.12 11.7 0.3 0.62 9.3 0.1 1.9 1 1 1 2 2 2 0 Beta-galactosidase WxL PF13731.6 KFH42071.1 - 0.13 12.3 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Ras PF00071.22 KFH42072.1 - 9.5e-60 200.9 0.4 1.2e-59 200.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH42072.1 - 1.5e-37 128.4 0.1 2.4e-37 127.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42072.1 - 1.8e-18 66.6 0.3 2.2e-18 66.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH42072.1 - 1e-06 28.4 0.1 6.4e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFH42072.1 - 9.3e-06 25.2 0.1 1.4e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFH42072.1 - 1.6e-05 24.9 0.1 3.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFH42072.1 - 1.7e-05 24.3 0.4 2.2e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFH42072.1 - 0.00016 21.6 0.1 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KFH42072.1 - 0.0038 17.0 0.1 0.012 15.5 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 KFH42072.1 - 0.031 13.9 0.7 0.043 13.4 0.7 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 KFH42072.1 - 0.042 14.5 0.1 0.082 13.5 0.1 1.4 1 0 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 KFH42072.1 - 0.062 13.5 0.0 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_28 PF13521.6 KFH42072.1 - 0.07 13.4 0.1 3.7 7.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain ETC_C1_NDUFA4 PF04800.12 KFH42073.1 - 6e-36 122.6 0.5 1.2e-35 121.7 0.5 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region NIR_SIR PF01077.22 KFH42074.1 - 1.7e-54 183.6 0.1 5.4e-50 169.0 0.1 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KFH42074.1 - 8.8e-30 102.4 0.0 7.2e-15 54.6 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KFH42074.1 - 1.9e-27 96.3 0.1 6e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.19 KFH42074.1 - 1.7e-06 28.0 0.1 4.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pyr_redox_2 PF07992.14 KFH42075.1 - 8.4e-45 153.2 0.0 1.6e-44 152.3 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH42075.1 - 6.2e-14 52.3 0.6 4.6e-10 39.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KFH42075.1 - 6.7e-07 28.4 0.3 6.7e-07 28.4 0.3 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFH42075.1 - 1.3e-05 24.8 0.7 4.1e-05 23.2 0.7 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFH42075.1 - 0.00018 21.9 0.1 0.00042 20.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFH42075.1 - 0.00098 18.5 1.1 0.00098 18.5 1.1 2.0 2 0 0 2 2 2 1 EF hand FAD_binding_2 PF00890.24 KFH42075.1 - 0.011 14.9 0.4 3.1 6.8 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.6 KFH42075.1 - 0.02 14.2 0.0 0.51 9.5 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase bVLRF1 PF18826.1 KFH42075.1 - 0.051 13.4 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Mito_fiss_reg PF05308.11 KFH42076.1 - 0.13 12.3 5.2 0.16 12.1 5.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KFH42076.1 - 5.3 6.4 7.4 6.9 6.0 7.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNase_H2_suC PF08615.11 KFH42077.1 - 3.9e-22 78.9 0.0 6.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_M50B PF13398.6 KFH42078.1 - 7.8e-61 205.2 19.6 9.4e-61 204.9 19.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KFH42078.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 MLANA PF14991.6 KFH42078.1 - 0.55 10.5 4.4 0.18 12.1 0.7 2.0 1 1 1 2 2 2 0 Protein melan-A SecD_SecF PF02355.16 KFH42078.1 - 1.7 8.0 11.0 1.6 8.1 0.5 2.8 3 0 0 3 3 3 0 Protein export membrane protein YlaC PF10777.9 KFH42078.1 - 9 6.1 6.7 0.85 9.4 0.3 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC XPG_I_2 PF12813.7 KFH42080.1 - 1.7e-49 168.6 0.0 2.5e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KFH42080.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Glyco_hydro_18 PF00704.28 KFH42081.1 - 1.3e-20 74.4 0.1 7.2e-20 71.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TRAPPC-Trs85 PF12739.7 KFH42082.1 - 3e-115 385.4 0.6 2.1e-114 382.7 0.5 1.9 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RNase_T PF00929.24 KFH42083.1 - 8.5e-18 65.4 0.0 1.4e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFH42083.1 - 0.00073 19.3 0.0 0.002 17.8 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease LOR PF04525.12 KFH42085.1 - 2.6e-23 82.6 0.0 3.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related UbiD PF01977.16 KFH42085.1 - 0.029 13.2 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase APH PF01636.23 KFH42086.1 - 1.1e-11 45.1 1.2 1.9e-10 41.1 0.9 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH42086.1 - 0.00039 20.1 1.1 0.00052 19.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Snf7 PF03357.21 KFH42087.1 - 9.9e-20 70.8 16.8 1.5e-19 70.2 16.8 1.3 1 0 0 1 1 1 1 Snf7 E3_binding PF02817.17 KFH42087.1 - 0.054 13.8 0.2 0.15 12.4 0.2 1.8 1 0 0 1 1 1 0 e3 binding domain PspA_IM30 PF04012.12 KFH42087.1 - 0.85 9.2 31.3 0.43 10.1 25.7 2.7 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.8 KFH42087.1 - 2.5 8.5 15.1 2 8.8 3.2 2.8 3 0 0 3 3 3 0 YlqD protein IATP PF04568.12 KFH42087.1 - 3.8 8.0 9.8 0.47 10.9 4.6 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP End3 PF12761.7 KFH42087.1 - 5.9 7.0 12.4 4.9 7.3 1.0 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Bud13 PF09736.9 KFH42088.1 - 1.6e-52 177.7 16.5 1.6e-52 177.7 16.5 2.6 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4350 PF14258.6 KFH42089.1 - 0.00013 22.3 0.0 0.00053 20.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) TniB PF05621.11 KFH42089.1 - 0.0069 15.8 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Glyco_hydro_42M PF08532.10 KFH42089.1 - 0.014 14.9 0.1 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain Glyco_hydro_125 PF06824.11 KFH42090.1 - 2.6e-179 596.4 0.0 3e-179 596.2 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Kei1 PF08552.11 KFH42091.1 - 8.8e-53 179.0 13.8 2.7e-51 174.2 13.8 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 KFH42091.1 - 9.9 6.3 10.2 0.45 10.6 3.2 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CDC27 PF09507.10 KFH42092.1 - 6.6e-73 246.5 32.1 1.5e-72 245.4 32.1 1.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Methyltransf_25 PF13649.6 KFH42093.1 - 2.8e-07 31.2 0.2 6.1e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH42093.1 - 7.3e-07 29.8 0.1 1.4e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH42093.1 - 2.7e-05 24.9 0.0 3.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH42093.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRK PF00485.18 KFH42094.1 - 3.3e-56 190.2 0.0 5.3e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KFH42094.1 - 3e-40 137.9 0.0 4.4e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KFH42094.1 - 2.1e-06 28.3 0.0 5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFH42094.1 - 8.5e-06 26.2 0.8 0.15 12.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain CPT PF07931.12 KFH42094.1 - 0.00023 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KFH42094.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 KFH42094.1 - 0.0043 17.2 0.2 0.039 14.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFH42094.1 - 0.0078 16.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH42094.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KFH42094.1 - 0.013 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KFH42094.1 - 0.015 15.8 0.3 0.044 14.3 0.1 1.8 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.22 KFH42094.1 - 0.015 15.7 0.0 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 KFH42094.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KFH42094.1 - 0.017 14.9 0.1 0.054 13.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFH42094.1 - 0.045 13.8 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SKI PF01202.22 KFH42094.1 - 0.07 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase APS_kinase PF01583.20 KFH42094.1 - 0.08 12.8 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 KFH42094.1 - 0.11 12.9 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KFH42094.1 - 0.15 12.1 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain dNK PF01712.19 KFH42094.1 - 0.16 11.8 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 KFH42094.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SRP1_TIP1 PF00660.17 KFH42094.1 - 0.18 11.9 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Seripauperin and TIP1 family CoaE PF01121.20 KFH42094.1 - 0.19 11.4 0.3 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Pribosyltran_N PF13793.6 KFH42095.1 - 5.2e-43 145.7 0.0 8.4e-42 141.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFH42095.1 - 1e-34 120.2 0.2 5.2e-29 101.6 0.1 2.7 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFH42095.1 - 1e-08 34.9 0.0 5.1e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain DUF2300 PF10062.9 KFH42095.1 - 0.16 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Chitin_synth_1 PF01644.17 KFH42096.1 - 8.3e-78 260.0 0.1 1.3e-77 259.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFH42096.1 - 2.8e-27 94.4 0.1 5.3e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFH42096.1 - 2e-24 86.2 5.3 1.4e-20 73.4 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFH42096.1 - 7.2e-09 35.8 0.2 7.2e-09 35.8 0.2 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Nop53 PF07767.11 KFH42097.1 - 1e-112 377.5 35.2 1.2e-112 377.3 35.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4709 PF15821.5 KFH42097.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) MCM PF00493.23 KFH42098.1 - 5.3e-104 346.2 0.2 9.1e-104 345.4 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFH42098.1 - 1.2e-39 135.0 0.7 2.2e-39 134.2 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KFH42098.1 - 9e-33 112.7 0.2 2.3e-32 111.4 0.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KFH42098.1 - 6.4e-24 84.2 2.3 9.9e-24 83.6 0.3 2.5 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 KFH42098.1 - 5.8e-23 81.5 0.0 1.8e-22 79.9 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH42098.1 - 2.7e-07 30.2 0.0 8.8e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFH42098.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KFH42098.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH42098.1 - 0.13 12.3 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 KFH42098.1 - 0.18 12.0 1.5 0.59 10.3 1.5 1.9 1 0 0 1 1 1 0 GidA associated domain DJ-1_PfpI PF01965.24 KFH42099.1 - 1e-16 61.2 0.0 1.7e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFH42099.1 - 4.6e-06 26.4 0.0 1.1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KFH42099.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 KFH42099.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases PHA_gran_rgn PF09650.10 KFH42099.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Glyoxalase PF00903.25 KFH42100.1 - 5.9e-07 29.7 0.0 1.2e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFH42100.1 - 6.3e-05 23.7 0.0 0.00015 22.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFH42100.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ribonucleas_3_3 PF14622.6 KFH42101.1 - 2.5e-21 76.2 0.0 4.5e-21 75.3 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like 2-Hacid_dh_C PF02826.19 KFH42102.1 - 1.3e-32 112.5 0.0 1.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH42102.1 - 2.2e-10 40.3 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFH42102.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.7 KFH42104.1 - 5.1e-25 87.9 0.2 1.8e-11 44.4 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH42104.1 - 1e-14 54.3 9.8 1.5e-05 25.2 0.1 6.8 3 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH42104.1 - 3.1e-13 48.6 8.9 0.0055 17.1 0.0 8.1 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 KFH42104.1 - 1.3e-12 47.9 9.0 1.2e-06 28.9 0.1 5.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH42104.1 - 1.6e-12 47.3 14.4 0.012 16.0 0.0 7.2 7 1 0 7 7 7 3 Ankyrin repeat Tim17 PF02466.19 KFH42104.1 - 0.075 13.4 0.0 5.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CHAP PF05257.16 KFH42104.1 - 0.1 13.2 0.2 6.4 7.4 0.0 3.2 3 0 0 3 3 3 0 CHAP domain Thioesterase PF00975.20 KFH42105.1 - 7.1e-14 52.5 0.0 8.2e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFH42105.1 - 7.8e-07 29.9 1.6 3.5e-06 27.8 1.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFH42105.1 - 5.4e-05 23.1 0.0 8.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFH42105.1 - 0.001 18.8 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFH42105.1 - 0.0012 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH42105.1 - 0.045 13.0 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFH42105.1 - 0.054 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KFH42105.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UvdE PF03851.14 KFH42106.1 - 6.3e-107 356.9 0.0 1e-106 356.2 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE SET PF00856.28 KFH42106.1 - 1.6e-17 64.4 0.0 4.2e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KFH42106.1 - 7.9e-07 29.8 0.1 2.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding AKNA PF12443.8 KFH42106.1 - 0.016 15.8 0.5 0.033 14.8 0.5 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor IF3_C PF00707.22 KFH42107.1 - 9.6e-11 41.5 0.3 1.9e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KFH42107.1 - 2.1e-07 30.8 4.0 3.2e-07 30.2 4.0 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF4808 PF16066.5 KFH42107.1 - 0.029 14.9 0.1 0.07 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Formyl_trans_N PF00551.19 KFH42108.1 - 2.8e-40 138.0 0.0 3.3e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 KFH42108.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Amidase PF01425.21 KFH42109.1 - 4.3e-20 72.1 0.1 1.7e-19 70.2 0.1 1.8 2 0 0 2 2 2 1 Amidase ACC_epsilon PF13822.6 KFH42110.1 - 0.039 14.6 0.1 0.061 14.0 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Pectate_lyase_3 PF12708.7 KFH42110.1 - 0.049 13.5 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Pectate lyase superfamily protein MF_alpha_N PF05436.11 KFH42110.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Hce2 PF14856.6 KFH42111.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor LpoB PF13036.6 KFH42111.1 - 0.24 11.3 0.7 0.51 10.3 0.5 1.7 1 1 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Fungal_trans PF04082.18 KFH42112.1 - 4.8e-13 48.7 0.0 7.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42112.1 - 0.014 15.6 7.6 0.027 14.6 7.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.19 KFH42113.1 - 4.7e-39 134.0 0.1 5.8e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KFH42113.1 - 2.3e-09 36.9 0.0 6.9e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KFH42113.1 - 0.00033 20.6 0.0 0.00088 19.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 KFH42113.1 - 0.069 13.3 0.0 13 5.9 0.0 2.4 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 KFH42115.1 - 1.9e-75 254.5 24.9 2.4e-75 254.1 24.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42115.1 - 5.7e-16 58.4 38.1 2.1e-11 43.4 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HAT_KAT11 PF08214.11 KFH42116.1 - 1.2e-97 327.3 0.0 2.2e-97 326.5 0.0 1.4 2 0 0 2 2 2 1 Histone acetylation protein SUIM_assoc PF16619.5 KFH42116.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ketoacyl-synt PF00109.26 KFH42117.1 - 4.7e-67 226.2 0.0 1.3e-66 224.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH42117.1 - 7.1e-60 202.0 0.7 1.9e-59 200.6 0.7 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH42117.1 - 3.2e-53 180.9 0.0 5.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH42117.1 - 3.2e-48 164.9 0.2 6.1e-48 164.0 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH42117.1 - 1.1e-37 128.6 0.4 3.3e-37 127.1 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH42117.1 - 5.5e-22 79.2 0.0 2.1e-17 64.4 0.0 3.4 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH42117.1 - 4.4e-19 68.7 0.0 5.7e-17 61.9 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH42117.1 - 5.1e-19 68.9 0.1 1.8e-18 67.1 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH42117.1 - 3e-15 56.6 0.3 5e-10 39.8 0.0 2.9 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFH42117.1 - 1.2e-14 54.2 0.4 2.1e-13 50.1 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFH42117.1 - 1.8e-11 44.6 0.1 1.9e-10 41.3 0.0 3.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH42117.1 - 2.9e-11 43.5 0.0 5.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH42117.1 - 1e-09 38.9 0.0 8.2e-09 36.0 0.0 2.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH42117.1 - 1.7e-09 37.7 0.0 4.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH42117.1 - 6.3e-08 32.2 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SAT PF16073.5 KFH42117.1 - 1e-07 31.9 0.3 2.7e-07 30.6 0.3 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short_C2 PF13561.6 KFH42117.1 - 2.7e-06 27.1 0.7 1.2e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KFH42117.1 - 2.7e-06 27.7 0.1 7.2e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_33 PF10017.9 KFH42117.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 KFH42117.1 - 0.0021 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KFH42117.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DREV PF05219.12 KFH42117.1 - 0.044 12.9 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase baeRF_family2 PF18844.1 KFH42117.1 - 9.4 6.3 7.4 36 4.4 0.0 4.4 4 1 1 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 2 zf-RING_2 PF13639.6 KFH42118.1 - 3.3e-09 36.9 2.7 2.6e-07 30.9 0.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFH42118.1 - 5.2e-07 29.9 2.6 6e-07 29.7 0.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFH42118.1 - 5e-05 23.1 0.9 5e-05 23.1 0.9 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH42118.1 - 0.00014 21.6 3.9 0.013 15.2 0.1 2.9 3 0 0 3 3 3 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFH42118.1 - 0.00016 21.7 0.8 0.00029 20.8 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFH42118.1 - 0.00018 21.4 0.6 0.0031 17.4 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFH42118.1 - 0.00021 21.1 0.2 0.00021 21.1 0.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFH42118.1 - 0.0027 17.3 0.6 0.0027 17.3 0.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KFH42118.1 - 0.0027 17.5 1.3 0.05 13.5 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH42118.1 - 0.0058 16.5 2.1 0.11 12.4 0.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KFH42118.1 - 0.047 13.9 5.3 1.8 8.8 3.5 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KFH42118.1 - 0.064 13.3 0.1 0.064 13.3 0.1 3.3 3 0 0 3 3 3 0 RING-type zinc-finger AMP-binding PF00501.28 KFH42119.1 - 8.2e-62 209.2 0.0 1.2e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH42119.1 - 6.7e-15 55.8 0.1 3.3e-14 53.6 0.0 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFH42120.1 - 0 1522.4 0.4 2.1e-77 260.5 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KFH42120.1 - 0 1030.4 0.0 1.1e-58 199.0 0.0 8.9 8 1 0 8 8 8 8 Condensation domain PP-binding PF00550.25 KFH42120.1 - 6.6e-75 247.4 9.4 3.3e-10 40.2 0.0 8.8 8 0 0 8 8 8 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH42120.1 - 3.9e-13 50.2 0.0 0.026 15.5 0.0 6.6 6 0 0 6 6 6 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KFH42120.1 - 0.00037 19.3 0.0 5.3 5.6 0.0 4.2 4 0 0 4 4 4 2 Transferase family AATase PF07247.12 KFH42120.1 - 0.22 10.0 1.0 44 2.4 0.0 4.0 5 0 0 5 5 5 0 Alcohol acetyltransferase SRP54 PF00448.22 KFH42121.1 - 6.6e-76 254.3 1.9 6.6e-76 254.3 1.9 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFH42121.1 - 2.5e-31 108.2 5.6 2.5e-31 108.2 5.6 3.7 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFH42121.1 - 6.7e-16 58.3 0.3 2.1e-15 56.7 0.3 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFH42121.1 - 3.6e-08 33.2 0.6 1.5e-07 31.2 0.4 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFH42121.1 - 2.4e-06 28.0 2.1 2.6e-06 27.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH42121.1 - 4.9e-05 23.5 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH42121.1 - 0.00032 21.1 0.0 0.00065 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KFH42121.1 - 0.00047 19.2 0.9 0.0027 16.7 0.9 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 KFH42121.1 - 0.0011 18.5 1.4 2.5 7.5 1.3 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFH42121.1 - 0.0013 18.8 0.6 0.034 14.2 0.3 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KFH42121.1 - 0.0013 18.4 0.1 0.0041 16.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFH42121.1 - 0.0014 19.0 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFH42121.1 - 0.0018 18.3 0.0 0.0085 16.1 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KFH42121.1 - 0.002 18.0 0.2 0.0088 15.9 0.0 2.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KFH42121.1 - 0.0028 17.6 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KFH42121.1 - 0.0056 17.2 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFH42121.1 - 0.0058 16.6 0.6 0.33 10.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 KFH42121.1 - 0.0065 16.2 1.6 0.024 14.3 0.1 2.5 3 0 0 3 3 2 1 Thymidylate kinase Zeta_toxin PF06414.12 KFH42121.1 - 0.0099 15.2 0.0 0.025 13.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 KFH42121.1 - 0.012 15.4 0.3 0.048 13.4 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KFH42121.1 - 0.022 15.0 0.2 0.048 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KFH42121.1 - 0.026 13.8 0.1 0.046 13.0 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Cytidylate_kin PF02224.18 KFH42121.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 KFH42121.1 - 0.066 12.9 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFH42121.1 - 0.088 12.7 2.0 1 9.3 2.0 2.2 1 1 0 1 1 1 0 NTPase Arf PF00025.21 KFH42121.1 - 0.09 12.2 0.4 0.32 10.4 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA PF00004.29 KFH42121.1 - 0.12 12.9 0.5 0.54 10.7 0.5 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KFH42121.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Torsin SKA2 PF16740.5 KFH42121.1 - 0.28 11.0 4.8 10 6.0 1.7 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ArsA_ATPase PF02374.15 KFH42121.1 - 1.6 7.8 5.2 0.6 9.2 0.0 2.7 2 1 0 2 2 2 0 Anion-transporting ATPase Ank_2 PF12796.7 KFH42122.1 - 6.2e-08 33.1 0.0 0.00012 22.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH42122.1 - 0.0019 18.5 0.0 17 6.4 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat DUF719 PF05334.13 KFH42122.1 - 0.0055 16.9 0.1 0.0075 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF719) Ank_4 PF13637.6 KFH42122.1 - 0.025 15.1 0.1 19 6.0 0.0 3.1 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH42122.1 - 0.026 14.9 0.0 1.8 9.0 0.0 3.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Alb1 PF09135.11 KFH42123.1 - 5.9e-29 101.0 12.7 8.4e-29 100.5 12.7 1.2 1 0 0 1 1 1 1 Alb1 MAM33 PF02330.16 KFH42123.1 - 0.02 14.8 2.1 0.026 14.5 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein Adap_comp_sub PF00928.21 KFH42124.1 - 1.9e-91 306.1 0.0 3.1e-91 305.4 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFH42124.1 - 5e-08 33.0 0.3 8.3e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.10 KFH42125.1 - 1.7e-41 142.8 6.1 1.5e-29 103.5 0.5 3.4 2 1 1 3 3 3 3 Transcription factor Opi1 GldM_N PF12081.8 KFH42125.1 - 0.056 13.5 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Thymidylate_kin PF02223.17 KFH42126.1 - 5e-41 140.4 0.0 6.5e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KFH42126.1 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH42126.1 - 0.035 14.6 0.0 0.13 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFH42126.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KdpD PF02702.17 KFH42126.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain dNK PF01712.19 KFH42126.1 - 0.13 12.1 0.0 1.2 9.0 0.0 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase Zn_clus PF00172.18 KFH42127.1 - 1.1e-08 35.0 9.5 2.1e-08 34.1 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH42127.1 - 1e-05 24.5 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SelP_N PF04592.14 KFH42127.1 - 0.066 12.6 14.5 0.099 12.0 14.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ECH_1 PF00378.20 KFH42128.1 - 2.4e-53 181.0 0.0 4.2e-53 180.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH42128.1 - 2.9e-25 89.5 0.2 5.5e-21 75.4 0.3 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase WD40 PF00400.32 KFH42129.1 - 1.1e-08 35.6 2.5 0.09 13.7 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KFH42129.1 - 0.046 13.3 0.2 0.15 11.6 0.2 1.9 1 1 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KFH42129.1 - 0.16 12.3 0.2 2.3 8.6 0.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFH42129.1 - 0.47 11.0 2.1 1.1 9.8 0.1 2.7 3 1 0 3 3 3 0 PQQ-like domain Goodbye PF17109.5 KFH42130.1 - 6.2e-31 107.4 0.0 2.7e-30 105.3 0.0 2.2 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain TPR_1 PF00515.28 KFH42130.1 - 2e-11 43.2 3.8 0.0001 22.0 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH42130.1 - 2.7e-09 36.4 11.6 0.00055 19.8 0.1 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFH42130.1 - 6.1e-06 26.4 25.8 0.0044 17.3 0.4 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH42130.1 - 6.7e-06 25.9 7.2 0.082 13.2 0.0 5.5 7 0 0 7 7 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH42130.1 - 0.00016 22.1 0.3 0.00016 22.1 0.3 5.4 5 1 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH42130.1 - 0.0002 21.5 17.1 0.00063 19.9 1.1 4.7 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFH42130.1 - 0.00065 19.5 4.9 1.9 8.7 0.0 5.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH42130.1 - 0.0008 20.0 0.1 0.0008 20.0 0.1 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFH42130.1 - 0.017 15.8 10.0 3.7 8.4 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFH42130.1 - 0.018 14.7 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 KFH42130.1 - 0.02 15.7 17.8 0.031 15.1 0.0 7.2 7 1 1 8 8 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFH42130.1 - 0.028 14.8 0.0 0.16 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain DpnII-MboI PF18742.1 KFH42130.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 REase_DpnII-MboI NACHT PF05729.12 KFH42130.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TPR_17 PF13431.6 KFH42130.1 - 0.17 12.3 4.0 0.9 10.1 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFH42130.1 - 0.38 11.1 2.1 8.3 6.8 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFH42130.1 - 0.54 10.3 5.3 1.3 9.1 0.2 3.2 4 0 0 4 4 3 0 Putative TPR-like repeat CC2-LZ PF16516.5 KFH42130.1 - 0.83 10.1 0.0 0.83 10.1 0.0 3.7 5 0 0 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FYVE PF01363.21 KFH42130.1 - 1.2 9.4 5.3 2.9 8.1 5.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger TPR_10 PF13374.6 KFH42130.1 - 3.8 7.5 5.2 1.3e+02 2.6 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_hydro_71 PF03659.14 KFH42132.1 - 1.2e-124 416.0 0.8 1.3e-124 415.8 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Metallophos PF00149.28 KFH42133.1 - 8.7e-09 36.2 4.8 8.7e-09 36.2 4.8 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KFH42133.1 - 0.00061 20.0 0.0 0.0029 17.8 0.0 2.0 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain Alpha-amylase PF00128.24 KFH42134.1 - 2.2e-57 195.2 0.3 1.2e-55 189.4 0.3 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KFH42134.1 - 0.0054 15.0 0.1 0.027 12.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 hDGE_amylase PF14701.6 KFH42134.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_65N PF03636.15 KFH42134.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain GHL6 PF14871.6 KFH42134.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DUF871 PF05913.11 KFH42134.1 - 0.21 10.8 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) SLC35F PF06027.12 KFH42135.1 - 4e-101 338.5 18.5 5.1e-101 338.1 18.5 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KFH42135.1 - 3.5e-11 42.6 2.3 6e-11 41.9 2.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KFH42135.1 - 4.8e-07 30.0 30.3 0.00092 19.4 11.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Ctr PF04145.15 KFH42136.1 - 7.6e-38 130.4 0.9 9e-38 130.2 0.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.6 KFH42136.1 - 8.7 6.4 8.9 1.3e+02 2.6 8.9 2.1 1 1 0 1 1 1 0 Putative sensor GDE_C PF06202.14 KFH42137.1 - 0.021 13.8 0.0 0.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase 2OG-FeII_Oxy_3 PF13640.6 KFH42138.1 - 0.13 13.1 0.0 0.23 12.4 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_S9 PF00326.21 KFH42139.1 - 0.00026 20.5 0.6 0.0077 15.7 0.9 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFH42139.1 - 0.0013 18.2 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 KFH42139.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Amino_oxidase PF01593.24 KFH42140.1 - 5.9e-50 170.9 0.0 7.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH42140.1 - 2.1e-10 40.7 2.2 2.1e-10 40.7 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH42140.1 - 6.2e-08 32.1 1.5 1.1e-07 31.3 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFH42140.1 - 1.6e-07 31.0 1.0 2.5e-07 30.4 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH42140.1 - 4.3e-07 29.0 0.3 1.3e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KFH42140.1 - 1.9e-06 27.7 2.3 1.4e-05 24.9 2.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH42140.1 - 7.4e-06 25.4 0.9 1e-05 24.9 0.3 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KFH42140.1 - 0.00013 21.3 0.7 0.0078 15.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFH42140.1 - 0.00027 20.1 0.9 0.00041 19.5 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFH42140.1 - 0.00049 19.4 0.3 0.0011 18.3 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH42140.1 - 0.00096 18.3 0.2 0.0019 17.3 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KFH42140.1 - 0.0015 17.8 0.2 0.0028 17.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFH42140.1 - 0.0055 17.2 0.1 0.013 16.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Complex1_LYR PF05347.15 KFH42141.1 - 8.7e-15 54.5 0.7 1.2e-14 54.1 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFH42141.1 - 0.012 16.4 0.1 0.012 16.3 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Abhydrolase_2 PF02230.16 KFH42142.1 - 4.5e-58 196.6 0.0 5.9e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFH42142.1 - 2.3e-07 30.3 2.3 0.0012 18.2 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH42142.1 - 2.7e-05 23.9 0.3 0.68 9.5 0.2 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFH42142.1 - 4.9e-05 23.3 0.2 0.068 13.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KFH42142.1 - 8.5e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFH42142.1 - 0.00014 22.5 0.4 0.00022 21.9 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFH42142.1 - 0.0021 17.8 0.0 0.01 15.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFH42142.1 - 0.021 14.3 1.6 0.21 11.1 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2920 PF11144.8 KFH42142.1 - 0.079 12.1 0.0 2.1 7.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) EMC1_C PF07774.13 KFH42143.1 - 4e-73 245.6 0.0 6.9e-73 244.9 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFH42143.1 - 2.5e-22 79.6 8.6 2e-18 66.9 1.6 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFH42143.1 - 5.9e-05 22.8 3.9 0.059 13.3 0.1 5.5 6 0 0 6 6 6 1 PQQ enzyme repeat AMP-binding PF00501.28 KFH42144.1 - 1.5e-70 237.9 0.0 1.9e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH42144.1 - 1.3e-14 54.9 1.4 3e-14 53.7 0.6 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro_71 PF03659.14 KFH42146.1 - 7.4e-128 426.5 1.4 9.9e-128 426.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KFH42146.1 - 0.061 13.3 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF5519 PF17648.1 KFH42147.1 - 0.069 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5519) PAP_assoc PF03828.19 KFH42148.1 - 1.8e-16 60.0 0.4 5.2e-16 58.6 0.4 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFH42148.1 - 1.9e-06 28.1 0.0 4.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ferric_reduct PF01794.19 KFH42149.1 - 2.1e-23 82.8 7.9 2.1e-23 82.8 7.9 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH42149.1 - 1e-14 55.0 0.0 1.4e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH42149.1 - 1.6e-10 41.0 0.0 3.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFH42149.1 - 6.2e-06 26.8 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GFA PF04828.14 KFH42150.1 - 8.4e-09 35.7 0.2 1e-08 35.4 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme 2-Hacid_dh_C PF02826.19 KFH42151.1 - 2.5e-38 131.2 0.0 2.7e-27 95.3 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH42151.1 - 0.049 13.3 0.0 0.096 12.3 0.0 1.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CFEM PF05730.11 KFH42152.1 - 9.4e-12 44.9 11.2 1.5e-11 44.2 11.2 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KFH42152.1 - 0.036 14.3 1.1 0.091 13.0 1.1 1.6 1 0 0 1 1 1 0 Gamma-thionin family Phage_holin_2_2 PF10746.9 KFH42152.1 - 2.9 7.6 8.9 1.4 8.6 0.7 3.3 2 1 1 3 3 3 0 Phage holin T7 family, holin superfamily II AtuA PF07287.11 KFH42153.1 - 4.3e-129 430.2 0.0 5.2e-129 430.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA LYTB PF02401.18 KFH42153.1 - 5.7e-05 22.5 0.0 0.00014 21.3 0.0 1.6 2 0 0 2 2 2 1 LytB protein Zn_clus PF00172.18 KFH42154.1 - 0.00019 21.5 7.6 0.00019 21.5 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KFH42155.1 - 9.5e-74 248.5 0.1 1.3e-73 248.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH42155.1 - 5.1e-08 33.8 0.1 1.2e-07 32.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 KFH42155.1 - 0.015 15.6 0.2 0.31 11.3 0.1 2.6 2 0 0 2 2 2 0 FeoA domain DUF2985 PF11204.8 KFH42155.1 - 0.1 12.8 0.9 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) SdpI PF13630.6 KFH42155.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.5 3 1 1 4 4 4 0 SdpI/YhfL protein family Mpv17_PMP22 PF04117.12 KFH42156.1 - 2.2e-14 53.4 0.4 6e-14 52.0 0.3 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KFH42156.1 - 0.0085 16.3 1.1 0.036 14.3 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2530) BCS1_N PF08740.11 KFH42157.1 - 1.1e-32 113.6 0.8 1.1e-32 113.6 0.8 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KFH42157.1 - 1.5e-23 83.7 0.0 2.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH42157.1 - 2.5e-05 24.1 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KFH42157.1 - 0.03 13.5 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KFH42157.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFH42157.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1869 PF08956.10 KFH42157.1 - 0.13 12.1 0.0 11 6.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1869) IstB_IS21 PF01695.17 KFH42157.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFH42157.1 - 0.16 11.9 0.0 0.45 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFH42157.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 KFH42157.1 - 0.21 12.0 0.1 6.7 7.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KFH42157.1 - 0.22 11.9 0.0 0.54 10.7 0.0 1.7 2 0 0 2 2 2 0 RNA helicase ABC2_membrane PF01061.24 KFH42158.1 - 3e-81 271.9 58.5 4.4e-43 147.1 20.3 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KFH42158.1 - 1.7e-34 117.6 9.2 7.3e-29 99.5 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KFH42158.1 - 4.4e-32 111.4 0.0 1.8e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFH42158.1 - 1.4e-13 50.7 36.5 8.4e-10 38.3 10.2 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KFH42158.1 - 7.1e-13 49.0 0.0 2.6e-12 47.2 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFH42158.1 - 3.5e-07 30.7 0.2 0.0001 22.7 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFH42158.1 - 4.6e-06 26.7 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFH42158.1 - 2.7e-05 23.8 0.0 0.0075 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFH42158.1 - 3.8e-05 23.7 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFH42158.1 - 0.00028 20.6 0.0 0.0064 16.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFH42158.1 - 0.00059 20.4 0.0 0.0057 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFH42158.1 - 0.00073 19.5 0.2 0.031 14.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFH42158.1 - 0.00093 19.5 0.2 0.085 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFH42158.1 - 0.0016 18.5 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFH42158.1 - 0.0018 18.6 1.1 0.0047 17.2 0.2 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFH42158.1 - 0.0025 17.4 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFH42158.1 - 0.0068 16.8 0.2 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KFH42158.1 - 0.0071 16.9 0.1 0.063 13.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH42158.1 - 0.0078 16.4 0.0 0.33 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH42158.1 - 0.0078 16.0 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KFH42158.1 - 0.0093 15.8 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase TsaE PF02367.17 KFH42158.1 - 0.026 14.5 0.1 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KFH42158.1 - 0.026 13.6 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein SMC_N PF02463.19 KFH42158.1 - 0.052 13.0 0.0 7.8 5.9 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KFH42158.1 - 0.068 12.9 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFH42158.1 - 0.098 13.0 0.1 14 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KFH42158.1 - 0.11 12.9 2.0 0.38 11.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain Pantoate_ligase PF02569.15 KFH42158.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase FtsK_SpoIIIE PF01580.18 KFH42158.1 - 0.14 11.5 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ADH_N PF08240.12 KFH42159.1 - 6.8e-29 99.9 0.1 1.1e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH42159.1 - 1.3e-14 54.3 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFH42159.1 - 0.00017 21.4 0.4 0.00035 20.4 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KFH42159.1 - 0.0085 17.1 0.0 0.014 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CVNH PF08881.10 KFH42160.1 - 1.2e-12 48.3 0.3 2.3e-12 47.5 0.3 1.5 1 0 0 1 1 1 1 CVNH domain Glyco_hydro_75 PF07335.11 KFH42161.1 - 8.7e-57 191.9 0.6 1.1e-56 191.6 0.6 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 RhlB PF12300.8 KFH42162.1 - 0.00098 19.3 10.9 0.0017 18.5 10.9 1.3 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB TetR_C_11 PF16859.5 KFH42162.1 - 0.11 12.9 3.2 12 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain His_Phos_1 PF00300.22 KFH42164.1 - 4.1e-28 98.4 2.6 2.8e-27 95.7 2.6 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 KFH42165.1 - 4.1e-27 94.9 0.1 4.9e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH42165.1 - 8.8e-19 68.0 0.2 1.4e-18 67.3 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH42165.1 - 5.7e-08 32.9 0.3 1.1e-07 31.9 0.2 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFH42165.1 - 0.021 14.3 0.2 0.035 13.6 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFH42165.1 - 0.022 13.9 0.1 0.034 13.3 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1415 PF07209.12 KFH42165.1 - 0.21 11.3 0.3 0.76 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Abhydrolase_2 PF02230.16 KFH42166.1 - 5.2e-31 108.1 0.0 1.2e-23 84.1 0.0 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFH42166.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFH42166.1 - 0.019 15.6 0.2 0.044 14.4 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KFH42166.1 - 0.044 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFH42166.1 - 0.24 10.6 0.0 0.85 8.8 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipoxygenase PF00305.19 KFH42167.1 - 9.6e-20 70.6 0.1 1.5e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase HP0268 PF18618.1 KFH42167.1 - 0.18 12.3 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 HP0268 DUF3659 PF12396.8 KFH42168.1 - 1e-114 374.4 65.7 2.7e-23 81.7 4.7 6.7 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) CorA PF01544.18 KFH42168.1 - 0.076 12.3 0.4 0.12 11.7 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GCV_T_C PF08669.11 KFH42168.1 - 0.53 10.2 7.5 6.8 6.7 0.1 5.1 6 0 0 6 6 6 0 Glycine cleavage T-protein C-terminal barrel domain GWT1 PF06423.12 KFH42169.1 - 0.15 12.2 0.1 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 GWT1 BUD22 PF09073.10 KFH42170.1 - 0.45 9.8 42.9 0.52 9.6 42.9 1.1 1 0 0 1 1 1 0 BUD22 MCPVI PF02993.14 KFH42171.1 - 0.036 13.9 0.8 0.046 13.6 0.6 1.3 1 1 0 1 1 1 0 Minor capsid protein VI UPF0239 PF06783.11 KFH42171.1 - 3.7 7.8 7.2 5.7 7.2 7.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) AMP-binding PF00501.28 KFH42173.1 - 1.2e-95 320.6 0.1 1.6e-95 320.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH42173.1 - 4.7e-16 59.5 0.5 1.4e-15 58.0 0.5 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Esterase_phd PF10503.9 KFH42174.1 - 1.7e-20 73.5 0.2 2.4e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFH42174.1 - 3.9e-08 33.0 0.0 3.9e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KFH42174.1 - 0.043 12.7 0.1 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH42174.1 - 0.054 13.4 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_N_2 PF16884.5 KFH42175.1 - 1e-19 70.4 0.5 1.5e-19 69.9 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFH42175.1 - 2.2e-18 66.5 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH42175.1 - 5.7e-06 27.4 0.0 1.1e-05 26.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3113 PF11310.8 KFH42175.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Kinesin PF00225.23 KFH42176.1 - 1.3e-90 303.7 0.0 1.3e-90 303.7 0.0 3.3 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KFH42176.1 - 1.5e-16 60.6 0.0 9.3e-14 51.6 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding SNCAIP_SNCA_bd PF16700.5 KFH42176.1 - 0.16 11.7 1.3 23 4.8 0.1 3.1 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Pox_A_type_inc PF04508.12 KFH42176.1 - 1.3 9.0 4.2 12 5.9 0.0 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat 2OG-FeII_Oxy_2 PF13532.6 KFH42177.1 - 1.6e-14 54.6 0.0 2.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFH42177.1 - 0.0021 18.5 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ERCC4 PF02732.15 KFH42178.1 - 8.3e-19 68.3 0.0 1.6e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF5427 PF10310.9 KFH42178.1 - 0.49 9.3 10.2 0.75 8.7 10.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Herpes_DNAp_acc PF04929.12 KFH42178.1 - 0.7 8.8 8.2 1.1 8.2 8.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.12 KFH42178.1 - 2.4 7.9 6.8 3.7 7.3 6.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SIR4_SID PF16991.5 KFH42178.1 - 5.6 7.0 6.8 7 6.7 5.7 1.7 1 1 0 1 1 1 0 Sir4 SID domain Zn_clus PF00172.18 KFH42179.1 - 4e-06 26.8 12.4 6.9e-06 26.1 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Piwi PF02171.17 KFH42180.1 - 6.7e-72 242.3 0.0 9.7e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFH42180.1 - 1.2e-19 71.2 0.0 2.5e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFH42180.1 - 1.7e-14 53.2 0.1 3.6e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFH42180.1 - 2.7e-12 46.8 0.0 7e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KFH42180.1 - 6.2e-12 45.5 0.0 2.5e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 PAZ domain DUF3659 PF12396.8 KFH42182.1 - 1.3e-18 66.7 5.3 1.9e-13 50.1 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) G-patch PF01585.23 KFH42183.1 - 5.3e-05 23.0 0.1 9.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 G-patch domain zf-Di19 PF05605.12 KFH42183.1 - 0.03 14.6 0.5 0.055 13.8 0.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NIPSNAP PF07978.13 KFH42184.1 - 4.9e-39 132.7 6.8 4.2e-30 104.0 0.2 2.8 3 0 0 3 3 3 2 NIPSNAP GST_N_2 PF13409.6 KFH42185.1 - 1.1e-23 83.2 0.0 3.1e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH42185.1 - 2.6e-15 56.2 0.0 6.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFH42185.1 - 0.00011 22.6 0.1 0.0052 17.2 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFH42185.1 - 0.00093 19.4 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH42185.1 - 0.012 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFH42185.1 - 0.018 15.6 0.0 0.03 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AJAP1_PANP_C PF15298.6 KFH42186.1 - 0.23 11.7 10.0 0.28 11.4 10.0 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 KFH42186.1 - 1.2 9.1 21.3 1.4 8.9 21.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP1 PF08601.10 KFH42186.1 - 3.1 7.4 7.6 3.5 7.3 7.6 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 FKBP_C PF00254.28 KFH42187.1 - 4.4e-14 52.6 0.1 5.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sec1 PF00995.23 KFH42190.1 - 6.8e-118 395.4 0.0 7.8e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MLANA PF14991.6 KFH42191.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein melan-A AA_permease PF00324.21 KFH42193.1 - 7.7e-122 407.3 44.4 9.6e-122 407.0 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH42193.1 - 1.3e-32 113.1 48.5 1.8e-32 112.7 48.5 1.1 1 0 0 1 1 1 1 Amino acid permease RRM_1 PF00076.22 KFH42194.1 - 7e-07 29.0 0.0 7.4e-05 22.5 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aa_trans PF01490.18 KFH42195.1 - 1.6e-87 293.9 15.8 2.3e-87 293.4 15.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 KFH42195.1 - 0.0052 16.8 0.7 0.0052 16.8 0.7 2.6 3 0 0 3 3 3 1 Alpha/beta-hydrolase family N-terminus YfhO PF09586.10 KFH42195.1 - 0.046 12.0 3.1 0.076 11.2 3.1 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SH3_1 PF00018.28 KFH42196.1 - 1.3e-09 37.5 0.7 1.4e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFH42196.1 - 2.8e-07 30.1 0.0 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFH42196.1 - 8.6e-06 25.5 0.4 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF2070 PF09843.9 KFH42196.1 - 1.4 7.1 9.3 2 6.6 9.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Exo5 PF09810.9 KFH42197.1 - 4.3e-134 447.7 0.0 5e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease FoP_duplication PF13865.6 KFH42197.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.2 4 0 0 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 ThiF PF00899.21 KFH42198.1 - 1.4e-109 365.2 0.0 2.4e-72 243.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFH42198.1 - 6.3e-92 308.0 3.8 1.7e-91 306.6 0.7 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFH42198.1 - 2.3e-29 101.4 0.3 2.7e-28 98.0 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFH42198.1 - 3.7e-24 84.7 1.3 8.5e-24 83.5 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KFH42198.1 - 8.6e-24 84.1 0.2 2.6e-23 82.5 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain UAE_UbL PF14732.6 KFH42198.1 - 0.16 12.5 0.1 0.52 10.9 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Rogdi_lz PF10259.9 KFH42200.1 - 2.8e-88 295.9 0.0 3.2e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF3669 PF12417.8 KFH42201.1 - 3.7e-07 30.3 0.0 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Zinc finger protein Lyase_1 PF00206.20 KFH42202.1 - 8.1e-87 291.5 0.0 1.1e-86 291.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KFH42202.1 - 1.1e-22 80.6 0.1 2.2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FSH1 PF03959.13 KFH42204.1 - 4.8e-60 202.8 0.0 6e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 KFH42204.1 - 0.01 15.4 0.0 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 PE-PPE domain Abhydrolase_1 PF00561.20 KFH42204.1 - 0.011 15.4 0.0 0.83 9.2 0.1 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH42204.1 - 0.076 12.3 0.4 0.29 10.3 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KFH42204.1 - 0.17 11.4 3.0 2 7.8 1.2 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase ATP-synt_J PF04911.12 KFH42205.1 - 2.6e-25 87.8 0.3 2.6e-25 87.8 0.3 1.6 2 0 0 2 2 2 1 ATP synthase j chain zf-MYND PF01753.18 KFH42206.1 - 2.8e-05 24.1 9.9 6.9e-05 22.8 9.9 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KFH42206.1 - 0.0014 18.7 4.3 0.003 17.6 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_92 PF07971.12 KFH42207.1 - 1.1e-139 466.4 1.3 1.3e-139 466.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFH42207.1 - 5.2e-62 209.8 0.6 1.1e-61 208.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain KxDL PF10241.9 KFH42208.1 - 0.00068 19.9 2.5 0.082 13.2 0.0 2.6 1 1 2 3 3 3 1 Uncharacterized conserved protein Filament PF00038.21 KFH42208.1 - 0.0012 18.6 12.5 0.0027 17.4 12.3 1.6 1 1 0 1 1 1 1 Intermediate filament protein AAA_13 PF13166.6 KFH42208.1 - 0.0064 15.2 3.6 0.0081 14.9 3.6 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 KFH42208.1 - 0.01 14.8 12.0 0.023 13.6 12.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KFH42208.1 - 0.011 15.9 3.8 0.011 15.9 3.8 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 KFH42208.1 - 0.017 14.7 2.9 0.02 14.4 2.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG5 PF10392.9 KFH42208.1 - 0.024 14.8 0.6 1.3 9.2 0.0 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 ORF6C PF10552.9 KFH42208.1 - 0.027 14.5 6.3 0.17 12.0 0.2 2.4 1 1 0 2 2 2 0 ORF6C domain Troponin PF00992.20 KFH42208.1 - 0.082 13.2 15.8 1.6 9.0 0.5 2.2 2 0 0 2 2 2 0 Troponin V_ATPase_I PF01496.19 KFH42208.1 - 0.083 10.8 8.6 0.031 12.2 6.1 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KFH42208.1 - 0.11 12.5 16.9 0.15 12.1 10.5 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FadA PF09403.10 KFH42208.1 - 0.16 12.5 13.4 1 9.9 2.0 3.3 2 1 1 3 3 3 0 Adhesion protein FadA Jnk-SapK_ap_N PF09744.9 KFH42208.1 - 0.16 12.2 18.2 0.39 10.9 10.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Tho2 PF11262.8 KFH42208.1 - 0.29 10.3 7.4 0.09 12.0 2.9 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF641 PF04859.12 KFH42208.1 - 0.31 11.4 10.0 0.063 13.6 3.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ER PF01133.17 KFH42208.1 - 0.35 10.9 2.8 0.71 9.9 2.8 1.5 1 0 0 1 1 1 0 Enhancer of rudimentary CdvA PF18822.1 KFH42208.1 - 0.4 10.5 11.1 2 8.3 0.3 3.0 2 1 1 3 3 3 0 CdvA-like coiled-coil domain PspB PF06667.12 KFH42208.1 - 0.45 10.6 0.2 0.45 10.6 0.2 3.3 4 1 0 4 4 3 0 Phage shock protein B Fungal_lectin_2 PF18647.1 KFH42208.1 - 0.64 10.5 3.9 0.44 11.0 1.5 2.0 2 1 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin SHE3 PF17078.5 KFH42208.1 - 0.74 9.5 11.7 2.6 7.7 11.7 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Sec34 PF04136.15 KFH42208.1 - 1 9.3 8.3 5.3 6.9 0.3 2.9 1 1 2 3 3 3 0 Sec34-like family DUF465 PF04325.13 KFH42208.1 - 1.6 8.9 10.2 1 9.5 0.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF465) BLOC1_2 PF10046.9 KFH42208.1 - 1.7 9.0 12.3 4.2 7.7 3.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.11 KFH42208.1 - 2 8.5 5.1 3.3 7.8 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) ABC_tran_CTD PF16326.5 KFH42208.1 - 2.9 8.2 17.0 3.1 8.1 0.3 3.7 4 0 0 4 4 4 0 ABC transporter C-terminal domain ADIP PF11559.8 KFH42208.1 - 3.2 7.8 10.4 17 5.5 4.6 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 KFH42208.1 - 4.9 5.7 8.8 2.1 6.8 5.4 1.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF16 PF01519.16 KFH42208.1 - 5.6 7.5 9.6 14 6.2 4.8 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 THOC7 PF05615.13 KFH42208.1 - 6.2 7.1 14.3 15 5.8 14.2 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Glyco_hydro_7 PF00840.20 KFH42209.1 - 1.8e-144 481.7 2.5 2.3e-144 481.4 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DASH_Spc19 PF08287.11 KFH42210.1 - 4e-42 143.8 9.5 1.2e-41 142.2 9.5 1.7 1 1 0 1 1 1 1 Spc19 Aldedh PF00171.22 KFH42211.1 - 2.1e-133 445.2 0.0 2.6e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFH42211.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KFH42211.1 - 0.056 12.9 0.0 9.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) KIX_2 PF16987.5 KFH42211.1 - 0.1 12.6 0.4 0.4 10.7 0.4 1.9 1 1 0 1 1 1 0 KIX domain PCI PF01399.27 KFH42212.1 - 6.3e-22 78.1 0.0 3.4e-21 75.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFH42212.1 - 1.5e-16 60.1 2.6 4.6e-16 58.6 2.6 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Cas_DxTHG PF09455.10 KFH42212.1 - 0.098 12.2 4.7 0.044 13.4 2.4 1.6 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family YjeF_N PF03853.15 KFH42213.1 - 2.3e-31 109.0 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus NMD3 PF04981.13 KFH42214.1 - 1.3e-73 247.5 0.9 2.2e-73 246.7 0.9 1.4 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.21 KFH42214.1 - 6.4 7.0 7.9 9.9 6.4 2.3 2.6 2 0 0 2 2 2 0 FYVE zinc finger Ribosomal_S16 PF00886.19 KFH42215.1 - 4.8e-24 84.2 0.4 8.9e-24 83.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S16 Methyltransf_25 PF13649.6 KFH42216.1 - 8.7e-15 55.2 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH42216.1 - 8.1e-10 39.2 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH42216.1 - 3.1e-06 27.8 0.0 5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH42216.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH42216.1 - 6.1e-05 22.9 0.0 7.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH42216.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KFH42216.1 - 0.0088 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFH42216.1 - 0.041 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CheR PF01739.18 KFH42216.1 - 0.052 13.0 0.0 0.26 10.7 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Dynactin_p22 PF07426.11 KFH42217.1 - 5.7e-11 42.6 0.0 2.7e-10 40.3 0.0 1.8 1 1 1 2 2 2 1 Dynactin subunit p22 CCDC-167 PF15188.6 KFH42217.1 - 0.1 13.0 2.1 1.9 8.9 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PPR_2 PF13041.6 KFH42218.1 - 2.5e-44 149.2 10.4 7.7e-09 35.6 0.0 13.7 12 3 4 16 16 16 7 PPR repeat family PPR PF01535.20 KFH42218.1 - 2e-29 99.7 24.0 0.00037 20.6 0.0 15.3 19 0 0 19 19 19 6 PPR repeat PPR_3 PF13812.6 KFH42218.1 - 4.4e-27 93.9 0.0 0.011 15.8 0.0 10.3 9 3 3 12 12 12 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFH42218.1 - 1.4e-24 85.5 0.4 3e-07 30.0 0.0 10.1 10 0 0 10 10 10 5 PPR repeat PPR_long PF17177.4 KFH42218.1 - 9.8e-17 61.0 4.6 1.1e-06 28.2 0.0 6.3 4 3 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KFH42218.1 - 0.00024 21.5 0.0 0.016 15.6 0.0 3.4 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 KFH42218.1 - 0.0029 17.5 0.4 0.11 12.3 0.1 3.3 2 1 1 3 3 3 1 Mitochondrial ATPase expression TPR_7 PF13176.6 KFH42218.1 - 0.024 14.6 0.4 3.1 8.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42218.1 - 0.046 14.6 5.7 52 5.1 0.0 7.7 11 0 0 11 11 11 0 Tetratricopeptide repeat Esterase_phd PF10503.9 KFH42219.1 - 1.6e-05 24.5 0.0 6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KFH42219.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH42219.1 - 0.023 14.0 0.0 0.35 10.1 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFH42219.1 - 0.1 12.4 0.1 0.4 10.5 0.0 1.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF382 PF04037.13 KFH42221.1 - 2.2e-59 199.2 0.6 2.2e-59 199.2 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KFH42221.1 - 6.5e-19 67.5 3.7 1.4e-18 66.5 3.7 1.6 1 0 0 1 1 1 1 PSP MPC PF03650.13 KFH42223.1 - 8.6e-36 122.4 0.0 1.1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KFH42223.1 - 0.026 14.5 0.2 0.035 14.1 0.2 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PAPA-1 PF04795.12 KFH42224.1 - 1.6e-29 102.5 5.6 1.6e-29 102.5 5.6 4.1 4 1 1 5 5 5 1 PAPA-1-like conserved region Arb2 PF09757.9 KFH42225.1 - 1.5e-85 286.5 4.5 2e-56 191.0 0.4 2.2 1 1 1 2 2 2 2 Arb2 domain Hist_deacetyl PF00850.19 KFH42225.1 - 2.8e-81 273.4 0.1 6.7e-81 272.1 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain DBR1 PF05011.13 KFH42226.1 - 3.5e-27 95.5 0.0 5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFH42226.1 - 1e-06 29.4 0.5 1.5e-06 28.8 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPT PF03151.16 KFH42227.1 - 2e-54 184.9 8.0 2.5e-54 184.6 8.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH42227.1 - 8.2e-12 45.5 24.3 1.2e-07 32.0 8.1 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFH42227.1 - 1e-06 28.2 12.2 3.7e-06 26.4 12.2 1.8 1 1 0 1 1 1 1 UAA transporter family Glyco_transf_20 PF00982.21 KFH42230.1 - 6e-150 500.0 0.0 8.2e-150 499.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFH42230.1 - 5.3e-72 241.7 0.0 9.3e-72 240.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Baculo_DNA_bind PF04786.12 KFH42230.1 - 0.00054 19.4 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 ssDNA binding protein F-box-like PF12937.7 KFH42233.1 - 3.1e-07 30.2 0.1 8.4e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH42233.1 - 0.00017 21.4 0.1 0.00049 19.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFH42233.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 F-box Ras PF00071.22 KFH42234.1 - 3.2e-63 212.2 0.2 3.9e-63 211.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH42234.1 - 2.6e-35 121.2 0.2 3.7e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42234.1 - 4.2e-13 49.1 0.1 5.4e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH42234.1 - 5e-08 33.0 0.1 7.6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH42234.1 - 0.00023 20.8 0.1 0.0014 18.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH42234.1 - 0.00024 21.0 0.2 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFH42234.1 - 0.00042 19.7 0.1 0.00062 19.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFH42234.1 - 0.0027 18.0 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFH42234.1 - 0.0067 16.5 0.1 0.019 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH42234.1 - 0.016 15.6 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFH42234.1 - 0.017 15.6 0.1 0.026 15.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KFH42234.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFH42234.1 - 0.023 14.1 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KFH42234.1 - 0.029 13.9 0.1 0.07 12.7 0.0 1.6 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFH42234.1 - 0.036 13.8 0.1 0.082 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain SpoIIID PF12116.8 KFH42234.1 - 0.055 13.6 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_21 PF13304.6 KFH42234.1 - 0.09 12.6 0.6 0.13 12.0 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MCM PF00493.23 KFH42234.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KFH42234.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Chromo PF00385.24 KFH42235.1 - 4.1e-07 29.8 0.1 1.2e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Epimerase PF01370.21 KFH42238.1 - 4e-17 62.5 0.0 5.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFH42238.1 - 2.6e-06 27.1 0.0 1.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KFH42238.1 - 1.6e-05 24.9 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFH42238.1 - 0.00044 19.7 0.0 0.019 14.4 0.0 2.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFH42238.1 - 0.0046 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KFH42238.1 - 0.0055 15.8 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFH42238.1 - 0.047 12.7 0.0 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rossmann-like PF10727.9 KFH42238.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain DUF3693 PF12472.8 KFH42239.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Phage related protein CFEM PF05730.11 KFH42240.1 - 7.4e-08 32.4 5.9 1.5e-07 31.4 5.9 1.5 1 0 0 1 1 1 1 CFEM domain VEFS-Box PF09733.9 KFH42241.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 KFH42241.1 - 0.0021 17.9 3.4 0.0045 16.9 3.4 1.6 1 0 0 1 1 1 1 PHD-finger MTHFR_C PF12225.8 KFH42241.1 - 0.48 10.1 4.0 1 9.1 4.0 1.5 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf-tcix PF14952.6 KFH42241.1 - 1.8 8.2 5.0 0.28 10.8 0.8 1.8 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding AA_permease_2 PF13520.6 KFH42242.1 - 2.2e-71 240.9 37.5 2.7e-71 240.6 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH42242.1 - 3e-18 65.7 37.4 2.5e-17 62.6 37.4 2.0 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KFH42242.1 - 0.00077 18.3 12.2 0.0026 16.5 12.2 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pex14_N PF04695.13 KFH42243.1 - 3.2e-36 125.4 1.2 5.5e-36 124.6 1.2 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 KFH42244.1 - 1.4e-20 73.8 0.0 1.6e-09 37.6 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42244.1 - 2.4e-06 27.0 0.3 0.0001 21.7 0.0 3.1 3 1 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KFH42244.1 - 0.00018 21.5 0.6 0.0041 17.1 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH42244.1 - 0.19 11.0 0.0 0.48 9.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like ORC5_C PF14630.6 KFH42246.1 - 1.3e-83 280.9 0.0 1.6e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFH42246.1 - 2.6e-16 60.5 0.0 5.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFH42246.1 - 0.038 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFH42246.1 - 0.083 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-LITAF-like PF10601.9 KFH42247.1 - 4.5e-16 58.9 10.2 5.8e-16 58.5 10.2 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 KFH42247.1 - 0.00036 20.3 1.3 0.019 14.7 0.3 2.2 2 0 0 2 2 2 2 Cysteine-rich KTR Sgf11 PF08209.11 KFH42247.1 - 0.19 11.3 1.7 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_clus PF00172.18 KFH42248.1 - 5.6e-09 36.0 9.6 8.7e-09 35.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH42248.1 - 0.00011 21.3 0.1 0.00033 19.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRP14 PF15459.6 KFH42248.1 - 0.17 12.5 4.0 0.19 12.4 0.2 2.5 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 TFIIA PF03153.13 KFH42248.1 - 0.63 10.0 15.2 0.052 13.5 9.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Haem_oxygenas_2 PF14518.6 KFH42249.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Iron-containing redox enzyme Sugar_tr PF00083.24 KFH42250.1 - 8.5e-132 440.2 30.8 9.7e-132 440.0 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42250.1 - 1.5e-21 76.7 37.9 2.5e-14 53.0 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.20 KFH42250.1 - 0.16 11.0 4.9 0.33 9.9 4.8 1.5 1 1 0 1 1 1 0 Phosphate transporter family Herpes_LMP1 PF05297.11 KFH42250.1 - 3.9 6.6 4.6 8.3 5.5 4.6 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Brix PF04427.18 KFH42251.1 - 1.2e-38 133.2 0.0 1.7e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain EMP70 PF02990.16 KFH42252.1 - 0.092 11.4 3.5 0.11 11.1 3.5 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 PRIMA1 PF16101.5 KFH42252.1 - 0.1 12.6 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FleQ PF06490.11 KFH42254.1 - 0.04 14.3 0.0 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ DUF4588 PF15251.6 KFH42254.1 - 0.12 12.1 2.7 0.22 11.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4588) BUD22 PF09073.10 KFH42254.1 - 4.7 6.4 12.4 6.8 5.9 12.4 1.1 1 0 0 1 1 1 0 BUD22 GTP_EFTU PF00009.27 KFH42255.1 - 6.2e-48 162.9 0.0 1.1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KFH42255.1 - 5.1e-22 78.0 0.9 1.1e-21 76.9 0.9 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KFH42255.1 - 2.3e-10 40.7 0.0 8.1e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFH42255.1 - 8.2e-08 32.3 0.0 1.4e-06 28.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KFH42255.1 - 8.2e-08 32.5 0.3 3.9e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 KFH42255.1 - 0.0017 18.5 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFH42255.1 - 0.0065 16.1 0.1 0.36 10.4 0.0 2.5 1 1 1 2 2 2 1 Ras family Arf PF00025.21 KFH42255.1 - 0.027 13.9 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Septin PF00735.18 KFH42255.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin GTP_EFTU_D4 PF14578.6 KFH42255.1 - 0.029 14.3 1.2 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 SRPRB PF09439.10 KFH42255.1 - 0.035 13.5 0.0 1.8 8.0 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFH42255.1 - 0.14 11.7 0.1 2.3 7.7 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B TLP-20 PF06088.11 KFH42255.1 - 6.9 6.5 5.7 29 4.5 2.4 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Putative_PNPOx PF01243.20 KFH42256.1 - 9.6e-09 35.3 0.0 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase CTP_transf_like PF01467.26 KFH42257.1 - 7.4e-28 97.5 0.0 9.8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Cpn60_TCP1 PF00118.24 KFH42258.1 - 3.4e-159 530.6 3.9 3.8e-159 530.4 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ArfGap PF01412.18 KFH42261.1 - 7.1e-39 132.5 0.5 1.4e-38 131.5 0.5 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KFH42261.1 - 8.4e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Haem_bd PF14376.6 KFH42261.1 - 0.1 12.5 0.2 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 Haem-binding domain GATA PF00320.27 KFH42261.1 - 0.62 9.7 2.4 1.3 8.7 2.4 1.6 1 0 0 1 1 1 0 GATA zinc finger Glyco_hydro_72 PF03198.14 KFH42262.1 - 2.7e-124 414.5 0.6 3.3e-124 414.2 0.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFH42262.1 - 3.1e-05 23.6 0.2 0.00048 19.6 0.2 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tfb5 PF06331.12 KFH42264.1 - 1.8e-26 91.9 0.3 1.9e-26 91.8 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF2461 PF09365.10 KFH42266.1 - 1.3e-69 234.4 1.7 1.3e-69 234.4 1.7 2.2 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) HSP70 PF00012.20 KFH42267.1 - 3.6e-265 880.8 12.8 4.2e-265 880.6 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFH42267.1 - 1.5e-18 66.7 1.4 1.5e-16 60.1 0.5 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 KFH42267.1 - 0.016 14.5 0.9 0.76 9.0 0.1 2.8 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DDR PF08841.10 KFH42267.1 - 0.018 14.1 0.1 0.25 10.3 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 KFH42267.1 - 0.02 14.2 1.5 0.18 11.0 0.1 2.6 2 1 0 2 2 2 0 StbA protein FtsA PF14450.6 KFH42267.1 - 0.074 13.5 6.6 1.5 9.3 0.1 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Ppx-GppA PF02541.16 KFH42267.1 - 0.18 11.2 1.5 0.3 10.5 0.1 1.9 2 0 0 2 2 2 0 Ppx/GppA phosphatase family KCH PF16944.5 KFH42268.1 - 1.1e-98 330.0 6.5 1.3e-98 329.8 6.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel ECH_1 PF00378.20 KFH42269.1 - 1.4e-41 142.5 0.0 2.8e-41 141.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH42269.1 - 7.8e-30 104.5 0.0 2.3e-26 93.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Exo_endo_phos PF03372.23 KFH42270.1 - 0.0016 18.0 0.0 0.0043 16.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 KFH42271.1 - 1.1e-10 40.9 55.4 7.1e-10 38.3 53.2 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TetR_C_14 PF17754.1 KFH42271.1 - 0.25 11.3 2.7 0.36 10.8 0.9 2.2 2 0 0 2 2 2 0 MftR C-terminal domain DUF2109 PF09882.9 KFH42271.1 - 1.8 8.6 7.2 2.4 8.2 3.1 2.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2109) RTA1 PF04479.13 KFH42272.1 - 5.3e-52 176.4 8.2 5.3e-52 176.4 8.2 1.3 1 1 0 1 1 1 1 RTA1 like protein zf-CHY PF05495.12 KFH42273.1 - 6e-10 39.5 11.0 6e-10 39.5 11.0 3.3 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 KFH42273.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain Mu-like_Com PF10122.9 KFH42273.1 - 0.021 14.3 0.5 0.11 12.0 0.0 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Phage_T7_Capsid PF05396.11 KFH42273.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein ATG16 PF08614.11 KFH42273.1 - 0.35 11.1 2.4 0.84 9.8 2.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3295 PF11702.8 KFH42274.1 - 8.4e-147 490.5 34.9 1.2e-146 489.9 34.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KFH42274.1 - 6.1e-13 48.3 0.9 1.1e-12 47.5 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_transf_90 PF05686.12 KFH42275.1 - 5.8e-18 65.0 0.0 3.1e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Oxysterol_BP PF01237.18 KFH42276.1 - 3.2e-108 361.9 0.0 5.9e-108 361.0 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KFH42276.1 - 1.2e-37 128.1 0.4 4.4e-37 126.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFH42276.1 - 3.3e-07 30.8 0.1 9.7e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 KFH42276.1 - 0.063 13.0 0.4 0.3 10.9 0.3 2.1 2 0 0 2 2 2 0 PH domain TMEM154 PF15102.6 KFH42278.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KFH42278.1 - 0.038 14.9 0.0 0.055 14.4 0.0 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KFH42278.1 - 0.062 13.9 0.0 0.09 13.4 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 KFH42278.1 - 2.7 7.5 6.6 4.1 6.9 6.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATP-synt_ab PF00006.25 KFH42279.1 - 5.2e-73 245.2 0.0 7.7e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFH42279.1 - 6.5e-47 159.0 0.1 1.1e-46 158.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFH42279.1 - 2.6e-11 43.9 0.8 7.2e-11 42.5 0.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RNase_PH PF01138.21 KFH42281.1 - 3.9e-13 50.0 0.1 8.7e-13 48.9 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFH42281.1 - 0.002 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PITH PF06201.13 KFH42282.1 - 4.1e-36 124.5 0.0 5.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFH42282.1 - 1.3e-27 95.7 0.0 2.1e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFH42282.1 - 5.2e-07 30.1 0.0 2e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFH42282.1 - 7.8e-06 26.1 0.0 5.5e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFH42282.1 - 3.8e-05 23.2 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFH42282.1 - 0.00063 19.5 0.1 0.0073 16.0 0.0 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KFH42282.1 - 0.0037 17.2 0.0 0.024 14.6 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KFH42282.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 KFH42282.1 - 0.044 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DJ-1_PfpI PF01965.24 KFH42283.1 - 2.9e-11 43.4 0.0 3.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 KFH42284.1 - 0.0013 17.8 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42284.1 - 0.0017 18.5 12.4 0.0031 17.6 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KFH42284.1 - 0.017 15.1 3.0 0.028 14.5 0.4 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WLM PF08325.10 KFH42286.1 - 1.2e-28 100.5 0.4 4.8e-28 98.5 0.4 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KFH42286.1 - 7.2e-07 29.5 1.1 7.2e-07 29.5 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 NINJA_B PF16136.5 KFH42286.1 - 6.6 7.1 8.1 21 5.5 8.1 1.8 1 0 0 1 1 1 0 Putative nuclear localisation signal BTB PF00651.31 KFH42287.1 - 1e-07 32.2 0.0 2.9e-07 30.7 0.0 1.6 1 1 1 2 2 2 1 BTB/POZ domain Homeodomain PF00046.29 KFH42288.1 - 8.1e-14 51.2 5.3 1.6e-13 50.3 5.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFH42288.1 - 0.091 12.7 0.7 0.29 11.1 0.7 1.8 1 0 0 1 1 1 0 Homeobox KN domain RepB-RCR_reg PF10723.9 KFH42288.1 - 0.21 11.6 0.4 17 5.4 0.0 2.6 2 1 0 2 2 2 0 Replication regulatory protein RepB EF-1_beta_acid PF10587.9 KFH42288.1 - 0.22 12.0 3.5 0.5 10.9 3.5 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pkinase PF00069.25 KFH42289.1 - 4.2e-23 82.1 0.7 1.1e-18 67.6 0.1 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42289.1 - 3.2e-09 36.5 0.0 7.6e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFH42289.1 - 0.0028 17.6 0.3 0.007 16.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH42289.1 - 0.029 13.3 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFH42289.1 - 0.058 12.4 0.1 0.096 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KFH42289.1 - 0.074 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Exo_endo_phos PF03372.23 KFH42290.1 - 1.1e-17 64.3 1.5 1.9e-17 63.5 1.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nas2_N PF18265.1 KFH42291.1 - 3.4e-29 100.6 0.1 4.6e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KFH42291.1 - 8.8e-07 28.7 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFH42291.1 - 1.4e-06 28.5 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFH42291.1 - 5.7e-06 26.7 0.0 9.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KFH42291.1 - 0.00059 20.1 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain tRNA-synt_2 PF00152.20 KFH42292.1 - 9.8e-68 228.5 0.0 1.3e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Fungal_trans_2 PF11951.8 KFH42293.1 - 0.00015 20.7 0.1 0.0017 17.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain GOLGA2L5 PF15070.6 KFH42294.1 - 0.0049 15.6 0.4 0.0049 15.6 0.4 1.6 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 DUF3450 PF11932.8 KFH42294.1 - 0.043 13.1 5.4 0.051 12.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-K PF11802.8 KFH42295.1 - 1e-05 25.3 10.9 0.0032 17.1 7.5 2.9 2 2 0 2 2 2 2 Centromere-associated protein K BST2 PF16716.5 KFH42295.1 - 0.87 10.2 15.0 0.13 12.8 2.5 3.6 4 0 0 4 4 4 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 KFH42295.1 - 2.4 7.2 9.3 5.8 5.9 9.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IMD PF08397.11 KFH42295.1 - 3.1 7.1 8.3 0.24 10.7 2.0 2.2 3 0 0 3 3 3 0 IRSp53/MIM homology domain SlyX PF04102.12 KFH42295.1 - 9.2 7.0 8.8 17 6.1 0.1 3.7 3 1 0 3 3 3 0 SlyX Spectrin PF00435.21 KFH42295.1 - 9.5 6.8 10.6 0.9 10.1 0.6 3.2 3 1 0 3 3 3 0 Spectrin repeat RabGAP-TBC PF00566.18 KFH42296.1 - 1.2e-32 113.3 0.0 2.5e-32 112.3 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L5 PF00281.19 KFH42297.1 - 4.6e-20 71.7 0.1 1e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFH42297.1 - 5e-19 68.3 0.1 1.4e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Carb_kinase PF01256.17 KFH42298.1 - 3.5e-56 190.4 0.1 4.6e-56 190.0 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KFH42298.1 - 0.017 14.5 0.4 0.045 13.1 0.4 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PTPA PF03095.15 KFH42299.1 - 1.2e-108 363.2 0.0 1.3e-108 363.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_trans_2_3 PF13632.6 KFH42300.1 - 1.2e-17 64.5 0.8 1.2e-17 64.5 0.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 NAD_kinase PF01513.21 KFH42301.1 - 2e-78 263.6 0.0 2.6e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Clr5 PF14420.6 KFH42302.1 - 5.5e-19 68.1 3.1 1.1e-18 67.2 3.1 1.5 1 0 0 1 1 1 1 Clr5 domain UreE_N PF02814.15 KFH42302.1 - 0.068 12.8 0.2 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain TPR_12 PF13424.6 KFH42302.1 - 0.077 13.3 3.0 0.4 11.0 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42302.1 - 1.6 9.7 10.7 3.3 8.8 2.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat FmiP_Thoc5 PF09766.9 KFH42303.1 - 1.4e-31 110.1 15.1 2e-31 109.6 15.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF3958 PF13125.6 KFH42303.1 - 0.0016 18.6 12.5 0.012 15.7 9.8 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3958) SPATA1_C PF15743.5 KFH42303.1 - 0.031 14.3 3.2 0.031 14.3 3.2 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF641 PF04859.12 KFH42303.1 - 0.3 11.4 8.2 0.12 12.7 1.7 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TSC22 PF01166.18 KFH42303.1 - 0.39 11.1 4.8 0.56 10.6 0.3 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family FUSC PF04632.12 KFH42303.1 - 0.5 8.8 9.8 0.6 8.6 9.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.11 KFH42303.1 - 0.64 10.6 4.7 2.5 8.7 0.9 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KFH42303.1 - 0.94 9.5 4.0 11 6.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KFH42303.1 - 1.3 9.4 17.9 0.45 10.9 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Aldedh PF00171.22 KFH42303.1 - 9.3 4.6 7.4 0.96 7.9 1.4 1.9 1 1 1 2 2 2 0 Aldehyde dehydrogenase family Ras PF00071.22 KFH42305.1 - 2.5e-48 163.7 0.0 3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH42305.1 - 3.9e-29 101.3 0.0 9.8e-29 100.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42305.1 - 3e-10 39.8 0.0 3.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH42305.1 - 0.00035 20.6 0.0 0.00066 19.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFH42305.1 - 0.00062 20.1 0.1 0.0047 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KFH42305.1 - 0.0068 15.8 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFH42305.1 - 0.012 14.8 1.7 0.41 9.8 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 KFH42305.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KFH42305.1 - 0.021 14.3 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KFH42305.1 - 0.037 13.9 0.1 8.2 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KFH42305.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFH42305.1 - 0.085 12.9 0.1 0.18 11.8 0.1 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFH42305.1 - 0.1 12.7 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH42305.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 KFH42305.1 - 0.2 10.8 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.18 KFH42305.1 - 0.23 10.7 0.8 0.28 10.4 0.1 1.5 2 0 0 2 2 2 0 Septin Pkinase PF00069.25 KFH42306.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain YrbL-PhoP_reg PF10707.9 KFH42307.1 - 0.4 10.2 1.7 0.31 10.5 0.4 1.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL NPL PF17800.1 KFH42308.1 - 1.9e-34 118.4 0.1 1.9e-34 118.4 0.1 2.3 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KFH42308.1 - 7.1e-30 103.2 0.1 1.9e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PCNA_C PF02747.15 KFH42309.1 - 5.8e-51 172.0 0.1 2.7e-50 169.8 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KFH42309.1 - 9.7e-48 161.1 5.6 1.2e-47 160.8 3.8 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KFH42309.1 - 2.8e-08 33.5 0.1 3.6e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KFH42309.1 - 3.4e-06 26.3 0.2 9.9e-06 24.8 0.2 1.7 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DNA_pol3_beta_3 PF02768.15 KFH42309.1 - 0.032 14.1 0.2 0.16 11.8 0.1 2.2 2 2 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Hus1 PF04005.12 KFH42309.1 - 0.05 12.7 0.3 0.66 9.0 0.1 2.1 2 1 0 2 2 2 0 Hus1-like protein AMA-1 PF02430.15 KFH42309.1 - 0.06 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 PWI PF01480.17 KFH42310.1 - 6.1e-28 96.9 0.0 1e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 PWI domain RhoGAP PF00620.27 KFH42311.1 - 1.4e-41 141.9 0.2 2.2e-41 141.2 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFH42311.1 - 5.6e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFH42311.1 - 0.04 14.2 0.1 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 KFH42311.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PX domain KH_1 PF00013.29 KFH42312.1 - 1.7e-42 143.0 7.3 4.4e-18 64.9 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFH42312.1 - 1.2e-12 47.5 4.0 0.0031 17.3 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFH42312.1 - 2e-07 30.8 1.3 0.057 13.3 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KFH42312.1 - 4.5e-06 26.6 0.0 0.0014 18.6 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KFH42312.1 - 1.8e-05 24.7 5.0 0.39 10.8 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain Phos_pyr_kin PF08543.12 KFH42313.1 - 9.3e-12 44.8 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFH42313.1 - 9.7e-09 34.9 0.7 6.2e-08 32.3 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase DnaJ PF00226.31 KFH42314.1 - 3.1e-17 62.5 0.4 4.8e-17 61.8 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain LSM PF01423.22 KFH42315.1 - 3.1e-17 62.0 0.0 4.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain HlyIII PF03006.20 KFH42316.1 - 3.3e-57 193.8 16.8 4.1e-57 193.5 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF883 PF05957.13 KFH42316.1 - 0.0081 16.7 5.6 0.055 14.1 0.9 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF2894 PF11445.8 KFH42316.1 - 0.087 13.3 1.8 0.13 12.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) tRNA_int_endo PF01974.17 KFH42317.1 - 1.9e-12 47.1 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.21 KFH42318.1 - 8.2e-27 94.3 0.0 1.5e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_8 PF13450.6 KFH42319.1 - 5.4e-15 55.4 0.0 1.6e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFH42319.1 - 6.7e-07 28.9 0.0 3.4e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFH42319.1 - 9.3e-06 25.5 0.1 0.00028 20.6 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH42319.1 - 0.0015 17.8 0.0 0.0079 15.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH42319.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFH42319.1 - 0.038 14.0 0.1 0.56 10.2 0.0 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding PAXNEB PF05625.11 KFH42320.1 - 3.5e-102 342.3 0.0 4.1e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Sulfotransfer_4 PF17784.1 KFH42322.1 - 4.7e-48 163.9 0.0 5.5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH42322.1 - 0.00057 20.3 0.1 0.012 16.0 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family RRM_1 PF00076.22 KFH42323.1 - 4.5e-24 84.1 0.9 5.8e-12 45.3 0.3 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH42323.1 - 8e-06 25.5 0.0 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFH42323.1 - 0.0011 18.9 0.2 0.0032 17.3 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 KFH42323.1 - 0.0012 18.6 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Guanylate_cyc PF00211.20 KFH42323.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain RRM_3 PF08777.11 KFH42323.1 - 0.081 13.0 0.8 0.22 11.6 0.7 1.9 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 KFH42323.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Fungal_trans_2 PF11951.8 KFH42324.1 - 4.7e-10 38.8 3.2 6.4e-09 35.1 3.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42324.1 - 0.00065 19.8 2.7 0.0012 18.9 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_14 PF13428.6 KFH42325.1 - 2.7e-11 43.3 10.8 3.1 8.8 0.7 10.4 10 2 2 12 12 10 3 Tetratricopeptide repeat Suf PF05843.14 KFH42325.1 - 4.9e-09 36.6 9.0 0.038 14.0 1.8 5.7 4 1 2 6 6 6 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KFH42325.1 - 2.2e-07 30.9 6.6 0.3 11.1 0.1 6.9 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KFH42325.1 - 9e-07 29.1 0.9 3.7 7.9 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFH42325.1 - 1.3e-06 27.8 8.0 2.8e-05 23.5 1.3 4.6 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH42325.1 - 5.6e-06 26.2 2.3 3 8.3 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFH42325.1 - 0.00055 20.4 0.0 11 6.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFH42325.1 - 0.0018 18.2 11.5 1 9.6 0.0 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.9 KFH42325.1 - 0.016 14.9 0.1 0.15 11.7 0.1 2.6 3 1 0 3 3 3 0 26S proteasome subunit RPN7 MIT PF04212.18 KFH42325.1 - 0.13 12.4 0.3 0.73 9.9 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain HAT PF02184.16 KFH42325.1 - 1.7 8.7 17.7 7.5 6.6 2.2 6.9 6 1 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.6 KFH42325.1 - 2 8.4 8.7 1.2e+02 2.7 0.4 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat NPP1 PF05630.11 KFH42326.1 - 3e-50 171.1 0.2 3.9e-50 170.7 0.2 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Syja_N PF02383.18 KFH42327.1 - 8.7e-75 252.0 0.0 1.6e-74 251.1 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain PolyA_pol PF01743.20 KFH42328.1 - 5.3e-26 91.5 0.1 1.1e-25 90.6 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFH42328.1 - 0.03 14.1 0.1 0.085 12.6 0.1 1.8 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KFH42328.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative MFS_1 PF07690.16 KFH42329.1 - 2.3e-29 102.4 43.8 1.7e-24 86.5 23.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42329.1 - 6.1e-07 28.7 6.6 6.1e-07 28.7 6.6 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter DUF347 PF03988.12 KFH42329.1 - 0.17 12.1 0.1 0.17 12.1 0.1 4.4 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) zf-C3HC4_3 PF13920.6 KFH42330.1 - 2e-08 34.0 12.5 3.5e-08 33.2 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH42330.1 - 0.085 12.7 12.3 0.15 11.9 12.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PI3K_1B_p101 PF10486.9 KFH42330.1 - 0.18 9.5 0.2 0.55 7.9 0.1 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Anp1 PF03452.14 KFH42331.1 - 1.4e-113 378.7 0.2 8.4e-113 376.1 0.0 2.2 3 0 0 3 3 3 1 Anp1 Glycos_transf_2 PF00535.26 KFH42331.1 - 0.023 14.5 0.0 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 Rad54_N PF08658.10 KFH42331.1 - 0.09 12.9 1.5 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Rad54 N terminal RNA_pol_Rpb8 PF03870.15 KFH42332.1 - 1.7e-46 157.9 0.0 1.9e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KFH42332.1 - 0.001 19.1 0.3 0.068 13.2 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF4743 PF15916.5 KFH42333.1 - 2.1e-13 50.3 0.0 3.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KFH42333.1 - 3.2e-12 46.6 0.6 8.3e-12 45.3 0.1 1.9 3 0 0 3 3 3 1 NUDIX domain ThiF PF00899.21 KFH42334.1 - 3.4e-21 75.7 0.0 9.5e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family Ldh_1_N PF00056.23 KFH42335.1 - 2e-27 96.0 0.1 2.9e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFH42335.1 - 2.9e-17 63.1 0.0 4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 KFH42335.1 - 0.029 14.0 0.2 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KFH42335.1 - 0.044 14.4 1.4 0.2 12.2 0.9 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KFH42335.1 - 0.072 12.4 0.4 0.23 10.8 0.3 1.8 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.14 KFH42335.1 - 0.13 11.8 3.3 0.89 9.1 3.3 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.18 KFH42336.1 - 1.2e-24 86.8 0.0 2.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42336.1 - 1.2e-07 31.8 12.9 2.1e-07 30.9 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.11 KFH42336.1 - 0.12 12.7 2.1 60 4.1 0.1 4.2 4 1 0 4 4 4 0 Aerotolerance regulator N-terminal AMP-binding PF00501.28 KFH42337.1 - 1.3e-63 215.1 0.0 1.9e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KFH42337.1 - 2.8e-12 46.8 0.0 6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KFH42337.1 - 9.9e-07 28.3 5.2 1.1 9.1 0.0 5.6 6 0 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 KFH42337.1 - 6.5e-06 27.0 0.2 0.05 14.6 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ATP-synt_D PF01813.17 KFH42338.1 - 5.4e-62 209.1 5.1 2.2e-56 190.8 0.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit D DUF5446 PF17522.2 KFH42338.1 - 0.21 11.8 2.5 1.1 9.5 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TT_ORF2 PF02957.15 KFH42338.1 - 0.36 11.8 3.0 0.64 10.9 3.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 DASH_Spc19 PF08287.11 KFH42338.1 - 5.6 6.8 11.5 6 6.7 9.2 2.2 2 1 0 2 2 2 0 Spc19 zf-RING_5 PF14634.6 KFH42339.1 - 3.6e-07 30.0 7.8 7.7e-07 29.0 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH42339.1 - 0.00085 19.1 3.9 0.0017 18.2 3.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFH42339.1 - 0.0013 18.6 6.7 0.0025 17.6 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH42339.1 - 0.0014 18.6 1.2 0.0014 18.6 1.2 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH42339.1 - 0.0015 18.8 7.6 0.0015 18.8 7.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFH42339.1 - 0.0075 16.1 7.0 0.015 15.1 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.14 KFH42339.1 - 0.011 16.1 5.0 0.016 15.5 5.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C3HC4_2 PF13923.6 KFH42339.1 - 0.016 15.1 5.9 0.1 12.4 6.2 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EzrA PF06160.12 KFH42339.1 - 0.018 13.2 6.1 0.024 12.8 6.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA EMP24_GP25L PF01105.24 KFH42339.1 - 0.028 14.3 1.7 0.046 13.7 1.7 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4201 PF13870.6 KFH42339.1 - 0.049 13.4 5.2 0.069 12.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KFH42339.1 - 0.058 12.3 3.7 0.08 11.8 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C3HC4_4 PF15227.6 KFH42339.1 - 0.059 13.5 2.2 0.15 12.3 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFH42339.1 - 0.067 13.0 2.6 0.16 11.8 2.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain STAT_alpha PF01017.20 KFH42339.1 - 0.093 12.6 2.3 0.14 12.1 2.3 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Osmo_CC PF08946.10 KFH42339.1 - 0.13 12.5 1.1 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Mito_carr PF00153.27 KFH42339.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein FapA PF03961.13 KFH42339.1 - 0.26 9.9 1.5 0.34 9.5 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PhnA_Zn_Ribbon PF08274.12 KFH42339.1 - 0.41 10.6 3.1 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF1272 PF06906.11 KFH42339.1 - 0.47 10.6 4.4 8.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KFH42339.1 - 1.2 9.4 5.8 2.7 8.3 5.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain NAD_binding_1 PF00175.21 KFH42339.1 - 1.4 9.6 3.1 6.6 7.4 0.3 2.2 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain DZR PF12773.7 KFH42339.1 - 2.2 8.4 6.4 5.3 7.2 6.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon Glyco_transf_15 PF01793.16 KFH42340.1 - 1.3e-98 330.3 1.3 2.1e-98 329.6 1.3 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_S10 PF00450.22 KFH42341.1 - 1.2e-56 192.9 0.0 1.5e-56 192.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF775 PF05603.12 KFH42343.1 - 7.5e-59 198.6 2.6 1.9e-58 197.3 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Sec7 PF01369.20 KFH42344.1 - 2.2e-62 210.0 0.0 4.6e-62 209.0 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFH42344.1 - 7.3e-16 58.5 0.0 2.5e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFH42344.1 - 0.021 14.5 0.0 0.09 12.4 0.0 2.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF913 PF06025.12 KFH42344.1 - 0.87 8.5 6.2 0.12 11.4 0.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Exotox-A_target PF09102.10 KFH42345.1 - 0.0055 16.7 0.0 2.3 8.2 0.0 2.4 2 1 0 2 2 2 2 Exotoxin A, targeting Methyltransf_25 PF13649.6 KFH42345.1 - 0.028 15.1 0.0 0.13 13.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Tti2 PF10521.9 KFH42346.1 - 8.1e-84 281.5 0.1 1.1e-83 281.0 0.1 1.2 1 0 0 1 1 1 1 Tti2 family HEAT PF02985.22 KFH42346.1 - 0.13 12.6 1.3 3.1 8.3 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat GFA PF04828.14 KFH42347.1 - 6.3e-06 26.4 5.5 0.03 14.7 0.2 2.7 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme RNA_pol_Rpb4 PF03874.16 KFH42348.1 - 1.2e-16 61.1 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.20 KFH42350.1 - 1.3e-31 109.2 0.0 1.5e-30 105.8 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase AAA PF00004.29 KFH42351.1 - 8e-52 175.2 0.0 2.9e-39 134.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH42351.1 - 1.2e-10 41.8 0.0 0.0003 21.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KFH42351.1 - 9.9e-10 38.1 0.4 2.6e-09 36.7 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KFH42351.1 - 3.4e-09 37.3 0.0 0.0057 17.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KFH42351.1 - 8.9e-08 32.0 0.2 0.0079 15.9 0.0 2.9 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFH42351.1 - 9.9e-08 31.6 0.0 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KFH42351.1 - 7e-07 29.3 0.0 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH42351.1 - 7e-07 29.5 0.0 0.00019 21.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFH42351.1 - 4.6e-06 26.8 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KFH42351.1 - 8.8e-06 25.8 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFH42351.1 - 1.5e-05 24.6 0.4 0.033 13.7 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFH42351.1 - 1.6e-05 24.4 0.2 0.005 16.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFH42351.1 - 2.1e-05 24.8 0.0 0.14 12.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.17 KFH42351.1 - 2.6e-05 23.9 0.1 0.0044 16.8 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 KFH42351.1 - 3.2e-05 23.9 0.1 4.2 7.2 0.0 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KFH42351.1 - 0.00028 20.6 0.0 0.69 9.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 KFH42351.1 - 0.00033 21.2 0.0 0.097 13.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KFH42351.1 - 0.00041 20.1 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFH42351.1 - 0.00043 20.2 1.4 0.57 10.1 0.1 3.6 3 1 0 3 3 2 1 NACHT domain TsaE PF02367.17 KFH42351.1 - 0.00063 19.7 0.0 0.69 9.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KFH42351.1 - 0.00067 19.4 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KFH42351.1 - 0.00071 19.0 0.1 0.018 14.4 0.1 2.4 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 KFH42351.1 - 0.0027 18.2 1.0 0.25 11.9 0.1 3.0 3 0 0 3 3 3 1 ABC transporter PhoH PF02562.16 KFH42351.1 - 0.0029 17.1 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 KFH42351.1 - 0.0052 15.9 0.2 1.3 8.1 0.0 2.7 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KFH42351.1 - 0.0075 15.5 0.3 2 7.6 0.2 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 KFH42351.1 - 0.0095 15.7 0.0 0.28 10.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KFH42351.1 - 0.01 15.7 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFH42351.1 - 0.022 14.3 1.3 4.1 6.9 0.0 2.8 4 0 0 4 4 2 0 AAA domain ResIII PF04851.15 KFH42351.1 - 0.028 14.4 0.1 13 5.7 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KFH42351.1 - 0.028 14.7 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFH42351.1 - 0.035 13.5 0.1 7.7 5.9 0.1 2.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 KFH42351.1 - 0.036 13.8 0.1 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFH42351.1 - 0.045 14.1 0.1 0.61 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.9 KFH42351.1 - 0.048 12.8 0.0 3 6.9 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SKA1 PF07160.12 KFH42352.1 - 0.00072 19.5 0.9 0.00081 19.3 0.9 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 SlyX PF04102.12 KFH42352.1 - 0.0019 18.7 1.3 0.0019 18.7 1.3 1.9 2 1 0 2 2 2 1 SlyX Alpha-2-MRAP_C PF06401.11 KFH42352.1 - 0.0035 17.3 0.7 0.0051 16.8 0.7 1.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain DUF4600 PF15372.6 KFH42352.1 - 0.0086 16.5 0.4 0.013 16.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) KLRAQ PF10205.9 KFH42352.1 - 0.0094 16.2 2.8 0.014 15.6 2.8 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein EzrA PF06160.12 KFH42352.1 - 0.0095 14.2 0.7 0.012 13.8 0.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA ATG16 PF08614.11 KFH42352.1 - 0.016 15.5 5.2 0.016 15.5 5.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KFH42352.1 - 0.02 14.9 3.0 0.043 13.8 3.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding COG5 PF10392.9 KFH42352.1 - 0.021 15.0 0.7 0.031 14.5 0.7 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DegS PF05384.11 KFH42352.1 - 0.022 14.2 3.3 0.03 13.8 3.3 1.1 1 0 0 1 1 1 0 Sensor protein DegS Sugarporin_N PF11471.8 KFH42352.1 - 0.023 14.7 2.9 0.023 14.7 2.9 2.1 2 1 1 3 3 2 0 Maltoporin periplasmic N-terminal extension Seryl_tRNA_N PF02403.22 KFH42352.1 - 0.024 14.9 2.5 0.033 14.4 2.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KFH42352.1 - 0.049 12.5 2.7 0.059 12.2 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DGF-1_C PF11040.8 KFH42352.1 - 0.066 13.2 2.1 11 6.2 0.5 2.5 1 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus XhlA PF10779.9 KFH42352.1 - 0.07 13.3 1.8 0.12 12.6 1.8 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 KFH42352.1 - 0.098 12.7 0.9 0.17 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 KFH42352.1 - 0.15 11.6 1.0 0.18 11.3 1.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Atg14 PF10186.9 KFH42352.1 - 0.18 10.9 2.6 0.19 10.8 2.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KFH42352.1 - 0.23 10.8 2.5 0.27 10.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 KFH42352.1 - 0.24 10.7 5.7 0.19 11.0 4.4 1.5 1 1 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 KFH42352.1 - 0.28 9.0 1.8 0.3 8.9 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KFH42352.1 - 0.3 10.3 1.7 0.37 10.0 1.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 KFH42352.1 - 0.36 11.1 4.6 0.66 10.3 3.2 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 KFH42352.1 - 2 8.7 5.5 3.5 7.9 5.4 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Ribosomal_S2 PF00318.20 KFH42353.1 - 9.4e-25 87.1 0.1 3.1e-14 52.7 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KFH42353.1 - 0.00013 23.3 15.8 0.00024 22.4 15.8 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus COX14 PF14880.6 KFH42354.1 - 0.0011 18.8 0.2 0.0017 18.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly vATP-synt_AC39 PF01992.16 KFH42355.1 - 2.2e-108 362.8 0.0 2.4e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ion_trans PF00520.31 KFH42356.1 - 1.9e-09 37.1 21.8 4.1e-09 36.0 21.8 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFH42356.1 - 4.3e-06 25.7 12.5 6.9e-06 25.0 1.2 2.1 1 1 1 2 2 2 2 Polycystin cation channel Band_7 PF01145.25 KFH42357.1 - 1.6e-28 99.9 3.4 1.6e-28 99.9 3.4 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFH42357.1 - 0.021 14.6 0.2 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Zn_clus PF00172.18 KFH42358.1 - 2e-07 31.0 8.6 4.3e-07 29.9 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH42358.1 - 0.0078 15.1 0.2 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.29 KFH42360.1 - 6.8e-37 126.9 0.0 1.7e-36 125.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH42360.1 - 1.5e-22 80.0 0.0 3.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFH42360.1 - 3.2e-20 72.1 0.0 6.1e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFH42360.1 - 0.0038 17.2 0.2 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit eIF3_subunit PF08597.10 KFH42360.1 - 1 9.3 22.4 2 8.3 22.4 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MRP-S26 PF14943.6 KFH42360.1 - 3.5 7.5 18.1 7.1 6.5 18.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 TMEM247 PF15444.6 KFH42362.1 - 0.0077 16.3 0.3 0.0093 16.0 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 Pribosyl_synth PF14572.6 KFH42363.1 - 1.9e-42 145.4 1.1 7.5e-38 130.4 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFH42363.1 - 1.1e-32 112.4 0.0 2.5e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFH42363.1 - 5.8e-15 55.2 0.2 1e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFH42363.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HSP70 PF00012.20 KFH42364.1 - 1.9e-60 204.7 3.9 5.4e-58 196.6 0.1 3.5 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFH42364.1 - 0.002 17.0 0.1 0.027 13.3 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DUF2730 PF10805.8 KFH42364.1 - 0.52 10.4 2.0 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Cir_N PF10197.9 KFH42365.1 - 3.5e-08 33.5 2.1 3.5e-08 33.5 2.1 4.7 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR E7 PF00527.18 KFH42365.1 - 1.6 9.0 7.5 0.76 10.0 0.1 3.0 3 0 0 3 3 3 0 E7 protein, Early protein DUF2937 PF11157.8 KFH42366.1 - 0.077 12.7 1.9 6.8 6.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) RasGEF PF00617.19 KFH42367.1 - 8.1e-49 166.2 0.2 1.3e-48 165.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFH42367.1 - 1.4e-13 51.0 0.1 3.5e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KFH42368.1 - 7.8e-22 77.6 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH42368.1 - 3e-08 33.9 0.0 6.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42368.1 - 3.3e-07 29.9 0.0 6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFH42368.1 - 0.013 14.7 0.2 0.03 13.5 0.1 1.5 1 1 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 KFH42368.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFH42368.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFH42368.1 - 0.053 13.3 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KFH42368.1 - 0.14 12.7 0.0 0.34 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFH42368.1 - 0.21 11.1 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_S15 PF00312.22 KFH42370.1 - 6.8e-24 83.9 1.6 4.1e-23 81.4 0.7 2.5 2 0 0 2 2 2 1 Ribosomal protein S15 SAE2 PF08573.10 KFH42370.1 - 1.7 9.8 9.4 0.23 12.6 0.8 2.8 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus U1snRNP70_N PF12220.8 KFH42370.1 - 2.5 8.8 10.3 0.37 11.5 1.4 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PIG-H PF10181.9 KFH42371.1 - 1.6e-26 91.9 0.0 2.3e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component CRM1_C PF08767.11 KFH42372.1 - 8.7e-133 442.4 2.2 8.7e-133 442.4 2.2 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KFH42372.1 - 4.4e-41 140.4 12.1 7.7e-41 139.6 7.2 3.6 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFH42372.1 - 1.3e-33 114.5 4.2 4.2e-33 112.8 4.2 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFH42372.1 - 9.8e-28 96.0 1.2 9.8e-28 96.0 1.2 3.2 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFH42372.1 - 2.2e-19 68.6 2.3 6e-19 67.3 2.3 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFH42372.1 - 1.1e-12 47.7 0.0 4e-12 45.9 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KFH42372.1 - 0.012 15.5 6.7 0.32 10.9 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KFH42372.1 - 0.033 13.4 0.2 0.16 11.1 0.1 2.1 2 1 0 2 2 2 0 Hemocyanin, copper containing domain DRIM PF07539.12 KFH42372.1 - 0.067 11.5 4.5 0.28 9.5 0.1 2.5 2 1 0 2 2 2 0 Down-regulated in metastasis HD_assoc PF13286.6 KFH42372.1 - 0.11 13.1 0.5 69 4.1 0.0 4.2 5 0 0 5 5 4 0 Phosphohydrolase-associated domain MMS19_C PF12460.8 KFH42372.1 - 0.8 8.7 13.0 0.041 13.0 1.1 3.9 3 2 2 5 5 5 0 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KFH42372.1 - 1.1 9.8 4.9 6.6 7.4 0.0 4.6 7 0 0 7 7 5 0 Vacuolar 14 Fab1-binding region Nop PF01798.18 KFH42373.1 - 1.9e-78 263.1 0.1 1.9e-78 263.1 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFH42373.1 - 2.4e-21 75.9 2.0 2.4e-21 75.9 2.0 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Fringe PF02434.16 KFH42374.1 - 2.7e-06 27.0 0.7 5.2e-05 22.8 0.7 2.2 1 1 0 1 1 1 1 Fringe-like Inhibitor_I68 PF10468.9 KFH42374.1 - 0.27 11.7 4.9 0.18 12.2 1.4 2.3 2 0 0 2 2 2 0 Carboxypeptidase inhibitor I68 NAD_binding_1 PF00175.21 KFH42375.1 - 4.8e-22 78.7 0.0 9.5e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFH42375.1 - 9.9e-19 67.5 0.0 2.2e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFH42375.1 - 3.8e-05 23.9 0.0 0.0043 17.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain ANAPC10 PF03256.16 KFH42376.1 - 2.6e-48 164.1 0.0 4.1e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PPP4R2 PF09184.11 KFH42376.1 - 0.025 14.2 2.4 0.035 13.7 2.4 1.1 1 0 0 1 1 1 0 PPP4R2 Virul_Fac PF10139.9 KFH42376.1 - 0.19 9.9 1.0 0.25 9.5 1.0 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor Nop14 PF04147.12 KFH42376.1 - 1.1 7.4 13.1 1.4 7.1 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KFH42376.1 - 2.8 7.2 8.4 4 6.7 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein ATP-grasp_2 PF08442.10 KFH42377.1 - 7.8e-76 254.1 1.7 1.1e-75 253.6 0.3 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFH42377.1 - 7.8e-28 97.2 0.4 1.6e-27 96.2 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFH42377.1 - 4.1e-09 36.2 0.1 9.1e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFH42377.1 - 5.8e-05 22.9 0.8 0.0011 18.7 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 KFH42377.1 - 0.022 15.0 0.1 0.46 10.8 0.0 2.7 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain RimK PF08443.11 KFH42377.1 - 0.068 12.8 0.0 1.5 8.4 0.0 2.4 1 1 1 2 2 2 0 RimK-like ATP-grasp domain KxDL PF10241.9 KFH42378.1 - 1.2e-32 112.0 1.5 1.7e-32 111.5 1.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 KFH42378.1 - 0.055 13.2 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism OmpH PF03938.14 KFH42378.1 - 2.9 8.2 9.2 5.9 7.2 9.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SNRNP27 PF08648.12 KFH42380.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins RPAP2_Rtr1 PF04181.13 KFH42381.1 - 2.9e-22 78.8 0.0 4.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family JAB PF01398.21 KFH42382.1 - 1.3e-08 34.8 0.6 2.4e-07 30.7 0.6 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TGT PF01702.18 KFH42384.1 - 7.9e-139 462.7 0.0 9.4e-139 462.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Transferase PF02458.15 KFH42385.1 - 0.00028 19.7 0.0 0.00048 18.9 0.0 1.5 1 1 0 1 1 1 1 Transferase family DUF2064 PF09837.9 KFH42385.1 - 0.15 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) GCP_N_terminal PF17681.1 KFH42386.1 - 2.1e-24 86.7 0.0 3.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFH42386.1 - 4.5e-24 85.5 0.0 7.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Molybdopterin_N PF18364.1 KFH42386.1 - 0.2 11.7 0.5 2.2 8.4 0.0 2.9 4 0 0 4 4 4 0 Molybdopterin oxidoreductase N-terminal domain IPI_T4 PF11634.8 KFH42386.1 - 0.22 11.5 0.5 0.96 9.5 0.2 2.1 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 TRI12 PF06609.13 KFH42387.1 - 5.1e-45 154.0 19.6 6e-45 153.8 19.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH42387.1 - 9.2e-16 57.7 51.0 6.2e-15 55.0 47.0 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42387.1 - 5.6e-06 25.5 7.9 5.6e-06 25.5 7.9 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.16 KFH42388.1 - 2.8e-31 108.7 32.9 2.8e-31 108.7 32.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42388.1 - 7.7e-10 38.2 14.9 2.5e-09 36.5 14.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFH42388.1 - 0.0018 16.8 0.4 0.0029 16.1 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KFH42388.1 - 0.0081 15.1 3.9 0.0086 15.0 2.0 1.9 2 0 0 2 2 2 1 MFS_1 like family DUF4023 PF13215.6 KFH42388.1 - 0.23 11.5 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Methyltransf_33 PF10017.9 KFH42389.1 - 1.8e-60 204.7 0.0 3.3e-44 151.3 0.0 2.2 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KFH42389.1 - 9.5e-19 68.0 0.4 3.3e-17 62.9 0.4 2.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KFH42389.1 - 1.5e-07 31.9 1.2 1.5e-07 31.9 1.2 2.9 4 0 0 4 4 4 1 DinB superfamily DUF3431 PF11913.8 KFH42391.1 - 4.9e-85 284.7 0.0 5.9e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) adh_short_C2 PF13561.6 KFH42392.1 - 5.9e-62 209.3 1.6 6.7e-62 209.1 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH42392.1 - 7.9e-53 178.8 2.9 9.3e-53 178.6 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH42392.1 - 3.5e-15 56.4 0.5 4.9e-15 55.9 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH42392.1 - 0.0098 15.8 1.5 0.015 15.2 1.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFH42392.1 - 0.023 14.0 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rhodanese PF00581.20 KFH42392.1 - 0.041 14.4 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Rhodanese-like domain Polysacc_synt_2 PF02719.15 KFH42392.1 - 0.062 12.4 0.1 0.09 11.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.15 KFH42392.1 - 0.13 12.1 0.7 0.19 11.6 0.7 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ribosomal_S21 PF01165.20 KFH42393.1 - 2.6e-12 46.2 5.9 4.5e-12 45.5 5.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF1681 PF07933.14 KFH42394.1 - 4.1e-56 188.8 0.0 5.1e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) 2-Hacid_dh_C PF02826.19 KFH42395.1 - 1.6e-53 180.7 0.0 2.1e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH42395.1 - 1.9e-17 63.2 0.0 2.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFH42395.1 - 0.00011 22.5 0.1 0.00016 21.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFH42395.1 - 0.0074 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain YhfC PF10086.9 KFH42396.1 - 0.027 13.8 0.7 0.027 13.8 0.7 1.9 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease Zn_clus PF00172.18 KFH42399.1 - 0.018 15.2 15.7 0.029 14.5 15.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M43 PF05572.13 KFH42400.1 - 3.8e-17 62.6 0.1 7.6e-17 61.6 0.1 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KFH42400.1 - 2.2e-05 24.7 0.2 3.5e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFH42400.1 - 2.8e-05 24.6 0.1 5.5e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFH42400.1 - 7.5e-05 22.5 0.3 0.00014 21.6 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFH42400.1 - 0.00081 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 KFH42400.1 - 0.0092 15.9 0.2 0.015 15.2 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KFH42400.1 - 0.061 13.4 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KFH42400.1 - 0.081 11.9 0.7 0.13 11.2 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 KFH42400.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 KFH42400.1 - 0.16 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 Mit_ribos_Mrp51 PF11709.8 KFH42401.1 - 5.2e-112 375.0 0.0 6.3e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit AdoHcyase PF05221.17 KFH42402.1 - 2.5e-129 430.7 0.0 2.9e-74 249.9 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFH42402.1 - 2.6e-83 277.9 1.7 4.1e-83 277.3 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFH42402.1 - 6.9e-07 28.8 0.1 1.4e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFH42402.1 - 0.0034 17.0 0.3 0.0062 16.1 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KFH42402.1 - 0.02 14.6 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 KFH42402.1 - 0.032 14.1 0.3 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFH42402.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SH3_1 PF00018.28 KFH42403.1 - 2.4e-10 39.8 0.2 6.3e-10 38.5 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH42403.1 - 4.4e-09 36.1 0.3 9.3e-09 35.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH42403.1 - 2.5e-08 33.5 0.0 5.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Fungal_trans PF04082.18 KFH42404.1 - 3.8e-23 81.9 0.0 6.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42404.1 - 9.6e-06 25.6 6.5 2e-05 24.6 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mto2_bdg PF12808.7 KFH42404.1 - 0.042 14.2 2.1 0.13 12.5 2.1 1.9 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CtsR_C PF17727.1 KFH42404.1 - 0.12 12.5 0.3 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain PikAIV_N PF18605.1 KFH42404.1 - 0.22 11.1 3.1 0.54 9.9 3.1 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain UPF0147 PF03685.13 KFH42404.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Zn_clus PF00172.18 KFH42406.1 - 1.7e-09 37.6 8.9 2.8e-09 36.9 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 KFH42406.1 - 0.9 9.1 13.4 1.6 8.3 13.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KFH42406.1 - 6.6 4.7 10.3 8.5 4.3 10.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Abhydrolase_3 PF07859.13 KFH42407.1 - 3.2e-61 206.9 0.0 4.2e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH42407.1 - 2.8e-09 36.4 0.1 1.5e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFH42407.1 - 0.0074 15.8 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KFH42407.1 - 0.18 11.4 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Med22 PF06179.12 KFH42408.1 - 6.4e-17 61.7 0.0 7.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Abhydrolase_6 PF12697.7 KFH42409.1 - 7.1e-08 33.3 0.2 1.2e-07 32.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH42409.1 - 1.1e-06 28.2 0.1 1.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH42409.1 - 0.00046 19.9 0.1 0.00073 19.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KFH42409.1 - 0.061 12.9 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Senescence PF06911.12 KFH42410.1 - 4.6e-53 180.2 5.9 7.2e-53 179.6 5.9 1.3 1 0 0 1 1 1 1 Senescence-associated protein adh_short PF00106.25 KFH42411.1 - 8e-39 133.1 0.2 1.2e-38 132.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH42411.1 - 5.2e-33 114.5 0.2 9.2e-33 113.7 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH42411.1 - 1.4e-05 25.1 0.5 2.9e-05 24.1 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH42411.1 - 0.003 17.0 0.3 0.0053 16.3 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KFH42411.1 - 0.015 16.0 0.1 0.029 15.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_2 PF00890.24 KFH42411.1 - 0.059 12.5 0.6 0.098 11.7 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KFH42411.1 - 0.15 12.0 0.4 0.23 11.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFH42411.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 2 0 0 2 2 2 0 TrkA-N domain Bestrophin PF01062.21 KFH42412.1 - 1.6e-36 126.3 0.2 2.7e-36 125.5 0.2 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Nre_C PF04895.12 KFH42412.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal Nre, C-terminal IF-2B PF01008.17 KFH42413.1 - 1e-32 113.5 0.0 1.3e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4177 PF13783.6 KFH42413.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) FMO-like PF00743.19 KFH42414.1 - 6.3e-17 61.2 0.9 5.6e-15 54.8 0.4 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFH42414.1 - 1.9e-11 43.8 0.0 5.7e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH42414.1 - 2.7e-09 37.1 0.0 2.7e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFH42414.1 - 4.8e-07 29.2 0.0 1.8e-06 27.4 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFH42414.1 - 4.2e-05 22.9 0.0 0.0015 17.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH42414.1 - 7.9e-05 22.7 0.0 0.009 16.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KFH42414.1 - 0.32 10.5 4.0 11 5.5 0.2 3.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFH42415.1 - 1.1e-16 60.4 0.0 1.1e-15 57.2 0.1 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH42415.1 - 6.8e-12 45.4 0.0 2.5e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFH42415.1 - 1.8e-07 30.7 0.1 0.00067 18.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFH42415.1 - 0.0014 17.9 0.0 0.034 13.4 0.0 2.6 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH42415.1 - 0.0021 17.4 0.0 0.012 14.9 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH42415.1 - 0.0098 15.9 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFH42415.1 - 0.025 14.2 0.0 0.32 10.5 0.0 2.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF1640 PF07798.11 KFH42416.1 - 3.2e-54 183.6 7.2 1e-43 149.4 5.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KFH42416.1 - 0.019 14.4 0.1 0.062 12.7 0.0 1.8 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Lzipper-MIP1 PF14389.6 KFH42416.1 - 0.32 11.3 4.2 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 cwf21 PF08312.12 KFH42416.1 - 0.79 9.9 8.1 1.3 9.2 4.2 2.6 2 1 0 2 2 2 0 cwf21 domain BST2 PF16716.5 KFH42416.1 - 4.3 8.0 10.6 0.57 10.8 1.1 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 WD40 PF00400.32 KFH42418.1 - 4e-39 131.9 29.6 1.9e-08 34.8 0.4 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 KFH42418.1 - 1.1e-11 44.5 1.6 2.1e-11 43.5 1.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH42418.1 - 4.3e-11 42.4 1.5 1.1e-10 41.2 1.5 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KFH42418.1 - 2.4e-09 37.4 0.5 0.0065 16.7 0.0 5.9 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH42418.1 - 2.2e-08 33.2 7.6 0.05 12.3 0.1 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 KFH42418.1 - 0.0021 17.9 0.1 0.0055 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box PALB2_WD40 PF16756.5 KFH42418.1 - 1.2 7.9 5.6 15 4.4 0.1 3.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KFH42418.1 - 1.7 7.5 6.6 11 4.9 0.0 3.7 2 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_6 PF12697.7 KFH42419.1 - 1.3e-14 55.4 6.1 1.6e-13 51.8 6.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH42419.1 - 0.00027 20.7 0.0 0.0007 19.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH42419.1 - 0.00066 19.0 0.2 0.029 13.7 0.0 2.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 KFH42419.1 - 0.12 12.0 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) FSH1 PF03959.13 KFH42419.1 - 0.16 11.7 0.0 0.53 9.9 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) HAUS6_N PF14661.6 KFH42420.1 - 3.9e-61 206.6 3.3 7.6e-61 205.6 3.3 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus LPD22 PF18834.1 KFH42420.1 - 0.08 13.2 1.4 0.26 11.5 1.4 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 MAGI_u1 PF16663.5 KFH42420.1 - 3.6 7.7 6.3 1.7 8.8 0.5 2.8 1 1 1 2 2 2 0 Unstructured region on MAGI Ribosomal_S17e PF00833.18 KFH42421.1 - 4e-58 194.7 0.1 4.9e-58 194.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF2196 PF09962.9 KFH42422.1 - 7.3e-24 83.5 3.3 1.2e-23 82.9 3.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 KFH42422.1 - 0.17 12.2 0.1 0.24 11.7 0.1 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TCTP PF00838.17 KFH42423.1 - 1.8e-71 239.9 4.4 2e-71 239.7 4.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Chordopox_A33R PF05966.12 KFH42423.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Chordopoxvirus A33R protein Ribosomal_S20p PF01649.18 KFH42423.1 - 0.091 13.4 0.3 0.16 12.6 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 NDUF_B4 PF07225.12 KFH42424.1 - 0.048 13.6 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2944 PF11161.8 KFH42424.1 - 0.095 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) POB3_N PF17292.2 KFH42425.1 - 4.5e-31 107.1 0.7 1.5e-29 102.2 0.3 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KFH42425.1 - 1.7e-27 95.1 0.1 1.2e-26 92.4 0.0 2.5 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KFH42425.1 - 3.4e-23 81.9 0.0 3.1e-22 78.8 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SDA1 PF05285.12 KFH42425.1 - 2.9 7.2 24.6 6.1 6.2 24.6 1.6 1 0 0 1 1 1 0 SDA1 Mis12 PF05859.12 KFH42426.1 - 4.7e-41 140.0 0.0 8.5e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein YL1 PF05764.13 KFH42427.1 - 1e-73 248.5 36.6 1e-73 248.5 36.6 3.1 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 KFH42427.1 - 1.9e-14 53.1 0.2 3.2e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GST_N_3 PF13417.6 KFH42428.1 - 2.3e-07 31.1 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFH42428.1 - 2.1e-06 27.9 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH42428.1 - 5e-06 26.5 0.3 1.2e-05 25.2 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFH42428.1 - 1.3e-05 25.5 0.0 4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KFH42428.1 - 0.00037 21.0 0.0 0.00072 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH42428.1 - 0.0022 18.1 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH42428.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBD PF00786.28 KFH42429.1 - 0.0029 17.9 0.2 0.029 14.7 0.1 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Alg6_Alg8 PF03155.15 KFH42430.1 - 1.7e-172 574.8 26.4 1.9e-172 574.6 26.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Mg_trans_NIPA PF05653.14 KFH42431.1 - 3e-57 194.0 7.8 2e-55 188.0 4.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KFH42431.1 - 0.00078 19.6 22.9 0.033 14.4 1.3 4.1 3 1 1 4 4 4 2 EamA-like transporter family DUF4131 PF13567.6 KFH42431.1 - 0.089 12.4 4.8 1.1 8.9 0.0 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Gaa1 PF04114.14 KFH42431.1 - 0.11 11.4 0.6 0.21 10.5 0.6 1.3 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component SLC35F PF06027.12 KFH42431.1 - 0.2 11.2 5.2 0.2 11.1 0.3 2.2 1 1 0 2 2 2 0 Solute carrier family 35 TssN PF17555.2 KFH42431.1 - 0.37 10.2 7.3 1.1 8.6 7.1 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF3180 PF11377.8 KFH42431.1 - 1.3 9.2 11.8 6.5 6.9 0.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3180) DUF1461 PF07314.11 KFH42431.1 - 1.6 8.6 5.3 0.61 10.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF373 PF04123.13 KFH42431.1 - 5.8 6.3 10.4 5.6 6.3 7.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Peptidase_M24 PF00557.24 KFH42432.1 - 2.2e-62 210.5 0.1 3.2e-62 209.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFH42432.1 - 5.3e-17 61.7 0.0 9.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RRM_1 PF00076.22 KFH42433.1 - 5.3e-64 212.0 0.0 2.8e-20 71.9 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KFH42433.1 - 4e-06 26.7 2.9 0.016 15.0 0.1 4.3 2 2 2 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KFH42433.1 - 5e-05 23.3 0.1 0.56 10.4 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFH42433.1 - 0.00012 22.4 13.5 0.77 10.0 0.0 6.8 5 3 2 7 7 7 3 Cytosolic domain of 10TM putative phosphate transporter Gti1_Pac2 PF09729.9 KFH42434.1 - 3.7e-54 183.6 0.1 3.6e-52 177.1 0.1 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family PRP4 PF08799.11 KFH42435.1 - 1.5e-12 46.8 0.6 1.5e-12 46.8 0.6 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 KFH42435.1 - 4.2e-07 30.1 0.1 4.2e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain Caldesmon PF02029.15 KFH42435.1 - 0.00058 18.8 18.1 0.00082 18.3 18.1 1.2 1 0 0 1 1 1 1 Caldesmon AP3D1 PF06375.11 KFH42435.1 - 0.17 12.1 11.5 0.39 10.9 11.5 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CDC45 PF02724.14 KFH42435.1 - 0.34 9.2 9.6 0.34 9.2 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Omp_AT PF11557.8 KFH42435.1 - 0.4 9.6 1.6 0.58 9.1 0.0 1.8 2 0 0 2 2 2 0 Solitary outer membrane autotransporter beta-barrel domain Phosphodiest PF01663.22 KFH42436.1 - 1.9e-11 44.2 0.5 8.3e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFH42436.1 - 2.9e-05 23.6 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFH42436.1 - 0.00035 20.0 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 KFH42436.1 - 0.041 12.5 0.1 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PINIT PF14324.6 KFH42437.1 - 8.8e-45 152.6 0.2 1.6e-44 151.8 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFH42437.1 - 3.2e-21 74.8 3.1 3.2e-21 74.8 3.1 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFH42437.1 - 9.9e-07 28.5 1.8 1.3e-06 28.1 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KFH42437.1 - 8.5e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 KFH42437.1 - 0.004 17.2 0.1 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger PROCN PF08083.11 KFH42438.1 - 4.1e-234 776.7 8.3 4.1e-234 776.7 8.3 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFH42438.1 - 1.1e-126 421.1 1.1 2e-126 420.2 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFH42438.1 - 3.9e-87 290.1 1.4 1.3e-86 288.4 1.4 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFH42438.1 - 3.6e-79 264.0 2.9 3.6e-79 264.0 2.9 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFH42438.1 - 1.6e-70 235.4 0.1 3.5e-70 234.3 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KFH42438.1 - 1e-45 154.6 0.2 2.8e-45 153.2 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 KFH42438.1 - 1.8e-45 153.2 0.1 4.7e-45 151.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PPR_2 PF13041.6 KFH42440.1 - 2.4e-17 62.9 0.0 2.5e-08 34.0 0.0 6.5 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.6 KFH42440.1 - 2.5e-11 43.5 0.0 0.00015 21.8 0.0 4.7 4 2 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFH42440.1 - 7.7e-06 25.4 0.0 0.00087 18.7 0.0 3.0 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFH42440.1 - 1.8e-05 24.6 0.9 3.4 8.1 0.0 5.5 5 1 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 KFH42440.1 - 0.0099 15.6 0.1 1.5 8.6 0.0 4.1 4 0 0 4 4 4 1 PPR repeat Pox_Ag35 PF03286.14 KFH42440.1 - 0.021 14.7 5.6 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Rab_bind PF16704.5 KFH42440.1 - 0.028 14.4 0.2 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Rab binding domain TPR_6 PF13174.6 KFH42440.1 - 0.26 12.0 1.0 30 5.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42440.1 - 1 10.3 8.8 39 5.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 KFH42440.1 - 2.7 8.4 5.7 1.6 9.2 0.0 3.4 5 0 0 5 5 5 0 Bacterial transcriptional activator domain SAP18 PF06487.12 KFH42441.1 - 3.3e-24 85.7 0.0 4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) FA_hydroxylase PF04116.13 KFH42442.1 - 1.1e-24 87.3 15.7 1.6e-24 86.7 12.7 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WAC_Acf1_DNA_bd PF10537.9 KFH42443.1 - 2.8e-22 79.1 2.3 3e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KFH42443.1 - 5.5e-20 71.7 0.3 5.5e-20 71.7 0.3 3.6 5 0 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KFH42443.1 - 2.1e-16 60.0 0.4 4.4e-16 58.9 0.4 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KFH42443.1 - 6.7e-09 35.1 0.1 2.7e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 CCDC-167 PF15188.6 KFH42443.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.8 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 Nexin_C PF08628.12 KFH42443.1 - 3.5 8.3 5.7 7.7 7.1 1.9 3.2 2 0 0 2 2 2 0 Sorting nexin C terminal Lipase_3 PF01764.25 KFH42444.1 - 7.7e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KFH42444.1 - 0.003 16.9 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH42444.1 - 0.054 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KFH42444.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 KFH42444.1 - 0.21 11.4 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lectin_leg-like PF03388.13 KFH42445.1 - 5.1e-24 84.9 0.0 8.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF2353 PF09789.9 KFH42445.1 - 0.004 16.6 5.1 0.0062 15.9 5.1 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 KFH42445.1 - 0.0043 17.5 1.6 0.0074 16.8 1.6 1.3 1 0 0 1 1 1 1 Fez1 BLOC1_2 PF10046.9 KFH42445.1 - 0.0072 16.6 0.8 0.014 15.7 0.8 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 KFH42445.1 - 0.014 13.4 0.4 0.018 13.1 0.4 1.1 1 0 0 1 1 1 0 Prominin FUSC PF04632.12 KFH42445.1 - 0.019 13.6 0.7 0.027 13.0 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pox_A_type_inc PF04508.12 KFH42445.1 - 0.032 14.1 1.9 0.097 12.6 1.9 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Macoilin PF09726.9 KFH42445.1 - 0.033 12.8 4.4 0.045 12.3 4.4 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 KFH42445.1 - 0.044 13.9 4.5 0.065 13.3 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFH42445.1 - 0.046 12.6 3.2 0.067 12.1 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KFH42445.1 - 0.05 13.1 6.8 0.069 12.6 6.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF848 PF05852.11 KFH42445.1 - 0.052 13.7 1.7 0.082 13.0 1.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ATG16 PF08614.11 KFH42445.1 - 0.057 13.7 6.6 0.084 13.1 6.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SAGA-Tad1 PF12767.7 KFH42445.1 - 0.059 13.1 3.1 0.085 12.6 3.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1664 PF07889.12 KFH42445.1 - 0.06 13.4 2.9 0.1 12.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KFH42445.1 - 0.087 12.5 6.9 0.18 11.4 6.9 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 KFH42445.1 - 0.09 13.1 1.9 0.18 12.1 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1192 PF06698.11 KFH42445.1 - 0.13 12.3 1.4 0.3 11.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Rbsn PF11464.8 KFH42445.1 - 0.14 11.9 0.6 0.28 10.9 0.6 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Exonuc_VII_L PF02601.15 KFH42445.1 - 0.19 11.2 3.5 0.27 10.8 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TssO PF17561.2 KFH42445.1 - 0.3 11.2 1.1 0.56 10.3 0.8 1.6 2 0 0 2 2 1 0 Type VI secretion system, TssO Pox_A11 PF05061.13 KFH42445.1 - 0.45 9.8 2.3 0.64 9.2 2.3 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Occludin_ELL PF07303.13 KFH42445.1 - 0.6 10.9 3.9 1.3 9.8 3.8 1.6 1 1 0 1 1 1 0 Occludin homology domain Fzo_mitofusin PF04799.13 KFH42445.1 - 0.63 9.6 2.1 1.1 8.7 2.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 KFH42445.1 - 0.73 9.0 2.5 1.1 8.4 2.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KFH42445.1 - 1.1 9.1 6.3 2.1 8.2 3.1 2.7 2 1 0 2 2 1 0 Septum formation initiator Fib_alpha PF08702.10 KFH42445.1 - 1.3 9.2 3.7 2.9 8.1 3.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KFH42445.1 - 1.3 9.7 4.2 2.2 9.0 0.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KFH42445.1 - 2.3 8.7 8.0 0.84 10.1 0.5 2.3 1 1 1 2 2 2 0 Cell division protein ZapB CCDC-167 PF15188.6 KFH42445.1 - 3.3 8.1 7.0 7 7.1 7.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 KFH42445.1 - 8.2 5.7 5.9 0.89 8.8 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 KFH42447.1 - 6.3e-29 100.8 0.4 9e-29 100.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42447.1 - 1e-10 41.5 13.6 1.9e-10 40.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2 PF00111.27 KFH42447.1 - 0.22 11.5 2.3 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Galactosyl_T PF01762.21 KFH42448.1 - 0.15 11.8 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase SUIM_assoc PF16619.5 KFH42449.1 - 0.0054 16.8 4.2 0.01 15.9 4.2 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 GARS_A PF01071.19 KFH42450.1 - 1.3e-83 279.6 0.0 2.2e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KFH42450.1 - 4.9e-35 120.2 0.0 1.9e-34 118.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KFH42450.1 - 1.5e-31 109.7 0.0 3.4e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KFH42450.1 - 2.9e-26 91.6 0.6 3.7e-25 88.0 0.3 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFH42450.1 - 1.4e-14 54.5 1.8 4.8e-14 52.8 1.7 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KFH42450.1 - 0.00043 19.9 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFH42450.1 - 0.00051 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KFH42450.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 KFH42450.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KFH42450.1 - 0.19 11.0 0.0 0.5 9.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RPN7 PF10602.9 KFH42451.1 - 2.8e-44 150.9 0.1 7.1e-44 149.6 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KFH42451.1 - 4.5e-17 62.5 0.7 3.8e-16 59.5 0.0 2.6 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFH42451.1 - 0.00015 21.6 2.5 2.9 8.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH42451.1 - 0.11 12.4 0.1 23 5.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd3 PF12719.7 KFH42452.1 - 7.5e-91 304.4 1.4 1.8e-90 303.1 0.1 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFH42452.1 - 8.5e-10 38.9 6.9 1.1e-05 25.7 0.8 4.9 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KFH42452.1 - 1.2e-07 31.3 11.1 0.08 13.2 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KFH42452.1 - 0.00028 21.0 4.7 0.083 12.9 0.1 4.8 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFH42452.1 - 0.04 12.5 1.4 0.61 8.6 0.0 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFH42452.1 - 0.048 14.3 0.0 0.41 11.3 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KFH42452.1 - 0.14 12.4 0.6 12 6.1 0.0 3.7 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KFH42452.1 - 2.1 8.9 6.6 8.2 7.1 0.0 5.1 7 0 0 7 7 7 0 HEAT-like repeat DUF2423 PF10338.9 KFH42453.1 - 9.1e-19 67.4 3.4 9.1e-19 67.4 3.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) DUF3982 PF13138.6 KFH42453.1 - 0.037 13.8 0.1 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) FAD_binding_3 PF01494.19 KFH42454.1 - 1.6e-12 47.4 1.8 0.00033 20.0 0.3 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 KFH42454.1 - 8.1e-06 26.3 0.3 1.9e-05 25.1 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH42454.1 - 6e-05 23.2 0.2 0.00015 21.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH42454.1 - 7.3e-05 22.0 0.2 0.00028 20.1 0.4 1.7 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH42454.1 - 0.0001 21.7 0.2 0.0002 20.7 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH42454.1 - 0.00012 20.9 0.5 0.00018 20.3 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KFH42454.1 - 0.00017 21.1 0.1 0.0033 16.8 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFH42454.1 - 0.0022 17.7 1.0 0.018 14.6 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH42454.1 - 0.018 14.4 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFH42454.1 - 0.045 13.0 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH42454.1 - 0.24 10.6 0.1 0.87 8.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family BAR PF03114.18 KFH42455.1 - 1.1e-66 224.9 4.9 1.4e-66 224.6 4.9 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KFH42455.1 - 0.0074 17.0 0.1 0.041 14.6 0.0 2.3 3 0 0 3 3 3 1 CP12 domain BRE1 PF08647.11 KFH42455.1 - 1.7 8.8 7.6 0.4 10.8 2.0 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase SVIP PF15811.5 KFH42455.1 - 2 8.9 6.7 0.24 11.9 0.6 2.3 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Pept_tRNA_hydro PF01195.19 KFH42456.1 - 8.3e-27 94.2 0.0 9.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SMRP1 PF15181.6 KFH42456.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 PLDc_2 PF13091.6 KFH42458.1 - 1.3e-18 67.2 0.0 5.3e-11 42.5 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFH42458.1 - 9.9e-05 22.4 0.1 0.018 15.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Zn_clus PF00172.18 KFH42459.1 - 1.6e-10 40.9 10.9 2.5e-10 40.3 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH42459.1 - 4.7e-06 25.8 1.3 2.7e-05 23.3 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KFH42460.1 - 4.6e-61 207.0 0.5 5.6e-61 206.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L13 PF00572.18 KFH42461.1 - 5.1e-12 46.1 0.0 6.1e-10 39.4 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 KFH42461.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TauD PF02668.16 KFH42462.1 - 2.3e-29 103.0 0.4 3.2e-29 102.6 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFH42462.1 - 0.014 14.6 0.2 0.023 13.8 0.2 1.3 1 0 0 1 1 1 0 CsiD Adap_comp_sub PF00928.21 KFH42464.1 - 8.5e-84 281.0 0.0 1.1e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFH42464.1 - 2.4e-05 24.3 0.2 4.4e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LIDHydrolase PF10230.9 KFH42465.1 - 2.7e-58 197.6 0.0 3.2e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KFH42465.1 - 0.00033 21.3 7.0 0.0004 21.1 7.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH42465.1 - 0.045 13.0 0.1 0.085 12.1 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFH42465.1 - 0.054 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFH42465.1 - 0.069 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KFH42466.1 - 3.5e-40 138.0 51.8 3.5e-40 138.0 51.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH42466.1 - 3.7e-16 58.7 12.8 6.1e-16 58.0 12.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH42466.1 - 4.5e-12 45.6 12.0 4.5e-12 45.6 12.0 4.1 4 0 0 4 4 4 1 Sugar (and other) transporter BAR PF03114.18 KFH42468.1 - 9.5e-48 162.9 5.3 1.1e-47 162.7 5.3 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFH42468.1 - 1.3e-06 27.8 1.2 1.5e-06 27.6 1.2 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CheZ PF04344.13 KFH42468.1 - 0.24 11.3 2.0 0.38 10.6 2.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Arfaptin PF06456.13 KFH42468.1 - 0.36 10.4 6.3 0.98 8.9 4.1 2.3 2 1 0 2 2 2 0 Arfaptin-like domain FAM184 PF15665.5 KFH42468.1 - 0.67 9.7 8.9 0.49 10.2 5.7 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 KFH42468.1 - 6.9 6.1 6.8 11 5.5 6.4 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Exo_endo_phos PF03372.23 KFH42469.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ammonium_transp PF00909.21 KFH42470.1 - 1.6e-117 392.6 26.3 1.8e-117 392.4 26.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family EVC2_like PF12297.8 KFH42470.1 - 0.09 11.5 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Cyclin_C_2 PF16899.5 KFH42471.1 - 7.3e-33 113.1 0.1 2.6e-31 108.1 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KFH42471.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ALIX_LYPXL_bnd PF13949.6 KFH42471.1 - 0.85 8.9 3.1 0.8 8.9 0.1 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Sugar_tr PF00083.24 KFH42472.1 - 5.5e-73 246.4 24.8 6.3e-73 246.2 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42472.1 - 2.7e-21 75.9 30.4 5.1e-19 68.4 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KFH42472.1 - 0.021 13.2 0.4 0.021 13.2 0.4 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Chalcone_2 PF16035.5 KFH42473.1 - 3.1e-78 262.2 0.4 6.8e-78 261.1 0.0 1.6 2 0 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 KFH42473.1 - 0.0065 16.6 1.1 0.054 13.6 0.2 2.7 2 1 1 3 3 3 1 Chalcone isomerase-like GMC_oxred_N PF00732.19 KFH42474.1 - 2.5e-63 214.2 0.0 3.4e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH42474.1 - 1.3e-23 84.2 0.0 2.6e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFH42474.1 - 2.6e-06 26.8 1.3 0.039 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFH42474.1 - 2.4e-05 23.6 0.1 3.6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFH42474.1 - 0.0018 17.9 2.7 0.018 14.6 0.4 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH42474.1 - 0.0056 15.9 0.1 0.014 14.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFH42474.1 - 0.0084 16.3 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KFH42474.1 - 0.0091 14.9 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Mqo PF06039.15 KFH42474.1 - 0.042 12.4 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 KFH42474.1 - 0.066 12.5 0.3 2 7.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KFH42474.1 - 0.067 12.4 0.3 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KFH42474.1 - 0.36 10.1 1.1 6.6 6.0 0.2 2.2 2 0 0 2 2 2 0 ThiF family DCP1 PF06058.13 KFH42475.1 - 1.7e-29 102.2 0.0 2.2e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family CMD PF02627.20 KFH42476.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF1749 PF08538.10 KFH42476.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 KFH42477.1 - 3.5e-37 128.3 0.0 1.8e-36 126.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH42477.1 - 0.0022 16.9 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KFH42478.1 - 6.8e-19 68.5 0.1 3.2e-18 66.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH42478.1 - 4.2e-18 66.8 0.2 5.4e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH42478.1 - 5.3e-08 32.4 0.0 1.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFH42478.1 - 0.047 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.14 KFH42478.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 Ndr family DUF2373 PF10180.9 KFH42478.1 - 0.17 11.8 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) GST_C_2 PF13410.6 KFH42479.1 - 0.0026 17.7 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH42479.1 - 0.0063 16.7 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH42479.1 - 0.066 13.4 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BAG PF02179.16 KFH42481.1 - 1.1e-21 77.0 0.6 2.3e-21 76.0 0.6 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFH42481.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 KFH42481.1 - 0.0046 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KFH42481.1 - 0.007 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain TPR_2 PF07719.17 KFH42482.1 - 5.5e-11 41.7 5.9 0.00019 21.3 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFH42482.1 - 1e-08 34.6 2.0 0.011 15.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFH42482.1 - 1.8e-06 28.4 2.4 0.00023 21.6 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH42482.1 - 2.3e-06 28.1 1.3 0.0014 19.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH42482.1 - 2.6e-06 27.6 4.4 0.0021 18.3 0.2 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH42482.1 - 2.1e-05 24.4 0.7 0.011 15.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42482.1 - 0.001 19.7 6.8 0.015 16.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFH42482.1 - 0.028 14.1 3.0 1.1 9.0 0.7 3.1 3 0 0 3 3 3 0 TPR repeat ANAPC3 PF12895.7 KFH42482.1 - 0.034 14.4 0.1 0.071 13.3 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3293 PF11697.8 KFH42482.1 - 0.21 12.1 2.1 1.1 9.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3293) TPR_10 PF13374.6 KFH42482.1 - 0.22 11.5 9.9 15 5.6 0.3 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFH42482.1 - 0.54 11.0 7.2 0.72 10.7 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH42482.1 - 1.5 9.6 8.7 1.8 9.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Arb1 PF09692.10 KFH42484.1 - 0.21 10.7 0.0 0.24 10.5 0.0 1.0 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Zn_clus PF00172.18 KFH42485.1 - 0.11 12.6 5.6 0.26 11.4 5.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.17 KFH42487.1 - 2e-36 125.5 0.1 1.8e-35 122.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFH42487.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nic96 PF04097.14 KFH42487.1 - 0.26 9.7 0.0 0.38 9.1 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 SF1-HH PF16275.5 KFH42488.1 - 7e-44 148.8 1.1 7e-44 148.8 1.1 2.4 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KFH42488.1 - 1.8e-11 43.6 11.3 1.2e-05 25.1 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KFH42488.1 - 5.6e-08 32.5 0.2 1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KFH42488.1 - 7.4e-07 29.0 5.9 0.00039 20.3 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFH42488.1 - 0.00053 19.8 7.5 0.14 12.0 0.5 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFH42488.1 - 0.0016 18.1 5.0 0.54 10.0 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KFH42488.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 KFH42488.1 - 0.23 11.6 1.4 0.5 10.5 1.4 1.6 1 0 0 1 1 1 0 PHD-finger Prim_Zn_Ribbon PF08273.12 KFH42488.1 - 2.1 8.7 8.8 0.41 11.0 2.6 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Lipase_3 PF01764.25 KFH42489.1 - 1.8e-18 66.8 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Glyco_hydro_88 PF07470.13 KFH42490.1 - 5.8e-09 35.5 0.4 2.8e-08 33.2 0.4 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 LRR_6 PF13516.6 KFH42491.1 - 1.8e-15 55.6 26.4 0.043 13.9 0.0 12.0 13 0 0 13 13 13 7 Leucine Rich repeat F-box-like PF12937.7 KFH42491.1 - 2.2e-13 49.9 1.1 1.5e-12 47.2 1.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KFH42491.1 - 7.8e-10 38.9 20.4 0.47 11.0 0.0 7.5 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 KFH42491.1 - 0.00026 20.7 1.3 0.8 9.4 0.0 4.1 4 2 0 4 4 4 2 Protein of unknown function (DUF1699) F-box PF00646.33 KFH42491.1 - 0.00027 20.7 0.5 0.00027 20.7 0.5 2.6 2 1 0 2 2 2 1 F-box domain Fungal_trans PF04082.18 KFH42493.1 - 6.9e-16 58.1 0.1 1.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.24 KFH42494.1 - 3.1e-20 72.1 0.0 4.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFH42494.1 - 0.011 16.2 0.2 0.031 14.7 0.1 1.9 2 1 0 2 2 2 0 Thioredoxin-like domain DUF836 PF05768.14 KFH42494.1 - 0.017 15.5 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 KFH42494.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Peptidase_M24 PF00557.24 KFH42495.1 - 1.5e-21 77.0 0.2 2.3e-21 76.5 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KFH42495.1 - 1.5e-18 67.8 0.0 2.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain LSM PF01423.22 KFH42496.1 - 1.4e-15 56.7 0.1 1.7e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFH42496.1 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Glutaminase PF04960.15 KFH42497.1 - 4e-114 380.6 0.0 4.9e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Zip PF02535.22 KFH42498.1 - 3e-62 210.8 0.2 3.5e-62 210.6 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ferritin_2 PF13668.6 KFH42499.1 - 1.4e-07 31.8 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Ribosomal_S19e PF01090.19 KFH42500.1 - 7.6e-56 187.6 0.3 9.5e-56 187.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Citrate_synt PF00285.21 KFH42501.1 - 8.5e-123 410.0 0.0 1.1e-122 409.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Paf67 PF10255.9 KFH42502.1 - 7.5e-157 522.5 0.4 8.8e-157 522.2 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFH42502.1 - 0.04 14.0 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PEX11 PF05648.14 KFH42503.1 - 5.3e-33 114.4 0.0 7.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1467 PF07330.12 KFH42503.1 - 0.053 13.5 1.6 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) CorA PF01544.18 KFH42504.1 - 0.65 9.3 13.5 4 6.7 13.5 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Fmp27 PF10344.9 KFH42505.1 - 1.3e-207 691.9 0.0 1e-206 688.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KFH42505.1 - 2.9e-193 643.1 1.0 2.9e-193 643.1 1.0 2.8 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KFH42505.1 - 5.8e-183 609.2 0.8 4.3e-182 606.3 0.1 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KFH42505.1 - 9.9e-57 191.2 0.4 2.3e-56 190.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KFH42505.1 - 2.3e-56 190.3 0.0 4.8e-56 189.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KFH42505.1 - 1.4e-30 106.1 0.0 4.5e-30 104.4 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4034 PF13226.6 KFH42506.1 - 0.091 12.1 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Dynamin_N PF00350.23 KFH42507.1 - 1.7e-32 112.8 0.0 3.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH42507.1 - 1.2e-31 110.0 0.1 1.3e-30 106.6 0.1 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFH42507.1 - 0.00027 21.0 0.0 0.0013 18.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase NPH3 PF03000.14 KFH42507.1 - 0.014 15.0 0.4 0.31 10.6 0.0 2.5 2 1 0 2 2 2 0 NPH3 family AAA_23 PF13476.6 KFH42507.1 - 0.37 11.3 1.7 12 6.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF445 PF04286.12 KFH42507.1 - 1.4 8.6 8.4 16 5.2 3.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) ABA_GPCR PF12430.8 KFH42508.1 - 6.2e-50 169.5 0.1 6.2e-50 169.5 0.1 1.9 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFH42508.1 - 3.9e-24 84.5 0.0 9.3e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF4716 PF15837.5 KFH42508.1 - 0.068 13.3 2.1 0.19 11.8 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4716) Fungal_trans_2 PF11951.8 KFH42511.1 - 1.4e-07 30.6 1.0 0.003 16.4 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Beta_elim_lyase PF01212.21 KFH42513.1 - 2.5e-75 253.5 0.0 3.5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase EthD PF07110.11 KFH42514.1 - 2.8e-13 50.8 0.2 3.9e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFH42514.1 - 6.8e-09 36.2 0.1 9.5e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF4372 PF14294.6 KFH42514.1 - 0.17 12.1 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) JAB PF01398.21 KFH42515.1 - 9e-30 103.1 0.1 1.5e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFH42515.1 - 1.2e-22 80.6 0.5 2.3e-22 79.7 0.5 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFH42515.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAD_binding_4 PF01565.23 KFH42516.1 - 8.1e-21 74.2 1.7 4.9e-20 71.7 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KFH42516.1 - 3e-06 27.2 0.0 6.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KFH42518.1 - 6.9e-25 87.4 1.6 1.3e-24 86.5 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH42518.1 - 4.4e-10 39.5 1.0 9.1e-10 38.5 1.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KFH42518.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Secretin_N_2 PF07655.13 KFH42518.1 - 0.47 11.0 12.9 1 10.0 12.9 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 KFH42518.1 - 2 6.7 5.5 3 6.1 5.5 1.2 1 0 0 1 1 1 0 Menin GTP_EFTU PF00009.27 KFH42519.1 - 2.8e-57 193.4 0.0 4.6e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFH42519.1 - 2.3e-16 59.6 0.0 5.7e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFH42519.1 - 5.1e-10 39.6 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFH42519.1 - 1.1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KFH42519.1 - 2e-05 24.4 0.0 0.00094 19.0 0.0 2.9 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KFH42519.1 - 0.028 14.5 0.0 0.098 12.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_3 PF07859.13 KFH42520.1 - 1.6e-51 175.1 0.0 2.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH42520.1 - 8.4e-09 34.8 0.0 3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFH42520.1 - 0.00029 20.4 0.0 0.00087 18.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFH42520.1 - 0.0025 17.4 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KFH42520.1 - 0.014 14.1 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CBP_BcsO PF17037.5 KFH42520.1 - 0.04 14.1 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Esterase_phd PF10503.9 KFH42520.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KFH42520.1 - 0.11 13.1 4.1 0.17 12.4 1.9 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family CFEM PF05730.11 KFH42521.1 - 7.7e-05 22.7 5.5 0.00013 22.0 5.5 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_61 PF03443.14 KFH42522.1 - 8.5e-62 208.7 0.1 1e-61 208.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 KFH42522.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) RRM_1 PF00076.22 KFH42523.1 - 1.5e-12 47.2 0.0 2.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Usp PF00582.26 KFH42524.1 - 9.6e-13 48.8 5.7 2.6e-05 24.7 0.1 3.6 3 1 1 4 4 4 2 Universal stress protein family DUF4449 PF14613.6 KFH42525.1 - 1.4e-65 220.4 2.0 1.4e-65 220.4 2.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) ExsD PF16806.5 KFH42525.1 - 0.0055 16.7 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 2 Antiactivator protein ExsD Prp18 PF02840.15 KFH42525.1 - 0.007 16.4 3.1 2.7 8.0 0.0 3.0 2 0 0 2 2 2 2 Prp18 domain adh_short PF00106.25 KFH42526.1 - 7e-44 149.6 1.9 1.1e-43 148.9 1.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH42526.1 - 8.3e-40 136.8 3.9 3.1e-39 134.9 3.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH42526.1 - 1.1e-09 38.5 1.3 1.3e-09 38.2 0.2 1.7 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KFH42526.1 - 0.003 17.6 0.1 0.005 16.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KFH42526.1 - 0.0047 17.4 1.1 0.059 13.8 1.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KFH42526.1 - 0.031 14.9 0.2 0.077 13.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFH42526.1 - 0.031 14.2 0.9 0.099 12.5 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KFH42526.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KFH42526.1 - 0.048 13.7 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFH42526.1 - 0.051 13.0 0.1 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFH42527.1 - 3.6e-18 65.7 0.0 2.1e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH42527.1 - 2.3e-09 37.2 0.0 2.8e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH42527.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3818 PF12825.7 KFH42528.1 - 3.8e-48 164.2 0.0 8.3e-45 153.3 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KFH42528.1 - 3.6e-40 137.0 0.0 8e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 PX-associated IL10 PF00726.17 KFH42528.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 Phage_TAC_11 PF11836.8 KFH42528.1 - 0.17 12.0 1.5 9.3 6.4 0.1 3.1 2 1 0 2 2 2 0 Phage tail tube protein, GTA-gp10 TSP_1 PF00090.19 KFH42529.1 - 0.026 14.8 3.0 0.073 13.3 3.0 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain VirB8 PF04335.13 KFH42529.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 VirB8 protein Peptidase_M20 PF01546.28 KFH42530.1 - 2.1e-30 106.0 0.0 4e-30 105.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFH42530.1 - 4e-13 49.2 0.0 6.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFH42530.1 - 0.003 17.3 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 MDM10 PF12519.8 KFH42531.1 - 1.1e-164 548.8 0.0 7.8e-138 460.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KFH42531.1 - 0.046 13.2 0.0 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic porin zf-3CxxC PF13695.6 KFH42532.1 - 4.9e-23 81.5 0.4 7.2e-23 80.9 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding domain DUF905 PF06006.12 KFH42533.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) adh_short PF00106.25 KFH42534.1 - 3.9e-42 143.9 0.0 6.1e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH42534.1 - 7.9e-26 91.0 0.2 1.1e-25 90.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH42534.1 - 1.9e-07 31.2 0.2 2.8e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH42534.1 - 3.3e-07 30.0 0.2 8.8e-07 28.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFH42534.1 - 4.8e-05 23.3 0.4 8.7e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KFH42534.1 - 0.00085 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KFH42534.1 - 0.023 14.3 0.2 0.036 13.6 0.2 1.4 1 1 0 1 1 1 0 NmrA-like family Sterol_MT_C PF08498.10 KFH42535.1 - 2.4e-29 101.5 0.1 4.3e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KFH42535.1 - 5.4e-22 78.3 0.0 1.5e-21 76.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH42535.1 - 4.4e-20 72.2 0.0 1.1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH42535.1 - 5.3e-18 65.3 0.0 8.7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH42535.1 - 7.2e-12 45.1 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFH42535.1 - 9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFH42535.1 - 9.8e-12 44.7 0.1 1.5e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFH42535.1 - 5.7e-11 43.0 0.0 2.8e-10 40.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFH42535.1 - 0.00047 19.7 0.0 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFH42535.1 - 0.00053 19.6 0.1 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 KFH42535.1 - 0.00058 18.5 0.0 0.00097 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KFH42535.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KFH42535.1 - 0.00083 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KFH42535.1 - 0.0078 16.2 0.2 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KFH42535.1 - 0.0095 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KFH42535.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 KFH42535.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 KFH42535.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB ABC_membrane PF00664.23 KFH42537.1 - 9.2e-91 304.3 33.2 9.9e-47 159.9 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH42537.1 - 1.9e-65 219.5 0.0 1.9e-31 109.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH42537.1 - 6.1e-12 45.5 0.2 0.00047 19.7 0.0 4.0 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFH42537.1 - 5.9e-08 32.8 0.0 0.00075 19.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFH42537.1 - 6.9e-08 32.8 0.2 0.0032 17.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFH42537.1 - 4.2e-07 29.6 0.5 0.01 15.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH42537.1 - 7.2e-07 29.7 0.4 0.0022 18.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KFH42537.1 - 6.9e-05 21.8 0.3 0.35 9.6 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KFH42537.1 - 0.00026 20.8 0.0 0.61 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFH42537.1 - 0.00066 19.6 0.1 1 9.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFH42537.1 - 0.00089 19.4 1.6 0.82 9.9 0.1 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KFH42537.1 - 0.00094 18.8 0.4 1.5 8.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KFH42537.1 - 0.00097 19.7 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH42537.1 - 0.004 16.9 4.2 4.5 6.9 0.4 3.9 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KFH42537.1 - 0.004 17.4 0.4 0.61 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KFH42537.1 - 0.0045 16.2 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 KFH42537.1 - 0.016 14.7 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFH42537.1 - 0.016 15.3 0.3 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFH42537.1 - 0.019 14.3 0.1 4.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 KFH42537.1 - 0.019 15.0 0.0 4.7 7.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KFH42537.1 - 0.027 14.4 0.1 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 KFH42537.1 - 0.027 15.0 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFH42537.1 - 0.041 13.9 0.4 24 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KFH42537.1 - 0.053 13.6 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SH3_3 PF08239.11 KFH42537.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Rop-like PF05082.13 KFH42537.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Rop-like SRP54 PF00448.22 KFH42537.1 - 0.14 11.8 0.2 11 5.6 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFH42537.1 - 0.15 11.8 0.1 13 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFH42537.1 - 0.15 11.9 0.1 29 4.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KFH42537.1 - 0.2 12.1 0.2 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Complex1_LYR PF05347.15 KFH42539.1 - 3.1e-06 27.2 0.1 4.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFH42539.1 - 0.0026 18.5 0.2 0.003 18.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ADH_N PF08240.12 KFH42540.1 - 3.8e-21 75.0 0.1 1.1e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH42540.1 - 2.7e-19 69.4 1.1 4e-19 68.9 1.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH42540.1 - 2.9e-07 31.6 0.3 4.8e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Diphtheria_C PF02763.14 KFH42540.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Swi3 PF07962.12 KFH42542.1 - 3.4e-29 100.6 0.0 5.3e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Amidase PF01425.21 KFH42543.1 - 1.1e-120 403.7 0.0 1.4e-120 403.4 0.0 1.1 1 0 0 1 1 1 1 Amidase HTH_13 PF11972.8 KFH42543.1 - 0.0096 16.0 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain zf-C2H2_jaz PF12171.8 KFH42544.1 - 4.6e-07 30.0 2.0 6.8e-07 29.4 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH42544.1 - 0.00057 20.2 1.0 0.00097 19.4 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFH42544.1 - 0.05 14.1 0.9 0.097 13.2 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH42544.1 - 0.052 14.4 0.4 0.1 13.5 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFH42544.1 - 0.13 12.6 0.2 0.2 12.0 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2057 PF09829.9 KFH42544.1 - 0.15 12.3 1.3 3.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) F-box-like PF12937.7 KFH42545.1 - 1.4e-11 44.1 0.7 2.8e-11 43.1 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH42545.1 - 4.6e-08 32.8 0.1 9.7e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFH42545.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box Ribonuclease_T2 PF00445.18 KFH42546.1 - 2.5e-44 151.7 0.2 3.8e-44 151.1 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family PEP_mutase PF13714.6 KFH42547.1 - 2.9e-52 177.5 0.3 3.5e-52 177.2 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFH42547.1 - 3.1e-11 42.5 0.1 5e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KFH42547.1 - 0.0013 18.2 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase p450 PF00067.22 KFH42548.1 - 2.9e-34 118.6 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRIP PF01465.20 KFH42549.1 - 1.8e-15 56.6 0.0 4.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 GRIP domain EzrA PF06160.12 KFH42549.1 - 7.2e-05 21.2 51.6 7.2e-05 21.2 51.6 5.3 4 1 0 4 4 4 3 Septation ring formation regulator, EzrA TolA_bind_tri PF16331.5 KFH42549.1 - 0.00029 20.8 2.2 0.00029 20.8 2.2 11.4 5 4 6 11 11 10 3 TolA binding protein trimerisation DHR10 PF18595.1 KFH42549.1 - 0.00092 19.3 169.4 0.0011 19.0 21.1 10.9 3 2 5 10 10 10 3 Designed helical repeat protein 10 domain Spc7 PF08317.11 KFH42549.1 - 0.002 17.1 157.7 0.019 13.9 19.3 8.0 2 2 3 7 7 7 4 Spc7 kinetochore protein GAS PF13851.6 KFH42549.1 - 0.0025 17.2 147.3 0.0071 15.7 16.9 9.7 3 2 5 9 9 9 6 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 KFH42549.1 - 0.0029 17.4 25.5 0.0039 17.0 12.3 10.9 4 2 7 11 11 10 3 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 KFH42549.1 - 0.0063 16.5 161.3 0.78 9.8 12.0 9.4 3 2 6 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KFH42549.1 - 0.016 15.8 191.1 0.042 14.4 4.1 11.4 2 1 8 11 11 10 0 Apg6 coiled-coil region Nup54_57_C PF18570.1 KFH42549.1 - 0.099 12.2 7.7 3.8 7.2 0.1 4.5 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain TPR_MLP1_2 PF07926.12 KFH42549.1 - 0.27 11.3 170.3 0.47 10.5 9.5 10.8 3 2 8 11 11 11 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KFH42549.1 - 3.4 7.7 140.7 0.036 14.2 16.9 8.3 3 2 5 8 8 8 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 KFH42549.1 - 9.8 5.7 143.6 0.033 13.8 14.2 8.0 1 1 4 6 6 5 0 Intermediate filament protein Methyltransf_2 PF00891.18 KFH42551.1 - 5.9e-16 58.4 0.0 5.9e-14 51.9 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KFH42551.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KFH42551.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 KFH42551.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DSHCT PF08148.12 KFH42552.1 - 3.7e-51 173.0 0.3 7.9e-51 172.0 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KFH42552.1 - 2.1e-39 134.4 0.1 1.4e-38 131.7 0.0 2.2 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KFH42552.1 - 1.1e-29 104.2 0.2 1.9e-29 103.4 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KFH42552.1 - 4.4e-18 65.7 0.2 1.7e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH42552.1 - 1.4e-06 28.6 0.0 6.2e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH42552.1 - 0.0001 22.3 0.2 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KFH42552.1 - 0.097 12.3 0.3 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein SWIRM PF04433.17 KFH42553.1 - 4.4e-15 55.8 0.0 7.1e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Zn_clus PF00172.18 KFH42554.1 - 0.0001 22.4 8.8 0.0002 21.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRAL_TRIO PF00650.20 KFH42555.1 - 5e-30 104.3 0.0 5.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFH42555.1 - 0.0086 16.2 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KFH42555.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) RRM_1 PF00076.22 KFH42556.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH42556.1 - 5.6e-05 22.9 0.0 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFH42556.1 - 0.00019 21.4 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFH42556.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Transket_pyr PF02779.24 KFH42557.1 - 5.1e-46 156.6 0.1 9.9e-46 155.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFH42557.1 - 8.4e-35 119.4 0.0 2.6e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF4478 PF14793.6 KFH42558.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Phospholip_A2_3 PF09056.11 KFH42560.1 - 1e-43 148.5 0.3 1.3e-43 148.1 0.3 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 RAC_head PF16717.5 KFH42561.1 - 2.6e-32 111.7 0.6 2.6e-32 111.7 0.6 3.4 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KFH42561.1 - 9.6e-21 73.7 1.2 3.6e-20 71.8 1.2 2.1 1 0 0 1 1 1 1 DnaJ domain NADH_u_ox_C PF12853.7 KFH42562.1 - 2.8e-27 94.5 0.1 4.5e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 KFH42562.1 - 2e-20 73.3 0.6 3.6e-20 72.4 0.3 1.5 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Fungal_trans PF04082.18 KFH42563.1 - 1.4e-09 37.4 0.1 2.5e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42563.1 - 2.9e-08 33.7 12.4 2.9e-08 33.7 12.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 KFH42564.1 - 1.2e-06 28.5 25.2 0.0001 22.3 25.2 2.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFH42564.1 - 0.0078 16.3 24.1 0.051 13.7 24.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor CENP_C_N PF15622.6 KFH42564.1 - 0.011 15.3 1.5 0.018 14.5 1.5 1.3 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal bZIP_Maf PF03131.17 KFH42564.1 - 0.13 12.8 14.1 0.26 11.9 14.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor RR_TM4-6 PF06459.12 KFH42564.1 - 6.3 6.5 7.4 11 5.8 7.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NYD-SP28_assoc PF14775.6 KFH42564.1 - 9.6 6.4 7.7 1.9 8.7 3.8 1.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF1691 PF07950.11 KFH42565.1 - 3e-38 130.8 4.9 4e-31 107.9 3.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Peptidase_M43 PF05572.13 KFH42567.1 - 1.5e-11 44.5 0.2 2.9e-11 43.5 0.2 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 KFH42567.1 - 0.08 12.6 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFH42567.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Matrixin MFS_1 PF07690.16 KFH42568.1 - 4.8e-29 101.4 22.5 4.8e-29 101.4 22.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KFH42569.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hemerythrin PF01814.23 KFH42569.1 - 0.04 14.5 2.9 0.1 13.3 2.9 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain SIKE PF05769.11 KFH42569.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 SIKE family zinc_ribbon_10 PF10058.9 KFH42570.1 - 1.4e-18 66.4 0.1 2.3e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TMEM174 PF15029.6 KFH42570.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 174 DUF3752 PF12572.8 KFH42570.1 - 0.35 11.4 8.0 0.49 10.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) HalOD2 PF18547.1 KFH42570.1 - 1.1 9.2 3.5 17 5.4 0.7 2.5 2 0 0 2 2 2 0 Halobacterial output domain 2 p450 PF00067.22 KFH42571.1 - 1.2e-48 166.1 0.0 2.3e-48 165.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Chordopox_A15 PF05846.12 KFH42571.1 - 0.11 12.8 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A15 protein Na_H_Exchanger PF00999.21 KFH42572.1 - 1.7e-54 185.1 43.3 2.4e-54 184.6 43.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Snf7 PF03357.21 KFH42573.1 - 1e-06 28.5 24.2 1.3e-06 28.1 23.9 1.4 1 1 0 1 1 1 1 Snf7 UPF0262 PF06793.12 KFH42573.1 - 0.0031 17.6 1.0 0.0051 16.9 1.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Ist1 PF03398.14 KFH42573.1 - 0.0077 16.2 6.9 0.014 15.3 6.9 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Fungal_trans PF04082.18 KFH42574.1 - 7.8e-19 67.7 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42574.1 - 5.2e-06 26.5 12.6 7.8e-06 25.9 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_Rg PF17915.1 KFH42574.1 - 0.59 9.6 5.3 1.1 8.7 5.3 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger Prot_inhib_II PF02428.15 KFH42574.1 - 1.7 9.1 6.7 2.8 8.5 0.2 2.3 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family LsmAD PF06741.13 KFH42575.1 - 8.8 7.0 8.9 32 5.2 8.9 1.9 1 0 0 1 1 1 0 LsmAD domain MFS_1 PF07690.16 KFH42576.1 - 3e-41 141.5 42.5 1.1e-35 123.2 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42576.1 - 4.2e-12 45.7 19.7 1.8e-11 43.6 19.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFH42576.1 - 6.4e-05 21.6 1.1 6.4e-05 21.6 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFH42576.1 - 0.00017 21.0 1.2 0.00017 21.0 1.2 2.4 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Myb_DNA-binding PF00249.31 KFH42577.1 - 1.4e-16 60.4 1.9 4.4e-10 39.6 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH42577.1 - 8.8e-10 38.7 0.9 5.7e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain ANAPC4_WD40 PF12894.7 KFH42578.1 - 0.015 15.6 0.1 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PTS_EIIB PF00367.20 KFH42578.1 - 0.082 12.4 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 phosphotransferase system, EIIB DUF3530 PF12048.8 KFH42578.1 - 0.98 8.8 4.2 0.56 9.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Myb_DNA-binding PF00249.31 KFH42579.1 - 0.00026 21.1 0.4 0.0075 16.4 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFH42579.1 - 0.11 12.8 0.3 0.81 10.0 0.0 2.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PX PF00787.24 KFH42580.1 - 5.6e-19 68.2 0.5 5.6e-19 68.2 0.5 2.0 2 0 0 2 2 2 1 PX domain Methylase_S PF01420.19 KFH42580.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain PAT1 PF09770.9 KFH42580.1 - 0.1 10.9 3.9 0.14 10.4 3.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NBP1 PF08537.10 KFH42580.1 - 0.28 10.6 8.3 2 7.8 1.3 2.3 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Spt20 PF12090.8 KFH42580.1 - 0.52 9.9 7.6 0.85 9.2 7.6 1.3 1 0 0 1 1 1 0 Spt20 family Sporozoite_P67 PF05642.11 KFH42580.1 - 2.2 6.3 12.0 3.2 5.7 12.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MmgE_PrpD PF03972.14 KFH42581.1 - 3.4e-130 434.5 3.3 3.9e-130 434.3 3.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_transf_15 PF01793.16 KFH42582.1 - 3e-96 322.5 8.6 1.1e-95 320.7 8.6 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase FAR1 PF03101.15 KFH42583.1 - 5.5e-06 27.0 0.1 9.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Sugarporin_N PF11471.8 KFH42583.1 - 0.00011 22.1 2.5 0.0016 18.3 0.1 2.8 2 1 1 3 3 3 1 Maltoporin periplasmic N-terminal extension AFT PF08731.11 KFH42583.1 - 0.0055 17.1 0.0 0.0083 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT Matrilin_ccoil PF10393.9 KFH42583.1 - 0.016 15.1 0.4 0.39 10.6 0.3 2.5 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ORF6C PF10552.9 KFH42583.1 - 0.063 13.4 0.1 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 ORF6C domain OmpH PF03938.14 KFH42583.1 - 0.064 13.6 0.3 17 5.8 0.0 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) XhlA PF10779.9 KFH42583.1 - 0.081 13.1 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Haemolysin XhlA Hemagglutinin PF00509.18 KFH42583.1 - 0.089 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin GAS PF13851.6 KFH42583.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 KFH42583.1 - 0.12 12.8 0.5 0.3 11.5 0.5 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Tropomyosin_1 PF12718.7 KFH42583.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Tropomyosin like YvrJ PF12841.7 KFH42583.1 - 0.15 11.6 0.8 0.52 9.9 0.4 2.0 2 0 0 2 2 2 0 YvrJ protein family HSBP1 PF06825.12 KFH42583.1 - 0.33 10.9 9.2 0.13 12.1 1.7 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Ribosomal_L34e PF01199.18 KFH42585.1 - 8.2e-44 147.9 2.9 1.1e-43 147.4 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KFH42585.1 - 0.75 9.8 5.8 1.7 8.7 0.3 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain COX5B PF01215.19 KFH42586.1 - 1e-57 193.4 0.0 1.4e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.10 KFH42586.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 KFH42587.1 - 0.0001 22.2 2.5 0.0001 22.2 2.5 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH42587.1 - 0.00055 19.8 4.6 0.0014 18.6 3.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH42587.1 - 0.0056 16.5 4.3 0.0068 16.2 0.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFH42587.1 - 0.085 12.7 5.1 0.25 11.2 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH42587.1 - 0.1 13.0 0.6 0.1 13.0 0.6 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 KFH42587.1 - 0.12 12.6 0.5 0.12 12.6 0.5 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFH42587.1 - 0.16 11.8 4.6 0.59 10.1 4.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH42587.1 - 0.2 11.5 3.8 0.1 12.5 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KFH42587.1 - 0.91 8.8 3.1 0.34 10.2 0.2 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 KFH42587.1 - 1.3 8.9 7.4 1 9.2 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SPX PF03105.19 KFH42587.1 - 5.9 6.7 8.5 7.7 6.3 8.5 1.3 1 0 0 1 1 1 0 SPX domain Abhydrolase_6 PF12697.7 KFH42588.1 - 1.4e-13 51.9 6.4 1.4e-13 51.9 6.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH42588.1 - 2e-13 50.6 0.0 1.4e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH42588.1 - 2.4e-11 43.4 0.0 6.8e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 KFH42588.1 - 5.2e-10 39.3 0.0 8.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFH42588.1 - 0.00029 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 KFH42588.1 - 0.00032 20.9 0.0 0.00071 19.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.27 KFH42588.1 - 0.00047 19.8 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.13 KFH42588.1 - 0.003 17.3 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 KFH42588.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KFH42588.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 KFH42588.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LCAT PF02450.15 KFH42588.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KFH42588.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_trans_4_4 PF13579.6 KFH42588.1 - 1.1 9.6 6.4 4.9 7.6 0.9 3.4 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain WD40 PF00400.32 KFH42589.1 - 3.8e-14 52.8 9.1 2.4e-06 28.1 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KFH42589.1 - 1.9e-13 50.4 0.0 5.2e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KFH42589.1 - 2.1e-07 31.2 0.7 0.0071 16.6 0.1 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BRCA-2_OB1 PF09103.10 KFH42589.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 OHCU_decarbox PF09349.10 KFH42590.1 - 5.5e-46 156.9 0.0 6.2e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF294 PF03445.13 KFH42590.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Myc_target_1 PF15179.6 KFH42591.1 - 0.0032 17.4 0.3 0.0044 17.0 0.3 1.1 1 0 0 1 1 1 1 Myc target protein 1 NICE-3 PF07406.11 KFH42591.1 - 0.17 11.8 0.1 0.21 11.5 0.1 1.1 1 0 0 1 1 1 0 NICE-3 protein Orthopox_A36R PF05950.11 KFH42591.1 - 0.21 11.7 0.0 0.28 11.3 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Lactonase PF10282.9 KFH42592.1 - 7.7e-57 193.1 0.0 1e-56 192.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KFH42592.1 - 0.012 14.2 0.0 0.71 8.3 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Prp19 PF08606.11 KFH42593.1 - 1.5e-31 108.2 1.6 3e-31 107.2 1.6 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KFH42593.1 - 1.4e-09 38.4 0.0 0.23 12.4 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH42593.1 - 1e-07 32.1 0.0 0.22 11.9 0.0 4.1 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 KFH42593.1 - 0.00075 19.3 0.0 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit V_ATPase_I_N PF18670.1 KFH42593.1 - 0.017 15.5 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Sun2_CC2 PF18580.1 KFH42593.1 - 0.031 14.5 0.3 1.2 9.4 0.1 3.1 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 TMP_2 PF06791.13 KFH42593.1 - 2.9 7.5 9.1 0.96 9.1 0.3 2.6 3 0 0 3 3 3 0 Prophage tail length tape measure protein Glyco_hydro_18 PF00704.28 KFH42595.1 - 0.00064 19.5 0.0 0.00064 19.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_16 PF00722.21 KFH42597.1 - 2.7e-46 157.3 0.8 3.6e-46 156.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KFH42597.1 - 0.034 14.6 12.6 0.034 14.6 12.6 2.0 2 0 0 2 2 2 0 Chitin recognition protein DUF5381 PF17353.2 KFH42597.1 - 0.19 11.5 0.0 5.7 6.7 0.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5381) Git3 PF11710.8 KFH42598.1 - 8.7e-19 68.1 5.2 8.7e-19 68.1 5.2 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KFH42598.1 - 4.4e-11 42.6 6.5 2.4e-10 40.2 7.1 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KFH42598.1 - 0.001 18.3 4.3 0.001 18.3 4.3 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KFH42598.1 - 0.0055 16.8 0.0 0.0055 16.8 0.0 2.5 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term ILVD_EDD PF00920.21 KFH42600.1 - 2.3e-205 683.1 0.8 2.7e-205 682.9 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.32 KFH42601.1 - 1e-23 83.1 6.3 1.1e-06 29.2 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFH42601.1 - 0.02 13.9 0.0 0.6 9.0 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L27A PF00828.19 KFH42603.1 - 3.9e-33 114.9 1.4 3.9e-33 114.9 1.4 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4604 PF15377.6 KFH42604.1 - 2.3e-29 103.1 9.8 2.6e-29 102.8 9.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF498 PF04430.14 KFH42605.1 - 1.2e-27 96.1 0.0 1.6e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) LPG_synthase_TM PF03706.13 KFH42607.1 - 0.0023 17.5 0.2 0.0029 17.2 0.2 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region MtrF PF09472.10 KFH42607.1 - 0.0082 15.5 0.3 0.016 14.6 0.3 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF4381 PF14316.6 KFH42607.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BatA PF07584.11 KFH42607.1 - 0.012 15.9 1.0 0.024 15.0 1.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal MFS_1 PF07690.16 KFH42607.1 - 0.043 12.7 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily FixQ PF05545.11 KFH42607.1 - 0.083 12.9 1.4 0.083 12.9 1.4 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Insulin_TMD PF17870.1 KFH42607.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment BatD PF13584.6 KFH42607.1 - 0.13 11.0 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF5305 PF17231.2 KFH42607.1 - 0.15 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 KFH42607.1 - 0.16 10.7 0.2 0.21 10.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KFH42607.1 - 0.16 12.9 0.1 0.29 12.1 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KFH42607.1 - 0.17 10.6 0.3 0.23 10.2 0.3 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NicO PF03824.16 KFH42607.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein EVC2_like PF12297.8 KFH42607.1 - 0.19 10.4 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein TT_ORF1 PF02956.14 KFH42607.1 - 0.21 10.2 13.8 0.3 9.7 13.8 1.2 1 0 0 1 1 1 0 TT viral orf 1 Amnionless PF14828.6 KFH42607.1 - 0.22 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless RCR PF12273.8 KFH42607.1 - 0.85 10.3 10.5 4.7 7.9 10.5 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red NCE101 PF11654.8 KFH42607.1 - 0.89 9.3 4.9 1 9.1 1.0 2.8 3 1 0 3 3 3 0 Non-classical export protein 1 Myc_target_1 PF15179.6 KFH42607.1 - 1.3 8.9 7.6 4.3 7.2 7.6 1.7 1 1 0 1 1 1 0 Myc target protein 1 LapA_dom PF06305.11 KFH42607.1 - 1.5 8.7 10.2 11 5.9 10.2 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4501 PF14946.6 KFH42607.1 - 5.3 7.1 5.2 0.55 10.3 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) HemY_N PF07219.13 KFH42607.1 - 5.6 7.2 6.3 16 5.7 6.3 1.8 1 1 0 1 1 1 0 HemY protein N-terminus Thioredoxin PF00085.20 KFH42608.1 - 3.3e-20 72.0 0.0 4.1e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFH42608.1 - 3.6e-07 29.8 0.0 4.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFH42608.1 - 0.0003 21.2 0.0 0.00081 19.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KFH42608.1 - 0.0091 15.8 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFH42608.1 - 0.06 13.5 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KFH42608.1 - 0.079 13.3 0.0 0.81 10.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KFH42608.1 - 0.098 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin eRF1_1 PF03463.15 KFH42609.1 - 1.5e-29 102.6 0.0 2.4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KFH42609.1 - 4.7e-19 69.0 0.0 7.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFH42609.1 - 5e-17 62.4 0.0 9.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 KFH42610.1 - 4.4e-39 134.4 0.0 7.2e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 KFH42610.1 - 0.028 14.3 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Development and cell death domain F-box-like PF12937.7 KFH42611.1 - 7.8e-05 22.5 0.0 0.00044 20.1 0.0 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFH42611.1 - 0.095 13.2 0.7 5.1 7.7 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) ADH_zinc_N PF00107.26 KFH42612.1 - 1.1e-13 51.3 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH42612.1 - 1.9e-07 30.9 0.2 2.1e-06 27.6 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH42612.1 - 0.0024 18.9 0.0 0.0044 18.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KFH42613.1 - 9.4e-16 58.2 0.0 2.2e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFH42613.1 - 0.042 13.3 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 4HBT_3 PF13622.6 KFH42614.1 - 8.3e-26 91.7 0.0 1.5e-25 90.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFH42614.1 - 9.2e-06 25.5 0.0 0.00065 19.5 0.0 2.9 2 1 0 2 2 2 1 Acyl-CoA thioesterase NAD_binding_10 PF13460.6 KFH42615.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFH42615.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Aldo_ket_red PF00248.21 KFH42616.1 - 1.5e-71 241.0 0.0 1.9e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRG8 PF17068.5 KFH42617.1 - 0.21 10.9 0.1 0.42 10.0 0.0 1.4 2 0 0 2 2 2 0 Required for respiratory growth protein 8 mitochondrial AAA PF00004.29 KFH42618.1 - 5.7e-19 68.8 0.0 1.1e-18 68.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH42618.1 - 0.0017 18.7 0.4 0.0066 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 KFH42618.1 - 0.0022 17.7 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KFH42618.1 - 0.0032 17.7 0.1 0.027 14.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH42618.1 - 0.024 14.8 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFH42618.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 KFH42618.1 - 0.2 10.6 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRN3 PF05327.11 KFH42618.1 - 6.7 5.1 5.8 10 4.5 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MUG113 PF13455.6 KFH42621.1 - 1.9e-23 82.9 0.0 3.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KFH42621.1 - 6.2e-23 81.3 0.0 1.5e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF4083 PF13314.6 KFH42622.1 - 5 7.1 7.0 3.3 7.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Sugar_tr PF00083.24 KFH42623.1 - 8.6e-111 371.0 16.8 9.9e-111 370.8 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42623.1 - 2e-33 115.8 27.9 2.5e-32 112.2 20.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH42623.1 - 0.0029 16.1 0.7 0.0043 15.5 0.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 KFH42624.1 - 9.6e-29 101.0 23.3 1.4e-28 100.4 23.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFH42624.1 - 4.7e-09 36.3 0.0 9.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CopK PF11525.8 KFH42624.1 - 0.17 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein K Actin PF00022.19 KFH42625.1 - 1.2e-97 327.1 0.0 1.1e-96 324.0 0.0 1.9 1 1 0 1 1 1 1 Actin DUF5579 PF17742.1 KFH42625.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Cerato-platanin PF07249.12 KFH42628.1 - 9.4e-06 25.7 0.2 1.6e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Cerato-platanin HGWP PF03578.15 KFH42630.1 - 0.094 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 HGWP repeat Ferritin_2 PF13668.6 KFH42631.1 - 1.7e-14 54.2 0.0 2.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_16 PF00722.21 KFH42632.1 - 5.2e-18 65.1 0.2 7.9e-18 64.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KFH42632.1 - 4.8e-08 31.8 0.0 0.0054 15.2 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) ILVD_EDD PF00920.21 KFH42633.1 - 1.8e-214 713.1 0.0 2.2e-214 712.9 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KFH42633.1 - 0.15 12.3 0.0 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain ArsB PF02040.15 KFH42636.1 - 2.4e-08 33.7 4.4 5.5e-08 32.6 1.6 2.3 2 0 0 2 2 2 1 Arsenical pump membrane protein DUF89 PF01937.19 KFH42637.1 - 3.1e-131 437.5 0.1 3.6e-131 437.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acyltransferase PF01553.21 KFH42638.1 - 1.4e-06 28.0 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase COesterase PF00135.28 KFH42639.1 - 4.5e-82 276.5 0.0 1.2e-74 252.0 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH42639.1 - 3.7e-11 43.3 0.4 2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH42639.1 - 0.42 10.1 1.0 0.69 9.3 0.1 1.9 2 1 0 2 2 2 0 Prolyl oligopeptidase family Exo_endo_phos PF03372.23 KFH42640.1 - 4.4e-09 36.2 0.0 3.5e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFH42640.1 - 0.00025 20.8 0.2 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase He_PIG PF05345.12 KFH42640.1 - 0.0017 18.5 3.1 0.0045 17.1 3.1 1.8 1 0 0 1 1 1 1 Putative Ig domain Big_2 PF02368.18 KFH42640.1 - 0.37 10.7 5.5 0.35 10.8 2.9 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) RAI16-like PF10257.9 KFH42641.1 - 1.4e-72 244.6 0.5 2.3e-72 243.9 0.5 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma70_ner PF04546.13 KFH42641.1 - 3.4 7.5 14.5 0.14 12.1 0.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Period_C PF12114.8 KFH42643.1 - 0.0012 18.5 0.1 0.0033 17.0 0.1 1.7 1 0 0 1 1 1 1 Period protein 2/3C-terminal region HalX PF08663.10 KFH42643.1 - 0.05 13.9 7.2 5.2 7.5 0.2 3.5 3 0 0 3 3 3 0 HalX domain DUF1700 PF08006.11 KFH42643.1 - 0.51 9.9 1.1 0.97 8.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) AltA1 PF16541.5 KFH42644.1 - 2.1e-10 41.4 0.0 2.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 PGAP1 PF07819.13 KFH42645.1 - 0.00067 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFH42645.1 - 0.0013 19.3 0.7 0.0042 17.7 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFH42645.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 KFH42645.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KFH42645.1 - 0.068 12.4 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NPAT_C PF15712.5 KFH42645.1 - 0.13 10.8 0.4 0.19 10.3 0.4 1.1 1 0 0 1 1 1 0 NPAT C terminus Kinesin PF00225.23 KFH42646.1 - 9.8e-106 353.4 1.4 9.8e-106 353.4 1.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFH42646.1 - 1.9e-56 190.2 0.1 6e-56 188.5 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KFH42646.1 - 0.033 12.9 43.5 0.0044 15.8 37.7 2.1 2 1 0 2 2 2 0 Weak chloroplast movement under blue light AAA_16 PF13191.6 KFH42646.1 - 0.034 14.5 0.0 0.034 14.5 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 KFH42646.1 - 3.4 5.0 42.3 8.3 3.8 42.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.6 KFH42646.1 - 5.1 7.4 7.8 0.85 9.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain EcKinase PF02958.20 KFH42647.1 - 6.9e-10 38.7 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KFH42647.1 - 2.4e-08 34.2 1.8 4e-08 33.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH42647.1 - 0.0092 15.6 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Na_Ca_ex PF01699.24 KFH42648.1 - 8.3e-24 84.3 29.5 3.5e-14 53.0 10.4 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1847 PF08901.11 KFH42648.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF872 PF05915.12 KFH42648.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.4 4 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Mannosyl_trans3 PF11051.8 KFH42649.1 - 1.6e-31 109.7 0.0 9.6e-31 107.1 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_hydro_61 PF03443.14 KFH42650.1 - 1.8e-59 201.1 0.2 2.2e-59 200.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DNA_pol_A_exo1 PF01612.20 KFH42651.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease Sod_Fe_C PF02777.18 KFH42652.1 - 1.8e-35 121.2 0.2 4e-35 120.1 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFH42652.1 - 1.5e-33 115.1 8.5 3.7e-33 113.9 1.3 2.9 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, alpha-hairpin domain LIM PF00412.22 KFH42654.1 - 7e-24 83.8 25.7 2.3e-08 34.1 6.7 3.7 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 KFH42654.1 - 0.0087 15.7 0.3 0.0087 15.7 0.3 2.8 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 KFH42654.1 - 0.23 11.4 14.2 4.7 7.2 1.2 5.6 5 0 0 5 5 5 0 Nudix N-terminal DZR PF12773.7 KFH42654.1 - 2.4 8.3 25.9 11 6.1 10.7 4.2 1 1 2 3 3 3 0 Double zinc ribbon Nup84_Nup100 PF04121.13 KFH42655.1 - 3.3e-179 597.5 0.0 4.2e-179 597.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TNFR_16_TM PF18422.1 KFH42655.1 - 0.076 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Mad3_BUB1_I PF08311.12 KFH42656.1 - 1.6e-44 150.8 0.1 6.8e-44 148.8 0.2 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFH42656.1 - 1.1e-08 34.8 0.0 6.8e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KFH42656.1 - 1.3e-08 34.8 0.0 8.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 KFH42656.1 - 0.00042 20.4 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 KFH42656.1 - 0.001 18.4 0.0 0.0046 16.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PI3K_1B_p101 PF10486.9 KFH42656.1 - 7.6 4.2 5.5 11 3.6 5.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Fungal_trans PF04082.18 KFH42657.1 - 1.2e-13 50.7 0.1 2.3e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42657.1 - 1.5e-07 31.4 11.1 2.5e-07 30.7 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_M PF01031.20 KFH42659.1 - 2.2e-111 371.7 0.0 4e-111 370.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFH42659.1 - 2.5e-57 193.6 0.0 5.8e-57 192.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFH42659.1 - 1.5e-30 105.2 1.5 8.2e-30 102.8 2.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFH42659.1 - 0.00016 21.8 0.3 0.0013 18.8 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ank_5 PF13857.6 KFH42661.1 - 1.7e-34 117.4 0.2 5.4e-10 39.3 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH42661.1 - 1.3e-33 115.4 0.0 4.2e-14 52.9 0.1 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH42661.1 - 6e-31 103.0 0.1 0.00042 20.5 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFH42661.1 - 2.1e-29 101.5 5.7 1e-09 38.7 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFH42661.1 - 5.5e-28 96.2 0.4 6.2e-05 23.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat SH3_9 PF14604.6 KFH42662.1 - 4.5e-25 87.3 2.5 5e-12 45.5 0.3 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFH42662.1 - 4.3e-21 74.3 4.8 3.8e-12 45.6 0.3 3.5 3 0 0 3 3 3 2 SH3 domain Cofilin_ADF PF00241.20 KFH42662.1 - 1e-17 64.1 0.0 1.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KFH42662.1 - 1.9e-16 59.5 0.1 1.7e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain AOX PF01786.17 KFH42664.1 - 2.6e-91 305.0 0.2 3.1e-91 304.8 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase MDM31_MDM32 PF08118.11 KFH42665.1 - 1.2e-249 829.3 0.1 1.2e-249 829.3 0.1 1.4 2 0 0 2 2 2 1 Yeast mitochondrial distribution and morphology (MDM) proteins 4HBT PF03061.22 KFH42666.1 - 2.1e-11 44.0 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AP_endonuc_2 PF01261.24 KFH42667.1 - 2.4e-29 102.3 0.2 3.6e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel V-ATPase_C PF03223.15 KFH42668.1 - 6.3e-120 401.0 0.1 7.2e-120 400.8 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 KFH42668.1 - 0.0027 18.3 0.3 0.008 16.8 0.1 1.9 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Prefoldin PF02996.17 KFH42669.1 - 7e-28 97.0 1.1 9.1e-28 96.6 1.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFH42669.1 - 0.0019 18.1 5.8 0.09 12.7 0.7 2.1 2 0 0 2 2 2 2 Prefoldin subunit AIP3 PF03915.13 KFH42669.1 - 0.0051 16.0 2.3 0.0068 15.6 2.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Fib_alpha PF08702.10 KFH42669.1 - 0.007 16.6 1.9 1 9.5 0.2 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Sec2p PF06428.11 KFH42669.1 - 0.02 14.8 4.5 2.6 8.1 1.2 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CLZ PF16526.5 KFH42669.1 - 0.037 14.4 5.2 0.66 10.4 0.7 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 KFH42669.1 - 0.06 13.1 8.2 1.1 9.0 0.5 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UvsW PF11637.8 KFH42669.1 - 0.061 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW E2F_CC-MB PF16421.5 KFH42669.1 - 0.23 11.9 3.2 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF1664 PF07889.12 KFH42669.1 - 0.44 10.6 4.1 0.94 9.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KFH42669.1 - 0.7 10.1 7.2 4.3 7.5 0.9 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prominin PF05478.11 KFH42669.1 - 0.95 7.3 5.0 2.1 6.2 5.0 1.6 1 1 0 1 1 1 0 Prominin CC2-LZ PF16516.5 KFH42669.1 - 1.3 9.4 7.6 6.5 7.2 1.7 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc24 PF08286.11 KFH42669.1 - 1.6 9.0 5.8 8.2 6.7 0.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 betaPIX_CC PF16523.5 KFH42669.1 - 2.8 7.8 7.0 1.3 8.8 2.5 2.4 1 1 1 2 2 2 0 betaPIX coiled coil CBF PF03914.17 KFH42670.1 - 1.4e-52 178.1 0.6 1e-51 175.4 0.0 2.6 2 0 0 2 2 2 1 CBF/Mak21 family BUD22 PF09073.10 KFH42670.1 - 3.6 6.8 56.6 1.2 8.4 24.4 2.3 2 0 0 2 2 2 0 BUD22 Rad60-SLD PF11976.8 KFH42671.1 - 1.2e-19 69.8 0.1 1.5e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFH42671.1 - 7.2e-10 38.5 0.1 8.2e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family AAA PF00004.29 KFH42672.1 - 7.9e-17 61.9 0.0 1.4e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KFH42672.1 - 2e-11 43.9 0.1 8.4e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 KFH42672.1 - 5.9e-11 43.0 0.0 3.8e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFH42672.1 - 7.3e-08 32.8 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 KFH42672.1 - 5.6e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.6 KFH42672.1 - 0.0057 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFH42672.1 - 0.0099 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KFH42672.1 - 0.021 14.7 0.0 0.39 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KFH42672.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH42672.1 - 0.058 13.9 0.0 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFH42672.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KFH42672.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.13 KFH42673.1 - 6.2e-34 117.2 0.3 6.2e-34 117.2 0.3 2.0 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DUF3801 PF12687.7 KFH42673.1 - 0.019 15.1 2.8 0.032 14.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Ndc1_Nup PF09531.10 KFH42673.1 - 0.094 11.4 8.4 0.1 11.2 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 KFH42673.1 - 0.62 11.1 2.7 1.5 9.9 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Jnk-SapK_ap_N PF09744.9 KFH42673.1 - 7.2 6.8 12.4 1.2 9.4 3.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 F-box PF00646.33 KFH42674.1 - 1.7e-05 24.6 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFH42674.1 - 0.00072 19.4 0.1 0.00072 19.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like CHCH PF06747.13 KFH42676.1 - 8.3e-05 22.6 1.9 0.00019 21.5 1.9 1.6 1 1 1 2 2 2 2 CHCH domain COX17 PF05051.13 KFH42676.1 - 0.0084 16.4 3.9 0.28 11.5 0.5 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KFH42676.1 - 0.021 15.1 3.8 0.27 11.5 4.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KFH42676.1 - 0.18 11.8 0.8 0.26 11.3 0.8 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KFH42676.1 - 0.31 11.3 1.9 12 6.3 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) TMF_TATA_bd PF12325.8 KFH42677.1 - 2.1e-39 134.3 7.4 2.1e-39 134.3 7.4 6.6 3 2 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFH42677.1 - 9.3e-19 67.2 11.2 9.3e-19 67.2 11.2 8.6 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.6 KFH42677.1 - 0.0018 17.8 12.4 0.0018 17.8 12.4 5.7 3 2 1 5 5 5 2 Domain of unknown function (DUF4618) EzrA PF06160.12 KFH42677.1 - 0.0039 15.4 65.0 0.045 11.9 54.3 2.5 2 1 0 2 2 2 2 Septation ring formation regulator, EzrA ATG16 PF08614.11 KFH42677.1 - 0.0044 17.3 4.2 0.0044 17.3 4.2 6.6 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KFH42677.1 - 0.6 10.6 23.9 3.4 8.2 0.3 6.6 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KFH42677.1 - 0.66 9.3 91.3 0.0083 15.5 14.9 5.4 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KFH42677.1 - 1.2 9.2 27.4 11 6.1 0.0 6.9 4 1 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 KFH42678.1 - 5e-45 150.6 15.7 1.2e-08 35.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 KFH42678.1 - 0.046 12.4 1.6 11 4.5 0.0 3.8 1 1 3 5 5 5 0 Nucleoporin Nup120/160 Menin PF05053.13 KFH42678.1 - 2.7 6.2 7.4 3.5 5.9 7.4 1.1 1 0 0 1 1 1 0 Menin Glutaredoxin PF00462.24 KFH42679.1 - 3.3e-17 62.5 0.0 2.9e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KFH42679.1 - 1.8e-13 50.4 0.0 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFH42679.1 - 0.044 14.1 0.0 5.9 7.3 0.0 2.5 2 1 1 3 3 3 0 Thioredoxin-like HyaE PF07449.11 KFH42679.1 - 0.14 12.2 0.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFH42679.1 - 0.14 12.6 0.0 1.7 9.1 0.0 2.6 2 2 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFH42679.1 - 0.18 11.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain F-box PF00646.33 KFH42680.1 - 1.4e-08 34.4 0.4 3.5e-08 33.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFH42680.1 - 6.1e-06 26.0 0.2 6.1e-06 26.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like KH_8 PF17903.1 KFH42681.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFH42681.1 - 0.0085 15.9 0.4 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 KH domain APS_kinase PF01583.20 KFH42682.1 - 1.7e-71 239.2 0.0 2.4e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KFH42682.1 - 9.7e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH42682.1 - 1.9e-05 25.2 0.0 3.1e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFH42682.1 - 0.00048 19.7 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KFH42682.1 - 0.007 16.8 0.1 0.012 16.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KFH42682.1 - 0.022 14.1 0.0 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin CPT PF07931.12 KFH42682.1 - 0.033 14.0 0.2 0.14 12.0 0.2 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.18 KFH42682.1 - 0.036 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PRK PF00485.18 KFH42682.1 - 0.036 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 KFH42682.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFH42682.1 - 0.077 12.1 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF463 PF04317.12 KFH42682.1 - 0.094 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Dicty_REP PF05086.12 KFH42683.1 - 0.91 7.4 3.9 1.5 6.7 3.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KFH42683.1 - 6.6 6.7 12.5 0.38 10.7 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) eIF3_subunit PF08597.10 KFH42684.1 - 5.2e-75 252.5 19.5 5.8e-75 252.3 19.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4423 PF14394.6 KFH42684.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) PRP4 PF08799.11 KFH42684.1 - 0.76 9.4 5.3 1.7 8.2 5.3 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like tRNA-synt_2b PF00587.25 KFH42685.1 - 2.7e-31 108.9 0.0 4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFH42685.1 - 1.5e-12 47.5 0.0 3.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain zf-C2H2 PF00096.26 KFH42686.1 - 2.3e-13 49.8 12.5 3.5e-06 27.2 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH42686.1 - 8e-13 48.2 7.9 1.8e-07 31.3 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH42686.1 - 7e-09 35.8 11.5 0.00039 21.0 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH42686.1 - 2.8e-08 33.5 5.4 0.00031 20.6 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH42686.1 - 1.1e-06 28.7 1.3 0.085 13.2 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH42686.1 - 0.00049 20.4 5.7 0.013 15.9 0.2 3.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFH42686.1 - 0.0067 16.2 5.4 0.4 10.5 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KFH42686.1 - 0.069 13.5 1.4 0.13 12.6 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KFH42686.1 - 0.086 13.4 0.8 0.23 12.0 0.8 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KFH42686.1 - 0.29 11.6 2.4 9.1 6.8 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KFH42686.1 - 0.35 11.1 3.6 14 6.0 0.1 2.5 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KFH42686.1 - 2.6 8.3 5.5 5 7.3 5.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-PARP PF00645.18 KFH42689.1 - 1.3e-22 80.4 0.1 5.3e-22 78.5 0.1 2.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region 4HBT_3 PF13622.6 KFH42690.1 - 7.4e-80 268.8 4.0 8.8e-80 268.5 4.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFH42690.1 - 4.8e-24 84.7 0.0 4.9e-10 39.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Putative_PNPOx PF01243.20 KFH42691.1 - 4.2e-11 42.9 0.0 8.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KFH42691.1 - 0.0031 17.5 0.1 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pirin PF02678.16 KFH42692.1 - 1.1e-23 83.2 0.3 2.4e-22 79.0 0.3 2.3 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KFH42692.1 - 0.0076 15.9 1.9 0.67 9.7 0.2 3.1 2 1 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.6 KFH42692.1 - 0.009 15.7 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 1 AraC-binding-like domain Pkinase PF00069.25 KFH42693.1 - 1.9e-53 181.5 0.0 6.8e-51 173.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42693.1 - 1.2e-32 113.3 0.0 6.8e-32 110.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KFH42693.1 - 0.00044 19.4 0.1 0.00088 18.4 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KFH42693.1 - 0.00051 19.4 0.0 0.00075 18.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFH42693.1 - 0.0084 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFH42693.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MoaE PF02391.17 KFH42694.1 - 1.5e-39 134.8 0.1 1.9e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Lipase_GDSL_lke PF16255.5 KFH42694.1 - 0.04 13.3 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase BPL_LplA_LipB PF03099.19 KFH42695.1 - 5.6e-05 23.1 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.23 KFH42696.1 - 2e-59 201.6 0.1 4e-59 200.6 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH42696.1 - 6.2e-10 39.6 0.2 3.5e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFH42696.1 - 0.0027 18.3 0.4 2.8 8.6 0.0 3.5 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KFH42696.1 - 0.0098 16.4 0.3 0.22 12.1 0.0 3.0 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease DUF3433 PF11915.8 KFH42697.1 - 1.1e-23 83.5 30.2 8.2e-23 80.7 1.5 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF4381 PF14316.6 KFH42697.1 - 0.045 14.0 3.6 4.1 7.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CPSase_L_D2 PF02786.17 KFH42699.1 - 4.6e-72 241.9 0.0 8e-72 241.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFH42699.1 - 1.9e-36 125.0 0.1 4.8e-36 123.7 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFH42699.1 - 4.1e-36 123.3 0.0 8.5e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFH42699.1 - 1.1e-16 60.4 1.3 3.9e-16 58.6 1.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFH42699.1 - 3.2e-09 36.5 0.0 0.0032 17.3 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KFH42699.1 - 1.2e-07 31.5 0.0 2.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFH42699.1 - 3.8e-07 29.9 0.0 1.8e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KFH42699.1 - 2.6e-05 24.9 0.2 0.47 11.2 0.0 3.6 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KFH42699.1 - 0.00012 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KFH42699.1 - 0.0031 16.8 0.2 1.5 8.0 0.0 2.9 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion CoA_binding_2 PF13380.6 KFH42699.1 - 0.016 15.7 0.2 14 6.3 0.1 3.7 2 2 0 2 2 2 0 CoA binding domain GCV_H PF01597.19 KFH42699.1 - 0.09 12.7 0.2 0.31 10.9 0.2 1.9 1 0 0 1 1 1 0 Glycine cleavage H-protein 5_3_exonuc PF01367.20 KFH42700.1 - 0.28 11.8 0.9 3.4 8.3 0.6 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold p450 PF00067.22 KFH42702.1 - 2.3e-71 241.0 0.0 2.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PI3_PI4_kinase PF00454.27 KFH42704.1 - 3.5e-47 161.3 0.0 6.1e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFH42704.1 - 1.3e-33 116.7 4.3 2.4e-33 115.8 4.3 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KFH42704.1 - 7.2e-33 112.5 0.1 2.2e-30 104.6 0.0 3.4 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 KFH42704.1 - 1.7e-15 56.5 0.0 4.7e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 KFH42704.1 - 0.099 13.2 6.8 0.47 11.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GDI PF00996.18 KFH42705.1 - 6.2e-22 77.7 0.0 6.9e-21 74.3 0.0 2.3 1 1 0 1 1 1 1 GDP dissociation inhibitor DUF5518 PF17647.1 KFH42705.1 - 0.028 14.6 3.3 0.054 13.6 3.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Rad21_Rec8_N PF04825.13 KFH42706.1 - 1.3e-33 115.4 0.0 2.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein RGS12_us1 PF16613.5 KFH42706.1 - 4.5 7.6 7.9 0.32 11.3 2.2 1.9 2 0 0 2 2 2 0 Unstructured region of RGS12 Fungal_trans PF04082.18 KFH42708.1 - 2e-08 33.6 0.0 4.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42708.1 - 0.01 15.9 5.7 0.022 14.9 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KFH42709.1 - 8.2e-10 37.5 0.0 4.5e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein GGACT PF06094.12 KFH42710.1 - 3.7e-09 37.2 0.1 5.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KFH42710.1 - 5.4e-05 23.5 0.0 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family MAGI_u5 PF16666.5 KFH42710.1 - 0.34 11.1 6.5 0.83 9.8 6.5 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI Oxysterol_BP PF01237.18 KFH42711.1 - 4e-134 447.2 0.2 1.7e-132 441.8 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 KFH42711.1 - 3e-14 53.3 0.0 1.2e-09 38.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH42711.1 - 9.3e-14 50.2 0.2 5.3e-05 23.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFH42711.1 - 1.9e-13 50.2 0.5 5.2e-05 23.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFH42711.1 - 2.7e-13 49.9 0.1 2e-07 31.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFH42711.1 - 9.4e-13 48.4 0.0 2.1e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KFH42711.1 - 2.1e-12 47.5 1.3 3.9e-12 46.6 1.3 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFH42711.1 - 1.3e-07 31.8 0.7 2.9e-07 30.7 0.7 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFH42711.1 - 7.2e-05 23.2 4.5 0.00015 22.2 3.9 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PTN13_u3 PF16599.5 KFH42711.1 - 0.0084 16.2 4.2 0.0084 16.2 4.2 2.6 2 0 0 2 2 2 1 Unstructured linker region on PTN13 protein between PDZ PH_17 PF18012.1 KFH42711.1 - 0.024 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 PH domain CMAS PF02353.20 KFH42712.1 - 4.1e-56 190.3 0.1 5.1e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFH42712.1 - 5.9e-09 36.5 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH42712.1 - 7.3e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH42712.1 - 1.1e-08 35.6 0.1 3.2e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 KFH42712.1 - 4.7e-05 23.0 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFH42712.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH42712.1 - 0.0014 19.4 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH42712.1 - 0.0055 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFH42712.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KFH42712.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFH42712.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2304 PF10066.9 KFH42712.1 - 0.5 10.6 4.1 1 9.6 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Mem_trans PF03547.18 KFH42713.1 - 3.1e-53 180.6 0.0 4.8e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein TrbL PF04610.14 KFH42713.1 - 0.017 14.9 3.5 0.02 14.6 2.2 1.8 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MobB PF03205.14 KFH42713.1 - 0.04 13.8 0.4 0.073 13.0 0.4 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-patch PF01585.23 KFH42714.1 - 1.1e-10 41.2 2.4 2.3e-10 40.2 2.4 1.6 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KFH42714.1 - 9.2e-06 24.9 3.1 2.1e-05 23.7 3.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KFH42714.1 - 1.4e-05 25.1 3.5 5.1e-05 23.3 3.5 2.0 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFH42714.1 - 6.6e-05 22.7 0.1 0.042 13.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.13 KFH42714.1 - 0.015 14.9 1.2 0.015 14.9 1.2 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 KFH42714.1 - 0.037 14.4 0.4 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFH42714.1 - 0.95 9.8 2.2 0.81 10.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SUR7 PF06687.12 KFH42715.1 - 1e-30 106.9 5.1 1.2e-30 106.7 5.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family ALO PF04030.14 KFH42718.1 - 5.4e-82 275.5 0.0 7.5e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KFH42718.1 - 4e-28 97.9 0.1 5.6e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Ferric_reduct PF01794.19 KFH42719.1 - 1.3e-19 70.5 3.6 1.3e-19 70.5 3.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH42719.1 - 2.5e-13 50.4 0.0 7.1e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH42719.1 - 5.6e-13 48.9 0.1 2.1e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KFH42719.1 - 0.00046 20.8 0.0 0.053 14.2 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 KFH42719.1 - 0.55 10.8 6.3 0.17 12.5 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) TRI5 PF06330.11 KFH42720.1 - 1.4e-23 83.4 0.0 1.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SSF PF00474.17 KFH42721.1 - 2.7e-21 75.9 27.7 2.7e-21 75.9 27.7 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family RNase_PH PF01138.21 KFH42722.1 - 9.3e-19 68.2 0.0 2.7e-18 66.8 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFH42722.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rad21_Rec8 PF04824.16 KFH42723.1 - 1.4e-06 27.5 0.0 2.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein HPTransfase PF10090.9 KFH42723.1 - 0.07 12.9 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain SMC_ScpA PF02616.14 KFH42723.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Amidoligase_2 PF12224.8 KFH42724.1 - 7.1e-14 52.1 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Aminotran_1_2 PF00155.21 KFH42725.1 - 3.8e-47 161.2 0.0 4.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFH42725.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3802 PF12290.8 KFH42726.1 - 0.0071 16.8 1.5 3.3 8.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3802) ATG16 PF08614.11 KFH42726.1 - 0.013 15.7 21.0 0.024 14.9 21.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 KFH42726.1 - 0.03 14.4 22.7 0.07 13.2 22.5 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KFH42726.1 - 0.18 12.2 17.6 0.38 11.1 17.6 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF812 PF05667.11 KFH42726.1 - 0.37 9.6 14.4 0.5 9.2 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KELK PF15796.5 KFH42726.1 - 0.54 10.8 15.7 0.08 13.4 11.3 1.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 KFH42726.1 - 0.66 9.3 12.1 1.1 8.6 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5320 PF17253.2 KFH42726.1 - 0.69 11.0 4.0 2 9.5 4.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Golgin_A5 PF09787.9 KFH42726.1 - 1.6 8.2 17.8 2.5 7.5 17.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4172 PF13776.6 KFH42726.1 - 1.6 9.1 4.8 1.4 9.3 0.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) Exonuc_VII_L PF02601.15 KFH42726.1 - 1.6 8.2 10.1 2.5 7.6 10.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KFH42726.1 - 2.9 7.1 6.4 4.4 6.5 6.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 KFH42726.1 - 3.4 6.9 10.1 5.1 6.4 10.1 1.2 1 0 0 1 1 1 0 FAM76 protein FapA PF03961.13 KFH42726.1 - 3.5 6.1 7.3 4.7 5.7 7.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KFH42726.1 - 4.7 6.0 22.9 2.6 6.9 20.9 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KFH42726.1 - 6.7 5.7 16.4 13 4.8 16.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 KFH42726.1 - 7.4 5.4 9.2 10 4.9 9.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_GPO PF05929.11 KFH42726.1 - 7.6 6.1 13.3 13 5.3 13.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CDH-cyt PF16010.5 KFH42728.1 - 1.2e-54 184.8 0.1 3.7e-54 183.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KFH42728.1 - 2.1e-26 93.0 0.1 6.9e-26 91.3 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH42728.1 - 5.1e-25 88.7 0.0 8e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFH42728.1 - 5.3e-09 35.7 0.7 0.00014 21.0 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH42728.1 - 4.4e-05 23.6 0.2 0.00028 21.1 0.0 2.6 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFH42728.1 - 0.00018 20.7 0.2 0.00043 19.4 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KFH42728.1 - 0.0002 20.2 0.0 0.00051 18.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KFH42728.1 - 0.00023 20.9 3.6 0.0022 17.6 3.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH42728.1 - 0.00033 20.1 0.2 0.017 14.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH42728.1 - 0.00074 18.8 0.2 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH42728.1 - 0.00093 18.5 0.2 0.0099 15.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH42728.1 - 0.001 19.6 0.1 0.21 12.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH42728.1 - 0.0092 15.3 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KFH42728.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KFH42728.1 - 0.12 11.4 0.5 0.68 8.9 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2048 PF09752.9 KFH42728.1 - 0.19 10.8 0.1 0.32 10.1 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Adaptin_N PF01602.20 KFH42729.1 - 1.9e-114 383.1 1.2 2.6e-114 382.7 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFH42729.1 - 5.3e-56 189.0 3.6 1.1e-55 187.9 3.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFH42729.1 - 4.4e-36 123.5 0.2 1.4e-35 121.9 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFH42729.1 - 1.8e-16 60.3 2.3 3.2e-11 43.5 0.0 5.3 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KFH42729.1 - 1.5e-07 31.6 8.2 0.051 13.6 0.1 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFH42729.1 - 0.0026 17.4 3.6 0.0093 15.5 0.2 3.0 3 1 1 4 4 4 1 CLASP N terminal Alpha_adaptin_C PF02296.16 KFH42729.1 - 0.05 13.8 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 KFH42729.1 - 0.067 13.9 0.0 73 4.5 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Coatomer_b_Cpla PF14806.6 KFH42729.1 - 0.083 12.9 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform DUF5010 PF16402.5 KFH42729.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) RTP1_C1 PF10363.9 KFH42729.1 - 0.16 12.2 0.2 5.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KFH42729.1 - 0.34 11.3 8.8 1.2 9.5 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Spc24 PF08286.11 KFH42730.1 - 8.8e-38 128.8 1.0 3.1e-36 123.8 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4164 PF13747.6 KFH42730.1 - 0.023 14.9 10.2 0.047 14.0 6.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Troponin PF00992.20 KFH42730.1 - 0.024 14.9 0.8 0.051 13.9 0.8 1.5 1 1 0 1 1 1 0 Troponin Vps5 PF09325.10 KFH42730.1 - 0.069 12.7 1.9 0.099 12.2 1.9 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Nsp1_C PF05064.13 KFH42730.1 - 0.43 10.4 3.9 13 5.6 0.1 2.9 3 0 0 3 3 3 0 Nsp1-like C-terminal region FUSC PF04632.12 KFH42730.1 - 0.97 7.9 6.0 1.1 7.7 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMP-binding PF00501.28 KFH42732.1 - 6.2e-78 262.3 0.0 8e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH42732.1 - 3.4e-14 53.6 0.6 9.5e-14 52.1 0.6 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KFH42733.1 - 4.1e-23 81.8 0.7 5.8e-23 81.3 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH42733.1 - 3e-08 33.6 9.1 5.2e-08 32.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP12 PF07542.11 KFH42734.1 - 8e-42 142.4 0.1 1.7e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein UnbV_ASPIC PF07593.12 KFH42734.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV RRM_1 PF00076.22 KFH42735.1 - 1.5e-20 72.8 0.0 4.4e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH42735.1 - 0.0016 18.3 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Smg4_UPF3 PF03467.15 KFH42735.1 - 0.0034 17.4 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF1917 PF08939.10 KFH42735.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) TatD_DNase PF01026.21 KFH42736.1 - 2.6e-32 112.2 0.0 4.3e-32 111.5 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase Ntox22 PF15527.6 KFH42736.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 22 Lactamase_B_2 PF12706.7 KFH42737.1 - 5.1e-09 35.9 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KFH42737.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KFH42737.1 - 0.0011 19.1 0.0 0.0086 16.1 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_MLP1_2 PF07926.12 KFH42738.1 - 9.2e-42 142.2 49.8 9e-40 135.7 30.8 19.0 9 5 9 18 18 18 4 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KFH42738.1 - 0.0022 17.3 4.3 0.0022 17.3 4.3 19.3 7 4 15 23 23 23 2 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFH42738.1 - 0.0037 17.5 14.8 0.0037 17.5 14.8 16.9 5 3 11 16 16 16 3 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KFH42738.1 - 0.021 15.0 0.8 0.021 15.0 0.8 23.7 18 9 8 27 27 27 0 JNK-interacting protein leucine zipper II zf-C6H2 PF15801.5 KFH42739.1 - 8.9e-08 32.3 7.9 0.00022 21.5 0.8 2.5 2 0 0 2 2 2 2 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFH42739.1 - 6.3e-06 26.2 11.6 0.0023 18.0 1.0 2.7 2 0 0 2 2 2 2 MYND finger DUF5363 PF17320.2 KFH42739.1 - 0.0013 18.5 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5363) Prok-RING_4 PF14447.6 KFH42739.1 - 0.77 9.7 7.0 3.4 7.6 0.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SQS_PSY PF00494.19 KFH42740.1 - 1.2e-62 211.8 0.2 2e-62 211.1 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Rap1_C PF11626.8 KFH42740.1 - 0.045 13.8 0.0 6.5 6.9 0.0 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CtnDOT_TraJ PF07863.11 KFH42741.1 - 2 9.1 6.3 4.6 8.0 2.0 2.3 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon MFS_1 PF07690.16 KFH42742.1 - 4.1e-39 134.5 36.0 4.8e-38 131.0 27.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42742.1 - 1e-07 31.2 3.5 1e-07 31.2 3.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFH42742.1 - 0.0057 15.1 2.3 0.01 14.3 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 2-Hacid_dh_C PF02826.19 KFH42743.1 - 1.5e-44 151.5 0.0 1.3e-29 102.8 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FR47 PF08445.10 KFH42744.1 - 2.7e-06 27.3 0.0 1.6e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KFH42744.1 - 0.0022 18.2 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4834 PF16118.5 KFH42745.1 - 0.23 12.4 0.0 0.39 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 KFH42745.1 - 1.8 8.1 13.4 3.4 7.2 13.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 KFH42745.1 - 3.5 7.0 11.7 0.26 10.7 6.9 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Dabb PF07876.12 KFH42746.1 - 1.2e-21 77.1 0.0 4e-21 75.5 0.0 1.7 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Sporozoite_P67 PF05642.11 KFH42747.1 - 0.047 11.8 10.6 0.06 11.4 10.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Podoplanin PF05808.11 KFH42747.1 - 0.16 12.1 5.3 0.28 11.3 5.3 1.3 1 0 0 1 1 1 0 Podoplanin Pyridox_oxase_2 PF12766.7 KFH42749.1 - 1.4e-19 70.6 0.0 2.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_4 PF13439.6 KFH42749.1 - 0.025 14.6 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 CFEM PF05730.11 KFH42750.1 - 3.7e-05 23.7 1.2 0.00012 22.1 1.2 1.9 1 0 0 1 1 1 1 CFEM domain Ras PF00071.22 KFH42751.1 - 2.3e-31 108.6 0.0 5e-24 84.7 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH42751.1 - 0.00027 21.2 0.0 0.089 13.0 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH42751.1 - 0.06 12.8 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Asp PF00026.23 KFH42753.1 - 4.5e-52 177.4 0.0 5.6e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH42753.1 - 3.2e-09 37.3 0.5 3.2e-08 34.0 0.5 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFH42753.1 - 9.9e-05 22.9 0.1 2.3 8.9 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KFH42753.1 - 0.019 15.5 0.0 4.4 7.9 0.0 3.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease SF3b10 PF07189.11 KFH42754.1 - 4e-39 132.6 0.0 4.6e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DEAD PF00270.29 KFH42755.1 - 6.3e-42 143.3 0.0 1.4e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH42755.1 - 2.4e-28 98.7 0.0 1.4e-27 96.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH42755.1 - 3.9e-05 23.7 0.0 9.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFH42755.1 - 0.021 14.1 0.7 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Zn_clus PF00172.18 KFH42756.1 - 0.0033 17.5 11.2 0.0053 16.8 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.14 KFH42757.1 - 2.3e-46 157.9 0.2 3.9e-46 157.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFH42757.1 - 6.4e-20 71.8 0.0 1.1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Amino_oxidase PF01593.24 KFH42759.1 - 8.3e-22 78.1 1.0 4.9e-21 75.6 0.1 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH42759.1 - 5.6e-16 58.5 0.2 1.8e-15 56.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH42759.1 - 5.2e-11 42.7 1.1 9.7e-10 38.5 1.1 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH42759.1 - 5.9e-08 32.3 0.2 4.4e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH42759.1 - 2.1e-06 27.1 4.1 2.1e-05 23.8 4.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFH42759.1 - 3e-06 26.2 0.1 0.0005 18.9 1.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KFH42759.1 - 0.00021 20.7 0.7 0.00038 19.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFH42759.1 - 0.00024 20.4 0.8 0.00038 19.8 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH42759.1 - 0.00027 21.0 1.3 0.02 14.9 0.6 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFH42759.1 - 0.00037 21.0 1.5 0.0026 18.3 1.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH42759.1 - 0.00059 19.3 3.5 0.0011 18.4 3.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFH42759.1 - 0.0031 16.6 1.3 0.0031 16.6 1.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KFH42759.1 - 0.005 16.1 0.4 0.0087 15.3 0.4 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 KFH42759.1 - 0.0071 16.0 0.5 0.016 14.8 0.4 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 KFH42759.1 - 0.055 14.0 0.0 0.41 11.2 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain GDI PF00996.18 KFH42759.1 - 0.056 11.9 0.1 5.8 5.3 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor GIDA PF01134.22 KFH42759.1 - 0.058 12.5 3.2 0.19 10.8 2.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KFH42759.1 - 0.074 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 KFH42759.1 - 0.11 11.9 0.9 0.27 10.7 0.7 1.7 2 0 0 2 2 2 0 short chain dehydrogenase 3HCDH_N PF02737.18 KFH42759.1 - 0.17 11.8 0.7 0.28 11.0 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KFH42759.1 - 0.18 10.6 1.1 7.2 5.3 1.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase SLS PF14611.6 KFH42760.1 - 1.8e-23 83.5 0.5 1.2e-22 80.9 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KFH42761.1 - 5.2e-54 182.7 0.1 7.5e-54 182.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFH42761.1 - 3.5e-41 140.0 0.0 7.1e-41 139.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFH42761.1 - 5.6e-15 55.5 1.1 1.1e-14 54.5 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH42761.1 - 0.00022 21.3 0.1 0.0052 16.9 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFH42761.1 - 0.051 13.5 0.3 0.17 11.8 0.3 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 bVLRF1 PF18826.1 KFH42762.1 - 1.8e-62 209.6 0.1 4.5e-62 208.3 0.1 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KFH42762.1 - 1.9e-06 28.0 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFH42762.1 - 0.012 16.1 0.2 0.033 14.6 0.2 1.8 1 0 0 1 1 1 0 Ankyrin repeat DUF4719 PF15843.5 KFH42762.1 - 0.032 14.3 0.1 0.032 14.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Ank_2 PF12796.7 KFH42762.1 - 0.097 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1674 PF07896.12 KFH42764.1 - 1.2e-16 60.8 13.5 1.1e-15 57.9 13.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Sugar_tr PF00083.24 KFH42765.1 - 6.3e-96 322.0 23.8 8e-96 321.6 23.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42765.1 - 7.4e-23 81.0 15.4 7.4e-23 81.0 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_34 PF05637.12 KFH42766.1 - 3e-08 33.7 1.1 4.6e-08 33.1 1.1 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KFH42766.1 - 6.1e-06 26.4 0.0 2e-05 24.7 0.0 1.7 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 KFH42766.1 - 0.00021 20.9 0.1 0.00034 20.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 NTP_transf_9 PF04248.12 KFH42767.1 - 3.5e-41 139.0 0.3 1.9e-29 101.4 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) MFS_1 PF07690.16 KFH42769.1 - 1.2e-14 54.1 3.2 1.4e-14 53.8 3.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH42769.1 - 8.3e-07 28.2 0.0 8.7e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFH42769.1 - 0.00047 18.7 0.0 0.0005 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KFH42769.1 - 0.016 14.1 0.5 0.019 13.9 0.5 1.1 1 0 0 1 1 1 0 MFS_1 like family DUF2178 PF09946.9 KFH42769.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF647 PF04884.14 KFH42770.1 - 7.3e-92 307.4 1.2 9.8e-92 306.9 1.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Lactamase_B PF00753.27 KFH42771.1 - 0.00023 21.2 0.3 0.00035 20.7 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 KFH42771.1 - 0.00058 19.4 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MCU PF04678.13 KFH42772.1 - 1.3e-24 87.2 0.1 3.2e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial calcium uniporter NmrA PF05368.13 KFH42775.1 - 5.8e-25 88.2 0.0 7.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH42775.1 - 6e-22 78.4 0.0 8.4e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFH42775.1 - 2.9e-05 24.3 0.1 9.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFH42775.1 - 0.00025 20.6 0.1 0.0018 17.8 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFH42775.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KFH42775.1 - 0.016 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Succ_CoA_lig PF13607.6 KFH42775.1 - 0.083 12.7 0.6 12 5.6 0.4 2.7 2 1 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Pyrophosphatase PF00719.19 KFH42778.1 - 2.4e-34 118.5 1.5 3.6e-30 104.9 0.4 3.2 1 1 1 2 2 2 2 Inorganic pyrophosphatase Lac_bphage_repr PF06543.12 KFH42778.1 - 0.13 12.3 2.1 0.66 10.0 0.2 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor PNK3P PF08645.11 KFH42779.1 - 4.2e-54 182.6 0.0 6.6e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KFH42779.1 - 7.5e-30 104.0 0.0 6e-16 58.9 0.0 2.6 2 1 1 3 3 3 2 AAA domain DUF3046 PF11248.8 KFH42779.1 - 0.0092 16.3 0.0 0.4 11.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3046) AAA_22 PF13401.6 KFH42779.1 - 0.0096 16.2 0.0 0.027 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFH42779.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KFH42779.1 - 0.02 15.4 0.3 3 8.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 KFH42779.1 - 0.022 14.2 0.2 2 7.8 0.0 2.2 1 1 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFH42779.1 - 0.026 14.9 0.0 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KFH42779.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KFH42779.1 - 0.088 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH42779.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KFH42779.1 - 0.11 11.8 0.0 0.87 8.8 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KFH42779.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH42779.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Macro_2 PF14519.6 KFH42781.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Macro-like domain tRNA-synt_1c PF00749.21 KFH42782.1 - 1e-99 333.4 0.0 1.3e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFH42782.1 - 1.2e-38 132.7 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KFH42782.1 - 0.0022 17.4 0.7 0.0045 16.4 0.5 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Glyco_hydro_10 PF00331.20 KFH42785.1 - 4.9e-99 331.5 0.0 5.5e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF834 PF05754.14 KFH42785.1 - 0.11 12.5 0.4 0.11 12.5 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF834) PHO4 PF01384.20 KFH42788.1 - 3.4e-115 384.7 10.1 3.9e-115 384.5 10.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family zf-TFIIB PF13453.6 KFH42789.1 - 0.053 12.9 0.8 5 6.5 0.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger CLN3 PF02487.17 KFH42790.1 - 6.4e-156 519.4 5.2 7.4e-156 519.2 5.2 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KFH42790.1 - 0.077 11.9 30.8 0.29 10.0 11.4 2.9 1 1 1 2 2 2 0 Major Facilitator Superfamily GST_N PF02798.20 KFH42791.1 - 9.3e-07 29.1 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFH42791.1 - 9.9e-07 29.1 0.0 2.2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFH42791.1 - 0.0023 18.1 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFH42791.1 - 0.0025 18.1 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH42791.1 - 0.0038 17.2 0.1 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH42791.1 - 0.0058 16.8 0.0 0.017 15.3 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Cyto_heme_lyase PF01265.17 KFH42792.1 - 1.5e-45 156.1 12.9 7.6e-43 147.2 12.9 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MFS_1 PF07690.16 KFH42793.1 - 2.8e-15 56.1 24.2 1.7e-10 40.4 3.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MttA_Hcf106 PF02416.16 KFH42793.1 - 0.29 10.5 1.9 0.64 9.4 1.9 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family DUF4191 PF13829.6 KFH42793.1 - 1.6 8.0 7.8 3 7.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) MDD_C PF18376.1 KFH42794.1 - 5.5e-62 208.8 0.0 7.5e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KFH42794.1 - 1.1e-08 35.1 2.7 2e-08 34.4 1.5 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Acetyltransf_8 PF13523.6 KFH42795.1 - 6.6e-39 132.9 0.0 1.1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3292 PF11696.8 KFH42796.1 - 1.5e-265 882.7 0.0 1.7e-265 882.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Rxt3 PF08642.10 KFH42797.1 - 6.5e-42 143.3 0.0 6.5e-42 143.3 0.0 3.8 4 0 0 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KFH42797.1 - 3.7e-05 23.7 0.0 0.0065 16.6 0.0 2.4 2 0 0 2 2 2 2 LCCL domain zf-C2H2_4 PF13894.6 KFH42798.1 - 5.5e-07 29.9 8.7 0.0011 19.6 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH42798.1 - 6.4e-07 29.5 10.7 8.7e-05 22.8 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH42798.1 - 0.003 17.9 2.2 0.072 13.6 0.5 3.0 2 0 0 2 2 2 1 Zinc-finger double domain Fungal_trans PF04082.18 KFH42798.1 - 0.0031 16.6 0.0 0.12 11.3 0.0 2.2 1 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 KFH42798.1 - 0.0097 16.2 0.3 0.56 10.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFH42798.1 - 0.27 11.6 3.8 0.9 9.9 3.8 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cytochrome_C7 PF14522.6 KFH42798.1 - 0.52 10.3 6.4 0.2 11.7 3.0 2.1 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-C2HC_2 PF13913.6 KFH42798.1 - 1.4 8.9 6.1 0.5 10.3 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Med18 PF09637.10 KFH42801.1 - 5.3e-24 85.4 0.0 6.6e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.24 KFH42802.1 - 1.7e-81 274.4 21.2 2.1e-81 274.1 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH42802.1 - 2.5e-18 66.2 60.3 6.7e-15 54.9 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 KFH42803.1 - 6.3e-08 32.9 0.4 1.1e-07 32.1 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFH42803.1 - 3e-06 26.9 0.4 0.072 12.6 0.1 2.4 2 1 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.12 KFH42803.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Amidohydro_1 PF01979.20 KFH42804.1 - 3.6e-28 98.9 0.0 9.5e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH42804.1 - 5.8e-15 55.7 1.2 4.8e-09 36.2 0.1 2.5 3 0 0 3 3 3 2 Amidohydrolase family Dynamin_N PF00350.23 KFH42805.1 - 1.1e-31 110.1 0.0 3.1e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH42805.1 - 2.1e-24 86.2 0.1 5.7e-24 84.8 0.1 1.8 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KFH42805.1 - 1.2e-07 31.8 0.1 5.8e-07 29.6 0.1 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFH42805.1 - 5.1e-05 23.3 0.1 0.0003 20.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFH42805.1 - 0.016 15.0 0.7 0.038 13.7 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 KFH42805.1 - 0.019 14.8 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KFH42805.1 - 0.03 13.9 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Elong_Iki1 PF10483.9 KFH42805.1 - 0.042 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_16 PF13191.6 KFH42805.1 - 0.059 13.7 2.2 4.4 7.7 0.0 3.7 2 1 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 KFH42805.1 - 0.081 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AviRa PF11599.8 KFH42805.1 - 0.11 12.0 0.0 0.31 10.4 0.0 1.8 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF3008 PF11450.8 KFH42805.1 - 0.12 12.6 0.2 0.32 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) AAA_23 PF13476.6 KFH42805.1 - 1.8 9.0 6.4 3.3 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain MutS_III PF05192.18 KFH42805.1 - 6.2 7.0 8.8 39 4.4 4.3 2.9 1 1 1 2 2 2 0 MutS domain III PhzC-PhzF PF02567.16 KFH42807.1 - 1.2e-37 130.0 0.0 1.8e-37 129.4 0.0 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein NARP1 PF12569.8 KFH42810.1 - 4e-197 656.2 29.2 3.2e-196 653.2 22.8 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KFH42810.1 - 8.1e-21 74.3 33.4 2e-05 25.0 0.1 7.9 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFH42810.1 - 2.5e-20 72.9 29.9 2.3e-05 25.0 5.3 9.9 7 1 4 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFH42810.1 - 6.7e-20 69.6 24.0 0.00017 21.4 0.3 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42810.1 - 1.3e-18 66.0 23.6 0.0014 19.3 0.1 9.9 7 3 3 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFH42810.1 - 1.5e-16 59.5 20.7 1.9e-05 24.2 0.5 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFH42810.1 - 4.3e-12 45.5 10.6 3.7e-06 26.5 0.2 6.7 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 KFH42810.1 - 1.3e-11 43.8 17.9 0.00078 19.5 0.2 8.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFH42810.1 - 7.1e-10 38.9 16.6 0.00048 20.2 0.8 6.6 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFH42810.1 - 2.8e-09 36.7 13.4 0.0018 18.5 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH42810.1 - 3.1e-08 33.8 27.1 0.0064 16.8 0.4 7.3 6 1 2 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH42810.1 - 5.3e-07 29.8 22.3 0.0062 16.7 1.4 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFH42810.1 - 4.3e-05 22.9 19.7 0.024 13.9 2.6 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH42810.1 - 9e-05 22.9 22.8 0.57 10.9 0.1 7.9 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH42810.1 - 0.00015 21.5 12.1 4.7 7.5 0.1 6.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFH42810.1 - 0.00015 21.5 14.9 3.6 7.6 0.0 7.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.12 KFH42810.1 - 0.00054 20.5 3.3 1.6 9.5 0.1 4.0 2 1 1 3 3 3 2 Sel1 repeat TPR_4 PF07721.14 KFH42810.1 - 0.00084 19.7 7.5 0.42 11.4 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KFH42810.1 - 0.018 15.5 1.6 0.018 15.5 1.6 4.3 3 2 0 4 4 4 0 Bacterial transcriptional activator domain Type_III_YscG PF09477.10 KFH42810.1 - 0.032 14.3 0.8 0.74 9.9 0.2 2.8 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Coilin_N PF15862.5 KFH42810.1 - 0.41 10.5 3.4 0.89 9.4 3.4 1.6 1 0 0 1 1 1 0 Coilin N-terminus MIT PF04212.18 KFH42810.1 - 0.54 10.4 15.3 3.2 7.9 0.3 5.8 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 KFH42810.1 - 0.58 10.3 2.7 7.3 6.8 0.1 3.3 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 KFH42810.1 - 6 7.0 13.7 13 6.0 0.2 5.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KFH42810.1 - 8.9 6.4 14.1 0.81 9.8 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat CTV_P13 PF06922.11 KFH42811.1 - 0.2 11.7 0.6 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein tRNA_lig_CPD PF08302.11 KFH42813.1 - 7.2e-89 297.6 0.2 9.8e-89 297.1 0.2 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KFH42813.1 - 8.1e-87 290.7 0.0 1.5e-86 289.8 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KFH42813.1 - 4.4e-55 186.3 0.0 1.1e-54 185.0 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KFH42813.1 - 0.0055 17.2 0.2 0.95 10.0 0.2 3.4 2 1 0 2 2 2 1 AAA domain MAS20 PF02064.15 KFH42813.1 - 1.4 9.0 6.6 8.3 6.5 3.7 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor Ribosomal_S11 PF00411.19 KFH42814.1 - 3.7e-08 33.7 0.0 1.3e-07 32.0 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein S11 TetR_C_35 PF18556.1 KFH42815.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Vac_ImportDeg PF09783.9 KFH42816.1 - 3.3e-69 231.8 1.4 4.1e-69 231.5 1.4 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ribonuc_P_40 PF08584.11 KFH42817.1 - 3.5e-54 184.0 0.0 8e-54 182.8 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit Ku_C PF03730.14 KFH42818.1 - 0.38 11.5 1.7 1 10.1 1.7 1.8 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Cyt-b5 PF00173.28 KFH42819.1 - 5.5e-13 48.9 0.0 7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 KFH42820.1 - 5e-119 398.0 39.8 5.6e-119 397.8 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH42820.1 - 7.8e-29 100.7 45.3 1e-28 100.3 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease Adaptin_N PF01602.20 KFH42821.1 - 1.7e-91 307.4 8.8 3.3e-91 306.4 8.8 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFH42821.1 - 6.7e-60 201.0 0.8 1.4e-59 200.0 0.8 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFH42821.1 - 1.4e-56 189.9 0.0 4.3e-56 188.4 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFH42821.1 - 1.3e-11 44.9 3.7 2.3e-08 34.2 0.0 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFH42821.1 - 1.2e-07 32.0 5.5 8.4e-05 22.9 0.0 4.7 3 1 1 4 4 4 1 HEAT repeats Coatomer_g_Cpla PF16381.5 KFH42821.1 - 0.00014 21.9 0.0 0.00064 19.8 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KFH42821.1 - 0.0018 18.4 0.2 3.2 8.3 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.6 KFH42821.1 - 0.033 14.6 0.2 0.13 12.7 0.2 2.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KFH42821.1 - 0.042 14.4 0.8 3.7 8.1 0.0 4.4 5 1 1 6 6 6 0 HEAT-like repeat MMS22L_C PF14911.6 KFH42821.1 - 0.54 9.3 9.4 0.36 9.9 0.4 3.3 2 1 1 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal Oxysterol_BP PF01237.18 KFH42822.1 - 9.5e-66 222.1 0.5 1.6e-63 214.8 0.5 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein AAA PF00004.29 KFH42823.1 - 1e-39 136.0 0.0 1.9e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFH42823.1 - 4.7e-18 64.9 0.1 9.6e-18 63.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFH42823.1 - 4.1e-08 32.9 0.0 9.8e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFH42823.1 - 0.00014 22.3 1.7 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFH42823.1 - 0.00015 21.7 0.1 0.00071 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFH42823.1 - 0.00039 20.2 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH42823.1 - 0.0015 18.8 1.6 0.082 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KFH42823.1 - 0.0015 18.7 0.0 0.011 15.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KFH42823.1 - 0.0063 16.0 0.2 0.08 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFH42823.1 - 0.0078 15.6 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFH42823.1 - 0.011 14.9 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KFH42823.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFH42823.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFH42823.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFH42823.1 - 0.16 11.8 1.4 0.6 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain BCS1_N PF08740.11 KFH42824.1 - 7.7e-40 136.9 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KFH42824.1 - 1.8e-17 64.0 0.0 2.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFH42824.1 - 0.00013 21.6 0.0 0.014 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KFH42824.1 - 0.00035 20.1 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 KFH42824.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFH42824.1 - 0.0019 18.2 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFH42824.1 - 0.0033 17.8 0.0 0.01 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.13 KFH42824.1 - 0.0049 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KFH42824.1 - 0.0053 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH42824.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH42824.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH42824.1 - 0.014 15.9 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KFH42824.1 - 0.017 15.3 0.0 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFH42824.1 - 0.025 14.6 0.0 0.076 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 KFH42824.1 - 0.037 12.8 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase AAA_17 PF13207.6 KFH42824.1 - 0.067 13.6 0.1 0.48 10.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain GTSE1_N PF15259.6 KFH42824.1 - 0.079 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 RsgA_GTPase PF03193.16 KFH42824.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase FMN_bind PF04205.14 KFH42824.1 - 0.096 13.3 0.0 0.51 10.9 0.0 2.0 2 0 0 2 2 2 0 FMN-binding domain RNA_helicase PF00910.22 KFH42824.1 - 0.097 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KFH42824.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KFH42824.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 KFH42824.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFH42824.1 - 0.2 11.6 0.1 3 7.7 0.0 2.7 3 0 0 3 3 3 0 NACHT domain p450 PF00067.22 KFH42825.1 - 2.1e-75 254.3 0.0 2.5e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.6 KFH42826.1 - 2e-24 87.0 1.7 3.3e-24 86.2 1.7 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH42826.1 - 5e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Aldolase_II PF00596.21 KFH42826.1 - 0.0053 16.7 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain Enolase_C PF00113.22 KFH42829.1 - 3e-153 509.3 0.1 3.8e-153 508.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFH42829.1 - 3.1e-58 195.6 0.1 4.8e-58 195.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFH42829.1 - 2.4e-06 27.3 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFH42829.1 - 0.015 14.5 0.5 0.32 10.1 0.2 2.6 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Peptidase_C97 PF05903.14 KFH42830.1 - 3e-33 114.8 0.0 3.9e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFH42830.1 - 0.00056 20.2 0.0 0.00092 19.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Tim44 PF04280.15 KFH42831.1 - 1.1e-36 126.2 0.1 1.1e-35 122.9 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain Glyco_hydro_31 PF01055.26 KFH42832.1 - 2.5e-150 501.5 6.4 3.3e-150 501.1 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFH42832.1 - 1.4e-38 131.7 0.0 2.6e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFH42832.1 - 1.3e-13 51.1 0.3 1.3e-13 51.1 0.3 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Vps35 PF03635.17 KFH42834.1 - 6.2e-302 1003.6 0.0 7.2e-302 1003.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Reticulon PF02453.17 KFH42835.1 - 0.0042 17.1 1.1 0.0057 16.6 1.1 1.2 1 0 0 1 1 1 1 Reticulon UPF0020 PF01170.18 KFH42836.1 - 1e-08 35.2 0.0 4.2e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 KFH42836.1 - 0.21 11.3 0.0 0.79 9.4 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein Ank_5 PF13857.6 KFH42837.1 - 3.8e-09 36.6 0.1 1.8e-07 31.3 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH42837.1 - 1e-05 26.0 0.1 1.7e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH42837.1 - 1.2e-05 25.7 0.0 0.00024 21.6 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH42837.1 - 8.5e-05 22.7 1.1 0.0015 18.9 0.3 2.7 3 0 0 3 3 3 1 Ankyrin repeat GCV_T PF01571.21 KFH42837.1 - 0.0042 16.5 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DALR_2 PF09190.11 KFH42837.1 - 0.024 15.1 0.0 0.11 13.0 0.0 2.0 2 1 0 2 2 2 0 DALR domain Ank PF00023.30 KFH42837.1 - 0.093 13.2 0.3 0.43 11.1 0.3 2.1 2 0 0 2 2 2 0 Ankyrin repeat DAGK_cat PF00781.24 KFH42838.1 - 3.1e-27 94.7 0.0 4.9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SET PF00856.28 KFH42839.1 - 1.4e-19 71.1 0.0 6.5e-19 68.9 0.0 2.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFH42839.1 - 6.2e-07 30.0 5.2 1.5e-06 28.8 1.3 2.2 2 0 0 2 2 2 1 Pre-SET motif TFR_dimer PF04253.15 KFH42840.1 - 4.9e-30 104.1 0.2 9.6e-30 103.2 0.2 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFH42840.1 - 6.8e-21 74.9 0.0 1.4e-19 70.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFH42840.1 - 5.2e-13 48.8 0.1 1.2e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 KFH42840.1 - 0.032 13.7 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Mago_nashi PF02792.14 KFH42841.1 - 3.7e-68 228.1 0.2 4.2e-68 227.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF2263 PF10021.9 KFH42842.1 - 6.8e-22 78.4 0.0 1.1e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Ribosomal_L10 PF00466.20 KFH42843.1 - 0.00052 20.1 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L10 Cid2 PF09774.9 KFH42844.1 - 1e-54 185.3 0.0 1.2e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Dymeclin PF09742.9 KFH42844.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Ish1 PF10281.9 KFH42845.1 - 1.1e-80 265.6 24.0 1.6e-13 50.7 0.1 8.4 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KFH42845.1 - 2.4e-09 36.7 0.0 5.4 6.9 0.0 7.9 9 0 0 9 9 9 3 SAP domain Slx4 PF09494.10 KFH42845.1 - 3.9e-07 29.9 0.5 10 6.1 0.0 6.1 7 0 0 7 7 7 1 Slx4 endonuclease HeH PF12949.7 KFH42845.1 - 0.00041 20.0 0.1 1.5 8.6 0.0 5.1 6 0 0 6 6 6 1 HeH/LEM domain SAM_2 PF07647.17 KFH42845.1 - 0.07 13.3 0.3 2.1 8.5 0.0 3.3 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) LEA_4 PF02987.16 KFH42845.1 - 2.9 8.0 27.3 2.9 8.0 0.7 5.1 5 0 0 5 5 5 0 Late embryogenesis abundant protein F_bP_aldolase PF01116.20 KFH42846.1 - 4e-91 305.4 0.0 4.5e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II VPS9 PF02204.18 KFH42847.1 - 5.3e-20 71.6 0.2 1.4e-19 70.2 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KFH42847.1 - 7.4e-16 58.0 0.9 1e-13 51.2 0.0 4.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH42847.1 - 2.3e-13 50.5 0.5 0.00018 22.0 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH42847.1 - 9.9e-06 26.0 0.3 0.06 14.0 0.0 5.0 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH42847.1 - 1.8e-05 24.8 0.3 0.15 12.7 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KFH42847.1 - 0.028 14.9 0.7 11 6.7 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat PX PF00787.24 KFH42847.1 - 0.048 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 PX domain DUF5304 PF17230.2 KFH42847.1 - 0.059 13.6 2.7 0.34 11.1 0.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5304) BOP1NT PF08145.12 KFH42848.1 - 1.2e-105 353.1 5.7 1.8e-105 352.5 5.7 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFH42848.1 - 6.3e-22 77.5 6.2 6.3e-08 33.2 0.1 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH42848.1 - 0.00014 22.1 0.0 1.2 9.5 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 KFH42848.1 - 0.13 11.6 2.2 0.25 10.7 1.8 1.5 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CSN8_PSD8_EIF3K PF10075.9 KFH42849.1 - 0.06 13.3 0.1 0.1 12.6 0.1 1.5 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family YchF-GTPase_C PF06071.13 KFH42850.1 - 7.1e-35 119.1 0.1 2.5e-34 117.3 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFH42850.1 - 3.6e-15 56.0 0.0 1.2e-14 54.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KFH42850.1 - 2.7e-05 24.1 0.0 6.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 KFH42850.1 - 0.003 18.1 0.6 3.7 8.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain FeoB_N PF02421.18 KFH42850.1 - 0.03 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 KFH42850.1 - 0.06 13.6 0.1 5.2 7.3 0.0 3.4 3 2 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AKAP95 PF04988.12 KFH42850.1 - 0.069 13.4 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) BetaGal_dom3 PF13363.6 KFH42850.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 ABC_tran PF00005.27 KFH42850.1 - 0.099 13.2 0.9 2.1 8.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter DHHC PF01529.20 KFH42851.1 - 5.9e-37 126.8 8.1 5.9e-37 126.8 8.1 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase CFEM PF05730.11 KFH42852.1 - 1.2e-08 34.9 4.9 1.8e-08 34.3 4.9 1.2 1 0 0 1 1 1 1 CFEM domain OB_NTP_bind PF07717.16 KFH42853.1 - 1.3e-23 83.1 0.0 2.7e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFH42853.1 - 1e-22 80.5 0.0 1e-22 80.5 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH42853.1 - 1.2e-13 51.3 0.0 3.3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KFH42853.1 - 2.6e-10 40.5 0.4 5.2e-10 39.5 0.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KFH42853.1 - 2.9e-06 27.1 0.1 7.1e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFH42853.1 - 1.7e-05 25.1 0.0 5.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFH42853.1 - 0.00017 20.8 0.2 0.00048 19.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFH42853.1 - 0.00032 20.5 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFH42853.1 - 0.0077 16.6 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain RSRP PF17069.5 KFH42853.1 - 0.022 14.4 17.0 0.044 13.3 17.0 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 AAA_14 PF13173.6 KFH42853.1 - 0.029 14.4 0.2 0.49 10.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH42853.1 - 0.095 13.2 0.0 0.46 11.0 0.0 2.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFH42853.1 - 0.15 12.4 0.9 0.51 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Microtub_bd PF16796.5 KFH42853.1 - 0.16 11.9 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 KFH42853.1 - 0.16 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein TP_methylase PF00590.20 KFH42855.1 - 2.1e-44 152.0 0.2 3.8e-44 151.2 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KFH42855.1 - 4.2e-13 49.6 0.0 8.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KFH42855.1 - 8.1e-11 41.2 0.1 1.6e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KFH42855.1 - 1.1e-10 40.9 1.2 1.5e-09 37.3 0.2 2.7 2 1 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal DUF498 PF04430.14 KFH42855.1 - 0.041 14.0 0.0 0.25 11.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) NAT PF04768.13 KFH42857.1 - 7.4e-45 152.7 0.0 1.3e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KFH42857.1 - 8.3e-31 107.4 0.0 1.7e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Methyltransf_3 PF01596.17 KFH42857.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Zn_clus PF00172.18 KFH42859.1 - 3.5e-07 30.3 10.8 3.5e-07 30.3 10.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KFH42860.1 - 0.072 13.2 6.6 0.13 12.4 6.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KFH42861.1 - 2.3e-48 164.1 6.1 6e-48 162.8 6.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFH42861.1 - 5.5e-26 92.2 0.1 9e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFH42861.1 - 8.5e-06 26.1 0.2 4.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFH42861.1 - 0.029 14.1 0.6 0.09 12.5 0.2 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFH42861.1 - 0.084 13.3 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CLP1_P PF16575.5 KFH42863.1 - 1.7e-37 129.0 0.0 2.8e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KFH42863.1 - 3.7e-26 91.2 0.0 6.7e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KFH42863.1 - 2.6e-22 79.4 0.0 2e-21 76.6 0.0 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 KFH42863.1 - 1.6e-05 25.4 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KFH42863.1 - 2e-05 24.5 0.1 5.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFH42863.1 - 0.00023 21.2 0.0 0.00094 19.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KFH42863.1 - 0.00023 21.2 0.0 0.00052 20.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KFH42863.1 - 0.0041 16.8 0.0 0.32 10.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain KTI12 PF08433.10 KFH42863.1 - 0.0057 16.1 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 KFH42863.1 - 0.007 16.1 0.0 0.021 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFH42863.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFH42863.1 - 0.0075 16.0 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFH42863.1 - 0.011 16.3 0.0 0.067 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFH42863.1 - 0.04 14.2 0.0 0.067 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KFH42863.1 - 0.055 12.6 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Sigma54_activat PF00158.26 KFH42863.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 KFH42863.1 - 0.081 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DUF1611 PF07755.11 KFH42863.1 - 0.082 12.2 0.4 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Cytidylate_kin PF02224.18 KFH42863.1 - 0.13 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase Asparaginase_C PF17763.1 KFH42863.1 - 0.15 12.3 0.3 0.49 10.6 0.3 1.9 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain AAA PF00004.29 KFH42863.1 - 0.16 12.4 0.1 0.95 9.9 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFH42863.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KFH42863.1 - 0.21 11.6 0.0 0.74 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH42863.1 - 0.22 12.0 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Glyco_hydro_76 PF03663.14 KFH42864.1 - 0.17 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Thioredoxin PF00085.20 KFH42865.1 - 3.7e-26 91.1 0.1 5.9e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFH42865.1 - 0.00013 22.4 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFH42865.1 - 0.00016 21.6 0.0 0.00038 20.4 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFH42865.1 - 0.00019 21.7 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFH42865.1 - 0.00054 19.4 0.8 0.00079 18.9 0.1 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFH42865.1 - 0.0015 18.3 0.1 0.0022 17.7 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFH42865.1 - 0.039 13.7 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KFH42865.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like LIAS_N PF16881.5 KFH42866.1 - 4e-18 65.8 0.0 7.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFH42866.1 - 1.4e-10 41.8 0.0 2.7e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer2_3 PF13085.6 KFH42867.1 - 2.7e-33 114.3 0.0 4.8e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFH42867.1 - 1.1e-08 35.5 6.2 1.1e-08 35.5 6.2 2.5 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFH42867.1 - 1.1e-07 31.9 3.0 1.1e-07 31.9 3.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFH42867.1 - 3.7e-07 30.5 9.3 3.7e-07 30.5 9.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KFH42867.1 - 0.0028 17.6 3.5 0.0038 17.2 0.5 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KFH42867.1 - 0.0056 17.2 5.7 0.0056 17.2 5.7 2.5 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFH42867.1 - 0.015 15.5 0.4 0.47 10.7 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFH42867.1 - 0.28 11.4 12.5 2.6 8.3 10.8 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFH42867.1 - 0.45 11.5 9.7 1.8 9.5 1.4 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain DNA_pol3_tau_4 PF12168.8 KFH42867.1 - 0.54 10.8 3.1 0.56 10.8 0.7 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding PAPS_reduct PF01507.19 KFH42868.1 - 2.5e-38 131.8 0.0 3.4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF5363 PF17320.2 KFH42868.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5363) DUF1690 PF07956.11 KFH42869.1 - 1.1e-43 148.9 6.3 1.3e-43 148.7 6.3 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) BshC PF10079.9 KFH42869.1 - 0.0071 15.1 2.0 0.0075 15.1 2.0 1.2 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Glyco_hydro_108 PF05838.12 KFH42869.1 - 0.14 12.6 0.4 0.44 11.1 0.1 2.0 1 1 0 2 2 2 0 Glycosyl hydrolase 108 YtxH PF12732.7 KFH42869.1 - 0.81 10.3 6.1 3.7 8.1 3.0 2.7 1 1 2 3 3 3 0 YtxH-like protein FUSC PF04632.12 KFH42869.1 - 1.4 7.3 4.0 1.7 7.1 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ABC_tran PF00005.27 KFH42870.1 - 3e-49 167.0 0.0 3.6e-27 95.5 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFH42870.1 - 7.8e-16 58.7 5.9 6.3e-05 22.9 1.6 5.2 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFH42870.1 - 1.2e-14 54.2 0.0 5e-06 26.1 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH42870.1 - 2.8e-09 37.8 1.0 0.0001 22.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KFH42870.1 - 2e-07 31.1 0.0 0.0049 17.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH42870.1 - 5.6e-07 29.6 0.1 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFH42870.1 - 6e-07 29.1 0.5 0.0093 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 KFH42870.1 - 2.3e-06 27.4 0.5 5.6e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 KFH42870.1 - 0.00012 22.3 0.3 1.2 9.4 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFH42870.1 - 0.00018 21.3 0.1 0.17 11.5 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KFH42870.1 - 0.00022 21.8 0.0 0.12 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH42870.1 - 0.00025 21.3 0.0 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFH42870.1 - 0.0011 19.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KFH42870.1 - 0.0011 18.9 0.1 0.54 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 KFH42870.1 - 0.0017 18.5 0.8 0.69 10.0 0.1 3.3 3 0 0 3 3 2 1 Helicase HerA, central domain MeaB PF03308.16 KFH42870.1 - 0.0017 17.4 0.2 0.49 9.3 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KFH42870.1 - 0.0032 17.6 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFH42870.1 - 0.0067 16.9 0.0 5.7 7.4 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KFH42870.1 - 0.0079 16.4 0.0 4.4 7.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KFH42870.1 - 0.0089 14.7 0.0 0.93 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFH42870.1 - 0.012 15.3 0.8 0.84 9.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFH42870.1 - 0.014 15.1 3.7 2.6 7.7 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFH42870.1 - 0.016 15.6 0.2 4.7 7.6 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.9 KFH42870.1 - 0.017 14.9 0.0 0.89 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SR-25 PF10500.9 KFH42870.1 - 0.021 14.4 0.7 0.036 13.7 0.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF815 PF05673.13 KFH42870.1 - 0.032 13.4 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KFH42870.1 - 0.034 13.7 1.0 7.4 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KFH42870.1 - 0.036 13.3 0.1 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KFH42870.1 - 0.048 13.7 0.0 0.9 9.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family ALF PF03752.13 KFH42870.1 - 0.062 13.3 2.4 8.7 6.4 0.3 2.7 2 0 0 2 2 2 0 Short repeats of unknown function Roc PF08477.13 KFH42870.1 - 0.066 13.4 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KFH42870.1 - 0.082 12.9 0.3 20 5.2 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 KFH42870.1 - 0.13 9.8 1.0 4.3 4.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Septin PF00735.18 KFH42870.1 - 0.14 11.4 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 KFH42870.1 - 0.16 12.0 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFH42870.1 - 0.18 11.7 0.6 25 4.7 0.5 2.8 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KFH42870.1 - 0.45 10.3 1.9 26 4.5 0.0 3.3 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ketoacyl-synt PF00109.26 KFH42871.1 - 2.5e-70 236.9 0.7 2.5e-70 236.9 0.7 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFH42871.1 - 2e-56 191.4 0.0 3.4e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH42871.1 - 5.6e-51 173.9 0.8 9.4e-51 173.2 0.8 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH42871.1 - 5.9e-48 163.2 0.1 1.2e-47 162.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFH42871.1 - 1.3e-36 125.2 0.0 7.3e-36 122.8 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFH42871.1 - 3.1e-15 56.6 0.0 4.8e-14 52.8 0.0 2.5 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KFH42871.1 - 4.6e-15 55.7 0.0 1.5e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH42871.1 - 2e-13 51.5 0.0 7.5e-13 49.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFH42871.1 - 1.2e-06 28.1 0.1 2.9e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 KFH42871.1 - 4.3e-05 23.3 0.3 9.9e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KFH42871.1 - 0.00069 19.9 0.3 0.0025 18.1 0.3 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFH42871.1 - 0.0018 17.7 0.5 0.0018 17.7 0.5 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF2807 PF10988.8 KFH42871.1 - 0.15 11.9 0.1 7.4 6.3 0.1 2.7 3 0 0 3 3 3 0 Putative auto-transporter adhesin, head GIN domain DUF3084 PF11283.8 KFH42871.1 - 0.15 12.1 0.1 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) ACP_syn_III PF08545.10 KFH42871.1 - 0.16 11.8 1.7 0.51 10.2 1.7 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III B12D PF06522.11 KFH42872.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Sulf_transp PF04143.14 KFH42872.1 - 0.13 11.8 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Sulphur transport RRM_1 PF00076.22 KFH42873.1 - 9.8e-16 57.3 0.0 1.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ferric_reduct PF01794.19 KFH42874.1 - 2.8e-24 85.6 7.2 7.1e-24 84.3 7.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH42874.1 - 2.6e-18 66.6 0.0 2.2e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH42874.1 - 1.1e-08 35.1 0.0 1.9e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 FAD-binding domain IPK PF03770.16 KFH42875.1 - 5.4e-47 160.2 0.0 6.9e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1847 PF08901.11 KFH42875.1 - 0.044 13.4 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) Ribonuclease_3 PF00636.26 KFH42876.1 - 1.7e-47 160.4 0.2 5.7e-23 81.5 0.0 3.5 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFH42876.1 - 9.7e-30 103.4 0.0 5.8e-12 45.9 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KFH42876.1 - 3.5e-18 65.5 0.0 5.1e-17 61.8 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KFH42876.1 - 5.7e-17 62.1 0.1 4.5e-16 59.2 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH42876.1 - 1.4e-10 41.2 0.1 3.1e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFH42876.1 - 4.7e-09 36.5 0.4 1.1e-08 35.2 0.4 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.22 KFH42876.1 - 0.0015 18.3 0.0 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 PAZ domain ERCC3_RAD25_C PF16203.5 KFH42876.1 - 0.051 12.8 0.1 0.14 11.3 0.1 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Synaptobrevin PF00957.21 KFH42877.1 - 3e-27 94.2 0.4 3.7e-27 93.9 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KFH42877.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor Peptidase_C12 PF01088.21 KFH42878.1 - 1.2e-53 182.0 0.0 2e-53 181.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans PF04082.18 KFH42879.1 - 6.3e-17 61.5 0.1 1.7e-16 60.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.28 KFH42881.1 - 7.1e-11 42.3 0.0 9.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF2635 PF10948.8 KFH42881.1 - 0.09 12.5 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Iso_dh PF00180.20 KFH42882.1 - 2.8e-65 220.8 0.0 4e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-MYND PF01753.18 KFH42883.1 - 0.52 10.5 5.3 1.1 9.4 5.3 1.6 1 0 0 1 1 1 0 MYND finger NmrA PF05368.13 KFH42884.1 - 9e-31 107.2 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH42884.1 - 3e-20 72.9 0.0 4.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH42884.1 - 6.9e-07 29.0 0.0 2.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH42884.1 - 0.005 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFH42884.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Rsm22 PF09243.10 KFH42885.1 - 7.5e-30 104.1 0.1 6.9e-29 101.0 0.1 2.4 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 DRE2_N PF16803.5 KFH42885.1 - 0.031 14.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus Methyltransf_12 PF08242.12 KFH42885.1 - 0.043 14.6 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFH42885.1 - 0.21 12.3 0.2 0.91 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.22 KFH42886.1 - 8e-94 315.2 1.0 1.1e-93 314.8 1.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFH42886.1 - 0.0014 18.1 0.0 0.092 12.1 0.0 2.3 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFH42886.1 - 0.081 13.0 0.7 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 PglZ domain zf-MYND PF01753.18 KFH42887.1 - 1.6e-05 24.9 1.9 2.2e-05 24.4 1.9 1.2 1 0 0 1 1 1 1 MYND finger HAD PF12710.7 KFH42888.1 - 2.8e-20 73.5 0.0 4e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH42888.1 - 2.4e-13 50.9 0.8 4.7e-13 49.9 0.8 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFH42888.1 - 1.4e-08 34.8 2.0 4.1e-08 33.3 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFH42888.1 - 0.0066 16.6 0.7 2.9 7.9 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KFH42888.1 - 0.0077 15.7 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 KFH42888.1 - 0.16 11.3 0.1 9.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Methyltrn_RNA_3 PF02598.17 KFH42889.1 - 1.8e-106 355.8 0.0 2.1e-106 355.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Lyase_1 PF00206.20 KFH42890.1 - 6.3e-20 71.8 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFH42890.1 - 2.7e-13 50.3 0.4 9e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus TYW3 PF02676.14 KFH42891.1 - 1.4e-77 259.8 0.0 1.8e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Phage_integrase PF00589.22 KFH42891.1 - 0.032 14.0 0.2 0.049 13.4 0.2 1.3 1 0 0 1 1 1 0 Phage integrase family EMG1 PF03587.14 KFH42895.1 - 8.2e-78 260.5 0.0 1e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SRP14 PF02290.15 KFH42896.1 - 2.5e-28 98.3 0.1 4.1e-28 97.6 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein SF3a60_bindingd PF12108.8 KFH42896.1 - 0.019 14.8 0.5 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Cys_Met_Meta_PP PF01053.20 KFH42897.1 - 2.4e-35 121.8 0.0 3.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme COQ9 PF08511.11 KFH42898.1 - 1.4e-33 114.5 0.0 2.5e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 COQ9 DnaJ PF00226.31 KFH42899.1 - 2.2e-24 85.4 1.1 5.2e-24 84.2 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KFH42899.1 - 1.6e-09 37.8 1.7 1.6e-09 37.8 1.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH42899.1 - 1.2e-08 35.0 8.2 4.4e-08 33.3 2.2 2.8 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFH42899.1 - 2.2e-07 31.1 6.5 0.0018 18.5 1.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFH42899.1 - 1e-06 29.1 2.8 0.014 16.2 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH42899.1 - 2.1e-06 27.8 4.9 0.017 15.6 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFH42899.1 - 0.0013 19.4 1.6 0.85 10.3 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFH42899.1 - 0.0023 17.9 5.5 0.57 10.3 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.6 KFH42899.1 - 0.019 14.9 0.1 0.061 13.3 0.1 1.9 1 1 0 1 1 1 0 A repeated domain in UCH-protein PHD_4 PF16866.5 KFH42899.1 - 1.5 8.9 4.3 3.2 7.9 1.0 2.5 2 0 0 2 2 2 0 PHD-finger DUF2256 PF10013.9 KFH42899.1 - 1.8 8.7 6.2 14 5.9 0.0 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) SGT1 PF07093.11 KFH42900.1 - 3.1e-94 316.5 17.0 2.9e-84 283.6 0.0 2.1 2 0 0 2 2 2 2 SGT1 protein NUDIX PF00293.28 KFH42900.1 - 0.016 15.3 0.2 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 NUDIX domain Lin-8 PF03353.15 KFH42900.1 - 2 7.9 7.2 3.1 7.3 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_C54 PF03416.19 KFH42901.1 - 7.4e-61 206.0 0.0 1.1e-60 205.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 AAA PF00004.29 KFH42902.1 - 3.4e-37 127.8 0.0 5.8e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH42902.1 - 1.3e-09 37.6 0.0 3.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KFH42902.1 - 1.8e-08 34.3 0.1 2.8e-07 30.4 0.0 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFH42902.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH42902.1 - 0.00015 22.0 1.3 0.0012 19.1 0.0 2.7 3 1 1 4 4 2 1 AAA domain AAA_16 PF13191.6 KFH42902.1 - 0.00077 19.9 0.4 0.0043 17.4 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFH42902.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFH42902.1 - 0.0025 17.8 0.0 0.0079 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH42902.1 - 0.0033 17.6 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFH42902.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFH42902.1 - 0.0054 16.1 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFH42902.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KFH42902.1 - 0.044 13.9 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH42902.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFH42902.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH42902.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KFH42902.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH42902.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFH42902.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain EIID-AGA PF03613.14 KFH42902.1 - 0.31 10.2 0.0 0.48 9.6 0.0 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component APG9 PF04109.16 KFH42903.1 - 2.7e-193 643.4 13.1 3.1e-193 643.1 13.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 FA_desaturase PF00487.24 KFH42904.1 - 1.1e-26 94.2 23.6 1.7e-26 93.6 23.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFH42904.1 - 9.4e-11 41.7 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain R3H PF01424.22 KFH42905.1 - 7.8e-15 54.6 0.0 1.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KFH42905.1 - 4e-09 36.2 2.6 9.2e-09 35.1 2.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFH42905.1 - 0.0021 18.1 2.3 0.0021 18.1 2.3 2.6 3 0 0 3 3 3 1 G-patch domain MIF4G PF02854.19 KFH42906.1 - 2.4e-25 89.4 0.0 6.6e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KFH42906.1 - 2.2e-08 34.1 0.0 8.3e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 MA3 domain Histone PF00125.24 KFH42907.1 - 6.8e-17 62.0 0.0 9.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFH42907.1 - 9.1e-07 28.5 0.1 1.8e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFH42907.1 - 6.8e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 KFH42908.1 - 1.6e-56 188.2 8.9 7.3e-22 77.1 0.1 3.7 2 2 1 3 3 3 3 Mitochondrial carrier protein Crystall PF00030.19 KFH42909.1 - 0.16 12.2 0.1 0.49 10.6 0.1 1.8 2 0 0 2 2 2 0 Beta/Gamma crystallin Gly-zipper_OmpA PF13436.6 KFH42909.1 - 0.36 10.7 4.1 0.7 9.7 4.1 1.4 1 0 0 1 1 1 0 Glycine-zipper domain Dor1 PF04124.12 KFH42910.1 - 0.024 13.3 0.5 0.04 12.6 0.5 1.3 1 0 0 1 1 1 0 Dor1-like family CLZ PF16526.5 KFH42910.1 - 0.48 10.8 3.3 1.5 9.3 0.1 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Filament PF00038.21 KFH42910.1 - 0.54 9.8 4.7 2.9 7.4 3.8 2.5 1 1 1 2 2 2 0 Intermediate filament protein Ribosomal_S17 PF00366.20 KFH42911.1 - 7.9e-18 64.3 0.7 2.5e-17 62.7 0.7 1.8 1 1 0 1 1 1 1 Ribosomal protein S17 PEPCK_N PF17297.2 KFH42911.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain RelB PF04221.12 KFH42911.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Podoplanin PF05808.11 KFH42913.1 - 0.0074 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Podoplanin RRM_1 PF00076.22 KFH42915.1 - 2.8e-35 120.0 0.0 2.9e-16 59.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 KFH42915.1 - 0.00059 19.5 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Limkain-b1 PF11608.8 KFH42915.1 - 0.0036 17.3 0.0 1.1 9.3 0.0 3.4 2 2 0 2 2 2 1 Limkain b1 RRM_occluded PF16842.5 KFH42915.1 - 0.085 12.7 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Keratin_2_head PF16208.5 KFH42915.1 - 7.1 6.7 48.8 3.9 7.6 30.2 2.6 2 0 0 2 2 2 0 Keratin type II head SPX PF03105.19 KFH42916.1 - 1.4e-58 199.7 7.0 6.8e-58 197.4 7.0 1.9 1 1 0 1 1 1 1 SPX domain zf-C3HC4_2 PF13923.6 KFH42916.1 - 8e-08 32.0 10.1 1.6e-07 31.0 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH42916.1 - 9.1e-08 31.9 10.4 1.9e-07 30.8 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH42916.1 - 2.3e-07 30.6 9.4 4.3e-07 29.7 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFH42916.1 - 3.2e-07 30.4 9.3 3.2e-07 30.4 9.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFH42916.1 - 1.2e-05 25.5 11.0 2.6e-05 24.4 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFH42916.1 - 3.7e-05 23.6 9.7 8.8e-05 22.4 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH42916.1 - 0.00045 20.2 10.4 0.0011 18.9 10.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFH42916.1 - 0.018 14.8 5.5 0.018 14.8 5.5 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFH42916.1 - 0.024 14.5 10.3 0.085 12.7 10.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KFH42916.1 - 0.035 14.0 2.7 0.087 12.7 2.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFH42916.1 - 0.037 14.1 1.6 0.073 13.1 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFH42916.1 - 0.04 14.2 9.6 0.11 12.9 9.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KFH42916.1 - 0.15 12.2 1.2 0.32 11.1 1.2 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KFH42916.1 - 0.89 9.7 8.9 0.92 9.7 7.0 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 FYVE_2 PF02318.16 KFH42916.1 - 2.8 8.2 7.2 45 4.3 0.0 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger RRM_1 PF00076.22 KFH42917.1 - 6.9e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPA_C PF08784.11 KFH42917.1 - 0.11 13.1 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 Replication protein A C terminal COG6 PF06419.11 KFH42919.1 - 1.8e-200 667.3 2.0 2.1e-200 667.1 2.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KFH42919.1 - 0.0067 16.5 0.3 0.0067 16.5 0.3 3.1 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.16 KFH42919.1 - 0.019 14.1 0.1 0.18 10.9 0.0 2.7 2 1 1 3 3 3 0 RmuC family GARP PF16731.5 KFH42919.1 - 0.08 12.6 5.3 1.3 8.6 0.1 2.7 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma GAS PF13851.6 KFH42919.1 - 0.11 11.8 1.5 0.4 10.0 1.5 1.9 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SMBP PF16785.5 KFH42919.1 - 0.25 11.6 2.6 0.36 11.1 1.1 2.0 2 1 1 3 3 3 0 Small metal-binding protein Dynactin_p22 PF07426.11 KFH42919.1 - 0.32 10.8 3.9 9.3 6.1 0.3 2.7 2 0 0 2 2 2 0 Dynactin subunit p22 TPR_MLP1_2 PF07926.12 KFH42919.1 - 1.8 8.6 7.5 3 7.9 0.8 3.3 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Histone PF00125.24 KFH42920.1 - 2.2e-21 76.6 2.4 2.8e-21 76.2 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFH42920.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFH42920.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KFH42920.1 - 0.026 14.2 0.1 0.061 13.0 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Pyr_redox_2 PF07992.14 KFH42921.1 - 1.3e-66 224.9 6.9 1.9e-66 224.3 6.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFH42921.1 - 7.7e-40 135.6 0.2 4.8e-39 133.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFH42921.1 - 4.3e-24 84.9 10.5 2.3e-21 76.1 0.8 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH42921.1 - 7.9e-11 42.0 4.5 2.1e-06 27.9 0.6 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFH42921.1 - 2.1e-09 37.2 10.8 7e-09 35.5 0.6 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH42921.1 - 4.3e-09 35.9 10.9 7.5e-07 28.6 3.7 3.3 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 KFH42921.1 - 4.8e-08 32.6 3.5 0.0022 17.4 0.5 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFH42921.1 - 2.6e-07 30.1 14.4 5.1e-06 25.8 5.2 3.1 2 2 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 KFH42921.1 - 1.9e-06 26.9 14.8 0.00013 20.8 2.2 4.0 4 0 0 4 4 4 3 HI0933-like protein DAO PF01266.24 KFH42921.1 - 3.5e-06 26.9 13.6 0.0015 18.2 0.3 3.8 4 0 0 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.17 KFH42921.1 - 4.3e-06 26.1 3.3 5e-05 22.7 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KFH42921.1 - 7.8e-05 22.1 7.0 0.0082 15.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFH42921.1 - 0.00066 20.1 1.8 0.17 12.3 0.3 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KFH42921.1 - 0.0025 17.1 8.7 0.22 10.7 0.9 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFH42921.1 - 0.0026 16.9 5.7 0.019 14.0 0.6 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 KFH42921.1 - 0.0092 15.1 0.6 3.4 6.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFH42921.1 - 0.0095 15.8 3.0 0.078 12.8 0.4 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KFH42921.1 - 0.22 9.9 1.6 0.23 9.8 0.6 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KFH42921.1 - 2 7.2 9.3 0.1 11.4 1.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DnaJ PF00226.31 KFH42922.1 - 1.5e-21 76.3 2.7 1.5e-21 76.3 2.7 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KFH42922.1 - 9.3e-19 66.4 0.5 0.00017 21.2 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFH42922.1 - 1.2e-18 67.1 0.3 1.2e-05 25.4 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH42922.1 - 8.5e-18 63.0 8.4 0.0021 18.0 0.2 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFH42922.1 - 5.6e-16 57.3 0.1 0.005 16.9 0.1 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFH42922.1 - 1.3e-13 50.3 3.5 0.0019 18.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH42922.1 - 1.5e-13 50.3 10.6 0.0094 16.7 0.0 8.0 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH42922.1 - 1.8e-10 40.3 4.5 0.024 14.3 0.1 5.7 4 2 2 6 6 6 4 TPR repeat TPR_19 PF14559.6 KFH42922.1 - 8.8e-10 39.0 6.3 0.0085 16.6 0.1 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH42922.1 - 1.5e-09 38.4 8.0 0.052 14.2 0.1 5.6 2 1 4 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH42922.1 - 1.8e-06 28.1 8.7 1.4 9.2 0.0 5.3 2 2 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFH42922.1 - 2.3e-05 24.7 9.0 7.7 7.4 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFH42922.1 - 5.2e-05 23.0 7.7 0.16 12.0 0.1 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KFH42922.1 - 0.00023 20.0 0.2 0.012 14.4 0.0 2.9 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 KFH42922.1 - 0.0013 19.0 14.0 0.025 14.9 0.4 5.3 4 3 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 KFH42922.1 - 0.014 15.8 6.6 2.2 8.7 0.0 4.5 2 1 3 5 5 5 0 Bacterial transcriptional activator domain PPTA PF01239.22 KFH42922.1 - 0.033 13.9 0.1 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_4 PF07721.14 KFH42922.1 - 0.041 14.5 5.6 20 6.2 3.9 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFH42922.1 - 0.074 12.7 0.0 9.2 5.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF1217 PF06748.12 KFH42922.1 - 0.17 11.9 2.2 0.51 10.4 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Alkyl_sulf_dimr PF14863.6 KFH42922.1 - 0.39 11.2 3.9 9.2 6.7 0.2 3.7 5 0 0 5 5 3 0 Alkyl sulfatase dimerisation Alpha-2-MRAP_N PF06400.11 KFH42922.1 - 0.96 9.5 9.3 0.022 14.7 2.4 1.8 3 0 0 3 3 1 0 Alpha-2-macroglobulin RAP, N-terminal domain TPR_10 PF13374.6 KFH42922.1 - 2.6 8.0 14.1 3.4 7.7 0.0 5.8 8 0 0 8 8 8 0 Tetratricopeptide repeat THUMP PF02926.17 KFH42923.1 - 4.7e-07 30.0 0.3 0.00044 20.4 0.1 2.3 2 0 0 2 2 2 2 THUMP domain Hemerythrin PF01814.23 KFH42924.1 - 0.017 15.8 0.0 0.043 14.4 0.0 1.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain NDT80_PhoG PF05224.12 KFH42925.1 - 2.5e-41 141.9 0.0 3.8e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family TSC21 PF15217.6 KFH42925.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TSC21 family SelP_N PF04592.14 KFH42925.1 - 0.47 9.8 10.1 0.98 8.8 10.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NMO PF03060.15 KFH42927.1 - 2.8e-57 194.6 0.4 3.6e-57 194.2 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFH42927.1 - 3.7e-10 39.3 0.1 1.3e-09 37.5 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFH42927.1 - 3e-05 23.2 3.4 4.8e-05 22.5 3.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KFH42927.1 - 0.016 14.5 0.2 0.024 13.8 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KFH42927.1 - 0.09 11.9 0.2 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.14 KFH42927.1 - 0.091 11.9 0.1 0.25 10.5 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF4240 PF14024.6 KFH42927.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Abhydrolase_1 PF00561.20 KFH42929.1 - 8e-20 71.5 0.0 3.9e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH42929.1 - 9e-15 55.9 1.7 9e-15 55.9 1.7 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH42929.1 - 3.9e-14 52.5 0.0 1.6e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFH42929.1 - 0.00012 21.6 0.0 0.00037 19.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KFH42929.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KFH42929.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KFH42929.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KFH42929.1 - 0.033 14.0 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KFH42929.1 - 0.054 13.2 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KFH42929.1 - 0.086 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KFH42929.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFH42929.1 - 0.13 12.1 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KFH42929.1 - 0.16 12.1 0.1 0.41 10.7 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain DAGK_cat PF00781.24 KFH42930.1 - 3.5e-06 26.6 0.0 9.1e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Methyltransf_33 PF10017.9 KFH42931.1 - 6e-35 120.9 0.0 7e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent eIF3g PF12353.8 KFH42933.1 - 4.3e-44 149.9 6.2 6.9e-44 149.2 6.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KFH42933.1 - 3e-16 59.0 0.1 7.3e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KFH42933.1 - 0.019 15.3 0.2 0.038 14.3 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Trypan_PARP PF05887.11 KFH42934.1 - 0.13 12.2 8.4 0.61 10.1 8.4 2.1 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Med3 PF11593.8 KFH42934.1 - 0.75 8.9 10.5 1.1 8.4 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3435 PF11917.8 KFH42935.1 - 1.1e-07 31.2 0.0 4.3e-06 25.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) TRM PF02005.16 KFH42936.1 - 3.6e-104 348.9 0.0 3e-93 313.0 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase zf-NADH-PPase PF09297.11 KFH42936.1 - 0.015 14.9 0.7 0.038 13.7 0.7 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KFH42936.1 - 0.1 12.3 0.8 0.24 11.2 0.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Methyltransf_25 PF13649.6 KFH42936.1 - 0.12 13.1 0.4 0.29 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFH42936.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain UPF0547 PF10571.9 KFH42936.1 - 0.19 11.8 1.0 0.39 10.8 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TIM21 PF08294.11 KFH42937.1 - 6.1e-38 130.0 0.1 6.5e-36 123.4 0.1 2.1 1 1 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFH42937.1 - 4.6e-05 23.1 0.0 0.00012 21.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 120_Rick_ant PF12574.8 KFH42938.1 - 0.17 11.0 0.1 0.24 10.6 0.1 1.1 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen zf-C2H2 PF00096.26 KFH42939.1 - 7.6e-08 32.4 13.8 0.0015 18.9 4.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH42939.1 - 1.3e-06 28.6 25.7 2e-05 24.8 3.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH42939.1 - 0.00016 22.2 11.8 0.065 14.1 3.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFH42939.1 - 0.051 14.2 1.3 0.051 14.2 1.3 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFH42939.1 - 0.083 13.2 3.2 0.27 11.6 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFH42939.1 - 0.11 12.6 2.5 5.8 7.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 KFH42939.1 - 0.49 10.1 0.9 1 9.1 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF676 PF05057.14 KFH42940.1 - 4.1e-43 147.4 0.0 6.1e-28 97.8 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Cwf_Cwc_15 PF04889.12 KFH42940.1 - 0.032 14.0 8.8 0.068 12.9 8.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KFH42940.1 - 0.29 11.5 5.3 0.78 10.2 5.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIE-A_C PF11521.8 KFH42940.1 - 0.71 10.2 8.7 2.8 8.3 8.7 2.0 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Pox_Ag35 PF03286.14 KFH42940.1 - 5.6 6.7 12.8 1.1 9.0 7.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 KFH42940.1 - 8.3 7.2 13.7 45 4.8 13.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 KFH42940.1 - 8.6 5.6 8.9 14 4.9 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein Lactonase PF10282.9 KFH42942.1 - 4.3e-83 279.4 0.0 5.1e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pterin_bind PF00809.22 KFH42943.1 - 6.9e-81 271.5 0.0 1e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KFH42943.1 - 3.9e-37 127.2 0.0 7.7e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Ribosomal_L7Ae PF01248.26 KFH42945.1 - 1.2e-21 76.2 0.1 1.5e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFH42945.1 - 0.0059 16.7 0.0 0.007 16.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFH42945.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain ArfGap PF01412.18 KFH42946.1 - 1.5e-35 121.8 0.4 2.6e-35 121.0 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.8 KFH42946.1 - 3.9 7.4 7.1 0.19 11.7 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) Pkinase PF00069.25 KFH42947.1 - 1.4e-30 106.5 0.0 1.5e-17 63.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42947.1 - 2.2e-13 50.1 0.0 4e-05 23.0 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KFH42947.1 - 0.0044 17.0 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH42947.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFH42947.1 - 0.019 14.3 0.0 0.79 9.0 0.0 2.8 3 0 0 3 3 3 0 Kinase-like ABC_tran PF00005.27 KFH42948.1 - 9.7e-45 152.4 3.4 1.4e-21 77.4 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KFH42948.1 - 4.9e-13 49.5 8.2 0.0015 18.4 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KFH42948.1 - 2.3e-09 37.1 3.8 6.4e-09 35.7 3.8 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFH42948.1 - 3.9e-08 33.0 0.1 0.048 13.1 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH42948.1 - 1.1e-07 31.5 0.4 0.00085 19.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFH42948.1 - 5.3e-07 29.7 0.1 0.039 14.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KFH42948.1 - 7.2e-06 26.3 0.4 0.0068 16.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KFH42948.1 - 7.6e-06 25.1 1.1 0.013 14.5 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFH42948.1 - 9.8e-06 25.4 0.4 0.19 11.4 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KFH42948.1 - 2.2e-05 25.0 0.1 0.25 11.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH42948.1 - 4.9e-05 23.3 3.1 0.09 12.7 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KFH42948.1 - 6.7e-05 23.2 0.6 0.28 11.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KFH42948.1 - 8.5e-05 23.1 9.6 0.04 14.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KFH42948.1 - 0.0001 22.7 2.0 0.42 11.0 0.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KFH42948.1 - 0.00022 21.4 0.7 1.1 9.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KFH42948.1 - 0.00029 20.9 0.9 0.26 11.3 0.0 3.0 4 0 0 4 4 2 1 Dynamin family DUF87 PF01935.17 KFH42948.1 - 0.00044 20.4 4.1 0.26 11.3 0.1 3.1 3 0 0 3 3 3 2 Helicase HerA, central domain AAA PF00004.29 KFH42948.1 - 0.00057 20.3 0.1 0.088 13.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFH42948.1 - 0.00091 19.2 0.3 0.11 12.5 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.13 KFH42948.1 - 0.0039 16.4 0.2 0.61 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFH42948.1 - 0.005 16.6 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KFH42948.1 - 0.0059 16.3 0.2 3.8 7.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 KFH42948.1 - 0.0071 16.1 2.8 0.037 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain NTPase_1 PF03266.15 KFH42948.1 - 0.0084 16.0 0.1 2 8.3 0.0 2.9 3 0 0 3 3 3 1 NTPase Arf PF00025.21 KFH42948.1 - 0.0085 15.6 0.6 0.38 10.2 0.1 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFH42948.1 - 0.0091 16.4 0.1 0.94 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.17 KFH42948.1 - 0.0096 15.6 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.6 KFH42948.1 - 0.0097 15.9 0.3 7.6 6.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 KFH42948.1 - 0.011 15.0 1.0 1.2 8.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KFH42948.1 - 0.017 14.4 0.2 5.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 KFH42948.1 - 0.028 14.0 4.0 0.13 11.8 0.0 2.9 4 0 0 4 4 2 0 AAA domain MobB PF03205.14 KFH42948.1 - 0.037 13.9 0.3 13 5.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KFH42948.1 - 0.039 13.5 0.3 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KFH42948.1 - 0.042 14.1 0.6 14 5.9 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KFH42948.1 - 0.056 13.0 1.0 1.9 8.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KFH42948.1 - 0.063 13.3 0.6 3.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFH42948.1 - 0.086 12.8 0.4 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFH42948.1 - 0.2 11.3 0.1 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KFH42948.1 - 0.35 10.4 1.7 15 5.1 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KFH42948.1 - 0.38 9.4 6.6 6.2 5.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KFH42948.1 - 0.67 10.4 7.7 9.6 6.6 0.1 3.9 4 2 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 KFH42948.1 - 0.94 9.3 3.4 14 5.5 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea DUF4011 PF13195.6 KFH42948.1 - 3.7 7.4 6.4 25 4.8 2.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4011) Spo7 PF03907.13 KFH42949.1 - 9e-92 306.5 0.1 1.4e-91 305.9 0.1 1.3 1 0 0 1 1 1 1 Spo7-like protein Na_H_Exchanger PF00999.21 KFH42949.1 - 0.065 12.0 0.2 0.091 11.5 0.2 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Macoilin PF09726.9 KFH42949.1 - 1.6 7.2 7.1 2.1 6.8 7.1 1.1 1 0 0 1 1 1 0 Macoilin family RSN1_7TM PF02714.15 KFH42950.1 - 1e-75 254.6 24.2 1e-75 254.6 24.2 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFH42950.1 - 2.8e-43 147.4 2.4 2.8e-43 147.4 2.4 3.3 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFH42950.1 - 2.7e-33 115.6 0.1 5.4e-19 69.1 0.1 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFH42950.1 - 5.2e-16 58.6 0.0 1.7e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3040 PF11239.8 KFH42950.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) DUF373 PF04123.13 KFH42950.1 - 0.6 9.5 6.2 2 7.8 6.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Bromodomain PF00439.25 KFH42951.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 KFH42951.1 - 8.6e-06 26.0 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MerE PF05052.12 KFH42952.1 - 0.011 15.6 0.2 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 MerE protein CYSTM PF12734.7 KFH42952.1 - 0.043 14.1 41.7 2.4e+02 2.1 41.7 3.7 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF3391 PF11871.8 KFH42954.1 - 1 9.9 7.6 0.13 12.8 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Glyco_trans_1_2 PF13524.6 KFH42954.1 - 9.9 6.6 9.2 5.4 7.5 2.0 2.1 1 1 1 2 2 2 0 Glycosyl transferases group 1 MARVEL PF01284.23 KFH42955.1 - 4.2e-06 26.8 11.4 4.6e-05 23.5 10.4 2.0 1 1 1 2 2 2 1 Membrane-associating domain Yip1 PF04893.17 KFH42955.1 - 0.0018 18.0 4.8 0.0025 17.6 4.8 1.1 1 0 0 1 1 1 1 Yip1 domain VIT1 PF01988.19 KFH42955.1 - 0.11 12.4 3.6 0.23 11.3 3.3 1.5 1 1 0 1 1 1 0 VIT family Pkinase PF00069.25 KFH42956.1 - 7.3e-30 104.2 0.0 2.6e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH42956.1 - 1.5e-08 34.2 0.0 7.1e-05 22.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Rad51 PF08423.11 KFH42957.1 - 4.8e-10 39.1 0.0 7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFH42957.1 - 0.0087 15.6 0.3 0.05 13.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.15 KFH42957.1 - 0.012 15.0 0.1 0.26 10.6 0.1 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_11 PF13086.6 KFH42957.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFH42957.1 - 0.014 15.8 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFH42957.1 - 0.032 13.6 0.6 0.051 12.9 0.1 1.5 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 KFH42957.1 - 0.062 13.6 0.1 0.27 11.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain CKAP2_C PF15297.6 KFH42957.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RecA PF00154.21 KFH42957.1 - 0.15 11.5 0.2 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Fringe PF02434.16 KFH42959.1 - 0.0036 16.8 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF4710 PF15828.5 KFH42959.1 - 1.8 8.8 5.0 3.4 7.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Zn_clus PF00172.18 KFH42960.1 - 1.9e-09 37.5 8.4 1.9e-09 37.5 8.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH42960.1 - 8e-05 21.8 0.1 0.00013 21.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OS-D PF03392.13 KFH42960.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D PEMT PF04191.13 KFH42962.1 - 3.8e-58 194.4 8.0 1.3e-35 122.0 0.8 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KFH42962.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KFH42962.1 - 0.045 14.3 0.1 1.2 9.7 0.1 2.3 1 1 0 1 1 1 0 SKICH domain TBCA PF02970.16 KFH42963.1 - 1.4e-22 79.8 7.5 3e-22 78.7 6.8 1.7 1 1 1 2 2 2 1 Tubulin binding cofactor A DUF2408 PF10303.9 KFH42963.1 - 0.0044 17.6 0.7 0.0049 17.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) ETC_C1_NDUFA5 PF04716.14 KFH42963.1 - 0.023 14.5 1.6 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 ETC complex I subunit conserved region Far-17a_AIG1 PF04750.14 KFH42964.1 - 2.5e-46 157.6 16.8 2.8e-46 157.4 16.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein CPP1-like PF11833.8 KFH42964.1 - 0.28 10.8 2.0 0.53 9.9 2.0 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Claudin_2 PF13903.6 KFH42964.1 - 2.3 7.9 9.1 0.88 9.3 3.4 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Hexokinase_2 PF03727.16 KFH42965.1 - 4.4e-83 278.4 0.0 6.1e-83 277.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFH42965.1 - 3.8e-71 239.1 0.0 8.3e-71 238.0 0.0 1.5 2 0 0 2 2 2 1 Hexokinase SKIP_SNW PF02731.15 KFH42966.1 - 0.038 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 SKIP/SNW domain WD40 PF00400.32 KFH42968.1 - 3e-05 24.7 0.0 5.1 8.1 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH42968.1 - 4.7e-05 23.6 0.0 0.087 13.1 0.0 4.4 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFH42968.1 - 0.00014 21.7 0.0 0.0046 16.9 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat MCM PF00493.23 KFH42970.1 - 6.1e-101 336.2 0.0 8.6e-101 335.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFH42970.1 - 1.5e-40 138.0 1.1 3e-40 137.0 1.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFH42970.1 - 1.8e-28 98.8 2.0 4.6e-28 97.5 2.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFH42970.1 - 7.1e-16 58.7 0.5 2.1e-15 57.2 0.5 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH42970.1 - 2.2e-05 23.9 0.0 0.00048 19.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFH42970.1 - 3.2e-05 23.9 0.0 0.00014 21.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFH42970.1 - 0.0026 17.6 0.0 0.0084 16.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 KFH42970.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 GGA N-GAT domain CDC45 PF02724.14 KFH42971.1 - 2.9 6.1 7.4 3.4 5.9 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 KFH42971.1 - 7 5.2 10.5 9.8 4.7 10.5 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Glycoprotein PF03409.15 KFH42972.1 - 0.54 9.0 15.2 0.78 8.5 15.2 1.3 1 0 0 1 1 1 0 Transmembrane glycoprotein CEND1 PF15677.5 KFH42972.1 - 0.88 10.1 8.2 1.5 9.4 8.2 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Plasmodium_Vir PF05795.11 KFH42972.1 - 1.8 7.9 4.7 2.2 7.6 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 KFH42972.1 - 2 6.7 4.7 2.4 6.4 4.7 1.0 1 0 0 1 1 1 0 Menin Med13_C PF06333.12 KFH42972.1 - 2.2 7.5 12.5 2.8 7.1 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Mucin PF01456.17 KFH42972.1 - 3.1 7.8 38.0 3.4 7.6 37.3 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein VTC PF09359.10 KFH42973.1 - 7.7e-100 333.8 0.1 1.3e-99 333.0 0.1 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KFH42973.1 - 7.7e-13 48.7 1.0 7.7e-13 48.7 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KFH42973.1 - 2.5e-12 47.4 6.4 1.1e-05 25.6 0.0 4.1 3 1 1 4 4 4 2 SPX domain Fe_dep_repress PF01325.19 KFH42973.1 - 0.0024 18.0 0.1 0.0049 17.0 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KFH42973.1 - 0.013 15.4 0.2 0.042 13.7 0.2 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KFH42973.1 - 0.048 13.7 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix LysE PF01810.18 KFH42973.1 - 0.11 11.9 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 LysE type translocator FixQ PF05545.11 KFH42973.1 - 0.11 12.4 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Leo1 PF04004.13 KFH42975.1 - 2.8e-35 121.6 0.0 4.6e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF3042 PF11240.8 KFH42975.1 - 0.054 13.5 3.5 0.16 12.0 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Sua5_yciO_yrdC PF01300.18 KFH42976.1 - 5.7e-51 172.6 0.0 8.3e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KFH42976.1 - 2e-30 106.1 0.0 3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding F-box PF00646.33 KFH42978.1 - 0.00018 21.3 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.22 KFH42979.1 - 2.8e-135 451.4 0.1 3.7e-135 451.0 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPX PF03105.19 KFH42980.1 - 1.1 9.1 8.3 1.3 8.9 8.3 1.1 1 0 0 1 1 1 0 SPX domain CobT PF06213.12 KFH42980.1 - 2.3 7.5 13.3 3 7.1 13.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 KFH42980.1 - 3.5 6.9 14.3 3.7 6.8 14.3 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 KFH42980.1 - 4.5 6.0 7.9 5.6 5.7 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rad21_Rec8_N PF04825.13 KFH42981.1 - 4.4e-37 126.6 0.1 1.8e-36 124.6 0.1 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFH42981.1 - 6.2e-09 35.0 0.0 1.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Aldolase_II PF00596.21 KFH42982.1 - 3.9e-43 147.6 0.0 4.7e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-C2H2 PF00096.26 KFH42983.1 - 2.8e-06 27.5 8.5 9.3e-06 25.8 0.5 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFH42983.1 - 3.7e-06 26.8 0.7 0.01 15.8 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH42983.1 - 5e-06 26.7 1.3 5e-06 26.7 1.3 3.6 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KFH42983.1 - 0.00029 21.4 4.4 0.24 12.1 0.0 2.7 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KFH42983.1 - 0.0038 18.0 0.4 0.0038 18.0 0.4 3.1 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFH42983.1 - 0.12 12.2 2.5 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFH42983.1 - 0.15 11.8 2.8 0.6 9.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFH42983.1 - 0.16 12.3 1.5 2.5 8.5 0.3 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding COG4 PF08318.12 KFH42984.1 - 4.8e-125 417.1 0.0 6.9e-125 416.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF294_C PF10335.9 KFH42984.1 - 0.2 11.4 0.6 0.44 10.3 0.6 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain MRP_L53 PF10780.9 KFH42985.1 - 1.2e-21 76.6 0.3 1.7e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sel1 PF08238.12 KFH42986.1 - 3.9e-12 46.4 14.1 7.8e-05 23.2 2.2 4.1 4 0 0 4 4 4 3 Sel1 repeat Pil1 PF13805.6 KFH42987.1 - 3e-107 358.0 1.2 3.8e-107 357.7 1.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Ank_2 PF12796.7 KFH42988.1 - 0.029 15.0 0.0 0.4 11.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) THOC7 PF05615.13 KFH42989.1 - 4.9e-42 143.3 6.6 4.9e-42 143.3 6.6 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 KFH42989.1 - 0.05 12.1 8.6 0.063 11.8 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 KFH42989.1 - 0.53 10.6 6.9 0.96 9.8 6.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pro_isomerase PF00160.21 KFH42990.1 - 1.7e-50 171.4 0.1 4e-50 170.2 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFH42990.1 - 4.1e-12 46.4 0.0 0.00072 20.3 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH42990.1 - 2.8e-05 24.3 0.0 0.011 16.0 0.0 3.5 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH42990.1 - 0.017 14.1 0.3 0.91 8.4 0.1 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribophorin_I PF04597.14 KFH42991.1 - 2.6e-148 494.9 0.0 3e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I SLD5_C PF16922.5 KFH42992.1 - 1.5e-14 53.9 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KFH42992.1 - 1.6e-08 35.0 0.1 5.9e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 GINS complex protein DUF896 PF05979.12 KFH42992.1 - 0.028 14.3 0.4 0.077 12.9 0.1 1.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Clat_adaptor_s PF01217.20 KFH42994.1 - 6.5e-17 61.8 0.8 6.4e-16 58.6 0.8 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain NT-C2 PF10358.9 KFH42995.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Cys_Met_Meta_PP PF01053.20 KFH42996.1 - 1.8e-29 102.5 0.0 2.4e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFH42996.1 - 5.5e-10 39.0 0.0 8.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Indigoidine_A PF04227.12 KFH42997.1 - 1.7e-110 369.0 0.5 2.4e-110 368.5 0.5 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KFH42997.1 - 5.2e-20 71.9 0.2 2.4e-11 43.5 0.0 2.9 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Mob1_phocein PF03637.17 KFH42998.1 - 6.5e-37 127.2 0.1 1.1e-36 126.5 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family MSA-2c PF12238.8 KFH42998.1 - 9.3 6.2 9.0 15 5.5 9.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3336 PF11815.8 KFH42999.1 - 1.1e-37 128.8 0.0 5.5e-36 123.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 KFH42999.1 - 1.9e-13 51.1 1.1 5.1e-13 49.7 0.2 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Oxidored_q2 PF00420.24 KFH43000.1 - 0.05 13.2 0.4 9 6.0 0.1 3.0 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L bZIP_1 PF00170.21 KFH43001.1 - 5.2e-10 39.3 15.2 1.2e-09 38.1 14.4 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KFH43001.1 - 1.1e-05 25.9 12.8 3e-05 24.4 12.8 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFH43001.1 - 1.2e-05 25.3 13.0 3.5e-05 23.8 13.0 1.9 1 0 0 1 1 1 1 Basic region leucine zipper FapA PF03961.13 KFH43001.1 - 0.012 14.2 4.4 0.017 13.7 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HeLo PF14479.6 KFH43001.1 - 0.013 15.3 4.2 0.025 14.4 4.2 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF4407 PF14362.6 KFH43001.1 - 0.085 12.2 2.6 0.13 11.6 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KFH43001.1 - 0.17 11.5 4.2 0.32 10.5 4.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit 5_nucleotid PF05761.14 KFH43001.1 - 0.93 8.3 6.5 2.3 7.0 6.5 1.6 1 0 0 1 1 1 0 5' nucleotidase family UPF0242 PF06785.11 KFH43001.1 - 1.3 9.1 14.4 2.4 8.2 14.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KFH43001.1 - 1.8 8.8 19.3 3.2 8.0 18.3 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KFH43001.1 - 5.2 7.8 9.0 18 6.1 0.0 3.5 1 1 2 3 3 3 0 SlyX adh_short PF00106.25 KFH43002.1 - 1e-42 145.9 0.4 1.7e-42 145.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH43002.1 - 4.4e-29 101.7 0.1 5.9e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH43002.1 - 2.1e-08 34.3 6.4 4e-07 30.1 6.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH43002.1 - 5.5e-08 32.6 0.4 1e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH43002.1 - 0.0011 18.0 0.3 0.0016 17.5 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFH43002.1 - 0.0029 16.8 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Urocanase PF01175.18 KFH43002.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain GDP_Man_Dehyd PF16363.5 KFH43002.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KFH43002.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFH43002.1 - 0.05 13.5 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF3216 PF11505.8 KFH43002.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) NAD_binding_3 PF03447.16 KFH43002.1 - 0.083 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PALP PF00291.25 KFH43002.1 - 0.092 12.1 0.8 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ApbA PF02558.16 KFH43002.1 - 0.12 12.0 0.6 3 7.5 0.2 2.5 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Calreticulin PF00262.18 KFH43003.1 - 2.9e-168 559.4 19.6 4e-168 559.0 19.6 1.2 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.13 KFH43003.1 - 2.4 8.8 6.6 0.62 10.7 1.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain E1-E2_ATPase PF00122.20 KFH43004.1 - 5e-46 156.5 0.3 5e-46 156.5 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH43004.1 - 2.3e-42 144.8 1.6 4.6e-42 143.8 1.6 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFH43004.1 - 2.8e-20 73.5 2.7 7.6e-19 68.8 2.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH43004.1 - 6.7e-18 64.2 0.0 1.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFH43004.1 - 4.1e-12 46.0 0.0 8.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFH43004.1 - 3.8e-05 23.6 1.0 0.00051 19.9 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KFH43005.1 - 2.2e-36 125.1 0.1 3.1e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH43005.1 - 5.2e-29 101.4 0.1 6.6e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH43005.1 - 1e-12 48.4 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF4439 PF14530.6 KFH43005.1 - 0.0069 17.1 0.1 0.015 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) NAD_binding_10 PF13460.6 KFH43005.1 - 0.015 15.2 0.6 0.024 14.5 0.5 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFH43005.1 - 0.071 13.4 0.2 0.17 12.2 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 KFH43005.1 - 0.071 12.5 0.0 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Tannase PF07519.11 KFH43006.1 - 2.7e-100 336.5 1.2 3.2e-100 336.3 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KFH43006.1 - 0.00089 18.6 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFH43006.1 - 0.0025 17.3 0.1 0.39 10.1 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFH43006.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fumarate_red_D PF02313.17 KFH43006.1 - 0.055 13.6 0.1 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2607 PF10795.9 KFH43006.1 - 2.1 8.5 7.9 4.7 7.4 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Sec20 PF03908.13 KFH43007.1 - 4.2e-15 55.4 1.9 5.7e-15 55.0 0.5 1.9 2 0 0 2 2 2 1 Sec20 BRE1 PF08647.11 KFH43007.1 - 0.12 12.4 7.6 0.46 10.6 0.6 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3391 PF11871.8 KFH43007.1 - 0.79 10.3 6.8 0.9 10.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) T2SSF PF00482.23 KFH43007.1 - 6.4 6.8 7.3 0.56 10.2 0.8 2.4 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F CCDC-167 PF15188.6 KFH43007.1 - 6.4 7.2 7.8 38 4.7 4.7 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DAHP_synth_1 PF00793.20 KFH43008.1 - 1.1e-100 336.0 0.1 1.4e-100 335.7 0.1 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.24 KFH43009.1 - 2.5e-12 46.4 31.7 2.5e-06 27.2 1.3 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFH43009.1 - 8.4e-09 35.2 31.7 0.00024 21.0 1.3 5.6 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 KFH43009.1 - 1.2e-05 25.0 5.6 0.0023 17.7 0.2 3.9 5 0 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KFH43009.1 - 0.00017 22.3 23.9 0.07 13.8 0.4 4.7 1 1 3 4 4 4 4 Torus domain zf-CCCH_3 PF15663.5 KFH43009.1 - 0.13 12.5 16.5 0.04 14.1 5.8 3.0 1 1 1 2 2 2 0 Zinc-finger containing family SDA1 PF05285.12 KFH43009.1 - 9.5 5.5 11.6 0.6 9.5 5.7 1.7 2 0 0 2 2 2 0 SDA1 Pyrophosphatase PF00719.19 KFH43010.1 - 6.6e-58 195.0 0.1 8.8e-58 194.6 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase p450 PF00067.22 KFH43011.1 - 2.1e-67 227.9 0.0 2.7e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5308 PF17233.2 KFH43012.1 - 0.00017 21.9 3.0 0.00031 21.0 3.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Kei1 PF08552.11 KFH43012.1 - 0.54 10.1 4.6 0.91 9.4 4.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Mucin PF01456.17 KFH43012.1 - 2.1 8.3 34.6 0.24 11.4 29.7 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein TMEM154 PF15102.6 KFH43012.1 - 2.6 7.9 8.2 4.8 7.1 8.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family FSA_C PF10479.9 KFH43012.1 - 3.2 5.8 14.9 3.9 5.5 14.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mannitol_dh_C PF08125.13 KFH43014.1 - 1.8e-40 139.0 0.0 2.8e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KFH43014.1 - 2.3e-18 66.8 0.1 9.6e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KFH43014.1 - 0.0019 17.8 0.5 0.014 15.0 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH43014.1 - 0.051 13.8 0.4 1.9 8.8 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFH43014.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pkinase_C PF00433.24 KFH43017.1 - 4.7e-13 49.6 2.9 5.5e-13 49.4 1.4 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase PF00069.25 KFH43018.1 - 2.7e-06 27.0 0.0 0.043 13.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Cytokin-bind PF09265.10 KFH43018.1 - 0.14 11.5 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RSN1_7TM PF02714.15 KFH43020.1 - 1.3e-83 280.5 26.0 3.6e-83 279.0 26.0 1.8 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFH43020.1 - 1.3e-43 148.5 3.9 1.3e-43 148.5 3.9 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFH43020.1 - 1e-38 133.3 0.4 1.5e-38 132.8 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFH43020.1 - 8.8e-35 118.8 0.3 2.1e-34 117.6 0.3 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 KFH43020.1 - 0.083 13.2 3.4 0.44 10.9 2.2 2.4 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A p450 PF00067.22 KFH43021.1 - 1.7e-60 205.1 0.0 2.2e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KFH43023.1 - 2.2e-42 144.7 0.0 2.5e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SKG6 PF08693.10 KFH43024.1 - 0.0057 16.0 0.3 0.015 14.7 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM100 PF16311.5 KFH43024.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Caskin-Pro-rich PF16907.5 KFH43024.1 - 0.071 13.6 3.5 0.38 11.3 3.5 2.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins adh_short PF00106.25 KFH43025.1 - 5.1e-40 137.0 3.8 7.6e-40 136.5 3.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH43025.1 - 1.4e-36 126.3 3.6 1.8e-36 125.9 3.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH43025.1 - 7.2e-07 29.3 0.8 1e-06 28.8 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH43025.1 - 0.057 13.3 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFH43025.1 - 0.1 12.9 0.4 0.29 11.4 0.3 1.9 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain WSC PF01822.19 KFH43026.1 - 1.4e-10 41.2 5.9 3.1e-10 40.1 5.9 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.11 KFH43026.1 - 7.6e-05 22.9 1.6 0.00014 22.0 1.6 1.4 1 0 0 1 1 1 1 Podoplanin CD99L2 PF12301.8 KFH43026.1 - 0.00041 20.7 0.9 0.00083 19.7 0.9 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 SKG6 PF08693.10 KFH43026.1 - 0.01 15.2 7.7 0.025 14.0 7.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FPV060 PF17614.2 KFH43026.1 - 0.036 13.5 1.6 0.074 12.4 1.5 1.4 1 1 0 1 1 1 0 Viral CC-type chemokine Gram_pos_anchor PF00746.21 KFH43026.1 - 0.05 13.5 0.6 0.05 13.5 0.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 KFH43026.1 - 0.15 12.9 0.0 0.33 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3042 PF11240.8 KFH43026.1 - 0.17 12.0 1.6 0.36 10.9 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF4690 PF15756.5 KFH43026.1 - 9.2 7.0 13.1 0.25 12.0 3.8 2.5 1 1 1 2 2 2 0 Small Novel Rich in Cartilage Tyrosinase PF00264.20 KFH43027.1 - 7.2e-35 121.3 0.6 1.1e-34 120.7 0.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_1 PF00561.20 KFH43028.1 - 7.8e-49 166.6 0.0 1.3e-48 165.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH43028.1 - 0.0035 18.0 3.4 0.016 15.8 3.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arf PF00025.21 KFH43029.1 - 2.3e-42 144.4 0.0 2.6e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFH43029.1 - 2.6e-18 66.1 0.0 3e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH43029.1 - 1.9e-15 57.2 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFH43029.1 - 4.4e-07 29.5 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFH43029.1 - 1.3e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFH43029.1 - 1.2e-05 24.8 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFH43029.1 - 1.2e-05 24.6 0.2 4.7e-05 22.7 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KFH43029.1 - 0.041 13.4 0.4 0.11 12.0 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFH43029.1 - 0.045 13.8 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KFH43029.1 - 0.052 13.6 0.0 0.49 10.4 0.1 2.0 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KFH43029.1 - 0.054 13.3 0.0 0.076 12.8 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 KFH43031.1 - 1.2e-13 50.8 46.5 6.1e-13 48.4 46.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Fst_toxin PF13955.6 KFH43031.1 - 2.1 8.3 8.3 1.6 8.8 1.3 3.2 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Transferase PF02458.15 KFH43032.1 - 1.8e-23 82.9 0.0 1.2e-14 53.9 0.0 2.9 2 1 0 2 2 2 2 Transferase family Coatomer_WDAD PF04053.14 KFH43033.1 - 1.8e-173 577.7 0.0 3.2e-173 576.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFH43033.1 - 1e-38 130.6 8.7 1.5e-06 28.8 0.0 9.2 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43033.1 - 1e-07 32.2 0.0 3.5 8.0 0.0 6.0 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH43033.1 - 2.6e-06 26.4 1.5 0.023 13.4 0.1 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 MetallophosC PF16370.5 KFH43033.1 - 0.065 13.5 0.1 0.27 11.5 0.0 1.9 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase BBS2_Mid PF14783.6 KFH43033.1 - 0.07 13.2 0.0 7.3 6.7 0.0 3.5 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Peripla_BP_6 PF13458.6 KFH43033.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein CBP PF12192.8 KFH43034.1 - 8.6e-07 29.1 3.7 8.6e-07 29.1 3.7 1.9 1 1 1 2 2 2 1 Fungal calcium binding protein Radical_SAM PF04055.21 KFH43035.1 - 2.2e-09 37.9 0.0 3.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFH43035.1 - 0.00029 21.1 0.0 0.00046 20.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFH43035.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain PGI PF00342.19 KFH43036.1 - 2.3e-226 752.1 0.1 2.7e-226 751.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FTA2 PF13095.6 KFH43037.1 - 9.8e-58 195.3 0.0 1.7e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Aldedh PF00171.22 KFH43038.1 - 2.6e-144 481.2 0.0 3e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Evr1_Alr PF04777.13 KFH43039.1 - 1.4e-26 92.9 0.0 2e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KFH43039.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 SQHop_cyclase_C PF13243.6 KFH43040.1 - 1.3e-50 172.3 0.0 1.1e-44 152.9 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFH43040.1 - 5.5e-41 140.6 0.3 1.5e-34 119.4 0.1 3.9 4 1 1 5 5 5 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KFH43040.1 - 1.1e-24 85.9 5.6 2.4e-06 27.2 0.0 6.4 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KFH43040.1 - 0.00078 18.6 0.0 0.013 14.5 0.0 3.0 2 1 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KFH43040.1 - 0.0012 18.2 0.0 0.23 10.8 0.0 3.6 4 0 0 4 4 4 1 Pectic acid lyase PI-PLC-X PF00388.19 KFH43042.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain p450 PF00067.22 KFH43043.1 - 5.9e-68 229.7 0.0 7.3e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 THOC2_N PF16134.5 KFH43044.1 - 8.3e-236 784.5 0.0 1.2e-235 784.0 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KFH43044.1 - 1.1e-95 320.4 0.0 2.1e-95 319.4 0.0 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KFH43044.1 - 3.9e-28 97.3 0.1 9.1e-28 96.1 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit OAD_gamma PF04277.13 KFH43044.1 - 1.2 9.7 5.3 0.58 10.8 0.1 3.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cyclin PF08613.11 KFH43045.1 - 6.1e-42 143.7 3.3 2.2e-24 86.7 0.1 2.5 2 1 0 2 2 2 2 Cyclin Cwf_Cwc_15 PF04889.12 KFH43045.1 - 0.011 15.4 0.9 0.02 14.6 0.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sugar_tr PF00083.24 KFH43046.1 - 1.1e-47 163.0 1.0 1.7e-47 162.3 1.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH43046.1 - 4e-23 81.9 26.8 4.3e-23 81.8 25.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH43046.1 - 0.046 12.6 6.4 0.11 11.3 1.4 2.3 2 0 0 2 2 2 0 MFS_1 like family RNA_pol_Rpb2_6 PF00562.28 KFH43047.1 - 6.9e-114 380.9 0.0 9e-114 380.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFH43047.1 - 1.6e-35 122.5 0.0 2.4e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KFH43047.1 - 7.9e-28 96.4 0.0 2.1e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KFH43047.1 - 1.9e-24 86.3 0.0 3.2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KFH43047.1 - 2.3e-24 85.1 0.0 4.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KFH43047.1 - 2.5e-16 59.8 0.0 9e-15 54.9 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Aldo_ket_red PF00248.21 KFH43048.1 - 3.4e-40 138.1 0.0 8.9e-40 136.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Polysacc_deac_1 PF01522.21 KFH43049.1 - 6.5e-32 110.0 0.0 1e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KFH43049.1 - 6.4e-08 32.9 14.4 1.1e-07 32.2 14.4 1.4 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 KFH43049.1 - 6.5e-05 22.7 0.1 9.7e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 KFH43049.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CPSF_A PF03178.15 KFH43050.1 - 4.5e-68 229.9 0.0 6.9e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Kinesin PF00225.23 KFH43051.1 - 1.8e-117 392.0 0.0 2.5e-117 391.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFH43051.1 - 6.7e-29 100.8 0.0 1.3e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KFH43051.1 - 0.0028 17.9 1.3 0.0028 17.9 1.3 2.0 2 0 0 2 2 2 1 Herpesvirus UL14-like protein AAA_33 PF13671.6 KFH43051.1 - 0.02 15.0 0.0 0.089 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF1977 PF09320.11 KFH43051.1 - 0.23 11.7 3.1 0.63 10.3 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) adh_short_C2 PF13561.6 KFH43052.1 - 8.7e-63 212.0 1.6 1e-62 211.8 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43052.1 - 6.9e-40 136.6 0.8 8.2e-40 136.4 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH43052.1 - 1.8e-13 50.8 0.5 2.6e-13 50.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.12 KFH43052.1 - 0.033 14.2 0.7 0.062 13.3 0.3 1.8 2 0 0 2 2 2 0 Restriction endonuclease ERO1 PF04137.15 KFH43053.1 - 1e-133 446.0 0.0 1.2e-133 445.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.9 KFH43054.1 - 9.4e-82 274.1 0.0 1.1e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein ER_lumen_recept PF00810.18 KFH43056.1 - 2.5e-43 148.4 6.2 4.4e-43 147.6 6.2 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2227 PF09988.9 KFH43056.1 - 0.19 11.6 2.7 0.32 10.9 2.3 1.6 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.14 KFH43056.1 - 0.57 10.0 0.0 0.57 10.0 0.0 3.0 3 1 0 3 3 3 0 PQ loop repeat IDO PF01231.18 KFH43057.1 - 1.1e-148 495.7 0.0 1.2e-148 495.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Vta1 PF04652.16 KFH43059.1 - 3.2e-48 163.4 3.6 3.3e-48 163.3 1.4 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFH43059.1 - 9.9e-18 63.6 0.2 3.5e-17 61.8 0.1 2.0 1 1 1 2 2 2 1 Vta1 C-terminal domain DUF3390 PF11870.8 KFH43059.1 - 0.097 13.1 1.2 20 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3390) ADK PF00406.22 KFH43060.1 - 3e-35 121.5 0.0 1e-19 71.1 0.1 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFH43060.1 - 1.4e-13 51.4 0.2 3.5e-11 43.7 0.1 2.6 3 0 0 3 3 3 1 AAA domain ADK_lid PF05191.14 KFH43060.1 - 7.1e-13 48.3 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFH43060.1 - 0.0047 17.5 0.0 0.046 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFH43060.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KFH43060.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH43060.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFH43060.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UreE_N PF02814.15 KFH43062.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain ADH_N PF08240.12 KFH43063.1 - 2.7e-28 98.0 0.6 5.5e-28 97.0 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43063.1 - 7.6e-19 68.0 0.2 1.2e-18 67.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43063.1 - 0.0002 22.4 0.0 0.00034 21.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH43063.1 - 0.0022 17.5 0.6 0.0078 15.7 0.5 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFH43063.1 - 0.063 12.6 0.7 0.098 11.9 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CGI-121 PF08617.10 KFH43064.1 - 8.9e-51 172.2 0.0 1e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF4149 PF13664.6 KFH43065.1 - 4e-22 78.5 1.3 4e-22 78.5 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Tim17 PF02466.19 KFH43066.1 - 0.0097 16.3 6.6 0.013 15.9 5.7 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 KFH43067.1 - 9.1e-42 143.2 67.0 5.5e-36 124.2 48.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH43067.1 - 2e-06 26.9 24.5 4.7e-06 25.7 8.7 2.2 2 0 0 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 KFH43067.1 - 0.0075 15.1 0.8 0.0075 15.1 0.8 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter OATP PF03137.20 KFH43067.1 - 0.14 10.4 16.8 0.04 12.2 3.0 3.7 1 1 3 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2_4 PF13894.6 KFH43069.1 - 4.6e-08 33.2 2.1 0.003 18.3 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH43069.1 - 9.3e-07 29.0 3.1 0.0052 17.2 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 KFH43069.1 - 0.047 14.6 0.1 0.089 13.6 0.1 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_6 PF13912.6 KFH43069.1 - 0.071 13.1 2.1 1.1 9.4 0.3 2.7 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFH43069.1 - 0.14 12.0 0.2 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KFH43069.1 - 0.17 12.2 1.6 3.2 8.2 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFH43069.1 - 0.4 11.0 1.9 4.4 7.7 0.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Aminotran_5 PF00266.19 KFH43070.1 - 1.1e-07 31.2 0.0 3.1e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFH43070.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.13 KFH43071.1 - 2.2e-35 122.3 0.0 2.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH43071.1 - 1.3e-14 54.6 0.0 2.9e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFH43071.1 - 0.00011 21.7 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFH43071.1 - 0.0078 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KFH43071.1 - 0.034 14.7 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SDH_C PF18317.1 KFH43071.1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Semialdhyde_dh PF01118.24 KFH43071.1 - 0.094 13.1 0.0 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease PF00324.21 KFH43072.1 - 8.9e-122 407.1 27.8 1.1e-121 406.8 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH43072.1 - 1.8e-33 116.0 32.7 2.1e-33 115.8 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease Cellulase PF00150.18 KFH43073.1 - 6.3e-19 68.5 4.2 8.7e-19 68.0 4.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cas_Cas02710 PF09670.10 KFH43073.1 - 0.062 12.1 0.5 0.093 11.5 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) LMBR1 PF04791.16 KFH43074.1 - 4.2e-19 68.9 3.1 4.2e-19 68.9 3.1 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein Pal1 PF08316.11 KFH43075.1 - 5.1e-07 30.5 0.0 1.2e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein CKS PF01111.19 KFH43076.1 - 4.8e-32 110.0 0.9 6.3e-32 109.6 0.9 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HsbA PF12296.8 KFH43078.1 - 1.8e-26 92.9 7.9 3e-26 92.2 7.9 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Seryl_tRNA_N PF02403.22 KFH43078.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1069 PF06370.11 KFH43078.1 - 0.073 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) MSA-2c PF12238.8 KFH43078.1 - 8.4 6.3 10.1 2.2e+02 1.7 11.3 2.3 1 1 1 2 2 2 0 Merozoite surface antigen 2c TraC PF07820.12 KFH43079.1 - 0.1 12.9 0.5 0.43 10.9 0.5 2.2 1 1 0 1 1 1 0 TraC-like protein TBCC_N PF16752.5 KFH43079.1 - 0.15 12.5 0.1 5.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Pex14_N PF04695.13 KFH43079.1 - 0.95 10.1 8.2 0.78 10.4 1.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Epimerase PF01370.21 KFH43080.1 - 1.3e-15 57.6 0.1 2.4e-15 56.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH43080.1 - 9.4e-14 51.1 0.0 2e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFH43080.1 - 1.6e-11 43.9 0.0 9.5e-08 31.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFH43080.1 - 2.2e-10 40.7 0.1 3.3e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFH43080.1 - 7.4e-09 35.5 0.1 1.6e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFH43080.1 - 7.1e-07 29.0 0.1 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFH43080.1 - 4.6e-05 23.0 0.0 0.00015 21.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KFH43080.1 - 0.00017 20.8 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFH43080.1 - 0.019 14.1 0.1 0.092 11.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KFH43080.1 - 0.038 13.9 1.0 0.81 9.6 1.0 2.5 1 1 0 1 1 1 0 KR domain LETM1 PF07766.13 KFH43081.1 - 7.7e-105 350.1 1.8 7.7e-105 350.1 1.8 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KFH43081.1 - 0.00032 20.4 0.4 0.0082 15.9 0.0 3.2 4 0 0 4 4 4 1 SAP domain Thioredoxin PF00085.20 KFH43082.1 - 4.5e-32 110.1 0.0 6.8e-26 90.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KFH43082.1 - 3.1e-06 27.6 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFH43082.1 - 1.8e-05 24.8 0.0 6.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFH43082.1 - 0.00011 21.6 0.0 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFH43082.1 - 0.029 14.3 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 KFH43082.1 - 0.047 14.0 0.0 6.7 7.1 0.0 3.5 3 1 1 4 4 4 0 Thioredoxin-like QSOX_Trx1 PF18108.1 KFH43082.1 - 0.067 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain CCDC53 PF10152.9 KFH43082.1 - 0.07 13.6 5.1 1.2 9.5 1.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Thioredoxin_7 PF13899.6 KFH43082.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KFH43082.1 - 0.13 12.1 0.0 0.71 9.6 0.0 4.0 4 0 0 4 4 4 0 F plasmid transfer operon protein FMN_bind_2 PF04299.12 KFH43083.1 - 1.6e-56 190.6 0.0 1.9e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain NIF PF03031.18 KFH43084.1 - 1.3e-37 129.0 0.0 1.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase COX6A PF02046.15 KFH43085.1 - 2.9e-48 163.0 3.1 3.5e-48 162.7 3.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RNase_PH PF01138.21 KFH43086.1 - 1e-34 119.9 0.1 2e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pro_dh PF01619.18 KFH43087.1 - 2.2e-70 237.5 0.0 2.8e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Sporozoite_P67 PF05642.11 KFH43087.1 - 4.7 5.2 6.1 7.5 4.5 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_4 PF01565.23 KFH43088.1 - 7.8e-21 74.3 0.1 1.4e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain RSN1_7TM PF02714.15 KFH43090.1 - 3.6e-82 275.8 15.1 7e-82 274.8 15.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFH43090.1 - 3.3e-38 130.9 1.9 4.1e-38 130.6 0.1 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFH43090.1 - 1.2e-25 90.8 0.0 2.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFH43090.1 - 4.3e-23 81.3 0.1 9.9e-23 80.1 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KFH43090.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KFH43091.1 - 9.3e-15 54.4 0.0 2.6e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43091.1 - 0.0017 18.5 1.8 0.0017 18.5 1.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKcGMP_CC PF16808.5 KFH43091.1 - 0.32 10.9 2.4 0.56 10.1 1.0 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ndc1_Nup PF09531.10 KFH43091.1 - 0.9 8.1 24.0 1.6 7.3 24.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 KFH43091.1 - 5.8 5.1 49.2 11 4.1 49.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OPT PF03169.15 KFH43092.1 - 2e-86 291.0 45.3 2.5e-86 290.7 45.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4131 PF13567.6 KFH43092.1 - 2.4 7.8 11.2 0.18 11.5 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_115 PF15979.5 KFH43093.1 - 7.9e-139 462.8 2.0 1.2e-138 462.2 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KFH43093.1 - 2.2e-45 154.6 0.0 4e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain DUF3425 PF11905.8 KFH43094.1 - 1.1e-11 44.8 0.6 3.4e-11 43.2 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) RNA_pol_Rpc4 PF05132.14 KFH43094.1 - 0.055 13.9 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPBP PF02517.16 KFH43095.1 - 5.2e-14 52.4 11.6 5.2e-14 52.4 11.6 2.3 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Sad1_UNC PF07738.13 KFH43096.1 - 5.3e-35 120.3 0.0 8.3e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 KFH43096.1 - 0.0018 18.4 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain DUF1640 PF07798.11 KFH43096.1 - 0.31 11.1 5.8 0.47 10.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SPX PF03105.19 KFH43096.1 - 0.87 9.4 14.4 0.08 12.8 6.2 2.2 2 0 0 2 2 2 0 SPX domain Sec1 PF00995.23 KFH43097.1 - 2.4e-135 453.0 0.0 2.8e-135 452.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CDP-OH_P_transf PF01066.21 KFH43098.1 - 2.3e-14 53.9 0.7 2.3e-14 53.9 0.7 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3535 PF12054.8 KFH43098.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Aa_trans PF01490.18 KFH43099.1 - 3.3e-63 213.8 25.6 4.2e-63 213.5 25.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fcf2 PF08698.11 KFH43100.1 - 3.1e-31 107.6 0.2 5.3e-31 106.9 0.2 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Sec15 PF04091.12 KFH43101.1 - 6.7e-107 357.5 3.6 6.7e-107 357.5 3.6 2.0 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 KFH43101.1 - 0.00073 19.3 4.5 0.001 18.9 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 KFH43101.1 - 0.03 14.7 3.9 6.7 7.1 0.1 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF3510) MutL_C PF08676.11 KFH43101.1 - 0.051 13.4 0.0 0.24 11.1 0.0 2.2 1 0 0 1 1 1 0 MutL C terminal dimerisation domain COG5 PF10392.9 KFH43101.1 - 0.078 13.2 4.4 0.37 11.0 0.8 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KFH43101.1 - 1.9 8.4 8.0 0.28 11.0 0.6 3.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.12 KFH43101.1 - 5.3 7.1 13.1 4.4 7.4 1.5 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Creatinase_N_2 PF16189.5 KFH43102.1 - 1.2e-53 181.6 0.0 1e-52 178.5 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KFH43102.1 - 5.6e-40 137.3 0.1 4.5e-39 134.3 0.1 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KFH43102.1 - 1.8e-20 72.7 0.1 5.5e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KFH43102.1 - 2.3e-19 70.4 0.0 1.2e-15 58.3 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain HEPN_SAV_6107 PF18726.1 KFH43102.1 - 0.019 15.5 0.3 3.8 8.1 0.1 2.5 2 0 0 2 2 2 0 SAV_6107-like HEPN tRNA-synt_1b PF00579.25 KFH43103.1 - 6.1e-73 245.7 0.0 8.3e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Bmt2 PF11968.8 KFH43104.1 - 2e-84 282.9 0.0 2.5e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KFH43104.1 - 0.0012 18.7 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF434 PF04256.12 KFH43104.1 - 0.018 14.7 0.7 0.037 13.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DER1 PF04511.15 KFH43105.1 - 1.1e-50 172.3 6.4 1.2e-50 172.1 6.4 1.0 1 0 0 1 1 1 1 Der1-like family SPC12 PF06645.13 KFH43106.1 - 2e-27 95.1 0.1 2.3e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KFH43106.1 - 0.054 13.8 0.4 0.068 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4440 PF14534.6 KFH43107.1 - 3.1e-10 40.4 0.0 3.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) zf-Tim10_DDP PF02953.15 KFH43108.1 - 1e-20 73.1 5.3 1.2e-20 72.9 5.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AWS PF17907.1 KFH43108.1 - 0.11 12.5 0.6 0.11 12.5 0.6 1.6 2 0 0 2 2 2 0 AWS domain PNRC PF15365.6 KFH43109.1 - 1.2e-08 34.5 5.8 1.2e-08 34.5 5.8 4.0 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif DUF2015 PF09435.10 KFH43110.1 - 3.8e-47 158.8 0.0 4.3e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) ARD PF03079.14 KFH43111.1 - 8.2e-46 156.0 0.1 1e-45 155.8 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFH43111.1 - 3.4e-08 33.1 0.1 5.5e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFH43111.1 - 7.6e-06 25.9 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain SH3_16 PF18348.1 KFH43111.1 - 0.063 13.1 0.6 0.16 11.8 0.3 1.8 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain WD40 PF00400.32 KFH43112.1 - 3e-59 195.6 15.4 7.2e-09 36.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43112.1 - 2.3e-16 59.8 0.0 0.00027 21.2 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KFH43112.1 - 5.9e-16 58.5 8.2 1.1e-15 57.7 8.2 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KFH43112.1 - 7.9e-07 28.7 0.0 0.55 9.5 0.0 5.0 3 2 3 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 KFH43112.1 - 3.2e-06 26.4 0.2 0.98 8.3 0.0 5.0 1 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFH43112.1 - 0.0091 14.7 0.2 1.8 7.1 0.0 3.2 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 KFH43112.1 - 0.035 14.0 0.0 23 5.1 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFH43112.1 - 0.062 11.8 0.3 1.9 7.0 0.1 2.6 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KFH43112.1 - 0.084 12.2 0.0 6.7 5.9 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.9 KFH43112.1 - 0.17 10.5 0.0 1.9 7.0 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.25 KFH43113.1 - 1.8e-55 188.2 0.0 2.8e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43113.1 - 1.3e-34 119.7 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH43113.1 - 2.3e-15 56.7 0.0 7.6e-12 45.1 0.0 2.7 1 1 2 3 3 3 2 Kinase-like Kdo PF06293.14 KFH43113.1 - 0.0046 16.3 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH43113.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UAA PF08449.11 KFH43114.1 - 9.4e-08 31.6 15.7 1.3e-07 31.2 15.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFH43114.1 - 9.7e-05 22.6 6.3 9.7e-05 22.6 6.3 2.4 2 1 0 2 2 2 1 EamA-like transporter family Ldh_1_C PF02866.18 KFH43115.1 - 5e-46 156.7 0.0 7.6e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFH43115.1 - 6.7e-43 146.2 0.1 9.9e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFH43115.1 - 0.002 17.2 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFH43115.1 - 0.0022 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFH43115.1 - 0.038 14.4 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KFH43115.1 - 0.06 12.8 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFH43115.1 - 0.094 12.0 0.0 0.46 9.8 0.0 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMM1 PF10296.9 KFH43116.1 - 5.3e-139 462.9 0.0 1.7e-137 458.0 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 GIDA PF01134.22 KFH43117.1 - 6.1e-155 516.1 0.0 7.7e-155 515.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFH43117.1 - 3.7e-67 226.6 0.0 5.4e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KFH43117.1 - 5.7e-07 29.2 0.1 9.5e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH43117.1 - 1.5e-05 24.3 0.0 3.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH43117.1 - 0.001 18.3 1.6 0.001 18.3 1.6 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFH43117.1 - 0.0041 16.4 0.1 0.0087 15.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFH43117.1 - 0.0075 15.0 1.3 0.1 11.3 0.7 2.3 2 0 0 2 2 2 1 HI0933-like protein Tyr-DNA_phospho PF06087.12 KFH43118.1 - 3.8e-87 292.9 0.0 4.4e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KFH43118.1 - 8.5e-05 22.4 0.0 0.0034 17.3 0.0 2.6 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.20 KFH43118.1 - 0.0018 18.1 0.9 0.0018 18.1 0.9 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif RCDG1 PF15725.5 KFH43119.1 - 0.1 13.1 2.3 0.13 12.7 2.3 1.2 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein CBFD_NFYB_HMF PF00808.23 KFH43120.1 - 2.5e-19 69.3 0.5 3.7e-19 68.8 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFH43120.1 - 6.1e-16 59.0 0.3 1.1e-15 58.2 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFH43120.1 - 0.038 14.3 0.1 0.074 13.4 0.0 1.5 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 KFH43120.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Xpo1 PF08389.12 KFH43122.1 - 3.8e-07 30.3 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 2 Exportin 1-like protein Importin_rep_3 PF18806.1 KFH43122.1 - 0.00026 21.0 0.0 0.013 15.5 0.0 3.3 3 0 0 3 3 3 1 Importin 13 repeat HEAT PF02985.22 KFH43122.1 - 0.12 12.7 1.9 2.4 8.6 0.2 3.9 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L23eN PF03939.13 KFH43123.1 - 5.1e-25 87.4 9.6 5.1e-25 87.4 9.6 2.8 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFH43123.1 - 4.3e-16 59.0 0.3 1.1e-15 57.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_S10 PF00338.22 KFH43124.1 - 8e-26 90.1 0.0 1.3e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-rbx1 PF12678.7 KFH43126.1 - 9.1e-25 86.7 12.5 1.2e-24 86.3 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFH43126.1 - 3.1e-17 62.4 9.8 4e-17 62.1 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFH43126.1 - 2.3e-06 27.8 13.5 8.3e-05 22.8 13.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFH43126.1 - 0.001 18.9 13.8 0.074 12.9 13.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH43126.1 - 0.0015 18.4 11.1 0.025 14.4 11.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH43126.1 - 0.1 12.5 10.0 0.34 10.8 3.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH43126.1 - 0.19 11.8 6.3 0.67 10.0 6.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KFH43126.1 - 0.65 9.8 16.8 53 3.7 16.8 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KFH43126.1 - 0.88 9.8 9.3 5.2 7.3 9.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFH43126.1 - 1.6 8.4 15.1 2.2e+02 1.6 15.1 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Histone PF00125.24 KFH43127.1 - 9.9e-41 139.2 1.0 1.6e-40 138.5 0.6 1.6 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFH43127.1 - 0.00022 21.3 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFH43127.1 - 0.036 14.3 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFH43127.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CorA PF01544.18 KFH43128.1 - 1.2e-43 149.5 0.0 2.7e-43 148.4 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FA_hydroxylase PF04116.13 KFH43129.1 - 1.6e-24 86.7 16.5 1.6e-24 86.7 16.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_8 PF13450.6 KFH43130.1 - 6.9e-15 55.0 0.4 2.9e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH43130.1 - 2e-07 31.0 3.8 3.5e-07 30.1 0.7 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH43130.1 - 1.1e-06 28.0 1.6 1.7e-06 27.4 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH43130.1 - 4e-06 26.3 0.4 1.1e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH43130.1 - 7.3e-06 25.4 0.5 2.2e-05 23.8 0.1 2.0 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.24 KFH43130.1 - 1.5e-05 24.5 0.3 5.2e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KFH43130.1 - 2.2e-05 24.9 0.9 0.00018 22.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH43130.1 - 5.1e-05 22.2 1.7 0.00015 20.6 0.6 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFH43130.1 - 5.1e-05 22.8 0.7 7.7e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFH43130.1 - 0.00017 20.8 0.4 0.3 10.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFH43130.1 - 0.00039 20.5 0.1 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFH43130.1 - 0.0069 15.5 0.2 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFH43130.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH43130.1 - 0.012 14.9 0.4 0.46 9.7 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KFH43130.1 - 0.014 14.3 0.4 0.014 14.3 0.4 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KFH43130.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_S9 PF00326.21 KFH43130.1 - 0.059 12.8 0.1 0.17 11.3 0.1 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family GIDA PF01134.22 KFH43130.1 - 0.094 11.8 1.3 0.19 10.8 1.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn-C2H2_12 PF18112.1 KFH43130.1 - 0.38 11.3 2.1 1 9.9 2.1 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain adh_short PF00106.25 KFH43132.1 - 1.5e-28 99.6 0.0 2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH43132.1 - 1.1e-21 77.5 0.0 1.4e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH43132.1 - 9.2e-07 28.9 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 KR domain TRAPP PF04051.16 KFH43133.1 - 2e-43 147.6 0.0 3.1e-43 147.0 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L28e PF01778.17 KFH43135.1 - 2.4e-36 125.0 0.5 3e-36 124.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_hydro_3_C PF01915.22 KFH43136.1 - 2e-50 171.6 0.1 3.4e-50 170.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH43136.1 - 5.7e-42 144.2 0.0 8.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFH43136.1 - 3.1e-24 84.8 0.0 7.4e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.13 KFH43136.1 - 0.13 12.1 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Pro-kuma_activ PF09286.11 KFH43138.1 - 2.6e-23 82.9 0.1 5.5e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KFH43138.1 - 4.4e-06 26.2 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Subtilase family Med13_N PF11597.8 KFH43138.1 - 0.15 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Antig_Caf1 PF09255.10 KFH43140.1 - 0.052 13.7 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Caf1 Capsule antigen 4HBT_2 PF13279.6 KFH43141.1 - 1.2e-18 67.7 0.0 1.4e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Epsilon_antitox PF08998.11 KFH43141.1 - 0.039 14.2 0.2 0.039 14.2 0.2 1.5 2 0 0 2 2 2 0 Bacterial epsilon antitoxin 4HBT PF03061.22 KFH43141.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily MFS_1 PF07690.16 KFH43142.1 - 2e-23 82.9 26.2 2e-23 82.9 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFH43142.1 - 5.2e-05 22.7 7.4 0.067 12.5 5.3 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 KFH43142.1 - 0.091 12.6 0.0 0.091 12.6 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain PTR2 PF00854.21 KFH43144.1 - 4.8e-75 252.9 7.8 7.1e-75 252.3 7.8 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFH43144.1 - 9.2e-05 21.5 20.9 0.00016 20.7 17.5 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.21 KFH43144.1 - 0.042 13.6 1.6 0.51 10.0 0.5 2.4 2 0 0 2 2 2 0 Cation efflux family DUF4231 PF14015.6 KFH43144.1 - 2.1 8.9 4.8 23 5.5 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) RseC_MucC PF04246.12 KFH43144.1 - 8.8 6.3 9.8 16 5.5 0.1 3.9 2 1 2 4 4 4 0 Positive regulator of sigma(E), RseC/MucC LacAB_rpiB PF02502.18 KFH43145.1 - 3.1e-44 150.3 0.4 3.5e-44 150.2 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Peptidase_M14 PF00246.24 KFH43146.1 - 8.9e-38 130.7 0.0 1.2e-37 130.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Thi4 PF01946.17 KFH43147.1 - 1.6e-114 381.0 0.1 2e-114 380.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFH43147.1 - 5.2e-09 36.1 0.8 3.8e-08 33.3 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH43147.1 - 7.5e-06 26.1 0.3 2e-05 24.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFH43147.1 - 0.00017 20.7 0.3 0.00042 19.5 0.3 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFH43147.1 - 0.00017 21.6 0.3 0.00061 19.8 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFH43147.1 - 0.00084 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH43147.1 - 0.003 16.7 2.2 0.069 12.2 0.4 2.9 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KFH43147.1 - 0.032 12.9 0.2 0.25 10.0 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KFH43147.1 - 0.034 13.5 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFH43147.1 - 0.058 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KFH43147.1 - 0.11 11.7 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH43147.1 - 0.12 12.9 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KFH43148.1 - 1.6e-31 109.7 32.3 1.8e-19 69.9 12.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFH43148.1 - 1.9e-20 73.1 40.4 3.1e-14 52.7 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KFH43148.1 - 2.8 7.6 6.0 2.8 7.6 0.1 3.0 2 1 1 3 3 3 0 Cyclin M transmembrane N-terminal domain V-SNARE_C PF12352.8 KFH43149.1 - 6.6e-14 51.9 0.5 1.6e-13 50.7 0.5 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFH43149.1 - 6e-06 26.1 0.4 3.1e-05 23.8 0.0 2.2 3 0 0 3 3 3 1 Sec20 TPR_MLP1_2 PF07926.12 KFH43149.1 - 0.00076 19.5 5.7 0.012 15.7 1.0 2.4 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF1804 PF08822.11 KFH43149.1 - 0.013 15.5 0.6 0.067 13.2 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1804) Sigma70_r4 PF04545.16 KFH43149.1 - 0.099 12.2 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4407 PF14362.6 KFH43149.1 - 0.82 9.0 7.0 1.2 8.4 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KFH43149.1 - 0.94 9.3 4.6 1.6 8.6 0.3 3.1 3 1 0 3 3 3 0 Septum formation initiator PspB PF06667.12 KFH43149.1 - 1.6 8.9 3.9 3.9 7.6 3.9 1.7 1 0 0 1 1 1 0 Phage shock protein B T2SSM PF04612.12 KFH43149.1 - 6.6 6.8 10.4 22 5.0 0.2 3.9 2 1 2 4 4 4 0 Type II secretion system (T2SS), protein M VIT1 PF01988.19 KFH43150.1 - 2.8e-38 132.0 0.1 3.6e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 VIT family CHCH PF06747.13 KFH43151.1 - 7.2e-06 26.0 5.0 1.2e-05 25.3 5.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KFH43151.1 - 5.9 7.4 7.6 0.27 11.7 2.0 1.7 2 0 0 2 2 2 0 GCK domain zf-C2HC5 PF06221.13 KFH43152.1 - 4.6e-21 74.6 6.3 7.2e-21 73.9 6.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type NAM-associated PF14303.6 KFH43152.1 - 0.02 15.6 0.0 0.34 11.6 0.0 2.5 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Rtf2 PF04641.12 KFH43152.1 - 0.021 14.2 0.6 0.042 13.2 0.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3435 PF11917.8 KFH43152.1 - 0.15 10.9 3.0 0.23 10.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_hydro_45 PF02015.16 KFH43153.1 - 7e-81 271.1 14.1 8.5e-81 270.9 14.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 AhpC-TSA_2 PF13911.6 KFH43154.1 - 1.2e-18 67.3 0.0 2.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans PF04082.18 KFH43154.1 - 3.2e-12 46.0 0.0 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Whi5 PF08528.11 KFH43155.1 - 2.7e-12 46.0 0.0 4.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Aminotran_5 PF00266.19 KFH43156.1 - 1.7e-19 70.1 0.0 2.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Ldh_1_C PF02866.18 KFH43157.1 - 1.1e-47 162.0 0.0 1.8e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFH43157.1 - 6.8e-42 142.9 0.0 2.3e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFH43157.1 - 0.00016 20.8 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFH43157.1 - 0.012 16.0 0.2 0.055 13.9 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.21 KFH43158.1 - 3.1e-15 56.1 0.3 4.4e-15 55.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KFH43158.1 - 0.00012 20.6 1.2 0.12 10.7 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NAD_binding_10 PF13460.6 KFH43159.1 - 4.8e-12 46.1 0.2 8.3e-12 45.4 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFH43159.1 - 5.9e-12 45.6 0.0 7.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KFH43159.1 - 0.051 13.8 0.2 0.096 13.0 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 KFH43160.1 - 7.1e-12 44.9 0.6 1.2e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43160.1 - 4.6e-09 36.2 9.6 7.5e-09 35.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_3 PF12776.7 KFH43162.1 - 6.9e-24 84.7 0.1 1.6e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Str_synth PF03088.16 KFH43163.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Strictosidine synthase p450 PF00067.22 KFH43164.1 - 2.4e-53 181.6 0.0 3.2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 IL32 PF15225.6 KFH43164.1 - 0.066 13.6 0.3 0.26 11.7 0.1 2.1 2 0 0 2 2 2 0 Interleukin 32 MotA_ExbB PF01618.16 KFH43164.1 - 0.38 10.5 2.5 0.38 10.5 0.8 1.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Dak1 PF02733.17 KFH43165.1 - 4.6e-98 327.9 0.0 6.4e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KFH43165.1 - 2.9e-41 141.3 2.5 2.9e-41 141.3 2.5 1.7 2 0 0 2 2 2 1 DAK2 domain E1-E2_ATPase PF00122.20 KFH43166.1 - 1.3e-17 63.9 0.0 3e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFH43166.1 - 1.2e-15 58.3 2.0 1.5e-09 38.5 2.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFH43166.1 - 0.0023 17.7 0.1 0.039 13.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH43166.1 - 0.019 15.0 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Cation transport ATPase (P-type) DUF4059 PF13268.6 KFH43166.1 - 0.48 10.9 4.4 51 4.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) F-box-like PF12937.7 KFH43167.1 - 8.4e-08 32.0 0.3 2.3e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like TIM PF00121.18 KFH43168.1 - 3.7e-51 173.9 0.0 4.2e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Pox_EPC_I2-L1 PF12575.8 KFH43168.1 - 0.044 14.0 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 TPK_catalytic PF04263.16 KFH43169.1 - 6.7e-29 100.4 0.0 9.7e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KFH43169.1 - 5.1e-23 80.6 0.1 7.6e-23 80.0 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Malate_synthase PF01274.22 KFH43170.1 - 2e-216 719.3 0.0 2.3e-216 719.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KFH43170.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HIG_1_N PF04588.13 KFH43171.1 - 0.00028 21.1 0.9 0.00028 21.1 0.9 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF5353 PF17304.2 KFH43172.1 - 1.4e-14 53.5 5.3 2.3e-14 52.9 5.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Adaptin_N PF01602.20 KFH43173.1 - 2.3e-118 396.0 8.9 2.9e-118 395.7 8.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFH43173.1 - 1.1e-51 175.1 7.1 3.3e-51 173.5 0.1 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFH43173.1 - 4.1e-14 52.7 8.7 9.5e-08 32.3 0.5 4.6 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KFH43173.1 - 2.1e-10 39.9 4.7 0.0053 16.9 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFH43173.1 - 1.3e-06 28.8 5.4 0.89 10.1 0.2 6.3 6 0 0 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.9 KFH43173.1 - 0.013 15.5 0.2 34 4.5 0.0 4.3 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KFH43173.1 - 0.021 14.4 1.6 3.9 7.0 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 KFH43173.1 - 0.12 12.5 2.0 3.8 7.7 0.1 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KFH43173.1 - 0.21 11.7 4.9 6.9 6.9 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Collagen_mid PF15984.5 KFH43174.1 - 9.6e-05 22.2 15.6 0.0086 15.8 3.6 2.0 1 1 1 2 2 2 2 Bacterial collagen, middle region Senescence PF06911.12 KFH43174.1 - 0.0012 19.2 1.1 0.0017 18.7 1.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein Rad60-SLD_2 PF13881.6 KFH43175.1 - 6.9e-12 45.5 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFH43175.1 - 4.4e-05 23.2 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFH43175.1 - 0.00061 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HET PF06985.11 KFH43176.1 - 1.2e-34 119.7 0.0 2.1e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC_tran PF00005.27 KFH43177.1 - 2.2e-22 80.1 0.0 3.5e-10 40.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFH43177.1 - 4.1e-08 33.4 0.3 0.015 15.2 0.2 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFH43177.1 - 4e-06 27.0 0.0 0.0032 17.7 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFH43177.1 - 2.9e-05 24.7 0.1 0.059 13.9 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFH43177.1 - 0.0002 21.1 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH43177.1 - 0.0016 18.8 0.6 2.1 8.7 0.1 2.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KFH43177.1 - 0.011 15.9 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFH43177.1 - 0.014 15.9 0.0 8.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFH43177.1 - 0.014 15.1 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFH43177.1 - 0.015 15.6 0.1 5.3 7.3 0.0 2.9 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 KFH43177.1 - 0.03 14.7 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KFH43177.1 - 0.036 14.5 0.1 0.99 9.8 0.0 3.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase1 PF18748.1 KFH43177.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 TniB PF05621.11 KFH43177.1 - 0.1 12.0 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 KFH43177.1 - 0.13 12.0 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KFH43177.1 - 0.21 11.6 0.0 25 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.6 KFH43178.1 - 0.0002 21.3 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFH43178.1 - 0.00038 19.7 0.0 0.00047 19.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KFH43178.1 - 0.016 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFH43178.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KFH43178.1 - 0.038 14.7 0.0 0.096 13.4 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KFH43178.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mlh1_C PF16413.5 KFH43180.1 - 3.3e-93 312.0 0.0 5.3e-93 311.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFH43180.1 - 4.2e-34 116.8 0.0 7.8e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFH43180.1 - 2.7e-12 46.7 0.0 5.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFH43180.1 - 2.6e-06 27.9 0.0 6.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GHMP_kinases_N PF00288.26 KFH43181.1 - 3.7e-15 55.9 3.9 3.7e-15 55.9 3.9 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFH43181.1 - 2.1e-08 34.4 0.0 5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Sugar_tr PF00083.24 KFH43183.1 - 4.6e-78 263.1 19.9 5.3e-78 262.9 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH43183.1 - 5.1e-27 94.7 26.5 6.6e-24 84.5 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH43183.1 - 1.2e-06 27.3 11.5 2.7e-06 26.2 0.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 KFH43183.1 - 0.0018 17.4 1.7 0.0059 15.7 1.7 1.9 1 1 0 1 1 1 1 PUCC protein Syntaxin-18_N PF10496.9 KFH43184.1 - 8.9e-10 38.7 0.2 6.3e-08 32.8 0.0 2.9 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KFH43184.1 - 0.0022 18.0 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 KFH43184.1 - 0.0062 16.3 0.3 0.086 12.6 0.1 2.4 2 0 0 2 2 2 1 Synaptobrevin BLOC1_2 PF10046.9 KFH43184.1 - 0.79 10.1 8.1 1 9.7 6.5 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HisG PF01634.18 KFH43185.1 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 ATP phosphoribosyltransferase AAA_16 PF13191.6 KFH43185.1 - 0.0015 18.9 0.1 0.028 14.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KFH43185.1 - 0.06 13.9 0.7 20 5.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain ketoacyl-synt PF00109.26 KFH43187.1 - 8.9e-63 212.2 0.0 1.9e-62 211.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFH43187.1 - 1.1e-61 208.7 0.0 1.8e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH43187.1 - 1.4e-55 189.1 0.0 2.1e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH43187.1 - 1.4e-53 181.5 0.1 4e-53 180.0 0.1 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFH43187.1 - 6.3e-32 110.1 0.1 1.6e-31 108.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH43187.1 - 3e-21 76.0 0.0 1.6e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH43187.1 - 1.5e-20 73.7 0.2 5.4e-15 55.8 0.3 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KFH43187.1 - 1.3e-15 58.7 0.0 1e-14 55.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH43187.1 - 2e-11 43.9 0.6 1.3e-10 41.3 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KFH43187.1 - 2.2e-11 44.3 0.0 2.7e-10 40.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH43187.1 - 1.1e-10 42.0 0.0 7e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH43187.1 - 1.5e-09 37.8 0.0 7.5e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH43187.1 - 2.3e-07 30.8 0.0 5.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH43187.1 - 1.1e-06 28.3 0.3 5.8e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KFH43187.1 - 3.3e-06 26.6 0.0 7.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KFH43187.1 - 1.4e-05 25.3 0.1 5.1e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KFH43187.1 - 3.6e-05 23.6 0.1 9.3e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KFH43187.1 - 0.0053 16.2 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KFH43187.1 - 0.007 15.9 0.0 0.033 13.7 0.0 2.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 KFH43187.1 - 0.0086 15.9 0.3 0.025 14.4 0.3 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCMT PF01135.19 KFH43187.1 - 0.037 13.8 0.1 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SAT PF16073.5 KFH43187.1 - 0.047 13.4 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Crystall_2 PF09076.10 KFH43188.1 - 0.00036 20.4 0.3 0.00067 19.5 0.3 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin GFO_IDH_MocA PF01408.22 KFH43189.1 - 1.2e-11 45.5 0.0 2.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KFH43189.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.17 KFH43189.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF1077 PF06417.12 KFH43190.1 - 4.3e-50 168.6 5.0 5.2e-50 168.4 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DEAD PF00270.29 KFH43191.1 - 1.1e-44 152.2 0.0 2.4e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH43191.1 - 3.9e-19 69.0 0.0 2e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFH43191.1 - 3.1e-16 59.4 0.0 6.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFH43191.1 - 0.002 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP_sub_h PF10775.9 KFH43191.1 - 0.11 12.5 0.9 1.4 9.0 0.3 2.6 2 0 0 2 2 2 0 ATP synthase complex subunit h ERCC3_RAD25_C PF16203.5 KFH43191.1 - 0.12 11.5 0.0 0.42 9.8 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFH43193.1 - 3.3e-44 150.7 0.1 3.4e-42 144.2 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH43193.1 - 1.9e-24 86.2 0.1 1e-20 74.1 0.0 3.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH43193.1 - 2.1e-08 34.3 0.1 4.8e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KFH43193.1 - 0.037 13.9 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KFH43193.1 - 0.086 13.1 0.8 2 8.7 1.3 2.9 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFH43193.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.11 KFH43194.1 - 5.6e-44 149.1 0.0 6.5e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Aa_trans PF01490.18 KFH43195.1 - 4.3e-31 108.0 27.3 5e-31 107.8 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KFH43195.1 - 4.1e-06 25.9 34.2 2.9e-05 23.1 23.2 2.9 1 1 1 2 2 2 2 Amino acid permease SLATT_1 PF18181.1 KFH43195.1 - 0.34 10.8 2.6 7.7 6.5 0.8 3.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Med25_SD1 PF11235.8 KFH43196.1 - 0.011 16.0 0.2 0.024 15.0 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Astro_capsid_p PF12226.8 KFH43196.1 - 0.017 14.3 8.5 0.026 13.7 8.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 KFH43196.1 - 0.028 13.8 1.9 0.039 13.3 1.9 1.3 1 0 0 1 1 1 0 BUD22 HEAT PF02985.22 KFH43196.1 - 0.048 13.9 1.5 2.3 8.7 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat CNDH2_C PF16858.5 KFH43196.1 - 0.23 11.3 1.5 16 5.3 1.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 KFH43196.1 - 1.2 7.3 7.4 1.9 6.6 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KFH43196.1 - 3.9 5.4 14.6 1.4 7.0 11.4 1.8 2 0 0 2 2 2 0 DNA polymerase phi Prothymosin PF03247.14 KFH43196.1 - 8.3 6.9 20.4 17 6.0 20.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF202 PF02656.15 KFH43197.1 - 2.4e-14 53.5 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Aminotran_1_2 PF00155.21 KFH43199.1 - 3.2e-89 299.6 0.1 4.9e-89 299.0 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.16 KFH43200.1 - 7e-53 179.8 23.0 1e-52 179.2 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43200.1 - 5.2e-09 35.5 9.4 5.2e-09 35.5 9.4 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFH43200.1 - 0.0023 16.3 2.7 0.006 14.9 2.7 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane PF01061.24 KFH43201.1 - 2.2e-84 282.1 47.4 1.8e-46 158.2 14.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFH43201.1 - 1.8e-39 135.4 0.0 6.4e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFH43201.1 - 7.3e-24 83.5 9.0 1e-23 83.0 0.2 3.2 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KFH43201.1 - 1.4e-15 57.3 22.0 4.1e-10 39.3 3.9 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KFH43201.1 - 2.9e-05 24.5 0.1 0.0063 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFH43201.1 - 7.1e-05 22.8 0.2 0.0082 16.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 KFH43201.1 - 0.00016 22.2 0.0 0.0004 20.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KFH43201.1 - 0.0016 18.1 0.6 0.0064 16.1 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH43201.1 - 0.0024 18.1 0.4 0.66 10.2 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFH43201.1 - 0.0044 16.9 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH43201.1 - 0.01 15.6 0.3 0.086 12.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFH43201.1 - 0.015 15.6 2.0 1.1 9.5 0.8 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFH43201.1 - 0.034 14.7 0.0 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFH43201.1 - 0.05 13.4 0.8 8 6.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KFH43201.1 - 0.15 11.8 0.6 5.6 6.6 0.4 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFH43201.1 - 0.22 11.1 1.7 2.1 7.9 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KFH43201.1 - 0.24 11.5 0.3 22 5.1 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase HsbA PF12296.8 KFH43202.1 - 1.9e-08 34.7 0.0 2.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Sec8_exocyst PF04048.14 KFH43202.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HD PF01966.22 KFH43203.1 - 2.8e-05 24.3 0.5 5.6e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 HD domain GMP_synt_C PF00958.22 KFH43204.1 - 0.0047 17.0 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 GMP synthase C terminal domain SMN PF06003.12 KFH43204.1 - 0.083 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) L31 PF09784.9 KFH43205.1 - 8.1e-45 151.4 0.6 9.1e-45 151.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.21 KFH43205.1 - 0.049 14.4 0.6 0.06 14.2 0.6 1.1 1 0 0 1 1 1 0 H-NS histone family EthD PF07110.11 KFH43206.1 - 6.1e-21 75.4 0.6 7.6e-21 75.1 0.6 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFH43206.1 - 4e-05 24.0 0.1 6.1e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Ras PF00071.22 KFH43207.1 - 5.4e-58 195.2 0.0 7.2e-58 194.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH43207.1 - 3.5e-34 117.6 0.0 5.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH43207.1 - 9.5e-14 51.2 0.0 1.7e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH43207.1 - 2.6e-05 23.9 0.0 3.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFH43207.1 - 7.8e-05 22.7 0.0 0.00021 21.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFH43207.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFH43207.1 - 0.00048 20.5 0.1 0.00072 20.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFH43207.1 - 0.057 13.3 0.1 1.8 8.4 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KFH43207.1 - 0.14 12.5 0.0 0.85 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KFH43207.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PI3_PI4_kinase PF00454.27 KFH43208.1 - 2.1e-49 168.6 0.0 5.3e-49 167.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KFH43208.1 - 9.9e-49 165.3 6.5 1e-48 165.3 0.1 3.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.23 KFH43208.1 - 4.5e-10 39.3 7.0 9.4e-10 38.2 7.0 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KFH43208.1 - 2e-09 37.1 1.0 6e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 FATC domain CBFD_NFYB_HMF PF00808.23 KFH43209.1 - 3.8e-13 49.5 1.8 6.1e-13 48.8 1.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFH43209.1 - 0.013 15.8 0.1 0.013 15.8 0.1 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KFH43209.1 - 0.033 14.3 1.5 0.065 13.3 1.5 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PsbQ PF05757.11 KFH43209.1 - 0.33 10.6 2.8 0.69 9.6 2.8 1.5 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-C3HC4_3 PF13920.6 KFH43210.1 - 4.2e-10 39.3 7.0 6.1e-10 38.8 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH43210.1 - 1.8e-06 27.7 7.0 3.2e-06 26.9 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFH43210.1 - 2.6e-06 27.7 8.2 4.1e-06 27.0 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFH43210.1 - 2.7e-06 27.1 9.3 4.3e-06 26.5 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH43210.1 - 2.8e-06 27.0 10.4 4.7e-06 26.4 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFH43210.1 - 5.3e-05 23.2 3.7 9.1e-05 22.4 3.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFH43210.1 - 6.6e-05 22.8 8.9 0.00011 22.1 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH43210.1 - 7.3e-05 22.7 5.0 0.00015 21.7 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFH43210.1 - 0.027 14.8 5.3 0.057 13.7 5.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFH43210.1 - 0.029 14.1 6.0 0.054 13.3 6.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFH43210.1 - 0.086 13.0 8.5 0.17 12.1 8.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFH43210.1 - 1.7 8.5 4.9 3.3 7.5 4.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KFH43210.1 - 9.3 6.5 8.1 5.7e+02 0.8 8.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DNApol_Exo PF18136.1 KFH43211.1 - 1.2e-104 349.4 0.0 2.1e-104 348.6 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFH43211.1 - 7.8e-57 193.0 0.0 1.3e-56 192.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 KFH43211.1 - 0.1 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) DNA_pol_A_exo1 PF01612.20 KFH43211.1 - 0.26 11.0 2.9 4.1 7.1 1.0 3.3 2 1 0 2 2 2 0 3'-5' exonuclease TMEM208_SND2 PF05620.11 KFH43212.1 - 1.2e-50 171.6 0.0 1.3e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Myb_DNA-bind_6 PF13921.6 KFH43213.1 - 4.9e-15 55.5 0.3 1.4e-14 54.1 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KFH43213.1 - 1.2e-13 51.1 0.6 1.2e-13 51.1 0.6 3.8 4 0 0 4 4 4 2 HSA Myb_DNA-binding PF00249.31 KFH43213.1 - 0.016 15.4 0.1 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-T_C PF15511.6 KFH43214.1 - 7.5e-09 35.7 0.1 9.5e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFH43214.1 - 2e-05 25.0 0.1 2.5e-05 24.6 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFH43214.1 - 7.4e-05 22.8 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KFH43214.1 - 0.00016 21.8 0.1 0.00038 20.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFH43214.1 - 0.00037 20.8 0.1 0.00052 20.3 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KFH43214.1 - 0.0084 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit UPF0137 PF03677.13 KFH43214.1 - 0.024 14.5 0.2 0.029 14.2 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Bromo_TP PF07524.13 KFH43214.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 KFH43214.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Glyco_transf_28 PF03033.20 KFH43215.1 - 1.9e-16 60.4 0.0 1e-15 58.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFH43215.1 - 2.5e-06 26.6 0.0 4.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KFH43215.1 - 0.011 16.0 0.0 0.062 13.7 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain FAD_binding_4 PF01565.23 KFH43217.1 - 4.2e-11 42.7 4.3 2.6e-05 24.0 2.0 2.7 2 1 1 3 3 3 2 FAD binding domain Arf PF00025.21 KFH43218.1 - 1.6e-39 135.2 0.0 2.1e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFH43218.1 - 5.5e-12 45.5 0.0 7.3e-07 28.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFH43218.1 - 5.2e-09 35.9 0.0 1.4e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFH43218.1 - 2.2e-08 34.3 0.0 4.1e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFH43218.1 - 7.3e-08 32.0 0.0 8.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFH43218.1 - 3.6e-07 29.8 0.0 6.2e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFH43218.1 - 0.00066 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH43218.1 - 0.00068 19.2 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFH43218.1 - 0.077 12.0 0.0 0.17 10.9 0.1 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF5321 PF17254.2 KFH43219.1 - 6.3e-54 181.7 4.3 2.7e-50 169.9 0.4 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5321) RAMP4 PF06624.12 KFH43219.1 - 0.47 10.6 2.3 0.66 10.1 0.0 2.3 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF2353 PF09789.9 KFH43220.1 - 0.003 17.0 6.3 0.0048 16.3 6.3 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Aurora-A_bind PF09041.10 KFH43220.1 - 0.24 11.5 1.5 21 5.3 0.1 2.5 2 0 0 2 2 2 0 Aurora-A binding YscO-like PF16789.5 KFH43220.1 - 1.2 9.2 9.8 0.87 9.6 7.7 1.7 1 1 0 1 1 1 0 YscO-like protein YabA PF06156.13 KFH43220.1 - 2.9 8.6 5.9 3.6 8.3 1.0 2.7 3 0 0 3 3 3 0 Initiation control protein YabA Cwf_Cwc_15 PF04889.12 KFH43221.1 - 4e-82 275.7 16.9 4.6e-82 275.5 16.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KFH43221.1 - 0.02 15.0 18.9 0.027 14.6 18.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KFH43221.1 - 0.58 8.4 16.1 0.64 8.2 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFH43221.1 - 6.4 4.8 22.6 7.3 4.7 22.6 1.1 1 0 0 1 1 1 0 Nop14-like family EBP PF05241.12 KFH43222.1 - 3.2e-55 186.3 8.8 4.2e-55 186.0 8.8 1.1 1 0 0 1 1 1 1 Emopamil binding protein Sedlin_N PF04628.13 KFH43223.1 - 3.8e-43 146.7 0.0 5e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFH43223.1 - 0.005 16.8 0.2 0.13 12.2 0.1 2.1 1 1 1 2 2 2 1 Sybindin-like family Kri1 PF05178.12 KFH43224.1 - 1.9e-29 102.3 21.9 1.9e-29 102.3 21.9 6.2 5 2 1 6 6 6 1 KRI1-like family Kri1_C PF12936.7 KFH43224.1 - 3.5e-27 94.4 0.0 3.5e-27 94.4 0.0 4.8 5 1 1 6 6 6 1 KRI1-like family C-terminal TraG-D_C PF12696.7 KFH43224.1 - 0.17 11.9 2.6 5.4 7.0 0.0 3.0 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Cullin PF00888.22 KFH43225.1 - 7.4e-167 556.7 0.0 9e-167 556.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFH43225.1 - 3.3e-18 65.5 2.7 2.9e-15 56.1 0.1 3.3 3 0 0 3 3 3 2 Cullin protein neddylation domain Cation_efflux PF01545.21 KFH43226.1 - 9.9e-48 162.5 7.9 1.4e-47 162.0 7.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFH43226.1 - 0.0006 19.9 1.7 0.00064 19.8 0.1 1.8 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Nup192 PF11894.8 KFH43227.1 - 0 1479.1 0.0 0 1478.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Kinetochor_Ybp2 PF08568.10 KFH43228.1 - 7.9e-93 312.1 0.0 8.7e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-C3HC4_3 PF13920.6 KFH43229.1 - 0.0006 19.6 11.6 0.00092 19.0 11.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFH43229.1 - 0.081 12.8 6.7 0.13 12.1 6.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFH43229.1 - 6.4 6.8 12.7 10 6.2 12.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PI3_PI4_kinase PF00454.27 KFH43231.1 - 6.8e-35 121.1 0.0 2.3e-34 119.3 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KFH43231.1 - 3.3e-20 71.8 0.0 6.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KFH43231.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 KFH43231.1 - 0.096 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal PI3Ka PF00613.20 KFH43231.1 - 0.25 10.7 0.4 0.46 9.9 0.4 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Na_H_Exchanger PF00999.21 KFH43232.1 - 8.4e-72 242.1 41.2 1e-71 241.7 41.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PDR_CDR PF06422.12 KFH43232.1 - 8.9 6.3 6.5 1.8 8.5 0.4 2.8 2 0 0 2 2 2 0 CDR ABC transporter Abhydrolase_3 PF07859.13 KFH43233.1 - 1.4e-19 70.8 0.0 2.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH43233.1 - 4.4e-13 48.8 0.0 1.5e-05 24.0 0.1 2.7 2 1 0 2 2 2 2 Steryl acetyl hydrolase G-patch_2 PF12656.7 KFH43234.1 - 3.3e-20 71.9 0.7 3.3e-20 71.9 0.7 2.6 2 1 0 2 2 2 1 G-patch domain G-patch PF01585.23 KFH43234.1 - 0.16 11.9 2.1 1.2 9.1 2.1 2.5 1 1 0 1 1 1 0 G-patch domain TPR_1 PF00515.28 KFH43235.1 - 7.9e-35 117.3 15.1 2.2e-06 27.3 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFH43235.1 - 5.9e-29 97.8 29.2 2.6e-05 24.0 0.0 9.6 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH43235.1 - 3.7e-25 88.0 13.8 5.7e-19 68.1 0.1 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFH43235.1 - 5.3e-20 69.9 7.4 0.011 15.9 0.1 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43235.1 - 5.1e-18 63.7 3.0 0.032 14.2 0.0 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFH43235.1 - 1.1e-17 63.4 14.6 5.6e-07 29.1 2.8 7.3 7 2 1 8 8 7 3 TPR repeat TPR_12 PF13424.6 KFH43235.1 - 3e-17 62.7 17.3 0.014 15.6 0.1 8.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFH43235.1 - 1e-16 61.2 25.9 7.4e-08 32.9 2.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43235.1 - 3.2e-16 58.6 25.6 0.035 14.9 0.1 10.4 4 1 7 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFH43235.1 - 8.6e-13 48.6 21.4 0.013 15.9 0.4 7.2 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFH43235.1 - 3.4e-12 45.8 9.5 1.3 9.6 0.0 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH43235.1 - 9.1e-08 32.3 15.2 0.57 10.9 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFH43235.1 - 6e-06 25.7 9.3 0.23 10.6 2.9 4.8 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFH43235.1 - 0.00036 20.6 11.8 0.37 11.0 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Sel1 PF08238.12 KFH43235.1 - 0.0017 19.0 1.7 4.9 8.0 0.0 5.3 4 0 0 4 4 4 1 Sel1 repeat TPR_20 PF14561.6 KFH43235.1 - 0.03 14.7 7.7 0.14 12.5 0.6 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KFH43235.1 - 0.12 12.0 1.1 12 5.6 1.3 3.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 KFH43235.1 - 0.3 11.0 7.1 36 4.4 0.8 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat PrpF PF04303.13 KFH43236.1 - 1e-85 288.0 0.0 1.2e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 PrpF protein RNase_PH PF01138.21 KFH43237.1 - 7.2e-18 65.4 0.0 1.1e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFH43237.1 - 1.4e-08 34.6 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Fungal_trans PF04082.18 KFH43238.1 - 7.3e-29 100.6 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43238.1 - 2e-09 37.4 10.9 3.3e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.9 KFH43239.1 - 1.6e-101 339.5 1.0 1.6e-101 339.5 1.0 2.7 3 1 0 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_C50 PF03568.17 KFH43240.1 - 4.1e-158 526.6 0.0 3.1e-157 523.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KFH43240.1 - 0.00011 22.4 11.5 0.48 10.8 0.2 6.4 4 2 2 6 6 6 3 Tetratricopeptide repeat CHAT PF12770.7 KFH43240.1 - 0.00062 19.3 0.0 0.03 13.7 0.0 2.6 1 1 1 2 2 2 1 CHAT domain TPR_8 PF13181.6 KFH43240.1 - 0.031 14.5 14.1 0.86 10.0 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFH43240.1 - 0.037 14.1 11.1 41 4.6 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43240.1 - 2.1 8.6 6.9 5.9 7.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFH43241.1 - 6.6e-16 57.9 0.0 9.5e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIR2 PF02146.17 KFH43242.1 - 2.4e-31 109.0 0.0 3.8e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family FGGY_C PF02782.16 KFH43244.1 - 5.1e-22 78.6 0.0 2.2e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFH43244.1 - 9.3e-20 71.2 0.0 1.5e-17 64.0 0.0 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_transf_41 PF13844.6 KFH43246.1 - 1.7e-99 333.4 0.0 1.8e-50 171.8 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KFH43246.1 - 1.1e-21 75.6 0.0 0.00022 20.9 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFH43246.1 - 6.8e-19 66.4 0.2 0.013 15.6 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFH43246.1 - 2.5e-14 52.2 0.0 0.0041 17.2 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH43246.1 - 3.3e-12 45.9 0.4 0.0022 17.6 0.0 6.0 4 1 2 6 6 6 2 TPR repeat TPR_10 PF13374.6 KFH43246.1 - 8.4e-12 44.6 1.5 0.013 15.3 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH43246.1 - 3.2e-10 40.5 4.2 0.045 14.4 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFH43246.1 - 3.5e-10 39.5 0.0 0.021 15.2 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFH43246.1 - 7.6e-10 38.9 8.8 0.022 15.1 0.2 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43246.1 - 8.7e-10 38.6 3.8 0.17 12.8 0.4 5.6 4 2 2 6 6 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43246.1 - 7.5e-07 28.7 0.2 0.12 12.5 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH43246.1 - 7.9e-05 23.1 1.4 1.5 9.4 0.1 4.1 3 1 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.17 KFH43246.1 - 0.0061 17.0 0.2 0.34 11.3 0.0 2.8 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KFH43246.1 - 0.0084 15.3 0.0 1.5 8.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFH43246.1 - 0.014 16.0 0.7 52 4.8 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH43246.1 - 0.023 14.9 0.1 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFH43246.1 - 0.17 12.0 3.0 2.2 8.5 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat NAD_binding_6 PF08030.12 KFH43247.1 - 4.6e-06 26.8 0.0 0.0011 19.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KFH43247.1 - 3.3e-05 24.5 0.0 0.00022 21.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sec23_trunk PF04811.15 KFH43248.1 - 3.4e-79 265.8 0.0 4.7e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFH43248.1 - 1.9e-30 105.4 0.4 4.2e-30 104.3 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFH43248.1 - 1.6e-25 88.9 0.1 4.8e-25 87.4 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFH43248.1 - 1.5e-15 57.0 6.4 2.7e-15 56.1 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFH43248.1 - 1.2e-13 50.8 0.0 3.2e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFH43248.1 - 0.045 13.2 0.4 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 KFH43249.1 - 1.1e-19 70.4 15.7 0.00044 21.0 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43249.1 - 1.3e-14 54.3 6.6 1.4e-05 25.3 0.5 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH43249.1 - 1.5e-07 31.5 0.1 0.00099 19.0 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFH43249.1 - 0.14 11.1 0.1 1.5 7.7 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cation_efflux PF01545.21 KFH43251.1 - 2.2e-13 50.4 11.8 2.8e-13 50.1 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFH43251.1 - 4.7e-09 36.3 0.1 4.7e-09 36.3 0.1 2.0 3 0 0 3 3 3 1 Dimerisation domain of Zinc Transporter DUF4212 PF13937.6 KFH43251.1 - 6.3 7.3 6.2 2 8.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) NCBP3 PF10309.9 KFH43252.1 - 5.3e-21 74.2 0.0 8.5e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DNA_pol_B_palm PF14792.6 KFH43254.1 - 6.9e-22 77.8 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KFH43254.1 - 3.6e-21 75.1 0.3 7.9e-21 74.0 0.3 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFH43254.1 - 6.3e-21 73.9 0.9 1.6e-20 72.7 0.9 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFH43254.1 - 1.4e-11 44.6 0.0 3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFH43254.1 - 5.3e-05 23.7 0.0 0.006 17.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFH43254.1 - 0.025 14.9 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2838 PF10998.8 KFH43255.1 - 7.4e-45 151.7 9.6 7.4e-45 151.7 9.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) ApoLp-III PF07464.11 KFH43255.1 - 0.15 12.2 0.8 0.3 11.2 0.8 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Val_tRNA-synt_C PF10458.9 KFH43255.1 - 0.62 10.4 2.7 19 5.6 1.2 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Apolipoprotein PF01442.18 KFH43255.1 - 1 9.2 6.3 0.52 10.2 3.7 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tropomyosin_1 PF12718.7 KFH43255.1 - 4.4 7.4 6.9 0.22 11.7 1.5 1.5 2 0 0 2 2 2 0 Tropomyosin like DHR10 PF18595.1 KFH43255.1 - 5.7 7.0 7.5 90 3.2 7.5 2.2 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain COX7a PF02238.15 KFH43256.1 - 1.1e-20 73.8 3.9 1.4e-20 73.4 3.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Eco57I PF07669.11 KFH43256.1 - 0.05 14.1 0.1 0.059 13.9 0.1 1.2 1 0 0 1 1 1 0 Eco57I restriction-modification methylase CENP-B_dimeris PF09026.10 KFH43257.1 - 0.028 14.8 2.5 0.031 14.7 2.5 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adaptin_N PF01602.20 KFH43258.1 - 3.7e-142 474.6 4.9 4.3e-142 474.3 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFH43258.1 - 3.5e-15 56.3 0.2 3.5e-15 56.3 0.2 2.3 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFH43258.1 - 3.4e-08 33.7 9.0 0.00024 21.2 0.0 4.7 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFH43258.1 - 1.9e-06 28.2 2.3 0.029 14.8 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats DUF3730 PF12530.8 KFH43258.1 - 7.4e-06 25.7 0.1 8.9e-05 22.2 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KFH43258.1 - 0.0022 18.1 2.3 6.3 7.3 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat TIP120 PF08623.10 KFH43258.1 - 0.071 12.9 1.0 3.6 7.3 0.0 3.4 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) RICTOR_M PF14666.6 KFH43258.1 - 0.075 12.8 0.0 0.27 11.0 0.0 2.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 KFH43258.1 - 0.24 11.7 0.9 0.54 10.6 0.2 2.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Peptidase_M14 PF00246.24 KFH43259.1 - 9.6e-74 248.8 0.0 1.4e-73 248.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Fmp27_WPPW PF10359.9 KFH43260.1 - 0.29 10.0 2.9 0.45 9.3 2.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SlyX PF04102.12 KFH43260.1 - 1.3 9.7 9.0 0.3 11.7 2.9 2.7 2 1 0 2 2 2 0 SlyX ADIP PF11559.8 KFH43260.1 - 1.4 9.0 6.5 2.5 8.2 6.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OEP PF02321.18 KFH43260.1 - 8.5 6.1 13.1 0.12 12.2 5.9 1.5 2 0 0 2 2 2 0 Outer membrane efflux protein TFIIE_alpha PF02002.17 KFH43261.1 - 1.2e-14 54.0 0.2 2.3e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zinc-ribbons_6 PF07191.12 KFH43261.1 - 0.046 13.7 0.3 0.092 12.7 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-Dof PF02701.15 KFH43261.1 - 0.75 10.0 3.4 2.6 8.3 3.4 1.9 1 1 0 1 1 1 0 Dof domain, zinc finger SMC_N PF02463.19 KFH43262.1 - 1.6e-49 168.3 31.8 1.1e-48 165.6 31.8 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFH43262.1 - 2.6e-28 98.7 0.3 1.3e-27 96.4 0.0 2.5 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFH43262.1 - 3.3e-13 50.6 12.1 3.3e-13 50.6 12.1 6.5 3 2 2 5 5 3 1 AAA domain AAA_21 PF13304.6 KFH43262.1 - 3e-09 37.1 12.4 3.3e-05 23.8 0.5 4.1 3 3 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH43262.1 - 5.4e-08 32.5 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KFH43262.1 - 1.8e-07 31.2 13.9 1.8e-07 31.2 13.9 4.8 2 2 2 4 4 2 1 AAA ATPase domain MAD PF05557.13 KFH43262.1 - 0.00038 19.0 22.2 0.00038 19.0 22.2 5.2 4 1 1 5 5 5 2 Mitotic checkpoint protein AAA_13 PF13166.6 KFH43262.1 - 0.01 14.5 94.0 0.0031 16.3 30.3 6.0 3 2 1 5 5 5 0 AAA domain SbcCD_C PF13558.6 KFH43262.1 - 0.011 16.0 0.0 0.083 13.1 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Spc7 PF08317.11 KFH43262.1 - 8.8 5.1 119.3 0.25 10.2 2.2 7.2 3 2 5 8 8 8 0 Spc7 kinetochore protein DUF948 PF06103.11 KFH43262.1 - 9.1 6.6 36.0 2.5 8.4 0.6 7.4 6 2 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Ndufs5 PF10200.9 KFH43264.1 - 3.3e-05 24.1 0.0 4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KFH43264.1 - 0.014 15.7 0.7 0.12 12.8 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KFH43264.1 - 0.03 14.5 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb SNARE PF05739.19 KFH43265.1 - 8.2e-15 54.6 0.2 1.8e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFH43265.1 - 1.1e-05 25.2 15.8 0.00084 19.1 1.4 2.4 3 0 0 3 3 3 2 Syntaxin Syntaxin_2 PF14523.6 KFH43265.1 - 0.002 18.5 11.6 0.0099 16.2 3.8 2.4 3 0 0 3 3 3 2 Syntaxin-like protein Uds1 PF15456.6 KFH43265.1 - 0.018 15.2 0.1 0.018 15.2 0.1 2.4 2 1 1 3 3 3 0 Up-regulated During Septation MCPsignal PF00015.21 KFH43265.1 - 0.048 13.5 7.7 0.1 12.4 1.0 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GCP_C_terminal PF04130.13 KFH43265.1 - 0.16 11.4 1.8 0.23 10.9 1.1 1.6 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal Cauli_DNA-bind PF03310.13 KFH43265.1 - 0.29 11.2 5.3 0.11 12.6 1.2 2.2 2 1 1 3 3 3 0 Caulimovirus DNA-binding protein DASH_Dad1 PF08649.10 KFH43265.1 - 0.83 9.9 3.8 6.7 7.0 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 SlyX PF04102.12 KFH43265.1 - 2.5 8.8 7.5 1.1 10.0 0.5 3.2 3 1 1 4 4 4 0 SlyX SRP_TPR_like PF17004.5 KFH43266.1 - 1.2e-22 80.1 2.1 2.6e-21 75.8 0.8 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KFH43266.1 - 2.9e-15 56.4 11.2 2.9e-15 56.4 11.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain SPO22 PF08631.10 KFH43266.1 - 0.00085 18.9 0.7 0.04 13.4 0.0 3.0 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 KFH43266.1 - 0.0024 17.9 15.7 0.44 10.8 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH43266.1 - 0.0046 17.1 3.2 5.2 7.6 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH43266.1 - 0.0053 16.5 1.8 3.5 7.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43266.1 - 0.007 17.1 28.1 0.47 11.4 0.1 8.6 6 3 2 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH43266.1 - 0.0072 16.5 5.6 1.8 8.8 0.2 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFH43266.1 - 0.024 14.6 0.9 4.3 7.6 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFH43266.1 - 0.048 14.2 29.3 0.97 10.0 0.0 6.7 4 3 4 8 8 8 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 KFH43266.1 - 0.13 11.9 2.8 2.5 7.8 0.1 3.0 2 0 0 2 2 2 0 GGA N-GAT domain PPR PF01535.20 KFH43266.1 - 0.17 12.2 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.6 KFH43266.1 - 0.78 10.1 17.0 9.9 6.5 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH43266.1 - 1.8 9.4 11.7 1.4 9.8 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFH43266.1 - 3.3 8.1 10.6 10 6.5 0.0 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFH43266.1 - 5.1 7.3 12.6 13 6.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFH43266.1 - 6.5 7.7 14.5 6.3 7.7 0.3 5.5 7 0 0 7 7 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 KFH43268.1 - 1.2e-20 73.5 0.6 3.9e-12 46.2 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH43268.1 - 1.3e-15 57.3 2.7 3.1e-12 46.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Exonuc_X-T_C PF08411.10 KFH43268.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Exonuclease C-terminal Sec39 PF08314.11 KFH43269.1 - 1e-242 807.8 0.1 1.2e-242 807.6 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 ABC_membrane PF00664.23 KFH43270.1 - 1.7e-48 165.6 11.1 2.3e-48 165.2 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFH43270.1 - 3e-34 118.5 0.2 1.4e-33 116.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KFH43270.1 - 2.5e-05 23.8 0.1 0.00044 19.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFH43270.1 - 0.0015 18.8 0.2 0.012 15.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH43270.1 - 0.0051 17.2 2.0 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFH43270.1 - 0.011 16.1 0.7 0.12 12.8 0.2 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH43270.1 - 0.025 14.6 0.5 0.081 12.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KFH43270.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KFH43270.1 - 0.08 11.7 0.1 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KFH43270.1 - 0.087 12.6 0.1 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KFH43270.1 - 0.099 12.9 1.4 1.3 9.3 1.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PrgI PF12666.7 KFH43270.1 - 0.28 11.9 2.1 2.3 9.0 0.4 2.6 2 0 0 2 2 2 0 PrgI family protein DUF3987 PF13148.6 KFH43270.1 - 0.47 9.4 0.0 0.47 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Ribosomal_L11_N PF03946.14 KFH43271.1 - 2.7e-25 88.0 0.2 4.4e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFH43271.1 - 4.4e-17 62.3 0.3 7.7e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP_bind_3 PF01171.20 KFH43271.1 - 0.091 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 PP-loop family Sec7 PF01369.20 KFH43272.1 - 6.1e-29 101.0 0.0 9.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFH43272.1 - 4.8e-06 27.0 0.0 1.3e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFH43272.1 - 0.00013 22.3 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_transf_8 PF01501.20 KFH43273.1 - 2e-25 89.8 0.9 3.6e-24 85.7 0.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFH43273.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative RRM_1 PF00076.22 KFH43274.1 - 1.8e-20 72.5 0.0 2.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH43274.1 - 2.7e-05 23.8 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 KFH43275.1 - 9.5e-53 178.9 0.0 1.2e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFH43275.1 - 4.8e-13 50.2 0.1 6.1e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH43275.1 - 6.6e-10 39.1 0.4 3e-09 36.9 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH43275.1 - 0.0064 16.0 0.5 1.8 8.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFH43275.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 KFH43275.1 - 0.17 11.2 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1659 PF07872.11 KFH43276.1 - 2 8.2 4.8 10 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) MAPEG PF01124.18 KFH43277.1 - 1.6e-24 86.3 2.7 1.8e-24 86.1 2.7 1.0 1 0 0 1 1 1 1 MAPEG family Acetyltransf_1 PF00583.25 KFH43278.1 - 8.5e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH43278.1 - 8.9e-10 38.6 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH43278.1 - 1.9e-08 34.6 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH43278.1 - 8.8e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFH43278.1 - 0.00061 19.9 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Clathrin_lg_ch PF01086.17 KFH43279.1 - 2.5e-74 250.2 5.9 2.9e-74 250.0 5.9 1.0 1 0 0 1 1 1 1 Clathrin light chain CR6_interact PF10147.9 KFH43279.1 - 0.0054 16.5 4.4 0.0078 15.9 0.7 2.0 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 FKBP_N PF01346.18 KFH43279.1 - 0.29 12.1 4.5 0.81 10.7 4.5 1.7 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4407 PF14362.6 KFH43279.1 - 6 6.1 10.8 7.6 5.8 9.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-rbx1 PF12678.7 KFH43281.1 - 7.2e-10 39.0 3.8 1.4e-09 38.1 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFH43281.1 - 4.5e-08 33.3 5.7 1.1e-07 32.1 5.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH43281.1 - 2e-06 27.7 1.9 4.2e-06 26.7 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFH43281.1 - 3.4e-06 26.8 2.3 6.2e-06 26.0 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH43281.1 - 2.7e-05 23.9 5.6 0.00037 20.3 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH43281.1 - 0.0001 22.2 2.5 0.00031 20.6 2.6 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH43281.1 - 0.00078 19.2 3.4 0.00078 19.2 3.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFH43281.1 - 0.0013 18.7 0.6 0.0029 17.6 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFH43281.1 - 0.01 15.4 0.6 0.023 14.3 0.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ATP-synt_C PF00137.21 KFH43281.1 - 0.021 15.2 0.2 11 6.5 0.0 2.8 3 0 0 3 3 2 0 ATP synthase subunit C Prok-RING_4 PF14447.6 KFH43281.1 - 0.039 13.8 5.7 0.22 11.4 5.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFH43281.1 - 0.042 14.0 0.8 0.098 12.8 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFH43281.1 - 0.076 12.8 0.9 1 9.2 0.9 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KFH43281.1 - 0.14 12.0 3.1 0.1 12.4 0.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMP-TENI PF02581.17 KFH43281.1 - 0.14 11.5 1.4 0.26 10.6 1.4 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF5320 PF17253.2 KFH43281.1 - 0.23 12.6 0.2 0.23 12.6 0.2 2.4 2 1 0 2 2 1 0 Family of unknown function (DUF5320) FANCL_C PF11793.8 KFH43281.1 - 0.94 9.7 2.7 4.9 7.4 2.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain EMC3_TMCO1 PF01956.16 KFH43281.1 - 6.2 6.5 7.1 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like STAG PF08514.11 KFH43283.1 - 0.061 13.2 0.2 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 STAG domain Nop14 PF04147.12 KFH43283.1 - 0.15 10.3 0.0 0.27 9.4 0.0 1.6 1 1 1 2 2 2 0 Nop14-like family VPS28 PF03997.12 KFH43283.1 - 0.21 11.2 0.9 0.58 9.8 0.4 1.8 1 1 1 2 2 2 0 VPS28 protein CTD_bind PF04818.13 KFH43284.1 - 2.7e-16 60.1 0.1 8.9e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Transcrip_act PF04949.13 KFH43284.1 - 0.068 13.1 0.3 0.068 13.1 0.3 1.6 2 0 0 2 2 2 0 Transcriptional activator DUF4666 PF15697.5 KFH43284.1 - 0.07 13.8 0.2 0.18 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) CMV_1a PF12467.8 KFH43284.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DHR10 PF18595.1 KFH43284.1 - 0.32 11.1 4.9 0.14 12.2 1.7 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DIT1_PvcA PF05141.12 KFH43285.1 - 0.057 12.9 0.0 0.067 12.6 0.0 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4129 PF13559.6 KFH43285.1 - 0.067 13.5 1.7 0.32 11.3 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) EF-hand_1 PF00036.32 KFH43286.1 - 1.5e-41 136.8 12.9 8.5e-10 37.5 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFH43286.1 - 4.2e-36 123.2 5.8 4.4e-19 68.7 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFH43286.1 - 8.8e-35 118.3 12.0 2.6e-15 56.0 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFH43286.1 - 9.6e-31 103.1 8.1 2.1e-09 36.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFH43286.1 - 8.5e-26 88.3 10.6 2.8e-06 26.6 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFH43286.1 - 1.8e-16 60.2 0.4 2.6e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFH43286.1 - 4.8e-09 36.1 2.4 0.00081 19.3 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFH43286.1 - 5.5e-09 36.3 0.2 0.0017 18.6 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KFH43286.1 - 1.2e-06 28.4 0.0 0.0085 16.1 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFH43286.1 - 7e-06 26.0 1.6 2.6e-05 24.2 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KFH43286.1 - 0.00011 23.1 0.2 0.0025 18.7 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KFH43286.1 - 0.00015 21.7 0.6 0.38 10.7 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KFH43286.1 - 0.00056 19.9 1.7 0.48 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KFH43286.1 - 0.00069 19.9 0.8 0.6 10.4 0.2 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF5580 PF17743.1 KFH43286.1 - 0.0068 15.0 0.0 0.007 15.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 KFH43286.1 - 0.0083 16.3 7.7 0.44 10.8 0.9 3.1 1 1 3 4 4 4 2 Dockerin type I domain SurA_N_2 PF13623.6 KFH43286.1 - 0.012 15.5 1.0 0.51 10.2 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KFH43286.1 - 0.013 15.8 0.4 7.1 7.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KFH43286.1 - 0.018 15.2 0.0 0.15 12.3 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KFH43286.1 - 0.032 14.7 0.0 9.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) MotA_activ PF09114.10 KFH43286.1 - 0.067 13.3 0.3 1.3 9.2 0.0 2.4 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 KFH43286.1 - 0.068 13.6 0.1 9.3 6.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KFH43286.1 - 0.075 12.2 0.2 1.2 8.3 0.1 2.1 1 1 1 2 2 2 0 Cache domain RloB PF13707.6 KFH43286.1 - 0.16 12.1 1.3 0.91 9.7 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KFH43286.1 - 0.17 12.0 0.5 22 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) CorA PF01544.18 KFH43287.1 - 1.4e-15 57.4 0.2 2.6e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein POP1 PF06978.11 KFH43288.1 - 1.5e-72 243.9 10.4 1.5e-72 243.9 10.4 2.0 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFH43288.1 - 2.2e-29 101.6 1.0 4.8e-29 100.5 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KFH43288.1 - 0.19 11.0 0.0 0.56 9.5 0.0 1.7 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain MFS_1 PF07690.16 KFH43289.1 - 1.9e-42 145.5 42.3 5.8e-41 140.6 25.6 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43289.1 - 2.1e-16 59.9 3.3 2.1e-16 59.9 3.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFH43289.1 - 4.4e-07 28.7 6.6 6.2e-07 28.2 6.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFH43289.1 - 0.0005 19.5 1.8 0.0005 19.5 1.8 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KFH43289.1 - 0.00075 17.9 2.8 0.00075 17.9 2.8 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KFH43289.1 - 2.5 6.9 10.8 0.3 9.9 3.9 2.2 1 1 1 2 2 2 0 MFS_1 like family Acatn PF13000.7 KFH43290.1 - 7.7e-160 533.0 13.8 4.8e-82 276.2 7.3 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yip1 PF04893.17 KFH43291.1 - 0.0044 16.8 0.3 0.006 16.3 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain MIG-14_Wnt-bd PF06664.12 KFH43291.1 - 0.011 15.0 0.2 0.014 14.6 0.2 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion SLAC1 PF03595.17 KFH43291.1 - 0.012 14.9 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Shisa PF13908.6 KFH43291.1 - 0.049 13.9 0.6 4.7 7.4 0.0 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF4199 PF13858.6 KFH43291.1 - 0.12 12.8 3.7 0.18 12.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Rrp40_N PF18311.1 KFH43292.1 - 6.2e-18 64.5 1.2 2.1e-17 62.8 1.0 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KFH43292.1 - 2.1e-15 56.8 0.0 5.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 KH domain MFS_1 PF07690.16 KFH43293.1 - 4.2e-43 147.6 66.9 2.7e-38 131.8 42.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43293.1 - 9.9e-06 24.7 34.3 2.5e-05 23.4 9.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter GATA PF00320.27 KFH43294.1 - 1.9e-16 59.4 2.3 3.7e-16 58.4 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KFH43294.1 - 1.5e-10 40.7 0.1 3.1e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) IDH PF03971.14 KFH43294.1 - 0.0018 16.8 0.1 0.0027 16.3 0.1 1.1 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase Pyrid_oxidase_2 PF13883.6 KFH43296.1 - 9.7e-38 129.8 0.0 6.3e-36 123.9 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase fn3_2 PF16893.5 KFH43297.1 - 1.7e-39 133.9 0.0 2.7e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KFH43297.1 - 1.3e-22 79.4 1.0 2.2e-22 78.8 1.0 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KFH43297.1 - 1.2e-12 47.6 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KFH43297.1 - 5.4e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFH43297.1 - 4.5e-07 30.2 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KFH43297.1 - 0.0028 17.8 1.5 0.007 16.6 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3006) BUD22 PF09073.10 KFH43297.1 - 0.0036 16.7 26.0 0.0045 16.4 26.0 1.1 1 0 0 1 1 1 1 BUD22 fn3 PF00041.21 KFH43297.1 - 0.0054 17.0 0.0 0.025 14.9 0.0 2.1 1 1 0 1 1 1 1 Fibronectin type III domain LIG3_BRCT PF16759.5 KFH43297.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Mitofilin PF09731.9 KFH43297.1 - 7.7 5.2 26.7 10 4.8 26.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SEN1_N PF12726.7 KFH43300.1 - 4.9e-206 686.4 1.3 6.4e-206 686.0 1.3 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KFH43300.1 - 5.7e-73 245.9 0.3 5.7e-73 245.9 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KFH43300.1 - 3e-63 213.0 0.0 5.5e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH43300.1 - 2.7e-08 33.7 0.1 0.00016 21.5 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH43300.1 - 2.3e-07 31.3 0.2 2.6e-06 27.8 0.2 2.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFH43300.1 - 0.00023 21.0 0.2 0.23 11.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFH43300.1 - 0.021 15.1 0.0 0.13 12.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH43300.1 - 0.24 11.8 1.5 4.9 7.5 0.6 3.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_12 PF13087.6 KFH43301.1 - 8.4e-24 84.3 0.0 1.6e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH43301.1 - 8.9e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFH43301.1 - 1.8e-08 34.4 0.0 9.8e-07 28.7 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KFH43301.1 - 8.1e-08 32.0 0.1 2.3e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KFH43301.1 - 0.029 14.1 0.0 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Med12 PF09497.10 KFH43302.1 - 1.3e-27 95.8 1.3 1.2e-26 92.8 0.4 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KFH43302.1 - 9.5e-06 24.7 0.2 0.0011 17.9 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain TAN PF11640.8 KFH43302.1 - 0.013 15.6 0.0 0.091 12.9 0.0 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Yae1_N PF09811.9 KFH43303.1 - 4.1e-13 48.8 3.8 4.3e-13 48.7 2.3 1.8 1 1 1 2 2 2 1 Essential protein Yae1, N terminal DUF5316 PF17247.2 KFH43306.1 - 0.013 15.5 1.3 0.013 15.5 1.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5316) Phage_holin_2_3 PF16080.5 KFH43306.1 - 0.63 9.9 4.2 0.9 9.3 4.2 1.4 1 1 0 1 1 1 0 Bacteriophage holin family HP1 NT-C2 PF10358.9 KFH43307.1 - 3.1e-27 95.1 0.0 2.3e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SelP_N PF04592.14 KFH43307.1 - 2.1 7.7 12.2 3.3 7.1 12.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lyase_1 PF00206.20 KFH43308.1 - 7.3e-109 363.9 0.0 1.1e-108 363.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFH43308.1 - 2.7e-20 72.5 0.0 7.3e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus GFA PF04828.14 KFH43309.1 - 1.7e-13 50.7 1.7 2.3e-13 50.3 1.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DFP PF04127.15 KFH43310.1 - 3.9e-11 43.1 0.0 6.4e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Menin PF05053.13 KFH43310.1 - 7.3e-05 21.3 5.8 9.8e-05 20.9 5.8 1.1 1 0 0 1 1 1 1 Menin Zip PF02535.22 KFH43310.1 - 0.033 13.4 1.5 0.044 13.0 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 KFH43310.1 - 0.26 9.8 8.5 0.32 9.5 8.5 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KFH43310.1 - 0.48 9.1 6.9 0.66 8.7 6.9 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFH43310.1 - 3.7 6.3 5.8 5.2 5.8 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 KFH43310.1 - 4.1 6.1 11.4 5.6 5.6 11.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-O PF09496.10 KFH43311.1 - 9.8e-71 238.1 0.1 2.5e-70 236.8 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component PBP_N PF17093.5 KFH43311.1 - 0.11 12.7 2.1 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Uds1 PF15456.6 KFH43311.1 - 0.16 12.1 2.8 0.11 12.7 0.5 1.9 3 0 0 3 3 3 0 Up-regulated During Septation ABC_tran_CTD PF16326.5 KFH43311.1 - 1.6 9.0 6.7 0.31 11.3 1.0 2.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain Lipase_2 PF01674.18 KFH43312.1 - 1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 2) Hydrolase_4 PF12146.8 KFH43312.1 - 6.2e-05 22.4 0.0 8.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH43312.1 - 0.00011 22.0 0.1 0.0012 18.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KFH43312.1 - 0.00025 21.0 0.0 0.0067 16.3 0.0 2.0 1 1 1 2 2 2 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KFH43312.1 - 0.00079 18.8 0.0 0.063 12.6 0.0 2.9 2 1 2 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KFH43312.1 - 0.0013 18.3 0.1 0.0026 17.3 0.1 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFH43312.1 - 0.0021 18.7 0.1 0.0041 17.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KFH43312.1 - 0.0034 16.9 0.0 0.0069 15.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KFH43312.1 - 0.0062 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 KFH43312.1 - 0.007 16.2 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KFH43312.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 KFH43312.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-C2H2 PF00096.26 KFH43313.1 - 5.7e-09 36.0 21.5 0.0023 18.3 2.6 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH43313.1 - 0.012 16.4 23.4 0.024 15.4 1.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFH43313.1 - 0.018 15.6 9.0 0.13 12.9 1.2 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFH43313.1 - 0.02 15.1 0.4 0.02 15.1 0.4 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger DUF5518 PF17647.1 KFH43313.1 - 0.044 13.9 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Sina PF03145.16 KFH43313.1 - 3.9 7.4 11.9 2.5 8.0 9.7 1.7 1 1 1 2 2 2 0 Seven in absentia protein family Wbp11 PF09429.10 KFH43314.1 - 1.2e-23 83.3 13.3 1.2e-23 83.3 13.3 2.4 2 0 0 2 2 2 1 WW domain binding protein 11 PAG PF15347.6 KFH43314.1 - 0.013 14.6 1.4 0.021 13.9 1.4 1.4 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Lipoprotein_7 PF01540.16 KFH43314.1 - 2.8 7.2 10.6 0.064 12.5 3.7 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein eIF-1a PF01176.19 KFH43315.1 - 8.4e-21 73.6 0.0 1.2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 IBR PF01485.21 KFH43316.1 - 3.9e-14 52.6 26.7 8.6e-07 29.1 6.0 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KFH43316.1 - 0.00036 20.5 1.7 0.00036 20.5 1.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFH43316.1 - 0.0034 17.2 2.3 0.0034 17.2 2.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH43316.1 - 0.034 14.5 1.6 0.034 14.5 1.6 3.6 2 1 1 3 3 3 0 Ring finger domain DUF4446 PF14584.6 KFH43316.1 - 4.1 7.4 11.2 6.2 6.8 2.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Pkinase PF00069.25 KFH43317.1 - 7.7e-60 202.5 0.0 6.1e-59 199.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43317.1 - 9.4e-29 100.5 0.3 9.2e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFH43317.1 - 0.00063 20.4 1.4 0.00063 20.4 1.4 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFH43317.1 - 0.0039 16.6 0.7 0.012 15.0 0.0 2.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KFH43317.1 - 0.0078 16.2 1.0 0.14 12.0 0.1 3.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH43317.1 - 0.036 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFH43317.1 - 0.038 12.9 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Polysacc_lyase PF14099.6 KFH43318.1 - 2e-52 178.1 7.2 2.2e-52 177.9 7.2 1.0 1 0 0 1 1 1 1 Polysaccharide lyase adh_short PF00106.25 KFH43319.1 - 1.5e-10 40.9 0.0 6.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH43319.1 - 1.8e-08 34.2 0.0 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH43319.1 - 0.0017 18.3 0.2 0.0049 16.8 0.0 1.6 2 0 0 2 2 2 1 KR domain CAP_N PF01213.19 KFH43319.1 - 0.31 10.5 5.0 0.46 9.9 5.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFH43319.1 - 3.2 7.8 5.4 5.6 7.0 5.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4451 PF14616.6 KFH43320.1 - 0.0094 16.2 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF2654 PF10849.8 KFH43320.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) RhoGAP PF00620.27 KFH43322.1 - 7.6e-47 158.9 0.1 2.1e-46 157.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KFH43322.1 - 3.1e-13 49.8 0.1 9.4e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DED PF01335.21 KFH43322.1 - 0.042 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Death effector domain BBP1_C PF15272.6 KFH43322.1 - 0.077 12.8 4.8 0.1 12.4 3.6 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ERM PF00769.19 KFH43322.1 - 0.15 11.9 13.4 0.23 11.2 13.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DNA_methylase PF00145.17 KFH43323.1 - 3.2e-35 122.1 0.0 1.5e-26 93.6 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 KFH43323.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 EAF PF09816.9 KFH43325.1 - 4.3e-20 72.0 0.0 9.4e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cytomega_UL84 PF06284.11 KFH43325.1 - 0.62 8.5 4.8 0.99 7.8 4.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4185 PF13810.6 KFH43326.1 - 1.5e-69 234.7 1.2 1.9e-69 234.3 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) WH1 PF00568.23 KFH43328.1 - 5.8e-26 90.6 0.2 8e-26 90.2 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KFH43328.1 - 6.5e-05 22.6 0.3 0.00014 21.6 0.3 1.6 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 KFH43329.1 - 1.5e-19 70.7 0.0 5e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_2 PF12826.7 KFH43329.1 - 0.064 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KFH43329.1 - 0.17 12.5 0.0 1.5 9.5 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain HSP70 PF00012.20 KFH43330.1 - 3.2e-76 256.8 0.6 4.6e-76 256.3 0.6 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFH43330.1 - 1.3e-06 27.5 0.2 2.3e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 MreB/Mbl protein JAB PF01398.21 KFH43332.1 - 4.6e-33 113.7 0.0 8.4e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFH43332.1 - 9.2e-12 45.4 0.5 2.3e-11 44.1 0.5 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFH43332.1 - 1.6e-06 27.9 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Forkhead PF00250.18 KFH43333.1 - 5.8e-20 71.3 0.0 3.6e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Forkhead domain RNA_pol_Rpc34 PF05158.12 KFH43334.1 - 3.5e-98 329.1 0.0 4.6e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KFH43334.1 - 0.0068 17.0 0.8 0.054 14.2 0.0 2.8 4 0 0 4 4 4 1 Replication protein A C terminal Ribosomal_S25 PF03297.15 KFH43334.1 - 0.18 12.1 2.0 0.38 11.0 0.0 2.5 3 0 0 3 3 3 0 S25 ribosomal protein EndIII_4Fe-2S PF10576.9 KFH43334.1 - 0.59 10.6 2.1 1.1 9.7 2.1 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III ENTH PF01417.20 KFH43335.1 - 8.4e-46 155.1 0.1 1.2e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFH43335.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Cactin_mid PF10312.9 KFH43337.1 - 1.9e-61 207.3 9.0 2.6e-61 206.8 9.0 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KFH43337.1 - 6.3e-51 171.5 2.6 1.1e-50 170.8 2.6 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KFH43337.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 KFH43337.1 - 0.04 13.9 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) MMM1 PF10296.9 KFH43338.1 - 4.8e-06 25.9 0.0 8.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 FAM176 PF14851.6 KFH43338.1 - 4.7 6.9 6.5 8.6 6.0 0.3 2.5 2 0 0 2 2 2 0 FAM176 family Glyco_hydro_35 PF01301.19 KFH43340.1 - 6.7e-91 305.2 0.1 8.8e-91 304.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFH43340.1 - 9.7e-58 193.7 0.0 3.1e-33 114.8 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KFH43340.1 - 7e-57 192.2 1.5 1.1e-56 191.5 1.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KFH43340.1 - 2.5e-20 71.8 0.0 5.8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cep57_CLD_2 PF14197.6 KFH43341.1 - 1.1e-30 105.6 74.0 1.6e-16 60.1 12.4 6.7 5 2 1 7 7 6 4 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 KFH43341.1 - 1.1e-28 99.4 0.2 1.1e-28 99.4 0.2 6.0 5 2 0 5 5 5 1 Centrosome microtubule-binding domain of Cep57 GAS PF13851.6 KFH43341.1 - 0.00079 18.8 25.9 0.00079 18.8 25.9 5.4 3 2 2 5 5 5 2 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 KFH43341.1 - 0.00096 18.9 10.9 0.00096 18.9 10.9 6.4 5 1 2 7 7 6 2 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 KFH43341.1 - 0.00098 19.0 12.7 0.00098 19.0 12.7 5.9 3 1 2 5 5 4 3 Coiled-coil region of CCDC155 or KASH Mod_r PF07200.13 KFH43341.1 - 0.0012 19.0 8.4 0.0012 19.0 8.4 6.4 4 1 3 7 7 5 1 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 KFH43341.1 - 0.0018 18.4 3.7 0.0018 18.4 3.7 9.1 7 2 2 9 9 9 3 Homeobox associated leucine zipper DUF2353 PF09789.9 KFH43341.1 - 0.0026 17.2 20.3 0.0026 17.2 20.3 4.2 3 1 1 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) PRKG1_interact PF15898.5 KFH43341.1 - 0.0077 17.1 7.7 0.0077 17.1 7.7 7.3 4 2 3 7 7 5 2 cGMP-dependent protein kinase interacting domain DUF3220 PF11516.8 KFH43341.1 - 0.0093 16.2 0.1 0.26 11.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3120) ATG16 PF08614.11 KFH43341.1 - 0.01 16.1 22.0 0.01 16.1 22.0 7.2 5 3 1 6 6 5 0 Autophagy protein 16 (ATG16) SOAR PF16533.5 KFH43341.1 - 0.48 10.4 30.0 0.11 12.5 3.9 4.9 4 1 1 5 5 5 0 STIM1 Orai1-activating region RasGAP_C PF03836.15 KFH43341.1 - 1.5 9.0 0.0 1.5 9.0 0.0 7.0 5 2 1 7 7 7 0 RasGAP C-terminus CENP-F_leu_zip PF10473.9 KFH43341.1 - 7.1 6.6 59.2 2.6 8.1 16.3 5.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2206 PF09971.9 KFH43342.1 - 0.18 10.5 4.2 0.31 9.8 4.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Noc2 PF03715.13 KFH43343.1 - 2.7e-125 417.6 0.0 5.3e-125 416.6 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KFH43343.1 - 0.0035 15.6 0.1 0.0035 15.6 0.1 3.5 2 2 1 3 3 3 1 Nop14-like family CobN-Mg_chel PF02514.16 KFH43343.1 - 0.087 10.6 3.4 0.21 9.3 3.4 1.6 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Glyco_hydro_3_C PF01915.22 KFH43344.1 - 1.4e-61 208.0 0.0 3.4e-61 206.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH43344.1 - 3.2e-57 194.3 0.0 4.9e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KFH43344.1 - 7.7e-24 84.2 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 KFH43344.1 - 8.9e-23 80.2 0.0 1.9e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Metallophos PF00149.28 KFH43345.1 - 8.4e-08 32.9 6.8 2.8e-07 31.2 6.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S30 PF04758.14 KFH43346.1 - 1.7e-28 98.6 5.6 1.8e-28 98.5 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 XLF PF09302.11 KFH43347.1 - 7.5e-55 185.9 0.0 1.4e-54 185.0 0.0 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Pkinase PF00069.25 KFH43348.1 - 2.8e-73 246.6 0.0 4.1e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43348.1 - 1.6e-36 125.9 0.0 2.9e-36 125.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH43348.1 - 0.00011 21.6 0.5 0.49 9.7 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFH43348.1 - 0.0046 15.8 0.4 0.013 14.3 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFH43348.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family AbiEi_1 PF09407.10 KFH43349.1 - 0.068 13.5 0.2 0.19 12.1 0.2 1.7 1 1 0 1 1 1 0 AbiEi antitoxin C-terminal domain Hist_deacetyl PF00850.19 KFH43350.1 - 9.7e-75 251.9 0.3 1.8e-74 251.0 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Pro_isomerase PF00160.21 KFH43351.1 - 1.2e-42 145.9 0.4 1.5e-42 145.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MARVEL PF01284.23 KFH43352.1 - 1.1e-06 28.7 7.2 2.7e-06 27.5 7.3 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF3021 PF11457.8 KFH43352.1 - 0.0018 18.6 5.3 0.0056 17.0 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3021) Cation_efflux PF01545.21 KFH43352.1 - 1.3 8.7 10.4 0.65 9.7 6.6 2.1 1 1 1 2 2 2 0 Cation efflux family MgtE PF01769.16 KFH43352.1 - 4.5 7.7 10.8 18 5.7 8.0 2.2 2 1 0 2 2 2 0 Divalent cation transporter Cupin_1 PF00190.22 KFH43353.1 - 9.3e-42 142.2 0.0 1.5e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KFH43353.1 - 1e-26 92.4 0.8 2.5e-12 46.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFH43353.1 - 2e-08 33.8 0.1 0.00075 19.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFH43353.1 - 1.8e-07 31.1 0.2 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KFH43353.1 - 0.00085 19.2 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 KFH43353.1 - 0.019 15.1 0.3 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.7 KFH43353.1 - 0.051 13.5 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 ChrR Cupin-like domain 3-HAO PF06052.12 KFH43353.1 - 0.098 12.3 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase PIP5K PF01504.18 KFH43354.1 - 2.2e-32 112.4 1.4 1.6e-23 83.3 0.1 3.4 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFH43354.1 - 2.8e-26 92.2 0.0 4.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFH43354.1 - 2.9e-14 53.0 9.3 2.9e-14 53.0 9.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger Fungal_trans_2 PF11951.8 KFH43355.1 - 2.1e-49 168.4 0.0 2.7e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43355.1 - 4.3e-06 26.7 8.2 4.3e-06 26.7 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T3SS_needle_E PF08988.10 KFH43355.1 - 0.018 15.1 0.3 0.066 13.4 0.3 1.9 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle BolA PF01722.18 KFH43356.1 - 1.2e-29 102.4 0.1 1.8e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein VPS28 PF03997.12 KFH43358.1 - 5.1e-68 228.5 1.2 6.1e-68 228.2 1.2 1.1 1 0 0 1 1 1 1 VPS28 protein Cellulase PF00150.18 KFH43360.1 - 3e-16 59.7 0.1 3.8e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KFH43360.1 - 0.00016 21.4 0.1 0.0002 21.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KFH43360.1 - 0.0011 18.4 0.9 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KFH43360.1 - 0.064 12.4 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF1275 PF06912.11 KFH43361.1 - 7.9e-48 162.9 13.6 9.3e-48 162.7 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 KFH43361.1 - 4.6 7.2 6.9 14 5.6 0.7 2.6 2 1 0 2 2 2 0 PIG-P IF4E PF01652.18 KFH43364.1 - 1.7e-55 187.2 0.1 2.2e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANAPC_CDC26 PF10471.9 KFH43365.1 - 4.9e-12 46.5 7.1 4.9e-12 46.5 7.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 MAJIN PF15077.6 KFH43365.1 - 2.3 8.0 8.9 2.5 7.8 8.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Spem1 PF15670.5 KFH43365.1 - 3.1 7.3 8.0 3.5 7.1 7.7 1.2 1 1 0 1 1 1 0 Spermatid maturation protein 1 DUF4228 PF14009.6 KFH43365.1 - 5.4 7.4 9.9 6.2 7.2 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RRM_1 PF00076.22 KFH43366.1 - 2.7e-14 52.7 0.0 4.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KFH43367.1 - 4.4e-34 118.0 0.0 6.3e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43367.1 - 1.4e-17 63.8 0.0 4.4e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH43367.1 - 4.2e-05 23.0 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH43367.1 - 0.0094 15.9 0.4 0.047 13.6 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH43367.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFH43367.1 - 0.083 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family AMP-binding PF00501.28 KFH43369.1 - 1.9e-67 227.7 0.0 2.6e-65 220.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH43369.1 - 9.2e-13 49.0 0.4 2.2e-12 47.8 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyt-b5 PF00173.28 KFH43371.1 - 7.9e-13 48.4 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_P2_GpE PF06528.12 KFH43371.1 - 0.0003 20.3 2.1 0.00077 19.0 2.1 1.7 1 0 0 1 1 1 1 Phage P2 GpE Arm-DNA-bind_3 PF13356.6 KFH43371.1 - 0.3 11.5 1.5 7.3 7.1 1.4 2.4 1 1 0 1 1 1 0 Arm DNA-binding domain Voltage_CLC PF00654.20 KFH43372.1 - 2.1e-88 297.0 29.4 3.4e-88 296.3 29.4 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFH43372.1 - 4.4e-10 39.8 0.0 0.00084 19.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain TFIIA PF03153.13 KFH43373.1 - 2.7 7.9 42.4 4.3 7.2 42.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTB_2 PF02214.22 KFH43374.1 - 7.5e-05 23.0 0.0 0.0046 17.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L32p PF01783.23 KFH43375.1 - 1.7e-13 50.6 5.8 2.6e-13 50.0 5.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KFH43375.1 - 1.6 8.3 6.4 2.6 7.6 6.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain PAP2 PF01569.21 KFH43377.1 - 5.7e-19 68.2 2.4 1.9e-18 66.6 2.4 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFH43377.1 - 0.00026 20.8 3.0 0.00076 19.2 3.0 1.9 1 0 0 1 1 1 1 PAP2 superfamily Pkinase PF00069.25 KFH43378.1 - 1.7e-21 76.8 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KFH43378.1 - 6e-10 39.5 15.2 3.2e-05 24.6 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KFH43378.1 - 8.2e-10 38.1 4.5 0.27 11.6 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFH43378.1 - 2.7e-05 24.5 1.7 0.33 11.4 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KFH43378.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH43378.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Adaptin_N PF01602.20 KFH43378.1 - 0.024 13.2 0.1 1.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region ANAPC4_WD40 PF12894.7 KFH43378.1 - 0.084 13.2 0.1 0.72 10.2 0.1 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RTP1_C1 PF10363.9 KFH43378.1 - 0.23 11.7 1.5 7.1 6.8 0.1 3.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KFH43378.1 - 0.23 12.0 0.9 5.6 7.6 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat ThiF PF00899.21 KFH43379.1 - 5e-73 245.5 0.0 7.6e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KFH43379.1 - 1.6e-24 86.3 0.9 4.6e-23 81.6 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFH43379.1 - 1.4e-05 25.2 11.9 3.3e-05 23.9 0.9 3.1 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KFH43379.1 - 0.00044 20.6 0.1 0.0015 18.9 0.1 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFH43379.1 - 0.008 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFH43379.1 - 0.06 13.6 0.3 0.36 11.1 0.3 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pex14_N PF04695.13 KFH43379.1 - 1.1 9.9 14.8 0.13 12.9 10.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 KFH43379.1 - 7.5 5.3 16.4 14 4.4 16.4 1.3 1 0 0 1 1 1 0 Androgen receptor Glyco_hydro_76 PF03663.14 KFH43380.1 - 1.2e-147 492.2 1.7 1.5e-147 492.0 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFH43380.1 - 0.0002 20.6 7.0 0.015 14.4 0.0 3.2 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KFH43380.1 - 0.0036 16.6 0.2 0.59 9.3 0.0 2.4 1 1 1 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) CBFD_NFYB_HMF PF00808.23 KFH43381.1 - 1.5e-08 34.8 0.2 2.7e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EMP70 PF02990.16 KFH43382.1 - 1.6e-204 680.4 0.0 2e-204 680.1 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 KFH43382.1 - 6.1e-06 25.4 4.8 6.1e-06 25.4 4.8 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KFH43383.1 - 4.5e-59 199.8 0.7 5.9e-59 199.5 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43383.1 - 6.7e-45 152.9 0.9 9.3e-45 152.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH43383.1 - 5.7e-11 42.6 0.2 1e-10 41.8 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFH43383.1 - 0.0062 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFH43383.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_C58 PF03543.14 KFH43383.1 - 0.11 12.2 2.6 0.15 11.7 2.6 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen 3HCDH_N PF02737.18 KFH43383.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.14 KFH43384.1 - 1e-105 353.5 0.1 1.3e-105 353.2 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase BRCC36_C PF18110.1 KFH43386.1 - 0.006 16.7 0.3 0.047 13.8 0.2 2.6 1 1 1 2 2 2 1 BRCC36 C-terminal helical domain Fzo_mitofusin PF04799.13 KFH43386.1 - 0.079 12.5 0.2 0.079 12.5 0.2 4.7 3 1 1 5 5 5 0 fzo-like conserved region DUF4279 PF14106.6 KFH43386.1 - 0.73 10.1 5.5 0.63 10.3 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) DUF4363 PF14276.6 KFH43386.1 - 2.8 8.1 12.8 15 5.8 0.2 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Guanylate_kin PF00625.21 KFH43387.1 - 5.1e-58 195.8 0.0 5.7e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KFH43387.1 - 1.9e-05 25.2 0.0 3.6e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH43387.1 - 0.00068 20.1 0.1 0.0017 18.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFH43387.1 - 0.001 19.3 0.2 0.028 14.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFH43387.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFH43387.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFH43387.1 - 0.021 15.0 0.1 0.18 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF4914 PF16260.5 KFH43387.1 - 0.087 10.9 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) dNK PF01712.19 KFH43387.1 - 0.096 12.5 0.1 0.96 9.3 0.1 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase DOCK_N PF16172.5 KFH43388.1 - 6.3e-118 394.0 0.0 1.2e-117 393.0 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KFH43388.1 - 2.2e-36 125.6 3.4 8.4e-36 123.7 3.4 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KFH43388.1 - 4.9e-35 121.1 0.0 9.6e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFH43388.1 - 4.1e-05 23.1 0.0 9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH43388.1 - 0.00028 20.7 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain CENP-B_dimeris PF09026.10 KFH43388.1 - 0.007 16.7 8.0 0.018 15.4 8.0 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FAM176 PF14851.6 KFH43388.1 - 0.038 13.7 6.8 0.11 12.2 6.8 1.7 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 KFH43388.1 - 0.074 12.9 4.5 0.26 11.2 4.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Radial_spoke PF04712.12 KFH43388.1 - 0.083 11.8 4.3 0.14 11.1 4.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein SH3_2 PF07653.17 KFH43388.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain SERTA PF06031.13 KFH43388.1 - 0.14 11.9 0.0 0.48 10.1 0.0 1.9 1 0 0 1 1 1 0 SERTA motif RXT2_N PF08595.11 KFH43388.1 - 0.25 11.4 3.4 0.7 9.9 3.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.18 KFH43388.1 - 0.67 9.8 7.3 1.5 8.6 7.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 KFH43388.1 - 1.5 6.8 14.0 0.8 7.7 9.7 2.1 2 0 0 2 2 2 0 DNA polymerase phi CDC45 PF02724.14 KFH43388.1 - 2 6.6 6.0 3.5 5.8 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 KFH43388.1 - 2.1 7.9 9.7 0.1 12.2 2.9 2.3 3 0 0 3 3 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KFH43388.1 - 4.3 6.6 11.3 7.7 5.7 11.3 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 KFH43389.1 - 2.6e-21 75.5 11.8 1.3e-08 35.3 0.7 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43389.1 - 1e-13 51.4 0.7 0.0054 17.0 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH43389.1 - 0.00012 21.1 0.2 1.3 7.9 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFH43389.1 - 0.0012 18.7 0.0 0.055 13.3 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFH43389.1 - 0.0088 14.7 0.1 0.051 12.2 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFH43389.1 - 0.016 14.6 0.0 0.046 13.0 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain Nbas_N PF15492.6 KFH43389.1 - 0.025 13.9 0.1 2.9 7.2 0.0 2.9 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KFH43389.1 - 0.026 13.4 0.7 0.12 11.2 0.3 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain IceA2 PF05862.11 KFH43389.1 - 0.041 13.8 0.3 18 5.4 0.0 3.1 2 1 1 3 3 3 0 Helicobacter pylori IceA2 protein Hira PF07569.11 KFH43389.1 - 0.043 13.5 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split UFD1 PF03152.14 KFH43390.1 - 6.1e-68 227.7 0.0 7.7e-68 227.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Bul1_C PF04426.12 KFH43391.1 - 7.2e-05 22.3 0.0 0.00044 19.7 0.0 1.9 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.12 KFH43391.1 - 0.00017 20.5 0.0 0.003 16.4 0.0 2.2 1 1 0 1 1 1 1 Bul1 N terminus Mito_carr PF00153.27 KFH43392.1 - 4.9e-66 218.7 5.1 7.1e-24 83.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KFH43392.1 - 0.11 12.3 0.9 0.38 10.6 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) ATP-synt_C PF00137.21 KFH43393.1 - 4e-23 81.5 35.1 1.5e-13 50.9 10.5 2.6 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KFH43393.1 - 0.18 11.1 2.7 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3671 PF12420.8 KFH43393.1 - 0.27 11.3 2.5 0.35 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function EamA PF00892.20 KFH43394.1 - 0.00019 21.6 16.2 0.0076 16.4 16.2 2.1 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KFH43394.1 - 0.003 17.6 2.7 0.0039 17.2 2.7 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF2754 PF10953.8 KFH43394.1 - 0.074 13.3 3.1 0.71 10.2 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) US30 PF17624.2 KFH43394.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Ribosomal_S7 PF00177.21 KFH43395.1 - 6.9e-38 129.6 1.6 8.5e-38 129.3 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Spt5_N PF11942.8 KFH43396.1 - 0.019 15.9 11.9 2.3 9.2 10.7 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 KFH43396.1 - 0.048 14.1 5.0 0.075 13.4 5.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KFH43396.1 - 0.061 12.6 3.4 0.073 12.4 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein CRT10 PF08728.10 KFH43396.1 - 0.15 10.2 1.7 0.16 10.1 1.7 1.0 1 0 0 1 1 1 0 CRT10 FAM176 PF14851.6 KFH43396.1 - 0.38 10.4 4.3 0.57 9.8 4.3 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KFH43396.1 - 0.48 10.8 8.8 0.95 9.9 8.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 KFH43396.1 - 1.8 6.8 9.3 2.1 6.5 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_assoc2 PF16624.5 KFH43396.1 - 3 8.9 11.0 2.3 9.3 9.5 1.6 1 1 0 1 1 1 0 Unstructured region upstream of a zinc-finger RR_TM4-6 PF06459.12 KFH43396.1 - 3.6 7.3 8.1 4.2 7.1 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.11 KFH43399.1 - 0.00027 20.9 22.2 0.00027 20.9 22.2 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) DUF4191 PF13829.6 KFH43399.1 - 0.065 12.6 0.8 0.13 11.5 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) STAR_dimer PF16544.5 KFH43399.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Prominin PF05478.11 KFH43399.1 - 6.9 4.5 4.9 9.8 4.0 4.9 1.2 1 0 0 1 1 1 0 Prominin Glyco_hydro_17 PF00332.18 KFH43400.1 - 9.8e-09 35.2 0.1 1.1e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 WXG100 PF06013.12 KFH43400.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Rep_fac_C PF08542.11 KFH43402.1 - 1.2e-16 60.8 0.1 5.5e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KFH43402.1 - 1e-15 58.3 0.0 2.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFH43402.1 - 2.6e-11 43.6 0.6 4.7e-10 39.5 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KFH43402.1 - 1.8e-09 37.8 0.0 5.1e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KFH43402.1 - 3.2e-07 30.6 0.3 1.4e-06 28.5 0.0 2.3 3 0 0 3 3 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 KFH43402.1 - 7e-07 29.2 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 KFH43402.1 - 4.9e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFH43402.1 - 1.3e-05 25.5 0.0 8.7e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH43402.1 - 2.2e-05 24.4 0.1 0.00016 21.6 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH43402.1 - 3.2e-05 24.4 0.1 0.00025 21.5 0.0 2.3 1 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 KFH43402.1 - 6.5e-05 22.8 0.0 0.00047 20.0 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH43402.1 - 9.5e-05 22.4 0.1 0.00029 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFH43402.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFH43402.1 - 0.00016 21.4 0.1 0.00083 19.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KFH43402.1 - 0.00027 20.2 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KFH43402.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH43402.1 - 0.00092 19.6 0.1 0.0036 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFH43402.1 - 0.0037 16.7 0.1 0.061 12.7 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFH43402.1 - 0.0059 16.1 0.9 1.9 7.9 0.0 2.6 2 1 0 3 3 3 1 PhoH-like protein TniB PF05621.11 KFH43402.1 - 0.011 15.1 0.0 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KFH43402.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFH43402.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFH43402.1 - 0.032 14.2 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MCM PF00493.23 KFH43402.1 - 0.032 13.3 0.0 0.09 11.9 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain DUF1098 PF06497.11 KFH43402.1 - 0.037 14.5 0.1 0.56 10.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1098) AAA_7 PF12775.7 KFH43402.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TAFII28 PF04719.14 KFH43402.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 1 0 hTAFII28-like protein conserved region AAA_25 PF13481.6 KFH43402.1 - 0.055 13.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH43402.1 - 0.091 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 KFH43402.1 - 0.093 12.5 0.1 0.51 10.1 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase adh_short_C2 PF13561.6 KFH43404.1 - 6.3e-24 84.8 0.7 4.5e-16 59.1 0.5 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43404.1 - 2e-22 79.6 1.9 1.9e-21 76.4 1.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH43404.1 - 7.7e-08 32.4 0.6 1.9e-07 31.1 0.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH43404.1 - 0.024 14.1 0.1 0.38 10.2 0.0 2.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFH43404.1 - 0.06 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MoCF_biosynth PF00994.24 KFH43405.1 - 6.3e-54 181.6 0.6 5.5e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFH43405.1 - 8.2e-40 136.1 2.8 1.4e-39 135.4 2.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFH43405.1 - 2.2e-13 50.2 0.0 7.1e-13 48.5 0.0 2.0 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KFH43405.1 - 3.3 7.0 12.3 4.8 6.5 12.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LRR_9 PF14580.6 KFH43406.1 - 3.2e-53 179.8 0.0 5e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFH43406.1 - 9.4e-11 41.3 0.9 4.8e-10 39.1 0.3 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KFH43406.1 - 1.1e-08 35.3 7.7 2.4e-05 24.6 1.2 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 KFH43406.1 - 0.0036 16.8 2.5 0.0061 16.0 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KFH43406.1 - 0.023 14.7 1.8 51 4.3 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Q_salvage PF10343.9 KFH43407.1 - 2e-125 418.0 0.0 2.4e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4121 PF13497.6 KFH43407.1 - 0.038 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF1563 PF07599.11 KFH43407.1 - 0.092 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) cNMP_binding PF00027.29 KFH43409.1 - 1.4e-27 95.6 1.6 4.4e-15 55.5 0.1 5.9 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFH43409.1 - 3.9e-17 63.1 5.1 7.2e-16 59.0 5.1 2.8 1 1 0 1 1 1 1 Patatin-like phospholipase tRNA-synt_1d PF00750.19 KFH43410.1 - 1.4e-95 320.2 2.7 1.8e-95 319.9 2.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFH43410.1 - 1.6e-26 92.8 0.1 4.3e-26 91.4 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KFH43410.1 - 0.00011 22.7 0.0 0.00023 21.7 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 KFH43410.1 - 0.044 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 TFIIA_gamma_N PF02268.16 KFH43411.1 - 2.5e-24 85.0 0.3 3.5e-24 84.6 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KFH43411.1 - 1.3e-23 82.9 0.9 1.9e-23 82.3 0.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TIP49 PF06068.13 KFH43412.1 - 4e-152 506.4 0.7 5.2e-152 506.1 0.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFH43412.1 - 4e-23 81.3 0.9 1.4e-22 79.6 0.4 2.2 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA PF00004.29 KFH43412.1 - 5.3e-09 36.6 0.3 8.6e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH43412.1 - 1e-08 35.1 0.6 5.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KFH43412.1 - 8.3e-07 28.6 1.0 1.6e-06 27.7 1.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KFH43412.1 - 7e-06 26.5 0.6 2e-05 25.1 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KFH43412.1 - 0.0018 17.7 1.0 0.022 14.2 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFH43412.1 - 0.0037 17.5 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH43412.1 - 0.0052 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFH43412.1 - 0.01 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFH43412.1 - 0.027 14.2 0.0 9.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KFH43412.1 - 0.045 13.8 0.0 5 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KFH43412.1 - 0.076 12.8 0.5 0.3 10.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFH43412.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KFH43412.1 - 0.18 10.9 0.1 0.35 9.9 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DNA_pol_delta_4 PF04081.13 KFH43413.1 - 3.5e-46 156.8 4.4 6.8e-46 155.9 4.4 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 ATP_bind_1 PF03029.17 KFH43414.1 - 7.8e-78 261.6 0.0 9.8e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFH43414.1 - 0.0067 15.4 0.2 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KFH43414.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.6 KFH43414.1 - 0.052 13.5 0.0 2.5 8.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH43414.1 - 0.054 12.8 0.2 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin CLP1_P PF16575.5 KFH43414.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zip PF02535.22 KFH43415.1 - 2.7e-58 197.8 5.8 1.5e-57 195.4 5.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter GYF PF02213.16 KFH43416.1 - 6.8e-11 41.7 2.9 1.6e-10 40.5 2.9 1.7 1 0 0 1 1 1 1 GYF domain RNase_P_Rpp14 PF01900.19 KFH43417.1 - 1.4e-38 131.3 0.0 1.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Ribosomal_S25 PF03297.15 KFH43418.1 - 5.2e-38 129.3 2.9 5.6e-38 129.2 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KFH43418.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KFH43418.1 - 0.043 14.2 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Septin PF00735.18 KFH43419.1 - 3e-113 377.8 0.5 3.5e-113 377.6 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFH43419.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH43419.1 - 3.3e-06 26.8 0.4 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH43419.1 - 3.5e-06 27.0 0.1 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KFH43419.1 - 5.8e-06 25.8 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFH43419.1 - 0.0012 18.9 0.2 1.4 9.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 KFH43419.1 - 0.0045 17.3 0.0 0.01 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KFH43419.1 - 0.0077 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KFH43419.1 - 0.0087 15.6 0.1 0.057 12.9 0.0 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFH43419.1 - 0.01 16.2 0.0 0.035 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KFH43419.1 - 0.01 16.3 0.3 0.019 15.5 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 KFH43419.1 - 0.012 15.0 0.1 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFH43419.1 - 0.072 12.2 0.4 0.27 10.4 0.4 1.9 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KFH43419.1 - 0.073 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1542 PF07564.11 KFH43419.1 - 0.18 11.9 0.1 0.42 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) AAA_29 PF13555.6 KFH43419.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Acetyltransf_1 PF00583.25 KFH43420.1 - 0.00038 20.7 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KFH43420.1 - 0.00088 19.9 0.1 0.091 13.5 0.1 2.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH43420.1 - 0.0087 16.0 0.0 3.8 7.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH43420.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CENP-X PF09415.10 KFH43421.1 - 8.5e-23 80.5 0.1 8.5e-23 80.5 0.1 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X ASD2 PF08687.11 KFH43421.1 - 0.038 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CBFD_NFYB_HMF PF00808.23 KFH43421.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.17 KFH43423.1 - 3.8e-29 101.1 0.7 6.3e-29 100.4 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding UNC45-central PF11701.8 KFH43425.1 - 1.3e-55 187.5 0.0 4.2e-55 185.9 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KFH43425.1 - 2.2 8.5 12.5 24 5.1 0.1 6.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DFRP_C PF16543.5 KFH43426.1 - 2.2e-26 92.1 10.3 2.2e-26 92.1 10.3 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KFH43426.1 - 2.7e-06 27.2 0.9 2.7e-06 27.2 0.9 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFH43426.1 - 8.2e-06 26.5 3.1 8.2e-06 26.5 3.1 3.9 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 KFH43426.1 - 3.2e-05 23.6 7.6 0.0022 17.8 2.1 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFH43426.1 - 0.00011 22.1 6.8 0.00011 22.1 6.8 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 KFH43426.1 - 0.012 15.9 2.9 0.37 11.0 1.5 2.6 2 1 0 2 2 2 0 Zinc-finger containing family PTPS PF01242.19 KFH43426.1 - 0.017 15.1 0.4 4 7.4 0.1 2.5 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-CCCH_2 PF14608.6 KFH43426.1 - 0.038 14.5 13.6 0.42 11.2 5.5 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Amino_oxidase PF01593.24 KFH43427.1 - 4.7e-24 85.5 0.1 7.7e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH43427.1 - 2.6e-10 40.4 0.1 5.7e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH43427.1 - 2.4e-05 24.1 0.3 0.0062 16.2 0.0 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH43427.1 - 9e-05 21.8 0.0 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH43427.1 - 0.00016 21.7 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KFH43427.1 - 0.0057 15.4 0.0 0.57 8.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KFH43427.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH43427.1 - 0.031 13.4 0.0 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KFH43427.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFH43427.1 - 0.099 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Tcf25 PF04910.14 KFH43428.1 - 1.2e-62 212.1 0.0 1.6e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Pex19 PF04614.12 KFH43428.1 - 1.3 8.8 8.6 0.18 11.6 4.4 1.8 2 0 0 2 2 2 0 Pex19 protein family CS PF04969.16 KFH43429.1 - 3.2e-08 34.5 0.0 4.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 CS domain V-SNARE PF05008.15 KFH43430.1 - 5.8e-23 81.1 2.2 5.8e-23 81.1 2.2 2.1 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KFH43430.1 - 1e-16 61.0 2.6 1e-16 61.0 2.6 2.7 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.18 KFH43430.1 - 0.0061 14.9 1.3 0.017 13.4 0.2 2.0 2 0 0 2 2 2 1 Fusion glycoprotein F0 Sec20 PF03908.13 KFH43430.1 - 0.011 15.6 1.5 0.018 14.9 0.4 2.0 2 2 0 2 2 2 0 Sec20 Prominin PF05478.11 KFH43430.1 - 0.02 12.9 1.0 1.7 6.5 0.3 2.1 2 0 0 2 2 2 0 Prominin FAM219A PF15260.6 KFH43430.1 - 0.086 13.2 0.8 0.19 12.1 0.8 1.6 1 0 0 1 1 1 0 Protein family FAM219A FAM76 PF16046.5 KFH43430.1 - 0.17 11.2 1.1 0.19 11.0 0.1 1.5 2 0 0 2 2 2 0 FAM76 protein YqjK PF13997.6 KFH43430.1 - 0.2 11.9 2.0 1.9 8.8 0.1 2.6 3 0 0 3 3 3 0 YqjK-like protein Exonuc_VII_L PF02601.15 KFH43430.1 - 0.67 9.5 6.6 3.9 7.0 6.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Synaptobrevin PF00957.21 KFH43430.1 - 0.85 9.5 6.5 1.4 8.7 2.2 2.5 1 1 0 2 2 2 0 Synaptobrevin SNARE PF05739.19 KFH43430.1 - 4.3 7.4 8.5 0.41 10.7 2.0 2.7 4 1 0 4 4 4 0 SNARE domain Cutinase PF01083.22 KFH43431.1 - 5.2e-44 150.3 0.0 6.5e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFH43431.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KFH43431.1 - 0.00017 21.6 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 KFH43431.1 - 0.0064 16.1 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 KFH43431.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 60KD_IMP PF02096.20 KFH43432.1 - 7.1e-06 26.0 0.0 9.6e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein CtaG_Cox11 PF04442.14 KFH43433.1 - 7.5e-60 201.3 0.1 9e-60 201.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF4129 PF13559.6 KFH43434.1 - 0.0011 19.1 0.2 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) NDUF_B5 PF09781.9 KFH43434.1 - 0.17 11.5 0.5 0.31 10.6 0.5 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit NICE-3 PF07406.11 KFH43434.1 - 0.44 10.5 0.0 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 NICE-3 protein AgrB PF04647.15 KFH43434.1 - 0.46 9.8 7.7 0.7 9.2 7.7 1.2 1 0 0 1 1 1 0 Accessory gene regulator B 7tm_7 PF08395.12 KFH43434.1 - 2.7 7.1 9.1 4.1 6.5 9.1 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Thiolase_N PF00108.23 KFH43437.1 - 2.7e-15 56.4 0.0 1e-14 54.5 0.0 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH43437.1 - 2e-10 40.4 0.9 4.7e-10 39.2 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFH43437.1 - 4e-06 26.6 0.2 0.00017 21.4 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KFH43437.1 - 0.011 14.5 0.6 0.053 12.2 0.2 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KFH43437.1 - 0.022 14.3 1.3 0.048 13.2 1.3 1.6 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFH43437.1 - 0.028 14.4 1.2 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Mito_carr PF00153.27 KFH43438.1 - 1.1e-38 131.0 8.7 1.6e-14 53.6 0.3 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein AT_hook PF02178.19 KFH43439.1 - 0.015 15.1 20.6 0.032 14.1 3.0 3.5 3 0 0 3 3 3 0 AT hook motif tRNA_U5-meth_tr PF05958.11 KFH43440.1 - 2.9e-11 43.0 0.0 9.4e-10 38.0 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KFH43440.1 - 8.3e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KFH43440.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43440.1 - 0.00025 21.7 0.0 0.00051 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFH43440.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KFH43440.1 - 0.11 13.2 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFH43440.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) VEK-30 PF12107.8 KFH43441.1 - 0.84 9.6 5.5 2 8.4 5.5 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Prefoldin_2 PF01920.20 KFH43442.1 - 3.2e-24 84.9 9.3 4e-24 84.6 9.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit ADH_N PF08240.12 KFH43443.1 - 1.1e-28 99.3 0.4 1.9e-28 98.5 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43443.1 - 4.4e-21 75.2 0.1 7.5e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43443.1 - 0.0018 19.3 0.1 0.0028 18.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1967 PF09269.11 KFH43443.1 - 0.05 13.5 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) adh_short PF00106.25 KFH43443.1 - 0.074 12.5 0.3 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KFH43443.1 - 0.21 10.9 0.4 0.47 9.8 0.2 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UQ_con PF00179.26 KFH43444.1 - 2.1e-06 27.5 0.0 4e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase_fungal PF17667.1 KFH43445.1 - 7.1e-134 446.6 0.0 8.8e-134 446.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFH43445.1 - 1.6e-05 24.4 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFH43445.1 - 0.019 14.4 0.0 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH43445.1 - 0.027 14.4 1.5 0.041 13.8 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family MauJ PF17419.2 KFH43445.1 - 0.034 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Mcl1_mid PF12341.8 KFH43446.1 - 4.2e-99 331.6 0.0 1.8e-97 326.3 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFH43446.1 - 2.1e-14 53.7 1.0 3.3e-08 34.1 0.0 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43446.1 - 4.2e-11 43.0 0.0 0.00034 20.9 0.0 5.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFH43446.1 - 0.00014 21.0 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 KFH43446.1 - 0.0071 16.2 0.2 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFH43446.1 - 0.083 11.8 0.0 2 7.3 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_Ag35 PF03286.14 KFH43446.1 - 0.17 11.7 3.2 0.36 10.6 3.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIIC_delta PF12657.7 KFH43446.1 - 0.23 11.4 0.6 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term ABATE PF07336.11 KFH43446.1 - 2.9 8.6 6.8 0.61 10.8 1.3 2.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Tfb4 PF03850.14 KFH43447.1 - 1.3e-93 313.5 0.0 1.6e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Rogdi_lz PF10259.9 KFH43447.1 - 0.029 13.8 0.7 0.05 13.1 0.1 1.7 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Ost4 PF10215.9 KFH43448.1 - 6.2e-17 61.1 1.7 8.4e-17 60.7 1.7 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Syntaxin_2 PF14523.6 KFH43449.1 - 1.2e-22 80.1 7.4 1.2e-22 80.1 7.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFH43449.1 - 4.6e-14 52.1 0.5 4.6e-14 52.1 0.5 2.0 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 KFH43449.1 - 0.0074 16.1 0.4 0.018 14.8 0.4 1.7 1 0 0 1 1 1 1 Synaptobrevin Syntaxin PF00804.25 KFH43449.1 - 0.019 14.7 1.8 0.019 14.7 1.8 2.7 3 1 0 3 3 3 0 Syntaxin Vac_Fusion PF02346.16 KFH43449.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF883 PF05957.13 KFH43449.1 - 0.12 13.0 0.2 0.12 13.0 0.2 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF5345 PF17280.2 KFH43449.1 - 1.4 8.9 4.7 7.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF16 PF01519.16 KFH43449.1 - 4 8.0 13.9 0.94 10.0 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KFH43449.1 - 4.9 7.2 8.8 13 5.8 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KFH43449.1 - 5.7 7.6 7.2 11 6.8 0.2 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 KFH43449.1 - 9.8 6.3 13.5 1 9.4 6.7 2.4 2 2 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Snf7 PF03357.21 KFH43450.1 - 1.7e-18 66.8 7.6 1.7e-18 66.8 7.6 2.0 2 0 0 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 KFH43450.1 - 0.032 14.8 6.0 0.032 14.8 6.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cutinase PF01083.22 KFH43451.1 - 1.5e-29 103.2 0.0 1.8e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KFH43451.1 - 0.00094 19.1 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KFH43451.1 - 0.0055 16.3 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFH43451.1 - 0.011 16.4 0.1 0.011 16.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFH43451.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase FSH1 PF03959.13 KFH43451.1 - 0.098 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KFH43451.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 KFH43451.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase RRM_1 PF00076.22 KFH43452.1 - 2.3e-16 59.4 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH43452.1 - 0.00096 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 KFH43452.1 - 0.0056 17.2 1.8 0.0056 17.2 1.8 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Smg8_Smg9 PF10220.9 KFH43453.1 - 0.17 10.2 0.6 0.3 9.4 0.6 1.3 1 0 0 1 1 1 0 Smg8_Smg9 Ribosomal_60s PF00428.19 KFH43454.1 - 0.018 15.6 0.7 0.018 15.6 0.7 4.2 3 1 1 4 4 4 0 60s Acidic ribosomal protein SET PF00856.28 KFH43455.1 - 0.012 16.0 0.1 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 SET domain DUF412 PF04217.13 KFH43455.1 - 0.14 12.0 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF4407 PF14362.6 KFH43455.1 - 0.19 11.0 3.1 0.26 10.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUIM_assoc PF16619.5 KFH43455.1 - 0.27 11.3 7.0 0.55 10.3 7.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 KFH43456.1 - 6.4e-15 55.3 9.8 0.002 18.9 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1499 PF07386.11 KFH43456.1 - 0.044 14.4 0.9 1.4 9.5 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1499) BUD22 PF09073.10 KFH43457.1 - 0.088 12.1 32.6 0.19 11.1 14.8 2.1 2 0 0 2 2 2 0 BUD22 RNA_pol_Rpc4 PF05132.14 KFH43457.1 - 0.34 11.3 7.0 0.059 13.8 0.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nop14 PF04147.12 KFH43457.1 - 0.37 8.9 38.4 0.25 9.5 10.2 2.0 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 KFH43457.1 - 1.5 8.2 39.5 0.19 11.1 7.6 2.1 2 0 0 2 2 2 0 SDA1 SpoIIIAH PF12685.7 KFH43457.1 - 3.3 7.5 13.7 0.71 9.7 5.9 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein SAPS PF04499.15 KFH43457.1 - 8 5.1 10.2 3.6 6.3 4.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Thr_synth_N PF14821.6 KFH43458.1 - 2.3e-28 98.2 0.0 2e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KFH43458.1 - 1.4e-19 70.6 0.0 1.6e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ALG11_N PF15924.5 KFH43459.1 - 7.7e-83 277.6 0.0 1.1e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFH43459.1 - 2.7e-22 79.1 0.0 4.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH43459.1 - 4.6e-12 46.5 0.0 9.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFH43459.1 - 0.00011 22.2 0.4 0.00035 20.6 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Meth_synt_2 PF01717.18 KFH43460.1 - 5.3e-151 502.4 0.0 3.2e-146 486.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFH43460.1 - 3.2e-120 401.4 0.0 4.1e-113 378.0 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFH43460.1 - 0.019 14.1 0.0 0.097 11.8 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.10 KFH43460.1 - 0.12 12.5 1.6 0.47 10.6 1.6 2.0 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) LSM14 PF12701.7 KFH43461.1 - 1.8e-31 108.0 0.1 2.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFH43461.1 - 2.7e-23 82.8 0.9 2.7e-23 82.8 0.9 1.7 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFH43461.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_1 PF07690.16 KFH43462.1 - 6.3e-39 133.9 40.3 6.3e-39 133.9 40.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43462.1 - 2.7e-13 49.6 9.3 2.7e-13 49.6 9.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 KFH43462.1 - 8e-05 21.6 1.8 0.00022 20.2 1.8 1.7 1 0 0 1 1 1 1 POT family HMA PF00403.26 KFH43463.1 - 1.1e-12 48.2 1.4 9.2e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 Heavy-metal-associated domain G_glu_transpept PF01019.21 KFH43464.1 - 1.3e-159 532.3 0.2 7.6e-159 529.8 0.2 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase CBFD_NFYB_HMF PF00808.23 KFH43465.1 - 7.2e-05 23.0 0.1 9.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KFH43465.1 - 0.00011 22.4 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein PRO8NT PF08082.11 KFH43465.1 - 0.1 12.6 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Ndc1_Nup PF09531.10 KFH43466.1 - 2e-194 647.8 0.0 2.4e-194 647.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Actin PF00022.19 KFH43467.1 - 1.6e-87 293.8 0.0 2.8e-85 286.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFH43467.1 - 0.019 13.8 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KFH43468.1 - 3.5e-43 147.8 4.3 2.9e-28 98.8 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Acetyltransf_1 PF00583.25 KFH43471.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH43471.1 - 1.2e-07 31.7 0.0 6.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH43471.1 - 2.7e-07 30.9 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH43471.1 - 5.1e-06 26.4 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFH43471.1 - 2.5e-05 25.0 0.0 5.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFH43471.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFH43471.1 - 0.053 13.6 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIA PF03153.13 KFH43472.1 - 6.7e-95 319.5 19.2 8.4e-95 319.2 19.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 KFH43472.1 - 0.007 16.5 1.4 0.0086 16.3 1.4 1.3 1 0 0 1 1 1 1 DDHD domain SOG2 PF10428.9 KFH43472.1 - 1 8.5 14.3 1.2 8.2 14.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KFH43472.1 - 1.1 8.0 9.7 1.5 7.5 9.7 1.2 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 KFH43472.1 - 2.3 7.9 6.3 4.1 7.1 6.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FYDLN_acid PF09538.10 KFH43472.1 - 9.9 6.9 12.1 8.2 7.2 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Kelch_4 PF13418.6 KFH43474.1 - 1.8e-32 111.1 6.8 1.3e-08 34.7 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFH43474.1 - 7.4e-26 89.7 1.8 4.1e-07 29.9 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KFH43474.1 - 4.2e-25 87.1 2.7 3.2e-05 24.1 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KFH43474.1 - 7.6e-22 76.4 1.8 5.7e-06 26.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KFH43474.1 - 1e-20 73.0 0.9 0.00022 20.7 0.0 5.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KFH43474.1 - 1.2e-19 70.1 7.6 4.7e-07 29.9 0.2 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 KFH43474.1 - 6.4e-09 36.0 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PH_6 PF15406.6 KFH43475.1 - 4.7e-40 136.4 1.7 4.7e-40 136.4 1.7 3.8 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KFH43475.1 - 0.0041 17.6 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 PH domain SUR7 PF06687.12 KFH43476.1 - 1.1e-32 113.4 0.6 1.4e-32 113.1 0.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family HATPase_c PF02518.26 KFH43477.1 - 5.2e-23 81.7 0.1 1.3e-22 80.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH43477.1 - 1.1e-21 77.1 0.2 4.2e-21 75.2 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 KFH43477.1 - 4.9e-08 33.2 0.0 0.00015 22.0 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFH43477.1 - 1.8e-07 31.4 0.1 2.8e-06 27.5 0.0 3.0 3 1 1 4 4 4 1 PAS domain HisKA PF00512.25 KFH43477.1 - 6.8e-07 29.2 0.1 2.2e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KFH43477.1 - 6.8e-06 26.4 0.0 0.096 13.0 0.0 2.8 2 0 0 2 2 2 2 GAF domain PAS PF00989.25 KFH43477.1 - 6.8e-05 22.8 0.0 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 KFH43477.1 - 0.004 17.4 0.3 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.6 KFH43477.1 - 0.0043 17.4 0.0 0.024 15.0 0.0 2.2 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 KFH43477.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 KFH43477.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L36 PF00444.18 KFH43478.1 - 3.8e-22 78.2 11.5 5.6e-22 77.7 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Molybdopterin PF00384.22 KFH43478.1 - 0.049 12.6 0.0 0.058 12.4 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Ribosomal_L35p PF01632.19 KFH43478.1 - 0.41 11.2 5.3 1.1 9.8 5.3 1.8 1 1 0 1 1 1 0 Ribosomal protein L35 ADH_N PF08240.12 KFH43479.1 - 2.7e-27 94.8 2.3 4.8e-27 94.0 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43479.1 - 7.8e-16 58.2 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH43479.1 - 0.00026 20.5 0.9 0.074 12.5 0.5 2.9 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPGP PF01704.18 KFH43480.1 - 1.1e-56 192.3 0.0 1.3e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFH43480.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 KFH43480.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster fn3 PF00041.21 KFH43481.1 - 1.5e-07 31.6 0.0 4.9e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Jnk-SapK_ap_N PF09744.9 KFH43481.1 - 0.00064 20.0 17.0 0.00064 20.0 17.0 2.7 1 1 1 2 2 2 2 JNK_SAPK-associated protein-1 T2SSF PF00482.23 KFH43481.1 - 0.11 12.4 2.4 0.26 11.3 1.4 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1421 PF07223.11 KFH43482.1 - 0.011 15.5 0.1 0.02 14.7 0.0 1.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) RRF PF01765.19 KFH43483.1 - 1.1e-33 116.5 0.4 1.5e-33 116.1 0.4 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Nup88 PF10168.9 KFH43483.1 - 0.21 9.3 5.8 0.28 8.9 5.8 1.1 1 0 0 1 1 1 0 Nuclear pore component ATP-synt_B PF00430.18 KFH43483.1 - 0.44 10.6 7.4 0.7 10.0 7.4 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DSPc PF00782.20 KFH43484.1 - 3.5e-14 52.8 0.0 2.1e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFH43484.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Histidinol_dh PF00815.20 KFH43485.1 - 8e-160 532.3 4.4 8e-160 532.3 4.4 1.4 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 KFH43485.1 - 7.5e-24 83.4 0.0 1.7e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KFH43485.1 - 6e-13 49.0 0.2 1.4e-12 47.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Cas_Csx9 PF09658.10 KFH43485.1 - 0.058 12.6 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) ANAPC4_WD40 PF12894.7 KFH43488.1 - 2.2e-17 63.1 6.3 1.1e-05 25.7 0.2 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFH43488.1 - 4.4e-16 59.0 19.0 0.00033 21.4 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFH43488.1 - 2.5e-06 26.7 0.0 0.00027 20.0 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFH43488.1 - 1e-05 25.5 0.6 0.0014 18.5 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KFH43488.1 - 0.058 12.3 0.8 0.87 8.4 0.7 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Mitoc_mL59 PF18126.1 KFH43489.1 - 0.73 10.1 3.2 2.6 8.4 3.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 zf-C2H2_aberr PF17017.5 KFH43490.1 - 2.9e-05 24.3 1.6 0.012 15.8 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KFH43490.1 - 4.1e-05 23.8 10.0 0.11 12.9 0.5 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH43490.1 - 0.002 18.8 10.7 0.9 10.5 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH43490.1 - 0.044 14.1 1.5 3.2 8.1 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFH43490.1 - 0.074 13.5 0.8 0.074 13.5 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Phosphoprotein PF00922.17 KFH43490.1 - 0.099 12.2 0.5 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-C2H2_6 PF13912.6 KFH43490.1 - 3.1 7.9 10.2 0.55 10.3 1.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger IMPDH PF00478.25 KFH43491.1 - 1.4e-127 425.5 2.2 1.6e-127 425.3 2.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFH43491.1 - 7.3e-17 61.6 0.2 2.2e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KFH43491.1 - 6.8e-08 31.9 1.1 1.2e-06 27.8 0.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KFH43491.1 - 1.1e-06 28.3 2.8 0.025 14.0 3.6 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KFH43491.1 - 0.0023 17.5 2.2 0.036 13.5 0.3 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein YpsA PF06908.11 KFH43491.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 KFH43491.1 - 0.063 12.6 0.8 0.15 11.3 0.3 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG WD40 PF00400.32 KFH43492.1 - 1.8e-12 47.5 13.4 7.2e-05 23.5 0.0 8.8 10 1 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43492.1 - 0.014 15.7 0.0 8.2 6.8 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFH43492.1 - 0.06 12.1 0.4 3.6 6.2 0.0 3.3 5 0 0 5 5 5 0 Nup133 N terminal like FA_hydroxylase PF04116.13 KFH43493.1 - 2.3e-24 86.2 12.2 2.3e-24 86.2 12.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Calmodulin_bind PF07887.11 KFH43494.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like ATP-synt_G PF04718.15 KFH43495.1 - 2e-35 121.6 1.3 3.6e-35 120.8 0.3 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Senescence PF06911.12 KFH43495.1 - 0.0084 16.4 0.5 0.011 16.1 0.5 1.2 1 0 0 1 1 1 1 Senescence-associated protein Complex1_LYR PF05347.15 KFH43497.1 - 5.6e-21 74.3 0.1 8.1e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFH43497.1 - 9.3e-08 32.7 0.1 2e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 Complex1_LYR-like Glyco_transf_8C PF08437.10 KFH43497.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Trypsin PF00089.26 KFH43498.1 - 4.7e-67 226.0 2.4 5.3e-67 225.9 2.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFH43498.1 - 4.5e-09 37.4 4.2 7.2e-09 36.7 4.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KFH43498.1 - 0.035 13.3 3.3 0.091 11.9 0.7 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Aldedh PF00171.22 KFH43499.1 - 8.7e-167 555.3 0.1 9.8e-167 555.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFH43499.1 - 0.023 14.2 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) LNS2 PF08235.13 KFH43500.1 - 4.3e-94 314.2 0.0 6.1e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFH43500.1 - 1.9e-43 146.6 0.0 6.6e-43 144.8 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KFH43500.1 - 0.0015 18.2 0.0 0.087 12.4 0.0 2.4 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-MYND PF01753.18 KFH43501.1 - 1.2e-07 31.7 3.0 2.3e-07 30.8 3.0 1.5 1 0 0 1 1 1 1 MYND finger Metallophos PF00149.28 KFH43502.1 - 3.5e-35 122.4 0.0 5.2e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFH43502.1 - 5.1e-17 62.1 0.0 9.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIID-31kDa PF02291.15 KFH43503.1 - 6e-42 142.6 0.0 8e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Mucin PF01456.17 KFH43503.1 - 0.83 9.6 9.9 0.33 10.9 4.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.25 KFH43505.1 - 6.1e-09 35.6 0.0 7.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43505.1 - 4.1e-06 26.3 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH43505.1 - 0.003 17.5 1.1 0.02 14.8 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH43505.1 - 0.0059 15.9 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like NAPRTase_N PF17767.1 KFH43505.1 - 0.02 15.2 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Kdo PF06293.14 KFH43505.1 - 0.03 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2CSK_N PF08521.10 KFH43505.1 - 0.13 12.3 0.0 17 5.5 0.0 2.1 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal Pyr_redox_2 PF07992.14 KFH43506.1 - 3.6e-19 69.1 0.0 7.9e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH43506.1 - 7.5e-07 28.7 0.0 0.004 16.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH43506.1 - 1.6e-06 28.2 0.1 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KFH43506.1 - 1.9e-06 27.3 0.3 0.014 14.5 0.1 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 KFH43506.1 - 3.4e-05 22.7 0.0 0.0074 15.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KFH43506.1 - 4.3e-05 22.7 0.0 0.033 13.2 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KFH43506.1 - 6.8e-05 22.6 1.3 0.053 13.1 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFH43506.1 - 0.00055 19.2 0.1 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KFH43506.1 - 0.0015 17.7 0.2 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFH43506.1 - 0.0025 18.0 0.2 0.0053 17.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFH43506.1 - 0.22 10.8 0.5 0.46 9.8 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.25 KFH43507.1 - 9e-19 67.9 0.0 1.3e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43507.1 - 2e-06 27.3 0.0 0.02 14.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KFH43507.1 - 0.00047 19.6 0.0 0.66 9.2 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KFH43507.1 - 0.044 13.7 0.0 0.09 12.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KFH43508.1 - 3.7e-52 177.2 0.0 4.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43508.1 - 4.2e-33 114.5 0.0 5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH43508.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH43508.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KFH43509.1 - 4.8e-33 114.6 46.9 1.8e-21 76.5 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43509.1 - 3.1e-11 42.8 28.9 8.1e-06 24.9 9.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KFH43509.1 - 8.3e-09 34.5 3.7 8.3e-09 34.5 3.7 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KFH43509.1 - 0.005 15.7 13.9 0.006 15.5 0.3 2.4 2 1 0 2 2 2 2 MFS_1 like family Shal-type PF11601.8 KFH43509.1 - 0.21 11.1 1.6 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal Acyltransferase PF01553.21 KFH43511.1 - 2.4e-17 62.8 0.0 4.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF559 PF04480.12 KFH43511.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) DUF1308 PF07000.11 KFH43512.1 - 4.7e-07 29.9 0.0 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF3416 PF11896.8 KFH43512.1 - 0.03 14.6 0.8 0.071 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) GYF PF02213.16 KFH43513.1 - 2.9e-17 62.0 0.2 5.7e-17 61.1 0.2 1.5 1 0 0 1 1 1 1 GYF domain AA_permease PF00324.21 KFH43514.1 - 7.1e-94 315.1 34.8 8.6e-94 314.8 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH43514.1 - 3.3e-23 82.2 39.8 4e-23 81.9 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4389 PF14333.6 KFH43514.1 - 8.5 6.4 8.6 4.4 7.3 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) GMC_oxred_N PF00732.19 KFH43515.1 - 4.1e-30 105.2 0.0 8.8e-17 61.4 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH43515.1 - 7.4e-27 94.6 0.0 1.4e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFH43515.1 - 9.5e-05 22.6 1.1 0.00026 21.1 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH43515.1 - 0.0021 17.3 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFH43515.1 - 0.0058 16.3 0.3 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KFH43515.1 - 0.031 13.5 0.0 7.2 5.8 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH43515.1 - 0.032 13.3 0.5 0.053 12.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KFH43515.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KFH43515.1 - 0.11 12.0 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH43515.1 - 0.21 10.2 0.1 0.32 9.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Macro PF01661.21 KFH43517.1 - 7.3e-40 135.7 0.0 1.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Macro domain MMS1_N PF10433.9 KFH43518.1 - 3.4e-117 392.1 0.0 6e-117 391.3 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFH43518.1 - 1.3e-57 195.6 0.0 5.7e-57 193.5 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region tRNA-synt_1c PF00749.21 KFH43521.1 - 3.4e-101 338.3 0.0 3.4e-101 338.3 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFH43521.1 - 2e-31 109.2 0.0 5.1e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WD40 PF00400.32 KFH43522.1 - 6.6e-13 48.9 3.4 0.099 13.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43522.1 - 0.00054 20.2 0.4 0.47 10.8 0.1 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KFH43523.1 - 1.4e-13 51.4 0.0 1.2e-10 41.8 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH43523.1 - 5.3e-07 30.1 0.0 0.00014 22.2 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH43523.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Exo_endo_phos PF03372.23 KFH43525.1 - 9.4e-07 28.6 2.6 2e-06 27.5 2.6 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFH43525.1 - 0.12 12.2 0.2 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase ketoacyl-synt PF00109.26 KFH43527.1 - 2.9e-84 282.6 0.0 6.5e-84 281.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFH43527.1 - 2.6e-65 221.0 0.8 5.1e-65 220.1 0.8 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH43527.1 - 4.2e-60 202.7 0.2 2.7e-59 200.1 0.0 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KFH43527.1 - 1.7e-42 144.1 0.6 5.3e-42 142.6 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFH43527.1 - 3e-15 56.3 0.0 5.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFH43527.1 - 3.8e-15 56.3 0.0 8.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KFH43527.1 - 3.3e-14 53.0 0.0 8e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KFH43527.1 - 5.2e-08 32.6 0.1 2.1e-06 27.3 0.0 3.3 3 1 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KFH43527.1 - 5.7e-06 25.9 0.8 1.3e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KFH43527.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ProRS-C_1 PF09180.11 KFH43528.1 - 3.3e-23 81.7 0.3 9.2e-23 80.2 0.3 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KFH43528.1 - 2e-21 76.8 0.0 3.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFH43528.1 - 4.5e-18 65.2 0.2 1.3e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Glyco_hydro_61 PF03443.14 KFH43529.1 - 4e-59 200.0 0.0 4.7e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rieske PF00355.26 KFH43530.1 - 2.9e-11 43.1 0.0 4.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KFH43530.1 - 3.3e-10 40.3 0.2 1e-09 38.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region WD40 PF00400.32 KFH43531.1 - 3.8 8.5 14.5 93 4.1 0.3 5.7 5 1 0 5 5 5 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 KFH43532.1 - 1.4e-153 512.1 10.2 1.6e-153 511.9 10.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peroxidase_2 PF01328.17 KFH43533.1 - 6.5e-33 114.8 0.0 1.9e-31 110.1 0.0 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 Pantoate_ligase PF02569.15 KFH43534.1 - 4.3e-91 304.8 0.0 5.2e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ion_trans PF00520.31 KFH43535.1 - 3.8e-07 29.6 23.7 1.6e-06 27.6 23.7 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFH43535.1 - 8.2e-05 21.5 11.5 0.018 13.7 4.0 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF872 PF05915.12 KFH43535.1 - 0.049 13.8 0.9 2.9 8.1 1.3 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FlxA PF14282.6 KFH43535.1 - 0.05 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 FlxA-like protein PQ-loop PF04193.14 KFH43536.1 - 7.2e-20 70.5 16.1 2e-11 43.4 1.9 3.1 3 1 0 3 3 3 2 PQ loop repeat YiiD_C PF09500.10 KFH43536.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) MtN3_slv PF03083.16 KFH43536.1 - 0.13 12.3 3.6 0.71 10.0 0.1 2.9 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange UPF0086 PF01868.16 KFH43537.1 - 2.6e-29 101.0 0.1 3.8e-29 100.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SAGA-Tad1 PF12767.7 KFH43537.1 - 0.075 12.8 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AMP-binding PF00501.28 KFH43538.1 - 9.6e-66 222.1 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH43538.1 - 2.1e-12 47.9 1.4 3.4e-12 47.2 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TPR_2 PF07719.17 KFH43539.1 - 2.9e-09 36.3 6.9 0.0084 16.2 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH43539.1 - 4.6e-09 35.7 0.7 0.015 15.1 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFH43539.1 - 6.3e-09 36.3 0.3 6.3e-09 36.3 0.3 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFH43539.1 - 7.3e-07 28.8 0.1 0.0016 18.1 0.0 4.2 4 1 1 5 5 5 1 TPR repeat TPR_8 PF13181.6 KFH43539.1 - 3e-06 27.0 0.1 0.18 12.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH43539.1 - 5.5e-06 26.8 5.3 0.0086 16.6 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH43539.1 - 1.2e-05 25.5 12.4 0.014 15.7 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43539.1 - 0.00014 22.4 1.4 0.004 17.9 0.5 6.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43539.1 - 0.0014 18.5 7.9 0.51 10.5 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFH43539.1 - 0.0089 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_17 PF13431.6 KFH43539.1 - 0.088 13.2 0.0 5.8 7.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFH43539.1 - 0.44 10.5 2.8 4.6 7.2 0.7 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CFEM PF05730.11 KFH43540.1 - 5.2e-13 48.9 10.8 8.4e-13 48.2 10.8 1.3 1 0 0 1 1 1 1 CFEM domain PKD_channel PF08016.12 KFH43541.1 - 1.6e-05 23.8 17.8 0.00021 20.1 17.8 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFH43541.1 - 5.3e-05 22.6 27.2 0.0005 19.4 27.2 2.1 1 1 0 1 1 1 1 Ion transport protein COX2-transmemb PF09125.10 KFH43541.1 - 0.25 11.2 1.8 1 9.2 1.8 2.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DUF4212 PF13937.6 KFH43541.1 - 0.28 11.6 10.0 1.1 9.7 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) T_hemolysin PF12261.8 KFH43542.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 1 1 2 2 2 0 Thermostable hemolysin Cyt-b5 PF00173.28 KFH43543.1 - 2.3e-15 56.5 0.4 9.1e-07 28.9 0.0 3.4 3 0 0 3 3 3 3 Cytochrome b5-like Heme/Steroid binding domain Cellulase PF00150.18 KFH43545.1 - 2.9e-11 43.3 0.2 2.3e-07 30.6 0.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 KFH43546.1 - 6e-41 140.5 54.0 6e-41 140.5 54.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH43546.1 - 4.5e-14 51.8 19.1 1.6e-13 50.0 19.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH43546.1 - 1.1e-05 24.5 12.8 1.1e-05 24.5 12.8 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter Renin_r PF07850.14 KFH43546.1 - 0.032 14.8 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 Renin receptor-like protein TPR_21 PF09976.9 KFH43546.1 - 0.5 10.0 1.3 0.91 9.2 1.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain RRM_3 PF08777.11 KFH43547.1 - 3.2 7.8 5.5 0.78 9.8 0.3 2.3 2 1 1 3 3 3 0 RNA binding motif ABC_tran PF00005.27 KFH43548.1 - 2.8e-47 160.7 0.1 8.2e-24 84.7 0.0 3.5 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KFH43548.1 - 2.8e-29 101.0 0.2 1.7e-28 98.5 0.0 2.5 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 KFH43548.1 - 1.7e-18 67.5 0.0 0.002 18.0 0.0 5.0 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFH43548.1 - 2.7e-16 59.7 0.2 2.1e-05 24.1 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH43548.1 - 6.3e-09 35.4 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH43548.1 - 1.9e-08 35.1 10.3 0.0001 22.9 0.4 3.1 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KFH43548.1 - 5.3e-08 33.0 0.0 0.00069 19.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFH43548.1 - 1e-07 32.3 0.0 0.0052 17.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KFH43548.1 - 3.1e-07 30.5 0.0 0.0025 17.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KFH43548.1 - 1.4e-06 28.7 0.1 0.025 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFH43548.1 - 2.6e-06 27.4 0.1 0.064 13.0 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 KFH43548.1 - 2.8e-06 27.9 0.2 0.17 12.5 0.0 4.0 4 0 0 4 4 3 2 AAA domain Dynamin_N PF00350.23 KFH43548.1 - 6.4e-06 26.3 0.1 0.0012 18.9 0.0 3.1 3 1 0 3 3 2 1 Dynamin family AAA PF00004.29 KFH43548.1 - 1.3e-05 25.6 0.0 0.27 11.6 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH43548.1 - 3.6e-05 24.2 0.0 0.33 11.3 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 KFH43548.1 - 4.6e-05 22.5 0.1 0.28 10.1 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KFH43548.1 - 5.9e-05 22.8 0.1 0.066 13.0 0.0 3.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KFH43548.1 - 6.5e-05 23.1 0.0 0.53 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFH43548.1 - 9.1e-05 22.8 0.0 0.79 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KFH43548.1 - 0.00018 21.1 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KFH43548.1 - 0.00036 19.8 0.0 1.1 8.4 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit NACHT PF05729.12 KFH43548.1 - 0.00055 19.9 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain HEAT PF02985.22 KFH43548.1 - 0.00062 19.8 0.7 10 6.7 0.1 4.4 4 0 0 4 4 3 0 HEAT repeat AAA_24 PF13479.6 KFH43548.1 - 0.00077 19.2 0.1 1.5 8.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFH43548.1 - 0.0011 19.0 0.1 3.6 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KFH43548.1 - 0.0013 18.9 0.0 0.98 9.5 0.0 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain Rad17 PF03215.15 KFH43548.1 - 0.0014 18.5 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFH43548.1 - 0.0015 18.3 0.0 3 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KFH43548.1 - 0.0041 16.7 0.0 4 7.0 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KFH43548.1 - 0.0045 16.3 0.5 2 7.6 0.0 2.9 3 0 0 3 3 3 1 Septin NB-ARC PF00931.22 KFH43548.1 - 0.0055 15.9 0.0 0.33 10.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 KFH43548.1 - 0.0066 16.7 0.0 1.7 8.9 0.0 3.4 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KFH43548.1 - 0.007 16.1 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 KFH43548.1 - 0.0082 16.1 0.0 2.8 7.8 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KFH43548.1 - 0.0091 15.8 0.0 7.2 6.3 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KFH43548.1 - 0.0099 16.1 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KFH43548.1 - 0.015 14.8 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region CLASP_N PF12348.8 KFH43548.1 - 0.019 14.5 0.0 0.092 12.3 0.0 2.1 1 1 1 2 2 2 0 CLASP N terminal IstB_IS21 PF01695.17 KFH43548.1 - 0.019 14.7 0.0 5.6 6.7 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein CLP1_P PF16575.5 KFH43548.1 - 0.021 14.7 0.7 0.8 9.5 0.0 2.7 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dopey_N PF04118.14 KFH43548.1 - 0.024 13.7 0.0 0.17 11.0 0.0 2.2 1 1 1 2 2 2 0 Dopey, N-terminal ATP-synt_ab PF00006.25 KFH43548.1 - 0.028 14.1 0.0 8.2 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 KFH43548.1 - 0.033 14.1 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_13 PF13166.6 KFH43548.1 - 0.048 12.3 3.7 2.4 6.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 KFH43548.1 - 0.054 12.5 0.1 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein HEAT_2 PF13646.6 KFH43548.1 - 0.06 13.7 3.9 1.6 9.2 2.5 3.1 2 1 1 3 3 3 0 HEAT repeats NTPase_1 PF03266.15 KFH43548.1 - 0.061 13.2 0.1 16 5.4 0.0 2.8 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KFH43548.1 - 0.062 13.0 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 KFH43548.1 - 0.066 12.6 0.0 4.4 6.6 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFH43548.1 - 0.066 12.8 0.0 6.6 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFH43548.1 - 0.067 12.5 0.0 12 5.1 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin Transglut_prok PF09017.10 KFH43548.1 - 0.071 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Microbial transglutaminase TsaE PF02367.17 KFH43548.1 - 0.084 12.9 0.2 50 3.9 0.0 3.4 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1889 PF08986.10 KFH43548.1 - 0.086 13.2 0.0 0.88 10.0 0.0 2.7 2 0 0 2 2 1 0 Domain of unknown function (DUF1889) MukB PF04310.12 KFH43548.1 - 0.091 12.6 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF815 PF05673.13 KFH43548.1 - 0.1 11.8 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HEAT_EZ PF13513.6 KFH43548.1 - 0.14 12.7 5.4 4.5 7.9 0.0 4.8 5 1 1 6 6 3 0 HEAT-like repeat FeoB_N PF02421.18 KFH43548.1 - 0.17 11.4 0.2 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ApbA PF02558.16 KFH43549.1 - 3.8e-26 91.5 0.0 5.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KFH43549.1 - 4.2e-22 78.7 0.0 6.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Myb_DNA-bind_6 PF13921.6 KFH43550.1 - 0.00037 20.7 0.1 0.00086 19.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFH43550.1 - 0.037 14.2 0.1 0.077 13.2 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain OPT PF03169.15 KFH43551.1 - 2.9e-187 624.1 51.4 3.3e-187 623.9 51.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosomal_S4e PF00900.20 KFH43552.1 - 6.3e-37 125.3 0.1 1.5e-36 124.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFH43552.1 - 2.2e-24 84.8 0.0 3.9e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KFH43552.1 - 8.5e-18 64.2 3.3 1.6e-17 63.3 3.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KFH43552.1 - 1.7e-05 24.4 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFH43552.1 - 0.0006 19.7 1.2 0.0006 19.7 1.2 3.2 4 0 0 4 4 4 1 KOW motif Sipho_tail PF05709.11 KFH43552.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Phage tail protein SH3_18 PF18354.1 KFH43552.1 - 0.12 12.4 0.1 2.8 8.1 0.0 2.5 3 0 0 3 3 3 0 CarS bacterial SH3 domain ADH_zinc_N PF00107.26 KFH43553.1 - 1.3e-25 89.8 0.5 2e-25 89.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH43553.1 - 2.5e-15 56.3 0.8 5.5e-15 55.2 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KFH43553.1 - 9.4e-06 25.1 0.2 1.7e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KFH43553.1 - 2.5e-05 24.5 0.1 4.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KFH43553.1 - 0.00017 20.9 0.1 0.00025 20.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFH43553.1 - 0.0012 18.2 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.20 KFH43553.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase ELFV_dehydrog PF00208.21 KFH43553.1 - 0.003 17.3 0.2 0.0047 16.7 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_11 PF08241.12 KFH43553.1 - 0.0036 17.9 0.3 0.011 16.3 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43553.1 - 0.004 17.8 0.1 0.0081 16.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KFH43553.1 - 0.0092 15.9 0.6 0.015 15.2 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cellsynth_D PF03500.13 KFH43553.1 - 0.033 14.1 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Cellulose synthase subunit D Methyltransf_31 PF13847.6 KFH43553.1 - 0.055 13.3 0.0 1.1 9.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 KFH43553.1 - 0.13 12.9 2.1 0.2 12.3 0.4 2.1 1 1 0 2 2 2 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 KFH43553.1 - 0.15 11.6 0.4 0.32 10.6 0.2 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RdRP PF05183.12 KFH43554.1 - 6.8e-183 609.5 0.0 8.8e-183 609.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase SnoaL PF07366.12 KFH43556.1 - 0.00021 21.1 0.0 0.00026 20.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase EthD PF07110.11 KFH43557.1 - 2.2e-18 67.2 2.1 3e-18 66.7 2.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFH43557.1 - 6.1e-09 36.3 0.1 8.3e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Raptor_N PF14538.6 KFH43558.1 - 8.9e-65 217.1 0.0 1.6e-64 216.3 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KFH43558.1 - 2.1e-06 28.3 2.4 5.5 8.0 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFH43558.1 - 3.1e-05 24.0 0.1 0.28 11.3 0.0 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 KFH43558.1 - 0.0052 16.8 0.2 0.0098 15.9 0.2 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KFH43558.1 - 0.011 15.9 0.2 10 6.7 0.0 4.6 6 0 0 6 6 6 0 HEAT repeat Nup160 PF11715.8 KFH43558.1 - 0.022 13.4 0.1 0.054 12.1 0.1 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HEAT_2 PF13646.6 KFH43558.1 - 0.074 13.4 0.2 6.2 7.3 0.0 3.6 3 1 2 5 5 5 0 HEAT repeats CDP-OH_P_transf PF01066.21 KFH43559.1 - 3.3e-17 63.0 0.1 3.3e-17 63.0 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAD-oxidase_C PF02913.19 KFH43560.1 - 9.8e-62 208.8 0.6 7.4e-61 205.9 0.0 2.2 2 1 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFH43560.1 - 6.5e-34 116.7 0.0 1.3e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KFH43560.1 - 0.019 13.7 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SUR7 PF06687.12 KFH43561.1 - 1.7e-11 44.2 15.6 2.1e-11 43.9 15.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family MSP1a PF11670.8 KFH43561.1 - 0.078 12.3 0.6 0.15 11.3 0.6 1.6 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Peptidase_U4 PF03419.13 KFH43561.1 - 0.41 9.9 6.2 0.59 9.4 6.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Pox_P21 PF05313.12 KFH43561.1 - 2.2 7.8 9.8 3.8 7.0 9.8 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF2157 PF09925.9 KFH43561.1 - 2.7 7.8 6.8 4.6 7.0 6.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) MARVEL PF01284.23 KFH43561.1 - 3.4 7.7 13.0 9 6.3 13.3 1.4 1 1 0 1 1 1 0 Membrane-associating domain ABC1 PF03109.16 KFH43562.1 - 2.3e-18 66.5 0.0 4.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Nse4_C PF08743.10 KFH43562.1 - 0.073 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Nse4 C-terminal ELP6 PF09807.9 KFH43563.1 - 7.6e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KFH43563.1 - 0.081 12.3 0.0 0.15 11.3 0.0 1.3 1 1 0 1 1 1 0 KaiC Thioredoxin PF00085.20 KFH43564.1 - 2e-08 34.1 0.0 2.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFH43564.1 - 2.5e-05 24.5 0.0 0.21 12.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFH43564.1 - 0.0025 18.2 0.0 0.015 15.8 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFH43564.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF953 PF06110.11 KFH43564.1 - 0.019 14.6 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 KFH43564.1 - 0.03 14.5 0.1 0.056 13.6 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KFH43564.1 - 0.047 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin OST3_OST6 PF04756.13 KFH43564.1 - 0.2 11.0 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family NAC PF01849.18 KFH43567.1 - 4.5e-23 81.0 1.6 4.6e-23 81.0 0.1 1.8 2 0 0 2 2 2 1 NAC domain Ribosomal_L24e PF01246.20 KFH43568.1 - 2.1e-28 98.3 0.2 2.1e-28 98.3 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Glyco_hydro_25 PF01183.20 KFH43569.1 - 1e-43 149.6 1.5 1.2e-43 149.4 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Myb_DNA-binding PF00249.31 KFH43570.1 - 4.4e-17 62.0 0.5 2.2e-09 37.3 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH43570.1 - 5.1e-12 45.8 0.1 9.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KFH43570.1 - 4.4e-07 29.9 0.4 0.041 13.9 0.1 2.5 2 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KFH43570.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SMC_N PF02463.19 KFH43571.1 - 4e-26 91.8 0.0 6.7e-26 91.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH43571.1 - 1.6e-14 54.9 47.6 2.1e-12 48.0 17.6 5.2 3 2 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KFH43571.1 - 1.6e-06 28.1 11.8 0.00014 21.8 0.0 3.6 2 2 0 2 2 2 1 AAA ATPase domain Baculo_PEP_C PF04513.12 KFH43571.1 - 0.00025 21.1 11.8 1.3 9.0 0.1 5.2 4 1 1 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_21 PF13304.6 KFH43571.1 - 0.00026 20.9 14.2 0.0096 15.8 0.0 4.0 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system OmpH PF03938.14 KFH43571.1 - 0.0088 16.4 2.8 0.0088 16.4 2.8 5.9 2 2 3 5 5 5 2 Outer membrane protein (OmpH-like) AAA_29 PF13555.6 KFH43571.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BLOC1_2 PF10046.9 KFH43571.1 - 0.044 14.1 0.6 0.044 14.1 0.6 6.4 6 1 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RsgA_GTPase PF03193.16 KFH43571.1 - 0.087 12.7 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Spc7 PF08317.11 KFH43571.1 - 0.17 10.7 78.1 0.32 9.8 18.2 5.1 2 2 3 5 5 5 0 Spc7 kinetochore protein TLE_N PF03920.15 KFH43571.1 - 1.4 9.0 6.7 0.55 10.3 0.3 3.2 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF948 PF06103.11 KFH43571.1 - 2.1 8.7 18.8 17 5.7 1.3 6.0 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 KFH43571.1 - 4.2 7.2 14.7 1.5 8.6 0.9 4.0 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 KFH43571.1 - 7.9 7.0 14.3 13 6.4 0.2 6.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Ribosomal_L37e PF01907.19 KFH43572.1 - 4.7e-27 93.9 11.4 7.1e-27 93.3 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e zf-C4pol PF14260.6 KFH43572.1 - 0.02 15.3 0.7 0.032 14.7 0.7 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 KFH43572.1 - 0.031 14.3 1.5 0.049 13.7 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 KFH43572.1 - 0.33 10.8 4.3 0.54 10.2 4.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 KFH43572.1 - 1.8 7.9 5.2 1.1 8.7 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Cyclin PF08613.11 KFH43573.1 - 2.7e-06 27.8 3.7 2.7e-06 27.8 3.7 2.8 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KFH43573.1 - 0.00066 19.4 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KFH43574.1 - 2.1e-07 31.7 0.0 6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_4 PF13418.6 KFH43575.1 - 1.2e-30 105.3 7.4 3.2e-05 23.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFH43575.1 - 2.1e-29 101.2 6.6 8.1e-06 26.0 0.3 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFH43575.1 - 3.2e-29 100.4 4.4 5e-07 29.6 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFH43575.1 - 1.3e-27 95.2 3.5 6.3e-07 29.5 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KFH43575.1 - 1.3e-27 95.1 1.3 2e-10 40.1 0.4 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFH43575.1 - 3.8e-21 74.2 7.1 8.8e-07 28.7 0.3 6.4 6 0 0 6 6 6 5 Kelch motif Tropomyosin_1 PF12718.7 KFH43575.1 - 0.0069 16.5 16.9 0.0069 16.5 16.9 7.2 3 2 4 7 7 6 2 Tropomyosin like ZapB PF06005.12 KFH43575.1 - 0.0087 16.5 12.3 0.0087 16.5 12.3 10.2 5 4 4 9 9 6 1 Cell division protein ZapB Uso1_p115_C PF04871.13 KFH43575.1 - 0.0098 16.3 9.9 0.0098 16.3 9.9 7.8 3 2 4 8 8 8 1 Uso1 / p115 like vesicle tethering protein, C terminal region Pox_A_type_inc PF04508.12 KFH43575.1 - 0.2 11.6 8.1 5.7 7.0 0.0 4.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 KFH43575.1 - 4.6 7.3 49.6 0.016 15.2 4.7 7.0 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KFH43575.1 - 6.4 5.5 89.3 0.029 13.3 47.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DEAD PF00270.29 KFH43576.1 - 2.3e-38 131.7 0.0 3.9e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH43576.1 - 7.1e-26 90.7 0.1 6.4e-24 84.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH43576.1 - 3.4e-08 33.7 0.0 8.3e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KFH43576.1 - 0.058 13.9 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) PAP1 PF08601.10 KFH43577.1 - 1e-07 32.1 12.0 2.7e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KFH43577.1 - 1.4e-07 31.4 16.6 3e-07 30.4 16.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Protocadherin PF08374.11 KFH43577.1 - 0.0045 17.0 2.0 0.0075 16.3 2.0 1.3 1 0 0 1 1 1 1 Protocadherin SHE3 PF17078.5 KFH43577.1 - 0.0086 15.8 5.8 0.013 15.3 5.8 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 KFH43577.1 - 0.009 14.0 1.5 0.011 13.7 1.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 KFH43577.1 - 0.029 14.9 10.3 0.047 14.2 10.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor ADIP PF11559.8 KFH43577.1 - 0.046 13.8 10.4 0.071 13.2 10.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5101 PF17031.5 KFH43577.1 - 0.072 13.2 2.4 0.16 12.1 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) GIT_CC PF16559.5 KFH43577.1 - 0.17 11.8 1.8 0.3 11.0 1.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 KFH43577.1 - 0.23 11.9 2.1 0.38 11.2 2.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KFH43577.1 - 1.6 8.8 6.6 2.4 8.2 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GvpL_GvpF PF06386.11 KFH43577.1 - 1.8 8.5 6.4 2.9 7.8 6.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF M PF02370.16 KFH43577.1 - 2.7 8.8 8.7 2.2 9.1 3.1 3.0 1 1 0 2 2 2 0 M protein repeat bZIP_2 PF07716.15 KFH43577.1 - 4.8 7.4 19.4 26 5.0 19.4 2.0 1 1 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.6 KFH43577.1 - 6.6 6.0 7.6 9.2 5.5 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acyl-CoA_dh_1 PF00441.24 KFH43579.1 - 1.1e-33 116.6 0.1 1.7e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH43579.1 - 1.7e-23 82.6 0.2 3e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFH43579.1 - 4.6e-12 46.6 1.8 3.3e-11 43.8 0.1 2.9 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH43579.1 - 4.8e-06 26.9 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Rpr2 PF04032.16 KFH43580.1 - 1.6e-25 89.2 0.3 2.6e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain N-SET PF11764.8 KFH43580.1 - 1.4 9.0 6.2 0.17 12.0 1.5 1.7 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N MFS_1 PF07690.16 KFH43581.1 - 1.5e-35 122.8 26.4 1.2e-26 93.5 6.2 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43581.1 - 1.2e-09 37.6 8.5 1.2e-09 37.6 8.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFH43581.1 - 0.0003 19.3 1.4 0.00059 18.4 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) eIF_4EBP PF05456.11 KFH43581.1 - 0.11 12.5 1.1 0.33 10.9 1.1 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Septin PF00735.18 KFH43582.1 - 1.6e-30 106.4 0.2 3.4e-11 43.0 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 KFH43582.1 - 0.0076 16.3 0.1 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH43582.1 - 0.016 14.7 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KFH43582.1 - 0.017 15.7 3.9 0.065 13.7 3.9 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFH43582.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KFH43582.1 - 0.08 13.0 0.2 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Repressor_Mnt PF11423.8 KFH43582.1 - 0.13 12.0 1.2 0.3 10.9 1.2 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt FtsK_SpoIIIE PF01580.18 KFH43582.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Fumble PF03630.14 KFH43583.1 - 2.1e-145 484.0 0.0 2.6e-145 483.7 0.0 1.1 1 0 0 1 1 1 1 Fumble PT PF04886.12 KFH43583.1 - 0.062 12.9 4.7 0.13 11.8 4.7 1.5 1 0 0 1 1 1 0 PT repeat Sel1 PF08238.12 KFH43584.1 - 1e-46 156.3 21.5 3.1e-08 34.0 0.0 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 KFH43584.1 - 0.0021 18.3 0.1 1.4 9.5 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFH43584.1 - 0.086 13.2 0.7 0.45 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43584.1 - 0.19 12.6 10.5 2.6 9.1 0.2 5.4 4 2 1 5 5 5 0 Tetratricopeptide repeat CBP4 PF07960.11 KFH43585.1 - 1.3e-26 93.0 0.4 1.6e-26 92.7 0.4 1.1 1 0 0 1 1 1 1 CBP4 DASH_Hsk3 PF08227.11 KFH43586.1 - 5.6e-21 74.6 5.2 7.2e-21 74.3 5.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like LPP PF04728.13 KFH43586.1 - 0.12 12.8 1.0 0.19 12.2 1.0 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper A_deamin PF02137.18 KFH43587.1 - 1.7e-28 100.0 0.0 3e-28 99.2 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain TRI12 PF06609.13 KFH43588.1 - 1.8e-45 155.5 14.7 2.2e-45 155.2 14.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH43588.1 - 7.4e-19 67.9 38.0 7.4e-19 67.9 38.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43588.1 - 3.3e-06 26.2 13.9 3.3e-06 26.2 13.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter NACHT_N PF17100.5 KFH43588.1 - 0.078 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Peptidase_M24 PF00557.24 KFH43589.1 - 4.4e-43 147.4 0.0 5.8e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Band_7 PF01145.25 KFH43590.1 - 1.1e-23 84.1 3.6 1.7e-23 83.6 3.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PrmA PF06325.13 KFH43591.1 - 3e-10 40.0 0.0 4.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFH43591.1 - 3.3e-10 40.5 0.0 7.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH43591.1 - 6.7e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH43591.1 - 1.9e-06 28.5 0.0 4.6e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFH43591.1 - 2.2e-06 26.8 0.1 3.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KFH43591.1 - 5.8e-05 23.1 0.2 0.00013 22.0 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH43591.1 - 6.2e-05 22.9 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFH43591.1 - 0.00067 19.0 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFH43591.1 - 0.002 17.7 0.1 0.0034 16.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFH43591.1 - 0.0032 18.2 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFH43591.1 - 0.0098 15.8 0.1 0.017 15.0 0.1 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFH43591.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 KFH43591.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFH43591.1 - 0.058 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 KFH43591.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPT PF03151.16 KFH43592.1 - 6.6e-21 74.9 11.6 9.6e-21 74.4 11.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH43592.1 - 3.5e-05 24.0 32.3 0.00036 20.7 1.9 2.7 3 1 0 3 3 3 2 EamA-like transporter family Ribosomal_S6e PF01092.19 KFH43592.1 - 0.038 14.0 0.6 0.13 12.2 0.0 2.1 3 0 0 3 3 3 0 Ribosomal protein S6e PUNUT PF16913.5 KFH43592.1 - 0.13 11.5 16.2 1.2 8.2 16.1 2.3 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport UAA PF08449.11 KFH43592.1 - 0.27 10.4 20.8 0.035 13.3 16.4 1.7 2 1 0 2 2 2 0 UAA transporter family PBP1_TM PF14812.6 KFH43592.1 - 2.3 8.7 11.1 0.59 10.5 4.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ELH PF02323.15 KFH43593.1 - 0.14 11.5 1.0 0.16 11.3 1.0 1.0 1 0 0 1 1 1 0 Egg-laying hormone precursor HLH PF00010.26 KFH43594.1 - 5.7e-13 48.6 0.6 1.1e-12 47.7 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUI1 PF01253.22 KFH43596.1 - 2.8e-21 75.8 0.4 8e-21 74.4 0.4 1.8 1 1 0 1 1 1 1 Translation initiation factor SUI1 MscS_TM PF12794.7 KFH43596.1 - 1.3 7.8 2.4 1.6 7.5 2.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 KFH43597.1 - 1.6e-45 155.6 0.0 2.4e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43597.1 - 2.7e-18 66.2 0.0 4.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH43597.1 - 0.00027 20.9 0.7 0.77 9.6 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFH43597.1 - 0.16 11.6 0.1 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family DUF1765 PF08578.10 KFH43598.1 - 1e-44 152.0 4.8 1.9e-44 151.1 4.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) DUF5562 PF17717.1 KFH43599.1 - 0.072 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5562) EphA2_TM PF14575.6 KFH43599.1 - 0.073 14.0 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 KFH43599.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 KFH43599.1 - 0.17 11.8 2.6 0.81 9.6 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family Pap_E4 PF02711.14 KFH43599.1 - 5.2 8.1 10.9 0.57 11.2 5.4 2.2 2 0 0 2 2 2 0 E4 protein Fungal_trans_2 PF11951.8 KFH43600.1 - 1.6e-05 24.0 0.0 3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43600.1 - 0.017 15.2 7.9 0.017 15.2 7.9 2.5 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT PF03061.22 KFH43601.1 - 5.9e-07 29.8 0.0 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily ACP_PD PF04336.12 KFH43601.1 - 0.074 13.5 1.3 0.46 10.9 0.4 2.5 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase VWA_2 PF13519.6 KFH43602.1 - 5.9e-27 94.4 0.3 1.6e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFH43602.1 - 8.9e-12 45.6 0.2 1.2e-11 45.2 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KFH43602.1 - 9.2e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KFH43602.1 - 0.008 16.0 1.4 0.036 14.0 1.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF243 PF03103.17 KFH43602.1 - 0.029 14.7 0.4 0.029 14.7 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Dynein_heavy PF03028.15 KFH43602.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain HNOBA PF07701.14 KFH43602.1 - 0.24 10.8 1.8 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Heme NO binding associated ERCC4 PF02732.15 KFH43603.1 - 9e-25 87.7 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 KFH43603.1 - 0.0019 18.8 0.0 0.0085 16.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_8 PF14716.6 KFH43603.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Peptidase_M15_3 PF08291.11 KFH43604.1 - 6.9e-30 103.4 0.1 9.7e-30 102.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase M15 PG_binding_1 PF01471.18 KFH43604.1 - 4.4e-14 52.4 0.2 7e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M15_2 PF05951.13 KFH43604.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Extensin-like_C PF06904.12 KFH43604.1 - 0.047 13.7 1.6 3.4 7.7 0.8 2.2 1 1 1 2 2 2 0 Extensin-like protein C-terminus Lum_binding PF00677.17 KFH43605.1 - 2.1e-45 152.6 0.7 5.5e-22 77.5 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain Bromo_TP PF07524.13 KFH43606.1 - 3.1e-07 30.3 0.1 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 KFH43606.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HlyIII PF03006.20 KFH43607.1 - 3.7e-32 111.9 18.0 5.8e-32 111.2 18.0 1.3 1 1 0 1 1 1 1 Haemolysin-III related DUF4149 PF13664.6 KFH43607.1 - 0.017 15.4 2.0 0.047 14.0 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) RWD PF05773.22 KFH43608.1 - 1.1e-25 90.1 0.4 1.9e-25 89.4 0.4 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KFH43608.1 - 2.8e-05 24.5 8.5 3.8e-05 24.1 7.4 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 UQ_con PF00179.26 KFH43608.1 - 0.0041 16.8 0.4 0.0066 16.1 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2852 PF11014.8 KFH43608.1 - 0.06 13.5 2.5 0.09 12.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) UNC-79 PF14776.6 KFH43608.1 - 0.18 10.5 1.1 0.23 10.2 1.1 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 RTC_insert PF05189.13 KFH43609.1 - 3.1e-29 101.5 0.1 6.1e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KFH43609.1 - 1e-28 100.1 0.2 1.3e-28 99.8 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase G-patch PF01585.23 KFH43610.1 - 3e-05 23.8 0.0 8.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 G-patch domain SDA1 PF05285.12 KFH43610.1 - 0.0018 17.7 23.3 0.0018 17.7 23.3 2.1 1 1 1 2 2 2 1 SDA1 AF-4 PF05110.13 KFH43610.1 - 0.022 12.9 44.9 0.027 12.6 44.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mitofilin PF09731.9 KFH43610.1 - 0.3 9.9 37.0 0.37 9.6 37.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.10 KFH43610.1 - 0.31 10.4 52.8 0.47 9.8 52.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GREB1 PF15782.5 KFH43610.1 - 1.1 6.2 28.0 1.4 6.0 28.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF936 PF06075.12 KFH43610.1 - 1.4 7.7 38.6 1.9 7.3 38.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF3439 PF11921.8 KFH43610.1 - 1.6 8.7 12.2 2.9 7.9 11.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S9 PF00326.21 KFH43611.1 - 4.2e-58 196.3 0.1 1.2e-57 194.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 KFH43611.1 - 0.00022 21.1 0.4 0.0029 17.5 0.0 3.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KFH43611.1 - 0.012 14.4 0.0 0.12 11.0 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KFH43611.1 - 0.079 12.8 0.0 0.98 9.2 0.0 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFH43611.1 - 0.087 12.0 0.0 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) SWI-SNF_Ssr4 PF08549.10 KFH43612.1 - 6.1e-269 894.6 3.5 7.2e-269 894.4 3.5 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) PhoD PF09423.10 KFH43613.1 - 5e-05 22.5 0.8 0.002 17.2 0.1 2.7 3 0 0 3 3 3 2 PhoD-like phosphatase DUF3546 PF12066.8 KFH43614.1 - 7.7e-28 96.9 6.3 7.7e-28 96.9 6.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KFH43614.1 - 8e-12 44.8 0.3 2e-11 43.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KFH43614.1 - 2.6e-10 41.0 11.7 4.1e-09 37.1 11.7 2.8 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Neur_chan_memb PF02932.16 KFH43614.1 - 0.39 10.7 1.4 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L21p PF00829.21 KFH43615.1 - 1.2e-12 47.9 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein HAD PF12710.7 KFH43616.1 - 1.1e-15 58.5 0.5 3e-15 57.1 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF5005 PF16396.5 KFH43616.1 - 0.0011 17.8 0.2 0.0018 17.1 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5005) HAD_2 PF13419.6 KFH43616.1 - 0.0011 19.1 0.4 0.33 11.0 0.2 3.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_S8e PF01201.22 KFH43617.1 - 2.1e-42 144.6 0.1 4e-42 143.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KFH43617.1 - 1.1 8.6 6.5 5.2 6.4 6.5 1.9 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Elongin_A PF06881.11 KFH43618.1 - 3.4e-29 101.4 0.2 5.6e-29 100.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MOSC PF03473.17 KFH43619.1 - 3.4e-39 133.9 0.0 6.2e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFH43619.1 - 4.4e-22 78.2 0.0 8e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KFH43619.1 - 2.4e-15 56.4 0.0 1.4e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aldedh PF00171.22 KFH43620.1 - 2.2e-105 352.8 0.0 2.7e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 KFH43621.1 - 1.1e-18 66.8 0.0 1.8e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 KFH43621.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Cytotoxic Methyltransf_11 PF08241.12 KFH43622.1 - 3.3e-14 53.3 0.0 8.7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43622.1 - 5.1e-07 30.3 0.0 1.3e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH43622.1 - 0.0026 17.6 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH43622.1 - 0.0099 16.6 0.0 0.044 14.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH43622.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Per1 PF04080.13 KFH43623.1 - 5.6e-106 354.0 13.5 6.6e-106 353.7 13.5 1.0 1 0 0 1 1 1 1 Per1-like family DUF3522 PF12036.8 KFH43623.1 - 0.024 14.9 7.9 0.039 14.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Glyco_hydro_15 PF00723.21 KFH43624.1 - 6.6e-47 160.3 0.0 8.1e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CorA PF01544.18 KFH43625.1 - 0.0001 21.7 0.0 0.00072 19.0 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein RNA_pol_Rpb4 PF03874.16 KFH43626.1 - 2.2e-26 92.6 4.8 2.7e-26 92.3 4.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.6 KFH43626.1 - 0.022 14.9 0.1 0.053 13.7 0.1 1.6 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin GFA PF04828.14 KFH43627.1 - 7.7e-13 48.6 1.1 4.1e-06 27.0 0.4 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nbl1_Borealin_N PF10444.9 KFH43628.1 - 3.7e-19 68.1 6.7 7.5e-19 67.1 6.7 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Coleoptericin PF06286.11 KFH43628.1 - 6.1 7.0 7.4 0.42 10.7 0.5 2.4 1 1 0 2 2 2 0 Coleoptericin PGM_PMM_I PF02878.16 KFH43629.1 - 2.6e-17 62.8 0.0 5.1e-08 32.7 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFH43629.1 - 1.1e-12 48.0 0.2 5.3e-12 45.7 0.2 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFH43629.1 - 0.017 15.3 0.1 0.046 13.9 0.1 1.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFH43629.1 - 0.045 14.4 0.1 0.28 11.8 0.1 2.4 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF3632 PF12311.8 KFH43630.1 - 2.8e-13 50.7 0.1 1.2e-09 38.8 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3632) DUF2267 PF10025.9 KFH43630.1 - 0.071 13.4 0.0 0.88 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_12 PF13424.6 KFH43632.1 - 1.5e-15 57.2 0.5 3.2e-08 33.8 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFH43632.1 - 2.8e-14 53.5 0.3 5.5e-06 26.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH43632.1 - 1.7e-12 46.4 0.1 0.00028 20.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43632.1 - 1.7e-10 40.8 7.4 0.076 13.9 0.0 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFH43632.1 - 3.9e-10 40.1 1.9 0.0022 18.4 0.0 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH43632.1 - 5.1e-10 38.9 1.6 0.021 14.7 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43632.1 - 1.3e-09 37.4 1.2 0.0012 18.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH43632.1 - 1.7e-08 33.9 0.0 0.012 15.4 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH43632.1 - 8.9e-07 28.6 4.4 0.00063 19.2 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KFH43632.1 - 1.5e-06 28.0 0.0 0.0053 16.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFH43632.1 - 0.00022 21.6 4.1 2 9.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH43632.1 - 0.001 19.2 0.0 9.8 6.5 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 KFH43632.1 - 0.003 17.2 0.9 0.2 11.3 0.2 3.3 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 KFH43632.1 - 0.0049 16.5 0.0 16 5.3 0.0 4.0 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 KFH43632.1 - 0.0061 16.7 3.5 0.77 9.9 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PapC_C PF13953.6 KFH43632.1 - 0.021 14.7 0.2 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 PapC C-terminal domain TPR_17 PF13431.6 KFH43632.1 - 0.049 14.0 0.0 21 5.8 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KFH43632.1 - 0.46 9.4 2.0 4.6 6.1 0.3 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 KFH43632.1 - 3.4 8.6 12.1 3.2 8.6 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1746 PF08508.10 KFH43634.1 - 6.4e-31 107.1 0.6 8.3e-29 100.3 0.2 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1746) CPL PF08144.11 KFH43635.1 - 9.2e-36 123.3 0.0 3.2e-34 118.3 0.0 3.1 3 2 1 4 4 4 1 CPL (NUC119) domain PPR_2 PF13041.6 KFH43636.1 - 3.5e-09 36.7 2.0 7.4e-07 29.3 0.0 4.5 5 0 0 5 5 4 1 PPR repeat family PPR PF01535.20 KFH43636.1 - 0.00031 20.8 0.5 2 8.8 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_19 PF14559.6 KFH43636.1 - 0.0013 19.2 0.0 3.5 8.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.7 KFH43636.1 - 0.016 14.9 1.5 25 4.7 0.1 4.4 5 0 0 5 5 5 0 PPR repeat Exog_C PF18026.1 KFH43636.1 - 0.035 14.1 0.2 2.5 8.2 0.1 2.8 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain PPR_3 PF13812.6 KFH43636.1 - 0.036 14.2 0.0 0.91 9.6 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Peptidase_C92 PF05708.12 KFH43636.1 - 0.07 13.2 0.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Trep_dent_lipo PF09710.10 KFH43636.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) TPR_16 PF13432.6 KFH43636.1 - 0.11 13.2 0.3 16 6.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CesT PF05932.13 KFH43636.1 - 0.14 12.3 0.1 6.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family AEP1 PF17049.5 KFH43636.1 - 0.19 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 ATPase expression protein 1 TPR_6 PF13174.6 KFH43636.1 - 4.6 8.1 5.4 17 6.3 0.1 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF2949 PF11165.8 KFH43637.1 - 0.08 13.3 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2949) tRNA-synt_2d PF01409.20 KFH43638.1 - 4e-85 285.2 0.0 5.4e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KFH43638.1 - 3.4e-17 62.5 0.3 1e-16 60.9 0.3 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KFH43638.1 - 2.4e-07 30.4 0.0 0.0066 15.9 0.0 3.2 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KFH43638.1 - 7.1e-05 22.7 2.7 0.0002 21.3 2.7 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KFH43638.1 - 0.00013 21.1 0.1 0.0034 16.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1938 PF09153.10 KFH43638.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) 6PGD PF00393.19 KFH43639.1 - 2.8e-127 424.0 0.0 3.5e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFH43639.1 - 1.1e-49 168.6 0.0 1.8e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFH43639.1 - 0.13 12.5 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 KFH43639.1 - 0.24 11.3 0.2 15 5.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIF_beta_N PF17683.1 KFH43642.1 - 8.9e-31 107.4 0.0 8.9e-31 107.4 0.0 1.9 3 0 0 3 3 3 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KFH43642.1 - 3.2e-28 97.7 0.2 5.2e-28 97.0 0.2 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain CENP-B_dimeris PF09026.10 KFH43642.1 - 1.9 8.9 9.1 77 3.8 9.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GCV_H PF01597.19 KFH43643.1 - 2e-32 111.7 1.1 2.4e-32 111.4 1.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Pollen_allerg_1 PF01357.21 KFH43643.1 - 0.02 14.9 0.2 0.25 11.4 0.0 2.2 1 1 1 2 2 2 0 Pollen allergen PLDc_2 PF13091.6 KFH43644.1 - 5.8e-16 58.6 0.0 4.2e-09 36.4 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFH43644.1 - 8.6e-09 35.2 0.3 0.00016 21.7 0.0 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif FA PF08736.11 KFH43644.1 - 0.13 12.3 0.1 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 FERM adjacent (FA) CRAL_TRIO PF00650.20 KFH43645.1 - 3.3e-38 130.9 0.0 4.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH43645.1 - 1.9e-15 56.8 0.0 4.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFH43645.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PNTB PF02233.16 KFH43646.1 - 9.3e-173 575.4 23.7 9.3e-173 575.4 23.7 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KFH43646.1 - 4.4e-73 245.1 0.1 1.3e-72 243.5 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFH43646.1 - 2.4e-49 167.1 0.2 5.5e-49 165.9 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KFH43646.1 - 2.7e-30 104.7 2.7 2.7e-30 104.7 2.7 5.1 2 1 2 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KFH43646.1 - 0.0011 18.4 0.0 0.49 9.7 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KFH43646.1 - 0.006 16.6 0.1 0.043 13.8 0.1 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KFH43646.1 - 0.0079 15.5 0.1 0.02 14.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH43646.1 - 0.098 12.9 0.3 0.098 12.9 0.3 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFH43646.1 - 0.11 11.6 0.3 0.23 10.5 0.3 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Git3 PF11710.8 KFH43646.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_S24 PF00717.23 KFH43647.1 - 3.6e-07 30.0 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFH43647.1 - 1.5e-05 24.8 0.0 0.00045 20.0 0.0 2.3 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Alpha-L-AF_C PF06964.12 KFH43648.1 - 1.2e-20 74.3 0.0 1.9e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Orn_Arg_deC_N PF02784.16 KFH43649.1 - 7.3e-83 277.7 0.0 9.5e-83 277.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFH43649.1 - 1.4e-19 70.1 0.0 1.8e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Arm PF00514.23 KFH43650.1 - 1.1e-76 250.7 33.6 1.5e-13 50.3 0.1 11.1 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFH43650.1 - 1.7e-19 69.9 8.7 0.00014 22.3 0.2 8.1 6 2 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KFH43650.1 - 1.3e-17 64.0 9.1 6.9e-05 23.2 0.1 7.0 3 3 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KFH43650.1 - 6.1e-15 54.0 16.1 0.068 13.5 0.3 8.6 10 0 0 10 10 8 4 HEAT repeat Adaptin_N PF01602.20 KFH43650.1 - 2e-12 46.5 7.6 1.8e-07 30.1 0.3 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KFH43650.1 - 3.3e-11 43.1 5.8 1.2e-07 31.5 1.5 2.7 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KFH43650.1 - 3e-09 35.6 1.4 5.9e-09 34.6 1.4 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KFH43650.1 - 4.2e-09 36.1 1.7 2e-05 24.0 0.7 3.2 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFH43650.1 - 6.1e-05 23.1 0.5 23 5.1 0.0 5.1 2 1 5 7 7 7 0 V-ATPase subunit H Cnd1 PF12717.7 KFH43650.1 - 6.8e-05 23.0 8.1 0.073 13.1 0.3 4.8 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KFH43650.1 - 9.4e-05 22.4 6.4 1.3 8.9 0.1 4.1 2 1 2 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 KFH43650.1 - 0.00013 21.4 5.2 0.86 9.0 0.3 4.8 2 2 3 5 5 5 2 Family of unknown function (DUF5578) IFRD PF05004.13 KFH43650.1 - 0.00047 19.4 1.8 1.7 7.7 0.1 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KFH43650.1 - 0.019 15.6 7.7 34 5.5 0.2 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KFH43650.1 - 0.022 14.7 1.2 2.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KFH43650.1 - 0.059 14.0 0.1 4.2 8.0 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KFH43650.1 - 0.89 9.6 9.9 5.7 7.0 0.1 4.5 4 2 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain PI-PLC-X PF00388.19 KFH43651.1 - 5.9e-56 188.1 0.0 1.3e-55 187.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFH43651.1 - 2.3e-42 144.0 0.1 6.4e-42 142.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFH43651.1 - 0.0037 17.7 0.0 0.017 15.6 0.0 2.1 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 KFH43651.1 - 0.0058 17.1 0.1 0.015 15.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Peptidase_M48_N PF16491.5 KFH43653.1 - 5.4e-64 215.4 6.0 5.4e-64 215.4 6.0 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KFH43653.1 - 1.7e-45 155.3 0.0 3.4e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 ClpS PF02617.17 KFH43653.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Peptidase_M56 PF05569.11 KFH43653.1 - 0.11 11.6 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 p450 PF00067.22 KFH43654.1 - 2e-22 79.6 0.4 3.3e-22 78.9 0.4 1.3 1 1 0 1 1 1 1 Cytochrome P450 CBS PF00571.28 KFH43655.1 - 1.4e-27 95.8 7.5 9.4e-10 38.8 0.1 4.3 4 0 0 4 4 4 3 CBS domain RYDR_ITPR PF01365.21 KFH43655.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 RIH domain B56 PF01603.20 KFH43656.1 - 7.3e-193 641.2 3.7 8.6e-193 640.9 3.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFH43656.1 - 5.8e-05 23.0 1.3 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF737 PF05300.11 KFH43656.1 - 0.16 12.3 3.6 0.34 11.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF4826 PF16108.5 KFH43656.1 - 0.19 12.0 1.5 0.36 11.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) TRAPP PF04051.16 KFH43657.1 - 1.2e-42 145.1 0.0 1.4e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Tau95 PF09734.9 KFH43658.1 - 1.2e-40 139.5 0.2 2.1e-40 138.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFH43658.1 - 5.8e-35 120.3 0.0 8.8e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain Zn_clus PF00172.18 KFH43659.1 - 0.12 12.5 14.7 0.5 10.5 14.7 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFH43660.1 - 6.3e-21 74.7 9.9 6.9e-21 74.5 9.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH43660.1 - 0.00062 18.7 4.4 0.00067 18.6 4.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KFH43660.1 - 0.00083 18.7 3.6 0.00096 18.5 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KFH43660.1 - 0.001 17.6 2.1 0.0011 17.4 2.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KFH43660.1 - 0.021 13.1 0.3 0.021 13.1 0.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OmpH PF03938.14 KFH43661.1 - 0.028 14.7 0.5 0.028 14.7 0.5 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc29 PF17082.5 KFH43661.1 - 0.031 14.1 1.4 0.057 13.3 1.4 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Death PF00531.22 KFH43661.1 - 0.035 14.3 0.4 0.07 13.3 0.4 1.4 1 0 0 1 1 1 0 Death domain FAM76 PF16046.5 KFH43661.1 - 0.058 12.7 3.1 0.084 12.2 3.1 1.2 1 0 0 1 1 1 0 FAM76 protein DUF641 PF04859.12 KFH43661.1 - 0.071 13.4 1.2 0.13 12.6 1.1 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) XLF PF09302.11 KFH43661.1 - 0.072 13.3 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Mis14 PF08641.12 KFH43661.1 - 0.082 13.2 0.5 0.082 13.2 0.5 2.0 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Tsc35 PF15079.6 KFH43661.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 FUSC PF04632.12 KFH43661.1 - 0.22 10.0 2.1 0.32 9.5 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KFH43661.1 - 0.34 10.2 5.9 0.53 9.6 5.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 KFH43661.1 - 0.44 9.1 4.8 0.56 8.8 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 KFH43661.1 - 0.79 8.2 7.9 1 7.8 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Csm1_N PF18504.1 KFH43661.1 - 1.3 9.4 5.1 0.23 11.8 0.5 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4748 PF15932.5 KFH43662.1 - 1.2e-20 72.9 1.2 1.2e-20 72.9 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 KFH43662.1 - 1.9e-14 54.2 0.1 5.2e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. p450 PF00067.22 KFH43663.1 - 0.00052 18.9 0.0 0.00052 18.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HAUS6_N PF14661.6 KFH43663.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MtrF PF09472.10 KFH43665.1 - 0.0084 15.5 1.0 0.011 15.1 0.4 1.6 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) APH PF01636.23 KFH43666.1 - 3.3e-15 56.7 0.2 1.4e-14 54.7 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KFH43666.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Ras PF00071.22 KFH43667.1 - 1.8e-31 109.0 0.1 2.2e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH43667.1 - 4.4e-24 85.0 0.1 7.7e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH43667.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFH43667.1 - 0.00044 19.7 0.1 0.00058 19.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KFH43667.1 - 0.004 16.1 0.0 0.4 9.4 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Apc13p PF05839.11 KFH43668.1 - 1.5e-29 102.0 0.1 1.7e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein Porphobil_deam PF01379.20 KFH43669.1 - 2e-74 249.5 0.0 2.7e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFH43669.1 - 2.4e-20 72.7 0.2 5.5e-20 71.5 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain BCS1_N PF08740.11 KFH43670.1 - 8.4e-45 153.1 6.3 8.4e-45 153.1 6.3 2.6 3 0 0 3 3 3 1 BCS1 N terminal AAA PF00004.29 KFH43670.1 - 4e-17 62.9 0.0 1.8e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.9 KFH43670.1 - 0.00015 21.5 30.0 0.00034 20.3 30.0 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RuvB_N PF05496.12 KFH43670.1 - 0.0019 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Macoilin PF09726.9 KFH43670.1 - 0.033 12.8 10.0 0.048 12.2 10.0 1.2 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 KFH43670.1 - 0.047 13.4 20.7 0.12 12.0 20.7 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AAA_16 PF13191.6 KFH43670.1 - 0.06 13.7 0.4 0.2 12.1 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFH43670.1 - 0.073 13.2 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KFH43670.1 - 0.11 12.2 12.9 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFH43670.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC NPR3 PF03666.13 KFH43670.1 - 0.14 10.9 12.9 0.26 10.0 12.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KFH43670.1 - 0.14 12.2 6.3 0.33 11.1 6.3 1.6 1 0 0 1 1 1 0 DDHD domain RRM_1 PF00076.22 KFH43670.1 - 0.16 11.8 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc1_Nup PF09531.10 KFH43670.1 - 0.26 9.9 6.0 0.46 9.1 6.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2151 PF10221.9 KFH43670.1 - 0.7 8.4 9.2 2 6.9 8.7 1.8 2 0 0 2 2 2 0 Cell cycle and development regulator Raftlin PF15250.6 KFH43670.1 - 0.9 8.2 9.6 1.4 7.6 9.6 1.2 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 KFH43670.1 - 1.1 7.4 23.6 1.6 6.9 23.6 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 KFH43670.1 - 1.7 7.8 6.9 2.5 7.2 6.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Hydin_ADK PF17213.3 KFH43670.1 - 1.7 8.8 10.6 14 5.9 10.6 2.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain FAM60A PF15396.6 KFH43670.1 - 2.5 8.0 18.5 5.6 6.9 18.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 KFH43670.1 - 2.7 6.9 10.9 4.3 6.3 10.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 KFH43670.1 - 3.5 6.9 21.2 7.7 5.8 21.2 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger DUF913 PF06025.12 KFH43670.1 - 5.3 5.9 10.3 11 4.8 10.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3827 PF12877.7 KFH43670.1 - 5.9 5.1 15.9 8.8 4.6 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GREB1 PF15782.5 KFH43670.1 - 8.9 3.3 8.9 12 2.8 8.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NDUFA12 PF05071.16 KFH43671.1 - 2.2e-23 82.9 0.0 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4432 PF14486.6 KFH43671.1 - 0.15 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) PBP1_TM PF14812.6 KFH43672.1 - 0.04 14.3 10.6 0.17 12.3 1.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 KFH43672.1 - 7 6.9 11.1 6.2 7.1 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DHHC PF01529.20 KFH43674.1 - 3.9e-39 133.8 9.0 3.9e-39 133.8 9.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Zw10 PF06248.13 KFH43675.1 - 2.3e-10 39.7 0.4 0.00044 19.0 0.8 3.3 3 0 0 3 3 3 3 Centromere/kinetochore Zw10 Zn_clus PF00172.18 KFH43676.1 - 0.00017 21.6 4.7 0.00041 20.4 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSHCT PF08148.12 KFH43676.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Taxilin PF09728.9 KFH43677.1 - 8.1e-90 301.1 57.1 1.2e-89 300.5 57.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 KFH43677.1 - 0.082 13.5 0.2 0.082 13.5 0.2 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF4810) Laminin_I PF06008.14 KFH43677.1 - 0.14 11.8 36.7 0.049 13.3 11.4 3.1 2 1 1 3 3 3 0 Laminin Domain I NPV_P10 PF05531.12 KFH43677.1 - 3.5 8.2 8.7 6.4 7.3 1.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MAD PF05557.13 KFH43677.1 - 8.1 4.7 55.9 9.9 4.4 26.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Rep_fac-A_3 PF08661.11 KFH43678.1 - 6.8e-20 71.4 0.0 6.7e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Replication factor A protein 3 zf-C2H2 PF00096.26 KFH43679.1 - 1.1e-13 50.8 10.8 0.00064 20.0 0.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH43679.1 - 2.7e-13 49.5 10.2 0.063 14.1 0.3 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH43679.1 - 1.3e-06 28.3 12.9 0.019 15.0 0.4 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH43679.1 - 2.4e-06 27.7 2.6 0.39 11.0 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFH43679.1 - 0.00017 21.8 11.1 0.3 11.4 1.4 4.4 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFH43679.1 - 0.00072 19.9 6.6 0.38 11.2 0.4 4.1 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFH43679.1 - 0.00077 19.8 7.7 0.72 10.2 0.1 4.4 2 2 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KFH43679.1 - 0.003 17.9 1.2 0.003 17.9 1.2 5.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_9 PF16293.5 KFH43679.1 - 0.016 15.0 4.1 3 7.7 0.3 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KFH43679.1 - 0.018 15.3 6.9 0.12 12.7 0.7 2.7 2 1 0 2 2 2 0 C2H2-type zinc ribbon HNH_5 PF14279.6 KFH43679.1 - 0.019 14.8 2.7 2.1 8.3 0.0 3.7 3 1 1 4 4 4 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KFH43679.1 - 0.048 13.8 10.8 1.8 8.8 3.1 4.1 2 2 1 3 3 3 0 Zinc ribbon domain zf_C2H2_6 PF18450.1 KFH43679.1 - 0.79 9.5 4.7 25 4.7 0.2 3.4 3 0 0 3 3 3 0 Zinc Finger domain FAM76 PF16046.5 KFH43679.1 - 1 8.6 4.8 0.19 11.1 1.1 1.6 2 0 0 2 2 2 0 FAM76 protein zf_C2H2_ZHX PF18387.1 KFH43679.1 - 2.4 7.9 4.8 0.59 9.8 0.8 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Elf1 PF05129.13 KFH43679.1 - 2.8 8.1 11.7 3.6 7.7 1.2 4.0 4 1 0 4 4 4 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 KFH43679.1 - 2.8 7.8 6.2 5.8 6.8 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KFH43679.1 - 5.3 7.6 8.5 3.7 8.1 0.2 4.1 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Exo_endo_phos PF03372.23 KFH43681.1 - 3.2e-09 36.7 0.1 6.8e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KFH43681.1 - 0.031 15.1 0.1 0.41 11.6 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat bZIP_1 PF00170.21 KFH43682.1 - 5.8e-11 42.3 11.8 1e-10 41.5 11.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFH43682.1 - 4.9e-07 29.7 9.7 4.9e-07 29.7 9.7 2.0 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFH43682.1 - 8.1e-05 23.1 6.0 8.1e-05 23.1 6.0 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor Prefoldin_2 PF01920.20 KFH43682.1 - 0.0081 16.1 1.6 0.016 15.2 1.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit Lectin_N PF03954.14 KFH43682.1 - 0.012 15.3 1.8 0.02 14.6 1.6 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Macoilin PF09726.9 KFH43682.1 - 0.11 11.1 9.9 0.16 10.5 9.9 1.1 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 KFH43682.1 - 0.16 9.9 3.5 0.21 9.5 3.5 1.0 1 0 0 1 1 1 0 Prominin DivIC PF04977.15 KFH43682.1 - 0.2 11.4 2.1 0.44 10.3 2.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Med3 PF11593.8 KFH43682.1 - 0.39 9.9 9.6 0.67 9.1 9.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal V_ATPase_I PF01496.19 KFH43682.1 - 1.1 7.1 3.0 1.3 6.9 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L4 PF00573.22 KFH43685.1 - 2.6e-46 157.7 0.0 3.8e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.20 KFH43687.1 - 3.6e-07 30.6 0.0 6.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ADH_zinc_N PF00107.26 KFH43689.1 - 6.6e-19 68.2 0.9 1.1e-18 67.5 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43689.1 - 1.3e-08 36.0 0.0 3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH43689.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KFH43689.1 - 0.0044 16.3 0.4 0.0074 15.6 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_61 PF03443.14 KFH43691.1 - 8.4e-45 153.2 0.0 1e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribonuc_L-PSP PF01042.21 KFH43693.1 - 8.9e-25 87.1 0.0 9.8e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ETF_alpha PF00766.19 KFH43693.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain ORC4_C PF14629.6 KFH43694.1 - 1.7e-66 223.7 0.0 2.6e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KFH43694.1 - 9e-12 45.7 0.1 2.3e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 KFH43694.1 - 1.3e-11 43.8 3.8 1.3e-11 43.8 3.8 1.7 2 0 0 2 2 1 1 PHD-finger PHD PF00628.29 KFH43694.1 - 2.5e-10 40.1 7.5 4.1e-10 39.4 7.5 1.4 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.12 KFH43694.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFH43694.1 - 3.9e-07 30.4 0.0 7.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFH43694.1 - 8.3e-07 29.5 0.0 2.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFH43694.1 - 8.5e-05 22.9 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain FYVE_2 PF02318.16 KFH43694.1 - 0.00059 20.0 0.6 0.0012 19.1 0.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger NB-ARC PF00931.22 KFH43694.1 - 0.0007 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KFH43694.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 KFH43694.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFH43694.1 - 0.0015 18.6 0.0 0.004 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFH43694.1 - 0.0019 18.2 0.0 0.0045 16.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KFH43694.1 - 0.0024 17.1 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) C1_1 PF00130.22 KFH43694.1 - 0.0045 16.8 0.6 0.0096 15.8 0.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_29 PF13555.6 KFH43694.1 - 0.0066 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ORC2 PF04084.14 KFH43694.1 - 0.011 14.7 0.3 0.097 11.6 0.0 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 2 cobW PF02492.19 KFH43694.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFH43694.1 - 0.026 15.0 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFH43694.1 - 0.035 14.6 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KFH43694.1 - 0.048 12.6 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KFH43694.1 - 0.053 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 KFH43694.1 - 0.053 12.9 0.0 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 KFH43694.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KFH43694.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KFH43694.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFH43694.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KFH43694.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Roc PF08477.13 KFH43694.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KFH43694.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KFH43694.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 KFH43694.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KFH43694.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Prok-RING_1 PF14446.6 KFH43694.1 - 0.24 11.4 3.9 0.63 10.0 3.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KFH43694.1 - 0.28 11.5 3.3 0.18 12.1 0.6 2.0 2 0 0 2 2 2 0 C1 domain zf-PHD-like PF15446.6 KFH43694.1 - 0.36 10.4 3.0 0.86 9.2 3.0 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DZR PF12773.7 KFH43694.1 - 4.3 7.4 6.0 20 5.3 6.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF2655 PF10848.8 KFH43695.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) MFS_1 PF07690.16 KFH43696.1 - 1e-28 100.3 30.0 1.3e-28 100.0 30.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KFH43696.1 - 0.11 12.2 0.9 0.32 10.8 0.0 2.2 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YtpI PF14007.6 KFH43696.1 - 0.2 11.8 2.0 1.4 9.1 1.5 2.7 2 0 0 2 2 2 0 YtpI-like protein LtrA PF06772.11 KFH43697.1 - 2.5e-16 59.8 22.1 2.5e-16 59.8 22.1 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Sulf_transp PF04143.14 KFH43698.1 - 2.2e-34 119.5 26.5 2.2e-34 119.5 26.5 1.8 1 1 0 1 1 1 1 Sulphur transport AAA PF00004.29 KFH43699.1 - 1.2e-49 168.1 0.0 3.1e-39 134.4 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH43699.1 - 1.6e-10 40.6 0.5 2.9e-08 33.4 0.3 2.9 2 1 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KFH43699.1 - 1.6e-07 31.8 0.2 0.0027 18.1 0.0 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFH43699.1 - 7.8e-06 25.9 0.0 0.3 11.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH43699.1 - 0.00025 21.3 5.8 1.7 8.9 0.1 4.7 3 2 2 5 5 5 1 AAA domain RuvB_N PF05496.12 KFH43699.1 - 0.0014 18.4 0.0 0.0085 15.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFH43699.1 - 0.0015 18.9 0.0 2.9 8.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 KFH43699.1 - 0.0021 18.0 3.3 0.87 9.5 0.2 3.5 4 1 1 5 5 4 1 NACHT domain AAA_14 PF13173.6 KFH43699.1 - 0.0027 17.7 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KFH43699.1 - 0.0056 16.9 0.0 0.099 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Phage_holin_6_1 PF09682.10 KFH43699.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) AAA_25 PF13481.6 KFH43699.1 - 0.015 14.9 0.6 6.3 6.3 0.0 3.6 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 KFH43699.1 - 0.07 12.6 0.1 14 5.2 0.0 2.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KFH43699.1 - 0.072 13.0 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 KFH43699.1 - 0.11 12.9 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KFH43699.1 - 0.13 12.3 0.0 15 5.7 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KFH43699.1 - 0.13 11.6 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF383 PF04063.14 KFH43700.1 - 4.7e-67 225.4 0.0 2.3e-65 219.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF383) DUF384 PF04064.13 KFH43700.1 - 5.2e-23 80.6 1.3 1.3e-22 79.4 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) F-box-like PF12937.7 KFH43701.1 - 1.5e-07 31.2 0.3 3.2e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH43701.1 - 0.0013 18.6 0.5 0.0033 17.3 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFH43701.1 - 0.085 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 F-box Acetyltransf_1 PF00583.25 KFH43702.1 - 4.1e-16 59.3 0.2 8.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH43702.1 - 7.9e-11 42.2 0.1 5.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH43702.1 - 6.6e-10 39.0 0.0 2.9e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH43702.1 - 1.4e-08 34.6 0.2 0.00013 21.9 0.0 2.9 3 1 0 3 3 3 2 FR47-like protein Acetyltransf_3 PF13302.7 KFH43702.1 - 3.5e-05 24.5 0.7 0.0014 19.3 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFH43702.1 - 0.031 14.4 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KFH43702.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S24 PF00717.23 KFH43704.1 - 0.00053 19.9 0.4 0.0014 18.6 0.4 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFH43704.1 - 0.012 15.4 0.1 0.57 10.0 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 WD40 PF00400.32 KFH43706.1 - 1.5e-12 47.8 1.5 0.032 15.1 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43706.1 - 0.0029 17.9 0.0 1.4 9.3 0.0 3.6 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_9 PF14658.6 KFH43707.1 - 9.3e-13 48.3 0.0 2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFH43707.1 - 1e-12 48.3 0.3 6.1e-08 33.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFH43707.1 - 1.5e-09 37.0 0.7 0.006 16.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFH43707.1 - 6.1e-09 34.8 0.5 0.021 14.3 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFH43707.1 - 1.3e-06 28.1 0.3 0.00011 22.0 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair Cpn10 PF00166.21 KFH43708.1 - 1.4e-29 101.9 0.0 1.6e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit CoA_binding_2 PF13380.6 KFH43709.1 - 1.5e-27 96.4 0.1 1.8e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KFH43709.1 - 0.074 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain MT-A70 PF05063.14 KFH43710.1 - 3.7e-35 121.4 0.0 5e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Zn_clus PF00172.18 KFH43712.1 - 1.8e-06 27.9 8.4 3.3e-06 27.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFH43713.1 - 3.8e-49 167.4 0.0 1.9e-48 165.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43713.1 - 1.3e-22 80.4 0.0 2.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH43713.1 - 0.004 17.1 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH43713.1 - 0.043 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFH43713.1 - 0.22 10.8 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CDC73_C PF05179.14 KFH43714.1 - 4.4e-56 188.9 0.0 6.1e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal KH_8 PF17903.1 KFH43715.1 - 7.3e-31 106.1 0.0 1.8e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Pfg27 PF09216.10 KFH43715.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Pfg27 Acyltransf_C PF16076.5 KFH43715.1 - 0.021 14.9 0.5 0.15 12.1 0.3 2.3 2 0 0 2 2 2 0 Acyltransferase C-terminus KH_1 PF00013.29 KFH43715.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 KH domain RGS PF00615.19 KFH43716.1 - 3e-38 130.7 0.5 8.8e-38 129.2 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KFH43716.1 - 8.6e-23 80.2 0.0 2.8e-19 69.0 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KFH43716.1 - 0.011 15.8 0.3 0.09 12.8 0.0 2.4 3 0 0 3 3 3 0 Replication-relaxation Glycos_transf_2 PF00535.26 KFH43718.1 - 2.2e-24 86.1 0.0 6.9e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFH43718.1 - 8.5e-09 35.6 0.1 4.2e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFH43718.1 - 0.00045 19.8 0.0 0.00091 18.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1449 PF07290.11 KFH43718.1 - 0.7 9.5 4.7 3.7 7.1 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) YqeY PF09424.10 KFH43719.1 - 9.5e-15 54.9 7.8 1.3e-14 54.5 7.8 1.1 1 0 0 1 1 1 1 Yqey-like protein Trypsin PF00089.26 KFH43720.1 - 3.1e-12 46.8 0.0 5.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFH43720.1 - 2.7e-09 38.1 0.2 5e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PBP_N PF17093.5 KFH43720.1 - 0.085 13.1 0.1 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Methyltransf_23 PF13489.6 KFH43721.1 - 1.3e-16 60.9 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43721.1 - 3.4e-14 53.3 0.0 1.7e-13 51.1 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH43721.1 - 7.4e-12 45.9 0.0 1.3e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH43721.1 - 1.2e-11 45.1 0.0 4.8e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH43721.1 - 1.3e-10 41.3 0.0 3.3e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH43721.1 - 4.2e-07 29.6 0.0 1.5e-05 24.5 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFH43721.1 - 6.3e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KFH43721.1 - 0.0023 17.2 0.0 0.0076 15.6 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFH43721.1 - 0.0035 16.9 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KFH43721.1 - 0.02 15.0 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KFH43721.1 - 0.062 13.1 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KFH43721.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_PK PF05891.12 KFH43721.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_M3 PF01432.20 KFH43722.1 - 5.5e-145 484.1 0.0 7e-145 483.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 SMK-1 PF04802.15 KFH43724.1 - 2.3e-84 282.0 1.8 5e-84 280.9 1.8 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Vps53_N PF04100.12 KFH43724.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal SEEEED PF14797.6 KFH43724.1 - 0.87 9.8 13.7 1.6 8.9 13.7 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Roughex PF06020.11 KFH43724.1 - 2.2 7.3 6.8 3.9 6.5 6.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Ras PF00071.22 KFH43725.1 - 1.3e-64 216.7 0.0 1.6e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH43725.1 - 6.2e-34 116.8 0.0 1.1e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH43725.1 - 5.4e-13 48.8 0.0 5.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH43725.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFH43725.1 - 0.00027 20.4 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFH43725.1 - 0.0041 17.2 0.0 0.0077 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH43725.1 - 0.0053 16.7 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFH43725.1 - 0.028 13.9 0.0 0.036 13.5 0.0 1.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KFH43725.1 - 0.041 14.3 0.0 8.2 6.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFH43725.1 - 0.063 12.8 0.0 0.31 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KFH43725.1 - 0.12 12.7 0.1 0.75 10.1 0.0 2.0 1 1 0 2 2 2 0 AAA domain SE PF08491.10 KFH43726.1 - 6e-86 287.9 0.0 8e-86 287.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KFH43726.1 - 2.3e-09 37.3 0.2 2.8e-06 27.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFH43726.1 - 9.6e-09 34.9 1.9 1.4e-07 31.1 1.9 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH43726.1 - 0.00014 22.0 0.1 0.00036 20.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFH43726.1 - 0.00017 20.8 0.4 0.0059 15.7 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFH43726.1 - 0.00068 18.8 0.9 0.0027 16.9 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFH43726.1 - 0.00091 18.5 0.0 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 KFH43726.1 - 0.004 16.8 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KFH43726.1 - 0.0049 16.2 0.3 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH43726.1 - 0.0082 16.7 2.2 0.088 13.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH43726.1 - 0.0089 15.4 1.0 0.015 14.7 1.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFH43726.1 - 0.034 14.0 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFH43726.1 - 0.038 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KFH43726.1 - 0.22 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bystin PF05291.11 KFH43727.1 - 4.7e-133 443.0 0.0 5.8e-133 442.7 0.0 1.1 1 0 0 1 1 1 1 Bystin 7tm_2 PF00002.24 KFH43729.1 - 0.00017 21.0 8.3 0.00017 21.0 8.3 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFH43729.1 - 0.0012 18.1 9.5 0.0012 18.1 9.5 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KFH43729.1 - 0.0034 17.2 9.8 0.006 16.4 9.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 EptA_B_N PF08019.12 KFH43729.1 - 0.059 13.3 0.3 0.059 13.3 0.3 2.2 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB EIF_2_alpha PF07541.12 KFH43730.1 - 3.5e-38 130.3 0.0 6.7e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFH43730.1 - 1.4e-13 51.0 0.7 2.7e-13 50.1 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF5427 PF10310.9 KFH43731.1 - 0.07 12.1 0.2 0.07 12.1 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Kelch_5 PF13854.6 KFH43733.1 - 8.4e-11 41.6 7.9 1.6e-10 40.8 1.6 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KFH43733.1 - 0.0011 19.2 6.1 0.0013 18.9 0.3 3.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KFH43733.1 - 0.0016 18.6 3.1 0.043 14.1 0.2 4.2 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 KFH43733.1 - 0.0028 17.6 2.9 0.17 11.9 0.4 4.1 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KFH43733.1 - 0.033 13.8 3.2 1 9.0 0.4 3.1 3 0 0 3 3 3 0 Kelch motif DUF3262 PF11660.8 KFH43733.1 - 0.044 14.2 0.7 0.044 14.2 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) SKG6 PF08693.10 KFH43733.1 - 0.88 9.0 2.6 3.1 7.3 2.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L23 PF00276.20 KFH43734.1 - 3.6e-11 43.3 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 MRP-S26 PF14943.6 KFH43734.1 - 0.0049 16.8 3.9 0.0067 16.4 3.6 1.5 1 1 0 1 1 1 1 Mitochondrial ribosome subunit S26 Toxin_8 PF07365.12 KFH43735.1 - 0.019 15.1 0.4 0.027 14.7 0.4 1.3 1 0 0 1 1 1 0 Alpha conotoxin precursor Glyco_hydro_61 PF03443.14 KFH43736.1 - 4.6e-51 173.7 0.0 7.4e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ArenaCapSnatch PF17296.2 KFH43736.1 - 0.28 10.6 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain Chitin_bind_1 PF00187.19 KFH43736.1 - 1.3 9.5 30.3 0.2 12.2 23.5 2.8 2 0 0 2 2 2 0 Chitin recognition protein BIR PF00653.21 KFH43737.1 - 6.1e-44 148.5 5.6 4.2e-21 75.4 0.9 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mito_carr PF00153.27 KFH43738.1 - 3.5e-60 199.9 0.0 2.3e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KFH43739.1 - 1.3e-62 207.7 2.0 5.8e-22 77.4 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Ectatomin PF06457.11 KFH43739.1 - 0.042 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Ectatomin Serine_protease PF18405.1 KFH43739.1 - 0.046 12.9 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Ribosomal_L11 PF00298.19 KFH43740.1 - 1.8e-27 95.7 0.1 2.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFH43740.1 - 5.1e-26 90.3 0.1 8.9e-26 89.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF1917 PF08939.10 KFH43742.1 - 4.4e-85 285.8 0.7 6.7e-85 285.2 0.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Jak1_Phl PF17887.1 KFH43742.1 - 0.16 11.9 0.4 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain CDP-OH_P_transf PF01066.21 KFH43743.1 - 4.9e-15 56.0 0.3 1.2e-14 54.8 0.3 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PH PF00169.29 KFH43744.1 - 5.3e-05 23.7 0.1 0.00013 22.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 KFH43744.1 - 0.066 11.2 0.5 0.11 10.4 0.5 1.3 1 0 0 1 1 1 0 Prominin Tup_N PF08581.10 KFH43744.1 - 3.7 7.9 6.2 4.2 7.8 0.2 3.2 3 0 0 3 3 3 0 Tup N-terminal p450 PF00067.22 KFH43745.1 - 7.2e-11 41.5 0.0 8.9e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SARAF PF06682.12 KFH43746.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MitoNEET_N PF10660.9 KFH43746.1 - 0.094 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Chordopox_A13L PF05961.11 KFH43746.1 - 0.19 12.0 3.1 0.32 11.3 3.1 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Methyltransf_23 PF13489.6 KFH43747.1 - 1e-23 84.0 0.0 1.5e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43747.1 - 3.5e-13 50.1 0.0 1e-12 48.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH43747.1 - 1.5e-10 41.6 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH43747.1 - 2.2e-08 34.8 0.0 1.7e-07 31.9 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH43747.1 - 6.1e-06 26.1 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KFH43747.1 - 0.00084 18.7 0.0 0.021 14.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KFH43747.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFH43747.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KFH43747.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KFH43747.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KFH43747.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KFH43747.1 - 0.085 12.1 0.0 0.45 9.8 0.0 2.1 3 0 0 3 3 3 0 O-methyltransferase domain PCMT PF01135.19 KFH43747.1 - 0.25 11.1 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KFH43748.1 - 8.4e-68 228.6 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43748.1 - 8.6e-32 110.4 0.0 1.1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH43748.1 - 0.00026 20.4 0.2 0.00042 19.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFH43748.1 - 0.0031 16.5 0.2 0.0064 15.5 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFH43748.1 - 0.0095 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH43748.1 - 0.027 14.4 0.2 0.053 13.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFH43748.1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 KFH43748.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 RPAP1_C PF08620.10 KFH43750.1 - 1.3e-27 95.6 0.0 2.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KFH43750.1 - 1.1e-16 60.3 2.5 2.1e-16 59.4 2.5 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal GIDA_assoc PF13932.6 KFH43750.1 - 0.0042 17.3 0.1 0.006 16.8 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain LCAT PF02450.15 KFH43751.1 - 7.1e-109 364.5 0.1 8.6e-109 364.3 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFH43751.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Whi5 PF08528.11 KFH43752.1 - 2.3e-10 39.8 0.1 3.8e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Whi5 like GTP_EFTU PF00009.27 KFH43754.1 - 1.9e-33 115.7 4.2 5.3e-32 110.9 4.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFH43754.1 - 4.5e-25 87.8 1.6 1.2e-24 86.4 1.6 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFH43754.1 - 1.1e-10 41.6 0.2 3.2e-10 40.1 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH43754.1 - 7.6e-07 29.2 1.1 3.7e-05 23.7 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 KFH43754.1 - 5.1e-05 23.6 2.2 0.43 11.0 0.4 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.10 KFH43754.1 - 5.3e-05 22.7 0.2 0.0002 20.8 0.2 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFH43754.1 - 7e-05 22.4 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family IF2_N PF04760.15 KFH43754.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 KFH43754.1 - 0.00024 20.6 0.3 0.00066 19.2 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KFH43754.1 - 0.0016 18.6 0.1 0.004 17.4 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFH43754.1 - 0.0044 17.5 2.1 22 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFH43754.1 - 0.011 15.5 0.1 0.03 14.0 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFH43754.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 KFH43754.1 - 0.048 13.5 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Secretin_N_2 PF07655.13 KFH43754.1 - 4.1 8.0 6.8 0.26 11.9 0.7 2.2 2 0 0 2 2 1 0 Secretin N-terminal domain Fungal_trans_2 PF11951.8 KFH43755.1 - 1.6e-11 43.6 0.0 3.5e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43755.1 - 1.2e-06 28.5 13.1 2.5e-06 27.5 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSA PF07529.13 KFH43755.1 - 0.053 13.9 1.3 0.15 12.4 1.3 1.7 1 0 0 1 1 1 0 HSA Transglut_core2 PF13369.6 KFH43756.1 - 3.9e-21 75.2 0.0 7.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KFH43756.1 - 1.1e-11 45.0 0.0 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KFH43756.1 - 0.00014 21.7 0.6 0.00014 21.7 0.6 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFH43756.1 - 0.0013 18.6 0.1 0.0031 17.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain VHS PF00790.19 KFH43757.1 - 2.2e-45 154.0 0.0 5.6e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFH43757.1 - 3.3e-20 72.4 0.0 7.8e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KFH43757.1 - 5e-19 68.4 0.1 5e-19 68.4 0.1 2.1 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KFH43757.1 - 3.7e-07 29.6 0.0 9.5e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 GGA N-GAT domain AP3B1_C PF14796.6 KFH43757.1 - 0.01 16.1 0.4 0.031 14.5 0.1 2.0 1 1 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal DUF1918 PF08940.11 KFH43758.1 - 0.011 15.3 1.8 19 5.0 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) I-set PF07679.16 KFH43758.1 - 0.012 15.7 0.5 0.91 9.6 0.3 3.4 3 0 0 3 3 3 0 Immunoglobulin I-set domain DEC-1_N PF04625.13 KFH43758.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SURF6 PF04935.12 KFH43759.1 - 8.1e-51 172.7 37.6 8.1e-51 172.7 37.6 5.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KFH43759.1 - 4e-16 59.3 0.4 4e-16 59.3 0.4 6.9 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 CoA_trans PF01144.23 KFH43760.1 - 8e-99 329.4 0.5 4.2e-60 202.8 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFH43760.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SET PF00856.28 KFH43761.1 - 3.6e-14 53.5 0.1 3.7e-13 50.2 0.1 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KFH43761.1 - 0.089 13.4 0.2 3.6 8.3 0.0 2.6 3 0 0 3 3 3 0 SAF domain Pribosyl_synth PF14572.6 KFH43761.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Phage_int_SAM_1 PF02899.17 KFH43761.1 - 0.098 13.0 1.2 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Glyco_hydro_26 PF02156.15 KFH43762.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 PP28 PF10252.9 KFH43763.1 - 7.5e-30 103.2 12.0 7.5e-30 103.2 12.0 3.5 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CENP-B_dimeris PF09026.10 KFH43763.1 - 5.4 7.5 36.9 0.96 9.9 5.5 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2013 PF09431.10 KFH43764.1 - 1.8e-52 177.2 1.0 3.3e-52 176.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Acetyltransf_1 PF00583.25 KFH43765.1 - 3e-18 66.1 0.0 4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH43765.1 - 4.2e-10 39.7 0.0 6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH43765.1 - 3.2e-09 36.6 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFH43765.1 - 5.6e-09 36.3 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH43765.1 - 7.8e-07 29.2 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFH43765.1 - 8.9e-07 29.7 0.0 1.3e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFH43765.1 - 1.8e-05 24.4 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFH43765.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4105 PF13387.6 KFH43765.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Acetyltransf_18 PF18014.1 KFH43765.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec23_trunk PF04811.15 KFH43766.1 - 5.7e-70 235.6 0.0 8.4e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFH43766.1 - 2.4e-23 81.9 0.0 9.8e-23 79.9 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFH43766.1 - 1.3e-17 64.3 0.0 2.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFH43766.1 - 2.8e-17 62.4 4.9 5e-17 61.7 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFH43766.1 - 2.4e-09 37.0 0.0 5.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFH43766.1 - 0.019 14.3 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Metallopep PF12044.8 KFH43767.1 - 7.6e-163 542.1 0.0 1.1e-162 541.6 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KFH43767.1 - 0.0036 17.2 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 KFH43767.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KFH43767.1 - 0.22 12.0 2.2 0.67 10.5 2.2 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Gar1 PF04410.14 KFH43768.1 - 5.1e-39 133.5 0.0 6.2e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 2-oxoacid_dh PF00198.23 KFH43769.1 - 1.7e-80 269.8 0.3 2.4e-80 269.4 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFH43769.1 - 3.2e-15 55.7 1.8 7.2e-15 54.6 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFH43769.1 - 0.043 13.6 0.1 0.13 12.1 0.1 1.8 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 KFH43769.1 - 0.088 13.5 0.1 5.3 7.8 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.8 KFH43769.1 - 0.4 11.2 0.0 0.4 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Trypan_PARP PF05887.11 KFH43769.1 - 0.52 10.3 21.4 0.94 9.5 21.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM76 PF16046.5 KFH43769.1 - 1 8.7 5.3 19 4.5 3.8 2.1 2 0 0 2 2 2 0 FAM76 protein DUF2052 PF09747.9 KFH43769.1 - 1.5 8.9 6.0 2.4 8.3 6.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 KFH43769.1 - 2.9 6.6 7.4 4.3 6.0 7.4 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KFH43769.1 - 5.5 6.7 8.2 7.7 6.3 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 KFH43769.1 - 9.8 4.7 10.3 14 4.2 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.22 KFH43770.1 - 3e-48 164.7 0.0 3.5e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.11 KFH43771.1 - 3.3e-77 258.8 0.0 4.9e-76 254.9 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFH43771.1 - 2e-05 25.2 0.0 3.9 8.5 0.0 5.1 3 2 1 4 4 4 2 WD domain, G-beta repeat TLD PF07534.16 KFH43772.1 - 5.1e-27 94.8 0.0 1.6e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 TLD CP2 PF04516.15 KFH43773.1 - 3.4e-80 268.7 0.0 5.9e-80 267.9 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor Syndecan PF01034.20 KFH43774.1 - 0.016 15.2 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Ribo_biogen_C PF04034.13 KFH43775.1 - 3.3e-50 169.1 0.0 4.5e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFH43775.1 - 9.3e-13 47.8 0.6 1.7e-12 46.9 0.6 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cnn_1N PF07989.11 KFH43776.1 - 2e-26 91.9 3.9 2e-26 91.9 3.9 13.9 4 3 9 13 13 12 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KFH43776.1 - 1.1e-24 86.7 2.6 1.1e-24 86.7 2.6 3.8 3 0 0 3 3 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KFH43776.1 - 1.4e-11 43.9 144.2 0.00093 18.2 18.5 7.6 1 1 6 7 7 7 5 Spc7 kinetochore protein AAA_13 PF13166.6 KFH43776.1 - 1.5e-06 27.2 21.9 1.5e-06 27.2 21.9 5.3 1 1 5 6 6 6 1 AAA domain Lebercilin PF15619.6 KFH43776.1 - 0.00046 19.9 21.8 0.00046 19.9 21.8 9.3 2 2 9 11 11 11 4 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 KFH43776.1 - 0.0019 18.1 13.0 0.0019 18.1 13.0 12.9 7 2 4 12 12 12 4 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KFH43776.1 - 0.0046 16.3 136.1 0.011 15.1 24.9 8.4 1 1 5 7 7 7 4 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KFH43776.1 - 0.0053 16.8 0.5 0.0053 16.8 0.5 11.2 3 3 10 13 13 11 5 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 KFH43776.1 - 0.087 12.3 127.4 0.14 11.6 18.0 6.9 1 1 5 6 6 6 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 KFH43776.1 - 0.098 13.1 136.6 0.8 10.1 15.7 7.8 1 1 5 6 6 5 0 Fez1 Fumble PF03630.14 KFH43776.1 - 0.11 11.7 0.1 0.32 10.1 0.1 1.8 1 0 0 1 1 1 0 Fumble Bacillus_HBL PF05791.11 KFH43776.1 - 1.5 8.6 63.4 0.42 10.4 3.3 7.9 4 2 3 7 7 7 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 KFH43776.1 - 2.3 8.4 182.3 0.064 13.5 15.4 10.8 1 1 11 12 12 12 0 Autophagy protein 16 (ATG16) ATG_C PF09333.11 KFH43776.1 - 9.6 6.6 6.8 3 8.3 0.3 3.6 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain HUN PF08729.10 KFH43777.1 - 3.7e-07 30.0 0.2 7.9e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain FXMRP1_C_core PF12235.8 KFH43777.1 - 0.79 10.4 7.3 5.2 7.7 7.3 2.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Peptidase_C12 PF01088.21 KFH43778.1 - 4.9e-57 193.1 0.0 3.9e-56 190.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 GPP34 PF05719.11 KFH43779.1 - 1.5e-69 234.1 0.6 2e-69 233.7 0.6 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Nrap_D5 PF17406.2 KFH43780.1 - 2.1e-63 212.9 0.0 2e-61 206.5 0.1 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KFH43780.1 - 6.4e-58 195.6 0.0 1e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KFH43780.1 - 1.6e-48 164.3 0.0 8.8e-45 152.2 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KFH43780.1 - 2.3e-46 157.6 0.1 3.8e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KFH43780.1 - 3.5e-42 144.2 0.0 6.5e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFH43780.1 - 2.3e-32 112.1 0.0 7e-32 110.5 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 6 WD40 PF00400.32 KFH43782.1 - 0.0068 17.2 0.4 0.68 10.9 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43782.1 - 0.02 15.2 0.0 0.12 12.6 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MRFAP1 PF15155.6 KFH43783.1 - 0.0097 16.4 0.1 0.02 15.4 0.1 1.4 1 0 0 1 1 1 1 MORF4 family-associated protein1 Methyltransf_PK PF05891.12 KFH43784.1 - 4.8e-72 242.0 0.0 5.5e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFH43784.1 - 7.6e-05 23.3 0.0 0.00076 20.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH43784.1 - 9.1e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFH43784.1 - 0.032 13.5 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_11 PF08241.12 KFH43784.1 - 0.1 13.2 0.0 0.44 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_1 PF00583.25 KFH43785.1 - 6.7e-09 36.0 0.0 8.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH43785.1 - 2.7e-07 30.9 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH43785.1 - 9.8e-06 25.5 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 KFH43786.1 - 7.4e-44 150.1 0.0 4e-42 144.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.24 KFH43787.1 - 4.8e-46 157.5 0.0 8.9e-46 156.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Glyco_tranf_2_4 PF13704.6 KFH43787.1 - 0.17 12.4 0.0 0.56 10.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Phosphoesterase PF04185.14 KFH43789.1 - 6.9e-06 25.5 0.0 7.3e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoesterase family MTP18 PF10558.9 KFH43789.1 - 0.097 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) GMC_oxred_N PF00732.19 KFH43790.1 - 4.8e-55 187.0 0.0 6.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH43790.1 - 1.8e-29 103.1 0.0 3.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFH43790.1 - 2.7e-05 23.5 0.5 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFH43790.1 - 3.5e-05 23.0 0.1 5.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KFH43790.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFH43790.1 - 0.032 13.8 0.6 0.59 9.7 0.4 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFH43790.1 - 0.034 13.4 0.4 6.4 5.9 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KFH43790.1 - 0.046 12.6 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KFH43790.1 - 0.097 12.9 0.2 0.32 11.3 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lipase_3 PF01764.25 KFH43791.1 - 1.4e-15 57.4 0.0 1.8e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) adh_short_C2 PF13561.6 KFH43792.1 - 5.4e-54 183.2 0.0 6.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43792.1 - 2.4e-48 164.2 0.2 5e-48 163.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFH43792.1 - 5.2e-11 42.8 0.4 8.6e-11 42.1 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFH43792.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 KFH43792.1 - 0.12 12.0 1.1 0.15 11.7 0.1 1.6 2 0 0 2 2 2 0 SLOG cluster4 family DUF3637 PF12337.8 KFH43792.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) F420_oxidored PF03807.17 KFH43792.1 - 0.16 12.6 0.9 2.9 8.5 0.3 2.7 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Response_reg PF00072.24 KFH43793.1 - 1.4e-21 76.7 0.0 4.2e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain CENP-B_dimeris PF09026.10 KFH43793.1 - 0.068 13.6 2.3 0.23 11.8 2.3 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2052 PF09747.9 KFH43794.1 - 3.5e-25 89.3 9.7 5.4e-23 82.2 9.7 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Mito_carr PF00153.27 KFH43795.1 - 7.5e-72 237.3 2.2 2.3e-23 81.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 3-dmu-9_3-mt PF06983.13 KFH43796.1 - 5e-45 152.8 0.2 8.1e-45 152.1 0.2 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase PRP21_like_P PF12230.8 KFH43797.1 - 3e-56 190.7 14.1 2.2e-55 187.9 14.1 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KFH43797.1 - 3.3e-41 139.0 1.9 2.6e-20 72.1 0.1 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KFH43797.1 - 0.0012 18.4 0.6 0.0022 17.6 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF2439 PF10382.9 KFH43799.1 - 6.4e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) dCMP_cyt_deam_1 PF00383.23 KFH43800.1 - 1.6e-20 72.9 0.0 5.5e-20 71.1 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFH43800.1 - 2.1e-17 63.2 0.1 6.2e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KFH43800.1 - 0.0059 16.7 0.1 0.068 13.2 0.0 2.7 3 0 0 3 3 3 1 Bd3614-like deaminase PMT PF02366.18 KFH43802.1 - 9.3e-83 277.6 16.3 1.8e-82 276.6 16.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFH43802.1 - 5.1e-67 225.3 11.8 5.1e-67 225.3 11.8 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFH43802.1 - 9.9e-47 159.2 0.0 1.8e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain Corona_nucleoca PF00937.18 KFH43802.1 - 0.26 10.3 4.4 0.11 11.5 0.5 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Phosphoesterase PF04185.14 KFH43804.1 - 3.3e-09 36.4 0.0 5.1e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoesterase family LrgB PF04172.16 KFH43804.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 LrgB-like family Glyco_hydro_61 PF03443.14 KFH43806.1 - 1.1e-69 234.5 0.0 1.3e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.12 KFH43807.1 - 1.4e-27 95.7 1.5 3.3e-27 94.5 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43807.1 - 3.1e-16 59.5 1.0 5.2e-16 58.8 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH43807.1 - 1.8e-10 40.6 0.4 0.00023 20.7 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFH43807.1 - 0.0015 17.9 1.9 0.0015 17.9 1.9 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFH43807.1 - 0.0021 17.2 4.3 0.003 16.7 4.3 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KFH43807.1 - 0.017 14.7 1.0 0.04 13.5 0.2 2.0 1 1 2 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KFH43807.1 - 0.033 14.6 0.4 0.063 13.7 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFH43807.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KFH43807.1 - 0.11 11.8 0.5 0.15 11.3 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KFH43807.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KFH43807.1 - 0.12 11.0 1.2 0.18 10.5 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein SET PF00856.28 KFH43808.1 - 4.5e-15 56.4 0.0 8.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 SET domain SNARE PF05739.19 KFH43810.1 - 2.7e-14 52.9 0.1 2.7e-14 52.9 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KFH43810.1 - 9.9e-10 37.4 1.5 2.8e-09 35.9 1.5 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KFH43810.1 - 0.00089 19.0 0.2 0.00089 19.0 0.2 3.3 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 KFH43810.1 - 0.0024 18.1 5.7 0.17 12.2 0.1 3.4 4 0 0 4 4 4 2 Uncharacterized conserved protein Prominin PF05478.11 KFH43810.1 - 0.007 14.4 2.7 0.5 8.3 0.1 2.2 2 0 0 2 2 2 2 Prominin Syntaxin-18_N PF10496.9 KFH43810.1 - 0.0077 16.5 2.6 0.028 14.7 0.7 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus TRPM_tetra PF16519.5 KFH43810.1 - 0.02 15.0 0.1 0.02 15.0 0.1 2.8 3 0 0 3 3 3 0 Tetramerisation domain of TRPM SF-assemblin PF06705.11 KFH43810.1 - 0.13 11.6 5.6 0.2 10.9 1.3 2.5 2 1 0 2 2 2 0 SF-assemblin/beta giardin NPV_P10 PF05531.12 KFH43810.1 - 0.32 11.5 4.8 48 4.5 1.8 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 KFH43810.1 - 1.1 9.0 11.7 0.097 12.5 0.9 2.8 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 KFH43810.1 - 2 8.9 6.6 1.7 9.2 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 RTA1 PF04479.13 KFH43811.1 - 1.8e-66 223.7 13.0 1.8e-66 223.7 13.0 1.8 1 1 1 2 2 2 1 RTA1 like protein Caveolin PF01146.17 KFH43811.1 - 2.1 8.3 6.5 0.15 12.0 0.8 2.0 2 0 0 2 2 2 0 Caveolin Glyco_hydro_43 PF04616.14 KFH43812.1 - 8.1e-32 110.7 5.2 1.5e-30 106.6 5.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.15 KFH43813.1 - 3.7e-33 114.0 0.1 4.9e-32 110.4 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFH43813.1 - 5.8e-24 85.0 0.0 1.1e-22 80.8 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFH43813.1 - 1.7e-15 57.0 7.4 2.5e-13 49.9 1.0 4.1 3 2 0 3 3 3 2 Multicopper oxidase SnoaL_4 PF13577.6 KFH43814.1 - 2.2e-09 37.5 0.2 2.9e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain TraA PF05513.11 KFH43814.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 TraA Bot1p PF12298.8 KFH43815.1 - 3.9e-49 167.1 6.5 5.6e-49 166.6 6.5 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2312 PF10073.9 KFH43815.1 - 0.022 14.4 1.1 0.063 12.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) HTH_28 PF13518.6 KFH43815.1 - 0.13 12.4 0.9 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Fungal_trans_2 PF11951.8 KFH43816.1 - 3.8e-09 35.8 0.1 5e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH43816.1 - 0.29 11.3 5.5 0.52 10.5 5.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 KFH43818.1 - 5.4e-06 26.5 7.6 5.4e-06 26.5 7.6 2.1 1 1 1 2 2 2 2 Membrane-associating domain FAD_binding_4 PF01565.23 KFH43819.1 - 6.1e-20 71.4 3.9 4.5e-19 68.6 3.9 2.2 1 1 0 1 1 1 1 FAD binding domain PX PF00787.24 KFH43820.1 - 1.5e-24 86.1 0.0 1.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 PX domain Zn_clus PF00172.18 KFH43821.1 - 0.24 11.5 12.3 0.51 10.5 12.3 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.21 KFH43823.1 - 1e-24 87.1 24.0 1.5e-24 86.6 24.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FA_desaturase PF00487.24 KFH43823.1 - 1 9.2 3.9 0.67 9.7 0.2 2.2 1 1 0 2 2 2 0 Fatty acid desaturase Sec2p PF06428.11 KFH43824.1 - 2.4e-27 94.7 15.4 2.4e-27 94.7 15.4 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Med9 PF07544.13 KFH43824.1 - 0.017 15.2 6.8 1.8 8.7 1.8 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KfrA_N PF11740.8 KFH43824.1 - 1.2 9.8 21.1 0.49 11.1 9.0 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF3584 PF12128.8 KFH43824.1 - 5.6 4.3 22.0 8.4 3.8 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 KFH43824.1 - 6.5 6.0 17.9 14 4.9 12.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_S46 PF10459.9 KFH43824.1 - 7.3 5.1 12.8 11 4.5 12.8 1.2 1 0 0 1 1 1 0 Peptidase S46 GH131_N PF18271.1 KFH43825.1 - 9.4e-71 238.5 0.3 7.6e-70 235.5 0.3 1.9 1 1 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain KR PF08659.10 KFH43827.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 KR domain zf-UDP PF14569.6 KFH43828.1 - 0.1 12.7 0.1 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger Pescadillo_N PF06732.11 KFH43829.1 - 3.7e-124 413.7 0.3 8.5e-124 412.5 0.3 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 KFH43829.1 - 2.4e-05 24.6 0.0 8.5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Nop53 PF07767.11 KFH43829.1 - 0.0023 17.4 19.8 0.0023 17.4 19.8 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) BRCT_2 PF16589.5 KFH43829.1 - 0.0062 16.9 0.0 0.03 14.7 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KFH43829.1 - 0.054 12.6 7.7 0.11 11.6 7.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Kelch_1 PF01344.25 KFH43830.1 - 1.6e-42 142.8 14.7 2.7e-08 33.3 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFH43830.1 - 1.5e-39 133.4 11.3 8.7e-07 28.8 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFH43830.1 - 2.5e-36 123.4 17.5 4.5e-07 29.8 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFH43830.1 - 1.7e-34 117.4 13.1 1.9e-06 28.0 0.6 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFH43830.1 - 1.3e-33 114.1 15.8 1.2e-06 28.6 0.0 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFH43830.1 - 4.4e-31 105.7 14.7 4.3e-06 26.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Glyco_tranf_2_3 PF13641.6 KFH43831.1 - 3.2e-24 86.1 0.0 4.6e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFH43831.1 - 2e-08 33.9 0.0 4.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFH43831.1 - 1.7e-07 31.2 0.0 4.3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1270 PF06900.11 KFH43831.1 - 0.22 11.9 2.9 0.54 10.7 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Ribosomal_S17_N PF16205.5 KFH43833.1 - 6.6e-27 93.7 1.2 3.9e-17 62.4 0.2 2.6 3 0 0 3 3 3 2 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFH43833.1 - 8.7e-26 89.8 0.3 1.6e-25 89.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF676 PF05057.14 KFH43834.1 - 4.9e-06 26.2 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFH43834.1 - 0.00017 21.4 0.0 0.00068 19.4 0.0 2.0 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_8 PF06259.12 KFH43834.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KFH43834.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PDZ_1 PF12812.7 KFH43834.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ-like domain Spt4 PF06093.13 KFH43834.1 - 0.15 12.2 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger GWT1 PF06423.12 KFH43835.1 - 6.8e-41 139.9 3.4 2.1e-40 138.3 3.4 1.9 1 0 0 1 1 1 1 GWT1 Prefoldin_3 PF13758.6 KFH43836.1 - 3.9e-32 110.3 1.0 8.3e-32 109.2 1.0 1.6 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KFH43836.1 - 2.2e-19 70.1 0.2 2.2e-19 70.1 0.2 4.9 6 1 0 6 6 6 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.20 KFH43836.1 - 0.014 15.3 1.7 0.41 10.6 0.1 2.8 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.17 KFH43836.1 - 0.024 14.5 1.6 0.53 10.2 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit FliJ PF02050.16 KFH43836.1 - 0.11 12.7 2.8 1.1 9.5 0.1 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein DASH_Spc19 PF08287.11 KFH43836.1 - 0.91 9.4 9.0 1.3 8.9 0.3 3.2 3 0 0 3 3 3 0 Spc19 MerR-DNA-bind PF09278.11 KFH43836.1 - 2.1 8.9 8.1 16 6.1 0.1 4.1 3 0 0 3 3 3 0 MerR, DNA binding MFS_1 PF07690.16 KFH43837.1 - 3.1e-51 174.4 47.8 4e-51 174.0 46.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH43837.1 - 4.9e-23 81.4 11.8 6.2e-23 81.1 9.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH43837.1 - 2e-17 63.2 2.4 2e-17 63.2 2.4 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter Trypan_PARP PF05887.11 KFH43837.1 - 2 8.4 9.0 0.29 11.1 4.9 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Mur_ligase_C PF02875.21 KFH43838.1 - 0.00014 22.1 0.1 0.00072 19.8 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KFH43838.1 - 0.11 12.5 0.0 22 5.0 0.0 2.9 2 1 1 3 3 3 0 Mur ligase middle domain DUF1041 PF06292.17 KFH43839.1 - 0.0077 16.6 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) FH2 PF02181.23 KFH43839.1 - 0.14 11.3 3.5 1.9 7.5 0.7 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Stathmin PF00836.19 KFH43839.1 - 0.14 12.1 8.9 0.12 12.4 6.6 2.0 2 1 0 2 2 2 0 Stathmin family AbiH PF14253.6 KFH43839.1 - 0.2 11.5 0.2 0.27 11.1 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH GCR1_C PF12550.8 KFH43839.1 - 0.28 11.5 2.7 0.66 10.3 2.7 1.7 1 1 0 1 1 1 0 Transcriptional activator of glycolytic enzymes ABC_tran_Xtn PF12848.7 KFH43839.1 - 3 7.9 10.4 8.8 6.4 2.3 2.2 1 1 1 2 2 2 0 ABC transporter Kinesin PF00225.23 KFH43840.1 - 7.9e-110 366.9 0.9 7.9e-110 366.9 0.9 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFH43840.1 - 4e-25 88.5 0.9 2.7e-24 85.8 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 KFH43840.1 - 3.6e-07 30.6 1.4 3.6e-07 30.6 1.4 5.6 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 KFH43840.1 - 1.4 8.8 56.3 0.42 10.4 22.2 4.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TetR_C_24 PF17932.1 KFH43840.1 - 1.6 9.0 9.4 7.6 6.8 0.3 3.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LigD_N PF13298.6 KFH43842.1 - 7.3e-37 125.9 0.0 1.3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Nucleo_P87 PF07267.11 KFH43842.1 - 1.3 7.8 7.8 1.9 7.3 7.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Saw1 PF11561.8 KFH43843.1 - 0.074 12.6 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Pkinase PF00069.25 KFH43844.1 - 8.2e-64 215.5 0.1 9.6e-64 215.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43844.1 - 1.5e-18 67.0 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH43844.1 - 5.3e-09 36.3 0.0 3.6e-06 27.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH43844.1 - 0.0072 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH43844.1 - 0.012 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFH43844.1 - 0.026 13.9 0.2 0.056 12.8 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFH43844.1 - 0.063 12.9 0.1 0.063 12.9 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase Dus PF01207.17 KFH43845.1 - 9.9e-40 136.5 0.0 1.3e-28 100.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KFH43845.1 - 0.0048 16.9 5.7 0.68 10.1 1.1 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KFH43845.1 - 0.098 12.6 3.7 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFH43845.1 - 1.1 10.0 3.8 11 6.8 0.3 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 KFH43845.1 - 1.3 8.9 6.2 1.7 8.5 0.5 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Tom37 PF10568.9 KFH43846.1 - 8.7e-37 126.2 0.2 1.5e-36 125.5 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KFH43846.1 - 1.4e-08 34.3 0.1 4.5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFH43846.1 - 6.9e-07 29.9 0.0 1.9e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Oxygenase-NA PF09859.9 KFH43846.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA GST_C_3 PF14497.6 KFH43846.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain APG6 PF04111.12 KFH43847.1 - 4.7e-71 238.4 0.0 7.1e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KFH43847.1 - 1e-35 123.2 14.5 1.5e-35 122.6 14.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 KFH43847.1 - 0.015 14.0 2.8 0.02 13.5 2.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 KFH43847.1 - 0.017 15.3 10.5 0.057 13.7 10.5 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 KFH43847.1 - 0.066 13.0 12.6 0.1 12.4 12.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2252 PF10009.9 KFH43847.1 - 0.086 11.9 3.9 0.13 11.3 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) HU-DNA_bdg PF14848.6 KFH43847.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 DNA-binding domain ERM PF00769.19 KFH43847.1 - 0.23 11.2 19.3 0.4 10.5 19.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1732 PF08340.11 KFH43847.1 - 0.33 11.0 3.3 0.62 10.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) zf-C4H2 PF10146.9 KFH43847.1 - 0.43 10.9 14.9 0.023 15.0 8.0 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein DUF724 PF05266.14 KFH43847.1 - 1.6 8.5 10.7 2.8 7.7 10.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KFH43847.1 - 3.7 7.6 11.5 7.6 6.6 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSNAXIP1_N PF15739.5 KFH43847.1 - 8.1 6.9 13.2 1 9.8 8.1 2.0 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Ras PF00071.22 KFH43848.1 - 2.3e-58 196.4 0.1 2.7e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH43848.1 - 6.4e-36 123.2 0.2 1e-35 122.6 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH43848.1 - 1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFH43848.1 - 9e-07 28.5 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFH43848.1 - 2e-06 27.9 0.0 4e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH43848.1 - 2e-06 27.5 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH43848.1 - 3.7e-05 23.7 0.8 0.13 12.1 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KFH43848.1 - 0.021 15.2 0.2 0.042 14.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFH43848.1 - 0.077 12.1 0.2 1 8.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KFH43848.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein GbpA_2 PF18416.1 KFH43848.1 - 0.16 12.3 1.2 5.5 7.3 0.0 2.3 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 ABC_tran PF00005.27 KFH43850.1 - 3.4e-49 166.9 0.0 3.6e-29 102.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFH43850.1 - 3.9e-40 138.2 16.0 5.2e-29 101.7 1.4 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KFH43850.1 - 2.3e-08 33.7 0.0 0.0031 17.0 0.0 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFH43850.1 - 0.00035 20.9 0.0 4.8 7.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KFH43850.1 - 0.0013 18.7 0.2 0.89 9.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFH43850.1 - 0.0016 18.8 0.5 0.26 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFH43850.1 - 0.0018 18.3 0.4 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.23 KFH43850.1 - 0.0042 17.1 0.1 4.2 7.4 0.0 3.2 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_21 PF13304.6 KFH43850.1 - 0.0083 16.0 0.0 4.2 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH43850.1 - 0.012 15.4 1.3 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFH43850.1 - 0.014 14.5 0.0 0.83 8.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KFH43850.1 - 0.029 14.5 2.3 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 KFH43850.1 - 0.032 13.5 0.3 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KFH43850.1 - 0.034 14.6 0.2 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFH43850.1 - 0.041 13.5 0.5 1.9 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 KFH43850.1 - 0.13 11.1 0.2 4 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.17 KFH43850.1 - 0.16 11.7 0.0 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFH43850.1 - 0.17 11.5 0.2 7.5 6.2 0.1 2.6 3 0 0 3 3 3 0 AAA domain PIG-U PF06728.13 KFH43852.1 - 1.3e-98 330.6 22.4 1.5e-98 330.3 22.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KFH43852.1 - 0.21 11.3 7.6 0.86 9.3 7.6 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain HIG_1_N PF04588.13 KFH43855.1 - 7.1e-06 26.2 10.5 1.6e-05 25.1 3.5 2.6 2 0 0 2 2 2 2 Hypoxia induced protein conserved region GFA PF04828.14 KFH43856.1 - 1.4e-16 60.6 6.9 1.1e-08 35.3 1.4 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 KFH43857.1 - 1.7e-64 217.7 0.0 2.7e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43857.1 - 1.2e-36 126.4 0.0 2.5e-31 108.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFH43857.1 - 9.1e-07 28.5 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFH43857.1 - 2.7e-05 24.2 0.1 8.6e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH43857.1 - 0.016 14.1 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFH43857.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFH43857.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Mur_ligase_C PF02875.21 KFH43858.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KFH43858.1 - 0.0019 18.2 0.0 0.018 15.0 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Atg14 PF10186.9 KFH43859.1 - 2.4e-73 247.0 0.0 3.4e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 UBN_AB PF14075.6 KFH43859.1 - 0.051 13.3 2.0 0.088 12.5 2.0 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TPD52 PF04201.15 KFH43859.1 - 0.082 12.5 1.4 0.13 11.8 1.4 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Use1 PF09753.9 KFH43859.1 - 0.12 12.1 4.5 0.23 11.1 4.5 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Abhydrolase_5 PF12695.7 KFH43859.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Spc7 PF08317.11 KFH43859.1 - 0.16 10.8 6.0 0.24 10.2 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFH43859.1 - 0.25 11.4 7.3 0.52 10.4 7.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.6 KFH43859.1 - 0.73 9.4 4.7 1.2 8.7 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Esterase_phd PF10503.9 KFH43860.1 - 1.5e-25 90.0 1.1 2.3e-25 89.4 1.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFH43860.1 - 4.5e-10 39.4 2.1 6.2e-10 38.9 2.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFH43860.1 - 0.0029 17.3 1.0 0.0066 16.1 1.0 1.5 1 1 0 1 1 1 1 Putative esterase Spc7_N PF15402.6 KFH43861.1 - 2.1e-190 635.3 75.5 5.7e-186 620.6 75.5 3.1 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KFH43861.1 - 4e-125 416.8 4.2 7e-125 416.0 4.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KFH43861.1 - 7.4e-21 74.0 0.4 1.3e-20 73.2 0.4 1.4 1 0 0 1 1 1 1 Spc7_C2 TMF_DNA_bd PF12329.8 KFH43861.1 - 0.13 12.3 4.2 0.58 10.2 4.2 2.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sec34 PF04136.15 KFH43861.1 - 0.14 12.1 3.0 0.7 9.8 0.5 2.4 2 0 0 2 2 2 0 Sec34-like family GAS PF13851.6 KFH43861.1 - 0.14 11.4 5.2 0.35 10.2 5.2 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RRN9 PF10680.9 KFH43862.1 - 4.5e-14 52.5 0.1 4.5e-14 52.5 0.1 2.7 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 KFH43862.1 - 0.23 12.0 0.4 0.64 10.6 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type tRNA-synt_1 PF00133.22 KFH43863.1 - 1e-157 526.0 0.0 1.5e-157 525.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFH43863.1 - 7.9e-22 77.5 0.1 5.2e-14 51.8 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFH43863.1 - 2.1e-18 66.7 0.0 3.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KFH43863.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 KFH43863.1 - 0.11 12.4 2.3 0.24 11.3 2.3 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 KFH43863.1 - 0.11 11.9 0.3 11 5.3 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF3807 PF12720.7 KFH43864.1 - 1.4e-38 133.0 0.4 2.1e-38 132.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) WD40 PF00400.32 KFH43865.1 - 2.7e-16 59.6 15.3 0.0043 17.9 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43865.1 - 2e-15 56.8 0.0 6.2e-06 26.4 0.0 5.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH43865.1 - 0.00021 21.2 0.1 0.049 13.5 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFH43865.1 - 0.027 13.4 0.0 16 4.3 0.0 3.7 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFH43865.1 - 0.034 14.1 5.6 5.4 7.1 1.0 4.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Peroxin-13_N PF04088.13 KFH43866.1 - 6.8e-51 172.4 0.1 1.2e-50 171.6 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KFH43866.1 - 2.7e-09 36.6 0.0 4.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFH43866.1 - 1.1e-07 31.3 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH43866.1 - 4.1e-07 29.8 0.1 7.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mitofilin PF09731.9 KFH43867.1 - 4.9e-141 471.6 24.2 3.8e-123 412.5 18.2 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Cor1 PF04803.12 KFH43867.1 - 0.18 12.0 10.7 0.36 11.0 10.7 1.5 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region COX1 PF00115.20 KFH43867.1 - 0.3 9.9 0.0 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I PTRF_SDPR PF15237.6 KFH43867.1 - 0.47 10.0 12.4 52 3.3 12.4 2.5 1 1 0 1 1 1 0 PTRF/SDPR family DUF4449 PF14613.6 KFH43867.1 - 3.9 7.6 10.4 26 4.9 10.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) Scm3 PF10384.9 KFH43868.1 - 1.9e-18 65.9 0.0 3.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Syja_N PF02383.18 KFH43869.1 - 1.6e-87 293.8 0.1 2.1e-87 293.5 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain AAA PF00004.29 KFH43870.1 - 7.7e-12 45.8 0.0 1.6e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH43870.1 - 0.0007 20.0 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFH43870.1 - 0.015 15.5 0.2 0.098 12.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KFH43870.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KFH43870.1 - 0.13 12.1 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 KFH43870.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain HSP20 PF00011.21 KFH43871.1 - 1.6e-17 63.5 0.1 2.6e-11 43.6 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFH43871.1 - 0.0007 19.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 2 HSP20-like domain found in ArsA dCMP_cyt_deam_1 PF00383.23 KFH43872.1 - 8.7e-26 89.8 0.9 1.3e-25 89.2 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFH43872.1 - 1.4e-09 37.9 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KFH43872.1 - 3.7e-05 24.3 0.1 0.021 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain CoaE PF01121.20 KFH43872.1 - 0.034 13.8 0.1 0.092 12.4 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.6 KFH43872.1 - 0.3 11.2 1.8 4.2 7.5 1.8 2.3 1 1 0 1 1 1 0 AAA domain DUF4142 PF13628.6 KFH43873.1 - 2.9 8.1 6.4 15 5.8 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) PPR_2 PF13041.6 KFH43874.1 - 9.3e-06 25.7 0.0 0.017 15.3 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KFH43874.1 - 9.7e-06 25.6 0.0 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KFH43874.1 - 0.057 13.7 0.1 3 8.3 0.0 2.7 2 0 0 2 2 2 0 PPR repeat FAD_binding_4 PF01565.23 KFH43875.1 - 6.7e-24 84.2 0.8 1.2e-23 83.4 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH43875.1 - 0.0023 18.0 1.2 0.0053 16.8 1.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like He_PIG PF05345.12 KFH43876.1 - 2.5e-10 40.4 9.7 0.00061 19.9 0.3 4.9 5 0 0 5 5 5 3 Putative Ig domain TMEM154 PF15102.6 KFH43876.1 - 7.8e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family zf_Hakai PF18408.1 KFH43876.1 - 0.016 14.9 0.7 0.031 14.0 0.7 1.4 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain DUF4690 PF15756.5 KFH43876.1 - 0.034 14.7 0.4 0.034 14.7 0.4 2.9 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF4448 PF14610.6 KFH43876.1 - 0.048 13.4 0.0 0.18 11.6 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) AJAP1_PANP_C PF15298.6 KFH43876.1 - 0.088 13.0 0.4 0.2 11.8 0.4 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus RSN1_TM PF13967.6 KFH43876.1 - 0.22 11.3 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport SKG6 PF08693.10 KFH43876.1 - 0.22 11.0 4.2 0.43 10.0 4.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Hum_adeno_E3A PF05393.11 KFH43876.1 - 0.4 10.7 1.1 0.93 9.5 1.1 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF3394 PF11874.8 KFH43876.1 - 0.5 10.0 1.1 2.9 7.5 1.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) Aconitase PF00330.20 KFH43877.1 - 1.5e-133 446.2 0.0 2.3e-133 445.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFH43877.1 - 1.3e-40 138.7 0.0 2.1e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DPBB_1 PF03330.18 KFH43878.1 - 0.003 17.8 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase VIR_N PF15912.5 KFH43878.1 - 0.79 9.3 14.8 1.2 8.7 14.8 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal 4HBT_2 PF13279.6 KFH43879.1 - 0.00063 20.2 0.0 0.00097 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3662 PF12401.8 KFH43880.1 - 0.082 13.3 0.0 0.087 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Amino_oxidase PF01593.24 KFH43881.1 - 8.7e-52 176.9 0.0 1.7e-51 176.0 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH43881.1 - 1.8e-15 56.9 0.0 4.2e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH43881.1 - 2.2e-07 30.4 0.1 6.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH43881.1 - 1.8e-06 28.1 0.0 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KFH43881.1 - 8.2e-05 21.5 0.0 0.0031 16.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KFH43881.1 - 0.00014 21.5 0.9 0.0065 16.1 0.5 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFH43881.1 - 0.00027 21.4 0.0 0.00069 20.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH43881.1 - 0.00087 18.5 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KFH43881.1 - 0.0039 16.5 0.1 0.0058 15.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KFH43881.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KFH43881.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFH43881.1 - 0.06 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KFH43881.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFH43881.1 - 0.083 12.1 0.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_8 PF01501.20 KFH43882.1 - 3.1e-14 53.2 0.0 7e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 SAE2 PF08573.10 KFH43883.1 - 3.2e-39 134.5 0.4 3.2e-39 134.5 0.4 2.8 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus LPD39 PF18858.1 KFH43883.1 - 0.001 19.2 1.1 0.001 19.2 1.1 1.7 2 0 0 2 2 2 1 Large polyvalent protein associated domain 39 Mito_carr PF00153.27 KFH43884.1 - 5.4e-64 212.2 2.7 4.2e-22 77.9 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KFH43885.1 - 6.3e-33 114.1 0.3 9.2e-33 113.6 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KFH43885.1 - 2.2e-18 66.2 0.0 4.9e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KFH43885.1 - 5e-16 58.7 0.1 8.6e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFH43885.1 - 1.3e-06 29.1 0.0 3.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH43885.1 - 3.6e-06 27.3 0.0 7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 KFH43886.1 - 1.1e-41 143.0 0.0 1.2e-39 136.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43886.1 - 2.5e-25 89.2 0.0 4.5e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH43886.1 - 0.16 11.3 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ketoacyl-synt PF00109.26 KFH43887.1 - 3.6e-75 252.8 0.0 7.8e-75 251.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFH43887.1 - 1.9e-51 175.5 1.0 3.6e-51 174.6 1.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH43887.1 - 2e-51 174.5 0.0 4.9e-51 173.2 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH43887.1 - 4.3e-48 164.1 0.0 9e-48 163.0 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFH43887.1 - 2e-37 127.8 0.1 2.4e-36 124.3 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFH43887.1 - 7.6e-17 61.8 0.0 2.3e-16 60.2 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFH43887.1 - 3.3e-10 39.8 0.1 1.5e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KFH43887.1 - 9.2e-09 35.4 0.1 4.2e-08 33.2 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SAT PF16073.5 KFH43887.1 - 0.00038 20.3 1.0 0.0062 16.3 1.4 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_zinc_N_2 PF13602.6 KFH43887.1 - 0.0046 18.0 0.0 0.017 16.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KFH43887.1 - 0.0051 17.1 0.0 0.02 15.3 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFH43887.1 - 0.018 14.4 1.3 0.065 12.6 0.3 2.3 3 0 0 3 3 3 0 Thiolase, N-terminal domain Epimerase PF01370.21 KFH43887.1 - 0.041 13.3 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UPF0181 PF03701.14 KFH43887.1 - 0.15 11.7 0.1 0.47 10.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Zn_clus PF00172.18 KFH43888.1 - 7.8e-10 38.7 8.0 2.1e-09 37.4 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KFH43890.1 - 1.1e-19 70.4 10.4 0.00027 21.7 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43890.1 - 3.1e-07 30.6 0.0 0.0038 17.5 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFH43890.1 - 7.7e-05 22.2 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KFH43890.1 - 0.00026 20.1 1.2 0.21 10.5 0.0 3.1 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KFH43891.1 - 9.8e-42 141.4 1.7 7.7e-12 45.6 0.0 7.8 5 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH43891.1 - 1.2e-33 115.0 4.7 2.4e-08 34.3 0.0 10.6 7 3 4 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH43891.1 - 3.7e-30 100.6 3.3 5.9e-05 23.2 0.0 13.3 14 1 1 15 15 15 6 Ankyrin repeat Ank PF00023.30 KFH43891.1 - 5.7e-27 92.9 19.6 5.5e-05 23.4 0.2 12.4 13 1 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 KFH43891.1 - 1.4e-15 57.1 13.0 0.00015 22.0 0.2 10.1 8 3 4 12 12 12 5 Ankyrin repeats (many copies) DUF4147 PF13660.6 KFH43891.1 - 0.18 11.3 1.3 17 4.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) adh_short_C2 PF13561.6 KFH43893.1 - 7.7e-52 176.2 0.0 9.6e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH43893.1 - 1.5e-47 161.6 0.0 1.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH43893.1 - 5.9e-07 29.6 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain PALP PF00291.25 KFH43893.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2974 PF11187.8 KFH43893.1 - 0.057 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF829 PF05705.14 KFH43894.1 - 2.9e-43 148.5 0.0 4.3e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Complex1_LYR_2 PF13233.6 KFH43896.1 - 6.3e-22 78.1 0.0 7.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RraA-like PF03737.15 KFH43897.1 - 2.4e-35 121.9 0.0 3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Adaptin_binding PF10199.9 KFH43898.1 - 0.12 13.0 2.2 0.15 12.7 0.1 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CFEM PF05730.11 KFH43899.1 - 1.7e-09 37.6 8.7 2.8e-09 36.9 8.7 1.3 1 0 0 1 1 1 1 CFEM domain Herpes_pp85 PF04637.12 KFH43899.1 - 0.006 15.1 2.0 0.007 14.8 2.0 1.0 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UL73_N PF12522.8 KFH43899.1 - 1.1 9.1 10.3 2.4 8.0 10.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal PP2C PF00481.21 KFH43900.1 - 9.6e-84 281.0 0.0 1.5e-83 280.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFH43900.1 - 0.043 13.7 0.2 0.43 10.5 0.0 2.4 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CDC45 PF02724.14 KFH43900.1 - 0.14 10.5 9.1 0.18 10.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.24 KFH43901.1 - 8.4e-50 170.3 3.5 9.9e-50 170.1 3.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFH43901.1 - 0.00033 20.0 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH43901.1 - 0.001 19.2 0.2 0.0022 18.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFH43901.1 - 0.0011 18.3 0.4 0.0017 17.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFH43901.1 - 0.0012 17.7 0.0 0.053 12.2 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFH43901.1 - 0.0027 16.9 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFH43901.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KFH43901.1 - 0.012 14.9 0.3 0.045 13.0 0.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH43901.1 - 0.032 13.6 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFH43901.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFH43901.1 - 0.25 11.3 1.6 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding E1-E2_ATPase PF00122.20 KFH43902.1 - 3.9e-35 121.0 21.1 5.4e-26 91.2 0.3 4.5 5 1 1 6 6 6 3 E1-E2 ATPase Hydrolase PF00702.26 KFH43902.1 - 1.3e-16 61.6 0.0 2.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH43902.1 - 2.4e-10 39.9 0.4 1.1e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH43902.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH43902.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CENP-B_dimeris PF09026.10 KFH43902.1 - 0.045 14.1 1.2 0.1 13.0 1.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GNVR PF13807.6 KFH43902.1 - 0.09 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Methyltransf_16 PF10294.9 KFH43903.1 - 2.9e-41 141.1 0.0 3.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KFH43903.1 - 0.0091 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH43903.1 - 0.047 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF1712 PF08217.11 KFH43904.1 - 1.7e-10 40.0 0.0 1.7e-09 36.8 0.0 2.3 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) DUF4106 PF13388.6 KFH43904.1 - 2.3 7.3 13.4 3.8 6.6 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) NmrA PF05368.13 KFH43905.1 - 6.7e-16 58.6 0.0 9.1e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH43905.1 - 3.6e-13 49.8 0.0 6.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFH43905.1 - 4.4e-08 33.4 0.1 7.1e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFH43905.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFH43905.1 - 0.00042 20.7 0.3 0.0013 19.2 0.3 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFH43905.1 - 0.001 19.6 0.2 0.002 18.6 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KFH43905.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFH43905.1 - 0.021 14.0 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein ApbA PF02558.16 KFH43905.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AbiEi_4 PF13338.6 KFH43905.1 - 0.16 12.2 0.0 0.78 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin ATG2_CAD PF13329.6 KFH43906.1 - 3.4e-54 182.8 0.1 6.8e-54 181.8 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KFH43906.1 - 2.6e-27 95.0 0.4 3.9e-26 91.2 0.0 3.0 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 KFH43906.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KFH43906.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal UCH PF00443.29 KFH43907.1 - 1.3e-45 156.0 0.0 2.3e-45 155.1 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH43907.1 - 2.9e-10 40.2 0.0 2.5e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.7 KFH43907.1 - 0.22 11.7 0.8 0.54 10.4 0.8 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain UCR_14kD PF02271.16 KFH43908.1 - 9.3e-44 147.5 2.3 1.1e-43 147.3 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 KFH43908.1 - 0.014 15.2 0.3 0.016 15.0 0.3 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family ASL_C PF08328.11 KFH43908.1 - 0.059 13.5 0.2 0.075 13.1 0.2 1.4 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF3500 PF12006.8 KFH43908.1 - 0.091 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) LRR19-TM PF15176.6 KFH43908.1 - 0.12 12.4 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain zf-CCHC PF00098.23 KFH43909.1 - 5.2e-27 92.7 52.0 5.2e-08 32.6 2.6 6.1 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 KFH43909.1 - 5.2e-05 23.1 25.4 0.1 12.6 1.6 4.5 3 2 1 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFH43909.1 - 0.00018 21.2 28.8 0.05 13.3 0.2 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.6 KFH43909.1 - 0.0016 18.1 19.7 0.048 13.4 1.2 3.8 3 1 0 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KFH43909.1 - 0.063 13.1 39.0 0.52 10.2 0.9 5.4 2 1 2 4 4 4 0 Zinc knuckle Keratin_2_head PF16208.5 KFH43909.1 - 1.2 9.3 21.3 1.5 8.9 21.3 1.3 1 0 0 1 1 1 0 Keratin type II head bZIP_1 PF00170.21 KFH43910.1 - 7e-08 32.4 6.3 7e-08 32.4 6.3 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFH43910.1 - 0.00034 20.6 6.5 0.00034 20.6 6.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper SNAPc19 PF15497.6 KFH43910.1 - 0.0004 20.8 1.7 0.00064 20.1 0.2 2.0 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 bZIP_Maf PF03131.17 KFH43910.1 - 0.18 12.4 7.7 0.07 13.7 4.5 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 KFH43910.1 - 0.54 10.1 2.5 1.1 9.0 2.5 1.6 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 KFH43910.1 - 2.6 6.5 7.9 3.2 6.2 7.9 1.0 1 0 0 1 1 1 0 Macoilin family Abhydrolase_6 PF12697.7 KFH43911.1 - 1.5e-14 55.1 2.8 7.5e-14 52.9 2.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH43911.1 - 1.7e-07 31.2 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH43911.1 - 5.8e-05 22.5 0.1 0.13 11.5 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF3089 PF11288.8 KFH43911.1 - 0.028 14.0 0.4 0.057 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) FSH1 PF03959.13 KFH43911.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ADH_N PF08240.12 KFH43913.1 - 4.6e-23 81.2 4.6 7.4e-23 80.5 4.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43913.1 - 5.6e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43913.1 - 1.1e-05 26.5 0.0 1.8e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFH43913.1 - 0.0093 15.3 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HAD_2 PF13419.6 KFH43914.1 - 5.3e-09 36.4 0.0 9.1e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH43914.1 - 0.00012 22.4 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MNNL PF07657.13 KFH43915.1 - 0.075 13.1 2.0 0.14 12.2 2.0 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand Cupin_1 PF00190.22 KFH43916.1 - 1.2e-07 31.4 0.2 1.6e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFH43916.1 - 5.7e-07 29.2 0.9 1e-06 28.3 0.9 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KFH43916.1 - 0.0052 16.5 0.1 0.0069 16.1 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFH43916.1 - 0.0096 15.8 0.2 0.015 15.2 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DEAD PF00270.29 KFH43917.1 - 2.1e-49 167.7 0.0 4.6e-48 163.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH43917.1 - 4.2e-32 110.8 0.1 1.1e-31 109.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH43917.1 - 3.9e-05 23.7 0.0 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFH43917.1 - 0.001 17.9 0.0 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C_2 PF13307.6 KFH43917.1 - 0.038 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 KFH43917.1 - 0.038 14.3 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 KFH43917.1 - 0.042 13.1 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2443 PF10398.9 KFH43917.1 - 0.043 13.9 0.5 0.093 12.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF5335 PF17269.2 KFH43917.1 - 0.089 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) His_Phos_1 PF00300.22 KFH43918.1 - 9.1e-24 84.2 0.1 1.1e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) tRNA-synt_1c PF00749.21 KFH43919.1 - 1.2e-85 287.2 0.0 1.7e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ANAPC15 PF15243.6 KFH43920.1 - 1.4 9.4 6.1 2.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 PP2C PF00481.21 KFH43922.1 - 6.8e-59 199.6 0.6 1.8e-48 165.4 0.5 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C Ribosomal_60s PF00428.19 KFH43922.1 - 0.095 13.3 15.6 0.22 12.1 6.5 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DnaJ_C PF01556.18 KFH43923.1 - 2.1e-35 122.0 0.0 3.2e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFH43923.1 - 4.7e-24 84.3 4.3 8.3e-24 83.5 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFH43923.1 - 8.2e-14 51.7 17.5 1.5e-13 50.9 17.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFH43923.1 - 0.0058 16.6 11.2 0.33 10.9 1.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFH43923.1 - 0.15 12.1 6.4 2.3 8.3 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KFH43923.1 - 3 7.1 4.4 5.4 6.2 0.2 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1356) PDH PF02153.17 KFH43924.1 - 9.4e-16 57.6 0.0 1.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KFH43924.1 - 1.4e-06 28.8 0.0 3.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFH43924.1 - 5.1e-06 26.8 0.0 9.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFH43924.1 - 7e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFH43924.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KFH43924.1 - 0.0075 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KFH43924.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFH43924.1 - 0.037 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HMA PF00403.26 KFH43925.1 - 8.9e-11 42.1 0.1 1.4e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KFH43925.1 - 7.6e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Glyco_hydro_47 PF01532.20 KFH43926.1 - 3.2e-163 543.9 0.0 3.7e-163 543.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 KFH43926.1 - 0.11 11.7 0.0 8.6 5.5 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) SH3_1 PF00018.28 KFH43927.1 - 3.1e-05 23.5 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH43927.1 - 0.041 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Uricase PF01014.18 KFH43928.1 - 2.7e-80 267.0 1.6 1.1e-42 145.3 0.5 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L32e PF01655.18 KFH43931.1 - 3.7e-49 165.6 0.4 3.7e-49 165.6 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L32 Rad9 PF04139.13 KFH43932.1 - 1.3e-42 146.0 0.0 1.6e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 AMP-binding PF00501.28 KFH43933.1 - 2.1e-48 165.0 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH43933.1 - 1.5e-06 29.1 0.1 5.3e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFH43933.1 - 2e-05 24.4 1.7 0.00016 21.5 0.1 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Ran_BP1 PF00638.18 KFH43934.1 - 1.2e-49 167.6 0.7 2e-49 166.9 0.7 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KFH43934.1 - 0.0054 16.6 0.1 0.017 15.1 0.1 1.7 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.10 KFH43934.1 - 0.015 14.7 17.0 0.021 14.2 17.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PHD20L1_u1 PF16660.5 KFH43934.1 - 0.22 12.3 2.9 0.4 11.4 2.9 1.4 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 EAP30 PF04157.16 KFH43935.1 - 9.9e-75 250.8 0.0 1.1e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Zn_clus PF00172.18 KFH43936.1 - 5.5e-07 29.6 12.0 8.9e-07 28.9 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chitin_synth_2 PF03142.15 KFH43937.1 - 1e-39 136.6 6.3 1.1e-31 110.1 3.2 2.2 1 1 1 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 KFH43937.1 - 1.1e-07 31.8 0.0 0.0002 21.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KFH43937.1 - 3.8e-06 26.9 8.8 3.8e-06 26.9 8.8 3.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 CHD5 PF04420.14 KFH43937.1 - 0.037 13.9 0.3 0.087 12.7 0.3 1.6 1 0 0 1 1 1 0 CHD5-like protein Wzy_C PF04932.15 KFH43937.1 - 0.1 12.2 2.3 2.7 7.6 0.9 2.8 3 0 0 3 3 3 0 O-Antigen ligase Phosducin PF02114.16 KFH43938.1 - 2.6e-07 29.9 0.0 7.2e-06 25.1 0.0 2.2 1 1 1 2 2 2 2 Phosducin AAR2 PF05282.11 KFH43939.1 - 5.6e-46 157.6 0.0 1.2e-45 156.5 0.0 1.5 1 1 0 1 1 1 1 AAR2 protein Tom22 PF04281.13 KFH43940.1 - 2.6e-51 173.0 0.0 3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Aminotran_1_2 PF00155.21 KFH43941.1 - 3.3e-55 187.7 0.0 4.6e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFH43941.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Phos_pyr_kin PF08543.12 KFH43942.1 - 7.3e-84 281.0 0.1 9.9e-84 280.6 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KFH43942.1 - 9e-45 153.1 0.3 1.3e-44 152.5 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KFH43942.1 - 2.7e-06 26.9 0.0 1.7e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HNF-1B_C PF04812.13 KFH43942.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus UDPG_MGDP_dh PF00984.19 KFH43943.1 - 9e-20 70.7 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KFH43943.1 - 7.6e-16 58.2 0.0 9.1e-14 51.5 0.0 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KFH43943.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KFH43943.1 - 0.015 15.6 0.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_C PF03720.15 KFH43943.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ELFV_dehydrog PF00208.21 KFH43944.1 - 4.7e-64 216.4 0.0 7.3e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KFH43944.1 - 2e-20 72.1 0.0 1.7e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KFH43944.1 - 0.0029 17.5 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Mrr_N PF14338.6 KFH43944.1 - 0.053 13.6 0.1 1.7 8.8 0.2 3.1 3 0 0 3 3 3 0 Mrr N-terminal domain Dynamin_N PF00350.23 KFH43946.1 - 6.2e-18 65.4 0.7 1.2e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFH43946.1 - 4.3e-10 39.7 0.0 2.8e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH43946.1 - 4e-06 26.5 0.0 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH43946.1 - 0.0058 16.5 0.5 5.4 6.9 0.0 3.1 2 1 1 3 3 3 2 RsgA GTPase TsaE PF02367.17 KFH43946.1 - 0.018 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1184 PF06683.11 KFH43946.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) Sigma54_activat PF00158.26 KFH43946.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 KFH43946.1 - 0.035 13.7 0.5 0.31 10.6 0.5 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFH43946.1 - 0.035 14.6 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain Prominin PF05478.11 KFH43946.1 - 0.053 11.5 0.4 0.097 10.6 0.4 1.3 1 0 0 1 1 1 0 Prominin Roc PF08477.13 KFH43946.1 - 0.082 13.1 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFH43946.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF3446 PF11928.8 KFH43946.1 - 0.22 11.9 11.7 0.27 11.5 0.1 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain TPR_1 PF00515.28 KFH43947.1 - 9.1e-17 60.1 2.4 6.5e-08 32.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH43947.1 - 9.9e-16 56.5 3.0 4.2e-06 26.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFH43947.1 - 2.1e-11 43.9 0.9 2.8e-07 30.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH43947.1 - 2.1e-10 39.9 0.7 1.2e-05 25.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH43947.1 - 3.4e-09 36.8 0.2 0.16 12.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFH43947.1 - 7e-08 32.0 0.6 7.6e-06 25.6 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFH43947.1 - 3.4e-07 29.8 1.9 3.6e-05 23.3 0.1 3.8 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 KFH43947.1 - 2.7e-06 27.2 0.1 4.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.6 KFH43947.1 - 4.9e-05 23.9 3.0 0.0066 17.1 0.1 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFH43947.1 - 8.2e-05 22.7 0.2 0.15 12.2 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFH43947.1 - 0.0012 19.0 0.0 1.6 9.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFH43947.1 - 0.0025 17.6 1.4 0.22 11.5 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH43947.1 - 0.0028 18.3 1.0 0.31 12.0 0.0 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFH43947.1 - 0.0088 16.6 0.2 47 5.0 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 KFH43948.1 - 2.6e-23 82.4 19.3 7.4e-11 42.5 0.1 7.1 6 1 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFH43948.1 - 1.1e-17 63.3 23.6 9.2e-07 28.5 2.1 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L13 PF00572.18 KFH43949.1 - 2.8e-44 150.4 0.0 6.9e-44 149.1 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 KFH43951.1 - 3.9e-34 117.8 0.2 4.4e-34 117.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RICTOR_N PF14664.6 KFH43952.1 - 1.9e-135 451.7 0.1 6.2e-135 450.0 0.0 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KFH43952.1 - 4.3e-40 135.7 0.0 1.7e-37 127.3 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KFH43952.1 - 6.5e-37 126.2 0.0 4.2e-35 120.4 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KFH43952.1 - 1.1e-28 99.3 0.1 1e-26 92.9 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KFH43952.1 - 5.2e-14 52.1 11.7 1.1e-13 51.0 11.7 1.5 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 KFH43952.1 - 0.012 15.8 7.3 0.035 14.3 7.3 1.8 1 0 0 1 1 1 0 Up-regulated During Septation DNA_pol_phi PF04931.13 KFH43952.1 - 0.33 9.0 13.3 0.7 7.9 13.3 1.5 1 0 0 1 1 1 0 DNA polymerase phi Lzipper-MIP1 PF14389.6 KFH43952.1 - 0.4 11.0 2.6 1.3 9.3 2.6 1.9 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF724 PF05266.14 KFH43952.1 - 1.2 8.9 4.1 2.9 7.7 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFH43952.1 - 1.3 9.7 4.2 0.96 10.1 1.7 2.3 2 0 0 2 2 1 0 SlyX FmiP_Thoc5 PF09766.9 KFH43952.1 - 1.4 8.2 6.6 0.36 10.1 1.3 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 TFIIA PF03153.13 KFH43952.1 - 2.9 7.8 6.0 0.63 10.0 1.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.13 KFH43952.1 - 4.9 6.0 8.7 0.081 11.9 1.0 1.7 2 0 0 2 2 2 0 Paf1 WD40 PF00400.32 KFH43953.1 - 2.5e-37 126.2 19.8 3.6e-07 30.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43953.1 - 1.6e-14 54.0 0.0 0.00038 20.7 0.1 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH43953.1 - 3.7e-05 22.9 0.2 0.39 9.6 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFH43953.1 - 0.00023 21.1 0.0 0.24 11.2 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFH43953.1 - 0.0054 16.1 0.0 0.48 9.7 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Glyco_hydro_18 PF00704.28 KFH43954.1 - 2e-63 215.0 0.0 2.3e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 KFH43954.1 - 0.071 13.5 0.0 0.25 11.7 0.0 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family YEATS PF03366.16 KFH43955.1 - 5.9e-18 64.6 0.0 1.4e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFH43955.1 - 0.00048 20.2 5.0 0.0012 19.0 2.2 2.5 2 1 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Spt20 PF12090.8 KFH43956.1 - 2.1 7.9 13.9 0.13 11.9 8.7 1.6 2 0 0 2 2 2 0 Spt20 family Snf7 PF03357.21 KFH43957.1 - 1.5e-35 122.3 20.6 2e-35 122.0 20.0 1.4 2 0 0 2 2 2 1 Snf7 RHH_8 PF17723.1 KFH43957.1 - 0.12 12.6 3.3 0.25 11.5 0.3 2.5 1 1 2 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family Ist1 PF03398.14 KFH43957.1 - 0.17 11.8 7.9 0.25 11.3 7.9 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.12 KFH43957.1 - 0.96 9.0 16.3 1.7 8.2 5.3 2.1 1 1 0 2 2 2 0 PspA/IM30 family Cofilin_ADF PF00241.20 KFH43958.1 - 6.9e-05 22.6 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mpv17_PMP22 PF04117.12 KFH43959.1 - 1e-09 38.4 4.8 1.4e-09 38.0 3.4 1.9 1 1 1 2 2 2 1 Mpv17 / PMP22 family Pyr_redox_2 PF07992.14 KFH43960.1 - 1.2e-53 182.2 0.1 1.6e-53 181.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH43960.1 - 5.1e-13 49.4 0.0 5.8e-11 42.8 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH43960.1 - 0.00016 21.0 0.4 0.094 11.9 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFH43960.1 - 0.0019 18.6 0.1 0.91 10.0 0.0 2.8 3 0 0 3 3 3 2 Putative NAD(P)-binding Phage_TAC_11 PF11836.8 KFH43960.1 - 0.099 12.8 0.0 0.77 9.9 0.1 2.3 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 KR PF08659.10 KFH43961.1 - 4.6e-61 205.9 0.3 4.6e-61 205.9 0.3 2.6 3 0 0 3 3 3 1 KR domain ketoacyl-synt PF00109.26 KFH43961.1 - 5.7e-59 199.7 0.2 1.3e-58 198.6 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFH43961.1 - 1.2e-51 175.8 0.0 2e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH43961.1 - 1.8e-47 162.4 0.0 3.2e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH43961.1 - 1e-37 128.8 0.1 2.6e-37 127.4 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH43961.1 - 8.8e-18 64.9 0.0 4e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KFH43961.1 - 3.4e-17 62.6 0.1 2.3e-16 59.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43961.1 - 2.1e-14 54.7 0.0 2.2e-12 48.2 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KFH43961.1 - 2.2e-13 50.4 0.0 7.5e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH43961.1 - 5.6e-13 49.4 0.0 2.1e-12 47.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH43961.1 - 3e-12 47.0 0.0 8.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KFH43961.1 - 3.4e-11 43.6 0.0 1.2e-10 41.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH43961.1 - 7.5e-11 41.8 2.6 5.7e-10 39.0 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 KFH43961.1 - 1.6e-08 34.4 0.2 4.7e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KFH43961.1 - 3.7e-08 33.3 0.0 3.3e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KFH43961.1 - 8.2e-05 22.9 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFH43961.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFH43961.1 - 0.0087 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KFH43961.1 - 0.029 13.8 0.2 0.08 12.3 0.2 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFH43961.1 - 0.052 13.4 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPOC PF07744.13 KFH43962.1 - 6.5e-26 91.1 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KFH43962.1 - 1.3e-17 64.2 0.1 3.5e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFH43962.1 - 9.6e-09 35.0 9.7 1.8e-08 34.1 9.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KFH43962.1 - 8.4 6.6 10.3 23 5.2 10.3 1.8 1 0 0 1 1 1 0 PHD-finger ADH_N PF08240.12 KFH43963.1 - 1.1e-23 83.2 0.2 2.3e-23 82.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH43963.1 - 2.9e-19 69.3 0.0 4.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH43963.1 - 0.0078 17.3 0.0 0.015 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFH43963.1 - 0.024 14.0 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFH43963.1 - 0.03 13.6 0.7 0.046 13.0 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFH43963.1 - 0.07 13.0 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KFH43964.1 - 5.5e-15 55.1 0.0 9.7e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SP_C-Propep PF08999.10 KFH43964.1 - 0.06 13.1 2.4 0.13 12.0 2.4 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide zf-C2H2_jaz PF12171.8 KFH43965.1 - 0.00074 19.7 0.2 0.0014 18.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3439 PF11921.8 KFH43965.1 - 0.81 9.7 7.1 2.1 8.3 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) dsRBD2 PF17842.1 KFH43965.1 - 1.5 9.0 4.3 0.84 9.8 0.1 2.4 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 SUIM_assoc PF16619.5 KFH43965.1 - 4.9 7.3 13.7 41 4.3 13.7 2.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LAMTOR PF15454.6 KFH43967.1 - 3.9e-06 27.4 0.0 6.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Sugar_tr PF00083.24 KFH43968.1 - 4.6e-86 289.5 12.4 5.3e-86 289.3 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH43968.1 - 3.2e-31 108.5 16.0 4.4e-31 108.1 16.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH43968.1 - 3.2e-08 32.5 4.1 6.5e-08 31.4 2.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFH43968.1 - 1.2e-05 24.1 0.3 1.2e-05 24.1 0.3 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFH43968.1 - 0.00043 19.3 1.1 0.021 13.7 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family PTR2 PF00854.21 KFH43968.1 - 0.0019 17.1 0.6 0.0019 17.1 0.6 2.4 2 1 0 2 2 2 1 POT family Cas1_AcylT PF07779.12 KFH43969.1 - 2.2e-121 406.1 3.9 3.1e-121 405.6 3.9 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KFH43969.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF5507 PF17612.2 KFH43969.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5507) SLT PF01464.20 KFH43970.1 - 0.022 14.4 0.4 0.085 12.5 0.4 1.9 1 1 0 1 1 1 0 Transglycosylase SLT domain SLT_2 PF13406.6 KFH43970.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Hydrophobin_2 PF06766.11 KFH43971.1 - 4.1e-27 93.9 10.8 5.1e-27 93.6 10.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin K_oxygenase PF13434.6 KFH43972.1 - 1.3e-110 369.8 0.0 1.5e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFH43972.1 - 7.8e-07 28.6 0.0 4e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH43972.1 - 9.5e-07 28.3 0.0 0.00015 21.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH43972.1 - 0.00058 19.9 0.1 0.048 13.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Glyco_hydro_43 PF04616.14 KFH43973.1 - 0.0028 17.0 0.3 0.0056 16.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sortilin-Vps10 PF15902.5 KFH43973.1 - 0.02 13.7 0.7 0.91 8.2 0.0 2.8 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFH43973.1 - 0.031 14.2 0.2 5 7.5 0.1 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Trypan_PARP PF05887.11 KFH43974.1 - 0.074 13.0 2.8 0.13 12.2 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NACHT_N PF17100.5 KFH43975.1 - 8.3e-33 114.1 0.0 1.2e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Glyco_transf_15 PF01793.16 KFH43975.1 - 2.8e-32 112.3 0.0 3.5e-16 59.4 0.0 3.2 2 1 1 3 3 3 3 Glycolipid 2-alpha-mannosyltransferase AMP-binding PF00501.28 KFH43976.1 - 8.6e-217 719.7 0.0 9e-77 258.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFH43976.1 - 1.4e-163 544.9 0.0 2.1e-31 109.1 0.0 7.3 7 0 0 7 7 7 6 Condensation domain PP-binding PF00550.25 KFH43976.1 - 3.8e-55 184.1 7.8 1.6e-10 41.2 0.1 7.3 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH43976.1 - 2.9e-14 53.8 0.0 0.0014 19.6 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KFH43976.1 - 5.4e-07 28.6 0.1 0.28 9.8 0.0 5.0 6 0 0 6 6 6 2 Transferase family WES_acyltransf PF03007.16 KFH43976.1 - 5.2e-05 23.1 0.6 1.3 8.8 0.1 4.3 4 0 0 4 4 4 2 Wax ester synthase-like Acyl-CoA acyltransferase domain HET PF06985.11 KFH43977.1 - 4.2e-11 43.4 6.9 6e-10 39.7 0.3 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 KFH43978.1 - 3.4e-52 177.7 0.0 4.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH43978.1 - 7.1e-37 127.1 0.0 1.1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFH43978.1 - 2.1e-05 23.7 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFH43978.1 - 8.1e-05 22.8 0.1 0.00021 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH43978.1 - 0.0005 19.3 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFH43978.1 - 0.0026 17.0 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH43978.1 - 0.0067 16.1 0.2 0.03 13.9 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFH43978.1 - 0.019 13.8 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KFH43978.1 - 0.038 12.7 0.0 0.1 11.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KFH43978.1 - 0.09 13.3 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KFH43979.1 - 7.7e-11 41.9 0.0 9.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH43979.1 - 0.0015 17.9 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclase PF04199.13 KFH43981.1 - 9.9e-19 67.9 0.4 3.6e-18 66.1 0.2 1.8 1 1 1 2 2 2 1 Putative cyclase Proteasome PF00227.26 KFH43982.1 - 4e-61 205.8 0.1 4.9e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFH43982.1 - 3.5e-13 48.9 0.1 8.7e-13 47.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KFH43982.1 - 0.012 15.7 0.7 0.04 14.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KFH43982.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Med7 PF05983.11 KFH43983.1 - 1.1e-59 201.7 0.0 1.3e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 MED7 protein FAD_binding_2 PF00890.24 KFH43984.1 - 7e-70 236.2 0.0 9.9e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFH43984.1 - 2.2e-07 30.6 0.2 3.4e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH43984.1 - 4.1e-05 22.5 0.1 6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KFH43984.1 - 0.00024 21.2 0.9 0.00069 19.8 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH43984.1 - 0.00052 19.3 0.0 0.00095 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH43984.1 - 0.0012 18.5 2.6 0.0067 16.1 2.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH43984.1 - 0.0052 16.0 0.1 0.0099 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFH43984.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F-box PF00646.33 KFH43985.1 - 1.1e-07 31.5 0.2 1.1e-07 31.5 0.2 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFH43985.1 - 1.9e-07 30.9 1.8 3.1e-07 30.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KFH43985.1 - 0.00021 21.2 0.1 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 F-box RPEL PF02755.15 KFH43985.1 - 0.00024 20.7 0.3 0.0021 17.7 0.2 2.4 2 0 0 2 2 2 1 RPEL repeat DUF305 PF03713.13 KFH43986.1 - 0.031 14.4 0.8 0.046 13.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF305) GlgS PF08971.11 KFH43986.1 - 0.61 10.2 0.1 0.61 10.2 0.1 2.1 2 0 0 2 2 2 0 Glycogen synthesis protein Aldedh PF00171.22 KFH43988.1 - 2.8e-148 494.3 0.0 3.3e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KFH43989.1 - 2.8e-16 59.4 49.5 2.8e-16 59.4 49.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH43989.1 - 1.4e-05 23.7 23.4 2.6e-05 22.9 23.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TNFR_16_TM PF18422.1 KFH43989.1 - 0.27 11.2 2.3 1.1 9.3 2.3 2.0 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain NTP_transferase PF00483.23 KFH43990.1 - 1.9e-31 109.6 0.0 2.7e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFH43990.1 - 3e-11 42.6 3.7 2.7e-05 23.7 0.0 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFH43990.1 - 2.5e-07 31.2 0.0 4.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KFH43990.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FF PF01846.19 KFH43991.1 - 3.8e-12 46.2 7.0 6.8e-10 39.0 0.3 2.8 2 0 0 2 2 2 2 FF domain WW PF00397.26 KFH43991.1 - 2.1e-09 37.3 4.2 6.2e-09 35.8 4.2 1.9 1 0 0 1 1 1 1 WW domain DUF5641 PF18701.1 KFH43991.1 - 0.018 15.2 0.5 0.042 14.0 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Nuc_sug_transp PF04142.15 KFH43992.1 - 9.4e-101 337.1 2.0 1.2e-100 336.7 2.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFH43992.1 - 2e-08 34.5 23.8 1.4e-05 25.2 3.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFH43992.1 - 6.3e-07 28.9 5.8 4.2e-06 26.2 1.2 2.2 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.16 KFH43992.1 - 0.021 14.2 8.3 0.27 10.5 1.6 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family TMEM234 PF10639.9 KFH43992.1 - 3 7.9 11.0 2.4 8.2 1.7 2.7 3 0 0 3 3 3 0 Putative transmembrane family 234 DMT_6 PF04342.12 KFH43992.1 - 3.7 7.8 8.4 16 5.8 1.2 2.6 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) DUF1479 PF07350.12 KFH43993.1 - 1.5e-145 485.2 0.0 2.4e-145 484.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) bZIP_1 PF00170.21 KFH43994.1 - 1.3e-05 25.2 12.5 0.00052 20.1 0.3 3.4 3 1 0 3 3 3 2 bZIP transcription factor DUF948 PF06103.11 KFH43994.1 - 0.0014 18.9 3.2 0.48 10.7 1.9 2.7 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 KFH43994.1 - 0.0031 17.8 19.6 0.057 13.7 11.1 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFH43994.1 - 0.0082 16.2 4.8 0.019 15.0 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF4559 PF15112.6 KFH43994.1 - 0.011 15.5 10.5 0.16 11.6 2.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4559) UPF0242 PF06785.11 KFH43994.1 - 0.019 15.1 14.7 0.069 13.3 15.3 1.6 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KFH43994.1 - 0.02 14.3 5.7 0.022 14.1 2.6 2.0 1 1 1 2 2 2 0 FAM76 protein Fib_alpha PF08702.10 KFH43994.1 - 0.022 14.9 4.6 0.035 14.3 0.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 KFH43994.1 - 0.042 13.9 0.2 0.042 13.9 0.2 4.2 3 1 2 5 5 5 0 Basic region leucine zipper Atg14 PF10186.9 KFH43994.1 - 0.063 12.4 10.7 0.54 9.3 10.7 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 KFH43994.1 - 0.064 12.9 7.9 3.3 7.3 8.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF812 PF05667.11 KFH43994.1 - 0.085 11.7 8.7 0.11 11.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HOOK PF05622.12 KFH43994.1 - 0.11 10.6 16.1 0.19 9.8 15.8 1.5 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 KFH43994.1 - 0.11 12.5 23.4 0.051 13.6 6.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 KFH43994.1 - 0.14 11.9 9.8 0.45 10.2 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4618 PF15397.6 KFH43994.1 - 0.19 11.1 13.9 0.072 12.5 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) AAA_13 PF13166.6 KFH43994.1 - 0.23 10.1 8.2 0.31 9.6 8.2 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KFH43994.1 - 0.38 10.8 8.6 9 6.3 5.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 KFH43994.1 - 0.42 10.9 4.8 1.2 9.4 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper SHE3 PF17078.5 KFH43994.1 - 0.46 10.2 11.3 0.017 14.8 3.8 1.9 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 KFH43994.1 - 0.46 9.9 18.3 0.65 9.4 18.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 ZapB PF06005.12 KFH43994.1 - 0.73 10.3 25.8 0.67 10.4 0.9 3.3 1 1 2 3 3 3 0 Cell division protein ZapB Fez1 PF06818.15 KFH43994.1 - 0.94 9.9 15.3 1.3 9.5 2.8 2.0 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KFH43994.1 - 0.97 8.7 12.1 2 7.7 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 KFH43994.1 - 1.2 8.9 18.7 3.8 7.2 18.7 1.8 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B YabA PF06156.13 KFH43994.1 - 1.2 9.8 16.6 0.17 12.5 0.6 3.2 1 1 2 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KFH43994.1 - 1.2 9.1 20.6 0.11 12.5 2.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 KFH43994.1 - 1.5 8.2 12.7 2.2 7.7 12.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1542 PF07564.11 KFH43994.1 - 1.6 8.9 4.4 0.57 10.3 1.6 1.7 2 0 0 2 2 1 0 Domain of Unknown Function (DUF1542) DUF1640 PF07798.11 KFH43994.1 - 1.9 8.5 12.2 1 9.4 7.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 KFH43994.1 - 2.1 8.6 12.3 1.1 9.5 1.0 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 KFH43994.1 - 2.1 8.0 12.6 27 4.3 12.6 2.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec34 PF04136.15 KFH43994.1 - 2.2 8.1 6.2 1.3 8.9 0.1 2.6 1 1 2 3 3 3 0 Sec34-like family Exonuc_VII_L PF02601.15 KFH43994.1 - 2.3 7.7 9.8 3.3 7.2 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 KFH43994.1 - 2.3 8.3 18.2 0.7 10.0 0.8 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KFH43994.1 - 2.5 6.0 4.0 3.5 5.5 4.0 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KFH43994.1 - 2.6 6.8 17.4 6.5 5.5 15.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KFH43994.1 - 4 7.2 18.4 14 5.4 18.6 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SpecificRecomb PF10136.9 KFH43994.1 - 4.5 5.5 6.6 8 4.6 6.6 1.4 1 1 0 1 1 1 0 Site-specific recombinase Snapin_Pallidin PF14712.6 KFH43994.1 - 4.9 7.6 11.2 43 4.6 0.1 3.0 1 1 2 3 3 3 0 Snapin/Pallidin LUC7 PF03194.15 KFH43994.1 - 5.1 6.7 12.2 20 4.7 12.2 1.8 1 1 0 1 1 1 0 LUC7 N_terminus Rootletin PF15035.6 KFH43994.1 - 5.1 7.1 20.1 1.9 8.4 11.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 KFH43994.1 - 5.2 4.9 7.0 7.2 4.4 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 KFH43994.1 - 6.2 7.3 13.1 10 6.6 9.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2205 PF10224.9 KFH43994.1 - 9.1 6.4 10.5 1.4 8.9 0.4 3.0 1 1 2 3 3 3 0 Short coiled-coil protein Dynamin_N PF00350.23 KFH43995.1 - 1e-21 77.7 0.0 4.7e-21 75.6 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH43995.1 - 3.7e-11 42.8 1.4 4.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KFH43995.1 - 9.3e-07 28.9 1.1 4.7e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain Amidase02_C PF12123.8 KFH43995.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase MMR_HSR1 PF01926.23 KFH43995.1 - 0.12 12.5 0.0 0.87 9.7 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gag_MA PF01140.19 KFH43995.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Matrix protein (MA), p15 ABC_tran PF00005.27 KFH43995.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PAP2 PF01569.21 KFH43996.1 - 1.4e-25 89.7 0.3 1.4e-25 89.7 0.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily HisKA_7TM PF16927.5 KFH43996.1 - 0.042 13.9 5.2 0.025 14.6 2.6 1.8 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase DUF3093 PF11292.8 KFH43996.1 - 0.069 13.4 0.3 0.31 11.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Hira PF07569.11 KFH43997.1 - 2.1e-83 279.5 0.0 5.9e-83 278.0 0.0 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KFH43997.1 - 1.4e-29 101.7 23.6 2.1e-05 25.2 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH43997.1 - 4.1e-17 62.3 0.0 0.0087 16.3 0.0 6.6 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KFH43997.1 - 8.1e-10 38.3 0.5 2.4e-09 36.8 0.5 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KFH43997.1 - 9.7e-07 28.6 0.4 7 6.7 0.1 5.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFH43997.1 - 0.0011 18.0 0.3 0.23 10.4 0.0 3.8 3 1 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KFH43997.1 - 0.56 10.8 3.4 38 4.9 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain NUDIX PF00293.28 KFH43998.1 - 9.6e-13 48.3 0.1 2e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 KFH44000.1 - 1.7e-12 48.3 2.0 3.7e-12 47.2 2.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH44000.1 - 0.00025 21.3 1.7 0.0054 16.9 1.7 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_5 PF06172.11 KFH44001.1 - 4.9e-44 149.9 0.0 6.2e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) polyprenyl_synt PF00348.17 KFH44002.1 - 8.4e-50 169.2 0.0 1.7e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase TRI5 PF06330.11 KFH44002.1 - 0.068 12.0 0.1 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) Transferase PF02458.15 KFH44003.1 - 1.2e-05 24.2 0.0 3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Transferase family p450 PF00067.22 KFH44004.1 - 1.6e-16 60.1 0.4 1.6e-16 60.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 KFH44005.1 - 9.6e-13 48.1 0.3 9.6e-13 48.1 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain ALMT PF11744.8 KFH44005.1 - 2.7 6.7 6.3 3.6 6.3 6.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Fungal_trans PF04082.18 KFH44006.1 - 1.8e-66 223.9 0.1 2.7e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFH44006.1 - 4.2e-07 30.1 12.9 0.00078 19.8 0.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH44006.1 - 0.088 13.7 14.9 0.19 12.6 0.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH44006.1 - 3 8.4 12.9 5.8 7.5 3.6 3.7 3 0 0 3 3 3 0 Zinc-finger double domain p450 PF00067.22 KFH44007.1 - 4.1e-06 25.8 0.0 6.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.6 KFH44008.1 - 2.2e-27 95.3 8.6 6.9e-14 52.0 0.1 4.2 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KFH44008.1 - 2.4e-20 71.1 6.5 0.0022 18.5 0.1 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KFH44008.1 - 7.2e-08 32.0 6.2 0.048 13.9 0.0 6.6 7 1 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KFH44008.1 - 2.6e-05 24.6 7.5 0.082 13.4 0.0 5.3 5 1 2 7 7 7 1 HEAT-like repeat Arm PF00514.23 KFH44008.1 - 0.0035 17.3 0.1 5.6 7.2 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFH44008.1 - 0.022 14.8 0.0 1.1 9.2 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ERAP1_C PF11838.8 KFH44008.1 - 0.034 13.7 0.4 3.8 7.0 0.0 2.4 2 1 0 2 2 2 0 ERAP1-like C-terminal domain ParA PF10609.9 KFH44009.1 - 5.4e-94 314.3 0.0 6.3e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFH44009.1 - 2.3e-08 34.1 0.0 4e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFH44009.1 - 7.7e-05 22.7 0.1 0.00086 19.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFH44009.1 - 0.00065 19.0 0.4 0.0027 16.9 0.1 1.9 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KFH44009.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFH44009.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase Fer4_NifH PF00142.18 KFH44009.1 - 0.02 14.4 0.0 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KFH44009.1 - 0.02 14.7 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MipZ PF09140.11 KFH44009.1 - 0.03 13.6 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 KFH44009.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KFH44009.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KFH44009.1 - 0.081 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KFH44009.1 - 0.084 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFH44009.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 KFH44009.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFH44009.1 - 0.22 11.1 0.0 0.85 9.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ras PF00071.22 KFH44009.1 - 0.26 10.8 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 Ras family 4HBT PF03061.22 KFH44010.1 - 1.6e-11 44.4 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFH44010.1 - 0.0031 17.8 0.1 0.0046 17.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily FA_desaturase PF00487.24 KFH44011.1 - 2.1e-17 63.8 12.1 2.1e-17 63.8 12.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFH44011.1 - 6e-17 61.6 0.1 2.3e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TFIIB PF00382.19 KFH44012.1 - 0.0018 18.3 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF3439 PF11921.8 KFH44013.1 - 0.048 13.6 2.8 0.076 13.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Totivirus_coat PF05518.11 KFH44013.1 - 9.8 4.1 7.9 13 3.7 7.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein RPN1_RPN2_N PF17781.1 KFH44014.1 - 4e-109 364.8 7.3 5.4e-109 364.3 6.7 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFH44014.1 - 9.9e-30 102.4 0.0 1.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFH44014.1 - 2e-17 62.6 19.9 7e-06 26.2 0.3 8.3 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFH44014.1 - 3e-05 24.3 0.1 0.61 10.5 0.0 4.4 4 2 0 4 4 4 2 HEAT repeats Mn_catalase PF05067.12 KFH44014.1 - 0.049 12.6 0.1 0.095 11.7 0.1 1.4 1 0 0 1 1 1 0 Manganese containing catalase Ras PF00071.22 KFH44016.1 - 5.9e-60 201.5 0.1 6.9e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH44016.1 - 4.2e-21 75.4 0.0 6.1e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH44016.1 - 2.1e-09 37.1 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH44016.1 - 2.6e-06 27.1 0.1 1.8e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH44016.1 - 0.00028 20.8 0.2 0.72 9.7 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFH44016.1 - 0.00056 20.0 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFH44016.1 - 0.0049 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFH44016.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KFH44016.1 - 0.025 13.9 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFH44016.1 - 0.11 12.3 0.8 4.1 7.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RRM_1 PF00076.22 KFH44017.1 - 4.3e-23 80.9 0.0 2.2e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2034 PF10356.9 KFH44018.1 - 3.6e-30 104.8 0.0 1.5e-16 60.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KFH44018.1 - 1.5e-08 34.6 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease FAD_binding_1 PF00667.20 KFH44019.1 - 3.4e-64 216.5 0.0 5.3e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFH44019.1 - 1.9e-33 115.6 1.2 4.2e-33 114.6 1.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFH44019.1 - 4.8e-20 72.2 0.0 4e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFH44019.1 - 0.073 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain NTPase_I-T PF01931.18 KFH44020.1 - 4.5e-56 189.1 0.0 5e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 F-box PF00646.33 KFH44022.1 - 7.8e-07 28.8 0.5 2.5e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFH44022.1 - 1.1e-05 25.2 1.4 1.3e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KFH44022.1 - 0.0048 16.8 1.2 0.0059 16.5 0.1 1.7 2 0 0 2 2 2 1 F-box p450 PF00067.22 KFH44023.1 - 7.6e-68 229.3 0.0 1e-67 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tex_N PF09371.10 KFH44023.1 - 0.22 11.2 0.0 1.9 8.1 0.0 2.1 1 1 0 1 1 1 0 Tex-like protein N-terminal domain MOR2-PAG1_N PF14222.6 KFH44024.1 - 5.8e-219 728.6 0.0 9.2e-219 728.0 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFH44024.1 - 1.9e-92 309.7 0.5 7.9e-92 307.7 0.0 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFH44024.1 - 6.3e-34 116.9 6.2 7e-13 47.2 0.1 3.3 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.6 KFH44024.1 - 0.005 17.2 0.6 1.4 9.3 0.0 4.9 5 1 1 6 6 6 1 HEAT repeats RPAP3_C PF13877.6 KFH44024.1 - 0.035 14.6 0.1 3.6 8.2 0.0 2.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 HEAT_EZ PF13513.6 KFH44024.1 - 0.08 13.5 1.9 0.53 10.9 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KFH44024.1 - 0.28 11.6 2.8 2.8 8.4 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat IML1 PF12257.8 KFH44025.1 - 1.2e-117 392.1 0.0 1.9e-117 391.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KFH44025.1 - 6.7e-26 90.2 0.1 1.4e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) p450 PF00067.22 KFH44026.1 - 1.3e-31 109.9 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FNIP_N PF14636.6 KFH44027.1 - 1.5e-39 136.5 0.5 1.5e-39 136.5 0.5 4.5 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus Nipped-B_C PF12830.7 KFH44028.1 - 3.2e-52 177.2 10.7 4.2e-49 167.1 0.1 4.1 5 0 0 5 5 5 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFH44028.1 - 1.2e-06 28.7 4.3 2.5e-06 27.7 1.1 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFH44028.1 - 9.8e-05 22.3 6.4 3.2 8.3 0.2 5.4 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KFH44028.1 - 0.00042 20.4 1.0 0.19 11.7 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFH44028.1 - 0.0005 18.8 0.1 0.0098 14.5 0.1 2.7 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_2 PF13646.6 KFH44028.1 - 0.00086 19.7 2.7 0.086 13.2 1.0 3.6 2 1 1 3 3 3 2 HEAT repeats AT_hook PF02178.19 KFH44028.1 - 0.035 13.9 2.3 0.17 11.9 2.3 2.3 1 0 0 1 1 1 0 AT hook motif WbqC PF08889.11 KFH44028.1 - 0.13 12.2 0.3 0.49 10.3 0.1 2.1 2 0 0 2 2 2 0 WbqC-like protein family HEAT_EZ PF13513.6 KFH44028.1 - 0.31 11.6 2.7 30 5.2 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat TFIIS_C PF01096.18 KFH44029.1 - 4.6e-12 45.6 1.2 4.6e-12 45.6 1.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFH44029.1 - 8.5e-07 28.7 0.7 8.5e-07 28.7 0.7 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit UCH_1 PF13423.6 KFH44029.1 - 0.0014 18.3 4.0 0.0014 18.3 4.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TackOD1 PF18551.1 KFH44029.1 - 0.0045 16.7 2.9 0.038 13.6 0.1 2.1 2 0 0 2 2 2 1 Thaumarchaeal output domain 1 zinc_ribbon_2 PF13240.6 KFH44029.1 - 0.0068 16.1 4.2 1.6 8.5 0.2 3.4 3 0 0 3 3 3 1 zinc-ribbon domain ArfGap PF01412.18 KFH44029.1 - 0.018 15.1 4.6 0.43 10.7 0.2 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf NOB1_Zn_bind PF08772.11 KFH44029.1 - 0.022 14.9 5.9 9 6.5 3.7 3.2 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 KFH44029.1 - 0.03 14.3 7.6 0.1 12.7 0.6 2.3 2 1 0 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 KFH44029.1 - 0.07 12.7 4.3 9.4 5.9 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFH44029.1 - 0.096 12.8 4.6 5.8 7.1 1.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L37ae PF01780.19 KFH44029.1 - 0.11 12.6 0.8 0.11 12.6 0.8 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 KFH44029.1 - 0.11 12.4 9.9 0.31 11.0 3.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF1922 PF09082.10 KFH44029.1 - 0.17 12.2 6.3 20 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1922) zf-RING_7 PF02591.15 KFH44029.1 - 0.23 11.6 4.4 37 4.6 0.0 3.6 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-UBR PF02207.20 KFH44029.1 - 0.33 11.1 11.0 1.9 8.7 3.7 2.9 2 2 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) GFA PF04828.14 KFH44029.1 - 0.82 10.1 7.0 19 5.7 3.6 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme PLATZ PF04640.14 KFH44029.1 - 1.4 9.6 6.3 3.7 8.2 0.6 2.4 2 1 0 2 2 2 0 PLATZ transcription factor Nudix_N_2 PF14803.6 KFH44029.1 - 1.4 8.9 5.1 36 4.4 0.0 2.9 2 1 0 2 2 2 0 Nudix N-terminal zf-CHY PF05495.12 KFH44029.1 - 1.6 9.3 7.1 1.4 9.4 0.7 2.5 2 1 0 2 2 2 0 CHY zinc finger zf-HYPF PF07503.12 KFH44029.1 - 2.3 8.1 5.5 15 5.5 0.1 3.2 3 0 0 3 3 3 0 HypF finger Baculo_LEF5_C PF11792.8 KFH44029.1 - 3 7.6 6.6 2.3 8.0 0.1 2.8 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain HalOD2 PF18547.1 KFH44029.1 - 3.1 7.8 0.0 3.1 7.8 0.0 3.3 3 1 0 3 3 3 0 Halobacterial output domain 2 A2L_zn_ribbon PF08792.10 KFH44029.1 - 5.3 6.9 11.2 29 4.5 0.2 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.5 KFH44029.1 - 5.9 7.7 11.1 3 8.7 4.7 2.6 1 1 1 2 2 2 0 zinc-ribbon family p450 PF00067.22 KFH44030.1 - 1.5e-11 43.7 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DnaJ_C PF01556.18 KFH44031.1 - 5.7e-38 130.3 0.0 8.1e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFH44031.1 - 5.1e-25 87.4 0.7 8.7e-25 86.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFH44031.1 - 1e-09 38.6 21.1 2.1e-09 37.6 21.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFH44031.1 - 0.59 10.1 20.6 0.045 13.7 2.8 3.2 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein WSC PF01822.19 KFH44032.1 - 6.2e-10 39.1 9.5 6.2e-10 39.1 9.5 2.5 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.21 KFH44032.1 - 9.1e-06 25.3 0.2 2.5e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Trypan_PARP PF05887.11 KFH44032.1 - 0.0034 17.4 9.8 0.0034 17.4 9.8 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KFH44032.1 - 0.15 11.2 1.7 0.23 10.6 1.7 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 RIO1 PF01163.22 KFH44033.1 - 9e-42 142.8 0.1 3.6e-41 140.9 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KFH44033.1 - 8.7e-33 112.4 0.0 1.9e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KFH44033.1 - 8.1e-07 29.2 0.1 0.0022 17.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFH44033.1 - 2.9e-06 26.8 0.0 0.0044 16.4 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family BUD22 PF09073.10 KFH44033.1 - 0.18 11.1 16.6 1.4 8.2 18.0 1.6 2 0 0 2 2 2 0 BUD22 CobT PF06213.12 KFH44033.1 - 0.82 9.0 24.8 1.2 8.4 24.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 KFH44033.1 - 0.84 8.9 18.8 1.4 8.1 18.8 1.3 1 0 0 1 1 1 0 NOA36 protein PTPRCAP PF15713.5 KFH44033.1 - 2.2 8.5 22.0 3.9 7.8 22.0 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 KFH44033.1 - 2.3 6.3 23.0 3 5.9 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 KFH44033.1 - 2.4 6.9 5.3 3.4 6.3 5.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 KFH44033.1 - 2.6 6.2 16.0 3.6 5.8 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SAP30_Sin3_bdg PF13867.6 KFH44034.1 - 6.4e-11 42.4 0.8 4.4e-09 36.5 0.1 2.6 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4286 PF14114.6 KFH44034.1 - 0.02 15.4 0.0 0.051 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) dsRBD2 PF17842.1 KFH44034.1 - 0.052 13.8 0.8 0.077 13.2 0.3 1.6 1 1 1 2 2 2 0 Double-stranded RNA binding domain 2 Xpo1 PF08389.12 KFH44036.1 - 3.5e-27 95.3 0.9 3.2e-26 92.2 0.2 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KFH44036.1 - 3.2e-07 30.1 0.2 8.1e-07 28.9 0.2 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 KFH44036.1 - 0.016 15.1 3.3 9.3 6.2 0.0 4.8 4 2 0 4 4 4 0 UME (NUC010) domain Adaptin_N PF01602.20 KFH44036.1 - 0.023 13.3 0.3 0.51 8.8 0.2 2.4 2 0 0 2 2 2 0 Adaptin N terminal region PI3Ka PF00613.20 KFH44036.1 - 0.052 12.9 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Tab2_like PF06485.11 KFH44036.1 - 0.056 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Pkinase PF00069.25 KFH44037.1 - 4.4e-11 42.6 0.0 4.8e-10 39.3 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44037.1 - 7.2e-09 35.3 0.0 6.8e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KFH44038.1 - 4.4e-10 40.0 1.1 0.0003 21.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44038.1 - 0.041 14.2 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Serglycin PF04360.12 KFH44038.1 - 5.2 7.0 6.9 11 5.9 6.9 1.5 1 0 0 1 1 1 0 Serglycin Pex2_Pex12 PF04757.14 KFH44039.1 - 6.4e-53 179.6 3.6 8.5e-53 179.2 3.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KFH44039.1 - 0.011 15.9 2.6 0.019 15.1 2.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFH44039.1 - 0.024 15.0 3.4 0.041 14.2 3.4 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KFH44039.1 - 0.049 13.5 2.0 0.076 12.9 2.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH44039.1 - 0.049 13.5 3.2 0.086 12.7 3.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH44039.1 - 0.24 11.3 2.1 0.44 10.5 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KFH44039.1 - 1.2 9.5 4.0 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon GST_C PF00043.25 KFH44040.1 - 4.2e-13 49.3 0.1 1.6e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFH44040.1 - 2.4e-12 47.0 0.0 1.2e-09 38.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFH44040.1 - 3.2e-12 46.7 0.0 7.9e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFH44040.1 - 5e-12 45.9 0.0 9.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFH44040.1 - 6.7e-11 42.1 0.1 2.2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFH44040.1 - 1.2e-10 41.5 0.0 2.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFH44040.1 - 0.015 16.0 0.0 0.15 12.8 0.0 2.3 2 1 1 3 3 3 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFH44040.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OPT PF03169.15 KFH44041.1 - 2e-202 674.2 35.7 2.3e-202 673.9 35.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.20 KFH44042.1 - 2.7e-29 102.4 0.0 3.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Lon_C PF05362.13 KFH44043.1 - 8.1e-64 214.9 0.0 1.6e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFH44043.1 - 3.8e-31 108.6 0.2 1.1e-30 107.1 0.2 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFH44043.1 - 3e-21 76.2 0.0 7.8e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KFH44043.1 - 3.7e-08 33.3 0.0 9.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KFH44043.1 - 1.5e-06 28.3 0.0 4.8e-06 26.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH44043.1 - 3.7e-06 27.2 0.0 1.4e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KFH44043.1 - 6.3e-05 22.1 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KFH44043.1 - 8.2e-05 22.9 0.0 0.0014 18.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFH44043.1 - 9.5e-05 22.2 0.1 0.00064 19.5 0.0 2.4 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH44043.1 - 0.00032 21.1 0.8 0.0018 18.7 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFH44043.1 - 0.012 16.1 0.3 0.079 13.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain DNTTIP1_dimer PF18192.1 KFH44043.1 - 0.014 15.7 0.4 0.44 10.9 0.1 3.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain IstB_IS21 PF01695.17 KFH44043.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFH44043.1 - 0.023 14.4 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFH44043.1 - 0.03 14.3 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFH44043.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4276 PF14103.6 KFH44043.1 - 0.038 14.2 3.2 0.93 9.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) RsgA_GTPase PF03193.16 KFH44043.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ClpB_D2-small PF10431.9 KFH44043.1 - 0.12 12.5 6.4 0.077 13.1 0.4 3.1 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein AAA_7 PF12775.7 KFH44043.1 - 0.16 11.5 0.8 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KFH44043.1 - 0.71 10.4 5.6 0.88 10.1 0.0 3.0 3 0 0 3 3 3 0 ABC transporter MoCF_biosynth PF00994.24 KFH44044.1 - 6.8e-34 116.6 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DIM1 PF02966.16 KFH44045.1 - 4.4e-69 230.4 0.1 4.9e-69 230.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFH44045.1 - 0.00035 20.5 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFH44045.1 - 0.019 15.3 0.4 0.035 14.4 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin-like DEAD PF00270.29 KFH44046.1 - 8.3e-48 162.5 0.1 1.6e-46 158.3 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH44046.1 - 1.1e-25 90.1 0.1 4.5e-24 84.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFH44046.1 - 2.3e-20 72.6 1.8 7.9e-20 70.9 1.8 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KFH44046.1 - 1.1e-07 32.1 0.0 3.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AMP-binding PF00501.28 KFH44047.1 - 1.7e-72 244.3 0.0 2.9e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFH44047.1 - 2.3e-51 174.9 0.0 3.5e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KFH44047.1 - 6.8e-49 166.2 0.1 1e-47 162.4 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KFH44047.1 - 1.3e-44 152.6 0.0 2.3e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH44047.1 - 5.8e-39 134.5 0.0 1e-38 133.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KFH44047.1 - 2.4e-33 115.4 0.0 5.5e-33 114.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFH44047.1 - 1.7e-20 73.5 0.0 2.1e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFH44047.1 - 1.6e-19 70.0 0.4 3.3e-10 40.2 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KFH44047.1 - 1.7e-14 54.3 0.0 8.1e-14 52.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH44047.1 - 4.2e-14 52.7 0.0 9.8e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH44047.1 - 1.6e-12 47.3 1.6 8.9e-11 41.6 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFH44047.1 - 5.8e-12 46.2 0.0 1.9e-10 41.3 0.0 3.7 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH44047.1 - 1.2e-10 41.9 0.0 1.1e-09 38.8 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 KFH44047.1 - 1.4e-08 34.6 0.0 8e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_31 PF13847.6 KFH44047.1 - 2e-08 34.2 0.0 5.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KFH44047.1 - 9.6e-07 28.1 0.0 3.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KFH44047.1 - 7.9e-05 22.3 0.5 0.0022 17.6 0.0 2.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase UPF0176_N PF17773.1 KFH44047.1 - 0.02 15.3 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Methyltransf_24 PF13578.6 KFH44047.1 - 0.029 15.4 0.5 0.25 12.4 0.0 2.9 3 0 0 3 3 1 0 Methyltransferase domain AMP-binding_C PF13193.6 KFH44047.1 - 0.037 15.0 0.0 0.19 12.7 0.0 2.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PCMT PF01135.19 KFH44047.1 - 0.1 12.3 0.0 0.52 10.0 0.0 2.2 3 0 0 3 3 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KFH44048.1 - 2.3e-24 86.0 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFH44049.1 - 3.1e-39 134.9 25.9 3.1e-39 134.9 25.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily YbhQ PF11076.8 KFH44049.1 - 0.1 12.6 2.7 9 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Torus PF16131.5 KFH44051.1 - 1e-07 32.6 0.2 0.0098 16.6 0.1 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KFH44051.1 - 4.8e-07 29.5 9.2 1.1e-05 25.2 0.7 3.3 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFH44051.1 - 2.7e-06 27.2 15.2 9.7e-06 25.5 5.6 3.3 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFH44051.1 - 8.4e-06 25.5 4.0 8.4e-06 25.5 4.0 4.0 4 1 0 4 4 4 2 CCCH-type zinc finger DUF4710 PF15828.5 KFH44051.1 - 0.27 11.4 1.3 0.54 10.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF4192 PF13830.6 KFH44052.1 - 0.063 13.3 0.5 0.1 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) PRKCSH-like PF12999.7 KFH44053.1 - 2.6e-39 134.8 14.0 2.3e-23 82.9 0.4 3.8 5 0 0 5 5 5 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KFH44053.1 - 5e-32 110.7 2.3 5.6e-32 110.6 0.6 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFH44053.1 - 9.8e-12 45.7 1.2 4e-11 43.8 1.2 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KFH44053.1 - 0.0071 16.2 0.4 0.016 15.1 0.3 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 Mod_r PF07200.13 KFH44053.1 - 0.01 15.9 5.9 0.37 10.9 0.1 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.6 KFH44053.1 - 0.023 14.7 2.7 0.23 11.5 0.3 2.9 3 0 0 3 3 3 0 FlxA-like protein DFF-C PF09033.10 KFH44053.1 - 0.029 14.3 1.2 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DUF728 PF05304.12 KFH44053.1 - 0.047 13.5 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Mig-14 PF07395.11 KFH44053.1 - 0.11 11.8 1.9 0.2 11.0 1.9 1.4 1 0 0 1 1 1 0 Mig-14 DUF4407 PF14362.6 KFH44053.1 - 0.22 10.9 7.9 0.38 10.0 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CASP_C PF08172.12 KFH44053.1 - 0.34 10.2 7.5 0.22 10.8 4.5 1.9 2 0 0 2 2 2 0 CASP C terminal Snapin_Pallidin PF14712.6 KFH44053.1 - 0.62 10.5 4.8 0.87 10.1 0.0 2.6 3 0 0 3 3 2 0 Snapin/Pallidin DivIC PF04977.15 KFH44053.1 - 0.78 9.6 12.0 6.8 6.5 0.0 3.6 3 1 0 3 3 3 0 Septum formation initiator CCCAP PF15964.5 KFH44053.1 - 2 6.6 13.8 1.2 7.4 11.1 1.8 1 1 1 2 2 2 0 Centrosomal colon cancer autoantigen protein family AAA_15 PF13175.6 KFH44053.1 - 2.4 7.8 5.6 37 3.9 5.6 2.4 1 1 0 1 1 1 0 AAA ATPase domain Rab5-bind PF09311.11 KFH44053.1 - 4.2 6.7 13.8 9.2 5.6 11.0 2.5 2 1 0 2 2 2 0 Rabaptin-like protein APG6_N PF17675.1 KFH44053.1 - 6.5 7.3 21.9 15 6.1 0.6 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 KFH44053.1 - 7.4 5.3 15.7 11 4.7 0.2 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein adh_short_C2 PF13561.6 KFH44055.1 - 6.8e-39 133.8 2.8 1.6e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH44055.1 - 5.2e-19 68.5 0.4 8e-13 48.3 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KFH44055.1 - 4.5e-07 29.9 2.8 8.3e-07 29.1 2.8 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFH44055.1 - 4.5e-06 26.9 0.5 1.1e-05 25.7 0.5 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFH44055.1 - 0.00019 21.4 1.3 0.00019 21.4 1.3 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFH44055.1 - 0.00038 21.0 0.8 0.00077 20.0 0.8 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KFH44055.1 - 0.0011 18.5 0.1 0.011 15.1 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH44055.1 - 0.0015 17.6 0.1 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFH44055.1 - 0.0065 16.7 0.4 0.015 15.5 0.3 1.9 1 1 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 KFH44055.1 - 0.013 16.2 0.1 0.029 15.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 KFH44055.1 - 0.039 14.1 0.4 0.083 13.1 0.2 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase B12-binding PF02310.19 KFH44055.1 - 0.04 14.0 0.3 0.092 12.8 0.2 1.7 1 1 0 1 1 1 0 B12 binding domain Shikimate_DH PF01488.20 KFH44055.1 - 0.095 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 KFH44055.1 - 0.16 12.6 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Zn_clus PF00172.18 KFH44056.1 - 5.6e-07 29.6 10.4 9.5e-07 28.8 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH44056.1 - 9.1e-07 28.0 0.0 5.6e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_7 PF00840.20 KFH44057.1 - 3.9e-180 599.2 3.5 4.4e-180 599.1 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Yip1 PF04893.17 KFH44058.1 - 5.1e-05 23.1 18.9 0.00088 19.0 18.9 2.2 1 1 0 1 1 1 1 Yip1 domain MFS_1 PF07690.16 KFH44059.1 - 2.3e-35 122.2 24.2 1.1e-34 119.9 24.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFH44059.1 - 0.27 9.5 4.4 3.9 5.6 0.1 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cupin_2 PF07883.11 KFH44060.1 - 2.8e-14 52.6 0.2 6.4e-14 51.4 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KFH44060.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KFH44060.1 - 3.9e-05 23.3 0.0 5.8e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KFH44060.1 - 0.00015 21.6 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 KFH44060.1 - 0.011 15.3 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Pirin PF02678.16 KFH44060.1 - 0.033 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Pirin SLD5_C PF16922.5 KFH44060.1 - 0.034 14.3 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus EutQ PF06249.12 KFH44060.1 - 0.041 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 KFH44060.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_3 PF01494.19 KFH44061.1 - 7e-17 61.7 0.1 2e-16 60.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH44061.1 - 1.4e-08 34.9 0.7 3.5e-08 33.6 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH44061.1 - 2.7e-05 23.9 4.6 3.8e-05 23.4 3.8 1.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH44061.1 - 6.6e-05 22.3 0.7 0.00016 21.0 0.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH44061.1 - 0.00012 22.5 0.5 0.0004 20.9 0.5 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFH44061.1 - 0.00015 21.2 0.1 0.0052 16.1 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KFH44061.1 - 0.00041 19.6 2.2 0.0018 17.4 1.2 1.9 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFH44061.1 - 0.0012 18.3 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFH44061.1 - 0.0015 17.6 0.1 0.0023 17.0 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KFH44061.1 - 0.045 12.8 1.3 0.072 12.2 1.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KFH44061.1 - 0.077 12.9 0.5 0.14 12.0 0.5 1.5 1 0 0 1 1 1 0 Rossmann-like domain DUF815 PF05673.13 KFH44061.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) 3HCDH_N PF02737.18 KFH44061.1 - 0.2 11.5 1.4 0.36 10.7 1.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KFH44061.1 - 0.47 9.1 1.8 0.81 8.3 1.8 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KFH44061.1 - 0.79 9.4 3.1 1.2 8.8 0.9 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF4551 PF15087.6 KFH44062.1 - 0.053 12.4 2.3 0.058 12.2 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 KFH44062.1 - 0.54 10.2 10.1 0.59 10.1 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 KFH44062.1 - 6 7.0 21.2 1.5 8.9 13.6 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PAP_assoc PF03828.19 KFH44063.1 - 1.2e-10 41.4 0.1 2.4e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFH44063.1 - 9.9e-09 35.4 0.0 2.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.22 KFH44065.1 - 3e-70 237.3 0.0 3.5e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 KFH44066.1 - 4e-25 89.0 0.0 6.1e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFH44066.1 - 2.2e-13 50.3 0.0 3.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFH44066.1 - 5.4e-05 23.8 0.1 9.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH44066.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_DMAT PF11991.8 KFH44067.1 - 5.2e-96 322.2 0.0 8.5e-96 321.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KFH44067.1 - 6.6e-27 94.4 0.0 1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SOG2 PF10428.9 KFH44068.1 - 0.031 13.5 0.1 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ketoacyl-synt PF00109.26 KFH44069.1 - 1.1e-49 169.3 0.0 1.4e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KFH44069.1 - 0.063 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFH44069.1 - 0.11 12.3 0.6 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NmrA PF05368.13 KFH44070.1 - 1.6e-16 60.6 0.0 2.1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH44070.1 - 1.7e-13 50.9 0.0 2.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFH44070.1 - 5.6e-08 33.1 0.0 9.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFH44070.1 - 3.4e-05 23.4 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFH44070.1 - 0.00017 20.9 0.0 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KFH44070.1 - 0.00067 20.1 0.2 0.0044 17.4 0.1 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFH44070.1 - 0.0058 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KFH44070.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 KFH44070.1 - 0.022 15.3 0.1 0.074 13.6 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KFH44070.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KFH44070.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMN_dh PF01070.18 KFH44070.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase adh_short PF00106.25 KFH44070.1 - 0.17 11.4 0.3 0.35 10.3 0.3 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_kinase PF01513.21 KFH44071.1 - 2.6e-45 154.9 0.0 6.5e-45 153.6 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFH44071.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 KFH44072.1 - 1.1e-21 77.2 26.4 1.5e-21 76.8 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_transf_3 PF02515.17 KFH44073.1 - 2.6e-37 128.8 0.0 3.1e-36 125.3 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III KR PF08659.10 KFH44074.1 - 1.3e-52 178.3 0.0 3.6e-52 176.9 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFH44074.1 - 5.2e-39 134.6 0.0 2.3e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KFH44074.1 - 1.1e-36 126.6 0.0 1.9e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFH44074.1 - 2.5e-33 114.6 0.0 5.3e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH44074.1 - 2.5e-16 60.2 0.0 6.5e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH44074.1 - 8.3e-13 48.5 0.0 2.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH44074.1 - 2.2e-12 47.4 0.0 2.9e-11 43.8 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 KFH44074.1 - 2.4e-11 43.7 0.0 4.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_25 PF13649.6 KFH44074.1 - 2.9e-09 37.5 0.0 1.6e-08 35.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH44074.1 - 2.4e-08 33.7 0.0 1.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KFH44074.1 - 2.8e-08 33.7 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH44074.1 - 2.8e-08 34.3 0.0 1.3e-07 32.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH44074.1 - 3.6e-08 33.3 0.0 1.1e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KFH44074.1 - 5.1e-07 30.0 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFH44074.1 - 8.9e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KFH44074.1 - 0.0029 16.9 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain SAT PF16073.5 KFH44074.1 - 0.004 16.9 0.2 0.0097 15.7 0.2 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_zinc_N PF00107.26 KFH44074.1 - 0.016 15.2 0.0 0.072 13.1 0.0 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acyltransferase PF01553.21 KFH44075.1 - 2.3e-30 105.0 0.0 3.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KFH44075.1 - 1.4e-10 41.1 0.1 2.3e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus ESPR PF13018.6 KFH44075.1 - 0.039 13.7 2.1 0.083 12.7 2.1 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system F-box-like PF12937.7 KFH44076.1 - 0.0089 15.9 1.5 0.027 14.4 0.0 2.5 3 0 0 3 3 3 1 F-box-like UFD1 PF03152.14 KFH44077.1 - 1.9e-27 95.9 0.0 1.3e-13 50.7 0.0 3.9 4 0 0 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KFH44077.1 - 1.9e-07 31.2 0.3 8.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A TF_Zn_Ribbon PF08271.12 KFH44077.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2 PF00096.26 KFH44077.1 - 0.29 11.7 12.7 2.6 8.6 0.2 4.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type RCC1 PF00415.18 KFH44078.1 - 2.4e-62 207.4 8.4 7e-11 42.6 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFH44078.1 - 3.9e-40 134.9 28.4 3.6e-11 42.6 0.4 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 KFH44080.1 - 2e-35 122.4 30.7 2.7e-35 121.9 30.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GCIP PF13324.6 KFH44081.1 - 1.9e-19 70.3 0.0 7.7e-19 68.3 0.0 1.9 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting Spt5_N PF11942.8 KFH44081.1 - 0.065 14.2 7.8 0.12 13.4 7.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal IL11 PF07400.11 KFH44081.1 - 0.077 12.6 2.4 0.21 11.2 0.3 2.2 2 0 0 2 2 2 0 Interleukin 11 RCDG1 PF15725.5 KFH44081.1 - 9.6 6.7 9.8 2 8.9 4.6 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Dioxygenase_C PF00775.21 KFH44082.1 - 6.3e-45 152.8 0.0 8.3e-35 119.9 0.0 2.1 2 0 0 2 2 2 2 Dioxygenase Dioxygenase_N PF04444.14 KFH44082.1 - 4.3e-26 90.6 0.0 7.4e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KFH44082.1 - 8.7e-05 22.7 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFH44082.1 - 0.057 13.4 0.0 4 7.5 0.0 2.8 3 0 0 3 3 3 0 CarboxypepD_reg-like domain RHH_8 PF17723.1 KFH44082.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family WAP PF00095.21 KFH44083.1 - 0.3 11.5 12.4 2.9 8.3 1.6 2.6 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Colipase-like PF15083.6 KFH44083.1 - 1.2 9.4 5.4 12 6.1 0.8 2.1 2 0 0 2 2 2 0 Colipase-like Colipase PF01114.18 KFH44083.1 - 2.1 8.1 13.0 3.9 7.2 1.1 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain ACI44 PF15270.6 KFH44083.1 - 7.3 6.9 9.1 9.9 6.4 1.0 2.3 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Squash PF00299.18 KFH44083.1 - 7.6 6.7 11.9 7 6.8 2.3 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor ORC6 PF05460.13 KFH44084.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HGTP_anticodon PF03129.20 KFH44084.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain 5_nucleotid_C PF02872.18 KFH44086.1 - 1.4e-35 122.8 0.0 2.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFH44086.1 - 2.4e-12 47.8 2.6 1.6e-11 45.1 2.3 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KFH44086.1 - 0.044 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein MotA_activ PF09114.10 KFH44086.1 - 0.16 12.1 0.1 0.49 10.6 0.1 1.8 1 0 0 1 1 1 0 Transcription factor MotA, activation domain zf-C3HC4_3 PF13920.6 KFH44087.1 - 0.67 9.9 8.9 1.1 9.2 4.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH44087.1 - 2.7 8.4 9.8 0.52 10.7 5.1 2.1 2 0 0 2 2 2 0 Ring finger domain EthD PF07110.11 KFH44088.1 - 5.4e-14 53.1 0.0 6.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 EthD domain Ribonuc_L-PSP PF01042.21 KFH44089.1 - 1.5e-15 57.3 0.0 1.6e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 Endoribonuclease L-PSP Jag_N PF14804.6 KFH44089.1 - 0.09 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Jag N-terminus polyprenyl_synt PF00348.17 KFH44090.1 - 3.1e-23 82.1 0.0 4.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CotJA PF11007.8 KFH44090.1 - 0.11 12.3 0.2 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) DNA_pol3_a_NII PF11490.8 KFH44090.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PLA2_B PF01735.18 KFH44091.1 - 1e-181 604.7 0.6 1.2e-181 604.4 0.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SnoaL_4 PF13577.6 KFH44092.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.7 KFH44093.1 - 1.2e-20 75.1 0.0 1.5e-20 74.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH44093.1 - 1.2e-13 50.9 0.0 4.4e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH44093.1 - 1.7e-12 47.5 0.2 6e-12 45.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFH44093.1 - 0.0002 21.2 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KFH44093.1 - 0.002 17.9 0.1 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein PAF-AH_p_II PF03403.13 KFH44093.1 - 0.0023 16.5 1.4 0.026 13.1 0.2 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.20 KFH44093.1 - 0.028 14.5 0.0 0.07 13.2 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.13 KFH44093.1 - 0.045 13.6 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase DUF1057 PF06342.12 KFH44093.1 - 0.074 12.1 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase PF00151.19 KFH44093.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipase CFEM PF05730.11 KFH44094.1 - 1.1e-13 51.0 8.5 1.5e-13 50.6 8.5 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.12 KFH44094.1 - 0.0061 16.1 43.2 1e+02 2.5 43.2 2.7 1 1 0 1 1 1 0 PT repeat FAP PF07174.11 KFH44094.1 - 7 6.0 18.0 9.7 5.5 18.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FAD_binding_3 PF01494.19 KFH44095.1 - 3.4e-12 46.3 0.1 4.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain T2SS_PulS_OutS PF09691.10 KFH44095.1 - 0.066 13.4 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) ketoacyl-synt PF00109.26 KFH44096.1 - 4.7e-76 255.7 0.0 7.5e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFH44096.1 - 1.2e-30 105.9 0.0 4.4e-30 104.1 0.0 1.9 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFH44096.1 - 8.2e-06 25.4 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFH44096.1 - 0.019 15.4 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KFH44096.1 - 0.065 13.1 0.6 0.065 13.1 0.6 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CT_C_D PF02682.16 KFH44097.1 - 4.2 7.0 7.6 7.6 6.2 7.6 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D p450 PF00067.22 KFH44098.1 - 2.6e-37 128.6 0.0 3.9e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KFH44098.1 - 1.6e-14 53.9 0.0 4.1e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FBPase_glpX PF03320.13 KFH44098.1 - 0.28 10.0 0.8 0.5 9.2 0.8 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Amidohydro_2 PF04909.14 KFH44099.1 - 1.2e-37 130.2 1.0 1.6e-37 129.9 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF308 PF03729.13 KFH44100.1 - 0.02 15.2 2.7 0.02 15.2 2.7 2.6 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) FtsJ PF01728.19 KFH44101.1 - 7.5e-62 208.6 0.0 9.8e-62 208.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.16 KFH44102.1 - 3.8e-32 111.6 23.1 3.8e-32 111.6 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3827 PF12877.7 KFH44102.1 - 0.052 11.9 0.3 0.14 10.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF21 PF01595.20 KFH44102.1 - 1.3 8.7 5.7 1.3 8.7 0.5 3.1 1 1 2 3 3 3 0 Cyclin M transmembrane N-terminal domain FSH1 PF03959.13 KFH44103.1 - 7.4e-21 74.8 0.0 8.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FBPase PF00316.20 KFH44104.1 - 5e-69 231.6 0.1 6.6e-69 231.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CIA30 PF08547.12 KFH44105.1 - 2.6e-26 92.5 0.0 3.6e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF4874 PF16173.5 KFH44106.1 - 6.4e-13 48.7 0.0 8.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 KFH44106.1 - 0.0001 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) Amidohydro_2 PF04909.14 KFH44107.1 - 2.2e-19 70.4 0.5 4.3e-19 69.4 0.5 1.5 1 1 0 1 1 1 1 Amidohydrolase Caps_synth PF05704.12 KFH44108.1 - 4.7e-13 49.2 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_25 PF13649.6 KFH44108.1 - 2.5e-07 31.3 0.0 6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH44108.1 - 7.4e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Gly_transf_sug PF04488.15 KFH44108.1 - 4.5e-05 24.0 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Methyltransf_12 PF08242.12 KFH44108.1 - 0.1 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFH44108.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3425 PF11905.8 KFH44109.1 - 4.5e-14 52.5 0.0 8.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TFIIA PF03153.13 KFH44109.1 - 2.7 7.9 8.5 3.5 7.5 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_16 PF00722.21 KFH44110.1 - 2e-42 144.6 1.9 3.2e-42 144.0 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.11 KFH44110.1 - 0.34 8.9 12.4 0.52 8.3 12.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CEND1 PF15677.5 KFH44110.1 - 0.96 10.0 15.8 0.35 11.4 11.0 2.4 2 1 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 SOG2 PF10428.9 KFH44110.1 - 2.6 7.1 6.9 3.5 6.7 6.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GST_N_3 PF13417.6 KFH44111.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFH44111.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFH44111.1 - 1.9e-13 50.6 0.0 3.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH44111.1 - 0.00027 20.9 0.1 0.00061 19.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFH44111.1 - 0.0013 19.0 0.0 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C_5 PF16865.5 KFH44111.1 - 0.076 13.6 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SIR2 PF02146.17 KFH44112.1 - 3e-36 125.0 0.0 7.7e-36 123.7 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Peripla_BP_4 PF13407.6 KFH44112.1 - 0.036 13.6 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain TPP_enzyme_M PF00205.22 KFH44112.1 - 0.041 13.6 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Zn-ribbon_8 PF09723.10 KFH44112.1 - 0.054 13.6 1.8 0.079 13.1 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Vps62 PF06101.11 KFH44113.1 - 5.6e-09 34.8 0.5 8.7e-09 34.2 0.5 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Glyco_hydro_43 PF04616.14 KFH44115.1 - 7.6e-36 123.9 5.5 8.6e-36 123.7 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KFH44116.1 - 4.9e-20 71.7 0.0 1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rcd1 PF04078.13 KFH44118.1 - 5.2e-110 366.8 4.9 5.9e-110 366.6 4.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PEX11 PF05648.14 KFH44119.1 - 1.3e-70 237.4 1.0 1.4e-70 237.2 1.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pec_lyase_C PF00544.19 KFH44120.1 - 1e-45 155.9 6.6 1.6e-45 155.3 6.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFH44120.1 - 0.00019 21.3 10.0 0.0012 18.7 9.2 2.2 1 1 1 2 2 2 2 Right handed beta helix region NAD_binding_10 PF13460.6 KFH44121.1 - 4.2e-10 39.8 0.1 5e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFH44121.1 - 4.4e-05 22.6 0.0 5.7e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH44121.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFH44121.1 - 0.00018 20.7 0.0 0.0096 15.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KFH44121.1 - 0.0038 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 KFH44121.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PXA PF02194.15 KFH44122.1 - 9.2e-53 178.9 0.0 4.3e-52 176.7 0.0 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFH44122.1 - 1.7e-27 96.2 0.0 6.4e-27 94.3 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFH44122.1 - 1e-19 70.6 0.5 2.7e-19 69.2 0.5 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KFH44122.1 - 4.1e-13 49.6 0.2 1.2e-12 48.2 0.2 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mod_r PF07200.13 KFH44122.1 - 0.15 12.2 2.6 0.88 9.7 1.1 2.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_holin_3_6 PF07332.11 KFH44122.1 - 0.16 12.0 1.7 0.48 10.5 1.7 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RRP36 PF06102.12 KFH44122.1 - 1.4 8.8 6.3 0.79 9.7 0.3 3.0 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Homoserine_dh PF00742.19 KFH44123.1 - 6.5e-52 175.9 0.0 8.5e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KFH44123.1 - 2.9e-18 66.6 0.0 4.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2791 PF10923.8 KFH44123.1 - 0.018 13.9 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) IGPS PF00218.21 KFH44123.1 - 0.19 10.9 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF1604 PF07713.13 KFH44124.1 - 7.2e-41 137.9 3.0 7.9e-41 137.8 1.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFH44124.1 - 2e-06 27.6 3.2 2.9e-06 27.1 0.4 2.7 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KFH44124.1 - 0.00071 19.6 0.2 0.00071 19.6 0.2 3.2 3 0 0 3 3 3 1 G-patch domain HMG_CoA_synt_C PF08540.10 KFH44125.1 - 1.9e-72 244.3 0.0 2.4e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFH44125.1 - 1.5e-22 80.3 0.0 2.6e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal bZIP_2 PF07716.15 KFH44126.1 - 3.4e-06 27.0 7.0 3.4e-06 27.0 7.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFH44126.1 - 5e-06 26.5 5.6 5e-06 26.5 5.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor TTKRSYEDQ PF10212.9 KFH44126.1 - 0.022 13.8 0.2 0.036 13.1 0.2 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fes1 PF08609.10 KFH44126.1 - 0.2 12.6 1.2 0.58 11.1 0.0 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 bZIP_Maf PF03131.17 KFH44126.1 - 0.63 10.6 14.3 0.64 10.6 2.8 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Methyltransf_11 PF08241.12 KFH44127.1 - 1.6e-12 47.9 0.0 2.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH44127.1 - 5.4e-12 46.2 0.0 1.2e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH44127.1 - 2.5e-09 37.8 0.0 4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH44127.1 - 1.5e-07 31.4 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH44127.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFH44127.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFH44127.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acetyltransf_1 PF00583.25 KFH44128.1 - 1.4e-08 34.9 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH44128.1 - 2.9e-06 27.6 0.0 4.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH44128.1 - 7.5e-06 25.9 0.0 9.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH44128.1 - 0.0038 17.2 0.0 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Far-17a_AIG1 PF04750.14 KFH44128.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Acetyltransf_9 PF13527.7 KFH44128.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Beta-lactamase PF00144.24 KFH44129.1 - 2.4e-41 142.1 0.0 3.2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KFH44130.1 - 1.9e-45 155.3 0.4 2.4e-45 155.0 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44130.1 - 3.1e-09 36.8 7.0 5.9e-09 35.9 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KFH44131.1 - 0.004 17.0 0.4 0.004 17.0 0.4 3.2 3 0 0 3 3 3 2 F-box-like FAD_binding_2 PF00890.24 KFH44132.1 - 1.2e-42 146.5 2.7 2.4e-41 142.2 2.7 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFH44132.1 - 3e-10 40.2 1.1 3e-10 40.2 1.1 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH44132.1 - 2.7e-07 30.3 0.4 2.7e-07 30.3 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH44132.1 - 5.2e-06 25.9 0.0 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH44132.1 - 1.3e-05 24.1 1.4 0.01 14.5 0.2 3.0 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KFH44132.1 - 0.00068 18.8 0.6 0.0034 16.5 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFH44132.1 - 0.0018 17.6 1.9 0.18 11.0 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KFH44132.1 - 0.0043 16.2 0.5 2 7.4 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFH44132.1 - 0.0049 17.1 0.4 0.03 14.6 0.4 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFH44132.1 - 0.033 13.4 0.0 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KFH44134.1 - 4.8e-23 81.6 0.0 8.9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH44134.1 - 5.1e-23 81.0 3.5 5.1e-23 81.0 3.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH44134.1 - 3.7e-06 28.0 0.0 5.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFH44134.1 - 0.00041 19.7 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFH44134.1 - 0.00054 19.4 0.6 0.00091 18.6 0.6 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 KFH44137.1 - 3.6e-22 78.3 16.6 2.6e-05 24.9 0.1 6.8 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44137.1 - 5.4e-11 42.6 4.8 0.0072 16.6 0.0 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFH44137.1 - 0.00044 20.2 8.9 0.15 12.0 0.3 4.0 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KFH44137.1 - 0.0098 14.9 0.0 7.1 5.5 0.0 3.5 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ndc80_HEC PF03801.13 KFH44139.1 - 1.7e-60 203.1 0.1 3.7e-60 202.0 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family TetR_C_1 PF02909.17 KFH44139.1 - 0.006 16.4 0.1 0.019 14.8 0.1 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Spc7 PF08317.11 KFH44139.1 - 0.0065 15.4 35.2 0.049 12.5 10.0 3.1 3 0 0 3 3 3 2 Spc7 kinetochore protein FliJ PF02050.16 KFH44139.1 - 0.026 14.7 29.3 0.078 13.2 7.3 3.4 3 2 1 4 4 3 0 Flagellar FliJ protein DUF1664 PF07889.12 KFH44139.1 - 0.031 14.3 0.4 0.031 14.3 0.4 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFH44139.1 - 0.044 13.8 43.2 0.082 13.0 15.8 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2935 PF11155.8 KFH44139.1 - 0.052 13.9 0.9 1.2 9.4 0.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Filament PF00038.21 KFH44139.1 - 0.053 13.1 40.9 0.097 12.2 17.1 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 KFH44139.1 - 0.083 13.4 17.4 0.061 13.8 5.6 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Phage_GP20 PF06810.11 KFH44139.1 - 0.19 11.6 23.6 0.021 14.6 3.0 4.2 2 1 2 4 4 4 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 KFH44139.1 - 0.53 9.7 44.0 0.5 9.8 15.8 3.7 2 2 2 4 4 4 0 Golgin subfamily A member 5 STAT_alpha PF01017.20 KFH44139.1 - 0.57 10.1 20.4 0.49 10.3 4.6 2.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain Snapin_Pallidin PF14712.6 KFH44139.1 - 1.8 9.1 17.2 0.13 12.7 3.7 3.2 3 0 0 3 3 3 0 Snapin/Pallidin DHR10 PF18595.1 KFH44139.1 - 2.1 8.4 44.9 0.019 15.0 16.0 4.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KFH44139.1 - 2.2 8.8 12.2 1.8 9.1 1.3 3.5 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KFH44139.1 - 4.9 6.5 38.3 2 7.7 12.2 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KFH44139.1 - 5 6.1 24.2 3.7 6.5 8.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4510 PF14971.6 KFH44139.1 - 6 7.2 10.1 0.42 10.9 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Prominin PF05478.11 KFH44139.1 - 7.4 4.4 14.9 0.27 9.2 4.5 2.1 2 0 0 2 2 2 0 Prominin DUF745 PF05335.13 KFH44139.1 - 8.1 6.1 22.0 4 7.1 6.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF745) APG6_N PF17675.1 KFH44139.1 - 8.4 6.9 49.6 26 5.3 21.0 4.6 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFH44139.1 - 8.7 5.6 28.5 3.2 7.0 4.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) RPW8 PF05659.11 KFH44139.1 - 9.3 5.9 16.7 2 8.1 5.2 3.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BCS1_N PF08740.11 KFH44140.1 - 2.3e-54 184.2 1.9 2.3e-54 184.2 1.9 2.2 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KFH44140.1 - 1e-16 61.6 0.0 2.4e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH44140.1 - 0.00062 19.8 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFH44140.1 - 0.0019 17.8 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TFIIF_alpha PF05793.12 KFH44140.1 - 0.0021 16.7 29.9 0.0021 16.7 29.9 2.2 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_16 PF13191.6 KFH44140.1 - 0.0046 17.3 0.7 0.013 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFH44140.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFH44140.1 - 0.032 13.2 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_11 PF13086.6 KFH44140.1 - 0.15 11.9 14.6 4.1 7.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KFH44140.1 - 0.54 10.0 3.5 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFH44140.1 - 0.73 10.4 4.0 5.7 7.5 0.0 3.2 3 0 0 3 3 3 0 ABC transporter DUF2828 PF11443.8 KFH44140.1 - 9.5 4.2 14.6 16 3.4 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RRM_1 PF00076.22 KFH44141.1 - 1.1e-22 79.5 0.0 2.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH44141.1 - 0.02 14.7 0.0 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif ketoacyl-synt PF00109.26 KFH44143.1 - 2.9e-75 253.1 0.1 7.4e-75 251.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH44143.1 - 1.2e-66 224.1 0.3 2.5e-66 223.0 0.3 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFH44143.1 - 1.3e-56 192.4 0.8 3e-56 191.2 0.8 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KFH44143.1 - 1.1e-47 162.7 0.0 1.8e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFH44143.1 - 4.1e-40 136.5 0.3 1.6e-39 134.6 0.1 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFH44143.1 - 9.8e-20 71.1 0.0 3.5e-19 69.3 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KFH44143.1 - 1.6e-15 58.4 0.0 4.6e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFH44143.1 - 8.8e-15 54.7 1.0 3.6e-14 52.7 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KFH44143.1 - 2.5e-14 53.4 0.7 1.3e-13 51.0 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KFH44143.1 - 4.9e-10 39.4 0.1 1.5e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KFH44143.1 - 4.2e-06 26.6 0.5 1.2e-05 25.1 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KFH44143.1 - 4.9e-06 26.8 0.1 1.4e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFH44143.1 - 9.7e-05 21.9 0.1 0.00022 20.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KFH44143.1 - 0.00046 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFH44143.1 - 0.00087 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 KFH44143.1 - 0.02 14.3 1.7 3.5 7.0 0.1 3.5 4 1 0 4 4 4 0 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 KFH44143.1 - 0.052 13.1 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 1 0 NmrA-like family ACP_syn_III PF08545.10 KFH44143.1 - 0.067 13.1 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III IQCJ-SCHIP1 PF15157.6 KFH44144.1 - 0.0018 18.1 0.6 0.0018 18.1 0.6 1.9 2 0 0 2 2 2 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif bZIP_1 PF00170.21 KFH44144.1 - 0.0024 17.9 7.7 0.0024 17.9 7.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFH44144.1 - 0.013 15.5 7.3 0.013 15.5 7.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Abhydrolase_3 PF07859.13 KFH44145.1 - 6.9e-45 153.5 0.0 2.7e-44 151.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH44145.1 - 0.001 18.0 0.0 0.0071 15.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase DUF4078 PF13300.6 KFH44147.1 - 2.3e-28 98.3 19.1 2.3e-28 98.3 19.1 3.6 3 2 0 3 3 3 1 Domain of unknown function (DUF4078) Pkinase PF00069.25 KFH44148.1 - 3.1e-71 239.9 0.0 5.3e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44148.1 - 2.7e-39 135.0 0.0 1.1e-38 133.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFH44148.1 - 2.5e-21 75.2 0.2 4.3e-21 74.5 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KFH44148.1 - 4.8e-07 29.1 0.0 7.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFH44148.1 - 5.3e-06 26.0 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFH44148.1 - 4.9e-05 22.8 0.1 9.3e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH44148.1 - 0.01 15.8 0.0 0.01 15.8 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFH44148.1 - 0.019 14.5 0.1 0.052 13.1 0.1 1.7 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFH44148.1 - 0.056 13.0 0.2 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FAD_binding_4 PF01565.23 KFH44149.1 - 2.2e-14 53.4 0.0 4.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MHC_II_alpha PF00993.20 KFH44149.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain p450 PF00067.22 KFH44150.1 - 2.7e-39 135.2 0.0 3.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GSDH PF07995.11 KFH44151.1 - 0.014 14.7 0.4 0.089 12.1 0.1 2.3 3 0 0 3 3 3 0 Glucose / Sorbosone dehydrogenase NHL PF01436.21 KFH44151.1 - 0.05 13.6 1.5 3.3 7.9 0.0 4.2 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 KFH44151.1 - 0.051 13.8 0.0 0.64 10.4 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller DUF3999 PF13163.6 KFH44152.1 - 0.018 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Transferase PF02458.15 KFH44153.1 - 8e-24 84.1 0.0 1.8e-23 82.9 0.0 1.5 1 1 0 1 1 1 1 Transferase family Sacchrp_dh_NADP PF03435.18 KFH44153.1 - 0.16 12.3 0.0 0.46 10.7 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pex14_N PF04695.13 KFH44155.1 - 8.8e-34 117.4 8.5 8.8e-34 117.4 8.5 3.5 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CR6_interact PF10147.9 KFH44155.1 - 0.00035 20.4 0.2 0.00053 19.8 0.2 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1043 PF06295.12 KFH44155.1 - 0.0019 18.2 2.3 0.0034 17.4 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Prominin PF05478.11 KFH44155.1 - 0.0027 15.7 1.1 0.0033 15.5 1.1 1.1 1 0 0 1 1 1 1 Prominin HLH PF00010.26 KFH44155.1 - 0.0037 17.2 0.2 3.8 7.6 0.1 3.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Golgin_A5 PF09787.9 KFH44155.1 - 0.008 15.7 6.1 0.013 15.0 6.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3584 PF12128.8 KFH44155.1 - 0.018 12.6 10.9 0.024 12.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HsbA PF12296.8 KFH44155.1 - 0.03 14.7 0.1 0.078 13.4 0.1 1.7 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Spc7 PF08317.11 KFH44155.1 - 0.039 12.8 5.6 0.058 12.3 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KFH44155.1 - 0.077 13.1 2.8 0.12 12.5 2.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 KFH44155.1 - 0.1 12.6 4.4 0.62 10.1 2.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 KFH44155.1 - 0.19 10.6 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 KFH44155.1 - 0.37 10.0 4.2 0.6 9.3 4.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 KFH44155.1 - 0.58 8.6 2.1 0.83 8.1 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PDE4_UCR PF18100.1 KFH44155.1 - 0.62 10.7 3.7 14 6.4 0.5 2.4 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Csm1_N PF18504.1 KFH44155.1 - 0.76 10.2 7.9 0.78 10.1 4.0 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FliE PF02049.18 KFH44155.1 - 0.94 9.7 4.4 6.5 7.0 1.2 2.5 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE CdvA PF18822.1 KFH44155.1 - 1.2 9.0 7.7 3.1 7.7 3.2 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 KFH44155.1 - 1.2 9.2 4.5 2.7 8.1 3.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KFH44155.1 - 1.3 8.4 4.2 2.2 7.6 4.2 1.4 1 0 0 1 1 1 0 FAM76 protein zf-C4H2 PF10146.9 KFH44155.1 - 1.6 9.0 11.2 0.075 13.3 5.0 1.9 2 1 0 2 2 1 0 Zinc finger-containing protein SYCE1 PF15233.6 KFH44155.1 - 1.8 8.6 8.7 2.8 8.0 8.7 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 NPV_P10 PF05531.12 KFH44155.1 - 2.4 8.7 6.5 1.9 9.0 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup88 PF10168.9 KFH44155.1 - 3 5.5 7.1 4.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Glyco_hydro_16 PF00722.21 KFH44156.1 - 3.1e-10 39.8 0.0 4.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.8 KFH44157.1 - 1.4e-11 43.8 0.1 1.7e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44157.1 - 9.4e-08 32.1 13.0 2e-07 31.0 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flu_M1_C PF08289.11 KFH44157.1 - 0.052 13.8 0.0 0.73 10.1 0.1 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain RRM_1 PF00076.22 KFH44159.1 - 2.8e-60 200.1 0.0 4.7e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH44159.1 - 1.8e-10 40.5 0.0 4.5e-06 26.3 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH44159.1 - 1.1e-08 34.8 0.0 0.025 14.4 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFH44159.1 - 5.2e-05 23.1 0.1 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KFH44159.1 - 0.00086 19.3 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KFH44159.1 - 0.0018 18.4 0.0 1 9.5 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif RRM_8 PF11835.8 KFH44159.1 - 0.0023 18.1 0.0 0.85 9.9 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RNA_bind PF08675.11 KFH44159.1 - 0.017 15.1 0.0 6.3 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain SET_assoc PF11767.8 KFH44159.1 - 0.07 12.8 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KFH44159.1 - 0.084 12.9 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 KFH44159.1 - 0.12 12.5 0.2 6.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Lipase_GDSL_2 PF13472.6 KFH44160.1 - 4.7e-09 36.9 0.0 9.9e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH44160.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ribosomal_L29e PF01779.17 KFH44161.1 - 5.3e-22 77.8 8.6 8.4e-22 77.2 8.6 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Cellulase PF00150.18 KFH44162.1 - 1.2e-13 51.1 0.2 2.3e-13 50.2 0.2 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RasGEF PF00617.19 KFH44163.1 - 2.6e-59 200.4 0.1 4.7e-59 199.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFH44163.1 - 7.6e-27 93.6 0.1 1.8e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFH44163.1 - 1.5e-15 56.5 0.1 3.6e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH44163.1 - 3.4e-14 52.4 0.2 8.3e-14 51.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH44163.1 - 4.7e-13 48.6 0.1 1.3e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KFH44163.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 WW domain RRM_1 PF00076.22 KFH44164.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 KFH44164.1 - 0.0047 17.2 0.5 0.0087 16.3 0.3 1.6 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding B-block_TFIIIC PF04182.12 KFH44164.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Zn_clus PF00172.18 KFH44165.1 - 2.6e-09 37.1 10.9 4.8e-09 36.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.19 KFH44166.1 - 2e-22 79.6 9.8 2e-22 79.6 9.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH44166.1 - 1.1e-18 67.8 0.0 6.5e-16 58.8 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH44166.1 - 4.1e-16 59.0 0.0 3.5e-14 52.8 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain zf-RING_UBOX PF13445.6 KFH44167.1 - 6.2e-08 32.5 9.1 3.1e-05 23.9 4.1 2.9 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KFH44167.1 - 3.1e-07 30.4 0.0 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 KFH44167.1 - 1.7e-06 27.7 11.1 0.00038 20.2 4.1 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH44167.1 - 1.7e-05 24.7 6.0 1.7e-05 24.7 6.0 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFH44167.1 - 2.1e-05 24.8 15.5 0.0051 17.1 8.4 3.1 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 KFH44167.1 - 2.6e-05 24.3 13.6 0.02 15.0 6.5 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.21 KFH44167.1 - 0.00014 21.9 9.9 0.00023 21.2 4.3 2.4 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4 PF00097.25 KFH44167.1 - 0.00021 21.1 12.8 0.0021 17.9 5.7 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 KFH44167.1 - 0.0022 18.2 1.2 0.0022 18.2 1.2 2.2 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Rtf2 PF04641.12 KFH44167.1 - 0.0099 15.3 1.5 0.0099 15.3 1.5 2.6 2 1 0 2 2 2 1 Rtf2 RING-finger BIR PF00653.21 KFH44167.1 - 0.044 14.4 1.9 11 6.8 0.1 3.0 1 1 2 3 3 3 0 Inhibitor of Apoptosis domain Herpes_US12 PF05363.12 KFH44167.1 - 0.096 13.4 0.0 0.096 13.4 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus US12 family zf-RING_6 PF14835.6 KFH44167.1 - 1.5 8.8 8.7 2.1 8.3 0.9 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFH44167.1 - 2.2 8.5 13.1 0.15 12.2 3.6 2.7 3 0 0 3 3 3 0 zinc RING finger of MSL2 DZR PF12773.7 KFH44167.1 - 4.4 7.4 15.5 3.2 7.8 7.2 3.4 2 1 0 2 2 2 0 Double zinc ribbon CTU2 PF10288.9 KFH44168.1 - 7.9e-10 39.0 0.0 4e-08 33.5 0.0 2.5 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 KFH44168.1 - 0.022 14.8 3.3 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 KFH44169.1 - 3.8e-50 170.7 0.0 1e-49 169.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44169.1 - 2.9e-23 82.5 0.0 5.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH44169.1 - 0.00034 20.6 0.1 0.00034 20.6 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFH44169.1 - 0.0034 17.0 0.2 0.0092 15.6 0.2 1.6 1 1 0 1 1 1 1 RIO1 family SRP9-21 PF05486.12 KFH44170.1 - 5.7e-23 81.1 0.0 7.8e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) EamA PF00892.20 KFH44171.1 - 3.9e-08 33.6 22.3 0.00022 21.4 4.1 3.1 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KFH44171.1 - 3.9e-08 32.8 0.0 6.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KFH44171.1 - 9.9e-05 21.8 0.2 9.9e-05 21.8 0.2 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF2613 PF11021.8 KFH44171.1 - 0.041 14.0 3.6 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Trp_oprn_chp PF09534.10 KFH44171.1 - 1.9 8.2 11.7 0.54 10.0 7.3 2.1 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mito_carr PF00153.27 KFH44172.1 - 9e-47 157.0 4.0 1.2e-16 60.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DCP2 PF05026.13 KFH44173.1 - 2.6e-31 107.7 0.7 4.7e-31 106.9 0.7 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KFH44173.1 - 2.3e-15 56.8 0.0 4.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Forkhead PF00250.18 KFH44174.1 - 9.6e-32 109.1 0.3 2e-31 108.1 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFH44174.1 - 8.6e-09 35.6 0.1 2.2e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFH44174.1 - 0.00045 20.5 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Acyltransferase PF01553.21 KFH44175.1 - 4.7e-14 52.2 0.0 6.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase FYRN PF05964.14 KFH44175.1 - 0.29 11.0 0.6 0.85 9.5 0.1 2.0 3 0 0 3 3 3 0 F/Y-rich N-terminus Yippee-Mis18 PF03226.14 KFH44177.1 - 8.4e-16 58.1 0.1 9.5e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 KFH44177.1 - 0.0039 17.0 0.2 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease RIG-I_C-RD PF11648.8 KFH44177.1 - 0.004 17.4 0.2 0.006 16.8 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I Endonuclease_7 PF02945.15 KFH44177.1 - 0.0049 16.8 1.2 0.011 15.6 1.2 1.6 1 1 0 1 1 1 1 Recombination endonuclease VII DUF1247 PF06851.11 KFH44177.1 - 0.02 14.8 0.6 0.058 13.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) DUF2039 PF10217.9 KFH44177.1 - 0.039 14.3 0.6 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) OTT_1508_deam PF14441.6 KFH44177.1 - 0.073 13.1 0.8 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 OTT_1508-like deaminase WD40 PF00400.32 KFH44178.1 - 5.3e-17 61.9 4.9 1e-08 35.6 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44178.1 - 5.7e-05 23.3 0.0 0.71 10.2 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFH44178.1 - 0.032 13.0 0.2 0.27 9.9 0.1 2.1 2 1 1 3 3 3 0 Nup133 N terminal like Methyltransf_28 PF02636.17 KFH44179.1 - 1e-82 277.7 0.0 1.3e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_S28e PF01200.18 KFH44179.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S28e DUF4112 PF13430.6 KFH44180.1 - 1.6e-34 118.3 1.1 2e-34 118.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) zf-C2H2 PF00096.26 KFH44181.1 - 1.1e-07 31.9 10.1 0.0055 17.1 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH44181.1 - 0.0037 17.6 8.4 6.1 7.5 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH44181.1 - 0.012 16.4 9.5 0.11 13.4 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFH44181.1 - 0.38 11.1 7.1 0.41 11.0 0.8 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_64 PF16483.5 KFH44182.1 - 9.6e-128 426.5 0.0 1.1e-127 426.3 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase PPR_2 PF13041.6 KFH44183.1 - 1e-23 83.2 0.1 7.2e-17 61.3 0.0 3.5 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KFH44183.1 - 1.8e-10 40.7 0.1 4.5e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFH44183.1 - 1.4e-08 34.3 0.3 1.6e-06 27.7 0.1 3.3 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFH44183.1 - 2.1e-06 27.6 1.3 0.041 14.1 0.0 5.6 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.7 KFH44183.1 - 0.00032 20.3 0.3 21 4.9 0.0 4.5 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.7 KFH44183.1 - 0.097 12.5 0.1 3 7.8 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ATPase expression Pro_isomerase PF00160.21 KFH44184.1 - 7.6e-48 162.8 0.0 1.3e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KFH44184.1 - 0.00016 21.8 0.1 0.00087 19.4 0.0 2.3 3 0 0 3 3 3 1 U-box domain zf-NOSIP PF15906.5 KFH44184.1 - 0.0072 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein HZS_alpha PF18582.1 KFH44184.1 - 0.12 12.9 0.1 0.32 11.5 0.1 1.7 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain PAP_central PF04928.17 KFH44186.1 - 1.2e-110 368.3 0.0 2e-110 367.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFH44186.1 - 6.7e-61 204.9 1.0 2.5e-59 199.7 1.0 2.7 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFH44186.1 - 3.4e-10 40.1 0.0 7.9e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KFH44186.1 - 0.019 14.8 0.1 0.12 12.2 0.2 2.1 3 0 0 3 3 3 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 KFH44186.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase TM1586_NiRdase PF14512.6 KFH44186.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase Ribonuc_red_sm PF00268.21 KFH44187.1 - 4.6e-121 403.5 3.9 5.9e-121 403.2 3.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Fungal_trans PF04082.18 KFH44189.1 - 2.3e-16 59.6 1.1 3.8e-16 58.9 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFH44189.1 - 8e-07 29.2 13.3 7.7e-05 22.9 5.5 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFH44189.1 - 0.007 16.8 16.7 0.27 11.8 7.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFH44189.1 - 0.045 14.4 1.0 1.8 9.3 0.1 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-CHY PF05495.12 KFH44189.1 - 1.4 9.5 6.4 0.81 10.2 3.5 1.9 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_4 PF13894.6 KFH44189.1 - 2 9.5 21.6 0.82 10.7 1.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.27 KFH44190.1 - 5.3e-54 180.1 2.0 3.1e-19 68.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.29 KFH44191.1 - 2e-25 89.3 0.2 3e-13 50.2 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFH44191.1 - 7e-14 52.1 2.2 2.7e-06 27.8 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFH44191.1 - 3.5e-08 33.8 1.0 0.00035 20.9 0.2 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KFH44191.1 - 0.00083 19.4 0.0 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFH44191.1 - 0.00083 19.6 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFH44191.1 - 0.086 12.7 1.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Thx PF17070.5 KFH44191.1 - 0.15 12.2 6.5 0.15 12.2 1.6 2.6 2 0 0 2 2 2 0 30S ribosomal protein Thx SCA7 PF08313.12 KFH44192.1 - 2.4e-32 110.6 0.2 6.5e-32 109.2 0.2 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain Omega-toxin PF06357.11 KFH44192.1 - 0.14 12.0 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Omega-atracotoxin CDC45 PF02724.14 KFH44192.1 - 0.6 8.3 11.3 0.75 8.0 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KFH44192.1 - 1.2 9.2 12.8 1.5 8.9 10.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PBP_sp32 PF07222.12 KFH44192.1 - 3.6 7.0 9.0 0.9 9.0 5.3 1.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF2985 PF11204.8 KFH44193.1 - 6.9e-21 74.2 0.1 6.9e-21 74.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) SurA_N_3 PF13624.6 KFH44193.1 - 0.066 13.0 0.2 0.16 11.8 0.0 1.7 1 1 1 2 2 2 0 SurA N-terminal domain Cytochrom_B_N_2 PF13631.6 KFH44193.1 - 0.084 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SAM_2 PF07647.17 KFH44194.1 - 1.6e-09 37.7 0.1 2.9e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFH44194.1 - 1.6e-05 25.2 0.2 3.2e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFH44194.1 - 0.053 13.6 0.3 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 KFH44194.1 - 0.14 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Tubulin_3 PF14881.6 KFH44195.1 - 1.5e-72 243.1 0.1 2.7e-72 242.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KFH44195.1 - 2.1e-24 86.1 0.0 4.8e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KFH44195.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Mito_carr PF00153.27 KFH44196.1 - 6.7e-55 183.0 1.8 4.9e-18 64.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.6 KFH44197.1 - 9.8e-10 38.6 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFH44197.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF713 PF05218.14 KFH44197.1 - 0.29 10.8 0.0 0.39 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) K_oxygenase PF13434.6 KFH44198.1 - 0.038 13.1 0.1 0.054 12.6 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.25 KFH44199.1 - 1.2e-58 198.5 0.0 1.7e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44199.1 - 8.6e-26 90.8 0.0 1.6e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH44199.1 - 0.001 18.5 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFH44199.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ELYS-bb PF16687.5 KFH44199.1 - 0.035 12.7 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin APH PF01636.23 KFH44199.1 - 1.5 8.7 6.8 2.4 8.0 4.7 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family FYDLN_acid PF09538.10 KFH44199.1 - 4.5 8.0 16.1 9 7.0 16.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4887 PF16228.5 KFH44199.1 - 6 7.0 16.6 2.1 8.5 13.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) Nop14 PF04147.12 KFH44199.1 - 9.6 4.3 17.9 12 4.0 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family CLU PF13236.6 KFH44200.1 - 5.7e-77 258.5 0.0 9.6e-77 257.7 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KFH44200.1 - 4.7e-53 179.8 0.0 1.2e-52 178.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFH44200.1 - 4.8e-28 97.3 10.2 3.8e-12 46.3 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH44200.1 - 2.2e-22 78.2 8.6 7.6e-07 28.8 0.1 5.6 5 2 1 6 6 6 3 Tetratricopeptide repeat CLU_N PF15044.6 KFH44200.1 - 1.7e-20 73.2 0.0 3.7e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 KFH44200.1 - 5.8e-05 23.0 8.0 0.0014 18.7 0.2 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 KFH44200.1 - 0.0015 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) ubiquitin PF00240.23 KFH44200.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family TPR_2 PF07719.17 KFH44200.1 - 0.015 15.4 0.2 0.015 15.4 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFH44200.1 - 3.8 8.1 7.1 66 4.2 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Septin PF00735.18 KFH44201.1 - 7.7e-13 48.3 0.1 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_16 PF13191.6 KFH44201.1 - 0.00015 22.2 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFH44201.1 - 0.03 14.2 0.1 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KFH44201.1 - 0.036 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFH44201.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KFH44201.1 - 0.096 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KFH44201.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KFH44201.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFH44201.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KFH44201.1 - 0.17 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KFH44201.1 - 0.19 11.5 1.1 0.52 10.1 0.1 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Lung_7-TM_R PF06814.13 KFH44202.1 - 4.5e-70 236.2 14.2 5.5e-70 235.9 14.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4492 PF14899.6 KFH44202.1 - 0.046 13.6 0.2 0.21 11.5 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF4131 PF13567.6 KFH44202.1 - 3.5 7.2 11.5 0.46 10.1 2.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Sen15 PF09631.10 KFH44203.1 - 6.1e-26 90.6 0.0 7.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Pkinase PF00069.25 KFH44204.1 - 1.3e-77 260.7 0.0 1.7e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44204.1 - 4.1e-38 131.1 0.0 6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH44204.1 - 0.0034 16.4 0.0 0.03 13.3 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Peptidase_C2 PF00648.21 KFH44205.1 - 1.1e-28 100.2 0.0 1.6e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFH44205.1 - 4.4e-09 36.7 0.1 1.5e-07 31.8 0.0 2.6 2 1 0 2 2 2 1 Calpain large subunit, domain III adh_short_C2 PF13561.6 KFH44206.1 - 6.5e-65 218.9 0.3 7.3e-65 218.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH44206.1 - 2.1e-51 174.2 0.4 2.6e-51 173.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH44206.1 - 2.1e-13 50.6 1.3 3.3e-13 49.9 1.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH44206.1 - 0.004 17.0 0.7 0.0063 16.4 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KFH44206.1 - 0.13 12.4 0.7 1.2 9.3 0.7 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 KFH44208.1 - 2.3e-27 95.8 40.9 3.1e-27 95.4 40.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DDHD PF02862.17 KFH44209.1 - 5.8e-23 82.2 0.2 7.8e-20 72.0 0.0 2.9 2 1 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 KFH44209.1 - 0.22 11.1 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SOG2 PF10428.9 KFH44209.1 - 0.24 10.6 2.4 0.35 10.0 2.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SH3_3 PF08239.11 KFH44210.1 - 8.5e-05 22.8 0.2 0.0002 21.6 0.2 1.6 1 1 0 1 1 1 1 Bacterial SH3 domain Say1_Mug180 PF10340.9 KFH44211.1 - 5.9e-25 87.9 0.0 8.2e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KFH44211.1 - 5.4e-24 85.2 0.2 6.7e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KFH44211.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 KFH44211.1 - 0.098 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase COesterase PF00135.28 KFH44211.1 - 0.12 11.3 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Lipase PF00151.19 KFH44211.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Lipase Abhydrolase_2 PF02230.16 KFH44211.1 - 0.19 11.5 0.1 0.86 9.4 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mus7 PF09462.10 KFH44212.1 - 2.5e-133 446.1 0.0 3.4e-133 445.7 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Peptidase_C48 PF02902.19 KFH44213.1 - 1.1e-19 71.1 0.0 2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3886 PF13025.6 KFH44213.1 - 9.5 6.5 15.7 37 4.6 15.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) PTR2 PF00854.21 KFH44214.1 - 4.4e-30 104.8 3.8 6.4e-28 97.7 0.2 2.1 1 1 1 2 2 2 2 POT family DUF2530 PF10745.9 KFH44214.1 - 0.065 13.5 0.2 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Peptidase_S8 PF00082.22 KFH44216.1 - 3.6e-30 105.2 17.7 9.7e-30 103.8 17.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH44216.1 - 7.7e-19 68.2 0.1 1.4e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zn_clus PF00172.18 KFH44217.1 - 3.9e-09 36.5 8.6 6.9e-09 35.7 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH44217.1 - 6.5e-07 28.5 0.0 3.4e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain TDA11 PF17084.5 KFH44218.1 - 4.8 6.0 9.3 8.4 5.2 9.3 1.4 1 1 0 1 1 1 0 Topoisomerase I damage affected protein 11 DUF3712 PF12505.8 KFH44220.1 - 6.8e-24 84.5 0.0 1.3e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ATP-synt_ab PF00006.25 KFH44221.1 - 8.3e-61 205.3 0.0 1.3e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFH44221.1 - 8.7e-23 80.6 0.4 2.6e-22 79.1 0.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 KFH44221.1 - 0.017 15.0 0.8 0.087 12.7 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NB-ARC PF00931.22 KFH44221.1 - 0.017 14.3 0.2 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KFH44221.1 - 0.023 14.6 0.3 0.054 13.4 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 KFH44221.1 - 0.042 14.2 0.6 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFH44221.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KFH44221.1 - 0.06 13.8 0.3 5 7.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH44221.1 - 0.078 13.2 0.2 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFH44221.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KFH44221.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KFH44221.1 - 0.092 12.1 0.4 0.17 11.2 0.4 1.4 1 0 0 1 1 1 0 KaiC Cupin_8 PF13621.6 KFH44222.1 - 1e-30 107.3 0.0 1.6e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KFH44222.1 - 3.4e-13 50.0 0.0 1.5e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KFH44222.1 - 1.1e-06 28.6 0.0 2.2e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KFH44222.1 - 0.0017 18.3 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KFH44222.1 - 0.0026 18.0 1.5 0.71 10.2 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Cupin_4 PF08007.12 KFH44222.1 - 0.0027 17.2 0.1 0.0048 16.4 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.6 KFH44222.1 - 0.084 13.2 2.9 1.6 9.2 0.1 3.7 4 0 0 4 4 4 0 Kelch motif COX4 PF02936.14 KFH44223.1 - 2.4e-47 160.4 0.1 2.8e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KFH44223.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DSPc PF00782.20 KFH44224.1 - 6e-24 84.4 0.0 2.8e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFH44224.1 - 0.0025 17.4 0.1 0.0091 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pyr_redox_3 PF13738.6 KFH44225.1 - 2.5e-10 40.1 0.0 1.2e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFH44225.1 - 1.9e-09 36.5 0.0 3.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH44225.1 - 1.2e-08 35.0 0.0 1.3e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH44225.1 - 3.9e-06 26.3 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KFH44225.1 - 1.6e-05 24.3 0.0 8e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH44225.1 - 9.8e-05 21.6 0.0 0.0014 17.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFH44225.1 - 0.00021 21.0 0.2 0.0078 15.8 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFH44225.1 - 0.00057 20.4 0.0 0.24 12.0 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH44225.1 - 0.047 13.7 0.3 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFH44225.1 - 0.056 12.5 0.1 0.45 9.5 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 KFH44225.1 - 0.16 12.1 0.0 0.88 9.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KFH44225.1 - 0.17 10.9 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AAA_2 PF07724.14 KFH44226.1 - 7.1e-33 114.1 0.0 2.3e-32 112.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFH44226.1 - 4e-13 49.9 0.3 8.3e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFH44226.1 - 8.7e-09 35.3 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFH44226.1 - 2.2e-07 30.9 0.0 6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KFH44226.1 - 5.4e-05 22.4 0.0 0.00014 21.0 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 KFH44226.1 - 0.00062 20.0 1.9 0.0026 18.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFH44226.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFH44226.1 - 0.0022 18.4 0.0 0.014 15.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KFH44226.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFH44226.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KFH44226.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KFH44226.1 - 0.044 14.3 0.6 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFH44226.1 - 0.046 13.1 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KFH44226.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFH44226.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFH44226.1 - 0.1 12.9 0.1 0.29 11.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFH44226.1 - 0.18 12.3 0.9 0.25 11.8 0.1 1.7 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.6 KFH44226.1 - 0.22 11.3 1.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFH44227.1 - 1.1e-38 132.7 0.0 2.3e-37 128.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH44227.1 - 4.4e-09 36.0 0.0 9.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFH44227.1 - 5.5e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH44227.1 - 3.9e-05 24.1 0.1 0.002 18.5 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFH44227.1 - 9e-05 22.7 0.0 0.023 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH44227.1 - 0.00012 22.4 0.3 0.044 14.0 0.1 3.0 2 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFH44227.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFH44227.1 - 0.0041 17.1 0.1 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFH44227.1 - 0.0055 16.1 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFH44227.1 - 0.0074 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KFH44227.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFH44227.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KFH44227.1 - 0.019 15.5 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFH44227.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KFH44227.1 - 0.036 13.7 0.9 0.67 9.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KFH44227.1 - 0.052 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KFH44227.1 - 0.06 12.8 0.0 1.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 KFH44227.1 - 0.097 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KFH44227.1 - 0.17 11.8 0.1 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFH44227.1 - 0.18 12.4 0.0 0.66 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KFH44227.1 - 0.27 10.5 0.5 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Transket_pyr PF02779.24 KFH44228.1 - 1.1e-61 207.6 0.0 1.8e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFH44228.1 - 8.9e-57 192.3 0.0 1.2e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFH44228.1 - 2e-54 183.4 0.0 3.2e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFH44228.1 - 9.6e-20 69.9 1.2 2.3e-19 68.7 1.2 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus MFS_1 PF07690.16 KFH44229.1 - 2.9e-23 82.4 72.2 1.1e-17 64.0 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KFH44231.1 - 5.9e-40 136.8 0.0 1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH44231.1 - 2.9e-28 99.0 0.0 1e-27 97.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH44231.1 - 1.3e-11 44.8 0.5 6e-11 42.6 0.5 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KFH44231.1 - 5.5e-05 22.3 0.1 8.4e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH44231.1 - 0.00096 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KFH44231.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFH44231.1 - 0.018 14.9 0.1 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding DUF1776 PF08643.10 KFH44231.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) EthD PF07110.11 KFH44232.1 - 7.3e-23 81.5 0.0 2.9e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 EthD domain MmlI PF09448.10 KFH44232.1 - 1.9e-07 31.5 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DEAD_2 PF06733.15 KFH44233.1 - 5.7e-55 185.6 0.2 5.7e-55 185.6 0.2 1.6 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KFH44233.1 - 2.2e-48 164.5 1.6 9.2e-45 152.7 0.5 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KFH44233.1 - 7.8e-44 149.8 0.0 2.5e-43 148.2 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KFH44233.1 - 0.00029 20.9 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH44233.1 - 0.0032 17.3 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFH44233.1 - 0.0037 16.1 0.0 0.034 12.9 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.16 KFH44233.1 - 0.15 11.5 0.1 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF1996 PF09362.10 KFH44234.1 - 3.1e-83 279.4 0.4 3.9e-83 279.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PTR2 PF00854.21 KFH44235.1 - 6e-08 31.9 0.1 7.1e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 POT family zf-H2C2 PF09337.10 KFH44235.1 - 0.12 12.6 0.3 2.1 8.6 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger p450 PF00067.22 KFH44236.1 - 5.5e-78 262.8 0.0 6.9e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_assoc_2 PF16193.5 KFH44236.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain 7tm_1 PF00001.21 KFH44238.1 - 1.7e-10 40.7 5.6 2.9e-10 39.9 5.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KFH44238.1 - 1.2e-09 37.9 9.2 1.8e-09 37.3 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFH44238.1 - 5.2e-08 32.4 9.4 9.3e-08 31.5 9.4 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KFH44238.1 - 4.9e-06 26.5 11.3 1.1e-05 25.4 11.3 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KFH44238.1 - 0.0012 18.3 8.0 0.0017 17.8 8.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KFH44238.1 - 0.023 13.8 11.3 0.14 11.1 4.9 2.2 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region FAD_binding_3 PF01494.19 KFH44239.1 - 4.5e-74 249.8 0.0 6.7e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFH44239.1 - 3e-36 125.0 0.1 5.1e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KFH44239.1 - 0.00029 20.2 0.0 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH44239.1 - 0.0016 19.0 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH44239.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH44239.1 - 0.027 14.1 0.1 0.64 9.5 0.0 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.6 KFH44239.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 KFH44239.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.25 KFH44240.1 - 4.3e-29 101.7 0.0 1.1e-28 100.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44240.1 - 1.8e-09 37.3 0.1 2.7e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.23 KFH44241.1 - 1.6e-24 86.2 6.3 6.5e-24 84.3 6.5 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KFH44241.1 - 9.8e-12 44.8 0.1 1.8e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like RGS PF00615.19 KFH44242.1 - 7.5e-11 42.3 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Abhydrolase_3 PF07859.13 KFH44243.1 - 4.8e-25 88.7 0.1 6.1e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH44243.1 - 4.2e-09 35.8 0.0 8e-09 34.8 0.0 1.4 2 0 0 2 2 2 1 Steryl acetyl hydrolase DUF948 PF06103.11 KFH44244.1 - 7.1e-05 23.0 9.6 24 5.2 0.0 8.2 7 2 1 8 8 8 1 Bacterial protein of unknown function (DUF948) DHC_N1 PF08385.12 KFH44244.1 - 0.00034 19.4 0.2 0.24 10.0 0.0 2.6 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF4197 PF13852.6 KFH44244.1 - 0.015 15.0 0.0 1.1 8.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4197) Glutaredoxin2_C PF04399.13 KFH44244.1 - 0.042 13.7 5.7 32 4.4 0.1 5.1 5 0 0 5 5 5 0 Glutaredoxin 2, C terminal domain IL31 PF15209.6 KFH44244.1 - 0.062 13.1 0.1 16 5.2 0.0 3.3 2 0 0 2 2 2 0 Interleukin 31 DUF4175 PF13779.6 KFH44244.1 - 0.095 10.6 1.5 0.13 10.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AI-2E_transport PF01594.16 KFH44244.1 - 0.16 11.1 0.3 13 4.8 0.0 3.1 2 1 2 4 4 4 0 AI-2E family transporter DAO PF01266.24 KFH44246.1 - 4.5e-53 181.1 0.0 6.5e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFH44246.1 - 7.4e-44 148.7 0.1 1.2e-43 147.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KFH44246.1 - 2.5e-07 30.1 0.5 7.3e-07 28.6 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFH44246.1 - 0.0009 18.7 4.6 0.0032 16.9 4.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH44246.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH44246.1 - 0.0087 16.3 0.2 0.033 14.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFH44246.1 - 0.025 13.8 1.0 0.27 10.4 1.0 2.2 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KFH44246.1 - 0.032 13.3 0.1 0.072 12.2 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFH44246.1 - 0.035 12.8 0.3 0.055 12.2 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KFH44246.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFH44246.1 - 0.097 13.2 0.2 0.37 11.4 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH44246.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO PF00650.20 KFH44247.1 - 1.1e-40 139.0 0.0 2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH44247.1 - 1.6e-14 53.8 0.8 7e-14 51.8 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFH44247.1 - 8.7e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2236 PF09995.9 KFH44247.1 - 0.017 15.3 0.5 0.073 13.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) CUE PF02845.16 KFH44247.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 CUE domain DUF3189 PF11385.8 KFH44247.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) MFS_1 PF07690.16 KFH44248.1 - 4.1e-48 164.1 35.0 4.1e-48 164.1 35.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH44248.1 - 9.1e-16 57.7 11.3 9.1e-16 57.7 11.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KFH44248.1 - 2e-07 30.7 3.7 2e-07 30.7 3.7 2.2 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 KFH44248.1 - 0.0039 15.5 2.6 0.12 10.6 0.0 2.3 2 0 0 2 2 2 2 BT1 family Far-17a_AIG1 PF04750.14 KFH44248.1 - 0.039 13.3 0.5 0.039 13.3 0.5 2.0 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein PTR2 PF00854.21 KFH44248.1 - 0.048 12.5 0.1 0.048 12.5 0.1 2.6 3 1 1 4 4 4 0 POT family ANAPC4_WD40 PF12894.7 KFH44249.1 - 0.00019 21.7 0.0 0.72 10.2 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFH44249.1 - 0.0049 17.7 0.3 1.7 9.7 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KFH44249.1 - 0.045 12.8 0.0 0.61 9.1 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Alpha-amylase_C PF02806.18 KFH44250.1 - 1.2e-28 99.4 0.1 2.7e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KFH44250.1 - 1e-16 61.1 0.0 3.6e-16 59.3 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFH44250.1 - 2.2e-15 57.1 0.4 3.4e-12 46.6 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFH44250.1 - 0.049 12.7 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Zn_clus PF00172.18 KFH44252.1 - 1.6e-07 31.3 13.8 1.6e-07 31.3 13.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH44252.1 - 0.00036 19.5 0.1 0.0005 19.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BSD PF03909.17 KFH44253.1 - 1.6e-30 104.9 5.9 2.8e-15 56.1 0.1 3.2 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KFH44253.1 - 1.7e-27 95.5 0.0 4.1e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Cas_APE2256 PF09651.10 KFH44253.1 - 0.18 11.7 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) WD40 PF00400.32 KFH44254.1 - 1.6e-24 85.7 16.1 1.9e-07 31.7 0.3 7.2 6 2 1 7 7 7 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFH44254.1 - 0.012 14.6 0.1 0.47 9.4 0.2 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rick_17kDa_Anti PF05433.15 KFH44255.1 - 7e-05 22.6 4.2 0.14 12.1 0.2 2.2 2 0 0 2 2 2 2 Glycine zipper 2TM domain PQ-loop PF04193.14 KFH44256.1 - 2.8e-17 62.2 2.3 2.2e-11 43.4 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat WSC PF01822.19 KFH44257.1 - 2.3e-12 46.9 6.0 2.3e-12 46.9 6.0 1.9 2 0 0 2 2 2 1 WSC domain Glyco_hydro_18 PF00704.28 KFH44258.1 - 3.2e-50 171.7 3.0 5.2e-50 170.9 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFH44258.1 - 1.4e-16 60.2 0.0 6e-07 29.4 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.19 KFH44258.1 - 2.9e-05 24.5 8.1 2.9e-05 24.5 8.1 4.9 4 0 0 4 4 4 1 Chitin recognition protein DUF4244 PF14029.6 KFH44258.1 - 2.5 7.6 4.5 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) TRP PF06011.12 KFH44259.1 - 0.006 15.4 2.1 0.011 14.4 2.1 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel STE2 PF02116.15 KFH44259.1 - 0.054 12.8 11.2 0.058 12.7 9.2 1.9 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR Fungal_trans PF04082.18 KFH44261.1 - 3e-11 42.9 0.0 1.2e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44261.1 - 2.2e-07 30.9 11.6 3.7e-07 30.2 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 KFH44262.1 - 9.3e-78 262.1 0.1 1.1e-77 261.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_11 PF14833.6 KFH44263.1 - 3.4e-38 130.6 0.1 1.7e-26 92.8 0.0 2.9 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KFH44263.1 - 1.2e-35 123.0 0.1 2e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFH44263.1 - 0.00029 21.3 0.0 0.0022 18.5 0.0 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFH44263.1 - 0.00032 20.6 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFH44263.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ribosomal_L22 PF00237.19 KFH44263.1 - 0.19 12.0 0.0 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Glyco_hydro_1 PF00232.18 KFH44264.1 - 1.9e-150 501.3 0.0 2.2e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 KFH44264.1 - 0.0031 17.1 0.0 0.0076 15.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.24 KFH44265.1 - 8.6e-110 367.7 16.0 1e-109 367.4 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH44265.1 - 4.3e-20 71.9 40.4 1.9e-16 60.0 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.18 KFH44266.1 - 4e-45 154.2 31.4 4.6e-45 154.0 31.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KFH44266.1 - 0.58 10.0 6.3 0.19 11.6 0.7 3.2 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PLDc_2 PF13091.6 KFH44268.1 - 1e-18 67.5 0.0 5.5e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Pept_S41_N PF18294.1 KFH44268.1 - 1.7 8.7 4.6 0.52 10.4 1.2 1.9 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain PQ-loop PF04193.14 KFH44269.1 - 5.4e-31 106.2 8.3 1.6e-15 56.6 3.9 2.5 2 0 0 2 2 2 2 PQ loop repeat TrbE PF11100.8 KFH44269.1 - 0.089 13.0 0.9 19 5.6 0.3 2.7 2 1 0 2 2 2 0 Conjugal transfer protein TrbE Cyt-b5 PF00173.28 KFH44270.1 - 2.1e-13 50.2 0.0 4.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KFH44270.1 - 1.9e-10 40.1 0.0 8.4e-10 38.0 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KFH44270.1 - 1.1e-08 34.9 0.0 6.2e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFH44270.1 - 1.2e-07 32.3 0.0 2.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Dynamin_N PF00350.23 KFH44271.1 - 0.051 13.6 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin family DUF1488 PF07369.11 KFH44271.1 - 0.19 11.7 0.1 0.61 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DUF3357 PF11837.8 KFH44274.1 - 0.045 14.2 0.3 0.23 11.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) CwfJ_C_2 PF04676.14 KFH44275.1 - 8e-26 90.8 0.0 8e-26 90.8 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KFH44275.1 - 2.3e-25 88.8 0.0 3.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Zn_clus PF00172.18 KFH44276.1 - 5e-08 32.9 9.4 1.2e-07 31.7 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH44276.1 - 0.00025 20.0 0.0 0.00062 18.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3808 PF10300.9 KFH44277.1 - 2.2e-116 389.4 0.0 3e-116 389.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KFH44277.1 - 0.0046 17.4 0.2 3.2 8.3 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat HNF-1_N PF04814.13 KFH44277.1 - 1 9.9 3.2 3.5 8.2 3.2 1.9 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus TPR_6 PF13174.6 KFH44277.1 - 1.8 9.4 6.0 57 4.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH44277.1 - 2.9 8.1 5.1 2.1 8.6 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KFH44278.1 - 0.00053 20.2 0.0 0.0024 18.1 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH44278.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mpv17_PMP22 PF04117.12 KFH44279.1 - 7.3e-20 71.0 0.1 7.3e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family IDO PF01231.18 KFH44280.1 - 2.9e-116 388.8 0.0 3.6e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KFH44280.1 - 0.039 12.7 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) peroxidase PF00141.23 KFH44281.1 - 7.1e-85 284.3 0.0 1.6e-45 155.6 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Ntox17 PF15524.6 KFH44281.1 - 0.073 13.4 0.5 0.4 11.0 0.1 2.4 2 0 0 2 2 2 0 Novel toxin 17 tRNA-synt_1 PF00133.22 KFH44282.1 - 5.9e-51 173.4 0.0 1.1e-29 103.2 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFH44282.1 - 1.6e-42 145.2 0.0 3.2e-42 144.2 0.0 1.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KFH44282.1 - 6.6e-32 110.7 0.0 2.2e-21 76.1 0.0 4.9 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFH44282.1 - 5.6e-11 42.6 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFH44282.1 - 0.012 15.0 0.0 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 KFH44282.1 - 0.12 11.8 3.0 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFH44282.1 - 0.49 10.6 2.1 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Cyclin_N PF00134.23 KFH44283.1 - 7.8e-43 145.2 0.0 1.6e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFH44283.1 - 9.8e-38 128.9 0.2 2.3e-37 127.7 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIA PF03153.13 KFH44283.1 - 2.4 8.0 11.5 3.5 7.5 11.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_WhiA PF02650.14 KFH44284.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DUF4611 PF15387.6 KFH44284.1 - 2.1 8.6 5.5 4.7 7.5 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase_fungal PF17667.1 KFH44285.1 - 8.6e-108 360.7 0.0 1.1e-107 360.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFH44285.1 - 0.00056 19.4 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFH44285.1 - 0.047 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFH44285.1 - 0.082 12.5 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DNA_meth_N PF18284.1 KFH44286.1 - 2.3 8.2 3.7 3.1 7.8 1.0 2.4 2 0 0 2 2 2 0 DNA methylase N-terminal domain TFIIB PF00382.19 KFH44288.1 - 5.1e-30 103.3 0.6 8.3e-19 67.4 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KFH44288.1 - 3.1e-24 85.3 0.7 3.1e-24 85.3 0.7 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KFH44288.1 - 3.8e-05 23.4 1.0 0.021 14.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Sugar_tr PF00083.24 KFH44290.1 - 1.6e-75 254.7 19.5 1.9e-75 254.5 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH44290.1 - 3.4e-27 95.3 32.3 4.6e-21 75.1 7.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH44290.1 - 1.6e-06 26.9 1.1 1.6e-06 26.9 1.1 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ACT_3 PF10000.9 KFH44291.1 - 2.3e-25 88.3 0.0 3.7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KFH44291.1 - 3.5e-08 33.1 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ACT domain Cerato-platanin PF07249.12 KFH44292.1 - 0.00041 20.4 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin OTT_1508_deam PF14441.6 KFH44293.1 - 3.6e-12 46.1 0.8 1.8e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 OTT_1508-like deaminase zf-MYND PF01753.18 KFH44293.1 - 0.0041 17.2 16.6 0.0089 16.1 16.6 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KFH44293.1 - 4.7 7.6 10.4 11 6.4 10.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DPPIV_N PF00930.21 KFH44294.1 - 9.5e-104 346.9 1.8 1.3e-103 346.5 1.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFH44294.1 - 6.4e-40 136.9 1.5 1.1e-39 136.1 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFH44294.1 - 0.0023 18.5 1.7 0.0045 17.6 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH44294.1 - 0.093 12.0 0.1 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2920 PF11144.8 KFH44294.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Mito_carr PF00153.27 KFH44296.1 - 3.7e-71 235.1 0.5 1.2e-24 86.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFH44296.1 - 1.2e-15 57.7 2.3 1.9e-06 28.2 0.0 3.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFH44296.1 - 2.6e-13 48.7 0.0 2.5e-05 23.8 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFH44296.1 - 1.5e-12 46.1 4.4 3.5e-06 26.2 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KFH44296.1 - 1.5e-11 44.0 0.4 0.18 11.7 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KFH44296.1 - 1.1e-07 31.0 1.9 1.7e-05 24.1 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KFH44296.1 - 0.037 14.4 0.0 23 5.4 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain Cellsynth_D PF03500.13 KFH44296.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Cellulose synthase subunit D Ribonuc_2-5A PF06479.12 KFH44297.1 - 0.21 11.8 0.1 0.5 10.5 0.0 1.6 2 0 0 2 2 2 0 Ribonuclease 2-5A F_bP_aldolase PF01116.20 KFH44298.1 - 1.4e-89 300.3 0.4 1.5e-89 300.2 0.4 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II APH PF01636.23 KFH44299.1 - 3.1e-33 115.7 0.8 5.9e-33 114.8 0.8 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_S24 PF00717.23 KFH44299.1 - 1.6e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Choline_kinase PF01633.20 KFH44299.1 - 0.0069 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1349 PF07081.11 KFH44301.1 - 1.7e-26 93.0 0.1 2.2e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) AhpC-TSA_2 PF13911.6 KFH44302.1 - 3.8e-15 56.0 0.0 9.3e-15 54.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFH44302.1 - 2e-06 27.8 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFH44302.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin Kinesin PF00225.23 KFH44303.1 - 6.3e-57 193.0 0.0 1.3e-56 191.9 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFH44303.1 - 4.1e-12 46.3 0.0 1.8e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Tho2 PF11262.8 KFH44303.1 - 0.21 10.7 0.2 0.36 10.0 0.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Herpes_BLRF2 PF05812.12 KFH44303.1 - 0.66 10.1 4.1 0.37 10.9 0.2 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Jnk-SapK_ap_N PF09744.9 KFH44303.1 - 3.9 7.7 13.3 26 5.0 11.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Abhydrolase_1 PF00561.20 KFH44304.1 - 6.4e-10 39.1 0.0 1.7e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH44304.1 - 1.1e-05 24.8 0.0 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Sortilin-Vps10 PF15902.5 KFH44306.1 - 4.6e-10 38.9 0.0 7.4e-05 21.7 0.0 3.0 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 KFH44306.1 - 3.8e-08 32.9 4.5 4e-05 23.0 0.1 3.5 2 2 1 3 3 3 3 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 KFH44306.1 - 2.8e-06 26.5 24.0 0.21 11.7 0.1 6.6 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_2 PF13088.6 KFH44306.1 - 0.066 12.5 2.7 2.4 7.4 0.0 2.9 2 2 0 2 2 2 0 BNR repeat-like domain DSS1_SEM1 PF05160.13 KFH44307.1 - 4.7e-22 77.8 15.3 6.2e-22 77.4 15.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Nuc_deoxyri_tr2 PF15891.5 KFH44307.1 - 0.49 10.7 3.3 0.8 10.0 3.3 1.5 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Zn_clus PF00172.18 KFH44309.1 - 0.00052 20.1 11.6 0.001 19.2 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KFH44309.1 - 0.01 15.3 0.3 0.039 13.4 0.1 2.1 2 0 0 2 2 2 0 Histone chaperone domain CHZ FAM176 PF14851.6 KFH44310.1 - 0.0019 17.9 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 FAM176 family RTA1 PF04479.13 KFH44310.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 RTA1 like protein PBP1_TM PF14812.6 KFH44310.1 - 0.4 11.1 7.5 0.9 10.0 7.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KFH44310.1 - 1.4 8.2 3.2 2 7.7 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFH44310.1 - 3.3 5.7 3.7 4.3 5.3 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_18 PF00704.28 KFH44311.1 - 8.4e-91 304.9 2.1 9.8e-91 304.7 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5315 PF17242.2 KFH44312.1 - 6e-29 99.7 1.8 6e-29 99.7 1.8 1.7 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) RhlB PF12300.8 KFH44312.1 - 0.018 15.2 5.3 0.018 15.2 5.3 1.8 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB MinE PF03776.14 KFH44312.1 - 0.17 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE SNARE PF05739.19 KFH44313.1 - 3e-09 36.7 3.0 5.6e-09 35.9 3.0 1.5 1 0 0 1 1 1 1 SNARE domain Exonuc_VII_L PF02601.15 KFH44313.1 - 0.0013 18.4 0.3 0.013 15.1 0.0 2.2 1 1 1 2 2 2 1 Exonuclease VII, large subunit Med3 PF11593.8 KFH44313.1 - 0.012 14.8 3.0 0.016 14.4 3.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fusion_gly PF00523.18 KFH44313.1 - 0.037 12.3 0.4 0.054 11.7 0.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Spc7 PF08317.11 KFH44313.1 - 0.039 12.8 2.2 3.1 6.6 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 KFH44313.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein HOOK PF05622.12 KFH44313.1 - 1.3 7.0 5.8 5.7 5.0 0.1 2.0 2 0 0 2 2 2 0 HOOK protein DUF4164 PF13747.6 KFH44313.1 - 1.8 8.9 8.0 4.2 7.7 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 KFH44313.1 - 2.2 8.4 5.0 21 5.2 0.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Trp_syntA PF00290.20 KFH44314.1 - 3e-97 324.5 0.0 5.4e-97 323.7 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KFH44314.1 - 7.7e-50 170.0 1.2 2.2e-49 168.5 1.2 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme STN PF07660.14 KFH44314.1 - 0.12 12.2 0.2 22 4.9 0.1 2.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain SWIM PF04434.17 KFH44315.1 - 0.00013 21.6 0.9 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger Ribosom_S12_S23 PF00164.25 KFH44316.1 - 3.6e-51 171.6 0.6 4.4e-51 171.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ICAP-1_inte_bdg PF10480.9 KFH44317.1 - 3.6 7.5 6.5 8.1 6.4 6.5 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein Ribosomal_L28 PF00830.19 KFH44319.1 - 3.5e-15 55.9 0.6 3.5e-15 55.9 0.6 1.9 2 0 0 2 2 2 1 Ribosomal L28 family Androgen_recep PF02166.16 KFH44319.1 - 0.77 8.5 3.3 1.1 8.1 3.3 1.1 1 0 0 1 1 1 0 Androgen receptor Atg8 PF02991.16 KFH44320.1 - 2.3e-51 172.3 0.2 2.6e-51 172.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFH44320.1 - 3.9e-06 27.2 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 ADK PF00406.22 KFH44321.1 - 4.2e-54 182.7 0.0 6.5e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFH44321.1 - 4.1e-19 69.4 0.1 1e-18 68.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFH44321.1 - 6.9e-18 64.3 0.0 1.8e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFH44321.1 - 2e-06 28.4 0.0 7.5e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH44321.1 - 0.00078 19.6 0.0 0.0039 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFH44321.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KFH44321.1 - 0.19 11.4 0.2 0.52 10.0 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 KFH44321.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF1741 PF08427.10 KFH44322.1 - 6.2e-88 294.4 0.2 1.2e-87 293.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Methyltransf_25 PF13649.6 KFH44323.1 - 1e-12 48.6 0.0 3e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH44323.1 - 2.7e-11 44.0 0.0 9.4e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFH44323.1 - 1.3e-10 41.1 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFH44323.1 - 4.8e-09 36.2 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH44323.1 - 3.5e-07 30.2 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFH44323.1 - 2.3e-06 27.6 0.1 4.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH44323.1 - 1.5e-05 24.6 0.2 3.1e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFH44323.1 - 2e-05 25.3 0.0 5.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFH44323.1 - 0.00026 20.5 0.4 0.00057 19.3 0.4 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 KFH44323.1 - 0.00036 19.9 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFH44323.1 - 0.0005 19.1 0.0 0.00079 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 KFH44323.1 - 0.00068 19.5 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 KFH44323.1 - 0.0017 18.2 0.1 0.0028 17.4 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KFH44323.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KFH44323.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KFH44323.1 - 0.015 14.6 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KFH44323.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KFH44323.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFH44323.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 KFH44323.1 - 0.13 13.2 0.0 0.36 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 KFH44323.1 - 0.18 11.3 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase AbfB PF05270.13 KFH44324.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain Adipogenin PF15202.6 KFH44326.1 - 1.6 8.8 5.3 2.2 8.3 5.3 1.2 1 0 0 1 1 1 0 Adipogenin UbiA PF01040.18 KFH44327.1 - 5.3e-41 140.6 17.0 6.8e-41 140.2 17.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MFS_1 PF07690.16 KFH44328.1 - 4.2e-22 78.5 40.6 3.5e-19 68.9 28.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH44328.1 - 3e-15 56.0 21.5 6.5e-15 54.9 21.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 KFH44328.1 - 0.042 13.8 0.6 0.075 13.0 0.6 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF4131 PF13567.6 KFH44328.1 - 0.38 10.4 0.0 0.38 10.4 0.0 2.9 2 2 1 4 4 4 0 Domain of unknown function (DUF4131) DUF2183 PF09949.9 KFH44329.1 - 1.2e-31 109.0 0.0 2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1992 PF09350.10 KFH44330.1 - 1.4e-20 73.2 0.3 3.4e-20 72.0 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Aminotran_3 PF00202.21 KFH44331.1 - 2e-92 309.9 0.0 2.5e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III XRN_M PF17846.1 KFH44332.1 - 1.6e-142 475.6 1.7 2.3e-142 475.0 0.0 2.0 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KFH44332.1 - 7.5e-99 330.1 0.0 1.3e-98 329.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KFH44332.1 - 0.056 13.5 3.4 0.11 12.7 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFH44332.1 - 0.25 11.2 3.4 0.57 10.1 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4834 PF16118.5 KFH44334.1 - 0.053 14.5 0.0 0.092 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Caudo_bapla16 PF16792.5 KFH44334.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Herpes_U47 PF05467.11 KFH44334.1 - 0.56 8.3 2.2 0.8 7.8 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Aminotran_1_2 PF00155.21 KFH44336.1 - 4.3e-88 295.9 0.0 5.3e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ANAPC4_WD40 PF12894.7 KFH44337.1 - 1.8e-05 25.0 0.0 0.099 13.0 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFH44337.1 - 0.00035 21.3 4.2 0.058 14.3 0.1 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Mo25 PF08569.11 KFH44338.1 - 5e-128 427.1 0.0 5.6e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Sec7_N PF12783.7 KFH44338.1 - 0.071 13.0 1.1 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Sugar_tr PF00083.24 KFH44339.1 - 1.6e-81 274.5 18.6 1.9e-81 274.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH44339.1 - 1.1e-18 67.3 29.8 2.9e-15 56.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 KFH44339.1 - 2.4 7.2 25.7 0.013 14.6 10.0 2.4 2 1 0 2 2 2 0 Acyltransferase family SWIB PF02201.18 KFH44340.1 - 5.3e-21 74.3 0.0 1.2e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 SWIB/MDM2 domain CYTH PF01928.21 KFH44340.1 - 0.079 12.9 0.1 3.7 7.5 0.0 2.7 1 1 2 3 3 3 0 CYTH domain SDA1 PF05285.12 KFH44341.1 - 0.004 16.6 18.9 0.004 16.6 18.9 2.2 2 0 0 2 2 2 1 SDA1 FUSC_2 PF13515.6 KFH44341.1 - 0.39 10.9 1.8 0.65 10.1 0.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like His_Phos_2 PF00328.22 KFH44342.1 - 0.00038 19.9 0.0 0.0077 15.6 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Calc_CGRP_IAPP PF00214.19 KFH44342.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family TipAS PF07739.13 KFH44342.1 - 0.17 12.4 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain tRNA-synt_1 PF00133.22 KFH44343.1 - 6.9e-226 751.2 0.0 1.5e-225 750.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFH44343.1 - 4.7e-25 88.3 0.0 1.5e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFH44343.1 - 3e-15 55.9 0.0 7.6e-06 24.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFH44343.1 - 0.0068 15.8 0.0 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 KFH44344.1 - 6.8e-66 222.3 0.0 8.9e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44344.1 - 2.5e-31 108.9 0.0 3e-29 102.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH44344.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH44344.1 - 0.0074 16.2 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH44344.1 - 0.0074 15.6 0.1 0.58 9.4 0.0 2.6 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 KFH44344.1 - 0.011 15.4 0.1 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFH44344.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Baculo_PEP_C PF04513.12 KFH44345.1 - 0.023 14.7 0.1 0.66 10.0 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 KFH44345.1 - 0.032 14.0 3.8 4.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Bacterial collagen, middle region ApoLp-III PF07464.11 KFH44345.1 - 0.034 14.2 0.2 21 5.2 0.0 3.3 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Gly_transf_sug PF04488.15 KFH44345.1 - 0.069 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Coprogen_oxidas PF01218.18 KFH44346.1 - 4.9e-145 481.8 0.1 5.8e-145 481.6 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase OPT PF03169.15 KFH44347.1 - 5.5e-144 481.1 27.3 6.2e-144 481.0 27.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MscL PF01741.18 KFH44347.1 - 0.056 13.7 0.7 16 5.8 0.2 3.6 3 1 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Sfi1 PF08457.10 KFH44348.1 - 5.8e-21 74.7 42.3 6.2e-19 68.0 27.7 3.1 3 0 0 3 3 3 3 Sfi1 spindle body protein MitMem_reg PF13012.6 KFH44349.1 - 6.5e-37 126.4 0.0 1.4e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFH44349.1 - 1.9e-31 108.5 0.0 4.2e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KFH44349.1 - 0.0084 15.8 6.4 0.012 15.3 6.4 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain Connexin PF00029.19 KFH44349.1 - 0.58 9.9 2.9 0.85 9.3 2.9 1.2 1 0 0 1 1 1 0 Connexin AA_permease PF00324.21 KFH44350.1 - 2.5e-140 468.2 41.9 2.9e-140 468.0 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH44350.1 - 1.6e-36 126.1 45.8 2.2e-36 125.6 45.8 1.2 1 0 0 1 1 1 1 Amino acid permease Rav1p_C PF12234.8 KFH44351.1 - 3.6e-265 881.4 0.4 2.1e-139 465.9 0.0 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal HOOK PF05622.12 KFH44352.1 - 2.3e-11 42.6 51.0 2.3e-11 42.6 51.0 3.2 3 0 0 3 3 3 2 HOOK protein Alliinase_C PF04864.13 KFH44352.1 - 0.027 13.4 0.1 0.051 12.4 0.1 1.4 1 0 0 1 1 1 0 Allinase FeoC PF09012.10 KFH44352.1 - 0.098 12.7 0.5 0.38 10.8 0.3 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator S36_mt PF10937.8 KFH44353.1 - 1.4e-41 142.6 1.3 1.8e-41 142.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial RasGAP PF00616.19 KFH44354.1 - 8.3e-35 120.4 0.3 1.1e-31 110.2 0.3 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase BRCA-2_helical PF09169.10 KFH44355.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2, helical JmjC PF02373.22 KFH44356.1 - 2.4e-09 37.6 0.0 6.7e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KFH44356.1 - 5.6e-08 32.9 12.0 5.6e-08 32.9 12.0 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KFH44356.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Fungal_trans PF04082.18 KFH44357.1 - 7.4e-12 44.9 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44357.1 - 0.00017 21.7 9.8 0.00028 20.9 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uso1_p115_head PF04869.14 KFH44358.1 - 1.6e-113 379.0 0.0 3.2e-113 378.0 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KFH44358.1 - 5.1e-21 75.3 35.1 5.1e-21 75.3 35.1 3.7 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 KFH44358.1 - 0.27 10.8 54.9 0.2 11.2 45.2 3.3 1 1 1 2 2 2 0 Intermediate filament protein FAM76 PF16046.5 KFH44358.1 - 0.51 9.6 44.8 2.2 7.6 10.7 3.4 1 1 1 3 3 3 0 FAM76 protein Baculo_PEP_C PF04513.12 KFH44358.1 - 4.2 7.4 20.9 0.33 11.0 4.8 4.4 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_TACC PF12709.7 KFH44358.1 - 4.9 7.7 28.6 0.17 12.4 2.8 5.0 2 1 3 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins PPTA PF01239.22 KFH44360.1 - 9e-42 139.6 14.9 1.2e-09 37.6 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 KFH44360.1 - 0.15 11.8 0.1 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) ketoacyl-synt PF00109.26 KFH44362.1 - 2e-68 230.7 0.0 7.2e-68 228.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFH44362.1 - 1.9e-33 115.0 0.0 3.8e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KFH44362.1 - 1.1e-32 111.8 0.1 3.7e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KFH44362.1 - 9.7e-30 104.2 0.0 3e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 KFH44362.1 - 9.2e-23 80.7 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 KFH44362.1 - 1.3e-15 57.8 8.2 1e-11 45.1 0.6 4.4 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KFH44362.1 - 3.5e-15 56.6 0.0 1.3e-14 54.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH44362.1 - 1.4e-10 41.3 0.0 4.1e-10 39.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH44362.1 - 7.3e-10 39.4 0.0 4.9e-09 36.8 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH44362.1 - 6.8e-09 36.3 0.0 1.3e-07 32.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KFH44362.1 - 7.7e-09 35.8 1.0 2.2e-08 34.3 1.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KFH44362.1 - 2e-06 27.4 0.0 4.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KFH44362.1 - 4.6e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KFH44362.1 - 1e-05 25.4 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KFH44362.1 - 0.0018 17.7 0.3 0.012 15.0 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFH44362.1 - 0.0042 16.9 0.3 0.014 15.2 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.6 KFH44362.1 - 0.0054 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFH44362.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KFH44362.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 4HBT PF03061.22 KFH44363.1 - 8.3e-06 26.1 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Abhydrolase_3 PF07859.13 KFH44364.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pox_RNA_pol PF03293.14 KFH44364.1 - 0.059 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Pyr_redox_2 PF07992.14 KFH44365.1 - 1.6e-45 155.6 3.6 2.2e-45 155.1 3.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH44365.1 - 2.8e-10 40.6 7.3 1.1e-09 38.7 2.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFH44365.1 - 1e-09 38.2 0.0 1.7e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 KFH44365.1 - 4.3e-07 30.4 0.1 1.5e-06 28.6 0.1 2.0 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KFH44365.1 - 0.0041 16.3 0.1 0.91 8.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFH44365.1 - 0.0063 16.5 0.3 3.2 7.7 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding DUF2767 PF10965.8 KFH44365.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) NAD_binding_7 PF13241.6 KFH44365.1 - 0.61 10.6 2.7 4.3 7.8 0.1 2.5 1 1 1 2 2 2 0 Putative NAD(P)-binding Hydrolase_6 PF13344.6 KFH44366.1 - 4e-15 55.8 0.0 6.6e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH44366.1 - 0.00036 20.5 0.0 0.0018 18.3 0.0 2.1 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFH44366.1 - 0.0024 18.2 0.3 0.22 11.8 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFH44366.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFH44366.1 - 0.02 15.0 0.1 0.085 12.9 0.1 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ig_GlcNase PF18368.1 KFH44367.1 - 1.7e-35 121.3 0.3 9.9e-35 118.9 0.1 2.3 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KFH44367.1 - 8.8e-11 42.5 0.0 2.9e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFH44367.1 - 1.2e-05 24.9 0.3 0.00015 21.4 0.0 2.6 3 0 0 3 3 3 1 Ig-fold domain Mannosidase_ig PF17786.1 KFH44367.1 - 0.0003 21.3 0.4 0.0016 19.0 0.1 2.4 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 KFH44367.1 - 0.15 11.1 0.1 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain AATase PF07247.12 KFH44368.1 - 3.8e-08 32.3 0.0 6.4e-07 28.3 0.0 2.0 2 0 0 2 2 2 2 Alcohol acetyltransferase Acyl_transf_3 PF01757.22 KFH44369.1 - 1.1e-19 70.7 20.8 1.1e-19 70.7 20.8 1.5 1 1 1 2 2 2 1 Acyltransferase family MIG-14_Wnt-bd PF06664.12 KFH44369.1 - 0.025 13.8 2.6 0.31 10.2 1.9 2.5 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Trep_Strep PF09605.10 KFH44369.1 - 0.25 11.3 3.8 0.33 10.9 1.7 2.3 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Glyco_hydro_1 PF00232.18 KFH44371.1 - 4.4e-73 246.2 0.7 5.9e-71 239.2 0.7 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Fib_alpha PF08702.10 KFH44372.1 - 0.0094 16.1 13.6 0.014 15.6 1.9 3.4 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family Sec3_C PF09763.9 KFH44372.1 - 0.066 11.6 13.8 0.11 10.8 13.8 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 PKcGMP_CC PF16808.5 KFH44372.1 - 0.21 11.5 0.1 0.21 11.5 0.1 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 KFH44372.1 - 3.7 7.7 7.0 34 4.5 6.7 2.3 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component MAD PF05557.13 KFH44372.1 - 7.7 4.7 34.6 5.2 5.3 22.7 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DivIVA PF05103.13 KFH44372.1 - 9.6 6.3 32.4 2.4 8.3 0.1 3.8 3 1 0 3 3 3 0 DivIVA protein DEAD PF00270.29 KFH44373.1 - 2.4e-50 170.8 0.0 5.6e-50 169.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH44373.1 - 1.9e-33 115.1 0.0 1.9e-30 105.5 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KFH44373.1 - 0.0019 17.0 0.2 0.0069 15.2 0.0 2.0 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 adh_short PF00106.25 KFH44374.1 - 1.7e-12 47.2 0.0 2.1e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH44374.1 - 1.8e-09 37.5 0.0 2.2e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFH44374.1 - 0.00019 21.4 0.3 0.00023 21.1 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFH44374.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 KR domain Hydantoinase_B PF02538.14 KFH44374.1 - 0.095 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF1776 PF08643.10 KFH44374.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.23 KFH44377.1 - 2.3e-20 72.7 2.7 6e-20 71.4 2.7 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH44377.1 - 2.2e-10 40.5 0.4 5e-10 39.3 0.1 1.7 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 KFH44377.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PseudoU_synth_2 PF00849.22 KFH44378.1 - 8.5e-30 104.0 0.0 1.2e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KFH44378.1 - 0.042 13.6 0.2 0.099 12.4 0.2 1.6 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.6 KFH44378.1 - 0.067 13.0 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 KFH44378.1 - 0.093 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATP-grasp_2 PF08442.10 KFH44379.1 - 1.1e-44 152.4 0.1 6.9e-43 146.6 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFH44379.1 - 9.1e-16 58.0 1.6 9.1e-16 58.0 1.6 2.1 2 2 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KFH44379.1 - 0.039 13.4 0.1 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 ATP-grasp domain FAD_binding_4 PF01565.23 KFH44380.1 - 3.1e-33 114.4 4.6 7.2e-33 113.3 4.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH44380.1 - 1.5e-08 34.6 0.1 2.5e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Melibiase PF02065.18 KFH44382.1 - 2.2e-150 500.4 0.0 2.7e-150 500.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KFH44382.1 - 1.1e-79 267.6 0.0 1.9e-79 266.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KFH44382.1 - 7.6e-19 68.0 0.0 1.7e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KFH44382.1 - 0.033 13.3 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 GFO_IDH_MocA PF01408.22 KFH44383.1 - 1.1e-15 58.5 0.0 2.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 KFH44384.1 - 2.2e-38 131.7 1.4 2.8e-38 131.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH44384.1 - 3.7e-29 102.0 1.3 5.2e-29 101.5 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH44384.1 - 9.1e-09 35.5 2.3 2.6e-08 34.0 2.3 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KFH44384.1 - 0.00021 20.4 0.5 0.0003 19.9 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH44384.1 - 0.0064 16.0 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KFH44384.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KFH44385.1 - 7.6e-39 133.6 43.1 7.6e-39 133.6 43.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.6 KFH44386.1 - 6.5e-18 65.5 0.0 9.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFH44386.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_88 PF07470.13 KFH44387.1 - 1.9e-76 257.4 2.6 2.3e-76 257.1 2.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KFH44387.1 - 0.25 10.8 6.7 0.56 9.7 0.2 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Fungal_trans_2 PF11951.8 KFH44388.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KFH44389.1 - 1.1e-06 27.8 0.1 1.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain FSH1 PF03959.13 KFH44390.1 - 2.7e-27 95.8 0.0 3.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFH44390.1 - 0.048 13.5 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase RGS PF00615.19 KFH44391.1 - 7.7e-07 29.4 0.0 8.2e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain FAD_binding_3 PF01494.19 KFH44392.1 - 3.9e-16 59.2 8.8 5.8e-11 42.2 0.2 3.2 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH44392.1 - 2.7e-05 24.3 0.6 7.8e-05 22.8 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH44392.1 - 0.002 17.8 2.5 0.005 16.5 2.5 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KFH44392.1 - 0.021 13.9 0.0 0.085 11.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KFH44392.1 - 0.03 13.6 1.9 2.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFH44392.1 - 0.03 14.3 1.1 0.072 13.1 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFH44392.1 - 0.03 13.5 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH44392.1 - 0.056 14.0 0.2 0.056 14.0 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mac PF12464.8 KFH44393.1 - 9.8e-15 54.5 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KFH44393.1 - 1.7e-13 50.1 6.3 4.2e-12 45.6 2.9 3.2 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KFH44393.1 - 7.1e-13 47.7 11.4 3.2e-12 45.7 3.6 3.5 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Fungal_trans PF04082.18 KFH44394.1 - 1.5e-14 53.6 0.1 2.7e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2706 PF10913.8 KFH44394.1 - 0.092 12.6 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Pyr_redox_3 PF13738.6 KFH44395.1 - 1.6e-10 40.7 0.0 2.9e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFH44395.1 - 2.4e-09 36.2 0.0 1.2e-08 33.9 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH44395.1 - 2.7e-09 37.1 0.0 2.3e-07 31.0 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH44395.1 - 5.7e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH44395.1 - 3.7e-07 30.1 0.0 1.7e-05 24.6 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFH44395.1 - 1.8e-06 27.3 0.0 7.3e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFH44395.1 - 3.8e-06 26.3 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KFH44395.1 - 3.3e-05 24.4 0.0 0.36 11.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFH44395.1 - 0.0035 16.7 0.0 0.0086 15.4 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFH44395.1 - 0.0061 15.9 0.0 0.11 11.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KFH44395.1 - 0.018 14.1 0.0 0.84 8.6 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.15 KFH44395.1 - 0.019 13.5 0.0 1.2 7.7 0.0 2.4 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.20 KFH44395.1 - 0.02 14.9 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KFH44395.1 - 0.027 14.5 0.1 0.79 9.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFH44395.1 - 0.081 12.3 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ketoacyl-synt PF00109.26 KFH44396.1 - 2.5e-66 223.8 1.0 6e-66 222.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFH44396.1 - 2.2e-58 197.8 0.2 4e-58 197.0 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFH44396.1 - 1.8e-56 190.9 0.2 4.8e-56 189.5 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFH44396.1 - 7.2e-42 144.0 0.5 1.4e-41 143.0 0.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH44396.1 - 6.5e-38 129.4 0.1 3.8e-37 126.9 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH44396.1 - 3.4e-15 57.3 0.3 1.8e-14 54.9 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH44396.1 - 7.9e-14 51.7 0.0 7e-12 45.5 0.0 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH44396.1 - 3.9e-12 46.8 0.0 2.1e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KFH44396.1 - 7.3e-11 41.9 0.0 2.2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KFH44396.1 - 1.4e-10 41.6 0.8 8.7e-10 39.0 0.3 2.6 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KFH44396.1 - 6.5e-08 32.6 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH44396.1 - 3.2e-06 27.7 0.0 0.00015 22.3 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 KFH44396.1 - 1.6e-05 24.4 0.1 3.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 KFH44396.1 - 2.5e-05 24.9 0.0 0.00012 22.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH44396.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFH44396.1 - 0.00018 21.8 0.7 0.00053 20.3 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KFH44396.1 - 0.14 11.9 0.0 0.72 9.6 0.0 2.2 2 1 0 2 2 2 0 Lysine methyltransferase CoA_binding PF02629.19 KFH44397.1 - 4.6e-23 81.7 1.0 4.6e-23 81.7 1.0 2.0 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFH44397.1 - 3.1e-18 66.1 1.6 6.8e-18 64.9 1.6 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFH44397.1 - 2.7e-09 37.0 0.2 6e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Fungal_trans PF04082.18 KFH44399.1 - 2.3e-18 66.2 0.0 3.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44399.1 - 5.7e-08 32.7 8.2 1.1e-07 31.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOGA PF11365.8 KFH44399.1 - 0.0054 17.8 0.7 0.17 13.0 0.7 2.3 2 0 0 2 2 2 1 Protein SOGA TolA_bind_tri PF16331.5 KFH44399.1 - 0.086 12.9 1.5 0.18 11.9 1.5 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF2304 PF10066.9 KFH44400.1 - 0.26 11.5 10.6 0.059 13.6 1.9 3.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF2909 PF11137.8 KFH44400.1 - 1.2 9.1 6.4 0.61 10.1 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) Fungal_trans PF04082.18 KFH44401.1 - 1.8e-12 46.9 0.0 3.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44401.1 - 1.5e-08 34.6 10.0 2.6e-08 33.8 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 KFH44402.1 - 6.3e-14 52.1 0.6 3.2e-13 49.8 0.6 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFH44402.1 - 0.0012 18.5 0.5 0.0021 17.7 0.5 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFH44402.1 - 0.048 12.3 0.0 0.068 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Acetyltransf_10 PF13673.7 KFH44403.1 - 7.1e-09 35.7 0.0 9.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH44403.1 - 1.1e-07 32.1 0.1 1.3e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH44403.1 - 0.00024 21.5 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KFH44404.1 - 8.7e-10 38.8 0.3 1.5e-09 38.0 0.3 1.3 1 1 0 1 1 1 1 NUDIX domain Rft-1 PF04506.13 KFH44405.1 - 1.5e-145 485.8 8.3 1.7e-145 485.6 8.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KFH44405.1 - 1.4e-10 41.0 5.1 1.4e-10 41.0 5.1 2.6 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KFH44405.1 - 0.00047 19.5 6.9 0.0031 16.8 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Pro_CA PF00484.19 KFH44406.1 - 7.9e-12 45.7 0.2 1.9e-10 41.3 0.1 2.0 2 0 0 2 2 2 2 Carbonic anhydrase MFS_1 PF07690.16 KFH44407.1 - 3.7e-28 98.5 58.3 1.3e-21 76.9 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ldr_toxin PF13940.6 KFH44407.1 - 0.39 10.8 2.8 0.96 9.6 0.7 2.6 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system DUF3591 PF12157.8 KFH44409.1 - 3.6e-175 582.9 0.6 3.6e-175 582.9 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KFH44409.1 - 0.0051 16.8 0.7 0.0099 15.9 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KFH44409.1 - 0.0067 16.2 0.5 0.019 14.8 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF3844 PF12955.7 KFH44410.1 - 4.7e-36 123.1 3.3 8.5e-36 122.3 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KFH44410.1 - 0.16 12.4 7.8 0.83 10.1 7.8 2.2 1 1 0 1 1 1 0 EGF-like domain ANTH PF07651.16 KFH44411.1 - 1e-66 224.8 0.6 3.5e-66 223.0 0.2 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 KFH44411.1 - 6.1e-07 29.5 0.0 2.1e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 ENTH domain Mito_carr PF00153.27 KFH44412.1 - 1.8e-43 146.4 0.2 1.2e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein F-box-like PF12937.7 KFH44413.1 - 1.1e-10 41.3 0.2 2.4e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH44413.1 - 0.00087 19.1 0.8 0.0019 18.0 0.8 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KFH44413.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SelP_N PF04592.14 KFH44413.1 - 6.7 6.0 17.5 12 5.2 17.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CS PF04969.16 KFH44414.1 - 1.3e-15 58.1 0.4 2.4e-15 57.3 0.1 1.6 2 0 0 2 2 2 1 CS domain Rhodanese PF00581.20 KFH44415.1 - 2.3e-31 108.5 0.0 2.2e-07 31.4 0.0 4.5 4 1 0 4 4 4 4 Rhodanese-like domain FMO-like PF00743.19 KFH44416.1 - 1.6e-12 46.6 0.0 3.4e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFH44416.1 - 1.4e-09 37.6 0.0 5.2e-09 35.8 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH44416.1 - 2.7e-09 37.1 0.2 0.0032 17.1 0.0 4.0 2 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH44416.1 - 5.3e-09 36.2 0.0 2.6e-07 30.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH44416.1 - 7.5e-08 31.9 0.0 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH44416.1 - 9.5e-08 31.6 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFH44416.1 - 1.6e-05 24.3 0.0 0.0046 16.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFH44416.1 - 0.00094 18.5 0.0 0.0042 16.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KFH44416.1 - 0.0087 16.6 0.1 1.9 9.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFH44416.1 - 0.031 14.3 0.0 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFH44416.1 - 0.042 12.9 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KFH44416.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.15 KFH44416.1 - 0.061 11.9 0.2 3.5 6.1 0.0 2.6 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KFH44416.1 - 0.068 13.2 1.3 7.9 6.4 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFH44416.1 - 0.084 11.9 0.0 3.5 6.6 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KFH44416.1 - 0.2 10.3 0.0 2.5 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3_C PF01915.22 KFH44417.1 - 2.6e-41 141.9 0.0 6.1e-41 140.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH44417.1 - 3e-26 92.5 0.0 8.4e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFH44417.1 - 5.6e-26 90.4 0.3 1.1e-25 89.5 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Utp11 PF03998.13 KFH44418.1 - 7.4e-62 209.5 17.9 8.4e-62 209.3 17.9 1.0 1 0 0 1 1 1 1 Utp11 protein Hap4_Hap_bind PF10297.9 KFH44418.1 - 0.25 11.5 3.7 0.57 10.4 3.7 1.6 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 SLATT_5 PF18160.1 KFH44418.1 - 0.54 9.6 3.9 0.35 10.2 0.5 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 FlxA PF14282.6 KFH44418.1 - 1.3 9.0 6.4 0.66 10.0 0.1 2.8 3 0 0 3 3 3 0 FlxA-like protein FRG1 PF06229.12 KFH44419.1 - 1.5e-51 174.9 0.0 2e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KFH44419.1 - 0.0014 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Fascin domain DNA_meth_N PF18284.1 KFH44419.1 - 0.19 11.7 0.8 0.41 10.6 0.8 1.5 1 0 0 1 1 1 0 DNA methylase N-terminal domain SVIP PF15811.5 KFH44419.1 - 5 7.6 13.3 0.4 11.2 6.0 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein GNVR PF13807.6 KFH44420.1 - 0.0037 17.2 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase DUF948 PF06103.11 KFH44421.1 - 0.032 14.5 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DHHC PF01529.20 KFH44421.1 - 0.037 14.1 7.1 0.61 10.2 0.6 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2878 PF11086.8 KFH44421.1 - 3.5 7.8 21.2 0.55 10.4 10.9 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2878) Cmc1 PF08583.10 KFH44422.1 - 1.1e-15 57.4 2.2 1.1e-15 57.4 2.2 1.8 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KFH44422.1 - 0.032 14.4 0.7 9 6.6 0.1 2.4 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 KFH44422.1 - 0.054 13.5 0.2 0.13 12.3 0.2 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 KFH44422.1 - 0.61 10.5 6.7 12 6.4 6.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) ADH_N PF08240.12 KFH44423.1 - 4.4e-30 103.8 1.5 5e-30 103.6 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH44423.1 - 2e-24 86.0 0.4 3.5e-24 85.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH44423.1 - 9.6e-11 41.6 1.4 1.5e-10 40.9 1.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFH44423.1 - 6.2e-08 33.8 0.3 1.9e-07 32.2 0.1 1.9 2 1 0 2 2 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KFH44423.1 - 0.001 18.4 0.3 0.0024 17.1 0.3 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFH44423.1 - 0.0012 18.1 1.9 0.0021 17.4 1.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFH44423.1 - 0.01 16.3 0.1 0.27 11.8 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFH44423.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KFH44423.1 - 0.016 14.0 0.4 0.026 13.3 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein PALP PF00291.25 KFH44423.1 - 0.032 13.7 2.6 0.066 12.6 2.6 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_25 PF13649.6 KFH44423.1 - 0.043 14.5 0.1 0.086 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.23 KFH44424.1 - 2.6e-92 308.9 0.1 3.5e-92 308.4 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH44424.1 - 5.6e-46 155.2 0.5 5.9e-45 151.9 0.3 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFH44424.1 - 2.3e-06 27.4 2.3 0.00011 21.9 1.3 2.7 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF5505 PF17610.2 KFH44424.1 - 0.069 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5505) ACP_syn_III PF08545.10 KFH44424.1 - 0.18 11.7 1.5 19 5.2 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LSM PF01423.22 KFH44425.1 - 1.1e-21 76.3 0.5 1.2e-21 76.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain Pex2_Pex12 PF04757.14 KFH44426.1 - 3.3e-36 125.0 1.2 4.5e-36 124.6 1.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KFH44426.1 - 0.00039 20.5 4.0 0.00083 19.5 4.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFH44426.1 - 0.011 15.8 2.0 0.035 14.1 2.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFH44426.1 - 0.013 15.4 1.2 0.029 14.3 1.2 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH44426.1 - 0.18 11.7 5.5 0.13 12.1 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH44426.1 - 0.67 9.9 9.5 2.3 8.2 5.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sulfotransfer_4 PF17784.1 KFH44427.1 - 1.8e-60 204.5 0.0 2e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH44427.1 - 0.0018 18.7 1.4 0.15 12.4 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sugar_tr PF00083.24 KFH44428.1 - 2.4e-125 419.0 20.6 2.8e-125 418.7 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH44428.1 - 5.7e-22 78.1 31.6 4.1e-15 55.6 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KFH44428.1 - 0.031 13.6 3.1 0.47 9.7 0.2 2.6 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Zip PF02535.22 KFH44429.1 - 4e-55 187.4 1.0 9.9e-55 186.1 1.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.22 KFH44429.1 - 2.1 8.4 7.7 0.31 11.1 0.2 2.8 3 1 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.18 KFH44431.1 - 9.6e-10 37.9 0.0 1.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44431.1 - 1.9e-06 27.9 9.9 1.9e-06 27.9 9.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_path_suppress PF15991.5 KFH44431.1 - 5.5 7.0 14.0 8.1 6.5 5.2 2.6 2 1 0 2 2 2 0 G-protein pathway suppressor AtuA PF07287.11 KFH44432.1 - 4.5e-110 367.7 0.0 5.3e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA IQ PF00612.27 KFH44433.1 - 0.00026 20.5 0.2 0.00073 19.1 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Aldolase_II PF00596.21 KFH44434.1 - 6.4e-42 143.6 2.1 8.6e-42 143.2 2.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M1_N PF17900.1 KFH44435.1 - 2.2e-05 24.7 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KFH44435.1 - 0.0014 18.3 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KFH44435.1 - 0.043 14.2 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats AtuA PF07287.11 KFH44436.1 - 0.029 13.1 0.1 0.033 12.9 0.1 1.0 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA D-ser_dehydrat PF14031.6 KFH44437.1 - 1.3e-20 73.8 0.0 5.2e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KFH44437.1 - 4.4e-10 39.6 0.0 9.4e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain PQ-loop PF04193.14 KFH44438.1 - 4.9e-27 93.5 1.5 5.5e-18 64.5 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.13 KFH44438.1 - 0.053 12.8 2.5 0.076 12.3 2.5 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA OTT_1508_deam PF14441.6 KFH44439.1 - 4.6e-19 68.2 0.1 8.8e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase SRF-TF PF00319.18 KFH44440.1 - 1.2e-22 79.2 0.3 1.7e-22 78.6 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAD_binding_2 PF00890.24 KFH44441.1 - 1.8e-85 287.6 0.9 2.2e-85 287.2 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KFH44441.1 - 1.5e-22 79.5 0.1 9.2e-21 73.8 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KFH44441.1 - 5.4e-15 55.8 0.4 9.5e-15 55.0 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH44441.1 - 4.7e-10 39.4 0.9 2.4e-09 37.0 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH44441.1 - 6.1e-09 36.0 2.6 3.9e-07 30.2 0.6 3.2 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH44441.1 - 2.7e-07 30.1 0.2 2.7e-06 26.8 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH44441.1 - 2.2e-06 27.2 0.0 0.048 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH44441.1 - 4.3e-06 25.7 1.6 0.0084 14.9 0.4 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 KFH44441.1 - 6.4e-05 22.4 1.0 0.00013 21.3 1.0 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFH44441.1 - 0.00088 18.6 2.0 0.084 12.1 0.7 2.4 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 KFH44441.1 - 0.002 17.5 0.6 0.081 12.2 0.1 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KFH44441.1 - 0.002 17.3 2.7 0.2 10.7 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KFH44441.1 - 0.0026 18.3 2.3 0.22 12.1 0.4 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFH44441.1 - 0.029 13.7 0.7 0.053 12.8 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MAT1 PF06391.13 KFH44442.1 - 3.6e-34 118.4 5.2 5.1e-34 117.9 5.2 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KFH44442.1 - 1.6e-31 108.0 9.5 2.7e-31 107.2 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH44442.1 - 7.6e-06 25.7 5.8 1.5e-05 24.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH44442.1 - 0.00014 21.6 6.3 0.0004 20.2 6.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 KFH44442.1 - 0.0015 18.4 10.5 0.0025 17.8 10.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.6 KFH44442.1 - 0.0023 18.2 7.6 0.004 17.4 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain DUF1682 PF07946.14 KFH44442.1 - 0.01 15.0 5.8 0.015 14.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3797 PF12677.7 KFH44442.1 - 0.023 14.6 2.6 0.053 13.4 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-C3HC4_2 PF13923.6 KFH44442.1 - 0.034 14.0 9.1 0.16 11.8 9.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFH44442.1 - 0.08 12.8 12.4 1.9 8.3 12.9 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFH44442.1 - 0.27 11.4 3.4 0.64 10.2 3.4 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFH44442.1 - 0.29 11.2 6.6 0.62 10.1 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFH44442.1 - 0.67 10.0 11.3 6.6 6.8 11.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain CorA PF01544.18 KFH44442.1 - 0.82 8.9 2.9 1.1 8.5 2.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-UDP PF14569.6 KFH44442.1 - 1.1 9.4 8.7 5.4 7.2 8.7 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KFH44442.1 - 3.5 7.6 7.9 8.4 6.4 2.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 GAGE PF05831.11 KFH44443.1 - 5.7 7.5 8.4 9 6.9 8.4 1.2 1 0 0 1 1 1 0 GAGE protein tRNA-synt_2 PF00152.20 KFH44447.1 - 2.4e-76 256.8 0.0 3.2e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KFH44447.1 - 0.1 12.1 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KFH44447.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) TPR_1 PF00515.28 KFH44448.1 - 6.7e-39 130.2 18.3 4e-06 26.4 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KFH44448.1 - 3.1e-36 123.1 13.3 1.2e-18 66.8 1.4 3.6 3 1 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 KFH44448.1 - 1.9e-35 118.1 15.3 0.00018 21.4 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KFH44448.1 - 3.4e-14 52.2 27.8 0.0065 16.1 1.0 8.1 8 2 0 8 8 8 4 TPR repeat TPR_8 PF13181.6 KFH44448.1 - 2.4e-13 49.1 29.8 0.00043 20.3 0.1 9.1 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFH44448.1 - 3.5e-13 49.6 10.9 4.1e-10 39.8 0.2 5.4 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFH44448.1 - 3.9e-13 49.0 8.6 0.19 12.7 0.0 8.6 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFH44448.1 - 5.2e-13 48.0 5.2 0.00095 19.0 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH44448.1 - 3.9e-12 46.5 11.8 0.012 16.1 0.0 7.2 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFH44448.1 - 1.1e-11 44.3 6.1 1.5 9.3 0.2 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH44448.1 - 1.8e-11 44.5 17.1 9.8e-05 22.9 0.2 6.2 5 2 3 8 8 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFH44448.1 - 8.2e-11 41.9 0.3 0.0011 19.1 0.0 4.7 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFH44448.1 - 6.8e-08 32.1 2.5 0.031 14.1 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH44448.1 - 0.00035 20.7 1.4 0.093 13.0 0.3 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFH44448.1 - 0.0005 20.5 12.4 11 6.9 0.0 7.5 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF5486 PF17588.2 KFH44448.1 - 0.044 13.7 3.4 0.48 10.3 1.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5486) GerD PF17898.1 KFH44448.1 - 1.3 9.0 13.9 0.38 10.7 2.4 3.5 4 0 0 4 4 3 0 Spore germination GerD central core domain DUF5113 PF17140.4 KFH44448.1 - 2.9 7.7 6.1 88 2.9 0.2 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF5113) LIN37 PF15306.6 KFH44448.1 - 5.4 7.2 9.2 0.61 10.3 3.7 2.2 2 0 0 2 2 2 0 LIN37 DUF3391 PF11871.8 KFH44448.1 - 8.2 7.0 8.7 1.1 9.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) TPR_3 PF07720.12 KFH44448.1 - 9.8 6.3 6.9 8.6 6.5 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1098 PF06497.11 KFH44449.1 - 0.15 12.5 1.1 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Rhodanese PF00581.20 KFH44452.1 - 1.7e-07 31.7 0.0 3e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Mito_carr PF00153.27 KFH44453.1 - 1.7e-64 213.8 2.0 3.8e-21 74.8 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF4148 PF13663.6 KFH44453.1 - 0.7 10.1 0.0 0.7 10.1 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4148) MBOAT PF03062.19 KFH44454.1 - 7.1e-47 160.4 16.5 1.5e-46 159.4 16.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FUSC PF04632.12 KFH44456.1 - 0.044 12.3 1.0 0.06 11.9 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family 2OG-FeII_Oxy PF03171.20 KFH44457.1 - 0.0016 18.9 0.0 0.009 16.5 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.27 KFH44458.1 - 1.7e-44 151.7 0.0 2.7e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFH44458.1 - 6.2e-36 123.7 6.7 1.6e-35 122.3 6.7 1.8 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFH44458.1 - 9.2e-24 83.5 0.0 2.2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFH44458.1 - 6.7e-14 51.7 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFH44458.1 - 1.8e-09 37.9 0.7 4.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFH44458.1 - 1.8e-06 27.9 0.1 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MARVEL PF01284.23 KFH44459.1 - 0.00058 19.9 17.9 0.0086 16.1 18.0 2.2 1 1 0 1 1 1 1 Membrane-associating domain DUF4834 PF16118.5 KFH44459.1 - 0.57 11.2 0.1 0.57 11.2 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Thioredoxin_4 PF13462.6 KFH44462.1 - 0.0041 17.3 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KFH44462.1 - 0.037 13.8 1.3 1.3 8.8 0.2 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Hemerythrin PF01814.23 KFH44464.1 - 7.1e-08 33.1 0.6 1.1e-07 32.5 0.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chromate_transp PF02417.15 KFH44465.1 - 5.3e-57 192.3 36.0 1.6e-33 116.1 15.5 2.4 3 0 0 3 3 3 2 Chromate transporter DUF2955 PF11168.8 KFH44465.1 - 0.049 13.5 10.2 0.15 11.9 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) NADHdh-2_N PF12155.8 KFH44465.1 - 0.091 13.2 2.2 0.19 12.1 0.9 2.2 1 1 1 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal Cation_ATPase_C PF00689.21 KFH44465.1 - 0.69 9.6 5.8 1.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus CcmH PF03918.14 KFH44465.1 - 6.8 6.0 4.9 2.4 7.4 0.2 2.4 3 0 0 3 3 3 0 Cytochrome C biogenesis protein zf-C2H2 PF00096.26 KFH44466.1 - 6.7e-05 23.1 0.6 6.7e-05 23.1 0.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH44466.1 - 0.023 15.5 6.5 0.082 13.8 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3 PF13878.6 KFH44466.1 - 0.034 14.0 0.1 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO DUF4798 PF16055.5 KFH44466.1 - 0.2 11.9 4.1 0.38 11.0 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) FeS_assembly_P PF01883.19 KFH44467.1 - 2.6e-06 27.5 0.0 2e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF2236 PF09995.9 KFH44468.1 - 4.1e-44 151.5 1.0 6.3e-44 150.9 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) SAS4 PF15460.6 KFH44469.1 - 2.2e-32 111.1 0.1 6.4e-32 109.6 0.1 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.9 KFH44469.1 - 0.024 15.2 5.1 0.081 13.5 5.1 1.9 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Astro_capsid_p PF12226.8 KFH44469.1 - 0.53 9.4 5.7 0.84 8.7 5.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KFH44469.1 - 1.4 7.2 9.7 2.1 6.5 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Fasciclin PF02469.22 KFH44470.1 - 0.0051 17.0 0.0 0.0079 16.4 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain Sin3a_C PF16879.5 KFH44471.1 - 7.8e-76 255.5 1.8 7.8e-76 255.5 1.8 3.0 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 KFH44471.1 - 8.6e-40 134.6 11.9 5.7e-18 64.8 0.0 4.6 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KFH44471.1 - 2.6e-39 133.2 0.0 8.1e-39 131.6 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor DUF775 PF05603.12 KFH44471.1 - 0.26 10.8 2.4 0.7 9.4 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) TSP_NTD PF17804.1 KFH44471.1 - 0.3 11.3 10.9 0.11 12.7 0.6 3.2 3 0 0 3 3 3 0 Tail specific protease N-terminal domain WD40 PF00400.32 KFH44472.1 - 1.4e-08 35.2 9.3 0.02 15.8 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat LicD PF04991.13 KFH44473.1 - 6.7e-19 68.9 7.1 2e-14 54.3 3.4 2.1 1 1 1 2 2 2 2 LicD family Pkinase PF00069.25 KFH44474.1 - 1.3e-21 77.1 0.0 2.8e-20 72.8 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44474.1 - 0.0004 19.7 0.6 0.031 13.5 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Zip PF02535.22 KFH44475.1 - 6.6e-53 180.1 0.2 1.1e-52 179.4 0.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Alpha-amylase PF00128.24 KFH44476.1 - 2.6e-119 398.7 1.1 2.8e-119 398.6 0.2 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFH44476.1 - 1.7e-07 31.2 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFH44476.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KFH44476.1 - 0.01 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.8 KFH44476.1 - 0.028 14.7 0.0 0.078 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_transf_22 PF03901.17 KFH44477.1 - 1.6e-42 146.2 17.3 2.2e-42 145.8 17.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF962 PF06127.11 KFH44479.1 - 4.5e-28 97.2 2.1 6.3e-28 96.7 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MARVEL PF01284.23 KFH44479.1 - 0.35 10.9 6.0 0.16 12.0 1.6 2.0 1 1 1 2 2 2 0 Membrane-associating domain Promethin PF16015.5 KFH44479.1 - 4 7.4 10.2 0.057 13.3 2.5 1.9 2 1 0 2 2 2 0 Promethin UCH PF00443.29 KFH44480.1 - 5.7e-53 180.0 1.2 6.2e-53 179.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH44480.1 - 1.1e-23 84.4 7.8 1.7e-20 73.9 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF5427 PF10310.9 KFH44480.1 - 0.21 10.5 15.3 0.36 9.7 15.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF809 PF05663.11 KFH44480.1 - 0.52 10.4 5.2 1.1 9.4 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Peptidase_C98 PF15499.6 KFH44480.1 - 2 7.8 11.2 1.4 8.3 3.8 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CDC45 PF02724.14 KFH44480.1 - 4.6 5.4 14.6 7.4 4.7 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KFH44480.1 - 4.6 5.7 14.8 6.5 5.2 14.8 1.1 1 0 0 1 1 1 0 Macoilin family AP-5_subunit_s1 PF15001.6 KFH44480.1 - 7 6.6 7.3 16 5.4 7.3 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Nucleo_P87 PF07267.11 KFH44480.1 - 7.9 5.2 15.7 13 4.5 15.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rep_fac_C PF08542.11 KFH44481.1 - 9.8e-21 74.0 0.0 2.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFH44481.1 - 4e-16 59.7 0.0 1.5e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFH44481.1 - 5.6e-12 45.7 0.0 7.2e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KFH44481.1 - 1.5e-05 25.3 0.1 0.00048 20.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFH44481.1 - 3.3e-05 23.8 0.1 7.3e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFH44481.1 - 3.4e-05 23.7 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFH44481.1 - 4.2e-05 23.8 0.1 0.00013 22.2 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KFH44481.1 - 4.3e-05 24.0 0.0 0.00053 20.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KFH44481.1 - 6.4e-05 22.9 0.2 0.43 10.5 0.1 2.6 1 1 1 2 2 2 2 Rad17 P-loop domain RuvB_N PF05496.12 KFH44481.1 - 0.00074 19.3 0.1 0.0035 17.1 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFH44481.1 - 0.001 18.5 0.0 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFH44481.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH44481.1 - 0.0017 18.7 0.0 0.014 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFH44481.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFH44481.1 - 0.0055 16.0 0.0 0.0099 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KFH44481.1 - 0.0081 15.7 0.0 0.021 14.3 0.0 1.6 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFH44481.1 - 0.01 15.6 0.0 0.042 13.6 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 KFH44481.1 - 0.01 15.8 0.0 0.043 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFH44481.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFH44481.1 - 0.032 14.2 0.0 0.25 11.3 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KFH44481.1 - 0.046 14.3 0.0 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KFH44481.1 - 0.05 13.4 0.1 0.9 9.3 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.13 KFH44481.1 - 0.068 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KFH44481.1 - 0.078 12.8 0.0 0.51 10.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFH44481.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFH44481.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFH44481.1 - 0.12 12.8 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.16 KFH44482.1 - 6.2e-162 536.8 0.1 1.7e-91 305.9 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFH44482.1 - 1.2e-50 171.8 0.1 4.9e-29 101.3 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KFH44482.1 - 2.1e-35 121.2 0.3 7e-35 119.6 0.3 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KFH44482.1 - 9.3e-25 87.6 0.0 1.4e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH44482.1 - 1.4e-10 41.4 0.0 4.9e-08 33.3 0.0 3.8 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFH44482.1 - 1.3e-07 31.9 0.0 0.011 16.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFH44482.1 - 0.00091 18.7 0.0 0.11 11.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KFH44482.1 - 0.0045 16.1 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KFH44482.1 - 0.035 13.6 0.0 4 6.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 KFH44482.1 - 0.12 11.9 0.0 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 KFH44482.1 - 0.18 11.6 0.1 11 5.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain TFIIE_alpha PF02002.17 KFH44482.1 - 0.58 10.0 3.8 3.4 7.6 0.0 3.8 4 0 0 4 4 4 0 TFIIE alpha subunit zf-HIT PF04438.16 KFH44483.1 - 1.1e-09 37.9 4.4 1.7e-09 37.4 4.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zinc_ribbon_2 PF13240.6 KFH44483.1 - 1.1 9.0 3.3 22 5.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 KFH44484.1 - 4.9e-05 24.0 0.1 0.00023 21.9 0.1 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF2415 PF10313.9 KFH44484.1 - 0.0001 22.1 0.0 0.00041 20.2 0.0 2.1 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Med13_C PF06333.12 KFH44484.1 - 3 7.0 6.7 1.1 8.4 3.9 1.6 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Fungal_trans_2 PF11951.8 KFH44485.1 - 3.2e-11 42.7 0.8 3.6e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KFH44486.1 - 8.1e-32 110.5 22.7 8.1e-32 110.5 22.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sec66 PF09802.9 KFH44487.1 - 1.1e-79 266.2 0.4 1.3e-79 266.0 0.4 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PEP-utilisers_N PF05524.13 KFH44487.1 - 0.022 14.9 0.6 0.038 14.2 0.5 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF3848 PF12959.7 KFH44487.1 - 0.034 14.2 0.2 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) RNB PF00773.19 KFH44488.1 - 8.9e-50 169.9 0.0 1.3e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain PWWP PF00855.17 KFH44489.1 - 3.1e-15 56.3 0.4 1.7e-14 54.0 0.0 2.6 2 0 0 2 2 2 1 PWWP domain ORC3_N PF07034.11 KFH44490.1 - 2.8e-39 135.1 1.9 2.4e-37 128.8 1.9 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFH44490.1 - 1.5e-26 93.2 5.9 1e-15 58.1 0.0 3.5 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal AP4E_app_platf PF14807.6 KFH44490.1 - 0.05 14.0 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Met_10 PF02475.16 KFH44491.1 - 2.5e-71 239.5 0.0 3.3e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Complex1_LYR PF05347.15 KFH44492.1 - 1.4e-13 50.7 0.5 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Cu_amine_oxidN2 PF02727.16 KFH44493.1 - 0.0069 16.6 0.0 0.0085 16.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF836 PF05768.14 KFH44494.1 - 5.6e-13 49.1 0.0 6.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KFH44494.1 - 0.0067 16.6 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFH44494.1 - 0.034 14.6 0.0 0.098 13.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Dus PF01207.17 KFH44495.1 - 3.9e-32 111.6 0.0 2.5e-27 95.8 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3602 PF12223.8 KFH44496.1 - 4.4e-21 75.3 15.7 5.3e-21 75.0 7.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) FAA_hydrolase PF01557.18 KFH44497.1 - 3e-65 219.9 0.0 4.2e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KFH44497.1 - 0.0078 16.6 0.1 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Type II transport protein GspH BAH PF01426.18 KFH44498.1 - 0.0094 15.8 0.0 0.025 14.4 0.0 1.7 2 0 0 2 2 2 1 BAH domain zf-RING-like PF08746.11 KFH44498.1 - 0.028 14.7 0.4 0.075 13.4 0.4 1.7 1 0 0 1 1 1 0 RING-like domain BAR_3_WASP_bdg PF10456.9 KFH44498.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein PHD PF00628.29 KFH44498.1 - 0.75 9.7 9.0 0.042 13.8 3.2 1.9 2 0 0 2 2 2 0 PHD-finger Thioredoxin PF00085.20 KFH44499.1 - 1.4e-63 211.3 4.1 2.2e-30 104.7 0.1 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KFH44499.1 - 5e-48 163.5 0.3 1.7e-34 119.4 0.1 3.9 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFH44499.1 - 3.1e-10 40.3 0.0 0.0058 16.9 0.0 4.5 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 KFH44499.1 - 1.5e-08 34.1 0.4 1.5e-08 34.1 0.4 2.2 3 1 0 3 3 3 1 Calsequestrin OST3_OST6 PF04756.13 KFH44499.1 - 1.6e-08 34.3 0.5 0.0026 17.2 0.0 3.1 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFH44499.1 - 1.1e-07 31.9 0.0 0.0038 17.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFH44499.1 - 3.5e-07 30.2 0.3 0.086 12.8 0.1 3.5 2 2 1 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KFH44499.1 - 5.7e-07 30.0 0.5 0.0087 16.5 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 KFH44499.1 - 0.00016 21.4 1.3 0.1 12.3 0.0 3.4 3 1 1 4 4 4 2 Redoxin Thioredoxin_4 PF13462.6 KFH44499.1 - 0.013 15.7 1.6 0.98 9.6 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.6 KFH44499.1 - 0.027 14.5 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain DSBA PF01323.20 KFH44499.1 - 0.09 12.5 0.2 24 4.6 0.0 3.0 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Ribosomal_60s PF00428.19 KFH44499.1 - 1.6 9.3 10.4 0.27 11.8 3.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein ICL PF00463.21 KFH44500.1 - 5.8e-123 411.2 1.2 6.9e-123 410.9 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFH44500.1 - 4.4e-06 26.3 0.0 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase GAS PF13851.6 KFH44500.1 - 0.14 11.5 0.4 0.25 10.6 0.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med13_C PF06333.12 KFH44501.1 - 0.25 10.5 13.6 0.3 10.3 13.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain FSA_C PF10479.9 KFH44501.1 - 0.78 7.8 5.1 0.92 7.6 5.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 KFH44501.1 - 3 5.7 3.5 3.5 5.5 3.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Prenyltransf PF01255.19 KFH44502.1 - 1.1e-08 34.9 0.0 6e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 KFH44502.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) RTC4 PF14474.6 KFH44503.1 - 1e-30 106.4 0.0 2.3e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain DUF1648 PF07853.11 KFH44503.1 - 0.022 14.4 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) XRCC4 PF06632.12 KFH44503.1 - 0.11 11.4 5.4 0.2 10.5 5.4 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 2OG-FeII_Oxy_2 PF13532.6 KFH44504.1 - 2.6e-27 96.3 0.0 3.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 KFH44505.1 - 5.2e-47 160.8 0.0 1e-46 159.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFH44505.1 - 3.6e-06 26.5 0.1 6.9e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFH44505.1 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFH44505.1 - 0.0057 16.3 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 KFH44505.1 - 0.0095 14.8 0.0 0.04 12.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) PP2C PF00481.21 KFH44506.1 - 1.5e-56 191.9 0.0 2.8e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KFH44506.1 - 2.2e-40 136.2 54.5 8.9e-09 35.0 0.3 9.9 4 3 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFH44506.1 - 5.4e-38 128.4 67.0 7.8e-05 23.0 0.4 12.7 10 2 2 13 13 13 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KFH44506.1 - 1e-30 106.8 0.0 5.7e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KFH44506.1 - 4.1e-18 64.8 1.7 1.3e-17 63.2 1.7 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KFH44506.1 - 2e-05 24.5 52.9 6.4 7.7 0.1 16.7 16 2 1 17 17 17 2 Leucine Rich Repeat LRR_6 PF13516.6 KFH44506.1 - 6.4e-05 22.7 42.6 1.9 8.7 0.0 12.0 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.6 KFH44506.1 - 0.00045 19.8 19.7 0.056 12.9 1.1 4.6 2 1 1 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KFH44506.1 - 0.26 11.2 4.2 2.8 7.9 0.3 3.2 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Yos1 PF08571.10 KFH44507.1 - 2.4e-33 114.2 0.3 2.7e-33 114.1 0.3 1.0 1 0 0 1 1 1 1 Yos1-like Hydantoinase_B PF02538.14 KFH44508.1 - 1.5e-200 667.0 2.1 2e-200 666.6 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFH44508.1 - 9.4e-97 323.8 0.7 3.5e-96 321.9 0.1 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFH44508.1 - 4.8e-57 192.5 0.1 3.4e-55 186.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pyr_redox_2 PF07992.14 KFH44508.1 - 0.014 14.6 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Proteasome_A_N PF10584.9 KFH44508.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SHS2_Rpb7-N PF03876.17 KFH44509.1 - 1.6e-15 57.2 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFH44509.1 - 8.5e-15 54.9 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KFH44509.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 Serglycin PF04360.12 KFH44510.1 - 0.98 9.4 3.1 2.1 8.3 3.1 1.5 1 0 0 1 1 1 0 Serglycin Mito_carr PF00153.27 KFH44511.1 - 5.6e-48 160.8 7.2 1.1e-17 63.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.26 KFH44512.1 - 1.6e-38 131.6 0.0 3.7e-25 88.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH44512.1 - 6.7e-06 25.8 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 Prokaryotic E2 family B DUF4362 PF14275.6 KFH44512.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) tRNA-synt_2b PF00587.25 KFH44513.1 - 1.1e-32 113.4 0.0 2.3e-30 105.9 0.0 3.4 3 1 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFH44513.1 - 4.8e-17 61.9 0.1 9.9e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KFH44513.1 - 2.6e-11 43.4 0.0 9.2e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KFH44513.1 - 4.7e-10 39.4 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain NPL4 PF05021.15 KFH44516.1 - 2.2e-137 457.5 0.0 3e-137 457.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFH44516.1 - 3.1e-67 225.2 0.0 4.9e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFH44516.1 - 0.0016 18.9 0.0 0.0036 17.7 0.0 1.6 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Trypan_PARP PF05887.11 KFH44517.1 - 0.2 11.6 39.7 0.46 10.5 2.7 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 KFH44517.1 - 6 7.3 7.0 0.83 10.1 2.4 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1752 PF08550.10 KFH44519.1 - 1.1e-11 44.4 4.2 2.4e-11 43.2 4.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Exonuc_VII_S PF02609.16 KFH44520.1 - 0.015 15.4 0.8 0.049 13.7 0.6 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit ThiS PF02597.20 KFH44521.1 - 3.9e-09 37.0 0.0 1.4e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 ThiS family Lambda_tail_I PF06805.12 KFH44521.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I CPSase_L_D2 PF02786.17 KFH44523.1 - 3.9e-112 372.9 0.1 3e-85 285.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFH44523.1 - 9.8e-41 138.9 0.0 3.2e-40 137.3 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KFH44523.1 - 6.2e-23 81.2 0.2 8.7e-12 44.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFH44523.1 - 4.5e-20 72.1 1.1 1.4e-09 37.8 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFH44523.1 - 1.6e-12 47.3 0.0 1.2e-05 25.0 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KFH44523.1 - 9.8e-07 28.7 0.6 0.048 13.4 0.2 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KFH44523.1 - 9.1e-06 25.8 1.1 0.15 12.1 0.1 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KFH44523.1 - 1.7e-05 24.4 0.1 0.096 12.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KFH44523.1 - 0.00051 19.7 0.2 0.011 15.3 0.1 2.9 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KFH44523.1 - 0.14 11.7 0.5 7.7 6.0 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain Sec10 PF07393.11 KFH44524.1 - 2.3e-226 753.6 4.3 2.8e-226 753.3 4.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Methyltransf_23 PF13489.6 KFH44524.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HpcH_HpaI PF03328.14 KFH44525.1 - 2.2e-33 115.3 0.1 2.7e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 KFH44525.1 - 0.00034 20.2 0.2 0.081 12.4 0.0 3.0 2 1 1 3 3 3 2 Phosphoenolpyruvate phosphomutase IBR PF01485.21 KFH44526.1 - 2.1e-08 34.3 31.5 1.5e-06 28.4 13.7 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Aromatic_hydrox PF11723.8 KFH44526.1 - 0.06 12.8 0.9 0.11 11.9 0.9 1.4 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase CHORD PF04968.12 KFH44527.1 - 7.2e-49 164.4 18.2 2.2e-24 86.0 7.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KFH44527.1 - 1.1e-12 48.7 0.0 1.7e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 CS domain CAP_N PF01213.19 KFH44527.1 - 4.7 6.6 5.8 6.7 6.1 5.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATG22 PF11700.8 KFH44529.1 - 7.7e-192 638.2 10.6 8.9e-192 637.9 10.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TRAP-gamma PF07074.12 KFH44529.1 - 0.0092 15.6 0.8 0.021 14.4 0.8 1.5 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Fungal_trans PF04082.18 KFH44530.1 - 1.6e-15 56.9 2.7 2.3e-15 56.4 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44530.1 - 7.4e-08 32.4 11.4 1.4e-07 31.5 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pinin_SDK_N PF04697.13 KFH44530.1 - 0.023 15.3 2.2 0.023 15.3 2.2 2.1 2 0 0 2 2 2 0 pinin/SDK conserved region F_actin_cap_B PF01115.17 KFH44531.1 - 2.6e-103 344.8 0.0 3e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Aminotran_1_2 PF00155.21 KFH44533.1 - 4.6e-15 55.6 0.0 8.3e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFH44533.1 - 0.0068 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Acyl-CoA_dh_1 PF00441.24 KFH44534.1 - 2.7e-35 121.8 0.6 4.4e-35 121.1 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH44534.1 - 1.5e-15 57.2 0.0 2.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFH44534.1 - 1.3e-10 41.7 0.5 2.5e-10 40.7 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH44534.1 - 1.1e-06 29.2 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KFH44534.1 - 0.029 14.0 0.0 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Dynamitin PF04912.14 KFH44535.1 - 3.8e-115 385.3 4.7 4.3e-115 385.2 4.7 1.0 1 0 0 1 1 1 1 Dynamitin Fzo_mitofusin PF04799.13 KFH44535.1 - 0.0094 15.5 3.7 0.19 11.3 0.0 3.0 3 0 0 3 3 3 1 fzo-like conserved region FH2 PF02181.23 KFH44535.1 - 0.0099 15.0 5.4 0.38 9.8 0.1 2.6 3 0 0 3 3 3 2 Formin Homology 2 Domain Spore_III_AB PF09548.10 KFH44535.1 - 0.023 14.8 3.4 0.1 12.7 0.1 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DHR10 PF18595.1 KFH44535.1 - 0.039 14.0 14.0 1.6 8.8 0.4 3.7 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 KFH44535.1 - 0.041 13.7 0.3 0.041 13.7 0.3 3.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 Laminin_II PF06009.12 KFH44535.1 - 0.049 13.6 9.0 0.15 12.1 0.4 3.7 3 1 1 4 4 4 0 Laminin Domain II THOC7 PF05615.13 KFH44535.1 - 0.056 13.7 8.6 1.4 9.2 1.5 3.2 3 0 0 3 3 3 0 Tho complex subunit 7 DivIC PF04977.15 KFH44535.1 - 0.087 12.6 15.3 1.5 8.7 0.6 3.5 3 0 0 3 3 3 0 Septum formation initiator Baculo_PEP_C PF04513.12 KFH44535.1 - 0.14 12.2 0.2 6.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 KFH44535.1 - 0.14 11.9 4.0 2.5 7.9 0.2 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Rotamase PF00639.21 KFH44535.1 - 0.16 12.9 5.4 1.7 9.6 0.2 3.1 3 0 0 3 3 2 0 PPIC-type PPIASE domain Snapin_Pallidin PF14712.6 KFH44535.1 - 0.2 12.1 9.0 4.6 7.7 0.4 4.7 3 2 0 3 3 3 0 Snapin/Pallidin YabA PF06156.13 KFH44535.1 - 0.21 12.2 3.7 3.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Initiation control protein YabA SOGA PF11365.8 KFH44535.1 - 0.27 12.4 6.7 1.2 10.4 0.3 3.4 3 1 0 3 3 3 0 Protein SOGA GrpE PF01025.19 KFH44535.1 - 0.28 10.8 10.5 1.3 8.6 1.3 3.5 2 1 1 3 3 3 0 GrpE DUF724 PF05266.14 KFH44535.1 - 0.3 10.9 6.1 3.2 7.5 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ATP-synt_E PF05680.12 KFH44535.1 - 0.38 11.1 0.1 0.38 11.1 0.1 3.1 3 0 0 3 3 3 0 ATP synthase E chain Cytochrom_B562 PF07361.11 KFH44535.1 - 0.53 11.0 8.1 4.5 8.0 0.4 3.3 3 0 0 3 3 3 0 Cytochrome b562 Fib_alpha PF08702.10 KFH44535.1 - 0.73 10.0 5.1 6.4 7.0 0.1 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HWE_HK PF07536.14 KFH44535.1 - 0.76 10.5 3.5 0.79 10.5 0.8 2.5 2 0 0 2 2 1 0 HWE histidine kinase Spc24 PF08286.11 KFH44535.1 - 0.82 9.9 8.7 2.6 8.3 0.4 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 KFH44535.1 - 0.83 9.9 7.0 0.9 9.8 0.3 3.0 2 1 1 3 3 3 0 Zinc finger-containing protein LPP PF04728.13 KFH44535.1 - 0.97 9.9 5.2 16 6.0 0.1 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ZapB PF06005.12 KFH44535.1 - 1 9.8 12.9 2.9 8.4 0.4 3.5 3 0 0 3 3 3 0 Cell division protein ZapB Syntaxin_2 PF14523.6 KFH44535.1 - 1.2 9.5 3.4 26 5.3 0.1 3.1 3 0 0 3 3 3 0 Syntaxin-like protein OmpH PF03938.14 KFH44535.1 - 1.9 8.9 11.1 8.4 6.7 1.1 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KFH44535.1 - 2 8.5 16.8 0.45 10.6 1.2 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 KFH44535.1 - 2.3 8.3 13.0 9.4 6.4 0.8 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase MRPL52 PF18699.1 KFH44535.1 - 2.8 8.2 7.5 0.57 10.4 0.1 3.0 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Prefoldin_2 PF01920.20 KFH44535.1 - 4 7.4 10.0 10 6.1 0.2 3.9 3 1 1 4 4 4 0 Prefoldin subunit Cluap1 PF10234.9 KFH44535.1 - 6.1 6.2 11.0 3.1 7.1 0.5 3.0 3 0 0 3 3 3 0 Clusterin-associated protein-1 FliD_N PF02465.18 KFH44535.1 - 7.8 7.3 7.2 1.6 9.5 0.6 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MIP-T3_C PF17749.1 KFH44535.1 - 7.9 6.4 9.9 14 5.6 2.1 3.2 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1192 PF06698.11 KFH44535.1 - 8.7 6.5 13.5 0.4 10.8 3.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Chitin_synth_2 PF03142.15 KFH44536.1 - 4.1e-232 771.5 0.1 5.8e-232 771.0 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KFH44536.1 - 1.1e-14 54.1 1.5 6.5e-14 51.6 2.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KFH44536.1 - 2e-14 54.0 1.8 2e-14 54.0 1.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFH44536.1 - 2.7e-13 50.3 0.0 2.2e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 KFH44536.1 - 6e-12 45.5 4.4 4.3e-10 39.6 0.1 3.5 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 KFH44536.1 - 5e-08 31.6 0.0 3.3e-07 28.9 0.0 1.9 1 1 1 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KFH44536.1 - 8.8e-05 22.0 0.0 0.00047 19.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFH44536.1 - 0.00023 21.0 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.20 KFH44537.1 - 2e-169 564.6 7.8 2e-169 564.6 7.8 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KFH44537.1 - 4.8e-13 48.6 0.0 3.8e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFH44537.1 - 0.023 15.1 0.4 13 6.3 0.0 3.3 2 1 0 2 2 2 0 Cell division protein FtsA Fungal_trans PF04082.18 KFH44538.1 - 1.2e-25 90.1 0.0 1.1e-24 87.0 0.0 2.5 2 2 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44538.1 - 2.2e-08 34.1 9.0 3.9e-08 33.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.6 KFH44538.1 - 0.021 15.0 0.2 0.037 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) IHABP4_N PF16174.5 KFH44538.1 - 2.2 8.9 9.7 5.6 7.5 9.7 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal His_Phos_2 PF00328.22 KFH44539.1 - 3.4e-62 211.0 0.0 3.9e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MIF4G PF02854.19 KFH44540.1 - 2.5e-55 187.4 0.1 1.2e-27 96.9 0.0 4.5 5 1 0 5 5 5 3 MIF4G domain Upf2 PF04050.14 KFH44540.1 - 9.7e-43 146.2 10.3 9.7e-43 146.2 10.3 2.8 3 0 0 3 3 3 1 Up-frameshift suppressor 2 RseA_C PF03873.13 KFH44540.1 - 0.071 13.4 1.9 0.21 11.8 1.9 1.9 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain TCTP PF00838.17 KFH44540.1 - 3.3 8.0 7.5 0.86 9.9 0.0 3.1 3 0 0 3 3 3 0 Translationally controlled tumour protein Fib_alpha PF08702.10 KFH44540.1 - 3.5 7.8 6.8 0.23 11.6 0.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ran_BP1 PF00638.18 KFH44541.1 - 4.2e-13 49.6 0.1 1.5e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain Glyco_hydro_75 PF07335.11 KFH44541.1 - 0.0064 16.8 0.0 0.09 13.1 0.0 2.2 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 MARVEL PF01284.23 KFH44542.1 - 2.8e-05 24.2 20.1 4.2e-05 23.6 20.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1980 PF09323.10 KFH44542.1 - 0.0048 16.8 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Npa1 PF11707.8 KFH44543.1 - 1.4e-99 333.7 0.0 2.7e-99 332.8 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFH44543.1 - 2.9e-63 213.1 0.4 2.4e-62 210.1 0.1 2.5 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 DUF1729 PF08354.10 KFH44544.1 - 1.7e-157 523.9 0.0 2.7e-157 523.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KFH44544.1 - 2.4e-90 303.3 0.0 1.6e-88 297.3 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 KFH44544.1 - 1.6e-54 183.7 0.0 4.1e-54 182.4 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KFH44544.1 - 3.6e-37 127.3 0.0 1.1e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KFH44544.1 - 4.7e-37 126.3 0.0 1e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KFH44544.1 - 1.3e-32 113.4 0.0 4.1e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KFH44544.1 - 5.7e-25 88.0 0.0 2.5e-24 85.9 0.0 2.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PLA2_B PF01735.18 KFH44545.1 - 6.1e-29 100.8 0.0 9.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.10 KFH44545.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 NgoPII restriction endonuclease LSM PF01423.22 KFH44546.1 - 8.7e-17 60.6 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFH44546.1 - 0.0088 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain GTP_EFTU PF00009.27 KFH44547.1 - 4.5e-34 117.7 1.0 9.9e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFH44547.1 - 1.8e-19 69.8 0.0 4.8e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KFH44547.1 - 4e-11 43.1 4.9 1.1e-07 32.2 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KFH44547.1 - 7.3e-10 38.6 0.2 2.1e-09 37.1 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KFH44547.1 - 1.8e-07 31.3 0.2 8.8e-06 25.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFH44547.1 - 0.00019 21.7 0.0 0.00098 19.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TrkA_C PF02080.21 KFH44547.1 - 0.014 15.2 0.4 3.3 7.6 0.0 3.3 3 0 0 3 3 3 0 TrkA-C domain Inositol_P PF00459.25 KFH44548.1 - 2.3e-60 204.4 0.0 2.8e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.32 KFH44549.1 - 4.3e-12 46.3 13.9 0.0082 17.0 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44549.1 - 0.052 13.9 0.2 64 3.9 0.0 3.9 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 KFH44550.1 - 7.8e-60 202.9 0.0 1.8e-59 201.7 0.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFH44550.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region Vps52 PF04129.12 KFH44551.1 - 7.5e-122 407.7 0.1 9.5e-122 407.3 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KFH44551.1 - 1.2e-05 24.0 2.7 2.6e-05 22.9 2.6 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF4795 PF16043.5 KFH44551.1 - 0.0075 15.9 1.0 0.015 14.9 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Mer2 PF09074.10 KFH44551.1 - 0.018 14.9 0.2 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Mer2 Exo70 PF03081.15 KFH44551.1 - 0.018 14.1 0.0 0.075 12.1 0.0 2.0 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Ribosomal_S21 PF01165.20 KFH44551.1 - 0.078 12.7 0.2 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S21 ETC_C1_NDUFA5 PF04716.14 KFH44552.1 - 1.4e-25 88.8 5.1 9.8e-24 83.0 0.0 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region zf-RING_2 PF13639.6 KFH44553.1 - 3e-14 53.1 16.9 4.7e-13 49.2 7.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KFH44553.1 - 1.2e-11 44.2 10.4 7.1e-09 35.4 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH44553.1 - 3.6e-11 42.6 6.9 4e-11 42.4 3.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFH44553.1 - 6.9e-10 38.6 14.5 1.3e-09 37.7 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH44553.1 - 7.5e-08 32.1 14.3 6e-07 29.2 5.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH44553.1 - 9.1e-07 29.1 6.8 9.1e-07 29.1 6.8 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFH44553.1 - 3.9e-06 26.7 2.8 3.9e-06 26.7 2.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH44553.1 - 3.4e-05 23.6 12.4 0.00016 21.4 5.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFH44553.1 - 4e-05 23.6 0.8 4e-05 23.6 0.8 2.8 2 2 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFH44553.1 - 0.006 16.6 2.3 0.006 16.6 2.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 KFH44553.1 - 0.017 15.4 5.7 0.037 14.3 2.9 2.5 2 0 0 2 2 2 0 zinc-ribbon HypA PF01155.19 KFH44553.1 - 0.019 15.0 0.1 0.019 15.0 0.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 KFH44553.1 - 0.023 14.8 0.6 0.023 14.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-FPG_IleRS PF06827.14 KFH44553.1 - 0.03 14.2 0.9 3.1 7.7 0.1 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PhnA_Zn_Ribbon PF08274.12 KFH44553.1 - 0.04 13.9 4.5 0.53 10.3 0.3 2.6 1 1 1 2 2 2 0 PhnA Zinc-Ribbon PHD PF00628.29 KFH44553.1 - 0.13 12.2 12.1 0.16 11.9 4.9 2.6 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KFH44553.1 - 0.15 11.7 14.8 0.034 13.7 5.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFH44553.1 - 0.16 11.8 13.7 0.21 11.4 4.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ATG11 PF10377.9 KFH44553.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 RINGv PF12906.7 KFH44553.1 - 0.27 11.4 15.3 0.034 14.3 7.7 2.4 2 0 0 2 2 2 0 RING-variant domain DZR PF12773.7 KFH44553.1 - 0.32 11.1 5.1 4.6 7.3 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Baculo_RING PF05883.11 KFH44553.1 - 0.61 10.1 1.9 1.1 9.3 0.6 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zinc-ribbons_6 PF07191.12 KFH44553.1 - 0.87 9.6 8.2 1.6 8.8 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbons zf-C3HC4_4 PF15227.6 KFH44553.1 - 1.1 9.5 11.0 1 9.6 1.0 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf_Rg PF17915.1 KFH44553.1 - 1.6 8.2 7.6 0.22 11.0 0.4 2.6 3 0 0 3 3 3 0 Reverse gyrase zinc finger Prok-RING_1 PF14446.6 KFH44553.1 - 4.5 7.3 12.5 19 5.3 0.6 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.6 KFH44553.1 - 7.6 6.5 5.9 1.3 8.9 0.9 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RRN7 PF11781.8 KFH44554.1 - 0.00013 21.6 1.9 0.00024 20.7 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rhodanese PF00581.20 KFH44555.1 - 1.9e-15 57.3 0.0 3.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Fungal_trans PF04082.18 KFH44556.1 - 4.4e-39 134.1 0.0 8.6e-39 133.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44556.1 - 4.3e-08 33.1 6.9 9.7e-08 32.0 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 KFH44557.1 - 3.4e-15 56.3 0.0 5.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF883 PF05957.13 KFH44557.1 - 0.1 13.2 0.1 0.3 11.7 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Inhibitor_I9 PF05922.16 KFH44558.1 - 4e-11 43.4 0.5 5.8e-11 42.9 0.5 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 KFH44558.1 - 0.012 15.4 0.2 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain DEAD PF00270.29 KFH44559.1 - 1.5e-27 96.5 0.0 2.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KFH44559.1 - 1.1e-22 80.5 0.3 3.2e-22 79.1 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KFH44559.1 - 9.4e-11 42.0 0.0 5.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH44559.1 - 2.6e-07 30.8 0.0 4.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KFH44559.1 - 3.5e-06 27.4 0.0 7.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like AAA PF00004.29 KFH44560.1 - 2.8e-10 40.7 0.0 5.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH44560.1 - 7.6e-07 29.5 0.0 2.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFH44560.1 - 3.3e-05 23.9 0.0 7.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KFH44560.1 - 3.4e-05 23.9 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFH44560.1 - 9.8e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFH44560.1 - 0.00022 21.4 0.3 0.00082 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH44560.1 - 0.00043 20.7 1.0 0.0067 16.8 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_30 PF13604.6 KFH44560.1 - 0.003 17.3 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFH44560.1 - 0.0041 17.1 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH44560.1 - 0.016 15.8 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFH44560.1 - 0.037 13.9 0.4 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KFH44560.1 - 0.04 13.1 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KFH44560.1 - 0.057 13.3 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KFH44560.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFH44560.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFH44560.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFH44560.1 - 0.19 11.2 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region BRO1 PF03097.18 KFH44561.1 - 1.2e-135 452.3 3.2 2.6e-135 451.2 3.2 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFH44561.1 - 1.8e-77 260.6 20.4 4.3e-77 259.3 20.4 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 KFH44561.1 - 1 9.5 10.1 0.04 14.0 0.7 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GLTP PF08718.11 KFH44562.1 - 6.3e-47 159.6 0.0 8.6e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Chitin_synth_2 PF03142.15 KFH44563.1 - 1.2e-247 822.7 1.0 1.6e-247 822.3 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KFH44563.1 - 1.5e-69 234.9 0.0 5.9e-69 233.0 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KFH44563.1 - 9.8e-16 57.4 0.0 3.9e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KFH44563.1 - 2.4e-14 53.2 0.0 2.4e-10 40.4 0.1 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KFH44563.1 - 3.8e-12 46.5 4.6 3.8e-12 46.5 4.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFH44563.1 - 4.5e-09 36.5 0.1 1.6e-08 34.7 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFH44563.1 - 5.9e-06 26.2 0.0 0.0022 17.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KFH44563.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KFH44563.1 - 0.038 14.5 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Wzy_C PF04932.15 KFH44563.1 - 0.069 12.8 0.0 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 O-Antigen ligase AAA_16 PF13191.6 KFH44563.1 - 0.076 13.4 0.1 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Glyco_transf_21 PF13506.6 KFH44563.1 - 0.094 12.2 0.3 0.29 10.6 0.3 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 MMR_HSR1 PF01926.23 KFH44563.1 - 0.12 12.4 0.1 2 8.5 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF5451 PF17532.2 KFH44563.1 - 0.13 12.5 0.2 0.25 11.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5451) Chitin_synth_2 PF03142.15 KFH44564.1 - 2.6e-19 69.3 0.8 3.7e-19 68.7 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFH44564.1 - 4.6e-14 52.8 6.7 7.9e-14 52.0 6.7 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFH44564.1 - 0.0007 19.6 0.2 0.0012 18.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Abhydrolase_3 PF07859.13 KFH44565.1 - 4.1e-43 147.7 0.0 7e-43 146.9 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH44565.1 - 1.3e-06 27.6 0.0 4e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFH44565.1 - 3.5e-06 26.6 0.0 0.05 13.1 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFH44565.1 - 3.7e-05 24.4 1.3 5.8e-05 23.8 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFH44565.1 - 0.035 13.9 0.0 0.26 11.0 0.0 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KFH44565.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase RCR PF12273.8 KFH44566.1 - 0.13 12.9 3.4 0.5 11.0 3.4 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PPR_2 PF13041.6 KFH44567.1 - 2e-06 27.9 0.4 1.7 8.9 0.0 5.8 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.6 KFH44567.1 - 3e-06 27.2 0.0 0.12 12.4 0.0 4.3 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KFH44567.1 - 0.00018 21.5 2.2 3 8.3 0.0 6.1 6 0 0 6 6 6 1 PPR repeat COX5A PF02284.16 KFH44567.1 - 0.0009 19.2 1.7 0.21 11.6 0.0 3.4 4 0 0 4 4 4 1 Cytochrome c oxidase subunit Va PPR_long PF17177.4 KFH44567.1 - 0.018 14.4 0.1 0.72 9.2 0.1 2.4 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Sedlin_N PF04628.13 KFH44567.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region RNA_pol_I_TF PF04090.12 KFH44568.1 - 0.00029 20.4 0.0 0.0012 18.4 0.0 1.8 2 1 0 2 2 2 1 RNA polymerase I specific initiation factor Rxt3 PF08642.10 KFH44568.1 - 0.15 12.8 0.3 0.42 11.4 0.2 1.8 1 1 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1176 PF06674.11 KFH44570.1 - 5.7 6.3 4.7 3.4 7.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1176) Rib_5-P_isom_A PF06026.14 KFH44572.1 - 3.2e-45 153.8 0.0 5.8e-45 153.0 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) dsrm PF00035.26 KFH44573.1 - 7.2e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KFH44573.1 - 0.00034 20.8 0.0 0.73 10.0 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFH44573.1 - 0.018 15.7 0.0 0.068 13.8 0.0 2.0 2 1 0 2 2 2 0 Ribonuclease III domain Alpha_GJ PF03229.13 KFH44573.1 - 0.63 10.6 9.1 1.8 9.1 9.1 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Amidohydro_1 PF01979.20 KFH44574.1 - 8e-73 245.7 0.0 1.1e-72 245.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH44574.1 - 5.7e-09 36.0 2.3 7.3e-07 29.0 0.4 2.3 2 0 0 2 2 2 2 Amidohydrolase family La PF05383.17 KFH44575.1 - 6.5e-18 64.5 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFH44575.1 - 1e-09 38.1 0.2 1.9e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FXMRP1_C_core PF12235.8 KFH44575.1 - 0.018 15.7 17.8 0.018 15.7 17.8 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Yip1 PF04893.17 KFH44576.1 - 5.9e-12 45.7 12.8 8.9e-12 45.1 12.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KFH44576.1 - 0.0041 16.9 3.6 0.0066 16.2 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KFH44576.1 - 0.84 7.9 4.3 1 7.6 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NAD_binding_2 PF03446.15 KFH44577.1 - 5.1e-28 98.2 0.2 8.6e-28 97.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFH44577.1 - 2.3e-10 40.7 0.8 3.8e-10 40.1 0.8 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KFH44577.1 - 5.5e-08 33.0 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFH44577.1 - 3.2e-07 30.8 0.0 9.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 KFH44577.1 - 0.0015 19.1 0.0 0.0042 17.7 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH44577.1 - 0.0072 16.6 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KFH44577.1 - 0.014 15.7 0.1 0.063 13.5 0.0 2.1 2 1 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.6 KFH44577.1 - 0.041 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFH44577.1 - 0.077 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAS_I_H PF18314.1 KFH44578.1 - 2.9e-77 258.9 0.2 8.1e-77 257.4 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KFH44578.1 - 1.7e-75 252.8 0.3 4.9e-75 251.3 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KFH44578.1 - 2.9e-22 79.5 0.0 7.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KFH44578.1 - 1.4e-16 60.6 0.0 4.2e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KFH44578.1 - 1e-11 44.9 0.3 3.2e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KFH44578.1 - 1e-06 28.3 0.0 2.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH44578.1 - 0.00012 22.1 0.2 0.001 19.0 0.0 2.5 2 0 0 2 2 2 1 KR domain NAT PF04768.13 KFH44579.1 - 5.9e-50 169.2 0.0 1.9e-49 167.6 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Mo-co_dimer PF03404.16 KFH44580.1 - 5.3e-60 201.4 0.1 1.1e-59 200.4 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KFH44580.1 - 7.7e-56 188.4 0.0 1.9e-55 187.1 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KFH44580.1 - 1.7e-32 111.7 0.0 3.3e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFH44580.1 - 6.3e-30 104.0 0.0 1.4e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KFH44580.1 - 4e-18 65.3 0.0 1e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFH44580.1 - 0.0033 17.6 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain eIF-5a PF01287.20 KFH44582.1 - 2.9e-23 81.8 1.2 6.2e-23 80.7 1.2 1.6 1 1 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFH44582.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Yip1 PF04893.17 KFH44583.1 - 3e-12 46.6 17.1 3e-12 46.6 17.1 1.4 1 1 0 1 1 1 1 Yip1 domain GRA6 PF05084.13 KFH44583.1 - 0.011 15.7 0.3 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Granule antigen protein (GRA6) BAR_2 PF10455.9 KFH44584.1 - 4.9e-57 193.3 0.3 7.4e-57 192.7 0.3 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFH44584.1 - 1.5e-18 67.3 2.4 2.8e-17 63.2 2.4 2.3 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFH44584.1 - 0.003 17.3 1.0 0.011 15.5 0.2 2.2 2 0 0 2 2 2 1 BAR domain of APPL family GCP_C_terminal PF04130.13 KFH44584.1 - 0.07 12.6 0.2 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal p450 PF00067.22 KFH44585.1 - 3.3e-52 177.8 0.0 4.9e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S4 PF01479.25 KFH44586.1 - 3.9e-15 55.3 0.0 6.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KFH44586.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 S4 domain BCDHK_Adom3 PF10436.9 KFH44587.1 - 2.3e-45 154.3 0.0 3.4e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFH44587.1 - 5.3e-10 39.8 0.0 4.9e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KFH44587.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FMN_dh PF01070.18 KFH44588.1 - 1.1e-119 399.6 0.0 1.4e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFH44588.1 - 2.6e-22 78.7 0.1 4.9e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFH44588.1 - 1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFH44588.1 - 0.00072 18.6 0.4 0.0017 17.4 0.1 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFH44588.1 - 0.0088 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KFH44588.1 - 0.037 13.5 0.6 0.8 9.1 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein PLDc_2 PF13091.6 KFH44589.1 - 6.1e-13 48.8 0.1 2.1e-05 24.4 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KFH44589.1 - 1.1e-12 47.6 9.0 1.2e-07 31.6 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif tRNA-synt_2 PF00152.20 KFH44591.1 - 5.9e-72 242.4 0.0 8.3e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KFH44591.1 - 4.8e-14 52.1 0.2 8.1e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KFH44591.1 - 7.6e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFH44591.1 - 0.01 15.4 0.1 0.61 9.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Peptidase_S8 PF00082.22 KFH44592.1 - 1.4e-31 109.8 6.2 2.4e-31 109.1 6.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH44592.1 - 1.8e-11 44.5 0.2 8e-11 42.5 0.2 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 adh_short_C2 PF13561.6 KFH44593.1 - 1.8e-47 161.8 5.2 9.5e-39 133.3 2.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH44593.1 - 3.6e-45 153.8 1.9 4.7e-45 153.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH44593.1 - 1.9e-15 57.2 0.2 2.8e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH44593.1 - 0.0038 17.1 0.8 0.0062 16.4 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFH44593.1 - 0.041 13.9 1.2 0.071 13.2 0.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 KFH44594.1 - 1.1e-39 136.3 55.7 1.1e-39 136.3 55.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1418 PF07214.12 KFH44594.1 - 0.11 12.4 3.2 0.17 11.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) PepSY_TM_like_2 PF16357.5 KFH44594.1 - 7.5 6.5 10.1 3.3 7.7 4.3 2.6 2 0 0 2 2 2 0 Putative PepSY_TM-like AT_hook PF02178.19 KFH44595.1 - 3.3e-06 26.3 110.6 0.061 13.2 3.2 12.2 11 0 0 11 11 11 9 AT hook motif Sulfotransfer_4 PF17784.1 KFH44596.1 - 4e-75 252.3 0.1 4.9e-75 252.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH44596.1 - 1.7e-05 25.3 0.2 0.011 16.2 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family DIT1_PvcA PF05141.12 KFH44597.1 - 0.057 12.9 0.1 0.057 12.9 0.1 1.5 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DUF4407 PF14362.6 KFH44597.1 - 0.19 11.0 8.3 1.9 7.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Vps5 PF09325.10 KFH44597.1 - 0.72 9.4 14.2 0.49 9.9 0.1 3.0 2 1 1 3 3 3 0 Vps5 C terminal like Spt5_N PF11942.8 KFH44597.1 - 1.6 9.7 16.8 1.6 9.8 6.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF5349 PF17298.2 KFH44597.1 - 4.2 7.0 12.7 7 6.3 12.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) UPF0560 PF10577.9 KFH44597.1 - 8.6 4.7 14.2 3.9 5.9 9.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 AATase PF07247.12 KFH44598.1 - 8.2e-18 64.2 0.0 1.2e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KFH44598.1 - 0.00068 19.5 0.5 0.0013 18.6 0.5 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Mak_N_cap PF18085.1 KFH44598.1 - 0.027 15.5 0.7 1.1 10.3 0.1 2.7 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain DUF2267 PF10025.9 KFH44598.1 - 0.1 12.9 0.1 0.37 11.1 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Dehydrin PF00257.19 KFH44598.1 - 1.5 9.3 5.0 3 8.4 5.0 1.4 1 0 0 1 1 1 0 Dehydrin MRP-L28 PF09812.9 KFH44599.1 - 0.032 14.4 0.1 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 NST1 PF13945.6 KFH44600.1 - 1.3e-53 182.0 6.6 1.3e-53 182.0 6.6 4.9 2 2 3 5 5 5 1 Salt tolerance down-regulator TPP_enzyme_N PF02776.18 KFH44601.1 - 2e-52 177.2 0.0 4.6e-50 169.6 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFH44601.1 - 3.6e-50 169.7 0.0 9.8e-49 165.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFH44601.1 - 2.2e-41 140.8 0.3 6e-41 139.4 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_127 PF07944.12 KFH44602.1 - 4.9e-139 464.2 1.4 5.7e-139 464.0 1.4 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF5636 PF18686.1 KFH44602.1 - 0.015 15.6 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5636) DUF4986 PF16375.5 KFH44602.1 - 0.04 14.6 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function Fungal_trans PF04082.18 KFH44604.1 - 1.8e-11 43.6 0.0 4.1e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44604.1 - 4e-07 30.0 11.1 4e-07 30.0 11.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFH44605.1 - 4.6e-52 177.0 0.0 5.9e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44605.1 - 7.9e-30 104.0 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH44605.1 - 6.4e-06 25.7 0.0 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFH44605.1 - 0.0018 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH44605.1 - 0.0036 16.7 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFH44605.1 - 0.0051 16.5 0.0 0.051 13.2 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFH44605.1 - 0.0086 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFH44605.1 - 0.03 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFH44605.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4139 PF13598.6 KFH44606.1 - 3.2e-32 112.0 1.1 2.1e-23 83.2 0.0 3.1 2 2 1 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KFH44606.1 - 1.2e-26 93.0 0.3 1.2e-26 93.0 0.3 4.6 4 1 1 5 5 5 1 N-terminal domain of unknown function (DUF4140) SUIM_assoc PF16619.5 KFH44606.1 - 4.4 7.4 12.8 0.13 12.4 1.1 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SET PF00856.28 KFH44608.1 - 1.4e-13 51.6 0.0 3.6e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFH44608.1 - 0.028 14.5 13.3 0.028 14.5 13.3 2.3 3 0 0 3 3 3 0 MYND finger Pkinase PF00069.25 KFH44609.1 - 7.1e-52 176.4 0.0 1e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44609.1 - 1.9e-23 83.1 0.0 3.9e-23 82.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFH44609.1 - 0.023 13.7 0.1 0.035 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFH44609.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 RIO1 family HlyIII PF03006.20 KFH44610.1 - 3.2e-65 220.0 11.9 3.8e-65 219.8 11.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3325 PF11804.8 KFH44610.1 - 0.05 13.8 0.5 0.05 13.8 0.5 3.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3325) DUF962 PF06127.11 KFH44610.1 - 0.062 13.4 0.8 0.35 11.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF962) DUF4271 PF14093.6 KFH44610.1 - 0.6 10.0 5.7 0.55 10.1 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) YrhK PF14145.6 KFH44610.1 - 3.3 7.7 9.3 12 5.9 0.3 3.7 3 1 1 4 4 4 0 YrhK-like protein adh_short_C2 PF13561.6 KFH44611.1 - 2.1e-58 197.7 1.3 4.6e-58 196.5 1.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH44611.1 - 1.3e-42 145.5 0.2 1.7e-42 145.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH44611.1 - 1.5e-08 34.8 0.2 4.7e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 KFH44611.1 - 0.00039 19.9 0.0 0.23 10.8 0.0 2.3 1 1 1 2 2 2 2 ThiF family DUF5448 PF17526.2 KFH44611.1 - 0.0029 17.8 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5448) DUF459 PF04311.13 KFH44611.1 - 0.021 13.8 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Peptidase_M14 PF00246.24 KFH44612.1 - 4.9e-75 253.0 0.0 5.8e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase ANAPC3 PF12895.7 KFH44613.1 - 5.7e-05 23.3 0.5 0.00012 22.2 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFH44614.1 - 0.026 14.7 0.2 0.026 14.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat EphA2_TM PF14575.6 KFH44614.1 - 0.054 14.4 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FOLN PF09289.10 KFH44614.1 - 0.073 13.3 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Adeno_E3_CR2 PF02439.15 KFH44614.1 - 0.14 12.0 0.4 0.33 10.7 0.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM95 PF15203.6 KFH44614.1 - 0.41 10.3 4.4 0.32 10.6 0.7 2.4 2 1 0 2 2 2 0 TMEM95 family DUF3669 PF12417.8 KFH44615.1 - 6.1e-19 68.0 0.1 1.1e-18 67.2 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Lipocalin_2 PF08212.12 KFH44617.1 - 6.3e-18 65.1 0.0 7.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain RSN1_7TM PF02714.15 KFH44618.1 - 3.3e-79 266.0 19.7 5.1e-79 265.4 19.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFH44618.1 - 2.7e-40 138.5 0.1 4.1e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFH44618.1 - 2.6e-36 124.8 2.3 2.6e-36 124.8 2.3 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Sugar_tr PF00083.24 KFH44619.1 - 1.3e-113 380.3 24.1 2.1e-113 379.6 24.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH44619.1 - 1.6e-23 83.2 44.5 1.2e-14 54.0 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_2 PF00535.26 KFH44620.1 - 1.2e-35 122.8 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFH44620.1 - 2.7e-12 47.1 0.0 3.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFH44620.1 - 5e-07 29.4 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KFH44620.1 - 4.8e-06 26.2 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GalKase_gal_bdg PF10509.9 KFH44621.1 - 8e-21 73.3 0.0 1.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFH44621.1 - 7.4e-14 51.7 5.2 1.2e-13 51.1 3.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFH44621.1 - 4.1e-13 49.5 0.0 1.4e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.12 KFH44621.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KFH44621.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Ldh_1_C PF02866.18 KFH44621.1 - 0.15 12.0 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Cutinase PF01083.22 KFH44622.1 - 7e-43 146.6 0.0 1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFH44622.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF3079 PF11278.8 KFH44622.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) MFS_1 PF07690.16 KFH44625.1 - 4.9e-13 48.7 38.3 4.9e-13 48.7 38.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Pre-PUA PF17832.1 KFH44626.1 - 4.8e-17 62.4 0.8 6.8e-17 61.9 0.8 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFH44626.1 - 8.3e-11 41.7 0.2 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 PUA domain p450 PF00067.22 KFH44627.1 - 1.2e-43 149.6 0.0 2.1e-43 148.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_inhib PF16857.5 KFH44630.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase inhibitor HisKA PF00512.25 KFH44630.1 - 0.21 11.6 1.4 0.33 11.0 0.3 1.8 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain HET PF06985.11 KFH44631.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Ras PF00071.22 KFH44632.1 - 1e-44 152.0 0.0 4.2e-37 127.3 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH44632.1 - 2.4e-18 66.5 0.0 2.1e-17 63.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFH44632.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RRM_1 PF00076.22 KFH44633.1 - 0.013 15.3 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3653 PF12375.8 KFH44634.1 - 0.0047 17.0 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 Phage protein DUF4451 PF14616.6 KFH44635.1 - 0.24 11.6 3.2 0.51 10.6 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) DUF515 PF04415.12 KFH44635.1 - 8.5 4.6 11.0 13 4.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Inhibitor_I78 PF11720.8 KFH44638.1 - 3.1e-07 30.3 0.0 3.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KFH44638.1 - 0.0029 18.3 0.2 0.0037 17.9 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 KFH44638.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) TMA7 PF09072.10 KFH44641.1 - 3.9e-26 91.7 20.3 4.3e-26 91.5 20.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 ADH_zinc_N PF00107.26 KFH44642.1 - 3.4e-19 69.1 0.3 3.4e-19 69.1 0.3 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH44642.1 - 4.8e-18 65.0 0.0 1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KFH44642.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KFH44642.1 - 0.077 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ANAPC4_WD40 PF12894.7 KFH44643.1 - 0.00028 21.1 0.0 0.21 11.9 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KFH44643.1 - 0.087 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin AA_permease PF00324.21 KFH44645.1 - 4.1e-52 177.4 21.5 2e-51 175.1 21.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH44645.1 - 3.9e-22 78.7 18.9 6e-22 78.1 18.9 1.2 1 0 0 1 1 1 1 Amino acid permease Na_H_Exchanger PF00999.21 KFH44646.1 - 2e-35 122.3 13.9 2.6e-35 121.9 13.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KFH44646.1 - 7.3e-05 22.8 0.8 0.00034 20.7 0.1 2.6 2 0 0 2 2 2 1 YrhC-like protein DUF3382 PF11862.8 KFH44646.1 - 0.064 13.5 0.9 0.28 11.5 0.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) AIM24 PF01987.17 KFH44648.1 - 5.1e-41 140.7 0.3 5.7e-41 140.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Velvet PF11754.8 KFH44650.1 - 2.8e-50 171.6 9.4 2.4e-33 116.2 0.0 3.3 2 2 1 3 3 3 2 Velvet factor Peptidase_C12 PF01088.21 KFH44651.1 - 1.4e-51 175.2 0.0 1.6e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Arylsulfotran_2 PF14269.6 KFH44652.1 - 1e-50 172.8 0.5 1.5e-50 172.3 0.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFH44652.1 - 1.5e-15 57.0 0.0 6.9e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) FGGY_C PF02782.16 KFH44653.1 - 2.9e-49 167.5 0.5 4.2e-49 167.0 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFH44653.1 - 1.4e-23 83.7 1.9 3e-22 79.4 0.2 3.3 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFH44653.1 - 0.0059 16.1 0.5 0.087 12.3 0.1 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MOZART1 PF12554.8 KFH44654.1 - 4.8e-25 87.1 0.7 5.6e-25 86.9 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated HTH_3 PF01381.22 KFH44654.1 - 0.13 12.3 2.1 40 4.4 0.7 3.0 3 0 0 3 3 3 0 Helix-turn-helix PMT PF02366.18 KFH44656.1 - 1.1e-88 297.0 14.4 1.1e-88 297.0 14.4 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFH44656.1 - 1.8e-64 217.0 14.0 1.8e-64 217.0 14.0 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFH44656.1 - 1.5e-36 126.0 0.6 2.4e-36 125.3 0.6 1.2 1 0 0 1 1 1 1 MIR domain Shugoshin_N PF07558.11 KFH44657.1 - 4.4e-14 52.1 6.2 9.4e-14 51.0 6.2 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KFH44657.1 - 1.3e-10 40.9 5.5 7.6e-10 38.4 5.5 2.5 1 0 0 1 1 1 1 Shugoshin C terminus Mod_r PF07200.13 KFH44657.1 - 0.019 15.1 1.7 0.053 13.6 1.7 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HA2 PF04408.23 KFH44659.1 - 2.5e-17 63.1 1.0 5.3e-17 62.1 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFH44659.1 - 4.4e-14 52.6 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFH44659.1 - 1.1e-11 45.0 0.1 3.1e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFH44659.1 - 0.00053 20.3 0.0 0.002 18.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH44659.1 - 0.0014 19.0 0.1 0.0082 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH44659.1 - 0.0044 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFH44659.1 - 0.013 16.0 0.6 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KFH44659.1 - 0.021 14.6 1.1 0.15 11.8 1.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.19 KFH44659.1 - 0.024 14.2 0.3 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KFH44659.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFH44659.1 - 0.66 9.2 2.8 0.84 8.9 0.0 2.4 2 1 1 3 3 3 0 Zeta toxin F-box PF00646.33 KFH44660.1 - 0.039 13.8 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 F-box domain CUE PF02845.16 KFH44661.1 - 2.6e-13 49.4 0.0 4.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF2880 PF11082.8 KFH44662.1 - 0.048 14.0 0.1 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) PITH PF06201.13 KFH44664.1 - 4.5e-43 147.1 0.0 5.5e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain SelP_N PF04592.14 KFH44664.1 - 8.7 5.7 10.3 12 5.3 10.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Use1 PF09753.9 KFH44665.1 - 1.6e-05 24.8 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Ribosomal_L3 PF00297.22 KFH44667.1 - 1.1e-16 60.8 2.6 3e-14 52.8 1.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 GATase_2 PF00310.21 KFH44668.1 - 5.2e-179 595.4 0.0 7.5e-179 594.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFH44668.1 - 3.4e-155 516.7 0.0 6.6e-155 515.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KFH44668.1 - 3e-108 361.6 0.0 1.4e-107 359.4 0.0 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KFH44668.1 - 2.9e-85 284.7 1.9 5.4e-85 283.8 1.9 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KFH44668.1 - 1.3e-23 83.6 0.1 8.9e-23 80.9 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KFH44668.1 - 3.9e-21 74.9 0.0 1e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KFH44668.1 - 4.3e-09 36.5 0.0 1.6e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH44668.1 - 1.2e-08 35.3 0.1 6.4e-05 23.4 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH44668.1 - 4.9e-08 32.9 1.2 0.00068 19.3 0.3 2.9 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFH44668.1 - 1.2e-06 28.1 0.1 2.6e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFH44668.1 - 1.3e-06 27.9 0.7 0.015 14.6 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH44668.1 - 1.4e-05 24.0 0.1 3.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFH44668.1 - 7.7e-05 22.2 0.2 0.00015 21.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH44668.1 - 0.0002 20.6 0.1 0.00051 19.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KFH44668.1 - 0.002 18.5 0.9 2.1 8.9 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KFH44668.1 - 0.002 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 KFH44668.1 - 0.0059 15.1 0.2 1.5 7.1 0.0 2.8 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 KFH44668.1 - 0.0071 15.7 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFH44668.1 - 0.017 14.4 0.0 0.063 12.5 0.0 1.9 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KFH44668.1 - 0.024 14.6 0.1 0.09 12.8 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 KFH44668.1 - 0.035 13.2 0.1 0.36 9.8 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein GATase_6 PF13522.6 KFH44668.1 - 0.036 14.3 0.1 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase domain F420_oxidored PF03807.17 KFH44668.1 - 0.098 13.2 0.0 1.9 9.2 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFH44668.1 - 0.12 11.8 0.1 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFH44668.1 - 0.18 11.8 0.9 41 4.2 0.1 3.1 2 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 KFH44668.1 - 0.24 11.2 1.7 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Rossmann-like domain FMN_dh PF01070.18 KFH44668.1 - 0.25 10.4 1.2 0.58 9.1 1.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GIDA PF01134.22 KFH44668.1 - 0.3 10.1 2.4 0.26 10.3 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A His_Phos_2 PF00328.22 KFH44669.1 - 1.6e-07 31.0 0.2 9.8e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3425 PF11905.8 KFH44671.1 - 1.3e-22 80.1 1.0 2.7e-22 79.1 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFH44671.1 - 0.049 13.7 14.7 0.23 11.6 14.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor SUIM_assoc PF16619.5 KFH44671.1 - 1.2 9.3 17.8 0.32 11.1 6.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4164 PF13747.6 KFH44671.1 - 1.9 8.8 8.6 0.78 10.1 5.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Rrn6 PF10214.9 KFH44672.1 - 3.3e-141 472.5 0.0 3.9e-141 472.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor E1-E2_ATPase PF00122.20 KFH44673.1 - 4.3e-49 166.5 7.8 5.8e-49 166.1 4.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFH44673.1 - 6.6e-18 65.8 0.0 1.9e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH44673.1 - 1.1e-09 37.8 0.0 2.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFH44673.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFH44673.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2012 PF09430.10 KFH44674.1 - 2.4e-19 69.6 0.0 3.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SKG6 PF08693.10 KFH44675.1 - 2.1e-07 30.2 3.1 4.1e-07 29.3 3.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 KFH44675.1 - 0.049 13.7 0.5 0.083 13.0 0.5 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KFH44675.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 KFH44675.1 - 0.26 11.1 0.1 0.43 10.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ndc1_Nup PF09531.10 KFH44675.1 - 6.4 5.3 6.4 8.3 5.0 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MARVEL PF01284.23 KFH44676.1 - 4.8e-10 39.6 10.1 6.1e-10 39.3 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain zinc_ribbon_6 PF14599.6 KFH44677.1 - 5.6e-25 87.1 0.2 5.6e-25 87.1 0.2 4.1 3 2 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 KFH44677.1 - 2e-20 73.1 19.3 2e-20 73.1 19.3 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KFH44677.1 - 8.2e-08 32.5 10.0 8.2e-08 32.5 10.0 5.5 3 2 4 7 7 7 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFH44677.1 - 8.8e-06 25.5 8.1 8.8e-06 25.5 8.1 5.1 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH44677.1 - 5.9e-05 22.8 9.3 5.9e-05 22.8 9.3 5.9 2 2 2 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFH44677.1 - 0.011 15.7 3.9 0.011 15.7 3.9 6.0 4 3 2 6 6 6 0 Prokaryotic RING finger family 1 WD40 PF00400.32 KFH44679.1 - 1.8e-06 28.5 11.9 0.18 12.8 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KFH44679.1 - 0.011 14.4 0.4 3.3 6.2 0.0 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KFH44679.1 - 0.026 14.4 0.4 6.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF2255 PF10012.9 KFH44679.1 - 0.11 12.7 0.2 5 7.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Metallophos_2 PF12850.7 KFH44680.1 - 3.9e-12 46.7 0.0 5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFH44680.1 - 0.025 15.1 0.0 0.21 12.1 0.0 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase NUC173 PF08161.12 KFH44681.1 - 1.7e-81 272.8 0.2 7.7e-78 260.8 0.1 3.9 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 KFH44681.1 - 0.0021 18.4 1.5 1.5 9.2 0.6 4.2 3 0 0 3 3 3 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KFH44681.1 - 0.024 15.2 0.3 27 5.5 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CdiI_2 PF18593.1 KFH44681.1 - 0.13 12.9 0.1 54 4.5 0.0 3.3 3 0 0 3 3 3 0 CdiI immunity protein HEAT PF02985.22 KFH44681.1 - 0.15 12.4 6.5 1.9 9.0 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat HHA PF05321.11 KFH44681.1 - 0.19 12.0 0.4 3.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Haemolysin expression modulating protein COesterase PF00135.28 KFH44682.1 - 4e-62 210.7 0.0 7.4e-62 209.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH44682.1 - 1.2e-05 25.2 2.1 2.6e-05 24.2 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Nic96 PF04097.14 KFH44683.1 - 4e-207 689.5 0.0 5.1e-207 689.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KFH44683.1 - 4.1e-06 27.5 106.2 1.5e-05 25.7 47.3 4.8 3 1 2 5 5 5 3 Nucleoporin FG repeat region DASH_Dad2 PF08654.10 KFH44684.1 - 6.5e-32 109.9 0.2 6.5e-32 109.9 0.2 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 Rogdi_lz PF10259.9 KFH44684.1 - 0.029 13.8 0.3 0.031 13.7 0.3 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein SLX9 PF15341.6 KFH44684.1 - 0.03 14.7 0.3 0.037 14.4 0.3 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 KFH44684.1 - 0.071 13.3 0.4 0.071 13.3 0.4 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KFH44684.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CTD_bind PF04818.13 KFH44685.1 - 4.8e-10 40.1 0.0 8.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KFH44685.1 - 8.8e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 KFH44686.1 - 1e-50 171.5 0.0 2e-39 134.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH44686.1 - 4.8e-29 101.0 0.0 1.6e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH44686.1 - 1.5e-11 44.1 0.0 5.2e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH44686.1 - 6.6e-06 25.8 0.0 5.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFH44686.1 - 1.1e-05 24.9 0.0 2.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFH44686.1 - 0.00012 22.2 0.0 0.00034 20.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH44686.1 - 0.0011 18.9 0.1 0.92 9.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFH44686.1 - 0.049 13.9 0.2 1.1 9.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KFH44686.1 - 0.14 12.6 0.1 0.89 10.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 KFH44686.1 - 0.19 11.4 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mito_carr PF00153.27 KFH44687.1 - 1.5e-29 101.8 4.2 2.1e-13 50.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2293 PF10056.9 KFH44688.1 - 1.3e-29 102.3 1.1 1.9e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) CHZ PF09649.10 KFH44689.1 - 3.6e-17 61.5 0.3 3.6e-17 61.5 0.3 2.4 3 1 0 3 3 3 1 Histone chaperone domain CHZ GP24_25 PF17388.2 KFH44689.1 - 0.0096 15.9 1.0 0.0096 15.9 1.0 1.8 1 1 1 2 2 2 1 Tail assembly gene products 24 & 25 SWIRM-assoc_2 PF16496.5 KFH44689.1 - 6.3 5.6 11.6 7 5.4 11.6 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ank_4 PF13637.6 KFH44690.1 - 3.1e-32 110.5 6.3 7.4e-09 36.0 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH44690.1 - 1.8e-31 108.6 5.1 7.6e-10 39.3 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH44690.1 - 2.4e-22 78.7 10.7 1.4e-05 25.3 0.2 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH44690.1 - 1.4e-21 74.2 7.0 0.00016 21.9 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.19 KFH44690.1 - 2.5e-20 73.7 16.3 4.1e-10 40.1 1.1 3.2 1 1 2 3 3 3 3 SPX domain Ank PF00023.30 KFH44690.1 - 2.5e-14 53.0 11.5 0.00033 21.0 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 KFH44690.1 - 2.2e-07 30.9 0.0 1.6e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Apc15p PF05841.11 KFH44691.1 - 1.2e-20 74.5 1.7 7e-19 68.9 1.7 2.3 1 1 0 1 1 1 1 Apc15p protein Cwf_Cwc_15 PF04889.12 KFH44691.1 - 3.5 7.3 35.0 0.13 12.0 14.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Coa1 PF08695.10 KFH44692.1 - 1.6e-41 140.7 0.0 2.1e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Cyclin PF08613.11 KFH44693.1 - 1.4e-30 106.8 0.0 2.5e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFH44693.1 - 0.00025 20.8 0.1 0.00044 20.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain VTC PF09359.10 KFH44694.1 - 1.1e-89 300.5 1.4 1.1e-89 300.5 1.4 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KFH44694.1 - 2.5e-10 40.6 2.3 2.5e-10 40.6 2.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KFH44694.1 - 2.9e-07 30.7 4.1 0.00011 22.3 0.0 4.5 3 1 2 5 5 5 2 SPX domain T3SSipB PF16535.5 KFH44694.1 - 0.038 14.5 1.1 0.038 14.5 1.1 2.5 2 1 0 2 2 2 0 Type III cell invasion protein SipB Cob_adeno_trans PF01923.18 KFH44694.1 - 0.085 13.0 0.3 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Phage_holin_3_6 PF07332.11 KFH44694.1 - 0.1 12.6 1.9 0.25 11.4 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Phasin PF05597.11 KFH44694.1 - 0.14 12.1 1.3 0.35 10.9 1.3 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TBCC_N PF16752.5 KFH44694.1 - 0.26 11.7 6.9 0.39 11.2 1.6 2.8 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain SlyX PF04102.12 KFH44694.1 - 0.89 10.2 5.6 0.35 11.5 0.3 2.8 3 0 0 3 3 3 0 SlyX MscS_porin PF12795.7 KFH44694.1 - 4.7 6.7 7.4 3.5 7.1 3.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_23 PF13476.6 KFH44694.1 - 6.4 7.2 9.8 0.9 10.0 3.4 2.2 2 0 0 2 2 2 0 AAA domain Spindle_Spc25 PF08234.12 KFH44695.1 - 7.3e-26 90.2 1.0 1.2e-25 89.5 0.2 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 KFH44695.1 - 0.057 12.8 7.9 0.077 12.3 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1730 PF08331.10 KFH44695.1 - 0.081 12.8 0.5 0.23 11.4 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) NPL PF17800.1 KFH44695.1 - 0.15 12.7 1.9 0.45 11.1 2.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin-like domain Hom_end_hint PF05203.16 KFH44695.1 - 0.34 10.8 2.8 0.51 10.3 2.8 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4554 PF15091.6 KFH44695.1 - 0.81 8.5 6.3 1.1 8.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) V_ATPase_I PF01496.19 KFH44695.1 - 1.6 6.5 7.3 2 6.2 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFH44695.1 - 1.6 7.7 7.7 2.5 7.1 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KFH44695.1 - 6.5 7.3 21.6 27 5.3 1.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Arm PF00514.23 KFH44696.1 - 2.7e-08 33.6 9.6 0.01 15.8 0.0 6.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFH44696.1 - 0.00018 21.5 9.7 0.34 11.3 0.1 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KFH44696.1 - 0.0063 17.0 13.7 0.71 10.4 0.0 6.0 6 0 0 6 6 6 2 HEAT-like repeat IFRD PF05004.13 KFH44696.1 - 0.51 9.4 0.0 0.51 9.4 0.0 3.1 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Phage_cap_E PF03864.15 KFH44697.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E Acetyltransf_1 PF00583.25 KFH44698.1 - 2.9e-16 59.8 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH44698.1 - 3e-09 37.2 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH44698.1 - 2.7e-07 30.4 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KFH44698.1 - 2.4e-06 27.5 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFH44698.1 - 6.7e-05 23.6 0.0 8.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFH44698.1 - 0.018 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KFH44698.1 - 0.08 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family MatE PF01554.18 KFH44699.1 - 8.1e-06 25.6 15.8 0.002 17.8 3.4 3.2 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFH44699.1 - 0.0006 19.9 0.2 0.0006 19.9 0.2 4.3 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TIG PF01833.24 KFH44700.1 - 9.2e-12 44.9 0.8 2.5e-11 43.5 0.8 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.6 KFH44700.1 - 4.1e-11 42.9 2.1 2.4e-09 37.3 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH44700.1 - 6.4e-08 33.1 0.1 1.4e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFH44700.1 - 6.7e-08 32.6 3.4 0.004 17.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFH44700.1 - 6e-07 29.3 0.4 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFH44700.1 - 1.9e-05 25.1 0.7 0.00064 20.2 0.3 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) TadE PF07811.12 KFH44700.1 - 0.064 13.5 0.9 0.12 12.6 0.9 1.4 1 0 0 1 1 1 0 TadE-like protein Cys_Met_Meta_PP PF01053.20 KFH44701.1 - 1.5e-151 504.3 0.0 1.7e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFH44701.1 - 8.6e-11 41.7 0.8 1.3e-10 41.1 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KFH44701.1 - 2.1e-09 37.1 0.0 4.5e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFH44701.1 - 1.2e-07 31.1 0.4 2e-07 30.3 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFH44701.1 - 6.1e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KFH44701.1 - 0.00015 20.4 0.2 0.0002 20.0 0.2 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KFH44701.1 - 0.038 12.7 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS AMP-binding PF00501.28 KFH44702.1 - 1.9e-82 277.1 0.0 2.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NIT PF08376.10 KFH44702.1 - 0.09 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing Citrate_synt PF00285.21 KFH44704.1 - 1.4e-100 336.9 0.0 1.8e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KFH44704.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Smr PF01713.21 KFH44704.1 - 0.03 14.7 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Smr domain Choline_transpo PF04515.12 KFH44705.1 - 1.6e-31 109.7 18.4 1.6e-31 109.7 18.4 2.7 2 2 0 2 2 2 1 Plasma-membrane choline transporter Rad52_Rad22 PF04098.15 KFH44706.1 - 3.1e-58 196.0 0.0 4.5e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DSBA PF01323.20 KFH44708.1 - 8.6e-15 55.0 0.8 6.3e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Cyt-b5 PF00173.28 KFH44709.1 - 1.9e-11 43.9 0.1 2.3e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UQ_con PF00179.26 KFH44710.1 - 3.7e-47 159.5 0.0 4.1e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH44710.1 - 0.00075 19.2 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFH44710.1 - 0.037 14.3 0.8 0.049 13.9 0.8 1.5 1 1 0 1 1 1 0 RWD domain Ribosomal_L44 PF00935.19 KFH44711.1 - 2.9e-36 123.8 14.0 4.4e-36 123.2 14.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 GFA PF04828.14 KFH44712.1 - 8.7e-25 86.9 0.0 1.3e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2 PF00096.26 KFH44713.1 - 1.9e-07 31.1 21.1 0.0011 19.3 4.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH44713.1 - 5e-07 30.0 25.4 0.00034 21.2 3.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH44713.1 - 0.0013 18.6 1.5 0.0013 18.6 1.5 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH44713.1 - 4.2 7.8 15.0 1.5 9.2 4.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH44713.1 - 9.9 6.7 17.2 1.7 9.2 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Porin_3 PF01459.22 KFH44714.1 - 2.4e-65 220.7 6.2 4e-56 190.4 4.2 2.1 2 0 0 2 2 2 2 Eukaryotic porin DivIC PF04977.15 KFH44716.1 - 0.0025 17.5 0.5 0.0058 16.4 0.5 1.6 1 0 0 1 1 1 1 Septum formation initiator TPR_2 PF07719.17 KFH44716.1 - 0.05 13.7 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 KFH44717.1 - 0.0067 17.2 14.7 0.14 13.0 0.3 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH44717.1 - 5.4 7.7 15.4 16 6.2 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type AIM24 PF01987.17 KFH44718.1 - 1e-46 159.3 0.1 1.3e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ten1 PF12658.7 KFH44719.1 - 2.3e-30 105.0 0.0 2.6e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KFH44719.1 - 4.7e-05 23.1 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit RMI2 PF16100.5 KFH44719.1 - 0.081 12.7 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 DUF3433 PF11915.8 KFH44720.1 - 3.5e-37 126.8 17.9 1.2e-20 73.7 2.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF2569 PF10754.9 KFH44720.1 - 0.053 14.0 0.1 0.19 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) AA_permease_2 PF13520.6 KFH44720.1 - 0.86 8.4 6.3 0.28 10.0 0.5 2.8 4 0 0 4 4 4 0 Amino acid permease MarR PF01047.22 KFH44722.1 - 0.084 12.8 2.2 0.13 12.2 2.2 1.3 1 0 0 1 1 1 0 MarR family Ureidogly_lyase PF04115.12 KFH44723.1 - 7.1e-57 192.2 0.0 8.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF4820 PF16091.5 KFH44726.1 - 1.1 8.6 4.0 1.6 8.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ORMDL PF04061.14 KFH44727.1 - 1.4e-58 196.5 4.7 1.7e-58 196.2 4.7 1.1 1 0 0 1 1 1 1 ORMDL family CDH-cyt PF16010.5 KFH44730.1 - 1.2e-19 70.7 0.0 1.9e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KFH44730.1 - 1e-08 35.4 10.9 1e-08 35.4 10.9 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KFH44730.1 - 0.0002 21.1 4.4 0.0002 21.1 4.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF2157 PF09925.9 KFH44730.1 - 0.00085 19.1 6.5 0.0023 17.7 1.7 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF4079 PF13301.6 KFH44730.1 - 0.0068 16.6 9.6 0.15 12.2 5.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) EphA2_TM PF14575.6 KFH44730.1 - 0.18 12.7 0.1 5.1 8.0 0.0 3.1 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3382 PF11862.8 KFH44730.1 - 0.31 11.3 5.1 2.3 8.5 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) DUF2070 PF09843.9 KFH44730.1 - 0.61 8.3 7.9 0.9 7.8 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 KFH44730.1 - 1.1 9.3 6.4 1.1 9.3 1.3 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Deltameth_res PF16020.5 KFH44730.1 - 1.1 9.1 4.1 21 5.1 0.3 2.9 2 0 0 2 2 2 0 Deltamethrin resistance DoxX_3 PF13781.6 KFH44730.1 - 8.2 7.1 9.5 1 10.0 1.0 2.6 2 0 0 2 2 2 0 DoxX-like family MFS_1 PF07690.16 KFH44731.1 - 8.2e-32 110.5 57.9 2.1e-28 99.3 37.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH44731.1 - 1.1e-14 54.2 29.4 8e-14 51.3 29.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter zf-PHD-like PF15446.6 KFH44732.1 - 4.4e-71 237.9 11.0 9.1e-71 236.9 11.0 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KFH44732.1 - 1.1e-48 165.7 0.0 3.3e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH44732.1 - 1.4e-19 70.5 0.0 1.3e-18 67.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFH44732.1 - 1.7e-08 34.0 0.8 3.6e-08 32.9 0.8 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KFH44732.1 - 1.2e-07 31.6 0.7 9.2e-06 25.5 0.2 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFH44732.1 - 6.8e-07 29.4 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KFH44732.1 - 3e-06 27.0 8.8 3e-06 27.0 8.8 3.0 3 0 0 3 3 3 2 PHD-finger DEAD PF00270.29 KFH44732.1 - 0.0035 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KFH44732.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PHD_2 PF13831.6 KFH44732.1 - 0.54 9.9 10.8 0.042 13.4 4.9 2.2 2 0 0 2 2 2 0 PHD-finger Formyl_trans_N PF00551.19 KFH44733.1 - 4.8e-16 59.0 0.0 7.1e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Kinesin PF00225.23 KFH44735.1 - 9.1e-112 373.3 0.1 9.1e-112 373.3 0.1 1.6 2 0 0 2 2 1 1 Kinesin motor domain DUF3694 PF12473.8 KFH44735.1 - 1.6e-49 168.5 0.6 3.7e-49 167.3 0.0 2.0 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KFH44735.1 - 4.7e-35 121.4 19.1 4.8e-31 108.3 0.1 4.1 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KFH44735.1 - 7.6e-24 84.3 1.3 1.1e-23 83.8 0.1 2.0 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 KFH44735.1 - 2e-06 28.2 0.3 8.2e-06 26.2 0.3 2.2 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KFH44735.1 - 0.00051 20.5 0.0 0.49 10.9 0.0 2.8 2 0 0 2 2 2 2 PH domain Yop-YscD_cpl PF16697.5 KFH44735.1 - 0.046 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Trypan_PARP PF05887.11 KFH44735.1 - 2.9 7.9 13.8 7.6 6.5 13.8 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) V_ATPase_I PF01496.19 KFH44735.1 - 3.4 5.5 9.6 3.4 5.5 7.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KFH44735.1 - 4.3 6.8 14.5 5.8 6.4 11.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phage_Nu1 PF07471.12 KFH44735.1 - 8.1 6.2 9.0 20 4.9 9.0 1.6 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 LIM PF00412.22 KFH44736.1 - 1.9e-20 72.9 21.0 6.6e-11 42.3 3.3 3.0 3 0 0 3 3 3 2 LIM domain zf_C2HC_14 PF18574.1 KFH44736.1 - 0.88 9.4 3.5 0.7 9.7 0.8 2.2 2 0 0 2 2 2 0 C2HC Zing finger domain Cyt-b5 PF00173.28 KFH44738.1 - 8.4e-22 77.1 0.3 9.4e-22 77.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 KFH44738.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H MRC1 PF09444.10 KFH44739.1 - 2.6e-42 144.8 21.4 2.6e-42 144.8 21.4 9.2 7 3 2 9 9 9 1 MRC1-like domain Cut8 PF08559.10 KFH44740.1 - 9.4e-76 254.6 0.0 1.2e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein ABC1 PF03109.16 KFH44741.1 - 1.7e-32 112.0 0.1 3.2e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 ABC1 family UCR_Fe-S_N PF10399.9 KFH44741.1 - 0.0036 16.6 1.1 0.01 15.2 1.1 1.7 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal RRM_1 PF00076.22 KFH44742.1 - 9.8e-19 67.0 0.4 3.1e-11 42.9 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFH44742.1 - 0.0081 16.2 2.3 0.015 15.4 0.3 2.5 2 1 1 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KFH44742.1 - 0.011 15.8 0.1 0.33 11.1 0.1 2.4 2 1 0 2 2 2 0 RNA recognition motif Es2 PF09751.9 KFH44742.1 - 0.026 14.3 2.4 3.1 7.4 0.2 2.3 1 1 0 2 2 2 0 Nuclear protein Es2 RRM_Rrp7 PF17799.1 KFH44742.1 - 0.033 14.0 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KFH44742.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TPR_12 PF13424.6 KFH44743.1 - 5.2e-05 23.5 0.3 0.43 10.9 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH44743.1 - 0.00039 20.3 4.5 0.0077 16.3 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH44743.1 - 0.00053 19.7 0.2 0.48 10.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TerY_C PF15616.6 KFH44743.1 - 0.018 15.2 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Pex19 PF04614.12 KFH44744.1 - 8.9e-77 258.1 9.0 8.9e-77 258.1 9.0 2.0 1 1 1 2 2 2 1 Pex19 protein family FliE PF02049.18 KFH44744.1 - 5.7 7.2 6.6 8.3 6.6 0.7 3.5 2 2 1 3 3 3 0 Flagellar hook-basal body complex protein FliE FKBP_N PF01346.18 KFH44744.1 - 7.5 7.6 8.5 3.7 8.6 0.4 3.4 1 1 3 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_M48 PF01435.18 KFH44746.1 - 1e-36 126.6 0.0 3.2e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Asn_synthase PF00733.21 KFH44748.1 - 2.4e-91 307.1 0.2 7e-88 295.7 0.2 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KFH44748.1 - 5.3e-36 123.2 0.0 8.6e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFH44748.1 - 5.1e-27 94.7 0.0 9.7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFH44748.1 - 1.2e-08 34.7 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFH44748.1 - 0.00056 19.1 0.0 0.0013 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Torus PF16131.5 KFH44749.1 - 0.2 12.4 2.6 0.91 10.3 0.3 2.2 2 0 0 2 2 2 0 Torus domain HCV_NS5a_C PF12941.7 KFH44750.1 - 0.18 11.6 1.6 0.22 11.4 1.6 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region PXA PF02194.15 KFH44751.1 - 2.6e-31 109.0 0.0 5.2e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KFH44751.1 - 1.3e-22 80.5 0.1 4.2e-22 78.8 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFH44751.1 - 5.3e-07 29.6 0.0 2.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 PX domain DLEU7 PF15760.5 KFH44751.1 - 0.1 12.1 2.9 0.56 9.7 0.0 2.7 2 0 0 2 2 2 0 Leukemia-associated protein 7 Coatomer_E PF04733.14 KFH44753.1 - 2.1e-63 214.5 1.8 2.4e-63 214.3 1.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFH44753.1 - 1.9e-10 41.1 13.7 2.6e-05 24.6 0.9 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH44753.1 - 3.6e-06 27.2 6.4 0.0031 17.8 0.3 4.7 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFH44753.1 - 1.1e-05 25.7 1.2 0.031 14.9 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFH44753.1 - 4e-05 23.0 1.7 0.0074 15.5 0.2 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH44753.1 - 4.6e-05 23.5 0.6 0.56 10.5 0.2 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFH44753.1 - 5.2e-05 22.9 0.4 0.024 14.5 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH44753.1 - 9.4e-05 22.9 16.6 0.0054 17.5 0.9 5.6 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH44753.1 - 0.00017 21.6 0.9 0.19 12.0 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH44753.1 - 0.002 18.7 11.9 0.061 14.0 0.4 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFH44753.1 - 0.0028 17.7 0.3 0.0028 17.7 0.3 5.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFH44753.1 - 0.0094 16.5 19.4 0.12 13.1 0.3 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH44753.1 - 0.023 14.4 0.8 0.023 14.4 0.8 3.5 5 0 0 5 5 5 0 TPR repeat SNAP PF14938.6 KFH44753.1 - 0.028 13.9 2.8 0.37 10.2 0.1 2.4 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 KFH44753.1 - 0.031 13.2 1.2 1.4 7.8 0.1 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 KFH44753.1 - 0.033 14.6 0.0 25 5.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFH44753.1 - 0.067 13.4 1.8 0.38 10.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH44753.1 - 0.72 10.0 7.5 9.3 6.5 0.1 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat YlqD PF11068.8 KFH44754.1 - 0.58 10.5 5.4 1.1 9.6 5.4 1.5 1 1 0 1 1 1 0 YlqD protein MBF1 PF08523.10 KFH44755.1 - 8.4e-28 96.6 0.9 1.5e-27 95.9 0.9 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KFH44755.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KFH44755.1 - 0.038 14.3 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Med1 PF10744.9 KFH44756.1 - 1.2e-103 347.4 0.0 2e-103 346.6 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF952 PF06108.12 KFH44757.1 - 1.4e-21 76.3 0.0 2e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) TRP PF06011.12 KFH44758.1 - 3.4e-158 526.8 30.7 4.2e-158 526.6 30.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFH44758.1 - 3.1e-39 134.5 1.1 5.1e-39 133.8 1.1 1.4 1 0 0 1 1 1 1 ML-like domain DUF4992 PF16383.5 KFH44758.1 - 0.0096 15.5 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function VirB3 PF05101.13 KFH44758.1 - 0.1 12.9 6.5 5.7 7.3 0.8 3.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein TcpE PF12648.7 KFH44758.1 - 6.1 7.4 19.8 0.44 11.1 2.0 3.5 3 1 0 3 3 3 0 TcpE family SUR7 PF06687.12 KFH44759.1 - 1.5e-15 57.4 3.4 4e-15 56.0 3.3 1.6 1 1 1 2 2 2 1 SUR7/PalI family CcmD PF04995.14 KFH44759.1 - 0.037 14.1 0.3 0.037 14.1 0.3 3.2 4 1 0 4 4 4 0 Heme exporter protein D (CcmD) YdaT_toxin PF06254.11 KFH44759.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative bacterial toxin ydaT Adeno_E3_CR2 PF02439.15 KFH44759.1 - 0.35 10.7 0.0 0.35 10.7 0.0 3.5 3 1 0 3 3 3 0 Adenovirus E3 region protein CR2 DUF3087 PF11286.8 KFH44759.1 - 2.1 7.8 3.8 3.8 6.9 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) YccF PF03733.13 KFH44759.1 - 3.6 8.4 0.0 3.6 8.4 0.0 3.4 3 1 0 3 3 3 0 Inner membrane component domain Claudin_3 PF06653.11 KFH44759.1 - 7.7 6.4 11.2 2 8.4 4.5 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like PC4 PF02229.16 KFH44760.1 - 2.5e-21 75.1 3.3 2.2e-16 59.2 0.6 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.6 KFH44760.1 - 0.033 14.4 0.0 0.033 14.4 0.0 1.8 2 0 0 2 2 2 0 YqfQ-like protein DUF5039 PF16442.5 KFH44760.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) Stm1_N PF09598.10 KFH44760.1 - 8.1 7.4 11.2 2.1 9.3 3.0 2.4 2 0 0 2 2 2 0 Stm1 XRCC4 PF06632.12 KFH44762.1 - 2.7 6.8 6.5 6.1 5.6 6.5 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SUR7 PF06687.12 KFH44763.1 - 2.3e-28 99.3 13.6 2.8e-28 99.0 13.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Peptidase_M1 PF01433.20 KFH44766.1 - 9.4e-43 146.3 2.3 1.4e-42 145.7 2.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFH44766.1 - 3.4e-40 136.6 0.0 6.7e-40 135.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFH44766.1 - 2.6e-29 102.8 0.0 4.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KFH44766.1 - 0.00028 20.6 0.8 0.0087 15.8 0.7 2.8 2 1 0 2 2 2 1 Peptidase MA superfamily TbpB_B_D PF01298.18 KFH44766.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Peptidase_M61 PF05299.12 KFH44766.1 - 1.3 9.4 3.6 11 6.4 2.5 2.7 2 1 0 2 2 2 0 M61 glycyl aminopeptidase DnaJ PF00226.31 KFH44768.1 - 3.7e-15 55.8 0.1 5.7e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SpoU_methylase PF00588.19 KFH44769.1 - 4e-25 88.6 0.0 6.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFH44769.1 - 3.2e-11 43.4 0.0 5.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF3405 PF11885.8 KFH44770.1 - 1e-194 648.0 0.7 1.3e-194 647.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Uds1 PF15456.6 KFH44771.1 - 2e-22 79.8 7.2 4.1e-21 75.5 3.1 3.6 4 0 0 4 4 4 2 Up-regulated During Septation NAD_binding_5 PF07994.12 KFH44772.1 - 6e-146 485.9 0.2 8.1e-146 485.5 0.2 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFH44772.1 - 1.2e-45 154.2 0.8 2.9e-45 153.0 0.8 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FERM_N PF09379.10 KFH44773.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain Sigma70_r4 PF04545.16 KFH44773.1 - 0.16 11.5 0.0 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 Sec6 PF06046.13 KFH44774.1 - 1.6e-168 561.7 2.3 2.1e-168 561.3 2.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KFH44774.1 - 0.0021 17.1 2.5 0.0049 15.9 0.3 2.6 2 1 1 3 3 3 1 Vps53-like, N-terminal OmdA PF13376.6 KFH44774.1 - 0.0062 16.5 3.4 0.07 13.2 0.0 3.2 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated DENN PF02141.21 KFH44775.1 - 4.8e-41 140.8 0.1 8.8e-41 139.9 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFH44775.1 - 2.8e-05 24.8 0.0 9.6e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 uDENN domain PCRF PF03462.18 KFH44775.1 - 5.7 6.8 14.5 0.8 9.5 6.7 2.8 2 1 1 3 3 3 0 PCRF domain DUF2570 PF10828.8 KFH44775.1 - 7.9 6.3 15.0 2.5 8.0 8.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CFEM PF05730.11 KFH44776.1 - 5.9e-13 48.7 5.0 1.1e-12 47.8 5.0 1.5 1 0 0 1 1 1 1 CFEM domain CytochromB561_N PF09786.9 KFH44776.1 - 0.46 9.4 8.3 0.51 9.3 8.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SAPS PF04499.15 KFH44776.1 - 3.5 6.3 4.8 3.7 6.2 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KFH44776.1 - 7.3 4.6 9.7 8.9 4.3 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 KFH44776.1 - 8.4 6.2 17.7 10 5.9 17.7 1.1 1 0 0 1 1 1 0 SPX domain DUF2264 PF10022.9 KFH44777.1 - 7.7e-124 413.3 0.4 1e-123 413.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Peptidase_C36 PF05415.11 KFH44777.1 - 0.03 14.5 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Perilipin PF03036.16 KFH44778.1 - 0.00083 18.5 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Perilipin family Vault_2 PF17794.1 KFH44778.1 - 0.07 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Major Vault Protein repeat domain DUF4600 PF15372.6 KFH44779.1 - 0.07 13.6 6.3 0.079 13.4 4.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Golgin_A5 PF09787.9 KFH44779.1 - 0.089 12.2 12.9 0.16 11.4 12.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KFH44779.1 - 0.33 10.0 5.6 5.6 6.0 5.7 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 KFH44779.1 - 0.35 10.5 9.0 0.27 10.9 7.0 1.8 1 1 1 2 2 2 0 GrpE AAA_23 PF13476.6 KFH44779.1 - 0.45 11.0 4.8 0.79 10.2 4.8 1.4 1 0 0 1 1 1 0 AAA domain Goodbye PF17109.5 KFH44779.1 - 0.61 10.5 2.6 1.3 9.5 0.9 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain zf-C4H2 PF10146.9 KFH44779.1 - 0.81 10.0 14.9 0.45 10.8 9.0 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein AATF-Che1 PF13339.6 KFH44779.1 - 1.6 9.4 5.9 2.3 8.9 4.3 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Laminin_II PF06009.12 KFH44779.1 - 1.7 8.6 12.0 11 6.1 8.3 3.3 2 1 1 3 3 3 0 Laminin Domain II SHE3 PF17078.5 KFH44779.1 - 6 6.5 11.1 1.8 8.2 5.5 2.5 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Fungal_trans PF04082.18 KFH44780.1 - 1.9e-06 27.2 0.0 3.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44780.1 - 7.2e-05 22.8 12.5 0.00012 22.1 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 KFH44780.1 - 2.6 8.5 11.5 2.9 8.3 1.6 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GATase PF00117.28 KFH44781.1 - 1.7e-12 47.5 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFH44781.1 - 0.00022 21.1 2.6 0.0034 17.2 2.6 2.5 1 1 0 1 1 1 1 Peptidase C26 VirJ PF06057.11 KFH44781.1 - 0.05 13.5 0.1 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Het-C PF07217.11 KFH44782.1 - 6e-275 913.1 0.0 7.5e-275 912.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C His_Phos_1 PF00300.22 KFH44784.1 - 2.1e-29 102.6 0.0 7e-29 100.9 0.0 1.9 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KFH44784.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Paf1 PF03985.13 KFH44784.1 - 0.63 9.0 16.8 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Paf1 VWA_2 PF13519.6 KFH44785.1 - 1.2e-06 29.1 0.0 6.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFH44785.1 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4013 PF13197.6 KFH44786.1 - 0.00028 20.8 0.6 0.00041 20.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF3021 PF11457.8 KFH44786.1 - 0.058 13.7 1.7 0.2 12.0 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) EamA PF00892.20 KFH44787.1 - 1.3e-19 70.8 28.7 1.8e-10 41.2 7.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 KFH44788.1 - 1.1e-44 150.1 1.1 7.8e-21 73.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFH44788.1 - 7.2e-23 81.5 0.1 2e-22 80.1 0.1 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFH44788.1 - 5.4e-05 23.0 0.0 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFH44788.1 - 0.00024 21.0 0.0 0.27 11.3 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFH44788.1 - 0.0029 17.8 0.2 0.15 12.3 0.2 3.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KFH44788.1 - 0.0068 16.4 1.0 0.27 11.3 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KFH44788.1 - 0.0087 16.2 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KFH44788.1 - 0.096 12.3 0.0 0.41 10.3 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 KFH44789.1 - 1.4e-17 63.8 0.3 2.8e-17 62.9 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFH44789.1 - 0.012 16.2 0.3 0.025 15.2 0.3 1.5 1 0 0 1 1 1 0 HMG-box domain DUF1289 PF06945.13 KFH44789.1 - 0.84 9.5 4.0 0.54 10.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Glyco_hydro_2_C PF02836.17 KFH44790.1 - 2.9e-96 322.2 0.0 4e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFH44790.1 - 2e-62 211.0 0.0 3.6e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFH44790.1 - 5.8e-50 169.5 3.4 1.1e-49 168.6 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFH44790.1 - 6.3e-25 87.5 0.2 1.7e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFH44790.1 - 1.5e-09 38.5 0.0 3.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.14 KFH44790.1 - 2.9e-05 23.5 0.1 0.00028 20.2 0.0 2.2 2 1 0 3 3 3 1 Glucanosyltransferase Tcp11 PF05794.13 KFH44791.1 - 2e-107 360.0 0.1 2.9e-107 359.5 0.1 1.2 1 0 0 1 1 1 1 T-complex protein 11 Myf5 PF12232.8 KFH44791.1 - 0.011 16.5 0.8 0.042 14.6 0.8 2.0 1 0 0 1 1 1 0 Myogenic determination factor 5 TatD_DNase PF01026.21 KFH44792.1 - 5.1e-46 157.1 0.0 1.1e-45 156.0 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Ecl1 PF12855.7 KFH44793.1 - 4.9e-16 60.4 19.0 5.7e-16 60.2 19.0 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 KFH44793.1 - 2.3 8.3 6.2 0.27 11.2 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PLATZ PF04640.14 KFH44793.1 - 3.1 8.5 7.3 0.22 12.1 1.5 2.1 3 0 0 3 3 3 0 PLATZ transcription factor DUF1242 PF06842.12 KFH44794.1 - 4.4e-16 58.4 0.1 7.3e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Aminotran_1_2 PF00155.21 KFH44795.1 - 4e-32 111.8 0.0 5.1e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1330 PF07045.11 KFH44796.1 - 1.1e-21 77.0 0.0 1.3e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) YCII PF03795.14 KFH44796.1 - 0.076 13.4 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 YCII-related domain GMC_oxred_N PF00732.19 KFH44797.1 - 2.2e-40 138.9 0.3 3.9e-40 138.1 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH44797.1 - 2.7e-28 99.3 2.4 9.2e-27 94.3 0.3 2.5 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFH44797.1 - 2.7e-05 23.5 4.2 4.7e-05 22.6 4.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH44797.1 - 0.00033 20.0 2.2 0.0008 18.7 2.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH44797.1 - 0.00064 19.1 0.4 0.00095 18.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFH44797.1 - 0.0013 18.1 0.8 0.0035 16.6 0.3 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFH44797.1 - 0.03 14.6 2.3 0.03 14.6 2.3 2.8 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFH44797.1 - 0.035 13.5 3.8 0.05 12.9 3.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH44797.1 - 0.072 11.8 1.4 0.11 11.2 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 KFH44797.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KFH44797.1 - 0.25 10.4 1.8 0.66 9.0 1.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 KFH44797.1 - 0.3 10.6 5.7 1.6 8.2 3.4 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NMT1 PF09084.11 KFH44798.1 - 5.2e-78 261.9 0.0 6.2e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KFH44798.1 - 8e-06 25.7 0.1 0.061 13.0 0.0 3.0 3 0 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.7 KFH44798.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 KFH44798.1 - 0.16 11.1 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain SRP19 PF01922.17 KFH44799.1 - 5.1e-32 110.7 0.0 9e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein AAA PF00004.29 KFH44801.1 - 5.1e-37 127.3 0.0 6.7e-12 46.0 0.0 4.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH44801.1 - 9.2e-12 45.4 10.2 0.049 13.9 1.9 7.2 5 2 0 5 5 5 3 AAA domain AAA_5 PF07728.14 KFH44801.1 - 1.8e-10 40.9 0.3 0.022 14.8 0.0 4.0 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFH44801.1 - 2.1e-10 40.7 0.2 0.061 13.0 0.0 4.0 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.6 KFH44801.1 - 8e-09 36.1 5.3 0.014 15.8 0.1 4.3 4 1 0 4 4 3 2 AAA ATPase domain AAA_lid_6 PF17866.1 KFH44801.1 - 2.6e-08 33.9 0.5 2.8e-07 30.6 0.7 2.7 2 0 0 2 2 1 1 AAA lid domain RuvB_N PF05496.12 KFH44801.1 - 1.3e-07 31.5 0.0 0.079 12.7 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KFH44801.1 - 2.1e-07 30.5 0.1 3 7.2 0.0 6.2 6 1 1 7 7 7 1 Bacterial TniB protein Mg_chelatase PF01078.21 KFH44801.1 - 4.5e-07 29.4 0.1 0.26 10.6 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFH44801.1 - 9.9e-07 29.0 1.5 0.74 10.0 0.0 4.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KFH44801.1 - 2.3e-06 27.9 0.0 0.73 10.3 0.0 3.7 3 0 0 3 3 3 2 RNA helicase AAA_19 PF13245.6 KFH44801.1 - 3.6e-06 27.4 0.2 1.7 9.0 0.1 3.9 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFH44801.1 - 4.6e-06 26.5 0.0 0.73 9.5 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFH44801.1 - 8.2e-05 23.2 6.6 1.5 9.4 0.1 4.1 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 KFH44801.1 - 0.0001 21.9 0.6 2.8 7.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_24 PF13479.6 KFH44801.1 - 0.00011 22.0 7.9 1.1 8.9 0.4 3.9 2 1 1 3 3 3 3 AAA domain NTPase_1 PF03266.15 KFH44801.1 - 0.00019 21.4 1.3 3.1 7.7 0.0 3.8 3 0 0 3 3 3 1 NTPase Sigma54_activat PF00158.26 KFH44801.1 - 0.00028 20.6 0.7 9.9 5.8 0.0 4.4 4 1 0 4 4 4 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFH44801.1 - 0.00045 20.1 7.8 0.41 10.4 0.0 4.5 4 0 0 4 4 4 1 AAA domain Torsin PF06309.11 KFH44801.1 - 0.00052 20.1 0.0 3.8 7.6 0.0 3.8 3 0 0 3 3 3 1 Torsin Viral_helicase1 PF01443.18 KFH44801.1 - 0.0013 18.6 0.9 0.29 10.8 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KFH44801.1 - 0.0039 17.7 2.1 13 6.3 0.1 3.8 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 KFH44801.1 - 0.0047 16.6 0.1 7.9 6.3 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFH44801.1 - 0.0066 16.1 2.1 22 4.6 0.1 4.8 4 1 1 5 5 5 0 AAA domain ADK PF00406.22 KFH44801.1 - 0.016 15.3 3.2 10 6.2 0.1 4.1 4 0 0 4 4 3 0 Adenylate kinase NB-ARC PF00931.22 KFH44801.1 - 0.022 13.9 0.0 17 4.5 0.0 3.8 3 0 0 3 3 3 0 NB-ARC domain BaffR-Tall_bind PF09256.10 KFH44801.1 - 0.043 13.6 0.7 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding AAA_17 PF13207.6 KFH44801.1 - 0.066 13.6 16.9 0.54 10.7 0.0 4.4 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.22 KFH44801.1 - 0.11 12.1 3.0 2.1 8.0 0.0 3.5 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain ResIII PF04851.15 KFH44801.1 - 0.13 12.2 0.0 92 3.0 0.0 4.5 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KFH44801.1 - 0.2 11.7 0.1 23 5.0 0.1 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFH44801.1 - 0.3 11.3 13.2 5.4 7.2 0.0 4.4 5 0 0 5 5 3 0 AAA domain ATPase PF06745.13 KFH44801.1 - 0.43 9.9 2.4 23 4.2 0.0 3.3 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.9 KFH44801.1 - 0.46 9.7 6.3 58 2.8 0.0 4.6 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KFH44801.1 - 0.58 9.1 9.9 2.8 6.8 0.0 4.1 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KFH44801.1 - 0.79 9.1 6.3 17 4.8 0.0 4.1 4 1 0 4 4 4 0 Chromatin associated protein KTI12 bZIP_2 PF07716.15 KFH44803.1 - 7.6e-13 48.3 10.5 7.6e-13 48.3 10.5 1.7 2 0 0 2 2 2 1 Basic region leucine zipper ATG16 PF08614.11 KFH44803.1 - 0.0014 18.9 8.8 0.0018 18.5 8.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KFH44803.1 - 0.002 18.2 14.8 0.0089 16.1 10.3 1.8 1 1 1 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 KFH44803.1 - 0.011 16.1 0.4 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KFH44803.1 - 0.012 15.4 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CREPT PF16566.5 KFH44803.1 - 0.063 13.5 2.0 0.099 12.8 2.0 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2357 PF09823.9 KFH44803.1 - 0.25 10.6 4.1 0.37 10.0 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) XhlA PF10779.9 KFH44803.1 - 0.35 11.1 2.2 0.78 10.0 2.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 KFH44803.1 - 0.38 11.0 7.6 0.58 10.4 7.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 KFH44803.1 - 2.4 8.4 7.6 2.4 8.4 6.4 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 KFH44803.1 - 3.4 8.3 5.0 5 7.8 2.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA OMPdecase PF00215.24 KFH44804.1 - 6.3e-111 369.4 0.0 7.4e-111 369.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf_CCCH_4 PF18345.1 KFH44805.1 - 0.0002 21.3 2.4 0.0052 16.8 0.4 2.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KFH44805.1 - 0.0017 18.2 3.2 0.0017 18.2 3.2 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFH44805.1 - 0.0018 18.9 0.1 0.0018 18.9 0.1 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 KFH44805.1 - 6.6 6.7 11.3 3.1 7.7 2.6 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Pirin PF02678.16 KFH44806.1 - 1.4e-29 102.2 3.7 1.5e-29 102.1 0.0 2.6 3 0 0 3 3 3 1 Pirin Pirin_C PF05726.13 KFH44806.1 - 2.6e-25 88.8 0.0 8e-24 84.0 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KFH44806.1 - 7.7e-06 25.5 2.7 0.00011 21.8 0.4 3.5 3 0 0 3 3 3 2 Cupin domain TraU PF06834.11 KFH44806.1 - 0.021 14.1 0.5 0.033 13.5 0.5 1.2 1 0 0 1 1 1 0 TraU protein SUIM_assoc PF16619.5 KFH44806.1 - 0.029 14.4 5.2 0.078 13.1 5.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cupin_3 PF05899.12 KFH44806.1 - 0.032 13.9 0.9 1.8 8.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF861) SelP_N PF04592.14 KFH44806.1 - 0.16 11.4 9.7 0.26 10.7 9.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM176 PF14851.6 KFH44806.1 - 0.23 11.1 0.8 0.36 10.5 0.8 1.2 1 0 0 1 1 1 0 FAM176 family PP2C PF00481.21 KFH44807.1 - 1.7e-38 132.7 0.0 2.3e-32 112.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFH44807.1 - 0.00023 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C TRIQK PF15168.6 KFH44807.1 - 0.17 11.8 0.0 25 4.9 0.0 2.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family CDP-OH_P_transf PF01066.21 KFH44808.1 - 5.2e-12 46.4 0.2 5.2e-12 46.4 0.2 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HATPase_c PF02518.26 KFH44809.1 - 2.9e-23 82.5 0.3 6.8e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH44809.1 - 1.5e-21 76.7 0.0 3.3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 KFH44809.1 - 4.3e-21 75.0 0.9 2e-11 44.0 0.3 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KFH44809.1 - 6.1e-20 71.0 0.1 1.8e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KFH44809.1 - 5.8e-08 32.9 0.0 0.012 15.9 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KFH44809.1 - 6.6e-07 29.6 0.0 2.9e-05 24.3 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFH44809.1 - 2.9e-05 24.0 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KFH44809.1 - 0.00073 19.5 0.0 0.044 13.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain FA_hydroxylase PF04116.13 KFH44810.1 - 2.2e-23 83.0 9.4 2.2e-23 83.0 9.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1168 PF06658.12 KFH44811.1 - 4.7e-39 133.3 13.7 7.2e-39 132.7 13.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) UreF PF01730.16 KFH44811.1 - 0.22 12.1 0.7 0.38 11.4 0.7 1.3 1 0 0 1 1 1 0 UreF DUF4407 PF14362.6 KFH44811.1 - 1.3 8.3 3.1 1.4 8.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) D-ser_dehydrat PF14031.6 KFH44812.1 - 6.6e-05 23.5 0.1 0.00027 21.5 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Cyt-b5 PF00173.28 KFH44813.1 - 5.4e-20 71.3 1.3 1.4e-19 70.0 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KFH44813.1 - 5.5e-11 42.9 19.7 5.5e-11 42.9 19.7 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KFH44813.1 - 0.082 13.1 0.2 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KFH44813.1 - 0.19 11.6 3.5 0.56 10.1 0.5 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly EF-hand_4 PF12763.7 KFH44814.1 - 4.2e-17 62.0 0.0 5.1e-06 26.4 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KFH44814.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2353 PF09789.9 KFH44814.1 - 0.49 9.7 22.1 0.088 12.2 0.5 2.9 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 KFH44814.1 - 0.86 8.4 29.5 0.35 9.7 12.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Med30 PF11315.8 KFH44814.1 - 1.7 8.8 10.4 3.6 7.8 10.4 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF3450 PF11932.8 KFH44814.1 - 3.3 6.9 22.2 3.4 6.9 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 KFH44814.1 - 3.4 7.9 31.8 0.28 11.5 20.4 3.6 2 1 0 2 2 2 0 Zinc finger-containing protein HAP1_N PF04849.13 KFH44814.1 - 3.6 6.7 26.9 2.1 7.5 18.9 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TFIID-18kDa PF02269.16 KFH44815.1 - 2.6e-18 65.8 0.1 4e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KFH44815.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KFH44815.1 - 0.019 15.4 1.4 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 FYDLN_acid PF09538.10 KFH44815.1 - 0.04 14.6 2.4 0.06 14.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CENP-T_C PF15511.6 KFH44815.1 - 0.058 13.5 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFH44815.1 - 0.07 13.4 0.4 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIP49 PF06068.13 KFH44816.1 - 1.2e-166 554.3 0.0 1.5e-166 553.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFH44816.1 - 1.1e-25 89.5 0.2 3.4e-25 88.0 0.2 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFH44816.1 - 3e-10 40.6 0.2 1.7e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH44816.1 - 3.3e-09 36.7 0.3 1.5e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH44816.1 - 0.00012 22.4 0.2 0.18 12.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFH44816.1 - 0.00053 20.4 0.1 0.0051 17.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFH44816.1 - 0.00091 19.6 1.9 0.11 12.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH44816.1 - 0.0019 18.5 0.1 0.0047 17.2 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KFH44816.1 - 0.0062 16.5 0.1 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFH44816.1 - 0.014 14.9 0.1 0.094 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFH44816.1 - 0.019 14.3 0.1 0.057 12.7 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KFH44816.1 - 0.021 15.3 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFH44816.1 - 0.028 14.1 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFH44816.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DnaB_C PF03796.15 KFH44816.1 - 0.033 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KFH44816.1 - 0.038 13.4 0.1 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFH44816.1 - 0.06 12.6 0.1 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFH44816.1 - 0.08 12.6 0.3 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain TFIID-31kDa PF02291.15 KFH44816.1 - 0.15 12.1 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit NACHT PF05729.12 KFH44816.1 - 0.19 11.7 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Uds1 PF15456.6 KFH44817.1 - 1.6e-41 141.5 2.3 1.6e-41 141.5 2.3 6.5 4 1 3 7 7 7 2 Up-regulated During Septation Spc7 PF08317.11 KFH44817.1 - 0.0048 15.8 16.0 0.0048 15.8 16.0 5.8 5 1 1 6 6 6 3 Spc7 kinetochore protein HMG_box PF00505.19 KFH44817.1 - 0.013 15.9 0.8 0.052 14.0 0.8 2.0 1 0 0 1 1 1 0 HMG (high mobility group) box DASH_Dam1 PF08653.10 KFH44817.1 - 0.71 9.7 2.4 8.2 6.3 0.0 3.8 3 1 0 3 3 3 0 DASH complex subunit Dam1 Cpn60_TCP1 PF00118.24 KFH44818.1 - 2.8e-171 570.5 1.6 3.2e-171 570.3 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIA PF03153.13 KFH44820.1 - 0.005 16.9 7.3 0.005 16.9 7.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ribosomal_L37 PF08561.10 KFH44820.1 - 0.0092 16.5 2.4 0.013 16.0 2.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 TMEM51 PF15345.6 KFH44820.1 - 0.031 14.1 3.5 0.036 13.9 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 KFH44820.1 - 0.058 13.0 13.8 0.085 12.5 13.8 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 KFH44820.1 - 0.063 12.0 0.5 0.056 12.2 0.5 1.1 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 KFH44820.1 - 0.1 11.4 10.3 0.13 11.1 10.3 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 KFH44820.1 - 0.12 13.4 3.4 0.22 12.5 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 KFH44820.1 - 0.13 10.8 5.9 0.17 10.3 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.8 KFH44820.1 - 0.28 10.9 3.5 0.51 10.1 3.5 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Roughex PF06020.11 KFH44820.1 - 0.35 9.9 5.5 0.4 9.7 5.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Pyr_redox_2 PF07992.14 KFH44822.1 - 1.9e-61 207.9 1.1 2.8e-61 207.3 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFH44822.1 - 1.4e-33 115.4 1.4 6.5e-33 113.3 0.4 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFH44822.1 - 4.2e-20 72.1 4.8 2.2e-19 69.8 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH44822.1 - 9.6e-14 51.3 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH44822.1 - 1e-06 28.1 0.0 0.00024 20.4 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KFH44822.1 - 0.00035 20.1 0.2 0.0038 16.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH44822.1 - 0.0004 19.2 1.1 0.074 11.7 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KFH44822.1 - 0.00085 18.5 0.1 0.0097 15.0 0.1 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFH44822.1 - 0.0016 17.8 1.3 0.67 9.2 0.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Ntox47 PF15540.6 KFH44822.1 - 0.0062 16.8 0.9 0.02 15.2 0.1 2.3 3 0 0 3 3 3 1 Bacterial toxin 47 Thi4 PF01946.17 KFH44822.1 - 0.039 13.2 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KFH44822.1 - 0.13 12.1 1.7 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2673 PF10880.8 KFH44822.1 - 0.34 11.1 0.9 7.7 6.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) 2-Hacid_dh_C PF02826.19 KFH44822.1 - 3.2 7.1 4.7 1.2 8.5 0.0 2.5 4 0 0 4 4 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribonuc_red_lgC PF02867.15 KFH44823.1 - 4.8e-194 645.8 0.0 6.2e-194 645.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFH44823.1 - 5.3e-25 87.2 0.0 1.4e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFH44823.1 - 2.4e-16 60.0 0.0 5.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain CENP-N PF05238.13 KFH44825.1 - 1.9e-128 429.3 0.0 2.2e-128 429.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like WD40 PF00400.32 KFH44826.1 - 7.6e-34 115.2 26.3 5.3e-07 30.2 0.1 12.0 14 0 0 14 14 14 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44826.1 - 3e-24 85.1 0.0 0.00037 20.7 0.0 8.6 3 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KFH44826.1 - 2e-14 53.8 0.0 3.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KFH44826.1 - 5.3e-11 42.2 14.0 4 7.5 0.0 11.6 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KFH44826.1 - 5.3e-07 29.6 0.1 0.9 9.2 0.0 4.7 5 0 0 5 5 5 3 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 KFH44826.1 - 4.8e-06 25.8 1.2 2.1 7.2 0.0 5.3 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KFH44826.1 - 0.00023 21.6 0.0 0.00059 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFH44826.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFH44826.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KFH44826.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea zf-HIT PF04438.16 KFH44827.1 - 1.8e-08 34.1 10.9 2.7e-08 33.6 10.9 1.3 1 0 0 1 1 1 1 HIT zinc finger ZZ PF00569.17 KFH44828.1 - 1.3e-09 37.7 6.8 2.3e-09 36.9 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KFH44828.1 - 3.6e-08 32.4 20.0 9e-05 21.8 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFH44828.1 - 2.2e-07 30.2 14.5 0.00022 20.9 0.1 4.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFH44828.1 - 2.9e-06 27.6 13.3 0.0016 18.8 0.2 4.6 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFH44828.1 - 0.001 18.5 18.4 0.056 13.0 0.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 KFH44828.1 - 0.14 12.1 0.0 0.67 9.9 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.16 KFH44829.1 - 2.6e-30 105.5 21.3 2.6e-30 105.5 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH44829.1 - 8.6e-10 37.7 8.2 6.8e-07 28.2 0.0 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KFH44829.1 - 4.3e-09 35.7 18.9 5.7e-06 25.5 0.1 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFH44829.1 - 0.4 9.5 11.3 0.45 9.3 3.1 2.7 2 1 0 2 2 2 0 MFS_1 like family DUF1656 PF07869.12 KFH44831.1 - 0.089 12.8 2.1 0.17 11.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Nop14 PF04147.12 KFH44831.1 - 0.42 8.8 15.5 0.52 8.5 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KFH44831.1 - 2.6 7.3 23.2 3.4 6.9 23.2 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFH44831.1 - 6.7 4.7 20.6 9 4.3 20.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 KFH44831.1 - 8.8 5.3 9.4 13 4.7 9.4 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 KFH44831.1 - 9 4.5 8.2 12 4.0 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KFH44832.1 - 5.1e-16 58.8 0.0 6.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44832.1 - 1.1e-07 31.5 0.0 1.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH44832.1 - 4.5e-06 26.2 0.0 6.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH44832.1 - 5.5e-05 23.2 0.1 8.7e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH44832.1 - 0.00031 20.2 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFH44832.1 - 0.00036 20.2 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFH44832.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase ADP_PFK_GK PF04587.15 KFH44832.1 - 0.027 13.1 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Phage_lysozyme2 PF18013.1 KFH44833.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage tail lysozyme Translin PF01997.16 KFH44834.1 - 3.6e-54 183.9 0.0 5.3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 KFH44834.1 - 0.053 14.1 1.4 0.18 12.4 1.4 1.9 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Baculo_p24 PF05073.12 KFH44834.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Glyco_hyd_65N_2 PF14498.6 KFH44835.1 - 9.3e-58 195.9 0.0 1.5e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain adh_short_C2 PF13561.6 KFH44836.1 - 1.7e-50 171.7 3.0 1.2e-49 169.0 3.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH44836.1 - 5.1e-39 133.8 1.2 1.9e-38 131.9 1.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH44836.1 - 1.4e-08 34.8 2.6 1.8e-08 34.5 0.4 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFH44836.1 - 0.00028 20.5 0.2 0.0031 17.0 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH44836.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFH44836.1 - 0.024 13.8 0.1 0.051 12.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFH44836.1 - 0.042 12.9 0.2 0.084 11.9 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_1 PF00561.20 KFH44837.1 - 1.4e-14 54.4 0.0 9.1e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH44837.1 - 3.2e-13 50.8 0.2 4.1e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH44837.1 - 1.6e-11 43.9 0.0 1.1e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFH44837.1 - 0.0042 16.6 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KFH44837.1 - 0.0084 16.2 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF1100 PF06500.11 KFH44837.1 - 0.057 12.2 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF640 PF04852.12 KFH44837.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF640) DUF2048 PF09752.9 KFH44837.1 - 0.09 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 FMN_red PF03358.15 KFH44838.1 - 9.3e-24 83.9 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFH44838.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Rad1 PF02144.16 KFH44839.1 - 1.9e-72 243.7 0.0 2.2e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Abhydrolase_6 PF12697.7 KFH44840.1 - 4.3e-12 47.1 1.1 1e-11 45.9 1.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH44840.1 - 1.3e-11 44.2 0.1 3.6e-11 42.8 0.1 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH44840.1 - 3.2e-10 40.1 0.1 6e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFH44840.1 - 5e-06 26.5 0.3 9e-06 25.7 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFH44840.1 - 0.0006 19.5 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFH44840.1 - 0.0013 18.3 0.1 0.008 15.7 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Cutinase PF01083.22 KFH44840.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.20 KFH44840.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PQ-loop PF04193.14 KFH44841.1 - 2.8e-24 84.6 4.2 1.1e-14 53.9 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1773 PF08593.10 KFH44842.1 - 3.5 8.7 8.7 8.4 7.5 0.1 4.3 3 0 0 3 3 3 0 Domain of unknown function NIBRIN_BRCT_II PF16508.5 KFH44844.1 - 5.1e-39 133.3 0.0 1.2e-38 132.0 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KFH44844.1 - 1.4e-10 41.4 0.1 2.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KFH44844.1 - 0.00011 22.0 0.2 0.00075 19.3 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KFH44844.1 - 0.0014 19.0 0.2 0.0072 16.7 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 KFH44844.1 - 0.027 14.8 0.0 0.57 10.5 0.0 2.6 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Beta_elim_lyase PF01212.21 KFH44845.1 - 2.2e-37 128.9 0.0 2.7e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFH44845.1 - 0.00019 20.7 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_64 PF16483.5 KFH44846.1 - 7.7e-117 390.7 0.0 9e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DNA_pol_B PF00136.21 KFH44847.1 - 0.0011 17.8 0.0 0.0011 17.7 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B RXT2_N PF08595.11 KFH44847.1 - 0.021 14.8 2.4 0.021 14.8 2.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KFH44847.1 - 0.033 13.9 10.4 0.033 13.9 10.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 KFH44847.1 - 0.042 13.5 0.4 0.042 13.5 0.4 1.1 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 KFH44847.1 - 0.077 12.9 1.4 0.075 12.9 1.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KFH44847.1 - 0.09 12.1 10.1 0.095 12.0 10.1 1.0 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 KFH44847.1 - 0.096 12.9 5.0 0.12 12.6 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KFH44847.1 - 0.14 12.5 12.4 0.17 12.3 12.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 KFH44847.1 - 0.32 9.2 3.0 0.33 9.2 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KFH44847.1 - 0.39 9.3 7.6 0.42 9.1 7.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCIP PF13324.6 KFH44847.1 - 0.6 9.7 4.4 0.54 9.8 4.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 KFH44847.1 - 0.84 8.7 14.0 0.95 8.5 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KFH44847.1 - 0.9 7.6 9.0 0.98 7.4 9.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 KFH44847.1 - 3.9 7.5 6.9 4.4 7.3 6.9 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.12 KFH44847.1 - 4.6 5.1 4.9 4.7 5.1 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TLD PF07534.16 KFH44848.1 - 5.2e-29 101.2 0.0 1e-28 100.3 0.0 1.5 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 KFH44848.1 - 1.7e-10 41.8 0.5 6.2e-10 40.0 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function TFIIE-A_C PF11521.8 KFH44848.1 - 2.2 8.6 10.5 1.9 8.9 4.7 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Peptidase_S9 PF00326.21 KFH44849.1 - 0.0002 20.9 0.2 0.00038 20.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFH44849.1 - 0.00049 20.0 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KFH44849.1 - 0.0049 16.4 1.0 0.0095 15.4 0.3 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 KFH44849.1 - 0.094 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.16 KFH44850.1 - 1.4e-30 106.5 89.6 3.5e-25 88.7 52.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH44850.1 - 6.9e-08 31.5 32.5 4.6e-06 25.5 16.2 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KFH44850.1 - 0.003 15.9 3.1 0.0065 14.8 3.1 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N_2 PF13602.6 KFH44851.1 - 5.9e-07 30.6 0.0 1.5e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH44851.1 - 1.2e-06 28.4 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 KFH44852.1 - 7.9e-09 35.5 10.7 1.3e-08 34.8 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH44852.1 - 8.4e-07 28.1 1.6 1.5e-06 27.3 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rep_fac-A_C PF08646.10 KFH44852.1 - 0.4 10.4 3.3 0.68 9.7 3.3 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Peptidase_S8 PF00082.22 KFH44853.1 - 2.9e-37 128.5 6.3 5.4e-37 127.7 6.3 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH44853.1 - 0.16 12.6 0.5 0.35 11.6 0.3 1.7 2 0 0 2 2 2 0 Peptidase inhibitor I9 THP2 PF09432.10 KFH44854.1 - 0.032 14.3 0.5 3.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 DUF4763 PF15960.5 KFH44854.1 - 0.04 13.2 1.7 0.089 12.1 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Macoilin PF09726.9 KFH44854.1 - 0.05 12.2 1.9 0.05 12.2 1.9 1.1 1 0 0 1 1 1 0 Macoilin family YPEB PF14620.6 KFH44854.1 - 0.055 12.8 0.7 0.065 12.6 0.7 1.1 1 0 0 1 1 1 0 YpeB sporulation Pkinase PF00069.25 KFH44855.1 - 4.2e-36 124.7 0.0 8.3e-36 123.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44855.1 - 5.2e-22 78.4 0.0 7.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH44855.1 - 0.0063 15.3 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH44855.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LSM PF01423.22 KFH44858.1 - 1.1e-16 60.3 0.1 1.2e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain GREB1 PF15782.5 KFH44859.1 - 9.5 3.2 6.8 10 3.1 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rad4 PF03835.15 KFH44860.1 - 9.7e-15 54.5 2.0 1.8e-14 53.7 2.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KFH44860.1 - 1.5e-10 41.5 2.9 3.3e-10 40.4 2.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_M28 PF04389.17 KFH44861.1 - 2.3e-42 144.9 0.1 3.5e-42 144.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH44861.1 - 2.1e-10 40.5 0.1 5.3e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFH44861.1 - 1.5e-06 28.1 0.0 3.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KFH44861.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MFS_1 PF07690.16 KFH44862.1 - 1e-34 120.1 23.8 1.7e-33 116.0 26.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFH44863.1 - 1.3e-43 149.3 57.1 3.3e-42 144.7 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH44863.1 - 6.5e-11 41.7 4.7 6.5e-11 41.7 4.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter LapA_dom PF06305.11 KFH44863.1 - 8.2 6.3 5.5 14 5.6 1.7 3.3 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2235 PF09994.9 KFH44864.1 - 6.9e-63 212.7 0.0 1e-62 212.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DnaJ-X PF14308.6 KFH44865.1 - 2.3e-79 265.7 0.4 2.3e-79 265.7 0.4 2.7 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 KFH44865.1 - 3.3e-26 91.2 0.9 1.2e-25 89.4 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KFH44867.1 - 2.9e-11 43.7 6.5 0.23 12.4 0.0 7.8 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH44867.1 - 3e-06 27.4 0.1 0.088 13.1 0.0 4.7 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH44867.1 - 0.0014 17.7 0.0 0.39 9.6 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFH44867.1 - 0.0033 17.0 0.6 0.084 12.4 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain Ada_Zn_binding PF02805.16 KFH44868.1 - 9.4e-31 105.7 7.8 1.4e-30 105.1 7.8 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 KFH44868.1 - 1.4e-06 28.4 0.1 3.5e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KFH44868.1 - 1e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family ketoacyl-synt PF00109.26 KFH44869.1 - 1.3e-60 205.1 0.0 3.7e-60 203.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH44869.1 - 1.1e-56 191.6 0.0 3.1e-56 190.1 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH44869.1 - 2.2e-56 191.3 1.5 8.1e-56 189.4 0.5 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH44869.1 - 8.2e-47 160.2 0.1 6.8e-46 157.2 0.1 2.3 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH44869.1 - 3.7e-33 114.0 0.0 9e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFH44869.1 - 3.8e-23 82.1 0.1 2.1e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KFH44869.1 - 2.1e-14 53.6 0.0 6.7e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH44869.1 - 1.3e-10 42.4 0.0 4.5e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFH44869.1 - 2.2e-10 40.3 0.0 2e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KFH44869.1 - 1.9e-05 24.9 0.1 4.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KFH44869.1 - 2.1e-05 24.4 0.2 5.2e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF5521 PF17659.1 KFH44869.1 - 0.14 10.0 3.8 0.21 9.4 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Mannosyl_trans PF05007.13 KFH44870.1 - 9.8e-78 261.6 14.0 1.3e-77 261.2 14.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFH44870.1 - 3e-10 39.7 13.4 4.2e-09 35.9 13.4 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3333 PF11812.8 KFH44870.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Bromodomain PF00439.25 KFH44871.1 - 9.3e-24 83.3 2.0 1.1e-23 83.1 0.8 1.7 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 KFH44871.1 - 1e-07 32.2 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH44871.1 - 2.6e-07 30.6 0.3 8.6e-07 28.9 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH44871.1 - 0.00012 22.4 0.4 0.00043 20.7 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NMT_C PF02799.15 KFH44873.1 - 6.9e-81 270.8 0.0 1e-80 270.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFH44873.1 - 7.1e-70 234.0 0.0 1.5e-69 232.9 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KFH44873.1 - 2.7e-06 27.5 0.1 0.00062 19.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Cut8 PF08559.10 KFH44873.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Acetyltransf_1 PF00583.25 KFH44873.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family NodA PF02474.15 KFH44873.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein A (NodA) PGA2 PF07543.12 KFH44873.1 - 0.32 11.0 6.8 0.77 9.7 6.8 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Ost5 PF05251.12 KFH44874.1 - 4.3e-18 65.3 9.6 5e-18 65.1 9.6 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Tri3 PF07428.11 KFH44875.1 - 1.4e-06 27.5 0.0 0.0005 19.1 0.0 2.1 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 PapA_C PF16911.5 KFH44875.1 - 0.063 13.4 0.2 0.21 11.7 0.0 2.0 2 1 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus LpqV PF17301.2 KFH44875.1 - 0.067 13.4 0.5 0.21 11.9 0.5 1.8 1 0 0 1 1 1 0 Putative lipoprotein LpqV SDA1 PF05285.12 KFH44878.1 - 0.016 14.7 3.3 0.016 14.7 3.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KFH44878.1 - 0.16 10.3 3.8 0.16 10.2 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KFH44878.1 - 0.8 9.0 14.6 1 8.6 14.6 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 KFH44878.1 - 0.99 9.5 6.9 1.3 9.1 6.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 KFH44878.1 - 1.4 7.1 7.3 1.5 7.0 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KFH44878.1 - 1.4 7.3 7.8 1.6 7.0 7.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Rol_Rep_N PF18106.1 KFH44879.1 - 0.089 13.1 0.0 0.098 13.0 0.0 1.2 1 1 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain Cyt-b5 PF00173.28 KFH44880.1 - 5.3e-15 55.3 0.0 8.6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 KFH44881.1 - 1.6e-98 330.4 35.7 1.9e-98 330.1 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH44881.1 - 1.1e-23 83.7 36.8 1.5e-23 83.3 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease ILVD_EDD PF00920.21 KFH44882.1 - 1e-141 473.1 0.0 3.9e-117 392.0 0.0 2.0 2 0 0 2 2 2 2 Dehydratase family GIIM PF08388.11 KFH44884.1 - 0.12 12.4 0.1 23 5.1 0.0 2.4 2 0 0 2 2 2 0 Group II intron, maturase-specific domain Gpr1_Fun34_YaaH PF01184.19 KFH44886.1 - 1.5e-88 295.9 14.9 1.7e-88 295.6 14.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HIG_1_N PF04588.13 KFH44887.1 - 2.3e-21 75.8 1.1 2.7e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region CAF1 PF04857.20 KFH44887.1 - 0.11 11.6 1.0 0.16 11.1 1.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF2514 PF10721.9 KFH44887.1 - 0.15 12.1 19.3 0.1 12.6 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4407 PF14362.6 KFH44887.1 - 0.18 11.2 11.9 0.25 10.7 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) O-ag_pol_Wzy PF14296.6 KFH44887.1 - 0.26 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4050 PF13259.6 KFH44887.1 - 0.51 10.6 4.6 0.98 9.7 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Vma12 PF11712.8 KFH44887.1 - 6.9 6.7 5.6 1.5e+02 2.4 0.0 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase U1snRNP70_N PF12220.8 KFH44887.1 - 9 7.0 17.6 0.36 11.5 2.2 3.5 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-RanBP PF00641.18 KFH44888.1 - 0.049 13.0 1.5 0.049 13.0 1.5 2.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others IBR PF01485.21 KFH44888.1 - 0.14 12.4 7.3 0.35 11.1 7.4 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain C6_DPF PF10170.9 KFH44888.1 - 0.34 11.3 4.8 0.69 10.3 4.8 1.4 1 0 0 1 1 1 0 Cysteine-rich domain DZR PF12773.7 KFH44888.1 - 0.53 10.3 8.2 4.5 7.4 8.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KFH44888.1 - 5.6 7.2 10.2 17 5.7 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain NAPRTase PF04095.16 KFH44889.1 - 9.8e-54 182.5 0.2 1.1e-27 97.3 0.5 2.2 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KFH44889.1 - 2.6e-36 124.8 0.0 4.9e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4013 PF13197.6 KFH44891.1 - 0.00015 21.7 2.0 0.00023 21.0 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Ribophorin_II PF05817.14 KFH44892.1 - 5.8e-29 101.1 0.0 7.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF5396 PF17374.2 KFH44892.1 - 0.089 10.6 0.1 0.11 10.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) BfiI_DBD PF18243.1 KFH44892.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain DAO PF01266.24 KFH44893.1 - 3.2e-35 122.3 2.5 3.8e-35 122.1 2.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH44893.1 - 0.00023 21.3 0.1 0.0007 19.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH44893.1 - 0.00048 19.3 0.2 0.00053 19.2 0.2 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFH44893.1 - 0.0098 16.4 0.1 0.023 15.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH44893.1 - 0.021 14.1 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH44893.1 - 0.034 13.4 1.3 0.06 12.6 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KFH44893.1 - 0.041 12.9 0.7 3.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KFH44893.1 - 0.042 13.1 0.1 0.077 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KFH44893.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.7 KFH44896.1 - 0.00053 19.8 0.0 0.0032 17.3 0.0 2.4 2 1 0 2 2 2 1 F-box-like DHDPS PF00701.22 KFH44897.1 - 3.2e-38 131.1 0.0 3.7e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-RING_2 PF13639.6 KFH44898.1 - 5.7e-09 36.2 3.5 5.7e-09 36.2 3.5 2.4 3 0 0 3 3 2 1 Ring finger domain zf-ANAPC11 PF12861.7 KFH44898.1 - 4.9e-06 26.5 1.9 4.9e-06 26.5 1.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFH44898.1 - 0.00031 21.0 3.4 0.00031 21.0 3.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFH44898.1 - 0.00048 19.8 4.4 0.0011 18.7 4.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain SWIM PF04434.17 KFH44898.1 - 0.00061 19.4 0.2 0.0012 18.5 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_UBOX PF13445.6 KFH44898.1 - 0.00072 19.5 1.6 0.0021 18.0 1.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH44898.1 - 0.0019 18.1 3.2 0.0019 18.1 3.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain FANCL_C PF11793.8 KFH44898.1 - 0.0023 18.1 5.7 0.0023 18.1 5.7 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 KFH44898.1 - 0.0032 17.3 5.1 0.006 16.4 5.1 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFH44898.1 - 0.0089 15.9 1.9 0.0089 15.9 1.9 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KFH44898.1 - 0.019 14.8 1.8 0.053 13.4 1.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KFH44898.1 - 0.18 11.7 3.5 0.077 12.9 0.7 1.8 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pol_alpha_B_N PF08418.10 KFH44898.1 - 1.8 8.5 3.5 2.4 8.1 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Prok-RING_4 PF14447.6 KFH44898.1 - 2.5 8.0 7.7 2.3 8.2 0.3 3.0 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFH44898.1 - 7.3 6.5 14.0 0.037 13.9 3.9 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ATAD4 PF15321.6 KFH44899.1 - 4.2 8.8 9.0 0.39 12.1 0.6 3.5 3 1 1 4 4 4 0 ATPase family AAA domain containing 4 3Beta_HSD PF01073.19 KFH44900.1 - 2e-11 43.4 0.0 4.6e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH44900.1 - 4e-11 42.9 0.2 9e-11 41.7 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFH44900.1 - 1.4e-09 37.5 0.1 1.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFH44900.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFH44900.1 - 2.6e-05 23.8 0.0 6.2e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFH44900.1 - 0.00012 21.7 0.1 0.00027 20.6 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KFH44900.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFH44900.1 - 0.024 14.1 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KFH44900.1 - 0.034 13.2 0.0 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_hydro_12 PF01670.16 KFH44902.1 - 8.3e-11 42.3 3.7 1.2e-10 41.8 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 BPTA PF17044.5 KFH44902.1 - 0.29 11.0 0.0 0.39 10.5 0.0 1.1 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A SQS_PSY PF00494.19 KFH44903.1 - 1.1e-38 133.2 0.0 1.5e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF5320 PF17253.2 KFH44905.1 - 6.8 7.8 15.4 1.7e+02 3.4 12.8 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5320) HLH PF00010.26 KFH44907.1 - 6.2e-12 45.3 0.5 1.4e-11 44.2 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LPD7 PF18821.1 KFH44907.1 - 2 8.6 5.6 3.8 7.7 0.6 2.6 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 PAT1 PF09770.9 KFH44907.1 - 8.7 4.5 23.5 12 4.0 23.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3543 PF12063.8 KFH44908.1 - 3.8e-90 301.7 0.1 6e-90 301.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KFH44908.1 - 2.5e-60 204.1 0.0 4.5e-60 203.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44908.1 - 2.9e-41 141.4 0.0 5.7e-41 140.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFH44909.1 - 1.5e-49 168.8 0.0 2.1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH44909.1 - 3.1e-23 82.4 0.0 4.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFH44909.1 - 3.2e-11 43.4 0.0 7.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFH44909.1 - 1.1e-05 24.9 0.0 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFH44909.1 - 0.042 13.2 0.0 0.09 12.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.24 KFH44910.1 - 9.8e-33 113.5 4.7 2e-32 112.5 4.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH44910.1 - 4.2e-21 75.0 0.0 9.2e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFH44910.1 - 2e-20 73.6 0.1 5.8e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH44910.1 - 1.4e-13 51.3 7.1 2e-13 50.7 4.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Xin PF08043.12 KFH44911.1 - 0.04 13.5 0.2 0.074 12.7 0.2 1.5 1 0 0 1 1 1 0 Xin repeat CLTH PF10607.9 KFH44912.1 - 1.2e-29 103.2 0.0 1.8e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFH44912.1 - 0.00054 19.8 0.1 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 LisH V-ATPase_G_2 PF16999.5 KFH44912.1 - 0.38 11.2 3.9 0.92 10.0 0.8 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AcetylCoA_hydro PF02550.15 KFH44913.1 - 2.2e-47 161.6 0.0 3.4e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KFH44913.1 - 7.6e-41 139.6 0.0 1.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RNA_pol_I_A49 PF06870.12 KFH44914.1 - 1e-98 330.8 1.4 1.2e-98 330.6 1.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor NDUF_B12 PF08122.12 KFH44915.1 - 8.7e-24 83.3 1.4 1.2e-23 82.9 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family LPMO_10 PF03067.15 KFH44916.1 - 1.4e-07 32.4 0.0 1.4e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading NADH-G_4Fe-4S_3 PF10588.9 KFH44916.1 - 0.069 12.7 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Pribosyltran PF00156.27 KFH44917.1 - 3.8e-06 26.5 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2OG-FeII_Oxy PF03171.20 KFH44919.1 - 1.2e-13 51.4 0.0 1.9e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFH44919.1 - 1.3e-08 35.5 0.0 2.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal dCMP_cyt_deam_1 PF00383.23 KFH44920.1 - 6.9e-07 29.1 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFH44920.1 - 5.4e-06 26.2 0.0 6.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase HetR_C PF18460.1 KFH44920.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF2431 PF10354.9 KFH44922.1 - 2.1e-56 190.8 0.0 1.4e-55 188.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) PRIMA1 PF16101.5 KFH44922.1 - 0.009 16.0 10.1 0.12 12.4 8.4 2.3 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 Zip PF02535.22 KFH44922.1 - 0.81 8.8 5.8 5.1 6.2 1.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter TRAP_alpha PF03896.16 KFH44922.1 - 3.9 6.6 4.8 6.9 5.8 4.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KFH44922.1 - 4.4 5.3 9.4 6.3 4.8 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fungus-induced PF10917.8 KFH44922.1 - 5.4 7.4 11.1 0.21 11.9 1.3 2.7 2 0 0 2 2 2 0 Fungus-induced protein CAP_N PF01213.19 KFH44922.1 - 7.9 5.9 16.2 0.38 10.2 10.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GCR1_C PF12550.8 KFH44923.1 - 5.3e-16 58.7 0.3 9.7e-16 57.9 0.3 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HCR PF07111.12 KFH44923.1 - 0.0037 15.4 0.9 0.0054 14.9 0.9 1.1 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) Csm1_N PF18504.1 KFH44923.1 - 0.013 15.9 3.1 1.2 9.6 1.3 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain TSC22 PF01166.18 KFH44923.1 - 0.036 14.4 4.4 35 4.8 0.0 4.3 2 2 2 4 4 4 0 TSC-22/dip/bun family UPF0242 PF06785.11 KFH44923.1 - 0.043 13.9 2.9 0.078 13.1 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 KFH44923.1 - 0.044 13.3 0.4 0.08 12.4 0.4 1.3 1 0 0 1 1 1 0 Leucine zipper DivIVA PF05103.13 KFH44923.1 - 0.072 13.2 1.1 0.16 12.0 1.1 1.5 1 0 0 1 1 1 0 DivIVA protein bZIP_1 PF00170.21 KFH44923.1 - 0.081 13.0 3.6 3.6 7.8 0.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF4618 PF15397.6 KFH44923.1 - 0.082 12.3 0.7 0.14 11.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Cep57_CLD_2 PF14197.6 KFH44923.1 - 0.21 11.7 4.8 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KFH44923.1 - 0.57 10.8 2.1 28 5.4 2.1 2.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KFH44923.1 - 0.6 9.9 3.8 7.3 6.4 1.4 2.7 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 KFH44923.1 - 0.91 9.6 7.1 6.3 6.9 0.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KFH44923.1 - 0.95 10.0 8.5 1.6 9.2 1.0 2.8 1 1 1 2 2 2 0 Cell division protein ZapB TolA_bind_tri PF16331.5 KFH44923.1 - 4.3 7.5 8.8 2 8.6 2.6 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation Vps51 PF08700.11 KFH44924.1 - 8.3e-12 45.0 0.0 2.8e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Abhydrolase_1 PF00561.20 KFH44925.1 - 9.9e-37 127.0 0.0 1.9e-36 126.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH44925.1 - 0.00022 21.9 0.0 0.00059 20.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFH44925.1 - 0.0074 16.4 0.3 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KFH44925.1 - 0.17 11.2 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ketoacyl-synt PF00109.26 KFH44926.1 - 4.7e-62 209.8 0.0 6.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KFH44926.1 - 5.5e-06 25.9 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFH44926.1 - 0.00081 19.2 0.4 0.0018 18.1 0.4 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Voltage_CLC PF00654.20 KFH44927.1 - 7.7e-88 295.1 21.6 7.7e-88 295.1 21.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.9 KFH44927.1 - 1.3 8.9 6.6 4.5 7.3 6.6 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence p450 PF00067.22 KFH44928.1 - 1.5e-51 175.7 0.0 2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFH44930.1 - 8.4e-56 189.6 0.0 1.1e-55 189.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThiF PF00899.21 KFH44931.1 - 1.7e-26 93.1 0.0 2.3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF1476 PF07345.11 KFH44932.1 - 0.096 13.1 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta CDH-cyt PF16010.5 KFH44933.1 - 2.7e-46 157.5 0.1 4.5e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase TonB_N PF16031.5 KFH44933.1 - 0.02 15.4 8.8 0.049 14.1 8.8 1.6 1 0 0 1 1 1 0 TonB polyproline region AMP-binding PF00501.28 KFH44934.1 - 4.4e-66 223.2 0.0 5.8e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH44934.1 - 2.6e-06 28.3 0.0 5.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KFH44934.1 - 0.0033 16.2 0.2 0.83 8.3 0.7 2.1 2 0 0 2 2 2 2 Condensation domain FAD_binding_3 PF01494.19 KFH44935.1 - 3.3e-08 33.2 1.1 0.041 13.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFH44935.1 - 0.0021 18.3 0.1 0.018 15.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH44935.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH44935.1 - 0.081 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH44935.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KFH44936.1 - 3e-06 26.4 35.2 5.9e-06 25.4 27.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 KFH44937.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mito_fiss_reg PF05308.11 KFH44937.1 - 0.75 9.8 2.6 1 9.4 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Haem_oxygenas_2 PF14518.6 KFH44938.1 - 9.5e-06 25.5 0.1 2.7e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Iron-containing redox enzyme SAM_KSR1 PF13543.6 KFH44939.1 - 0.016 15.3 0.9 0.028 14.6 0.9 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Zn_clus PF00172.18 KFH44939.1 - 0.57 10.3 7.9 1.4 9.1 7.9 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KFH44940.1 - 1.7e-16 60.9 0.0 2.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH44940.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase CENP-P PF13096.6 KFH44941.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P T2SSM PF04612.12 KFH44941.1 - 0.63 10.1 3.2 1.8 8.6 3.2 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Fungal_trans PF04082.18 KFH44942.1 - 4.7e-31 107.8 0.0 1.2e-30 106.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH44942.1 - 4.8e-06 26.6 7.2 9.5e-06 25.6 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KFH44943.1 - 2e-06 27.6 0.1 5.3e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like Melibiase_2_C PF17450.2 KFH44943.1 - 0.0047 17.1 0.0 0.3 11.4 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase A C-terminal beta sandwich domain CAF1 PF04857.20 KFH44944.1 - 7.2e-25 87.8 0.0 1.7e-11 43.9 0.1 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KFH44944.1 - 0.16 12.6 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 RFX DNA-binding domain APH PF01636.23 KFH44945.1 - 6.7e-15 55.7 0.1 1.1e-14 54.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Beta_helix PF13229.6 KFH44945.1 - 0.0012 18.8 13.7 0.0019 18.0 13.7 1.3 1 0 0 1 1 1 1 Right handed beta helix region ECH_1 PF00378.20 KFH44946.1 - 1.2e-18 67.4 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH44946.1 - 6.7e-14 52.1 0.0 7.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SUIM_assoc PF16619.5 KFH44947.1 - 0.00017 21.6 0.0 0.0017 18.4 0.0 2.8 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Mt_ATP-synt_D PF05873.12 KFH44947.1 - 0.059 13.2 2.9 0.12 12.2 2.9 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Oxidored-like PF09791.9 KFH44948.1 - 2.7e-24 84.6 4.8 2.7e-24 84.6 4.8 2.5 3 0 0 3 3 3 1 Oxidoreductase-like protein, N-terminal Acetyltransf_2 PF00797.17 KFH44949.1 - 1.9e-29 103.1 0.0 2.3e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase CDH-cyt PF16010.5 KFH44950.1 - 9.6e-18 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KFH44950.1 - 1.5e-08 34.4 2.0 3.2e-08 33.3 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KFH44950.1 - 6e-05 23.2 11.2 0.00015 21.9 11.2 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF5079 PF16882.5 KFH44950.1 - 0.099 12.5 2.4 0.15 11.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) Collectrin PF16959.5 KFH44950.1 - 0.11 12.3 0.2 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Renal amino acid transporter SRI PF08236.11 KFH44952.1 - 2e-22 79.2 7.6 4.7e-22 78.0 7.6 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KFH44952.1 - 3.1e-17 63.5 0.2 3.1e-17 63.5 0.2 3.6 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KFH44952.1 - 1.9e-10 40.6 7.3 1.9e-10 40.6 7.3 2.4 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KFH44952.1 - 2.3e-06 27.6 0.7 6.1e-06 26.2 0.7 1.8 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KFH44952.1 - 9.6e-06 25.5 0.2 3.4e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DPM3 PF08285.11 KFH44954.1 - 4.5e-36 122.9 0.1 5e-36 122.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sulfotransfer_4 PF17784.1 KFH44955.1 - 3.2e-41 141.5 0.0 4.6e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain 2OG-FeII_Oxy PF03171.20 KFH44955.1 - 4.5e-08 33.5 0.0 1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFH44955.1 - 7.9e-05 23.4 0.0 0.00013 22.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.22 KFH44956.1 - 5e-53 180.5 0.0 6.6e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 KFH44956.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein Cation_ATPase_C PF00689.21 KFH44958.1 - 2.8e-46 157.5 6.0 2.8e-46 157.5 6.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFH44958.1 - 2.6e-35 121.6 0.9 2.6e-35 121.6 0.9 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFH44958.1 - 2.9e-22 80.0 0.1 9.8e-22 78.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH44958.1 - 2.8e-21 75.4 0.0 5.5e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFH44958.1 - 1.3e-12 47.2 0.1 8e-10 38.3 0.0 2.8 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH44958.1 - 0.00064 19.5 0.2 0.0014 18.4 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFH44958.1 - 0.013 14.3 2.2 0.027 13.3 2.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HAD PF12710.7 KFH44958.1 - 0.099 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transferase PF02458.15 KFH44959.1 - 1.3e-11 43.9 0.0 2.2e-10 39.8 0.0 2.2 2 1 0 2 2 2 2 Transferase family Sas10 PF09368.10 KFH44960.1 - 1.3e-28 99.2 7.5 1.3e-28 99.2 7.5 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFH44960.1 - 5.7e-09 36.5 1.2 1.3e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CwsA PF10814.8 KFH44960.1 - 0.061 13.5 0.8 0.2 11.8 0.8 1.8 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA SMYLE_N PF18615.1 KFH44961.1 - 0.25 10.9 0.9 0.35 10.4 0.9 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Carn_acyltransf PF00755.20 KFH44962.1 - 5.2e-107 358.9 0.0 7e-107 358.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PS-DH PF14765.6 KFH44962.1 - 6.7e-50 170.0 0.0 1.1e-49 169.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH44962.1 - 3.6e-48 164.7 0.4 8.6e-48 163.5 0.4 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH44962.1 - 3.9e-39 134.4 0.0 1.2e-38 132.8 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFH44962.1 - 3.2e-37 127.2 0.1 1.4e-36 125.1 0.1 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH44962.1 - 3e-11 44.5 0.0 2.3e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KFH44962.1 - 3e-11 43.8 0.1 5.4e-10 39.7 0.0 3.1 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFH44962.1 - 2.8e-10 40.0 0.2 1.1e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KFH44962.1 - 3e-09 37.1 0.9 9e-09 35.6 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 KFH44962.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 KFH44962.1 - 7.4e-05 22.4 0.0 0.00022 20.9 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KFH44962.1 - 0.00038 20.4 0.1 0.0034 17.4 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH44962.1 - 0.001 19.7 0.0 0.01 16.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KFH44962.1 - 0.0023 17.1 0.0 0.0053 15.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_N PF08240.12 KFH44962.1 - 0.0076 16.1 0.3 0.018 14.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KFH44962.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_3 PF00202.21 KFH44963.1 - 6.2e-114 380.8 0.0 7.5e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFH44963.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Lsr2 PF11774.8 KFH44964.1 - 0.0061 16.7 0.3 0.009 16.1 0.3 1.3 1 0 0 1 1 1 1 Lsr2 Aida_N PF08910.10 KFH44964.1 - 0.022 15.2 0.5 0.022 15.2 0.5 2.1 2 0 0 2 2 2 0 Aida N-terminus tRNA-synt_1c PF00749.21 KFH44964.1 - 0.024 13.5 0.8 0.031 13.2 0.8 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain FAD_binding_4 PF01565.23 KFH44965.1 - 3.1e-22 78.8 3.6 5.9e-22 77.9 3.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH44965.1 - 1.3e-10 41.2 0.7 2.8e-10 40.1 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KFH44965.1 - 0.042 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aldo_ket_red PF00248.21 KFH44966.1 - 1.9e-51 175.0 0.0 2.4e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mob1_phocein PF03637.17 KFH44967.1 - 8.5e-39 133.3 0.2 3.4e-38 131.3 0.2 1.8 1 1 0 1 1 1 1 Mob1/phocein family ATP-synt_10 PF05176.14 KFH44968.1 - 1.4e-78 263.7 0.0 1.8e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 KFH44969.1 - 3.9e-10 39.9 0.2 3.9e-10 39.9 0.2 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Atg14 PF10186.9 KFH44969.1 - 0.0042 16.2 6.8 0.0054 15.9 6.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 KFH44969.1 - 0.068 12.5 10.5 0.053 12.8 8.2 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KFH44969.1 - 1.7 8.8 6.2 3.7 7.7 0.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KFH44969.1 - 4.2 5.8 7.2 5.5 5.4 7.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KFH44969.1 - 8.8 6.9 12.4 5.9 7.4 10.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3712 PF12505.8 KFH44970.1 - 5.1e-25 88.1 3.5 5.4e-25 88.1 1.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Baculo_11_kDa PF06143.11 KFH44970.1 - 0.029 14.0 0.6 0.064 12.8 0.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family RimK PF08443.11 KFH44970.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain UPF0552 PF10574.9 KFH44970.1 - 0.13 11.6 0.1 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Arp2/3-interacting proteins Arpin DUF3357 PF11837.8 KFH44970.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RED_N PF07808.13 KFH44971.1 - 1.3e-07 31.5 11.1 1.3e-07 31.5 11.1 2.9 3 1 0 3 3 3 1 RED-like protein N-terminal region GvpG PF05120.12 KFH44971.1 - 3 7.9 5.8 0.64 10.1 0.6 2.5 2 0 0 2 2 2 0 Gas vesicle protein G Stk19 PF10494.9 KFH44972.1 - 1.4e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 MarR_2 PF12802.7 KFH44972.1 - 0.0057 16.5 1.4 0.02 14.8 1.3 2.0 2 0 0 2 2 2 1 MarR family Mito_fiss_reg PF05308.11 KFH44972.1 - 0.25 11.4 6.3 0.44 10.6 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF737 PF05300.11 KFH44972.1 - 1.2 9.4 3.7 2.2 8.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CAP_N PF01213.19 KFH44972.1 - 2.6 7.4 9.0 3.9 6.9 9.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ORC6 PF05460.13 KFH44972.1 - 5.4 6.2 9.3 9.5 5.4 9.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Arf PF00025.21 KFH44973.1 - 2.7e-56 189.7 0.5 2.4e-38 131.3 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KFH44973.1 - 5.4e-09 35.7 0.1 0.00037 20.0 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 KFH44973.1 - 6e-05 23.2 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFH44973.1 - 6.6e-05 22.2 0.1 0.06 12.5 0.1 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFH44973.1 - 0.00034 20.0 0.1 0.0057 16.0 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KFH44973.1 - 0.0006 19.4 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 2 Ras family 6PF2K PF01591.18 KFH44973.1 - 0.042 13.2 0.8 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 KFH44973.1 - 0.045 13.8 0.5 6.3 6.9 0.1 2.1 1 1 1 2 2 2 0 50S ribosome-binding GTPase Mito_carr PF00153.27 KFH44974.1 - 2.2e-60 200.6 0.1 9.9e-20 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_6 PF08036.11 KFH44974.1 - 0.023 14.7 1.9 5.2 7.2 0.4 2.5 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide zf-C2H2 PF00096.26 KFH44975.1 - 0.0039 17.6 4.1 0.29 11.7 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH44975.1 - 0.023 15.5 2.2 6.8 7.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KFH44975.1 - 0.057 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L6e PF01159.19 KFH44976.1 - 1.5e-37 128.5 0.3 1.5e-37 128.5 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e AAA_22 PF13401.6 KFH44977.1 - 8.4e-15 55.3 0.0 2.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH44977.1 - 4.1e-13 50.1 0.3 5.1e-12 46.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFH44977.1 - 1.9e-10 41.3 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFH44977.1 - 7.4e-08 32.9 0.2 6e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 KFH44977.1 - 8.6e-07 28.9 1.0 3.7e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KFH44977.1 - 1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 KFH44977.1 - 7.6e-05 22.2 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 KFH44977.1 - 0.00066 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 KFH44977.1 - 0.001 18.3 0.0 0.0026 17.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 KFH44977.1 - 0.0018 18.1 0.4 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH44977.1 - 0.0019 18.0 0.1 0.0078 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFH44977.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.6 KFH44977.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.9 KFH44977.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 KFH44977.1 - 0.023 13.5 0.2 0.047 12.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH44977.1 - 0.03 14.7 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KFH44977.1 - 0.054 12.7 0.0 0.082 12.1 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain RNA12 PF10443.9 KFH44977.1 - 0.057 12.1 0.1 0.46 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein NTPase_1 PF03266.15 KFH44977.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KFH44977.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Torsin PF06309.11 KFH44977.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 KFH44977.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain p450 PF00067.22 KFH44978.1 - 2.2e-76 257.5 0.0 2.7e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSCB_C PF07743.13 KFH44979.1 - 1.1e-19 70.7 8.9 1.1e-19 70.7 8.9 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KFH44979.1 - 1.7e-05 24.9 0.1 3.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L29 PF00831.23 KFH44980.1 - 1.7e-17 63.1 0.3 1.7e-17 63.1 0.3 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein E1-E2_ATPase PF00122.20 KFH44981.1 - 2e-48 164.3 1.8 2e-48 164.3 1.8 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFH44981.1 - 3e-26 93.0 3.8 7.2e-26 91.8 3.8 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3405 PF11885.8 KFH44982.1 - 1.1e-230 766.7 0.4 1.3e-230 766.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) FancD2 PF14631.6 KFH44982.1 - 0.021 12.3 4.5 0.028 11.8 4.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MCM_bind PF09739.9 KFH44982.1 - 0.19 10.1 4.3 0.27 9.6 4.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RNA_pol_Rpc4 PF05132.14 KFH44982.1 - 0.2 12.1 3.3 0.49 10.8 3.3 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 ASD2 PF08687.11 KFH44982.1 - 0.31 10.5 3.4 0.47 10.0 3.4 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FAM60A PF15396.6 KFH44982.1 - 0.35 10.9 5.2 0.61 10.1 5.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 KFH44982.1 - 6.1 5.5 5.1 9.5 4.9 5.1 1.2 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 KFH44984.1 - 6.3e-14 51.6 0.2 1.1e-05 25.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH44984.1 - 0.024 14.7 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Sulfate_transp PF00916.20 KFH44985.1 - 4e-55 187.1 9.5 6e-55 186.5 9.5 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KFH44985.1 - 3e-16 59.3 0.0 5.7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KFH44985.1 - 1.7e-10 40.6 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Proteasom_Rpn13 PF04683.13 KFH44987.1 - 1.3e-26 92.9 0.0 2.1e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KFH44987.1 - 3.6e-11 43.2 0.3 7.5e-10 39.0 0.2 2.4 2 1 0 2 2 2 1 UCH-binding domain L27_2 PF09045.10 KFH44987.1 - 7.3e-05 22.6 0.3 0.00017 21.4 0.3 1.6 1 0 0 1 1 1 1 L27_2 DUF3074 PF11274.8 KFH44990.1 - 2.5e-40 138.4 0.7 3.6e-40 137.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Mer2 PF09074.10 KFH44991.1 - 0.019 14.8 1.3 0.019 14.8 1.3 2.0 2 1 0 2 2 2 0 Mer2 DUF1770 PF08589.10 KFH44991.1 - 0.088 13.8 4.6 0.24 12.4 4.1 2.2 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Rx_N PF18052.1 KFH44991.1 - 1.1 9.6 5.5 1.1 9.6 0.7 2.8 1 1 2 3 3 3 0 Rx N-terminal domain DUF5082 PF16888.5 KFH44991.1 - 1.8 8.9 8.5 0.78 10.0 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) AATF-Che1 PF13339.6 KFH44991.1 - 1.9 9.2 13.6 1.8e+02 2.8 13.4 2.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor FlxA PF14282.6 KFH44991.1 - 3.2 7.8 9.4 0.2 11.7 3.4 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF2968 PF11180.8 KFH44991.1 - 3.5 7.2 16.4 0.14 11.8 8.2 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.8 KFH44991.1 - 7.8 6.6 15.8 0.33 11.0 7.0 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KFH44991.1 - 8.4 6.7 15.7 2.9 8.1 10.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mito_carr PF00153.27 KFH44992.1 - 4.1e-65 215.7 0.2 2.1e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 KFH44993.1 - 2e-05 24.6 9.4 3.9e-05 23.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KFH44994.1 - 7.2e-18 64.1 45.5 5.6e-06 26.5 0.3 7.9 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFH44994.1 - 2.5e-13 49.7 50.4 0.00023 21.4 0.5 7.7 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH44994.1 - 9.8e-10 38.4 52.1 0.0038 17.9 0.4 7.8 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH44994.1 - 5.7e-07 29.4 29.7 0.0033 17.4 0.6 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFH44994.1 - 0.00028 21.6 15.4 0.0013 19.4 2.7 3.6 1 1 3 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFH44994.1 - 0.00065 19.9 2.0 0.00065 19.9 2.0 5.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFH44994.1 - 0.19 11.6 3.9 2.7 7.8 0.1 3.0 2 0 0 2 2 2 0 GAGA factor zf_ZIC PF18366.1 KFH44994.1 - 0.23 11.6 6.9 2.3 8.4 0.0 3.3 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 KFH44994.1 - 0.31 10.9 0.0 0.31 10.9 0.0 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-met PF12874.7 KFH44994.1 - 4.6 7.8 19.5 0.16 12.4 0.6 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type EF1_GNE PF00736.19 KFH44995.1 - 1.2e-33 115.2 1.4 2e-33 114.4 1.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFH44995.1 - 3.9e-12 46.4 11.9 3.9e-12 46.4 11.9 2.2 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KFH44995.1 - 2.2e-05 24.6 0.6 0.00011 22.3 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH44995.1 - 0.00012 22.2 0.3 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 KFH44995.1 - 0.016 15.7 1.2 0.024 15.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) UBA2_C PF16195.5 KFH44995.1 - 0.023 15.4 4.5 0.045 14.4 4.5 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Glyco_hydro_10 PF00331.20 KFH44996.1 - 6.6e-104 347.5 0.1 7.6e-104 347.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 EMP24_GP25L PF01105.24 KFH44997.1 - 3.8e-41 141.0 0.2 4.3e-41 140.8 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SHR3_chaperone PF08229.11 KFH44998.1 - 6e-63 211.2 0.0 8.7e-63 210.7 0.0 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KFH44998.1 - 0.045 13.7 0.1 0.093 12.7 0.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5453) FMN_dh PF01070.18 KFH44999.1 - 5e-105 351.3 0.0 6e-105 351.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFH44999.1 - 2.7e-20 72.3 0.0 8.8e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KFH44999.1 - 1.4e-07 30.9 0.2 4.1e-05 22.7 0.0 2.7 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFH44999.1 - 3.4e-07 29.8 0.1 6.3e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFH44999.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 KFH44999.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 KFH44999.1 - 0.021 14.2 0.5 0.037 13.4 0.5 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KFH44999.1 - 0.046 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TspO_MBR PF03073.15 KFH45000.1 - 5.6e-48 162.4 8.7 6.8e-48 162.1 8.7 1.1 1 0 0 1 1 1 1 TspO/MBR family IMS PF00817.20 KFH45001.1 - 3.3e-39 134.3 0.0 6.5e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KFH45001.1 - 6.1e-28 97.1 1.8 1.8e-27 95.6 1.8 1.9 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KFH45001.1 - 1.4e-12 48.4 0.0 2.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KFH45001.1 - 2.3e-11 42.7 7.8 2e-05 23.9 1.0 3.8 4 0 0 4 4 4 2 Ubiquitin binding region BRCT_2 PF16589.5 KFH45001.1 - 1.6e-08 34.8 0.0 5.4e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFH45001.1 - 0.0005 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 KFH45001.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 minimal CRISPR polymerase domain LIG3_BRCT PF16759.5 KFH45001.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DUF1805 PF08827.11 KFH45001.1 - 0.022 15.1 0.0 0.08 13.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MgtE_N PF03448.17 KFH45001.1 - 0.053 14.1 6.1 1.9 9.1 0.0 4.2 5 0 0 5 5 4 0 MgtE intracellular N domain EnY2 PF10163.9 KFH45001.1 - 0.076 13.4 1.9 13 6.2 0.0 3.6 4 0 0 4 4 3 0 Transcription factor e(y)2 FliG_M PF14841.6 KFH45001.1 - 0.41 10.9 2.2 43 4.4 0.1 3.6 4 0 0 4 4 4 0 FliG middle domain Cullin PF00888.22 KFH45003.1 - 2.5e-22 79.2 0.0 4.2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KFH45003.1 - 2.3e-21 76.0 0.0 6.5e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Peptidase_M49 PF03571.15 KFH45004.1 - 2.2e-242 805.4 0.0 2.6e-242 805.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 ALIX_LYPXL_bnd PF13949.6 KFH45004.1 - 0.19 11.0 0.4 5 6.3 0.2 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV LprI PF07007.12 KFH45004.1 - 0.22 12.2 0.5 0.88 10.3 0.6 1.9 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Arrestin_N PF00339.29 KFH45005.1 - 2.5e-17 63.3 0.0 1.5e-15 57.5 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFH45005.1 - 1e-05 26.0 0.1 9.7e-05 22.8 0.1 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain HCNGP PF07818.13 KFH45007.1 - 6.2e-32 110.1 0.0 8.5e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein Sld5 PF05916.11 KFH45008.1 - 1.3e-12 48.2 0.0 1.7e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KFH45008.1 - 0.048 14.5 0.0 0.33 11.8 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Pkr1 PF08636.10 KFH45009.1 - 7.4e-31 106.1 3.8 9.2e-31 105.8 3.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Mem_trans PF03547.18 KFH45009.1 - 0.089 11.2 0.0 0.099 11.0 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein FHIPEP PF00771.20 KFH45009.1 - 0.15 10.5 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family SHR3_chaperone PF08229.11 KFH45009.1 - 0.43 9.5 1.6 0.8 8.7 1.5 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 AAA_33 PF13671.6 KFH45010.1 - 9.6e-13 48.5 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KFH45010.1 - 1.6e-12 47.8 0.0 2.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KFH45010.1 - 7.8e-11 42.6 0.1 3e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFH45010.1 - 1.6e-07 31.8 0.0 4.8e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFH45010.1 - 2.3e-07 31.3 0.0 7.6e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFH45010.1 - 3.8e-07 30.2 0.0 6.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KFH45010.1 - 2.6e-06 27.3 0.0 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 KFH45010.1 - 1.1e-05 25.3 0.1 0.018 14.9 0.0 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 KFH45010.1 - 3.5e-05 24.2 0.0 4.5e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFH45010.1 - 0.00016 22.0 0.0 0.0002 21.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFH45010.1 - 0.00018 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFH45010.1 - 0.00087 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KFH45010.1 - 0.00091 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KFH45010.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.6 KFH45010.1 - 0.002 18.3 0.0 0.015 15.5 0.0 2.2 1 1 0 2 2 2 1 Cytidylate kinase-like family PRK PF00485.18 KFH45010.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KFH45010.1 - 0.0031 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KFH45010.1 - 0.0033 17.5 0.0 0.0097 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain CobU PF02283.16 KFH45010.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.8 3 0 0 3 3 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.27 KFH45010.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 KFH45010.1 - 0.0039 16.5 0.0 0.0084 15.4 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin CoaE PF01121.20 KFH45010.1 - 0.0085 15.8 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 1 1 Dephospho-CoA kinase ADK PF00406.22 KFH45010.1 - 0.013 15.6 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Thymidylate_kin PF02223.17 KFH45010.1 - 0.014 15.1 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 KFH45010.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 KFH45010.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 KFH45010.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFH45010.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KFH45010.1 - 0.022 14.5 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KFH45010.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 KFH45010.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFH45010.1 - 0.045 13.0 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KFH45010.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 KFH45010.1 - 0.05 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_PrkA PF08298.11 KFH45010.1 - 0.053 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_29 PF13555.6 KFH45010.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFH45010.1 - 0.056 13.8 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFH45010.1 - 0.058 13.1 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_LMP1 PF05297.11 KFH45010.1 - 0.059 12.6 0.8 0.076 12.2 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) AAA_11 PF13086.6 KFH45010.1 - 0.087 12.6 0.0 0.3 10.8 0.0 1.7 1 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KFH45010.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase1 PF18748.1 KFH45010.1 - 0.12 11.9 0.0 7 6.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 RhoGEF PF00621.20 KFH45011.1 - 3.9e-31 108.7 0.0 8.2e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KFH45011.1 - 2.2e-10 40.6 0.4 7.4e-10 38.9 0.4 1.8 1 0 0 1 1 1 1 BAR domain LPD13 PF18825.1 KFH45011.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 Kinesin PF00225.23 KFH45012.1 - 8.2e-95 317.5 0.0 8.2e-95 317.5 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFH45012.1 - 3.7e-22 78.9 0.0 1.2e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KFH45012.1 - 0.036 13.9 0.4 0.036 13.9 0.4 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KFH45012.1 - 0.12 11.7 12.6 0.12 11.7 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFB6 PF17110.5 KFH45012.1 - 0.18 11.6 4.9 0.42 10.3 4.9 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TAFII55_N PF04658.13 KFH45013.1 - 2.9e-51 173.4 0.1 2.9e-51 173.4 0.1 1.9 3 0 0 3 3 3 1 TAFII55 protein conserved region BUD22 PF09073.10 KFH45013.1 - 0.0029 17.0 20.4 0.0029 17.0 20.4 2.2 2 0 0 2 2 2 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 KFH45013.1 - 0.012 15.9 10.3 0.012 15.9 10.3 3.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 KFH45013.1 - 0.41 10.5 14.8 1.8 8.4 4.4 3.1 3 0 0 3 3 3 0 Myc amino-terminal region LAMTOR PF15454.6 KFH45013.1 - 4.3 8.0 10.0 4.7 7.9 0.9 2.7 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator NOA36 PF06524.12 KFH45013.1 - 4.4 6.5 33.5 0.17 11.2 7.1 3.4 3 0 0 3 3 3 0 NOA36 protein IU_nuc_hydro PF01156.19 KFH45014.1 - 5.3e-79 266.0 0.0 6.1e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MBOAT_2 PF13813.6 KFH45015.1 - 9.1e-15 54.7 6.2 2.3e-14 53.4 6.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family EzrA PF06160.12 KFH45016.1 - 0.014 13.6 6.3 0.025 12.8 6.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 KFH45016.1 - 1.5 9.0 22.5 0.023 14.9 10.5 3.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DEAD PF00270.29 KFH45017.1 - 5.6e-50 169.5 0.0 7.6e-49 165.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH45017.1 - 2.1e-27 95.7 0.0 6.8e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFH45017.1 - 0.13 11.6 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit FYDLN_acid PF09538.10 KFH45018.1 - 0.9 10.2 8.5 4.1 8.1 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ndc1_Nup PF09531.10 KFH45018.1 - 4.7 5.8 7.9 6.2 5.4 7.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WRNPLPNID PF15017.6 KFH45018.1 - 8.2 7.4 10.6 1.3 10.0 5.8 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box AAA_2 PF07724.14 KFH45019.1 - 1.9e-44 151.8 0.2 2.8e-43 148.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFH45019.1 - 5.4e-36 122.7 2.0 5.4e-36 122.7 2.0 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KFH45019.1 - 7.6e-25 86.8 0.2 7.6e-25 86.8 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFH45019.1 - 9.5e-19 68.1 0.0 2.2e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFH45019.1 - 2.7e-13 50.1 0.3 4.6e-09 36.4 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFH45019.1 - 3.4e-10 40.6 3.0 0.001 19.5 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KFH45019.1 - 1.5e-07 31.7 3.0 0.027 14.7 0.0 3.7 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KFH45019.1 - 2.7e-07 30.5 0.2 0.00039 20.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KFH45019.1 - 4.1e-06 26.8 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 KFH45019.1 - 1.2e-05 24.8 0.1 0.0086 15.5 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 KFH45019.1 - 1.8e-05 24.8 0.0 0.31 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFH45019.1 - 4.1e-05 23.2 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KFH45019.1 - 6.3e-05 23.0 7.4 0.28 11.1 0.5 4.4 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFH45019.1 - 6.4e-05 22.8 0.2 0.21 11.3 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFH45019.1 - 0.0022 18.6 4.3 0.092 13.3 0.0 3.8 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 KFH45019.1 - 0.0036 17.8 0.9 1.2 9.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 KFH45019.1 - 0.0038 17.6 0.0 0.52 10.7 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFH45019.1 - 0.0044 16.8 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH45019.1 - 0.0045 17.3 0.1 6.3 7.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain Mg_chelatase PF01078.21 KFH45019.1 - 0.0046 16.4 0.0 1.9 7.8 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 KFH45019.1 - 0.006 16.8 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KFH45019.1 - 0.0068 16.4 0.0 4.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KFH45019.1 - 0.007 16.3 1.3 1.5 8.7 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase ERM PF00769.19 KFH45019.1 - 0.0071 16.2 11.1 0.013 15.3 11.1 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SRP54 PF00448.22 KFH45019.1 - 0.0072 16.0 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KFH45019.1 - 0.0077 16.0 0.0 0.55 9.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 KFH45019.1 - 0.013 15.5 0.4 15 5.6 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFH45019.1 - 0.015 14.9 0.1 0.35 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFH45019.1 - 0.015 14.4 0.6 0.94 8.6 0.3 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 KFH45019.1 - 0.018 14.5 0.1 0.68 9.3 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein Zeta_toxin PF06414.12 KFH45019.1 - 0.019 14.2 0.0 0.75 9.0 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin DUF1154 PF06631.11 KFH45019.1 - 0.02 14.9 3.6 0.42 10.7 3.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) AAA_33 PF13671.6 KFH45019.1 - 0.031 14.5 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFH45019.1 - 0.035 14.4 1.8 0.99 9.7 0.3 3.2 2 2 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KFH45019.1 - 0.045 13.3 3.1 0.91 9.0 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DNA_topoisoIV PF00521.20 KFH45019.1 - 0.049 12.5 4.5 0.08 11.8 4.5 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A PduV-EutP PF10662.9 KFH45019.1 - 0.071 12.9 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KFH45019.1 - 0.08 13.4 18.2 34 4.9 18.9 3.3 2 1 0 2 2 2 0 AAA domain Cob_adeno_trans PF01923.18 KFH45019.1 - 0.1 12.7 1.3 0.46 10.6 1.4 2.1 2 0 0 2 2 1 0 Cobalamin adenosyltransferase NYD-SP28 PF14772.6 KFH45019.1 - 0.11 12.5 11.8 0.3 11.1 11.8 1.8 1 0 0 1 1 1 0 Sperm tail AAA_29 PF13555.6 KFH45019.1 - 0.13 12.0 0.1 7.3 6.4 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain OEP PF02321.18 KFH45019.1 - 0.16 11.8 4.1 0.33 10.8 4.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein AAA_6 PF12774.7 KFH45019.1 - 0.18 10.7 0.0 1.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF4407 PF14362.6 KFH45019.1 - 0.25 10.7 3.0 0.42 9.9 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_15 PF13175.6 KFH45019.1 - 0.34 10.6 6.2 1.7 8.2 2.7 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KFH45019.1 - 0.47 10.2 2.1 0.9 9.3 0.0 2.4 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 KFH45019.1 - 0.71 9.6 5.0 2.9 7.6 0.0 3.5 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1640 PF07798.11 KFH45019.1 - 0.88 9.6 8.6 1.9 8.5 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Med2 PF11214.8 KFH45019.1 - 1.4 9.1 7.6 4.2 7.6 6.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 2 Fmp27 PF10344.9 KFH45019.1 - 1.4 6.9 6.9 2.1 6.3 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 GrpE PF01025.19 KFH45019.1 - 2 8.0 11.9 3.3 7.4 10.3 2.1 2 0 0 2 2 1 0 GrpE V_ATPase_I PF01496.19 KFH45019.1 - 2.9 5.7 5.2 3.9 5.3 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4061 PF13270.6 KFH45019.1 - 3.6 8.0 9.1 10 6.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) FlxA PF14282.6 KFH45019.1 - 3.6 7.6 7.6 6.7 6.8 5.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.22 KFH45019.1 - 6.6 7.0 17.4 3.4 7.9 12.9 3.0 3 1 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.6 KFH45019.1 - 8.8 6.4 8.2 16 5.5 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-oxoacid_dh PF00198.23 KFH45020.1 - 3.3e-77 259.1 0.0 4.6e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFH45020.1 - 3.1e-17 62.2 0.1 5.7e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFH45020.1 - 1.8e-12 47.4 0.4 5.1e-12 45.9 0.2 1.9 2 0 0 2 2 2 1 e3 binding domain DUF3597 PF12200.8 KFH45020.1 - 8.2 7.0 8.2 3.9 8.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Ribosomal_60s PF00428.19 KFH45021.1 - 0.19 12.4 8.7 0.29 11.7 8.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_2 PF13347.6 KFH45022.1 - 9.4e-13 47.5 12.3 9.4e-13 47.5 12.3 2.2 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KFH45022.1 - 3.9e-05 22.7 5.2 8e-05 21.7 5.2 1.4 1 0 0 1 1 1 1 MFS_1 like family CDC45 PF02724.14 KFH45022.1 - 0.0073 14.7 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Filament PF00038.21 KFH45023.1 - 0.00084 19.0 19.6 0.00084 19.0 19.6 5.3 3 1 2 5 5 5 1 Intermediate filament protein BRE1 PF08647.11 KFH45023.1 - 0.0074 16.3 5.3 0.0074 16.3 5.3 5.7 3 2 2 5 5 5 1 BRE1 E3 ubiquitin ligase CCDC92 PF14916.6 KFH45023.1 - 0.029 14.1 4.0 0.23 11.3 0.0 3.7 3 1 1 4 4 4 0 Coiled-coil domain of unknown function bZIP_2 PF07716.15 KFH45023.1 - 0.045 13.8 1.2 0.045 13.8 1.2 8.2 8 1 1 9 9 9 0 Basic region leucine zipper ZapB PF06005.12 KFH45023.1 - 0.16 12.4 0.2 0.16 12.4 0.2 7.2 6 2 2 8 8 8 0 Cell division protein ZapB NPV_P10 PF05531.12 KFH45023.1 - 1.3 9.5 9.7 13 6.3 1.4 4.3 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HOOK PF05622.12 KFH45023.1 - 2.1 6.4 66.9 0.5 8.5 26.8 4.0 2 1 1 4 4 4 0 HOOK protein DUF812 PF05667.11 KFH45023.1 - 6.6 5.5 63.2 0.71 8.7 16.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF812) DUF2408 PF10303.9 KFH45024.1 - 4.8e-39 134.0 3.0 7.7e-23 81.5 0.1 4.6 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Spc7 PF08317.11 KFH45024.1 - 0.0013 17.7 0.3 0.0026 16.7 0.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4200 PF13863.6 KFH45024.1 - 0.016 15.6 0.5 0.048 14.1 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1539 PF07560.11 KFH45024.1 - 0.064 13.3 0.3 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3336 PF11815.8 KFH45024.1 - 0.4 10.4 2.1 0.64 9.7 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3336) Snapin_Pallidin PF14712.6 KFH45024.1 - 0.72 10.3 5.6 2.2 8.7 1.2 3.4 3 1 0 3 3 3 0 Snapin/Pallidin Ino80_Iec3 PF14612.6 KFH45025.1 - 5.2e-52 177.9 1.2 7.5e-32 111.9 0.3 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling zf-CCCH_4 PF18044.1 KFH45026.1 - 1.2e-08 34.5 2.8 2.1e-08 33.8 2.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFH45026.1 - 3.5e-06 26.9 5.8 6e-06 26.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFH45026.1 - 4.9e-05 23.1 2.7 9.4e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFH45026.1 - 0.0058 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFH45026.1 - 0.024 15.1 2.4 0.04 14.4 2.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KFH45026.1 - 0.057 14.1 1.8 0.11 13.2 0.1 2.5 2 0 0 2 2 2 0 Torus domain Pkinase PF00069.25 KFH45027.1 - 3.9e-65 219.8 0.0 7.4e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45027.1 - 8.7e-44 149.7 0.0 1.5e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH45027.1 - 2.8e-05 23.1 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH45027.1 - 0.0041 16.5 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RTTN_N PF14726.6 KFH45027.1 - 2.3 9.1 4.2 2.3 9.1 0.8 2.4 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Sugar_tr PF00083.24 KFH45028.1 - 7.5e-99 331.6 22.9 8.7e-99 331.4 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45028.1 - 1.3e-24 86.9 28.4 6.9e-24 84.4 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro-kuma_activ PF09286.11 KFH45029.1 - 1.2e-16 61.3 0.0 3.5e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KFH45029.1 - 6.2e-08 32.3 0.1 1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Imm49 PF15575.6 KFH45029.1 - 0.17 11.6 0.2 0.3 10.8 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 49 Abhydrolase_1 PF00561.20 KFH45030.1 - 2e-18 67.0 0.2 5.8e-18 65.5 0.1 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH45030.1 - 1.3e-12 48.8 0.0 1.7e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH45030.1 - 3.7e-10 39.5 0.0 6.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFH45030.1 - 2.3e-06 26.6 0.0 2.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KFH45030.1 - 0.0086 16.0 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal zf-C2H2 PF00096.26 KFH45031.1 - 5.7e-06 26.5 13.9 0.067 13.7 2.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type KASH_CCD PF14662.6 KFH45031.1 - 0.0003 20.7 1.1 0.00048 20.0 1.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C2H2_aberr PF17017.5 KFH45031.1 - 0.012 15.7 1.1 0.75 9.9 0.0 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger ZapB PF06005.12 KFH45031.1 - 0.013 16.0 2.6 0.029 14.8 2.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CtIP_N PF10482.9 KFH45031.1 - 0.022 14.8 1.2 0.033 14.2 0.2 1.8 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain bZIP_1 PF00170.21 KFH45031.1 - 0.023 14.8 0.5 0.048 13.8 0.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 KFH45031.1 - 0.026 14.8 0.6 0.058 13.7 0.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family betaPIX_CC PF16523.5 KFH45031.1 - 0.029 14.2 0.2 0.052 13.4 0.2 1.4 1 0 0 1 1 1 0 betaPIX coiled coil zf-C2H2_4 PF13894.6 KFH45031.1 - 0.043 14.7 11.9 3.7 8.6 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger K-box PF01486.17 KFH45031.1 - 0.044 14.0 3.2 1.1 9.5 0.5 2.4 1 1 1 2 2 2 0 K-box region PRKG1_interact PF15898.5 KFH45031.1 - 0.051 14.5 2.6 0.084 13.8 1.9 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HAP1_N PF04849.13 KFH45031.1 - 0.062 12.5 2.8 0.11 11.7 2.8 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF3450 PF11932.8 KFH45031.1 - 0.077 12.3 2.5 0.11 11.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KFH45031.1 - 0.093 13.3 2.5 0.16 12.5 2.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KFH45031.1 - 0.11 12.3 3.7 0.26 11.1 3.5 1.7 1 1 0 1 1 1 0 Septum formation initiator WD40_alt PF14077.6 KFH45031.1 - 0.16 11.8 1.5 0.33 10.9 0.9 1.8 2 0 0 2 2 1 0 Alternative WD40 repeat motif bZIP_2 PF07716.15 KFH45031.1 - 0.3 11.2 4.6 0.13 12.4 1.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper ATG16 PF08614.11 KFH45031.1 - 0.47 10.6 8.3 0.17 12.1 5.2 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) OB_NTP_bind PF07717.16 KFH45032.1 - 3e-21 75.6 0.0 6.2e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFH45032.1 - 2.9e-17 62.9 0.0 2.9e-17 62.9 0.0 3.9 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH45032.1 - 1.3e-14 54.5 0.0 3.8e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH45032.1 - 1.7e-06 27.9 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFH45032.1 - 2.2e-05 24.7 0.0 2.2e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH45032.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFH45032.1 - 0.002 17.2 0.0 0.0052 15.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KFH45032.1 - 0.0041 16.8 2.3 0.0055 16.3 0.2 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Trypan_PARP PF05887.11 KFH45032.1 - 0.0048 16.9 14.2 0.01 15.8 14.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AAA_19 PF13245.6 KFH45032.1 - 0.031 14.6 0.1 0.08 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH45032.1 - 0.081 13.4 0.1 0.3 11.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter Thump_like PF18096.1 KFH45032.1 - 0.087 12.8 1.1 0.63 10.0 0.5 2.6 2 0 0 2 2 2 0 THUMP domain-like cobW PF02492.19 KFH45032.1 - 0.093 12.3 0.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFH45032.1 - 0.51 10.2 1.8 4.8 7.1 0.1 3.1 4 0 0 4 4 4 0 NACHT domain Sugar_tr PF00083.24 KFH45033.1 - 1.7e-57 195.3 20.5 2.1e-57 195.0 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45033.1 - 2e-19 69.8 35.5 3.6e-19 68.9 32.0 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF872 PF05915.12 KFH45033.1 - 0.054 13.7 0.0 0.21 11.8 0.0 2.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CENP-Q PF13094.6 KFH45033.1 - 0.15 12.3 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Epimerase PF01370.21 KFH45034.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KFH45036.1 - 8e-16 57.9 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4472 PF14739.6 KFH45036.1 - 0.023 15.4 0.1 0.057 14.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Zn_clus PF00172.18 KFH45036.1 - 0.083 13.0 1.3 0.17 12.0 1.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_90 PF05686.12 KFH45037.1 - 6.1e-14 51.7 0.1 2.5e-10 39.9 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 90 EzrA PF06160.12 KFH45038.1 - 0.0012 17.2 15.2 0.0026 16.0 15.2 1.5 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Macoilin PF09726.9 KFH45038.1 - 0.0018 17.0 13.5 0.0018 17.0 13.5 2.1 2 0 0 2 2 2 1 Macoilin family Spc7 PF08317.11 KFH45038.1 - 0.0029 16.5 22.3 0.0029 16.5 22.3 2.2 3 0 0 3 3 3 1 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 KFH45038.1 - 0.004 17.4 17.7 0.004 17.4 17.7 2.9 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 KFH45038.1 - 0.007 16.6 20.3 0.08 13.2 6.0 3.5 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 KFH45038.1 - 0.023 14.7 27.7 0.22 11.6 18.7 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Orbi_VP5 PF00901.17 KFH45038.1 - 0.068 11.6 2.0 0.076 11.4 0.9 1.4 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 ADIP PF11559.8 KFH45038.1 - 0.22 11.6 33.9 0.2 11.8 13.1 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KFH45038.1 - 0.27 10.7 14.6 0.56 9.7 14.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KFH45038.1 - 0.41 10.8 17.1 0.41 10.8 11.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 KFH45038.1 - 0.51 11.0 30.9 0.097 13.3 5.2 3.7 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 KFH45038.1 - 0.62 10.1 28.8 0.031 14.3 12.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KFH45038.1 - 0.87 8.9 16.7 0.5 9.7 13.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_4 PF02390.17 KFH45038.1 - 1.4 8.4 5.2 20 4.6 2.2 2.7 3 0 0 3 3 2 0 Putative methyltransferase HOOK PF05622.12 KFH45038.1 - 1.5 6.9 24.8 0.24 9.5 18.6 2.1 2 0 0 2 2 2 0 HOOK protein RasGAP_C PF03836.15 KFH45038.1 - 1.6 8.9 17.2 1.2 9.3 6.1 2.5 1 1 1 2 2 2 0 RasGAP C-terminus Allexi_40kDa PF05549.11 KFH45038.1 - 1.7 8.1 11.1 4.8 6.6 9.5 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Atg14 PF10186.9 KFH45038.1 - 2.3 7.2 25.3 25 3.8 24.8 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4763 PF15960.5 KFH45038.1 - 2.5 7.4 19.8 4.2 6.6 19.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF3450 PF11932.8 KFH45038.1 - 2.5 7.3 23.0 1.9 7.7 11.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFH45038.1 - 2.8 8.1 39.4 0.32 11.2 18.5 3.4 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KFH45038.1 - 3 8.4 22.8 0.27 11.7 5.7 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 Spectrin PF00435.21 KFH45038.1 - 3.4 8.2 22.8 13 6.3 6.3 3.3 1 1 1 2 2 2 0 Spectrin repeat DUF812 PF05667.11 KFH45038.1 - 3.6 6.3 24.6 2.9 6.7 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 KFH45038.1 - 4.4 7.8 11.4 4.9e+03 -2.0 10.9 3.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.11 KFH45038.1 - 4.5 7.1 18.6 0.77 9.6 7.8 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HemX PF04375.14 KFH45038.1 - 4.8 6.4 23.3 4.2 6.5 12.5 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Sec8_exocyst PF04048.14 KFH45038.1 - 5.6 6.9 19.6 1.6 8.6 3.7 3.5 2 1 2 4 4 3 0 Sec8 exocyst complex component specific domain DUF948 PF06103.11 KFH45038.1 - 5.9 7.2 8.4 3.4 8.0 2.9 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KFH45038.1 - 6.1 7.2 29.7 1.1 9.7 22.5 2.7 2 1 0 2 2 2 0 Fez1 AAA_13 PF13166.6 KFH45038.1 - 6.5 5.3 23.6 4.2 5.9 19.1 2.1 2 1 0 2 2 2 0 AAA domain MAD PF05557.13 KFH45038.1 - 6.9 4.9 35.7 0.057 11.8 26.8 1.9 2 1 0 2 2 1 0 Mitotic checkpoint protein TMPIT PF07851.13 KFH45038.1 - 7.3 5.7 21.3 0.65 9.2 5.3 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 KFH45038.1 - 7.9 6.5 15.4 4.9 7.2 1.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) p450 PF00067.22 KFH45040.1 - 2.6e-60 204.5 0.0 3.3e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Beta_helix PF13229.6 KFH45041.1 - 0.00032 20.6 13.9 0.026 14.4 12.6 2.2 1 1 1 2 2 2 2 Right handed beta helix region UBX PF00789.20 KFH45042.1 - 2.9e-05 24.2 0.3 7.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KFH45042.1 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 KFH45042.1 - 0.018 15.3 1.4 0.024 15.0 0.5 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFH45042.1 - 0.21 11.6 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger ArfGap PF01412.18 KFH45042.1 - 0.36 10.9 5.6 0.4 10.8 3.9 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf-C2H2_aberr PF17017.5 KFH45042.1 - 0.39 10.9 1.1 0.81 9.8 0.0 1.9 2 0 0 2 2 2 0 Aberrant zinc-finger SOBP PF15279.6 KFH45042.1 - 3.1 8.3 8.8 3.7 8.1 8.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RasGAP PF00616.19 KFH45043.1 - 1.2e-24 87.2 0.0 5.6e-17 62.1 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KFH45043.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 C2 domain Bac_luciferase PF00296.20 KFH45044.1 - 1.7e-57 195.2 1.4 2.4e-57 194.8 1.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MRP-L20 PF12824.7 KFH45045.1 - 1.1e-46 159.0 4.5 1.2e-46 158.8 4.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KFH45045.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Neugrin HTH_11 PF08279.12 KFH45045.1 - 0.11 12.4 0.0 0.43 10.5 0.0 2.0 2 1 0 2 2 2 0 HTH domain Glyco_hydro_12 PF01670.16 KFH45046.1 - 1.6e-73 247.2 4.8 1.8e-73 247.1 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 JSRP PF15312.6 KFH45046.1 - 0.21 11.5 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein FMN_dh PF01070.18 KFH45047.1 - 6e-122 407.0 0.0 6.8e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KFH45047.1 - 3.6e-05 23.3 2.2 5.8e-05 22.6 2.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFH45047.1 - 4.6e-05 22.6 1.8 0.0021 17.1 1.1 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KFH45047.1 - 0.00057 19.3 1.1 0.084 12.2 0.5 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KFH45047.1 - 0.0037 16.4 0.3 0.0054 15.9 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Mur_ligase_M PF08245.12 KFH45048.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain EzrA PF06160.12 KFH45048.1 - 0.0063 14.7 0.4 0.0096 14.1 0.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mur_ligase_C PF02875.21 KFH45048.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RasGAP_C PF03836.15 KFH45048.1 - 0.059 13.5 0.4 0.29 11.3 0.2 2.0 1 1 1 2 2 2 0 RasGAP C-terminus Vir_act_alpha_C PF10400.9 KFH45048.1 - 3.3 8.5 5.7 1.4 9.6 0.8 2.3 1 1 1 2 2 2 0 Virulence activator alpha C-term Abhydrolase_6 PF12697.7 KFH45050.1 - 4.5e-06 27.4 0.3 8.3e-06 26.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFH45050.1 - 4.3e-05 23.1 0.0 0.00054 19.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFH45050.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFH45050.1 - 0.028 13.7 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Tyr_Deacylase PF02580.16 KFH45051.1 - 2.3e-52 177.4 0.1 2.6e-52 177.2 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase zf-H2C2_2 PF13465.6 KFH45053.1 - 6.8 7.3 12.3 14 6.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 KFH45054.1 - 2.7e-06 27.5 10.7 0.00046 20.5 2.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH45054.1 - 5.1e-05 23.5 0.6 5.1e-05 23.5 0.6 4.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH45054.1 - 0.006 17.3 15.2 0.11 13.4 1.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH45054.1 - 0.01 15.8 0.9 0.01 15.8 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH45054.1 - 0.07 13.4 4.3 0.075 13.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH45054.1 - 0.071 13.5 1.6 0.071 13.5 1.6 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFH45054.1 - 0.33 11.1 2.7 16 5.7 0.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain CRAL_TRIO PF00650.20 KFH45055.1 - 8.5e-39 132.8 0.0 1.4e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH45055.1 - 1.1e-13 51.1 0.1 2.8e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFH45055.1 - 1.3e-07 31.8 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pro_isomerase PF00160.21 KFH45056.1 - 6.6e-49 166.2 0.1 9.4e-49 165.7 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KFH45056.1 - 3e-08 33.2 2.9 0.00037 20.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH45056.1 - 8e-05 22.3 0.9 0.035 13.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH45056.1 - 0.0017 18.0 0.5 0.59 9.9 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 KFH45056.1 - 0.0062 16.8 0.9 0.23 11.8 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH45056.1 - 0.011 15.8 1.6 0.014 15.5 0.7 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH45056.1 - 0.1 13.5 4.2 2.1 9.4 0.2 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFH45056.1 - 0.47 11.1 14.0 0.11 13.2 3.9 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Iso_dh PF00180.20 KFH45057.1 - 2.5e-73 247.2 0.0 3e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KFH45058.1 - 1.3e-31 109.9 34.5 2.2e-31 109.1 34.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45058.1 - 0.0012 17.9 16.4 0.0025 16.8 16.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 KFH45058.1 - 0.03 14.0 1.9 0.075 12.8 1.9 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Sec1 PF00995.23 KFH45059.1 - 1.1e-122 411.2 0.0 1.2e-122 411.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PilO PF04350.13 KFH45059.1 - 0.14 12.3 1.3 0.96 9.6 0.3 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO FCH PF00611.23 KFH45060.1 - 4.9e-24 84.4 2.0 7.9e-24 83.8 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFH45060.1 - 1.4e-19 69.7 0.3 2.1e-11 43.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFH45060.1 - 4.5e-15 55.0 0.1 6.6e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KFH45060.1 - 5.8e-15 54.9 5.2 9.3e-15 54.3 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KFH45060.1 - 0.00013 21.6 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KFH45060.1 - 0.0051 17.1 0.3 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain C1_2 PF03107.16 KFH45060.1 - 0.0092 16.3 4.8 0.016 15.5 4.8 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 KFH45060.1 - 0.035 14.2 0.0 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 SH3 domain Allexi_40kDa PF05549.11 KFH45060.1 - 0.059 12.9 0.1 0.059 12.9 0.1 2.4 3 0 0 3 3 3 0 Allexivirus 40kDa protein FYVE PF01363.21 KFH45060.1 - 0.21 11.7 3.5 0.47 10.6 3.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger ISG65-75 PF11727.8 KFH45060.1 - 1.5 8.0 14.0 1.1 8.4 1.9 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein OrfB_Zn_ribbon PF07282.11 KFH45060.1 - 2.7 8.0 5.2 11 6.1 5.2 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Not3 PF04065.15 KFH45061.1 - 7.3e-89 297.2 26.6 1.3e-88 296.3 26.6 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KFH45061.1 - 1.7e-42 144.6 5.4 4.4e-42 143.3 5.4 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 KFH45061.1 - 0.0038 17.0 2.4 0.0098 15.7 2.4 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cdc13_OB2 PF18691.1 KFH45061.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain PI3K_P85_iSH2 PF16454.5 KFH45061.1 - 1.1 8.8 20.6 0.07 12.7 4.0 2.8 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cep57_MT_bd PF06657.13 KFH45061.1 - 2.6 8.5 8.8 21 5.7 0.4 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.6 KFH45061.1 - 2.7 8.4 11.0 0.81 10.1 5.1 2.6 2 0 0 2 2 2 0 Syntaxin-like protein CorA PF01544.18 KFH45061.1 - 7.4 5.8 6.1 1.3 8.2 1.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Translin PF01997.16 KFH45062.1 - 1.7e-45 155.5 0.0 2e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Ferritin PF00210.24 KFH45062.1 - 0.054 13.4 0.1 0.8 9.6 0.2 2.2 1 1 1 2 2 2 0 Ferritin-like domain DUF5631 PF18645.1 KFH45062.1 - 0.096 13.1 0.5 12 6.3 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5631) FMO-like PF00743.19 KFH45063.1 - 1.9e-15 56.3 0.0 4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH45063.1 - 9.5e-11 41.8 0.0 6.1e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH45063.1 - 2e-09 37.1 0.0 6.6e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH45063.1 - 1.1e-07 31.4 0.0 9.2e-07 28.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH45063.1 - 5.1e-07 29.1 0.0 1.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFH45063.1 - 0.0042 17.1 0.0 2.9 7.9 0.0 3.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KFH45063.1 - 0.011 15.3 0.4 0.32 10.5 0.2 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFH45063.1 - 0.013 14.7 0.4 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KFH45063.1 - 0.13 12.9 0.1 29 5.3 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH45063.1 - 0.18 10.5 0.3 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF5127 PF17168.4 KFH45064.1 - 3.8e-74 249.3 4.4 3.8e-74 249.3 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KFH45064.1 - 4.1e-68 228.4 0.3 8.1e-68 227.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KFH45064.1 - 1.7e-62 210.8 0.4 4.7e-62 209.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KFH45064.1 - 3.6e-07 29.6 0.3 1.9e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) MFS_1 PF07690.16 KFH45066.1 - 0.015 14.2 1.9 0.023 13.6 1.9 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily MoaE PF02391.17 KFH45066.1 - 0.04 14.2 0.7 0.84 9.9 0.7 2.2 1 1 0 1 1 1 0 MoaE protein Sulfatase PF00884.23 KFH45067.1 - 4.9e-50 170.7 0.0 2.9e-48 164.9 0.0 2.4 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KFH45067.1 - 1.2e-05 25.4 0.4 0.00046 20.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFH45067.1 - 1.4e-05 24.9 0.0 0.0037 16.9 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFH45067.1 - 0.00047 19.3 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 KFH45067.1 - 0.044 12.4 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KFH45067.1 - 0.055 14.2 0.1 0.12 13.1 0.1 1.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Motile_Sperm PF00635.26 KFH45068.1 - 1.2e-17 63.7 0.0 4.5e-17 61.9 0.0 1.9 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF883 PF05957.13 KFH45068.1 - 0.062 13.9 0.3 0.099 13.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Amidohydro_1 PF01979.20 KFH45068.1 - 0.075 12.3 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase family ASH PF15780.5 KFH45068.1 - 0.091 13.0 0.1 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Tmemb_55A PF09788.9 KFH45068.1 - 0.63 9.1 2.2 1.2 8.2 2.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A Cu-oxidase_3 PF07732.15 KFH45069.1 - 5.4e-41 139.3 0.2 2.2e-40 137.4 0.2 2.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFH45069.1 - 4.8e-31 107.3 6.7 3e-25 88.5 0.3 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KFH45069.1 - 8.6e-13 48.7 0.0 7.7e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase 7tm_2 PF00002.24 KFH45070.1 - 1.8e-07 30.7 12.2 3.3e-07 29.9 12.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KFH45070.1 - 1e-06 28.2 3.1 2.4e-06 26.9 3.1 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF4748 PF15932.5 KFH45070.1 - 1 9.1 4.1 2.6 7.9 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) tRNA-synt_1b PF00579.25 KFH45071.1 - 1.4e-57 195.2 0.0 1.9e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Globin PF00042.22 KFH45072.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 KFH45072.1 - 1.1e-05 26.0 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFH45072.1 - 0.00012 22.4 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFH45072.1 - 0.012 15.7 0.0 0.51 10.5 0.0 2.8 3 0 0 3 3 3 0 Ferric reductase NAD binding domain HTH_OrfB_IS605 PF12323.8 KFH45073.1 - 0.074 12.6 0.4 0.074 12.6 0.4 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF308 PF03729.13 KFH45073.1 - 1.4 9.3 7.6 0.72 10.2 3.0 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) zf-LITAF-like PF10601.9 KFH45074.1 - 8.6e-08 32.3 1.6 1.6e-07 31.5 1.6 1.5 1 1 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ISL3 PF14690.6 KFH45074.1 - 0.00078 20.1 1.0 1 10.1 0.1 2.2 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 LBP_C PF17386.2 KFH45074.1 - 0.045 13.7 0.4 0.83 9.6 0.0 2.7 3 0 0 3 3 3 0 Lacto-N-biose phosphorylase C-terminal domain Sgf11 PF08209.11 KFH45074.1 - 0.052 13.1 1.8 0.15 11.7 0.2 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Terminase_GpA PF05876.12 KFH45074.1 - 0.06 11.9 0.4 0.065 11.8 0.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1 PF03811.13 KFH45074.1 - 0.063 13.0 0.9 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 InsA N-terminal domain HypA PF01155.19 KFH45074.1 - 0.084 12.9 0.2 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3797 PF12677.7 KFH45074.1 - 0.096 12.6 0.1 0.096 12.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 KFH45074.1 - 0.17 11.4 3.0 0.31 10.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.7 KFH45075.1 - 1.3e-83 275.6 7.2 2.6e-17 63.2 0.2 9.8 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH45075.1 - 1.1e-71 236.4 13.1 1e-09 38.7 0.0 14.1 8 2 8 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KFH45075.1 - 1.2e-65 215.3 20.2 4.3e-06 26.9 0.3 15.5 14 1 1 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 KFH45075.1 - 1.8e-54 181.1 19.1 6.2e-08 32.8 0.1 12.2 6 4 7 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH45075.1 - 8.1e-46 148.7 6.7 0.0013 19.0 0.1 17.1 19 0 0 19 19 19 10 Ankyrin repeat CorA PF01544.18 KFH45075.1 - 5.3e-10 39.1 3.9 1.3e-09 37.9 3.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Nitro_FeMo-Co PF02579.17 KFH45075.1 - 0.051 13.9 0.0 62 4.0 0.0 3.5 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF4618 PF15397.6 KFH45075.1 - 0.064 12.7 0.3 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FA_desaturase PF00487.24 KFH45076.1 - 2.3e-25 89.9 15.8 2.3e-25 89.9 15.8 1.6 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KFH45076.1 - 3.7e-19 67.9 0.2 7.7e-19 66.9 0.2 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 KFH45077.1 - 6.5e-13 48.6 0.0 1.6e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45077.1 - 1.4e-09 37.6 0.0 7.3e-06 25.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DnaJ_C PF01556.18 KFH45078.1 - 8e-30 103.9 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFH45078.1 - 4.9e-26 90.6 1.5 8.1e-26 89.9 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFH45078.1 - 5.3e-15 55.5 15.4 8.2e-15 54.9 15.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFH45078.1 - 0.0003 20.7 8.3 0.045 13.7 0.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 KFH45078.1 - 0.00041 20.7 7.4 0.35 11.3 0.0 4.1 3 1 1 4 4 4 2 Restriction alleviation protein Lar HypA PF01155.19 KFH45078.1 - 0.0033 17.4 4.6 0.56 10.2 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KFH45078.1 - 0.99 9.0 6.1 0.48 10.1 0.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 AMP-binding PF00501.28 KFH45079.1 - 1.5e-87 294.0 0.0 1.8e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH45079.1 - 3e-17 63.4 0.1 1.3e-16 61.3 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KFH45079.1 - 0.00017 20.6 0.0 0.0049 15.8 0.0 2.4 2 1 1 3 3 3 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KFH45079.1 - 0.003 17.7 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 RTX C-terminal domain DUF4286 PF14114.6 KFH45080.1 - 0.0083 16.6 0.1 3.2 8.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Mvb12 PF09452.10 KFH45080.1 - 0.041 14.3 0.1 0.42 11.1 0.1 2.2 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 EthD PF07110.11 KFH45080.1 - 0.16 13.1 0.1 31 5.8 0.0 2.4 2 1 0 2 2 2 0 EthD domain Ribosomal_60s PF00428.19 KFH45081.1 - 7.4e-26 90.6 6.9 8.8e-26 90.3 6.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FYVE PF01363.21 KFH45082.1 - 0.013 15.6 5.2 0.013 15.6 5.2 2.7 3 1 0 3 3 3 0 FYVE zinc finger MFMR_assoc PF16596.5 KFH45083.1 - 0.071 13.6 4.7 0.17 12.3 4.7 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR tRNA_anti-like PF12869.7 KFH45083.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like ODV-E18 PF10717.9 KFH45083.1 - 0.21 11.5 0.9 1.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Alpha_GJ PF03229.13 KFH45083.1 - 5.9 7.5 8.4 0.53 10.8 1.4 2.3 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF218 PF02698.17 KFH45084.1 - 4.4e-09 36.5 0.0 5.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain MFS_1 PF07690.16 KFH45085.1 - 2.2e-09 36.7 32.3 3.9e-09 35.9 31.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFH45085.1 - 1.4e-05 24.8 3.9 1.4e-05 24.8 3.9 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Glyco_hydro_43 PF04616.14 KFH45088.1 - 1.2e-46 159.4 4.7 1.5e-46 159.1 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KFH45088.1 - 1.3e-40 138.5 0.9 2.6e-40 137.6 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KFH45088.1 - 5.2e-08 33.0 0.1 1.2e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KFH45088.1 - 0.13 11.8 2.4 0.31 10.6 2.4 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain ICE2 PF08426.10 KFH45089.1 - 2.4e-158 527.5 9.3 2.7e-158 527.4 9.3 1.0 1 0 0 1 1 1 1 ICE2 Fungal_trans_2 PF11951.8 KFH45090.1 - 2.6e-25 89.0 0.1 3.6e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45090.1 - 5.7e-06 26.3 8.1 8.4e-06 25.8 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 KFH45091.1 - 8.4e-105 350.9 0.0 9.7e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III RisS_PPD PF16524.5 KFH45091.1 - 0.2 11.9 0.1 0.44 10.8 0.1 1.5 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS YCII PF03795.14 KFH45094.1 - 4.2e-08 33.5 0.0 6.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Cyclin PF08613.11 KFH45095.1 - 8.2e-40 136.8 0.0 2.2e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KFH45095.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SR-25 PF10500.9 KFH45095.1 - 0.22 11.1 7.4 0.33 10.5 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 KFH45095.1 - 2.2 8.1 11.6 3.4 7.5 11.6 1.3 1 0 0 1 1 1 0 SPX domain Dehydrin PF00257.19 KFH45095.1 - 9.4 6.8 10.0 2.2 8.8 0.9 2.4 2 0 0 2 2 2 0 Dehydrin NUDE_C PF04880.13 KFH45096.1 - 4.6e-39 134.7 10.9 4.6e-39 134.7 10.9 4.5 2 1 2 4 4 1 1 NUDE protein, C-terminal conserved region Tho2 PF11262.8 KFH45096.1 - 0.0026 17.0 4.8 0.0026 17.0 4.8 2.2 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 DUF1729 PF08354.10 KFH45096.1 - 0.037 12.9 0.4 0.056 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Atg14 PF10186.9 KFH45096.1 - 0.38 9.8 28.6 1.8e+02 1.0 0.0 3.1 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KFH45096.1 - 0.68 10.4 30.7 1.9 8.9 18.3 3.1 2 1 1 3 3 3 0 Fez1 Filament PF00038.21 KFH45096.1 - 0.72 9.4 34.9 1.1 8.7 14.6 2.7 2 1 1 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFH45096.1 - 0.76 9.8 36.3 4.5 7.3 14.0 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KFH45096.1 - 1.2 8.9 36.0 0.74 9.6 26.3 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Fmp27_WPPW PF10359.9 KFH45096.1 - 1.5 7.6 18.9 0.04 12.8 8.8 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Chibby PF14645.6 KFH45096.1 - 1.8 9.0 10.5 3.6 8.0 2.0 2.6 1 1 1 2 2 2 0 Chibby family Tropomyosin_1 PF12718.7 KFH45096.1 - 2.9 8.1 36.0 21 5.2 20.6 3.5 2 1 1 3 3 3 0 Tropomyosin like DUF745 PF05335.13 KFH45096.1 - 3 7.5 18.0 0.041 13.6 8.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PSII_Pbs27 PF13326.6 KFH45096.1 - 5 7.4 11.7 0.52 10.6 5.1 2.2 1 1 1 2 2 2 0 Photosystem II Pbs27 FAD_binding_4 PF01565.23 KFH45097.1 - 1.1e-30 106.2 0.5 1.9e-30 105.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH45097.1 - 2.5e-12 46.7 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like HtaA PF04213.13 KFH45098.1 - 0.023 15.2 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Htaa AA_permease PF00324.21 KFH45099.1 - 3.8e-109 365.4 40.5 8e-109 364.4 40.5 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH45099.1 - 4.4e-19 68.6 39.1 5.8e-19 68.2 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.21 KFH45100.1 - 3.9e-65 219.9 0.0 4.8e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family KORA PF16509.5 KFH45100.1 - 0.025 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor AMP-binding PF00501.28 KFH45101.1 - 2.4e-62 210.9 0.0 2.5e-61 207.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH45101.1 - 8.4e-12 45.9 0.2 2.4e-11 44.4 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SUIM_assoc PF16619.5 KFH45101.1 - 4.9 7.3 6.1 12 6.0 6.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ketoacyl-synt PF00109.26 KFH45102.1 - 2.5e-70 236.9 0.0 5.3e-70 235.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH45102.1 - 1.1e-62 211.2 0.0 2.7e-62 209.9 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH45102.1 - 5.7e-52 176.8 0.0 1e-51 176.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH45102.1 - 3.1e-44 151.8 0.0 6.2e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH45102.1 - 1.7e-39 134.5 1.1 4.4e-39 133.1 0.5 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFH45102.1 - 1.1e-19 71.8 0.0 1.7e-18 68.0 0.1 2.9 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFH45102.1 - 1.9e-17 63.8 0.0 4.5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KFH45102.1 - 9.4e-16 58.0 2.3 1.3e-15 57.5 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KFH45102.1 - 9.9e-16 58.2 0.0 2.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFH45102.1 - 8.3e-12 45.0 0.0 2.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFH45102.1 - 5.5e-10 39.8 0.0 2.9e-09 37.5 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH45102.1 - 1.6e-09 37.8 0.0 4.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFH45102.1 - 6.9e-09 35.9 0.1 9.6e-08 32.3 0.0 2.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KFH45102.1 - 3.2e-08 33.5 0.0 9.1e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH45102.1 - 1.9e-07 30.9 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KFH45102.1 - 2e-07 31.5 0.0 5.6e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KFH45102.1 - 0.00033 20.5 0.5 0.00073 19.3 0.5 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KFH45102.1 - 0.0017 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KFH45102.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KFH45102.1 - 0.052 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase ACC_central PF08326.12 KFH45103.1 - 1.3e-276 919.6 0.0 1.2e-275 916.5 0.0 1.9 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KFH45103.1 - 1.8e-183 610.7 0.0 2.4e-183 610.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFH45103.1 - 3.4e-52 177.0 0.0 6.4e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFH45103.1 - 1.3e-27 96.5 0.1 2.6e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFH45103.1 - 1.3e-23 83.1 0.0 6.3e-20 71.3 0.0 3.6 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFH45103.1 - 8.6e-16 57.5 0.1 2.1e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KFH45103.1 - 0.0073 16.5 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp_3 PF02655.14 KFH45103.1 - 0.0077 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFH45103.1 - 0.0098 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KFH45103.1 - 0.012 15.4 0.0 0.058 13.2 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KFH45103.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KFH45103.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ABC_tran PF00005.27 KFH45104.1 - 1.3e-42 145.5 0.0 8.7e-28 97.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFH45104.1 - 1e-25 90.9 7.4 1.6e-18 67.3 4.0 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KFH45104.1 - 1.1e-12 47.9 0.1 0.00031 20.2 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH45104.1 - 3.4e-06 26.7 0.5 0.016 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH45104.1 - 1.4e-05 25.5 0.2 0.3 11.4 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KFH45104.1 - 1.5e-05 24.9 0.5 0.058 13.2 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFH45104.1 - 9.6e-05 23.0 0.1 0.63 10.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KFH45104.1 - 0.00028 21.0 0.0 1.5 9.2 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KFH45104.1 - 0.00033 20.6 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFH45104.1 - 0.0015 18.8 0.4 1.3 9.3 0.3 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFH45104.1 - 0.0017 18.4 0.1 0.12 12.5 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KFH45104.1 - 0.0048 16.3 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KFH45104.1 - 0.0062 16.6 0.3 0.15 12.1 0.1 2.3 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 KFH45104.1 - 0.0068 16.5 0.5 0.014 15.5 0.5 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 KFH45104.1 - 0.016 14.3 0.4 2.6 7.0 0.4 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KFH45104.1 - 0.022 14.5 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFH45104.1 - 0.089 12.0 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KFH45104.1 - 0.099 12.2 0.1 3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFH45104.1 - 0.13 11.9 0.7 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 KFH45104.1 - 0.16 11.7 0.1 40 3.9 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AIG1 PF04548.16 KFH45104.1 - 0.24 10.7 0.7 1.5 8.1 0.4 2.4 3 0 0 3 3 3 0 AIG1 family NACHT PF05729.12 KFH45104.1 - 0.7 9.8 2.4 16 5.4 0.1 3.0 3 0 0 3 3 3 0 NACHT domain DUF4131 PF13567.6 KFH45104.1 - 9 5.9 15.8 1.3 8.7 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Aminotran_3 PF00202.21 KFH45105.1 - 2.5e-81 273.4 0.1 3e-81 273.1 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_43 PF04616.14 KFH45106.1 - 2.2e-59 201.2 11.9 8.5e-52 176.2 6.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFH45106.1 - 5.2e-06 26.3 0.6 0.026 14.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain DUF842 PF05811.13 KFH45107.1 - 0.096 12.4 11.2 0.24 11.1 0.0 4.3 2 2 3 5 5 5 0 Eukaryotic protein of unknown function (DUF842) ComFB PF10719.9 KFH45107.1 - 0.18 12.0 6.2 4.9 7.3 0.1 4.5 2 1 1 3 3 3 0 Late competence development protein ComFB Apolipoprotein PF01442.18 KFH45107.1 - 5 6.9 67.5 12 5.7 0.3 6.4 3 1 2 5 5 5 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KFH45107.1 - 6.6 6.9 6.8 9.2 6.4 2.2 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Pyr_redox_2 PF07992.14 KFH45108.1 - 1.3e-13 50.8 0.0 6.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFH45108.1 - 1.6e-12 46.6 0.0 8.4e-06 24.5 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFH45108.1 - 2.3e-11 43.5 0.0 4.5e-10 39.3 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH45108.1 - 7.5e-08 32.5 1.1 5.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH45108.1 - 1.5e-06 28.7 2.8 0.041 14.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH45108.1 - 1.5e-06 28.1 0.0 4.4e-06 26.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFH45108.1 - 1.7e-06 27.5 0.0 0.00015 21.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KFH45108.1 - 0.00011 21.5 2.2 0.011 15.0 0.7 2.1 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFH45108.1 - 0.0017 18.4 2.6 0.021 14.8 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KFH45108.1 - 0.0038 17.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFH45108.1 - 0.0049 16.8 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFH45108.1 - 0.03 13.4 1.0 0.058 12.5 1.0 1.5 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFH45108.1 - 0.04 13.3 0.1 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KFH45108.1 - 0.15 10.7 3.2 0.098 11.3 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KFH45108.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFH45108.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KFH45108.1 - 0.26 10.3 1.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A G-alpha PF00503.20 KFH45109.1 - 1.9e-25 89.8 0.0 7.8e-25 87.8 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit RINGv PF12906.7 KFH45111.1 - 1.8e-15 56.8 8.2 3.1e-15 56.0 8.2 1.4 1 0 0 1 1 1 1 RING-variant domain Baculo_11_kDa PF06143.11 KFH45111.1 - 0.0057 16.2 3.7 0.093 12.3 1.9 2.6 2 0 0 2 2 2 1 Baculovirus 11 kDa family zf-RING_2 PF13639.6 KFH45111.1 - 0.016 15.6 8.8 0.027 14.8 8.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KFH45111.1 - 0.1 12.6 3.0 0.26 11.4 3.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TRI12 PF06609.13 KFH45113.1 - 3.2e-53 181.1 21.5 3.9e-53 180.8 21.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH45113.1 - 4.6e-20 71.8 47.5 4.6e-20 71.8 47.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45113.1 - 3.3e-09 36.1 1.4 3.3e-09 36.1 1.4 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter GMC_oxred_N PF00732.19 KFH45115.1 - 5.6e-45 154.0 0.0 1.1e-43 149.8 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH45115.1 - 2.6e-34 118.8 0.0 4.7e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFH45115.1 - 5.6e-05 23.3 0.5 0.00017 21.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH45115.1 - 0.00096 18.3 0.3 0.032 13.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KFH45115.1 - 0.009 15.6 0.7 0.028 14.0 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 KFH45115.1 - 0.0095 14.5 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 KFH45115.1 - 0.052 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFH45115.1 - 0.19 10.9 0.2 0.32 10.2 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KFH45115.1 - 0.2 10.9 0.1 0.33 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BolA PF01722.18 KFH45116.1 - 1.4e-09 38.1 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein p450 PF00067.22 KFH45117.1 - 1.6e-17 63.4 1.9 1.5e-11 43.8 0.0 2.5 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_64 PF16483.5 KFH45118.1 - 1.1e-93 314.5 0.0 1.2e-93 314.3 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase adh_short PF00106.25 KFH45119.1 - 1.6e-26 93.0 1.1 4.2e-25 88.4 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45119.1 - 3.8e-23 82.3 0.9 4.3e-22 78.8 0.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH45119.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH45119.1 - 0.00027 20.0 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KFH45119.1 - 0.035 14.0 0.7 0.13 12.2 0.2 2.1 2 1 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KFH45119.1 - 0.04 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CDH-cyt PF16010.5 KFH45120.1 - 8.5e-46 155.9 0.2 1e-45 155.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase TPP_enzyme_N PF02776.18 KFH45121.1 - 8.2e-40 136.2 0.0 1.6e-38 132.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFH45121.1 - 1.2e-21 77.0 0.0 2.9e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFH45121.1 - 6.3e-11 42.2 0.0 5.3e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 KFH45121.1 - 0.0045 17.3 0.5 0.17 12.3 0.2 3.2 2 1 0 2 2 2 1 MobA-like NTP transferase domain DHHC PF01529.20 KFH45122.1 - 2.4e-31 108.6 16.9 2.4e-31 108.6 16.9 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KFH45122.1 - 3.5e-28 98.0 0.0 5.3e-14 52.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH45122.1 - 4.6e-24 84.5 0.8 1.9e-06 28.3 0.2 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH45122.1 - 5.7e-22 77.5 0.3 1.7e-05 25.0 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH45122.1 - 7.8e-22 75.0 1.0 2.1e-07 30.7 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KFH45122.1 - 8.8e-22 76.5 0.5 1.3e-05 25.4 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat AMP-binding PF00501.28 KFH45123.1 - 0 1391.7 0.0 1.4e-77 261.1 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KFH45123.1 - 3.5e-266 883.1 0.0 4e-44 151.0 0.0 10.5 8 3 2 10 10 10 10 Condensation domain PP-binding PF00550.25 KFH45123.1 - 2.6e-77 255.1 5.4 4.3e-13 49.4 0.0 7.2 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH45123.1 - 1.8e-26 92.9 8.1 0.066 14.2 0.0 9.0 8 0 0 8 8 8 7 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KFH45123.1 - 4.6e-14 52.9 0.0 1.4e-05 25.7 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45123.1 - 6.8e-09 35.7 0.0 0.00057 19.7 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_9 PF08003.11 KFH45123.1 - 0.004 16.1 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KFH45123.1 - 0.18 11.5 0.0 24 4.6 0.0 2.4 2 0 0 2 2 2 0 Lysine methyltransferase AATase PF07247.12 KFH45123.1 - 0.47 9.0 4.1 4.8 5.6 0.0 3.3 5 0 0 5 5 5 0 Alcohol acetyltransferase MHYT PF03707.16 KFH45124.1 - 9.5e-19 67.3 23.0 8.8e-12 45.0 1.1 4.7 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Peptidase_U4 PF03419.13 KFH45124.1 - 2.7 7.2 20.3 0.35 10.1 12.6 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA p450 PF00067.22 KFH45125.1 - 2.2e-24 86.0 0.0 4.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.16 KFH45126.1 - 6.8e-05 22.9 0.0 0.0072 16.4 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SRPRB PF09439.10 KFH45127.1 - 1.4e-27 96.3 0.0 2.5e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFH45127.1 - 1.1e-06 28.2 0.0 1.3e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH45127.1 - 8.6e-06 25.8 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH45127.1 - 6.3e-05 22.6 0.2 0.00013 21.6 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFH45127.1 - 0.00071 20.0 0.3 0.0015 19.0 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KFH45127.1 - 0.0017 18.6 0.0 0.011 15.9 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFH45127.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Septin cobW PF02492.19 KFH45127.1 - 0.0081 15.8 0.3 2.9 7.5 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 KFH45127.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFH45127.1 - 0.02 14.8 1.6 0.87 9.5 0.9 2.4 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFH45127.1 - 0.038 14.5 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 KFH45127.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 Ras family SRP54 PF00448.22 KFH45127.1 - 0.1 12.2 0.5 9.7 5.8 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Amidohydro_2 PF04909.14 KFH45128.1 - 2.4e-20 73.5 0.1 3.3e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.28 KFH45129.1 - 4.9e-229 760.1 0.0 2.9e-82 276.5 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFH45129.1 - 2.6e-138 461.5 0.0 7.1e-41 140.3 0.0 6.0 5 2 0 5 5 5 4 Condensation domain PP-binding PF00550.25 KFH45129.1 - 1.3e-36 124.7 4.8 1.6e-11 44.4 0.1 5.7 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH45129.1 - 5.3e-06 27.3 0.0 0.16 13.0 0.0 3.7 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain HTH_Tnp_1 PF01527.20 KFH45129.1 - 0.027 14.8 0.5 5 7.5 0.0 3.4 3 0 0 3 3 3 0 Transposase Transferase PF02458.15 KFH45129.1 - 0.079 11.6 0.0 5.3 5.6 0.0 3.0 3 0 0 3 3 3 0 Transferase family EphA2_TM PF14575.6 KFH45130.1 - 0.0095 16.8 0.0 0.012 16.5 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF456 PF04306.13 KFH45130.1 - 0.072 13.4 0.0 0.099 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) STE2 PF02116.15 KFH45130.1 - 0.091 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Rick_17kDa_Anti PF05433.15 KFH45130.1 - 0.11 12.4 1.3 0.18 11.7 1.3 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KFH45130.1 - 0.13 12.0 1.5 0.21 11.4 1.5 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Mid2 PF04478.12 KFH45130.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Dabb PF07876.12 KFH45131.1 - 4.2e-08 33.7 0.0 4.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PALP PF00291.25 KFH45133.1 - 3.2e-65 220.5 0.1 6.2e-65 219.5 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFH45133.1 - 1e-13 51.5 0.0 2.9e-08 34.0 0.0 3.0 2 0 0 2 2 2 2 CBS domain Peptidase_M28 PF04389.17 KFH45134.1 - 2.1e-43 148.3 0.1 3.1e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH45134.1 - 8.3e-11 41.8 0.2 3.9e-10 39.6 0.1 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KFH45134.1 - 1.8e-05 24.5 0.0 4.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 KFH45134.1 - 0.0017 17.3 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4910) YebO PF13974.6 KFH45136.1 - 0.15 12.1 0.8 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 YebO-like protein p450 PF00067.22 KFH45139.1 - 3.6e-26 91.9 0.6 5e-26 91.5 0.6 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_24 PF13578.6 KFH45139.1 - 0.091 13.8 1.2 7.2 7.7 0.1 3.2 3 1 0 3 3 3 0 Methyltransferase domain EAP30 PF04157.16 KFH45140.1 - 4.8e-41 140.6 0.1 6.3e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KFH45140.1 - 2.6e-23 82.0 0.0 4.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KFH45140.1 - 5.4e-23 80.2 2.3 5.4e-23 80.2 2.3 2.8 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KFH45140.1 - 0.00037 19.8 1.0 0.00037 19.8 1.0 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KFH45140.1 - 0.0044 17.0 5.3 0.037 14.1 0.2 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 KFH45140.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.7 KFH45140.1 - 0.23 11.5 4.6 0.11 12.5 0.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 KFH45140.1 - 0.35 10.8 1.7 0.82 9.6 1.7 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C2H2_4 PF13894.6 KFH45140.1 - 9.9 7.3 8.1 21 6.3 0.6 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger IBN_N PF03810.19 KFH45141.1 - 1.9e-13 50.1 0.5 8.2e-13 48.1 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFH45141.1 - 0.0051 16.9 0.0 0.036 14.1 0.0 2.5 2 1 0 2 2 2 1 Exportin 1-like protein Methyltransf_25 PF13649.6 KFH45142.1 - 2.2e-16 60.4 0.2 9.3e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH45142.1 - 2.3e-16 60.2 0.1 4.4e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH45142.1 - 4.6e-12 46.1 0.0 5.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45142.1 - 2.5e-10 40.3 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH45142.1 - 9.1e-09 36.0 0.1 1.6e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFH45142.1 - 7.4e-07 28.8 0.2 9.9e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFH45142.1 - 1.4e-06 27.8 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 KFH45142.1 - 6.4e-05 22.9 0.7 0.00041 20.3 0.5 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase MTS PF05175.14 KFH45142.1 - 0.00012 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KFH45142.1 - 0.00055 19.6 0.0 0.00078 19.1 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KFH45142.1 - 0.0034 17.2 0.1 0.0039 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 KFH45142.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KFH45142.1 - 0.04 13.2 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KFH45142.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase AdoMet_MTase PF07757.13 KFH45142.1 - 0.075 13.4 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase HAD PF12710.7 KFH45143.1 - 2.5e-23 83.5 0.0 3.1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFH45143.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KFH45143.1 - 0.0085 16.4 0.1 0.12 12.6 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFH45143.1 - 0.015 14.7 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase ATP19 PF11022.8 KFH45144.1 - 3.2e-27 94.7 0.0 3.9e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DUF1304 PF06993.12 KFH45144.1 - 0.13 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) eIF-1a PF01176.19 KFH45145.1 - 4.7e-16 58.4 0.0 6.4e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MFS_1 PF07690.16 KFH45146.1 - 6.5e-42 143.7 45.5 5.2e-38 130.9 44.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45146.1 - 1.7e-15 56.8 8.2 1.7e-15 56.8 8.2 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KFH45146.1 - 3.3e-15 55.6 25.8 4.6e-15 55.1 25.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DAO PF01266.24 KFH45148.1 - 8.6e-35 120.9 4.3 9.9e-35 120.7 4.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH45148.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH45148.1 - 0.004 17.4 0.2 0.0096 16.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH45148.1 - 0.022 14.0 0.4 0.022 14.0 0.4 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KFH45148.1 - 0.049 12.8 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH45148.1 - 0.12 13.0 0.2 0.3 11.7 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH45148.1 - 0.25 10.5 2.1 0.22 10.7 0.7 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KFH45148.1 - 0.27 10.3 0.5 0.4 9.7 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PDDEXK_1 PF12705.7 KFH45149.1 - 0.046 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Glyco_hydro_31 PF01055.26 KFH45150.1 - 6.8e-97 325.4 7.8 1.1e-96 324.8 7.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFH45150.1 - 0.045 14.1 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Bap31_Bap29_C PF18035.1 KFH45151.1 - 0.046 13.7 0.5 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CBFB_NFYA PF02045.15 KFH45151.1 - 0.071 13.8 2.3 0.22 12.1 2.3 1.8 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Sas10_Utp3 PF04000.15 KFH45152.1 - 1.9e-18 66.8 1.0 5.4e-18 65.4 1.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Dcc1 PF09724.9 KFH45154.1 - 4.9e-12 45.8 0.1 5.5e-12 45.6 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF4147 PF13660.6 KFH45154.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Minor_tail_Z PF06763.11 KFH45156.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) FAM86 PF14904.6 KFH45156.1 - 0.19 11.8 1.3 0.52 10.4 0.6 1.9 1 1 1 2 2 2 0 Family of unknown function RhoGEF PF00621.20 KFH45157.1 - 2.4e-26 93.1 0.0 5.1e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KFH45157.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) ING PF12998.7 KFH45157.1 - 3.1 8.4 6.1 15 6.2 0.6 3.5 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Seryl_tRNA_N PF02403.22 KFH45157.1 - 8.4 6.7 15.7 0.93 9.8 7.6 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RTA1 PF04479.13 KFH45159.1 - 1.5e-69 233.8 1.1 1.9e-69 233.4 1.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF218 PF02698.17 KFH45160.1 - 3.4e-14 53.0 0.0 7.4e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 DUF218 domain Sin_N PF04801.13 KFH45161.1 - 7.5e-21 74.8 0.0 3.8e-20 72.5 0.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region Fungal_trans_2 PF11951.8 KFH45162.1 - 2e-30 105.9 0.1 2.7e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45162.1 - 9.9e-06 25.6 9.2 1.6e-05 24.9 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AKAP2_C PF15304.6 KFH45162.1 - 0.73 9.1 5.9 1.1 8.5 5.9 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Rho_GDI PF02115.17 KFH45163.1 - 2.3e-67 226.6 0.5 2.6e-67 226.4 0.5 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_S16 PF00886.19 KFH45163.1 - 0.12 12.4 0.1 0.37 10.9 0.1 1.8 1 1 0 1 1 1 0 Ribosomal protein S16 NAD_binding_2 PF03446.15 KFH45165.1 - 1e-38 133.0 0.1 1.5e-38 132.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFH45165.1 - 3.6e-29 101.5 0.0 7.2e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFH45165.1 - 1.6e-06 28.6 0.0 6e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 KFH45165.1 - 0.00026 21.1 0.0 0.00071 19.7 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KFH45165.1 - 0.00048 19.2 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.18 KFH45165.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 KFH45165.1 - 0.015 16.1 0.0 0.043 14.7 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 KFH45165.1 - 0.015 16.0 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Ribosom_S30AE_C PF16321.5 KFH45165.1 - 0.025 14.3 0.8 0.052 13.3 0.8 1.6 1 1 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus 3HCDH_N PF02737.18 KFH45165.1 - 0.14 12.1 0.0 0.46 10.3 0.0 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KFH45167.1 - 2.1e-28 99.3 36.8 4.3e-28 98.3 36.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH45167.1 - 1.1e-11 43.9 8.8 1.1e-11 43.9 8.8 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SH3_1 PF00018.28 KFH45168.1 - 1.2e-26 92.0 0.0 1.2e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFH45168.1 - 6.1e-19 67.6 0.0 1.5e-10 40.8 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KFH45168.1 - 5.8e-14 52.0 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KFH45168.1 - 8.3e-13 47.8 0.0 7.9e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KFH45168.1 - 5.4e-07 29.5 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TFIIA PF03153.13 KFH45168.1 - 0.48 10.4 14.6 1.5 8.7 5.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KFH45168.1 - 2.4 8.8 14.3 1.2 9.8 2.5 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GST_N_2 PF13409.6 KFH45169.1 - 1.7e-18 66.7 0.2 1.5e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFH45169.1 - 3.3e-18 65.9 0.0 1.2e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH45169.1 - 5.9e-09 35.8 0.2 5.9e-09 35.8 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFH45169.1 - 1.9e-08 34.5 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFH45169.1 - 8.1e-05 22.8 0.0 0.00023 21.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH45169.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFH45169.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IBR PF01485.21 KFH45170.1 - 0.00013 22.1 5.4 0.00013 22.1 5.4 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DUF382 PF04037.13 KFH45170.1 - 0.014 15.5 0.7 0.049 13.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF382) TFIIA PF03153.13 KFH45170.1 - 0.018 15.1 21.1 0.025 14.6 21.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAT PF15234.6 KFH45170.1 - 0.086 12.6 2.6 0.22 11.2 2.6 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells Fungal_trans PF04082.18 KFH45171.1 - 1.3e-14 53.9 0.0 3e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45171.1 - 1.7e-07 31.2 7.0 2.7e-07 30.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.12 KFH45172.1 - 2.5e-60 204.3 0.0 3.6e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KFH45172.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KFH45172.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KFH45172.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFH45172.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) She9_MDM33 PF05546.11 KFH45173.1 - 8.3e-81 270.5 5.6 1.1e-80 270.1 5.6 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DUF4407 PF14362.6 KFH45173.1 - 0.026 13.9 3.0 0.056 12.8 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BCAS2 PF05700.11 KFH45173.1 - 0.17 11.5 10.1 0.36 10.5 2.3 2.6 2 1 1 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) TraC PF07820.12 KFH45173.1 - 3.3 8.1 6.2 1.1 9.6 1.8 2.4 2 1 1 3 3 3 0 TraC-like protein SAC3_GANP PF03399.16 KFH45174.1 - 1.1e-25 90.7 1.2 1.3e-23 83.9 1.2 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KFH45174.1 - 0.0012 18.8 0.2 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Cellulase PF00150.18 KFH45175.1 - 2.8e-10 40.1 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HTH_Tnp_Tc5 PF03221.16 KFH45176.1 - 5e-06 26.5 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Cep57_CLD_2 PF14197.6 KFH45176.1 - 0.11 12.6 3.7 0.092 12.8 2.1 1.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Acyl-CoA_dh_1 PF00441.24 KFH45177.1 - 1.5e-40 138.8 4.1 1.5e-40 138.8 4.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH45177.1 - 3.2e-29 101.9 0.9 1.3e-28 99.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFH45177.1 - 1.2e-21 76.7 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFH45177.1 - 2.6e-17 63.3 1.1 2.6e-17 63.3 1.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFH45177.1 - 6.6e-05 22.7 0.0 0.0002 21.1 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Zn_clus PF00172.18 KFH45178.1 - 4.8e-07 29.8 11.4 1.1e-06 28.7 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH45178.1 - 0.00068 18.7 2.8 0.0011 18.1 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSCyt2 PF07583.11 KFH45178.1 - 0.14 12.1 0.4 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Fungal_trans PF04082.18 KFH45180.1 - 1.8e-11 43.6 0.0 2.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45180.1 - 5.2e-06 26.5 6.6 1.1e-05 25.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AC_N PF16214.5 KFH45180.1 - 9.8 5.2 6.6 12 4.8 1.7 2.2 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PI31_Prot_N PF11566.8 KFH45181.1 - 2.7e-37 128.1 0.0 3.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KFH45181.1 - 2.6e-16 60.6 20.6 2.6e-16 60.6 20.6 3.2 3 1 0 3 3 3 1 PI31 proteasome regulator HR1 PF02185.16 KFH45182.1 - 3.4e-22 78.3 17.8 8.1e-12 45.1 2.6 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 KFH45182.1 - 2.4e-19 68.9 28.3 7.9e-12 44.9 10.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFH45182.1 - 6.2e-15 55.3 0.1 1.3e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45182.1 - 1.8e-08 34.0 0.1 3.1e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFH45182.1 - 0.00016 21.9 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-RING_9 PF13901.6 KFH45182.1 - 2.5 8.0 19.7 2.5 8.0 5.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon ALG3 PF05208.13 KFH45183.1 - 3.4e-142 474.1 16.8 4e-142 473.9 16.8 1.0 1 0 0 1 1 1 1 ALG3 protein PAT1 PF09770.9 KFH45184.1 - 0 1270.0 7.4 0 1269.0 7.4 1.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.15 KFH45185.1 - 1.3e-150 502.1 36.7 1.5e-150 501.9 36.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PALP PF00291.25 KFH45186.1 - 3.2e-33 115.4 0.0 5.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KFH45186.1 - 2.3e-08 34.5 0.0 5.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain SH3_3 PF08239.11 KFH45187.1 - 0.0067 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Thioredoxin PF00085.20 KFH45188.1 - 1.7e-26 92.2 0.0 2.1e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFH45188.1 - 6.7e-08 32.9 0.1 1.4e-07 31.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFH45188.1 - 3.7e-05 24.0 0.0 0.00012 22.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFH45188.1 - 8.4e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KFH45188.1 - 0.00017 21.4 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFH45188.1 - 0.00085 19.5 0.1 0.0015 18.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KFH45188.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 KFH45188.1 - 0.015 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 KFH45188.1 - 0.052 13.5 0.0 0.071 13.1 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 KFH45188.1 - 0.082 12.6 0.2 1.2 8.8 0.1 2.0 1 1 1 2 2 2 0 Redoxin Thioredoxin_5 PF13743.6 KFH45188.1 - 0.2 11.3 0.0 0.67 9.6 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin Nuf2 PF03800.14 KFH45189.1 - 2.2e-41 141.2 2.0 4.6e-41 140.2 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KFH45189.1 - 1.4e-36 125.0 19.1 1.4e-36 125.0 19.1 4.4 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain P22_AR_C PF10548.9 KFH45189.1 - 0.012 15.7 0.2 0.45 10.7 0.2 2.6 2 0 0 2 2 2 0 P22AR C-terminal domain Bacillus_HBL PF05791.11 KFH45189.1 - 0.032 14.1 18.1 0.13 12.0 2.5 3.3 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 KFH45189.1 - 8.3 6.5 50.1 3.3 7.8 22.4 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 KFH45190.1 - 8e-25 87.5 52.0 5.7e-14 51.8 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_15 PF01793.16 KFH45191.1 - 1e-127 425.9 9.2 1.3e-127 425.6 9.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF89 PF01937.19 KFH45192.1 - 4.1e-128 427.3 0.0 4.7e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Adaptin_N PF01602.20 KFH45193.1 - 3.3e-103 346.0 0.0 4.1e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFH45193.1 - 9.8e-16 58.2 0.7 3.1e-14 53.3 0.0 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFH45193.1 - 1.1e-09 38.6 9.0 0.00021 21.6 0.0 5.2 4 2 2 6 6 5 3 HEAT repeats HEAT PF02985.22 KFH45193.1 - 2.2e-07 30.6 2.7 0.033 14.4 0.0 5.9 6 0 0 6 6 5 1 HEAT repeat Cohesin_HEAT PF12765.7 KFH45193.1 - 5.7e-06 26.5 0.9 0.023 15.0 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KFH45193.1 - 0.00032 21.1 2.6 3.7 8.1 0.0 4.8 4 0 0 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 KFH45193.1 - 0.13 11.9 0.1 4.8 6.7 0.0 2.9 2 1 0 2 2 2 0 CLASP N terminal DUF5578 PF17741.1 KFH45193.1 - 0.13 11.7 1.3 35 3.7 0.2 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5578) Cnd3 PF12719.7 KFH45193.1 - 0.21 10.7 1.0 1.7 7.8 0.1 2.9 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain VIR_N PF15912.5 KFH45193.1 - 0.44 10.1 10.2 0.74 9.4 10.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Nop14 PF04147.12 KFH45193.1 - 1.6 6.8 30.4 2.6 6.1 30.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFH45193.1 - 3.8 6.7 22.2 7.1 5.8 22.2 1.4 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 KFH45193.1 - 3.9 7.6 4.6 7.3 6.7 4.6 1.4 1 0 0 1 1 1 0 DDHD domain DUF5523 PF17661.1 KFH45193.1 - 4.4 6.9 19.5 8.4 6.0 19.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RNA_pol_3_Rpc31 PF11705.8 KFH45193.1 - 4.6 7.4 27.5 12 6.1 27.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RR_TM4-6 PF06459.12 KFH45193.1 - 6.8 6.4 15.7 13 5.5 15.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 KFH45193.1 - 6.9 7.1 8.1 16 5.9 8.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KFH45193.1 - 7.1 5.3 10.0 12 4.5 10.0 1.3 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 KFH45193.1 - 7.2 6.6 15.8 19 5.3 15.8 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-MYND PF01753.18 KFH45194.1 - 2.2e-10 40.4 13.6 3.9e-10 39.6 13.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KFH45194.1 - 0.14 12.5 11.5 0.31 11.4 11.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-CCHC PF00098.23 KFH45195.1 - 9.7e-07 28.6 1.2 1.6e-06 27.9 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFH45195.1 - 0.06 13.3 0.2 0.06 13.3 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFH45195.1 - 0.22 11.3 0.2 0.4 10.5 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-AN1 PF01428.16 KFH45196.1 - 2.4e-25 88.4 26.2 1.1e-12 47.8 11.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFH45196.1 - 0.029 14.7 15.3 0.24 11.8 7.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.21 KFH45196.1 - 0.033 14.4 4.3 0.033 14.4 4.3 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 KFH45196.1 - 1.9 8.8 16.9 10 6.5 0.9 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain Rad4 PF03835.15 KFH45197.1 - 1.1e-31 109.5 0.1 1.1e-31 109.5 0.1 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFH45197.1 - 1.1e-26 93.0 0.4 2.5e-26 91.8 0.4 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KFH45197.1 - 1e-18 66.9 0.7 2.4e-18 65.7 0.7 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFH45197.1 - 1.8e-14 54.4 0.2 1.8e-14 54.4 0.2 4.7 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KFH45197.1 - 0.0035 17.8 0.0 0.017 15.5 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily Ribosom_S12_S23 PF00164.25 KFH45198.1 - 9.4e-30 102.6 0.5 1.3e-29 102.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KFH45198.1 - 0.16 12.7 0.0 0.44 11.3 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S12 SLAIN PF15301.6 KFH45198.1 - 2.1 7.5 6.2 2.7 7.2 6.2 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family XAP5 PF04921.14 KFH45199.1 - 1.5e-91 306.7 0.3 2.9e-91 305.7 0.0 1.5 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KFH45199.1 - 0.0011 19.5 9.4 0.0011 19.5 9.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4604) DUF4545 PF15078.6 KFH45199.1 - 0.4 9.6 4.8 0.55 9.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) PBP1_TM PF14812.6 KFH45199.1 - 0.48 10.8 7.7 1.3 9.4 7.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 KFH45199.1 - 0.62 8.8 2.3 0.83 8.4 2.3 1.1 1 0 0 1 1 1 0 Presenilin NAM-associated PF14303.6 KFH45199.1 - 3.1 8.5 12.8 5.7 7.6 12.8 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nucleo_P87 PF07267.11 KFH45199.1 - 6.1 5.6 7.3 9.1 5.0 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA_22 PF13401.6 KFH45200.1 - 0.001 19.3 0.2 0.073 13.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KFH45200.1 - 0.0043 16.4 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KFH45200.1 - 0.019 15.3 0.1 0.2 12.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFH45200.1 - 0.045 13.0 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KFH45200.1 - 0.074 13.1 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain KCNQC3-Ank-G_bd PF11956.8 KFH45200.1 - 7 7.0 10.5 0.22 11.8 0.4 3.1 4 0 0 4 4 4 0 Ankyrin-G binding motif of KCNQ2-3 KilA-N PF04383.13 KFH45201.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.7 2 2 0 2 2 2 0 KilA-N domain Mitofilin PF09731.9 KFH45201.1 - 0.17 10.7 21.8 0.25 10.1 21.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1993 PF09351.10 KFH45201.1 - 3.8 7.6 6.9 2.1 8.5 1.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) AnmK PF03702.14 KFH45202.1 - 7e-86 288.6 0.0 8.2e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Glyco_hydro_12 PF01670.16 KFH45203.1 - 6.3e-32 111.3 1.1 4.1e-30 105.4 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 DUF4524 PF15025.6 KFH45203.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) HORMA PF02301.18 KFH45204.1 - 9.3e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Sugar_tr PF00083.24 KFH45205.1 - 1.8e-62 211.7 11.1 2e-62 211.5 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45205.1 - 1e-17 64.2 21.5 1.4e-17 63.7 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFH45206.1 - 2.8e-31 108.7 33.0 2.8e-31 108.7 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45206.1 - 5e-12 45.4 5.1 5e-12 45.4 5.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFH45206.1 - 2.3e-08 33.0 1.7 3.8e-08 32.2 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KFH45206.1 - 0.05 11.8 0.1 0.05 11.8 0.1 2.6 3 1 0 3 3 3 0 BT1 family MFS_1 PF07690.16 KFH45207.1 - 9.9e-26 90.5 21.1 3.1e-20 72.4 18.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MTP18 PF10558.9 KFH45208.1 - 1.9e-81 272.1 0.1 2.5e-81 271.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) AltA1 PF16541.5 KFH45209.1 - 3.7e-27 95.3 0.1 5.1e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 AA_permease_2 PF13520.6 KFH45210.1 - 1.5e-81 274.4 32.9 1.8e-81 274.1 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH45210.1 - 2.2e-13 49.7 27.8 3.2e-13 49.1 27.8 1.2 1 0 0 1 1 1 1 Amino acid permease PsbN PF02468.15 KFH45210.1 - 0.35 10.7 1.5 2 8.3 1.5 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) HhH-GPD PF00730.25 KFH45211.1 - 5.2e-14 52.6 0.0 9.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GCS PF03074.16 KFH45212.1 - 4.4e-177 588.9 0.0 5.2e-177 588.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Clat_adaptor_s PF01217.20 KFH45214.1 - 5.6e-47 159.3 1.4 8.1e-47 158.7 0.5 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KFH45214.1 - 0.022 15.5 0.1 0.044 14.5 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain DUF5308 PF17233.2 KFH45216.1 - 9e-56 188.6 9.3 1.2e-55 188.3 9.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) BicD PF09730.9 KFH45216.1 - 0.0038 15.7 0.4 0.0044 15.5 0.4 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Rrn6 PF10214.9 KFH45216.1 - 0.009 14.6 5.5 0.0098 14.4 5.5 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor ORC6 PF05460.13 KFH45216.1 - 0.046 13.0 3.5 0.053 12.8 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.6 KFH45216.1 - 5.9 6.6 8.2 24 4.6 8.2 1.9 1 1 0 1 1 1 0 FAM176 family SspB PF04386.13 KFH45216.1 - 7.5 6.4 7.2 8.9 6.2 0.0 2.2 1 1 1 2 2 2 0 Stringent starvation protein B HATPase_c PF02518.26 KFH45217.1 - 2.1e-26 92.6 0.1 1.3e-24 86.9 0.1 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH45217.1 - 3.1e-26 91.7 0.1 5.8e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFH45217.1 - 5e-14 52.1 0.0 1.2e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KFH45217.1 - 0.001 19.4 0.0 0.026 14.9 0.0 2.5 2 0 0 2 2 2 1 HAMP domain N_BRCA1_IG PF16158.5 KFH45218.1 - 1.1e-33 116.0 0.1 3.1e-33 114.5 0.1 1.9 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KFH45218.1 - 7.8e-20 70.4 51.5 1.1e-05 25.1 7.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KFH45218.1 - 1.3 9.4 48.8 0.55 10.6 3.7 4.6 4 0 0 4 4 4 0 C1 domain Anp1 PF03452.14 KFH45220.1 - 4.2e-100 334.5 0.1 9.7e-100 333.3 0.1 1.5 1 1 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFH45220.1 - 0.0064 16.3 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 FHA PF00498.26 KFH45221.1 - 1.9e-10 40.9 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 KFH45221.1 - 0.16 12.2 0.0 0.57 10.5 0.0 1.9 1 1 0 1 1 1 0 FHA domain Gln-synt_C PF00120.24 KFH45222.1 - 4.2e-15 55.6 0.0 4.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFH45222.1 - 1.6e-12 47.0 0.0 2.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.24 KFH45222.1 - 0.002 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0160 PF03690.13 KFH45223.1 - 8.1e-132 439.7 0.0 9.1e-132 439.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Tubulin PF00091.25 KFH45225.1 - 2.3e-63 214.0 0.0 5.4e-41 141.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFH45225.1 - 3.7e-45 153.1 0.3 8.8e-45 151.9 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFH45225.1 - 1.3e-07 31.9 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFH45225.1 - 0.045 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Tubulin domain DUF2373 PF10180.9 KFH45226.1 - 2e-23 82.0 0.1 4.5e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 KFH45227.1 - 2.5e-49 167.4 0.1 3.4e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFH45227.1 - 5.4e-11 42.0 0.2 5.4e-11 42.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn-ribbon_8 PF09723.10 KFH45228.1 - 1.4 9.1 5.4 34 4.7 5.4 2.3 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_S27e PF01667.17 KFH45228.1 - 4.5 7.1 10.2 0.34 10.7 3.7 2.0 1 1 1 2 2 2 0 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 KFH45228.1 - 7.8 6.6 9.4 1.7 8.7 2.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon TMEM234 PF10639.9 KFH45229.1 - 1.8e-33 115.0 0.2 2.2e-33 114.7 0.2 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KFH45229.1 - 6.6e-05 23.1 4.8 0.11 12.7 3.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family F-box PF00646.33 KFH45230.1 - 2.6e-05 23.9 0.8 7.8e-05 22.5 0.8 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFH45230.1 - 0.0046 16.8 1.3 0.013 15.3 0.3 2.2 2 0 0 2 2 2 1 F-box-like PhyH PF05721.13 KFH45231.1 - 5.8e-63 213.0 0.0 6.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_5 PF00266.19 KFH45232.1 - 4.2e-92 309.0 0.0 5e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFH45232.1 - 2e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFH45232.1 - 3.3e-05 23.4 0.1 8.9e-05 22.0 0.1 1.7 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFH45232.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KFH45232.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF92 PF01940.16 KFH45233.1 - 1.6e-88 296.1 0.3 1.9e-88 295.9 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 MFS_1 PF07690.16 KFH45234.1 - 6.2e-23 81.3 43.4 2.3e-22 79.4 41.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily SUIM_assoc PF16619.5 KFH45234.1 - 4.9 7.3 9.6 10 6.3 9.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ADIP PF11559.8 KFH45235.1 - 1e-41 142.5 4.1 1e-41 142.5 4.1 3.0 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KFH45235.1 - 0.0048 16.4 1.4 0.0048 16.4 1.4 2.9 3 1 1 4 4 4 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KFH45235.1 - 0.015 15.5 8.3 0.13 12.4 2.9 3.0 2 0 0 2 2 2 0 Tropomyosin like PMC2NT PF08066.12 KFH45235.1 - 0.054 14.2 6.0 0.24 12.1 1.2 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain TTKRSYEDQ PF10212.9 KFH45235.1 - 0.098 11.6 2.4 0.24 10.3 1.3 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Csm1_N PF18504.1 KFH45235.1 - 0.25 11.7 6.3 4.6 7.7 1.4 3.8 4 0 0 4 4 4 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KFH45235.1 - 0.76 9.8 10.7 0.28 11.2 2.6 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 KFH45235.1 - 1.3 6.9 4.7 2.1 6.2 3.9 1.6 1 1 1 2 2 2 0 Prominin Spc7 PF08317.11 KFH45235.1 - 2.2 7.1 12.8 0.086 11.7 3.8 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 KFH45235.1 - 7.4 5.7 4.8 5 6.3 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein GATA PF00320.27 KFH45236.1 - 3.1e-15 55.5 3.5 5.5e-15 54.7 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger DEAD PF00270.29 KFH45238.1 - 4e-35 121.2 0.0 3e-34 118.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH45238.1 - 3.5e-24 85.3 0.0 7.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFH45238.1 - 0.0004 19.8 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFH45238.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFH45238.1 - 0.16 12.3 0.2 1 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KFH45239.1 - 2.5e-08 33.9 4.8 3.7e-08 33.3 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2076 PF09849.9 KFH45239.1 - 0.25 11.3 5.5 0.5 10.4 5.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Syja_N PF02383.18 KFH45240.1 - 8.3e-97 324.3 0.0 1.1e-96 323.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFH45240.1 - 2.5e-39 133.6 0.0 4.7e-39 132.7 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase LRR_4 PF12799.7 KFH45241.1 - 0.0013 19.1 14.3 2.5 8.6 2.4 5.1 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.24 KFH45241.1 - 0.017 15.2 8.7 0.58 10.3 0.1 4.1 2 2 1 3 3 3 0 Receptor L domain LRR_8 PF13855.6 KFH45241.1 - 0.022 14.5 3.4 3.5 7.5 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat WD40 PF00400.32 KFH45242.1 - 1.4e-35 120.7 12.5 4.5e-10 40.0 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45242.1 - 2.8e-12 46.7 0.4 0.016 15.5 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH45242.1 - 2e-07 30.3 0.1 0.18 10.7 0.0 3.7 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFH45242.1 - 0.00095 17.9 2.4 0.14 10.8 0.1 3.5 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFH45242.1 - 0.021 13.7 2.4 0.03 13.2 0.0 2.3 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFH45242.1 - 0.03 12.6 0.0 0.051 11.9 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KFH45242.1 - 0.031 13.0 0.1 1.2 7.8 0.0 2.8 2 1 2 4 4 4 0 Nup133 N terminal like HPS3_N PF14761.6 KFH45242.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 USP7_C2 PF14533.6 KFH45242.1 - 0.19 11.4 0.0 0.49 10.1 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal p450 PF00067.22 KFH45244.1 - 3.8e-10 39.1 0.0 3.9e-07 29.2 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 DUF4538 PF15061.6 KFH45244.1 - 0.06 13.1 0.7 0.13 12.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Transketolase_N PF00456.21 KFH45245.1 - 9.3e-157 521.2 0.0 1.2e-156 520.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFH45245.1 - 1.1e-44 152.2 0.0 2e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFH45245.1 - 5e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KFH45245.1 - 5.7e-05 22.4 0.0 0.00064 19.0 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.21 KFH45245.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain zf-RING_13 PF17977.1 KFH45245.1 - 0.15 12.2 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1264 PF06884.11 KFH45246.1 - 1.8e-62 210.0 0.3 1.9e-62 209.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Maf1 PF09174.10 KFH45247.1 - 1.4e-56 191.4 0.0 2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Btz PF09405.10 KFH45248.1 - 1.5e-25 90.0 3.2 1.5e-25 90.0 3.2 1.9 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Gln-synt_C PF00120.24 KFH45249.1 - 2.1e-64 217.7 0.0 5.7e-64 216.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KFH45249.1 - 1.9e-15 57.5 0.0 4.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 KFH45249.1 - 0.00056 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Ran_BP1 PF00638.18 KFH45250.1 - 1.7e-11 44.4 0.2 3.6e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KFH45250.1 - 0.00087 20.1 18.6 0.00087 20.1 18.6 9.9 1 1 8 9 9 9 4 Nucleoporin FG repeat region WH1 PF00568.23 KFH45250.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Endosulfine PF04667.17 KFH45252.1 - 3.8e-27 94.2 0.0 6.5e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region BESS PF02944.20 KFH45252.1 - 0.23 11.3 0.3 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 BESS motif CN_hydrolase PF00795.22 KFH45253.1 - 4.5e-58 196.6 0.0 5.1e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CsbD PF05532.12 KFH45255.1 - 3.1e-17 62.2 22.8 1.2e-06 28.4 0.2 4.9 4 1 0 4 4 4 4 CsbD-like Toxin_11 PF07473.11 KFH45256.1 - 0.0049 16.9 0.7 0.0091 16.0 0.7 1.5 1 0 0 1 1 1 1 Spasmodic peptide gm9a; conotoxin from Conus species Spermine_synth PF01564.17 KFH45257.1 - 1.7e-67 226.5 0.0 8e-56 188.4 0.0 2.3 2 0 0 2 2 2 2 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFH45257.1 - 3.5e-22 78.0 0.1 5.7e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFH45257.1 - 0.00064 20.4 0.0 0.0012 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KFH45257.1 - 0.0051 16.1 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KFH45257.1 - 0.0064 17.2 0.3 0.05 14.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFH45257.1 - 0.043 13.8 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RRP7 PF12923.7 KFH45258.1 - 2.8e-28 98.4 15.6 2.8e-28 98.4 15.6 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KFH45258.1 - 3.9e-17 62.5 0.0 9.1e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain ANF_receptor PF01094.28 KFH45258.1 - 0.044 12.9 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region CDRT4 PF15213.6 KFH45258.1 - 0.47 11.1 6.4 0.41 11.3 0.2 2.3 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein MARVEL PF01284.23 KFH45259.1 - 0.048 13.7 14.4 0.78 9.8 14.7 2.4 1 1 0 1 1 1 0 Membrane-associating domain DUF4305 PF14146.6 KFH45259.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) Fzo_mitofusin PF04799.13 KFH45259.1 - 1 8.9 2.4 2 8.0 2.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region FtsX PF02687.21 KFH45259.1 - 2.2 8.8 16.4 6.1 7.4 12.6 2.7 2 1 0 2 2 2 0 FtsX-like permease family Polysacc_synt_C PF14667.6 KFH45259.1 - 3.2 7.8 15.8 0.62 10.1 9.9 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain BAR PF03114.18 KFH45260.1 - 1.6e-69 234.2 7.9 2.1e-69 233.8 7.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFH45260.1 - 1.2e-14 53.6 0.1 2.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH45260.1 - 3e-12 46.2 0.0 5.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH45260.1 - 1.1e-07 31.4 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TMPIT PF07851.13 KFH45260.1 - 0.083 12.1 5.1 0.88 8.8 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Vps5 PF09325.10 KFH45260.1 - 0.14 11.7 6.5 0.74 9.3 3.4 2.1 2 0 0 2 2 2 0 Vps5 C terminal like GMC_oxred_N PF00732.19 KFH45261.1 - 2.4e-43 148.6 0.0 1.2e-29 103.7 0.0 3.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH45261.1 - 1.8e-35 122.6 0.1 3.1e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KFH45261.1 - 5.5e-06 26.2 1.1 0.00027 20.6 0.3 3.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH45261.1 - 6.6e-06 25.5 0.0 0.0056 15.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFH45261.1 - 0.00026 20.2 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFH45261.1 - 0.00036 19.8 0.2 0.001 18.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH45261.1 - 0.00079 19.6 0.2 0.0024 18.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH45261.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KFH45261.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FTHFS PF01268.19 KFH45262.1 - 7.3e-255 846.4 1.2 8.4e-255 846.2 0.1 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFH45262.1 - 7.7e-67 223.6 0.7 7.7e-67 223.6 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFH45262.1 - 1.9e-29 102.3 0.2 4e-29 101.2 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 KFH45262.1 - 0.057 12.9 0.4 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.18 KFH45263.1 - 2.2e-06 27.7 10.9 2.2e-06 27.7 10.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.20 KFH45264.1 - 5.8e-113 377.6 0.4 7.3e-113 377.3 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFH45264.1 - 4.2e-14 52.4 0.6 4e-08 32.9 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFH45264.1 - 0.00033 20.1 1.5 0.053 12.9 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFH45264.1 - 0.0089 16.2 0.2 1.8 8.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KFH45264.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KFH45264.1 - 0.046 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFH45264.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IFRD PF05004.13 KFH45265.1 - 1.8e-31 109.4 0.0 2.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 KFH45265.1 - 3.1e-05 23.3 0.0 4.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain DUF765 PF05570.11 KFH45265.1 - 0.039 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Adaptin_N PF01602.20 KFH45265.1 - 0.049 12.2 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region ATP-synt_C PF00137.21 KFH45266.1 - 6.7e-33 112.8 31.9 7e-22 77.5 14.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Penicillinase_R PF03965.16 KFH45267.1 - 0.044 14.1 0.2 0.14 12.5 0.2 1.9 1 0 0 1 1 1 0 Penicillinase repressor G-patch PF01585.23 KFH45268.1 - 1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFH45268.1 - 8.7e-05 22.3 0.1 0.0002 21.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH45268.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_34 PF11312.8 KFH45270.1 - 2.9e-104 348.6 0.0 3.3e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase SNF2_N PF00176.23 KFH45271.1 - 4.1e-66 223.1 0.1 8.8e-66 222.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH45271.1 - 1.5e-22 80.0 0.1 5.5e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH45271.1 - 5.6e-09 36.2 0.0 2.2e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFH45271.1 - 5.3e-05 22.6 0.0 5.3e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFH45271.1 - 8e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TFIIA PF03153.13 KFH45271.1 - 0.21 11.6 11.4 0.045 13.7 1.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.19 KFH45271.1 - 0.67 10.0 8.0 3.9 7.7 8.0 2.5 1 0 0 1 1 1 0 AT hook motif tRNA_bind PF01588.20 KFH45272.1 - 1e-21 76.8 0.1 2.3e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KFH45272.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH45272.1 - 0.002 18.3 1.8 0.0037 17.4 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pol_alpha_B_N PF08418.10 KFH45272.1 - 0.32 10.9 4.6 2.7 7.9 1.9 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Chitin_synth_1 PF01644.17 KFH45273.1 - 1.1e-69 233.6 0.0 1.6e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KFH45273.1 - 1.8e-28 99.5 0.1 1.6e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KFH45273.1 - 1.4e-24 85.8 0.1 3e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KFH45273.1 - 6.4e-10 39.3 7.2 5.7e-09 36.2 7.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 RsfS PF02410.15 KFH45274.1 - 4.6e-12 46.2 0.0 1.1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Iso_dh PF00180.20 KFH45275.1 - 7.1e-85 285.2 0.0 8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L1 PF00687.21 KFH45276.1 - 2.5e-67 226.6 0.2 3.9e-67 225.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family bZIP_1 PF00170.21 KFH45278.1 - 0.00037 20.5 4.6 0.0012 18.9 4.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor 23S_rRNA_IVP PF05635.11 KFH45278.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein bZIP_2 PF07716.15 KFH45278.1 - 1.2 9.3 10.1 0.094 12.8 5.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper CRAL_TRIO PF00650.20 KFH45279.1 - 3.6e-25 88.5 0.0 5.4e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH45279.1 - 7.2e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHP PF02811.19 KFH45280.1 - 1.2e-14 55.0 0.0 2.2e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 PHP domain DUF1952 PF09189.10 KFH45280.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) adh_short PF00106.25 KFH45281.1 - 2.9e-22 79.1 0.0 5.6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45281.1 - 2.7e-17 63.1 0.3 4e-17 62.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH45281.1 - 4.8e-09 36.0 0.0 6.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFH45281.1 - 2.4e-08 34.1 0.2 3.6e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFH45281.1 - 3.6e-08 33.5 0.2 5.7e-08 32.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 KFH45281.1 - 0.0031 17.5 0.0 0.0042 17.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF1771 PF08590.10 KFH45281.1 - 0.046 14.1 1.5 0.046 14.1 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) 3HCDH_N PF02737.18 KFH45281.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFH45281.1 - 0.099 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KFH45281.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KFH45281.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_trans_4_4 PF13579.6 KFH45281.1 - 0.24 11.8 1.8 0.82 10.1 0.2 2.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain GalP_UDP_transf PF01087.22 KFH45282.1 - 5.6e-71 238.8 0.1 7.9e-69 231.8 0.0 2.1 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFH45282.1 - 6.3e-59 198.5 0.0 3.4e-58 196.0 0.0 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KFH45282.1 - 0.024 15.3 0.0 0.084 13.6 0.0 2.0 2 0 0 2 2 2 0 HIT domain PWI PF01480.17 KFH45283.1 - 1.2e-14 54.4 0.2 2.4e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KFH45283.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rap1_C PF11626.8 KFH45283.1 - 1.6 8.8 12.4 2.2 8.4 0.0 3.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short PF00106.25 KFH45284.1 - 7.1e-37 126.8 0.0 9.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45284.1 - 1.8e-23 83.3 0.0 2.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH45284.1 - 1.3e-05 25.2 0.0 2.3e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFH45284.1 - 0.0058 15.8 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFH45284.1 - 0.0074 15.7 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KFH45284.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH45284.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFH45284.1 - 0.011 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFH45284.1 - 0.033 14.4 0.0 0.09 12.9 0.0 1.8 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 KFH45284.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding DCB PF16213.5 KFH45284.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Zn_clus PF00172.18 KFH45287.1 - 0.0071 16.4 5.8 0.013 15.6 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFH45288.1 - 9.3e-34 117.0 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45288.1 - 4.6e-11 42.5 0.0 6.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFH45288.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH45288.1 - 0.05 13.5 0.0 6.7 6.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH45288.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Tam41_Mmp37 PF09139.11 KFH45289.1 - 2e-124 415.2 0.0 2.4e-124 415.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SH3BGR PF04908.15 KFH45290.1 - 0.00053 20.1 0.3 0.003 17.7 0.0 2.4 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein CDC27 PF09507.10 KFH45290.1 - 2.8 7.2 29.3 3.6 6.9 29.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.11 KFH45290.1 - 6.5 5.1 17.7 7.9 4.9 17.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DPPIV_N PF00930.21 KFH45291.1 - 1.2e-106 356.5 0.1 1.6e-106 356.1 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFH45291.1 - 3.3e-53 180.3 1.2 6.3e-53 179.4 0.6 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFH45291.1 - 0.00019 21.2 0.1 0.00033 20.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH45291.1 - 0.0024 18.5 12.3 0.0045 17.6 3.2 3.5 2 2 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KFH45291.1 - 0.01 15.5 0.5 0.058 13.0 0.2 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 KFH45291.1 - 0.057 13.4 0.2 12 5.9 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat UPF0121 PF03661.13 KFH45292.1 - 1.1e-31 110.1 2.0 1.4e-31 109.7 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Phosphodiest PF01663.22 KFH45294.1 - 1.1e-13 51.5 0.3 2.5e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFH45294.1 - 0.00051 19.5 0.6 0.0012 18.3 0.6 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFH45294.1 - 0.00079 18.9 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Epimerase PF01370.21 KFH45295.1 - 3.1e-48 164.4 0.0 3.9e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH45295.1 - 9.1e-48 163.4 0.0 1.4e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFH45295.1 - 4e-17 62.1 0.0 2.4e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFH45295.1 - 5.6e-14 52.0 0.0 7.1e-12 45.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFH45295.1 - 9.3e-13 47.9 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFH45295.1 - 3.7e-09 36.3 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45295.1 - 6.1e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFH45295.1 - 9.8e-07 28.2 0.0 1.4e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFH45295.1 - 7.9e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KFH45295.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 KFH45295.1 - 0.0055 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KFH45295.1 - 0.011 15.2 0.1 0.077 12.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Rhodanese PF00581.20 KFH45296.1 - 2.3e-14 53.8 0.0 2.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF1957 PF09210.11 KFH45296.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Ank_2 PF12796.7 KFH45298.1 - 1.9e-42 143.7 15.4 1.5e-07 31.9 0.0 14.2 13 2 3 16 16 16 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH45298.1 - 3.5e-20 70.0 8.4 0.0052 17.2 0.0 17.2 18 0 0 18 18 18 2 Ankyrin repeat Ank_4 PF13637.6 KFH45298.1 - 1.6e-18 66.8 15.9 0.75 10.5 0.0 14.7 13 2 2 15 15 15 5 Ankyrin repeats (many copies) Ank PF00023.30 KFH45298.1 - 1.1e-17 63.5 17.0 8.3e-05 22.9 0.0 14.4 13 1 0 13 13 13 2 Ankyrin repeat Ank_5 PF13857.6 KFH45298.1 - 7.3e-16 58.0 15.6 7.1e-07 29.4 0.0 12.1 13 2 2 15 15 15 3 Ankyrin repeats (many copies) RNA_pol PF00940.19 KFH45300.1 - 8.3e-183 607.9 0.0 1.2e-182 607.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFH45300.1 - 3.5e-90 302.8 0.3 5.3e-90 302.2 0.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.14 KFH45302.1 - 1.1e-38 132.6 0.0 1.8e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KFH45302.1 - 1.8e-09 37.8 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF1769 PF08588.10 KFH45303.1 - 0.1 12.8 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) DEAD PF00270.29 KFH45304.1 - 6.3e-47 159.6 0.0 1.1e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH45304.1 - 3.5e-25 88.5 0.0 2e-24 86.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFH45304.1 - 3.2e-21 75.3 0.1 1.7e-20 73.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFH45304.1 - 4.8e-07 29.9 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFH45304.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Roughex PF06020.11 KFH45304.1 - 1.2 8.2 11.2 2.6 7.0 11.2 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Trehalase PF01204.18 KFH45305.1 - 8.1e-123 410.9 0.3 7.9e-122 407.7 0.3 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KFH45305.1 - 1.2e-05 24.4 0.1 0.00037 19.6 0.0 2.1 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Cytochrom_B561 PF03188.16 KFH45306.1 - 0.0002 21.5 9.8 0.0002 21.5 9.8 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Phage_holin_2_4 PF16082.5 KFH45306.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.3 4 0 0 4 4 4 0 Bacteriophage holin family, superfamily II-like CYSTM PF12734.7 KFH45306.1 - 0.84 10.0 1.9 55 4.2 0.1 3.4 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance DUF4079 PF13301.6 KFH45306.1 - 7.4 6.7 15.9 10 6.3 3.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) YbjQ_1 PF01906.17 KFH45307.1 - 1.2e-24 86.9 0.1 1.5e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding MaoC_dehydratas PF01575.19 KFH45308.1 - 0.012 15.1 0.7 0.034 13.7 0.7 1.6 1 1 0 1 1 1 0 MaoC like domain TauD PF02668.16 KFH45309.1 - 3.3e-05 23.8 0.0 3.8e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family QRPTase_C PF01729.19 KFH45310.1 - 3.4e-54 183.1 0.1 4.2e-54 182.9 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KFH45310.1 - 1.1e-16 60.7 0.1 5.4e-16 58.4 0.0 2.2 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Palm_thioest PF02089.15 KFH45311.1 - 6.7e-80 268.4 0.0 7.8e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KFH45311.1 - 0.0046 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) SurE PF01975.17 KFH45312.1 - 1e-40 139.6 0.0 4.7e-40 137.4 0.0 1.8 2 0 0 2 2 2 1 Survival protein SurE Erg28 PF03694.13 KFH45313.1 - 1.5e-43 147.6 0.2 1.8e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein ABC_tran PF00005.27 KFH45314.1 - 2.4e-47 160.9 0.2 2.8e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFH45314.1 - 1.1e-25 90.4 26.2 1.3e-17 64.0 17.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFH45314.1 - 9.1e-22 78.2 2.6 3.8e-05 23.7 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH45314.1 - 5e-09 35.8 0.8 0.00027 20.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFH45314.1 - 1.5e-07 31.1 1.6 0.2 11.1 0.1 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH45314.1 - 4e-07 30.7 0.8 0.029 14.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH45314.1 - 0.00019 21.4 0.6 0.79 9.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 KFH45314.1 - 0.00086 19.0 0.3 0.82 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFH45314.1 - 0.0011 18.8 0.1 1 9.0 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KFH45314.1 - 0.0014 18.4 0.1 1.3 8.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 KFH45314.1 - 0.0042 17.8 0.0 2.4 8.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KFH45314.1 - 0.0054 17.1 0.1 2.8 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFH45314.1 - 0.026 14.8 0.3 6 7.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFH45314.1 - 0.097 11.9 0.1 7.6 5.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin Rad17 PF03215.15 KFH45314.1 - 0.1 12.5 0.0 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 KFH45314.1 - 0.1 12.2 0.3 15 5.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 KFH45314.1 - 0.15 11.9 0.2 19 5.0 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal 4HBT_3 PF13622.6 KFH45315.1 - 2e-47 162.5 0.4 2.5e-47 162.2 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFH45315.1 - 0.056 13.3 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioesterase Nucleoporin_N PF08801.11 KFH45316.1 - 8.6e-91 304.8 1.4 1.2e-90 304.4 1.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFH45316.1 - 5e-51 174.2 0.4 2.5e-49 168.5 0.1 2.2 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Hist_deacetyl PF00850.19 KFH45317.1 - 2.6e-50 171.6 0.1 4.6e-50 170.8 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KFH45317.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RTP801 C-terminal region DUF999 PF06198.11 KFH45317.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) DUF2781 PF10914.8 KFH45318.1 - 5.7e-28 98.2 5.8 6.5e-28 98.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Clathrin PF00637.20 KFH45319.1 - 8.7e-203 664.4 39.5 5.6e-32 110.6 0.3 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFH45319.1 - 2.8e-34 115.8 0.1 4.2e-07 30.0 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFH45319.1 - 4e-31 106.7 0.3 4e-31 106.7 0.3 2.8 3 0 0 3 3 3 1 Clathrin-H-link TPR_14 PF13428.6 KFH45319.1 - 6.9e-06 26.5 6.2 12 7.0 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat PPR PF01535.20 KFH45319.1 - 0.018 15.3 0.6 79 3.8 0.0 5.5 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.6 KFH45319.1 - 0.022 15.0 5.0 1.9 8.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat 6PF2K PF01591.18 KFH45319.1 - 0.028 13.7 0.1 0.093 12.0 0.1 1.8 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Coatomer_WDAD PF04053.14 KFH45319.1 - 0.034 13.2 10.3 1.1 8.2 0.2 4.6 6 0 0 6 6 6 0 Coatomer WD associated region TPR_7 PF13176.6 KFH45319.1 - 0.11 12.6 9.8 5.2 7.3 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFH45319.1 - 0.13 12.8 6.3 14 6.3 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KFH45319.1 - 0.86 9.9 7.0 2.5 8.4 0.1 5.3 6 1 1 7 7 7 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 KFH45319.1 - 1.1 9.2 7.1 11 6.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFH45319.1 - 1.5 9.1 9.8 16 5.9 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat CD99L2 PF12301.8 KFH45320.1 - 0.012 15.9 0.7 0.014 15.7 0.7 1.0 1 0 0 1 1 1 0 CD99 antigen like protein 2 AflR PF08493.10 KFH45320.1 - 5.6 6.4 9.0 6.2 6.2 9.0 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein zf-RING_2 PF13639.6 KFH45322.1 - 2.5e-08 34.1 8.1 2.5e-08 34.1 8.1 1.9 2 0 0 2 2 1 1 Ring finger domain FANCL_C PF11793.8 KFH45322.1 - 1.9e-05 24.7 8.0 5.4e-05 23.3 8.0 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KFH45322.1 - 0.00016 21.9 6.9 0.00043 20.5 6.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFH45322.1 - 0.00019 21.4 3.0 0.00058 19.9 3.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KFH45322.1 - 0.0024 18.0 7.6 0.0052 16.9 7.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 KFH45322.1 - 0.0028 17.5 9.8 0.0028 17.5 9.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KFH45322.1 - 0.0041 17.0 2.8 0.0041 17.0 2.8 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KFH45322.1 - 0.0049 16.4 4.7 0.011 15.4 4.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFH45322.1 - 0.034 14.4 8.1 0.07 13.4 8.1 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 KFH45322.1 - 0.041 13.7 8.5 0.089 12.6 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH45322.1 - 0.3 11.0 9.8 0.043 13.7 5.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KFH45322.1 - 0.63 10.0 5.7 1.6 8.6 5.7 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_5 PF14634.6 KFH45322.1 - 2 8.4 8.9 4 7.5 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KFH45322.1 - 2.8 7.9 6.9 5.6 6.9 6.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KFH45322.1 - 6.6 6.6 7.8 2e+02 1.9 7.8 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFH45322.1 - 9.8 6.1 9.9 1.3 8.9 5.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 AAA PF00004.29 KFH45323.1 - 6.1e-51 172.3 0.0 1.9e-43 148.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH45323.1 - 0.00018 21.3 0.0 0.00064 19.5 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH45323.1 - 0.00059 20.3 5.4 0.016 15.6 0.0 4.1 4 1 1 5 5 4 1 AAA ATPase domain Parvo_NS1 PF01057.17 KFH45323.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KFH45323.1 - 0.0035 17.0 0.0 0.042 13.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KFH45323.1 - 0.0037 17.4 0.0 0.0086 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFH45323.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFH45323.1 - 0.0086 16.4 0.0 0.038 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFH45323.1 - 0.011 16.1 0.0 0.04 14.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 KFH45323.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KFH45323.1 - 0.027 13.8 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFH45323.1 - 0.03 14.3 0.0 0.13 12.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KFH45323.1 - 0.034 13.9 2.2 1.9 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA+ lid domain ATPase PF06745.13 KFH45323.1 - 0.039 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KFH45323.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH45323.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFH45323.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KFH45323.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 KFH45323.1 - 0.11 12.6 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TsaE PF02367.17 KFH45323.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFH45323.1 - 0.11 12.6 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Acid_PPase PF12689.7 KFH45324.1 - 1.1e-57 194.6 0.0 1.6e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase muHD PF10291.9 KFH45325.1 - 2.6e-61 207.4 0.0 3.8e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KFH45325.1 - 0.00019 21.7 0.1 0.00054 20.2 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Muted PF14942.6 KFH45325.1 - 0.0017 18.7 0.6 0.0017 18.7 0.6 1.9 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein BAR_3 PF16746.5 KFH45325.1 - 0.0041 16.9 1.2 0.0062 16.3 1.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Vps5 PF09325.10 KFH45325.1 - 0.005 16.4 0.2 0.005 16.4 0.2 1.5 2 0 0 2 2 2 1 Vps5 C terminal like Cys_Met_Meta_PP PF01053.20 KFH45325.1 - 0.055 12.0 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.18 KFH45325.1 - 0.36 10.5 3.0 0.56 9.8 3.0 1.2 1 0 0 1 1 1 0 BAR domain Trp_oprn_chp PF09534.10 KFH45327.1 - 1.9 8.3 11.1 1.5 8.6 1.2 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NUC153 PF08159.12 KFH45328.1 - 9.8e-15 54.1 19.0 2.8e-14 52.6 1.4 3.7 3 0 0 3 3 3 2 NUC153 domain DSPc PF00782.20 KFH45329.1 - 2.3e-10 40.4 0.0 4.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFH45329.1 - 0.00082 19.0 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFH45329.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family MAD PF05557.13 KFH45330.1 - 4e-69 233.7 61.4 9.1e-69 232.5 58.2 1.9 1 1 1 2 2 2 1 Mitotic checkpoint protein GAS PF13851.6 KFH45330.1 - 0.0033 16.8 7.5 0.0033 16.8 7.5 6.1 3 2 2 6 6 6 3 Growth-arrest specific micro-tubule binding DUF1850 PF08905.11 KFH45330.1 - 0.023 15.0 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1850) SSTK-IP PF15836.5 KFH45330.1 - 3.8 7.7 9.0 0.95 9.6 0.1 3.8 4 0 0 4 4 4 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Sad1_UNC PF07738.13 KFH45331.1 - 6e-06 26.3 0.0 0.0012 18.9 0.1 2.3 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal BMFP PF04380.13 KFH45331.1 - 0.29 11.6 1.5 2.1 8.9 0.8 2.7 1 1 1 2 2 2 0 Membrane fusogenic activity HD_3 PF13023.6 KFH45332.1 - 7e-50 169.2 0.0 8.9e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFH45332.1 - 1.4e-09 38.0 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Myb_DNA-binding PF00249.31 KFH45333.1 - 1.7e-09 37.7 0.0 6.7e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 KFH45333.1 - 6.2e-08 32.3 5.8 1.1e-07 31.5 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KFH45333.1 - 9.2e-08 32.3 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KFH45333.1 - 5.1e-06 26.6 0.3 1.3e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ECH_1 PF00378.20 KFH45334.1 - 7.8e-55 185.9 0.0 1.1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH45334.1 - 2.8e-27 96.1 0.0 3.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_zinc_N PF00107.26 KFH45335.1 - 8.6e-27 93.7 1.0 2.5e-26 92.2 0.1 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH45335.1 - 5.5e-17 63.1 0.0 1e-16 62.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH45335.1 - 4.5e-09 36.2 0.0 9.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFH45335.1 - 0.00045 20.1 0.0 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KFH45335.1 - 0.032 13.7 0.5 0.067 12.6 0.5 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ApbA PF02558.16 KFH45335.1 - 0.054 13.1 0.1 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA CoA_binding PF02629.19 KFH45336.1 - 7e-27 94.0 2.4 1.4e-26 93.0 0.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFH45336.1 - 5.1e-25 88.1 0.7 7.3e-25 87.6 0.7 1.2 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFH45336.1 - 1.7e-09 37.6 0.1 2.9e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFH45336.1 - 0.0034 17.9 0.3 0.016 15.7 0.0 2.2 2 1 1 3 3 3 1 CoA binding domain Cutinase PF01083.22 KFH45337.1 - 1e-24 87.4 0.0 2e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Cutinase FlxA PF14282.6 KFH45337.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 FlxA-like protein Prefoldin PF02996.17 KFH45337.1 - 0.025 14.5 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit SKA2 PF16740.5 KFH45337.1 - 0.037 13.8 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 PE-PPE PF08237.11 KFH45337.1 - 0.041 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain C8 PF08742.11 KFH45337.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 C8 domain DUF948 PF06103.11 KFH45337.1 - 0.15 12.3 0.5 0.32 11.3 0.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Noelin-1 PF12308.8 KFH45337.1 - 0.21 11.6 0.1 0.39 10.7 0.1 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein MFS_1 PF07690.16 KFH45339.1 - 7.2e-09 35.0 27.3 7.2e-09 35.0 27.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFH45339.1 - 5.3e-08 32.7 2.6 5.3e-08 32.7 2.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Mpv17_PMP22 PF04117.12 KFH45339.1 - 0.25 11.6 4.3 0.35 11.1 0.2 3.0 3 0 0 3 3 3 0 Mpv17 / PMP22 family Sulfatase PF00884.23 KFH45341.1 - 6.7e-58 196.5 1.6 8.3e-58 196.2 1.6 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFH45341.1 - 0.13 10.9 0.4 0.35 9.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) PurK_C PF17769.1 KFH45342.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Glyco_tran_WbsX PF14307.6 KFH45342.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase WbsX MFS_1 PF07690.16 KFH45343.1 - 8.2e-34 117.1 30.9 4.4e-24 85.1 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45343.1 - 9.2e-09 34.7 8.0 9.2e-09 34.7 8.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFH45343.1 - 0.00012 21.1 0.4 0.00012 21.1 0.4 3.1 2 1 1 3 3 3 2 MFS_1 like family TrkA_C PF02080.21 KFH45343.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain Ysc84 PF04366.12 KFH45344.1 - 1.4e-43 147.7 0.2 2.2e-43 147.0 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator TGT PF01702.18 KFH45344.1 - 0.21 10.7 0.1 0.34 10.0 0.1 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase DUF924 PF06041.11 KFH45345.1 - 3e-56 190.4 0.0 5.1e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Thioesterase PF00975.20 KFH45346.1 - 4.4e-15 56.4 0.0 7.2e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFH45346.1 - 1.2e-07 32.5 4.3 1.5e-07 32.2 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFH45346.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KFH45346.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family KR PF08659.10 KFH45346.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF2555 PF10742.9 KFH45346.1 - 0.16 11.8 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) SNF2_N PF00176.23 KFH45347.1 - 1.1e-64 218.4 0.7 2e-64 217.5 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFH45347.1 - 9.2e-47 158.8 15.9 9.2e-47 158.8 15.9 5.1 7 0 0 7 7 7 1 DNA-binding domain Helicase_C PF00271.31 KFH45347.1 - 2.5e-20 72.9 0.0 5.6e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH45347.1 - 4.7e-07 30.0 0.0 4.7e-07 30.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFH45347.1 - 0.024 13.8 5.8 0.09 11.9 0.0 3.5 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 KFH45347.1 - 0.53 9.9 3.6 0.21 11.2 0.8 1.7 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Ribosomal_S7e PF01251.18 KFH45348.1 - 4.4e-82 274.3 0.2 5.2e-82 274.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ABC2_membrane PF01061.24 KFH45349.1 - 2.7e-81 272.0 66.3 3e-42 144.4 25.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFH45349.1 - 3.9e-34 118.1 0.0 1.2e-17 64.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFH45349.1 - 4.4e-32 109.8 12.7 9.6e-29 99.1 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFH45349.1 - 1.4e-16 60.9 0.0 3.9e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFH45349.1 - 3.5e-06 27.5 0.1 0.00076 19.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFH45349.1 - 1.8e-05 24.9 0.1 0.0028 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFH45349.1 - 2.9e-05 24.0 0.1 0.0041 17.0 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KFH45349.1 - 8e-05 22.3 0.5 0.027 14.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFH45349.1 - 0.00012 21.7 0.6 0.0029 17.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH45349.1 - 0.0053 17.0 0.7 1 9.6 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFH45349.1 - 0.0055 16.6 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFH45349.1 - 0.0058 17.2 0.0 0.051 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KFH45349.1 - 0.013 14.6 59.5 0.076 12.1 27.9 4.3 2 2 1 3 3 3 0 ABC-2 family transporter protein cobW PF02492.19 KFH45349.1 - 0.013 15.0 2.3 0.072 12.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KFH45349.1 - 0.017 15.6 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFH45349.1 - 0.041 13.8 0.4 3 7.7 0.2 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KFH45349.1 - 0.057 13.5 0.2 15 5.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KFH45349.1 - 0.057 13.1 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KFH45349.1 - 0.12 11.8 0.0 1.3 8.5 0.0 2.5 2 2 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KFH45349.1 - 0.16 12.4 0.1 2.8 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KFH45350.1 - 0.0044 16.4 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFH45350.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4692 PF15763.5 KFH45350.1 - 0.16 12.5 0.9 0.28 11.6 0.9 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 KFH45350.1 - 1 9.0 8.3 1.5 8.4 8.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0052 PF01933.18 KFH45351.1 - 1.1e-64 218.5 0.0 1.5e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RNase_T PF00929.24 KFH45353.1 - 0.00064 20.3 0.1 0.0044 17.6 0.1 2.0 1 1 1 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFH45353.1 - 0.049 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease MFS_1 PF07690.16 KFH45354.1 - 4.9e-37 127.7 52.0 4.9e-36 124.4 49.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH45354.1 - 3e-10 39.2 30.5 4.3e-10 38.7 30.5 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cofilin_ADF PF00241.20 KFH45355.1 - 6.4e-38 129.3 0.0 1.3e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein P3A PF08727.11 KFH45355.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like PAP2 PF01569.21 KFH45356.1 - 1.8e-20 73.1 4.2 3.1e-20 72.3 4.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily AMP-binding PF00501.28 KFH45357.1 - 0 1008.5 0.0 1.6e-78 264.2 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KFH45357.1 - 9.8e-169 561.8 0.0 5.3e-45 153.9 0.0 5.4 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.25 KFH45357.1 - 2.3e-53 178.4 1.9 2e-13 50.5 0.0 6.0 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH45357.1 - 9.2e-07 29.8 0.0 0.21 12.6 0.0 4.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain BTAD PF03704.17 KFH45357.1 - 0.13 12.7 0.4 0.39 11.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain AAA PF00004.29 KFH45359.1 - 5.7e-41 140.0 0.0 1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFH45359.1 - 1.1e-11 44.5 0.3 2.2e-11 43.5 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFH45359.1 - 3.1e-11 42.9 0.6 5.7e-11 42.0 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KFH45359.1 - 3.2e-06 27.4 0.0 6.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFH45359.1 - 7.3e-06 26.3 0.1 0.022 15.0 0.1 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KFH45359.1 - 1.5e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFH45359.1 - 0.00018 21.5 0.1 0.00071 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFH45359.1 - 0.00035 20.4 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH45359.1 - 0.00042 20.8 0.1 0.0033 17.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 KFH45359.1 - 0.0017 17.9 0.4 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KFH45359.1 - 0.0022 18.2 0.3 0.0087 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFH45359.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFH45359.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFH45359.1 - 0.016 14.4 0.1 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 KFH45359.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KFH45359.1 - 0.023 14.2 1.6 0.48 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KFH45359.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KFH45359.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH45359.1 - 0.042 13.8 0.1 0.62 10.0 0.1 2.5 2 1 1 3 3 3 0 NACHT domain RNA_helicase PF00910.22 KFH45359.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KFH45359.1 - 0.059 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFH45359.1 - 0.06 12.7 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC RNA_pol_Rpb1_5 PF04998.17 KFH45359.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Zeta_toxin PF06414.12 KFH45359.1 - 0.087 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 KFH45359.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KFH45359.1 - 0.2 11.4 1.4 0.37 10.5 0.1 2.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KFH45359.1 - 0.5 9.9 3.7 0.62 9.6 0.4 2.6 2 1 1 3 3 3 0 AAA domain FAP PF07174.11 KFH45361.1 - 0.0099 15.4 2.2 0.011 15.2 2.2 1.0 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) zf-FPG_IleRS PF06827.14 KFH45361.1 - 0.033 14.0 1.1 0.033 14.0 1.1 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Mito_carr PF00153.27 KFH45362.1 - 9.8e-15 54.3 0.0 3.4e-08 33.3 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein FYVE PF01363.21 KFH45363.1 - 0.0081 16.3 8.4 0.0092 16.1 8.4 1.2 1 0 0 1 1 1 1 FYVE zinc finger ketoacyl-synt PF00109.26 KFH45364.1 - 1.7e-74 250.6 0.1 4.2e-74 249.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KFH45364.1 - 2.6e-71 240.5 0.0 7.1e-71 239.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KFH45364.1 - 2.6e-62 211.0 0.0 5.1e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 KFH45364.1 - 2.4e-55 188.3 0.0 4.4e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH45364.1 - 9.8e-53 178.7 0.2 5.5e-52 176.3 0.2 2.3 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KFH45364.1 - 9.5e-40 135.3 2.4 1.5e-39 134.7 0.8 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFH45364.1 - 1.8e-22 79.8 0.0 1e-21 77.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KFH45364.1 - 1.1e-18 67.4 0.2 5.3e-10 39.5 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFH45364.1 - 2.4e-15 57.0 0.0 1.4e-14 54.5 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KFH45364.1 - 1.5e-12 47.4 0.4 3e-12 46.4 0.4 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 KFH45364.1 - 4.7e-07 29.5 0.0 1.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase AMP-binding_C PF13193.6 KFH45364.1 - 4.6e-05 24.3 0.3 0.00022 22.2 0.0 2.4 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain SAT PF16073.5 KFH45364.1 - 0.0038 17.0 0.1 0.0085 15.8 0.1 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 KFH45364.1 - 0.028 13.9 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KFH45364.1 - 0.031 13.7 0.4 0.063 12.6 0.4 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KFH45364.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glu_dehyd_C PF16912.5 KFH45364.1 - 0.044 13.3 0.3 0.65 9.4 0.1 2.6 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Hva1_TUDOR PF11160.8 KFH45366.1 - 4.4e-19 68.4 0.5 5e-19 68.2 0.5 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain UQ_con PF00179.26 KFH45367.1 - 7.9e-43 145.5 0.0 1.7e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH45367.1 - 3.4e-08 33.2 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.10 KFH45367.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain LPMO_10 PF03067.15 KFH45368.1 - 1.7e-10 41.9 0.9 3.6e-10 40.8 0.9 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TcdB_N PF12918.7 KFH45370.1 - 0.23 11.8 0.6 0.33 11.3 0.2 1.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain adh_short PF00106.25 KFH45371.1 - 1.2e-38 132.5 0.0 1.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45371.1 - 4.6e-25 88.5 0.0 7.1e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH45371.1 - 3.8e-15 56.3 0.1 7.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH45371.1 - 0.027 13.9 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 KFH45372.1 - 4.9e-63 213.5 0.0 6.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gam PF06064.11 KFH45372.1 - 0.092 13.0 0.3 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Host-nuclease inhibitor protein Gam DUF3082 PF11282.8 KFH45373.1 - 0.13 12.5 0.1 0.13 12.5 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) DUF4419 PF14388.6 KFH45374.1 - 8.3e-104 347.2 0.0 9.7e-104 347.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_64 PF16483.5 KFH45377.1 - 2.2e-116 389.2 0.0 2.6e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase ATP-grasp_3 PF02655.14 KFH45378.1 - 9.4e-07 29.0 0.0 1.8e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain PikAIV_N PF18605.1 KFH45378.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain GMC_oxred_N PF00732.19 KFH45380.1 - 3.2e-49 167.9 0.0 4.3e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH45380.1 - 1.3e-32 113.3 0.0 2e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFH45380.1 - 1.2e-06 27.9 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH45380.1 - 1.5e-05 25.1 0.6 7.8e-05 22.8 0.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFH45380.1 - 2.5e-05 23.5 0.0 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KFH45380.1 - 0.00042 20.8 0.1 0.24 12.0 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH45380.1 - 0.0076 15.4 0.3 0.047 12.8 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KFH45380.1 - 0.014 15.0 5.6 0.11 12.0 5.6 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFH45380.1 - 0.039 12.8 0.1 0.09 11.6 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Dynactin_p62 PF05502.13 KFH45381.1 - 1.1e-196 654.3 4.0 2.8e-196 652.9 4.0 1.6 1 1 0 1 1 1 1 Dynactin p62 family p450 PF00067.22 KFH45382.1 - 9.6e-69 232.3 0.0 1.2e-68 231.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEM171 PF15471.6 KFH45383.1 - 0.11 11.5 4.1 0.13 11.2 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 ABC_tran PF00005.27 KFH45384.1 - 3.3e-45 154.0 0.0 2.1e-22 80.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFH45384.1 - 4.7e-20 71.4 0.5 4.7e-20 71.4 0.5 2.7 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KFH45384.1 - 3.3e-18 66.5 0.4 0.00019 21.4 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFH45384.1 - 1.2e-10 41.2 0.3 0.001 18.6 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH45384.1 - 1.7e-07 30.8 0.3 0.0025 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH45384.1 - 3.4e-06 27.7 5.5 0.036 14.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 KFH45384.1 - 7.8e-06 25.8 0.1 0.055 13.2 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 KFH45384.1 - 1.1e-05 25.9 0.1 0.0072 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFH45384.1 - 1.4e-05 25.1 0.2 0.0092 15.9 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 KFH45384.1 - 3.8e-05 24.1 0.0 0.45 10.9 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KFH45384.1 - 4.5e-05 23.5 0.0 0.026 14.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFH45384.1 - 5.7e-05 23.3 0.1 0.66 10.1 0.1 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KFH45384.1 - 7e-05 22.8 0.1 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KFH45384.1 - 0.00012 22.3 0.1 0.11 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFH45384.1 - 0.00012 22.6 0.0 0.17 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFH45384.1 - 0.00028 20.9 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFH45384.1 - 0.00044 20.6 0.9 1.2 9.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_24 PF13479.6 KFH45384.1 - 0.00072 19.3 1.0 2 8.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 KFH45384.1 - 0.0012 19.1 0.1 0.46 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFH45384.1 - 0.0013 18.8 0.4 1.7 8.6 0.0 3.5 3 1 1 4 4 4 1 Dynamin family AAA_17 PF13207.6 KFH45384.1 - 0.0023 18.3 0.0 0.57 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFH45384.1 - 0.003 17.6 0.0 3.1 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KFH45384.1 - 0.0037 16.9 0.0 0.97 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFH45384.1 - 0.0042 16.7 0.1 0.72 9.4 0.1 3.1 3 1 0 3 3 2 1 AAA domain Roc PF08477.13 KFH45384.1 - 0.0049 17.1 0.1 3.3 8.0 0.1 3.0 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KFH45384.1 - 0.012 14.7 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 KFH45384.1 - 0.026 14.1 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KFH45384.1 - 0.029 13.6 0.0 4.6 6.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 KFH45384.1 - 0.045 13.7 0.4 2.3 8.1 0.3 2.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KFH45384.1 - 0.07 13.2 0.2 16 5.5 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KFH45384.1 - 0.079 12.7 1.5 2 8.1 0.1 3.2 4 1 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 KFH45384.1 - 0.09 12.4 0.0 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KFH45384.1 - 0.1 12.8 1.3 16 5.8 0.1 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 KFH45384.1 - 0.11 12.5 0.2 28 4.7 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GFA PF04828.14 KFH45385.1 - 1.9e-08 34.5 0.6 1.9e-08 34.5 0.6 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_72 PF03198.14 KFH45386.1 - 1.8e-117 392.1 3.1 2.3e-117 391.8 3.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KFH45386.1 - 1.9e-21 76.5 1.8 4.8e-21 75.2 1.8 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KFH45386.1 - 1.8e-07 30.6 0.7 6.5e-07 28.8 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KFH45386.1 - 0.00027 20.5 0.4 0.0065 15.9 0.4 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPF0258 PF06789.12 KFH45386.1 - 0.13 12.3 0.2 0.96 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Mito_carr PF00153.27 KFH45387.1 - 1.1e-67 224.0 1.7 1.6e-21 76.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KFH45388.1 - 5.1e-50 170.6 0.0 6.7e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KFH45388.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 PIG-X / PBN1 Amidohydro_1 PF01979.20 KFH45389.1 - 2.8e-63 214.3 0.0 3.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH45389.1 - 6.2e-12 45.7 0.2 5.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KFH45389.1 - 0.017 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Bcl-2_3 PF15286.6 KFH45390.1 - 0.092 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Promethin PF16015.5 KFH45391.1 - 1.1e-32 112.1 16.5 1.4e-32 111.8 16.5 1.1 1 0 0 1 1 1 1 Promethin Peptidase_U4 PF03419.13 KFH45391.1 - 0.3 10.4 2.7 0.32 10.2 2.7 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ADH_zinc_N PF00107.26 KFH45392.1 - 4.8e-29 101.0 1.9 5.6e-29 100.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH45392.1 - 1.9e-18 67.8 0.0 6.9e-18 66.0 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH45392.1 - 7.6e-08 32.2 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFH45392.1 - 6.9e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 KFH45392.1 - 0.0018 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ketoacyl-synt PF00109.26 KFH45393.1 - 2.9e-64 217.1 0.2 1.7e-63 214.6 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFH45393.1 - 2e-62 211.1 0.0 3.4e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH45393.1 - 1.6e-61 208.6 0.9 3.2e-61 207.6 0.9 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH45393.1 - 1.4e-56 191.3 1.3 3.4e-56 190.0 1.3 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFH45393.1 - 6.7e-32 110.0 0.1 1.8e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH45393.1 - 3e-20 72.8 0.0 1.2e-19 70.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH45393.1 - 2.6e-18 66.5 0.2 1.1e-17 64.5 0.2 2.2 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KFH45393.1 - 2.7e-17 64.1 0.0 2.9e-16 60.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH45393.1 - 3.2e-13 49.8 0.1 1e-12 48.2 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KFH45393.1 - 7.5e-12 45.8 0.0 2.8e-11 44.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFH45393.1 - 3.7e-10 40.0 0.3 1e-09 38.6 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KFH45393.1 - 7.6e-10 39.3 0.0 2.2e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH45393.1 - 8e-10 38.8 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45393.1 - 9.7e-09 35.2 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH45393.1 - 3.4e-07 29.9 0.4 1.1e-06 28.3 0.4 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 KFH45393.1 - 1.2e-05 24.8 0.8 0.00052 19.5 0.0 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain NodS PF05401.11 KFH45393.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) ADH_N PF08240.12 KFH45393.1 - 2.1e-05 24.3 0.2 9.7e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KFH45393.1 - 0.00033 20.1 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KFH45393.1 - 0.0022 17.8 0.2 0.006 16.4 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_28 PF02636.17 KFH45393.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KFH45393.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase ADH_N_2 PF16884.5 KFH45393.1 - 0.024 14.5 0.0 6.7 6.7 0.0 3.5 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase SAT PF16073.5 KFH45393.1 - 0.087 12.5 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_33 PF10017.9 KFH45393.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 KFH45395.1 - 6.9e-25 87.7 28.7 6.9e-25 87.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KFH45396.1 - 1e-10 41.0 0.7 2.8e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45396.1 - 1.1e-05 25.5 8.9 1.7e-05 24.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KFH45397.1 - 7.8e-13 48.9 0.0 1.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Chromo_shadow PF01393.19 KFH45398.1 - 1.1e-19 70.2 3.3 5.4e-18 64.8 0.3 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFH45398.1 - 3.3e-11 42.9 1.5 3.3e-11 42.9 1.5 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 KFH45398.1 - 0.16 11.9 5.1 0.65 10.1 5.1 2.1 1 0 0 1 1 1 0 AT hook motif ELM2 PF01448.24 KFH45398.1 - 1.3 9.9 4.3 3.2 8.6 2.5 2.4 2 1 0 2 2 2 0 ELM2 domain ABC1 PF03109.16 KFH45399.1 - 2.3e-22 79.4 0.0 1.9e-13 50.6 0.0 2.7 2 1 1 3 3 3 2 ABC1 family APH PF01636.23 KFH45399.1 - 0.094 12.6 0.1 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family POTRA_TamA_1 PF17243.2 KFH45399.1 - 0.21 11.7 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DUF2204 PF09970.9 KFH45401.1 - 0.00068 19.3 0.0 0.00086 19.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) UQ_con PF00179.26 KFH45402.1 - 1.4e-20 73.3 0.0 2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH45402.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Response_reg PF00072.24 KFH45403.1 - 9.6e-14 51.5 0.1 2.5e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFH45403.1 - 1.1e-07 31.8 0.0 5.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 KFH45403.1 - 0.0018 18.7 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DbpA PF03880.15 KFH45404.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Bap31_Bap29_C PF18035.1 KFH45405.1 - 0.4 10.7 3.5 0.17 11.9 0.6 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3450 PF11932.8 KFH45405.1 - 1.1 8.5 4.5 0.21 10.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KFH45405.1 - 4.1 7.9 9.3 0.7 10.4 2.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB CCDC85 PF10226.9 KFH45405.1 - 7.9 6.1 9.8 0.41 10.3 1.8 2.5 2 2 0 2 2 2 0 CCDC85 family Acetyltransf_1 PF00583.25 KFH45407.1 - 1.3e-06 28.6 0.0 9.5e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH45407.1 - 2.4e-05 24.7 0.0 0.00073 19.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFH45407.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH45407.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH45407.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KFH45407.1 - 0.27 11.4 0.0 0.64 10.1 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2613 PF11021.8 KFH45408.1 - 0.019 15.1 1.3 0.036 14.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) TMEM51 PF15345.6 KFH45408.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.10 KFH45408.1 - 0.087 12.2 6.5 0.16 11.4 6.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CFEM PF05730.11 KFH45408.1 - 0.1 12.7 17.7 0.29 11.3 3.0 3.4 3 0 0 3 3 3 0 CFEM domain ABC2_membrane PF01061.24 KFH45409.1 - 7.9e-92 306.4 49.7 2.7e-49 167.4 23.1 3.3 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KFH45409.1 - 3.8e-36 122.9 8.9 1.3e-33 114.7 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KFH45409.1 - 1.7e-32 112.8 0.0 1.5e-16 61.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KFH45409.1 - 3.6e-17 62.8 0.1 8.6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFH45409.1 - 2.3e-07 31.4 0.0 0.00023 21.6 0.1 3.0 4 0 0 4 4 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFH45409.1 - 3.7e-06 26.9 0.1 0.00038 20.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFH45409.1 - 9.3e-05 22.1 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFH45409.1 - 0.00018 21.5 0.1 0.63 9.8 0.0 3.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH45409.1 - 0.00022 20.9 0.5 0.037 13.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFH45409.1 - 0.00027 21.5 0.0 0.065 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH45409.1 - 0.00029 21.0 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH45409.1 - 0.0014 18.9 0.1 0.3 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFH45409.1 - 0.0034 17.0 0.3 0.063 12.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFH45409.1 - 0.0051 16.7 0.1 2.2 8.2 0.2 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 KFH45409.1 - 0.0099 16.3 0.3 4.5 7.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFH45409.1 - 0.045 14.2 0.0 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFH45409.1 - 0.054 13.2 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFH45409.1 - 0.074 13.5 0.1 0.2 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain SMC_N PF02463.19 KFH45409.1 - 0.082 12.3 0.0 9 5.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 KFH45409.1 - 0.087 13.2 0.1 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase HalX PF08663.10 KFH45409.1 - 0.12 12.7 0.1 23 5.4 0.0 2.4 2 0 0 2 2 2 0 HalX domain ABC2_membrane_3 PF12698.7 KFH45409.1 - 0.59 9.2 48.3 0.038 13.1 18.6 3.4 2 2 1 3 3 3 0 ABC-2 family transporter protein APH PF01636.23 KFH45410.1 - 3.7e-11 43.4 0.1 8.8e-11 42.2 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KFH45411.1 - 7.6e-59 199.1 0.1 9.1e-59 198.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH45411.1 - 3.9e-45 153.7 0.6 4.5e-45 153.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45411.1 - 3.4e-11 43.4 0.2 5e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH45411.1 - 0.0025 17.3 0.1 0.0059 16.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Inv-AAD PF18785.1 KFH45412.1 - 9.7e-59 196.9 0.2 1.1e-58 196.6 0.2 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KFH45412.1 - 3e-12 46.3 0.1 4.1e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KFH45412.1 - 0.0012 18.7 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APH PF01636.23 KFH45413.1 - 6.8e-07 29.4 0.0 8.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family HD PF01966.22 KFH45414.1 - 1.6e-06 28.4 0.2 2.7e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 HD domain Stn1 PF10451.9 KFH45415.1 - 4.7e-13 48.7 4.1 6.2e-06 25.4 0.4 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KFH45415.1 - 0.00066 19.6 0.1 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFH45415.1 - 0.0011 18.7 0.1 1.7 8.4 0.0 2.8 3 0 0 3 3 3 2 RecQ-mediated genome instability protein 2 Kre28 PF17097.5 KFH45415.1 - 0.036 13.0 1.1 0.047 12.7 1.1 1.1 1 0 0 1 1 1 0 Spindle pole body component Na_Ca_ex PF01699.24 KFH45419.1 - 9e-43 145.8 37.6 3.5e-22 79.0 17.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zn_clus PF00172.18 KFH45420.1 - 2.2e-09 37.3 8.7 3.9e-09 36.5 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH45420.1 - 0.00012 21.2 0.0 0.00028 20.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KFH45421.1 - 6.9e-54 179.8 4.2 5.2e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX7C PF02935.16 KFH45421.1 - 0.07 13.4 0.3 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc COX15-CtaA PF02628.15 KFH45422.1 - 3.8e-111 371.3 6.8 4.8e-111 370.9 6.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3439 PF11921.8 KFH45422.1 - 0.26 11.3 6.5 0.65 10.0 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_67M PF07488.12 KFH45423.1 - 1.1e-144 481.5 0.0 1.5e-144 481.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KFH45423.1 - 1.6e-85 286.2 1.9 2.5e-85 285.6 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KFH45423.1 - 2.9e-29 101.9 0.0 5.3e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KFH45423.1 - 0.0026 18.5 0.1 0.007 17.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RRM_1 PF00076.22 KFH45424.1 - 1.8e-07 30.9 0.1 3.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH45424.1 - 0.00028 20.8 0.0 0.00071 19.5 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFH45424.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif AGOG PF09171.10 KFH45424.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Glyco_hydro_127 PF07944.12 KFH45425.1 - 0.17 10.4 0.0 0.26 9.7 0.0 1.3 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 BUD22 PF09073.10 KFH45426.1 - 9.9e-108 361.2 31.9 1.2e-107 361.0 31.9 1.0 1 0 0 1 1 1 1 BUD22 EVC2_like PF12297.8 KFH45426.1 - 1.4 7.6 5.3 2.2 6.9 5.3 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4724 PF15852.5 KFH45426.1 - 4.8 7.7 6.3 2.1 8.9 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) ETX_MTX2 PF03318.13 KFH45427.1 - 0.004 17.0 4.2 0.0079 16.0 4.2 1.5 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 FA_hydroxylase PF04116.13 KFH45428.1 - 9.1e-21 74.6 14.8 9.1e-21 74.6 14.8 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PapC_C PF13953.6 KFH45428.1 - 0.0032 17.3 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 PapC C-terminal domain ParA PF10609.9 KFH45429.1 - 1.7e-94 315.9 0.0 2e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFH45429.1 - 3.5e-11 43.2 0.0 1.1e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFH45429.1 - 4.1e-09 36.6 0.2 4.7e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFH45429.1 - 0.00018 20.9 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFH45429.1 - 0.0016 17.7 0.2 0.029 13.5 0.0 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFH45429.1 - 0.0031 17.0 0.0 0.14 11.6 0.0 2.3 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KFH45429.1 - 0.0054 16.6 0.3 0.2 11.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KFH45429.1 - 0.012 15.2 0.7 0.085 12.3 0.3 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KFH45429.1 - 0.015 14.9 0.6 0.03 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_S27e PF01667.17 KFH45429.1 - 0.17 11.6 0.2 0.44 10.3 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S27 Glyoxalase_6 PF18029.1 KFH45431.1 - 0.074 13.8 1.3 0.15 12.9 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain Collagen_mid PF15984.5 KFH45432.1 - 0.052 13.3 0.8 0.59 9.9 0.0 2.0 1 1 1 2 2 2 0 Bacterial collagen, middle region Apolipoprotein PF01442.18 KFH45432.1 - 0.057 13.3 0.4 0.32 10.8 0.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IFT57 PF10498.9 KFH45432.1 - 0.092 11.7 0.1 0.2 10.6 0.1 1.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 KFH45432.1 - 0.12 12.7 0.1 1.8 9.0 0.0 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFH45432.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cyto_heme_lyase PF01265.17 KFH45433.1 - 1.2e-124 415.7 0.2 1.4e-124 415.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans PF04082.18 KFH45434.1 - 3.8e-12 45.8 0.4 9.9e-12 44.4 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45434.1 - 1.4e-06 28.3 7.2 2.6e-06 27.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KFH45434.1 - 4.6 7.8 9.4 38 4.9 2.2 2.5 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Bac_surface_Ag PF01103.23 KFH45435.1 - 2e-35 122.9 0.1 2.5e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KFH45435.1 - 0.026 14.0 0.5 4.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Peptidase_M28 PF04389.17 KFH45436.1 - 2.2e-33 115.7 0.0 3.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH45436.1 - 5.5e-12 45.5 0.2 1.1e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFH45436.1 - 0.00046 19.9 0.0 0.00094 18.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2680 PF10925.8 KFH45436.1 - 0.026 14.5 0.3 0.056 13.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) HgmA PF04209.13 KFH45438.1 - 1e-190 633.9 0.0 1.2e-190 633.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Vint PF14623.6 KFH45439.1 - 4.5e-62 208.8 0.0 7.3e-62 208.1 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KFH45439.1 - 8.2e-27 93.1 0.0 1.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KFH45439.1 - 1.1e-17 64.8 0.0 6.5e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFH45439.1 - 2.9e-15 56.8 0.0 5.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFH45439.1 - 2e-12 47.3 0.0 2.1e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain AlaE PF06610.13 KFH45439.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 L-alanine exporter Hint PF01079.20 KFH45439.1 - 0.17 11.3 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 Hint module LRR_4 PF12799.7 KFH45440.1 - 4.3e-27 93.7 36.3 2.5e-05 24.5 1.2 9.6 6 3 4 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH45440.1 - 2.1e-26 91.4 40.5 4.8e-06 26.2 0.1 8.5 4 3 7 12 12 12 11 Leucine rich repeat LRR_9 PF14580.6 KFH45440.1 - 0.0013 18.3 19.8 0.11 12.0 0.5 4.9 3 2 2 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 KFH45440.1 - 0.066 13.8 28.2 3.4 8.6 0.0 10.2 12 2 0 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 KFH45440.1 - 2 8.7 27.4 3.7 7.9 0.0 9.0 11 0 0 11 11 11 0 Leucine Rich repeat Aminotran_3 PF00202.21 KFH45441.1 - 9.6e-81 271.5 0.0 1.2e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HET PF06985.11 KFH45443.1 - 4.3e-29 101.7 3.0 6.7e-29 101.1 3.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhoR PF11808.8 KFH45443.1 - 0.046 14.1 1.0 0.11 12.9 1.0 1.6 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR APH PF01636.23 KFH45444.1 - 1.9e-14 54.2 0.1 4.1e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family bPH_4 PF06713.11 KFH45444.1 - 0.00047 20.2 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Choline_kinase PF01633.20 KFH45444.1 - 0.0043 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DnaJ PF00226.31 KFH45446.1 - 4.6e-23 81.1 3.3 1.5e-22 79.5 3.3 2.0 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 KFH45446.1 - 0.0082 16.4 0.9 3.1 8.2 0.0 3.9 3 1 0 3 3 3 1 Nif11 domain PRTP PF01366.18 KFH45446.1 - 0.27 9.2 1.7 0.38 8.7 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein PNPase PF03726.14 KFH45446.1 - 9.6 6.8 10.7 18 5.9 0.1 3.7 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF2293 PF10056.9 KFH45447.1 - 4.6e-25 87.7 0.1 1e-24 86.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_hydro81C PF17652.1 KFH45449.1 - 5e-158 525.9 2.3 6.4e-158 525.5 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KFH45449.1 - 1e-113 379.8 0.8 1.3e-113 379.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain CsbD PF05532.12 KFH45449.1 - 0.087 12.7 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 CsbD-like DEC-1_N PF04625.13 KFH45450.1 - 8.3 5.3 14.2 15 4.5 14.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Utp14 PF04615.13 KFH45451.1 - 2.9e-186 621.4 62.7 2.9e-186 621.4 62.7 2.2 1 1 1 2 2 2 1 Utp14 protein UPF0767 PF15990.5 KFH45451.1 - 2 8.6 3.9 9.6 6.4 3.9 2.2 1 0 0 1 1 1 0 UPF0767 family Germane PF10646.9 KFH45453.1 - 0.11 13.3 0.0 1.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Sporulation and spore germination adh_short_C2 PF13561.6 KFH45454.1 - 6.4e-36 124.1 0.0 1.2e-34 119.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH45454.1 - 1.5e-34 119.2 0.0 2.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45454.1 - 3.8e-09 36.7 0.1 1.3e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KFH45454.1 - 0.0044 17.3 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFH45454.1 - 0.03 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KFH45454.1 - 0.061 13.9 0.1 0.11 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 KFH45454.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-Di19 PF05605.12 KFH45455.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding YabA PF06156.13 KFH45455.1 - 0.025 15.2 2.2 0.046 14.3 0.5 2.4 2 0 0 2 2 2 0 Initiation control protein YabA zf-C2H2_4 PF13894.6 KFH45455.1 - 0.037 14.9 0.1 0.098 13.6 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFH45455.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FlpD PF02662.16 KFH45455.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit zf-C2H2 PF00096.26 KFH45455.1 - 0.086 13.3 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KFH45455.1 - 0.16 11.4 0.4 0.33 10.4 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HALZ PF02183.18 KFH45455.1 - 1.4 9.2 8.1 1.8 8.9 4.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 KFH45455.1 - 8 5.4 16.4 36 3.3 16.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chibby PF14645.6 KFH45455.1 - 8.7 6.8 9.2 0.27 11.7 1.1 2.6 3 0 0 3 3 3 0 Chibby family Fungal_trans PF04082.18 KFH45456.1 - 4.2e-12 45.7 0.0 9.2e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45456.1 - 8.5e-05 22.6 10.9 0.00015 21.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_ImportDeg PF09783.9 KFH45456.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.5 1 1 0 1 1 1 0 Vacuolar import and degradation protein ArAE_1_C PF11728.8 KFH45456.1 - 0.11 12.4 0.7 0.27 11.2 0.2 1.9 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain TRAUB PF08164.12 KFH45457.1 - 2.5e-29 101.6 0.1 2.5e-29 101.6 0.1 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KFH45457.1 - 1.7e-26 93.6 0.4 1.7e-26 93.6 0.4 3.3 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor SRC-1 PF08832.10 KFH45457.1 - 3 9.0 6.4 15 6.7 0.9 3.3 3 0 0 3 3 3 0 Steroid receptor coactivator DUF2207 PF09972.9 KFH45459.1 - 0.39 9.4 3.2 0.4 9.4 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tudor_3 PF18115.1 KFH45460.1 - 4.4e-07 29.6 0.0 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 KFH45460.1 - 0.0027 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 KFH45460.1 - 0.0098 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KFH45460.1 - 0.021 14.9 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain IL11 PF07400.11 KFH45460.1 - 0.11 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Interleukin 11 FlxA PF14282.6 KFH45460.1 - 0.16 11.9 3.9 0.36 10.9 3.9 1.5 1 0 0 1 1 1 0 FlxA-like protein SH3_1 PF00018.28 KFH45461.1 - 3.7e-09 36.0 0.0 6.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFH45461.1 - 9.2e-08 31.8 0.1 1.9e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH45461.1 - 8.1e-06 25.4 0.0 9.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain MARVEL PF01284.23 KFH45462.1 - 0.00087 19.3 25.1 0.006 16.6 24.6 2.1 1 1 0 1 1 1 1 Membrane-associating domain PulG PF11773.8 KFH45462.1 - 0.034 14.0 0.7 0.43 10.4 0.0 2.8 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin FixP_N PF14715.6 KFH45462.1 - 0.16 11.7 3.0 0.48 10.2 3.0 1.8 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP CD20 PF04103.15 KFH45462.1 - 5 7.2 17.3 25 4.9 17.3 2.2 1 1 0 1 1 1 0 CD20-like family DUF1479 PF07350.12 KFH45463.1 - 8e-127 423.4 0.0 9.3e-127 423.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) TauD PF02668.16 KFH45463.1 - 0.052 13.3 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family tRNA-synt_2c PF01411.19 KFH45464.1 - 9e-212 704.4 0.0 1.4e-211 703.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFH45464.1 - 3.4e-18 65.4 0.1 1.3e-17 63.6 0.1 2.1 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFH45464.1 - 1.6e-09 38.3 2.0 6.4e-09 36.3 2.0 2.2 1 0 0 1 1 1 1 DHHA1 domain HAD_2 PF13419.6 KFH45464.1 - 3.1 7.8 5.0 4.7 7.3 1.4 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Enkurin PF13864.6 KFH45464.1 - 7.5 7.1 10.1 0.79 10.2 4.4 2.2 2 0 0 2 2 2 0 Calmodulin-binding TFIIS_M PF07500.14 KFH45465.1 - 3.7e-27 95.0 0.9 3.7e-27 95.0 0.9 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFH45465.1 - 2.1e-16 59.5 8.1 3.3e-16 58.9 8.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFH45465.1 - 3.4e-11 43.0 1.6 6.8e-11 42.0 0.7 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Cytochrom_NNT PF03264.14 KFH45465.1 - 0.018 14.7 3.8 0.041 13.6 3.8 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Hus1 PF04005.12 KFH45465.1 - 0.04 13.0 0.5 0.064 12.4 0.5 1.3 1 0 0 1 1 1 0 Hus1-like protein MIF4G_like_2 PF09090.11 KFH45465.1 - 2.1 7.7 6.0 0.55 9.7 0.1 2.4 2 1 1 3 3 3 0 MIF4G like Sgf11 PF08209.11 KFH45465.1 - 2.3 7.9 5.4 1.5 8.4 1.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Dynein_light PF01221.18 KFH45466.1 - 1.8e-35 121.1 2.1 2.8e-35 120.5 2.1 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 GIT_SHD PF08518.11 KFH45467.1 - 5.9e-24 83.4 6.6 9.7e-14 50.7 1.2 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF1843 PF08898.10 KFH45467.1 - 0.015 15.8 0.2 0.053 14.0 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) B12-binding PF02310.19 KFH45467.1 - 0.016 15.2 0.2 0.06 13.4 0.1 1.9 2 0 0 2 2 2 0 B12 binding domain FUSC PF04632.12 KFH45467.1 - 1.4 7.4 8.6 2.2 6.7 8.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KFH45467.1 - 2.7 8.4 35.0 0.1 13.0 22.6 2.5 1 1 1 2 2 2 0 Fez1 Macoilin PF09726.9 KFH45467.1 - 5.6 5.4 21.8 11 4.5 21.8 1.3 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 KFH45468.1 - 0.43 10.4 10.4 0.64 9.9 10.4 1.2 1 0 0 1 1 1 0 SPX domain LSM PF01423.22 KFH45469.1 - 3.5e-13 49.0 0.0 4.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFH45469.1 - 0.0024 18.0 0.0 0.004 17.3 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain ADH_N PF08240.12 KFH45470.1 - 6.8e-23 80.6 0.7 1.4e-22 79.6 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KFH45470.1 - 1.6e-08 34.3 0.3 5.3e-08 32.6 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KFH45470.1 - 2e-08 34.3 0.1 2.3e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KFH45470.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HDC PF02329.16 KFH45470.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain Plk4_PB2 PF18409.1 KFH45471.1 - 0.52 11.0 5.1 0.34 11.6 0.2 3.0 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 APH PF01636.23 KFH45472.1 - 0.034 14.1 0.9 0.39 10.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UDG PF03167.19 KFH45473.1 - 2e-22 79.9 0.1 4.2e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ezh2_MCSS PF18600.1 KFH45474.1 - 2.1e-19 68.8 1.2 2.1e-19 68.8 1.2 1.9 2 0 0 2 2 2 1 MCSS domain EZH2_N PF18601.1 KFH45474.1 - 3.2e-15 56.2 0.2 7.5e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 EZH2 N-terminal domain SET PF00856.28 KFH45474.1 - 4.5e-12 46.7 0.2 4.5e-12 46.7 0.2 4.4 3 2 0 3 3 3 1 SET domain preSET_CXC PF18264.1 KFH45474.1 - 1.8e-06 28.3 13.8 1.8e-06 28.3 13.8 3.4 3 1 0 3 3 3 1 CXC domain DUF1713 PF08213.11 KFH45475.1 - 5.5e-09 35.8 21.0 5.5e-09 35.8 21.0 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KFH45475.1 - 0.026 15.2 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial protein Pet20 HHH PF00633.23 KFH45477.1 - 0.049 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF726 PF05277.12 KFH45478.1 - 4.5e-115 384.2 0.2 5.8e-115 383.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KFH45478.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFH45478.1 - 0.09 13.4 2.2 0.096 13.3 0.2 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_92 PF07971.12 KFH45479.1 - 1.9e-145 485.4 0.0 2.5e-145 485.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFH45479.1 - 5.9e-71 239.1 0.4 8.6e-71 238.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain PAF-AH_p_II PF03403.13 KFH45480.1 - 6.9e-05 21.5 0.0 0.0031 16.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KFH45480.1 - 0.00025 21.7 11.9 0.0011 19.6 11.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH45480.1 - 0.0018 17.6 0.1 0.0085 15.4 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFH45480.1 - 0.044 13.3 0.2 0.11 11.9 0.2 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 KFH45480.1 - 0.071 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thg1C PF14413.6 KFH45481.1 - 2.5e-50 169.7 0.5 3.5e-50 169.3 0.5 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KFH45481.1 - 3.5e-27 94.9 0.0 6.2e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase MFS_1 PF07690.16 KFH45482.1 - 3.6e-40 138.0 29.2 2.5e-28 99.0 5.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45482.1 - 4.8e-09 35.6 5.6 4.8e-09 35.6 5.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFH45482.1 - 3.5e-05 22.8 8.6 0.018 13.9 0.6 2.2 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KFH45482.1 - 0.012 14.1 0.5 0.019 13.4 0.5 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4448 PF14610.6 KFH45483.1 - 2.1e-33 115.7 0.0 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) WD40 PF00400.32 KFH45484.1 - 3.2e-09 37.3 4.2 0.062 14.2 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45484.1 - 0.0075 16.5 2.0 13 6.2 0.1 5.1 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KFH45484.1 - 0.29 11.1 1.2 5 7.2 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat DHDPS PF00701.22 KFH45485.1 - 1e-39 136.0 0.0 1.3e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PALP PF00291.25 KFH45486.1 - 7.6e-64 215.9 0.7 9.2e-64 215.7 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.26 KFH45486.1 - 0.069 13.3 0.2 6.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain APH PF01636.23 KFH45487.1 - 1.1e-14 55.0 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH45487.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFH45487.1 - 0.0076 15.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family HSP70 PF00012.20 KFH45490.1 - 2e-186 620.8 3.3 2.2e-186 620.6 3.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFH45490.1 - 5.7e-15 54.9 0.2 1e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KFH45490.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1464 PF07318.12 KFH45490.1 - 0.017 14.3 0.6 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Velvet PF11754.8 KFH45491.1 - 0.98 9.3 6.6 4.8 7.0 6.6 1.9 1 1 0 1 1 1 0 Velvet factor Presenilin PF01080.17 KFH45491.1 - 2.4 6.8 6.1 3.6 6.2 6.1 1.3 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KFH45491.1 - 4.7 7.6 11.2 2.9 8.3 7.8 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAD_binding_4 PF01565.23 KFH45492.1 - 2.7e-31 108.2 2.4 5.4e-31 107.2 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH45492.1 - 1.7e-10 40.9 0.1 3.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_12 PF01670.16 KFH45494.1 - 1.6e-17 64.3 0.2 1.6e-17 64.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 adh_short_C2 PF13561.6 KFH45495.1 - 5.8e-52 176.6 0.1 7e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH45495.1 - 6.1e-40 136.8 0.0 7.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45495.1 - 3.9e-17 62.7 0.1 5.2e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH45495.1 - 1.8e-06 27.6 0.0 2.6e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH45495.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFH45495.1 - 0.0028 16.8 0.2 0.0038 16.4 0.2 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain RNA_pol_Rpb1_1 PF04997.12 KFH45497.1 - 8.9e-109 363.6 0.0 1.3e-108 363.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFH45497.1 - 5.5e-99 330.9 0.0 8.6e-99 330.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFH45497.1 - 7.1e-77 257.3 0.0 1.3e-76 256.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KFH45497.1 - 8.7e-61 205.1 0.9 1.5e-60 204.4 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KFH45497.1 - 3.1e-48 163.2 7.2 8.4e-48 161.8 7.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KFH45497.1 - 1e-45 155.5 0.0 2.3e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFH45497.1 - 8.7e-36 122.2 0.1 2.2e-35 120.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KFH45497.1 - 1.2e-06 28.5 179.5 0.0054 17.0 9.3 12.2 9 3 2 12 12 12 7 RNA polymerase Rpb1 C-terminal repeat RRM_1 PF00076.22 KFH45498.1 - 5.7e-73 240.7 0.5 4.1e-19 68.2 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH45498.1 - 7.4e-10 38.6 0.0 0.0016 18.3 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFH45498.1 - 3.7e-06 26.9 0.3 0.63 10.1 0.0 4.5 5 0 0 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFH45498.1 - 6.1e-06 26.1 0.0 2.8 8.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFH45498.1 - 2.2e-05 24.5 0.0 6.1 7.0 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif Limkain-b1 PF11608.8 KFH45498.1 - 0.00023 21.2 0.1 1.4 9.1 0.0 4.8 6 0 0 6 6 6 1 Limkain b1 RRM_5 PF13893.6 KFH45498.1 - 0.00031 20.3 0.0 3.7 7.1 0.0 4.1 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 KFH45498.1 - 0.081 12.9 0.2 4.3 7.3 0.0 3.5 4 0 0 4 4 4 0 Smg-4/UPF3 family NAD_binding_1 PF00175.21 KFH45499.1 - 1.6e-31 109.2 0.0 3.2e-31 108.2 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFH45499.1 - 6.4e-24 84.2 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFH45499.1 - 1.2e-08 35.2 0.0 0.00056 20.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain TFR_dimer PF04253.15 KFH45502.1 - 1.6e-26 92.8 0.0 2.9e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFH45502.1 - 4.6e-21 75.4 0.0 7.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH45502.1 - 2.2e-09 37.2 0.8 6.1e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KFH45502.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Sel1 PF08238.12 KFH45503.1 - 1.1e-30 105.4 38.8 0.00038 21.1 0.0 12.2 12 1 0 12 12 12 8 Sel1 repeat TPR_12 PF13424.6 KFH45503.1 - 9.1 6.7 8.6 5.4 7.4 0.2 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat XPG_N PF00752.17 KFH45504.1 - 1.8e-32 111.8 0.0 4e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFH45504.1 - 4.6e-27 94.2 0.0 1.7e-26 92.4 0.0 2.1 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KFH45504.1 - 0.011 15.6 2.2 0.011 15.6 2.2 4.1 4 0 0 4 4 4 0 Ubiquitin interaction motif DUF1943 PF09172.11 KFH45504.1 - 0.018 14.3 0.1 0.041 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Ssu72 PF04722.13 KFH45505.1 - 2.6e-84 281.6 0.0 3e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Pil1 PF13805.6 KFH45506.1 - 3.2e-125 417.0 0.2 4e-125 416.6 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KFH45506.1 - 0.048 13.1 1.8 0.1 12.0 1.8 1.6 1 1 0 1 1 1 0 FAM92 protein Octopine_DH PF02317.17 KFH45506.1 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Atg14 PF10186.9 KFH45506.1 - 1.2 8.2 6.9 1.5 7.9 0.3 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1708 PF08101.11 KFH45507.1 - 2.4e-178 593.7 0.0 3.4e-178 593.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF2560 PF10834.8 KFH45510.1 - 0.14 12.4 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Zip PF02535.22 KFH45511.1 - 8 5.6 11.3 26 3.9 11.3 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter PA26 PF04636.13 KFH45511.1 - 8.8 5.1 8.6 12 4.7 8.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mpv17_PMP22 PF04117.12 KFH45512.1 - 5.8e-25 87.3 3.0 1.1e-24 86.4 3.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Acetyltransf_1 PF00583.25 KFH45513.1 - 1e-10 41.9 0.1 1.3e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH45513.1 - 1.2e-08 34.9 0.1 1.8e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH45513.1 - 7.7e-08 32.6 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH45513.1 - 0.0016 18.4 0.2 0.0037 17.2 0.2 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFH45513.1 - 0.0016 18.5 0.1 0.0031 17.6 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFH45513.1 - 0.012 15.7 0.2 0.023 14.8 0.1 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SRP54 PF00448.22 KFH45513.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Acetyltransf_5 PF13444.6 KFH45513.1 - 0.052 14.3 0.0 0.091 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met2 PF12907.7 KFH45514.1 - 8.3e-17 61.0 5.4 1.5e-16 60.2 5.4 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KFH45514.1 - 4.8e-08 33.7 10.7 4.8e-08 33.7 10.7 1.9 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 KFH45514.1 - 0.01 15.4 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type HypA PF01155.19 KFH45514.1 - 0.026 14.5 0.8 0.029 14.4 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 KFH45514.1 - 0.16 11.7 2.5 0.93 9.3 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain JmjC PF02373.22 KFH45515.1 - 4.3e-19 69.0 0.0 7.8e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase WD40 PF00400.32 KFH45516.1 - 2.1e-12 47.4 1.9 0.0057 17.5 0.0 4.8 3 1 1 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45516.1 - 1.5e-07 31.6 1.9 0.0074 16.6 0.0 4.5 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 KFH45517.1 - 2e-29 101.6 1.0 2.5e-29 101.4 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KFH45517.1 - 0.021 15.1 0.2 0.033 14.4 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) SprT-like PF10263.9 KFH45518.1 - 2.6e-12 46.6 0.0 4.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Mito_fiss_reg PF05308.11 KFH45518.1 - 3 7.9 14.9 1.8 8.6 10.3 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator PAS_4 PF08448.10 KFH45519.1 - 0.0025 18.0 0.3 0.87 9.9 0.1 2.1 2 0 0 2 2 2 2 PAS fold ATP13 PF12921.7 KFH45519.1 - 0.048 13.5 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase expression DIOX_N PF14226.6 KFH45520.1 - 3.8e-30 105.1 0.1 4.1e-29 101.7 0.1 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH45520.1 - 4.5e-14 52.7 0.0 9.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 KFH45520.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.5 2 0 0 2 2 2 1 GxGYxYP putative glycoside hydrolase C-terminal domain Brucella_OMP2 PF05244.11 KFH45520.1 - 0.15 11.4 0.3 0.27 10.6 0.3 1.4 1 1 0 1 1 1 0 Brucella outer membrane protein 2 Methyltransf_28 PF02636.17 KFH45521.1 - 8.1e-39 133.8 0.0 1.3e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KFH45521.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CAP_N PF01213.19 KFH45522.1 - 0.99 8.8 6.9 0.92 8.9 5.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_16 PF10294.9 KFH45523.1 - 2.7e-17 63.1 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFH45523.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain F-box-like PF12937.7 KFH45524.1 - 1e-07 31.7 0.6 2.5e-07 30.5 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH45524.1 - 5e-07 29.4 0.5 1.1e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain NAD_binding_10 PF13460.6 KFH45525.1 - 1.3e-08 35.0 0.1 2.5e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH45525.1 - 1.4e-08 34.5 0.0 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFH45525.1 - 0.013 16.0 0.1 0.038 14.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH45525.1 - 0.048 13.9 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFH45525.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KFH45525.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Bap31 PF05529.12 KFH45526.1 - 2.3e-48 163.5 9.7 3e-48 163.1 9.7 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFH45526.1 - 1e-13 51.1 7.1 1e-13 51.1 7.1 1.6 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain CEP63 PF17045.5 KFH45526.1 - 0.0022 17.9 1.8 0.0037 17.2 1.6 1.4 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa Spc7 PF08317.11 KFH45526.1 - 0.024 13.5 3.7 0.034 13.0 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.6 KFH45526.1 - 0.051 13.2 4.6 0.081 12.6 4.6 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MscS_TM PF12794.7 KFH45526.1 - 0.054 12.4 3.8 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DivIC PF04977.15 KFH45526.1 - 0.061 13.1 3.0 0.17 11.7 0.5 2.8 4 0 0 4 4 4 0 Septum formation initiator V_ATPase_I PF01496.19 KFH45526.1 - 0.066 11.1 0.8 0.1 10.5 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 KFH45526.1 - 0.084 13.2 2.9 0.24 11.8 2.9 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Csm1_N PF18504.1 KFH45526.1 - 0.091 13.1 4.8 0.36 11.2 4.3 2.0 1 1 1 2 2 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 KFH45526.1 - 0.1 13.0 1.0 0.14 12.5 0.2 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KFH45526.1 - 0.34 10.9 7.4 0.4 10.7 6.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KFH45526.1 - 0.55 10.3 5.7 0.047 13.8 0.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pro_isomerase PF00160.21 KFH45530.1 - 6.7e-50 169.4 0.1 8.2e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KFH45530.1 - 0.032 14.3 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain SH3_10 PF17902.1 KFH45531.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 SH3 domain TEA PF01285.18 KFH45532.1 - 1.5e-26 92.2 0.0 3.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain DUF3504 PF12012.8 KFH45532.1 - 0.16 11.8 2.7 0.9 9.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) NmrA PF05368.13 KFH45533.1 - 1e-17 64.5 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KFH45533.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFH45533.1 - 0.0048 17.0 0.0 0.56 10.3 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KFH45533.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus GspL_C PF12693.7 KFH45534.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 GspL periplasmic domain DAP10 PF07213.11 KFH45534.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein TraL PF07178.11 KFH45534.1 - 0.2 12.1 0.1 0.4 11.2 0.1 1.4 1 0 0 1 1 1 0 TraL protein RdRP PF05183.12 KFH45535.1 - 9.2e-89 298.7 0.0 3e-77 260.6 0.0 2.5 2 1 1 3 3 3 2 RNA dependent RNA polymerase Pyr_redox_2 PF07992.14 KFH45536.1 - 1.1e-16 60.9 0.1 1.8e-16 60.3 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH45536.1 - 2.9e-07 30.0 0.0 0.0028 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH45536.1 - 1.1e-05 24.7 1.5 0.00076 18.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 KFH45536.1 - 0.00029 20.2 0.2 0.001 18.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFH45536.1 - 0.001 19.3 0.1 0.0024 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFH45536.1 - 0.001 17.9 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KFH45536.1 - 0.0018 17.4 1.3 0.0043 16.2 0.4 1.8 1 1 1 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KFH45536.1 - 0.0021 17.7 3.8 0.006 16.2 2.7 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH45536.1 - 0.021 14.1 0.2 0.083 12.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 KFH45536.1 - 0.058 12.5 0.0 2 7.5 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KFH45536.1 - 0.76 8.8 3.4 1.4 8.0 0.5 2.6 2 2 1 3 3 3 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 KFH45537.1 - 1.5e-59 201.4 0.4 1.8e-59 201.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH45537.1 - 6.5e-43 146.5 0.1 8e-43 146.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45537.1 - 2.7e-08 34.0 1.1 4.1e-08 33.3 1.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH45537.1 - 0.00085 19.2 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KFH45537.1 - 0.0033 18.1 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RecC_C PF17946.1 KFH45537.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain Polysacc_synt_2 PF02719.15 KFH45537.1 - 0.036 13.2 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ChuX_HutX PF06228.13 KFH45537.1 - 0.038 13.8 0.1 3.2 7.5 0.0 2.3 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX F_bP_aldolase PF01116.20 KFH45537.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II THF_DHG_CYH_C PF02882.19 KFH45537.1 - 0.097 12.0 0.2 0.24 10.7 0.0 1.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_12 PF08242.12 KFH45537.1 - 0.11 13.2 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45537.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_10 PF00331.20 KFH45538.1 - 1.2e-88 297.3 0.0 1.3e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CWC25 PF12542.8 KFH45539.1 - 6.8e-27 94.4 0.1 6.8e-27 94.4 0.1 3.6 3 3 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFH45539.1 - 1.6e-12 47.4 4.6 1.6e-12 47.4 4.6 4.5 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_25 PF13649.6 KFH45540.1 - 2.1e-11 44.4 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH45540.1 - 3e-11 43.4 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH45540.1 - 1.2e-09 38.7 0.0 2.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45540.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH45540.1 - 4e-06 27.5 0.0 9.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH45540.1 - 0.00037 20.1 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFH45540.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KFH45540.1 - 0.062 12.6 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFH45540.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FYDLN_acid PF09538.10 KFH45540.1 - 2 9.1 11.4 20 5.9 10.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) MutS_IV PF05190.18 KFH45542.1 - 0.078 13.3 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 MutS family domain IV Neisseria_TspB PF05616.13 KFH45542.1 - 0.5 8.8 2.9 0.64 8.4 2.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.11 KFH45542.1 - 4.3 7.3 16.6 3.3 7.7 14.5 1.9 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Abhydro_lipase PF04083.16 KFH45543.1 - 4.6e-18 64.6 0.0 9.5e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFH45543.1 - 1.3e-06 28.2 0.0 3.1e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH45543.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4687 PF15747.5 KFH45543.1 - 0.27 11.7 1.9 0.4 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) TauD PF02668.16 KFH45544.1 - 1.2e-32 113.8 0.2 1.8e-32 113.3 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Citrate_synt PF00285.21 KFH45545.1 - 1.5e-100 336.8 0.0 1.9e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain APG17 PF04108.12 KFH45546.1 - 3.2e-126 421.7 1.1 3.7e-126 421.5 1.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Bacillus_HBL PF05791.11 KFH45546.1 - 0.038 13.8 0.7 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AMP-binding PF00501.28 KFH45547.1 - 1.4e-77 261.1 0.0 2.3e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KFH45547.1 - 6e-61 205.8 0.0 1.2e-60 204.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFH45547.1 - 2.2e-51 174.1 0.5 1e-50 172.0 0.8 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45547.1 - 3.5e-40 138.0 0.8 8.2e-40 136.8 0.8 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH45547.1 - 7.4e-21 74.9 2.6 1.1e-16 61.3 0.6 2.8 3 0 0 3 3 3 2 KR domain Epimerase PF01370.21 KFH45547.1 - 1.3e-18 67.4 0.0 6.8e-12 45.4 0.0 3.1 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFH45547.1 - 1.5e-12 47.6 0.0 3.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KFH45547.1 - 3.9e-09 36.0 0.3 1.9e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFH45547.1 - 4.1e-08 32.6 0.0 0.0028 16.7 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFH45547.1 - 3.6e-06 26.3 0.3 0.083 12.0 0.0 2.8 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFH45547.1 - 6.5e-06 26.2 0.5 0.00014 21.8 0.3 2.9 3 0 0 3 3 3 1 NAD(P)H-binding AMP-binding_C PF13193.6 KFH45547.1 - 1.7e-05 25.7 1.5 3.9e-05 24.5 0.3 2.4 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KFH45547.1 - 0.0021 17.5 0.0 3.7 6.9 0.0 3.1 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KFH45547.1 - 0.13 11.6 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Alpha-amylase PF00128.24 KFH45548.1 - 2e-112 376.1 0.0 3.1e-112 375.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFH45548.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Ank_2 PF12796.7 KFH45549.1 - 1.3e-23 83.4 0.0 1.6e-05 25.4 0.0 8.7 4 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.30 KFH45549.1 - 8.1e-17 60.8 1.4 0.06 13.8 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 KFH45549.1 - 1.1e-16 59.3 8.0 0.18 12.5 0.0 11.9 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 KFH45549.1 - 4.8e-15 55.4 8.2 5.9e-05 23.3 0.1 9.1 10 0 0 10 10 10 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFH45549.1 - 1.1e-14 54.6 4.2 0.72 10.5 0.0 10.0 9 2 2 11 11 11 4 Ankyrin repeats (many copies) STAS_2 PF13466.6 KFH45549.1 - 0.014 15.7 0.1 0.049 14.0 0.1 2.0 1 0 0 1 1 1 0 STAS domain APH PF01636.23 KFH45550.1 - 0.0016 18.4 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFH45550.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 KFH45551.1 - 6.4e-09 35.7 0.2 7.6e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFH45551.1 - 7.1e-09 35.9 0.0 9.5e-09 35.5 0.0 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFH45551.1 - 0.023 13.6 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) COE1_DBD PF16422.5 KFH45553.1 - 0.051 13.0 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain NicO PF03824.16 KFH45554.1 - 2.9e-66 223.7 2.1 5.6e-66 222.8 2.1 1.4 1 0 0 1 1 1 1 High-affinity nickel-transport protein Herpes_gE PF02480.16 KFH45554.1 - 0.0024 16.7 0.0 0.048 12.4 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E MFS_Mycoplasma PF07672.13 KFH45554.1 - 0.0096 15.2 0.0 0.46 9.7 2.5 2.1 2 0 0 2 2 2 1 Mycoplasma MFS transporter DUF1230 PF06799.11 KFH45554.1 - 0.23 11.6 0.8 5.1 7.2 0.3 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF3632 PF12311.8 KFH45555.1 - 8.8e-12 45.8 0.0 2.3e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) 4HBT PF03061.22 KFH45557.1 - 1.4e-10 41.4 1.4 2.3e-10 40.7 1.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.16 KFH45558.1 - 5e-33 114.5 18.0 5e-33 114.5 18.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45558.1 - 6.5e-07 28.6 6.6 6.5e-07 28.6 6.6 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KFH45558.1 - 0.0023 16.4 4.3 0.0023 16.4 4.3 2.1 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_1_like PF12832.7 KFH45558.1 - 0.26 10.1 12.6 0.17 10.7 4.2 2.4 1 1 1 2 2 2 0 MFS_1 like family Mito_carr PF00153.27 KFH45559.1 - 1.3e-44 150.0 3.6 3.5e-20 71.7 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KFH45563.1 - 7.1e-37 127.1 27.8 7.1e-37 127.1 27.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PALP PF00291.25 KFH45565.1 - 4.1e-35 121.6 0.1 5e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EGF_3 PF12947.7 KFH45566.1 - 9.1e-05 22.6 38.4 1.5 9.1 0.9 7.0 4 3 0 4 4 4 4 EGF domain Galanin PF01296.18 KFH45566.1 - 0.0014 18.6 7.2 13 5.9 0.0 5.5 6 0 0 6 6 6 3 Galanin Fungal_trans PF04082.18 KFH45567.1 - 1.4e-14 53.8 0.3 2.4e-14 53.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45567.1 - 3e-08 33.6 13.0 7.3e-08 32.4 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 KFH45569.1 - 3.6e-66 223.8 0.3 4.3e-66 223.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH45569.1 - 9.9e-09 35.7 1.8 2.7e-07 31.0 0.5 2.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFH45569.1 - 0.006 16.4 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Glyco_hydro_92 PF07971.12 KFH45570.1 - 1.5e-131 439.5 2.2 1.9e-131 439.2 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFH45570.1 - 1.4e-45 156.1 1.9 2.2e-45 155.4 1.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain SpoIIE PF07228.12 KFH45571.1 - 1.2e-11 44.9 0.2 4e-11 43.2 0.2 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFH45571.1 - 3.9e-10 39.7 0.4 5.9e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFH45571.1 - 0.002 17.8 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Ribosomal_S14 PF00253.21 KFH45573.1 - 3.9e-22 77.8 0.7 3.9e-22 77.8 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Arylsulfotran_2 PF14269.6 KFH45574.1 - 3.9e-61 207.0 0.5 5.3e-61 206.6 0.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFH45574.1 - 2.5e-19 69.4 0.1 6.2e-19 68.1 0.1 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Choline_transpo PF04515.12 KFH45575.1 - 8.7e-84 281.5 18.2 8.7e-84 281.5 18.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Ferlin_C PF16165.5 KFH45575.1 - 0.5 10.3 4.1 1.2 9.0 4.1 1.6 1 0 0 1 1 1 0 Ferlin C-terminus ICL PF00463.21 KFH45576.1 - 1.5e-198 660.6 0.0 1.8e-198 660.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFH45576.1 - 1.4e-11 44.3 0.1 3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase Gln-synt_C PF00120.24 KFH45577.1 - 4.2e-83 279.2 0.0 5.1e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain E1-E2_ATPase PF00122.20 KFH45578.1 - 1.2e-34 119.4 26.1 3.8e-31 108.0 2.0 3.9 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH45578.1 - 1.4e-25 90.0 0.9 1.4e-25 90.0 0.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFH45578.1 - 1.1e-19 71.5 1.3 1.6e-15 58.0 0.1 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH45578.1 - 8.3e-16 57.4 0.0 1.9e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFH45578.1 - 1.1e-13 51.0 0.0 2.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFH45578.1 - 1.1e-05 25.3 0.3 0.00017 21.4 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p6 PF17548.2 KFH45578.1 - 0.11 12.4 0.4 0.29 11.1 0.4 1.6 1 0 0 1 1 1 0 Histone-like Protein p6 Ras PF00071.22 KFH45580.1 - 6.7e-53 178.6 0.0 7.8e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH45580.1 - 9.1e-22 77.5 0.0 1.7e-21 76.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH45580.1 - 7e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFH45580.1 - 0.00028 20.3 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFH45580.1 - 0.0016 17.7 0.0 0.011 14.9 0.0 1.7 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 KFH45580.1 - 0.0054 16.2 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFH45580.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_16 PF00722.21 KFH45581.1 - 6.8e-40 136.4 1.0 1.1e-39 135.7 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NAGPA PF09992.9 KFH45582.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphodiester glycosidase Glyco_hydro_62 PF03664.13 KFH45583.1 - 6.3e-139 461.9 4.7 7.2e-139 461.7 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Cadherin_3 PF16184.5 KFH45583.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Cadherin-like Zn_clus PF00172.18 KFH45584.1 - 1.9e-09 37.5 9.8 3.9e-09 36.5 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH45584.1 - 3.1e-05 23.0 0.3 6.2e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AA_permease PF00324.21 KFH45585.1 - 1.7e-135 452.3 45.4 2e-135 452.1 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH45585.1 - 2.3e-34 118.9 50.2 3e-34 118.6 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 KFH45585.1 - 9.9 6.3 9.8 0.41 10.7 0.7 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Sugar_tr PF00083.24 KFH45586.1 - 4.9e-91 305.8 15.9 6.1e-91 305.5 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45586.1 - 3.5e-22 78.8 19.0 4.1e-14 52.3 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH45586.1 - 2.1e-06 26.6 15.8 0.0017 17.0 0.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KFH45586.1 - 0.0015 17.9 0.9 0.0015 17.9 0.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KFH45586.1 - 0.34 9.7 13.2 0.016 14.1 4.1 2.2 2 0 0 2 2 2 0 MFS_1 like family Peptidase_C65 PF10275.9 KFH45587.1 - 4e-54 183.7 0.0 2.4e-53 181.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase C65 Otubain Colicin_Pyocin PF01320.18 KFH45587.1 - 0.19 11.8 0.1 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein Peptidase_C2 PF00648.21 KFH45588.1 - 1.6e-57 194.8 0.1 1.6e-57 194.8 0.1 2.6 2 1 0 2 2 2 1 Calpain family cysteine protease Ldh_2 PF02615.14 KFH45589.1 - 1.2e-123 412.6 1.8 1.3e-123 412.4 1.8 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase SLR1-BP PF07333.12 KFH45590.1 - 0.0026 18.2 3.9 0.0039 17.6 3.9 1.2 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Defensin_2 PF01097.18 KFH45590.1 - 0.016 15.2 6.9 0.024 14.6 6.9 1.3 1 0 0 1 1 1 0 Arthropod defensin Toxin_31 PF08119.11 KFH45590.1 - 0.31 10.8 4.8 0.52 10.1 4.8 1.3 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family Zn_clus PF00172.18 KFH45591.1 - 2.8e-09 37.0 8.0 4.8e-09 36.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH45591.1 - 0.0022 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PCI PF01399.27 KFH45592.1 - 1.6e-18 67.2 0.1 5.2e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain XLF PF09302.11 KFH45592.1 - 0.085 13.0 0.5 0.37 11.0 0.1 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Pkinase PF00069.25 KFH45593.1 - 9.2e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFH45593.1 - 0.0099 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFH45593.1 - 0.012 14.9 0.0 0.19 11.0 0.0 2.2 1 1 0 1 1 1 0 Protein tyrosine kinase Mito_carr PF00153.27 KFH45597.1 - 1.6e-41 140.1 0.6 1.1e-18 66.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KFH45598.1 - 9.9e-19 67.5 35.0 2.3e-18 66.3 35.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KFH45599.1 - 4.4e-91 305.5 1.0 5e-91 305.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KFH45599.1 - 0.0065 16.0 5.4 0.11 12.0 1.8 2.9 1 1 2 3 3 3 2 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 KFH45599.1 - 0.038 12.5 0.2 0.065 11.7 0.2 1.4 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 MiaE PF06175.11 KFH45599.1 - 0.15 11.6 0.1 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) CoA_trans PF01144.23 KFH45600.1 - 4.9e-91 303.9 1.3 1.1e-52 178.6 0.0 2.3 2 1 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFH45600.1 - 0.0051 16.8 0.5 0.011 15.7 0.1 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KFH45600.1 - 0.12 10.6 0.7 0.24 9.7 0.1 1.6 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter RIO1 PF01163.22 KFH45602.1 - 5.5e-67 225.0 0.2 1.2e-66 223.9 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFH45602.1 - 0.0078 16.2 0.1 1.7 8.5 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family YL1 PF05764.13 KFH45602.1 - 0.63 10.1 27.7 1 9.4 15.3 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF1115 PF06544.12 KFH45603.1 - 2.9e-14 53.4 0.0 4.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) MFS_1 PF07690.16 KFH45604.1 - 1.1e-22 80.4 53.4 2.3e-14 53.1 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rieske PF00355.26 KFH45605.1 - 3.3e-08 33.3 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFH45605.1 - 6.7e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Cnd1_N PF12922.7 KFH45606.1 - 5.9e-62 208.4 0.0 8e-61 204.7 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KFH45606.1 - 8.4e-43 146.2 5.2 3.9e-39 134.3 0.0 4.1 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFH45606.1 - 4e-10 39.0 4.7 0.023 14.9 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFH45606.1 - 7.7e-09 35.8 3.3 0.00026 21.3 0.2 4.4 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KFH45606.1 - 1.9e-05 25.0 4.5 0.12 12.9 0.1 5.0 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 KFH45606.1 - 9.9e-05 21.1 5.0 0.041 12.4 0.0 3.3 3 2 0 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 KFH45606.1 - 0.00091 19.4 0.0 0.62 10.3 0.0 3.4 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KFH45606.1 - 0.0039 16.4 3.7 0.0071 15.6 0.3 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain AAA_27 PF13514.6 KFH45606.1 - 0.067 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain GRIM-19 PF06212.12 KFH45607.1 - 1.7e-24 86.3 0.2 3.3e-24 85.3 0.2 1.4 1 1 0 1 1 1 1 GRIM-19 protein Ribosomal_L27A PF00828.19 KFH45608.1 - 2.4e-20 73.5 0.0 3.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NmrA PF05368.13 KFH45610.1 - 6.7e-17 61.8 0.0 9.2e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH45610.1 - 1.5e-13 51.0 0.0 6.4e-13 49.0 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFH45610.1 - 0.032 13.7 0.0 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HTH_ParB PF17762.1 KFH45610.1 - 0.074 12.9 0.1 15 5.5 0.1 2.4 2 0 0 2 2 2 0 HTH domain found in ParB protein Semialdhyde_dh PF01118.24 KFH45610.1 - 0.13 12.7 0.0 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KFH45611.1 - 1.1e-46 159.6 0.0 8.6e-46 156.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFH45611.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF2167 PF09935.9 KFH45614.1 - 0.056 12.6 0.6 0.25 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) MatE PF01554.18 KFH45615.1 - 1.2e-09 38.0 7.1 1.2e-09 38.0 7.1 3.0 3 0 0 3 3 3 2 MatE DUF3040 PF11239.8 KFH45615.1 - 3 8.2 11.1 30 5.0 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Chorismate_bind PF00425.18 KFH45617.1 - 3.8e-70 236.4 0.0 1.5e-69 234.4 0.0 2.0 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KFH45617.1 - 4.2e-27 95.2 0.0 7.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KFH45617.1 - 9.8e-17 61.5 0.0 2.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KFH45617.1 - 0.0015 18.3 0.1 0.3 10.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase C26 HMGL-like PF00682.19 KFH45618.1 - 4e-59 200.3 0.9 1.7e-58 198.2 0.9 2.0 1 1 0 1 1 1 1 HMGL-like Peptidase_M14 PF00246.24 KFH45619.1 - 8.8e-37 127.5 0.0 1.3e-36 126.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NUDIX PF00293.28 KFH45620.1 - 3.8e-09 36.7 0.0 6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.21 KFH45621.1 - 1e-39 136.5 0.0 5.7e-39 134.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 KFH45622.1 - 4.2e-52 174.0 3.6 2.5e-22 78.6 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PP-binding PF00550.25 KFH45623.1 - 5.1e-11 42.8 0.1 7e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFH45623.1 - 0.00029 21.0 0.3 0.00049 20.3 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier DUF4703 PF15775.5 KFH45624.1 - 0.22 11.3 1.6 0.32 10.8 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4703) Peptidase_M28 PF04389.17 KFH45625.1 - 1.7e-40 138.8 0.0 2.6e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFH45625.1 - 2.1e-14 53.3 0.3 5.3e-14 52.0 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFH45625.1 - 1.2e-06 28.3 0.1 2.3e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3645 PF12359.8 KFH45625.1 - 0.17 11.3 0.1 0.4 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Fungal_trans PF04082.18 KFH45626.1 - 1.5e-13 50.4 0.0 2.5e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45626.1 - 1.3e-05 25.2 9.2 3.1e-05 24.0 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFH45626.1 - 0.0017 18.7 18.0 0.0018 18.6 4.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH45626.1 - 0.0064 17.2 2.7 0.0064 17.2 2.7 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH45626.1 - 0.014 15.7 0.1 0.014 15.7 0.1 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KFH45626.1 - 0.33 10.9 7.7 0.92 9.5 7.7 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KFH45626.1 - 0.63 10.6 14.9 0.27 11.7 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain DUF2370 PF10176.9 KFH45629.1 - 1.2e-88 296.6 0.0 3e-88 295.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM252 PF15664.5 KFH45629.1 - 0.068 12.9 0.6 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 252 family PQQ_3 PF13570.6 KFH45629.1 - 0.73 10.4 6.2 3 8.4 1.8 2.8 2 0 0 2 2 2 0 PQQ-like domain TFIIF_alpha PF05793.12 KFH45629.1 - 0.85 8.1 3.7 1.2 7.6 3.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KFH45629.1 - 4.3 7.8 7.6 0.89 10.0 2.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Beta-lactamase PF00144.24 KFH45631.1 - 5.7e-40 137.6 0.1 8.4e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Aldedh PF00171.22 KFH45633.1 - 4.4e-136 454.0 1.4 5.5e-136 453.7 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RraA-like PF03737.15 KFH45633.1 - 0.055 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Aldolase/RraA SNF2_N PF00176.23 KFH45634.1 - 6.2e-47 160.0 0.1 9.7e-47 159.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFH45634.1 - 1.6e-10 41.3 0.0 9.9e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH45634.1 - 2.5e-06 27.4 0.0 1.4e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2252 PF10009.9 KFH45634.1 - 0.15 11.1 1.5 7.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) BAF1_ABF1 PF04684.13 KFH45635.1 - 0.024 13.7 0.7 0.027 13.6 0.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.19 KFH45635.1 - 0.51 11.0 8.0 1.6 9.4 8.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.6 KFH45638.1 - 6.7e-60 202.1 0.0 1.4e-59 201.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFH45638.1 - 7.9e-42 142.8 0.0 1.3e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.6 KFH45638.1 - 0.0038 17.5 0.3 0.46 10.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFH45638.1 - 0.0039 17.2 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH45638.1 - 0.044 13.5 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KFH45638.1 - 0.057 13.0 0.1 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain bZIP_2 PF07716.15 KFH45641.1 - 1.3e-06 28.4 11.7 2.6e-06 27.4 11.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFH45641.1 - 9.8e-06 25.6 6.5 1.7e-05 24.8 6.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor FAM199X PF15814.5 KFH45641.1 - 0.016 14.3 5.3 0.029 13.4 5.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X TPD52 PF04201.15 KFH45641.1 - 0.054 13.1 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Macoilin PF09726.9 KFH45641.1 - 0.24 9.9 3.1 0.31 9.6 3.1 1.2 1 0 0 1 1 1 0 Macoilin family Takusan PF04822.13 KFH45641.1 - 0.43 10.5 4.6 0.24 11.3 1.4 2.2 2 0 0 2 2 2 0 Takusan Apt1 PF10351.9 KFH45641.1 - 0.55 9.0 5.3 0.77 8.6 5.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mucin PF01456.17 KFH45641.1 - 0.7 9.9 19.6 1.2 9.2 19.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein NAM-associated PF14303.6 KFH45641.1 - 6 7.6 9.8 1.8 9.2 6.6 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 KFH45641.1 - 6.5 7.4 13.4 0.11 13.1 5.5 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Beach PF02138.18 KFH45642.1 - 6.8e-118 393.0 0.0 1.1e-117 392.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFH45642.1 - 2.4e-11 43.6 0.1 5.5e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KFH45642.1 - 3.8e-10 40.1 0.1 8e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 KFH45642.1 - 0.00032 20.1 2.8 0.00088 18.6 2.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 KFH45642.1 - 0.015 16.1 4.8 9.7 7.3 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Ubiquitin_2 PF14560.6 KFH45643.1 - 0.00029 21.2 0.0 3 8.4 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-like domain NRho PF16733.5 KFH45643.1 - 0.0098 15.9 0.2 11 6.1 0.0 3.4 3 0 0 3 3 3 1 Rhomboid N-terminal domain Mce4_CUP1 PF11887.8 KFH45643.1 - 0.059 12.8 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 KFH45643.1 - 0.076 13.5 3.0 52 4.4 0.0 4.3 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Clp_N PF02861.20 KFH45643.1 - 8.1 6.7 12.5 14 5.9 0.1 5.7 5 1 1 6 6 6 0 Clp amino terminal domain, pathogenicity island component NIF PF03031.18 KFH45644.1 - 2.3e-28 98.9 0.3 8.2e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KFH45644.1 - 3e-08 33.9 0.0 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFH45644.1 - 6.1e-05 22.9 0.0 0.00016 21.6 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFH45644.1 - 0.00016 22.0 0.0 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFH45644.1 - 0.00039 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFH45644.1 - 0.014 15.7 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Biotin_lipoyl PF00364.22 KFH45644.1 - 0.1 12.5 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme DDOST_48kD PF03345.14 KFH45645.1 - 8.8e-161 535.4 0.0 1e-160 535.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 KFH45645.1 - 0.0074 14.7 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) adh_short PF00106.25 KFH45646.1 - 6.7e-20 71.4 0.0 7.6e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45646.1 - 1.1e-09 38.2 0.0 6.9e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH45646.1 - 4.5e-06 26.7 0.0 8.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH45646.1 - 0.00024 20.7 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFH45646.1 - 0.0028 17.7 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFH45646.1 - 0.0036 17.5 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KFH45646.1 - 0.0049 16.1 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFH45646.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFH45646.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFH45646.1 - 0.097 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 KFH45647.1 - 1.5e-40 139.2 0.0 1.3e-39 136.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45647.1 - 1e-12 47.9 0.0 6.5e-08 32.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KFH45647.1 - 0.0025 17.8 0.1 0.024 14.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH45647.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase CDC45 PF02724.14 KFH45647.1 - 3.6 5.8 5.7 4.7 5.4 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP PF00230.20 KFH45649.1 - 5.9e-47 160.3 12.5 7.3e-47 160.0 12.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-rbx1 PF12678.7 KFH45652.1 - 3e-07 30.6 2.7 3e-07 30.6 2.7 2.5 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFH45652.1 - 1.8e-05 25.0 6.2 1.8e-05 25.0 6.2 3.4 2 2 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH45652.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 2.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFH45652.1 - 0.00031 20.8 1.3 0.00031 20.8 1.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KFH45652.1 - 0.00049 19.9 0.3 0.00049 19.9 0.3 3.4 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH45652.1 - 0.0051 16.7 2.8 0.0051 16.7 2.8 3.0 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH45652.1 - 0.0082 16.0 1.6 0.0082 16.0 1.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFH45652.1 - 0.019 15.1 0.8 0.019 15.1 0.8 3.2 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KFH45653.1 - 0.012 14.9 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Fer4 PF00037.27 KFH45654.1 - 4.2e-14 51.7 16.4 5.8e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFH45654.1 - 5.3e-13 49.3 10.7 8.7e-13 48.6 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFH45654.1 - 6.5e-11 43.0 7.0 7.4e-05 23.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KFH45654.1 - 3.5e-10 39.9 4.7 7.4e-05 22.8 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFH45654.1 - 4.6e-09 36.2 21.3 8.9e-07 28.9 12.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFH45654.1 - 1.9e-08 34.3 10.1 4.1e-08 33.3 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFH45654.1 - 3.8e-07 30.4 19.7 0.00011 22.5 11.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFH45654.1 - 7.4e-07 29.0 16.9 0.0002 21.3 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KFH45654.1 - 9.7e-07 28.5 12.2 0.0028 17.7 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KFH45654.1 - 2e-05 24.7 11.6 0.00066 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KFH45654.1 - 8.6e-05 23.0 11.7 0.017 15.7 12.8 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFH45654.1 - 0.031 14.5 9.3 0.5 10.6 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KFH45654.1 - 0.042 14.0 4.9 0.23 11.6 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S c-SKI_SMAD_bind PF08782.10 KFH45654.1 - 0.051 13.8 9.2 0.74 10.1 0.5 2.6 2 1 1 3 3 3 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KFH45654.1 - 0.075 13.6 14.8 0.81 10.3 4.0 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KFH45654.1 - 0.086 13.8 16.6 0.4 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 KFH45654.1 - 0.4 10.7 5.8 0.17 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 KFH45654.1 - 0.45 11.4 12.1 3.7 8.5 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NUDIX PF00293.28 KFH45655.1 - 2e-16 60.2 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.22 KFH45656.1 - 1.3e-77 261.6 0.0 1.6e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KFH45657.1 - 5.8e-10 39.6 5.5 0.034 15.0 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat DpnD-PcfM PF14207.6 KFH45657.1 - 0.012 15.5 1.3 0.03 14.2 1.3 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein zf-CCCH PF00642.24 KFH45661.1 - 7.7e-11 41.6 8.1 3.2e-05 23.7 2.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFH45661.1 - 2.4e-10 40.0 10.6 1.5e-05 24.7 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFH45661.1 - 4.6e-10 39.2 17.4 7.6e-05 22.6 4.2 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KFH45661.1 - 6.6e-09 36.4 6.4 6.2e-05 23.7 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KFH45661.1 - 9.1e-06 25.9 1.6 1.9e-05 24.8 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFH45661.1 - 0.039 14.4 18.2 0.76 10.3 6.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Isy1 PF06246.12 KFH45662.1 - 7.9e-91 304.1 3.2 9e-91 304.0 3.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PCMT PF01135.19 KFH45663.1 - 4.9e-55 186.5 0.0 6e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFH45663.1 - 4.2e-06 26.6 0.0 1e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFH45663.1 - 9.8e-06 25.6 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH45663.1 - 3.7e-05 24.4 0.0 6.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH45663.1 - 0.00057 20.5 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH45663.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH45663.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 KFH45663.1 - 0.095 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 KFH45663.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KFH45663.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) COesterase PF00135.28 KFH45664.1 - 1.9e-85 287.7 0.0 2.6e-85 287.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH45664.1 - 1e-07 32.1 0.0 3.5e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH45664.1 - 2.4e-06 27.2 0.3 4.1e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFH45664.1 - 4.7 7.8 7.1 1.4 9.5 1.8 2.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.14 KFH45665.1 - 2.4e-66 223.6 0.2 2.8e-66 223.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_3 PF00202.21 KFH45666.1 - 9.6e-38 129.9 0.0 7.2e-20 71.0 0.0 3.8 4 1 0 4 4 4 2 Aminotransferase class-III AAA_26 PF13500.6 KFH45666.1 - 1.6e-15 57.5 0.0 2.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain PALP PF00291.25 KFH45667.1 - 1.7e-48 165.6 1.1 2.1e-48 165.3 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Plasmodium_Vir PF05795.11 KFH45668.1 - 0.25 10.7 0.9 0.29 10.5 0.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 KFH45668.1 - 7.8 4.7 6.2 9.4 4.5 6.2 1.0 1 0 0 1 1 1 0 Menin Aminotran_1_2 PF00155.21 KFH45670.1 - 3.7e-37 128.4 0.0 4.2e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KFH45670.1 - 0.16 10.7 0.0 0.34 9.6 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KFH45670.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Helicase_C PF00271.31 KFH45671.1 - 2.3e-09 37.6 0.0 4.2e-09 36.7 0.0 1.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cutinase PF01083.22 KFH45672.1 - 7.1e-43 146.6 0.2 8.9e-43 146.3 0.2 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.20 KFH45672.1 - 3.4e-05 24.1 0.0 5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 KFH45672.1 - 0.00061 19.4 0.1 0.00094 18.8 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KFH45672.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KFH45672.1 - 0.024 14.2 0.2 0.035 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KFH45672.1 - 0.029 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KFH45672.1 - 0.095 12.2 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family VirJ PF06057.11 KFH45672.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF676 PF05057.14 KFH45672.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFH45672.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KFH45672.1 - 0.16 12.6 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADH_N PF08240.12 KFH45674.1 - 2.1e-21 75.8 0.4 3.8e-21 75.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH45674.1 - 1.7e-19 70.1 0.4 3.1e-19 69.3 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH45674.1 - 1.4e-06 27.9 0.2 2.5e-06 27.2 0.2 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFH45674.1 - 0.001 18.4 0.5 0.0018 17.6 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Redoxin PF08534.10 KFH45674.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin ADH_N_2 PF16884.5 KFH45674.1 - 0.16 11.9 0.0 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase Menin PF05053.13 KFH45675.1 - 7.1 4.9 6.3 8.1 4.7 6.3 1.1 1 0 0 1 1 1 0 Menin CN_hydrolase PF00795.22 KFH45676.1 - 3.2e-27 95.5 0.0 5.9e-27 94.6 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PAF-AH_p_II PF03403.13 KFH45677.1 - 3.6e-34 117.9 0.0 1.9e-30 105.6 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFH45677.1 - 1.6e-05 23.9 0.0 0.00012 21.1 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFH45677.1 - 0.0012 18.1 0.1 0.082 12.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFH45677.1 - 0.0015 17.7 0.0 0.004 16.2 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase adh_short_C2 PF13561.6 KFH45678.1 - 3.3e-56 190.4 1.4 3.9e-56 190.2 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH45678.1 - 6.2e-44 149.8 1.0 7.7e-44 149.5 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH45678.1 - 1.5e-07 31.5 0.2 2.1e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH45678.1 - 0.033 14.1 0.2 0.05 13.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 KFH45678.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Transp_cyt_pur PF02133.15 KFH45679.1 - 4.6e-32 111.3 32.7 4.8e-30 104.7 32.7 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S8 PF00082.22 KFH45680.1 - 1.5e-32 113.0 6.6 3e-32 112.1 6.6 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH45680.1 - 1.7e-18 67.1 0.1 4.6e-18 65.7 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 PurL_C PF16904.5 KFH45680.1 - 0.024 14.9 0.3 0.055 13.8 0.3 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus GRAM PF02893.20 KFH45681.1 - 4.9e-34 116.6 0.8 1e-20 73.7 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KFH45681.1 - 2.1e-28 99.1 0.0 4e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KFH45681.1 - 1.1e-12 48.3 0.0 3.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFH45681.1 - 6.3e-06 26.4 0.1 0.00017 21.8 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KFH45681.1 - 4.9e-05 22.3 0.0 8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KFH45681.1 - 0.0017 18.7 0.5 0.014 15.8 0.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFH45681.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 PH domain AMP-binding PF00501.28 KFH45682.1 - 6.5e-73 245.7 0.1 9.7e-73 245.2 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH45682.1 - 0.0013 19.7 0.0 0.0033 18.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.16 KFH45682.1 - 0.28 11.3 3.7 2.7 8.1 0.4 2.6 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF3995 PF13160.6 KFH45682.1 - 2 8.8 9.9 0.065 13.6 2.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) ABC_membrane PF00664.23 KFH45683.1 - 3e-82 276.4 29.9 4.4e-45 154.5 13.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH45683.1 - 2.8e-69 231.9 0.0 3.4e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH45683.1 - 4.5e-14 52.4 2.6 1.9e-05 24.2 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KFH45683.1 - 7.5e-09 35.2 0.1 0.00024 20.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_29 PF13555.6 KFH45683.1 - 1.2e-08 34.5 0.2 0.0023 17.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH45683.1 - 2.2e-08 34.5 0.4 0.0024 18.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFH45683.1 - 1.3e-07 32.1 3.0 0.0032 17.8 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFH45683.1 - 2.4e-07 30.8 0.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KFH45683.1 - 8.8e-06 24.8 4.9 0.047 12.5 0.7 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KFH45683.1 - 4e-05 23.5 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFH45683.1 - 5.1e-05 22.9 0.1 0.3 10.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 KFH45683.1 - 0.00015 21.0 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KFH45683.1 - 0.00022 21.2 0.2 5 6.8 0.2 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFH45683.1 - 0.00029 20.6 2.8 1.3 8.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KFH45683.1 - 0.0017 18.5 0.2 12 6.2 0.1 4.4 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFH45683.1 - 0.0021 18.6 0.1 0.41 11.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFH45683.1 - 0.0027 17.9 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KFH45683.1 - 0.0033 17.3 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 KFH45683.1 - 0.0056 16.7 0.2 8.4 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFH45683.1 - 0.012 14.8 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 KFH45683.1 - 0.016 15.1 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 KFH45683.1 - 0.019 14.9 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 KFH45683.1 - 0.028 14.5 0.0 4.8 7.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 KFH45683.1 - 0.03 14.4 0.3 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KFH45683.1 - 0.036 13.6 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KFH45683.1 - 0.036 13.2 0.1 4.9 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KFH45683.1 - 0.053 13.3 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KFH45683.1 - 0.059 13.1 0.1 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH45683.1 - 0.16 12.4 0.2 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KFH45683.1 - 0.17 12.0 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase HHV-5_US34A PF17087.5 KFH45683.1 - 0.18 12.0 0.2 0.47 10.6 0.2 1.6 1 0 0 1 1 1 0 Herpesvirus US34A protein family NACHT PF05729.12 KFH45683.1 - 0.19 11.6 0.5 17 5.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 KFH45684.1 - 1.7e-14 53.9 0.0 4.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45684.1 - 8.7e-05 21.9 0.0 0.02 14.2 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase Methyltransf_23 PF13489.6 KFH45686.1 - 8.9e-12 45.2 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH45686.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH45686.1 - 6.8e-10 39.5 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH45686.1 - 4e-09 37.1 0.0 7.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH45686.1 - 3e-07 31.1 0.0 4.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH45686.1 - 7.3e-06 25.5 0.0 9.9e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KFH45686.1 - 0.0015 19.5 0.0 0.0028 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFH45686.1 - 0.0023 17.8 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 KFH45686.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KFH45686.1 - 0.019 15.1 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.25 KFH45687.1 - 2.8e-61 207.2 0.0 4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45687.1 - 1e-46 159.4 0.0 1.5e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH45687.1 - 3.7e-07 29.8 0.0 5.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFH45687.1 - 0.0023 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFH45687.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFH45687.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nucleos_tra2_C PF07662.13 KFH45688.1 - 1e-69 234.6 1.1 1e-69 234.6 1.1 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFH45688.1 - 1.3e-23 83.4 1.0 1.3e-23 83.4 1.0 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Ribosomal_S2 PF00318.20 KFH45689.1 - 9.4e-63 211.3 3.9 5.7e-62 208.7 0.1 2.9 2 1 0 2 2 2 1 Ribosomal protein S2 LDcluster4 PF18306.1 KFH45689.1 - 0.018 14.6 0.4 0.018 14.6 0.4 1.7 2 0 0 2 2 2 0 SLOG cluster4 family PA26 PF04636.13 KFH45689.1 - 0.18 10.7 1.2 0.31 9.9 1.2 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MMtag PF10159.9 KFH45689.1 - 1.1 9.5 4.1 3.9 7.8 1.5 2.6 2 0 0 2 2 2 0 Multiple myeloma tumor-associated EI24 PF07264.11 KFH45690.1 - 5.9e-05 23.4 23.4 0.00012 22.4 23.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PalH PF08733.10 KFH45690.1 - 0.11 11.4 0.6 0.18 10.8 0.6 1.2 1 0 0 1 1 1 0 PalH/RIM21 GFA PF04828.14 KFH45691.1 - 1.8e-15 57.0 1.6 2.8e-15 56.4 1.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme AtuA PF07287.11 KFH45693.1 - 2.8e-129 430.8 0.1 3.4e-129 430.6 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA LYTB PF02401.18 KFH45693.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 LytB protein zf-C2H2_jaz PF12171.8 KFH45694.1 - 4.1e-10 39.7 0.2 6.6e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH45694.1 - 0.0018 18.6 0.2 0.0034 17.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFH45694.1 - 0.027 14.8 0.1 0.035 14.4 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFH45694.1 - 0.076 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 KFH45694.1 - 0.14 13.1 0.2 0.3 12.0 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Transferase PF02458.15 KFH45695.1 - 2e-15 56.4 0.0 9.1e-10 37.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family SAPS PF04499.15 KFH45696.1 - 7.7e-190 631.8 4.4 1.4e-189 631.0 0.0 2.7 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein MFS_1 PF07690.16 KFH45697.1 - 1.8e-15 56.7 55.1 2.5e-14 53.0 42.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GCFC PF07842.12 KFH45698.1 - 3.5e-69 233.5 5.0 3.5e-69 233.5 5.0 1.4 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFH45698.1 - 8.9e-13 47.9 4.1 2e-12 46.8 4.1 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFH45698.1 - 2.2e-11 44.1 9.7 2.2e-11 44.1 9.7 2.6 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KFH45698.1 - 2.1e-08 34.1 4.3 1.1e-06 28.6 2.7 3.6 3 0 0 3 3 3 1 G-patch domain Sel1 PF08238.12 KFH45699.1 - 1.4e-16 60.6 25.9 4e-07 30.5 0.2 7.5 7 0 0 7 7 7 6 Sel1 repeat TPR_1 PF00515.28 KFH45699.1 - 0.13 12.1 0.7 0.79 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 KFH45700.1 - 2.2e-21 76.2 0.1 1e-20 74.1 0.0 2.1 3 0 0 3 3 3 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KFH45700.1 - 3.3e-11 43.1 3.6 1.6e-07 31.0 1.5 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KFH45700.1 - 0.027 14.1 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 EKLF_TAD1 PF16832.5 KFH45700.1 - 0.044 13.6 0.8 0.12 12.3 0.8 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Glyco_hydro_42 PF02449.15 KFH45700.1 - 0.07 12.5 0.4 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase DUF3429 PF11911.8 KFH45701.1 - 3.8e-39 134.2 9.8 5e-39 133.9 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Ctr PF04145.15 KFH45701.1 - 0.023 15.3 2.4 0.023 15.3 2.4 2.3 2 1 0 2 2 2 0 Ctr copper transporter family Peptidase_S49_N PF08496.10 KFH45701.1 - 0.078 13.0 7.3 0.17 12.0 7.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Herpes_gE PF02480.16 KFH45701.1 - 0.15 10.8 0.6 0.23 10.1 0.6 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E V_ATPase_I PF01496.19 KFH45701.1 - 0.25 9.2 1.1 0.36 8.7 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 KFH45701.1 - 3.2 7.8 5.8 17 5.5 4.4 2.0 2 0 0 2 2 2 0 DDHD domain Connexin PF00029.19 KFH45701.1 - 3.3 7.4 5.8 5.9 6.6 5.4 1.7 2 0 0 2 2 2 0 Connexin ketoacyl-synt PF00109.26 KFH45702.1 - 1.2e-59 202.0 0.2 4.4e-46 157.5 0.1 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH45702.1 - 7.6e-50 169.3 0.2 2.4e-49 167.7 0.2 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH45702.1 - 1.4e-46 159.1 2.4 2.6e-46 158.2 2.4 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFH45702.1 - 2.8e-35 122.4 0.0 4.1e-34 118.5 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFH45702.1 - 4.4e-33 113.8 0.0 1.5e-32 112.0 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFH45702.1 - 9e-16 58.3 0.7 1.6e-14 54.3 0.7 2.7 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KFH45702.1 - 1.8e-15 57.4 0.0 7.2e-15 55.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KFH45702.1 - 1.1e-13 52.4 0.0 4.4e-12 47.2 0.0 3.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFH45702.1 - 8.5e-12 44.9 0.3 2.2e-11 43.6 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KFH45702.1 - 1.3e-11 44.5 0.0 4.1e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH45702.1 - 2.3e-11 44.3 1.2 1.2e-10 41.9 0.0 3.1 3 0 0 3 3 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KFH45702.1 - 5e-11 42.7 0.1 5e-10 39.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KFH45702.1 - 1.1e-10 42.0 0.0 6.1e-10 39.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFH45702.1 - 5e-09 36.4 0.0 1.6e-08 34.7 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFH45702.1 - 2.1e-08 33.8 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFH45702.1 - 8.6e-08 32.2 0.0 2.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFH45702.1 - 5.1e-06 26.2 1.0 1.4e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KFH45702.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase SAT PF16073.5 KFH45702.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_28 PF02636.17 KFH45702.1 - 0.0028 17.3 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KFH45702.1 - 0.015 16.3 0.2 0.12 13.4 0.0 2.8 2 0 0 2 2 1 0 Methyltransferase domain Thiolase_N PF00108.23 KFH45702.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF938 PF06080.12 KFH45702.1 - 0.15 11.8 0.0 1.6 8.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF938) Coatomer_WDAD PF04053.14 KFH45703.1 - 3.5e-145 484.5 0.0 5.3e-145 483.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFH45703.1 - 9.5e-100 334.2 0.0 1.2e-99 333.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFH45703.1 - 2e-36 123.4 15.5 2.4e-07 31.3 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45703.1 - 4.5e-08 33.3 1.0 0.0018 18.5 0.0 5.4 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH45703.1 - 0.017 13.8 4.5 2 6.9 0.0 4.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PAS_9 PF13426.7 KFH45704.1 - 5.9e-28 97.2 0.0 1.1e-18 67.4 0.1 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KFH45704.1 - 2.6e-20 72.5 0.0 3.7e-12 46.4 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KFH45704.1 - 6.8e-18 64.7 0.8 4.3e-06 26.7 0.0 4.7 4 1 0 4 4 4 3 PAS fold GATA PF00320.27 KFH45704.1 - 5.1e-15 54.8 8.9 1e-14 53.9 8.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 KFH45704.1 - 3.4e-07 30.4 1.9 0.019 15.1 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KFH45704.1 - 1.2e-05 25.5 0.9 0.21 11.8 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_2 PF08446.11 KFH45704.1 - 0.00018 22.1 0.0 0.36 11.5 0.0 3.7 3 0 0 3 3 3 1 PAS fold Pro-rich_19 PF15455.6 KFH45704.1 - 0.0016 17.7 0.4 0.0016 17.7 0.4 2.4 2 0 0 2 2 2 1 Proline-rich 19 DUF4407 PF14362.6 KFH45704.1 - 2.9 7.2 6.5 4.5 6.5 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KFH45704.1 - 7 5.3 4.9 12 4.6 4.9 1.3 1 0 0 1 1 1 0 Presenilin RMI1_N PF08585.12 KFH45707.1 - 2.3e-56 191.0 0.0 2.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein CBS PF00571.28 KFH45708.1 - 9.5e-18 64.4 1.9 8e-06 26.2 0.1 5.5 5 0 0 5 5 5 4 CBS domain AIM24 PF01987.17 KFH45709.1 - 7.5e-51 172.8 0.0 9.2e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF563 PF04577.14 KFH45710.1 - 9e-31 107.6 0.0 1.4e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CRAL_TRIO PF00650.20 KFH45711.1 - 8.2e-45 152.4 0.0 4.4e-44 150.0 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH45711.1 - 4.8e-15 55.5 0.1 4.8e-15 55.5 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFH45711.1 - 8.1e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adaptin_N PF01602.20 KFH45714.1 - 5e-136 454.3 2.8 6.9e-136 453.9 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFH45714.1 - 6.2e-63 211.7 2.8 9.1e-61 204.6 0.1 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFH45714.1 - 7.8e-16 58.2 1.3 7.8e-07 29.4 0.0 4.9 1 1 6 7 7 7 4 HEAT repeats HEAT PF02985.22 KFH45714.1 - 1.8e-11 43.3 4.5 0.022 15.0 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFH45714.1 - 5.3e-06 26.8 0.1 0.29 11.7 0.0 5.1 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 KFH45714.1 - 0.00012 22.0 0.1 0.49 10.4 0.1 2.8 2 0 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KFH45714.1 - 0.043 13.9 1.1 8.2 6.6 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KFH45714.1 - 0.096 12.2 0.0 2.2 7.8 0.0 2.8 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 KFH45714.1 - 0.1 12.8 0.7 5.9 7.1 0.0 3.7 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1805 PF08827.11 KFH45714.1 - 0.11 12.8 0.2 0.35 11.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF3446 PF11928.8 KFH45714.1 - 0.23 11.8 1.5 0.71 10.2 1.5 1.9 1 0 0 1 1 1 0 Early growth response N-terminal domain Glucan_synthase PF02364.15 KFH45715.1 - 0 1375.2 0.0 0 1374.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFH45715.1 - 2e-43 147.8 0.6 5.9e-43 146.3 0.6 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NIF3 PF01784.18 KFH45716.1 - 2.2e-59 201.1 0.0 2.8e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) baeRF_family3 PF18845.1 KFH45716.1 - 0.052 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 DUF2434 PF10361.9 KFH45717.1 - 9.3e-132 438.4 8.8 1.2e-131 438.1 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) TMEM171 PF15471.6 KFH45717.1 - 0.081 11.9 1.0 0.13 11.2 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Acetyltransf_10 PF13673.7 KFH45718.1 - 3.2e-10 40.0 0.0 4.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH45718.1 - 6.1e-08 32.9 0.0 2.4e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH45718.1 - 7e-07 29.6 0.0 1.4e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH45718.1 - 4.1e-06 26.9 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH45718.1 - 0.0033 17.4 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KFH45718.1 - 0.0037 17.0 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KFH45718.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase CSN8_PSD8_EIF3K PF10075.9 KFH45719.1 - 4.1e-37 127.4 0.0 5.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PRIMA1 PF16101.5 KFH45721.1 - 0.29 11.2 3.8 0.41 10.7 3.8 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cpn60_TCP1 PF00118.24 KFH45722.1 - 1.8e-160 534.9 0.7 2.1e-160 534.6 0.7 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.13 KFH45722.1 - 9.6e-43 146.3 0.1 3.9e-42 144.3 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Herpes_UL6 PF01763.16 KFH45722.1 - 0.25 9.8 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Exo_endo_phos PF03372.23 KFH45724.1 - 9.6e-09 35.1 0.1 2e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2985 PF11204.8 KFH45725.1 - 1.2e-21 76.6 3.5 2.2e-21 75.8 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) zf-H2C2 PF09337.10 KFH45726.1 - 2.8e-17 62.6 1.0 6.5e-17 61.5 1.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KFH45726.1 - 5.7e-11 42.4 0.1 5.7e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KFH45726.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KFH45726.1 - 0.0025 18.0 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TFIIA PF03153.13 KFH45726.1 - 0.33 10.9 9.7 0.52 10.3 9.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 KFH45726.1 - 1.2 7.2 12.1 2 6.4 12.1 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Gelsolin PF00626.22 KFH45728.1 - 7.7e-31 105.8 0.1 2e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Cpn60_TCP1 PF00118.24 KFH45729.1 - 2.9e-153 511.1 6.7 3.3e-153 510.9 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KFH45729.1 - 0.13 12.7 0.1 0.72 10.4 0.0 2.2 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 KFH45729.1 - 0.56 10.7 2.2 1.3 9.5 2.2 2.0 1 1 0 1 1 1 0 Cell division protein FtsA DASH_Dam1 PF08653.10 KFH45730.1 - 9e-29 99.1 2.8 1.2e-28 98.7 2.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 Thioesterase PF00975.20 KFH45731.1 - 7.3e-09 36.1 0.0 2.1e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFH45731.1 - 3.2e-06 27.9 0.5 3.8e-06 27.7 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFH45731.1 - 0.047 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFH45731.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aconitase PF00330.20 KFH45732.1 - 1.3e-147 492.5 0.0 1.7e-147 492.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFH45732.1 - 3.5e-43 147.1 0.0 5.8e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain I-set PF07679.16 KFH45732.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain GFA PF04828.14 KFH45733.1 - 0.00045 20.5 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_13 PF08421.11 KFH45733.1 - 0.23 11.8 2.4 14 6.0 0.2 2.7 2 1 0 2 2 2 0 Putative zinc binding domain Peptidase_S8 PF00082.22 KFH45734.1 - 2.9e-10 39.9 0.8 4.8e-08 32.6 0.2 2.5 1 1 2 3 3 3 2 Subtilase family Inhibitor_I9 PF05922.16 KFH45734.1 - 6.3e-05 23.6 0.0 0.002 18.7 0.0 2.7 2 1 0 2 2 2 1 Peptidase inhibitor I9 p450 PF00067.22 KFH45735.1 - 1.7e-57 195.2 0.0 2.4e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CLASP_N PF12348.8 KFH45736.1 - 3e-06 27.0 0.0 7.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 KFH45736.1 - 0.0012 18.9 0.7 1.2 9.6 0.1 4.5 5 0 0 5 5 4 1 HEAT repeat TAN PF11640.8 KFH45736.1 - 0.0045 17.1 0.2 0.02 15.0 0.0 2.3 2 1 0 2 2 1 1 Telomere-length maintenance and DNA damage repair HEAT_2 PF13646.6 KFH45736.1 - 0.0068 16.8 0.2 2.3 8.6 0.0 3.9 4 1 0 5 5 5 1 HEAT repeats CCDC144C PF14915.6 KFH45736.1 - 0.027 13.6 10.4 0.043 12.9 10.4 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Cnd1 PF12717.7 KFH45736.1 - 0.055 13.5 0.0 0.28 11.2 0.0 2.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Golgin_A5 PF09787.9 KFH45736.1 - 0.11 11.9 7.2 0.27 10.7 7.2 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_N PF10481.9 KFH45736.1 - 0.14 11.8 3.9 0.062 12.9 0.5 1.9 2 0 0 2 2 2 0 Cenp-F N-terminal domain HALZ PF02183.18 KFH45736.1 - 0.15 12.3 9.9 0.33 11.2 0.7 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 KFH45736.1 - 0.18 12.0 12.1 0.56 10.4 12.1 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APC_N_CC PF16689.5 KFH45736.1 - 0.84 9.7 5.0 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Baculo_PEP_C PF04513.12 KFH45736.1 - 1.1 9.3 4.5 20 5.2 2.0 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 KFH45736.1 - 1.6 8.3 9.6 3.3 7.4 9.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 KFH45736.1 - 3.5 6.9 11.8 7.2 5.9 10.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.12 KFH45736.1 - 4 6.7 7.6 17 4.7 2.4 2.3 1 1 0 2 2 2 0 CASP C terminal DUF1640 PF07798.11 KFH45736.1 - 4.2 7.4 15.5 14 5.7 12.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF812 PF05667.11 KFH45736.1 - 4.2 6.1 11.3 8.6 5.1 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 KFH45736.1 - 4.4 8.0 6.5 23 5.7 6.5 2.2 1 1 0 1 1 1 0 Initiation control protein YabA KLRAQ PF10205.9 KFH45736.1 - 4.4 7.6 9.4 11 6.3 1.6 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein BLOC1_2 PF10046.9 KFH45736.1 - 4.4 7.7 5.7 1.8 8.9 1.7 2.4 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KFH45736.1 - 4.7 7.3 12.1 12 5.9 12.1 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 KFH45736.1 - 6 7.0 11.8 0.084 13.0 2.7 2.4 3 0 0 3 3 2 0 TolA binding protein trimerisation Spc7 PF08317.11 KFH45736.1 - 8.1 5.2 10.3 1.4 7.8 4.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Glyco_transf_24 PF18404.1 KFH45737.1 - 2.3e-149 496.1 2.2 3.7e-149 495.4 2.2 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KFH45737.1 - 2.2e-64 217.9 1.0 2.5e-63 214.4 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KFH45737.1 - 2.2e-58 197.7 1.2 3.5e-55 187.2 0.2 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFH45737.1 - 1.6e-44 152.1 0.1 4.5e-44 150.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KFH45737.1 - 3.8e-43 146.7 0.1 4.7e-41 139.9 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFH45737.1 - 1.2e-41 141.3 0.0 2.1e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KFH45737.1 - 0.00017 21.3 0.1 0.00039 20.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 SHR-BD PF06650.12 KFH45738.1 - 3.2e-96 321.9 0.3 1.8e-94 316.1 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KFH45738.1 - 7.5e-95 316.8 9.1 1.5e-90 302.8 0.9 5.6 6 0 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KFH45738.1 - 1.7e-85 286.6 0.0 5e-83 278.5 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KFH45738.1 - 2.4e-75 252.2 7.4 1.4e-70 236.7 1.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KFH45738.1 - 1.6e-40 137.9 0.1 7.8e-40 135.6 0.1 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KFH45738.1 - 2.4e-07 31.0 0.1 9.1e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain TPR_1 PF00515.28 KFH45739.1 - 7.4e-24 82.5 27.9 0.00043 20.0 0.0 13.3 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 KFH45739.1 - 8.7e-24 83.8 23.5 0.0011 19.4 0.0 10.5 9 2 1 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFH45739.1 - 3.7e-22 77.1 38.2 0.027 15.3 0.0 14.8 13 1 2 15 15 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFH45739.1 - 8.8e-22 75.4 53.6 0.016 15.3 0.4 15.3 17 0 0 17 17 13 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFH45739.1 - 1.5e-21 76.7 54.8 0.0032 18.1 3.9 14.3 12 3 3 15 15 14 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFH45739.1 - 3.9e-21 73.8 15.2 0.33 11.4 0.0 15.2 17 0 0 17 17 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFH45739.1 - 2.1e-17 61.8 30.4 0.13 12.5 0.0 13.3 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFH45739.1 - 6.4e-17 61.0 20.8 0.0005 19.7 0.1 9.6 10 0 0 10 10 9 4 TPR repeat TPR_7 PF13176.6 KFH45739.1 - 5.6e-10 38.5 28.9 0.12 12.5 0.2 11.4 13 1 0 13 13 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFH45739.1 - 2.7e-09 37.2 52.4 0.028 14.7 0.2 12.9 14 3 0 15 15 13 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFH45739.1 - 9.5e-08 32.1 14.6 0.014 15.5 0.1 6.8 6 2 0 6 6 5 3 Tetratricopeptide repeat TPR_22 PF18833.1 KFH45739.1 - 7.6e-07 29.2 0.0 2.2e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH45739.1 - 0.00012 22.2 16.6 0.25 11.6 0.1 6.7 5 1 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFH45739.1 - 0.013 15.8 14.2 9.1 6.7 0.3 6.4 5 1 1 6 6 6 0 Tetratricopeptide repeat FIVAR PF07554.13 KFH45739.1 - 0.19 12.5 1.1 1.3 9.8 1.1 2.6 1 0 0 1 1 1 0 FIVAR domain Fis1_TPR_C PF14853.6 KFH45739.1 - 1 9.5 9.0 11 6.2 0.3 5.5 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KFH45739.1 - 2.4 9.0 39.1 10 7.0 0.0 13.8 17 0 0 17 17 15 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFH45739.1 - 3.7 7.5 26.7 2.1 8.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat HemY_N PF07219.13 KFH45739.1 - 5.9 7.1 21.0 0.34 11.1 0.2 6.3 7 0 0 7 7 7 0 HemY protein N-terminus Sel1 PF08238.12 KFH45739.1 - 7.2 7.5 6.5 17 6.3 0.1 4.6 5 0 0 5 5 4 0 Sel1 repeat Importin_rep_4 PF18808.1 KFH45740.1 - 8e-33 112.6 9.0 4.5e-32 110.2 2.5 4.6 4 1 1 5 5 5 1 Importin repeat Importin_rep_5 PF18816.1 KFH45740.1 - 5.3e-21 74.7 1.4 5.3e-21 74.7 1.4 3.2 3 0 0 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 KFH45740.1 - 2.1e-17 63.2 13.9 8.6e-10 38.9 0.6 8.7 8 2 2 10 10 8 3 HEAT-like repeat HEAT PF02985.22 KFH45740.1 - 4.3e-17 60.7 11.8 0.017 15.4 0.0 12.0 12 0 0 12 12 11 4 HEAT repeat Importin_rep_6 PF18829.1 KFH45740.1 - 2.6e-14 53.3 3.2 1.7e-13 50.6 0.3 3.4 3 0 0 3 3 3 1 Importin repeat 6 HEAT_2 PF13646.6 KFH45740.1 - 3.6e-13 49.7 15.5 0.00014 22.2 0.0 8.3 6 3 3 9 9 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KFH45740.1 - 1.1e-10 42.0 0.7 0.041 14.5 0.0 7.6 4 2 5 9 9 9 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KFH45740.1 - 1.4e-09 37.9 0.1 0.00052 19.8 0.1 5.1 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis DRIM PF07539.12 KFH45740.1 - 5.4e-07 28.3 5.2 0.0014 17.0 0.1 4.1 2 2 1 3 3 3 2 Down-regulated in metastasis CLASP_N PF12348.8 KFH45740.1 - 9.6e-07 28.6 3.7 0.14 11.7 0.1 6.1 4 2 1 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 KFH45740.1 - 2.7e-06 26.8 0.1 2.7e-06 26.8 0.1 4.2 4 2 0 5 5 5 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KFH45740.1 - 0.0012 18.9 4.7 4.5 7.3 0.0 5.9 6 2 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CAS_CSE1 PF03378.15 KFH45740.1 - 0.0017 16.9 0.2 3.3 6.1 0.1 3.9 2 1 2 4 4 4 1 CAS/CSE protein, C-terminus V-ATPase_H_N PF03224.14 KFH45740.1 - 0.0042 16.4 4.7 0.16 11.3 0.1 3.1 2 1 1 3 3 3 1 V-ATPase subunit H UNC45-central PF11701.8 KFH45740.1 - 0.0063 16.5 4.8 3.5 7.6 0.2 4.3 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central IBN_N PF03810.19 KFH45740.1 - 0.0088 15.9 1.4 0.065 13.1 0.1 3.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain TFCD_C PF12612.8 KFH45740.1 - 0.012 15.4 0.1 0.3 10.9 0.0 3.2 2 2 1 4 4 4 0 Tubulin folding cofactor D C terminal Telomere_reg-2 PF10193.9 KFH45740.1 - 0.016 15.6 1.3 0.016 15.6 1.3 4.6 5 1 1 6 6 5 0 Telomere length regulation protein FdhE PF04216.12 KFH45740.1 - 0.018 14.9 0.8 0.018 14.9 0.8 3.8 3 1 0 3 3 3 0 Protein involved in formate dehydrogenase formation DUF3535 PF12054.8 KFH45740.1 - 0.029 13.6 3.2 0.092 12.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) DNA_alkylation PF08713.11 KFH45740.1 - 0.076 12.7 2.9 0.27 10.9 0.1 3.0 3 1 0 3 3 3 0 DNA alkylation repair enzyme DUF3713 PF12506.8 KFH45740.1 - 0.16 12.3 0.0 5.5 7.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) Phage_term_smal PF05944.12 KFH45740.1 - 0.35 10.9 2.8 15 5.5 0.1 3.7 3 0 0 3 3 3 0 Phage small terminase subunit RTP1_C1 PF10363.9 KFH45740.1 - 0.63 10.2 3.1 5.7 7.2 0.1 4.1 4 2 0 4 4 2 0 Required for nuclear transport of RNA pol II C-terminus 1 GlutR_dimer PF00745.20 KFH45740.1 - 0.92 10.0 5.2 2.7 8.5 0.0 4.2 5 0 0 5 5 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Arm PF00514.23 KFH45740.1 - 8.5 6.6 10.0 7 6.9 0.0 4.7 6 0 0 6 6 4 0 Armadillo/beta-catenin-like repeat CBS PF00571.28 KFH45741.1 - 2.9e-35 120.5 8.5 2.6e-09 37.4 0.0 6.0 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KFH45741.1 - 2.4e-09 37.0 0.0 8.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 PB1 domain Sugar_tr PF00083.24 KFH45742.1 - 1.5e-71 241.6 9.7 2.1e-71 241.2 9.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45742.1 - 1.4e-14 53.8 29.3 1.4e-14 53.8 29.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily HxlR PF01638.17 KFH45743.1 - 0.011 15.5 0.1 15 5.5 0.0 3.2 3 0 0 3 3 3 0 HxlR-like helix-turn-helix Kinesin PF00225.23 KFH45744.1 - 8.1e-82 274.8 0.0 1.2e-81 274.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFH45744.1 - 1.4e-21 77.0 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding PBP1_TM PF14812.6 KFH45744.1 - 7.3 7.0 9.4 0.4 11.1 2.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2_2 PF13465.6 KFH45745.1 - 7e-09 35.7 7.9 0.0014 19.0 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFH45745.1 - 9.1e-09 35.3 17.5 0.0037 17.7 2.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH45745.1 - 0.00013 22.5 15.5 0.18 12.7 2.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFH45745.1 - 0.00062 20.0 1.2 0.0023 18.2 1.2 2.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFH45745.1 - 0.0044 17.0 5.8 0.077 13.0 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-UBR PF02207.20 KFH45745.1 - 2.4 8.4 7.0 4.8 7.4 7.0 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) BolA PF01722.18 KFH45746.1 - 1.8e-21 76.2 0.0 4.7e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Aminotran_1_2 PF00155.21 KFH45747.1 - 1.8e-33 116.2 0.0 2.1e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFH45747.1 - 0.0077 14.8 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SnAPC_2_like PF11035.8 KFH45747.1 - 0.02 15.0 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Mog1 PF04603.12 KFH45748.1 - 5.6e-39 133.7 0.0 6.8e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Vps51 PF08700.11 KFH45749.1 - 4.2e-29 100.5 0.0 7.3e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KFH45749.1 - 0.0034 17.6 0.1 0.0053 16.9 0.1 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KFH45749.1 - 0.0037 16.0 0.1 0.0047 15.7 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family SPX PF03105.19 KFH45749.1 - 0.054 13.4 2.6 0.069 13.1 2.6 1.2 1 0 0 1 1 1 0 SPX domain ArgoN PF16486.5 KFH45749.1 - 0.072 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of argonaute Vps53_N PF04100.12 KFH45749.1 - 0.2 10.6 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Vps53-like, N-terminal DUF4106 PF13388.6 KFH45749.1 - 0.73 9.0 7.9 1.1 8.5 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAP_N PF01213.19 KFH45749.1 - 1.7 8.1 9.8 4.3 6.7 9.4 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pex14_N PF04695.13 KFH45749.1 - 5.1 7.7 12.6 1.1 9.9 8.4 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprT-like PF10263.9 KFH45750.1 - 2.8e-39 133.5 2.6 5.3e-39 132.6 2.6 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KFH45750.1 - 1.2e-10 41.1 3.7 2e-10 40.4 3.7 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 KFH45750.1 - 8.2e-05 22.9 0.1 0.00023 21.5 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box CHDNT PF08073.12 KFH45750.1 - 0.0013 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain Zn-ribbon_8 PF09723.10 KFH45750.1 - 0.0047 17.0 1.5 0.012 15.7 1.5 1.7 1 0 0 1 1 1 1 Zinc ribbon domain YABBY PF04690.13 KFH45750.1 - 0.0053 17.3 3.4 0.0083 16.7 0.1 2.7 2 0 0 2 2 2 1 YABBY protein DUF4379 PF14311.6 KFH45750.1 - 0.21 12.0 4.7 0.74 10.2 4.7 2.0 1 0 0 1 1 1 0 Probable Zinc-ribbon domain PKI PF02827.16 KFH45750.1 - 3.3 8.0 9.0 3.8 7.8 0.3 2.8 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor XFP_N PF09364.10 KFH45751.1 - 1.7e-167 556.8 0.0 2.2e-167 556.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KFH45751.1 - 5.3e-80 267.7 0.0 7.8e-80 267.1 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KFH45751.1 - 2.1e-78 262.1 0.0 3.3e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DNA_ligase_A_M PF01068.21 KFH45752.1 - 9.7e-51 172.3 0.1 3.7e-48 163.9 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFH45752.1 - 5.7e-35 121.2 0.0 1.3e-34 120.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFH45752.1 - 5.3e-21 75.1 0.0 2.5e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFH45752.1 - 0.00025 21.4 0.0 0.0005 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase CSN8_PSD8_EIF3K PF10075.9 KFH45753.1 - 2.4e-19 69.7 0.0 6.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KFH45753.1 - 0.0042 16.5 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family COG5 PF10392.9 KFH45754.1 - 4.6e-37 127.1 2.0 1e-36 126.0 0.3 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF4470 PF14737.6 KFH45756.1 - 2e-20 72.8 0.0 4.3e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KFH45756.1 - 7.2e-12 45.2 13.3 1.6e-11 44.1 13.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KFH45756.1 - 1.3 9.4 6.6 3.5 8.0 6.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PAP2 PF01569.21 KFH45757.1 - 8.2e-21 74.2 2.8 8.2e-21 74.2 2.8 2.7 2 1 0 2 2 2 1 PAP2 superfamily AIRC PF00731.20 KFH45758.1 - 8.7e-60 200.6 0.7 2.2e-59 199.3 0.7 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KFH45758.1 - 1.7e-49 167.7 0.0 2.6e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KFH45758.1 - 2.7e-14 52.6 0.0 6.8e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KFH45758.1 - 0.0014 18.2 0.0 0.0044 16.6 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 KFH45758.1 - 0.0033 17.9 0.1 0.76 10.3 0.0 2.7 2 0 0 2 2 2 1 XdhC Rossmann domain Epimerase PF01370.21 KFH45758.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KFH45758.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 KFH45760.1 - 0.00012 22.3 12.1 0.0022 18.3 0.5 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KFH45760.1 - 0.0016 19.0 1.5 0.0046 17.5 0.2 2.2 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KFH45760.1 - 0.016 15.6 1.1 0.016 15.6 1.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH45760.1 - 0.052 14.4 0.4 0.052 14.4 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KFH45760.1 - 0.084 13.3 6.6 0.37 11.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Integrin_B_tail PF07965.12 KFH45760.1 - 0.098 13.2 0.9 0.18 12.3 0.4 1.6 1 1 1 2 2 2 0 Integrin beta tail domain Choline_kinase PF01633.20 KFH45761.1 - 9.2e-50 169.2 0.0 4.9e-49 166.8 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KFH45761.1 - 1.1e-11 45.2 2.9 1.2e-11 45.0 1.7 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFH45761.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFH45761.1 - 0.0031 16.9 0.0 0.0071 15.7 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase 14-3-3 PF00244.20 KFH45762.1 - 6e-107 356.2 2.5 7.1e-107 356.0 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein Gp-FAR-1 PF05823.12 KFH45762.1 - 0.073 13.4 0.9 0.26 11.6 0.6 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fungal_trans PF04082.18 KFH45763.1 - 1.8e-20 73.1 0.2 2.7e-20 72.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45763.1 - 8.7e-09 35.4 8.9 2.2e-08 34.1 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 KFH45764.1 - 0.062 13.7 2.5 2.9 8.3 0.2 3.4 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-met PF12874.7 KFH45764.1 - 0.88 10.1 6.5 1.4 9.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFH45764.1 - 0.93 10.5 31.1 2.8 9.0 0.2 7.2 7 1 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH45764.1 - 5.6 7.4 7.2 34 4.9 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SBDS PF01172.18 KFH45765.1 - 4.9e-23 81.0 0.0 5.7e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SYF2 PF08231.12 KFH45765.1 - 0.067 13.6 0.0 0.072 13.5 0.0 1.1 1 0 0 1 1 1 0 SYF2 splicing factor MbtH PF03621.13 KFH45765.1 - 0.074 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 MbtH-like protein Pkinase PF00069.25 KFH45766.1 - 8.7e-61 205.6 0.0 1.6e-38 132.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45766.1 - 3.1e-27 95.5 0.0 2.3e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KFH45766.1 - 1.6e-15 57.3 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KFH45766.1 - 7.5e-07 28.8 0.0 0.00041 19.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFH45766.1 - 6.5e-05 23.0 0.0 0.0032 17.4 0.1 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH45766.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFH45766.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFH45766.1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L35Ae PF01247.18 KFH45767.1 - 5.7e-40 135.4 0.2 6.7e-40 135.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KFH45767.1 - 3.6e-05 23.9 0.1 0.031 14.5 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Acetate_kinase PF00871.17 KFH45768.1 - 1.9e-88 296.8 0.0 2.2e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Lyx_isomer PF07385.12 KFH45768.1 - 0.071 12.4 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 D-lyxose isomerase RIC1 PF07064.13 KFH45769.1 - 6.5e-92 307.5 0.2 8.8e-92 307.1 0.2 1.2 1 0 0 1 1 1 1 RIC1 Med14 PF08638.11 KFH45770.1 - 3.8e-65 218.9 0.0 6e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 zf-CCCH_2 PF14608.6 KFH45771.1 - 1.8e-12 47.2 62.5 0.00073 19.9 15.0 5.5 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KFH45771.1 - 0.0079 16.5 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Sporozoite_P67 PF05642.11 KFH45771.1 - 0.011 13.9 0.0 0.024 12.7 0.0 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 KFH45772.1 - 4.7e-60 203.2 0.0 1.8e-59 201.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45772.1 - 4.8e-35 121.1 0.0 7.9e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KFH45772.1 - 0.00035 20.7 0.0 0.6 10.3 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 KFH45772.1 - 0.00099 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFH45772.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFH45772.1 - 0.032 13.0 0.0 0.032 13.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Proteasome PF00227.26 KFH45773.1 - 1.6e-39 135.4 0.0 1.9e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SH3_6 PF12913.7 KFH45774.1 - 0.096 12.2 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) Aminotran_1_2 PF00155.21 KFH45775.1 - 3.9e-16 59.2 0.0 5.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFH45775.1 - 4.4e-07 29.1 0.0 9.3e-07 28.0 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KFH45775.1 - 0.047 13.0 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L36e PF01158.18 KFH45776.1 - 1.6e-41 140.4 6.1 1.8e-41 140.3 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KFH45776.1 - 0.022 14.8 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.9 KFH45776.1 - 0.06 13.5 2.5 0.058 13.5 1.6 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.12 KFH45776.1 - 0.097 12.5 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 LemA family PRA-PH PF01503.17 KFH45776.1 - 0.11 13.0 0.1 0.47 10.9 0.1 1.9 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF2207 PF09972.9 KFH45776.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) La PF05383.17 KFH45777.1 - 1.4e-14 53.9 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 La domain Lipase_3 PF01764.25 KFH45778.1 - 1.2e-31 109.5 0.0 1.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFH45778.1 - 5.8e-06 27.1 0.2 8.2e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH45778.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFH45778.1 - 5.3e-05 23.4 0.0 8.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KFH45778.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KFH45778.1 - 0.0061 16.1 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.20 KFH45778.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 KFH45778.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KFH45778.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TerB PF05099.13 KFH45779.1 - 0.057 13.4 2.6 0.21 11.5 2.6 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TerB DUF533 PF04391.12 KFH45779.1 - 3.2 7.3 22.3 1.4 8.5 1.6 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF533) SbcCD_C PF13558.6 KFH45779.1 - 5.8 7.2 7.4 2.8 8.2 0.3 3.6 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit SR-25 PF10500.9 KFH45780.1 - 0.00048 19.8 2.3 0.00059 19.5 2.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Equine_IAV_S2 PF06502.11 KFH45780.1 - 0.87 9.7 2.4 2 8.6 2.4 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein ADH_N PF08240.12 KFH45781.1 - 1.8e-26 92.2 0.7 3.2e-26 91.3 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH45781.1 - 1.1e-17 64.2 0.1 9.2e-17 61.2 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH45781.1 - 1.9e-06 27.5 0.0 5.6e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFH45781.1 - 8.1e-05 23.7 0.0 0.00018 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFH45781.1 - 0.0025 17.2 0.2 0.0042 16.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KFH45781.1 - 0.028 13.6 0.2 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KFH45781.1 - 0.059 14.1 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KFH45781.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFH45781.1 - 0.17 11.5 0.2 0.26 10.9 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Asp_decarbox PF02261.16 KFH45781.1 - 0.2 11.6 0.1 0.81 9.6 0.0 1.9 2 0 0 2 2 2 0 Aspartate decarboxylase Pyr_redox PF00070.27 KFH45781.1 - 0.35 11.5 1.3 4 8.1 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Suf PF05843.14 KFH45782.1 - 0.00048 20.2 6.3 0.0019 18.2 0.2 2.9 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFH45782.1 - 0.53 11.3 0.1 0.53 11.3 0.1 7.1 6 3 4 10 10 10 0 Tetratricopeptide repeat VMA21 PF09446.10 KFH45783.1 - 1.5e-14 53.8 10.4 2.2e-14 53.3 10.4 1.2 1 0 0 1 1 1 1 VMA21-like domain Zn_clus PF00172.18 KFH45784.1 - 2.9e-10 40.1 10.0 6.1e-10 39.1 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH45784.1 - 2.3e-07 30.1 0.4 3.7e-07 29.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain peroxidase PF00141.23 KFH45785.1 - 8.4e-50 169.6 0.0 1.3e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase E1-E2_ATPase PF00122.20 KFH45786.1 - 1.6e-50 171.2 3.9 1.6e-49 167.9 1.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH45786.1 - 1.7e-45 154.9 4.6 1.7e-45 154.9 4.6 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KFH45786.1 - 1.2e-20 72.9 0.0 3.1e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFH45786.1 - 1.9e-20 74.1 2.2 5.5e-20 72.6 1.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH45786.1 - 1.6e-18 66.6 0.0 3.7e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFH45786.1 - 2.7e-07 30.6 1.1 5e-06 26.4 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFH45786.1 - 0.00034 21.1 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase eIF-3_zeta PF05091.12 KFH45787.1 - 3.4e-204 679.7 0.0 4.1e-204 679.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KFH45787.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF569) CDC48_2 PF02933.17 KFH45787.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GRP PF07172.11 KFH45787.1 - 2.3 9.0 14.9 6.5 7.5 14.9 1.7 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L2_C PF03947.18 KFH45788.1 - 1.2e-49 167.7 4.2 1.2e-49 167.7 4.2 2.1 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFH45788.1 - 3.6e-25 87.7 0.5 9.9e-25 86.3 0.3 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PEP-utilizers PF00391.23 KFH45788.1 - 0.12 12.1 0.2 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain NPR3 PF03666.13 KFH45789.1 - 1e-146 489.4 2.0 5.1e-146 487.1 2.0 1.9 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 EC042_2821 PF18740.1 KFH45789.1 - 0.027 14.3 0.6 0.046 13.6 0.6 1.3 1 0 0 1 1 1 0 EC042_2821-lke REase CaM_binding PF07839.11 KFH45789.1 - 0.077 13.7 0.3 0.077 13.7 0.3 2.0 2 0 0 2 2 2 0 Plant calmodulin-binding domain Chitin_synth_2 PF03142.15 KFH45790.1 - 2.8e-290 963.4 0.1 3.6e-290 963.0 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFH45790.1 - 2.5e-13 50.4 1.4 7.1e-13 48.9 1.4 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFH45790.1 - 2.4e-08 34.1 0.1 1e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFH45790.1 - 0.00059 19.4 0.0 0.0083 15.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFH45790.1 - 0.011 15.6 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 NepR PF18557.1 KFH45790.1 - 0.11 12.2 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Anti-sigma factor NepR OPA3 PF07047.12 KFH45791.1 - 3.7e-47 159.2 0.5 3.7e-47 159.2 0.5 1.8 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) EzrA PF06160.12 KFH45791.1 - 0.0012 17.2 0.5 0.0015 16.8 0.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4795 PF16043.5 KFH45791.1 - 0.0029 17.2 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) FTCD_C PF04961.12 KFH45791.1 - 0.022 14.5 0.3 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF3450 PF11932.8 KFH45791.1 - 0.039 13.2 3.6 0.059 12.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 KFH45791.1 - 0.044 14.2 0.5 0.044 14.2 0.5 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Wbp11 PF09429.10 KFH45791.1 - 0.05 14.0 16.0 0.39 11.2 6.6 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 Snapin_Pallidin PF14712.6 KFH45791.1 - 0.07 13.5 3.0 0.14 12.5 3.0 1.5 1 0 0 1 1 1 0 Snapin/Pallidin CAF-1_p150 PF11600.8 KFH45791.1 - 0.24 11.1 20.7 0.2 11.4 9.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.13 KFH45791.1 - 0.25 10.6 0.9 0.41 9.9 0.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 KFH45791.1 - 0.39 10.9 5.5 0.81 9.9 5.5 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Med21 PF11221.8 KFH45791.1 - 2 8.6 11.4 13 6.1 8.2 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ZapB PF06005.12 KFH45791.1 - 3.8 8.0 14.0 2.1 8.9 10.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 KFH45791.1 - 6.7 7.4 11.0 1.5 9.5 7.2 1.9 2 0 0 2 2 2 0 SlyX CK_II_beta PF01214.18 KFH45792.1 - 3.4e-77 258.4 0.1 4.1e-77 258.1 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nop PF01798.18 KFH45794.1 - 3.2e-68 229.6 0.0 6.2e-68 228.7 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KFH45794.1 - 3.8e-46 156.9 1.1 1.2e-45 155.3 1.1 1.9 1 0 0 1 1 1 1 Prp31 C terminal domain Sugar_tr PF00083.24 KFH45795.1 - 2.5e-23 82.7 20.6 9.3e-16 57.7 6.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 KFH45795.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) RhoGEF PF00621.20 KFH45796.1 - 6.2e-20 72.2 0.0 1.1e-19 71.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain WD40 PF00400.32 KFH45797.1 - 6.6e-23 80.6 3.9 2.4e-05 25.0 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45797.1 - 1.7e-14 53.9 0.0 0.032 14.5 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH45797.1 - 0.0004 20.3 0.1 0.39 10.6 0.1 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFH45797.1 - 0.00075 18.3 0.4 0.088 11.4 0.1 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KFH45797.1 - 0.0014 17.8 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 KFH45797.1 - 0.012 14.6 0.3 3.2 6.6 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KFH45797.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 KFH45797.1 - 0.1 11.1 0.0 4.3 5.7 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KFH45797.1 - 0.41 10.6 2.1 7.6 6.6 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2406 PF10295.9 KFH45800.1 - 6e-26 90.9 0.3 6e-26 90.9 0.3 2.9 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) Gal_mutarotas_2 PF13802.6 KFH45800.1 - 0.072 13.4 0.5 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Galactose mutarotase-like G6PD_C PF02781.16 KFH45801.1 - 1.6e-113 378.8 0.0 2.4e-113 378.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFH45801.1 - 3.3e-48 164.6 0.1 2.1e-47 162.0 0.1 2.1 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GST_N_3 PF13417.6 KFH45802.1 - 5.4e-17 62.0 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFH45802.1 - 2.6e-13 50.1 0.0 4.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFH45802.1 - 3.9e-09 36.7 0.0 9.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFH45802.1 - 4.2e-05 23.5 1.1 6.1e-05 23.0 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFH45802.1 - 0.0024 18.4 0.0 0.0048 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH45802.1 - 0.0055 16.9 0.5 0.045 14.0 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFH45802.1 - 0.11 12.7 0.1 0.9 9.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF5053 PF16476.5 KFH45802.1 - 0.12 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Spt20 PF12090.8 KFH45802.1 - 0.68 9.5 9.0 1.1 8.8 9.0 1.3 1 0 0 1 1 1 0 Spt20 family MDFI PF15316.6 KFH45802.1 - 5 7.2 5.2 8.3 6.5 4.4 1.8 1 1 1 2 2 2 0 MyoD family inhibitor DUF4646 PF15496.6 KFH45803.1 - 0.0059 17.2 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF759 PF05537.11 KFH45803.1 - 0.016 14.1 0.5 0.021 13.7 0.5 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Sel1 PF08238.12 KFH45804.1 - 2.3e-40 136.1 29.2 9.8e-06 26.1 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 KFH45804.1 - 0.14 12.4 0.2 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Amino_oxidase PF01593.24 KFH45805.1 - 1.9e-19 70.3 0.0 5.4e-19 68.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH45805.1 - 3.8e-10 39.8 0.1 1.2e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH45805.1 - 1.2e-07 31.6 0.0 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFH45805.1 - 0.0014 17.9 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 KFH45805.1 - 0.018 13.8 0.0 0.54 9.0 0.0 2.2 2 0 0 2 2 2 0 MCRA family Pyr_redox_2 PF07992.14 KFH45805.1 - 0.02 14.1 0.1 0.051 12.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH45805.1 - 0.12 12.3 0.2 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HLH PF00010.26 KFH45806.1 - 2e-11 43.7 0.0 6.1e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain p450 PF00067.22 KFH45807.1 - 2.7e-65 220.9 0.0 3.8e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mistic PF11458.8 KFH45807.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Membrane-integrating protein Mistic TUG-UBL1 PF11470.8 KFH45808.1 - 3.9e-25 87.9 0.0 7.9e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KFH45808.1 - 0.0011 19.0 0.1 0.0097 16.0 0.1 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF4294 PF14127.6 KFH45808.1 - 0.0061 16.5 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Got1 PF04178.12 KFH45811.1 - 1.9e-34 118.5 17.8 2.5e-34 118.1 17.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Syja_N PF02383.18 KFH45813.1 - 1.5e-71 241.4 0.0 3.1e-71 240.3 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KFH45813.1 - 9.9e-11 41.6 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF2_N PF00176.23 KFH45814.1 - 5.2e-49 166.8 0.0 7.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH45814.1 - 2.2e-16 60.2 0.1 1.2e-15 57.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH45814.1 - 2.1e-05 24.6 0.0 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFH45814.1 - 0.00011 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 KFH45814.1 - 0.00017 21.4 0.1 0.00039 20.3 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KFH45814.1 - 0.0037 17.1 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain HBS1_N PF08938.10 KFH45814.1 - 0.009 16.3 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 HBS1 N-terminus HHH_3 PF12836.7 KFH45814.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF601 PF04642.12 KFH45814.1 - 1.1 8.7 7.6 2.8 7.3 7.6 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF601 bZIP_1 PF00170.21 KFH45815.1 - 0.00012 22.1 10.8 0.00022 21.2 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KFH45815.1 - 0.021 15.4 0.1 0.041 14.5 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 KFH45815.1 - 0.064 13.6 0.3 1.5 9.2 0.8 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 KFH45815.1 - 0.31 11.2 6.3 0.5 10.6 6.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.15 KFH45815.1 - 0.67 10.1 13.4 3.8 7.7 13.4 2.2 1 1 0 1 1 1 0 Basic region leucine zipper PAP1 PF08601.10 KFH45815.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.1 2 1 0 2 2 2 0 Transcription factor PAP1 Pyr_redox_2 PF07992.14 KFH45817.1 - 5.5e-17 61.9 0.0 1.3e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH45817.1 - 1.3e-13 50.8 0.0 5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH45817.1 - 1.8e-13 50.3 0.0 7.9e-10 38.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFH45817.1 - 4.6e-13 48.4 0.0 5.1e-09 35.1 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH45817.1 - 6.4e-06 26.3 0.0 2.5e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH45817.1 - 2.3e-05 24.9 0.6 0.017 15.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH45817.1 - 2.9e-05 23.5 0.4 0.00034 20.0 1.0 2.1 1 1 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KFH45817.1 - 4.3e-05 23.6 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KFH45817.1 - 0.00011 22.0 0.2 0.0024 17.5 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH45817.1 - 0.0011 18.1 4.1 0.0022 17.2 0.7 2.5 2 1 1 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KFH45817.1 - 0.0012 18.0 0.1 0.0034 16.5 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KFH45817.1 - 0.0017 17.7 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KFH45817.1 - 0.0022 18.0 0.2 0.3 11.1 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KFH45817.1 - 0.0044 17.4 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KFH45817.1 - 0.005 15.6 0.3 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein F420_oxidored PF03807.17 KFH45817.1 - 0.018 15.6 0.0 3.4 8.3 0.0 3.4 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KFH45817.1 - 0.019 15.2 0.1 0.061 13.6 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain GIDA PF01134.22 KFH45817.1 - 0.021 13.9 0.1 0.26 10.4 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF4147 PF13660.6 KFH45817.1 - 0.029 13.9 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Amino_oxidase PF01593.24 KFH45817.1 - 0.066 12.5 0.2 0.16 11.2 0.2 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KFH45817.1 - 0.071 12.3 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KFH45817.1 - 0.13 11.9 0.2 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KFH45817.1 - 0.18 11.1 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 ThiF family C1_2 PF03107.16 KFH45818.1 - 0.29 11.5 8.9 0.49 10.7 8.9 1.3 1 0 0 1 1 1 0 C1 domain Cyclin_N PF00134.23 KFH45819.1 - 3.7e-43 146.3 0.0 8.8e-43 145.1 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFH45819.1 - 8.2e-35 119.5 0.0 1.5e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain CDC27 PF09507.10 KFH45819.1 - 4.9 6.4 21.3 6.8 6.0 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Erythro_esteras PF05139.14 KFH45820.1 - 7.6e-118 394.3 0.6 9.6e-118 393.9 0.6 1.1 1 0 0 1 1 1 1 Erythromycin esterase PSP PF04046.16 KFH45820.1 - 0.072 13.0 0.1 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 PSP Rho_N PF07498.12 KFH45821.1 - 0.018 14.9 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain PV-1 PF06637.11 KFH45821.1 - 0.056 12.3 0.6 0.1 11.4 0.6 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) KfrA_N PF11740.8 KFH45821.1 - 4 8.1 10.9 5 7.8 5.8 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term ICL PF00463.21 KFH45822.1 - 1.3e-294 977.6 1.2 1.5e-294 977.4 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFH45822.1 - 1e-10 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.25 KFH45823.1 - 9.4e-63 212.0 0.0 1.3e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45823.1 - 1.8e-38 132.3 0.0 2.3e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH45823.1 - 1.7e-05 24.3 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFH45823.1 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFH45823.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain AMPK1_CBM PF16561.5 KFH45824.1 - 0.00081 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase FlgH PF02107.16 KFH45824.1 - 0.067 12.8 4.4 0.13 11.9 4.4 1.4 1 0 0 1 1 1 0 Flagellar L-ring protein Presenilin PF01080.17 KFH45824.1 - 0.45 9.2 3.6 0.47 9.2 3.6 1.2 1 0 0 1 1 1 0 Presenilin Sec3_C PF09763.9 KFH45824.1 - 0.89 7.9 4.9 0.99 7.7 4.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Polyoma_lg_T_C PF06431.11 KFH45824.1 - 8.9 5.1 6.3 16 4.3 6.3 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus GEMIN8 PF15348.6 KFH45824.1 - 9.8 6.4 10.6 0.91 9.8 4.7 1.9 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 FUSC_2 PF13515.6 KFH45825.1 - 1.1e-23 83.7 9.0 1.1e-23 83.7 9.0 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KFH45825.1 - 1.1e-09 37.4 3.1 2.8e-07 29.5 1.8 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 KFH45825.1 - 1.4e-05 24.4 0.1 1.4e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 KFH45825.1 - 0.0049 15.8 15.9 0.16 10.8 10.8 3.9 3 2 1 4 4 4 1 Aluminium activated malate transporter ArAE_2 PF10334.9 KFH45825.1 - 0.038 13.8 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KFH45825.1 - 0.038 13.1 6.4 0.5 9.4 0.3 2.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Amidohydro_2 PF04909.14 KFH45826.1 - 3.3e-23 82.9 0.1 1.8e-21 77.2 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase Transglut_N PF00868.20 KFH45826.1 - 0.18 12.2 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase family HSA PF07529.13 KFH45826.1 - 2.8 8.3 0.0 2.8 8.3 0.0 2.7 3 0 0 3 3 3 0 HSA Snf7 PF03357.21 KFH45827.1 - 1.3e-32 112.7 20.1 1.3e-32 112.7 20.1 2.0 1 1 1 2 2 2 1 Snf7 Peptidase_A3 PF02160.15 KFH45827.1 - 0.097 12.1 0.9 0.15 11.6 0.9 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) DUF3138 PF11336.8 KFH45827.1 - 0.27 9.8 6.5 0.3 9.6 4.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Speriolin_C PF15059.6 KFH45827.1 - 0.46 10.6 3.5 0.83 9.8 1.2 2.0 1 1 1 2 2 2 0 Speriolin C-terminus Allexi_40kDa PF05549.11 KFH45827.1 - 0.7 9.3 6.5 1.2 8.6 6.5 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein CMD PF02627.20 KFH45828.1 - 3.9e-09 36.5 0.4 5.3e-08 32.8 0.2 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family KilA-N PF04383.13 KFH45829.1 - 0.00023 21.0 0.0 0.0049 16.7 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain CDC50 PF03381.15 KFH45830.1 - 5e-98 328.0 0.0 6.2e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PTCB-BRCT PF12738.7 KFH45832.1 - 4e-05 23.5 0.0 9.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFH45832.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pneumo_att_G PF05539.11 KFH45834.1 - 0.24 10.9 8.0 0.22 11.1 7.9 1.2 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4805 PF16063.5 KFH45834.1 - 8.3 5.7 8.8 14 4.9 8.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) CFEM PF05730.11 KFH45836.1 - 0.081 13.0 2.3 0.14 12.2 2.3 1.4 1 0 0 1 1 1 0 CFEM domain Pex24p PF06398.11 KFH45837.1 - 1.1e-91 307.6 0.1 1.3e-91 307.3 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KFH45837.1 - 0.0015 17.0 3.4 0.023 13.1 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Metal_resist PF13801.6 KFH45837.1 - 0.0064 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal resistance Reticulon PF02453.17 KFH45837.1 - 0.0069 16.4 1.9 0.035 14.1 0.1 2.2 1 1 0 2 2 2 1 Reticulon Phageshock_PspG PF09583.10 KFH45837.1 - 0.031 14.5 2.5 0.084 13.2 2.5 1.7 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) ArsA_ATPase PF02374.15 KFH45838.1 - 1.5e-107 359.3 0.0 1.8e-107 359.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KFH45838.1 - 1.8e-12 47.5 0.0 4.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFH45838.1 - 1.9e-12 47.3 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KFH45838.1 - 7.1e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KFH45838.1 - 3.9e-05 23.3 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KFH45838.1 - 6e-05 22.6 0.1 0.00028 20.4 0.0 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KFH45838.1 - 0.00017 21.3 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KFH45838.1 - 0.061 12.9 0.2 0.11 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH45838.1 - 0.066 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rep_fac-A_C PF08646.10 KFH45839.1 - 2e-53 180.1 1.5 1.1e-52 177.6 0.9 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFH45839.1 - 1.6e-36 124.1 1.3 3.9e-36 122.9 0.6 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KFH45839.1 - 2.4e-21 75.7 0.0 4.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFH45839.1 - 1e-13 51.0 0.2 2.9e-09 36.8 0.0 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KFH45839.1 - 1.3e-07 31.6 0.2 2.3e-05 24.3 0.1 3.0 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 KFH45839.1 - 0.0034 15.9 0.1 0.0052 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) zf-like PF04071.12 KFH45839.1 - 0.019 14.8 0.3 0.052 13.5 0.3 1.7 1 0 0 1 1 1 0 Cysteine-rich small domain Herpes_UL52 PF03121.15 KFH45839.1 - 0.027 14.4 0.1 0.072 13.0 0.1 1.7 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase ADH_zinc_N PF00107.26 KFH45840.1 - 3.3e-26 91.8 0.1 6.3e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH45840.1 - 1.3e-24 87.8 0.0 2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH45840.1 - 2.7e-08 33.6 0.0 7.4e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain SH2_2 PF14633.6 KFH45841.1 - 1.1e-84 283.1 0.0 2.6e-84 282.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KFH45841.1 - 5.6e-40 136.4 0.4 1.6e-39 134.9 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KFH45841.1 - 7.4e-30 103.7 0.0 2.7e-29 101.9 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KFH45841.1 - 9.2e-30 103.1 0.0 2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KFH45841.1 - 5e-19 68.7 32.9 5e-19 68.7 32.9 6.3 4 2 2 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KFH45841.1 - 1.1e-06 29.4 3.8 1.8e-05 25.6 2.0 3.8 3 1 0 3 3 3 1 HHH domain SH2 PF00017.24 KFH45841.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KFH45841.1 - 0.0041 17.3 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 KFH45841.1 - 0.11 12.9 0.0 0.39 11.2 0.0 2.0 1 1 0 1 1 1 0 Tex protein YqgF-like domain Peptidase_M20 PF01546.28 KFH45842.1 - 7.6e-34 117.2 0.1 1.2e-33 116.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFH45842.1 - 8.9e-12 44.9 0.0 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain FUSC PF04632.12 KFH45842.1 - 0.35 9.4 4.4 0.46 9.0 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-U1 PF06220.12 KFH45843.1 - 1.4e-17 63.2 3.1 2.2e-17 62.5 3.1 1.3 1 0 0 1 1 1 1 U1 zinc finger APH PF01636.23 KFH45844.1 - 8.1e-08 32.5 2.0 4.9e-05 23.4 0.8 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFH45844.1 - 4e-07 29.6 0.0 0.00045 19.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFH45844.1 - 5.7e-07 29.2 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KFH45844.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KFH45844.1 - 0.067 12.5 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH45844.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S10 PF00450.22 KFH45845.1 - 7.5e-115 384.7 0.0 9.5e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KFH45845.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chitin_synth_1 PF01644.17 KFH45846.1 - 7e-68 227.7 0.0 1e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFH45846.1 - 2.5e-27 94.6 0.0 4.5e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFH45846.1 - 2.7e-27 95.6 0.0 2.4e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFH45846.1 - 7e-09 35.9 0.1 7e-09 35.9 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFH45846.1 - 0.00044 20.2 0.0 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GCP_C_terminal PF04130.13 KFH45847.1 - 7e-100 334.5 0.0 1.2e-99 333.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFH45847.1 - 1.3e-81 274.6 0.0 2.3e-81 273.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal UQ_con PF00179.26 KFH45848.1 - 4.7e-36 123.5 0.0 6.7e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lipase_GDSL_2 PF13472.6 KFH45849.1 - 1e-23 84.7 0.0 1.3e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH45849.1 - 1e-14 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFH45849.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CDT1_C PF16679.5 KFH45851.1 - 9.5e-24 83.7 0.1 9.5e-24 83.7 0.1 3.1 4 0 0 4 4 4 1 DNA replication factor Cdt1 C-terminal domain Yippee-Mis18 PF03226.14 KFH45852.1 - 5.8e-20 71.5 0.0 8.4e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFH45852.1 - 0.016 15.4 0.4 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I PALP PF00291.25 KFH45853.1 - 6.3e-60 203.1 4.5 1.5e-59 201.8 4.5 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HRDC PF00570.23 KFH45853.1 - 0.034 14.1 0.0 6.6 6.8 0.0 3.3 3 1 0 3 3 3 0 HRDC domain DUF3343 PF11823.8 KFH45853.1 - 0.16 11.4 0.6 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) SAICAR_synt PF01259.18 KFH45854.1 - 2.7e-91 305.7 0.0 3.2e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Aldo_ket_red PF00248.21 KFH45855.1 - 7.3e-09 35.2 0.0 1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KFH45856.1 - 3.1e-44 151.3 30.1 3.1e-44 151.3 30.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45856.1 - 2.4e-08 33.3 9.6 2.4e-08 33.3 9.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFH45856.1 - 0.084 11.2 2.2 0.18 10.1 2.2 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3405 PF11885.8 KFH45857.1 - 1.2e-199 664.2 1.8 1.9e-198 660.3 1.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Sdh5 PF03937.16 KFH45858.1 - 1.3e-24 85.9 0.1 4e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase cNMP_binding PF00027.29 KFH45859.1 - 2.6e-39 133.2 0.0 9.2e-20 70.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4846 PF16138.5 KFH45859.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (4846) Pkinase PF00069.25 KFH45860.1 - 3e-74 249.7 0.0 4.6e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45860.1 - 1.4e-37 129.4 0.0 2.4e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFH45860.1 - 1.3e-19 70.8 0.1 2.8e-11 43.9 0.0 3.2 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KFH45860.1 - 1.2e-14 54.1 0.2 2.3e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KFH45860.1 - 1.6e-06 27.7 0.0 3.4e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like SUIM_assoc PF16619.5 KFH45860.1 - 9e-05 22.5 5.6 0.00025 21.0 5.0 2.0 2 0 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 RIO1 PF01163.22 KFH45860.1 - 0.00072 19.2 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFH45860.1 - 0.0011 18.0 0.7 0.0022 17.0 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KFH45860.1 - 0.0054 15.6 0.1 0.0091 14.9 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KFH45860.1 - 0.079 12.9 0.3 0.33 10.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FSA_C PF10479.9 KFH45860.1 - 0.29 9.2 3.9 0.51 8.4 3.9 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 KFH45860.1 - 0.34 11.1 9.3 0.06 13.6 3.4 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Roughex PF06020.11 KFH45860.1 - 0.57 9.2 6.8 0.95 8.5 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3439 PF11921.8 KFH45860.1 - 0.64 10.0 15.3 0.6 10.1 13.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4834 PF16118.5 KFH45860.1 - 6.2 7.9 9.7 82 4.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SSP160 PF06933.11 KFH45860.1 - 9 4.4 19.4 15 3.6 19.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Opy2 PF09463.10 KFH45861.1 - 1.1e-06 28.9 18.9 1.6e-06 28.3 18.9 1.3 1 0 0 1 1 1 1 Opy2 protein Trehalase PF01204.18 KFH45862.1 - 2.8e-189 630.2 0.0 3.3e-189 630.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KFH45862.1 - 2.8e-16 58.9 0.5 4.5e-16 58.3 0.5 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain HAD_2 PF13419.6 KFH45863.1 - 6e-14 52.5 0.0 6.9e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH45863.1 - 5.3e-13 49.7 0.0 1.3e-08 35.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH45863.1 - 1.2e-07 31.7 0.2 2.7e-07 30.5 0.1 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KFH45863.1 - 1e-06 29.3 0.2 1.8e-05 25.2 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFH45863.1 - 0.016 14.8 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Acid_PPase PF12689.7 KFH45863.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase HD PF01966.22 KFH45864.1 - 3.3e-05 24.1 0.7 5.9e-05 23.3 0.3 1.7 2 0 0 2 2 2 1 HD domain DNA_pol_E_B PF04042.16 KFH45865.1 - 2.4e-63 213.3 0.0 3.5e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PGC7_Stella PF15549.6 KFH45865.1 - 0.0086 16.1 3.4 0.72 9.8 0.2 2.3 2 0 0 2 2 2 2 PGC7/Stella/Dppa3 domain RFamide_26RFa PF11109.8 KFH45865.1 - 0.056 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Fungal_TACC PF12709.7 KFH45867.1 - 1.4e-12 47.9 25.6 3.3e-12 46.7 1.8 4.5 4 1 0 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 KFH45867.1 - 0.00072 19.8 7.1 0.12 12.7 0.1 3.6 3 0 0 3 3 3 2 TSC-22/dip/bun family Shugoshin_N PF07558.11 KFH45867.1 - 0.026 14.4 4.5 0.076 12.9 0.4 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.8 KFH45867.1 - 0.06 13.4 37.1 0.51 10.4 1.4 4.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 KFH45867.1 - 0.11 12.4 4.4 8.2 6.4 0.1 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TACC_C PF05010.14 KFH45867.1 - 0.14 12.0 36.7 2.3 7.9 4.8 3.3 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LPP PF04728.13 KFH45867.1 - 0.18 12.2 5.0 2.8 8.4 0.1 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 KFH45867.1 - 0.41 9.9 25.1 0.96 8.7 7.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KFH45867.1 - 0.51 10.0 26.0 1.3 8.7 5.5 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) DUF2605 PF10792.9 KFH45867.1 - 1.2 9.2 3.9 1.7 8.6 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) DUF745 PF05335.13 KFH45867.1 - 3.4 7.3 27.0 0.022 14.5 13.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF745) SKA1 PF07160.12 KFH45867.1 - 3.5 7.4 29.5 0.41 10.5 5.1 3.4 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 FACT-Spt16_Nlob PF14826.6 KFH45868.1 - 5e-55 185.7 0.3 1.9e-54 183.8 0.3 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KFH45868.1 - 5.2e-54 182.5 0.1 5.2e-54 182.5 0.1 2.9 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KFH45868.1 - 6.2e-23 81.6 0.0 1.2e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFH45868.1 - 1.2e-15 57.7 1.2 2.5e-15 56.7 0.2 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like AMP-binding PF00501.28 KFH45870.1 - 2.8e-74 250.2 0.0 3.5e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFH45870.1 - 2.5e-20 72.1 0.2 5.5e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KFH45870.1 - 1.7e-16 61.0 0.0 4.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Stn1_C PF12659.7 KFH45870.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Transthyretin PF00576.21 KFH45871.1 - 1.7e-35 122.1 0.0 2.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRA PF11786.8 KFH45872.1 - 1.7e-23 82.8 8.4 1.7e-23 82.8 8.4 3.7 2 2 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 KFH45872.1 - 9.9e-21 74.7 29.5 1e-13 52.2 3.2 5.4 4 3 1 5 5 5 2 Aft1 HRR domain Aft1_OSA PF11785.8 KFH45872.1 - 5e-16 58.9 27.3 2.6e-15 56.6 11.6 6.3 5 2 1 6 6 6 2 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KFH45872.1 - 9.7e-13 48.0 6.4 2.1e-12 47.0 6.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFH45872.1 - 9.2e-05 22.4 6.4 9.2e-05 22.4 6.4 2.9 3 0 0 3 3 3 1 Basic region leucine zipper DUF2722 PF10846.8 KFH45872.1 - 0.0025 16.8 10.8 0.0025 16.8 10.8 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) bZIP_Maf PF03131.17 KFH45872.1 - 0.0026 18.2 3.0 0.0026 18.2 3.0 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor HABP4_PAI-RBP1 PF04774.15 KFH45873.1 - 0.0011 19.8 0.2 0.0017 19.2 0.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RNA_Me_trans PF04252.13 KFH45874.1 - 1.8e-83 279.1 0.0 2e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DWNN PF08783.11 KFH45875.1 - 1.7e-30 105.1 0.1 2.9e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KFH45875.1 - 2.2e-09 36.9 7.0 8.2e-09 35.1 6.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KFH45875.1 - 0.00014 21.8 1.5 0.00027 20.9 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KFH45875.1 - 0.0011 19.1 0.1 0.0035 17.5 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-C3HC4_2 PF13923.6 KFH45875.1 - 0.0029 17.4 8.9 0.0029 17.4 8.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KFH45875.1 - 0.012 15.6 0.4 0.046 13.7 0.4 2.0 1 0 0 1 1 1 0 Zinc knuckle FYVE_2 PF02318.16 KFH45875.1 - 0.025 14.8 1.5 0.025 14.8 1.5 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.6 KFH45875.1 - 0.033 14.0 5.8 0.075 12.8 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFH45875.1 - 0.16 11.8 1.9 0.31 10.9 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KFH45875.1 - 0.36 10.7 5.5 0.81 9.5 4.6 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KFH45875.1 - 0.41 10.6 8.6 0.89 9.5 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH45875.1 - 0.77 9.8 13.4 0.072 13.1 7.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFH45875.1 - 1.2 9.4 7.9 4.1 7.6 7.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFH45875.1 - 1.6 9.1 13.9 0.032 14.6 7.2 1.6 2 0 0 2 2 1 0 Ring finger domain Cys_rich_VLP PF14194.6 KFH45876.1 - 2.2 8.4 7.0 0.83 9.8 2.1 2.1 1 1 2 3 3 3 0 Cysteine-rich VLP DLH PF01738.18 KFH45877.1 - 1.2e-19 70.8 0.5 3.6e-18 65.9 0.5 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.25 KFH45878.1 - 9.7e-52 175.9 0.0 9.7e-52 175.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45878.1 - 7.4e-20 71.3 0.0 1.8e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH45878.1 - 0.02 14.8 0.0 0.02 14.8 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family eIF-3_zeta PF05091.12 KFH45878.1 - 0.49 9.3 8.7 0.81 8.6 8.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 KFH45878.1 - 1.5 8.2 6.4 2.7 7.4 6.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Roughex PF06020.11 KFH45878.1 - 4.8 6.2 14.3 0.6 9.1 10.0 1.6 2 0 0 2 2 2 0 Drosophila roughex protein DUF4834 PF16118.5 KFH45878.1 - 9.2 7.3 12.1 57 4.8 12.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 KFH45879.1 - 8.2e-47 159.8 40.0 5.6e-42 143.9 24.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45879.1 - 1.8e-10 40.3 3.2 1.8e-10 40.3 3.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KFH45879.1 - 2.1e-06 27.3 6.6 2.1e-06 27.3 6.6 3.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4381 PF14316.6 KFH45879.1 - 0.2 11.9 2.4 1.3 9.3 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MFS_2 PF13347.6 KFH45879.1 - 0.34 9.4 23.6 0.0066 15.0 5.4 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein CDC45 PF02724.14 KFH45879.1 - 9.5 4.4 5.2 13 3.9 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldedh PF00171.22 KFH45880.1 - 4.8e-17 61.6 13.2 4.4e-10 38.7 10.2 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family zf-CCHC PF00098.23 KFH45882.1 - 2.9e-41 137.7 105.1 1e-06 28.6 1.4 12.1 12 0 0 12 12 12 11 Zinc knuckle zf-CCHC_4 PF14392.6 KFH45882.1 - 4.7e-08 32.6 59.9 0.17 11.6 1.0 10.2 9 1 1 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 KFH45882.1 - 0.0011 18.8 7.4 0.0022 17.8 1.3 11.6 12 0 0 12 12 12 7 Zinc knuckle zf-C2H2_10 PF16588.5 KFH45882.1 - 0.0027 17.4 1.6 0.0027 17.4 1.6 8.4 9 0 0 9 9 9 3 C2H2 zinc-finger zf-CCHC_3 PF13917.6 KFH45882.1 - 0.018 15.0 2.8 0.018 15.0 2.8 10.7 5 3 7 12 12 12 0 Zinc knuckle IlvN PF07991.12 KFH45884.1 - 3.9e-46 156.6 0.0 5.9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KFH45884.1 - 9.4e-41 139.5 0.1 1.3e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KFH45884.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MIS13 PF08202.11 KFH45885.1 - 1.7e-58 198.3 0.0 2.6e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FlaC_arch PF05377.11 KFH45885.1 - 0.13 12.7 1.1 4.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Trimer_CC PF08954.11 KFH45885.1 - 0.13 11.8 3.5 7.1 6.3 0.1 3.0 2 0 0 2 2 2 0 Trimerisation motif LPP PF04728.13 KFH45885.1 - 0.28 11.6 0.9 9.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 KFH45885.1 - 0.31 10.9 1.6 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.5 KFH45885.1 - 0.38 11.1 1.9 28 5.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Apolipoprotein PF01442.18 KFH45885.1 - 2.2 8.1 7.6 0.37 10.6 2.0 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SlyX PF04102.12 KFH45885.1 - 4.4 8.0 5.2 61 4.3 0.2 3.1 3 1 0 3 3 3 0 SlyX ZapB PF06005.12 KFH45885.1 - 7.5 7.1 11.1 1.3 9.5 1.5 3.0 2 1 1 3 3 3 0 Cell division protein ZapB BCAS2 PF05700.11 KFH45886.1 - 2.4e-56 190.7 3.4 2.7e-56 190.5 3.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 KFH45886.1 - 0.0052 17.0 1.5 0.0099 16.1 1.5 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding EMP24_GP25L PF01105.24 KFH45887.1 - 3.9e-40 137.7 0.0 4.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KFH45887.1 - 0.2 9.8 0.7 0.25 9.5 0.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SAGA-Tad1 PF12767.7 KFH45888.1 - 3.5e-53 180.8 0.0 4.5e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TTL PF03133.15 KFH45890.1 - 2.4e-55 187.7 0.0 3.5e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KFH45890.1 - 4.1e-53 180.1 0.0 6.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KFH45890.1 - 1.3e-05 24.5 0.0 7e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KFH45890.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ThiF PF00899.21 KFH45891.1 - 1.8e-39 135.6 0.0 2.8e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KFH45891.1 - 0.003 17.8 1.2 0.011 16.0 0.1 2.4 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.6 KFH45891.1 - 0.0031 17.9 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KFH45891.1 - 0.004 17.4 0.5 0.061 13.6 0.5 2.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KFH45891.1 - 0.0071 15.9 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFH45891.1 - 0.036 13.7 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 KFH45891.1 - 0.061 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.24 KFH45891.1 - 0.07 12.7 0.6 0.18 11.3 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH45891.1 - 0.086 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Coatomer_E PF04733.14 KFH45891.1 - 0.11 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Pyr_redox PF00070.27 KFH45891.1 - 0.16 12.6 0.2 0.41 11.2 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFH45891.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_2 PF08028.11 KFH45892.1 - 2.4e-13 50.5 0.2 4.6e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH45892.1 - 4.3e-06 27.4 0.0 7.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFH45892.1 - 0.00017 21.7 0.1 0.00053 20.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFH45892.1 - 0.0012 19.1 1.4 0.0072 16.5 0.1 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Gly_transf_sug PF04488.15 KFH45893.1 - 1.8e-14 54.1 0.0 4.1e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MAP17 PF15807.5 KFH45893.1 - 0.052 13.8 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 KFH45893.1 - 0.33 11.2 1.0 0.5 10.6 1.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Methyltransf_23 PF13489.6 KFH45894.1 - 3.4e-12 46.5 0.0 6.9e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH45894.1 - 6.1e-06 26.9 0.0 1.2e-05 25.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH45894.1 - 3e-05 24.6 0.0 8.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH45894.1 - 5.2e-05 23.9 0.0 0.00062 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH45894.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KFH45894.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KFH45894.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.5 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF938 PF06080.12 KFH45894.1 - 0.24 11.2 0.0 19 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KFH45894.1 - 0.24 11.2 0.0 0.45 10.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 KFH45895.1 - 9.1e-83 278.2 0.1 1.2e-82 277.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH45895.1 - 2.9e-12 47.4 1.4 7.2e-12 46.1 1.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CTP_synth_N PF06418.14 KFH45895.1 - 0.13 11.6 0.0 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 CTP synthase N-terminus TRAM_LAG1_CLN8 PF03798.16 KFH45896.1 - 1.2e-44 152.4 17.4 1.2e-44 152.4 17.4 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFH45896.1 - 1.6e-20 72.5 0.3 4.6e-20 71.0 0.3 1.9 1 0 0 1 1 1 1 TRAM1-like protein SIR2 PF02146.17 KFH45897.1 - 1.1e-56 191.5 0.0 1.7e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFH45897.1 - 0.00026 20.8 0.1 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KFH45897.1 - 0.00044 20.0 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) S4 PF01479.25 KFH45898.1 - 2.6e-13 49.4 0.0 7.5e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KFH45898.1 - 4.2e-08 34.0 1.9 9.3e-08 32.9 1.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain ddrB-ParB PF18763.1 KFH45898.1 - 0.17 12.0 0.9 0.39 10.8 0.9 1.5 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain GHMP_kinases_N PF00288.26 KFH45899.1 - 2.5e-09 37.2 0.1 4.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFH45899.1 - 1.5e-05 25.2 0.9 4.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Kelch_3 PF13415.6 KFH45900.1 - 2.3e-25 88.3 14.2 3.9e-07 30.2 0.1 8.4 8 2 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFH45900.1 - 7.2e-25 86.7 17.2 2.6e-09 36.9 0.1 8.1 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFH45900.1 - 3.8e-21 74.6 0.8 3.8e-08 33.3 0.0 5.3 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KFH45900.1 - 1.9e-17 62.6 3.7 1.5e-07 30.9 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KFH45900.1 - 4.4e-16 58.1 1.6 1.6e-07 31.0 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KFH45900.1 - 8.9e-13 47.9 4.9 0.00024 21.0 0.0 6.7 7 1 0 7 7 7 3 Kelch motif FAD_binding_4 PF01565.23 KFH45901.1 - 1.6e-12 47.3 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Septin PF00735.18 KFH45902.1 - 6.9e-104 347.1 0.0 1.2e-103 346.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFH45902.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH45902.1 - 0.0039 17.1 0.3 0.0039 17.1 0.3 2.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFH45902.1 - 0.014 15.5 4.8 2.4 8.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 KFH45902.1 - 0.025 14.1 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KFH45902.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFH45902.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 KFH45902.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EB1 PF03271.17 KFH45902.1 - 0.11 12.8 1.7 3.9 7.8 1.3 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif Roc PF08477.13 KFH45902.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFH45902.1 - 0.11 12.7 1.1 0.37 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Ribosomal_S17e PF00833.18 KFH45902.1 - 0.56 10.1 5.0 1.6 8.7 5.0 1.7 1 0 0 1 1 1 0 Ribosomal S17 AAA_23 PF13476.6 KFH45902.1 - 8.3 6.9 8.8 17 5.8 3.9 2.3 2 1 0 2 2 2 0 AAA domain PPR PF01535.20 KFH45903.1 - 1.2e-08 34.7 0.3 2.5 8.5 0.0 6.0 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 KFH45903.1 - 1.4e-07 31.6 0.1 0.37 11.0 0.0 6.2 5 1 2 7 7 7 3 PPR repeat family PPR_long PF17177.4 KFH45903.1 - 3.2e-05 23.4 0.2 0.051 12.9 0.0 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KFH45903.1 - 3.7e-05 23.7 0.0 0.82 9.8 0.0 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFH45903.1 - 0.033 13.9 0.0 6.8 6.5 0.0 2.8 2 0 0 2 2 2 0 PPR repeat RRM_1 PF00076.22 KFH45905.1 - 5.5e-16 58.2 0.0 7.9e-15 54.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH45905.1 - 0.0096 16.0 0.0 0.026 14.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif EamA PF00892.20 KFH45906.1 - 1.2e-12 48.1 25.8 1.8e-06 28.2 0.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KFH45906.1 - 0.0038 16.2 17.1 0.012 14.6 13.7 2.9 1 1 1 2 2 2 1 Ceramide synthase regulator MASE3 PF17159.4 KFH45906.1 - 0.012 15.3 1.4 0.012 15.3 1.4 2.3 3 0 0 3 3 3 0 Membrane-associated sensor domain Nuc_sug_transp PF04142.15 KFH45906.1 - 0.067 12.4 3.6 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Alpha-amylase PF00128.24 KFH45907.1 - 3.1e-111 372.2 0.0 4.6e-111 371.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFH45907.1 - 0.0066 15.6 0.1 0.014 14.5 0.0 1.5 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain CpxA_peri PF16527.5 KFH45907.1 - 0.047 14.1 0.0 8.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain TPR_16 PF13432.6 KFH45908.1 - 0.018 15.7 1.0 3.3 8.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFH45908.1 - 0.096 13.0 0.1 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFH45908.1 - 0.13 12.7 0.1 0.44 11.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Thioredox_DsbH PF03190.15 KFH45909.1 - 1e-56 191.4 0.0 1.8e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFH45909.1 - 2.6e-05 24.3 0.0 6.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like HTH_10 PF04967.12 KFH45909.1 - 0.075 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Histone_HNS PF00816.21 KFH45909.1 - 0.4 11.5 1.8 33 5.4 0.9 2.7 2 1 0 2 2 2 0 H-NS histone family Cerato-platanin PF07249.12 KFH45910.1 - 3.7e-51 172.2 1.0 4.3e-51 172.0 1.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Tubulin PF00091.25 KFH45911.1 - 1.1e-68 231.4 0.0 4e-68 229.5 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFH45911.1 - 5.9e-43 146.0 0.1 9e-43 145.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFH45911.1 - 1.8e-05 25.0 0.0 4.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFH45911.1 - 0.0041 16.8 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFH45911.1 - 0.0054 16.0 0.0 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin like Atg29_N PF18388.1 KFH45914.1 - 1.7e-26 91.8 2.1 2.8e-26 91.1 2.1 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Pmp3 PF01679.17 KFH45915.1 - 3.9e-24 84.6 7.7 4.3e-24 84.5 7.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MR_MLE_C PF13378.6 KFH45916.1 - 4.3e-58 196.5 0.2 6e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFH45916.1 - 1.9e-13 50.6 0.1 7.7e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Inositol_P PF00459.25 KFH45917.1 - 1.2e-51 175.8 1.3 2.1e-51 175.0 1.3 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Aminotran_4 PF01063.19 KFH45918.1 - 8.9e-34 117.3 0.0 1.2e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aim21 PF11489.8 KFH45919.1 - 1.2e-174 583.2 90.1 1.2e-174 583.2 90.1 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Cupin_2 PF07883.11 KFH45920.1 - 0.00013 21.6 1.3 0.24 11.2 0.0 3.6 4 0 0 4 4 4 2 Cupin domain Cupin_6 PF12852.7 KFH45920.1 - 0.0035 17.1 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.19 KFH45920.1 - 0.0045 16.9 0.1 5.9 6.8 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain PMI_typeI PF01238.21 KFH45920.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I Cupin_3 PF05899.12 KFH45920.1 - 0.046 13.4 0.1 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) JmjC PF02373.22 KFH45920.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase MFS_1 PF07690.16 KFH45921.1 - 2.3e-23 82.7 29.7 2.2e-21 76.2 25.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45921.1 - 8.9e-06 24.8 21.1 0.0026 16.7 4.5 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Chordopox_L2 PF05803.12 KFH45921.1 - 5 7.0 7.2 2.2 8.2 0.7 2.6 2 0 0 2 2 2 0 Chordopoxvirus L2 protein DHDPS PF00701.22 KFH45922.1 - 1.9e-33 115.4 0.0 2.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family COQ9 PF08511.11 KFH45922.1 - 0.023 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 COQ9 Acetyltransf_10 PF13673.7 KFH45923.1 - 2.6e-08 33.9 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH45923.1 - 3.5e-07 30.5 0.0 5.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH45923.1 - 1.2e-05 25.5 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFH45923.1 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KFH45923.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFH45923.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cg6151-P PF10233.9 KFH45924.1 - 1.3e-38 131.8 15.0 1.5e-38 131.6 15.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KFH45924.1 - 0.011 15.4 7.9 0.014 15.1 7.9 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 BAGE PF08180.11 KFH45924.1 - 0.11 12.6 2.5 0.22 11.6 2.5 1.6 1 0 0 1 1 1 0 B melanoma antigen family Holin_BlyA PF05102.12 KFH45924.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.2 2 1 0 2 2 2 0 holin, BlyA family CitMHS PF03600.16 KFH45924.1 - 0.33 10.1 11.0 0.38 9.9 11.0 1.1 1 0 0 1 1 1 0 Citrate transporter Cytochrom_B558a PF05038.13 KFH45924.1 - 2 8.0 5.6 3.8 7.0 5.5 1.6 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit RNase_H2-Ydr279 PF09468.10 KFH45925.1 - 3.3e-43 147.7 0.5 3.3e-43 147.7 0.5 2.1 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFH45925.1 - 5.5e-27 93.8 0.0 1.5e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain AcMNPV_Ac109 PF05054.12 KFH45925.1 - 0.025 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Casc1_N PF15927.5 KFH45925.1 - 0.17 11.6 8.6 0.45 10.2 8.6 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ADH_zinc_N PF00107.26 KFH45926.1 - 1.9e-08 34.4 0.0 3.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ceramidase_alk PF04734.13 KFH45926.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal SNF2_N PF00176.23 KFH45928.1 - 2.2e-47 161.5 0.1 3.8e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KFH45928.1 - 6.1e-28 96.7 1.1 2e-27 95.1 1.1 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KFH45928.1 - 1.2e-18 67.5 0.0 7.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFH45928.1 - 5.3e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFH45928.1 - 2e-06 27.9 0.0 2.2e-05 24.5 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH45928.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFH45928.1 - 0.0014 18.4 0.0 0.0061 16.2 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 KFH45928.1 - 0.038 12.9 0.5 1.4 7.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 2Fe-2S_thioredx PF01257.19 KFH45929.1 - 1.2e-59 200.4 0.0 1.5e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.28 KFH45930.1 - 1.1e-84 284.4 0.0 1.4e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH45930.1 - 2.4e-19 70.1 0.3 1.2e-18 67.8 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KFH45931.1 - 3.8e-18 65.5 0.0 8.2e-18 64.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45931.1 - 5.3 7.2 7.0 9.8 6.4 7.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_ATPase_C PF00689.21 KFH45932.1 - 1.2e-41 142.5 1.8 1.2e-41 142.5 1.8 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFH45932.1 - 7.9e-36 123.3 0.7 7.9e-36 123.3 0.7 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFH45932.1 - 2.4e-24 85.2 0.0 4.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH45932.1 - 3.2e-19 70.1 0.3 2.5e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH45932.1 - 8.7e-05 22.1 0.6 0.0016 18.1 0.0 2.8 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH45932.1 - 0.00017 21.4 0.2 0.00034 20.4 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFH45932.1 - 0.017 14.0 1.2 0.036 12.9 1.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DAGK_cat PF00781.24 KFH45932.1 - 0.13 11.9 0.0 0.62 9.7 0.0 2.0 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain RskA PF10099.9 KFH45932.1 - 0.47 10.7 6.0 3.6 7.8 0.2 4.0 3 1 1 4 4 4 0 Anti-sigma-K factor rskA Abhydrolase_3 PF07859.13 KFH45933.1 - 1.3e-52 178.7 0.1 8.1e-52 176.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH45933.1 - 1.6e-09 37.2 0.5 5.1e-09 35.5 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFH45933.1 - 0.00027 20.5 0.0 0.095 12.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family CorA PF01544.18 KFH45934.1 - 5.7e-05 22.6 0.2 0.00014 21.3 0.2 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Dna2 PF08696.11 KFH45935.1 - 8.2e-69 231.5 0.2 2.1e-68 230.2 0.0 1.8 2 0 0 2 2 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFH45935.1 - 6e-52 176.2 0.0 1.1e-51 175.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFH45935.1 - 4.7e-33 115.1 2.1 6.4e-16 58.9 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KFH45935.1 - 8.2e-17 61.6 0.0 1.8e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH45935.1 - 8.9e-13 48.8 0.0 3.1e-12 47.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 KFH45935.1 - 1e-10 42.0 0.1 1.5e-09 38.2 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KFH45935.1 - 7.8e-06 25.8 0.2 0.33 10.6 0.1 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KFH45935.1 - 0.00038 20.3 0.0 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KFH45935.1 - 0.00047 19.4 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 KFH45935.1 - 0.0013 19.2 0.0 0.0051 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain SRP54 PF00448.22 KFH45935.1 - 0.0013 18.4 0.2 0.0024 17.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KFH45935.1 - 0.0024 17.4 0.3 0.0098 15.4 0.2 2.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KFH45935.1 - 0.0081 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MobB PF03205.14 KFH45935.1 - 0.011 15.6 0.5 0.04 13.8 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 KFH45935.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KFH45935.1 - 0.015 14.8 0.1 0.037 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFH45935.1 - 0.017 14.7 0.1 0.16 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain Csa1 PF06023.12 KFH45935.1 - 0.046 13.1 0.3 0.25 10.6 0.0 2.2 2 1 0 2 2 2 0 CRISPR-associated exonuclease Csa1 AAA_33 PF13671.6 KFH45935.1 - 0.064 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFH45935.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KFH45935.1 - 0.074 13.1 0.1 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFH45935.1 - 0.076 12.9 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 KFH45935.1 - 0.092 12.0 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF365 PF04033.12 KFH45935.1 - 0.092 13.0 0.2 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF365) T2SSE PF00437.20 KFH45935.1 - 0.1 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KFH45935.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KFH45935.1 - 0.12 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KFH45935.1 - 0.14 11.5 0.1 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.9 KFH45935.1 - 0.31 9.9 1.3 0.35 9.7 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Bax1-I PF01027.20 KFH45936.1 - 4.9e-53 180.0 29.0 5.7e-53 179.8 29.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3824 PF12868.7 KFH45937.1 - 0.00036 21.2 8.8 0.00036 21.2 8.8 10.9 4 3 5 10 10 10 3 Domain of unknwon function (DUF3824) DUF533 PF04391.12 KFH45937.1 - 0.081 12.5 10.4 0.13 11.8 1.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF533) SfLAP PF11139.8 KFH45937.1 - 5.8 6.3 6.4 5 6.5 1.7 2.2 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein Ribosomal_S18 PF01084.20 KFH45938.1 - 5.1e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 ORC6 PF05460.13 KFH45938.1 - 0.0012 18.2 3.1 0.0015 17.9 3.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.32 KFH45940.1 - 0.00036 21.3 0.7 0.91 10.5 0.0 3.5 2 1 1 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH45940.1 - 0.0034 17.6 0.0 0.099 12.9 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KFH45940.1 - 0.0066 15.8 0.1 0.033 13.5 0.0 2.0 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Albumin_I PF08027.11 KFH45940.1 - 0.045 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Albumin I chain b IKI3 PF04762.12 KFH45940.1 - 0.058 11.4 0.0 0.076 11.0 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Lipase_3 PF01764.25 KFH45941.1 - 4.4e-33 114.1 0.0 6.1e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KFH45941.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 KFH45941.1 - 0.00029 21.5 0.1 0.00037 21.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH45941.1 - 0.00075 18.8 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFH45941.1 - 0.011 15.8 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KFH45941.1 - 0.021 14.4 0.2 0.038 13.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PE-PPE PF08237.11 KFH45941.1 - 0.032 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Aldo_ket_red PF00248.21 KFH45942.1 - 3.3e-48 164.4 0.0 4.4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DLIC PF05783.11 KFH45943.1 - 1.3e-30 106.7 0.0 5.5e-29 101.3 0.0 2.6 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) Pyridox_ox_2 PF12900.7 KFH45944.1 - 1.4e-35 122.3 0.0 2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KFH45945.1 - 1.7e-10 40.6 0.8 7.3e-08 32.2 0.1 3.0 2 1 0 2 2 2 2 F-box-like F-box PF00646.33 KFH45945.1 - 0.0021 17.9 4.0 0.27 11.1 0.3 3.1 3 0 0 3 3 3 2 F-box domain F-box_4 PF15966.5 KFH45945.1 - 0.034 14.0 0.2 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 F-box Stanniocalcin PF03298.13 KFH45946.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.3 1 1 0 1 1 1 1 Stanniocalcin family ABC_tran PF00005.27 KFH45947.1 - 7.4e-49 165.8 0.6 8.6e-23 81.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFH45947.1 - 2.1e-20 72.5 5.8 2.1e-20 72.5 5.8 3.9 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 KFH45947.1 - 1.1e-17 64.8 3.4 0.00029 20.8 0.0 4.6 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFH45947.1 - 1e-11 44.7 0.8 0.0036 16.8 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KFH45947.1 - 5e-06 27.1 0.2 0.17 12.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KFH45947.1 - 5e-06 26.6 1.2 0.054 13.6 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KFH45947.1 - 6.6e-06 25.8 0.2 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFH45947.1 - 2.1e-05 24.9 0.5 0.075 13.4 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KFH45947.1 - 2.8e-05 24.4 0.4 0.041 14.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KFH45947.1 - 4.8e-05 24.0 18.5 0.0052 17.3 0.1 4.8 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KFH45947.1 - 5.2e-05 23.0 0.3 0.0049 16.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KFH45947.1 - 7.5e-05 22.5 1.3 0.73 9.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFH45947.1 - 0.00011 22.5 0.4 0.47 10.7 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 KFH45947.1 - 0.00022 21.7 0.0 0.46 10.9 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFH45947.1 - 0.00024 21.1 1.7 0.27 11.1 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_33 PF13671.6 KFH45947.1 - 0.00024 21.3 0.1 1.1 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KFH45947.1 - 0.002 18.1 0.5 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KFH45947.1 - 0.0038 17.2 0.1 0.4 10.6 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 KFH45947.1 - 0.004 17.2 0.0 1.5 8.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KFH45947.1 - 0.0044 16.0 0.2 2.4 7.0 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KFH45947.1 - 0.0044 16.8 0.6 0.082 12.6 0.1 4.8 3 1 0 5 5 5 2 AAA ATPase domain RNA_helicase PF00910.22 KFH45947.1 - 0.0076 16.6 0.0 4.9 7.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.25 KFH45947.1 - 0.012 15.3 0.0 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KFH45947.1 - 0.014 14.9 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KFH45947.1 - 0.015 14.9 0.5 1.5 8.4 0.5 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KFH45947.1 - 0.017 14.3 0.0 4.6 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KFH45947.1 - 0.017 15.3 0.1 11 6.3 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KFH45947.1 - 0.019 14.9 1.2 5.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain TsaE PF02367.17 KFH45947.1 - 0.019 14.9 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KFH45947.1 - 0.023 14.6 0.3 0.57 10.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KFH45947.1 - 0.036 14.1 0.4 9.5 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KFH45947.1 - 0.05 13.7 9.3 3.4 7.7 0.0 4.0 3 1 0 3 3 3 0 Dynamin family TIP49 PF06068.13 KFH45947.1 - 0.06 12.6 0.9 0.55 9.4 0.0 2.7 4 0 0 4 4 2 0 TIP49 P-loop domain AAA_27 PF13514.6 KFH45947.1 - 0.13 11.8 6.7 5.6 6.5 0.0 4.0 5 0 0 5 5 5 0 AAA domain AAA_17 PF13207.6 KFH45947.1 - 1.4 9.4 6.2 29 5.1 0.2 3.9 4 0 0 4 4 3 0 AAA domain TPR_2 PF07719.17 KFH45948.1 - 4.2e-09 35.8 5.4 0.00021 21.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFH45948.1 - 2.3e-07 31.2 1.3 0.023 15.2 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH45948.1 - 2.7e-07 30.8 2.5 0.056 13.7 0.2 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFH45948.1 - 7.5e-07 28.7 0.6 0.0025 17.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFH45948.1 - 0.00038 20.6 2.1 15 6.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFH45948.1 - 0.00052 19.6 1.4 0.022 14.5 0.0 3.9 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 KFH45948.1 - 0.0045 16.9 2.0 7 6.9 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TAtT PF16811.5 KFH45948.1 - 0.0075 15.6 0.3 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 TRAP transporter T-component TPR_16 PF13432.6 KFH45948.1 - 0.012 16.2 0.2 0.012 16.2 0.2 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH45948.1 - 0.019 15.7 24.5 0.33 11.9 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFH45948.1 - 0.12 12.3 1.2 20 5.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFH45948.1 - 0.69 10.1 4.1 1.8 8.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ESSS PF10183.9 KFH45951.1 - 1.8e-09 37.7 0.1 2.2e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATG7_N PF16420.5 KFH45952.1 - 3.6e-106 355.2 0.0 4.5e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFH45952.1 - 1.2e-42 146.0 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family MTA_R1 PF17226.2 KFH45952.1 - 0.008 16.3 0.2 0.016 15.4 0.2 1.4 1 0 0 1 1 1 1 MTA R1 domain RAMA PF18755.1 KFH45952.1 - 0.15 12.5 0.0 6.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated Pkinase PF00069.25 KFH45953.1 - 3.3e-17 62.7 0.0 1.5e-16 60.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH45953.1 - 1.1e-09 37.9 0.0 1.2e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KFH45953.1 - 0.00048 19.9 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 EST1_DNA_bind PF10373.9 KFH45954.1 - 1.3e-09 37.9 0.2 5.7e-09 35.9 0.2 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Ribosomal_L6 PF00347.23 KFH45956.1 - 8.3e-21 74.5 0.0 5.6e-09 36.6 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 Cu_amine_oxid PF01179.20 KFH45957.1 - 1.8e-149 498.1 0.0 2.2e-149 497.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KFH45957.1 - 6.8e-05 23.0 0.1 0.00017 21.7 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KFH45957.1 - 0.00031 21.1 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain FUSC_2 PF13515.6 KFH45958.1 - 1.5e-14 54.2 38.7 8.2e-12 45.3 9.6 3.5 2 2 1 3 3 3 3 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KFH45958.1 - 8.1e-09 35.0 3.2 8.1e-09 35.0 3.2 3.2 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal DUF1097 PF06496.11 KFH45958.1 - 0.00014 22.0 31.9 0.0072 16.4 14.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1097) ALMT PF11744.8 KFH45958.1 - 0.0027 16.6 8.4 0.0027 16.6 8.4 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter ECF_trnsprt PF12822.7 KFH45958.1 - 0.99 9.5 23.3 0.19 11.8 11.9 2.5 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Wzy_C PF04932.15 KFH45958.1 - 5.3 6.7 14.6 0.48 10.0 2.0 3.1 3 0 0 3 3 3 0 O-Antigen ligase Sugar_tr PF00083.24 KFH45959.1 - 7.1e-82 275.7 23.1 8.8e-82 275.3 23.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45959.1 - 2.2e-16 59.8 48.7 7.9e-16 57.9 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-F PF06699.11 KFH45960.1 - 5e-64 215.8 1.9 7e-64 215.3 1.9 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4396 PF14342.6 KFH45960.1 - 0.2 12.0 2.2 0.71 10.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) zf-primase PF09329.11 KFH45961.1 - 3.6e-19 68.3 0.7 7e-19 67.4 0.7 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KFH45961.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Bac_luciferase PF00296.20 KFH45962.1 - 1.3e-60 205.5 0.2 1.6e-60 205.1 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DASH_Duo1 PF08651.10 KFH45963.1 - 9e-29 99.1 0.1 1.4e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DinB PF05163.12 KFH45963.1 - 0.028 14.3 0.5 0.039 13.9 0.5 1.3 1 0 0 1 1 1 0 DinB family SART-1 PF03343.13 KFH45963.1 - 0.032 12.8 6.5 0.043 12.4 6.5 1.1 1 0 0 1 1 1 0 SART-1 family DUF1682 PF07946.14 KFH45963.1 - 0.063 12.5 5.0 0.08 12.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.6 KFH45963.1 - 0.099 12.0 1.4 0.12 11.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spermine_synth PF01564.17 KFH45964.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KFH45964.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S26e PF01283.19 KFH45965.1 - 1.8e-52 176.3 9.6 2.1e-52 176.1 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KFH45965.1 - 0.02 14.8 0.4 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KFH45965.1 - 0.12 12.1 1.6 0.14 12.0 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) GFA PF04828.14 KFH45967.1 - 1.9e-07 31.4 7.9 0.00041 20.6 0.1 3.1 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KFH45967.1 - 0.00023 21.2 0.7 0.43 10.8 0.1 2.9 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Ogr_Delta PF04606.12 KFH45967.1 - 6.3 6.9 9.7 0.78 9.8 1.4 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Methyltransf_2 PF00891.18 KFH45968.1 - 4.6e-22 78.3 0.0 7.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KFH45968.1 - 0.058 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFH45968.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cu_amine_oxid PF01179.20 KFH45969.1 - 2.6e-158 527.2 0.0 3.2e-158 526.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KFH45969.1 - 5e-09 36.3 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KFH45969.1 - 0.036 14.5 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain Glyco_hydro_2_C PF02836.17 KFH45971.1 - 4.2e-101 338.0 0.2 5.9e-101 337.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFH45971.1 - 4.1e-64 216.5 0.1 7.3e-64 215.7 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFH45971.1 - 5.4e-43 146.8 0.2 1.2e-42 145.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFH45971.1 - 4.5e-21 75.1 0.1 1.7e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFH45971.1 - 3.2e-10 40.6 0.4 1.1e-09 38.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.15 KFH45971.1 - 0.025 13.9 0.8 0.041 13.2 0.2 1.5 2 0 0 2 2 2 0 Beta-galactosidase Mpv17_PMP22 PF04117.12 KFH45972.1 - 4.2e-14 52.5 0.7 4.2e-14 52.5 0.7 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.16 KFH45973.1 - 1.1e-28 100.2 20.7 2.5e-28 99.0 20.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45973.1 - 7e-06 25.2 17.2 0.0001 21.3 16.1 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2627 PF11118.8 KFH45973.1 - 2.1 9.0 6.7 2.6 8.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) PolyA_pol_RNAbd PF12627.7 KFH45974.1 - 0.0002 21.0 0.1 0.029 14.1 0.0 2.2 2 0 0 2 2 2 2 Probable RNA and SrmB- binding site of polymerase A Cytomega_UL84 PF06284.11 KFH45975.1 - 0.69 8.3 5.2 0.75 8.2 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ribosomal_60s PF00428.19 KFH45975.1 - 8.4 7.1 14.0 14 6.3 14.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BATS PF06968.13 KFH45976.1 - 5.7e-23 80.9 0.0 1.9e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KFH45976.1 - 7.4e-16 59.0 0.2 3.5e-15 56.8 0.1 2.1 3 0 0 3 3 3 1 Radical SAM superfamily TPR_10 PF13374.6 KFH45976.1 - 0.25 11.2 1.0 0.76 9.7 1.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_N_2 PF16884.5 KFH45977.1 - 1.1e-27 96.0 0.0 2.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFH45977.1 - 1.2e-19 70.6 0.1 2e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH45977.1 - 2.2e-06 28.8 0.0 4.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_S10 PF00338.22 KFH45978.1 - 1.5e-26 92.5 0.3 1.8e-26 92.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 KFH45978.1 - 0.013 14.2 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein SLS PF14611.6 KFH45978.1 - 0.1 12.4 0.4 1.5 8.6 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator AAA PF00004.29 KFH45979.1 - 6.2e-42 143.2 0.0 1.6e-41 141.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFH45979.1 - 2.4e-27 94.7 0.8 9.2e-27 92.8 0.3 2.3 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KFH45979.1 - 4.9e-17 61.8 5.7 1.8e-16 59.9 5.7 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KFH45979.1 - 2.9e-07 30.2 0.0 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 KFH45979.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFH45979.1 - 6e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KFH45979.1 - 1.7e-05 25.2 0.1 0.0022 18.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFH45979.1 - 3.5e-05 23.8 0.0 0.00021 21.3 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH45979.1 - 3.8e-05 24.0 0.1 0.0079 16.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFH45979.1 - 4.6e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFH45979.1 - 4.8e-05 23.7 0.0 0.0098 16.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KFH45979.1 - 5e-05 23.3 0.0 0.00022 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KFH45979.1 - 0.00033 19.9 0.1 0.0017 17.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFH45979.1 - 0.00083 19.9 0.1 0.0034 17.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFH45979.1 - 0.00084 19.1 1.4 0.0054 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain PrkA PF06798.12 KFH45979.1 - 0.0017 18.1 1.2 0.0089 15.7 1.1 2.0 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_33 PF13671.6 KFH45979.1 - 0.0023 18.1 0.0 0.0083 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFH45979.1 - 0.0025 17.9 0.0 0.0086 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KFH45979.1 - 0.011 15.2 0.2 0.093 12.2 0.0 2.6 3 1 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFH45979.1 - 0.012 15.2 0.1 0.33 10.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 KFH45979.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFH45979.1 - 0.026 13.9 0.0 0.08 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TPR_12 PF13424.6 KFH45979.1 - 0.041 14.2 0.8 0.083 13.2 0.3 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat PhoH PF02562.16 KFH45979.1 - 0.055 12.9 0.4 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein NRDE-2 PF08424.10 KFH45979.1 - 0.06 12.5 0.4 0.095 11.8 0.4 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference NACHT PF05729.12 KFH45979.1 - 0.09 12.7 0.0 0.71 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KFH45979.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 KFH45979.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.6 KFH45979.1 - 0.11 12.3 0.1 13 5.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 KFH45979.1 - 0.13 11.9 0.2 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase MAPEG PF01124.18 KFH45980.1 - 3.2e-11 43.2 2.6 4.3e-11 42.8 2.6 1.3 1 1 0 1 1 1 1 MAPEG family Na_H_Exchanger PF00999.21 KFH45981.1 - 5.8e-40 137.3 10.3 1.1e-39 136.3 10.3 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KFH45981.1 - 0.01 15.9 0.1 0.01 15.9 0.1 3.0 4 0 0 4 4 4 1 YrhC-like protein YwcE PF17368.2 KFH45981.1 - 0.21 12.3 2.6 0.27 11.9 0.6 2.3 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE Phage_lysozyme PF00959.19 KFH45982.1 - 2.5e-05 24.7 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Prefoldin_2 PF01920.20 KFH45983.1 - 5.3e-19 68.1 10.0 1.3e-14 54.0 2.2 2.0 2 0 0 2 2 2 2 Prefoldin subunit DUF5082 PF16888.5 KFH45983.1 - 0.00049 20.4 5.0 0.0064 16.8 1.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) PHM7_cyt PF14703.6 KFH45983.1 - 0.00065 20.0 1.4 0.0012 19.1 1.4 1.4 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Fez1 PF06818.15 KFH45983.1 - 0.00093 19.7 4.8 0.0024 18.4 0.8 2.1 2 0 0 2 2 2 1 Fez1 COG5 PF10392.9 KFH45983.1 - 0.0037 17.4 0.4 0.092 12.9 0.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Prefoldin PF02996.17 KFH45983.1 - 0.0041 17.0 5.3 0.012 15.5 1.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Rx_N PF18052.1 KFH45983.1 - 0.014 15.6 3.8 0.26 11.6 0.2 2.4 2 1 0 2 2 2 0 Rx N-terminal domain GAS PF13851.6 KFH45983.1 - 0.017 14.5 5.7 0.84 8.9 0.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MIP-T3_C PF17749.1 KFH45983.1 - 0.021 14.8 5.4 0.029 14.3 2.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region KxDL PF10241.9 KFH45983.1 - 0.028 14.7 2.3 27 5.1 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein Prefoldin_3 PF13758.6 KFH45983.1 - 0.036 14.1 1.0 0.15 12.2 1.0 2.1 1 1 0 1 1 1 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KFH45983.1 - 0.037 14.3 8.2 0.8 10.0 3.5 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 KFH45983.1 - 0.044 13.6 10.6 1.8 8.4 1.2 3.2 3 0 0 3 3 3 0 Septum formation initiator Siah-Interact_N PF09032.11 KFH45983.1 - 0.046 14.0 5.3 1.9 8.8 0.5 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal ADIP PF11559.8 KFH45983.1 - 0.055 13.5 3.6 0.25 11.4 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GLE1 PF07817.13 KFH45983.1 - 0.11 11.6 2.9 0.12 11.6 0.6 1.8 1 1 1 2 2 2 0 GLE1-like protein Com_YlbF PF06133.11 KFH45983.1 - 0.12 13.0 6.5 1.5 9.4 0.2 2.4 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Wtap PF17098.5 KFH45983.1 - 0.12 12.2 4.0 0.46 10.4 4.0 1.9 1 1 0 1 1 1 0 WTAP/Mum2p family UPF0242 PF06785.11 KFH45983.1 - 0.13 12.4 7.3 2.2 8.3 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 KFH45983.1 - 0.15 12.2 7.7 0.59 10.2 0.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc24 PF08286.11 KFH45983.1 - 0.17 12.2 5.1 2.2 8.6 0.3 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Tup_N PF08581.10 KFH45983.1 - 0.18 12.1 7.1 14 6.1 1.4 3.1 3 0 0 3 3 3 0 Tup N-terminal DUF4164 PF13747.6 KFH45983.1 - 0.2 12.0 3.7 5.1 7.5 0.2 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) Atg14 PF10186.9 KFH45983.1 - 0.24 10.4 3.4 0.9 8.6 0.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KFH45983.1 - 0.28 11.6 4.0 2.7 8.4 0.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KFH45983.1 - 0.29 10.0 9.6 2 7.2 9.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein SKA2 PF16740.5 KFH45983.1 - 0.4 10.5 7.6 0.25 11.1 0.8 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TolA_bind_tri PF16331.5 KFH45983.1 - 0.43 10.7 7.0 0.84 9.8 0.3 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 KFH45983.1 - 0.58 10.6 4.3 4.5 7.8 0.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.8 KFH45983.1 - 0.61 10.5 9.4 0.89 9.9 0.7 2.3 2 1 0 2 2 2 0 YlqD protein LPP PF04728.13 KFH45983.1 - 0.77 10.2 7.7 2.3 8.7 0.5 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DHR10 PF18595.1 KFH45983.1 - 0.79 9.8 8.9 4.9 7.2 1.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 KFH45983.1 - 0.85 7.5 3.6 0.56 8.1 0.5 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 KFH45983.1 - 1 8.9 6.6 13 5.3 6.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Cep57_MT_bd PF06657.13 KFH45983.1 - 1.3 9.5 7.1 12 6.4 0.5 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.6 KFH45983.1 - 3.5 8.1 6.3 19 5.8 0.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAD_binding_3 PF01494.19 KFH45984.1 - 7e-17 61.7 0.3 9e-10 38.3 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH45984.1 - 0.00062 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH45984.1 - 0.0015 18.2 0.1 0.0037 16.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 KFH45984.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KFH45984.1 - 0.026 15.1 0.0 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFH45984.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFH45984.1 - 0.16 11.2 0.1 0.39 9.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KFH45985.1 - 3.1e-15 56.0 7.7 3.4e-15 55.9 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45985.1 - 0.088 11.7 4.2 0.14 11.1 4.2 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily GWT1 PF06423.12 KFH45985.1 - 0.16 12.1 2.1 0.094 12.8 0.3 1.6 2 0 0 2 2 2 0 GWT1 DUF1129 PF06570.11 KFH45985.1 - 0.17 11.3 2.7 0.23 10.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) An_peroxidase PF03098.15 KFH45986.1 - 5.2e-43 147.4 0.0 7.5e-31 107.3 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KFH45986.1 - 4.3e-06 25.8 0.1 7.6e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 TRI12 PF06609.13 KFH45987.1 - 3.7e-59 200.7 21.2 5e-59 200.3 21.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH45987.1 - 8.8e-20 70.9 55.5 5.6e-19 68.3 50.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Fig1 PF12351.8 KFH45988.1 - 1.9e-58 197.5 3.8 1.9e-58 197.5 3.8 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KFH45988.1 - 1.3e-08 34.8 8.1 1.9e-08 34.2 8.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KFH45988.1 - 0.0014 17.7 10.7 0.0043 16.2 10.7 1.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF1993 PF09351.10 KFH45989.1 - 1.7e-45 155.1 0.0 1.9e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) JAB PF01398.21 KFH45990.1 - 2.4e-13 50.1 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KFH45990.1 - 5.9e-07 29.7 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KFH45990.1 - 2.7e-05 23.9 0.0 7.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Zn_clus PF00172.18 KFH45991.1 - 0.01 15.9 10.3 0.016 15.3 10.3 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH45991.1 - 0.037 13.1 0.1 3.4 6.6 0.2 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain FUSC_2 PF13515.6 KFH45991.1 - 0.12 12.5 0.6 0.25 11.5 0.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Mito_carr PF00153.27 KFH45992.1 - 1.6e-53 178.6 2.7 2.5e-20 72.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KFH45994.1 - 5e-12 45.4 0.1 9.3e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH45994.1 - 4.7e-07 29.8 8.8 1e-06 28.7 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KFH45994.1 - 0.013 15.3 0.9 0.032 14.1 0.9 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2039 PF10217.9 KFH45994.1 - 0.62 10.4 5.5 1.2 9.5 5.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) MFS_1 PF07690.16 KFH45995.1 - 5.1e-37 127.6 35.8 5.1e-37 127.6 35.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH45996.1 - 2.5e-34 119.0 5.7 3.4e-34 118.5 5.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH45996.1 - 2.6e-17 62.8 14.9 3.4e-17 62.4 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH45996.1 - 0.00035 19.1 3.5 0.00048 18.7 3.1 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 KFH45997.1 - 4.2e-13 49.2 0.0 2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH45997.1 - 1.6e-06 27.9 0.0 7.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Glyoxalase PF00903.25 KFH45998.1 - 4.3e-07 30.2 0.0 5.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFH45998.1 - 0.014 16.1 0.0 0.021 15.6 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain MFS_1 PF07690.16 KFH45999.1 - 1.5e-10 40.5 36.5 3e-10 39.6 36.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFH45999.1 - 4.5e-08 32.9 5.9 4.5e-08 32.9 5.9 2.7 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 EXS PF03124.14 KFH45999.1 - 0.0054 16.1 1.4 0.014 14.7 1.4 1.7 1 0 0 1 1 1 1 EXS family LapA_dom PF06305.11 KFH45999.1 - 0.05 13.4 0.0 0.05 13.4 0.0 3.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Cupin_7 PF12973.7 KFH46000.1 - 0.072 13.0 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain zf-FPG_IleRS PF06827.14 KFH46001.1 - 0.0019 18.0 1.3 0.0041 16.9 1.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS SMC_N PF02463.19 KFH46002.1 - 4.5e-67 225.7 39.1 1.6e-66 223.9 39.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFH46002.1 - 1e-25 90.3 0.0 3.7e-25 88.5 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFH46002.1 - 9.5e-13 48.6 2.9 3.3e-05 23.8 0.9 3.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH46002.1 - 0.00066 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KFH46002.1 - 0.0023 18.1 14.3 0.0023 18.1 14.3 7.6 4 2 5 9 9 9 1 Tropomyosin like LPP PF04728.13 KFH46002.1 - 0.14 12.6 0.1 0.14 12.6 0.1 8.8 6 2 1 8 8 8 0 Lipoprotein leucine-zipper ABC_tran PF00005.27 KFH46002.1 - 0.94 10.0 0.0 0.94 10.0 0.0 6.3 4 2 1 5 5 5 0 ABC transporter Spc7 PF08317.11 KFH46002.1 - 2.9 6.7 134.2 0.067 12.1 22.7 7.1 3 2 4 7 7 7 0 Spc7 kinetochore protein Alpha-amylase PF00128.24 KFH46003.1 - 5.1e-112 374.8 0.0 7.3e-112 374.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFH46003.1 - 0.007 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFH46003.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_114 PF03537.13 KFH46003.1 - 0.087 12.1 0.1 0.53 9.5 0.1 2.1 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 DUF4434 PF14488.6 KFH46003.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF2204 PF09970.9 KFH46004.1 - 0.058 13.0 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Glyco_hydro81C PF17652.1 KFH46005.1 - 3e-92 309.5 1.9 3.4e-92 309.4 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Abhydrolase_3 PF07859.13 KFH46006.1 - 2.9e-53 180.9 0.2 3.8e-53 180.5 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH46006.1 - 9.2e-05 21.5 0.2 0.00034 19.6 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KFH46006.1 - 0.00011 22.9 6.3 0.00016 22.4 6.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KFH46006.1 - 0.012 14.4 0.1 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KFH46006.1 - 0.18 11.3 1.3 1.7 8.1 0.0 2.3 1 1 1 2 2 2 0 Esterase PHB depolymerase APH PF01636.23 KFH46007.1 - 4.5e-16 59.5 0.0 1.9e-15 57.4 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family PrpR_N PF06506.11 KFH46007.1 - 0.077 12.6 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Propionate catabolism activator Haspin_kinase PF12330.8 KFH46007.1 - 0.2 10.6 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_18 PF00704.28 KFH46008.1 - 4.6e-84 282.8 0.2 5.3e-84 282.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KFH46008.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Inhibitor_I42 PF09394.10 KFH46008.1 - 0.16 12.4 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Sec34 PF04136.15 KFH46009.1 - 1.1e-50 171.4 2.0 4.4e-50 169.5 2.0 2.1 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 KFH46009.1 - 0.02 14.7 1.3 0.23 11.2 0.1 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 BST2 PF16716.5 KFH46009.1 - 4.5 7.9 6.2 1.4 9.6 1.0 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Epimerase PF01370.21 KFH46010.1 - 4.5e-21 75.4 0.0 1.1e-20 74.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH46010.1 - 6.7e-10 38.9 0.6 1.1e-09 38.2 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFH46010.1 - 2.5e-08 33.4 0.0 1.6e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFH46010.1 - 4.1e-08 33.3 0.2 9.8e-08 32.1 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFH46010.1 - 5.3e-08 32.2 0.0 1.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFH46010.1 - 3.5e-05 23.4 0.3 0.00015 21.3 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KFH46010.1 - 0.013 14.6 0.2 0.028 13.5 0.2 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KFH46010.1 - 0.027 14.0 0.1 0.066 12.8 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 KFH46010.1 - 0.035 13.7 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SEEK1 PF15357.6 KFH46010.1 - 0.062 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 KR PF08659.10 KFH46010.1 - 0.075 12.9 0.2 0.18 11.7 0.2 1.6 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KFH46010.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 KFH46011.1 - 3.6e-62 210.6 0.0 4.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KFH46011.1 - 0.14 11.9 0.6 0.61 9.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) ubiquitin PF00240.23 KFH46012.1 - 4.6e-34 116.0 0.6 7.8e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KFH46012.1 - 9.7e-25 86.5 0.9 9.7e-25 86.5 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KFH46012.1 - 2.8e-16 59.1 0.7 4.8e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFH46012.1 - 2.5e-05 24.6 0.1 0.00013 22.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFH46012.1 - 0.00075 19.6 0.7 0.0016 18.5 0.7 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFH46012.1 - 0.0045 17.3 0.9 0.0075 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFH46012.1 - 0.0055 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KFH46012.1 - 0.01 16.4 0.7 0.015 15.9 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KFH46012.1 - 0.02 14.9 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Amidase PF01425.21 KFH46014.1 - 9.1e-47 160.0 0.0 1.6e-43 149.3 0.0 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_125 PF06824.11 KFH46015.1 - 2.3e-15 56.4 0.0 6.6e-15 54.9 0.0 1.6 1 1 1 2 2 2 1 Metal-independent alpha-mannosidase (GH125) Fib_alpha PF08702.10 KFH46016.1 - 0.0092 16.2 12.7 2.4 8.3 0.0 4.6 3 2 2 5 5 5 1 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KFH46016.1 - 0.011 16.2 32.4 0.38 11.2 3.7 4.6 3 1 1 4 4 4 0 Fez1 Phage_GP20 PF06810.11 KFH46016.1 - 0.02 14.7 17.6 1.4 8.7 1.1 5.4 4 1 2 6 6 6 0 Phage minor structural protein GP20 TMPIT PF07851.13 KFH46016.1 - 0.046 13.0 10.2 1.8 7.7 0.8 3.7 3 1 1 4 4 4 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KFH46016.1 - 0.056 13.0 24.2 2.2 7.8 0.2 3.5 2 1 0 3 3 3 0 Exonuclease VII, large subunit Gp58 PF07902.11 KFH46016.1 - 0.082 11.2 6.2 0.85 7.8 0.5 2.6 2 0 0 2 2 2 0 gp58-like protein TMF_DNA_bd PF12329.8 KFH46016.1 - 0.1 12.6 28.3 0.2 11.7 0.0 6.4 5 2 2 7 7 6 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KFH46016.1 - 0.11 13.0 38.5 0.09 13.3 5.1 4.6 3 2 1 4 4 4 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KFH46016.1 - 0.13 12.5 23.6 1.1 9.6 4.6 5.0 4 1 0 4 4 4 0 ABC transporter C-terminal domain Spc7 PF08317.11 KFH46016.1 - 0.15 10.9 31.8 0.26 10.1 2.5 4.7 3 1 1 4 4 4 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 KFH46016.1 - 0.15 12.1 22.3 0.44 10.6 0.2 5.2 5 0 0 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_13 PF13166.6 KFH46016.1 - 0.17 10.5 19.4 0.27 9.8 8.7 3.7 2 1 1 3 3 3 0 AAA domain KASH_CCD PF14662.6 KFH46016.1 - 0.21 11.4 24.8 0.25 11.2 1.8 4.9 4 1 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KFH46016.1 - 0.28 11.2 18.0 1.5 8.9 0.1 5.6 4 2 1 6 6 6 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KFH46016.1 - 0.39 10.9 32.6 1.1 9.4 8.8 4.5 3 1 2 5 5 5 0 Tropomyosin like DUF641 PF04859.12 KFH46016.1 - 0.41 11.0 21.3 4.6 7.6 0.1 5.8 4 2 2 6 6 6 0 Plant protein of unknown function (DUF641) DUF4472 PF14739.6 KFH46016.1 - 0.47 11.2 21.0 1.3 9.8 0.7 4.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4472) OmpH PF03938.14 KFH46016.1 - 0.56 10.5 27.3 1.4 9.3 1.9 5.1 3 1 2 5 5 5 0 Outer membrane protein (OmpH-like) GAS PF13851.6 KFH46016.1 - 0.6 9.4 29.7 0.43 9.9 4.2 4.7 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 KFH46016.1 - 0.61 9.3 18.8 0.051 12.8 5.4 3.5 3 1 1 4 4 4 0 Monopolar spindle protein 2 BST2 PF16716.5 KFH46016.1 - 0.88 10.2 24.6 3.7 8.2 0.1 6.6 3 2 3 6 6 6 0 Bone marrow stromal antigen 2 Prefoldin PF02996.17 KFH46016.1 - 1.8 8.5 19.6 2.8 7.9 0.1 6.6 6 2 1 8 8 7 0 Prefoldin subunit YPEB PF14620.6 KFH46016.1 - 2.5 7.3 9.1 2.3 7.5 0.3 3.5 3 1 0 3 3 3 0 YpeB sporulation GCN5L1 PF06320.13 KFH46016.1 - 2.8 8.1 14.2 15 5.8 3.4 4.4 3 1 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) Nsp1_C PF05064.13 KFH46016.1 - 3.1 7.6 13.8 1.5 8.6 0.2 4.3 4 0 0 4 4 4 0 Nsp1-like C-terminal region GrpE PF01025.19 KFH46016.1 - 3.6 7.2 19.1 6.8 6.3 1.0 4.8 3 1 1 4 4 4 0 GrpE FlaC_arch PF05377.11 KFH46016.1 - 3.8 8.0 21.9 1.6 9.2 0.1 6.6 8 1 0 8 8 6 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 KFH46016.1 - 4.7 7.9 39.0 0.79 10.4 4.5 6.4 5 2 3 8 8 8 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KFH46016.1 - 5.4 7.1 28.5 8.8 6.4 0.2 5.1 3 2 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 KFH46016.1 - 7.1 7.6 36.1 0.82 10.6 3.3 5.6 3 2 2 5 5 5 0 cGMP-dependent protein kinase interacting domain CAP PF00188.26 KFH46018.1 - 4.6e-14 53.3 0.3 6.1e-14 52.9 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family YcaO_C PF18381.1 KFH46018.1 - 0.092 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain DUF5412 PF17428.2 KFH46018.1 - 0.16 11.8 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5412) MFS_1 PF07690.16 KFH46019.1 - 5e-30 104.6 24.0 5e-30 104.6 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP1_N PF08621.10 KFH46019.1 - 0.0072 16.1 0.3 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal MARVEL PF01284.23 KFH46021.1 - 5.8e-06 26.4 13.8 2.6e-05 24.3 13.8 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KFH46021.1 - 4.6 5.4 12.8 5.7 5.1 12.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_43 PF04616.14 KFH46022.1 - 6.4e-106 353.9 0.2 1e-105 353.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFH46022.1 - 7.5e-44 149.9 0.0 1.1e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 KFH46022.1 - 0.034 13.7 0.1 0.08 12.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain RCC1 PF00415.18 KFH46023.1 - 2.3e-26 92.2 4.2 8.8e-05 23.1 0.0 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFH46023.1 - 1.3e-13 50.3 18.9 3.3e-07 29.9 0.1 7.4 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 KFH46023.1 - 1.1 9.6 3.6 0.76 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) WSC PF01822.19 KFH46025.1 - 4.5e-10 39.6 5.8 4.5e-10 39.6 5.8 2.3 2 0 0 2 2 2 1 WSC domain Trypan_PARP PF05887.11 KFH46025.1 - 1.7e-05 24.8 49.8 1.7e-05 24.8 49.8 4.5 3 1 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) Peptidase_S8 PF00082.22 KFH46026.1 - 5.9e-30 104.6 8.0 1.1e-29 103.7 7.8 1.3 1 1 0 1 1 1 1 Subtilase family AlaDh_PNT_N PF05222.15 KFH46027.1 - 2.9e-19 69.7 0.0 5.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KFH46027.1 - 0.11 11.7 0.0 0.34 10.2 0.0 1.8 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 KFH46028.1 - 9.7e-28 96.9 1.6 1.6e-27 96.2 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arginase PF00491.21 KFH46029.1 - 3.3e-75 253.2 0.2 3.9e-75 252.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family Sugar_tr PF00083.24 KFH46030.1 - 4.8e-75 253.2 16.6 6.4e-75 252.7 16.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46030.1 - 4.9e-19 68.5 59.8 3.3e-12 46.0 23.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFH46030.1 - 7.6e-05 21.4 20.5 0.0071 15.0 0.9 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Folate_carrier PF01770.18 KFH46030.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Reduced folate carrier Mrx7 PF10906.8 KFH46031.1 - 4.1e-07 30.1 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 SLATT_2 PF18183.1 KFH46031.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 4HBT PF03061.22 KFH46033.1 - 9.9e-05 22.6 0.4 0.025 14.9 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily bZIP_1 PF00170.21 KFH46034.1 - 0.00087 19.3 2.4 0.0015 18.6 2.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFH46034.1 - 0.0023 18.0 6.4 0.0041 17.2 6.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper RINT1_TIP1 PF04437.13 KFH46035.1 - 1.3e-164 548.8 0.0 2.2e-164 548.0 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family T7SS_ESX_EspC PF10824.8 KFH46035.1 - 0.66 10.5 3.8 6.1 7.4 0.3 3.1 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Orthopox_A5L PF06193.11 KFH46035.1 - 0.73 9.2 3.0 1.3 8.4 3.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Phage_GP20 PF06810.11 KFH46035.1 - 0.84 9.4 4.4 0.7 9.7 2.3 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Borrelia_P83 PF05262.11 KFH46035.1 - 0.99 7.8 5.3 1.4 7.3 5.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DHR10 PF18595.1 KFH46035.1 - 2 8.5 11.0 0.11 12.6 3.2 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 KFH46036.1 - 2.2e-21 75.8 8.7 2.2e-21 75.8 8.7 12.5 9 1 3 13 13 13 3 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KFH46036.1 - 3.1e-10 40.2 10.0 3.1e-10 40.2 10.0 12.7 12 3 1 13 13 13 1 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.12 KFH46036.1 - 0.049 14.1 0.4 0.049 14.1 0.4 6.2 4 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KFH46036.1 - 1.9 8.5 41.5 0.65 10.0 0.5 5.8 3 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus BcrAD_BadFG PF01869.20 KFH46037.1 - 2.8e-20 72.9 0.2 2.4e-19 69.9 0.1 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KFH46037.1 - 0.00016 21.7 0.7 0.0011 18.9 0.0 2.7 2 1 0 2 2 2 1 SIS domain SIS PF01380.22 KFH46037.1 - 0.073 12.9 0.1 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 SIS domain ROK PF00480.20 KFH46037.1 - 0.091 12.2 1.9 0.24 10.8 0.3 2.3 3 0 0 3 3 3 0 ROK family zf-CCCH_4 PF18044.1 KFH46038.1 - 1.6e-10 40.5 3.6 3.9e-10 39.3 3.6 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFH46038.1 - 6.6e-07 29.2 8.0 1.5e-06 28.0 8.0 1.7 1 0 0 1 1 1 1 Zinc finger domain Nucleoporin_FG PF13634.6 KFH46038.1 - 1.1e-06 29.4 155.7 0.0012 19.6 24.9 7.2 3 1 5 8 8 8 5 Nucleoporin FG repeat region zf-CCCH PF00642.24 KFH46038.1 - 1.7e-06 27.8 2.0 3e-06 27.0 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFH46038.1 - 0.016 15.4 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFH46038.1 - 0.081 13.4 3.6 0.19 12.3 3.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3391 PF11871.8 KFH46038.1 - 0.16 12.5 0.1 0.51 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Cyclase PF04199.13 KFH46039.1 - 4.6e-13 49.6 0.0 6.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 KFH46040.1 - 0.00013 21.1 0.0 0.00026 20.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46040.1 - 4.2 7.6 11.4 0.29 11.3 6.1 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ELYS PF13934.6 KFH46042.1 - 6.1e-67 225.8 2.9 7.2e-67 225.6 2.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly LVIVD PF08309.11 KFH46043.1 - 2.6e-06 26.7 0.0 0.046 13.1 0.0 3.8 4 0 0 4 4 4 3 LVIVD repeat DUF4245 PF14030.6 KFH46043.1 - 0.068 13.2 0.2 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) CUE PF02845.16 KFH46044.1 - 4e-09 36.0 0.0 8.5e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF3384 PF11864.8 KFH46044.1 - 0.089 11.7 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) PAF-AH_p_II PF03403.13 KFH46045.1 - 3.7e-10 38.9 0.0 0.00013 20.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KFH46045.1 - 0.00019 21.1 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH46045.1 - 0.0045 16.3 0.1 0.71 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFH46045.1 - 0.099 12.4 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF498 PF04430.14 KFH46045.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) PGM_PMM_II PF02879.16 KFH46046.1 - 0.15 12.7 0.0 1.4 9.6 0.1 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II JCAD PF15351.6 KFH46047.1 - 0.056 11.2 0.0 0.1 10.3 0.0 1.3 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Glyco_transf_90 PF05686.12 KFH46050.1 - 2.3e-12 46.6 7.0 2.5e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Nop PF01798.18 KFH46051.1 - 3.9e-72 242.4 0.1 7.3e-72 241.5 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFH46051.1 - 4e-18 65.5 0.2 4e-18 65.5 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KFH46051.1 - 0.054 13.6 31.2 0.091 12.8 31.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 KFH46051.1 - 1.9 8.7 13.3 3.7 7.8 13.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 KFH46051.1 - 9.2 4.9 8.8 12 4.5 8.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Fungal_trans_2 PF11951.8 KFH46052.1 - 1.2e-56 192.2 0.1 1.8e-56 191.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46052.1 - 1.5e-09 37.8 31.2 8.6e-05 22.6 8.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KFH46052.1 - 0.0083 16.2 23.5 0.014 15.5 23.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 KFH46052.1 - 0.55 10.5 7.6 0.98 9.7 7.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Lin-8 PF03353.15 KFH46052.1 - 4.8 6.7 10.0 2.1 7.8 7.2 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Cellulase PF00150.18 KFH46053.1 - 1e-16 61.2 2.1 3.4e-16 59.5 2.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_33 PF13671.6 KFH46054.1 - 0.17 12.0 4.5 2.4 8.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain HECT PF00632.25 KFH46055.1 - 4.8e-69 233.2 0.0 6.9e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KFH46055.1 - 2.6e-09 37.2 1.9 6.4e-09 35.9 1.9 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Nuc_deoxyri_tr2 PF15891.5 KFH46056.1 - 0.00073 19.8 0.1 0.00088 19.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Gpi16 PF04113.14 KFH46057.1 - 3.7e-241 801.5 0.0 4.4e-241 801.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF4185 PF13810.6 KFH46058.1 - 2.2e-11 43.6 3.0 1.1e-10 41.2 0.9 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4185) zf-U1 PF06220.12 KFH46059.1 - 2.9e-08 33.3 0.6 4.8e-08 32.6 0.6 1.4 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.6 KFH46059.1 - 0.092 13.0 2.5 0.11 12.8 0.5 2.1 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal bZIP_1 PF00170.21 KFH46060.1 - 3.7e-06 26.9 2.7 3.7e-06 26.9 2.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor DDRGK PF09756.9 KFH46060.1 - 5.3 6.6 10.7 11 5.6 10.7 1.4 1 0 0 1 1 1 0 DDRGK domain TAS2R PF05296.13 KFH46061.1 - 0.0053 15.9 0.2 0.006 15.7 0.2 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Peptidase_M36 PF02128.15 KFH46062.1 - 6.3e-153 509.3 0.2 8.4e-153 508.9 0.2 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KFH46062.1 - 6.9e-14 51.4 6.0 1.4e-13 50.4 6.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KFH46062.1 - 5e-05 23.2 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Sec3_C PF09763.9 KFH46063.1 - 4e-234 779.1 0.0 5.2e-234 778.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KFH46063.1 - 1.6e-26 92.2 0.0 3e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KFH46063.1 - 0.056 13.8 0.2 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Vps52 PF04129.12 KFH46063.1 - 0.099 11.4 0.8 0.28 9.9 0.2 1.8 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF5020 PF16412.5 KFH46063.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) HEAT_EZ PF13513.6 KFH46064.1 - 3.9e-23 81.5 4.6 3e-09 37.2 0.0 8.3 10 0 0 10 10 9 4 HEAT-like repeat HEAT PF02985.22 KFH46064.1 - 8.3e-18 63.0 4.1 0.0013 18.8 0.0 8.9 9 0 0 9 9 8 4 HEAT repeat HEAT_2 PF13646.6 KFH46064.1 - 2.8e-17 62.9 8.3 0.035 14.5 0.0 7.8 5 3 3 8 8 8 6 HEAT repeats Adaptin_N PF01602.20 KFH46064.1 - 7.6e-09 34.6 0.0 0.0066 15.1 0.0 4.2 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFH46064.1 - 6.7e-08 33.0 0.0 0.0094 16.5 0.0 4.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFH46064.1 - 5.4e-07 29.8 0.0 0.95 9.5 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFH46064.1 - 6.7e-07 29.1 0.2 0.2 11.7 0.0 5.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KFH46064.1 - 8.7e-07 28.8 0.7 1.3e-05 25.0 0.1 3.1 3 0 0 3 3 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KFH46064.1 - 2.9e-05 23.7 0.0 0.087 12.4 0.0 3.7 3 0 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 KFH46064.1 - 0.00037 20.6 0.2 0.29 11.3 0.1 3.4 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 KFH46064.1 - 0.0007 19.5 0.0 0.5 10.3 0.0 4.1 4 0 0 4 4 4 1 UME (NUC010) domain MMS19_C PF12460.8 KFH46064.1 - 0.00072 18.8 0.4 0.22 10.6 0.1 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.12 KFH46064.1 - 0.001 18.9 0.0 2.1 8.0 0.0 3.9 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 KFH46064.1 - 0.0015 18.8 0.0 4.8 7.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 KFH46064.1 - 0.031 13.4 0.2 11 5.0 0.0 3.1 3 0 0 3 3 3 0 Dopey, N-terminal DUF3385 PF11865.8 KFH46064.1 - 0.082 12.8 0.1 11 5.9 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Tti2 PF10521.9 KFH46064.1 - 0.099 12.2 0.0 1.8 8.1 0.0 2.9 4 0 0 4 4 4 0 Tti2 family DUF2834 PF11196.8 KFH46065.1 - 0.0099 16.2 3.5 1.1 9.7 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2834) DUF812 PF05667.11 KFH46066.1 - 5.9e-05 22.2 26.1 5.9e-05 22.2 26.1 4.8 1 1 3 4 4 4 2 Protein of unknown function (DUF812) GAS PF13851.6 KFH46066.1 - 6.5e-05 22.4 22.0 6.5e-05 22.4 22.0 8.0 1 1 6 7 7 7 4 Growth-arrest specific micro-tubule binding FAM184 PF15665.5 KFH46066.1 - 0.00047 20.0 178.2 0.16 11.7 9.1 8.5 1 1 7 8 8 8 6 Family with sequence similarity 184, A and B Spc7 PF08317.11 KFH46066.1 - 0.00092 18.2 191.6 0.038 12.9 23.2 9.1 1 1 8 9 9 9 7 Spc7 kinetochore protein SlyX PF04102.12 KFH46066.1 - 0.0093 16.6 0.8 0.0093 16.6 0.8 14.1 6 2 9 16 16 16 3 SlyX DUF641 PF04859.12 KFH46066.1 - 0.0097 16.2 3.6 0.0097 16.2 3.6 12.2 2 1 10 12 12 12 3 Plant protein of unknown function (DUF641) Fez1 PF06818.15 KFH46066.1 - 0.012 16.0 12.6 0.012 16.0 12.6 8.7 1 1 8 9 9 9 0 Fez1 Fib_alpha PF08702.10 KFH46066.1 - 0.057 13.6 0.4 0.057 13.6 0.4 8.8 3 2 6 9 9 9 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KFH46066.1 - 0.26 10.8 154.1 0.011 15.4 40.2 7.5 1 1 7 8 8 8 0 Intermediate filament protein N2227 PF07942.12 KFH46067.1 - 5.3e-61 206.2 0.0 8.1e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KFH46067.1 - 0.0002 21.3 0.0 0.00075 19.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46067.1 - 0.0015 19.2 0.0 0.018 15.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46067.1 - 0.004 17.8 0.0 0.1 13.2 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Cir_Bir_Yir PF06022.11 KFH46067.1 - 0.069 12.6 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir WD40 PF00400.32 KFH46068.1 - 8.3e-40 134.0 19.4 3.3e-05 24.6 0.5 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 KFH46068.1 - 7.4e-13 48.0 0.2 2.2e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFH46068.1 - 3.5e-12 46.0 0.7 8.9e-12 44.7 0.7 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFH46068.1 - 9.3e-07 29.1 0.8 6.4 7.1 0.0 5.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PRANC PF09372.10 KFH46068.1 - 0.24 11.7 0.0 0.49 10.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Fe-ADH PF00465.19 KFH46069.1 - 1.2e-103 346.8 0.0 1.5e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFH46069.1 - 1.2e-14 54.6 0.0 5.7e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase RNA_pol_L_2 PF13656.6 KFH46069.1 - 0.04 13.7 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_51K PF01512.17 KFH46070.1 - 1.7e-47 161.1 0.0 2.6e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KFH46070.1 - 7.5e-29 99.6 2.4 8.1e-29 99.5 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KFH46070.1 - 2.3e-09 36.9 0.0 1.3e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 SLBB domain Zn_clus PF00172.18 KFH46071.1 - 8.9e-07 28.9 8.8 1.9e-06 27.9 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RSB_motif PF16294.5 KFH46071.1 - 0.11 12.8 0.8 3 8.2 0.0 2.4 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif Smr PF01713.21 KFH46072.1 - 0.0032 17.8 0.1 0.011 16.0 0.1 2.0 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 KFH46072.1 - 0.015 15.7 4.5 0.067 13.6 4.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Nebulin PF00880.18 KFH46072.1 - 0.71 9.8 4.8 1.1 9.2 0.2 2.7 2 0 0 2 2 2 0 Nebulin repeat Acetyltransf_1 PF00583.25 KFH46073.1 - 7.1e-08 32.7 0.0 1.1e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH46073.1 - 4e-07 30.0 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH46073.1 - 9.4e-06 26.0 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH46073.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Abhydrolase_3 PF07859.13 KFH46074.1 - 1e-39 136.6 0.2 1.3e-39 136.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH46074.1 - 0.04 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family HET PF06985.11 KFH46076.1 - 5.7e-26 91.6 0.0 1.6e-25 90.2 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LUC7 PF03194.15 KFH46077.1 - 1e-70 238.3 3.9 1.3e-70 238.0 3.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KFH46077.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1241 PF06840.11 KFH46077.1 - 0.029 14.0 0.0 0.061 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Ntox28 PF15605.6 KFH46077.1 - 0.13 12.5 0.5 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 28 Fungal_trans PF04082.18 KFH46079.1 - 2e-18 66.4 0.1 3e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46079.1 - 3.3e-08 33.5 10.2 6.4e-08 32.6 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Raffinose_syn PF05691.12 KFH46079.1 - 0.14 9.9 0.0 0.23 9.2 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_47 PF01532.20 KFH46080.1 - 3.1e-168 560.4 0.0 3.7e-168 560.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MIP PF00230.20 KFH46082.1 - 1.3e-44 152.6 6.3 3.3e-44 151.3 6.3 1.5 1 1 0 1 1 1 1 Major intrinsic protein Asparaginase_2 PF01112.18 KFH46083.1 - 2.2e-55 187.9 0.2 2.4e-27 95.8 0.0 3.4 3 0 0 3 3 3 3 Asparaginase Sporozoite_P67 PF05642.11 KFH46083.1 - 0.21 9.6 5.7 0.27 9.3 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HECT PF00632.25 KFH46084.1 - 1.3e-73 248.2 0.0 1.8e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KFH46084.1 - 1.1e-05 25.3 4.4 1.9 8.7 0.1 6.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFH46084.1 - 0.044 14.0 2.4 8.7 6.9 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat E2_bind PF08825.10 KFH46084.1 - 0.074 13.2 0.0 0.32 11.2 0.0 2.1 1 0 0 1 1 1 0 E2 binding domain HEAT_EZ PF13513.6 KFH46084.1 - 0.085 13.4 0.5 13 6.4 0.1 3.4 2 0 0 2 2 2 0 HEAT-like repeat MMS19_N PF14500.6 KFH46084.1 - 4.4 6.8 8.0 2.2 7.8 0.2 4.0 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Adenylsucc_synt PF00709.21 KFH46085.1 - 5.7e-155 516.4 0.0 6.9e-155 516.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ubie_methyltran PF01209.18 KFH46086.1 - 4.7e-78 261.7 0.0 5.9e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KFH46086.1 - 7.9e-17 61.8 0.0 2.9e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46086.1 - 5.5e-15 55.5 0.0 7.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46086.1 - 4.1e-14 53.0 0.0 1.7e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46086.1 - 1.8e-11 44.7 0.0 2.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH46086.1 - 1.5e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH46086.1 - 0.035 13.7 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KFH46086.1 - 0.068 13.0 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase BLM10_mid PF16507.5 KFH46087.1 - 9e-199 661.5 0.0 1.3e-198 660.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KFH46087.1 - 1e-29 102.3 0.0 6.9e-29 99.6 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KFH46087.1 - 7.1e-20 71.1 0.1 1.8e-19 69.8 0.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KFH46087.1 - 0.013 15.7 0.4 4.7 7.7 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KFH46087.1 - 0.035 14.6 0.8 12 6.6 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat IFRD PF05004.13 KFH46087.1 - 0.089 11.9 0.0 15 4.5 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Complex1_30kDa PF00329.19 KFH46088.1 - 7.2e-43 146.1 0.0 1e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2157 PF09925.9 KFH46089.1 - 0.0035 17.2 5.9 0.012 15.4 0.1 2.4 1 1 0 2 2 2 2 Predicted membrane protein (DUF2157) DUF2530 PF10745.9 KFH46089.1 - 0.043 14.1 0.5 0.043 14.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-C3HC PF07967.13 KFH46091.1 - 4.5e-40 136.8 0.1 6.1e-35 120.1 0.4 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KFH46091.1 - 1.7e-28 98.6 1.7 5.9e-27 93.7 0.0 3.0 3 0 0 3 3 3 1 Rsm1-like BIR PF00653.21 KFH46091.1 - 8.2e-05 23.2 0.2 0.012 16.2 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Sugar_tr PF00083.24 KFH46093.1 - 1e-78 265.2 23.3 1.9e-78 264.3 23.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46093.1 - 7.6e-42 143.5 42.5 1.1e-31 110.1 22.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH46093.1 - 0.00047 18.7 1.5 0.00047 18.7 1.5 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4017 PF13209.6 KFH46093.1 - 5 7.1 8.5 2.4 8.2 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) 2OG-FeII_Oxy_2 PF13532.6 KFH46094.1 - 2.3e-29 103.0 0.0 3.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KFH46096.1 - 6.7e-17 61.4 0.4 1.4e-16 60.3 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF747 PF05346.11 KFH46097.1 - 2.2e-121 405.2 4.8 2.9e-121 404.8 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family HemY_N PF07219.13 KFH46097.1 - 3.2 8.0 5.4 1.6 8.9 0.6 2.5 2 0 0 2 2 2 0 HemY protein N-terminus zf-C2H2_2 PF12756.7 KFH46098.1 - 1.5e-35 121.5 7.1 8.8e-30 103.0 0.6 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFH46098.1 - 4.3e-10 39.6 13.9 1.2e-07 31.8 1.3 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH46098.1 - 1.4e-07 31.7 6.5 1.5e-07 31.6 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFH46098.1 - 0.0002 21.9 15.4 0.83 10.7 0.4 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-DBF PF07535.12 KFH46098.1 - 0.018 15.1 8.5 0.35 11.0 0.6 3.8 4 0 0 4 4 4 0 DBF zinc finger DUF629 PF04780.12 KFH46098.1 - 0.075 11.5 1.6 0.32 9.5 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KFH46098.1 - 0.7 10.5 18.7 5.1 7.7 0.3 4.9 4 1 1 5 5 5 0 Zinc finger, C2H2 type adh_short PF00106.25 KFH46100.1 - 2.1e-42 144.8 0.6 2.7e-42 144.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46100.1 - 7e-30 104.3 0.3 9.4e-30 103.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFH46100.1 - 0.0048 16.4 0.4 0.0087 15.5 0.4 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KFH46100.1 - 0.0078 15.9 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KFH46100.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF1776 PF08643.10 KFH46100.1 - 0.014 14.8 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 KFH46100.1 - 0.059 12.7 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KFH46100.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family YdfZ PF14001.6 KFH46100.1 - 0.085 13.3 0.8 42 4.7 0.0 3.4 4 0 0 4 4 3 0 YdfZ protein ADH_zinc_N PF00107.26 KFH46100.1 - 0.12 12.3 0.2 0.4 10.7 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KFH46100.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KFH46100.1 - 0.14 12.8 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tim17 PF02466.19 KFH46102.1 - 7.9e-32 109.9 7.1 7.9e-32 109.9 7.1 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family adh_short_C2 PF13561.6 KFH46104.1 - 3.2e-57 193.8 0.0 3.7e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46104.1 - 6.3e-48 162.8 0.0 7.6e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46104.1 - 2.4e-08 34.1 0.0 3.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH46104.1 - 0.018 14.5 0.0 0.097 12.1 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Melibiase_2 PF16499.5 KFH46105.1 - 5.8e-43 147.1 0.1 1.1e-42 146.2 0.1 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFH46105.1 - 8.4e-12 45.0 1.6 1.5e-11 44.2 0.2 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFH46105.1 - 0.0075 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase TraQ PF09679.10 KFH46106.1 - 0.017 15.0 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) VIT1 PF01988.19 KFH46106.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.3 2 0 0 2 2 2 0 VIT family LysM PF01476.20 KFH46107.1 - 1.4e-10 41.0 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain Mpp10 PF04006.12 KFH46108.1 - 7.5 4.9 33.9 0.35 9.3 20.8 3.1 3 0 0 3 3 3 0 Mpp10 protein DUF4604 PF15377.6 KFH46108.1 - 8.4 6.8 36.8 0.4 11.1 18.8 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4604) Podoplanin PF05808.11 KFH46109.1 - 0.00078 19.6 0.1 0.0013 18.9 0.1 1.5 1 1 0 1 1 1 1 Podoplanin CFEM PF05730.11 KFH46109.1 - 0.0016 18.4 2.2 0.0026 17.8 2.2 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KFH46109.1 - 0.038 13.4 0.3 0.089 12.2 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TM_helix PF05552.12 KFH46109.1 - 0.13 12.3 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Conserved TM helix Rax2 PF12768.7 KFH46109.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Peptidase_M20 PF01546.28 KFH46110.1 - 6.4e-23 81.5 0.0 2.3e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KFH46110.1 - 1.3e-14 54.3 12.3 0.0045 17.8 0.0 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.14 KFH46110.1 - 2e-05 24.4 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KFH46110.1 - 0.00025 21.3 0.1 8.1 6.8 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 KFH46110.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.19 KFH46112.1 - 5.9e-29 101.4 0.0 1.8e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFH46112.1 - 2e-05 24.0 0.0 0.0018 17.6 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH46112.1 - 0.00014 21.0 0.8 0.3 10.1 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 KFH46112.1 - 0.00024 20.6 2.9 0.015 14.7 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH46112.1 - 0.00051 20.2 0.2 0.0014 18.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFH46112.1 - 0.0012 17.6 0.2 0.084 11.6 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KFH46112.1 - 0.0029 18.1 0.2 0.07 13.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH46112.1 - 0.0058 15.9 0.1 0.063 12.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH46112.1 - 0.019 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFH46112.1 - 0.02 14.5 4.2 0.05 13.2 1.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH46112.1 - 0.021 14.2 0.5 0.04 13.2 0.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFH46112.1 - 0.027 13.6 0.3 0.05 12.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFH46112.1 - 0.051 12.4 0.1 0.051 12.4 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase TetR_C_11 PF16859.5 KFH46112.1 - 0.065 13.6 3.1 0.13 12.6 3.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Trp_leader2 PF08056.11 KFH46112.1 - 0.13 12.3 0.5 0.27 11.3 0.5 1.5 1 0 0 1 1 1 0 Tryptophan operon leader peptide PTPA PF03095.15 KFH46113.1 - 3.2e-118 394.6 0.0 3.7e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Peptidase_S58 PF03576.14 KFH46115.1 - 1.4e-108 363.0 3.1 1.7e-108 362.6 3.1 1.1 1 0 0 1 1 1 1 Peptidase family S58 Hexapep PF00132.24 KFH46116.1 - 2.9e-07 30.0 9.0 0.0081 15.9 0.5 4.4 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFH46116.1 - 0.018 14.8 12.4 3.2 7.6 0.1 4.3 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Peptidase_S9 PF00326.21 KFH46117.1 - 3.8e-05 23.2 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFH46117.1 - 5.3e-05 22.8 5.5 0.0011 18.6 0.1 3.3 2 1 0 2 2 2 2 Esterase PHB depolymerase adh_short PF00106.25 KFH46118.1 - 2e-32 112.3 0.0 4.1e-32 111.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46118.1 - 6.4e-24 84.8 0.0 9.3e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH46118.1 - 7e-05 22.8 0.1 0.0002 21.3 0.1 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFH46118.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFH46118.1 - 0.018 15.0 0.0 0.077 12.9 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_2 PF03446.15 KFH46118.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PEX11 PF05648.14 KFH46119.1 - 2e-22 79.8 1.7 1.6e-21 76.9 1.7 2.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CDC27 PF09507.10 KFH46120.1 - 0.00021 20.8 19.8 0.00031 20.2 19.8 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TFIIA PF03153.13 KFH46120.1 - 0.088 12.8 10.8 0.12 12.3 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 KFH46120.1 - 5.2 5.6 9.7 6.9 5.2 9.7 1.1 1 0 0 1 1 1 0 Hamartin protein Nucleo_P87 PF07267.11 KFH46120.1 - 6.2 5.6 11.9 8.3 5.1 11.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF5345 PF17280.2 KFH46121.1 - 0.0074 16.2 6.0 0.16 11.9 0.1 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5345) DUF4175 PF13779.6 KFH46121.1 - 5 4.9 9.5 0.15 9.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) 3HCDH PF00725.22 KFH46122.1 - 5e-22 78.3 0.0 1.1e-21 77.3 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 KFH46122.1 - 5.4e-22 78.5 0.0 1.1e-21 77.6 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFH46122.1 - 0.0013 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KFH46122.1 - 0.011 15.4 0.0 0.03 14.0 0.1 1.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KFH46122.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fasciclin PF02469.22 KFH46123.1 - 4.8e-44 149.7 0.0 1.7e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Complex1_LYR PF05347.15 KFH46124.1 - 2.9e-08 33.6 0.0 2.9e-08 33.6 0.0 2.3 3 0 0 3 3 3 1 Complex 1 protein (LYR family) E1_dh PF00676.20 KFH46126.1 - 2.8e-84 282.6 0.0 3.4e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFH46126.1 - 0.00061 19.6 0.0 0.0083 15.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FGGY_C PF02782.16 KFH46127.1 - 1.7e-72 243.3 1.0 2.7e-72 242.7 1.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFH46127.1 - 7.1e-67 225.5 0.0 9.6e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFH46127.1 - 0.029 13.9 0.4 4 6.9 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Asparaginase_2 PF01112.18 KFH46128.1 - 1.1e-69 234.8 1.2 1.4e-69 234.4 1.2 1.0 1 0 0 1 1 1 1 Asparaginase DUF2433 PF10360.9 KFH46129.1 - 2.4e-49 166.6 0.4 8.3e-49 164.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) Zds_C PF08632.10 KFH46129.1 - 5.1e-29 99.8 0.7 8.7e-29 99.0 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Metallophos PF00149.28 KFH46129.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH46129.1 - 0.0067 16.6 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DAO PF01266.24 KFH46131.1 - 1.6e-49 169.4 0.1 2.3e-49 168.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFH46131.1 - 7.7e-39 132.4 0.0 2.1e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KFH46131.1 - 7e-08 32.0 1.4 0.0019 17.3 0.6 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KFH46131.1 - 0.00042 19.8 1.3 0.00078 18.9 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH46131.1 - 0.00092 18.5 0.3 0.0042 16.4 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFH46131.1 - 0.047 13.6 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KFH46131.1 - 0.071 12.2 0.2 3.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KFH46131.1 - 0.091 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFH46131.1 - 0.12 11.6 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFH46131.1 - 0.19 10.8 0.2 1.1 8.3 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-RING_4 PF14570.6 KFH46132.1 - 7.4e-20 70.5 12.2 1.4e-19 69.6 12.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KFH46132.1 - 2.5e-08 33.6 0.0 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KFH46132.1 - 1.4e-07 31.3 6.8 3.1e-07 30.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KFH46132.1 - 5.1e-05 22.8 2.2 5.1e-05 22.8 2.2 3.1 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KFH46132.1 - 0.00028 21.2 10.0 0.00057 20.2 10.0 1.6 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 KFH46132.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 KFH46132.1 - 0.0038 17.0 8.8 0.18 11.7 10.0 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Nup35_RRM_2 PF14605.6 KFH46132.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 KFH46132.1 - 0.092 12.7 5.0 0.16 11.9 5.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 KFH46132.1 - 0.1 12.5 10.3 0.27 11.1 10.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFH46132.1 - 0.14 12.3 3.5 0.31 11.2 3.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 KFH46132.1 - 0.14 12.3 4.6 0.31 11.2 4.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 KFH46132.1 - 0.31 11.0 10.3 0.56 10.2 10.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH46132.1 - 1.3 8.9 9.9 3.5 7.6 9.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PcrB PF01884.17 KFH46133.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.5 1 1 1 2 2 2 0 PcrB family A_deaminase PF00962.22 KFH46134.1 - 1.2e-24 87.2 0.0 4.9e-20 72.1 0.0 2.3 2 1 0 2 2 2 2 Adenosine/AMP deaminase DUF3046 PF11248.8 KFH46134.1 - 0.14 12.6 0.2 0.5 10.8 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Ion_trans_2 PF07885.16 KFH46135.1 - 3.4e-34 116.6 25.8 1.2e-18 66.8 4.8 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFH46135.1 - 4.1e-05 22.9 7.8 0.0014 17.9 0.1 2.5 2 1 0 2 2 2 2 Ion transport protein DUF1513 PF07433.11 KFH46135.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Lambda_CIII PF02061.16 KFH46135.1 - 1.3 9.2 5.4 2 8.5 0.2 2.9 3 0 0 3 3 3 0 Lambda Phage CIII SRP40_C PF05022.12 KFH46136.1 - 7e-20 71.7 0.7 7e-20 71.7 0.7 3.0 3 0 0 3 3 3 1 SRP40, C-terminal domain MMR_HSR1 PF01926.23 KFH46138.1 - 2.8e-16 59.6 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFH46138.1 - 3.2e-09 37.0 0.0 0.0036 17.4 0.0 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFH46138.1 - 5.3e-07 29.4 0.0 7.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KFH46138.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFH46138.1 - 0.016 15.2 0.4 0.23 11.4 0.5 2.5 2 1 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KFH46138.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.18 KFH46138.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.16 KFH46138.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 AIG1 family CNH PF00780.22 KFH46139.1 - 7.1e-73 245.6 0.0 2.3e-72 243.9 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KFH46139.1 - 9.8e-42 142.3 0.0 2.1e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFH46139.1 - 2.7e-34 119.0 0.0 4.8e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFH46139.1 - 1.3e-15 57.2 0.1 2.6e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CI-B14_5a PF07347.12 KFH46140.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AUX_IAA PF02309.16 KFH46141.1 - 0.087 12.7 0.8 9 6.1 0.2 2.2 2 0 0 2 2 2 0 AUX/IAA family ADH_zinc_N PF00107.26 KFH46142.1 - 1.5e-13 50.8 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH46142.1 - 0.0044 18.1 0.0 0.0073 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DLH PF01738.18 KFH46142.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family adh_short PF00106.25 KFH46143.1 - 1.4e-34 119.3 0.0 1.9e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46143.1 - 9.3e-23 81.0 0.0 9e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH46143.1 - 0.075 12.9 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 KR domain eIF-5a PF01287.20 KFH46144.1 - 5.6e-08 32.8 0.1 1.1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 KFH46144.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.6 1 1 2 3 3 3 0 Chitin synthesis regulation, resistance to Congo red NmrA PF05368.13 KFH46145.1 - 1.8e-23 83.4 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH46145.1 - 3.4e-15 56.4 0.1 6.4e-15 55.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFH46145.1 - 0.013 14.9 0.1 1.3 8.4 0.0 2.4 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KFH46145.1 - 0.047 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.18 KFH46146.1 - 3.1e-09 36.3 0.1 4.9e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46146.1 - 0.00095 19.2 2.3 0.00095 19.2 2.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_106 PF17132.4 KFH46147.1 - 2.9e-36 125.1 0.0 3.9e-28 98.2 0.0 2.7 1 1 1 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 KFH46147.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GATase_7 PF13537.6 KFH46148.1 - 3.5e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFH46148.1 - 2.6e-09 37.4 0.0 4.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFH46148.1 - 0.00021 20.8 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 KFH46149.1 - 1.9e-14 53.9 0.0 2.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Auxin_inducible PF02519.14 KFH46149.1 - 0.014 15.5 0.0 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 Auxin responsive protein Glyco_hydro81C PF17652.1 KFH46150.1 - 1.7e-151 504.4 13.4 2.2e-151 504.1 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KFH46150.1 - 1e-113 379.8 2.0 1.4e-113 379.3 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DUF4813 PF16072.5 KFH46150.1 - 0.29 10.8 7.1 0.79 9.3 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Glyco_hydro_2_C PF02836.17 KFH46151.1 - 3.4e-102 341.6 0.6 4.7e-102 341.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFH46151.1 - 6.7e-62 209.3 0.0 1.6e-61 208.0 0.0 1.6 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFH46151.1 - 2.7e-48 164.1 1.2 3.7e-48 163.6 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFH46151.1 - 6.6e-24 84.2 0.6 2e-23 82.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFH46151.1 - 1.1e-05 26.1 0.0 6.1e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Big_9 PF17963.1 KFH46151.1 - 0.089 13.6 0.1 0.33 11.7 0.1 2.1 1 0 0 1 1 1 0 Bacterial Ig domain BetaGal_dom4_5 PF13364.6 KFH46151.1 - 0.097 13.2 1.1 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Exo_endo_phos PF03372.23 KFH46152.1 - 3.1e-06 26.9 0.0 6.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4148 PF13663.6 KFH46152.1 - 0.027 14.6 1.9 0.069 13.3 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) SLATT_fungal PF18142.1 KFH46153.1 - 5.9e-27 94.0 0.0 8.3e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Acetyltransf_1 PF00583.25 KFH46154.1 - 1e-12 48.3 0.1 1.3e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH46154.1 - 3.4e-08 33.8 0.0 5.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH46154.1 - 5.9e-08 32.7 0.0 8.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFH46154.1 - 0.01 16.5 0.0 0.024 15.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFH46154.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KFH46154.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KFH46156.1 - 1.5e-13 50.4 23.6 8e-09 34.9 3.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily SpoVAB PF13782.6 KFH46156.1 - 7.6 6.9 13.7 10 6.5 3.9 3.6 3 0 0 3 3 3 0 Stage V sporulation protein AB Lustrin_cystein PF14625.6 KFH46157.1 - 0.25 11.8 11.9 15 6.1 11.9 2.2 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain RabGAP-TBC PF00566.18 KFH46158.1 - 3.2e-47 161.0 0.0 5.8e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KFH46158.1 - 5.1e-07 29.1 0.3 0.076 13.0 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFH46158.1 - 4.6e-06 25.8 0.7 0.07 12.7 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFH46158.1 - 0.00093 19.6 1.6 0.0021 18.5 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair GRAM PF02893.20 KFH46158.1 - 0.0053 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 KFH46158.1 - 0.011 15.2 0.2 2.4 7.8 0.1 2.9 2 0 0 2 2 2 0 EF hand R3H-assoc PF13902.6 KFH46158.1 - 7.2 7.0 6.4 0.96 9.8 0.1 2.7 3 0 0 3 3 3 0 R3H-associated N-terminal domain Ribosomal_L7Ae PF01248.26 KFH46159.1 - 8e-22 76.8 2.1 1e-21 76.5 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ComGG PF14173.6 KFH46159.1 - 0.0045 17.4 0.0 1 9.8 0.0 3.1 3 0 0 3 3 3 1 ComG operon protein 7 RRM_Rrp7 PF17799.1 KFH46159.1 - 0.13 12.1 0.9 0.25 11.2 0.9 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain E1_UFD PF09358.10 KFH46159.1 - 0.31 11.8 3.3 41 5.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin fold domain PV-1 PF06637.11 KFH46159.1 - 4.1 6.1 10.2 6.6 5.4 10.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CDC45 PF02724.14 KFH46160.1 - 5.1 5.3 7.5 7.4 4.7 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NIF PF03031.18 KFH46161.1 - 1.3e-41 141.9 0.0 2.2e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC2_membrane PF01061.24 KFH46163.1 - 9.4e-80 267.0 53.4 1.1e-41 142.6 26.5 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFH46163.1 - 8e-34 117.1 3.1 2.3e-16 60.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFH46163.1 - 8.6e-27 92.9 2.2 9.5e-23 79.9 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KFH46163.1 - 4.3e-16 59.3 1.1 4.3e-16 59.3 1.1 2.3 1 1 1 2 2 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 KFH46163.1 - 1.5e-06 28.2 0.4 0.0038 17.1 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFH46163.1 - 5.8e-06 26.3 0.7 0.00021 21.2 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KFH46163.1 - 7.4e-06 26.4 0.1 0.0012 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFH46163.1 - 1.2e-05 25.5 0.1 0.0023 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFH46163.1 - 0.00016 21.4 2.1 0.42 10.4 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFH46163.1 - 0.00024 21.2 0.1 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFH46163.1 - 0.00034 20.9 0.1 0.17 12.2 0.1 3.3 4 0 0 4 4 2 1 AAA domain cobW PF02492.19 KFH46163.1 - 0.00037 20.1 0.2 0.028 14.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KFH46163.1 - 0.0014 18.9 0.0 0.004 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH46163.1 - 0.0015 19.1 0.0 0.049 14.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KFH46163.1 - 0.0025 17.4 0.1 0.27 10.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KFH46163.1 - 0.0027 16.9 11.3 0.0027 16.9 11.3 3.3 4 0 0 4 4 3 1 ABC-2 family transporter protein SMC_N PF02463.19 KFH46163.1 - 0.0071 15.8 3.8 0.14 11.5 0.0 3.6 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFH46163.1 - 0.015 15.0 0.2 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFH46163.1 - 0.018 15.0 0.2 0.4 10.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 KFH46163.1 - 0.023 13.9 0.2 2.3 7.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KFH46163.1 - 0.025 14.3 0.1 0.43 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KFH46163.1 - 0.059 12.7 0.4 6.1 6.1 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KFH46163.1 - 0.099 13.1 0.7 14 6.1 0.1 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) GBP PF02263.19 KFH46163.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Zeta_toxin PF06414.12 KFH46163.1 - 0.13 11.5 0.2 0.71 9.1 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KFH46163.1 - 0.13 11.5 1.1 0.51 9.6 0.1 2.2 3 0 0 3 3 2 0 Septin TsaE PF02367.17 KFH46163.1 - 0.13 12.2 0.3 0.63 10.1 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KFH46163.1 - 0.4 10.7 1.6 3 7.9 0.0 2.8 3 0 0 3 3 2 0 Dynamin family Filo_glycop PF01611.16 KFH46164.1 - 0.024 13.6 0.5 0.041 12.8 0.5 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein MOLO1 PF17175.4 KFH46165.1 - 0.16 12.1 0.2 1.2 9.3 0.0 1.9 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 Nse4_C PF08743.10 KFH46166.1 - 9.9e-32 109.1 0.0 2.5e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KFH46166.1 - 2.8e-19 69.0 4.7 3.4e-19 68.7 0.0 3.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PBP1_TM PF14812.6 KFH46166.1 - 0.51 10.7 15.5 0.36 11.2 1.0 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 KFH46166.1 - 1.9 7.2 10.7 0.63 8.8 2.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HET PF06985.11 KFH46167.1 - 1.8e-24 86.8 0.0 4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PQQ_2 PF13360.6 KFH46167.1 - 0.0069 16.0 0.0 0.022 14.3 0.0 1.7 1 1 1 2 2 2 1 PQQ-like domain DUF3703 PF12487.8 KFH46167.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) MGTL PF17059.5 KFH46167.1 - 0.13 12.1 3.4 2.6 8.0 0.0 2.8 2 0 0 2 2 2 0 MgtA leader peptide UcrQ PF02939.16 KFH46168.1 - 2.2e-32 110.8 0.5 2.6e-32 110.6 0.5 1.0 1 0 0 1 1 1 1 UcrQ family Pkinase PF00069.25 KFH46169.1 - 8.9e-13 48.2 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46169.1 - 3.9e-06 26.3 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LpoB PF13036.6 KFH46169.1 - 0.17 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Yae1_N PF09811.9 KFH46170.1 - 2e-10 40.2 5.6 3.1e-10 39.6 5.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_S28e PF01200.18 KFH46170.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S28e SCO1-SenC PF02630.14 KFH46170.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC AAA_18 PF13238.6 KFH46171.1 - 2.6e-07 31.3 0.0 7.1e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFH46171.1 - 4.5e-06 26.5 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KFH46171.1 - 3e-05 23.3 0.0 9.1e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KFH46171.1 - 4.2e-05 23.7 0.0 8.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFH46171.1 - 7.8e-05 23.1 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFH46171.1 - 8e-05 23.1 0.4 0.033 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH46171.1 - 9.5e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH46171.1 - 0.00051 20.5 0.0 0.00093 19.6 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KFH46171.1 - 0.00098 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 KFH46171.1 - 0.0017 18.1 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase SKI PF01202.22 KFH46171.1 - 0.0022 18.2 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase MeaB PF03308.16 KFH46171.1 - 0.0023 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DnaB_C PF03796.15 KFH46171.1 - 0.003 16.9 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_30 PF13604.6 KFH46171.1 - 0.0037 17.0 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFH46171.1 - 0.0045 17.5 0.0 0.0065 17.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.10 KFH46171.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 KFH46171.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KFH46171.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KFH46171.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.12 KFH46171.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain APS_kinase PF01583.20 KFH46171.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KFH46171.1 - 0.035 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 KFH46171.1 - 0.037 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFH46171.1 - 0.047 14.0 0.0 0.065 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFH46171.1 - 0.056 13.2 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 KFH46171.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KFH46171.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 KFH46171.1 - 0.12 12.3 0.3 0.35 10.8 0.0 1.9 3 0 0 3 3 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KFH46171.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 KFH46171.1 - 0.13 12.4 1.3 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_14 PF13173.6 KFH46171.1 - 0.19 11.8 0.0 0.92 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4336 PF14234.6 KFH46172.1 - 1.1e-14 54.3 0.0 4e-10 39.4 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) PRELI PF04707.14 KFH46173.1 - 4.6e-18 65.5 0.0 3.2e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family IF-2B PF01008.17 KFH46174.1 - 6.5e-41 140.4 0.3 8.7e-40 136.7 0.3 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family Globin PF00042.22 KFH46174.1 - 0.034 14.7 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Globin MSA-2c PF12238.8 KFH46174.1 - 5 7.1 7.3 9.5 6.2 7.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c MID_MedPIWI PF18296.1 KFH46176.1 - 0.0054 16.6 0.1 0.0078 16.0 0.1 1.2 1 0 0 1 1 1 1 MID domain of medPIWI NFACT-C PF11923.8 KFH46178.1 - 2.9e-42 142.9 0.4 2.9e-42 142.9 0.4 3.7 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 KFH46178.1 - 3.1e-33 115.2 10.1 3.1e-33 115.2 10.1 2.2 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KFH46178.1 - 2.1e-31 108.8 0.0 5.1e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain GREB1 PF15782.5 KFH46178.1 - 2.5 5.1 10.4 4.5 4.3 10.4 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ATP-synt_C PF00137.21 KFH46179.1 - 9.2e-29 99.6 36.7 2.9e-18 65.9 14.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 KFH46179.1 - 0.059 12.8 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 AhpC-TSA PF00578.21 KFH46180.1 - 1.9e-25 89.2 0.0 2.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFH46180.1 - 1.6e-15 57.1 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFH46180.1 - 0.019 15.1 0.0 0.28 11.3 0.0 2.3 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme PI3Ka PF00613.20 KFH46181.1 - 1.9e-57 193.7 0.3 3.1e-57 193.0 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFH46181.1 - 2.2e-46 158.7 0.1 4e-31 108.7 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KFH46181.1 - 5.4e-30 104.1 0.0 8.9e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 KFH46181.1 - 0.00049 20.3 0.0 0.0044 17.3 0.0 2.3 2 0 0 2 2 2 1 C2 domain Peptidase_C1_2 PF03051.15 KFH46182.1 - 2e-145 485.0 0.0 2.3e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFH46182.1 - 3.6e-06 27.2 0.1 0.014 15.5 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease adh_short_C2 PF13561.6 KFH46184.1 - 1.1e-55 188.8 0.1 1.5e-55 188.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46184.1 - 1.1e-38 132.7 0.2 1.6e-38 132.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46184.1 - 3.7e-13 49.8 0.1 5.3e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFH46184.1 - 0.00036 20.0 0.0 0.0051 16.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KFH46184.1 - 0.036 13.9 0.0 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KFH46184.1 - 0.056 12.9 0.1 0.095 12.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family bZIP_1 PF00170.21 KFH46185.1 - 0.0051 16.9 3.9 0.0088 16.1 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF4387 PF14330.6 KFH46186.1 - 8.4e-33 113.0 0.0 1.9e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KFH46186.1 - 9.2e-14 50.9 0.0 1.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Beta-lactamase PF00144.24 KFH46187.1 - 5.7e-35 121.1 0.0 8.4e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Lipase_GDSL PF00657.22 KFH46188.1 - 2.6e-12 47.2 0.0 3.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFH46188.1 - 2e-06 28.3 0.0 3.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Chitin_synth_1 PF01644.17 KFH46189.1 - 1.1e-73 246.5 0.1 1.9e-73 245.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFH46189.1 - 1.4e-28 98.6 0.1 3.2e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFH46189.1 - 5.5e-23 81.4 0.3 6.5e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFH46189.1 - 4.4e-07 30.0 2.0 4.4e-07 30.0 2.0 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Pkinase PF00069.25 KFH46192.1 - 2.8e-26 92.5 0.0 3.5e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46192.1 - 7.7e-14 51.6 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH46192.1 - 4.7e-09 35.5 0.0 6.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFH46192.1 - 0.0002 21.4 0.0 0.0015 18.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family AATase PF07247.12 KFH46193.1 - 4.9e-14 51.8 0.0 1e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 Alcohol acetyltransferase Tri3 PF07428.11 KFH46193.1 - 0.012 14.6 0.1 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 Bac_rhamnosid_C PF17390.2 KFH46193.1 - 0.021 14.6 0.0 1.8 8.4 0.0 3.4 3 1 0 3 3 3 0 Bacterial alpha-L-rhamnosidase C-terminal domain FAD_binding_3 PF01494.19 KFH46194.1 - 3.5e-22 79.1 1.4 2.9e-18 66.3 0.0 2.1 1 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFH46194.1 - 6.3e-12 45.3 0.2 0.00011 21.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH46194.1 - 5.5e-08 32.4 0.0 8.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH46194.1 - 3.3e-06 26.9 5.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH46194.1 - 9.6e-06 24.5 1.2 0.0052 15.5 0.7 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KFH46194.1 - 9.6e-06 24.9 1.4 1.4e-05 24.4 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KFH46194.1 - 1.3e-05 24.3 3.0 0.00023 20.2 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KFH46194.1 - 2.4e-05 24.8 1.4 0.18 12.4 1.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH46194.1 - 0.00038 19.6 0.7 0.0034 16.5 0.7 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KFH46194.1 - 0.00044 19.5 0.9 0.0014 17.8 0.9 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KFH46194.1 - 0.00069 19.0 0.2 0.11 11.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH46194.1 - 0.00077 19.6 2.4 0.0022 18.2 0.8 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH46194.1 - 0.0098 15.2 0.4 0.016 14.5 0.4 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KFH46194.1 - 0.011 14.8 0.0 0.18 10.9 0.0 2.3 2 1 1 3 3 3 0 Squalene epoxidase FAD_oxidored PF12831.7 KFH46194.1 - 0.022 14.1 0.7 0.033 13.5 0.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFH46194.1 - 0.099 11.9 0.7 2.5 7.4 0.5 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 KFH46197.1 - 9.4e-43 146.4 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH46197.1 - 8.1e-14 51.9 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH46197.1 - 0.048 13.1 0.1 0.074 12.5 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 KFH46197.1 - 0.13 13.0 0.1 0.34 11.6 0.1 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 KFH46197.1 - 0.17 10.9 0.1 0.32 10.0 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pal1 PF08316.11 KFH46198.1 - 2.1e-46 158.1 1.3 8.8e-46 156.1 1.3 2.1 1 1 0 1 1 1 1 Pal1 cell morphology protein Fungal_trans PF04082.18 KFH46199.1 - 6.4e-16 58.2 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46199.1 - 1.4e-08 34.7 10.6 2.8e-08 33.8 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFH46200.1 - 5.1e-98 328.9 28.0 6.4e-98 328.6 28.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46200.1 - 2.3e-36 125.4 62.2 5.9e-27 94.5 39.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 KFH46200.1 - 0.044 14.4 0.5 1.8 9.2 0.0 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3792 PF12670.7 KFH46200.1 - 7.5 6.8 28.6 14 5.9 12.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) DUF1761 PF08570.10 KFH46202.1 - 4.3e-28 98.1 1.8 4.9e-28 97.9 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Hexapep PF00132.24 KFH46203.1 - 1.5e-08 34.0 8.5 1.7e-05 24.4 1.3 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFH46203.1 - 2.4e-06 27.2 0.8 0.00018 21.2 0.2 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFH46203.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Imm64 PF15600.6 KFH46204.1 - 0.22 11.1 0.0 0.47 10.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 64 DUF3455 PF11937.8 KFH46205.1 - 3.2e-25 89.4 0.0 4.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Acetyltransf_1 PF00583.25 KFH46206.1 - 6.5e-12 45.7 0.0 9.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH46206.1 - 4.6e-08 33.0 0.1 7e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH46206.1 - 9.2e-07 28.7 0.1 1.7e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFH46206.1 - 1.4e-05 25.4 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH46206.1 - 0.018 15.1 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFH46206.1 - 0.026 14.0 0.7 0.044 13.2 0.7 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase DUF913 PF06025.12 KFH46208.1 - 0.19 10.7 0.5 0.35 9.8 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Med19 PF10278.9 KFH46208.1 - 1.2 9.0 8.6 2.3 8.1 8.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Coilin_N PF15862.5 KFH46208.1 - 1.4 8.8 7.0 2.6 7.9 5.5 2.1 2 0 0 2 2 2 0 Coilin N-terminus PRELI PF04707.14 KFH46209.1 - 1e-40 139.1 0.2 1.2e-40 138.8 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family Band_7 PF01145.25 KFH46210.1 - 1.1e-24 87.4 6.3 1.1e-24 87.4 6.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KFH46210.1 - 0.00015 20.9 5.8 0.0002 20.5 5.8 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 KFH46210.1 - 0.14 12.3 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain LMWPc PF01451.21 KFH46211.1 - 7.2e-38 130.2 0.0 8.1e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sugar_tr PF00083.24 KFH46212.1 - 4.1e-59 200.6 18.5 4.8e-59 200.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46212.1 - 3.5e-20 72.2 37.3 2.3e-17 63.0 28.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 KFH46213.1 - 5e-44 150.5 0.1 6.3e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 KFH46213.1 - 0.052 13.7 7.7 0.093 12.8 7.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein REV PF00424.18 KFH46213.1 - 0.54 10.3 1.7 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CDC45 PF02724.14 KFH46213.1 - 7.3 4.8 6.8 11 4.2 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HTH_48 PF17906.1 KFH46214.1 - 0.048 13.8 0.0 12 6.1 0.0 2.2 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF676 PF05057.14 KFH46215.1 - 1.1e-51 175.4 0.0 1.6e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KFH46215.1 - 4.5e-05 23.4 0.0 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFH46215.1 - 0.00018 21.3 0.0 0.0031 17.3 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFH46215.1 - 0.0015 19.2 0.2 0.016 15.8 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF4611 PF15387.6 KFH46215.1 - 0.0093 16.2 0.3 0.017 15.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Abhydrolase_1 PF00561.20 KFH46215.1 - 0.073 12.7 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFH46215.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Annexin PF00191.20 KFH46216.1 - 6.9e-20 70.9 0.2 7.9e-05 22.7 0.0 4.7 4 0 0 4 4 4 4 Annexin AhpC-TSA_2 PF13911.6 KFH46217.1 - 7e-16 58.4 0.0 1.6e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFH46217.1 - 8.5e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFH46217.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin Dicty_REP PF05086.12 KFH46217.1 - 4.2 5.2 5.2 5.4 4.9 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KFH46217.1 - 4.5 7.3 31.2 7.1 6.6 31.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.16 KFH46218.1 - 1.1e-37 129.9 31.4 1.1e-37 129.9 31.4 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily FeoB_C PF07664.12 KFH46218.1 - 1.9 8.2 6.2 1 9.1 0.0 3.5 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus NAP PF00956.18 KFH46219.1 - 4.7e-101 337.5 11.3 4.7e-101 337.5 11.3 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 KFH46219.1 - 0.014 16.0 2.7 0.014 16.0 2.7 2.6 2 1 0 2 2 2 0 Striatin family Ras PF00071.22 KFH46220.1 - 4.9e-46 156.3 0.1 5.5e-46 156.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH46220.1 - 9e-16 58.2 0.0 1.2e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH46220.1 - 1.1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFH46220.1 - 0.00011 21.8 0.0 0.0004 20.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFH46220.1 - 0.0028 17.7 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH46220.1 - 0.0044 16.9 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFH46220.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KFH46220.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFH46220.1 - 0.037 13.6 0.0 0.38 10.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KFH46220.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short_C2 PF13561.6 KFH46221.1 - 1.3e-35 123.1 0.0 1.5e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46221.1 - 2.2e-29 102.3 0.1 3e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46221.1 - 0.0042 17.0 0.1 0.0066 16.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Tropomyosin_1 PF12718.7 KFH46222.1 - 5.7e-51 172.4 38.7 6.9e-51 172.2 38.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KFH46222.1 - 1.4e-06 27.8 36.6 0.00025 20.5 15.8 3.0 1 1 2 3 3 3 3 Tropomyosin DUF3450 PF11932.8 KFH46222.1 - 0.00034 20.0 30.4 0.0056 16.0 13.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFH46222.1 - 0.00043 20.6 36.6 0.019 15.2 12.5 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 KFH46222.1 - 0.00084 19.7 38.4 0.013 15.8 16.9 2.7 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KFH46222.1 - 0.0012 18.8 7.5 0.0012 18.8 7.5 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KFH46222.1 - 0.0016 18.8 23.1 0.14 12.5 4.5 4.3 3 1 1 4 4 4 3 Flagella accessory protein C (FlaC) HMMR_N PF15905.5 KFH46222.1 - 0.002 17.7 32.4 0.0024 17.4 32.4 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Taxilin PF09728.9 KFH46222.1 - 0.0043 16.3 31.9 0.12 11.6 10.9 2.2 1 1 1 2 2 2 2 Myosin-like coiled-coil protein TACC_C PF05010.14 KFH46222.1 - 0.0044 16.8 16.2 0.0044 16.8 16.2 2.2 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal bZIP_1 PF00170.21 KFH46222.1 - 0.0062 16.6 32.9 0.013 15.6 2.2 4.8 2 1 2 4 4 4 2 bZIP transcription factor Laminin_II PF06009.12 KFH46222.1 - 0.0062 16.6 5.4 0.0062 16.6 5.4 2.1 1 1 1 2 2 2 1 Laminin Domain II Uso1_p115_C PF04871.13 KFH46222.1 - 0.0073 16.7 38.5 0.018 15.4 16.7 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region ERM PF00769.19 KFH46222.1 - 0.008 16.0 42.3 0.011 15.6 20.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DivIC PF04977.15 KFH46222.1 - 0.0082 15.9 3.8 0.0082 15.9 3.8 4.3 2 1 2 4 4 4 2 Septum formation initiator Rab5-bind PF09311.11 KFH46222.1 - 0.0093 15.4 28.0 0.021 14.2 12.4 2.1 1 1 1 2 2 2 1 Rabaptin-like protein Fez1 PF06818.15 KFH46222.1 - 0.016 15.7 29.0 0.027 14.9 29.0 1.4 1 0 0 1 1 1 0 Fez1 DUF724 PF05266.14 KFH46222.1 - 0.016 15.0 10.9 0.016 15.0 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KFH46222.1 - 0.016 14.5 36.8 0.074 12.4 17.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 KFH46222.1 - 0.021 14.5 28.4 0.91 9.2 11.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ZapB PF06005.12 KFH46222.1 - 0.024 15.1 44.7 0.37 11.3 7.3 4.4 1 1 3 4 4 4 0 Cell division protein ZapB Spc7 PF08317.11 KFH46222.1 - 0.028 13.3 37.3 0.021 13.7 23.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 KFH46222.1 - 0.033 14.3 35.4 0.049 13.7 7.9 4.2 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 KLRAQ PF10205.9 KFH46222.1 - 0.034 14.4 26.6 0.17 12.1 7.1 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein KASH_CCD PF14662.6 KFH46222.1 - 0.034 14.0 35.7 0.029 14.2 32.4 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 KFH46222.1 - 0.035 13.7 37.1 0.42 10.2 21.4 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 KFH46222.1 - 0.036 14.1 35.9 0.58 10.3 11.8 2.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase MAD PF05557.13 KFH46222.1 - 0.038 12.3 32.5 0.23 9.8 8.9 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein HALZ PF02183.18 KFH46222.1 - 0.055 13.7 0.6 0.055 13.7 0.6 4.8 5 1 0 5 5 4 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 KFH46222.1 - 0.057 14.0 20.9 1.6 9.3 10.1 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal GIT_CC PF16559.5 KFH46222.1 - 0.079 12.8 20.2 0.15 12.0 3.6 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phage_GP20 PF06810.11 KFH46222.1 - 0.085 12.7 31.7 1.4 8.7 3.5 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 CALCOCO1 PF07888.11 KFH46222.1 - 0.1 11.5 34.2 0.88 8.4 17.6 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 KFH46222.1 - 0.13 12.4 35.9 0.17 11.9 10.2 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFH46222.1 - 0.15 12.0 41.0 0.95 9.5 15.9 3.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding CEP63 PF17045.5 KFH46222.1 - 0.18 11.7 28.6 0.22 11.4 28.6 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa bZIP_2 PF07716.15 KFH46222.1 - 0.25 11.4 43.0 0.36 10.9 1.8 5.7 2 2 4 6 6 6 0 Basic region leucine zipper XhlA PF10779.9 KFH46222.1 - 0.28 11.4 33.5 1.8 8.8 2.1 4.0 2 2 2 4 4 4 0 Haemolysin XhlA APG6_N PF17675.1 KFH46222.1 - 0.31 11.5 45.4 0.41 11.2 29.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 KFH46222.1 - 0.35 9.7 28.0 0.046 12.6 12.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CASP_C PF08172.12 KFH46222.1 - 0.49 9.7 25.7 0.14 11.4 2.8 2.1 1 1 1 2 2 2 0 CASP C terminal DUF4472 PF14739.6 KFH46222.1 - 0.51 11.1 31.8 0.26 12.0 13.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 KFH46222.1 - 0.61 10.4 24.6 0.54 10.6 1.3 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T3SSipB PF16535.5 KFH46222.1 - 0.88 10.0 23.2 4.8 7.6 13.1 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 KFH46222.1 - 0.98 9.6 37.6 0.22 11.8 23.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 KFH46222.1 - 1.1 6.7 31.5 1.7 6.0 31.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4686 PF15742.5 KFH46222.1 - 1.2 8.2 36.5 0.82 8.7 22.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) SHE3 PF17078.5 KFH46222.1 - 1.3 8.7 31.1 0.18 11.5 3.6 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 TPR_MLP1_2 PF07926.12 KFH46222.1 - 1.4 9.0 41.9 11 6.1 13.2 3.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 KFH46222.1 - 1.4 9.6 28.6 8.8 7.0 2.0 3.5 1 1 3 4 4 4 0 Initiation control protein YabA MPS2 PF17060.5 KFH46222.1 - 1.4 8.1 16.2 1.9 7.7 16.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 CHDCT2 PF08074.11 KFH46222.1 - 1.6 8.9 12.7 0.18 12.0 6.5 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Sec34 PF04136.15 KFH46222.1 - 2 8.3 18.2 0.54 10.1 5.4 2.3 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KFH46222.1 - 2.1 8.4 17.2 1 9.4 5.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CtIP_N PF10482.9 KFH46222.1 - 2.2 8.4 29.3 0.099 12.7 7.3 3.0 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain PRKG1_interact PF15898.5 KFH46222.1 - 2.6 9.0 32.5 1.6 9.7 15.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4618 PF15397.6 KFH46222.1 - 2.6 7.4 28.0 0.45 9.9 18.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Leu_zip PF15294.6 KFH46222.1 - 3.5 7.1 27.6 14 5.1 27.6 1.8 1 1 0 1 1 1 0 Leucine zipper TMF_TATA_bd PF12325.8 KFH46222.1 - 3.5 7.9 33.0 8.4 6.6 6.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding KELK PF15796.5 KFH46222.1 - 3.7 8.1 36.9 0.37 11.3 4.0 3.8 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SOGA PF11365.8 KFH46222.1 - 5.9 8.1 28.1 5.8 8.1 12.1 3.4 1 1 2 3 3 3 0 Protein SOGA CENP-K PF11802.8 KFH46222.1 - 5.9 6.4 24.6 1.9 8.0 7.7 2.1 1 1 1 2 2 2 0 Centromere-associated protein K HAP1_N PF04849.13 KFH46222.1 - 6 6.0 35.0 1e+02 1.9 35.0 2.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CLZ PF16526.5 KFH46222.1 - 6.7 7.1 29.6 56 4.2 8.7 3.7 1 1 1 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 KFH46222.1 - 7.8 4.9 9.7 9.1 4.7 9.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.10 KFH46222.1 - 8.3 6.7 27.5 2.8 8.2 6.2 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil TolA_bind_tri PF16331.5 KFH46222.1 - 9.3 6.4 26.3 0.58 10.3 1.8 4.1 2 1 2 4 4 4 0 TolA binding protein trimerisation Peptidase_C78 PF07910.13 KFH46223.1 - 4.9e-60 202.6 0.0 1.5e-59 201.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 KFH46223.1 - 0.025 14.9 0.1 0.025 14.9 0.1 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Dynamin_N PF00350.23 KFH46224.1 - 8.2e-44 149.6 0.0 1.6e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH46224.1 - 1.8e-14 53.6 0.3 3.3e-12 46.2 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KFH46224.1 - 2e-05 24.7 0.2 0.00023 21.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRI PF08236.11 KFH46224.1 - 0.015 15.4 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_21 PF13304.6 KFH46224.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFH46224.1 - 0.063 13.7 1.6 0.18 12.1 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 KFH46224.1 - 0.1 12.3 0.6 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KFH46225.1 - 2.6e-29 102.4 0.1 4.5e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFH46225.1 - 3.5e-08 34.0 0.0 1.8e-07 31.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFH46225.1 - 5e-05 23.1 0.2 0.075 12.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KFH46225.1 - 5.1e-05 23.5 0.1 0.0061 16.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain ADK PF00406.22 KFH46225.1 - 6.8e-05 23.0 0.0 0.0041 17.2 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 KFH46225.1 - 7.6e-05 22.7 0.4 0.00015 21.7 0.1 1.6 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 KFH46225.1 - 0.00011 22.5 2.3 0.00022 21.5 2.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH46225.1 - 0.00012 22.6 0.0 0.00022 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KFH46225.1 - 0.00013 21.9 1.2 0.061 13.2 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 KFH46225.1 - 0.00025 21.5 0.0 0.0005 20.5 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KFH46225.1 - 0.0003 21.1 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KFH46225.1 - 0.00038 20.0 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 KFH46225.1 - 0.00066 20.0 0.0 0.0014 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFH46225.1 - 0.0043 17.4 0.0 0.0077 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase SKI PF01202.22 KFH46225.1 - 0.0044 17.1 0.5 0.061 13.5 0.5 2.0 1 1 0 1 1 1 1 Shikimate kinase TrwB_AAD_bind PF10412.9 KFH46225.1 - 0.0064 15.4 0.0 0.04 12.8 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KFH46225.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KFH46225.1 - 0.017 14.9 0.6 0.034 13.9 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KFH46225.1 - 0.019 15.0 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFH46225.1 - 0.021 14.5 0.1 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KFH46225.1 - 0.022 14.5 1.8 0.55 9.9 0.5 2.4 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 KFH46225.1 - 0.031 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 KFH46225.1 - 0.036 14.4 0.1 0.036 14.4 0.1 1.9 3 0 0 3 3 1 0 AAA domain Viral_helicase1 PF01443.18 KFH46225.1 - 0.04 13.7 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 KFH46225.1 - 0.048 13.8 0.0 0.093 12.9 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family T2SSE PF00437.20 KFH46225.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KFH46225.1 - 0.061 13.0 0.3 0.061 13.0 0.3 2.1 2 2 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KFH46225.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFH46225.1 - 0.069 12.9 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 KFH46225.1 - 0.07 12.9 0.2 0.13 12.0 0.0 1.5 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KFH46225.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 KFH46225.1 - 0.11 11.8 0.3 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KFH46225.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arnt_C PF18583.1 KFH46225.1 - 0.25 11.0 2.5 19 4.9 0.4 3.0 2 1 1 3 3 3 0 Aminoarabinose transferase C-terminal domain PIG-Y PF15159.6 KFH46226.1 - 5.4e-23 81.7 7.9 8e-23 81.1 7.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KFH46226.1 - 0.065 13.8 1.8 0.77 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 KFH46226.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) Peptidase_M19 PF01244.21 KFH46227.1 - 1.5e-97 326.7 0.0 1.8e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Nop25 PF09805.9 KFH46228.1 - 4.4e-43 147.0 12.2 4.4e-43 147.0 12.2 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Lys-AminoMut_A PF09043.11 KFH46228.1 - 0.17 10.3 1.0 0.26 9.7 1.0 1.3 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF4202 PF13875.6 KFH46229.1 - 8.5e-75 250.8 0.0 9.6e-75 250.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF2732 PF10809.8 KFH46229.1 - 0.074 12.9 0.1 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) BTB PF00651.31 KFH46230.1 - 1.9e-05 24.8 0.0 5.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KFH46230.1 - 0.12 12.5 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain N-SET PF11764.8 KFH46231.1 - 1.1e-51 175.3 7.4 2.1e-51 174.5 0.0 3.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KFH46231.1 - 1e-24 85.9 0.2 1e-24 85.9 0.2 2.4 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 KFH46231.1 - 5.5e-20 72.4 0.1 5.5e-20 72.4 0.1 2.9 3 0 0 3 3 3 1 SET domain IGR PF09597.10 KFH46232.1 - 2.9e-26 91.3 0.5 6.8e-26 90.1 0.5 1.7 1 0 0 1 1 1 1 IGR protein motif zf-MYND PF01753.18 KFH46233.1 - 2.7e-07 30.6 20.6 2.7e-07 30.6 20.6 2.0 2 0 0 2 2 2 1 MYND finger AMP-binding PF00501.28 KFH46234.1 - 1.1e-89 301.0 0.0 1.4e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH46234.1 - 3.1e-11 44.1 0.1 7.6e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.14 KFH46234.1 - 0.2 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) bZIP_2 PF07716.15 KFH46235.1 - 0.00076 19.5 11.9 0.0011 18.9 11.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFH46235.1 - 0.083 13.0 9.6 0.14 12.3 9.6 1.2 1 0 0 1 1 1 0 bZIP transcription factor Pro_isomerase PF00160.21 KFH46236.1 - 2.5e-49 167.6 0.3 3.1e-49 167.3 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Polyketide_cyc PF03364.20 KFH46237.1 - 9.4e-25 87.3 0.1 1.4e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_S28 PF05577.12 KFH46238.1 - 4.8e-38 131.1 0.2 2.6e-30 105.6 0.2 2.9 2 1 0 2 2 2 2 Serine carboxypeptidase S28 DUF3966 PF13110.6 KFH46238.1 - 0.22 11.4 0.3 0.47 10.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Fur_reg_FbpB PF13040.6 KFH46238.1 - 0.23 11.0 0.2 0.63 9.6 0.0 1.7 2 0 0 2 2 2 0 Fur-regulated basic protein B Cyanate_lyase PF02560.14 KFH46239.1 - 3.2e-31 107.0 0.0 4.8e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KFH46239.1 - 0.0079 16.5 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4866 PF16160.5 KFH46239.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Head-tail_con PF12236.8 KFH46240.1 - 0.059 11.8 0.8 0.074 11.5 0.8 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Abhydrolase_1 PF00561.20 KFH46242.1 - 1.1e-26 94.0 0.0 7.5e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH46242.1 - 2.8e-14 54.3 0.0 4.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH46242.1 - 1.4e-10 40.9 0.0 3e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFH46242.1 - 1.7e-05 24.6 0.1 0.18 11.5 0.1 2.2 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 KFH46242.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KFH46242.1 - 0.00024 20.8 0.0 0.00047 19.9 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Palm_thioest PF02089.15 KFH46242.1 - 0.012 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KFH46242.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 KFH46242.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase CTP_transf_like PF01467.26 KFH46243.1 - 0.0098 16.1 1.8 0.21 11.8 1.8 2.3 1 1 0 1 1 1 1 Cytidylyltransferase-like Pheromone PF08015.11 KFH46243.1 - 0.08 14.0 4.4 1.4 10.1 0.0 4.1 4 0 0 4 4 4 0 Fungal mating-type pheromone FAD_syn PF06574.12 KFH46243.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Aldedh PF00171.22 KFH46244.1 - 6.3e-161 536.0 0.0 7.2e-161 535.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFH46244.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ATP-synt_S1 PF05827.12 KFH46245.1 - 4.3e-06 26.6 0.1 6.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) FMN_dh PF01070.18 KFH46246.1 - 7.4e-117 390.3 0.1 8.4e-117 390.1 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFH46246.1 - 1.7e-05 24.0 1.2 0.00028 20.0 0.5 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFH46246.1 - 8.8e-05 21.8 0.6 0.00024 20.4 0.5 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KFH46246.1 - 0.00018 21.0 0.2 0.00032 20.2 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KFH46246.1 - 0.0021 17.4 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KFH46246.1 - 0.15 11.2 0.4 14 4.7 0.0 2.9 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Mid1 PF12929.7 KFH46247.1 - 1.6e-135 452.6 0.6 1.9e-135 452.3 0.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KFH46247.1 - 5.9e-05 23.7 4.7 0.038 14.6 0.8 2.4 2 0 0 2 2 2 2 Fz domain MFS_1 PF07690.16 KFH46248.1 - 4.4e-33 114.7 38.6 1.7e-32 112.7 37.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily SMAP PF15477.6 KFH46249.1 - 2e-07 31.8 2.2 2e-07 31.8 2.2 5.7 3 2 0 3 3 3 1 Small acidic protein family 7tm_1 PF00001.21 KFH46250.1 - 1.7 7.9 6.4 0.21 10.9 1.9 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) adh_short_C2 PF13561.6 KFH46251.1 - 3.8e-58 196.8 0.1 4.6e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46251.1 - 1.1e-47 162.0 0.3 1.3e-47 161.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46251.1 - 1.6e-12 47.7 0.3 2e-12 47.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH46251.1 - 0.0039 16.7 0.1 0.015 14.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KFH46251.1 - 0.005 17.5 0.0 0.012 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoHcyase_NAD PF00670.21 KFH46251.1 - 0.075 13.1 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eisosome1 PF12757.7 KFH46252.1 - 2.4e-38 131.2 11.6 2.4e-38 131.2 11.6 4.5 4 1 1 5 5 5 1 Eisosome protein 1 SIKE PF05769.11 KFH46253.1 - 0.13 12.2 1.2 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 SIKE family GDPD_2 PF13653.6 KFH46254.1 - 0.054 14.0 0.4 0.11 12.9 0.4 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family AA_kinase PF00696.28 KFH46255.1 - 2.1e-33 115.9 0.0 5.4e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KFH46255.1 - 4.1e-13 48.9 1.5 3.8e-07 29.8 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KFH46255.1 - 6.5e-13 48.3 5.2 3.7e-09 36.3 0.3 2.9 2 1 1 3 3 3 2 ACT domain RAMP4 PF06624.12 KFH46256.1 - 4.8e-12 45.8 5.1 1.7e-06 28.0 0.5 2.0 2 0 0 2 2 2 2 Ribosome associated membrane protein RAMP4 TRAP_alpha PF03896.16 KFH46257.1 - 9.9e-08 31.5 0.0 1.5e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit UQ_con PF00179.26 KFH46259.1 - 4.4e-19 68.5 0.0 7.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFH46259.1 - 0.0085 16.4 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF2072 PF09845.9 KFH46259.1 - 0.053 13.8 0.5 0.078 13.2 0.5 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein Fungal_trans PF04082.18 KFH46260.1 - 2.8e-20 72.5 0.0 4.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46260.1 - 0.00013 22.0 10.5 0.00024 21.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KFH46261.1 - 3.7e-47 160.4 0.0 5.4e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH46261.1 - 2.3e-29 102.0 0.2 6.4e-29 100.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH46261.1 - 6.6e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Terminase_6 PF03237.15 KFH46261.1 - 0.14 11.7 0.1 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Terminase-like family Cation_efflux PF01545.21 KFH46262.1 - 4.7e-12 46.1 15.6 6.3e-12 45.7 15.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5504 PF17608.2 KFH46262.1 - 0.47 10.6 2.1 0.91 9.6 0.0 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5504) PP2C PF00481.21 KFH46263.1 - 1.6e-34 119.7 0.0 2.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFH46263.1 - 0.0011 18.9 0.0 4.1 7.3 0.0 3.3 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) B-block_TFIIIC PF04182.12 KFH46264.1 - 6.6e-12 45.4 0.0 1.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC AT_hook PF02178.19 KFH46264.1 - 0.0004 19.9 41.4 0.22 11.5 5.2 5.0 4 0 0 4 4 4 4 AT hook motif MarR_2 PF12802.7 KFH46264.1 - 0.08 12.8 0.6 0.8 9.6 0.1 3.0 4 0 0 4 4 4 0 MarR family RFX5_DNA_bdg PF14621.6 KFH46264.1 - 3.7 7.3 22.3 3.5 7.4 3.1 3.3 1 1 1 3 3 3 0 RFX5 DNA-binding domain FMO-like PF00743.19 KFH46265.1 - 7.6e-18 64.2 0.1 6.4e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH46265.1 - 2.4e-12 46.9 0.0 6.5e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFH46265.1 - 1.7e-06 27.5 0.0 0.032 13.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFH46265.1 - 1.7e-05 24.8 0.0 7e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFH46265.1 - 0.0013 18.1 0.0 0.037 13.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF4188 PF13826.6 KFH46265.1 - 0.015 15.6 0.0 0.53 10.6 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4188) DAO PF01266.24 KFH46265.1 - 0.032 13.8 0.0 0.11 12.1 0.0 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFH46265.1 - 0.036 13.3 0.0 0.52 9.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Pyr_redox_2 PF07992.14 KFH46265.1 - 0.037 13.3 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GTP_CH_N PF12471.8 KFH46267.1 - 2.3e-67 226.5 0.0 3.2e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KFH46267.1 - 1e-14 54.5 0.0 2.8e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 KFH46267.1 - 0.043 13.5 0.1 3.2 7.5 0.0 3.2 4 0 0 4 4 4 0 Bacterial regulatory proteins, gntR family Methyltransf_12 PF08242.12 KFH46268.1 - 9.3e-14 52.0 0.0 2.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH46268.1 - 2.6e-13 50.5 0.0 4.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46268.1 - 4.1e-11 43.4 0.0 8.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH46268.1 - 1.4e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46268.1 - 4e-06 26.7 0.0 7.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH46268.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KFH46268.1 - 0.00099 20.1 0.0 0.0023 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFH46268.1 - 0.0035 17.2 0.0 0.087 12.7 0.0 2.6 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KFH46268.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KFH46268.1 - 0.072 12.3 0.0 7.7 5.6 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family RsgA_N PF16745.5 KFH46268.1 - 0.084 12.6 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 RsgA N-terminal domain DUF3298 PF11738.8 KFH46268.1 - 0.11 13.5 0.4 1.5 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) 2-Hacid_dh_C PF02826.19 KFH46270.1 - 3.4e-53 179.6 0.0 5.3e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH46270.1 - 1.7e-34 118.4 0.1 2.3e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFH46270.1 - 2.5e-06 27.8 1.7 8.3e-06 26.1 0.3 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFH46270.1 - 0.00063 19.4 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KFH46270.1 - 0.00087 19.4 0.1 0.002 18.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KFH46270.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 KFH46270.1 - 0.028 14.9 0.1 0.088 13.3 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Rossmann-like PF10727.9 KFH46270.1 - 0.077 12.9 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Rossmann-like domain Elf1 PF05129.13 KFH46271.1 - 2e-25 88.7 3.0 3.9e-25 87.7 3.0 1.5 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 KFH46271.1 - 0.0051 16.2 1.0 0.0082 15.5 1.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cys_rich_CPXG PF14255.6 KFH46271.1 - 0.071 13.0 1.4 0.13 12.2 1.4 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-Sec23_Sec24 PF04810.15 KFH46271.1 - 0.24 11.5 0.2 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Pkinase PF00069.25 KFH46272.1 - 1.6e-62 211.3 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46272.1 - 3.8e-34 118.1 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH46272.1 - 0.0044 16.4 0.0 0.0094 15.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like SfsA PF03749.13 KFH46272.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain P5-ATPase PF12409.8 KFH46273.1 - 8.6e-40 135.7 0.0 2e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFH46273.1 - 3.3e-28 98.4 0.0 7.4e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFH46273.1 - 5.1e-15 56.3 0.0 4.6e-09 36.9 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFH46273.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus WAPL PF07814.13 KFH46274.1 - 2.1e-48 165.0 0.2 3.5e-48 164.2 0.2 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Spb1_C PF07780.12 KFH46275.1 - 2e-80 269.4 23.2 2e-80 269.4 23.2 3.5 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KFH46275.1 - 1e-55 188.6 0.0 2.1e-55 187.6 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KFH46275.1 - 9.7e-52 175.1 13.1 9.7e-52 175.1 13.1 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KFH46275.1 - 0.039 13.8 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFH46275.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F tRNA-synt_2b PF00587.25 KFH46276.1 - 5.4e-29 101.4 0.0 8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFH46276.1 - 1.9e-19 69.9 5.5 1.9e-19 69.9 5.5 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Ribosomal_S13 PF00416.22 KFH46278.1 - 6.4e-19 68.6 0.9 8.3e-17 61.8 0.9 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 CC190 PF15768.5 KFH46278.1 - 0.077 13.0 0.2 0.095 12.8 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Ham1p_like PF01725.16 KFH46280.1 - 2.6e-54 184.0 0.0 4.7e-54 183.2 0.0 1.4 1 1 0 1 1 1 1 Ham1 family Sterol-sensing PF12349.8 KFH46281.1 - 3.9e-36 124.2 11.3 9.1e-36 123.0 11.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFH46281.1 - 6.9e-11 41.0 9.4 1.1e-10 40.4 9.4 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KFH46281.1 - 0.077 13.9 0.3 2.9 8.9 0.1 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat GTP_CH_N PF12471.8 KFH46282.1 - 8.7e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DUF892 PF05974.12 KFH46282.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3618 PF12277.8 KFH46282.1 - 0.49 10.7 2.4 0.81 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Ribosomal_S3Ae PF01015.18 KFH46285.1 - 8.9e-85 283.4 1.7 1.1e-84 283.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KFH46285.1 - 0.015 15.8 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor SUI1 Erythro-docking PF09277.11 KFH46285.1 - 0.031 14.2 0.2 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking NEMO PF11577.8 KFH46285.1 - 0.07 13.2 0.6 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ebp2 PF05890.12 KFH46286.1 - 1.6e-97 326.3 9.6 1.6e-97 326.3 9.6 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Acyl-CoA_dh_1 PF00441.24 KFH46287.1 - 4.6e-23 82.1 0.1 7.5e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH46287.1 - 1.2e-12 48.4 0.7 2.2e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFH46287.1 - 6.6e-10 39.1 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFH46287.1 - 4.7e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.23 KFH46288.1 - 2.2e-60 204.2 0.0 4.7e-60 203.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KFH46288.1 - 8.8e-10 38.3 10.9 1.8e-09 37.2 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH46288.1 - 3e-09 37.1 10.2 5.6e-09 36.2 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFH46288.1 - 7.2e-09 35.4 9.3 1.5e-08 34.3 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH46288.1 - 1.4e-06 28.1 9.8 2.7e-06 27.2 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH46288.1 - 1.2e-05 25.1 9.3 2.5e-05 24.0 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFH46288.1 - 4.5e-05 23.6 7.8 0.00014 22.1 7.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFH46288.1 - 0.00013 21.8 10.3 0.00025 21.0 10.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 KFH46288.1 - 0.00014 22.2 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KFH46288.1 - 0.00036 20.5 4.4 0.00038 20.4 2.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFH46288.1 - 0.042 14.0 9.0 0.091 12.9 9.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFH46288.1 - 0.14 12.0 6.4 0.39 10.5 6.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EF-hand_2 PF09068.11 KFH46288.1 - 0.15 12.2 0.4 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 EF hand Fib_alpha PF08702.10 KFH46288.1 - 0.27 11.4 8.6 0.12 12.5 2.3 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_IE-1 PF05290.11 KFH46288.1 - 0.3 11.0 2.6 0.74 9.8 2.6 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 KFH46288.1 - 0.3 11.3 6.1 0.68 10.1 6.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Flagellin_N PF00669.20 KFH46288.1 - 1.1 9.3 6.2 2.8 8.1 0.9 3.0 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region zf-ANAPC11 PF12861.7 KFH46288.1 - 1.4 9.0 7.5 5.1 7.2 7.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFH46288.1 - 1.5 8.5 7.7 3.4 7.4 7.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type GldM_N PF12081.8 KFH46288.1 - 3.4 7.7 11.1 30 4.6 3.3 3.9 2 2 1 3 3 3 0 GldM N-terminal domain DZR PF12773.7 KFH46288.1 - 5.4 7.1 6.6 15 5.7 6.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon CsbD PF05532.12 KFH46289.1 - 2.4e-06 27.3 9.1 0.0036 17.2 1.6 2.1 2 0 0 2 2 2 2 CsbD-like PAPS_reduct PF01507.19 KFH46291.1 - 4.7e-30 104.9 0.0 5.3e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family CmcI PF04989.12 KFH46291.1 - 0.039 13.6 0.0 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Cephalosporin hydroxylase Y_phosphatase3 PF13350.6 KFH46292.1 - 1.9e-39 136.0 1.2 9.3e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Myotub-related PF06602.14 KFH46292.1 - 0.01 14.8 0.1 0.017 14.0 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFH46292.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFH46292.1 - 0.12 11.9 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Cupin_8 PF13621.6 KFH46293.1 - 9.3e-62 209.0 0.0 1.1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFH46293.1 - 0.0002 20.9 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 KFH46293.1 - 0.012 16.0 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Peptidase_M90 PF06167.12 KFH46297.1 - 0.59 9.7 3.2 5.1 6.6 3.2 2.0 1 1 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Frag1 PF10277.9 KFH46298.1 - 1e-42 146.2 18.4 1.2e-42 146.0 18.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family GWT1 PF06423.12 KFH46298.1 - 1.4 9.0 6.5 1.1 9.4 4.6 1.9 1 1 1 2 2 2 0 GWT1 Pox_P21 PF05313.12 KFH46298.1 - 2.3 7.7 5.1 1 8.9 0.3 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Trm112p PF03966.16 KFH46299.1 - 8.2e-17 61.6 0.1 1.1e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 KFH46299.1 - 0.051 14.1 0.3 0.098 13.2 0.3 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain TB2_DP1_HVA22 PF03134.19 KFH46301.1 - 7e-27 93.2 9.0 1.2e-26 92.5 9.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Alpha_GJ PF03229.13 KFH46302.1 - 0.027 15.0 4.4 0.027 15.0 4.4 2.2 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF2749 PF10907.8 KFH46302.1 - 0.13 12.4 0.4 0.37 11.0 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Pilin_N PF07790.11 KFH46302.1 - 1.2 10.1 4.0 3.9 8.5 4.0 2.0 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal ExoD PF06055.12 KFH46303.1 - 0.14 11.5 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD 14-3-3 PF00244.20 KFH46304.1 - 3.9e-06 26.5 0.1 7.4e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 14-3-3 protein OGFr_III PF04680.13 KFH46304.1 - 0.056 14.0 0.5 0.19 12.3 0.5 1.9 1 0 0 1 1 1 0 Opioid growth factor receptor repeat EF-hand_1 PF00036.32 KFH46306.1 - 1.8e-39 130.3 16.3 1.1e-09 37.2 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFH46306.1 - 3.1e-34 116.6 15.7 2.6e-15 56.0 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 KFH46306.1 - 1.7e-32 111.7 6.1 2.7e-17 63.0 2.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFH46306.1 - 4.9e-31 104.0 12.5 1.1e-09 37.4 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFH46306.1 - 4e-26 89.3 14.9 6.3e-07 28.6 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFH46306.1 - 1.3e-18 67.0 0.2 3.3e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFH46306.1 - 3.2e-12 46.3 0.7 3.9e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFH46306.1 - 1.7e-07 31.5 0.1 0.01 16.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KFH46306.1 - 5.1e-06 26.4 0.0 0.09 12.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.16 KFH46306.1 - 0.00029 21.2 1.3 0.036 14.4 0.4 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb4 TerB PF05099.13 KFH46306.1 - 0.0013 18.7 0.0 0.058 13.4 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 KFH46306.1 - 0.0017 18.6 0.2 0.18 12.2 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 KFH46306.1 - 0.0018 18.3 0.5 0.5 10.3 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein EF-hand_11 PF08976.11 KFH46306.1 - 0.0043 17.9 0.0 0.032 15.1 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain DUF2267 PF10025.9 KFH46306.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF1456 PF07308.13 KFH46306.1 - 0.019 15.3 0.4 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Fe_hyd_lg_C PF02906.14 KFH46306.1 - 0.033 13.9 0.1 0.069 12.8 0.1 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF3349 PF11829.8 KFH46306.1 - 0.046 14.5 0.0 6.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Arc_PepC PF06819.11 KFH46306.1 - 0.051 13.7 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Acetyltransf_11 PF13720.6 KFH46306.1 - 0.061 13.8 0.0 1.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 dCache_2 PF08269.11 KFH46306.1 - 0.1 11.8 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Cache domain DUF853 PF05872.12 KFH46306.1 - 0.11 11.1 0.1 5.7 5.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Dockerin_1 PF00404.18 KFH46306.1 - 0.11 12.7 2.9 2 8.7 0.2 2.6 2 1 0 2 2 2 0 Dockerin type I domain DUF5580 PF17743.1 KFH46306.1 - 0.14 10.7 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RNase_PH_C PF03725.15 KFH46306.1 - 0.37 10.8 3.1 2.1 8.4 3.1 2.4 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF3008 PF11450.8 KFH46306.1 - 1.1 9.4 6.1 2.6 8.3 0.3 3.2 3 1 0 4 4 3 0 Protein of unknwon function (DUF3008) Mst1_SARAH PF11629.8 KFH46306.1 - 1.5 8.9 4.1 6 7.0 0.6 2.9 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 RFX_DNA_binding PF02257.15 KFH46307.1 - 6.5e-27 94.0 0.1 2.1e-26 92.3 0.1 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain TFIIA PF03153.13 KFH46307.1 - 0.0092 16.0 13.2 0.012 15.6 13.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 KFH46309.1 - 2e-58 197.7 0.0 2.3e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46309.1 - 1.9e-46 158.0 0.0 2.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46309.1 - 1.7e-09 37.9 0.1 2.5e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Yop-YscD_ppl PF16693.5 KFH46309.1 - 0.012 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain Ldh_1_N PF00056.23 KFH46309.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFH46309.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KFH46309.1 - 0.12 11.7 0.2 2.7 7.3 0.1 2.4 1 1 1 2 2 2 0 ThiF family Sec10 PF07393.11 KFH46310.1 - 1.9e-156 522.5 0.0 2.4e-156 522.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KFH46310.1 - 1.7e-06 27.8 0.1 4.4e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH46310.1 - 5e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain ANAPC_CDC26 PF10471.9 KFH46310.1 - 1 10.2 8.3 2.8 8.8 8.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 RhoGAP PF00620.27 KFH46312.1 - 6.2e-17 61.8 0.0 1.6e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KFH46312.1 - 2.9e-11 43.2 0.0 6.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KFH46312.1 - 9.6e-10 38.6 0.3 3.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PI_PP_C PF18365.1 KFH46312.1 - 0.012 15.6 0.6 0.5 10.4 0.0 3.2 3 1 1 4 4 4 0 Phosphoinositide phosphatase C-terminal domain SUIM_assoc PF16619.5 KFH46312.1 - 0.65 10.1 7.2 0.31 11.1 4.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Adaptin_N PF01602.20 KFH46315.1 - 1.1e-73 248.6 0.0 2.8e-73 247.3 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFH46315.1 - 0.028 14.5 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AbiEi_3 PF11459.8 KFH46315.1 - 0.12 12.1 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system HEAT_EZ PF13513.6 KFH46315.1 - 0.49 11.0 4.2 29 5.3 0.1 4.0 4 0 0 4 4 4 0 HEAT-like repeat RNA_polI_A34 PF08208.11 KFH46315.1 - 3.2 7.8 17.6 8.9 6.3 17.6 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TPR_2 PF07719.17 KFH46316.1 - 4.1e-07 29.6 0.0 0.0013 18.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFH46316.1 - 5e-07 30.1 0.1 2.2e-05 24.8 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFH46316.1 - 2.8e-06 27.9 0.4 0.0019 18.8 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH46316.1 - 5.9e-06 26.1 0.1 0.073 13.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFH46316.1 - 3e-05 24.4 0.3 9.1 7.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFH46316.1 - 3.6e-05 24.2 9.1 0.017 15.9 0.2 5.0 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFH46316.1 - 6.5e-05 22.7 0.2 0.85 9.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH46316.1 - 9.7e-05 22.0 0.0 0.16 11.6 0.0 3.5 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 KFH46316.1 - 0.0014 18.4 0.0 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 KFH46316.1 - 0.0027 17.7 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF627) TPR_12 PF13424.6 KFH46316.1 - 0.031 14.6 3.0 3.1 8.1 0.5 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat HTH_16 PF12645.7 KFH46316.1 - 0.032 14.3 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_20 PF14561.6 KFH46316.1 - 0.053 13.9 2.7 1.9 8.9 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Phycobilisome PF00502.19 KFH46316.1 - 0.076 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome protein BTAD PF03704.17 KFH46316.1 - 0.46 10.9 5.2 2.1 8.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Brix PF04427.18 KFH46317.1 - 9.6e-50 169.4 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain CNDH2_C PF16858.5 KFH46317.1 - 0.24 11.3 10.0 0.39 10.5 10.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1910 PF08928.10 KFH46317.1 - 0.5 10.4 2.6 1.1 9.3 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PPL5 PF18168.1 KFH46317.1 - 0.99 8.6 6.0 1.9 7.7 6.0 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Myosin_head PF00063.21 KFH46318.1 - 6.1e-261 867.4 0.7 9.9e-261 866.8 0.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KFH46318.1 - 2.5e-26 92.0 2.4 2.5e-26 92.0 2.4 3.0 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 KFH46318.1 - 2.3e-11 42.5 40.3 0.00015 21.2 1.9 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KFH46318.1 - 0.00025 20.8 3.1 0.00028 20.6 0.8 2.2 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain CALCOCO1 PF07888.11 KFH46318.1 - 0.0018 17.2 22.3 0.0033 16.3 22.3 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_22 PF13401.6 KFH46318.1 - 0.005 17.1 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sec34 PF04136.15 KFH46318.1 - 0.0091 15.9 4.3 0.027 14.3 4.3 1.9 1 0 0 1 1 1 1 Sec34-like family GAS PF13851.6 KFH46318.1 - 0.013 14.9 26.9 0.013 14.9 14.4 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 KFH46318.1 - 0.013 14.4 21.5 0.022 13.7 21.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_16 PF13191.6 KFH46318.1 - 0.018 15.4 0.1 0.24 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain HSF_DNA-bind PF00447.17 KFH46318.1 - 0.094 13.3 0.5 0.37 11.4 0.5 2.0 1 0 0 1 1 1 0 HSF-type DNA-binding Baculo_PEP_C PF04513.12 KFH46318.1 - 0.16 12.0 5.2 0.13 12.3 2.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.11 KFH46318.1 - 0.27 11.3 5.0 7.5 6.7 0.4 3.0 2 0 0 2 2 2 0 Vps51/Vps67 Flagellin_N PF00669.20 KFH46318.1 - 0.41 10.7 11.2 0.042 13.9 5.1 2.5 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF4164 PF13747.6 KFH46318.1 - 0.6 10.4 11.0 7.4 6.9 11.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) KASH_CCD PF14662.6 KFH46318.1 - 1.3 8.8 27.6 1.1 9.1 8.1 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5082 PF16888.5 KFH46318.1 - 1.5 9.1 17.3 4.5 7.6 8.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) ING PF12998.7 KFH46318.1 - 2.1 9.0 7.1 0.83 10.3 2.6 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CENP-H PF05837.12 KFH46318.1 - 2.9 8.3 25.9 6.9 7.1 6.3 2.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Tropomyosin_1 PF12718.7 KFH46318.1 - 3.1 8.0 26.2 0.95 9.6 6.6 2.8 1 1 1 2 2 2 0 Tropomyosin like TMCO5 PF14992.6 KFH46318.1 - 3.3 7.2 17.3 7.7 6.0 17.3 1.6 1 0 0 1 1 1 0 TMCO5 family DUF3450 PF11932.8 KFH46318.1 - 5 6.4 23.1 7.4 5.8 5.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 KFH46318.1 - 7.8 6.3 15.2 1.3 8.9 5.9 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 UPRTase PF14681.6 KFH46319.1 - 1.2e-78 263.3 0.0 1.5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFH46319.1 - 0.0015 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DND1_DSRM PF14709.7 KFH46320.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 HECT PF00632.25 KFH46321.1 - 7.4e-78 262.1 0.0 1.1e-77 261.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFH46321.1 - 0.012 15.4 0.6 0.036 13.9 0.6 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif NMO PF03060.15 KFH46322.1 - 3e-52 178.0 0.1 2.3e-51 175.1 0.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFH46322.1 - 3e-12 46.2 0.0 1.5e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFH46322.1 - 0.018 14.1 0.2 0.033 13.2 0.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Acetyltransf_17 PF17668.1 KFH46324.1 - 0.032 15.1 0.7 0.044 14.6 0.7 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transket_pyr PF02779.24 KFH46325.1 - 4.1e-41 140.6 0.0 7.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFH46325.1 - 8.7e-32 109.6 0.0 2.1e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KFH46325.1 - 0.001 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II p450 PF00067.22 KFH46326.1 - 1.4e-38 132.8 0.0 2.4e-38 132.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Copper-fist PF00649.18 KFH46327.1 - 1.2e-11 43.9 1.2 3.1e-11 42.6 1.2 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain PhyH PF05721.13 KFH46328.1 - 4.3e-07 30.4 0.1 7.2e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PAP1 PF08601.10 KFH46329.1 - 5.9e-64 217.1 56.0 4.6e-46 158.2 0.0 4.0 2 1 2 4 4 3 3 Transcription factor PAP1 bZIP_1 PF00170.21 KFH46329.1 - 2.9e-09 36.9 12.3 7.3e-09 35.6 12.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor CENP-F_leu_zip PF10473.9 KFH46329.1 - 0.0011 19.0 2.0 0.0011 19.0 2.0 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KFH46329.1 - 0.0024 17.9 12.9 0.0075 16.3 12.9 1.8 1 1 0 1 1 1 1 Basic region leucine zipper DUF812 PF05667.11 KFH46329.1 - 0.0033 16.4 3.7 0.0058 15.6 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SlyX PF04102.12 KFH46329.1 - 0.021 15.5 0.8 0.056 14.1 0.8 1.7 1 0 0 1 1 1 0 SlyX Cluap1 PF10234.9 KFH46329.1 - 0.029 13.8 6.0 0.05 13.0 6.0 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 SHE3 PF17078.5 KFH46329.1 - 0.04 13.6 6.3 0.093 12.4 6.3 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF2935 PF11155.8 KFH46329.1 - 0.059 13.7 2.7 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) dsrm PF00035.26 KFH46329.1 - 0.091 13.5 0.1 0.28 11.9 0.1 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif APG6_N PF17675.1 KFH46329.1 - 0.11 13.1 6.9 0.24 11.9 6.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region JIP_LZII PF16471.5 KFH46329.1 - 0.17 12.0 2.3 0.45 10.7 2.3 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Prefoldin PF02996.17 KFH46329.1 - 0.21 11.5 4.0 0.35 10.8 4.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit TMPIT PF07851.13 KFH46329.1 - 0.3 10.3 2.6 2.2 7.4 2.8 1.9 2 0 0 2 2 2 0 TMPIT-like protein TolA_bind_tri PF16331.5 KFH46329.1 - 0.37 10.9 5.1 1.1 9.4 5.1 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 KFH46329.1 - 0.38 10.8 7.7 0.78 9.8 7.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 KFH46329.1 - 0.63 10.3 6.5 1.5 9.1 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 KFH46329.1 - 0.65 10.1 6.8 0.73 9.9 5.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2730 PF10805.8 KFH46329.1 - 0.68 10.1 2.2 1.2 9.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ZapB PF06005.12 KFH46329.1 - 0.7 10.4 7.5 0.73 10.3 6.1 1.7 1 1 0 1 1 1 0 Cell division protein ZapB T3SSipB PF16535.5 KFH46329.1 - 1.4 9.3 8.3 0.29 11.6 4.3 1.8 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF4446 PF14584.6 KFH46329.1 - 3.3 7.7 4.3 6.5 6.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CENP-H PF05837.12 KFH46329.1 - 4.6 7.7 7.0 11 6.4 7.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) MFS_1 PF07690.16 KFH46330.1 - 7.4e-37 127.1 40.3 2.8e-36 125.2 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46330.1 - 4.3e-12 45.6 6.6 4.3e-12 45.6 6.6 3.0 3 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFH46330.1 - 1e-05 24.2 2.2 1e-05 24.2 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFH46330.1 - 0.0061 15.0 0.8 0.0061 15.0 0.8 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector RPN7 PF10602.9 KFH46331.1 - 6.7e-57 192.0 0.5 1.5e-56 190.9 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KFH46331.1 - 2e-15 57.2 0.0 4.6e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Cellulase PF00150.18 KFH46332.1 - 2.2e-30 106.0 1.6 1.6e-15 57.3 0.2 2.4 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Methyltransf_16 PF10294.9 KFH46333.1 - 1.9e-12 47.3 0.0 5e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KFH46333.1 - 0.0025 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFH46333.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFH46333.1 - 0.13 13.0 0.0 7.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HAD_2 PF13419.6 KFH46333.1 - 0.23 11.5 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glyco_hydro_3 PF00933.21 KFH46334.1 - 1.8e-62 211.6 0.0 2.6e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KFH46334.1 - 2.6e-05 24.4 0.0 0.00018 21.7 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KFH46334.1 - 0.0031 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.7 KFH46334.1 - 0.0047 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFH46334.1 - 0.035 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 KFH46335.1 - 2.2e-40 138.2 0.1 3.3e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46335.1 - 7e-40 137.0 1.3 1.2e-33 116.7 0.4 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH46335.1 - 8.1e-13 48.7 0.7 1.9e-12 47.4 0.7 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH46335.1 - 0.00012 21.6 0.2 0.0011 18.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFH46335.1 - 0.0071 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) IMS_C PF11799.8 KFH46335.1 - 0.16 12.6 0.0 0.62 10.8 0.0 1.8 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain ETF_QO PF05187.13 KFH46337.1 - 4.6e-48 161.7 0.6 7.3e-48 161.0 0.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KFH46337.1 - 1.4e-07 31.5 0.5 6.2e-05 22.7 0.2 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH46337.1 - 1.9e-07 31.2 0.0 5.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH46337.1 - 4.1e-05 23.0 0.0 0.00015 21.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH46337.1 - 8.2e-05 21.9 1.2 0.0031 16.7 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFH46337.1 - 0.0003 20.1 0.0 0.00076 18.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KFH46337.1 - 0.00043 20.8 0.1 0.9 10.1 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH46337.1 - 0.00065 19.0 0.2 0.0011 18.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFH46337.1 - 0.00091 18.0 0.6 0.0014 17.4 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KFH46337.1 - 0.0012 18.9 0.3 0.0056 16.7 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFH46337.1 - 0.0016 17.4 0.0 0.24 10.2 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KFH46337.1 - 0.0054 16.0 0.2 0.0079 15.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH46337.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 KFH46337.1 - 0.018 15.6 1.3 0.05 14.2 1.3 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KFH46337.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFH46337.1 - 0.071 12.1 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 KFH46337.1 - 0.15 12.2 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 KFH46337.1 - 0.19 10.7 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ESCRT-II PF05871.12 KFH46338.1 - 2.1e-52 177.1 0.0 2.7e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit GHMP_kinases_C PF08544.13 KFH46338.1 - 0.036 14.4 0.5 0.1 13.0 0.5 1.8 1 1 0 1 1 1 0 GHMP kinases C terminal TANGO2 PF05742.12 KFH46339.1 - 3e-61 207.7 0.0 3.5e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 K_channel_TID PF07941.11 KFH46339.1 - 1.3 9.6 7.8 3 8.3 7.8 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-RING_2 PF13639.6 KFH46340.1 - 1.4e-08 34.9 6.2 2.1e-08 34.3 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFH46340.1 - 2.4e-07 31.0 5.4 5.6e-07 29.8 5.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFH46340.1 - 2.1e-05 24.5 3.1 4.8e-05 23.3 3.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFH46340.1 - 0.0042 16.9 4.9 0.0098 15.7 4.6 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH46340.1 - 0.0056 16.5 5.9 0.015 15.1 5.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH46340.1 - 0.016 14.9 1.6 0.016 14.9 1.6 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KFH46340.1 - 0.039 13.8 2.4 0.083 12.7 0.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KFH46340.1 - 0.047 13.6 4.0 0.081 12.8 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH46340.1 - 0.15 12.1 3.0 0.16 12.0 1.6 1.8 1 1 1 2 2 2 0 RING-type zinc-finger Tmpp129 PF10272.9 KFH46340.1 - 0.75 9.0 4.1 1.1 8.5 4.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-UDP PF14569.6 KFH46340.1 - 0.77 9.9 4.4 1.6 8.9 4.4 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger DAO PF01266.24 KFH46341.1 - 2.1e-31 109.8 1.3 2.5e-31 109.5 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFH46341.1 - 5.6e-05 23.2 0.1 0.06 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFH46341.1 - 6.9e-05 23.0 0.0 0.00032 20.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFH46341.1 - 0.00052 19.2 0.0 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFH46341.1 - 0.011 14.8 0.1 4.3 6.3 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.14 KFH46341.1 - 0.031 13.5 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KFH46341.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 KFH46342.1 - 4.3e-37 127.9 56.6 3e-36 125.1 56.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH46342.1 - 3.4e-13 48.9 24.1 1.2e-12 47.1 24.0 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hexokinase_2 PF03727.16 KFH46343.1 - 4.2e-52 177.0 0.0 6.1e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFH46343.1 - 4e-37 128.1 0.0 8.8e-24 84.5 0.0 2.5 3 0 0 3 3 3 2 Hexokinase Methyltransf_16 PF10294.9 KFH46344.1 - 1.3e-25 90.1 0.0 3e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFH46344.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFH46344.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KFH46344.1 - 0.14 13.0 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Grg1 PF11034.8 KFH46345.1 - 2.4e-31 107.8 7.8 2.7e-31 107.6 7.8 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 F-actin_cap_A PF01267.17 KFH46346.1 - 1.4e-90 303.3 0.0 3.9e-89 298.6 0.0 2.0 1 1 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 KFH46346.1 - 0.077 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus DUF2014 PF09427.10 KFH46347.1 - 1.8e-101 338.9 8.3 2.6e-101 338.4 8.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KFH46347.1 - 1.2e-17 63.5 1.0 3.8e-17 62.0 1.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.14 KFH46347.1 - 0.0078 16.6 6.0 0.051 14.0 1.7 3.3 2 1 1 3 3 3 1 Nnf1 FAM76 PF16046.5 KFH46347.1 - 0.13 11.6 6.6 0.2 11.0 6.6 1.2 1 0 0 1 1 1 0 FAM76 protein Spt5_N PF11942.8 KFH46347.1 - 0.54 11.3 4.3 1.7 9.6 4.3 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CCDC106 PF15794.5 KFH46347.1 - 0.68 9.6 4.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Abhydrolase_6 PF12697.7 KFH46349.1 - 3.4e-12 47.4 13.5 6.7e-12 46.5 13.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH46349.1 - 1.7e-07 30.7 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFH46349.1 - 0.017 13.7 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KFH46349.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold TFA2_Winged_2 PF18121.1 KFH46350.1 - 2.1e-22 78.6 0.1 4e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KFH46350.1 - 7.9e-15 54.9 0.0 2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain Glyco_hydro_3 PF00933.21 KFH46351.1 - 3.7e-59 200.7 0.0 5.5e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KFH46351.1 - 1.7e-49 168.5 0.1 3.1e-49 167.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFH46351.1 - 3.7e-19 68.6 2.0 3.7e-19 68.6 2.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KFH46351.1 - 0.029 13.5 0.1 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative sugar-binding domain DUF11 PF01345.18 KFH46351.1 - 0.049 13.9 0.4 0.17 12.2 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF11 WGG PF10273.9 KFH46352.1 - 7.5e-36 122.7 0.3 1.4e-35 121.8 0.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KFH46352.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.3 1 1 2 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain P5CR_dimer PF14748.6 KFH46352.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Orthopox_A5L PF06193.11 KFH46353.1 - 0.01 15.3 0.4 0.023 14.1 0.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like TelA PF05816.11 KFH46353.1 - 0.029 13.4 6.1 0.048 12.7 6.1 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Prominin PF05478.11 KFH46353.1 - 0.42 8.5 3.4 0.58 8.0 3.4 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 KFH46353.1 - 5.7 5.4 5.0 8.9 4.8 5.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FUSC PF04632.12 KFH46353.1 - 5.8 5.3 6.9 10 4.5 6.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KFH46353.1 - 7.7 5.8 9.1 16 4.8 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 KFH46354.1 - 1.8e-06 28.1 12.3 0.00024 21.4 4.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH46354.1 - 4.6e-06 26.8 0.8 4.6e-06 26.8 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH46354.1 - 0.0016 19.1 8.8 0.02 15.7 2.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFH46354.1 - 0.99 9.9 3.4 1.1 9.7 0.7 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PEMT PF04191.13 KFH46355.1 - 3.2e-32 111.1 2.9 5.7e-32 110.3 2.9 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KFH46355.1 - 0.11 12.5 0.7 0.21 11.6 0.7 1.6 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Thiolase_N PF00108.23 KFH46356.1 - 3.1e-69 233.2 1.1 4.2e-69 232.8 1.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH46356.1 - 1.4e-41 141.0 1.1 2.2e-41 140.4 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFH46356.1 - 0.032 13.8 5.0 0.047 13.3 3.1 2.2 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFH46356.1 - 0.17 11.8 3.7 1.2 9.0 0.3 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 4HBT PF03061.22 KFH46357.1 - 2.7e-15 56.5 0.0 3.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFH46357.1 - 0.04 14.2 0.0 0.047 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 KFH46357.1 - 0.062 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) LapA_dom PF06305.11 KFH46358.1 - 0.0064 16.3 0.8 0.0097 15.7 0.8 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain SP_C-Propep PF08999.10 KFH46358.1 - 0.011 15.5 2.9 0.1 12.4 1.1 2.1 1 1 1 2 2 2 0 Surfactant protein C, N terminal propeptide DUF3112 PF11309.8 KFH46358.1 - 0.037 13.5 0.2 0.049 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Zn_peptidase PF04228.13 KFH46358.1 - 0.071 12.5 0.1 0.089 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase CBP_BcsF PF11120.8 KFH46358.1 - 0.098 12.8 0.4 0.15 12.2 0.4 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF DUF945 PF06097.11 KFH46358.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Insulin_TMD PF17870.1 KFH46358.1 - 0.12 12.5 2.1 0.19 11.8 2.1 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HemY_N PF07219.13 KFH46358.1 - 0.12 12.6 0.6 0.17 12.1 0.6 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF819 PF05684.12 KFH46358.1 - 0.3 10.1 4.1 0.39 9.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Ribosomal_S7 PF00177.21 KFH46361.1 - 4.9e-25 87.9 0.0 7.2e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-RRN7 PF11781.8 KFH46361.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 BSD PF03909.17 KFH46362.1 - 7.5e-21 73.9 0.1 1.5e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 BSD domain SOG2 PF10428.9 KFH46362.1 - 0.52 9.4 0.0 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein RRM_1 PF00076.22 KFH46363.1 - 1.4e-83 274.7 6.8 2e-22 78.8 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFH46363.1 - 3.5e-25 88.0 1.7 1.6e-24 85.9 1.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KFH46363.1 - 2.6e-10 39.9 0.0 0.046 13.3 0.0 5.1 2 1 2 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH46363.1 - 1.6e-08 34.3 0.0 6e-06 26.0 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KFH46363.1 - 1.1e-06 28.7 0.5 0.43 10.7 0.0 5.5 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFH46363.1 - 1.6e-05 24.8 0.1 6.5 6.8 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KFH46363.1 - 0.016 15.7 5.7 0.073 13.6 0.5 3.3 3 0 0 3 3 3 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 KFH46363.1 - 0.016 15.3 0.9 6.4 6.9 0.1 3.4 3 0 0 3 3 3 0 Limkain b1 CbiG_mid PF11761.8 KFH46363.1 - 0.036 14.2 0.0 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis central region DHHA1 PF02272.19 KFH46363.1 - 0.052 14.0 6.5 0.8 10.1 0.1 3.3 3 0 0 3 3 3 0 DHHA1 domain OB_RNB PF08206.11 KFH46363.1 - 0.058 13.1 1.7 9 6.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain NPR3 PF03666.13 KFH46363.1 - 0.16 10.7 5.3 0.26 10.0 5.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 KFH46363.1 - 0.22 9.6 15.8 0.33 9.0 15.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFH46363.1 - 0.38 9.0 13.7 0.55 8.5 13.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFH46363.1 - 3.8 6.2 6.4 5.3 5.7 6.4 1.2 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 KFH46363.1 - 3.8 7.6 11.9 11 6.1 11.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) F-box-like PF12937.7 KFH46364.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Ceramidase_alk PF04734.13 KFH46365.1 - 2.9e-211 702.5 0.0 3.3e-211 702.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFH46365.1 - 1.3e-57 194.3 0.2 2e-57 193.7 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Cellulase PF00150.18 KFH46366.1 - 6e-10 39.0 0.0 6e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.6 KFH46366.1 - 0.026 15.4 0.0 0.026 15.4 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFH46366.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 KFH46366.1 - 0.052 13.5 0.5 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2371 PF10177.9 KFH46366.1 - 0.17 12.0 1.4 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Glycophorin_A PF01102.18 KFH46366.1 - 0.19 12.0 0.7 0.5 10.6 0.7 1.6 1 0 0 1 1 1 0 Glycophorin A Med13_C PF06333.12 KFH46367.1 - 5.2e-92 308.6 4.5 5.2e-92 308.6 4.5 2.4 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KFH46367.1 - 1.8e-29 103.1 0.3 5.2e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KFH46367.1 - 1.2e-07 31.8 6.6 0.00023 21.0 0.0 3.4 4 0 0 4 4 4 2 MID domain of medPIWI UvrD-helicase PF00580.21 KFH46368.1 - 2.4e-67 227.7 0.1 1.2e-64 218.8 0.0 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KFH46368.1 - 8e-64 216.2 0.2 6.5e-63 213.2 0.1 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFH46368.1 - 1.6e-31 109.6 0.0 4.9e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KFH46368.1 - 1.3e-14 53.7 0.0 3.7e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KFH46368.1 - 1e-09 38.4 0.2 2e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFH46368.1 - 1.3e-05 25.1 0.2 0.66 9.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KFH46368.1 - 0.0001 22.0 0.2 0.00096 18.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH46368.1 - 0.033 14.6 0.3 2.2 8.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_11 PF13086.6 KFH46368.1 - 0.18 11.6 4.2 0.25 11.1 0.6 2.9 2 1 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KFH46369.1 - 5.8e-76 254.6 54.5 1.5e-40 138.9 17.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFH46369.1 - 2.9e-36 125.0 0.0 2.3e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFH46369.1 - 2.6e-27 94.5 0.8 1.5e-23 82.5 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFH46369.1 - 3.4e-14 53.2 0.0 1.4e-13 51.2 0.0 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_17 PF13207.6 KFH46369.1 - 1.6e-07 31.8 0.0 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFH46369.1 - 2e-07 31.3 0.0 0.00062 19.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFH46369.1 - 3.1e-07 30.9 0.9 0.00092 19.6 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KFH46369.1 - 6e-06 26.3 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFH46369.1 - 7.6e-06 26.5 0.0 0.0092 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFH46369.1 - 0.00012 21.7 0.1 0.011 15.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFH46369.1 - 0.00033 20.3 0.1 0.0046 16.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFH46369.1 - 0.0004 20.3 0.1 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KFH46369.1 - 0.00083 19.6 0.0 0.043 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH46369.1 - 0.0016 18.7 0.0 0.56 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KFH46369.1 - 0.0019 17.4 10.4 0.0019 17.4 10.4 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.19 KFH46369.1 - 0.0031 17.1 1.6 0.14 11.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFH46369.1 - 0.0038 17.1 0.2 3.4 7.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 KFH46369.1 - 0.0041 16.6 0.0 0.69 9.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFH46369.1 - 0.065 13.0 0.2 3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFH46369.1 - 0.072 12.8 0.3 11 5.8 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KFH46369.1 - 0.075 13.5 0.2 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH46369.1 - 0.085 13.2 0.1 9.3 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KFH46369.1 - 0.11 12.5 0.7 7.3 6.6 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KFH46369.1 - 0.11 12.9 0.0 24 5.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFH46369.1 - 0.13 12.0 1.0 15 5.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain Wzz PF02706.15 KFH46369.1 - 5.6 7.3 6.1 6.4 7.2 0.2 3.3 3 0 0 3 3 2 0 Chain length determinant protein Gryzun PF07919.12 KFH46370.1 - 1.1e-226 754.2 0.0 1.4e-226 753.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KFH46370.1 - 8.5e-88 294.3 0.6 2.4e-83 279.7 0.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KFH46370.1 - 0.00077 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Surp PF01805.20 KFH46371.1 - 2.8e-08 33.6 0.0 5.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Surp module Fungal_trans PF04082.18 KFH46372.1 - 2.3e-10 40.0 0.2 7.4e-10 38.3 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFH46372.1 - 1.6e-06 28.2 14.2 0.005 17.2 0.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH46372.1 - 4.4e-06 26.9 15.6 2.4e-05 24.6 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH46372.1 - 1.5e-05 25.4 9.4 0.012 16.4 2.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH46372.1 - 0.093 13.0 0.4 0.76 10.1 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFH46372.1 - 7.8 6.5 6.6 4.8 7.2 2.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Pex14_N PF04695.13 KFH46372.1 - 10 6.8 15.5 9.9 6.8 8.6 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glucosamine_iso PF01182.20 KFH46373.1 - 3.3e-22 79.5 0.0 5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Abhydrolase_3 PF07859.13 KFH46374.1 - 8.8e-40 136.8 0.1 4.4e-30 105.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH46374.1 - 4.3e-11 42.3 0.0 4.6e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KFH46374.1 - 0.0022 16.9 1.3 0.019 13.8 1.3 2.1 1 1 0 1 1 1 1 Carboxylesterase family Kisspeptin PF15152.6 KFH46374.1 - 0.0073 17.1 0.3 5.5 7.8 0.2 3.0 2 0 0 2 2 2 2 Kisspeptin Hydrolase_4 PF12146.8 KFH46374.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Epimerase PF01370.21 KFH46375.1 - 5.2e-10 39.2 0.1 1.2e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFH46375.1 - 1.3e-09 38.2 0.2 2e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFH46375.1 - 0.00026 20.6 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.10 KFH46375.1 - 0.00033 20.2 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 HIM1 DUF1471 PF07338.13 KFH46375.1 - 0.0031 17.4 0.8 0.0075 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1471) Semialdhyde_dh PF01118.24 KFH46375.1 - 0.03 14.8 0.0 0.078 13.4 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFH46375.1 - 0.1 11.7 0.0 2.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Male sterility protein Amidohydro_1 PF01979.20 KFH46377.1 - 9.4e-12 44.9 0.0 4e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH46377.1 - 1.3e-11 44.7 0.1 8.2e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Flavokinase PF01687.17 KFH46378.1 - 7.3e-32 110.0 0.0 1.5e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 KFH46379.1 - 0.00057 19.9 0.0 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 KFH46379.1 - 0.0033 17.5 8.6 0.0033 17.5 8.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_125 PF06824.11 KFH46380.1 - 3.1e-180 599.5 0.0 3.6e-180 599.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Pyr_redox_2 PF07992.14 KFH46381.1 - 1.9e-45 155.4 0.2 2.7e-45 154.9 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KFH46381.1 - 2e-19 69.6 0.0 5.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KFH46381.1 - 2e-16 60.3 1.4 2.9e-14 53.4 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KFH46381.1 - 3.1e-13 49.6 0.0 2.7e-12 46.5 0.0 2.5 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 KFH46381.1 - 1.1e-12 48.1 9.0 9.3e-11 41.9 4.8 3.0 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KFH46381.1 - 1.4e-11 44.1 0.1 8.9e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KFH46381.1 - 7.1e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 KFH46381.1 - 6.6e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KFH46381.1 - 0.00011 22.0 0.0 0.73 9.8 0.0 3.4 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KFH46381.1 - 0.026 14.5 2.0 6.7 6.7 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFH46381.1 - 0.026 13.8 0.2 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KFH46381.1 - 0.12 12.8 0.2 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KFH46381.1 - 0.22 10.6 0.8 1.8 7.6 0.0 2.5 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 KFH46381.1 - 0.61 9.1 1.5 25 3.8 0.2 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A TBP PF00352.21 KFH46383.1 - 1.4e-67 223.6 0.1 6.9e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFH46383.1 - 0.00011 22.3 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KFH46383.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DUF1990 PF09348.10 KFH46384.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) RTT107_BRCT_5 PF16770.5 KFH46385.1 - 1.2e-32 111.7 0.0 6.9e-31 106.1 0.0 3.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFH46385.1 - 1e-26 92.6 0.5 3.1e-18 65.5 0.2 4.7 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KFH46385.1 - 7.4e-26 90.3 0.0 2.2e-08 34.3 0.0 5.8 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFH46385.1 - 4.2e-22 78.4 0.0 4.6e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFH46385.1 - 1e-07 32.1 0.8 0.14 12.4 0.0 3.9 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KFH46385.1 - 0.0019 18.3 0.1 0.76 9.9 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain MRP-L27 PF09809.9 KFH46386.1 - 6e-07 29.3 0.2 7.7e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cyt-b5 PF00173.28 KFH46388.1 - 3.4e-24 84.8 0.2 4.5e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U62_UL91 PF17442.2 KFH46388.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins Glyco_hydro_31 PF01055.26 KFH46390.1 - 2.4e-110 369.8 0.4 2.9e-110 369.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFH46390.1 - 1.1e-16 60.9 1.7 2.9e-16 59.6 0.2 2.4 3 0 0 3 3 3 1 Galactose mutarotase-like Aminotran_1_2 PF00155.21 KFH46391.1 - 3.6e-38 131.7 0.0 4.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Piwi PF02171.17 KFH46392.1 - 2.6e-67 227.2 0.0 4.2e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFH46392.1 - 3.3e-12 47.2 0.1 5.8e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFH46392.1 - 2.7e-09 36.6 0.0 7e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFH46392.1 - 6.6e-06 26.4 0.0 2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KFH46392.1 - 5.2e-05 23.1 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain HEAT PF02985.22 KFH46392.1 - 0.043 14.1 0.3 0.24 11.8 0.0 2.4 3 0 0 3 3 3 0 HEAT repeat DSBA PF01323.20 KFH46393.1 - 5.3e-22 78.5 0.0 6.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KFH46393.1 - 0.014 15.4 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain PLDc_2 PF13091.6 KFH46394.1 - 7.8e-20 71.1 0.0 1.3e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFH46394.1 - 6e-06 26.2 0.0 0.0045 17.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KFH46394.1 - 0.051 12.8 0.0 0.18 11.0 0.0 1.9 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Pribosyltran PF00156.27 KFH46394.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain VHS PF00790.19 KFH46395.1 - 2.9e-21 75.8 0.0 7.6e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KFH46395.1 - 1.4e-07 31.7 1.8 3.3e-07 30.5 1.8 1.6 1 0 0 1 1 1 1 GAT domain RTX PF02382.15 KFH46395.1 - 0.0099 15.6 1.0 0.015 15.0 1.0 1.2 1 0 0 1 1 1 1 N-terminal domain in RTX protein Period_C PF12114.8 KFH46395.1 - 0.011 15.4 4.5 0.017 14.7 4.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.9 KFH46395.1 - 0.15 11.7 18.3 0.26 10.9 18.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 KFH46395.1 - 3.2 6.1 12.6 4.3 5.7 12.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 COX16 PF14138.6 KFH46395.1 - 7.9 7.1 8.7 3.5 8.2 0.2 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Polysacc_synt PF01943.17 KFH46396.1 - 0.16 11.4 4.6 3.4 7.0 0.8 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2919 PF11143.8 KFH46396.1 - 1.2 9.4 5.3 3.4 8.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) Amastin PF07344.11 KFH46396.1 - 3.7 7.4 12.4 1.1 9.1 0.6 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein RXT2_N PF08595.11 KFH46397.1 - 4.9e-47 159.8 0.0 4.9e-47 159.8 0.0 2.7 3 0 0 3 3 3 1 RXT2-like, N-terminal DinB_2 PF12867.7 KFH46397.1 - 0.28 11.7 1.8 3.6 8.1 0.1 2.7 2 1 1 3 3 3 0 DinB superfamily PRiA4_ORF3 PF07929.11 KFH46398.1 - 0.09 12.5 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein Tfb2 PF03849.14 KFH46399.1 - 7.9e-136 452.7 0.0 9.6e-136 452.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KFH46399.1 - 8.7e-21 74.1 0.5 1.8e-20 73.1 0.5 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KFH46399.1 - 0.00017 21.7 0.2 0.00049 20.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NUC153 PF08159.12 KFH46400.1 - 8.5e-14 51.1 1.5 1.9e-13 50.0 1.5 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFH46400.1 - 0.00048 20.9 0.4 29 5.8 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Usp PF00582.26 KFH46401.1 - 2.3e-22 80.0 6.1 8.3e-22 78.2 2.7 2.7 2 1 0 2 2 2 1 Universal stress protein family PdxJ PF03740.13 KFH46401.1 - 0.098 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ DUF3632 PF12311.8 KFH46402.1 - 1.4e-36 126.5 5.8 2.4e-36 125.8 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) APH PF01636.23 KFH46402.1 - 2.4e-09 37.5 0.0 6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fez1 PF06818.15 KFH46403.1 - 0.2 12.1 65.8 0.25 11.8 26.1 4.2 2 2 3 5 5 5 0 Fez1 CALCOCO1 PF07888.11 KFH46403.1 - 2.3 7.0 65.7 1.2 7.9 14.2 2.9 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 KFH46403.1 - 9.9 6.2 22.0 1.8 8.6 2.0 5.1 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nop14 PF04147.12 KFH46404.1 - 0.075 11.2 29.7 0.1 10.8 29.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 KFH46404.1 - 0.14 11.5 21.2 0.26 10.6 21.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 KFH46404.1 - 0.19 11.1 34.0 0.27 10.6 34.0 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 KFH46404.1 - 2.9 7.8 8.2 6.1 6.7 8.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Mpp10 PF04006.12 KFH46404.1 - 5.1 5.4 25.0 6.8 5.0 25.0 1.1 1 0 0 1 1 1 0 Mpp10 protein VIR_N PF15912.5 KFH46404.1 - 5.9 6.4 31.1 11 5.5 31.1 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal PPP4R2 PF09184.11 KFH46404.1 - 6.5 6.3 25.6 12 5.3 25.6 1.5 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KFH46404.1 - 8.7 5.6 37.0 8.5 5.6 35.9 1.5 2 0 0 2 2 2 0 BUD22 C2 PF00168.30 KFH46405.1 - 9e-22 77.3 0.0 8e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain Phage_holin_3_6 PF07332.11 KFH46405.1 - 0.12 12.4 0.7 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III XRCC4 PF06632.12 KFH46406.1 - 0.26 10.1 2.8 0.4 9.5 2.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TFIIA PF03153.13 KFH46406.1 - 1.4 8.9 8.8 1.9 8.4 8.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 KFH46406.1 - 7.2 5.3 9.1 5.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zinc_ribbon_15 PF17032.5 KFH46407.1 - 4.9e-05 24.0 0.5 7.4e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon family PriA_CRR PF18319.1 KFH46407.1 - 0.14 12.2 9.9 2 8.5 0.1 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain UQ_con PF00179.26 KFH46408.1 - 4.5e-50 169.0 0.0 5.3e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH46408.1 - 1.3e-05 25.0 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFH46408.1 - 0.00069 19.9 0.0 0.00083 19.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFH46408.1 - 0.0043 16.9 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Glyco_transf_28 PF03033.20 KFH46409.1 - 3.3e-19 69.3 0.6 3.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFH46409.1 - 4.5e-05 22.4 0.0 7.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 KFH46409.1 - 0.0015 18.3 34.8 0.099 12.6 3.6 5.2 5 0 0 5 5 5 4 Ubiquitin interaction motif Glyco_tran_28_C PF04101.16 KFH46409.1 - 0.012 15.7 0.3 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KFH46409.1 - 0.024 15.0 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Phage_holin_6_1 PF09682.10 KFH46409.1 - 3.1 8.3 3.8 2.2 8.8 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Methyltransf_25 PF13649.6 KFH46410.1 - 1.3e-16 61.1 0.0 4.7e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46410.1 - 1.4e-13 51.3 0.2 5.7e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46410.1 - 4.8e-13 49.2 0.0 6.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46410.1 - 1.7e-10 41.5 0.0 3.5e-10 40.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH46410.1 - 5.8e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH46410.1 - 5.3e-06 26.1 0.0 8.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFH46410.1 - 6e-06 26.2 0.0 9.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KFH46410.1 - 0.00016 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KFH46410.1 - 0.00033 20.1 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KFH46410.1 - 0.006 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KFH46410.1 - 0.0066 15.8 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFH46410.1 - 0.0096 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KFH46410.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MRF_C1 PF13887.6 KFH46410.1 - 0.021 14.0 0.1 1 8.6 0.1 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 zf-ANAPC11 PF12861.7 KFH46411.1 - 3.3e-45 152.1 12.0 3.8e-45 151.9 12.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFH46411.1 - 2.5e-21 75.7 11.3 3.7e-21 75.2 11.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFH46411.1 - 6.6e-08 32.8 16.6 2.6e-06 27.7 16.6 2.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH46411.1 - 3.2e-06 27.1 7.0 4.7e-05 23.3 4.1 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFH46411.1 - 8.2e-05 22.4 14.1 0.00032 20.5 14.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH46411.1 - 9e-05 22.2 4.2 9e-05 22.2 4.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFH46411.1 - 0.0014 18.3 13.0 0.094 12.5 10.2 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFH46411.1 - 0.0023 18.0 15.4 0.033 14.3 15.4 2.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KFH46411.1 - 0.0024 17.7 13.9 0.15 12.0 13.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFH46411.1 - 0.0034 17.0 12.0 0.045 13.4 12.0 2.2 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KFH46411.1 - 0.0092 15.8 5.3 0.015 15.1 5.3 1.4 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFH46411.1 - 0.012 15.8 9.3 0.012 15.8 9.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 KFH46411.1 - 0.017 15.0 3.2 0.039 13.8 0.8 2.3 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 KFH46411.1 - 0.038 13.8 3.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KFH46411.1 - 0.13 12.0 12.7 0.65 9.8 9.7 2.9 2 1 0 2 2 2 0 RING-like zinc finger YacG PF03884.14 KFH46411.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Zn-C2H2_12 PF18112.1 KFH46411.1 - 0.29 11.6 6.5 0.86 10.1 0.1 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_5 PF14634.6 KFH46411.1 - 0.3 11.1 17.5 10 6.2 17.9 2.7 1 1 1 2 2 2 0 zinc-RING finger domain DUF2256 PF10013.9 KFH46411.1 - 0.61 10.3 0.2 0.61 10.3 0.2 3.6 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) UBZ_FAAP20 PF15750.5 KFH46411.1 - 1.3 9.0 6.3 2.6 8.1 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zf-C2H2_9 PF16293.5 KFH46411.1 - 1.8 8.5 5.6 26 4.8 0.0 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING-like PF08746.11 KFH46411.1 - 3.7 7.9 14.0 25 5.3 14.0 2.3 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFH46411.1 - 4.6 7.4 15.6 2.9 8.1 12.3 2.3 1 1 1 2 2 2 0 RING-variant domain PHD PF00628.29 KFH46411.1 - 4.6 7.2 14.3 21 5.1 14.3 2.0 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 KFH46411.1 - 6.7 6.8 13.6 4.7 7.3 6.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Asp PF00026.23 KFH46412.1 - 4.4e-55 187.3 0.0 6.1e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH46412.1 - 2e-10 41.2 0.7 4.5e-06 27.0 0.6 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFH46412.1 - 0.0041 17.7 0.1 4.7 7.9 0.0 3.3 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 KFH46412.1 - 0.0059 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.18 KFH46413.1 - 1.3e-53 181.0 0.1 1.6e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase E1-E2_ATPase PF00122.20 KFH46414.1 - 1.7e-50 171.0 0.7 5e-50 169.5 0.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KFH46414.1 - 1.5e-46 156.6 0.5 3.2e-12 46.7 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KFH46414.1 - 3e-36 125.7 3.9 3e-36 125.7 3.9 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFH46414.1 - 6.4e-06 26.1 1.4 2.3e-05 24.2 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2089 PF09862.9 KFH46414.1 - 0.22 11.6 0.1 34 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) Rho_N PF07498.12 KFH46416.1 - 0.17 11.8 0.3 0.26 11.2 0.3 1.2 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain RGS PF00615.19 KFH46417.1 - 8.9e-11 42.1 0.0 3.7e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_S8 PF00410.19 KFH46418.1 - 2.5e-12 46.9 0.0 4.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein S8 Aldo_ket_red PF00248.21 KFH46419.1 - 4e-45 154.2 0.0 5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1776 PF08643.10 KFH46420.1 - 2e-101 339.3 0.0 2.5e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KFH46420.1 - 0.15 11.5 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Cation_efflux PF01545.21 KFH46421.1 - 4e-51 173.6 8.7 1.9e-50 171.4 8.7 1.8 1 1 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KFH46421.1 - 2.4 7.2 9.9 0.038 13.2 1.4 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Memo PF01875.17 KFH46423.1 - 2.8e-68 230.0 0.0 3.2e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Fungal_trans PF04082.18 KFH46424.1 - 7.5e-14 51.4 0.1 1.3e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46424.1 - 2.4e-05 24.3 7.9 4.2e-05 23.6 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.16 KFH46425.1 - 1.4e-31 109.9 15.6 1.7e-31 109.7 15.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFH46425.1 - 3.7e-06 26.4 17.2 9.4e-06 25.0 17.2 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFH46425.1 - 0.045 13.9 34.9 0.019 15.1 11.0 2.3 2 0 0 2 2 2 0 EamA-like transporter family Aldose_epim PF01263.20 KFH46427.1 - 1.3e-40 139.6 0.0 1.5e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase WD40 PF00400.32 KFH46428.1 - 2.3e-33 113.7 7.1 4.4e-07 30.5 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH46428.1 - 1.7e-13 50.7 0.1 9.5e-06 25.8 0.0 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 KFH46429.1 - 8e-13 48.6 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46429.1 - 0.00017 22.1 0.0 0.0015 19.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46429.1 - 0.00023 21.8 0.0 0.0014 19.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH46429.1 - 0.011 16.4 0.0 0.06 14.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46429.1 - 0.037 13.8 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Rif1_N PF12231.8 KFH46430.1 - 7.2e-144 479.4 0.7 1e-143 478.9 0.7 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal FMN_red PF03358.15 KFH46431.1 - 6.1e-10 39.1 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFH46431.1 - 5.2e-07 29.6 0.0 6.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFH46431.1 - 0.00013 22.2 0.2 0.0046 17.2 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin Acetyltransf_3 PF13302.7 KFH46433.1 - 1.1e-34 120.1 0.1 1.4e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH46433.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family F-box-like PF12937.7 KFH46434.1 - 0.074 13.0 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 F-box-like Raf1_N PF18578.1 KFH46434.1 - 0.092 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain Ribosomal_L18A PF01775.17 KFH46435.1 - 1.4e-53 180.1 0.3 1.9e-53 179.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF155 PF02582.14 KFH46436.1 - 1.6e-55 187.9 0.1 2.9e-55 187.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cyclin_N PF00134.23 KFH46438.1 - 3.2e-38 130.3 0.1 6.6e-38 129.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFH46438.1 - 9.3e-11 41.9 0.2 3.2e-10 40.1 0.2 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Caskin-Pro-rich PF16907.5 KFH46438.1 - 0.0034 17.9 0.1 0.0074 16.8 0.1 1.5 1 0 0 1 1 1 1 Proline rich region of Caskin proteins BTB PF00651.31 KFH46439.1 - 7.4e-08 32.6 0.2 2.9e-07 30.7 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain Ribosomal_60s PF00428.19 KFH46440.1 - 0.039 14.5 0.9 0.044 14.4 0.9 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein TilS PF09179.11 KFH46441.1 - 0.17 12.4 3.6 11 6.7 0.1 4.0 4 0 0 4 4 4 0 TilS substrate binding domain TrkH PF02386.16 KFH46442.1 - 6.5e-101 338.3 0.6 3.6e-97 325.9 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein Sulfatase PF00884.23 KFH46443.1 - 2e-58 198.2 0.1 2.7e-58 197.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KFH46443.1 - 8.9e-25 86.3 4.1 1e-24 86.0 0.7 2.7 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KFH46443.1 - 2e-09 37.5 0.3 3.9e-08 33.3 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFH46443.1 - 1.2e-05 24.2 0.0 2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KFH46443.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4976 PF16347.5 KFH46443.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) GFA PF04828.14 KFH46445.1 - 9.2e-12 45.2 3.9 5.7e-11 42.6 3.9 2.0 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 KFH46445.1 - 0.058 13.3 11.0 0.1 12.5 5.3 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Glyco_transf_90 PF05686.12 KFH46446.1 - 0.00036 19.5 0.3 0.62 8.9 0.1 3.8 3 2 0 3 3 3 2 Glycosyl transferase family 90 RNase_P_p30 PF01876.16 KFH46448.1 - 8.5e-56 188.8 0.0 1.9e-55 187.7 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit p30 FAD_binding_8 PF08022.12 KFH46449.1 - 1.7e-23 82.7 0.0 3.9e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFH46449.1 - 2e-21 76.7 0.0 3.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFH46449.1 - 3.6e-20 72.4 10.9 3.6e-20 72.4 10.9 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KFH46449.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SWIRM-assoc_2 PF16496.5 KFH46450.1 - 0.00099 18.1 0.3 0.00099 18.1 0.3 4.2 4 0 0 4 4 4 1 SWIRM-associated domain at the N-terminal DUF3438 PF11920.8 KFH46450.1 - 1.4 8.1 6.1 4 6.6 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Sec61_beta PF03911.16 KFH46451.1 - 2.2e-17 62.8 2.2 3.1e-17 62.3 2.2 1.2 1 0 0 1 1 1 1 Sec61beta family NrfD PF03916.14 KFH46452.1 - 0.21 11.2 5.6 0.081 12.5 1.7 1.7 1 1 1 2 2 2 0 Polysulphide reductase, NrfD Pkinase PF00069.25 KFH46453.1 - 7.8e-60 202.5 0.0 1.1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46453.1 - 4e-30 105.0 0.0 5.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH46453.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH46453.1 - 0.0086 16.0 0.0 0.77 9.6 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFH46453.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane_2 PF06472.15 KFH46454.1 - 1.6e-89 299.9 0.0 1.7e-88 296.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFH46454.1 - 8.6e-17 61.9 0.0 1.9e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFH46454.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFH46454.1 - 0.014 15.8 0.4 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KFH46454.1 - 0.051 12.9 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFH46454.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 KFH46454.1 - 0.09 13.3 1.1 0.91 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KFH46454.1 - 0.093 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KFH46454.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH46454.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Uds1 PF15456.6 KFH46454.1 - 0.7 10.1 3.3 0.48 10.6 1.4 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Amidase PF01425.21 KFH46455.1 - 5.8e-94 315.6 0.0 9.4e-94 314.9 0.0 1.3 1 1 0 1 1 1 1 Amidase Rhodanese PF00581.20 KFH46456.1 - 1.2e-18 67.6 0.0 1.2e-11 45.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Glyco_hydro_18 PF00704.28 KFH46457.1 - 8.5e-55 186.7 0.0 1.1e-54 186.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GTP_EFTU PF00009.27 KFH46458.1 - 4.2e-58 196.1 0.2 7.5e-58 195.3 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFH46458.1 - 3.1e-32 110.9 0.0 8e-32 109.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFH46458.1 - 1.3e-31 108.5 0.0 2.6e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFH46458.1 - 6.5e-22 77.4 0.0 1.6e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFH46458.1 - 1.4e-13 51.0 0.0 3.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFH46458.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KFH46458.1 - 0.015 15.7 0.0 0.41 11.1 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain FliT PF05400.13 KFH46458.1 - 0.036 14.9 0.3 0.098 13.5 0.3 1.8 1 0 0 1 1 1 0 Flagellar protein FliT MMR_HSR1 PF01926.23 KFH46458.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase CDT1_C PF16679.5 KFH46458.1 - 0.15 12.5 0.1 0.45 11.0 0.1 1.8 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Pkinase_Tyr PF07714.17 KFH46459.1 - 7.2e-06 25.5 0.1 0.0015 17.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFH46459.1 - 5.8e-05 22.6 0.0 0.00036 20.0 0.0 2.2 2 1 1 3 3 3 1 Protein kinase domain PCI PF01399.27 KFH46460.1 - 0.00012 22.6 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KFH46460.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Sigma70_r1_1 PF03979.14 KFH46460.1 - 0.027 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 zf-C2H2 PF00096.26 KFH46461.1 - 6.5e-05 23.2 15.2 0.083 13.4 2.0 4.3 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-TRAF PF02176.18 KFH46461.1 - 0.096 13.4 2.6 0.71 10.6 2.6 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_4 PF13894.6 KFH46461.1 - 0.35 11.8 21.5 0.21 12.5 1.7 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KFH46461.1 - 0.38 10.7 4.5 0.69 9.8 4.5 1.4 1 0 0 1 1 1 0 Seven in absentia protein family LRR_4 PF12799.7 KFH46462.1 - 6.3e-35 118.6 36.0 8.3e-09 35.6 1.7 6.7 2 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH46462.1 - 8.6e-24 83.1 21.6 2.8e-06 27.0 2.6 5.6 4 2 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KFH46462.1 - 1.9e-15 56.8 12.1 1.8e-06 27.6 0.8 4.6 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 KFH46462.1 - 3.8e-06 26.5 17.3 0.33 11.1 0.1 7.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 KFH46462.1 - 0.0041 17.5 21.4 3.8 8.4 0.4 7.9 8 1 0 8 8 8 2 Leucine Rich Repeat DUF1233 PF06806.12 KFH46462.1 - 0.2 11.3 0.2 1.9 8.1 0.0 2.7 3 1 0 3 3 3 0 Putative excisionase (DUF1233) Ribosomal_L31e PF01198.19 KFH46463.1 - 4e-42 142.4 1.1 5.4e-42 141.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 KFH46463.1 - 0.089 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel TrbC_Ftype PF09673.10 KFH46463.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein FAD_binding_3 PF01494.19 KFH46464.1 - 2.5e-16 59.9 0.0 5.8e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH46464.1 - 6.7e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH46464.1 - 0.00012 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFH46464.1 - 0.00059 19.0 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KFH46464.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH46464.1 - 0.0034 16.2 0.0 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 KFH46464.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.27 KFH46464.1 - 0.023 15.2 0.0 0.088 13.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH46464.1 - 0.079 12.3 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFH46464.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFH46464.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH PF00642.24 KFH46465.1 - 8.8e-26 89.3 33.9 2.7e-08 33.5 0.6 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFH46465.1 - 2.3e-21 75.1 35.9 4e-06 26.7 3.1 5.5 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KFH46465.1 - 1.6e-11 44.9 24.5 7.4e-05 23.4 0.5 5.4 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KFH46465.1 - 2.2e-09 36.9 45.3 9.9e-06 25.2 1.4 5.7 6 0 0 6 6 6 5 CCCH-type zinc finger DUF4637 PF15470.6 KFH46465.1 - 0.092 12.5 3.0 0.17 11.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-CCCH_3 PF15663.5 KFH46465.1 - 0.098 12.9 15.0 4.3 7.6 0.8 3.4 2 1 1 3 3 3 0 Zinc-finger containing family GRP PF07172.11 KFH46465.1 - 4.8 8.0 17.5 1.6 9.4 13.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family Iso_dh PF00180.20 KFH46466.1 - 5.5e-98 328.3 0.0 8.1e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sugar_tr PF00083.24 KFH46467.1 - 2.2e-115 386.1 13.9 2.7e-115 385.8 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46467.1 - 5.8e-20 71.5 25.9 2.1e-13 49.9 3.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFH46467.1 - 0.022 13.0 0.7 0.048 11.9 0.7 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Arginase PF00491.21 KFH46468.1 - 1.6e-68 231.3 0.0 3.5e-68 230.1 0.0 1.5 1 1 0 1 1 1 1 Arginase family HATPase_c PF02518.26 KFH46470.1 - 3.8e-28 98.2 0.1 7e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH46470.1 - 1e-22 80.4 0.0 2.2e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFH46470.1 - 8.6e-21 73.7 0.0 2.9e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KFH46470.1 - 6.6e-19 68.0 0.2 4.7e-18 65.3 0.2 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KFH46470.1 - 7e-13 48.7 0.0 2.2e-05 24.7 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 KFH46470.1 - 1.6e-11 44.5 2.6 1.2e-06 28.8 0.0 5.2 4 2 0 4 4 4 2 PAS fold PAS PF00989.25 KFH46470.1 - 5.2e-08 32.9 0.2 0.043 13.8 0.0 4.2 5 0 0 5 5 5 3 PAS fold PAS_8 PF13188.7 KFH46470.1 - 8.9e-05 22.4 0.1 1 9.4 0.1 3.7 3 0 0 3 3 3 2 PAS domain PAS_10 PF13596.6 KFH46470.1 - 0.0096 16.5 0.0 5.7 7.6 0.0 3.5 3 0 0 3 3 3 1 PAS domain DUF1772 PF08592.11 KFH46471.1 - 6.4e-25 88.1 4.2 7.1e-25 87.9 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Cornichon PF03311.14 KFH46472.1 - 1.1e-49 167.9 10.8 1.2e-49 167.7 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein Syntaxin PF00804.25 KFH46473.1 - 7.1e-21 74.8 11.9 1.7e-20 73.5 11.9 1.6 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFH46473.1 - 8.4e-11 41.7 3.7 8.4e-11 41.7 3.7 2.4 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFH46473.1 - 0.00037 20.8 4.3 0.00037 20.8 4.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Orf78 PF06024.12 KFH46473.1 - 0.0072 16.6 0.1 0.0072 16.6 0.1 2.0 2 1 0 2 2 2 1 Orf78 (ac78) ODV-E18 PF10717.9 KFH46473.1 - 0.099 12.5 1.5 0.11 12.4 0.2 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Picorna_P3A PF06363.11 KFH46473.1 - 0.14 12.0 0.5 0.28 11.1 0.5 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein Mod_r PF07200.13 KFH46473.1 - 0.18 11.9 9.2 0.8 9.8 4.3 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RIFIN PF02009.16 KFH46473.1 - 0.25 11.2 11.7 0.041 13.8 4.4 1.9 1 1 0 2 2 2 0 Rifin BLOC1_2 PF10046.9 KFH46473.1 - 0.48 10.8 4.3 1.3 9.4 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fungal_trans PF04082.18 KFH46474.1 - 4.7e-18 65.2 0.0 2.1e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46474.1 - 2.2e-09 37.2 9.2 4.1e-09 36.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDHD PF02862.17 KFH46474.1 - 0.0017 18.6 5.6 0.0036 17.5 3.9 2.0 2 0 0 2 2 2 1 DDHD domain DUF4666 PF15697.5 KFH46474.1 - 0.0024 18.5 10.6 0.0024 18.5 10.6 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4666) SPX PF03105.19 KFH46474.1 - 0.018 15.0 15.0 1 9.2 0.1 2.1 2 0 0 2 2 2 0 SPX domain Rrn6 PF10214.9 KFH46474.1 - 0.072 11.6 27.1 0.15 10.6 27.1 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Band_3_cyto PF07565.13 KFH46474.1 - 0.072 12.9 7.1 0.13 12.1 7.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TERB2 PF15101.6 KFH46474.1 - 0.18 11.8 15.3 0.38 10.8 15.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EPL1 PF10513.9 KFH46474.1 - 0.2 12.0 13.8 0.031 14.7 9.3 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like SID-1_RNA_chan PF13965.6 KFH46474.1 - 0.22 9.9 0.2 0.31 9.4 0.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 KFH46474.1 - 0.43 8.8 25.2 0.7 8.1 25.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.8 KFH46474.1 - 0.47 9.3 16.0 0.82 8.5 16.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KFH46474.1 - 0.71 8.6 21.7 0.0072 15.1 12.5 1.9 2 0 0 2 2 2 0 Presenilin Tim54 PF11711.8 KFH46474.1 - 1.1 7.9 14.1 0.27 10.0 9.7 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 KFH46474.1 - 1.4 8.3 25.8 0.068 12.5 15.6 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Spem1 PF15670.5 KFH46474.1 - 1.4 8.5 22.9 6.2 6.3 16.0 2.3 2 0 0 2 2 2 0 Spermatid maturation protein 1 Membralin PF09746.9 KFH46474.1 - 1.4 7.9 4.7 2.5 7.0 4.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein FAM60A PF15396.6 KFH46474.1 - 1.4 8.8 13.7 0.35 10.8 9.4 1.9 2 0 0 2 2 2 0 Protein Family FAM60A TFIIA PF03153.13 KFH46474.1 - 1.6 8.6 40.9 0.03 14.3 30.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MDM10 PF12519.8 KFH46474.1 - 1.6 7.5 9.8 2.6 6.8 9.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Endostatin PF06482.11 KFH46474.1 - 2.4 7.5 14.5 0.43 10.0 10.9 1.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SAPS PF04499.15 KFH46474.1 - 3.1 6.5 10.3 0.27 10.0 3.9 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4228 PF14009.6 KFH46474.1 - 5.3 7.4 14.1 7.1 7.0 9.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF4407 PF14362.6 KFH46474.1 - 5.6 6.2 21.2 13 5.0 21.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 KFH46474.1 - 6 5.7 25.7 10 5.0 25.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPL5 PF18168.1 KFH46474.1 - 6 6.1 10.5 11 5.2 10.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 FmiP_Thoc5 PF09766.9 KFH46474.1 - 8.5 5.6 24.1 0.051 12.9 15.5 1.5 2 0 0 2 2 1 0 Fms-interacting protein/Thoc5 MAJIN PF15077.6 KFH46474.1 - 9.6 5.9 12.5 21 4.8 12.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Deltameth_res PF16020.5 KFH46475.1 - 1 9.3 3.3 0.65 9.9 0.2 2.3 2 0 0 2 2 2 0 Deltamethrin resistance CPP1-like PF11833.8 KFH46475.1 - 4.8 6.8 8.1 0.091 12.4 0.6 1.9 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PCI PF01399.27 KFH46476.1 - 0.034 14.7 0.0 0.21 12.1 0.0 2.3 2 0 0 2 2 2 0 PCI domain SET PF00856.28 KFH46477.1 - 0.00032 21.1 0.2 0.0026 18.2 0.2 2.0 1 1 0 1 1 1 1 SET domain WLM PF08325.10 KFH46478.1 - 2.4e-59 200.6 0.0 3.7e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KFH46478.1 - 4.2e-06 26.0 11.5 1.7e-05 24.0 2.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KFH46478.1 - 0.17 11.9 0.9 0.36 10.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 C1_2 PF03107.16 KFH46478.1 - 0.21 11.9 5.0 0.76 10.1 0.2 2.5 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 KFH46478.1 - 0.41 10.7 9.6 9.2 6.4 10.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KFH46478.1 - 6.9 6.8 8.5 20 5.3 0.3 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DUF1525 PF07511.11 KFH46479.1 - 0.1 12.7 3.9 1.1 9.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) DUF4239 PF14023.6 KFH46479.1 - 0.85 9.3 4.0 1.4 8.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) G_path_suppress PF15991.5 KFH46479.1 - 6 6.9 13.7 0.56 10.3 7.0 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor FUSC PF04632.12 KFH46479.1 - 7.3 5.0 5.1 8.7 4.7 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RasGAP PF00616.19 KFH46480.1 - 2.4e-48 164.6 0.0 6.2e-48 163.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFH46480.1 - 5.9e-47 159.3 3.6 2.9e-46 157.0 3.6 2.3 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 KFH46480.1 - 1.4e-19 68.0 36.2 0.0014 18.2 0.1 12.7 13 0 0 13 13 13 7 IQ calmodulin-binding motif CH PF00307.31 KFH46480.1 - 3.1e-11 43.4 0.1 1.4e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain IZUMO PF15005.6 KFH46480.1 - 2.9 8.4 4.7 3.9 8.0 0.4 3.0 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Colicin-DNase PF12639.7 KFH46480.1 - 3.1 8.7 5.4 13 6.7 1.9 3.0 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DivIC PF04977.15 KFH46480.1 - 3.5 7.5 8.9 0.55 10.0 1.0 3.2 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_S5 PF00333.20 KFH46481.1 - 5.5e-27 93.5 2.6 6.8e-27 93.2 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFH46481.1 - 5.7e-22 77.0 0.0 9.7e-22 76.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain IMS PF00817.20 KFH46482.1 - 3.2e-42 144.1 0.1 5.7e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFH46482.1 - 4.1e-14 53.3 0.0 9.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFH46482.1 - 0.004 17.4 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif PRP3 PF08572.10 KFH46482.1 - 0.054 13.2 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Abhydrolase_3 PF07859.13 KFH46483.1 - 5.1e-05 23.2 0.1 0.00013 21.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH46483.1 - 7.2e-05 23.5 1.5 0.0003 21.5 1.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH46483.1 - 0.0013 18.0 0.0 0.034 13.4 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH46483.1 - 0.0017 18.1 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FKBP_C PF00254.28 KFH46485.1 - 2e-34 117.8 0.0 2.9e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LPD30 PF18850.1 KFH46485.1 - 0.0051 16.6 0.3 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 Large polyvalent protein associated domain 30 Med8 PF10232.9 KFH46486.1 - 5.1e-40 137.5 2.1 6.6e-40 137.1 2.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Rotamase PF00639.21 KFH46486.1 - 0.088 13.8 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Lant_dehydr_C PF14028.6 KFH46486.1 - 0.16 11.5 1.3 0.15 11.6 0.2 1.5 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term CDC45 PF02724.14 KFH46486.1 - 0.21 9.8 5.4 0.28 9.4 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFH46486.1 - 6 4.9 13.1 0.33 9.1 7.9 1.5 2 0 0 2 2 2 0 Nop14-like family Cnd2 PF05786.14 KFH46486.1 - 6.2 5.3 8.4 9.5 4.7 8.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DHHC PF01529.20 KFH46487.1 - 7.9e-32 110.2 0.8 7.9e-32 110.2 0.8 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF2254 PF10011.9 KFH46487.1 - 0.05 12.4 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Transglut_core3 PF13471.6 KFH46487.1 - 0.053 13.4 0.5 0.17 11.8 0.5 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DAHP_synth_2 PF01474.16 KFH46488.1 - 2.3e-201 669.0 0.0 2.6e-201 668.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family SQHop_cyclase_C PF13243.6 KFH46490.1 - 1.8e-49 168.6 1.3 8.6e-46 156.5 0.9 2.8 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFH46490.1 - 5e-43 147.3 2.1 8.6e-38 130.1 0.1 3.3 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KFH46490.1 - 4.6e-27 93.5 10.9 8.4e-09 35.0 0.1 5.7 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KFH46490.1 - 0.00017 21.1 2.4 0.14 11.5 0.0 4.1 5 0 0 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 KFH46490.1 - 0.00022 20.4 0.6 0.0035 16.4 0.2 2.9 2 1 1 3 3 3 1 A-macroglobulin TED domain K_channel_TID PF07941.11 KFH46492.1 - 0.081 13.4 11.1 0.18 12.3 11.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TauD PF02668.16 KFH46493.1 - 7e-35 121.1 0.1 9.7e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFH46493.1 - 0.0064 15.6 0.0 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 CsiD TRI12 PF06609.13 KFH46494.1 - 8.4e-25 87.2 8.8 9.7e-25 87.0 8.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rib PF08428.10 KFH46495.1 - 0.11 12.5 0.5 0.53 10.3 0.5 1.9 1 1 0 1 1 1 0 Rib/alpha-like repeat Mg_trans_NIPA PF05653.14 KFH46498.1 - 5.2e-15 55.3 13.8 7.3e-15 54.8 13.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 KFH46498.1 - 0.00025 20.4 1.3 0.00025 20.4 1.3 2.4 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KFH46498.1 - 0.00049 20.3 20.8 0.0016 18.6 0.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family GWT1 PF06423.12 KFH46498.1 - 0.41 10.7 3.5 39 4.4 0.3 3.1 2 1 1 3 3 3 0 GWT1 TAFII28 PF04719.14 KFH46499.1 - 9.9e-31 105.7 0.1 1.6e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region EutB PF06751.11 KFH46499.1 - 0.017 14.0 0.3 0.024 13.5 0.3 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) PSD1 PF07587.11 KFH46499.1 - 0.076 12.5 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) EI24 PF07264.11 KFH46500.1 - 4.4e-12 46.6 1.4 7.2e-12 45.9 1.4 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SRF-TF PF00319.18 KFH46501.1 - 4.6e-21 74.0 0.1 6.4e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cluap1 PF10234.9 KFH46502.1 - 0.0046 16.4 11.9 0.013 14.9 11.9 1.7 1 1 0 1 1 1 1 Clusterin-associated protein-1 GvpK PF05121.12 KFH46502.1 - 0.0075 16.3 4.8 0.0075 16.3 4.8 2.6 1 1 2 3 3 3 1 Gas vesicle protein K Spc24 PF08286.11 KFH46502.1 - 0.035 14.3 1.7 0.035 14.3 1.7 3.5 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 KFH46502.1 - 0.036 14.3 3.8 0.036 14.3 3.8 4.1 3 1 2 5 5 4 0 ABC transporter C-terminal domain Filament PF00038.21 KFH46502.1 - 0.083 12.5 15.8 0.13 11.8 15.8 1.5 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 KFH46502.1 - 0.084 11.7 17.7 0.19 10.6 3.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFH46502.1 - 0.095 13.0 5.1 0.18 12.2 1.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm2_III-A PF03750.13 KFH46502.1 - 0.1 13.4 1.6 0.19 12.6 0.8 1.9 1 1 0 1 1 1 0 Csm2 Type III-A RGS-like PF09128.11 KFH46502.1 - 0.12 12.0 1.6 0.27 10.9 1.6 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF4407 PF14362.6 KFH46502.1 - 0.38 10.0 15.4 1.9 7.8 14.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KFH46502.1 - 0.53 10.7 18.1 0.48 10.9 14.4 2.1 1 1 1 2 2 2 0 Fez1 DUF4618 PF15397.6 KFH46502.1 - 0.79 9.1 11.9 0.34 10.3 4.3 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.15 KFH46502.1 - 0.93 9.3 22.8 3.8 7.3 3.5 4.1 1 1 2 4 4 4 0 Septum formation initiator FapA PF03961.13 KFH46502.1 - 1.4 7.4 7.5 0.57 8.7 4.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 KFH46502.1 - 1.7 9.2 28.8 0.061 13.9 6.8 2.6 2 1 1 3 3 2 0 Apg6 coiled-coil region OmpH PF03938.14 KFH46502.1 - 1.9 8.8 20.7 2.8 8.3 1.9 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 KFH46502.1 - 2.3 7.0 2.9 2.8 6.8 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.6 KFH46502.1 - 2.4 7.4 18.7 0.41 10.0 3.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1640 PF07798.11 KFH46502.1 - 3.5 7.7 13.8 0.35 10.9 1.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Atg14 PF10186.9 KFH46502.1 - 3.5 6.6 15.6 29 3.6 15.6 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KFH46502.1 - 3.6 7.7 21.9 8.7 6.4 3.3 3.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 KFH46502.1 - 3.8 7.7 10.1 2.2 8.5 5.8 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 PKI PF02827.16 KFH46502.1 - 4 7.7 7.9 8.7 6.6 0.8 3.3 3 0 0 3 3 3 0 cAMP-dependent protein kinase inhibitor HAUS5 PF14817.6 KFH46502.1 - 5.8 5.5 19.3 63 2.1 19.3 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 YabA PF06156.13 KFH46502.1 - 7.4 7.3 12.2 6.9 7.4 2.9 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Dyp_perox PF04261.12 KFH46504.1 - 7.3e-89 298.0 0.0 8.4e-89 297.8 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family S6PP_C PF08472.10 KFH46504.1 - 0.043 13.7 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal TRI12 PF06609.13 KFH46505.1 - 7.9e-85 285.5 19.0 1e-84 285.1 19.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH46505.1 - 1e-25 90.4 47.4 6.4e-25 87.8 45.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46505.1 - 1e-09 37.8 28.6 7.2e-07 28.4 25.8 3.6 2 1 1 3 3 3 2 Sugar (and other) transporter FixP_N PF14715.6 KFH46505.1 - 6.8 6.5 8.0 2 8.2 2.2 3.0 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DEAD PF00270.29 KFH46506.1 - 1.4e-44 152.0 0.0 2.3e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH46506.1 - 8.3e-29 100.2 0.0 7.8e-28 97.0 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFH46506.1 - 0.00016 20.6 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain UTP25 PF06862.12 KFH46506.1 - 0.031 13.1 0.0 4 6.1 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3400 PF11880.8 KFH46506.1 - 0.075 12.6 0.3 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) CMS1 PF14617.6 KFH46506.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFH46506.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1688 PF07958.11 KFH46507.1 - 6.1e-182 605.0 0.0 6.9e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PQ-loop PF04193.14 KFH46509.1 - 3.7e-37 125.9 11.8 5.1e-21 74.2 0.4 2.9 3 0 0 3 3 3 2 PQ loop repeat TMEM132D_C PF15706.5 KFH46509.1 - 0.0056 16.4 0.0 0.025 14.3 0.0 2.1 3 0 0 3 3 3 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term 7tm_3 PF00003.22 KFH46509.1 - 0.0078 16.0 2.3 0.027 14.2 2.3 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ER_lumen_recept PF00810.18 KFH46509.1 - 0.065 14.1 0.5 8.5 7.2 0.1 2.6 2 1 1 3 3 3 0 ER lumen protein retaining receptor DUF4131 PF13567.6 KFH46509.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) 60KD_IMP PF02096.20 KFH46510.1 - 8.9e-13 48.5 0.1 8.9e-13 48.5 0.1 1.4 2 0 0 2 2 2 1 60Kd inner membrane protein UQ_con PF00179.26 KFH46512.1 - 2.9e-51 172.8 0.0 3.2e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PLU-1 PF08429.11 KFH46513.1 - 5.4e-109 364.4 12.7 6.4e-104 347.8 10.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KFH46513.1 - 1.2e-43 148.2 0.4 2.7e-43 147.0 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KFH46513.1 - 4.1e-21 75.5 0.1 1.2e-20 73.9 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KFH46513.1 - 6e-19 67.7 23.8 1e-10 41.4 5.8 3.2 2 0 0 2 2 2 2 PHD-finger JmjN PF02375.17 KFH46513.1 - 2.2e-15 56.3 3.3 2.4e-15 56.2 1.9 1.9 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KFH46513.1 - 8e-12 45.4 4.5 2.3e-11 43.9 4.5 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KFH46513.1 - 8.9e-05 22.2 7.7 0.0013 18.3 0.8 2.8 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 KFH46513.1 - 0.0014 18.8 19.9 0.026 14.8 3.5 3.6 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 KFH46513.1 - 0.81 9.3 13.0 0.015 14.8 1.1 2.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KFH46513.1 - 4.3 7.5 27.9 0.37 10.9 5.8 3.3 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 KFH46513.1 - 9.1 6.3 27.6 0.078 12.9 1.0 3.6 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KFH46514.1 - 1.6e-12 47.5 4.9 2.5e-12 46.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFH46514.1 - 1.5e-09 37.5 3.9 2.4e-09 36.9 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFH46514.1 - 4.3e-09 36.3 0.0 9.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 KFH46514.1 - 6.8e-09 35.4 2.7 1.1e-08 34.8 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH46514.1 - 7.7e-09 35.7 2.5 1.5e-08 34.8 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFH46514.1 - 1.7e-08 34.1 1.9 1.7e-08 34.1 1.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFH46514.1 - 5.8e-07 29.4 2.4 9.1e-07 28.7 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH46514.1 - 2.3e-06 27.5 1.4 8.1e-06 25.8 0.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFH46514.1 - 6.8e-06 25.8 3.1 1e-05 25.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFH46514.1 - 0.00084 19.3 0.8 0.0015 18.6 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFH46514.1 - 0.0043 16.9 3.7 0.0074 16.1 3.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFH46514.1 - 0.018 14.7 3.2 0.031 13.9 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFH46514.1 - 0.032 14.4 2.8 0.11 12.7 2.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFH46514.1 - 0.075 13.2 2.7 0.26 11.5 2.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFH46514.1 - 0.25 11.2 2.6 0.44 10.4 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFH46514.1 - 0.28 11.3 3.3 0.47 10.6 2.7 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KFH46514.1 - 0.38 11.1 3.1 0.66 10.3 3.1 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KFH46514.1 - 0.55 10.2 2.7 0.98 9.4 2.7 1.4 1 0 0 1 1 1 0 PHD-finger rhaM PF05336.13 KFH46515.1 - 5.2e-37 126.2 1.4 6e-37 126.0 1.4 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Pkinase PF00069.25 KFH46516.1 - 1.3e-66 224.7 0.2 1.4e-65 221.3 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KFH46516.1 - 1.9e-42 143.7 0.5 3.3e-42 142.9 0.5 1.4 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KFH46516.1 - 4.1e-37 127.9 0.1 4.2e-36 124.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH46516.1 - 3.4e-06 26.6 0.0 6.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFH46516.1 - 0.0034 16.4 0.2 0.0068 15.4 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFH46516.1 - 0.02 14.3 0.5 0.077 12.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH46516.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH46516.1 - 0.16 11.5 1.0 0.28 10.7 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase tRNA-synt_1e PF01406.19 KFH46517.1 - 1.7e-110 369.1 0.0 2.6e-110 368.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFH46517.1 - 0.00024 20.0 0.2 0.47 9.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KFH46517.1 - 0.051 14.1 0.2 0.18 12.3 0.2 2.0 1 0 0 1 1 1 0 DALR domain tRNA-synt_1c PF00749.21 KFH46517.1 - 0.12 11.2 1.2 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF3449 PF11931.8 KFH46518.1 - 1.5e-78 262.9 0.3 1.5e-78 262.9 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KFH46518.1 - 6.3e-27 93.9 0.3 6.3e-27 93.9 0.3 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFH46518.1 - 2.8e-14 52.7 0.3 6e-14 51.6 0.3 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KFH46518.1 - 2.6e-08 34.0 1.6 2.2e-06 27.9 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFH46518.1 - 2.6e-07 30.7 0.7 2.6e-07 30.7 0.7 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFH46518.1 - 0.00066 20.0 0.2 0.024 15.0 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KFH46518.1 - 0.078 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger CmlA_N PF18456.1 KFH46518.1 - 0.091 12.0 0.7 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain zf-C2H2_4 PF13894.6 KFH46518.1 - 0.1 13.5 0.9 15 6.7 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4088 PF13317.6 KFH46518.1 - 0.12 11.9 0.9 0.25 10.9 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) PEP_mutase PF13714.6 KFH46519.1 - 1.3e-62 211.4 0.4 1.4e-62 211.3 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ADH_zinc_N PF00107.26 KFH46520.1 - 3.9e-06 26.9 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH46520.1 - 0.00014 21.7 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 KFH46521.1 - 3e-09 36.9 11.5 5.5e-09 36.0 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dor1 PF04124.12 KFH46521.1 - 0.036 12.8 0.1 0.049 12.3 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family p450 PF00067.22 KFH46522.1 - 3.6e-72 243.6 0.0 4.8e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KFH46522.1 - 1.4e-26 93.5 0.0 2.2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFH46522.1 - 2.3e-25 89.5 0.0 7e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFH46522.1 - 1.7e-12 48.0 0.0 3.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFH46522.1 - 0.0038 17.5 0.0 0.0074 16.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain MFS_1 PF07690.16 KFH46524.1 - 7.2e-28 97.5 31.3 7.2e-28 97.5 31.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46524.1 - 6.1e-27 94.6 29.2 5e-25 88.3 29.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter zf-C2H2 PF00096.26 KFH46525.1 - 3.2e-12 46.2 9.0 1.7e-05 25.0 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH46525.1 - 1.5e-09 37.9 7.3 0.00026 21.6 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH46525.1 - 1.7e-08 34.5 11.2 5.8e-06 26.5 1.6 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFH46525.1 - 5.5e-06 26.2 2.9 0.0048 16.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH46525.1 - 0.00021 21.5 2.0 0.029 14.6 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KFH46525.1 - 0.0011 19.2 1.6 1.3 9.3 0.0 2.6 2 1 1 3 3 3 2 BolA-like protein zf-C2H2_11 PF16622.5 KFH46525.1 - 0.0019 17.9 0.9 0.8 9.5 0.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 KFH46525.1 - 0.027 14.5 1.5 0.078 13.0 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger FYDLN_acid PF09538.10 KFH46525.1 - 0.04 14.6 4.0 0.091 13.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFH46525.1 - 0.18 12.0 7.9 5.8 7.2 1.0 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 KFH46525.1 - 0.24 11.9 11.2 0.8 10.2 1.0 2.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 KFH46525.1 - 0.6 10.4 0.1 0.6 10.4 0.1 2.4 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFH46525.1 - 1.2 9.1 6.7 0.17 11.9 2.1 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Evr1_Alr PF04777.13 KFH46525.1 - 4.4 7.8 6.9 1.7e+02 2.7 6.9 2.5 1 1 0 1 1 1 0 Erv1 / Alr family TOM13 PF08219.11 KFH46526.1 - 9.2e-37 124.9 0.0 1.2e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Methyltransf_23 PF13489.6 KFH46527.1 - 4.5e-14 52.6 0.0 6.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46527.1 - 1.3e-12 47.7 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH46527.1 - 2.6e-12 47.2 0.0 6.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH46527.1 - 2.3e-11 44.2 0.0 5.3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46527.1 - 4.5e-11 43.4 0.1 1.3e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH46527.1 - 3.3e-06 26.6 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFH46527.1 - 0.0021 17.6 1.9 0.014 15.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase small domain DREV PF05219.12 KFH46527.1 - 0.073 12.2 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase Trypsin PF00089.26 KFH46528.1 - 0.041 13.7 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Trypsin Uds1 PF15456.6 KFH46529.1 - 0.025 14.8 5.0 0.039 14.1 5.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Nup54 PF13874.6 KFH46529.1 - 0.09 12.9 6.3 0.99 9.5 3.1 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FYVE_2 PF02318.16 KFH46529.1 - 0.2 11.9 2.0 0.23 11.7 0.5 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger PAF-AH_p_II PF03403.13 KFH46530.1 - 9.4e-40 136.3 0.0 1.7e-38 132.1 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFH46530.1 - 0.00011 21.2 0.0 0.00046 19.2 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFH46530.1 - 0.006 15.6 0.1 0.0099 14.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KFH46530.1 - 0.0098 15.2 0.1 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFH46530.1 - 0.012 16.2 2.3 0.026 15.1 1.1 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ank_2 PF12796.7 KFH46532.1 - 3.6e-20 72.4 0.8 2.4e-12 47.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH46532.1 - 2.4e-12 46.8 0.2 1.5e-07 31.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFH46532.1 - 8e-12 45.4 1.3 6.4e-06 26.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH46532.1 - 8.9e-08 32.2 0.3 0.00023 21.4 0.2 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFH46532.1 - 5.3e-07 29.5 0.0 0.0053 17.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat SEP PF08059.13 KFH46534.1 - 2e-23 82.7 0.0 4.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KFH46534.1 - 4e-13 49.0 0.0 6.9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFH46534.1 - 9.6e-11 41.7 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Cwf_Cwc_15 PF04889.12 KFH46534.1 - 0.51 10.0 2.1 0.74 9.5 2.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SGS PF05002.15 KFH46535.1 - 1.9e-28 98.4 3.5 1.9e-28 98.4 3.5 2.5 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KFH46535.1 - 7.8e-08 33.2 0.2 1.5e-07 32.3 0.2 1.5 1 0 0 1 1 1 1 CS domain DUF3856 PF12968.7 KFH46535.1 - 0.059 13.4 3.3 0.06 13.4 0.4 2.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 KFH46535.1 - 0.063 13.4 3.6 5.7 7.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CNOT1_TTP_bind PF16417.5 KFH46535.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF2057 PF09829.9 KFH46535.1 - 0.17 12.0 12.4 0.054 13.7 2.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Selenoprotein_S PF06936.11 KFH46536.1 - 0.035 13.9 1.5 0.044 13.6 1.5 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) eRF1_3 PF03465.15 KFH46536.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 eRF1 domain 3 DUF1996 PF09362.10 KFH46537.1 - 7.3e-78 261.8 0.5 1.7e-77 260.6 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Glyco_transf_21 PF13506.6 KFH46538.1 - 1.3e-15 57.3 0.2 2.6e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFH46538.1 - 2.3e-08 34.2 0.0 5.4e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFH46538.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.17 KFH46540.1 - 1.4e-17 63.5 0.1 2.7e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KFH46540.1 - 0.00027 20.5 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Amidohydro_1 PF01979.20 KFH46541.1 - 2.1e-09 37.2 0.1 5.4e-08 32.5 0.1 3.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KFH46541.1 - 1.1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 KFH46541.1 - 0.0068 16.9 0.1 0.026 15.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain S1-P1_nuclease PF02265.16 KFH46542.1 - 2.8e-70 237.0 0.2 3.2e-70 236.8 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease vATP-synt_E PF01991.18 KFH46544.1 - 5.4e-67 225.1 12.5 6.4e-67 224.8 12.5 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Methyltransf_7 PF03492.15 KFH46544.1 - 0.043 13.0 3.2 0.4 9.9 4.2 1.8 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DUF4422 PF14393.6 KFH46544.1 - 0.66 9.8 5.9 0.72 9.6 2.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) DUF4288 PF14119.6 KFH46544.1 - 1.1 9.8 5.4 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF3574 PF12098.8 KFH46544.1 - 1.2 9.0 4.7 1.3 8.8 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3574) Gluconate_2-dh3 PF13618.6 KFH46544.1 - 3.3 7.9 8.3 3.3 8.0 3.3 2.8 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 ATP-synt_B PF00430.18 KFH46544.1 - 4.4 7.4 23.4 2.5 8.2 7.5 3.1 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) Folliculin PF11704.8 KFH46544.1 - 9.3 6.1 10.9 26 4.6 11.0 1.8 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Aldedh PF00171.22 KFH46545.1 - 1e-119 400.1 0.1 1.3e-119 399.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LANC_like PF05147.13 KFH46546.1 - 6e-30 104.0 0.0 3.8e-29 101.4 0.0 1.9 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein TPP_enzyme_N PF02776.18 KFH46548.1 - 1.4e-41 142.0 0.3 6.8e-41 139.7 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFH46548.1 - 2.4e-21 76.1 0.1 5.9e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFH46548.1 - 3.5e-12 46.2 0.0 1.1e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GTP_cyclohydroI PF01227.22 KFH46549.1 - 4.3e-74 247.8 0.2 6.2e-74 247.3 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFH46549.1 - 0.00088 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 KFH46549.1 - 0.041 13.2 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) RRF PF01765.19 KFH46549.1 - 0.084 12.8 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Ribosome recycling factor Transposase_20 PF02371.16 KFH46549.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Pec_lyase_C PF00544.19 KFH46551.1 - 4.7e-37 127.6 4.5 6.3e-37 127.2 4.5 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFH46551.1 - 3.1e-06 27.1 4.8 0.00011 22.1 4.8 2.2 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KFH46551.1 - 0.088 12.1 3.0 0.42 9.8 0.9 2.1 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Tetraspanin PF00335.20 KFH46552.1 - 0.01 15.5 7.1 0.017 14.8 7.1 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF4282 PF14110.6 KFH46552.1 - 5.7 7.7 9.6 0.24 12.1 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Ipi1_N PF12333.8 KFH46553.1 - 2.1e-26 92.5 0.2 1.4e-25 89.9 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation UPF0113 PF03657.13 KFH46554.1 - 1.2e-23 83.2 0.0 1.9e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KFH46554.1 - 3.1e-22 78.9 0.0 4.3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PhoLip_ATPase_C PF16212.5 KFH46556.1 - 2.5e-73 246.9 27.1 2.5e-73 246.9 27.1 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFH46556.1 - 2.1e-19 69.0 2.1 8.6e-19 67.0 2.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFH46556.1 - 1.5e-13 50.7 0.2 1.1e-12 47.9 0.0 2.4 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH46556.1 - 2.4e-09 37.8 7.1 7.6e-06 26.4 1.5 3.4 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFH46556.1 - 0.00011 21.8 0.0 0.00044 19.8 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFH46556.1 - 0.011 15.5 0.3 0.033 13.9 0.3 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HGTP_anticodon PF03129.20 KFH46557.1 - 6.6e-20 71.1 0.0 1.5e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFH46557.1 - 7.2e-07 29.3 0.0 5.7e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn_clus PF00172.18 KFH46558.1 - 1e-07 32.0 12.1 1.7e-07 31.3 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 KFH46558.1 - 3.1 6.3 13.4 2.9 6.3 2.4 2.1 2 0 0 2 2 2 0 Macoilin family Lysis_col PF02402.16 KFH46559.1 - 0.037 13.7 1.8 0.18 11.5 1.8 2.2 1 0 0 1 1 1 0 Lysis protein DUF4719 PF15843.5 KFH46559.1 - 0.12 12.4 1.0 0.27 11.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DUF4131 PF13567.6 KFH46559.1 - 0.36 10.5 7.0 8.1 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) LIP PF03583.14 KFH46560.1 - 8.2e-09 35.2 0.3 0.00025 20.5 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 KFH46560.1 - 1.2e-08 35.9 12.9 2.4e-08 34.9 12.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH46560.1 - 2.5e-06 26.9 0.0 8.8e-06 25.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH46560.1 - 0.0015 18.2 2.7 0.18 11.4 2.8 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFH46560.1 - 0.11 12.0 0.0 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family CBM9_1 PF06452.11 KFH46560.1 - 0.26 11.2 0.1 0.39 10.6 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate family 9 binding domain-like MFS_1 PF07690.16 KFH46561.1 - 1e-28 100.3 30.0 1e-28 100.3 30.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PMP1_2 PF08114.11 KFH46561.1 - 7.8 6.3 7.2 4.8 7.0 0.1 3.4 4 0 0 4 4 4 0 ATPase proteolipid family DUF1010 PF06231.11 KFH46563.1 - 0.0019 18.7 0.8 0.0038 17.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1010) PTP_tm PF18861.1 KFH46563.1 - 0.04 13.9 0.7 0.099 12.6 0.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 KFH46563.1 - 0.049 12.4 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless Lsm_interact PF05391.11 KFH46563.1 - 0.085 12.4 0.6 0.2 11.2 0.6 1.6 1 0 0 1 1 1 0 Lsm interaction motif MIB_HERC2 PF06701.13 KFH46563.1 - 0.61 10.4 3.2 0.35 11.1 0.7 1.8 2 0 0 2 2 2 0 Mib_herc2 TPR_2 PF07719.17 KFH46564.1 - 3.5e-06 26.7 0.0 1.1 9.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFH46564.1 - 1.2e-05 24.9 0.2 0.077 12.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFH46564.1 - 4.1e-05 23.8 0.1 0.00083 19.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH46564.1 - 0.0036 17.9 0.2 0.015 16.0 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat UBA PF00627.31 KFH46564.1 - 0.0047 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 KFH46564.1 - 0.035 14.2 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 DnaJ domain TPR_19 PF14559.6 KFH46564.1 - 0.046 14.2 1.0 0.15 12.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.18 KFH46565.1 - 1.2e-38 133.1 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFH46565.1 - 1.6e-28 99.6 0.0 6.2e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH46565.1 - 0.16 12.2 0.1 0.49 10.6 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 KFH46566.1 - 4.3e-10 40.0 0.0 2.4e-06 28.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH46566.1 - 1.8e-07 30.9 0.0 1.3 9.8 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KFH46566.1 - 2e-07 31.4 0.0 0.016 15.8 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH46566.1 - 2.4e-07 30.9 0.3 0.0025 18.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 KFH46567.1 - 4.4e-20 71.9 27.3 7.6e-20 71.1 27.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily GIY-YIG PF01541.24 KFH46568.1 - 1.4e-12 47.7 0.0 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 KFH46568.1 - 0.031 14.5 0.1 0.053 13.7 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFH46568.1 - 0.075 13.3 1.2 0.12 12.6 1.2 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain T5orf172 PF10544.9 KFH46568.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain Prok-RING_1 PF14446.6 KFH46568.1 - 0.78 9.7 5.7 2 8.4 1.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Transferase PF02458.15 KFH46569.1 - 4.6e-10 38.7 0.0 1.7e-08 33.6 0.0 2.6 2 1 0 2 2 2 2 Transferase family GCD14 PF08704.10 KFH46571.1 - 1.5e-62 211.5 0.0 4.3e-44 151.0 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit DEAD PF00270.29 KFH46572.1 - 5.1e-42 143.6 0.2 8.5e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH46572.1 - 2.7e-33 114.6 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFH46572.1 - 0.00051 19.8 0.1 0.00076 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFH46572.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFH46572.1 - 0.0014 19.0 0.1 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KFH46572.1 - 0.057 13.4 0.3 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain DUF5393 PF17371.2 KFH46572.1 - 0.062 11.4 0.1 0.096 10.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) TniB PF05621.11 KFH46572.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KFH46572.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KFH46572.1 - 0.13 12.5 0.8 0.65 10.3 0.8 2.0 1 1 0 1 1 1 0 AAA domain Trypsin PF00089.26 KFH46573.1 - 4.3e-16 59.4 0.1 4.7e-16 59.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin LSM PF01423.22 KFH46575.1 - 6.1e-07 29.0 0.6 6.8e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 LSM domain Malate_synthase PF01274.22 KFH46576.1 - 2e-229 762.3 0.0 2.2e-229 762.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_17 PF00332.18 KFH46577.1 - 3.3e-31 109.1 0.2 3.3e-30 105.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 HpcH_HpaI PF03328.14 KFH46577.1 - 0.041 13.0 0.1 0.08 12.1 0.1 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 KFH46578.1 - 2.1e-11 43.4 0.1 3.6e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46578.1 - 1e-08 35.1 12.7 1.7e-08 34.4 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Voldacs PF03517.13 KFH46579.1 - 6.8e-18 65.1 2.7 1.7e-17 63.8 2.7 1.7 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling 2OG-FeII_Oxy_5 PF13759.6 KFH46579.1 - 0.057 13.8 0.0 3.3 8.2 0.0 2.6 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase TFIIE-A_C PF11521.8 KFH46579.1 - 2 8.7 5.6 4.7 7.6 1.1 3.0 3 1 1 4 4 4 0 C-terminal general transcription factor TFIIE alpha Gtr1_RagA PF04670.12 KFH46580.1 - 6.6e-87 290.7 0.0 1e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFH46580.1 - 6.4e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFH46580.1 - 1.9e-06 27.6 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFH46580.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFH46580.1 - 7.7e-05 22.2 0.1 0.0002 20.9 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFH46580.1 - 0.0014 17.8 3.3 0.36 9.9 0.5 2.7 2 1 1 3 3 3 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KFH46580.1 - 0.0038 17.1 0.5 0.091 12.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFH46580.1 - 0.0041 16.8 0.9 0.053 13.3 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFH46580.1 - 0.0057 17.2 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KFH46580.1 - 0.013 15.0 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KFH46580.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFH46580.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Robl_LC7 PF03259.17 KFH46581.1 - 1.1e-08 34.7 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Roadblock/LC7 domain Gly_transf_sug PF04488.15 KFH46583.1 - 3.9e-06 27.4 0.5 1.1e-05 26.0 0.5 1.6 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif UPF0139 PF03669.13 KFH46586.1 - 2.2e-09 37.0 0.1 2.8e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Peptidase_M14 PF00246.24 KFH46587.1 - 1.3e-14 54.7 0.0 8.1e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFH46587.1 - 0.0003 20.0 0.7 0.0029 16.7 0.7 2.2 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 KFH46587.1 - 0.052 12.9 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Aa_trans PF01490.18 KFH46589.1 - 1.1e-31 110.0 32.3 1.3e-31 109.8 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFH46589.1 - 1.3e-06 27.8 12.4 1.3e-06 27.8 12.4 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family NAD_binding_8 PF13450.6 KFH46589.1 - 0.13 12.6 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sugar_tr PF00083.24 KFH46590.1 - 8.7e-77 258.9 21.2 1e-76 258.7 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46590.1 - 4.2e-26 91.7 25.5 5e-23 81.6 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH46590.1 - 0.00019 20.1 24.1 0.00029 19.5 4.8 2.4 2 1 1 3 3 3 3 MFS/sugar transport protein dCMP_cyt_deam_1 PF00383.23 KFH46590.1 - 0.019 14.8 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF368 PF04018.13 KFH46590.1 - 0.081 12.5 9.5 0.096 12.3 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF368) 7TM-7TMR_HD PF07698.11 KFH46590.1 - 1.1 9.0 15.0 0.36 10.6 5.9 2.7 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Trep_Strep PF09605.10 KFH46590.1 - 9.2 6.2 17.1 1.1 9.2 6.5 2.9 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF5628 PF18621.1 KFH46592.1 - 0.13 12.7 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5628) TPR_2 PF07719.17 KFH46593.1 - 5.4e-31 104.2 16.2 0.00075 19.4 0.2 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH46593.1 - 3e-27 94.7 14.8 2.6e-23 82.0 0.1 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFH46593.1 - 4.8e-27 92.6 8.1 0.00012 21.7 0.4 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFH46593.1 - 9e-21 74.2 13.1 0.019 15.5 0.0 7.7 5 2 1 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFH46593.1 - 8.7e-19 66.1 2.5 0.016 15.4 0.1 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFH46593.1 - 5.6e-17 61.8 25.0 5.5e-08 33.0 0.2 9.0 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFH46593.1 - 2.8e-13 49.5 23.2 0.17 12.8 0.4 10.2 7 4 3 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFH46593.1 - 4.9e-11 41.8 12.7 0.34 11.0 0.2 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH46593.1 - 9e-11 41.3 6.9 0.0032 17.3 0.3 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFH46593.1 - 2.4e-10 40.9 26.8 0.12 13.0 0.2 9.2 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFH46593.1 - 6.7e-08 32.6 6.9 0.0013 18.8 1.6 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH46593.1 - 1.3e-05 24.8 6.5 2.5 7.8 0.0 7.3 7 2 3 10 10 10 2 TPR repeat TPR_6 PF13174.6 KFH46593.1 - 2.6e-05 24.6 9.8 0.93 10.3 0.1 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFH46593.1 - 0.0023 17.4 3.7 6.2 6.1 0.0 4.2 5 0 0 5 5 5 1 Coatomer epsilon subunit TPR_21 PF09976.9 KFH46593.1 - 0.035 13.8 5.9 0.6 9.8 0.6 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KFH46593.1 - 0.1 12.9 1.5 0.42 10.9 0.2 2.8 2 1 0 2 2 1 0 Tetratrico peptide repeat Mito_fiss_reg PF05308.11 KFH46594.1 - 3.9 7.5 9.5 1.9 8.5 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Fungal_trans_2 PF11951.8 KFH46595.1 - 2.5e-22 79.2 2.0 8.5e-19 67.6 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46595.1 - 3.3e-08 33.5 8.7 8.5e-08 32.2 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CD47 PF04549.14 KFH46596.1 - 2.5 8.3 10.3 0.27 11.4 2.2 2.2 2 0 0 2 2 2 0 CD47 transmembrane region SKIP_SNW PF02731.15 KFH46597.1 - 5.1e-68 227.8 9.1 5.1e-68 227.8 9.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain PI3K_1B_p101 PF10486.9 KFH46597.1 - 0.89 7.3 11.9 1.2 6.8 11.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAD_binding_4 PF01565.23 KFH46599.1 - 5.4e-24 84.5 0.4 9.3e-24 83.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KFH46599.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Pet127 PF08634.10 KFH46601.1 - 9.9e-117 389.2 0.3 1.4e-116 388.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PNRC PF15365.6 KFH46601.1 - 1.3 8.9 4.1 3.9 7.4 4.1 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ank_4 PF13637.6 KFH46602.1 - 1.4e-12 47.8 0.6 0.0013 19.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH46602.1 - 1.9e-12 47.6 1.2 2.7e-06 27.9 0.6 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH46602.1 - 9.2e-11 41.8 1.7 8e-06 26.0 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFH46602.1 - 3.4e-10 39.9 1.6 0.00056 20.2 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFH46602.1 - 1.4e-08 34.3 0.4 0.024 15.1 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KFH46602.1 - 7.9e-07 28.9 0.1 9.7e-06 25.4 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain AAA_13 PF13166.6 KFH46602.1 - 0.0047 15.6 5.6 0.0047 15.6 5.6 1.5 1 1 0 1 1 1 1 AAA domain Phage-Gp8 PF09215.10 KFH46602.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 Exonuc_VII_L PF02601.15 KFH46602.1 - 0.39 10.2 8.1 0.82 9.2 8.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_A3L PF05288.11 KFH46602.1 - 0.46 10.5 1.9 0.62 10.1 0.3 2.0 2 0 0 2 2 2 0 Poxvirus A3L Protein HET PF06985.11 KFH46603.1 - 3.7e-29 101.9 0.0 6.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec2p PF06428.11 KFH46605.1 - 2.2e-12 46.8 7.3 2.2e-12 46.8 7.3 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p CCDC53 PF10152.9 KFH46605.1 - 0.00089 19.7 0.1 0.00089 19.7 0.1 2.7 2 1 1 3 3 3 1 Subunit CCDC53 of WASH complex NeA_P2 PF12312.8 KFH46605.1 - 0.0087 15.5 0.2 0.02 14.3 0.2 1.6 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.11 KFH46605.1 - 0.075 13.1 0.9 0.075 13.1 0.9 3.5 1 1 3 4 4 3 0 Mitochondrial fission regulator BRI3BP PF14965.6 KFH46605.1 - 0.12 11.9 0.7 5.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF3292 PF11696.8 KFH46605.1 - 0.17 10.3 4.2 0.27 9.5 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF737 PF05300.11 KFH46605.1 - 0.21 11.9 16.7 0.44 10.9 16.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) BST2 PF16716.5 KFH46605.1 - 0.23 12.1 15.6 2.3 8.9 0.1 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 KFH46605.1 - 0.65 8.8 17.0 0.71 8.7 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Vac_Fusion PF02346.16 KFH46605.1 - 1.5 8.5 5.5 26 4.5 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FUSC PF04632.12 KFH46605.1 - 1.6 7.1 15.9 1.2 7.5 0.4 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 KFH46605.1 - 1.7 8.9 25.1 1.4 9.1 17.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 KFH46605.1 - 5.5 6.0 20.9 1.3e+03 -1.8 21.0 2.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HA2 PF04408.23 KFH46606.1 - 5.8e-26 90.9 0.0 5.8e-26 90.9 0.0 2.7 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH46606.1 - 3.4e-11 43.5 0.1 1.7e-10 41.2 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH46606.1 - 1.8e-09 37.6 0.2 3.9e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KFH46606.1 - 2.5e-09 37.4 0.0 5.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KFH46606.1 - 8.8e-05 22.8 0.1 0.00039 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH46606.1 - 0.00058 19.6 0.7 0.0024 17.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFH46606.1 - 0.00071 19.9 0.1 0.0018 18.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFH46606.1 - 0.0075 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KFH46606.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KFH46606.1 - 0.036 13.3 0.0 0.036 13.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KFH46606.1 - 0.037 14.5 8.2 0.049 14.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFH46606.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 KFH46606.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DpnI_C PF17726.1 KFH46606.1 - 0.7 10.1 2.9 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Dam-replacing HTH domain PGP_phosphatase PF09419.10 KFH46607.1 - 3.4e-65 218.8 0.0 3.9e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KFH46607.1 - 0.00028 20.9 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFH46607.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PhoD PF09423.10 KFH46610.1 - 5.4e-46 157.2 0.0 1.1e-45 156.2 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase ArgJ PF01960.18 KFH46611.1 - 1.2e-148 494.8 0.0 1.4e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Med6 PF04934.14 KFH46612.1 - 5.9e-39 132.9 0.0 8.2e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component ACT_7 PF13840.6 KFH46613.1 - 9.7e-26 89.4 0.0 3.5e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ACT domain Carn_acyltransf PF00755.20 KFH46614.1 - 2.2e-91 307.3 0.0 4.9e-91 306.1 0.0 1.6 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KFH46614.1 - 2.9e-71 240.0 0.0 5.4e-71 239.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFH46614.1 - 1.1e-55 189.4 0.1 2e-55 188.6 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFH46614.1 - 1e-50 172.2 0.0 2.8e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFH46614.1 - 8.9e-43 146.6 0.2 2e-42 145.5 0.2 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFH46614.1 - 2.8e-40 137.0 0.1 6.7e-40 135.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH46614.1 - 4.4e-19 69.1 0.0 1.9e-18 67.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFH46614.1 - 5.9e-14 52.5 0.7 4.6e-12 46.4 0.7 3.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFH46614.1 - 8.4e-13 48.8 0.0 5.6e-12 46.2 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KFH46614.1 - 1.4e-12 48.8 0.0 7.2e-09 36.8 0.0 4.1 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH46614.1 - 2.7e-12 46.8 0.0 5.5e-11 42.6 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KFH46614.1 - 2.7e-12 47.2 0.0 1.2e-11 45.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH46614.1 - 1.9e-11 44.0 0.0 4.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH46614.1 - 3.7e-09 36.6 0.0 1.2e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFH46614.1 - 1.1e-08 34.7 0.0 1.1e-07 31.5 0.0 2.5 3 0 0 3 3 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KFH46614.1 - 2.3e-08 33.7 0.0 6.7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KFH46614.1 - 2.6e-05 23.9 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KFH46614.1 - 2.9e-05 24.3 0.0 6.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFH46614.1 - 0.0065 15.9 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.18 KFH46614.1 - 0.018 14.3 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 KFH46614.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KFH46614.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_16 PF10294.9 KFH46614.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 KFH46614.1 - 0.17 11.0 0.0 0.55 9.3 0.0 1.8 2 0 0 2 2 1 0 Histidine-specific methyltransferase, SAM-dependent NAD_binding_10 PF13460.6 KFH46614.1 - 8.3 6.3 8.6 2.6 7.9 0.3 3.6 5 0 0 5 5 4 0 NAD(P)H-binding Metallophos PF00149.28 KFH46615.1 - 2.4e-37 129.4 0.1 5.8e-37 128.2 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_membrane PF00664.23 KFH46616.1 - 1.5e-53 182.2 27.2 1.1e-33 117.1 15.5 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KFH46616.1 - 6.6e-47 159.5 0.0 7.7e-27 94.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KFH46616.1 - 9.8e-06 26.1 0.0 0.089 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFH46616.1 - 0.00011 22.3 3.4 0.092 12.8 0.3 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KFH46616.1 - 0.00014 21.4 1.1 4 6.8 0.0 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH46616.1 - 0.00029 20.5 1.5 0.26 11.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH46616.1 - 0.0005 20.0 1.5 0.088 12.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KFH46616.1 - 0.00086 18.6 0.0 0.08 12.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 KFH46616.1 - 0.0013 18.9 2.4 0.19 11.8 0.3 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KFH46616.1 - 0.0028 17.4 1.2 2.6 7.7 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KFH46616.1 - 0.0095 15.8 2.6 1.2 8.9 0.3 2.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KFH46616.1 - 0.016 15.3 6.7 0.074 13.1 0.7 2.6 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 KFH46616.1 - 0.021 13.8 2.4 3.6 6.5 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFH46616.1 - 0.049 13.9 1.8 13 6.0 0.2 3.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFH46616.1 - 0.076 13.4 0.2 29 5.1 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 KFH46616.1 - 0.12 11.9 0.5 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 KFH46616.1 - 0.13 12.2 0.1 21 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 KFH46616.1 - 0.16 12.2 0.4 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 KFH46616.1 - 0.18 10.7 0.8 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF4530 PF15039.6 KFH46616.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4530) AAA_23 PF13476.6 KFH46616.1 - 1.9 8.9 6.5 23 5.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KFH46616.1 - 6.5 6.5 5.4 18 5.0 0.2 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF2207 PF09972.9 KFH46616.1 - 7.2 5.2 16.0 1.9 7.1 0.0 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Hid1 PF12722.7 KFH46617.1 - 3.1e-300 998.1 0.0 3.5e-300 997.9 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFH46617.1 - 3.2e-98 329.8 0.0 3.9e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein 2-Hacid_dh_C PF02826.19 KFH46618.1 - 1.2e-50 171.4 0.0 2.1e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH46618.1 - 2e-15 56.6 0.0 2.8e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFH46618.1 - 0.00032 20.9 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KFH46618.1 - 0.0095 15.2 0.2 0.55 9.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain UCH PF00443.29 KFH46619.1 - 1e-31 110.4 0.0 1.9e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH46619.1 - 6e-06 26.1 0.0 2.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S20p PF01649.18 KFH46619.1 - 0.029 15.0 0.0 0.055 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 Sec8_exocyst PF04048.14 KFH46620.1 - 2.3e-48 163.7 1.6 5.1e-48 162.6 0.9 2.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KFH46620.1 - 2.8e-10 40.0 0.6 5e-10 39.1 0.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Swi5 PF07061.11 KFH46620.1 - 0.0063 16.6 0.1 0.023 14.8 0.1 2.0 1 0 0 1 1 1 1 Swi5 ApoLp-III PF07464.11 KFH46620.1 - 0.023 14.8 0.2 0.94 9.6 0.0 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) YcbB PF08664.10 KFH46620.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 YcbB domain Sec2p PF06428.11 KFH46620.1 - 0.16 12.0 2.8 7.2 6.7 0.2 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Vps53_N PF04100.12 KFH46620.1 - 0.18 10.8 0.6 0.35 9.8 0.6 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal Lebercilin PF15619.6 KFH46620.1 - 0.27 10.9 3.1 0.53 9.9 1.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3619 PF12279.8 KFH46621.1 - 0.047 14.0 2.9 0.47 10.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3619) TauD PF02668.16 KFH46622.1 - 2.6e-37 129.1 0.0 3.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFH46622.1 - 0.049 12.7 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 CsiD Pkinase PF00069.25 KFH46623.1 - 8.8e-65 218.7 0.0 1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46623.1 - 5.3e-25 88.2 0.0 7.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH46623.1 - 1.5e-06 27.7 0.0 6.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFH46623.1 - 0.00089 19.2 0.0 0.0061 16.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KFH46623.1 - 0.038 14.2 0.1 0.06 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Kdo PF06293.14 KFH46623.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFH46623.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3433 PF11915.8 KFH46624.1 - 1.9e-39 134.0 9.3 6.5e-22 77.8 1.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) COMPASS-Shg1 PF05205.12 KFH46625.1 - 4.1e-22 78.8 0.1 4.1e-22 78.8 0.1 2.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Mito_carr PF00153.27 KFH46626.1 - 2.9e-13 49.5 6.1 0.00027 20.8 0.0 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein GGACT PF06094.12 KFH46628.1 - 5.2e-21 75.5 0.1 7.5e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like RPA43_OB PF17875.1 KFH46629.1 - 6e-33 114.1 0.2 6e-33 114.1 0.2 4.4 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I DUF4778 PF16008.5 KFH46629.1 - 2 8.4 11.4 1 9.4 9.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) GREB1 PF15782.5 KFH46629.1 - 4.9 4.1 16.9 6 3.8 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer adh_short PF00106.25 KFH46630.1 - 2.7e-43 147.7 0.1 3.5e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46630.1 - 1.7e-39 135.8 1.6 6.5e-39 133.9 1.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH46630.1 - 3.5e-07 30.3 0.3 6.6e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH46630.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFH46630.1 - 0.0016 18.3 0.5 0.018 14.9 0.5 2.1 1 1 0 1 1 1 1 NAD(P)H-binding LDcluster4 PF18306.1 KFH46630.1 - 0.0069 16.0 1.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 SLOG cluster4 family GDP_Man_Dehyd PF16363.5 KFH46630.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KFH46630.1 - 0.045 13.6 0.6 3.3 7.6 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFH46630.1 - 0.053 12.6 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KFH46630.1 - 0.076 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EXS PF03124.14 KFH46631.1 - 1.7e-99 333.3 26.3 2.1e-99 333.0 26.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFH46631.1 - 2.5e-81 274.6 5.9 2.5e-81 274.6 5.9 2.1 2 0 0 2 2 2 1 SPX domain DUF2975 PF11188.8 KFH46631.1 - 0.55 10.1 2.7 1.5 8.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Myc_N PF01056.18 KFH46631.1 - 1.3 8.9 14.1 3.9 7.3 6.9 2.4 2 0 0 2 2 2 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 KFH46631.1 - 1.3 9.2 20.1 1.2 9.4 1.2 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KFH46631.1 - 2.7 7.5 11.5 6.1 6.3 6.0 2.4 2 0 0 2 2 2 0 PPP4R2 FAM176 PF14851.6 KFH46631.1 - 5.4 6.7 15.0 7.2 6.3 0.6 2.7 2 0 0 2 2 2 0 FAM176 family Fer2 PF00111.27 KFH46632.1 - 5.2e-14 52.0 0.6 7.7e-14 51.4 0.6 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain YcgR_2 PF12945.7 KFH46632.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Flagellar protein YcgR DUF2500 PF10694.9 KFH46632.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) NDUF_B7 PF05676.13 KFH46633.1 - 6.2e-31 105.9 5.5 7.2e-31 105.7 5.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KFH46633.1 - 0.00052 20.0 2.6 0.00063 19.7 2.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MFS_1 PF07690.16 KFH46634.1 - 3e-29 102.1 27.4 5.3e-29 101.2 27.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46634.1 - 2.5e-09 36.5 12.5 4e-09 35.9 12.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFH46634.1 - 1.4e-07 30.3 5.7 1.7e-07 30.0 5.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH46635.1 - 1.2e-101 340.8 15.9 1.4e-101 340.6 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46635.1 - 1.5e-13 50.4 29.2 1.5e-13 50.4 29.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KFH46637.1 - 1.7e-22 80.5 0.0 3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFH46637.1 - 0.00083 20.0 0.0 0.0014 19.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFH46637.1 - 0.038 14.2 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 KFH46638.1 - 1.2e-97 328.0 0.0 1.4e-97 327.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH46638.1 - 2.2e-05 24.6 0.2 9e-05 22.6 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH46638.1 - 2.4e-05 23.6 0.7 3.9e-05 22.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH46638.1 - 0.00093 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFH46638.1 - 0.0048 16.0 0.4 0.0048 16.0 0.4 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KFH46638.1 - 0.0052 16.4 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH46638.1 - 0.098 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFH46638.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH46638.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain Abhydrolase_6 PF12697.7 KFH46640.1 - 3.9e-07 30.9 1.0 1.8e-06 28.7 1.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.28 KFH46641.1 - 6.7e-35 120.5 0.0 9.9e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFH46641.1 - 4.7e-07 29.6 0.4 1.1e-06 28.4 0.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KFH46641.1 - 0.00043 21.2 0.1 0.00088 20.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 KFH46642.1 - 5.3e-59 199.6 3.5 6.2e-59 199.4 3.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46642.1 - 1.2e-42 145.6 2.8 1.5e-42 145.3 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46642.1 - 6e-15 55.6 1.5 8.3e-15 55.2 1.5 1.1 1 0 0 1 1 1 1 KR domain Glyco_hydro_1 PF00232.18 KFH46642.1 - 0.018 13.5 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Actin PF00022.19 KFH46643.1 - 1.5e-125 419.0 0.0 6e-125 417.0 0.0 1.7 1 1 0 1 1 1 1 Actin ATP-synt_ab PF00006.25 KFH46644.1 - 3.9e-107 356.7 0.0 5.8e-107 356.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KFH46644.1 - 1.1e-46 157.7 0.0 2.9e-46 156.3 0.0 1.8 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KFH46644.1 - 5e-14 52.6 2.4 1.2e-13 51.4 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain V_ATPase_I PF01496.19 KFH46645.1 - 0.29 9.0 10.8 0.47 8.3 10.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KFH46645.1 - 0.6 9.6 15.0 0.92 9.0 15.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FPN1 PF06963.12 KFH46646.1 - 1.6e-111 373.0 20.5 1.9e-111 372.8 20.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Pyr_redox_2 PF07992.14 KFH46648.1 - 3.2e-12 46.3 0.0 6.1e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH46648.1 - 0.0015 18.2 0.3 0.015 14.9 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFH46648.1 - 0.08 13.5 0.0 3.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH46648.1 - 0.089 12.8 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding CAP_N PF01213.19 KFH46648.1 - 0.13 11.8 12.8 0.19 11.2 12.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pex14_N PF04695.13 KFH46648.1 - 0.54 10.9 4.8 0.5 11.0 3.3 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.11 KFH46648.1 - 1.1 9.2 10.5 1.8 8.6 10.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4663 PF15668.5 KFH46648.1 - 2.5 7.1 5.2 4 6.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) PRIMA1 PF16101.5 KFH46648.1 - 2.9 8.0 9.2 5.3 7.1 9.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rrn6 PF10214.9 KFH46648.1 - 5 5.5 7.2 6.5 5.1 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor p450 PF00067.22 KFH46649.1 - 1.7e-48 165.5 0.0 2.3e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EXOSC1 PF10447.9 KFH46650.1 - 5.7e-20 71.9 2.4 4.4e-14 53.0 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KFH46650.1 - 8.5e-10 38.3 0.6 1.9e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 KFH46650.1 - 0.019 15.7 0.1 0.027 15.2 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain S1 PF00575.23 KFH46650.1 - 0.037 14.4 0.4 0.28 11.6 0.4 2.2 1 1 0 1 1 1 0 S1 RNA binding domain IF-2B PF01008.17 KFH46651.1 - 1.8e-44 152.1 0.1 4.2e-44 150.8 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 KFH46651.1 - 2.1 6.9 9.8 2.8 6.5 9.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3684 PF12449.8 KFH46652.1 - 0 1473.5 0.0 0 1473.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KFH46652.1 - 8.6e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Na_H_Exchanger PF00999.21 KFH46654.1 - 1.6e-46 158.9 12.7 2.2e-46 158.4 12.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CbiM PF01891.16 KFH46654.1 - 0.6 9.9 6.3 3.5 7.4 0.0 3.7 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region TruB_N PF01509.18 KFH46655.1 - 4.1e-47 160.3 0.0 1.7e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFH46655.1 - 0.00052 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF4334 PF14232.6 KFH46657.1 - 1.4e-28 98.6 1.3 2.6e-28 97.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KFH46657.1 - 1.8e-25 88.8 0.1 2.9e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 GXWXG protein UPF0029 PF01205.19 KFH46658.1 - 1e-31 109.3 0.0 2.3e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFH46658.1 - 4e-06 27.1 0.0 7.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 RWD domain TPT PF03151.16 KFH46659.1 - 7.1e-26 91.2 17.3 8.5e-26 91.0 17.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFH46659.1 - 0.00031 20.9 37.7 0.0084 16.3 15.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KFH46659.1 - 0.00057 19.2 18.5 0.0089 15.3 18.5 2.1 1 1 0 1 1 1 1 UAA transporter family Sulfatase PF00884.23 KFH46660.1 - 0.00017 21.1 0.1 0.0026 17.2 0.1 2.0 1 1 0 1 1 1 1 Sulfatase IGPD PF00475.18 KFH46661.1 - 9e-54 181.7 0.3 2.4e-53 180.3 0.3 1.6 1 1 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase EMP24_GP25L PF01105.24 KFH46662.1 - 6e-48 163.2 2.2 6.8e-48 163.0 2.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5305 PF17231.2 KFH46662.1 - 0.022 14.2 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2569 PF10754.9 KFH46662.1 - 0.077 13.4 0.5 0.19 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) PAC3 PF10178.9 KFH46663.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DUF5081 PF16887.5 KFH46665.1 - 0.037 13.1 0.0 0.04 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) ORC2 PF04084.14 KFH46666.1 - 4.7e-121 403.8 0.0 5.8e-121 403.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 KFH46666.1 - 0.37 10.8 9.3 0.47 10.5 6.6 2.8 2 0 0 2 2 2 0 AT hook motif Glyco_hydro_11 PF00457.17 KFH46667.1 - 7.2e-76 253.8 22.8 8.7e-76 253.5 22.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF1754 PF08555.10 KFH46669.1 - 6.6e-15 55.7 16.1 1e-14 55.1 16.1 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) EHN PF06441.12 KFH46670.1 - 4.2e-25 88.2 0.5 8.5e-25 87.2 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ndc1_Nup PF09531.10 KFH46671.1 - 6.1 5.4 14.4 6.8 5.3 14.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short_C2 PF13561.6 KFH46672.1 - 4.8e-52 176.8 7.3 1.1e-51 175.7 7.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46672.1 - 4e-31 108.0 8.1 4.3e-30 104.6 8.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46672.1 - 7e-07 29.3 2.0 1.7e-06 28.0 2.0 1.7 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KFH46672.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3150 PF11348.8 KFH46672.1 - 0.16 11.2 0.0 0.37 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) MIF4G_like PF09088.11 KFH46673.1 - 2.6e-83 278.5 0.1 5.5e-83 277.4 0.1 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 KFH46673.1 - 1e-64 218.6 0.0 1.5e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 MIF4G like adh_short PF00106.25 KFH46674.1 - 6.8e-22 77.9 0.0 8.4e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KFH46674.1 - 7.4e-09 35.8 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFH46674.1 - 2.3e-07 30.6 0.0 9.4e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KFH46674.1 - 0.0021 17.3 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFH46674.1 - 0.018 14.5 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SMI1_KNR4 PF09346.10 KFH46675.1 - 9.9e-32 110.1 0.0 2e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) AA_permease_2 PF13520.6 KFH46676.1 - 7e-65 219.5 35.6 9.6e-65 219.1 35.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFH46676.1 - 9.4e-31 106.9 22.2 9.4e-31 106.9 22.2 2.2 2 0 0 2 2 2 1 Amino acid permease Glyco_hydro_61 PF03443.14 KFH46677.1 - 2.1e-05 24.6 0.1 3.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KFH46677.1 - 0.00032 21.4 0.0 0.00067 20.4 0.0 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading MMtag PF10159.9 KFH46678.1 - 2.2e-29 101.6 1.7 2.2e-29 101.6 1.7 2.5 2 1 0 2 2 2 1 Multiple myeloma tumor-associated ChlI PF13541.6 KFH46679.1 - 0.062 13.1 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase Hyd_WA PF06462.12 KFH46679.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Propeller FAT PF02259.23 KFH46680.1 - 1.2e-72 245.1 1.2 2.1e-72 244.2 1.2 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KFH46680.1 - 2.5e-32 112.7 0.1 8e-32 111.0 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFH46680.1 - 2e-06 27.5 0.1 5.1e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KFH46680.1 - 0.0025 17.8 3.1 0.23 11.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_32 PF13654.6 KFH46680.1 - 0.0055 15.6 0.1 0.014 14.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 KFH46680.1 - 0.063 13.1 4.7 1.7 8.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S3 PF14677.6 KFH46680.1 - 0.081 12.6 0.6 2.3 7.9 0.1 3.3 2 0 0 2 2 2 0 FANCI solenoid 3 TPR_8 PF13181.6 KFH46680.1 - 1.2 9.5 4.5 1 9.7 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Rrp15p PF07890.12 KFH46681.1 - 1.3e-38 132.4 10.4 1.3e-38 132.4 10.4 2.4 2 1 0 2 2 2 1 Rrp15p Yop-YscD_cpl PF16697.5 KFH46682.1 - 4.5e-05 23.7 0.0 8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KFH46682.1 - 4.5e-05 23.7 0.0 7.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Peptidase_S10 PF00450.22 KFH46683.1 - 4.3e-130 434.9 0.1 5.1e-130 434.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KFH46683.1 - 3.5e-16 59.9 0.1 1.2e-15 58.2 0.1 1.8 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide MFS_1 PF07690.16 KFH46684.1 - 0.2 10.6 13.7 0.19 10.7 12.3 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily Peptidase_M18 PF02127.15 KFH46685.1 - 3.9e-128 427.9 0.0 4.6e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFH46685.1 - 0.011 14.7 0.1 0.55 9.2 0.1 2.5 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase KASH_CCD PF14662.6 KFH46686.1 - 1.6e-05 24.8 16.4 0.013 15.3 9.9 3.1 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFH46686.1 - 0.00035 20.0 16.2 0.0045 16.4 9.8 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KFH46686.1 - 0.00064 19.8 15.2 0.35 11.0 3.0 4.3 2 2 2 4 4 4 2 bZIP transcription factor Cep57_CLD_2 PF14197.6 KFH46686.1 - 0.0098 16.0 10.9 0.0098 16.0 10.9 3.3 1 1 1 3 3 3 1 Centrosome localisation domain of PPC89 Filament PF00038.21 KFH46686.1 - 0.012 15.2 15.4 0.021 14.4 15.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein HAP1_N PF04849.13 KFH46686.1 - 0.018 14.3 17.1 0.046 12.9 16.5 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region betaPIX_CC PF16523.5 KFH46686.1 - 0.018 14.8 0.2 0.018 14.8 0.2 3.1 1 1 2 3 3 3 0 betaPIX coiled coil TSC22 PF01166.18 KFH46686.1 - 0.02 15.2 15.0 0.45 10.9 0.8 4.9 2 1 2 5 5 4 0 TSC-22/dip/bun family ZapB PF06005.12 KFH46686.1 - 0.028 14.8 22.0 0.36 11.3 1.2 4.3 2 1 1 3 3 3 0 Cell division protein ZapB AAA_27 PF13514.6 KFH46686.1 - 0.028 14.0 0.9 0.056 13.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain GIT_CC PF16559.5 KFH46686.1 - 0.047 13.6 2.2 5.1 7.1 0.1 3.3 4 0 0 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 KFH46686.1 - 0.06 13.4 2.1 0.86 9.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFH46686.1 - 0.066 12.6 4.9 0.099 12.0 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GldM_N PF12081.8 KFH46686.1 - 0.068 13.3 0.9 36 4.4 0.0 2.9 1 1 1 3 3 3 0 GldM N-terminal domain HALZ PF02183.18 KFH46686.1 - 0.081 13.2 8.5 3.2 8.0 0.1 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 KFH46686.1 - 0.099 12.4 14.5 0.16 11.7 1.5 4.1 2 1 2 4 4 4 0 Septum formation initiator ADIP PF11559.8 KFH46686.1 - 0.11 12.6 17.5 0.22 11.6 8.6 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KFH46686.1 - 0.11 12.5 18.4 0.35 10.9 11.2 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFH46686.1 - 0.15 11.0 16.7 1.7 7.4 16.6 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Lectin_N PF03954.14 KFH46686.1 - 0.32 10.7 4.0 2 8.1 3.9 2.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2968 PF11180.8 KFH46686.1 - 0.42 10.2 19.2 0.18 11.4 8.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF3450 PF11932.8 KFH46686.1 - 0.44 9.8 10.5 0.84 8.9 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 KFH46686.1 - 0.52 10.9 11.9 2.6 8.7 0.2 3.3 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 XhlA PF10779.9 KFH46686.1 - 0.99 9.6 8.9 0.54 10.5 3.2 2.8 2 2 0 2 2 2 0 Haemolysin XhlA Cnn_1N PF07989.11 KFH46686.1 - 1 9.5 14.1 11 6.2 0.3 3.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 KFH46686.1 - 1.2 7.6 2.8 1.9 7.0 2.0 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A NYD-SP28_assoc PF14775.6 KFH46686.1 - 1.2 9.2 11.9 2.1 8.5 0.3 4.0 4 0 0 4 4 4 0 Sperm tail C-terminal domain Cut12 PF11500.8 KFH46686.1 - 1.3 8.9 13.7 0.33 10.9 3.4 2.8 2 1 1 3 3 2 0 Spindle pole body formation-associated protein TMPIT PF07851.13 KFH46686.1 - 1.7 7.8 9.9 0.13 11.4 3.9 2.1 1 1 2 3 3 3 0 TMPIT-like protein Uso1_p115_C PF04871.13 KFH46686.1 - 2.3 8.6 11.7 76 3.7 11.6 2.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Taxilin PF09728.9 KFH46686.1 - 2.6 7.1 22.7 3.2 6.9 2.6 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein bZIP_2 PF07716.15 KFH46686.1 - 2.8 8.1 20.0 1.2 9.3 3.1 4.5 4 1 0 4 4 4 0 Basic region leucine zipper Csm1_N PF18504.1 KFH46686.1 - 2.9 8.3 11.7 9.4 6.7 0.3 3.6 1 1 3 4 4 4 0 Csm1 N-terminal domain Rootletin PF15035.6 KFH46686.1 - 3.6 7.6 24.8 72 3.3 24.8 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 KFH46686.1 - 4.5 7.5 16.6 8.3 6.7 6.3 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.9 KFH46686.1 - 4.6 7.6 9.8 1.6 9.0 3.5 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.9 KFH46686.1 - 4.8 7.4 28.7 0.67 10.2 15.3 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 PRKG1_interact PF15898.5 KFH46686.1 - 5.2 8.0 20.1 10 7.1 8.2 3.2 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4337 PF14235.6 KFH46686.1 - 6.5 6.8 9.0 11 6.1 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fzo_mitofusin PF04799.13 KFH46686.1 - 6.8 6.2 8.0 7.4 6.1 4.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 KFH46686.1 - 9.5 6.9 13.0 1.7 9.3 5.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Pro_isomerase PF00160.21 KFH46687.1 - 1.8e-35 122.5 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.18 KFH46688.1 - 1.6e-15 56.9 0.4 2.9e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46688.1 - 3.1e-07 30.4 8.2 6.5e-07 29.4 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.28 KFH46689.1 - 1.2e-120 403.1 0.0 2e-120 402.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFH46689.1 - 6.2e-54 182.6 0.1 1e-53 181.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFH46689.1 - 2.8e-33 114.2 0.5 6.1e-33 113.1 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFH46689.1 - 6.6e-29 100.9 0.2 1.3e-28 99.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFH46689.1 - 2.6e-21 75.7 0.3 7.1e-21 74.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFH46689.1 - 1.5e-20 73.1 0.0 3.1e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFH46689.1 - 2.2e-11 44.1 1.2 8e-11 42.3 1.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L22e PF01776.17 KFH46689.1 - 0.17 12.3 2.9 0.19 12.1 0.0 2.6 3 0 0 3 3 3 0 Ribosomal L22e protein family DUF3318 PF11780.8 KFH46691.1 - 0.014 15.4 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF2470 PF10615.9 KFH46692.1 - 8.7e-19 67.9 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PIGA PF08288.12 KFH46693.1 - 1.1e-47 160.5 1.3 1.1e-47 160.5 1.3 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KFH46693.1 - 5.1e-27 94.5 0.0 9.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH46693.1 - 7.3e-24 84.7 0.1 1.7e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFH46693.1 - 6.7e-23 81.5 0.4 1.1e-22 80.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFH46693.1 - 3.8e-11 43.7 0.0 9.2e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFH46693.1 - 0.00013 22.3 0.0 0.001 19.4 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KFH46693.1 - 0.00024 21.1 0.1 0.00044 20.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like PRCC PF10253.9 KFH46694.1 - 0.21 12.3 2.9 0.3 11.8 2.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 KFH46695.1 - 4.4e-32 111.4 56.5 1.7e-28 99.6 48.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH46695.1 - 3.3e-08 32.4 19.5 1.1e-07 30.7 9.3 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Helicase_C PF00271.31 KFH46696.1 - 3.2e-18 66.1 0.0 3.1e-15 56.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFH46696.1 - 2.8e-13 50.4 1.1 7.3e-13 49.0 1.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 KFH46696.1 - 0.00096 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.32 KFH46697.1 - 2.7e-12 47.0 9.1 0.0012 19.6 0.0 8.3 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KFH46697.1 - 0.41 11.2 3.9 9.3 6.9 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain Ribosomal_S6e PF01092.19 KFH46698.1 - 2.3e-58 195.6 0.1 4.7e-58 194.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e HSP70 PF00012.20 KFH46699.1 - 7.6e-259 859.9 4.7 8.6e-259 859.7 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFH46699.1 - 2.2e-17 62.9 0.0 3.7e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFH46699.1 - 0.00066 19.5 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFH46699.1 - 0.016 15.6 1.8 8.8 6.8 0.0 3.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 KFH46699.1 - 0.053 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 KFH46699.1 - 0.074 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PMBR PF09373.10 KFH46699.1 - 0.39 11.0 1.2 0.76 10.0 0.1 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat GCN5L1 PF06320.13 KFH46701.1 - 2.6e-15 56.5 0.5 3.7e-15 56.1 0.5 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) PV-1 PF06637.11 KFH46701.1 - 0.13 11.0 1.8 0.16 10.7 1.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4956 PF16316.5 KFH46702.1 - 0.28 10.8 0.2 0.46 10.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) RNA12 PF10443.9 KFH46703.1 - 1e-158 528.7 2.4 1.6e-158 528.1 0.3 2.0 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 KFH46703.1 - 7.3e-07 28.9 0.0 3.3e-06 26.8 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KFH46703.1 - 1.6e-05 25.0 0.1 0.00024 21.1 0.1 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 KFH46703.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) AAA_16 PF13191.6 KFH46703.1 - 0.016 15.6 0.1 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain HMMR_N PF15905.5 KFH46703.1 - 0.056 12.9 1.6 0.094 12.2 1.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PPTA PF01239.22 KFH46703.1 - 0.086 12.6 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat BLOC1_2 PF10046.9 KFH46703.1 - 0.5 10.7 3.1 3.1 8.2 1.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HR1 PF02185.16 KFH46703.1 - 1.1 9.4 3.5 2.7 8.2 3.5 1.6 1 0 0 1 1 1 0 Hr1 repeat Ribosomal_S5_C PF03719.15 KFH46706.1 - 7.7e-17 60.5 0.0 2.1e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFH46706.1 - 1.1e-16 60.6 0.0 2.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S8e PF01201.22 KFH46707.1 - 9.2e-56 187.8 2.0 1.1e-55 187.6 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.6 KFH46707.1 - 0.076 14.0 1.0 0.076 14.0 1.0 2.1 2 0 0 2 2 2 0 Small acidic protein family NifU PF01106.17 KFH46709.1 - 4.2e-27 94.1 0.1 7.1e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KFH46709.1 - 4.6e-27 93.9 0.0 2.4e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 KFH46709.1 - 0.0013 18.7 0.6 0.009 16.1 0.3 2.1 2 0 0 2 2 2 1 Bacterial membrane-spanning protein N-terminus CENP-F_leu_zip PF10473.9 KFH46710.1 - 0.007 16.4 16.3 0.007 16.4 16.3 8.3 6 2 5 11 11 11 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.10 KFH46710.1 - 0.007 16.6 7.2 0.007 16.6 7.2 9.2 9 2 1 10 10 10 1 Cortexillin I, coiled coil Lip_prot_lig_C PF10437.9 KFH46710.1 - 0.99 9.4 5.2 15 5.6 0.0 4.6 4 1 1 5 5 5 0 Bacterial lipoate protein ligase C-terminus MIF4G PF02854.19 KFH46710.1 - 2.5 7.7 6.6 0.44 10.1 0.1 3.0 3 0 0 3 3 3 0 MIF4G domain DUF2009 PF09418.10 KFH46710.1 - 4.2 6.3 13.2 0.17 10.9 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) DUF2730 PF10805.8 KFH46710.1 - 5.2 7.2 32.5 1.6 8.9 1.1 8.1 7 2 1 8 8 8 0 Protein of unknown function (DUF2730) Met_10 PF02475.16 KFH46711.1 - 4.4e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein GDPD PF03009.17 KFH46713.1 - 4.4e-61 206.9 0.0 1.1e-60 205.5 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KFH46713.1 - 1.2e-27 96.3 0.1 1.7e-08 34.9 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH46713.1 - 2.3e-26 91.8 4.5 1.2e-09 38.5 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH46713.1 - 3.8e-19 68.5 0.8 2.9e-09 37.0 0.1 5.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 KFH46713.1 - 2.7e-18 67.1 18.2 1.5e-11 44.9 0.2 4.7 3 2 1 4 4 4 3 SPX domain Ank_3 PF13606.6 KFH46713.1 - 2.7e-16 58.0 3.3 0.0032 17.8 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KFH46713.1 - 3.6e-15 55.6 6.5 0.00069 19.9 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat ORC6 PF05460.13 KFH46714.1 - 4.4e-33 115.0 0.2 1.1e-32 113.7 0.1 1.7 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) WW PF00397.26 KFH46715.1 - 8.4e-11 41.8 0.2 1.7e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 WW domain Alfin PF12165.8 KFH46716.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Alfin ATP19 PF11022.8 KFH46716.1 - 0.21 12.0 0.2 22 5.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase subunit K Tetraspanin PF00335.20 KFH46718.1 - 1.8e-06 27.9 0.1 4.7e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Tetraspanin family zf-HIT PF04438.16 KFH46719.1 - 6.8e-10 38.6 13.0 1e-09 38.1 13.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KFH46719.1 - 0.00013 22.0 7.9 0.00021 21.3 7.9 1.3 1 0 0 1 1 1 1 MYND finger Neugrin PF06413.11 KFH46720.1 - 5.5e-10 39.6 1.1 5.5e-10 39.6 1.1 2.3 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KFH46720.1 - 1.4e-05 25.4 5.5 1.4e-05 25.4 5.5 2.6 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 PBP_sp32 PF07222.12 KFH46720.1 - 2.5 7.5 13.8 0.68 9.4 3.3 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Ctf8 PF09696.10 KFH46721.1 - 1.4e-39 135.7 0.1 9.7e-39 132.9 0.1 1.9 1 1 0 1 1 1 1 Ctf8 Cm_res_leader PF08077.11 KFH46721.1 - 0.0067 16.3 0.1 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Chloramphenicol resistance gene leader peptide Smg4_UPF3 PF03467.15 KFH46722.1 - 1.1e-49 168.8 0.0 1.1e-49 168.8 0.0 3.1 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KFH46722.1 - 1.1e-07 31.5 0.0 4.5e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_C PF02752.22 KFH46723.1 - 1.2e-14 54.9 0.0 6.7e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CENP-C_C PF11699.8 KFH46724.1 - 3.9e-33 113.5 0.2 5.8e-33 113.0 0.2 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KFH46724.1 - 5e-28 98.5 9.8 5e-28 98.5 9.8 3.2 1 1 1 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KFH46724.1 - 1.3e-06 28.0 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Lactamase_B PF00753.27 KFH46724.1 - 0.022 14.8 0.1 0.054 13.5 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Cupin_1 PF00190.22 KFH46724.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF2236 PF09995.9 KFH46725.1 - 2.1e-33 116.5 5.5 3.2e-33 115.8 5.5 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FUSC_2 PF13515.6 KFH46725.1 - 0.41 10.8 4.9 0.17 12.0 0.5 2.4 3 0 0 3 3 3 0 Fusaric acid resistance protein-like Colicin_V PF02674.16 KFH46725.1 - 2.1 8.3 5.7 66 3.5 0.2 3.2 3 0 0 3 3 3 0 Colicin V production protein TRF PF08558.10 KFH46726.1 - 4.7e-06 26.4 0.0 9.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFH46726.1 - 6.8e-05 23.0 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RHD3 PF05879.12 KFH46727.1 - 0 1045.9 0.0 0 1045.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KFH46727.1 - 7.2e-08 32.0 0.1 1.1e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KFH46727.1 - 4.5e-06 26.8 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KFH46727.1 - 4.6e-05 23.7 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFH46727.1 - 9.5e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFH46727.1 - 0.026 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Septin DUF3693 PF12472.8 KFH46727.1 - 0.053 13.2 0.1 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 Phage related protein Mito_carr PF00153.27 KFH46728.1 - 2.7e-31 107.3 0.7 3.8e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KFH46729.1 - 0.0023 18.3 0.4 0.0085 16.5 0.4 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH46729.1 - 0.24 12.3 0.4 0.24 12.3 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 KFH46730.1 - 1.7e-07 30.9 0.0 0.0008 18.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46730.1 - 3.2e-05 23.3 0.0 0.00067 19.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Tubulin PF00091.25 KFH46731.1 - 5e-67 225.9 0.0 6.9e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFH46731.1 - 2.1e-48 163.7 0.0 3.3e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFH46731.1 - 0.0043 16.7 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Ribosomal_L15e PF00827.17 KFH46732.1 - 1.4e-89 298.9 10.0 1.7e-89 298.7 10.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-ZPR1 PF03367.13 KFH46733.1 - 6.6e-115 380.3 0.0 4.8e-59 198.8 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.7 KFH46733.1 - 0.37 10.8 9.1 23 5.1 0.1 3.7 3 1 0 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFH46733.1 - 0.48 10.4 5.6 4.2 7.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbons Peptidase_M16 PF00675.20 KFH46734.1 - 3.9e-16 59.4 0.1 7.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFH46734.1 - 2.4e-14 53.7 0.0 3.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain tRNA_int_end_N2 PF12928.7 KFH46736.1 - 2.4e-22 78.9 0.2 4.8e-22 77.9 0.2 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KFH46736.1 - 0.0038 16.9 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Diphthamide_syn PF01866.17 KFH46738.1 - 2.5e-115 385.1 0.0 3.3e-115 384.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3425 PF11905.8 KFH46739.1 - 5.9e-17 61.8 0.2 1.1e-16 61.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CFEM PF05730.11 KFH46741.1 - 1.5e-11 44.2 9.6 2.3e-11 43.6 9.6 1.3 1 0 0 1 1 1 1 CFEM domain SymE_toxin PF08845.10 KFH46741.1 - 0.021 14.9 0.0 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system Rad51 PF08423.11 KFH46742.1 - 7.7e-44 149.9 0.0 9.9e-43 146.2 0.0 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFH46742.1 - 9.5e-10 38.4 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFH46742.1 - 7e-06 25.7 0.7 0.00033 20.2 0.7 2.2 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFH46742.1 - 0.00032 20.1 0.2 0.00053 19.4 0.2 1.5 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 KFH46742.1 - 0.042 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH46742.1 - 0.05 13.5 0.2 0.17 11.8 0.2 1.8 1 1 0 1 1 1 0 NACHT domain SPX PF03105.19 KFH46742.1 - 0.13 12.1 1.3 0.2 11.6 1.3 1.3 1 0 0 1 1 1 0 SPX domain RsgA_GTPase PF03193.16 KFH46743.1 - 0.0048 16.8 0.6 0.012 15.5 0.5 1.7 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KFH46743.1 - 0.0074 16.4 0.3 0.013 15.5 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFH46743.1 - 0.0081 16.7 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Ras PF00071.22 KFH46743.1 - 0.013 15.1 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.6 KFH46743.1 - 0.028 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KFH46743.1 - 0.06 12.4 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TrwB_AAD_bind PF10412.9 KFH46743.1 - 0.069 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 KFH46743.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFH46743.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFH46743.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KFH46743.1 - 0.16 11.7 0.2 0.32 10.7 0.1 1.5 1 1 0 2 2 2 0 AAA domain Rpr2 PF04032.16 KFH46744.1 - 1.7e-17 63.5 0.2 1.7e-17 63.5 0.2 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1178 PF06676.11 KFH46744.1 - 0.32 11.4 11.2 0.51 10.7 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Carn_acyltransf PF00755.20 KFH46746.1 - 3.2e-200 666.7 0.0 1.7e-199 664.3 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF908 PF06012.12 KFH46747.1 - 3.8e-123 411.5 0.1 3.8e-123 411.5 0.1 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 KFH46747.1 - 5e-123 410.7 0.0 5e-123 410.7 0.0 5.8 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.25 KFH46747.1 - 4.3e-95 318.7 0.0 7.2e-95 318.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KFH46747.1 - 7.6e-19 66.5 15.8 1e-07 31.1 0.1 3.9 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KFH46747.1 - 0.063 13.2 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 UBA/TS-N domain V-ATPase_H_N PF03224.14 KFH46747.1 - 0.15 11.3 4.8 0.25 10.6 1.4 3.1 3 0 0 3 3 3 0 V-ATPase subunit H SOG2 PF10428.9 KFH46748.1 - 2.5e-76 257.9 1.3 6.7e-53 180.6 0.1 4.6 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 KFH46748.1 - 5.5e-20 70.9 1.1 2.3e-10 40.1 0.2 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFH46748.1 - 1e-13 51.2 1.9 3.2e-05 24.2 0.2 3.9 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH46748.1 - 0.00044 20.4 3.9 6.9 7.6 0.1 6.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFH46748.1 - 0.0015 18.4 3.6 13 6.1 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich repeat DUF2408 PF10303.9 KFH46748.1 - 0.0022 18.6 0.1 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) DEAD PF00270.29 KFH46749.1 - 4.5e-33 114.5 0.0 3.2e-30 105.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH46749.1 - 3.7e-22 78.8 0.0 1.7e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH46749.1 - 5.1e-08 33.1 0.0 2.2e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFH46749.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Aldose_epim PF01263.20 KFH46750.1 - 7e-49 166.7 0.9 9.3e-49 166.3 0.9 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase CHB_HEX_C_1 PF13290.6 KFH46750.1 - 0.99 9.5 7.4 1.1 9.4 2.1 3.0 1 1 1 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain UPF0242 PF06785.11 KFH46752.1 - 9.2e-05 22.6 0.9 9.2e-05 22.6 0.9 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KFH46752.1 - 0.0015 18.6 8.8 0.0015 18.6 8.8 2.8 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KFH46752.1 - 0.0046 15.2 10.4 0.0084 14.3 10.4 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 KFH46752.1 - 0.0046 16.5 7.1 0.0046 16.5 7.1 1.7 1 1 1 2 2 2 1 Golgin subfamily A member 5 PI3K_1B_p101 PF10486.9 KFH46752.1 - 0.013 13.3 4.7 0.015 13.1 4.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Csm1_N PF18504.1 KFH46752.1 - 0.027 14.8 7.3 0.027 14.8 7.3 2.0 2 0 0 2 2 1 0 Csm1 N-terminal domain Mating_N PF12731.7 KFH46752.1 - 0.049 13.7 0.3 0.097 12.8 0.3 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 DUF2353 PF09789.9 KFH46752.1 - 0.059 12.7 17.3 0.12 11.7 17.3 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 KFH46752.1 - 0.11 12.8 18.8 0.74 10.0 6.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KFH46752.1 - 0.16 12.0 3.4 0.27 11.2 3.4 1.4 1 1 0 1 1 1 0 Laminin Domain II Prominin PF05478.11 KFH46752.1 - 0.17 9.8 1.1 0.23 9.4 1.1 1.1 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 KFH46752.1 - 0.23 11.7 19.8 0.57 10.4 17.9 2.1 1 1 1 2 2 1 0 JNK_SAPK-associated protein-1 DUF3810 PF12725.7 KFH46752.1 - 0.4 10.0 4.9 0.24 10.7 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) V_ATPase_I PF01496.19 KFH46752.1 - 0.85 7.5 6.0 1.1 7.1 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 KFH46752.1 - 1.3 8.3 10.3 0.32 10.3 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Med9 PF07544.13 KFH46752.1 - 1.5 9.0 12.3 0.31 11.2 1.1 2.4 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 KFH46752.1 - 2.4 7.0 17.3 0.022 13.7 8.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein STAT_alpha PF01017.20 KFH46752.1 - 3.1 7.7 10.5 0.29 11.0 5.2 1.7 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF4407 PF14362.6 KFH46752.1 - 3.6 6.9 16.6 0.57 9.5 7.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Auts2 PF15336.6 KFH46752.1 - 4.4 7.4 18.4 0.069 13.3 11.0 1.8 2 1 0 2 2 2 0 Autism susceptibility gene 2 protein Exonuc_VII_L PF02601.15 KFH46752.1 - 4.5 6.8 7.6 6.7 6.2 7.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ima1_N PF09779.9 KFH46752.1 - 6.2 7.7 8.6 2.3 9.1 4.1 2.2 2 0 0 2 2 2 0 Ima1 N-terminal domain YabA PF06156.13 KFH46752.1 - 6.3 7.5 10.1 3.9 8.2 5.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Steroid_dh PF02544.16 KFH46753.1 - 2.3e-30 105.6 0.5 3.3e-30 105.0 0.1 1.4 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFH46753.1 - 0.00019 21.0 0.3 0.00044 19.8 0.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Bromodomain PF00439.25 KFH46754.1 - 7.3e-05 22.8 0.0 0.0003 20.8 0.0 2.0 1 1 0 1 1 1 1 Bromodomain DUF3128 PF11326.8 KFH46755.1 - 2.9e-27 94.9 1.5 5.8e-27 93.9 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) PUF PF00806.19 KFH46756.1 - 3e-58 190.3 13.3 2e-07 30.3 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.11 KFH46756.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Tsc35 PF15079.6 KFH46757.1 - 0.041 13.5 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Testis-specific protein 35 Rgp1 PF08737.10 KFH46758.1 - 6.6e-155 516.4 0.0 4e-154 513.8 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 KFH46758.1 - 0.00058 19.9 0.3 0.0023 18.0 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFH46758.1 - 0.024 15.1 0.2 0.45 11.0 0.0 2.7 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Spt20 PF12090.8 KFH46758.1 - 0.32 10.6 5.9 0.55 9.8 5.9 1.3 1 0 0 1 1 1 0 Spt20 family Epimerase PF01370.21 KFH46759.1 - 3.1e-19 69.4 0.0 4.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH46759.1 - 3.4e-14 52.5 0.0 5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFH46759.1 - 1.1e-11 44.4 0.0 3.2e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFH46759.1 - 7.3e-10 38.8 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFH46759.1 - 1.4e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFH46759.1 - 5.1e-07 29.1 0.0 7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFH46759.1 - 2.6e-05 23.8 0.1 4.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46759.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFH46759.1 - 0.0003 21.3 0.0 0.0007 20.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 KFH46759.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KFH46759.1 - 0.023 14.3 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family OAD_gamma PF04277.13 KFH46760.1 - 0.015 15.9 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SH PF01445.17 KFH46760.1 - 0.033 14.1 0.2 0.048 13.6 0.2 1.1 1 0 0 1 1 1 0 Viral small hydrophobic protein UPF0542 PF15086.6 KFH46760.1 - 0.054 13.4 0.2 0.069 13.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 RabGAP-TBC PF00566.18 KFH46761.1 - 8.5e-49 166.1 0.4 8.5e-49 166.1 0.4 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 KFH46761.1 - 0.0012 19.1 20.1 0.0012 19.1 20.1 3.2 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KFH46761.1 - 0.0057 16.8 6.0 0.0057 16.8 6.0 3.6 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 KFH46761.1 - 0.059 13.6 0.4 0.059 13.6 0.4 4.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KFH46761.1 - 0.67 10.4 14.7 5.5 7.5 1.5 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 KFH46761.1 - 1.9 8.5 38.3 0.31 11.1 11.1 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFH46761.1 - 2 8.5 16.4 1.5 8.9 5.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KFH46761.1 - 3.1 7.2 40.0 1.7 8.1 28.2 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Z1 PF10593.9 KFH46761.1 - 3.5 7.0 7.3 9.3 5.7 7.3 1.7 1 0 0 1 1 1 0 Z1 domain ATP-synt_ab PF00006.25 KFH46762.1 - 3e-65 219.8 0.0 4.2e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFH46762.1 - 2.3e-05 24.8 1.8 0.043 14.3 0.1 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KFH46762.1 - 0.084 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DASH_Dad3 PF08656.10 KFH46763.1 - 9.5e-34 115.3 0.1 1.1e-33 115.1 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 YopE PF03545.13 KFH46763.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) APO_RNA-bind PF05634.11 KFH46763.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding BshC PF10079.9 KFH46763.1 - 0.15 10.8 0.1 0.16 10.6 0.1 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC EF-hand_6 PF13405.6 KFH46764.1 - 7.1e-07 28.7 1.1 0.0055 16.5 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFH46764.1 - 3.2e-05 23.2 0.1 0.00039 19.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFH46764.1 - 4.1e-05 24.0 0.3 4.1e-05 24.0 0.3 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFH46764.1 - 0.00049 19.5 0.3 0.02 14.4 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFH46764.1 - 0.14 12.0 0.3 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair KCNQ2_u3 PF16642.5 KFH46765.1 - 0.007 17.3 7.4 0.0089 17.0 3.8 2.5 1 1 2 3 3 3 1 Unstructured region on Potassium channel subunit alpha KvLQT2 adh_short_C2 PF13561.6 KFH46766.1 - 3.6e-57 193.6 2.2 4.3e-57 193.4 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46766.1 - 6.9e-50 169.2 0.4 8.5e-50 168.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46766.1 - 7.4e-08 32.5 1.0 2.2e-07 31.0 1.0 1.7 1 1 0 1 1 1 1 KR domain Pro_isomerase PF00160.21 KFH46768.1 - 2.4e-43 148.2 0.0 4.6e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phosphatase PF15698.5 KFH46768.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatase RasGEF PF00617.19 KFH46769.1 - 3.8e-46 157.5 0.1 6.2e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFH46769.1 - 4.9e-14 52.4 0.1 5.9e-13 49.0 0.0 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif Putative_PNPOx PF01243.20 KFH46770.1 - 0.092 13.0 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HMGL-like PF00682.19 KFH46771.1 - 4.1e-43 147.9 0.0 4.4e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 HMGL-like ketoacyl-synt PF00109.26 KFH46772.1 - 0.025 14.2 0.6 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain PPR_1 PF12854.7 KFH46772.1 - 0.078 12.7 2.0 0.88 9.3 0.3 3.0 1 1 1 2 2 2 0 PPR repeat PPR_3 PF13812.6 KFH46772.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain CcdA PF07362.12 KFH46772.1 - 0.28 11.6 2.5 44 4.6 0.0 4.1 4 0 0 4 4 4 0 Post-segregation antitoxin CcdA Metallophos PF00149.28 KFH46773.1 - 7.9e-33 114.7 0.0 3.4e-28 99.6 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFH46773.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain adh_short PF00106.25 KFH46774.1 - 6.4e-38 130.2 0.2 9.2e-38 129.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46774.1 - 1.7e-30 106.3 0.1 2.6e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH46774.1 - 3e-10 40.3 3.9 3.4e-09 36.9 3.9 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH46774.1 - 0.0058 16.1 0.1 0.015 14.7 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KFH46774.1 - 0.019 14.8 0.2 0.062 13.1 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 KFH46774.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RNase_HII PF01351.18 KFH46775.1 - 4.1e-47 160.6 0.0 6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Adeno_VII PF03228.14 KFH46775.1 - 0.29 11.8 0.8 1.8 9.2 0.1 2.2 2 0 0 2 2 2 0 Adenoviral core protein VII TFIIA PF03153.13 KFH46776.1 - 1.2 9.0 11.5 1.5 8.7 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M41 PF01434.18 KFH46777.1 - 1.7e-52 178.1 0.7 2.9e-52 177.3 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFH46777.1 - 2.1e-43 147.9 0.0 4.3e-43 146.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH46777.1 - 4.9e-07 29.5 0.1 9.8e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFH46777.1 - 1.1e-06 28.7 0.1 5.4e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFH46777.1 - 1.2e-05 25.8 0.2 6.1e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFH46777.1 - 6.1e-05 23.2 0.1 0.00052 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFH46777.1 - 0.0001 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KFH46777.1 - 0.00032 20.5 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH46777.1 - 0.0011 19.3 0.1 0.052 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFH46777.1 - 0.0083 15.9 0.1 0.022 14.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFH46777.1 - 0.015 14.7 0.2 0.039 13.3 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFH46777.1 - 0.029 13.9 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFH46777.1 - 0.044 13.4 1.0 1.4 8.5 0.2 2.5 1 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KFH46777.1 - 0.051 13.7 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KFH46777.1 - 0.057 13.4 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFH46777.1 - 0.08 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KFH46777.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_28 PF13521.6 KFH46777.1 - 0.084 13.1 0.1 0.24 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KFH46777.1 - 0.16 11.4 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KFH46777.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH46777.1 - 0.21 11.5 1.9 1.5 8.7 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 KFH46777.1 - 0.28 10.4 1.4 0.7 9.1 0.4 2.0 1 1 1 2 2 2 0 Zeta toxin SUIM_assoc PF16619.5 KFH46778.1 - 0.15 12.1 10.0 0.48 10.5 10.0 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Calcipressin PF04847.12 KFH46779.1 - 2.9e-46 157.5 0.1 3.7e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 KFH46779.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF866 PF05907.13 KFH46781.1 - 1.4e-67 226.4 0.4 1.6e-67 226.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Rubredoxin_2 PF18073.1 KFH46781.1 - 0.059 13.1 2.0 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4379 PF14311.6 KFH46781.1 - 0.1 13.0 1.0 0.1 13.0 1.0 2.2 1 1 1 2 2 2 0 Probable Zinc-ribbon domain RNA_pol_Rpc82 PF05645.13 KFH46782.1 - 9.6e-48 163.2 0.6 5.3e-47 160.8 0.1 2.5 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KFH46782.1 - 1.4e-16 60.3 2.4 4.2e-13 49.2 0.2 4.0 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KFH46782.1 - 1.2e-05 25.1 0.7 0.054 13.4 0.0 2.8 2 1 0 2 2 2 2 TFIIE alpha subunit Collagen PF01391.18 KFH46782.1 - 0.094 12.5 3.7 0.22 11.3 3.7 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HSF_DNA-bind PF00447.17 KFH46783.1 - 1.5e-28 99.2 0.3 3.5e-28 98.0 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Pex19 PF04614.12 KFH46783.1 - 0.0015 18.3 0.9 0.0015 18.3 0.9 2.6 3 0 0 3 3 3 1 Pex19 protein family APG6_N PF17675.1 KFH46783.1 - 1 9.9 13.6 7.9 7.0 1.6 3.7 4 0 0 4 4 4 0 Apg6 coiled-coil region UPF0242 PF06785.11 KFH46783.1 - 4.1 7.5 10.9 2 8.5 1.6 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Aldedh PF00171.22 KFH46784.1 - 1.7e-185 617.0 0.1 1.9e-185 616.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFH46784.1 - 0.13 11.7 0.0 6 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glyco_hydro_72 PF03198.14 KFH46785.1 - 1.3e-86 290.8 0.4 2.3e-86 289.9 0.4 1.3 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFH46785.1 - 0.028 13.8 0.3 0.31 10.4 0.3 2.2 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KFH46785.1 - 0.029 13.5 0.1 0.051 12.7 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pga1 PF10333.9 KFH46786.1 - 0.049 13.5 0.3 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Pep_deformylase PF01327.21 KFH46787.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Polypeptide deformylase PSP1 PF04468.12 KFH46788.1 - 3e-28 97.9 1.5 6.3e-28 96.9 1.5 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF5094 PF17015.5 KFH46788.1 - 0.033 14.3 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Orthopox_F8 PF05886.11 KFH46788.1 - 4.4 7.5 5.2 15 5.8 1.5 3.2 3 0 0 3 3 3 0 Orthopoxvirus F8 protein LsmAD PF06741.13 KFH46789.1 - 2.6e-27 95.1 3.3 2.6e-27 95.1 3.3 2.4 2 0 0 2 2 2 1 LsmAD domain LRR_6 PF13516.6 KFH46790.1 - 0.12 12.5 7.4 65 4.0 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat SHMT PF00464.19 KFH46791.1 - 1.3e-197 656.2 0.0 1.5e-197 656.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KFH46791.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Histone PF00125.24 KFH46792.1 - 3.4e-35 121.2 0.2 4e-35 121.0 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFH46792.1 - 3.3e-06 27.4 0.0 4.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFH46792.1 - 1.7e-05 24.9 0.1 2.2e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFH46792.1 - 0.0017 18.6 0.0 0.0021 18.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFH46792.1 - 0.015 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFH46792.1 - 0.027 14.5 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Gcn1_N PF12074.8 KFH46793.1 - 2.2e-107 359.5 0.6 4.9e-106 355.0 0.1 3.7 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KFH46793.1 - 1.4e-38 127.6 26.4 0.017 15.3 0.0 21.8 25 1 1 26 26 22 8 HEAT repeat HEAT_EZ PF13513.6 KFH46793.1 - 8.3e-36 122.0 38.5 1.9e-07 31.4 0.1 19.7 15 4 7 22 22 19 6 HEAT-like repeat HEAT_2 PF13646.6 KFH46793.1 - 1.4e-27 95.9 49.4 8e-06 26.2 0.2 17.3 14 5 5 19 19 18 9 HEAT repeats Cnd1 PF12717.7 KFH46793.1 - 8.3e-18 65.0 11.6 0.58 10.2 0.2 12.2 8 3 4 13 13 13 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFH46793.1 - 5.9e-14 52.4 0.0 0.088 13.4 0.0 10.2 9 2 2 11 11 9 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KFH46793.1 - 1e-12 48.6 1.4 0.00016 21.9 0.0 6.9 7 1 1 8 8 8 3 Parkin co-regulated protein CLASP_N PF12348.8 KFH46793.1 - 5.2e-12 45.8 0.0 0.025 14.1 0.0 6.6 6 1 2 8 8 7 4 CLASP N terminal DUF937 PF06078.11 KFH46793.1 - 8.4e-10 39.4 0.3 0.23 12.1 0.0 7.6 6 3 1 7 7 6 1 Bacterial protein of unknown function (DUF937) MMS19_C PF12460.8 KFH46793.1 - 4.8e-08 32.5 5.1 0.028 13.5 0.1 6.9 7 1 1 8 8 8 2 RNAPII transcription regulator C-terminal UME PF08064.13 KFH46793.1 - 6.6e-08 32.4 0.2 3.1 7.8 0.0 7.6 6 3 3 9 9 8 1 UME (NUC010) domain TIP120 PF08623.10 KFH46793.1 - 1.2e-07 31.6 0.0 0.042 13.6 0.0 7.2 7 1 1 8 8 8 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 KFH46793.1 - 6.2e-07 28.3 13.0 0.055 12.0 0.2 8.2 7 3 1 8 8 8 2 Adaptin N terminal region DUF3385 PF11865.8 KFH46793.1 - 1.2e-05 25.3 0.1 0.26 11.2 0.0 6.3 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KFH46793.1 - 0.00013 21.6 3.2 0.99 8.9 0.0 6.6 7 1 0 7 7 7 1 Tti2 family DRIM PF07539.12 KFH46793.1 - 0.0012 17.2 12.1 0.054 11.8 0.1 5.6 5 1 1 6 6 6 1 Down-regulated in metastasis TFCD_C PF12612.8 KFH46793.1 - 0.002 18.0 2.6 0.027 14.3 0.0 4.2 4 1 0 4 4 3 1 Tubulin folding cofactor D C terminal RasGEF_N_2 PF14663.6 KFH46793.1 - 0.0039 17.6 5.7 8.6 6.8 0.0 6.6 8 0 0 8 8 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ecm29 PF13001.7 KFH46793.1 - 0.0087 14.8 11.2 0.66 8.6 0.0 6.5 7 2 1 8 8 8 1 Proteasome stabiliser FANCI_S2 PF14676.6 KFH46793.1 - 0.022 15.0 1.2 2.8 8.2 0.1 4.4 4 0 0 4 4 4 0 FANCI solenoid 2 NusB PF01029.18 KFH46793.1 - 0.034 14.4 0.6 7.6 6.8 0.0 3.8 3 0 0 3 3 2 0 NusB family Vitellogenin_N PF01347.22 KFH46793.1 - 0.049 12.0 0.0 7.4 4.8 0.0 3.6 5 0 0 5 5 5 0 Lipoprotein amino terminal region HBS1_N PF08938.10 KFH46793.1 - 0.049 13.9 1.0 0.48 10.7 0.0 3.2 2 0 0 2 2 2 0 HBS1 N-terminus Ipi1_N PF12333.8 KFH46793.1 - 0.051 14.2 3.7 1.1 9.9 0.1 4.2 4 0 0 4 4 3 0 Rix1 complex component involved in 60S ribosome maturation Harakiri PF15196.6 KFH46793.1 - 0.058 13.8 0.0 0.24 11.9 0.0 2.1 1 0 0 1 1 1 0 Activator of apoptosis harakiri DUF3730 PF12530.8 KFH46793.1 - 0.068 12.7 4.0 6.2 6.3 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3730) RIX1 PF08167.12 KFH46793.1 - 0.11 12.2 7.6 0.21 11.3 0.5 4.5 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis MbeD_MobD PF04899.12 KFH46793.1 - 0.87 9.7 0.0 0.87 9.7 0.0 2.9 3 0 0 3 3 2 0 MbeD/MobD like Arm PF00514.23 KFH46793.1 - 1.9 8.6 14.2 17 5.7 0.1 8.6 11 0 0 11 11 8 0 Armadillo/beta-catenin-like repeat FtsJ PF01728.19 KFH46794.1 - 4.1e-42 144.3 0.0 5.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_fiss_reg PF05308.11 KFH46794.1 - 0.11 12.6 1.0 0.16 12.0 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.18 KFH46795.1 - 1.3e-22 80.1 0.0 2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46795.1 - 6.8e-06 26.1 15.4 1.2e-05 25.4 15.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb1_5 PF04998.17 KFH46796.1 - 7e-87 291.2 0.0 1.2e-86 290.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFH46796.1 - 2.4e-68 229.6 0.4 4.8e-68 228.6 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KFH46796.1 - 3.2e-35 122.0 1.0 8.3e-34 117.3 0.3 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KFH46796.1 - 4.2e-35 121.0 0.0 1.2e-34 119.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFH46796.1 - 4.2e-18 65.3 0.0 1.7e-17 63.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_hydro_6 PF01341.17 KFH46797.1 - 7e-96 321.5 0.1 9.2e-96 321.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Catalase PF00199.19 KFH46799.1 - 7.3e-172 571.8 0.5 9.4e-172 571.4 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFH46799.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KFH46799.1 - 3e-12 46.5 0.2 1.3e-11 44.4 0.2 2.0 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KFH46799.1 - 9.5e-11 41.8 0.2 2.9e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family zf-C2H2 PF00096.26 KFH46800.1 - 3.8e-14 52.2 21.0 2.3e-05 24.6 2.2 4.0 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH46800.1 - 2.9e-08 33.8 24.2 0.00062 20.4 0.4 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH46800.1 - 0.023 15.1 1.8 0.023 15.1 1.8 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KFH46800.1 - 0.055 13.4 1.2 0.16 11.9 1.2 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFH46800.1 - 0.074 13.1 0.2 0.074 13.1 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFH46800.1 - 0.077 12.8 0.2 0.077 12.8 0.2 3.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFH46800.1 - 0.15 12.4 7.7 0.4 11.0 7.1 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-BED PF02892.15 KFH46800.1 - 0.23 11.5 10.8 0.35 10.9 5.6 2.6 2 0 0 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 KFH46800.1 - 2.4 8.9 12.3 1.7 9.4 7.4 2.7 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.12 KFH46800.1 - 3.3 7.8 6.9 8.9 6.4 0.1 3.1 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger NAD_binding_6 PF08030.12 KFH46801.1 - 3.7e-17 62.9 0.0 5.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFH46801.1 - 6e-17 61.9 13.0 6e-17 61.9 13.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFH46801.1 - 8.7e-09 35.4 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain TAF8_C PF10406.9 KFH46802.1 - 3e-17 62.9 0.2 5.9e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KFH46802.1 - 2.6e-06 27.4 0.0 2.5e-05 24.2 0.0 2.4 3 0 0 3 3 3 1 Bromodomain associated Glyoxalase_6 PF18029.1 KFH46803.1 - 0.0033 18.2 0.0 0.0057 17.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KFH46803.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1330 PF07045.11 KFH46804.1 - 0.02 15.2 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) NmrA PF05368.13 KFH46805.1 - 1.1e-12 48.1 0.1 1.7e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KFH46805.1 - 0.0018 18.2 0.0 0.0047 16.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KFH46805.1 - 0.0023 17.9 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KFH46805.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFH46805.1 - 0.015 14.7 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFH46805.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFH46805.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KFH46805.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KFH46806.1 - 1.8e-11 43.5 0.0 2e-09 36.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PMP1_2 PF08114.11 KFH46807.1 - 0.00075 19.2 2.8 0.0011 18.7 2.8 1.3 1 0 0 1 1 1 1 ATPase proteolipid family DUF3149 PF11346.8 KFH46807.1 - 0.0016 18.1 0.8 0.0021 17.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) LapA_dom PF06305.11 KFH46807.1 - 0.0044 16.8 0.2 0.0055 16.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 KFH46807.1 - 0.037 13.7 0.3 0.037 13.7 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4381 PF14316.6 KFH46807.1 - 0.065 13.5 0.1 0.07 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DHO_dh PF01180.21 KFH46808.1 - 1.5e-20 73.7 0.0 3.9e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KFH46808.1 - 4.9 6.4 7.3 6.5 6.0 7.3 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Forkhead PF00250.18 KFH46809.1 - 1.3e-13 51.0 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFH46809.1 - 7.6e-05 23.0 0.1 0.00016 21.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Glycos_transf_1 PF00534.20 KFH46810.1 - 2.7e-15 56.3 0.0 8e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH46810.1 - 3.8e-15 56.5 0.1 7.9e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KFH46810.1 - 6.3e-05 22.8 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) FUSC-like PF12805.7 KFH46810.1 - 2.6 7.1 4.7 4.6 6.2 4.7 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ER-remodelling PF14755.6 KFH46812.1 - 0.11 12.8 3.3 0.54 10.5 3.7 1.8 2 0 0 2 2 2 0 Intracellular membrane remodeller zf-C2H2 PF00096.26 KFH46813.1 - 6.5e-10 38.9 12.9 0.0072 16.7 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH46813.1 - 0.00014 22.4 9.5 1.1 10.3 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger MFS_1 PF07690.16 KFH46814.1 - 1.3e-37 129.6 44.9 1.3e-37 129.6 44.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46814.1 - 9.1e-10 38.0 10.1 9.1e-10 38.0 10.1 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KFH46814.1 - 0.55 9.5 35.9 0.81 8.9 6.1 2.4 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Ribosomal_L5e PF17144.4 KFH46815.1 - 1.4e-78 262.5 0.2 2.4e-78 261.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFH46815.1 - 1.3e-33 115.8 11.9 1.3e-33 115.8 11.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region UvrD-helicase PF00580.21 KFH46815.1 - 0.0066 16.0 5.0 0.0066 16.0 5.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain TRAP-gamma PF07074.12 KFH46815.1 - 5.2 6.6 5.7 9 5.8 5.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) AMPK1_CBM PF16561.5 KFH46816.1 - 1.5e-21 76.4 0.8 2.9e-21 75.5 0.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KFH46816.1 - 0.0077 16.6 0.7 0.019 15.3 0.3 1.8 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KFH46816.1 - 0.033 14.8 0.7 0.086 13.4 0.7 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Mitochondr_Som1 PF11093.8 KFH46817.1 - 5.4e-19 68.0 0.2 5.9e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 MBOAT PF03062.19 KFH46818.1 - 7.9e-35 120.8 13.9 2.1e-34 119.4 10.1 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KFH46818.1 - 0.0015 18.8 0.2 0.0042 17.3 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DHquinase_I PF01487.15 KFH46819.1 - 2.6e-42 145.6 0.0 4.1e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase DSBA PF01323.20 KFH46820.1 - 7.9e-25 87.8 0.0 9e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TetR_C_20 PF17925.1 KFH46820.1 - 0.055 13.8 0.1 0.089 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Podoplanin PF05808.11 KFH46821.1 - 2.4e-07 31.0 9.9 4.2e-07 30.2 9.9 1.4 1 0 0 1 1 1 1 Podoplanin CFEM PF05730.11 KFH46821.1 - 7.4e-06 26.0 5.3 1.5e-05 25.0 5.3 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KFH46821.1 - 5e-05 22.6 7.5 0.00011 21.5 7.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 KFH46821.1 - 0.0022 18.0 0.1 0.0065 16.4 0.1 1.5 1 1 1 2 2 2 1 Rifin Rax2 PF12768.7 KFH46821.1 - 0.005 16.3 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF347 PF03988.12 KFH46821.1 - 0.0076 16.4 2.1 0.016 15.4 2.1 1.5 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 KFH46821.1 - 0.12 13.3 0.0 0.27 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KFH46821.1 - 0.57 10.0 7.1 0.26 11.1 3.2 2.1 1 1 1 2 2 2 0 Transmembrane protein 51 TMEM154 PF15102.6 KFH46821.1 - 0.86 9.5 13.8 53 3.7 13.8 2.3 1 1 0 1 1 1 0 TMEM154 protein family SMYLE_N PF18615.1 KFH46821.1 - 1 8.8 6.5 0.67 9.5 4.6 1.6 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hamartin PF04388.12 KFH46821.1 - 1.8 7.1 4.8 2.2 6.8 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein Gram_pos_anchor PF00746.21 KFH46821.1 - 2 8.4 5.0 0.83 9.7 0.1 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CDC27 PF09507.10 KFH46821.1 - 2.4 7.5 12.8 3.3 7.0 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 KFH46821.1 - 3 6.6 9.9 4.1 6.1 9.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RCR PF12273.8 KFH46821.1 - 9.1 7.0 6.2 16 6.2 0.0 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Mito_carr PF00153.27 KFH46822.1 - 2.7e-74 245.2 1.6 8.8e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFH46822.1 - 0.00011 21.5 0.3 0.0071 15.5 0.0 3.0 3 1 1 4 4 4 1 Gammaproteobacterial serine protease GAD-like PF08887.11 KFH46822.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain MR_MLE_C PF13378.6 KFH46823.1 - 8.8e-43 146.4 0.0 1.2e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFH46823.1 - 2.8e-09 37.2 0.0 4.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 KFH46823.1 - 0.045 13.1 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase RTA1 PF04479.13 KFH46824.1 - 3.7e-36 124.7 8.5 4.7e-36 124.3 8.5 1.1 1 0 0 1 1 1 1 RTA1 like protein TPPK_C PF12555.8 KFH46824.1 - 6.2 7.0 11.2 7.3 6.7 0.1 3.7 3 1 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Hydrolase_6 PF13344.6 KFH46826.1 - 3.9e-22 78.2 0.0 7.5e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH46826.1 - 1.5e-13 50.6 0.0 6.4e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KFH46826.1 - 0.0062 16.8 0.0 4.1 7.6 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PS_Dcarbxylase PF02666.15 KFH46827.1 - 4.1e-56 189.7 0.0 6.9e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KFH46827.1 - 4.8e-39 132.8 0.0 8.7e-19 67.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KFH46827.1 - 0.0046 16.4 0.1 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFH46827.1 - 0.014 14.8 0.0 0.05 13.1 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KFH46827.1 - 0.14 12.1 0.3 0.87 9.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KFH46827.1 - 0.61 10.6 3.2 3.6 8.1 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair HA2 PF04408.23 KFH46828.1 - 3.6e-15 56.2 0.1 3.6e-15 56.2 0.1 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH46828.1 - 2.3e-13 50.4 0.0 6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH46828.1 - 9e-13 48.4 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KFH46828.1 - 2e-09 37.7 0.0 4.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KFH46828.1 - 4.9e-08 33.3 0.8 1.4e-07 31.9 0.2 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KFH46828.1 - 0.002 18.5 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFH46828.1 - 0.0083 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 KFH46828.1 - 0.023 15.2 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFH46828.1 - 0.048 14.0 1.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KFH46828.1 - 0.055 14.0 4.5 0.92 10.1 2.2 3.8 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 KFH46828.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KFH46828.1 - 0.17 11.8 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase zf-RING_2 PF13639.6 KFH46829.1 - 0.0028 17.9 1.2 0.0028 17.9 1.2 1.5 2 0 0 2 2 2 1 Ring finger domain CENP-T_C PF15511.6 KFH46831.1 - 7.5e-09 35.7 0.1 9.5e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFH46831.1 - 2e-05 25.0 0.1 2.5e-05 24.6 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFH46831.1 - 7.4e-05 22.8 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KFH46831.1 - 0.00016 21.8 0.1 0.00038 20.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFH46831.1 - 0.00037 20.8 0.1 0.00052 20.3 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KFH46831.1 - 0.0084 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit UPF0137 PF03677.13 KFH46831.1 - 0.024 14.5 0.2 0.029 14.2 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Bromo_TP PF07524.13 KFH46831.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 KFH46831.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region 2OG-FeII_Oxy_2 PF13532.6 KFH46832.1 - 6.8e-29 101.5 0.0 1.1e-28 100.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KFH46832.1 - 3.3e-22 79.5 0.1 2.8e-21 76.5 0.1 2.2 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KFH46832.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFH46832.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pectate_lyase PF03211.13 KFH46833.1 - 3.3e-76 255.4 5.1 3.8e-76 255.1 5.1 1.0 1 0 0 1 1 1 1 Pectate lyase Ribosomal_L19e PF01280.20 KFH46834.1 - 2.3e-61 206.1 8.0 2.3e-61 206.1 8.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e DUF4349 PF14257.6 KFH46835.1 - 0.033 13.6 19.7 1.7 8.1 15.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Dynamitin PF04912.14 KFH46835.1 - 0.15 11.3 38.1 1.3 8.2 17.5 2.8 2 1 1 3 3 3 0 Dynamitin Leu_zip PF15294.6 KFH46835.1 - 0.29 10.6 33.7 0.36 10.3 8.2 2.4 1 1 1 2 2 2 0 Leucine zipper Filament PF00038.21 KFH46835.1 - 0.77 9.3 36.0 1.3 8.5 36.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein Lebercilin PF15619.6 KFH46835.1 - 1.2 8.8 48.0 1.2 8.8 14.5 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2703 PF10865.8 KFH46835.1 - 3.3 7.9 5.8 0.71 10.1 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) Spectrin PF00435.21 KFH46835.1 - 4.1 7.9 25.4 1.1 9.8 4.6 3.2 2 1 1 3 3 3 0 Spectrin repeat Golgin_A5 PF09787.9 KFH46835.1 - 4.6 6.6 38.6 7.9 5.8 23.1 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Rootletin PF15035.6 KFH46835.1 - 7.4 6.5 38.7 6.4 6.7 3.9 2.7 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion MFS_1 PF07690.16 KFH46836.1 - 3.3e-08 32.9 24.9 3.3e-08 32.9 24.9 4.9 3 2 2 5 5 5 3 Major Facilitator Superfamily DUF5336 PF17270.2 KFH46836.1 - 0.15 11.7 3.1 0.29 10.7 0.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) PRP3 PF08572.10 KFH46837.1 - 1.5e-73 247.3 1.0 2.4e-73 246.6 1.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFH46837.1 - 2.7e-48 163.8 0.5 2.7e-48 163.8 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF4641 PF15483.6 KFH46837.1 - 0.00077 18.7 1.4 0.0015 17.7 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4641) GET2 PF08690.10 KFH46837.1 - 0.013 15.2 2.2 0.022 14.4 2.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 CBP_BcsG PF11658.8 KFH46837.1 - 0.21 9.9 0.3 2.3 6.5 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG OST3_OST6 PF04756.13 KFH46838.1 - 6.2e-103 344.2 0.0 8e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF2561 PF10812.8 KFH46838.1 - 0.018 15.1 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) CPBP PF02517.16 KFH46838.1 - 0.063 13.6 1.2 0.17 12.3 1.2 1.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease HXXEE PF13787.6 KFH46838.1 - 0.12 13.2 2.8 0.13 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif RNA_pol_Rpb1_5 PF04998.17 KFH46839.1 - 1e-77 261.2 0.1 1.5e-77 260.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KFH46839.1 - 3.4e-77 259.8 0.0 5.1e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFH46839.1 - 8.6e-70 234.3 0.0 1.7e-69 233.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFH46839.1 - 5e-38 130.5 0.0 1e-37 129.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFH46839.1 - 1.4e-30 105.4 0.1 3.5e-30 104.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DZR PF12773.7 KFH46839.1 - 0.55 10.3 5.9 33 4.6 6.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFH46839.1 - 2 8.5 8.5 8.8 6.4 1.3 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 KFH46839.1 - 7 6.2 6.0 5.2 6.6 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain CBP_BcsN PF17038.5 KFH46841.1 - 0.092 12.1 0.0 0.096 12.0 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN WD40 PF00400.32 KFH46842.1 - 4.8e-45 150.6 22.0 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH46842.1 - 9.4e-09 35.5 0.8 0.18 12.2 0.0 4.7 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH46842.1 - 1.3e-05 24.0 6.7 0.069 11.8 0.1 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFH46842.1 - 0.0023 17.0 0.0 7.9 5.3 0.0 3.9 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFH46842.1 - 0.0096 15.3 0.0 0.43 9.9 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFH46842.1 - 0.018 15.0 0.5 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Mpp10 PF04006.12 KFH46843.1 - 6.2e-109 365.2 48.9 1.4e-108 364.0 48.9 1.4 1 1 0 1 1 1 1 Mpp10 protein Spherulin4 PF12138.8 KFH46844.1 - 2.6e-71 240.1 0.0 2.9e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Palm_thioest PF02089.15 KFH46845.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KFH46845.1 - 3.1e-07 30.3 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFH46845.1 - 5.2e-07 29.6 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFH46845.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFH46845.1 - 6.3e-05 23.7 3.9 6.3e-05 23.7 3.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 KFH46845.1 - 0.00028 20.2 0.0 0.00038 19.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 KFH46845.1 - 0.036 13.6 0.0 0.077 12.5 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 2) Hydrolase_4 PF12146.8 KFH46845.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KFH46845.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KFH46845.1 - 0.097 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_MOT1 PF16983.5 KFH46846.1 - 1.8e-62 208.7 31.0 5.1e-35 120.2 8.2 3.2 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily Glyco_hydro_114 PF03537.13 KFH46847.1 - 1.7e-85 286.0 1.0 2.1e-85 285.7 1.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 EPSP_synthase PF00275.20 KFH46849.1 - 6.4e-128 427.0 0.0 1.7e-127 425.6 0.0 1.6 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KFH46849.1 - 6.3e-103 343.5 0.0 1.1e-102 342.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KFH46849.1 - 2.4e-56 191.5 0.0 4e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFH46849.1 - 7.4e-37 126.9 0.0 2.7e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KFH46849.1 - 7.4e-24 83.8 0.0 1e-22 80.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KFH46849.1 - 1.2e-07 31.7 0.0 3.1e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 KFH46849.1 - 0.0001 22.5 0.0 0.0047 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Shikimate_DH PF01488.20 KFH46849.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_24 PF13479.6 KFH46849.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFH46849.1 - 0.03 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH46849.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.21 KFH46850.1 - 1.9e-38 132.3 0.0 1.5e-36 126.1 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH46850.1 - 1.8e-35 123.0 0.0 7.8e-26 91.2 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFH46850.1 - 9.6e-07 28.1 0.4 0.0073 15.4 0.0 2.9 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFH46850.1 - 3e-06 26.6 0.1 7.7e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFH46850.1 - 0.00065 18.9 0.0 0.0038 16.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFH46850.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 KFH46850.1 - 0.018 15.0 0.5 0.23 11.3 0.5 2.2 1 1 0 1 1 1 0 KR domain Pyr_redox_2 PF07992.14 KFH46850.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-MIZ PF02891.20 KFH46851.1 - 4.7e-12 45.5 0.1 1.1e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFH46851.1 - 0.14 12.0 0.5 0.52 10.2 0.5 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KFH46852.1 - 2.2e-07 30.7 2.8 7e-07 29.0 3.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH46852.1 - 4e-07 29.9 2.0 4e-07 29.9 2.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH46852.1 - 4.9e-07 30.0 6.2 9.1e-07 29.1 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFH46852.1 - 4.8e-06 26.3 4.4 1.2e-05 25.1 4.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH46852.1 - 1.4e-05 24.8 6.1 1.8e-05 24.5 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH46852.1 - 2e-05 24.4 3.2 3.8e-05 23.6 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFH46852.1 - 2.1e-05 24.6 5.5 0.00014 21.9 5.5 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFH46852.1 - 0.0025 17.6 8.7 0.019 14.8 8.8 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFH46852.1 - 0.057 13.6 3.3 0.046 13.9 1.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 TerY_C PF15616.6 KFH46852.1 - 0.24 11.5 1.0 0.41 10.8 0.2 1.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-MIZ PF02891.20 KFH46852.1 - 0.35 10.6 4.8 1.9 8.3 4.9 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KFH46852.1 - 0.52 10.6 4.5 1.6 9.1 4.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Lar_restr_allev PF14354.6 KFH46852.1 - 1.6 9.2 3.4 3.1 8.3 1.0 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 KFH46852.1 - 4 7.0 4.9 5 6.7 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HAD_2 PF13419.6 KFH46853.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH46853.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like CH PF00307.31 KFH46854.1 - 2.3e-67 224.0 0.0 3.7e-17 62.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFH46854.1 - 9.5e-06 26.0 0.4 0.00011 22.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFH46854.1 - 0.017 14.7 0.8 5.2 6.8 0.1 3.6 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KFH46854.1 - 0.024 14.5 0.8 1 9.4 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain CAMSAP_CH PF11971.8 KFH46854.1 - 0.14 12.0 0.0 12 5.8 0.0 3.1 3 0 0 3 3 3 0 CAMSAP CH domain RRM_1 PF00076.22 KFH46857.1 - 2.5e-05 24.0 0.1 7.3e-05 22.5 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L22 PF00237.19 KFH46858.1 - 3.4e-20 72.2 0.2 1.4e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF2722 PF10846.8 KFH46859.1 - 0.018 14.0 8.2 0.021 13.8 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SRAP PF02586.14 KFH46860.1 - 7.8e-82 274.1 0.0 9.9e-82 273.7 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Fungal_trans PF04082.18 KFH46861.1 - 5.9e-28 97.6 0.5 9.1e-28 97.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46861.1 - 1.9e-08 34.3 11.1 3.3e-08 33.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.29 KFH46862.1 - 4.6e-17 62.4 0.0 2.6e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.18 KFH46863.1 - 2.4e-13 49.7 0.1 3.6e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.22 KFH46864.1 - 8.6e-53 176.1 0.1 3.4e-19 68.4 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH46864.1 - 7.9e-38 128.2 0.0 8e-27 92.9 0.0 3.7 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFH46864.1 - 4.7e-11 42.5 0.0 0.025 14.6 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFH46864.1 - 1e-09 38.0 0.0 6.2e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFH46864.1 - 0.00042 20.2 0.0 0.55 10.2 0.0 3.4 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFH46864.1 - 0.0052 16.8 0.1 1.5 9.0 0.0 3.2 2 0 0 2 2 2 1 RNA binding motif BRAP2 PF07576.12 KFH46864.1 - 0.011 15.9 0.1 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFH46864.1 - 0.094 12.8 0.0 9.2 6.5 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif TPR_14 PF13428.6 KFH46864.1 - 2.1 9.4 7.8 41 5.4 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DDHD PF02862.17 KFH46865.1 - 1.8e-64 218.0 0.0 1.2e-63 215.3 0.0 2.3 2 0 0 2 2 2 1 DDHD domain AAR2 PF05282.11 KFH46865.1 - 0.1 12.0 0.6 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 AAR2 protein adh_short_C2 PF13561.6 KFH46866.1 - 4.5e-52 176.9 0.0 5.9e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH46866.1 - 2.9e-39 134.6 0.0 3.8e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH46866.1 - 1.3e-08 35.0 0.3 1.8e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFH46866.1 - 0.031 13.6 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CTP_transf_like PF01467.26 KFH46867.1 - 1.6e-32 112.7 0.0 3e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 KFH46867.1 - 0.055 13.6 0.2 0.73 10.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5639) Pex14_N PF04695.13 KFH46867.1 - 0.4 11.3 2.8 0.31 11.7 0.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 KFH46868.1 - 2.1e-47 161.8 39.3 2.1e-47 161.8 39.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH46868.1 - 2.8e-19 69.3 33.9 4.8e-18 65.3 7.1 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KFH46868.1 - 2.6e-05 22.9 14.2 2.6e-05 22.9 14.2 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SAYSvFN PF10260.9 KFH46868.1 - 0.39 10.7 2.6 3.3 7.7 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) CHAP PF05257.16 KFH46869.1 - 1.8e-14 54.0 4.0 4.2e-14 52.9 4.0 1.6 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.11 KFH46869.1 - 9.3e-07 29.0 0.2 3.5e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 KFH46869.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain Abhydrolase_3 PF07859.13 KFH46870.1 - 0.15 11.9 0.4 0.3 10.9 0.2 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 KFH46871.1 - 8.1e-32 110.8 0.0 1.5e-31 110.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFH46871.1 - 2.4e-06 27.0 0.4 0.00073 18.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH46871.1 - 7.6e-06 25.4 0.1 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFH46871.1 - 4.4e-05 23.0 0.7 0.05 12.9 0.1 2.5 2 1 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KFH46871.1 - 9.6e-05 22.1 1.2 0.0035 17.0 0.6 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH46871.1 - 0.00018 21.0 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH46871.1 - 0.00036 20.7 0.1 0.001 19.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KFH46871.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KFH46871.1 - 0.0022 18.5 0.2 0.033 14.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH46871.1 - 0.0044 16.1 1.0 0.92 8.5 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KFH46871.1 - 0.014 14.1 0.2 0.17 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KFH46871.1 - 0.026 13.8 0.1 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KFH46871.1 - 0.034 13.2 0.6 0.034 13.2 0.6 2.1 2 1 0 3 3 3 0 FAD binding domain SE PF08491.10 KFH46871.1 - 0.12 11.4 0.0 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_7 PF13241.6 KFH46871.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UQ_con PF00179.26 KFH46872.1 - 3.3e-32 111.0 0.0 4.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFH46872.1 - 0.045 14.0 0.5 0.071 13.4 0.5 1.7 1 1 0 1 1 1 0 RWD domain RXT2_N PF08595.11 KFH46872.1 - 0.4 10.7 3.2 0.68 9.9 3.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TALPID3 PF15324.6 KFH46872.1 - 0.99 7.0 3.0 1.3 6.7 3.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target YL1 PF05764.13 KFH46872.1 - 2.8 8.0 14.3 4 7.5 14.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CLPTM1 PF05602.12 KFH46873.1 - 1.9e-149 498.3 0.0 2.5e-149 498.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) NMT1 PF09084.11 KFH46874.1 - 7.5e-05 22.8 0.0 0.00025 21.1 0.0 1.9 1 1 1 2 2 2 2 NMT1/THI5 like SBP_bac_3 PF00497.20 KFH46874.1 - 9.8e-05 21.9 0.0 0.00034 20.1 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ADH_zinc_N PF00107.26 KFH46875.1 - 1.2e-08 35.0 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH46875.1 - 0.00022 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH46875.1 - 0.037 15.1 0.0 0.084 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Phage_lysozyme PF00959.19 KFH46876.1 - 3.9e-15 56.2 0.0 5.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Carboxyl_trans PF01039.22 KFH46877.1 - 1.5e-136 455.9 0.0 2.2e-136 455.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain UreF PF01730.16 KFH46879.1 - 2.8e-23 82.9 0.4 2.8e-23 82.9 0.4 1.5 2 0 0 2 2 2 1 UreF Sugarporin_N PF11471.8 KFH46879.1 - 0.007 16.3 3.2 0.025 14.5 3.2 1.9 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF429 PF04250.13 KFH46879.1 - 0.14 11.9 1.4 0.47 10.2 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF429) DnaJ_C PF01556.18 KFH46880.1 - 2.1e-38 131.7 1.2 2.8e-38 131.3 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFH46880.1 - 4.8e-27 93.9 2.9 8.3e-27 93.1 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain Heme_oxygenase PF01126.20 KFH46881.1 - 7.5e-07 29.1 0.0 5.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Heme oxygenase PAP2_3 PF14378.6 KFH46883.1 - 2e-34 118.9 17.4 1.5e-27 96.6 2.7 2.8 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 KFH46883.1 - 3 7.6 13.6 0.039 13.7 2.3 2.9 3 2 0 3 3 3 0 PAP2 superfamily Fungal_trans_2 PF11951.8 KFH46884.1 - 5.7e-48 163.6 0.1 1.4e-47 162.4 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH46884.1 - 1.8e-06 27.9 7.1 3.9e-06 26.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF_4EBP PF05456.11 KFH46884.1 - 8.4 6.4 8.6 3.1 7.8 2.2 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Glyco_hydro_31 PF01055.26 KFH46885.1 - 1.2e-243 809.1 10.2 6.4e-137 457.3 5.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 FLILHELTA PF10306.9 KFH46885.1 - 5.5e-32 110.0 0.1 1.2e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Gal_mutarotas_2 PF13802.6 KFH46885.1 - 9.2e-31 106.0 5.5 4e-25 87.9 0.3 4.5 4 1 0 4 4 4 2 Galactose mutarotase-like Glyco_hydro_18 PF00704.28 KFH46885.1 - 2.5e-14 53.7 0.0 5.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5110 PF17137.4 KFH46885.1 - 2.6e-07 30.8 0.6 9.6e-07 29.0 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF1279 PF06916.13 KFH46885.1 - 0.044 14.3 0.0 0.093 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF4968 PF16338.5 KFH46885.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Acyl-CoA_dh_1 PF00441.24 KFH46886.1 - 1.5e-29 103.2 0.5 2.7e-29 102.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH46886.1 - 1.9e-20 72.8 0.0 3.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFH46886.1 - 3.2e-15 56.8 0.2 1.5e-14 54.6 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH46886.1 - 1.1e-11 45.2 1.3 2.2e-11 44.2 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.11 KFH46888.1 - 6.6e-30 104.4 0.0 1e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAM184 PF15665.5 KFH46889.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FUSC PF04632.12 KFH46889.1 - 0.077 11.5 0.5 0.11 11.0 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DAO PF01266.24 KFH46890.1 - 9.4e-68 229.4 0.7 1.1e-67 229.1 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH46890.1 - 0.0004 20.5 0.1 0.0009 19.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH46890.1 - 0.0016 19.0 0.1 3.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFH46890.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KFH46890.1 - 0.05 12.8 0.6 3.2 6.9 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.13 KFH46891.1 - 4.1e-58 196.4 7.6 4.1e-58 196.4 7.6 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF2721 PF11026.8 KFH46891.1 - 5.5 6.9 17.1 5.9 6.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3188 PF11384.8 KFH46891.1 - 5.8 6.7 6.4 1.9 8.3 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) MMR_HSR1_Xtn PF16897.5 KFH46892.1 - 3.4e-35 120.3 1.1 2.9e-34 117.3 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KFH46892.1 - 1.6e-20 73.3 0.0 3.9e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFH46892.1 - 3.2e-20 71.9 0.1 6.7e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KFH46892.1 - 1.8e-12 47.1 0.0 2.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFH46892.1 - 0.00028 21.0 0.4 0.059 13.4 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KFH46892.1 - 0.076 12.0 0.1 0.18 10.8 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1283 PF06932.11 KFH46893.1 - 0.18 12.1 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) MARVEL PF01284.23 KFH46894.1 - 0.00017 21.7 11.3 0.00025 21.1 11.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain SCAMP PF04144.13 KFH46894.1 - 0.11 12.8 9.8 0.16 12.3 9.8 1.1 1 0 0 1 1 1 0 SCAMP family DUF4281 PF14108.6 KFH46894.1 - 0.28 11.6 3.6 0.096 13.1 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) DUF2070 PF09843.9 KFH46894.1 - 3.4 5.9 5.5 4.5 5.4 5.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PUL PF08324.11 KFH46895.1 - 2.1e-60 204.3 0.4 2.9e-60 203.9 0.4 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KFH46895.1 - 3.7e-34 117.8 0.0 6.3e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KFH46895.1 - 1.7e-14 53.6 0.0 3.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFH46895.1 - 6.2e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KFH46895.1 - 1.4e-05 25.5 0.0 6e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFH46895.1 - 4.7e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFH46895.1 - 0.00047 20.1 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family T4_deiodinase PF00837.17 KFH46895.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_4 PF13462.6 KFH46895.1 - 0.026 14.7 0.1 0.11 12.7 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin DUF2847 PF11009.8 KFH46895.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) PAD_N PF08526.10 KFH46895.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain Thioredoxin_8 PF13905.6 KFH46895.1 - 0.093 13.1 0.0 0.58 10.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Redoxin PF08534.10 KFH46895.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Redoxin AAA_lid_2 PF17863.1 KFH46897.1 - 6.8e-09 35.4 0.6 1.5e-08 34.4 0.6 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KFH46897.1 - 0.036 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PHD PF00628.29 KFH46898.1 - 4.7e-09 36.0 1.4 1.2e-08 34.7 1.4 1.7 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KFH46898.1 - 0.0035 17.2 2.6 0.017 15.0 2.6 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.6 KFH46898.1 - 0.0099 15.4 1.8 0.016 14.7 1.8 1.4 1 0 0 1 1 1 1 PHD-finger CEBP_ZZ PF16366.5 KFH46898.1 - 0.12 12.7 2.1 0.31 11.3 2.1 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PhoLip_ATPase_C PF16212.5 KFH46899.1 - 1.9e-50 172.0 5.8 1.9e-50 172.0 5.8 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFH46899.1 - 1.9e-16 59.5 0.5 3.9e-16 58.5 0.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFH46899.1 - 1.5e-13 51.5 0.0 4.5e-07 30.4 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFH46899.1 - 2.4e-08 33.7 0.5 0.0009 18.8 0.1 3.0 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KFH46899.1 - 8.4e-05 22.6 0.0 0.0025 17.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFH46899.1 - 0.0024 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TrmE_N PF10396.9 KFH46900.1 - 2.9e-36 124.3 0.0 5.8e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KFH46900.1 - 1.5e-35 123.2 2.4 2e-35 122.9 2.4 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KFH46900.1 - 5.3e-18 65.2 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFH46900.1 - 4.5e-05 23.0 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFH46900.1 - 0.0016 18.5 0.0 0.0052 16.9 0.0 2.0 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KFH46900.1 - 0.0061 16.5 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KFH46900.1 - 0.033 13.9 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain BORCS7 PF16088.5 KFH46900.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 ABC_tran PF00005.27 KFH46900.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter CorA PF01544.18 KFH46900.1 - 0.69 9.2 1.7 1.1 8.6 1.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3425 PF11905.8 KFH46901.1 - 8.1e-23 80.7 0.0 1.5e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DLH PF01738.18 KFH46903.1 - 7.7e-21 74.6 0.0 8.8e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Glyco_hydro_63 PF03200.16 KFH46904.1 - 8.6e-174 578.9 2.2 1.3e-172 575.0 2.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KFH46904.1 - 3e-75 253.2 0.1 2.1e-74 250.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KFH46904.1 - 9.8e-09 34.6 0.1 1.8e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Trehalase DUF3093 PF11292.8 KFH46904.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Vps55 PF04133.14 KFH46905.1 - 2.3e-45 153.3 9.2 2.6e-45 153.1 9.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 KFH46905.1 - 0.5 9.8 0.0 0.5 9.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Proteasome PF00227.26 KFH46907.1 - 5e-43 146.8 0.2 6.7e-43 146.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFH46907.1 - 5e-11 42.1 0.2 7.8e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature adh_short PF00106.25 KFH46908.1 - 6e-20 71.5 0.0 9.8e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH46908.1 - 7e-16 58.5 0.0 1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFH46908.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 KFH46908.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 KR domain WD40 PF00400.32 KFH46909.1 - 3e-13 50.0 8.1 0.015 16.2 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH46909.1 - 4.9e-05 23.5 0.1 24 5.3 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2264 PF10022.9 KFH46910.1 - 1.1e-133 445.7 0.4 1.4e-133 445.3 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Peptidase_S58 PF03576.14 KFH46911.1 - 2.8e-81 273.3 0.2 3.2e-81 273.1 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 Elong_Iki1 PF10483.9 KFH46913.1 - 8e-103 344.0 0.0 9.2e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NDK PF00334.19 KFH46914.1 - 2.1e-54 183.2 0.0 2.6e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HAD_2 PF13419.6 KFH46915.1 - 1.7e-22 80.4 0.0 2.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH46915.1 - 4.8e-08 33.5 0.1 2e-07 31.5 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH46915.1 - 9.6e-06 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KFH46915.1 - 1.1e-05 25.2 0.0 0.0041 16.9 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase CTP_synth_N PF06418.14 KFH46916.1 - 3.4e-105 351.1 0.1 6.7e-105 350.2 0.1 1.5 1 1 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFH46916.1 - 7e-51 172.7 0.0 1.2e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFH46916.1 - 0.02 14.6 0.1 0.071 12.9 0.1 1.9 1 1 0 1 1 1 0 Peptidase C26 ArsA_ATPase PF02374.15 KFH46916.1 - 0.03 13.5 0.2 0.061 12.5 0.2 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.23 KFH46916.1 - 0.15 12.1 0.1 0.32 11.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FH2 PF02181.23 KFH46917.1 - 2.1e-84 283.8 5.4 2.1e-84 283.8 5.4 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KFH46917.1 - 3.4e-59 199.6 0.0 9.5e-59 198.1 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KFH46917.1 - 3.5e-51 173.6 1.6 4.3e-50 170.1 1.6 2.6 1 1 0 1 1 1 1 Diaphanous FH3 Domain Aminotran_5 PF00266.19 KFH46918.1 - 3.6e-34 118.3 0.0 2.8e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Mso1_Sec1_bdg PF14475.6 KFH46919.1 - 2.2e-21 75.1 0.1 3.7e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 SUIM_assoc PF16619.5 KFH46919.1 - 0.02 15.0 0.8 0.02 15.0 0.8 2.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 GFO_IDH_MocA PF01408.22 KFH46920.1 - 2.9e-09 37.8 0.0 6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AA_permease PF00324.21 KFH46921.1 - 5.3e-57 193.5 24.5 6.8e-57 193.1 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFH46921.1 - 1.3e-21 77.1 10.3 6.5e-10 38.6 0.0 3.6 4 0 0 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 KFH46921.1 - 6.5e-17 61.5 29.6 9.5e-17 60.9 29.6 1.2 1 0 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 KFH46922.1 - 6.1e-28 97.2 0.0 3e-10 40.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH46922.1 - 3.7e-26 91.2 0.4 1.1e-07 32.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFH46922.1 - 5e-21 74.2 1.1 2.3e-07 30.9 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KFH46922.1 - 1.7e-17 63.2 0.6 1.4e-08 34.8 0.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH46922.1 - 3.4e-17 60.7 0.1 0.00038 20.7 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat HGTP_anticodon2 PF12745.7 KFH46923.1 - 1.4e-78 264.1 3.1 1.4e-78 264.1 3.1 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KFH46923.1 - 1.6e-73 247.3 0.2 3.7e-35 121.6 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46923.1 - 1.7e-45 155.3 0.0 2.7e-21 76.0 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KFH46923.1 - 2.9e-20 72.8 0.0 8.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 KFH46923.1 - 2.3e-12 47.2 0.0 5.9e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KFH46923.1 - 7.3e-09 35.9 1.8 0.0044 17.0 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFH46923.1 - 0.024 14.3 0.4 0.88 9.1 0.0 3.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PEARLI-4 PF05278.12 KFH46923.1 - 0.028 14.0 0.1 0.028 14.0 0.1 2.4 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF1682 PF07946.14 KFH46923.1 - 8.8 5.4 15.9 15 4.7 15.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hus1 PF04005.12 KFH46924.1 - 1.6e-88 296.6 0.0 2e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein MFS_1 PF07690.16 KFH46925.1 - 3.5e-25 88.7 43.7 2.6e-20 72.7 27.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily EptA_B_N PF08019.12 KFH46925.1 - 0.054 13.4 0.7 0.25 11.2 0.7 2.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Acyl-CoA_dh_1 PF00441.24 KFH46926.1 - 1.3e-41 142.3 0.8 3e-41 141.1 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH46926.1 - 8.1e-34 116.7 0.1 1.6e-33 115.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFH46926.1 - 5.8e-27 93.7 0.1 1.1e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFH46926.1 - 1.8e-13 51.0 0.1 4.2e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFH46926.1 - 0.00028 20.6 0.1 0.00067 19.4 0.1 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AhpC-TSA PF00578.21 KFH46926.1 - 0.043 13.7 0.1 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family Glyco_hydro_3_C PF01915.22 KFH46927.1 - 6.9e-39 133.9 0.0 1e-38 133.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH46927.1 - 3.5e-31 108.7 0.0 5.6e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ank_5 PF13857.6 KFH46928.1 - 0.00071 19.8 0.2 0.88 10.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFH46928.1 - 0.0012 19.3 0.0 0.097 13.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH46928.1 - 0.0013 19.2 0.0 0.0066 17.0 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) F-box-like PF12937.7 KFH46928.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like Ank_3 PF13606.6 KFH46928.1 - 0.14 12.8 0.2 19 6.2 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeat Cut12 PF11500.8 KFH46929.1 - 1.8e-44 151.2 16.7 1.8e-44 151.2 16.7 3.7 2 1 0 2 2 2 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.12 KFH46929.1 - 0.0082 16.0 6.8 0.67 9.9 0.8 3.9 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat UBA_4 PF14555.6 KFH46930.1 - 0.0029 17.4 0.2 0.0075 16.1 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 KFH46930.1 - 6.7 6.9 10.7 3.8 7.6 7.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif HET PF06985.11 KFH46932.1 - 1.7e-12 47.9 0.2 4.5e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_Rpb1_6 PF04992.14 KFH46932.1 - 0.12 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 BRCT PF00533.26 KFH46933.1 - 1.2e-06 28.8 0.0 2.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFH46933.1 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KFH46933.1 - 0.0033 17.8 0.0 0.0076 16.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFH46933.1 - 0.087 12.9 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain EamA PF00892.20 KFH46934.1 - 1e-14 54.9 28.9 1.1e-08 35.3 1.1 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 KFH46934.1 - 7.2e-08 32.1 0.7 7.2e-08 32.1 0.7 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KFH46934.1 - 1.8e-07 30.7 0.5 1.8e-07 30.7 0.5 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KFH46934.1 - 3e-05 23.7 8.0 5.6e-05 22.8 8.0 1.5 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 KFH46934.1 - 0.057 12.7 5.7 0.085 12.2 0.3 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 KFH46934.1 - 0.2 10.6 8.0 0.031 13.2 1.2 2.2 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Sugar_tr PF00083.24 KFH46935.1 - 1.9e-85 287.4 26.8 2.4e-85 287.1 26.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46935.1 - 2.1e-15 56.5 33.8 5.5e-15 55.2 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spo12 PF05032.12 KFH46937.1 - 5.5e-16 58.2 0.9 5.5e-16 58.2 0.9 1.8 2 0 0 2 2 2 1 Spo12 family GSHPx PF00255.19 KFH46938.1 - 3e-43 145.8 0.1 3.8e-43 145.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 KFH46938.1 - 0.0019 17.9 0.0 0.0023 17.6 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFH46938.1 - 0.0087 16.0 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF997 PF06196.12 KFH46939.1 - 0.14 12.2 0.6 0.25 11.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EGF_2 PF07974.13 KFH46939.1 - 2.9 8.3 11.7 5.7 7.4 11.7 1.5 1 0 0 1 1 1 0 EGF-like domain Torus PF16131.5 KFH46940.1 - 1e-41 142.0 0.3 1e-41 142.0 0.3 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KFH46940.1 - 3.3e-08 33.2 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH46940.1 - 0.0023 17.9 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KFH46940.1 - 0.0034 17.4 2.4 0.0034 17.4 2.4 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-C2H2_assoc PF16606.5 KFH46940.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers MMR_HSR1 PF01926.23 KFH46941.1 - 5.5e-14 52.2 0.0 1.3e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH46941.1 - 8.8e-07 29.0 0.1 2.1e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFH46941.1 - 0.00082 18.9 0.3 0.0019 17.8 0.3 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFH46941.1 - 0.0011 19.0 0.1 0.69 9.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 KFH46941.1 - 0.0023 18.3 0.1 0.005 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 KFH46941.1 - 0.0056 16.0 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KFH46941.1 - 0.027 15.0 0.1 0.071 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFH46941.1 - 0.089 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KFH46941.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.27 KFH46941.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Nop16 PF09420.10 KFH46942.1 - 1.6e-68 230.9 10.3 1.8e-68 230.7 10.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 GDA1_CD39 PF01150.17 KFH46943.1 - 7.1e-102 341.2 0.0 9e-102 340.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Lysine_decarbox PF03641.14 KFH46944.1 - 3.9e-29 101.4 0.0 5.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KFH46944.1 - 3.8e-05 23.3 0.5 0.00019 21.0 0.1 2.0 2 0 0 2 2 2 1 SLOG cluster4 family LSDAT_prok PF18171.1 KFH46944.1 - 0.057 12.7 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Ras PF00071.22 KFH46945.1 - 9e-57 191.2 0.0 1.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH46945.1 - 1.3e-32 112.5 0.0 1.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH46945.1 - 1.3e-14 54.0 0.0 1.5e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH46945.1 - 2.4e-08 34.0 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFH46945.1 - 7.9e-07 28.7 0.0 9.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFH46945.1 - 5e-06 26.2 0.0 0.00015 21.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFH46945.1 - 0.0002 21.3 0.2 0.0037 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KFH46945.1 - 0.002 17.9 0.1 0.065 13.0 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KFH46945.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KFH46945.1 - 0.005 16.6 0.2 0.16 11.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFH46945.1 - 0.0072 16.6 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KFH46945.1 - 0.0087 15.4 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Septin cobW PF02492.19 KFH46945.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFH46945.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH46945.1 - 0.018 15.4 0.0 0.032 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFH46945.1 - 0.033 13.7 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFH46945.1 - 0.056 13.3 0.1 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KFH46945.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFH46945.1 - 0.1 13.0 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 KFH46945.1 - 0.11 12.0 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KFH46945.1 - 0.11 11.6 0.3 0.24 10.5 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 KFH46945.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 KFH46945.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 KFH46945.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 KFH46945.1 - 0.22 10.7 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 KFH46945.1 - 0.23 10.6 1.6 0.7 9.0 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_21 PF13304.6 KFH46945.1 - 0.49 10.1 2.5 2.2 8.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FAD_binding_6 PF00970.24 KFH46946.1 - 2.5e-06 27.8 0.0 2.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFH46946.1 - 0.00022 21.8 0.0 0.00091 19.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFH46946.1 - 0.042 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Glyco_hydro_18 PF00704.28 KFH46947.1 - 1.9e-20 73.9 0.8 1.2e-18 67.9 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LsmAD PF06741.13 KFH46948.1 - 0.35 11.4 3.3 2 9.0 0.4 2.5 2 0 0 2 2 2 0 LsmAD domain Ribosomal_L28e PF01778.17 KFH46949.1 - 3.6e-39 134.1 2.0 9.1e-39 132.8 2.0 1.7 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KFH46949.1 - 7.3e-27 93.9 18.2 7.3e-27 93.9 18.2 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KFH46949.1 - 4.6e-08 32.8 14.5 5.9e-08 32.5 14.5 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KFH46949.1 - 0.0019 18.0 1.5 0.0032 17.2 1.5 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CRA PF06589.11 KFH46949.1 - 0.0055 16.8 2.1 0.0055 16.8 2.1 2.4 2 0 0 2 2 2 1 Circumsporozoite-related antigen (CRA) TFIIA PF03153.13 KFH46949.1 - 0.014 15.4 9.2 0.018 15.1 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.12 KFH46949.1 - 0.11 11.1 25.4 0.14 10.7 25.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LTV PF04180.14 KFH46949.1 - 0.27 10.9 18.7 0.37 10.5 18.7 1.2 1 0 0 1 1 1 0 Low temperature viability protein SURF2 PF05477.11 KFH46949.1 - 0.82 9.3 13.3 1.4 8.5 13.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 KFH46949.1 - 3.3 5.8 28.7 4.4 5.4 28.7 1.1 1 0 0 1 1 1 0 Nop14-like family PetN PF03742.14 KFH46950.1 - 0.58 10.1 0.0 0.58 10.1 0.0 2.2 3 0 0 3 3 3 0 PetN Zn_clus PF00172.18 KFH46951.1 - 0.0025 17.9 15.6 0.0025 17.9 15.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAPPC9-Trs120 PF08626.11 KFH46952.1 - 0 1407.7 0.0 0 1407.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 KFH46952.1 - 0.11 12.7 0.9 0.99 9.7 0.1 2.6 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Nucleoporin_FG PF13634.6 KFH46953.1 - 0.2 12.5 2.0 0.53 11.2 2.0 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region HCO3_cotransp PF00955.21 KFH46954.1 - 9.3e-66 222.7 6.8 7.8e-36 124.0 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Carb_anhydrase PF00194.21 KFH46955.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Sugar_tr PF00083.24 KFH46956.1 - 1.6e-120 403.0 26.6 1.9e-120 402.8 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH46956.1 - 6.7e-25 87.8 24.1 6.7e-25 87.8 24.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily COPIIcoated_ERV PF07970.12 KFH46957.1 - 3e-40 138.4 0.0 4.8e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFH46957.1 - 4.7e-21 75.0 0.0 8e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ASXH PF13919.6 KFH46958.1 - 1.7e-39 135.0 0.3 2.8e-39 134.3 0.3 1.4 1 0 0 1 1 1 1 Asx homology domain XRCC4 PF06632.12 KFH46958.1 - 0.093 11.6 1.1 0.17 10.7 1.1 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SRP-alpha_N PF04086.13 KFH46958.1 - 4.6 7.1 9.0 0.39 10.6 1.1 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal GATase_4 PF13230.6 KFH46959.1 - 3.9e-16 58.8 0.1 6.4e-14 51.5 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KFH46959.1 - 2e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Sec16_C PF12931.7 KFH46960.1 - 2.4e-110 369.0 0.0 3.3e-110 368.5 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFH46960.1 - 6.7e-33 113.8 0.0 1.7e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KFH46960.1 - 1.6e-10 41.6 24.0 1.6e-10 41.6 24.0 4.6 3 1 0 3 3 3 2 Vesicle coat trafficking protein Sec16 N-terminus Longin PF13774.6 KFH46961.1 - 5.9e-25 87.1 0.1 8.7e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFH46961.1 - 5.2e-15 55.0 0.0 4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 KFH46961.1 - 0.045 13.5 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Sirohm_synth_C PF14823.6 KFH46961.1 - 2.2 8.0 4.0 12 5.6 0.4 2.5 2 1 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal CAF1A PF12253.8 KFH46962.1 - 2e-21 75.9 3.7 2e-21 75.9 3.7 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KFH46962.1 - 0.0086 15.8 41.4 0.025 14.3 41.4 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF966 PF06136.13 KFH46962.1 - 0.28 10.9 25.4 0.45 10.2 25.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.9 KFH46962.1 - 3.2 6.2 20.8 4.4 5.8 20.8 1.1 1 0 0 1 1 1 0 Macoilin family Oxidored_FMN PF00724.20 KFH46963.1 - 3.4e-80 269.9 0.0 4.8e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 KFH46963.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Nucleo_P87 PF07267.11 KFH46964.1 - 0.26 10.1 0.1 0.33 9.8 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 cobW PF02492.19 KFH46965.1 - 1.1e-40 139.0 0.0 3e-40 137.7 0.0 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KFH46965.1 - 0.00012 22.0 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KFH46965.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFH46965.1 - 0.024 14.9 0.0 0.094 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KFH46965.1 - 0.035 13.0 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.6 KFH46965.1 - 0.039 13.7 0.3 0.39 10.5 0.1 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH46965.1 - 0.048 13.6 0.0 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase CobW_C PF07683.14 KFH46965.1 - 0.056 13.4 0.0 0.36 10.8 0.0 2.4 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain NTPase_1 PF03266.15 KFH46965.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KFH46965.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFH46965.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 KFH46965.1 - 0.13 11.2 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Thioredoxin PF00085.20 KFH46966.1 - 1.4e-24 86.1 0.0 1.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFH46966.1 - 2.3e-07 31.0 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFH46966.1 - 6.8e-07 29.7 0.3 1.4e-06 28.7 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFH46966.1 - 8e-07 28.7 0.0 8.1e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFH46966.1 - 2.8e-05 24.0 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KFH46966.1 - 0.00023 21.3 0.1 0.00034 20.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFH46966.1 - 0.0018 18.0 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFH46966.1 - 0.0026 17.6 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KFH46966.1 - 0.0068 16.1 0.2 0.032 14.0 0.2 1.7 1 1 1 2 2 2 1 Redoxin HyaE PF07449.11 KFH46966.1 - 0.066 13.2 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KFH46966.1 - 0.087 12.9 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin domain Phosducin PF02114.16 KFH46966.1 - 0.099 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin MS_channel PF00924.18 KFH46967.1 - 1.8e-19 70.1 0.9 3.5e-19 69.2 0.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KFH46967.1 - 0.0029 17.0 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KFH46967.1 - 0.0042 16.5 0.2 0.01 15.3 0.2 1.7 1 0 0 1 1 1 1 EF hand WXG100 PF06013.12 KFH46967.1 - 0.0053 17.0 0.8 0.26 11.5 0.1 2.7 2 0 0 2 2 2 1 Proteins of 100 residues with WXG EF-hand_7 PF13499.6 KFH46967.1 - 0.0066 16.9 0.9 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFH46967.1 - 0.024 14.6 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KFH46967.1 - 0.051 13.4 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair OmdA PF13376.6 KFH46967.1 - 0.27 11.3 4.2 1.2 9.2 0.7 2.5 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Rit1_C PF17184.4 KFH46968.1 - 3.5e-103 344.8 0.0 4.4e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KFH46968.1 - 6.1e-32 110.2 0.0 1.1e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Aa_trans PF01490.18 KFH46969.1 - 8.4e-84 281.6 30.4 1e-83 281.4 30.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Suc_Fer-like PF06999.12 KFH46969.1 - 4.2e-57 193.2 0.0 5.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hydro_76 PF03663.14 KFH46970.1 - 8.4e-147 489.5 7.4 9.8e-147 489.2 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RabGAP-TBC PF00566.18 KFH46971.1 - 9.9e-38 129.9 3.8 2.1e-37 128.9 3.8 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFH46971.1 - 2.9e-06 26.9 0.0 0.028 13.9 0.0 2.9 3 0 0 3 3 3 2 Rab-binding domain (RBD) DHDPS PF00701.22 KFH46972.1 - 1.7e-32 112.3 0.0 2.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SNRNP27 PF08648.12 KFH46973.1 - 7.4e-29 99.6 0.3 1.2e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins NAC PF01849.18 KFH46974.1 - 6.9e-24 83.6 0.4 1.9e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 NAC domain Cwf_Cwc_15 PF04889.12 KFH46974.1 - 0.69 9.6 12.9 4.8 6.8 6.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 KFH46975.1 - 4.8e-50 170.4 0.0 6.7e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH46975.1 - 2e-25 89.6 0.5 1.4e-24 86.8 0.5 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH46975.1 - 0.0014 17.5 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFH46975.1 - 0.0089 15.7 1.2 0.47 10.0 0.1 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFH46975.1 - 0.12 11.6 0.5 0.33 10.2 0.1 1.9 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 KFH46975.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KFH46976.1 - 5.8e-19 68.2 0.4 7.2e-19 67.9 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Autophagy_N PF03986.13 KFH46977.1 - 6.8e-47 158.9 0.6 1.1e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KFH46977.1 - 5.5e-16 57.8 0.6 1e-15 56.9 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KFH46977.1 - 4e-15 56.1 0.1 7.2e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Pro_isomerase PF00160.21 KFH46978.1 - 2e-52 177.6 0.0 2.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AdoMet_MTase PF07757.13 KFH46979.1 - 2.7e-39 133.9 0.0 4.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KFH46979.1 - 0.005 16.9 0.0 0.038 14.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH46979.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mcp5_PH PF12814.7 KFH46980.1 - 3.5e-46 156.3 0.1 6.5e-46 155.4 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KFH46980.1 - 1.3e-05 25.6 0.0 3.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PH domain RasGAP_C PF03836.15 KFH46980.1 - 0.52 10.4 17.5 0.03 14.5 10.6 2.2 2 0 0 2 2 2 0 RasGAP C-terminus CFEM PF05730.11 KFH46981.1 - 6.5e-09 35.8 10.0 8.4e-09 35.4 10.0 1.1 1 0 0 1 1 1 1 CFEM domain Methyltransf_16 PF10294.9 KFH46982.1 - 8.1e-16 58.2 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KFH46982.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH46982.1 - 2.8e-05 24.7 0.0 6.6e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH46982.1 - 0.00012 22.8 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFH46982.1 - 0.00095 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFH46982.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFH46982.1 - 0.021 15.4 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KFH46982.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 KFH46982.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFH46982.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Abhydrolase_1 PF00561.20 KFH46983.1 - 2.1e-12 47.2 0.1 2.8e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH46983.1 - 2.7e-12 47.8 5.3 3.6e-12 47.4 5.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH46983.1 - 3.3e-12 46.2 0.4 6.8e-12 45.2 0.4 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KFH46983.1 - 4.2e-07 29.7 0.7 0.00024 20.7 0.1 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFH46983.1 - 7.5e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 KFH46983.1 - 0.00019 21.2 0.3 0.0058 16.3 0.3 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 KFH46983.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.8 1 1 0 2 2 2 1 Thioesterase domain DUF2048 PF09752.9 KFH46983.1 - 0.00072 18.7 0.0 0.00094 18.4 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Peptidase_S9 PF00326.21 KFH46983.1 - 0.00085 18.9 1.2 0.013 15.0 0.2 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFH46983.1 - 0.0011 19.0 0.1 0.0072 16.3 0.1 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KFH46983.1 - 0.0054 16.5 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KFH46983.1 - 0.014 15.2 0.5 0.063 13.1 0.5 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold PhoPQ_related PF10142.9 KFH46983.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.20 KFH46983.1 - 0.061 13.0 0.1 0.091 12.4 0.1 1.5 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 KFH46983.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.32 KFH46985.1 - 6.9e-22 77.3 13.5 6.2e-06 26.8 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KFH46985.1 - 4.6e-05 22.1 1.8 0.0015 17.2 0.0 3.3 3 1 0 4 4 4 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KFH46985.1 - 6.7e-05 23.1 0.0 0.018 15.3 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFH46985.1 - 0.082 12.2 0.0 3 7.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain BUD22 PF09073.10 KFH46985.1 - 5.4 6.2 7.4 7.9 5.7 7.4 1.2 1 0 0 1 1 1 0 BUD22 PD40 PF07676.12 KFH46985.1 - 5.6 7.0 7.3 0.25 11.3 0.2 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HeLo PF14479.6 KFH46988.1 - 3.2e-12 46.7 3.4 2.5e-10 40.6 0.5 2.4 1 1 1 2 2 2 2 Prion-inhibition and propagation NACHT PF05729.12 KFH46988.1 - 8.5e-09 35.5 0.1 2.4e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFH46988.1 - 6e-05 23.5 0.1 0.00036 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFH46988.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KFH46988.1 - 0.0016 17.7 0.0 0.0058 15.8 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain ATPase PF06745.13 KFH46988.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KFH46988.1 - 0.0074 16.7 0.0 0.035 14.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFH46988.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 KFH46988.1 - 0.018 14.8 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Soyouz_module PF14313.6 KFH46988.1 - 0.026 14.3 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) AAA_19 PF13245.6 KFH46988.1 - 0.028 14.8 0.6 0.52 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KFH46988.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFH46988.1 - 0.11 12.5 0.0 0.4 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 KFH46989.1 - 1.1e-41 143.2 0.0 1.4e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KFH46989.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III MAT1-1-2 PF17043.5 KFH46990.1 - 2.3e-29 102.3 0.0 3.4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function DUF3574 PF12098.8 KFH46990.1 - 0.16 11.8 0.1 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) DHHC PF01529.20 KFH46991.1 - 1.4e-08 34.9 22.8 4.7e-07 30.0 14.0 3.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase ISK_Channel PF02060.15 KFH46991.1 - 0.33 10.7 2.1 0.28 10.9 0.4 1.7 2 0 0 2 2 2 0 Slow voltage-gated potassium channel PHO4 PF01384.20 KFH46991.1 - 1 8.4 2.2 4.1 6.4 0.2 1.9 1 1 0 2 2 2 0 Phosphate transporter family Peptidase_A22B PF04258.13 KFH46992.1 - 3e-53 181.2 3.2 1.4e-33 116.6 0.3 2.2 2 0 0 2 2 2 2 Signal peptide peptidase Ribosomal_60s PF00428.19 KFH46992.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM176 PF14851.6 KFH46992.1 - 0.17 11.5 3.7 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KFH46992.1 - 2.5 8.5 6.7 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Slu7 PF11708.8 KFH46993.1 - 1e-74 251.7 19.6 1e-74 251.7 19.6 3.4 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFH46993.1 - 0.021 14.6 0.6 0.042 13.6 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2076 PF09849.9 KFH46994.1 - 5.9e-06 26.5 21.5 1.1e-05 25.7 21.6 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KFH46994.1 - 0.00013 22.0 4.1 0.00021 21.4 4.1 1.4 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KFH46994.1 - 0.019 15.3 2.6 0.031 14.7 2.6 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Antimicrobial24 PF16049.5 KFH46994.1 - 0.28 11.2 1.5 0.62 10.1 1.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide MTCP1 PF08991.10 KFH46994.1 - 0.39 11.0 3.2 0.62 10.3 3.2 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Zn_ribbon_17 PF17120.5 KFH46995.1 - 2.3e-06 27.1 10.1 4.3e-06 26.2 10.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KFH46995.1 - 3e-05 24.7 23.8 0.00081 20.1 0.2 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat RWD PF05773.22 KFH46995.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KFH46995.1 - 0.051 13.9 5.5 0.11 12.8 5.5 1.5 1 0 0 1 1 1 0 Ring finger domain DLH PF01738.18 KFH46996.1 - 1.4e-15 57.4 0.1 1.7e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Ribosomal_L21e PF01157.18 KFH46997.1 - 1e-45 153.7 4.4 1e-45 153.7 4.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e NaeI PF09126.10 KFH46997.1 - 0.084 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease NaeI SH3_13 PF18335.1 KFH46997.1 - 0.096 12.5 0.6 0.096 12.5 0.6 1.7 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain SET PF00856.28 KFH46998.1 - 1.5e-07 31.9 0.0 2.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Cupin_2 PF07883.11 KFH46999.1 - 0.048 13.4 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Cupin domain HATPase_c PF02518.26 KFH47000.1 - 5.9e-21 75.1 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH47000.1 - 3.5e-17 62.6 0.0 6.7e-12 45.6 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.7 KFH47000.1 - 6.5e-13 48.8 0.0 3.2e-05 24.1 0.0 3.7 3 1 0 3 3 3 2 PAS domain PAS_3 PF08447.12 KFH47000.1 - 9.4e-12 45.1 0.0 0.00023 21.4 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KFH47000.1 - 2.7e-11 43.2 0.0 3.7e-06 26.8 0.0 3.7 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 KFH47000.1 - 2.9e-07 30.4 1.7 2.1e-06 27.7 0.2 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KFH47000.1 - 5.1e-06 26.5 0.0 0.027 14.5 0.0 4.0 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 KFH47000.1 - 0.00056 20.1 0.0 14 6.0 0.0 4.6 4 0 0 4 4 4 1 PAS fold SecE PF00584.20 KFH47001.1 - 9e-12 44.7 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coq4 PF05019.13 KFH47002.1 - 1.6e-96 321.9 0.0 1.9e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SUI1 PF01253.22 KFH47003.1 - 5.1e-28 97.4 4.2 7.1e-28 97.0 4.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mid2 PF04478.12 KFH47004.1 - 6.6e-07 29.3 1.0 1.2e-06 28.4 0.0 2.0 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor PRCC PF10253.9 KFH47004.1 - 0.00095 20.0 7.8 0.0014 19.5 7.8 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting SKG6 PF08693.10 KFH47004.1 - 0.02 14.3 2.2 0.042 13.3 2.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM51 PF15345.6 KFH47004.1 - 0.032 14.1 1.3 0.12 12.2 0.0 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 Plasmodium_Vir PF05795.11 KFH47004.1 - 0.13 11.6 0.7 0.19 11.1 0.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 KFH47004.1 - 0.18 11.7 9.0 0.21 11.5 9.0 1.2 1 0 0 1 1 1 0 SPX domain TMEM100 PF16311.5 KFH47004.1 - 0.23 11.0 0.0 0.45 10.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Polyketide_cyc2 PF10604.9 KFH47005.1 - 0.044 14.1 0.0 0.2 11.9 0.0 2.0 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport NPP1 PF05630.11 KFH47006.1 - 1.5e-64 217.7 0.1 1.8e-64 217.5 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) G-alpha PF00503.20 KFH47007.1 - 6.9e-35 120.9 0.0 1.3e-34 120.0 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit ATP_bind_1 PF03029.17 KFH47007.1 - 0.00089 19.1 0.1 0.61 9.8 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KFH47007.1 - 0.0025 18.0 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFH47007.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KFH47007.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KFH47007.1 - 0.021 14.8 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFH47007.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFH47007.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFH47007.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFH47007.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KFH47007.1 - 0.068 12.2 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain cobW PF02492.19 KFH47007.1 - 0.098 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 KFH47007.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KFH47007.1 - 0.15 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KFH47007.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFH47007.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Med31 PF05669.12 KFH47008.1 - 3.8e-37 126.2 2.3 4.5e-37 125.9 2.3 1.0 1 0 0 1 1 1 1 SOH1 RRM_1 PF00076.22 KFH47009.1 - 1.1e-19 70.1 0.0 2e-08 33.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP-alpha_N PF04086.13 KFH47010.1 - 1.5e-76 258.1 0.1 2e-76 257.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFH47010.1 - 3.3e-52 177.0 0.1 7.1e-52 175.9 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFH47010.1 - 2e-08 34.4 0.3 6.1e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFH47010.1 - 1.6e-05 24.0 0.0 3.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFH47010.1 - 0.00026 20.8 0.1 0.00056 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFH47010.1 - 0.0024 18.3 0.2 0.0081 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain zf-C2H2_assoc PF16606.5 KFH47010.1 - 0.0024 18.0 2.7 0.0024 18.0 2.7 2.9 4 0 0 4 4 3 1 Unstructured conserved, between two C2H2-type zinc-fingers AAA_25 PF13481.6 KFH47010.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFH47010.1 - 0.015 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KFH47010.1 - 0.02 15.0 0.2 2 8.5 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KFH47010.1 - 0.033 14.3 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFH47010.1 - 0.034 14.5 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KFH47010.1 - 0.084 13.4 0.1 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.6 KFH47010.1 - 0.15 12.0 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain COX6A PF02046.15 KFH47011.1 - 3.9e-49 165.8 3.9 4.6e-49 165.6 3.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 KFH47012.1 - 2.7e-17 63.1 0.1 4.2e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KFH47012.1 - 5.9e-05 23.1 4.6 0.00017 21.6 4.6 1.8 1 1 0 1 1 1 1 GRF zinc finger GCV_T PF01571.21 KFH47013.1 - 4.2e-70 236.1 0.1 4e-69 232.8 0.1 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFH47013.1 - 5.7e-48 164.3 0.2 9.3e-48 163.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KFH47013.1 - 3.9e-21 74.8 0.4 3.9e-21 74.8 0.4 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KFH47013.1 - 5.5e-18 65.1 0.0 1.1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox PF00070.27 KFH47013.1 - 0.0003 21.3 0.1 0.085 13.4 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH47013.1 - 0.001 18.4 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFH47013.1 - 0.0052 15.7 0.1 0.073 11.9 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 KFH47013.1 - 0.0073 16.6 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 KFH47013.1 - 0.0087 15.2 0.2 0.025 13.7 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KFH47013.1 - 0.019 14.2 0.4 1.9 7.6 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain SoxG PF04268.12 KFH47013.1 - 0.03 14.5 0.0 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Sarcosine oxidase, gamma subunit family NAD_binding_9 PF13454.6 KFH47013.1 - 0.033 14.2 0.2 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4562 PF15123.6 KFH47013.1 - 0.036 14.0 0.3 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) ThiF PF00899.21 KFH47013.1 - 0.049 13.0 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KFH47013.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KFH47013.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GPI2 PF06432.11 KFH47015.1 - 2.8e-129 430.5 0.2 3.2e-129 430.3 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4006 PF13179.6 KFH47015.1 - 0.089 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF4293 PF14126.6 KFH47015.1 - 0.13 12.5 0.6 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Intg_mem_TP0381 PF09529.10 KFH47015.1 - 0.16 11.5 2.8 0.63 9.5 0.1 2.6 3 0 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) MPC PF03650.13 KFH47016.1 - 4.8e-36 123.2 0.2 8.3e-36 122.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KFH47016.1 - 0.037 14.1 0.2 0.055 13.5 0.2 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF5363 PF17320.2 KFH47016.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5363) CNH PF00780.22 KFH47017.1 - 5.5e-64 216.4 0.0 8.3e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KFH47017.1 - 2.4e-34 119.2 0.3 3.9e-34 118.5 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KFH47017.1 - 2.6e-12 47.0 0.0 1e-11 45.1 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFH47017.1 - 0.0003 21.2 0.0 0.015 15.8 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 KFH47017.1 - 0.002 17.9 0.0 1 9.2 0.1 2.4 2 0 0 2 2 2 2 PH domain DUF3484 PF11983.8 KFH47017.1 - 5.1 8.3 7.8 11 7.3 3.3 3.6 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch IMS PF00817.20 KFH47018.1 - 1.1e-41 142.4 0.0 3.2e-41 140.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFH47018.1 - 8.1e-16 58.8 0.0 1.7e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KFH47018.1 - 1.6e-10 40.3 4.5 3.2e-10 39.4 4.5 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KFH47018.1 - 0.017 15.4 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif CDC24_OB3 PF17244.2 KFH47018.1 - 0.1 12.3 0.4 0.19 11.4 0.1 1.5 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 zf-C2H2 PF00096.26 KFH47018.1 - 0.34 11.4 3.0 0.85 10.2 3.0 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Thaumatin PF00314.17 KFH47019.1 - 1.9e-67 227.1 3.7 1.9e-67 227.1 3.7 1.6 2 0 0 2 2 2 1 Thaumatin family Glyco_hydro_64 PF16483.5 KFH47019.1 - 0.025 13.9 0.7 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase CIA30 PF08547.12 KFH47020.1 - 1.6e-44 151.7 0.0 2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF1687 PF07955.11 KFH47021.1 - 8.2e-33 113.6 0.1 1.1e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DAO PF01266.24 KFH47022.1 - 1.6e-33 116.8 0.1 2.3e-33 116.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFH47022.1 - 1.3e-07 31.7 0.2 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFH47022.1 - 5.3e-05 22.3 0.1 0.001 18.1 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KFH47022.1 - 0.00017 21.0 0.1 0.0036 16.6 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH47022.1 - 0.00072 19.7 0.1 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFH47022.1 - 0.0027 16.8 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFH47022.1 - 0.014 14.7 0.1 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KFH47022.1 - 0.029 14.6 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KFH47022.1 - 0.07 12.2 0.1 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KFH47022.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KFH47022.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TFIIS_C PF01096.18 KFH47023.1 - 2.1e-19 69.1 2.5 2.1e-19 69.1 2.5 2.6 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFH47023.1 - 1.6e-08 34.3 3.7 4.4e-08 32.9 0.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Desulfoferrod_N PF06397.12 KFH47023.1 - 0.00084 18.9 1.5 0.33 10.6 0.1 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 KFH47023.1 - 0.01 15.8 6.3 0.074 13.0 0.5 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain IBR PF01485.21 KFH47023.1 - 0.018 15.3 6.9 1.1 9.5 1.8 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_ribbon_recom PF13408.6 KFH47023.1 - 0.039 14.5 2.0 0.17 12.4 0.0 2.5 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-Nse PF11789.8 KFH47023.1 - 0.04 13.8 0.0 0.16 11.8 0.0 2.1 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Elf1 PF05129.13 KFH47023.1 - 0.16 12.1 3.2 1.1 9.4 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.17 KFH47023.1 - 3 7.7 5.3 7 6.6 0.7 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_L14e PF01929.17 KFH47024.1 - 4e-27 94.5 4.1 5.6e-27 94.0 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KFH47024.1 - 0.0011 18.9 1.5 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 KOW motif Hexokinase_2 PF03727.16 KFH47025.1 - 6.2e-78 261.5 0.0 9.7e-78 260.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFH47025.1 - 3.8e-73 245.6 0.0 6e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FA_desaturase PF00487.24 KFH47027.1 - 1.1e-24 87.7 23.9 2.1e-24 86.7 23.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFH47027.1 - 3.2e-05 24.1 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) NdhL PF10716.9 KFH47027.1 - 0.043 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit FlhE PF06366.13 KFH47028.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlhE ISN1 PF06437.11 KFH47030.1 - 1.2e-192 640.3 0.0 1.5e-192 640.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Aminotran_3 PF00202.21 KFH47031.1 - 3.6e-06 25.9 0.0 5.7e-06 25.2 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-III Pkinase PF00069.25 KFH47032.1 - 1.2e-09 37.9 0.0 0.00044 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain EthD PF07110.11 KFH47033.1 - 3.7e-20 72.9 1.0 4.7e-20 72.5 1.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFH47033.1 - 1e-06 29.2 0.1 1.9e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase zf_UBZ PF18439.1 KFH47037.1 - 0.5 10.0 2.3 2 8.1 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KFH47037.1 - 2 8.1 8.0 0.17 11.5 3.1 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.6 KFH47038.1 - 6.5e-08 32.3 5.5 1.2e-07 31.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH47038.1 - 8e-07 28.8 7.7 1.4e-06 28.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH47038.1 - 1.5e-06 28.1 6.2 1.5e-06 28.1 6.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH47038.1 - 6.1e-06 26.1 8.9 1.2e-05 25.2 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFH47038.1 - 1.2e-05 25.1 8.7 2.3e-05 24.2 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFH47038.1 - 2.5e-05 24.3 3.8 4.5e-05 23.5 3.8 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KFH47038.1 - 0.00018 21.8 7.0 0.00018 21.8 7.0 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KFH47038.1 - 0.0016 18.3 5.1 0.0028 17.5 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFH47038.1 - 0.0036 17.4 7.6 0.0093 16.1 7.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.24 KFH47038.1 - 0.014 15.3 2.8 0.038 13.9 2.8 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cript PF10235.9 KFH47038.1 - 0.016 15.8 3.3 0.037 14.6 2.2 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf_CCCH_4 PF18345.1 KFH47038.1 - 0.06 13.4 1.7 0.12 12.5 1.7 1.5 1 0 0 1 1 1 0 Zinc finger domain L51_S25_CI-B8 PF05047.16 KFH47039.1 - 1.5e-14 53.7 0.0 1.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ANTH PF07651.16 KFH47041.1 - 5.9e-79 264.9 0.1 5.9e-79 264.9 0.1 2.5 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KFH47041.1 - 5e-56 189.2 9.9 5e-56 189.2 9.9 6.0 4 1 3 7 7 7 2 I/LWEQ domain ENTH PF01417.20 KFH47041.1 - 0.0087 16.1 0.2 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.7 KFH47041.1 - 6.9 7.0 7.7 0.65 10.3 0.4 3.3 3 1 0 3 3 3 0 TcdB toxin N-terminal helical domain UPF0016 PF01169.19 KFH47043.1 - 1.3e-41 140.8 25.1 1.3e-20 73.5 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 KFH47043.1 - 0.16 12.4 0.5 20 5.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2070 PF09843.9 KFH47043.1 - 0.67 8.2 3.8 0.2 9.9 0.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) ADH_zinc_N PF00107.26 KFH47044.1 - 5.9e-26 91.0 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH47044.1 - 3.6e-20 71.9 0.8 6.3e-20 71.1 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH47044.1 - 4.1e-10 40.8 0.0 5.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BKACE PF05853.12 KFH47044.1 - 0.00096 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme 2-Hacid_dh_C PF02826.19 KFH47044.1 - 0.014 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFH47044.1 - 0.025 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFH47045.1 - 5.9e-41 139.8 0.0 2.6e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 KFH47046.1 - 3.4e-89 293.5 0.5 6.6e-17 61.9 0.0 7.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH47046.1 - 2.3e-73 241.7 7.8 1.6e-10 41.3 0.0 10.0 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH47046.1 - 1.5e-67 215.5 4.8 1.1e-05 25.4 0.0 15.1 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 KFH47046.1 - 1.6e-65 214.9 18.8 6.1e-06 26.5 0.1 14.3 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 KFH47046.1 - 2e-57 190.5 21.3 5.2e-09 36.2 0.1 13.2 3 2 10 14 14 14 13 Ankyrin repeats (many copies) DNA_pol_B PF00136.21 KFH47048.1 - 8.8e-103 344.5 0.0 1.2e-102 344.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFH47048.1 - 3e-24 85.8 0.0 2.8e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFH47048.1 - 2.3e-18 66.4 4.0 2.3e-18 66.4 4.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta zf-FPG_IleRS PF06827.14 KFH47048.1 - 0.27 11.1 6.5 0.11 12.4 3.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UBX PF00789.20 KFH47049.1 - 2.7e-15 56.3 0.0 5.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.12 KFH47049.1 - 1.3 7.6 11.6 1.6 7.3 11.6 1.1 1 0 0 1 1 1 0 Hamartin protein Neur_chan_memb PF02932.16 KFH47049.1 - 4.3 7.3 7.3 6.9 6.7 7.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 KFH47049.1 - 5.4 7.0 16.8 8.5 6.4 16.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med19 PF10278.9 KFH47049.1 - 6.5 6.6 17.7 12 5.8 17.7 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Isy1 PF06246.12 KFH47050.1 - 0.022 14.4 0.4 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Isy1-like splicing family DIT1_PvcA PF05141.12 KFH47050.1 - 0.088 12.3 0.3 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein ACPS PF01648.20 KFH47051.1 - 2e-08 34.4 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily S4 PF01479.25 KFH47053.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KFH47053.1 - 4.7e-06 27.4 0.0 8.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Sas10_Utp3 PF04000.15 KFH47054.1 - 1.4e-14 54.4 1.2 1.4e-14 54.4 1.2 2.6 2 1 0 2 2 2 1 Sas10/Utp3/C1D family UPF0184 PF03670.13 KFH47054.1 - 0.049 14.0 0.5 0.049 14.0 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) XRN_M PF17846.1 KFH47054.1 - 0.21 10.5 7.4 0.25 10.2 7.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain NPV_P10 PF05531.12 KFH47054.1 - 0.36 11.3 3.1 0.41 11.1 0.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UQ_con PF00179.26 KFH47056.1 - 1.4e-47 160.8 0.0 1.6e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH47056.1 - 0.0045 16.7 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFH47056.1 - 0.0052 16.6 0.1 0.0096 15.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KFH47056.1 - 0.023 15.0 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain PI-PLC-X PF00388.19 KFH47057.1 - 9.7e-56 187.4 0.0 1.7e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFH47057.1 - 2.3e-40 137.5 0.0 3.9e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RST PF12174.8 KFH47057.1 - 0.032 14.2 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SURF1 PF02104.15 KFH47058.1 - 3.2e-48 164.3 0.0 4.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 SURF1 family dsDNA_bind PF01984.20 KFH47060.1 - 5.6e-42 142.5 12.0 6.6e-42 142.3 12.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 KFH47060.1 - 0.31 11.6 3.4 0.16 12.6 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) ATP-sulfurylase PF01747.17 KFH47061.1 - 1.9e-86 289.0 0.1 2.7e-86 288.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFH47061.1 - 3.5e-57 192.7 0.0 5.2e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KFH47061.1 - 7.5e-55 184.9 0.0 1.5e-54 183.9 0.0 1.5 2 0 0 2 2 2 1 PUA-like domain KTI12 PF08433.10 KFH47061.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mpv17_PMP22 PF04117.12 KFH47063.1 - 1e-07 32.1 0.1 1e-07 32.1 0.1 2.5 2 1 0 2 2 2 1 Mpv17 / PMP22 family RRM_1 PF00076.22 KFH47064.1 - 0.0023 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.22 KFH47064.1 - 0.96 8.6 10.0 1.2 8.2 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KFH47064.1 - 2 7.1 5.3 2.7 6.7 5.3 1.1 1 0 0 1 1 1 0 Presenilin Glyco_hydro_43 PF04616.14 KFH47065.1 - 1.1e-16 61.0 13.8 1e-07 31.6 3.2 3.8 3 1 0 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFH47065.1 - 0.034 13.7 3.7 0.049 13.2 0.2 2.4 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain Metallophos PF00149.28 KFH47066.1 - 1.1e-13 52.2 0.1 1.6e-13 51.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH47066.1 - 2.3e-10 40.9 0.0 1.8e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EOS1 PF12326.8 KFH47067.1 - 1.6e-16 60.8 5.7 4e-16 59.5 1.8 2.2 1 1 1 2 2 2 1 N-glycosylation protein PEPcase PF00311.17 KFH47067.1 - 0.43 8.6 2.7 1.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase PAM2 PF07145.15 KFH47068.1 - 0.002 17.7 12.3 0.24 11.2 0.3 3.7 3 0 0 3 3 3 2 Ataxin-2 C-terminal region Ribosomal_L12_N PF16320.5 KFH47068.1 - 5.7 6.7 8.6 0.11 12.2 0.3 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain MMM1 PF10296.9 KFH47069.1 - 4.2e-06 26.0 0.6 1.7e-05 24.1 0.1 2.0 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Dabb PF07876.12 KFH47070.1 - 1.2e-07 32.3 0.0 1.3e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.18 KFH47071.1 - 6.3e-06 25.4 0.2 1.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.19 KFH47072.1 - 9.7e-17 61.2 3.0 1.5e-16 60.5 3.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFH47072.1 - 1.4e-06 28.8 1.2 3e-06 27.7 1.2 1.6 1 0 0 1 1 1 1 HMG-box domain CcmH PF03918.14 KFH47074.1 - 0.16 11.2 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein YIF1 PF03878.15 KFH47075.1 - 5.6e-100 333.8 2.0 6.6e-100 333.6 2.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KFH47075.1 - 1.7 8.3 13.0 0.74 9.5 10.3 1.7 1 1 1 2 2 2 0 Yip1 domain CENP-T_C PF15511.6 KFH47076.1 - 1.6e-40 137.6 0.0 3.2e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFH47076.1 - 4.2e-08 33.4 0.0 8.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFH47076.1 - 2.4e-06 27.9 0.0 2.4e-06 27.9 0.0 2.6 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFH47076.1 - 0.0046 17.2 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KFH47076.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ADC PF06314.11 KFH47077.1 - 0.00069 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HSP70 PF00012.20 KFH47078.1 - 1.6e-10 39.9 0.2 4.7e-09 35.0 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFH47078.1 - 0.0068 15.3 0.2 0.041 12.7 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.25 KFH47079.1 - 8.4e-65 218.7 0.0 1.5e-64 217.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47079.1 - 4e-31 108.2 0.0 7.8e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KFH47079.1 - 6.9e-21 74.6 0.1 1.6e-10 41.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH47079.1 - 4.2e-19 68.7 0.0 1.7e-09 38.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH47079.1 - 6e-14 50.8 0.0 0.011 16.2 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFH47079.1 - 2.1e-13 50.2 1.8 1.2e-05 25.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH47079.1 - 5.6e-12 45.5 0.3 0.014 15.8 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat AAA_16 PF13191.6 KFH47079.1 - 2.1e-09 38.0 4.2 1.3e-08 35.4 0.3 3.2 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KFH47079.1 - 1.6e-06 28.2 0.4 4.8e-06 26.6 0.4 1.9 1 0 0 1 1 1 1 NACHT domain Kinase-like PF14531.6 KFH47079.1 - 5.1e-06 26.0 0.0 2.2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like AAA_22 PF13401.6 KFH47079.1 - 0.00016 22.0 0.1 0.00047 20.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain Pkinase_fungal PF17667.1 KFH47079.1 - 0.00053 18.9 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase AAA_30 PF13604.6 KFH47079.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFH47079.1 - 0.042 13.0 0.0 0.098 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Tim44 PF04280.15 KFH47080.1 - 9.4e-11 42.0 4.6 1.8e-10 41.1 2.2 2.3 2 1 0 2 2 2 1 Tim44-like domain MBA1 PF07961.11 KFH47080.1 - 0.005 15.9 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Dimeth_Pyl PF09505.10 KFH47080.1 - 0.026 13.1 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Mt_ATP-synt_D PF05873.12 KFH47081.1 - 1.1e-20 74.1 2.2 1.3e-20 73.8 2.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.9 KFH47081.1 - 0.00083 19.9 0.5 0.026 15.1 0.1 2.2 1 1 1 2 2 2 1 T5orf172 domain DUF4201 PF13870.6 KFH47081.1 - 0.015 15.1 2.8 0.17 11.6 2.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF948 PF06103.11 KFH47081.1 - 0.23 11.8 2.0 1.7 8.9 0.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 KFH47081.1 - 0.31 11.6 2.4 0.64 10.6 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 KFH47081.1 - 0.56 10.3 7.8 2.4 8.2 0.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ank_3 PF13606.6 KFH47083.1 - 4e-09 36.0 0.1 0.014 15.8 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KFH47083.1 - 1.1e-08 35.5 0.0 3.1e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH47083.1 - 5.9e-08 33.1 0.0 2.4e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH47083.1 - 1.7e-07 31.3 0.1 0.09 13.1 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH47083.1 - 3.3e-07 30.5 0.0 0.055 13.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat DUF3447 PF11929.8 KFH47083.1 - 0.12 12.3 0.0 5.6 7.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) ANAPC5 PF12862.7 KFH47084.1 - 9.7e-33 112.1 3.4 9.7e-33 112.1 3.4 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KFH47084.1 - 0.0079 16.5 0.3 8.1 6.9 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat Type_III_YscG PF09477.10 KFH47084.1 - 0.021 14.9 0.9 1.2 9.2 0.0 3.1 3 0 0 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_21 PF09976.9 KFH47084.1 - 0.026 14.2 1.8 1.2 8.8 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 KFH47084.1 - 0.17 12.4 14.1 10 6.7 0.3 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFH47084.1 - 1.9 8.8 5.3 5.4 7.4 0.6 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFH47084.1 - 4.4 8.0 11.8 20 5.9 0.1 4.8 4 2 0 4 4 4 0 Tetratricopeptide repeat Ring_hydroxyl_A PF00848.19 KFH47085.1 - 1.5e-25 90.4 5.1 6.1e-13 49.2 0.2 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KFH47085.1 - 1.7e-15 56.7 0.0 3.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Acetyltransf_1 PF00583.25 KFH47086.1 - 0.0058 16.9 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GBS_Bsp-like PF08481.10 KFH47086.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 GBS Bsp-like repeat MATalpha_HMGbox PF04769.12 KFH47087.1 - 5.9e-61 205.3 0.0 7.8e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box IBN_N PF03810.19 KFH47088.1 - 1.1e-15 57.3 2.2 9.1e-14 51.1 0.2 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFH47088.1 - 2.9e-08 32.9 0.1 1.6e-07 30.5 0.0 2.1 2 1 0 2 2 2 1 Cse1 Xpo1 PF08389.12 KFH47088.1 - 3.3e-05 24.0 1.8 0.00074 19.6 0.1 3.8 3 0 0 3 3 3 1 Exportin 1-like protein GRIP PF01465.20 KFH47088.1 - 0.031 14.2 0.5 0.25 11.3 0.1 2.9 2 0 0 2 2 2 0 GRIP domain Vac14_Fab1_bd PF12755.7 KFH47088.1 - 0.38 11.4 1.6 5.5 7.6 0.1 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region UPF0242 PF06785.11 KFH47088.1 - 0.4 10.8 6.2 1.2 9.2 6.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3385 PF11865.8 KFH47088.1 - 1.8 8.5 4.5 27 4.6 0.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) HET PF06985.11 KFH47090.1 - 1.8e-12 47.9 0.0 2.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.21 KFH47091.1 - 5.2e-43 147.2 0.0 8.5e-28 97.1 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III VASt PF16016.5 KFH47093.1 - 3.1e-36 125.1 0.0 5.9e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFH47093.1 - 1.6e-23 82.8 0.0 2.5e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain COA2 PF17051.5 KFH47094.1 - 0.0016 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 NUDIX PF00293.28 KFH47095.1 - 3.3e-07 30.4 0.0 8.8e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 KFH47096.1 - 2.6e-22 79.2 0.3 4.6e-22 78.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47096.1 - 1.3e-10 41.3 8.5 2.2e-10 40.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MelC1 PF06236.11 KFH47096.1 - 0.17 12.0 0.4 1 9.4 0.2 2.1 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 ADH_N PF08240.12 KFH47097.1 - 5.7e-26 90.5 2.3 1.6e-25 89.1 2.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH47097.1 - 1.9e-14 53.8 1.3 1.1e-13 51.3 1.3 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH47097.1 - 2.6e-09 36.9 0.3 0.00014 21.4 0.1 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFH47097.1 - 0.0019 17.5 0.3 0.0044 16.3 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KFH47097.1 - 0.0046 16.5 0.1 0.0096 15.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KFH47097.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 KFH47097.1 - 0.025 14.8 0.5 0.14 12.4 0.5 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N_2 PF13602.6 KFH47097.1 - 0.036 15.1 0.0 0.08 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF281 PF03436.13 KFH47097.1 - 0.056 13.9 0.1 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Shikimate_DH PF01488.20 KFH47097.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFH47097.1 - 0.2 11.5 0.4 0.33 10.8 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2418 PF10332.9 KFH47098.1 - 8e-37 125.7 0.1 1.9e-36 124.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) PALP PF00291.25 KFH47099.1 - 2.6e-76 256.9 0.2 3.8e-76 256.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KFH47099.1 - 9.5e-35 118.3 0.0 9.2e-19 67.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase vMSA PF00695.19 KFH47099.1 - 0.026 13.6 0.3 0.038 13.1 0.3 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Syndecan PF01034.20 KFH47100.1 - 0.5 10.3 2.3 4 7.4 1.0 2.4 2 0 0 2 2 2 0 Syndecan domain BCIP PF13862.6 KFH47101.1 - 3.1e-67 226.3 0.0 3.9e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein E1-E2_ATPase PF00122.20 KFH47102.1 - 1e-33 116.4 19.1 1.3e-27 96.5 0.1 4.0 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFH47102.1 - 7.5e-19 68.1 7.8 7.5e-19 68.1 7.8 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFH47102.1 - 8.2e-19 68.7 0.0 2.3e-15 57.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFH47102.1 - 1e-15 57.6 0.0 2.7e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFH47102.1 - 2.8e-15 55.8 0.0 8.4e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFH47102.1 - 0.0077 16.0 0.4 0.016 15.0 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 KFH47102.1 - 0.061 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Glyco_hydro_76 PF03663.14 KFH47103.1 - 1.6e-16 60.8 0.0 9.6e-16 58.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Cyclin_N PF00134.23 KFH47104.1 - 2.9e-05 23.8 0.0 0.00055 19.7 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain PIRT PF15099.6 KFH47105.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family LapA_dom PF06305.11 KFH47105.1 - 0.059 13.2 0.8 0.088 12.6 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Syndecan PF01034.20 KFH47105.1 - 0.071 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF3318 PF11780.8 KFH47105.1 - 0.078 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) TraL PF07178.11 KFH47105.1 - 0.083 13.4 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 TraL protein DUF2062 PF09835.9 KFH47105.1 - 0.084 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Gypsy PF07253.11 KFH47105.1 - 0.12 10.8 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein EphA2_TM PF14575.6 KFH47105.1 - 0.14 13.0 0.0 0.22 12.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4349 PF14257.6 KFH47105.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TNFR_16_TM PF18422.1 KFH47105.1 - 0.22 11.5 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Fungal_trans PF04082.18 KFH47106.1 - 1.4e-18 66.9 0.0 3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47106.1 - 3.8e-08 33.3 11.8 6.4e-08 32.6 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KFH47106.1 - 0.026 14.5 23.6 0.054 13.5 23.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 KFH47106.1 - 0.71 9.0 6.0 1 8.5 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5427 PF10310.9 KFH47107.1 - 7.5e-175 582.4 0.9 9e-175 582.1 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) PCuAC PF04314.13 KFH47107.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.4 3 0 0 3 3 3 0 Copper chaperone PCu(A)C CPSase_L_D2 PF02786.17 KFH47108.1 - 3.2e-113 376.4 0.3 6.5e-84 280.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFH47108.1 - 2.2e-47 160.1 0.0 5e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KFH47108.1 - 1.3e-44 151.8 0.0 3.5e-44 150.4 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KFH47108.1 - 1.9e-44 151.7 0.1 9.2e-44 149.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KFH47108.1 - 3.9e-39 133.8 0.0 9.9e-39 132.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KFH47108.1 - 9.5e-23 81.0 0.0 1.5e-21 77.1 0.0 2.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KFH47108.1 - 8.6e-20 70.7 0.0 4.4e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KFH47108.1 - 1.6e-18 67.0 0.6 4.9e-09 36.0 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFH47108.1 - 1.9e-17 63.3 0.1 6.6e-09 35.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFH47108.1 - 3.6e-10 39.7 0.0 3.5e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFH47108.1 - 5.1e-06 26.6 0.5 0.021 14.8 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KFH47108.1 - 1.8e-05 24.6 0.2 0.031 14.1 0.0 4.2 4 0 0 4 4 4 1 DJ-1/PfpI family GARS_A PF01071.19 KFH47108.1 - 2.1e-05 24.4 0.1 0.13 12.0 0.0 3.4 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KFH47108.1 - 3.8e-05 23.4 0.0 0.015 14.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.13 KFH47108.1 - 0.0033 17.2 0.2 0.29 10.8 0.2 2.8 1 1 0 1 1 1 1 Peptidase C26 Glyco_hydro_92 PF07971.12 KFH47110.1 - 6.4e-127 424.3 0.0 8e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFH47110.1 - 4e-47 161.1 1.4 6e-47 160.5 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF3622 PF12286.8 KFH47110.1 - 0.059 13.7 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) Endonuclease_5 PF04493.14 KFH47110.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Endonuclease V IBR PF01485.21 KFH47111.1 - 4.2e-06 26.9 4.1 4.2e-06 26.9 4.1 4.3 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain DUF411 PF04214.13 KFH47111.1 - 0.045 13.7 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF Baculo_IE-1 PF05290.11 KFH47111.1 - 3.5 7.6 11.5 1.2e+02 2.6 11.2 2.9 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Pkinase PF00069.25 KFH47112.1 - 5.5e-67 225.9 0.0 6.9e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47112.1 - 3.5e-31 108.4 0.0 4.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH47112.1 - 1.5e-05 24.2 0.1 2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFH47112.1 - 4.9e-05 22.8 0.1 0.00032 20.1 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH47112.1 - 0.00043 20.3 0.1 0.0011 18.9 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH47112.1 - 0.0017 17.8 0.0 0.048 13.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KFH47112.1 - 0.022 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFH47112.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CDC45 PF02724.14 KFH47113.1 - 7.2e-250 830.7 0.0 4e-249 828.2 0.0 2.6 1 1 0 1 1 1 1 CDC45-like protein FAM60A PF15396.6 KFH47113.1 - 8.7 6.3 9.6 0.23 11.4 2.3 1.8 2 0 0 2 2 2 0 Protein Family FAM60A MU117 PF15474.6 KFH47114.1 - 4.1e-10 40.4 0.2 6.8e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene family DUF4618 PF15397.6 KFH47115.1 - 0.00095 18.7 2.3 0.0017 17.8 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) FAR1 PF03101.15 KFH47115.1 - 0.0048 17.6 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Golgin_A5 PF09787.9 KFH47115.1 - 0.0069 15.9 2.4 0.011 15.2 2.4 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 CCDC158 PF15921.5 KFH47115.1 - 0.016 13.1 0.5 0.021 12.7 0.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 HIP1_clath_bdg PF16515.5 KFH47115.1 - 0.033 14.8 2.8 0.033 14.8 2.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 KFH47115.1 - 0.077 13.3 4.9 0.51 10.7 3.6 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KFH47115.1 - 0.095 13.3 2.4 7.1 7.3 3.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nnf1 PF03980.14 KFH47115.1 - 0.16 12.4 5.6 0.25 11.8 4.6 1.8 1 1 0 1 1 1 0 Nnf1 Med9 PF07544.13 KFH47115.1 - 0.18 11.9 6.1 0.54 10.4 6.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ZapD PF07072.11 KFH47115.1 - 0.19 11.4 2.9 0.4 10.4 2.9 1.4 1 0 0 1 1 1 0 Cell division protein FlgM PF04316.13 KFH47115.1 - 0.31 11.4 3.5 1.1 9.7 3.5 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM SKA2 PF16740.5 KFH47115.1 - 0.36 10.6 4.7 0.38 10.6 2.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 KFH47115.1 - 0.57 9.0 6.4 0.22 10.4 3.4 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Mt_ATP-synt_D PF05873.12 KFH47115.1 - 2.2 8.1 6.6 0.3 10.9 2.2 1.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) MeaB PF03308.16 KFH47116.1 - 2.3e-05 23.5 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KFH47116.1 - 0.00018 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFH47116.1 - 0.00026 21.4 0.0 0.00063 20.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KFH47116.1 - 0.00044 19.6 0.0 0.00062 19.1 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PRK PF00485.18 KFH47116.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFH47116.1 - 0.001 19.6 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFH47116.1 - 0.0015 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 KFH47116.1 - 0.0029 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFH47116.1 - 0.0033 17.4 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 KFH47116.1 - 0.0043 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase NACHT PF05729.12 KFH47116.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KFH47116.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.14 KFH47116.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KFH47116.1 - 0.025 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFH47116.1 - 0.037 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH47116.1 - 0.045 14.3 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KFH47116.1 - 0.054 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain hNIFK_binding PF12196.8 KFH47116.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK AAA_31 PF13614.6 KFH47116.1 - 0.06 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFH47116.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KFH47116.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 KFH47116.1 - 0.074 13.1 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 KFH47116.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_14 PF13173.6 KFH47116.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFH47116.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KFH47116.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFH47116.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBP_BcsQ PF06564.12 KFH47116.1 - 0.15 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_23 PF13476.6 KFH47116.1 - 0.17 12.4 0.0 0.5 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KFH47117.1 - 3.1e-113 378.5 0.4 3.6e-113 378.3 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFH47117.1 - 1.2e-15 57.4 0.4 5.4e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFH47117.1 - 0.00015 21.2 0.1 0.091 12.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFH47117.1 - 0.0038 17.5 0.4 1.3 9.3 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KFH47117.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KFH47117.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PMSR PF01625.21 KFH47119.1 - 9.5e-61 204.4 0.0 1.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF1774 PF08611.10 KFH47120.1 - 1.3e-38 131.1 3.2 1.3e-38 131.1 3.2 2.8 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) Avl9 PF09794.9 KFH47121.1 - 4.4e-141 470.0 0.0 5.5e-141 469.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KFH47121.1 - 1.7e-06 28.0 0.0 0.00024 21.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KFH47121.1 - 1.2e-05 25.1 0.6 0.0017 18.0 0.0 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Solute_trans_a PF03619.16 KFH47122.1 - 1.6e-99 332.7 10.3 1.9e-99 332.5 10.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha L_protein_N PF15518.6 KFH47122.1 - 0.19 11.6 0.4 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 L protein N-terminus DUF1387 PF07139.11 KFH47122.1 - 1 9.0 3.0 1.5 8.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Flagellin_C PF00700.21 KFH47123.1 - 0.011 16.1 0.1 0.075 13.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region adh_short PF00106.25 KFH47124.1 - 9.1e-26 90.5 0.0 1.2e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH47124.1 - 1.3e-24 87.1 0.0 1.6e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH47124.1 - 1.9e-07 31.2 0.1 4.9e-07 29.8 0.1 1.7 1 1 0 1 1 1 1 KR domain Profilin PF00235.19 KFH47125.1 - 0.061 13.6 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 Profilin Sec5 PF15469.6 KFH47126.1 - 3.6e-37 128.0 0.0 2.3e-36 125.4 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 KFH47126.1 - 7.4e-05 22.8 0.5 0.00047 20.2 0.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Oxidored_FMN PF00724.20 KFH47127.1 - 1.5e-45 156.0 0.0 1.8e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MTHFR PF02219.17 KFH47127.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Cellulase-like PF12876.7 KFH47127.1 - 0.056 12.8 0.0 18 4.5 0.0 2.8 3 0 0 3 3 3 0 Sugar-binding cellulase-like NMO PF03060.15 KFH47127.1 - 0.076 12.4 0.8 0.41 10.0 0.1 2.1 1 1 1 3 3 3 0 Nitronate monooxygenase ATP-synt_F PF01990.17 KFH47129.1 - 1.9e-29 101.8 0.4 3.9e-15 55.9 0.1 2.1 2 0 0 2 2 2 2 ATP synthase (F/14-kDa) subunit Transglut_core PF01841.19 KFH47130.1 - 1.1e-09 38.8 0.0 2.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gp_dh_C PF02800.20 KFH47131.1 - 2.7e-72 241.5 0.0 3.8e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFH47131.1 - 2.2e-38 130.7 0.1 5.2e-38 129.4 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KFH47131.1 - 0.0016 18.5 0.4 0.008 16.3 0.2 2.3 2 1 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus VP4_helical PF17478.2 KFH47131.1 - 0.016 14.6 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Rotavirus VP4 helical domain 2-Hacid_dh_C PF02826.19 KFH47131.1 - 0.048 13.0 0.1 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AhpC-TSA_2 PF13911.6 KFH47132.1 - 1.2e-05 25.4 0.1 2.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme PBP1_TM PF14812.6 KFH47132.1 - 0.83 10.1 6.9 6.8 7.1 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.29 KFH47133.1 - 4.3e-08 32.9 8.8 9.2e-08 31.9 8.8 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KFH47133.1 - 2.6e-05 24.7 0.0 7.6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 SET domain Mito_carr PF00153.27 KFH47134.1 - 5.8e-56 186.4 3.3 2.2e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_4 PF00953.21 KFH47135.1 - 3.4e-28 98.6 7.8 3.4e-28 98.6 7.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2107 PF09880.9 KFH47135.1 - 3.7 7.7 6.0 0.4 10.8 0.2 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) p450 PF00067.22 KFH47136.1 - 1.6e-75 254.6 0.0 1.9e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CR6_interact PF10147.9 KFH47136.1 - 0.095 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 AFG1_ATPase PF03969.16 KFH47137.1 - 4.3e-95 318.7 0.0 1.2e-90 304.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KFH47137.1 - 7e-05 23.3 0.0 0.019 15.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 KFH47137.1 - 0.0019 18.1 0.0 0.93 9.3 0.0 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 KFH47137.1 - 0.0046 17.2 0.0 0.043 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFH47137.1 - 0.044 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 KFH47137.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA PF00004.29 KFH47137.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_1_4 PF13692.6 KFH47138.1 - 7.3e-05 23.2 0.0 0.00048 20.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFH47138.1 - 0.00076 19.9 0.1 0.002 18.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Malic_M PF03949.15 KFH47139.1 - 2.4e-86 289.2 0.0 3.3e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFH47139.1 - 1.1e-65 220.9 0.0 1.6e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TFIIIC_delta PF12657.7 KFH47140.1 - 3.1e-21 76.1 0.0 1.6e-20 73.8 0.0 2.3 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFH47140.1 - 4.6e-11 42.6 0.4 1e-10 41.5 0.4 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Pyrid_ox_like PF16242.5 KFH47141.1 - 2.2e-24 85.7 0.1 3.3e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KFH47141.1 - 4.5e-08 33.2 0.0 8.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KFH47141.1 - 0.033 13.9 0.1 0.056 13.2 0.0 1.4 1 1 0 1 1 1 0 Putative FMN-binding domain Metallophos PF00149.28 KFH47143.1 - 1.9e-30 106.9 0.1 8.1e-22 78.7 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFH47143.1 - 0.03 14.7 0.1 0.077 13.5 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-C2H2_jaz PF12171.8 KFH47144.1 - 3e-08 33.7 0.5 5.9e-08 32.8 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFH47144.1 - 4.2e-05 23.8 0.5 8.6e-05 22.8 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFH47144.1 - 0.003 17.6 0.1 0.007 16.5 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger SNRNP27 PF08648.12 KFH47144.1 - 0.0037 17.3 0.7 0.0037 17.3 0.7 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 KFH47144.1 - 0.16 12.5 0.5 0.36 11.4 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFH47144.1 - 0.16 12.1 2.0 0.27 11.4 2.0 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger TP53IP5 PF15331.6 KFH47144.1 - 1.6 8.9 11.9 0.32 11.1 5.5 2.0 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Fungal_trans PF04082.18 KFH47145.1 - 3.2e-18 65.7 0.0 5.5e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47145.1 - 7.1e-09 35.6 9.9 1.2e-08 34.9 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KFH47146.1 - 8e-06 26.1 6.0 8e-06 26.1 6.0 3.3 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KFH47146.1 - 1.9e-05 24.9 1.4 5.1e-05 23.5 1.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFH47146.1 - 2.3e-05 24.2 3.4 2.3e-05 24.2 3.4 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFH47146.1 - 0.00021 21.1 4.8 0.00023 20.9 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFH47146.1 - 0.0003 20.6 4.9 0.0003 20.6 4.9 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH47146.1 - 0.0013 18.6 3.0 0.0013 18.6 3.0 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFH47146.1 - 0.0015 18.5 0.4 0.0015 18.5 0.4 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFH47146.1 - 0.0017 18.1 1.1 0.0017 18.1 1.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 KFH47146.1 - 0.027 13.2 1.5 0.041 12.5 1.5 1.2 1 0 0 1 1 1 0 Pellino zf-ANAPC11 PF12861.7 KFH47146.1 - 1.1 9.4 6.7 0.15 12.1 2.3 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FAD_binding_7 PF03441.14 KFH47147.1 - 1.1e-81 273.1 0.1 1.7e-81 272.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFH47147.1 - 1.8e-40 138.7 0.1 2.7e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KFH47147.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein family Clr5 PF14420.6 KFH47149.1 - 0.00026 21.1 0.1 0.00073 19.7 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain DivIC PF04977.15 KFH47149.1 - 0.0053 16.5 5.8 0.14 11.9 0.5 2.3 2 0 0 2 2 2 1 Septum formation initiator Wtap PF17098.5 KFH47149.1 - 0.0075 16.2 6.8 0.022 14.7 6.8 1.8 1 1 0 1 1 1 1 WTAP/Mum2p family Sec34 PF04136.15 KFH47149.1 - 0.015 15.2 1.7 0.096 12.6 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family CENP-Q PF13094.6 KFH47149.1 - 0.022 14.9 5.0 0.022 14.9 5.0 3.2 3 1 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.21 KFH47149.1 - 0.032 14.3 12.5 0.77 9.9 4.9 2.6 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 KFH47149.1 - 0.035 14.8 6.4 7.8 7.2 1.9 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Lebercilin PF15619.6 KFH47149.1 - 0.036 13.7 1.0 0.036 13.7 1.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 KFH47149.1 - 0.061 13.3 12.5 0.66 10.0 1.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SOGA PF11365.8 KFH47149.1 - 0.076 14.2 7.3 0.32 12.1 3.4 2.9 2 0 0 2 2 2 0 Protein SOGA APG6_N PF17675.1 KFH47149.1 - 0.086 13.4 8.0 1.8 9.1 1.4 2.7 3 0 0 3 3 2 0 Apg6 coiled-coil region RmuC PF02646.16 KFH47149.1 - 0.094 11.8 2.8 6.1 5.9 0.1 2.2 2 0 0 2 2 2 0 RmuC family KASH_CCD PF14662.6 KFH47149.1 - 0.11 12.3 6.1 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 KFH47149.1 - 0.12 12.5 9.4 1.2 9.2 5.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 KFH47149.1 - 0.2 11.8 9.9 2.8 8.2 9.9 2.3 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 KFH47149.1 - 0.35 11.3 7.8 3.5 8.1 2.9 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF812 PF05667.11 KFH47149.1 - 0.44 9.4 5.9 1.2 8.0 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.9 KFH47149.1 - 0.48 10.3 11.2 2.7 7.9 0.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 KFH47149.1 - 0.63 10.0 10.3 6.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 KFH47149.1 - 0.9 8.4 7.6 1.1 8.0 2.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4446 PF14584.6 KFH47149.1 - 0.91 9.5 6.0 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) RasGAP_C PF03836.15 KFH47149.1 - 1.1 9.4 5.5 1.7 8.8 1.3 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Dor1 PF04124.12 KFH47149.1 - 1.4 7.5 5.7 26 3.3 3.2 2.7 2 1 0 2 2 2 0 Dor1-like family Rootletin PF15035.6 KFH47149.1 - 1.8 8.6 9.0 6 6.8 2.0 2.7 3 0 0 3 3 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 KFH47149.1 - 1.8 9.2 19.9 0.31 11.7 1.1 4.2 4 0 0 4 4 4 0 SlyX DHR10 PF18595.1 KFH47149.1 - 2 8.5 15.9 0.53 10.4 7.5 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4164 PF13747.6 KFH47149.1 - 2.1 8.7 10.6 0.19 12.0 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3450 PF11932.8 KFH47149.1 - 2.4 7.4 8.8 9.6 5.4 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CASP_C PF08172.12 KFH47149.1 - 2.6 7.3 10.6 0.18 11.1 0.9 2.9 3 0 0 3 3 2 0 CASP C terminal FlaC_arch PF05377.11 KFH47149.1 - 2.6 8.5 6.5 2.1 8.8 1.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 KFH47149.1 - 3.2 7.4 11.4 1 9.1 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SHE3 PF17078.5 KFH47149.1 - 3.9 7.1 9.6 6.3 6.5 1.0 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KFH47149.1 - 3.9 7.5 12.1 11 6.1 3.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 KFH47149.1 - 4.4 6.0 5.3 17 4.1 2.0 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.11 KFH47149.1 - 4.7 7.5 7.4 28 5.0 0.4 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KxDL PF10241.9 KFH47149.1 - 4.7 7.6 11.6 6.6 7.1 3.0 2.8 3 0 0 3 3 2 0 Uncharacterized conserved protein betaPIX_CC PF16523.5 KFH47149.1 - 5.6 6.9 8.0 3.7 7.4 2.3 2.4 2 0 0 2 2 2 0 betaPIX coiled coil DUF4407 PF14362.6 KFH47149.1 - 5.9 6.2 7.7 0.55 9.5 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 KFH47149.1 - 6.5 7.2 11.8 11 6.5 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tektin PF03148.14 KFH47149.1 - 6.9 5.3 9.3 11 4.7 0.6 2.2 2 0 0 2 2 2 0 Tektin family Fungal_TACC PF12709.7 KFH47149.1 - 8.7 6.9 8.9 10 6.7 0.3 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Jnk-SapK_ap_N PF09744.9 KFH47149.1 - 9 6.5 11.7 2.1 8.6 0.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 KFH47149.1 - 9.2 6.8 9.0 18 5.8 0.5 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DivIVA PF05103.13 KFH47149.1 - 9.7 6.3 12.0 2.5 8.2 0.7 2.6 2 0 0 2 2 2 0 DivIVA protein Slx4 PF09494.10 KFH47150.1 - 1.9e-25 88.6 0.0 3e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.19 KFH47150.1 - 2e-05 23.9 30.3 0.1 12.5 4.4 4.9 3 0 0 3 3 3 3 AT hook motif HLH PF00010.26 KFH47151.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 KFH47152.1 - 1.5e-81 274.6 9.7 1.7e-81 274.4 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH47152.1 - 5.3e-30 104.5 36.5 1.6e-27 96.4 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFH47152.1 - 3.1e-06 26.0 10.2 0.00011 20.9 2.7 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KFH47152.1 - 2e-05 23.3 3.6 2.6e-05 22.9 1.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) cNMP_binding PF00027.29 KFH47155.1 - 1.4e-34 118.0 0.0 9.7e-19 67.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KFH47155.1 - 1.8e-33 116.2 14.6 1.8e-33 116.2 14.6 2.9 3 0 0 3 3 3 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 KFH47155.1 - 5.2e-11 41.7 3.0 0.048 13.7 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KFH47155.1 - 7.9e-07 29.3 0.3 0.051 14.0 0.0 4.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH47155.1 - 1e-05 25.4 2.0 12 6.9 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.33 KFH47155.1 - 2.4e-05 24.1 0.5 2.4e-05 24.1 0.5 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFH47155.1 - 2.6e-05 24.0 0.5 0.0001 22.1 0.5 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KFH47155.1 - 0.058 13.2 0.2 18 5.2 0.0 3.5 3 2 0 3 3 3 0 Leucine rich repeat PSCyt3 PF07627.11 KFH47155.1 - 0.3 11.4 1.2 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) SUIM_assoc PF16619.5 KFH47155.1 - 2.7 8.1 9.7 12 6.1 9.7 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 2-Hacid_dh_C PF02826.19 KFH47156.1 - 2.3e-46 157.4 0.0 2e-45 154.3 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH47156.1 - 0.00015 21.4 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SAP PF02037.27 KFH47156.1 - 0.18 11.6 1.5 32 4.4 0.1 3.5 3 0 0 3 3 3 0 SAP domain Vps5 PF09325.10 KFH47157.1 - 1.7e-10 40.9 0.9 2.6e-10 40.3 0.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KFH47157.1 - 1e-08 35.1 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 KFH47157.1 - 0.006 16.8 1.7 0.038 14.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ECM11 PF15463.6 KFH47158.1 - 5.1e-43 146.8 9.3 1.1e-42 145.8 9.3 1.6 1 0 0 1 1 1 1 Extracellular mutant protein 11 Suppressor_APC PF11414.8 KFH47158.1 - 1 9.5 4.9 2.1 8.4 4.9 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CSN5_C PF18323.1 KFH47158.1 - 1.1 10.3 3.9 12 6.8 3.9 2.7 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Methyltransf_16 PF10294.9 KFH47160.1 - 3.8e-13 49.5 0.0 1.2e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase DJ-1_PfpI PF01965.24 KFH47162.1 - 4.3e-16 59.2 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KFH47162.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MitMem_reg PF13012.6 KFH47164.1 - 3.5e-12 46.7 0.6 7.8e-12 45.6 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFH47164.1 - 1.2e-09 38.2 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TFIIS_C PF01096.18 KFH47165.1 - 1.2e-15 57.1 1.4 1.2e-15 57.1 1.4 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFH47165.1 - 1.9e-05 24.4 9.3 0.00055 19.7 2.5 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Spt4 PF06093.13 KFH47165.1 - 0.0027 17.8 1.9 0.0078 16.3 1.9 1.8 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger tRNA-synt_1f PF01921.18 KFH47165.1 - 0.028 13.3 0.8 0.034 13.1 0.3 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (K) Zn_Tnp_IS1 PF03811.13 KFH47165.1 - 0.032 13.9 2.9 0.062 13.0 0.1 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Zn_Tnp_IS1595 PF12760.7 KFH47165.1 - 0.032 14.2 0.6 0.032 14.2 0.6 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 KFH47165.1 - 0.08 12.7 0.9 0.08 12.7 0.9 3.3 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger C1_1 PF00130.22 KFH47165.1 - 0.45 10.4 9.1 0.23 11.4 1.1 2.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.17 KFH47165.1 - 0.48 10.2 0.1 0.48 10.2 0.1 3.0 3 1 0 3 3 3 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.10 KFH47165.1 - 0.66 10.1 13.5 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 KFH47165.1 - 5.7 6.7 15.8 0.35 10.6 3.8 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KFH47165.1 - 6.8 6.8 12.5 6.8 6.8 0.1 2.6 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABC_tran PF00005.27 KFH47166.1 - 6.2e-49 166.0 0.0 4.3e-29 101.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFH47166.1 - 6.9e-39 134.1 24.0 2.1e-21 76.8 13.4 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFH47166.1 - 4e-10 39.5 0.7 0.0036 16.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH47166.1 - 6.6e-08 33.3 2.4 0.0004 20.9 0.0 3.4 3 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFH47166.1 - 4.5e-07 29.5 1.2 0.018 14.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KFH47166.1 - 2.8e-06 27.1 0.1 0.057 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFH47166.1 - 1.4e-05 25.1 0.1 6.2 6.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFH47166.1 - 4.3e-05 23.5 0.2 0.098 12.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFH47166.1 - 0.00013 22.3 3.1 0.24 11.8 0.0 3.5 4 0 0 4 4 2 2 AAA ATPase domain AAA_22 PF13401.6 KFH47166.1 - 0.00016 21.9 0.8 0.83 9.9 0.3 3.2 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KFH47166.1 - 0.00032 20.0 0.7 2.6 7.2 0.0 3.7 4 0 0 4 4 4 1 NB-ARC domain NACHT PF05729.12 KFH47166.1 - 0.00071 19.5 0.5 0.79 9.6 0.0 2.7 3 0 0 3 3 2 2 NACHT domain DUF87 PF01935.17 KFH47166.1 - 0.00093 19.3 3.4 0.0042 17.2 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 KFH47166.1 - 0.0012 18.5 1.1 0.67 9.5 0.4 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KFH47166.1 - 0.0012 19.0 0.1 2.1 8.7 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KFH47166.1 - 0.0016 18.5 0.2 0.073 13.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFH47166.1 - 0.0054 16.5 0.0 2.2 8.0 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KFH47166.1 - 0.0057 15.7 1.7 0.97 8.4 0.1 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein Pox_A32 PF04665.12 KFH47166.1 - 0.011 15.2 4.4 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 KFH47166.1 - 0.014 14.8 0.1 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFH47166.1 - 0.039 13.7 0.1 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFH47166.1 - 0.05 13.5 0.6 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 NTPase Septin PF00735.18 KFH47166.1 - 0.052 12.8 0.1 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 KFH47166.1 - 0.059 13.1 0.1 4.5 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFH47166.1 - 0.061 13.5 0.5 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFH47166.1 - 0.074 12.3 0.2 0.74 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 KFH47166.1 - 0.075 12.9 0.5 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KFH47166.1 - 0.088 13.0 0.1 22 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KFH47166.1 - 0.13 11.8 0.2 2 7.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 KFH47166.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.23 KFH47166.1 - 0.17 11.9 3.3 4.1 7.4 0.2 2.4 2 0 0 2 2 2 0 Dynamin family CbiA PF01656.23 KFH47166.1 - 0.21 11.6 2.3 3.7 7.6 0.2 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.6 KFH47166.1 - 0.24 11.1 0.1 9.1 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFH47166.1 - 0.26 10.5 0.8 3.8 6.8 0.3 2.2 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KFH47166.1 - 0.47 10.2 1.9 7 6.4 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 KFH47166.1 - 1.1 8.4 2.7 13 4.8 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF3040 PF11239.8 KFH47166.1 - 7.8 6.9 10.1 6.1 7.2 1.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Hemerythrin PF01814.23 KFH47167.1 - 1.1e-09 39.0 0.6 1.5e-09 38.5 0.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ank_4 PF13637.6 KFH47168.1 - 1.1e-15 57.7 0.4 0.00054 20.5 0.0 6.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH47168.1 - 1.2e-13 51.4 0.4 0.00054 20.5 0.0 3.4 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH47168.1 - 3.3e-13 48.5 1.0 0.55 11.0 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFH47168.1 - 5.1e-12 45.8 2.6 0.004 17.4 0.1 5.2 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH47168.1 - 3.2e-07 30.5 1.0 2.3 8.8 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeat adh_short PF00106.25 KFH47169.1 - 1.5e-83 279.0 11.1 4.8e-45 153.4 2.3 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH47169.1 - 1.2e-66 224.7 5.9 4.7e-36 124.5 0.7 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KFH47169.1 - 6.8e-34 116.1 0.0 1.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KFH47169.1 - 1.2e-26 93.7 3.8 1.3e-13 51.2 0.3 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KFH47169.1 - 0.00025 20.4 0.4 0.019 14.3 0.3 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KFH47169.1 - 1.1 9.1 6.9 11 5.8 0.8 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 KFH47169.1 - 1.2 8.9 6.6 5.5 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase FAM25 PF15825.5 KFH47169.1 - 3.9 7.9 16.3 0.26 11.6 2.8 3.1 3 0 0 3 3 3 0 FAM25 family DUF4246 PF14033.6 KFH47170.1 - 9.5e-174 578.8 0.0 1.1e-173 578.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Phosphorylase PF00343.20 KFH47171.1 - 0 1054.7 0.0 0 1054.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase EF-hand_1 PF00036.32 KFH47172.1 - 3.3e-25 85.7 11.7 2.3e-08 33.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFH47172.1 - 8.8e-25 84.5 3.9 6e-06 25.8 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFH47172.1 - 5.5e-24 84.4 8.2 4.1e-15 56.0 0.8 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFH47172.1 - 1.6e-16 58.9 14.3 3.7e-05 23.0 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFH47172.1 - 1e-14 54.1 10.8 8.5e-06 25.5 0.6 3.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFH47172.1 - 3.9e-09 36.4 8.6 0.0038 17.1 0.2 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFH47172.1 - 6.3e-05 23.2 0.5 0.0067 16.7 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KFH47172.1 - 0.01 16.2 3.9 1.3 9.4 0.3 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KFH47172.1 - 0.023 13.6 0.3 2.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.11 KFH47172.1 - 0.07 13.3 0.2 2.3 8.4 0.0 2.9 3 1 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 KFH47172.1 - 0.14 12.6 1.8 12 6.3 0.0 3.6 3 1 1 4 4 4 0 EF-hand domain PMBR PF09373.10 KFH47172.1 - 0.18 12.0 0.0 16 5.8 0.0 3.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_10 PF14788.6 KFH47172.1 - 1.1 9.2 4.5 4.9 7.1 0.1 3.5 5 0 0 5 5 5 0 EF hand Methyltransf_23 PF13489.6 KFH47173.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47173.1 - 7.6e-09 36.2 0.0 6.9e-08 33.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47173.1 - 5.3e-08 33.5 0.0 1.6e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47173.1 - 8.1e-08 32.8 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH47173.1 - 1.2e-07 31.6 0.0 2.6e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFH47173.1 - 4.3e-05 23.7 0.0 0.00026 21.1 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KFH47173.1 - 0.0022 17.3 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KFH47173.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain UPF0146 PF03686.13 KFH47173.1 - 0.22 11.4 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) AAA_6 PF12774.7 KFH47174.1 - 3.7e-128 427.1 0.2 2.9e-127 424.2 0.0 2.8 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KFH47174.1 - 3.6e-116 389.0 5.7 3.6e-116 389.0 5.7 4.5 4 1 0 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KFH47174.1 - 8.3e-116 387.4 9.2 8.3e-116 387.4 9.2 6.5 7 1 0 8 8 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFH47174.1 - 1.1e-73 247.0 0.1 1.1e-73 247.0 0.1 3.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFH47174.1 - 1.1e-66 224.9 0.0 1.8e-65 220.9 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KFH47174.1 - 4e-42 143.8 0.0 6.2e-36 123.6 0.0 4.7 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KFH47174.1 - 1.6e-38 132.6 9.2 3.8e-38 131.4 9.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KFH47174.1 - 2.7e-30 105.2 0.0 1e-11 45.0 0.0 6.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFH47174.1 - 3.5e-30 104.5 0.1 7e-28 97.1 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFH47174.1 - 1.5e-28 99.6 0.0 3.9e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFH47174.1 - 2.1e-15 57.2 0.0 0.0094 16.2 0.0 5.6 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 KFH47174.1 - 4.3e-14 53.1 0.0 0.0011 19.4 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 KFH47174.1 - 6.6e-14 52.1 0.0 2.8e-13 50.1 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KFH47174.1 - 1e-11 45.5 0.3 1.6 9.0 0.0 7.7 7 0 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 KFH47174.1 - 2.2e-10 40.9 1.7 0.31 11.2 0.0 5.9 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 KFH47174.1 - 1.4e-09 38.6 0.2 0.072 13.6 0.0 5.7 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 KFH47174.1 - 2e-06 27.9 1.9 0.00017 21.7 0.0 3.9 4 0 0 4 4 2 1 AAA+ lid domain AAA_29 PF13555.6 KFH47174.1 - 9.2e-06 25.3 0.1 0.77 9.5 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KFH47174.1 - 2.4e-05 23.6 0.0 0.023 13.8 0.0 3.3 4 0 0 4 4 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 KFH47174.1 - 8.8e-05 23.0 1.2 6.1 7.4 0.0 5.5 4 0 0 4 4 4 0 ABC transporter AAA_14 PF13173.6 KFH47174.1 - 0.00034 20.6 0.0 2.9 7.9 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFH47174.1 - 0.00086 19.7 0.9 0.28 11.5 0.0 4.1 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KFH47174.1 - 0.0017 17.8 4.2 0.67 9.3 0.0 3.8 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFH47174.1 - 0.0028 17.3 0.0 0.19 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFH47174.1 - 0.0034 16.7 0.4 7.7 5.7 0.1 4.8 5 0 0 5 5 5 0 Zeta toxin AAA_30 PF13604.6 KFH47174.1 - 0.0037 17.0 4.1 37 3.9 0.3 5.7 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.18 KFH47174.1 - 0.0037 16.6 2.4 3.1 7.1 0.0 4.2 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_24 PF13479.6 KFH47174.1 - 0.0038 17.0 1.6 11 5.7 0.0 4.7 5 0 0 5 5 4 0 AAA domain Pil1 PF13805.6 KFH47174.1 - 0.0041 16.6 0.4 0.0041 16.6 0.4 3.1 2 0 0 2 2 2 1 Eisosome component PIL1 IstB_IS21 PF01695.17 KFH47174.1 - 0.0061 16.3 0.4 0.71 9.6 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFH47174.1 - 0.0072 16.7 0.6 44 4.5 0.0 4.8 5 0 0 5 5 4 0 RNA helicase Rad17 PF03215.15 KFH47174.1 - 0.064 13.2 0.0 6.7 6.6 0.0 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain Hemerythrin PF01814.23 KFH47174.1 - 0.095 13.3 0.0 2.4 8.8 0.0 3.6 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain DUF4482 PF14818.6 KFH47174.1 - 0.11 13.4 9.6 28 5.6 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NACHT PF05729.12 KFH47174.1 - 1.4 8.8 6.1 32 4.4 0.1 4.4 4 0 0 4 4 3 0 NACHT domain DUF3867 PF12983.7 KFH47174.1 - 1.4 8.9 11.7 2.8 7.9 4.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3867) DUF1843 PF08898.10 KFH47174.1 - 5.3 7.6 7.2 1.2e+02 3.3 0.0 4.2 4 0 0 4 4 2 0 Domain of unknown function (DUF1843) AtuA PF07287.11 KFH47177.1 - 3.3e-135 450.3 0.8 4e-135 450.1 0.8 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Ras PF00071.22 KFH47178.1 - 3.9e-42 143.6 0.0 8.5e-42 142.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFH47178.1 - 3.5e-30 104.7 0.0 5.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH47178.1 - 2.9e-10 39.9 0.0 2.1e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH47178.1 - 0.00039 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFH47178.1 - 0.00088 19.0 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KFH47178.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KFH47178.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFH47178.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFH47178.1 - 0.028 14.3 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFH47178.1 - 0.033 14.7 0.1 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 KFH47178.1 - 0.056 13.7 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFH47178.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH47178.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KFH47178.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ACPS PF01648.20 KFH47180.1 - 9.5e-09 35.4 0.1 1.7e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cullin PF00888.22 KFH47181.1 - 1e-195 652.0 9.8 1.4e-195 651.6 9.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFH47181.1 - 4e-26 90.8 4.7 4e-26 90.8 4.7 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KFH47181.1 - 0.093 13.3 3.4 0.17 12.4 0.5 3.1 4 0 0 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal FAD_SOX PF18371.1 KFH47181.1 - 0.55 10.6 3.4 2.2 8.7 0.1 3.7 4 0 0 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase E1_DerP2_DerF2 PF02221.15 KFH47182.1 - 5.5e-29 101.3 0.2 6.5e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 ML domain Bax1-I PF01027.20 KFH47183.1 - 1.5e-35 122.9 7.9 2.5e-35 122.2 7.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 zf-BED PF02892.15 KFH47184.1 - 0.11 12.6 0.9 0.28 11.2 0.9 1.7 1 0 0 1 1 1 0 BED zinc finger TRAF6_Z2 PF18048.1 KFH47184.1 - 0.12 12.5 0.9 0.23 11.6 0.9 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_6 PF13912.6 KFH47184.1 - 0.51 10.4 1.6 2 8.5 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.18 KFH47184.1 - 7.5 6.8 13.9 0.36 11.0 8.1 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosidase_ig PF17786.1 KFH47185.1 - 7.8e-13 48.8 0.2 2.6e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFH47185.1 - 1.6e-10 41.6 0.0 4.2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFH47185.1 - 4.6e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KFH47185.1 - 9.5e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFH47185.1 - 0.022 13.9 0.2 0.049 12.7 0.2 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain His_Phos_1 PF00300.22 KFH47186.1 - 3.7e-06 26.8 0.5 0.44 10.2 0.0 3.7 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) DUF1993 PF09351.10 KFH47187.1 - 1.5e-44 151.9 0.0 1.7e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) SH3_9 PF14604.6 KFH47188.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KFH47188.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SKG6 PF08693.10 KFH47188.1 - 0.31 10.5 0.1 0.31 10.5 0.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Potass_KdpF PF09604.10 KFH47188.1 - 4.4 7.4 5.9 11 6.1 5.9 1.7 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Cation_efflux PF01545.21 KFH47189.1 - 4e-46 157.3 5.7 5.5e-46 156.8 5.7 1.2 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_17 PF00332.18 KFH47190.1 - 2.5e-06 27.3 0.6 4.7e-06 26.4 0.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_cc PF11790.8 KFH47190.1 - 0.019 14.5 0.3 0.036 13.6 0.3 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Peptidase_C13 PF01650.18 KFH47192.1 - 1.6e-41 142.5 0.1 2.2e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ADH_zinc_N PF00107.26 KFH47194.1 - 7.8e-23 80.9 0.1 1.3e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFH47194.1 - 2.5e-21 75.6 0.0 4.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KFH47194.1 - 1.1e-06 29.7 0.0 2.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF89 PF01937.19 KFH47194.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 TP_methylase PF00590.20 KFH47195.1 - 2.2e-24 86.6 0.0 3.6e-24 85.9 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SpoVAD PF07451.11 KFH47195.1 - 0.033 12.9 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ribosomal_L14 PF00238.19 KFH47196.1 - 1e-32 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cupredoxin_1 PF13473.6 KFH47197.1 - 0.00086 19.4 0.1 0.0021 18.2 0.0 1.6 2 0 0 2 2 2 1 Cupredoxin-like domain DNA_pol_phi PF04931.13 KFH47197.1 - 0.31 9.1 5.1 0.38 8.8 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KFH47197.1 - 0.7 9.6 9.2 0.94 9.2 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KFH47197.1 - 0.93 8.8 6.9 1.2 8.4 6.9 1.2 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 KFH47197.1 - 1.3 9.5 10.5 0.36 11.2 6.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AF-4 PF05110.13 KFH47197.1 - 2.6 6.0 6.5 3.2 5.7 6.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UQ_con PF00179.26 KFH47198.1 - 8.4e-35 119.4 0.0 9.3e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM131 PF15010.6 KFH47198.1 - 0.17 11.7 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative cell signalling Cupin_8 PF13621.6 KFH47199.1 - 4.5e-35 121.6 0.0 1.2e-34 120.2 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain WD40 PF00400.32 KFH47199.1 - 3.9e-28 97.1 9.8 5.1e-06 27.1 0.8 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47199.1 - 2.7e-08 34.0 0.2 0.22 11.8 0.0 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH47199.1 - 0.00014 20.7 5.4 0.84 8.2 0.0 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Cupin_4 PF08007.12 KFH47199.1 - 0.00031 20.3 0.1 0.018 14.5 0.0 3.1 3 0 0 3 3 3 1 Cupin superfamily protein JmjC PF02373.22 KFH47199.1 - 0.0007 20.0 0.0 0.0033 17.9 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Ribosomal_S21e PF01249.18 KFH47200.1 - 3.6e-40 136.0 0.1 4e-40 135.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.16 KFH47201.1 - 1e-45 156.2 40.2 1e-45 156.2 40.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH47201.1 - 1.3e-16 60.6 6.9 1.3e-16 60.6 6.9 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFH47201.1 - 0.031 12.6 7.7 0.035 12.4 3.2 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2512 PF10710.9 KFH47201.1 - 8.3 6.1 8.2 4.4 7.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2512) CoA_transf_3 PF02515.17 KFH47202.1 - 5.2e-129 430.5 0.0 6e-129 430.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Acetyltransf_8 PF13523.6 KFH47202.1 - 0.087 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF5 PF04855.12 KFH47203.1 - 1.1e-92 310.2 0.0 1.4e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KFH47203.1 - 1.6e-05 24.4 1.2 4.1e-05 23.1 1.2 1.8 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KFH47203.1 - 0.25 11.1 4.8 0.21 11.3 1.6 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Fungal_trans PF04082.18 KFH47205.1 - 1.1e-14 54.2 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47205.1 - 4.3e-06 26.7 12.7 6.9e-06 26.1 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KFH47205.1 - 8.1 6.3 13.8 15 5.4 13.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBFD_NFYB_HMF PF00808.23 KFH47206.1 - 1.6e-27 95.6 0.4 1.9e-26 92.1 1.2 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFH47206.1 - 6.3e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KFH47206.1 - 0.00071 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KFH47206.1 - 0.0018 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KFH47206.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KFH47206.1 - 0.067 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Cmc1 PF08583.10 KFH47208.1 - 8.2e-16 57.8 4.2 9.7e-16 57.6 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SURF4 PF02077.15 KFH47209.1 - 1e-94 317.1 10.3 5.8e-74 249.0 5.7 2.0 2 0 0 2 2 2 2 SURF4 family Med16 PF11635.8 KFH47210.1 - 2.8e-66 224.0 0.0 3.3e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 TMEM154 PF15102.6 KFH47211.1 - 0.00041 20.3 0.7 0.00096 19.1 0.7 1.6 1 0 0 1 1 1 1 TMEM154 protein family Kelch_4 PF13418.6 KFH47211.1 - 0.0016 18.4 3.1 0.16 12.0 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Podoplanin PF05808.11 KFH47211.1 - 0.0017 18.5 1.5 0.0017 18.5 1.5 2.0 2 0 0 2 2 2 1 Podoplanin Amnionless PF14828.6 KFH47211.1 - 0.0024 16.8 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless Kelch_5 PF13854.6 KFH47211.1 - 0.011 15.7 0.0 9.5 6.3 0.0 3.9 4 0 0 4 4 4 0 Kelch motif MtrF PF09472.10 KFH47211.1 - 0.084 12.3 1.3 0.18 11.3 1.3 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF2615 PF11027.8 KFH47211.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Cadherin_C_2 PF16492.5 KFH47211.1 - 0.11 13.3 0.0 0.4 11.5 0.0 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Mucin PF01456.17 KFH47211.1 - 5.5 7.0 16.5 17 5.4 16.5 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans_2 PF11951.8 KFH47213.1 - 5.1e-84 282.3 0.8 7.1e-84 281.8 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47213.1 - 1.7e-07 31.2 4.8 3e-07 30.4 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCR PF12273.8 KFH47214.1 - 6.8e-19 68.7 13.6 1.1e-18 68.0 13.6 1.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 KFH47214.1 - 0.026 14.5 0.2 0.043 13.8 0.2 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Rhabdo_glycop PF00974.18 KFH47214.1 - 0.054 11.9 0.6 0.073 11.5 0.6 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein stn_TNFRSF12A PF12191.8 KFH47214.1 - 0.26 11.5 1.8 0.48 10.6 1.8 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Ammonium_transp PF00909.21 KFH47215.1 - 8.7e-119 396.8 25.3 1e-118 396.6 25.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4131 PF13567.6 KFH47215.1 - 4.9 6.8 6.2 6.8 6.3 2.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DAD PF02109.16 KFH47216.1 - 1.4e-49 166.9 2.4 1.6e-49 166.7 2.4 1.1 1 0 0 1 1 1 1 DAD family Corona_S2 PF01601.16 KFH47217.1 - 1.8 6.9 18.2 2.4 6.5 18.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mon1 PF03164.14 KFH47219.1 - 1.1e-154 515.4 0.0 1.3e-154 515.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Prefoldin_2 PF01920.20 KFH47220.1 - 4.2e-26 91.0 4.6 4.9e-26 90.8 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PhaP_Bmeg PF09602.10 KFH47220.1 - 0.00048 20.1 0.5 0.028 14.4 0.1 2.1 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4757 PF15949.5 KFH47220.1 - 0.0073 16.8 1.4 0.01 16.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) Prefoldin PF02996.17 KFH47220.1 - 0.01 15.7 4.1 2.8 7.9 4.1 2.2 1 1 0 1 1 1 0 Prefoldin subunit CagS PF16707.5 KFH47220.1 - 0.031 14.3 0.8 0.037 14.0 0.8 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori OmpH PF03938.14 KFH47220.1 - 0.032 14.6 5.7 2.3 8.5 0.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Imm9 PF15587.6 KFH47220.1 - 0.047 13.4 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 9 DUF148 PF02520.17 KFH47220.1 - 0.067 13.3 3.4 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Cytochrom_B562 PF07361.11 KFH47220.1 - 0.18 12.5 5.2 0.32 11.7 0.9 2.1 2 0 0 2 2 2 0 Cytochrome b562 HhH-GPD PF00730.25 KFH47222.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Autophagy_act_C PF03987.15 KFH47223.1 - 3e-15 56.5 0.3 5.9e-15 55.6 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF1282 PF06930.12 KFH47224.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF4064 PF13273.6 KFH47224.1 - 0.0039 17.4 0.3 0.0045 17.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 KFH47224.1 - 0.044 13.5 0.5 0.053 13.2 0.5 1.0 1 0 0 1 1 1 0 Tetraspanin family SecE PF00584.20 KFH47224.1 - 0.56 10.2 5.6 3 7.9 0.0 2.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex LRR_6 PF13516.6 KFH47225.1 - 2.2e-11 42.9 5.2 5.3e-05 23.0 0.0 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KFH47225.1 - 1.3e-08 34.9 11.1 0.023 15.1 0.0 5.4 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH47225.1 - 3.1e-05 23.9 0.2 11 7.0 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KFH47225.1 - 0.00019 21.1 13.8 0.36 10.6 0.0 5.0 3 2 1 4 4 4 3 Leucine rich repeat Ank_2 PF12796.7 KFH47226.1 - 1.1e-41 141.3 0.9 2.5e-11 44.0 0.0 9.0 6 2 4 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH47226.1 - 1e-29 99.2 4.5 0.0039 17.6 0.0 12.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 KFH47226.1 - 1.5e-29 102.0 8.4 2.8e-06 27.8 0.0 10.4 9 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH47226.1 - 3.6e-26 90.9 6.2 0.0077 16.5 0.0 10.8 10 1 2 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 KFH47226.1 - 2.1e-22 78.5 10.1 0.0059 17.0 0.0 11.5 11 0 0 11 11 11 4 Ankyrin repeat Imm49 PF15575.6 KFH47226.1 - 0.024 14.4 0.1 12 5.6 0.0 3.0 2 1 0 2 2 2 0 Immunity protein 49 Proteasome PF00227.26 KFH47227.1 - 3e-47 160.6 0.0 2e-31 108.9 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFH47227.1 - 6.3e-11 41.7 0.7 9.1e-11 41.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COesterase PF00135.28 KFH47229.1 - 1.1e-85 288.5 0.0 9.6e-85 285.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH47229.1 - 0.00026 20.9 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH47229.1 - 0.031 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family TMEM154 PF15102.6 KFH47232.1 - 1.6e-06 28.1 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family MGC-24 PF05283.11 KFH47232.1 - 8e-06 26.4 1.8 8e-06 26.4 1.8 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 KFH47232.1 - 8.5e-05 22.2 0.8 0.00013 21.7 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 KFH47232.1 - 0.00037 20.7 0.6 0.00071 19.7 0.6 1.4 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 KFH47232.1 - 0.0015 19.4 0.0 0.0035 18.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 KFH47232.1 - 0.0039 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 DAP10 membrane protein Mid2 PF04478.12 KFH47232.1 - 0.0078 16.1 0.7 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF1180 PF06679.12 KFH47232.1 - 0.014 15.9 0.3 0.014 15.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.16 KFH47232.1 - 0.03 13.1 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 KFH47232.1 - 0.039 13.8 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Rifin TMEM51 PF15345.6 KFH47232.1 - 0.048 13.5 0.4 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DAG1 PF05454.11 KFH47232.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Phage_Coat_B PF05356.11 KFH47232.1 - 0.053 13.4 0.7 0.092 12.7 0.7 1.3 1 0 0 1 1 1 0 Phage Coat protein B Neur_chan_memb PF02932.16 KFH47232.1 - 0.1 12.6 0.1 0.25 11.3 0.0 1.7 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Insulin_TMD PF17870.1 KFH47232.1 - 0.12 12.5 0.6 0.29 11.2 0.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 KFH47232.1 - 0.21 11.9 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) NECFESHC PF16621.5 KFH47235.1 - 0.071 13.1 4.7 1.3 9.0 0.1 2.9 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 VPS9 PF02204.18 KFH47236.1 - 4.5e-31 107.2 0.1 7.6e-31 106.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFH47236.1 - 1.6e-16 60.3 0.2 3.4e-16 59.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KFH47236.1 - 9.3e-10 38.0 0.1 7.5e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 CUE domain Sod_Fe_C PF02777.18 KFH47237.1 - 1.4e-13 50.9 0.0 3.6e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain zf-C2H2 PF00096.26 KFH47238.1 - 2.2e-06 27.8 25.6 0.00047 20.5 0.5 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH47238.1 - 0.0028 18.4 0.7 0.0028 18.4 0.7 5.2 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFH47238.1 - 0.041 13.9 0.3 0.041 13.9 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger COX17 PF05051.13 KFH47239.1 - 4.1e-21 75.1 6.7 4.9e-21 74.8 6.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF4110 PF13422.6 KFH47241.1 - 2.5e-31 107.6 1.2 2.5e-31 107.6 1.2 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KFH47241.1 - 3.7e-25 87.7 17.5 4e-08 33.1 0.0 6.3 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFH47241.1 - 6e-23 80.6 12.3 1.9e-07 31.2 0.2 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFH47241.1 - 5.3e-16 58.2 2.0 3e-05 23.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KFH47241.1 - 1.4e-14 53.7 2.2 0.0034 17.6 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFH47241.1 - 2.6e-11 43.0 2.2 0.012 15.6 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KFH47241.1 - 4.3e-09 35.8 2.4 0.0082 15.7 0.1 4.9 4 1 0 4 4 4 2 Kelch motif ISG65-75 PF11727.8 KFH47241.1 - 0.0087 15.3 5.2 0.019 14.2 5.2 1.4 1 0 0 1 1 1 1 Invariant surface glycoprotein DivIC PF04977.15 KFH47241.1 - 1 9.2 10.0 0.73 9.6 4.3 2.7 3 0 0 3 3 3 0 Septum formation initiator Plasmodium_Vir PF05795.11 KFH47241.1 - 1.9 7.8 8.3 1.1 8.7 1.8 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DEAD PF00270.29 KFH47242.1 - 2.2e-22 79.7 0.0 4.5e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFH47242.1 - 8.6e-16 58.4 6.4 2.6e-15 56.9 6.4 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 KFH47242.1 - 4.5e-15 56.0 0.0 2.4e-12 47.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 KFH47242.1 - 8.8e-13 48.0 0.0 2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KFH47242.1 - 1.4e-08 34.9 0.0 3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KFH47242.1 - 0.00023 21.1 0.1 0.00063 19.7 0.1 1.8 1 0 0 1 1 1 1 HRDC domain PhoLip_ATPase_C PF16212.5 KFH47243.1 - 8.2e-67 225.6 14.3 8.2e-67 225.6 14.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFH47243.1 - 2.1e-24 85.0 0.8 1.3e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFH47243.1 - 5.3e-11 42.5 0.0 5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH47243.1 - 8.3e-10 39.3 0.1 3.9e-05 24.0 0.0 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFH47243.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFH47243.1 - 0.086 12.6 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HLH PF00010.26 KFH47244.1 - 7.6e-11 41.8 0.0 2.1e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cnn_1N PF07989.11 KFH47244.1 - 0.11 12.7 3.8 0.2 11.9 0.8 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 KFH47244.1 - 2.8 8.1 8.7 0.13 12.4 2.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor ResIII PF04851.15 KFH47246.1 - 4.3e-23 82.2 0.0 8.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH47246.1 - 3.3e-21 75.7 0.1 7.6e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH47246.1 - 1.1e-17 64.4 0.0 7.7e-17 61.6 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFH47246.1 - 7.6e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KFH47246.1 - 0.0023 18.2 0.0 0.0083 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATP-grasp_2 PF08442.10 KFH47246.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF1772 PF08592.11 KFH47247.1 - 2.1e-05 24.9 2.7 3.3e-05 24.2 2.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) zf-H2C2_5 PF13909.6 KFH47248.1 - 0.02 14.6 8.5 0.039 13.7 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFH47248.1 - 0.9 10.1 17.4 0.063 13.8 4.9 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIB PF00382.19 KFH47249.1 - 3e-30 104.1 0.0 1.7e-19 69.6 0.0 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFH47249.1 - 3.3e-11 42.5 3.3 5.7e-11 41.8 3.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KFH47249.1 - 0.0014 18.6 0.2 0.0042 17.1 0.0 1.8 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KFH47249.1 - 0.0016 18.5 0.0 0.95 9.6 0.0 2.9 2 1 1 3 3 3 1 Cyclin, C-terminal domain Spt20 PF12090.8 KFH47249.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Spt20 family zf-RRN7 PF11781.8 KFH47249.1 - 0.013 15.2 1.1 0.028 14.1 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF948 PF06103.11 KFH47249.1 - 0.019 15.2 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HTH_Tnp_ISL3 PF13542.6 KFH47249.1 - 0.034 13.6 0.0 0.95 8.9 0.0 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 Connexin50 PF03509.14 KFH47249.1 - 0.057 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Gap junction alpha-8 protein (Cx50) Trm112p PF03966.16 KFH47249.1 - 0.14 12.7 0.6 0.52 10.9 0.6 2.2 1 1 0 1 1 1 0 Trm112p-like protein Cyclin_N PF00134.23 KFH47249.1 - 0.18 11.5 1.8 0.21 11.4 0.1 1.9 3 0 0 3 3 3 0 Cyclin, N-terminal domain DSPn PF14671.6 KFH47251.1 - 8.1e-42 143.0 0.0 1.4e-39 135.7 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFH47251.1 - 2e-17 63.3 0.0 4.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFH47251.1 - 4.4e-06 26.4 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CwfJ_C_1 PF04677.15 KFH47252.1 - 2.8e-22 78.9 0.0 6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFH47252.1 - 2.2e-17 63.8 0.4 3.9e-17 63.0 0.4 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.28 KFH47252.1 - 0.055 14.0 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Ofd1_CTDD PF10637.9 KFH47253.1 - 1.5e-96 322.7 0.0 4.1e-91 304.9 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFH47253.1 - 2.1e-26 92.4 0.0 1.6e-25 89.6 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFH47253.1 - 2.1e-13 50.9 0.0 6.3e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.21 KFH47254.1 - 1.4e-144 482.2 30.6 1.8e-144 481.9 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFH47254.1 - 3.5e-39 134.8 30.2 4.3e-39 134.6 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KFH47255.1 - 4e-17 62.1 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47255.1 - 7.3e-09 35.6 11.1 1.3e-08 34.8 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GEMIN8 PF15348.6 KFH47255.1 - 0.077 13.3 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 PMP1_2 PF08114.11 KFH47256.1 - 0.0047 16.6 0.8 0.0089 15.8 0.8 1.3 1 0 0 1 1 1 1 ATPase proteolipid family TMEM132D_C PF15706.5 KFH47256.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Chordopox_A13L PF05961.11 KFH47256.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein COX4_pro_2 PF07835.12 KFH47256.1 - 1.6 8.9 3.1 2.8 8.1 3.1 1.3 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Methyltransf_15 PF09445.10 KFH47257.1 - 1.4e-45 154.8 0.0 2e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KFH47257.1 - 0.00078 19.1 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KFH47257.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DNA_methylase PF00145.17 KFH47257.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase tRNA_U5-meth_tr PF05958.11 KFH47257.1 - 0.21 10.5 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase zf-DNL PF05180.12 KFH47258.1 - 1.5e-24 85.7 0.2 2.1e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KFH47258.1 - 0.11 12.2 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger zf-H2C2_2 PF13465.6 KFH47258.1 - 9.2 6.9 9.2 3.2 8.4 3.9 2.7 1 1 2 3 3 3 0 Zinc-finger double domain CH PF00307.31 KFH47259.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Calponin homology (CH) domain Tmemb_14 PF03647.13 KFH47260.1 - 1.7e-24 86.4 5.2 1.9e-24 86.2 5.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KFH47260.1 - 0.082 13.2 1.8 0.64 10.3 1.8 2.3 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 bZIP_1 PF00170.21 KFH47261.1 - 0.037 14.1 7.6 0.11 12.6 7.6 1.8 1 1 0 1 1 1 0 bZIP transcription factor CUE PF02845.16 KFH47262.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 KFH47262.1 - 0.0085 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 Fungal_trans PF04082.18 KFH47263.1 - 3.1e-15 55.9 1.9 5e-15 55.3 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47263.1 - 1.7e-07 31.2 9.3 3e-07 30.4 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KFH47263.1 - 0.039 13.9 0.7 0.1 12.6 0.7 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Peptidase_C15 PF01470.17 KFH47264.1 - 2.3e-13 50.8 0.0 1.2e-07 32.2 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase RRM_1 PF00076.22 KFH47265.1 - 5.4e-19 67.8 0.2 9.7e-19 67.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH47265.1 - 5e-05 22.9 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH47265.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pox_A_type_inc PF04508.12 KFH47266.1 - 1.1 9.3 0.0 1.1 9.3 0.0 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 KFH47266.1 - 5.4 7.2 42.4 0.047 13.9 0.6 6.2 4 2 3 7 7 7 0 Fibrinogen alpha/beta chain family TPR_9 PF13371.6 KFH47267.1 - 0.01 16.0 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 KFH47268.1 - 6.2e-149 496.8 18.2 6.9e-149 496.6 18.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 KFH47268.1 - 0.02 14.8 0.2 0.33 10.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) HECT PF00632.25 KFH47268.1 - 0.067 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) STIMATE PF12400.8 KFH47269.1 - 5.5e-41 140.0 4.7 5.5e-41 140.0 4.7 1.6 2 0 0 2 2 2 1 STIMATE family CENP-B_dimeris PF09026.10 KFH47269.1 - 0.15 12.4 5.6 0.28 11.6 5.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GRASP55_65 PF04495.14 KFH47270.1 - 3.3e-45 153.8 0.0 1.7e-44 151.5 0.0 1.8 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFH47270.1 - 0.0002 21.1 0.0 0.078 12.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain TAP_C PF03943.13 KFH47272.1 - 9.4e-19 66.8 0.1 2.3e-18 65.6 0.1 1.7 2 0 0 2 2 2 1 TAP C-terminal domain NTF2 PF02136.20 KFH47272.1 - 2.6e-06 28.0 0.0 0.0012 19.4 0.0 2.6 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KFH47272.1 - 6.1e-05 23.3 0.0 0.00033 21.0 0.0 2.3 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 KFH47272.1 - 0.00098 18.9 0.1 0.0087 15.9 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 KFH47272.1 - 0.011 15.2 0.0 0.044 13.3 0.0 1.9 2 1 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 KFH47272.1 - 0.027 14.3 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat PH PF00169.29 KFH47273.1 - 1.8e-05 25.2 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KFH47273.1 - 7.7e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sortilin-Vps10 PF15902.5 KFH47274.1 - 4.4e-286 948.6 19.5 2.8e-149 497.7 8.7 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFH47274.1 - 2e-91 304.9 16.7 8.8e-47 159.6 5.0 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KFH47274.1 - 2.9e-08 32.5 38.5 2.9 8.3 0.6 12.1 11 0 0 11 11 11 5 BNR/Asp-box repeat PSII_BNR PF14870.6 KFH47274.1 - 0.0042 16.4 0.3 2.4 7.3 0.0 4.4 5 0 0 5 5 5 1 Photosynthesis system II assembly factor YCF48 DUF2561 PF10812.8 KFH47274.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) CHB_HEX_C PF03174.13 KFH47274.1 - 0.02 14.9 0.9 0.38 10.8 0.1 3.7 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 KFH47274.1 - 1.7 8.9 13.5 65 4.0 0.1 6.6 7 0 0 7 7 7 0 BNR-Asp box repeat Pkinase_Tyr PF07714.17 KFH47275.1 - 5.5e-06 25.9 0.5 3.9e-05 23.1 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KFH47275.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ASRT PF07100.11 KFH47275.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer Abhydrolase_6 PF12697.7 KFH47276.1 - 3.9e-23 83.2 3.9 7.4e-23 82.3 3.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH47276.1 - 2e-07 30.5 0.1 3.3e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH47276.1 - 9.9e-07 28.7 0.2 3.9e-06 26.7 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFH47276.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KFH47276.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFH47276.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M28 PF04389.17 KFH47277.1 - 2.3e-35 122.1 0.0 4.6e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFH47277.1 - 3.4e-07 30.2 0.1 1.3e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 V-ATPase_G PF03179.15 KFH47278.1 - 0.0015 19.1 7.4 0.0027 18.2 7.4 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YlqD PF11068.8 KFH47278.1 - 0.0036 17.7 2.6 0.0044 17.4 2.6 1.2 1 0 0 1 1 1 1 YlqD protein SesA PF17107.5 KFH47278.1 - 0.043 14.0 3.1 0.072 13.3 3.1 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases pPIWI_RE_REase PF18154.1 KFH47278.1 - 0.063 13.2 1.7 0.088 12.8 1.7 1.2 1 0 0 1 1 1 0 REase associating with pPIWI_RE DUF4778 PF16008.5 KFH47278.1 - 0.25 11.4 4.4 0.33 11.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Metal_resist PF13801.6 KFH47278.1 - 0.88 9.8 6.7 41 4.4 6.6 2.1 1 1 0 1 1 1 0 Heavy-metal resistance DUF1515 PF07439.11 KFH47278.1 - 2.3 8.3 7.8 3.1 7.9 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) RRM_1 PF00076.22 KFH47279.1 - 2.5e-09 36.8 0.0 6.6e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH47279.1 - 2.5e-06 27.1 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KFH47279.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.8 KFH47279.1 - 0.00077 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 KFH47279.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 KFH47279.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Dopey_N PF04118.14 KFH47280.1 - 7.3e-112 373.4 0.0 1.4e-111 372.5 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal HEAT_EZ PF13513.6 KFH47280.1 - 0.0023 18.4 2.9 4.2 8.0 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat Sod_Cu PF00080.20 KFH47281.1 - 2.7e-05 24.4 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Cytochrom_C1 PF02167.15 KFH47282.1 - 1.1e-92 309.7 0.0 1.4e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFH47282.1 - 0.005 17.1 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KFH47282.1 - 0.067 14.3 0.2 0.25 12.5 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c Methyltransf_31 PF13847.6 KFH47284.1 - 1.1e-29 103.2 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47284.1 - 1.2e-18 67.6 0.1 2e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47284.1 - 5.2e-15 55.9 0.0 9.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH47284.1 - 2.9e-13 49.7 0.2 5.4e-13 48.8 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFH47284.1 - 1.5e-10 41.1 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47284.1 - 1.7e-09 38.3 0.0 2.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFH47284.1 - 4.1e-06 26.7 0.1 7e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFH47284.1 - 1e-05 25.0 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KFH47284.1 - 0.00016 21.0 0.1 0.00022 20.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KFH47284.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFH47284.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFH47284.1 - 0.00062 19.3 0.1 0.00093 18.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KFH47284.1 - 0.00081 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 KFH47284.1 - 0.00081 18.9 0.0 0.0014 18.0 0.0 1.4 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_19 PF04672.12 KFH47284.1 - 0.0048 16.4 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl methyltransferase DOT1 PF08123.13 KFH47284.1 - 0.0052 16.3 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 GidB PF02527.15 KFH47284.1 - 0.0076 15.6 0.2 0.015 14.6 0.2 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G FtsJ PF01728.19 KFH47284.1 - 0.0078 16.3 0.5 0.016 15.3 0.5 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.17 KFH47284.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase ADH_zinc_N PF00107.26 KFH47284.1 - 0.067 13.2 0.1 0.25 11.3 0.0 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Met_10 PF02475.16 KFH47284.1 - 0.085 12.6 0.7 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Met-10+ like-protein GCD14 PF08704.10 KFH47284.1 - 0.096 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 KFH47284.1 - 0.12 12.4 0.4 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFH47284.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Radial_spoke_3 PF06098.11 KFH47285.1 - 0.19 11.0 11.6 0.29 10.4 11.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Presenilin PF01080.17 KFH47285.1 - 0.37 9.5 7.5 0.54 9.0 7.5 1.2 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 KFH47285.1 - 0.56 9.0 10.2 0.82 8.4 10.2 1.3 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 KFH47285.1 - 0.65 9.9 23.4 0.9 9.5 23.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WASH-7_C PF14746.6 KFH47285.1 - 0.79 9.4 6.7 1.4 8.6 6.7 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Glyco_hydro_36 PF17167.4 KFH47286.1 - 1.2e-62 212.0 0.0 2e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 KFH47286.1 - 5.9e-28 97.9 0.0 8.7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 KFH47286.1 - 3.3e-05 23.3 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF608 PF04685.13 KFH47286.1 - 0.058 12.6 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region CFEM PF05730.11 KFH47287.1 - 2.8e-10 40.1 10.9 3.7e-10 39.7 9.2 2.0 2 0 0 2 2 2 1 CFEM domain FAD_binding_4 PF01565.23 KFH47288.1 - 1.9e-22 79.5 0.8 4e-22 78.4 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH47288.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.7 KFH47289.1 - 0.0004 20.2 0.2 0.00079 19.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH47289.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box domain adh_short_C2 PF13561.6 KFH47290.1 - 9.8e-54 182.4 0.0 1.3e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH47290.1 - 8.2e-42 142.9 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH47290.1 - 1.9e-08 34.4 0.0 4.7e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 KR domain PALP PF00291.25 KFH47290.1 - 0.03 13.8 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 KFH47290.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 KFH47290.1 - 0.041 13.6 0.2 0.078 12.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.32 KFH47291.1 - 1.3e-15 57.5 14.8 0.0036 18.1 0.6 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47291.1 - 1.6e-08 34.8 0.0 0.011 16.0 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KFH47291.1 - 0.044 13.5 0.9 3.1 7.5 0.0 3.2 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 KFH47291.1 - 0.065 13.2 0.3 2.4 8.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1845 PF08900.11 KFH47291.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) TRP PF06011.12 KFH47292.1 - 8.2e-140 466.3 14.1 9.7e-140 466.0 14.1 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFH47292.1 - 3.3e-38 131.2 0.1 4.9e-38 130.6 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 KFH47292.1 - 0.055 13.7 1.4 0.63 10.2 0.0 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PMT PF02366.18 KFH47293.1 - 2.9e-84 282.5 16.4 5.6e-84 281.6 16.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFH47293.1 - 1e-69 234.1 5.5 1e-69 234.1 5.5 3.1 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFH47293.1 - 1.4e-21 77.2 2.3 2.9e-21 76.2 2.3 1.5 1 0 0 1 1 1 1 MIR domain RAMP4 PF06624.12 KFH47293.1 - 0.21 11.7 1.1 1.5 9.0 0.7 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 AAA PF00004.29 KFH47294.1 - 3.1e-40 137.6 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH47294.1 - 8.3e-07 28.7 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFH47294.1 - 8.1e-05 22.6 0.1 0.00062 19.8 0.0 2.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFH47294.1 - 0.00015 22.0 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KFH47294.1 - 0.00045 20.4 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFH47294.1 - 0.00053 20.4 0.1 0.014 15.8 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFH47294.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFH47294.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFH47294.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH47294.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFH47294.1 - 0.042 14.2 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KFH47294.1 - 0.05 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFH47294.1 - 0.058 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFH47294.1 - 0.098 12.4 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFH47294.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFH47294.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Asparaginase PF00710.20 KFH47295.1 - 3.4e-46 157.2 0.0 4.8e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFH47295.1 - 6.8e-20 71.4 0.0 2.1e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF202 PF02656.15 KFH47296.1 - 0.00072 19.9 2.3 0.00072 19.9 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ABC_tran_CTD PF16326.5 KFH47297.1 - 0.0018 18.5 0.5 0.0027 17.9 0.5 1.2 1 0 0 1 1 1 1 ABC transporter C-terminal domain Sugarporin_N PF11471.8 KFH47297.1 - 0.0057 16.6 2.2 0.0091 15.9 2.2 1.3 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Myosin_tail_1 PF01576.19 KFH47297.1 - 0.011 13.6 2.1 0.015 13.2 2.1 1.0 1 0 0 1 1 1 0 Myosin tail BicD PF09730.9 KFH47297.1 - 0.06 11.8 0.1 0.075 11.5 0.1 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4407 PF14362.6 KFH47297.1 - 0.17 11.2 0.9 0.22 10.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 KFH47297.1 - 0.18 11.9 7.4 0.25 11.5 7.4 1.2 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.19 KFH47297.1 - 0.33 8.8 1.0 0.43 8.5 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.12 KFH47297.1 - 0.52 10.3 2.6 0.97 9.4 0.4 2.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DNA_pol_phi PF04931.13 KFH47298.1 - 7.3e-201 669.2 25.8 1e-200 668.7 25.8 1.2 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KFH47298.1 - 0.0002 20.9 27.1 0.00045 19.7 27.1 1.5 1 0 0 1 1 1 1 SDA1 DUF29 PF01724.16 KFH47298.1 - 0.069 13.4 3.3 0.11 12.8 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function DUF29 DUF1676 PF07898.13 KFH47298.1 - 0.19 11.8 6.8 0.59 10.1 6.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) N36 PF11438.8 KFH47298.1 - 0.46 10.4 1.8 1.3 8.9 1.8 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Nop14 PF04147.12 KFH47298.1 - 0.57 8.3 26.0 0.56 8.4 24.3 1.8 2 0 0 2 2 2 0 Nop14-like family TFIIF_alpha PF05793.12 KFH47298.1 - 4.2 5.8 33.8 8.5 4.8 33.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glycos_transf_3 PF00591.21 KFH47299.1 - 7.6e-61 205.9 0.0 1.3e-60 205.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KFH47299.1 - 3.1e-12 46.2 0.1 6.4e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pcc1 PF09341.10 KFH47300.1 - 1.3e-30 105.4 1.3 2.2e-30 104.6 1.3 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 BUD22 PF09073.10 KFH47300.1 - 0.0043 16.5 0.4 0.0043 16.5 0.4 1.0 1 0 0 1 1 1 1 BUD22 Myco_haema PF05692.12 KFH47300.1 - 0.014 14.4 0.1 0.015 14.3 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma haemagglutinin SUIM_assoc PF16619.5 KFH47300.1 - 0.35 11.0 11.7 0.36 10.9 10.4 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRN3 PF05327.11 KFH47301.1 - 1.3e-164 548.9 0.0 1.6e-164 548.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Rhodanese PF00581.20 KFH47302.1 - 1e-12 48.5 0.0 1.9e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_47 PF01532.20 KFH47305.1 - 1.4e-168 561.6 0.0 1.6e-168 561.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NAD_binding_10 PF13460.6 KFH47306.1 - 1.1e-14 54.8 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFH47306.1 - 0.011 15.2 0.2 0.02 14.3 0.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KFH47306.1 - 0.013 15.2 1.0 0.02 14.7 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.13 KFH47306.1 - 0.084 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DRIM PF07539.12 KFH47307.1 - 5.4e-176 586.5 4.8 6.9e-128 427.7 0.0 3.4 2 1 1 3 3 3 2 Down-regulated in metastasis HEAT_2 PF13646.6 KFH47307.1 - 2.5e-05 24.6 1.9 9.9 6.6 0.0 7.6 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.22 KFH47307.1 - 8.9e-05 22.4 3.8 17 6.0 0.1 8.0 6 1 1 7 7 7 2 HEAT repeat Ribosomal_60s PF00428.19 KFH47307.1 - 0.014 16.0 0.4 0.068 13.8 0.4 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein UME PF08064.13 KFH47307.1 - 0.05 13.5 0.7 6.3 6.8 0.1 4.7 3 1 1 4 4 4 0 UME (NUC010) domain DUF3385 PF11865.8 KFH47307.1 - 0.081 12.8 0.1 13 5.7 0.1 3.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) KAR9 PF08580.10 KFH47308.1 - 2.2e-180 601.6 10.4 2.2e-180 601.6 10.4 2.3 2 1 0 2 2 2 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 KFH47308.1 - 0.013 14.7 4.0 0.3 10.2 0.0 2.9 2 1 1 3 3 3 0 PLU-1-like protein Syntaxin-6_N PF09177.11 KFH47308.1 - 0.1 13.2 11.6 2.9 8.5 0.5 4.3 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 KFH47308.1 - 0.15 12.2 2.7 7 6.8 0.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 KFH47308.1 - 0.24 11.0 5.0 4.1 6.9 0.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4618 PF15397.6 KFH47308.1 - 0.49 9.8 5.1 2.6 7.4 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Trimer_CC PF08954.11 KFH47308.1 - 1.1 8.8 4.2 9.2 5.9 0.4 4.0 3 0 0 3 3 3 0 Trimerisation motif Prefoldin_2 PF01920.20 KFH47308.1 - 1.6 8.7 4.7 33 4.5 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit MFS_1 PF07690.16 KFH47309.1 - 1.9e-41 142.2 54.6 1.1e-38 133.1 54.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH47309.1 - 6.3e-10 38.1 10.7 8.8e-10 37.6 10.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HeLo PF14479.6 KFH47311.1 - 3.2e-31 108.8 0.3 4.9e-29 101.7 0.0 2.8 2 1 1 3 3 3 2 Prion-inhibition and propagation Ribonuc_L-PSP PF01042.21 KFH47312.1 - 9.6e-41 138.6 0.0 1.3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 KFH47312.1 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Cortex-I_coil PF09304.10 KFH47313.1 - 0.19 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Acetyltransf_2 PF00797.17 KFH47314.1 - 1.1e-38 133.4 0.0 3.1e-36 125.4 0.0 2.1 1 1 1 2 2 2 2 N-acetyltransferase Popeye PF04831.13 KFH47315.1 - 0.86 9.8 4.5 2.2 8.4 4.5 1.8 1 0 0 1 1 1 0 Popeye protein conserved region Peptidase_S8 PF00082.22 KFH47316.1 - 9.8e-31 107.1 6.9 1.3e-30 106.7 6.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFH47316.1 - 1.6e-11 44.7 1.0 4.6e-10 40.0 1.0 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.32 KFH47317.1 - 2.6e-22 78.7 9.6 3.2e-07 30.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47317.1 - 2.7e-11 43.6 0.5 0.0012 19.1 0.0 5.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFH47317.1 - 0.051 12.5 0.0 0.89 8.4 0.0 2.7 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFH47317.1 - 0.092 12.7 6.5 0.49 10.4 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 KFH47317.1 - 0.12 12.3 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Fasciclin PF02469.22 KFH47318.1 - 3.8e-45 153.2 0.0 4e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain ATP-synt_F6 PF05511.11 KFH47318.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Grg1 PF11034.8 KFH47319.1 - 4.2e-32 110.2 11.7 4.7e-32 110.0 11.7 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 LEA_4 PF02987.16 KFH47319.1 - 0.53 10.4 10.2 0.94 9.6 4.4 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant protein CAS_CSE1 PF03378.15 KFH47320.1 - 1.2e-173 577.7 0.0 2.2e-173 576.8 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFH47320.1 - 3.3e-148 493.4 4.7 5.1e-148 492.8 4.7 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFH47320.1 - 2.3e-13 49.8 0.4 8.8e-13 48.0 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2309 PF10070.9 KFH47320.1 - 0.048 12.0 0.0 0.074 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Xpo1 PF08389.12 KFH47320.1 - 0.15 12.1 4.8 4.5 7.3 0.0 4.7 5 1 1 6 6 6 0 Exportin 1-like protein PEX-2N PF09263.10 KFH47321.1 - 0.086 13.2 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal MIG-14_Wnt-bd PF06664.12 KFH47321.1 - 0.12 11.6 10.0 0.013 14.7 2.6 2.5 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion Cyt-b5 PF00173.28 KFH47322.1 - 1.8e-17 63.2 0.2 2.7e-17 62.7 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Shadoo PF14999.6 KFH47322.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Citrate_bind PF16114.5 KFH47322.1 - 0.088 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Paramyxo_ncap PF00973.19 KFH47322.1 - 0.89 8.4 3.3 1.1 8.1 3.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Abhydrolase_6 PF12697.7 KFH47323.1 - 8.4e-15 56.0 0.0 1e-14 55.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH47323.1 - 6.2e-05 22.4 0.0 0.00013 21.4 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH47323.1 - 9.8e-05 22.1 0.0 0.0075 15.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFH47323.1 - 0.0007 18.6 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFH47323.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_8 PF06259.12 KFH47323.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase IBR PF01485.21 KFH47324.1 - 8e-21 74.0 32.6 2.5e-14 53.2 2.3 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KFH47324.1 - 1e-17 64.5 0.0 2.3e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 KFH47324.1 - 0.00021 21.0 7.0 0.00063 19.4 7.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFH47324.1 - 0.00022 21.2 6.1 0.00022 21.2 6.1 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 KFH47324.1 - 0.00041 20.6 7.8 0.00041 20.6 7.8 4.0 3 1 1 4 4 4 2 Ring finger domain zf-RING_5 PF14634.6 KFH47324.1 - 0.00043 20.2 4.7 0.00043 20.2 4.7 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFH47324.1 - 0.0035 17.5 2.6 0.0035 17.5 2.6 4.1 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFH47324.1 - 0.01 15.7 8.3 0.01 15.7 8.3 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH47324.1 - 6.7 6.7 33.3 0.46 10.4 5.0 4.2 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 GDPD PF03009.17 KFH47325.1 - 1.4e-14 54.5 0.0 2.3e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Kelch_3 PF13415.6 KFH47326.1 - 9.7e-17 60.8 4.6 3e-09 36.9 0.0 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFH47326.1 - 5.2e-16 58.4 0.3 4.3e-05 23.4 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFH47326.1 - 9.1e-15 54.3 1.9 6.3e-07 29.2 0.1 4.2 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 KFH47326.1 - 3.1e-13 49.1 0.0 0.00033 20.2 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KFH47326.1 - 9e-13 48.0 4.1 0.00033 20.9 0.7 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KFH47326.1 - 2e-09 37.0 0.0 0.00015 21.6 0.0 4.2 3 1 0 3 3 3 2 Kelch motif BTB PF00651.31 KFH47326.1 - 0.0024 18.1 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain RAG2 PF03089.14 KFH47326.1 - 0.16 10.9 0.0 0.39 9.7 0.0 1.5 1 1 0 1 1 1 0 Recombination activating protein 2 PAXIP1_C PF15364.6 KFH47327.1 - 0.073 13.4 4.5 1.2 9.5 4.5 2.0 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3837 PF12939.7 KFH47327.1 - 0.11 12.9 0.3 0.11 12.9 0.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) Conotoxin PF02950.17 KFH47327.1 - 0.57 11.2 3.3 0.54 11.3 2.1 1.6 1 1 0 1 1 1 0 Conotoxin Presenilin PF01080.17 KFH47327.1 - 7.5 5.2 6.3 7.5 5.2 6.3 1.0 1 0 0 1 1 1 0 Presenilin UreD PF01774.17 KFH47328.1 - 5.6e-76 255.2 0.0 6.6e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF2236 PF09995.9 KFH47329.1 - 5.2e-51 174.0 1.4 7.2e-51 173.6 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) EDS1_EP PF18117.1 KFH47329.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain NDT80_PhoG PF05224.12 KFH47330.1 - 1.4e-36 126.4 0.0 2.8e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AhpC-TSA PF00578.21 KFH47331.1 - 4.2e-31 107.5 0.0 5.6e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFH47331.1 - 3.5e-14 52.8 0.0 4.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFH47331.1 - 1.1e-11 44.3 0.1 2.2e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin p450 PF00067.22 KFH47332.1 - 3.8e-43 147.9 0.0 4.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3402 PF11882.8 KFH47333.1 - 2.9e-203 676.2 0.0 7.5e-203 674.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KFH47333.1 - 1.4e-95 319.8 0.0 2.1e-95 319.2 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein MSA-2c PF12238.8 KFH47333.1 - 0.089 12.8 0.2 0.089 12.8 0.2 4.2 4 0 0 4 4 4 0 Merozoite surface antigen 2c DUF3383 PF11863.8 KFH47333.1 - 0.097 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) PfkB PF00294.24 KFH47334.1 - 1.4e-16 60.7 0.0 2.1e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PIG-S PF10510.9 KFH47336.1 - 1.2e-165 552.3 0.1 1.3e-165 552.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Rhomboid PF01694.22 KFH47337.1 - 2.2e-32 112.1 8.3 2.2e-32 112.1 8.3 1.8 3 0 0 3 3 3 1 Rhomboid family Corona_S2 PF01601.16 KFH47337.1 - 4 5.8 5.4 5.8 5.3 5.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Sulfotransfer_4 PF17784.1 KFH47338.1 - 5.2e-57 193.1 0.0 6.1e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH47338.1 - 6.8e-06 26.6 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family peroxidase PF00141.23 KFH47339.1 - 2.6e-23 82.9 0.0 4.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase CBM_21 PF03370.13 KFH47339.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) FAD_binding_2 PF00890.24 KFH47340.1 - 1.6e-91 307.5 0.1 1.8e-91 307.3 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH47340.1 - 4.4e-07 30.0 0.1 1.7e-06 28.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH47340.1 - 1.9e-05 24.4 0.1 0.00031 20.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFH47340.1 - 9.7e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KFH47340.1 - 0.0001 21.6 0.1 0.00022 20.4 0.1 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KFH47340.1 - 0.00034 19.9 0.0 0.00087 18.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFH47340.1 - 0.00048 19.4 0.1 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFH47340.1 - 0.0026 17.2 0.0 0.0087 15.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH47340.1 - 0.0067 15.2 4.8 0.0085 14.8 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFH47340.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH47340.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.22 KFH47342.1 - 9.4e-41 140.0 0.0 1.1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.20 KFH47343.1 - 1e-100 336.7 0.0 1.8e-100 335.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFH47343.1 - 1.1e-57 194.7 0.0 2.2e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFH47343.1 - 3.5e-30 104.0 5.2 7.8e-30 102.9 5.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFH47343.1 - 3.7e-05 23.8 0.0 0.00017 21.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFH47343.1 - 0.34 10.6 3.4 6.3 6.4 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain adh_short_C2 PF13561.6 KFH47344.1 - 3.1e-35 121.8 0.0 5.3e-35 121.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH47344.1 - 9.5e-32 110.0 0.1 1.6e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH47344.1 - 9.1e-09 35.5 0.3 2.1e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KFH47344.1 - 0.042 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFH47344.1 - 0.058 12.4 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KFH47344.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Diphthamide_syn PF01866.17 KFH47345.1 - 8.3e-86 288.1 0.0 1e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein NAD_kinase PF01513.21 KFH47346.1 - 1.5e-67 227.8 0.0 2.2e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFH47346.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ArAE_2_N PF10337.9 KFH47347.1 - 1.2e-83 281.8 4.5 4.8e-45 154.5 4.5 2.8 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KFH47347.1 - 2.4e-57 194.4 0.0 5.7e-56 189.9 0.0 2.4 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KFH47347.1 - 2.3e-07 31.0 11.2 2.3e-07 31.0 11.2 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KFH47347.1 - 0.12 11.2 11.9 0.018 13.9 7.5 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Glyco_hydro_43 PF04616.14 KFH47348.1 - 3.4e-39 134.9 0.7 4.2e-39 134.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 KFH47348.1 - 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat p450 PF00067.22 KFH47349.1 - 1.2e-33 116.6 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HisKA PF00512.25 KFH47349.1 - 0.087 12.9 0.2 0.41 10.7 0.0 2.2 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.24 KFH47350.1 - 7.2e-99 331.7 14.7 8.2e-99 331.5 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH47350.1 - 5.1e-27 94.7 25.8 1.6e-21 76.7 4.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH47350.1 - 0.00012 20.7 0.4 0.00012 20.7 0.4 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AT_hook PF02178.19 KFH47351.1 - 1.6e-06 27.3 53.5 0.0073 16.1 1.3 5.7 5 0 0 5 5 5 5 AT hook motif MutS_V PF00488.21 KFH47352.1 - 4.5e-67 225.7 0.3 9.5e-67 224.7 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFH47352.1 - 5e-42 144.3 0.1 1.2e-41 143.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFH47352.1 - 1.6e-33 115.3 0.2 3.8e-33 114.1 0.2 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFH47352.1 - 3.1e-14 53.4 0.0 1.5e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFH47352.1 - 2e-13 50.5 0.3 5.2e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KFH47352.1 - 0.051 14.1 2.2 0.082 13.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KFH47352.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFH47352.1 - 0.088 12.6 1.4 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFH47352.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SPT6_acidic PF14632.6 KFH47352.1 - 1.2 9.8 5.2 1.2 9.8 0.6 2.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Shugoshin_C PF07557.11 KFH47352.1 - 4.5 7.1 11.8 0.33 10.8 1.3 2.7 2 0 0 2 2 2 0 Shugoshin C terminus HET PF06985.11 KFH47353.1 - 1.1e-19 71.3 0.0 6.7e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1350 PF07082.11 KFH47353.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) zf-C2H2 PF00096.26 KFH47354.1 - 3.6e-05 24.0 1.4 8e-05 22.9 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH47354.1 - 0.024 15.5 0.8 0.045 14.6 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-CGNR PF11706.8 KFH47354.1 - 0.026 14.4 0.2 0.045 13.6 0.2 1.3 1 0 0 1 1 1 0 CGNR zinc finger FOXP-CC PF16159.5 KFH47354.1 - 0.063 13.9 0.1 0.081 13.6 0.1 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 KFH47354.1 - 0.12 12.4 0.9 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.6 KFH47354.1 - 1.1 9.8 4.9 0.43 11.1 1.2 2.0 2 0 0 2 2 2 0 Zinc-finger double domain HA2 PF04408.23 KFH47355.1 - 2.5e-18 66.3 0.7 3.9e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFH47355.1 - 2.1e-16 60.3 0.0 1.2e-15 57.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFH47355.1 - 4.5e-16 59.0 0.0 1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFH47355.1 - 2.4e-10 40.5 0.1 1.1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 KFH47355.1 - 4.2e-07 30.3 0.2 9e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 RWD domain ATPase PF06745.13 KFH47355.1 - 0.00089 18.7 0.2 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 1 KaiC IHABP4_N PF16174.5 KFH47355.1 - 0.0013 19.4 1.0 0.0013 19.4 1.0 2.4 3 0 0 3 3 2 1 Intracellular hyaluronan-binding protein 4 N-terminal AAA_22 PF13401.6 KFH47355.1 - 0.0027 18.0 1.1 0.019 15.2 1.1 2.3 1 1 0 1 1 1 1 AAA domain dsRBD2 PF17842.1 KFH47355.1 - 0.0054 17.0 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 AAA_29 PF13555.6 KFH47355.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DND1_DSRM PF14709.7 KFH47355.1 - 0.01 16.1 0.1 0.034 14.4 0.1 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_25 PF13481.6 KFH47355.1 - 0.015 14.9 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFH47355.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFH47355.1 - 0.034 14.7 0.9 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain UBA PF00627.31 KFH47355.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.1 1 0 0 1 1 1 0 UBA/TS-N domain Bac_rhodopsin PF01036.18 KFH47357.1 - 2.3e-46 158.2 19.8 3.1e-46 157.7 19.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 KFH47357.1 - 0.0015 17.9 11.4 0.0029 17.0 11.4 1.6 1 1 0 1 1 1 1 Heliorhodopsin DUF4131 PF13567.6 KFH47357.1 - 1 9.0 10.7 0.45 10.1 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MerC PF03203.14 KFH47357.1 - 2.1 8.8 16.0 1.9 8.9 8.3 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DNA_pol_E_B PF04042.16 KFH47358.1 - 1.3e-49 168.5 0.0 1.8e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KFH47358.1 - 3e-39 134.1 0.0 4.9e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain p450 PF00067.22 KFH47359.1 - 1.5e-47 162.4 0.0 2.1e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 POT1PC PF16686.5 KFH47360.1 - 2.2e-41 141.3 0.0 3.7e-40 137.3 0.0 2.6 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFH47360.1 - 8.2e-18 64.6 0.3 2.8e-17 62.9 0.0 2.0 2 1 1 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 BTB PF00651.31 KFH47361.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 KFH47362.1 - 9.9e-30 103.6 29.6 9.9e-30 103.6 29.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 KFH47362.1 - 0.2 11.8 2.9 7 6.9 0.0 3.4 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.24 KFH47364.1 - 1.3e-77 261.6 12.6 8.3e-48 163.4 0.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFH47364.1 - 1.2e-29 103.4 14.7 2.1e-17 63.1 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH47364.1 - 0.0079 14.7 1.1 0.016 13.7 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 KFH47364.1 - 1.8 8.8 12.0 6.4 7.0 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF3384 PF11864.8 KFH47365.1 - 7.8e-146 486.7 0.0 7.8e-146 486.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KFH47365.1 - 9.7e-55 185.0 0.0 1.6e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KFH47365.1 - 3.3e-36 125.1 0.7 1.5e-30 106.5 0.0 4.2 4 0 0 4 4 4 2 Tuberin TFIIA PF03153.13 KFH47365.1 - 3.1 7.7 11.7 5.3 6.9 10.7 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 KFH47365.1 - 6.6 5.5 13.7 12 4.7 13.7 1.3 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 KFH47365.1 - 9 5.8 9.5 17 4.9 9.5 1.3 1 0 0 1 1 1 0 Spt20 family Aldo_ket_red PF00248.21 KFH47366.1 - 5e-47 160.5 0.0 2.9e-45 154.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 KFH47367.1 - 8.9e-07 29.0 0.2 2.6e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH47367.1 - 1e-05 25.7 0.5 2.1e-05 24.6 0.3 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KFH47367.1 - 0.04 14.0 0.0 0.082 13.0 0.0 1.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glyco_hydro_28 PF00295.17 KFH47369.1 - 7.1e-11 41.7 0.7 3.8e-10 39.3 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KFH47369.1 - 5e-08 33.0 3.6 2.1e-07 31.0 1.8 2.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein Beta_helix PF13229.6 KFH47369.1 - 0.14 12.0 6.1 0.18 11.6 0.7 2.8 1 1 1 2 2 2 0 Right handed beta helix region ELFV_dehydrog PF00208.21 KFH47370.1 - 2.5e-76 256.6 1.2 2e-75 253.6 1.2 1.9 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFH47370.1 - 1.4e-50 170.5 0.0 2.3e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CENP-I PF07778.11 KFH47371.1 - 2.3e-40 138.8 0.0 4.1e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Mis6 Las1 PF04031.13 KFH47373.1 - 9.3e-62 207.7 0.0 1.7e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KFH47373.1 - 4.1e-21 75.3 0.2 9.6e-21 74.1 0.2 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFH47373.1 - 1.2e-06 28.7 0.4 2.8e-05 24.2 0.1 2.3 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily DUF1236 PF06823.12 KFH47373.1 - 0.1 12.5 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) GMC_oxred_N PF00732.19 KFH47374.1 - 1.4e-55 188.7 0.0 2.4e-55 188.0 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH47374.1 - 1.8e-31 109.6 0.0 7.2e-31 107.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFH47374.1 - 0.0012 18.0 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH47374.1 - 0.0021 18.2 0.0 0.0079 16.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH47374.1 - 0.0023 17.2 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH47374.1 - 0.051 13.2 0.1 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFH47374.1 - 0.18 11.0 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CM_1 PF07736.11 KFH47376.1 - 0.084 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Chorismate mutase type I Suf PF05843.14 KFH47376.1 - 2.5 8.0 6.8 3.2 7.6 6.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 KFH47376.1 - 2.6 7.9 11.4 3.4 7.6 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IF4E PF01652.18 KFH47377.1 - 6.5e-34 117.0 0.0 8.5e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.22 KFH47378.1 - 3.1e-65 220.7 0.0 5e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 EBP PF05241.12 KFH47381.1 - 1.6e-70 236.1 10.6 1.9e-70 235.9 10.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein CRM1_repeat_3 PF18787.1 KFH47381.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 GLEYA PF10528.9 KFH47382.1 - 7.3e-25 87.2 0.2 1.3e-24 86.4 0.2 1.4 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KFH47382.1 - 2.5e-05 24.1 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Squash PF00299.18 KFH47382.1 - 4.2 7.5 225.5 0.083 12.9 1.9 22.0 23 0 0 23 23 23 0 Squash family serine protease inhibitor PAP2 PF01569.21 KFH47383.1 - 2.3e-12 46.8 5.4 4e-12 46.1 4.1 2.0 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KFH47383.1 - 3.1e-05 23.4 2.5 3.1e-05 23.4 2.5 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 KFH47383.1 - 0.0076 16.4 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 1 Divergent PAP2 family Glyco_trans_4_4 PF13579.6 KFH47383.1 - 0.2 12.1 11.0 0.022 15.2 6.1 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Phage_holin_8 PF16931.5 KFH47383.1 - 0.25 11.3 4.2 0.07 13.1 1.2 1.6 2 0 0 2 2 2 0 Putative phage holin DNA_pol_B PF00136.21 KFH47384.1 - 1e-143 479.4 0.6 1.5e-143 478.9 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFH47384.1 - 4.2e-80 269.4 0.3 8.4e-80 268.4 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFH47384.1 - 1.3e-17 64.0 6.1 3.1e-17 62.8 6.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KFH47384.1 - 0.0067 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFH47384.1 - 0.022 14.8 0.2 0.18 11.8 0.2 2.5 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_2 PF03175.13 KFH47384.1 - 0.031 13.2 0.1 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Sugar_tr PF00083.24 KFH47385.1 - 1.3e-85 287.9 16.7 1.5e-85 287.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH47385.1 - 5.4e-19 68.3 40.6 1.3e-13 50.6 17.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFH47385.1 - 0.4 8.9 5.4 0.51 8.5 2.8 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4407 PF14362.6 KFH47387.1 - 0.4 10.0 4.2 0.75 9.1 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KFH47387.1 - 3.6 8.1 14.7 11 6.5 14.7 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Presenilin PF01080.17 KFH47387.1 - 5.6 5.6 4.6 7.9 5.1 4.6 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KFH47388.1 - 5.2e-34 117.8 0.0 5.2e-34 117.8 0.0 3.2 3 1 0 3 3 3 1 RNA polymerase III RPC4 Med3 PF11593.8 KFH47388.1 - 0.31 10.2 3.8 0.5 9.5 3.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4603 PF15376.6 KFH47388.1 - 2.8 5.2 7.0 3.9 4.8 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF3712 PF12505.8 KFH47389.1 - 3.6e-26 91.9 0.2 6.7e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Orai-1 PF07856.12 KFH47389.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF2207 PF09972.9 KFH47389.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatD PF13584.6 KFH47389.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Mit_KHE1 PF10173.9 KFH47389.1 - 0.23 11.5 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related NmrA PF05368.13 KFH47390.1 - 1.3e-62 211.5 0.3 1.5e-62 211.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH47390.1 - 1.3e-19 70.8 0.1 1.7e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFH47390.1 - 0.0023 17.0 0.1 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SQHop_cyclase_C PF13243.6 KFH47392.1 - 0.0015 17.7 0.2 0.076 12.1 0.0 3.0 3 0 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KFH47392.1 - 0.0094 15.7 0.4 0.09 12.5 0.1 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat DUF2011 PF09428.10 KFH47393.1 - 1.9e-22 79.3 1.2 4.6e-22 78.1 0.0 2.2 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) MARVEL PF01284.23 KFH47394.1 - 2.3e-14 53.6 18.3 3e-14 53.3 18.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.28 KFH47395.1 - 5e-72 242.8 0.0 6.6e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH47395.1 - 1.1e-07 32.7 1.3 6.1e-07 30.3 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain polyprenyl_synt PF00348.17 KFH47396.1 - 9.8e-66 221.4 0.0 1.2e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MARVEL PF01284.23 KFH47397.1 - 0.0016 18.5 18.1 0.0034 17.4 18.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 KFH47397.1 - 0.041 13.8 12.0 0.16 11.9 6.2 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Adeno_E3B PF03376.14 KFH47397.1 - 0.19 12.0 5.8 0.36 11.1 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3B protein ABC2_membrane_5 PF13346.6 KFH47397.1 - 0.22 11.0 9.0 0.32 10.5 4.8 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Sigma_reg_N PF13800.6 KFH47397.1 - 0.28 11.5 1.9 2.4 8.5 0.1 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 7tm_7 PF08395.12 KFH47397.1 - 0.92 8.7 7.9 0.19 10.9 3.8 1.7 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF4233 PF14017.6 KFH47397.1 - 1.2 9.5 9.9 0.55 10.6 6.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) PhoLip_ATPase_C PF16212.5 KFH47397.1 - 2 8.1 10.3 6.1 6.5 10.5 1.6 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal MFS_1 PF07690.16 KFH47398.1 - 3.7e-23 82.0 32.6 2.2e-22 79.5 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_Tnp_1_2 PF13586.6 KFH47398.1 - 0.25 11.7 0.4 0.51 10.7 0.4 1.4 1 0 0 1 1 1 0 Transposase DDE domain Acyl-CoA_dh_1 PF00441.24 KFH47399.1 - 3.7e-29 101.9 0.7 5.2e-29 101.4 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH47399.1 - 9.6e-21 73.8 0.1 1.6e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFH47399.1 - 5.2e-20 72.2 0.0 1.3e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFH47399.1 - 0.0066 16.7 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 4HBT_2 PF13279.6 KFH47400.1 - 0.00049 20.6 0.0 0.00074 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily CENP-S PF15630.6 KFH47401.1 - 3.5e-35 120.2 0.0 4.5e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFH47401.1 - 2.6e-07 30.7 0.0 3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KFH47401.1 - 0.0021 18.0 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KFH47401.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2773 PF10971.8 KFH47401.1 - 0.081 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) FAD_binding_3 PF01494.19 KFH47402.1 - 2.3e-11 43.6 0.2 9.8e-11 41.5 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFH47402.1 - 0.00082 19.0 0.2 0.08 12.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH47402.1 - 0.026 13.7 0.2 0.46 9.7 0.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.23 KFH47403.1 - 2.7e-113 378.3 0.0 4.5e-113 377.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFH47403.1 - 1.8e-26 92.9 0.3 4.9e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 KFH47403.1 - 0.00058 18.8 10.4 0.0012 17.8 10.2 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF3512 PF12024.8 KFH47403.1 - 0.016 14.7 0.1 0.016 14.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) Exonuc_VII_L PF02601.15 KFH47403.1 - 0.078 12.5 8.7 0.013 15.1 4.5 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tau95 PF09734.9 KFH47403.1 - 0.16 12.7 2.8 0.47 11.3 2.8 1.7 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF87 PF01935.17 KFH47403.1 - 0.77 9.8 0.0 0.77 9.8 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2018 PF09442.10 KFH47403.1 - 1.3 10.0 8.9 2.2 9.3 3.8 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF2018) DUF5094 PF17015.5 KFH47403.1 - 1.3 9.1 6.7 3.3 7.8 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Noggin PF05806.12 KFH47403.1 - 1.4 8.8 4.9 7 6.5 0.4 3.0 3 0 0 3 3 3 0 Noggin FapA PF03961.13 KFH47403.1 - 1.4 7.4 5.9 2.1 6.8 5.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3037 PF11236.8 KFH47403.1 - 1.5 9.3 5.2 4.2 7.8 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF2721 PF11026.8 KFH47403.1 - 4.5 7.2 4.8 12 5.8 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) CoA_transf_3 PF02515.17 KFH47404.1 - 1.6e-71 241.4 0.0 1.9e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF2484 PF10658.9 KFH47404.1 - 0.094 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) MARVEL PF01284.23 KFH47405.1 - 0.00086 19.4 13.5 0.00086 19.4 13.5 1.6 1 1 0 1 1 1 1 Membrane-associating domain PLDc_N PF13396.6 KFH47405.1 - 0.13 12.2 3.6 0.38 10.7 0.3 2.9 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal SelK_SelG PF10961.8 KFH47405.1 - 0.15 12.7 0.4 0.48 11.1 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF3493 PF11998.8 KFH47405.1 - 0.31 11.2 7.7 0.88 9.8 0.1 2.6 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF4293 PF14126.6 KFH47405.1 - 1.3 9.3 5.7 0.76 10.0 2.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2568 PF10823.8 KFH47405.1 - 1.3 9.3 8.4 0.41 10.9 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) 7TMR-DISM_7TM PF07695.11 KFH47405.1 - 7.2 6.4 16.2 5 7.0 11.7 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF3687 PF12459.8 KFH47406.1 - 0.43 10.1 2.9 0.61 9.6 2.9 1.2 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Abhydrolase_1 PF00561.20 KFH47407.1 - 0.0019 17.9 0.0 0.1 12.2 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH47407.1 - 0.0024 17.2 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFH47407.1 - 0.21 11.0 0.0 0.56 9.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family zf-C2HE PF16278.5 KFH47408.1 - 6.4e-17 61.8 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KFH47408.1 - 3.2e-15 56.7 0.6 6.7e-15 55.6 0.6 1.5 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFH47408.1 - 3.5e-14 53.2 2.7 9.3e-08 32.5 0.2 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding DUF3336 PF11815.8 KFH47409.1 - 2.2e-34 118.1 0.2 4.1e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFH47409.1 - 2e-19 70.6 0.1 5.8e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Zn_clus PF00172.18 KFH47411.1 - 1.4e-06 28.4 10.7 1.4e-06 28.4 10.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm PF00514.23 KFH47412.1 - 4.5e-93 302.8 15.9 2.7e-13 49.4 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFH47412.1 - 2e-27 95.4 2.7 2.8e-27 95.0 1.2 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KFH47412.1 - 1.5e-24 85.3 3.3 3.4e-24 84.1 2.8 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFH47412.1 - 5.6e-22 77.8 9.1 1.3e-09 38.4 0.1 6.2 6 1 1 7 7 6 4 HEAT-like repeat HEAT PF02985.22 KFH47412.1 - 2.8e-19 67.5 0.6 3.5e-06 26.8 0.0 6.8 7 0 0 7 7 6 4 HEAT repeat HEAT_2 PF13646.6 KFH47412.1 - 3.1e-19 69.1 0.1 4.5e-09 36.6 0.0 5.0 1 1 1 4 4 4 3 HEAT repeats Arm_2 PF04826.13 KFH47412.1 - 8.4e-08 32.0 0.0 0.21 11.0 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KFH47412.1 - 7.4e-05 21.5 0.0 0.0012 17.5 0.0 2.5 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFH47412.1 - 0.00012 22.2 0.0 5 7.3 0.0 4.2 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 KFH47412.1 - 0.0012 19.1 2.5 0.77 10.0 0.1 4.7 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KFH47412.1 - 0.0026 18.3 0.2 2 9.3 0.0 3.7 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KFH47412.1 - 0.0046 17.0 0.0 4.5 7.3 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 KFH47412.1 - 0.064 13.3 0.0 18 5.4 0.0 3.0 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Glycos_trans_3N PF02885.17 KFH47412.1 - 0.14 12.0 0.0 8.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NUSAP PF16006.5 KFH47412.1 - 6.8 6.4 6.4 9.6 5.9 6.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein HC2 PF07382.11 KFH47413.1 - 0.0032 17.6 31.3 0.0099 16.0 31.3 1.8 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 SNF PF00209.18 KFH47414.1 - 1.6e-91 307.6 35.9 3.4e-89 299.9 35.9 2.1 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family TMEM234 PF10639.9 KFH47414.1 - 0.69 10.0 8.1 4.8 7.3 0.4 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 6PGD PF00393.19 KFH47415.1 - 7.4e-125 416.1 0.0 9e-125 415.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFH47415.1 - 4e-49 166.8 0.0 5.9e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFH47415.1 - 0.047 13.9 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DNA_pol3_beta PF00712.19 KFH47415.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain STAG PF08514.11 KFH47416.1 - 8e-35 119.2 0.4 6e-34 116.4 0.4 2.6 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KFH47416.1 - 3.6e-05 24.1 0.6 0.00054 20.3 0.0 3.2 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KFH47416.1 - 0.095 13.0 0.1 56 4.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Oxidored_FMN PF00724.20 KFH47417.1 - 0.0042 16.4 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GFO_IDH_MocA PF01408.22 KFH47418.1 - 9.7e-15 55.5 0.0 1.5e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFH47418.1 - 3.9e-06 27.5 0.0 7.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Elongin_A PF06881.11 KFH47419.1 - 0.049 14.2 0.0 3.6 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PBP1_TM PF14812.6 KFH47419.1 - 0.63 10.4 8.9 1.4 9.4 0.3 3.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 KFH47420.1 - 5.4e-31 107.8 47.1 5.4e-31 107.8 47.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transglut_core PF01841.19 KFH47420.1 - 0.06 13.8 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily Cm_res_leader PF08077.11 KFH47420.1 - 3.8 7.9 5.0 4.1 7.8 0.1 3.8 4 0 0 4 4 4 0 Chloramphenicol resistance gene leader peptide ABC2_membrane PF01061.24 KFH47421.1 - 3.3e-81 271.7 55.1 6.8e-44 149.8 22.2 4.3 4 0 0 4 4 4 3 ABC-2 type transporter PDR_CDR PF06422.12 KFH47421.1 - 2.7e-36 123.3 2.1 3.4e-29 100.6 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.27 KFH47421.1 - 3.2e-33 115.1 0.0 5e-15 56.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KFH47421.1 - 3e-10 40.6 0.0 9.1e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFH47421.1 - 4.3e-08 33.7 0.4 0.00013 22.5 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KFH47421.1 - 3.6e-05 23.1 15.9 3.6e-05 23.1 15.9 3.9 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFH47421.1 - 0.00011 22.2 0.2 0.43 10.3 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFH47421.1 - 0.00016 21.3 0.1 0.0039 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFH47421.1 - 0.00028 20.6 0.5 0.037 13.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH47421.1 - 0.0003 20.7 0.0 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFH47421.1 - 0.001 19.3 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFH47421.1 - 0.002 18.7 0.0 0.38 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH47421.1 - 0.0042 16.8 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFH47421.1 - 0.012 15.6 0.2 3.3 7.6 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KFH47421.1 - 0.013 15.9 0.0 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFH47421.1 - 0.023 14.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFH47421.1 - 0.032 14.7 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KFH47421.1 - 0.051 13.2 0.1 0.9 9.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KFH47421.1 - 0.052 13.3 0.1 7.7 6.2 0.0 2.7 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 KFH47421.1 - 0.063 13.8 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.10 KFH47422.1 - 0.0019 17.6 4.9 0.0041 16.5 4.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KFH47422.1 - 0.0031 17.3 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 KFH47422.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Methyltransf_23 PF13489.6 KFH47423.1 - 8e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47423.1 - 1.1e-09 38.8 0.0 5.5e-08 33.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47423.1 - 6.3e-09 36.4 0.0 9.4e-08 32.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47423.1 - 1.2e-06 29.2 0.0 1.5e-05 25.7 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH47423.1 - 0.0019 17.5 0.0 0.0057 16.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFH47423.1 - 0.0032 17.3 0.0 0.04 13.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain GFO_IDH_MocA_C PF02894.17 KFH47424.1 - 7.8e-18 64.6 0.1 1.7e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KFH47424.1 - 7.4e-17 62.3 0.0 2.7e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Mannosidase_ig PF17786.1 KFH47425.1 - 5e-14 52.7 2.0 5e-14 52.7 2.0 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFH47425.1 - 2.5e-10 41.0 1.4 2.9e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFH47425.1 - 0.00097 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFH47425.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KFH47425.1 - 0.086 12.6 0.2 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Ig-fold domain AhpC-TSA PF00578.21 KFH47426.1 - 3.1e-08 33.6 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFH47426.1 - 6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFH47426.1 - 0.055 13.2 0.0 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Sacchrp_dh_C PF16653.5 KFH47427.1 - 4.5e-83 279.4 0.0 2.7e-82 276.8 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KFH47427.1 - 1.1e-22 80.7 0.2 1.7e-22 80.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFH47427.1 - 2.8e-05 24.1 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KFH47427.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UbiA PF01040.18 KFH47428.1 - 4.6e-61 206.3 15.5 4.6e-61 206.3 15.5 1.7 1 1 1 2 2 2 1 UbiA prenyltransferase family FAD_oxidored PF12831.7 KFH47429.1 - 2.7e-114 382.9 0.0 3.5e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH47429.1 - 0.24 10.6 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.13 KFH47430.1 - 1.2e-07 31.9 0.1 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH47430.1 - 1.7e-06 28.8 5.0 2.4e-06 28.3 5.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH47430.1 - 0.0016 17.8 0.1 0.0033 16.7 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFH47430.1 - 0.0062 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KFH47430.1 - 0.011 15.4 0.0 0.038 13.6 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KFH47430.1 - 0.031 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3089 PF11288.8 KFH47430.1 - 0.048 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Acetyltransf_1 PF00583.25 KFH47431.1 - 3.9e-06 27.1 0.0 2.1e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH47431.1 - 7.2e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH47431.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH47431.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 KFH47431.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KFH47431.1 - 0.1 12.6 0.1 0.94 9.5 0.0 2.5 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase Fungal_trans PF04082.18 KFH47432.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain EP400_N PF15790.5 KFH47432.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Alpha-L-AF_C PF06964.12 KFH47433.1 - 1.6e-26 93.5 0.0 2.5e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain EF-hand_9 PF14658.6 KFH47434.1 - 0.00025 21.3 0.0 0.017 15.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFH47434.1 - 0.00097 19.5 0.0 0.098 13.1 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFH47434.1 - 0.013 15.4 0.0 6.3 7.0 0.0 4.0 4 1 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 KFH47434.1 - 0.096 12.3 3.6 3.9 7.2 0.0 4.1 5 0 0 5 5 5 0 EF hand ABC_tran PF00005.27 KFH47436.1 - 7.5e-15 55.7 0.0 6e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFH47436.1 - 1.4e-11 44.8 0.2 0.00015 21.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KFH47436.1 - 0.00066 17.4 0.1 0.00087 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KFH47436.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 KFH47436.1 - 0.0035 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SMC_N PF02463.19 KFH47436.1 - 0.0036 16.8 0.0 2.4 7.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFH47436.1 - 0.0054 17.3 0.0 0.0078 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFH47436.1 - 0.0074 16.0 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFH47436.1 - 0.028 14.0 0.1 0.049 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFH47436.1 - 0.033 14.4 1.2 0.033 14.4 0.1 1.5 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KFH47436.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KFH47436.1 - 0.054 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFH47436.1 - 0.06 13.6 0.3 0.16 12.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFH47436.1 - 0.082 13.3 1.0 0.24 11.7 1.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KFH47436.1 - 0.086 12.3 0.4 0.23 10.9 0.4 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 KFH47436.1 - 0.086 13.3 0.2 0.3 11.5 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KFH47436.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFH47436.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KFH47436.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFH47436.1 - 0.18 11.7 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain SIR2 PF02146.17 KFH47438.1 - 1.1e-55 188.3 0.0 1.7e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family CDC45 PF02724.14 KFH47438.1 - 8.6 4.5 15.2 0.019 13.3 1.8 2.0 1 1 1 2 2 2 0 CDC45-like protein DAHP_synth_1 PF00793.20 KFH47439.1 - 5.5e-105 350.2 0.1 6.8e-105 349.9 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family YIEGIA PF14045.6 KFH47439.1 - 0.038 12.8 0.2 0.061 12.2 0.2 1.2 1 0 0 1 1 1 0 YIEGIA protein Ribosomal_L7Ae PF01248.26 KFH47440.1 - 2.1e-23 81.9 0.0 2.4e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 2-Hacid_dh_C PF02826.19 KFH47441.1 - 1e-54 184.6 0.1 2e-54 183.7 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH47441.1 - 7.4e-37 126.0 0.2 1.1e-36 125.5 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KFH47441.1 - 4.3e-05 23.2 1.3 7.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KFH47441.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain adh_short PF00106.25 KFH47442.1 - 8.3e-45 152.6 0.5 1.1e-44 152.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH47442.1 - 2.4e-34 118.9 0.4 2.7e-34 118.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH47442.1 - 2.6e-11 43.8 0.3 4.4e-11 43.0 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFH47442.1 - 1.9e-06 27.9 0.7 6.4e-06 26.2 0.6 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH47442.1 - 9.4e-05 22.0 0.1 0.00015 21.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH47442.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KFH47442.1 - 0.08 13.2 0.1 0.27 11.5 0.0 1.9 3 0 0 3 3 3 0 TrkA-N domain TF_Zn_Ribbon PF08271.12 KFH47444.1 - 0.051 13.1 2.7 3.5 7.2 0.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE_2 PF02318.16 KFH47444.1 - 0.47 10.7 6.4 0.21 11.8 3.9 1.6 1 1 1 2 2 2 0 FYVE-type zinc finger His_biosynth PF00977.21 KFH47445.1 - 3.7e-50 170.5 0.2 1.6e-49 168.5 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KFH47445.1 - 7.3e-19 68.3 0.0 1.2e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KFH47445.1 - 5.2e-08 32.9 0.0 9.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFH47445.1 - 6.4e-06 25.9 0.0 2.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KFH47445.1 - 0.026 14.3 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_C26 PF07722.13 KFH47445.1 - 0.048 13.4 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.17 KFH47445.1 - 0.22 10.6 0.0 1.2 8.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) HEAT PF02985.22 KFH47447.1 - 0.0011 19.1 0.1 0.012 15.8 0.1 3.0 1 0 0 1 1 1 1 HEAT repeat Arm PF00514.23 KFH47447.1 - 0.018 15.1 0.5 0.26 11.4 0.3 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFH47447.1 - 0.066 13.7 0.2 0.64 10.6 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 KFH47447.1 - 0.13 12.7 4.9 0.19 12.2 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats NUDIX PF00293.28 KFH47448.1 - 3.3e-15 56.3 2.2 8.4e-15 55.0 2.2 1.6 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFH47448.1 - 0.0029 17.6 0.2 0.014 15.3 0.2 2.0 1 1 0 1 1 1 1 NUDIX domain Lactonase PF10282.9 KFH47449.1 - 1.5e-14 54.0 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller F-box-like PF12937.7 KFH47451.1 - 0.0038 17.1 0.2 0.011 15.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like BPL_N PF09825.9 KFH47452.1 - 1.2e-140 469.0 0.0 1.5e-140 468.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KFH47452.1 - 4.5e-17 62.2 0.1 1.5e-16 60.5 0.1 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Sugar_tr PF00083.24 KFH47453.1 - 5.1e-77 259.6 19.7 5.9e-77 259.4 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH47453.1 - 8.5e-17 61.1 26.8 8.5e-17 61.1 26.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2852 PF11014.8 KFH47453.1 - 0.039 14.1 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Terpene_synth_C PF03936.16 KFH47455.1 - 0.044 13.1 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Erythro-docking PF09277.11 KFH47455.1 - 0.29 11.1 1.7 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 Erythronolide synthase, docking TFIIA PF03153.13 KFH47457.1 - 0.00017 21.7 9.6 0.00019 21.6 9.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PRC2_HTH_1 PF18118.1 KFH47457.1 - 0.056 14.2 2.5 0.12 13.2 2.5 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain EPL1 PF10513.9 KFH47457.1 - 0.078 13.4 4.0 0.13 12.7 4.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.9 KFH47457.1 - 0.21 9.8 11.7 0.27 9.5 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GOLD_2 PF13897.6 KFH47457.1 - 0.22 12.0 1.1 0.4 11.2 1.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Pex14_N PF04695.13 KFH47457.1 - 0.3 11.7 16.9 0.053 14.2 12.4 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 KFH47457.1 - 0.32 10.5 8.9 0.46 10.0 8.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC53 PF10152.9 KFH47457.1 - 0.75 10.2 7.0 1.5 9.2 7.0 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 KFH47457.1 - 1.2 9.1 4.8 1.8 8.5 4.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 KFH47457.1 - 1.4 7.7 9.2 1.8 7.3 9.2 1.1 1 0 0 1 1 1 0 Presenilin Cyclin PF08613.11 KFH47457.1 - 1.7 9.0 4.5 3.2 8.1 4.5 1.4 1 0 0 1 1 1 0 Cyclin Spt20 PF12090.8 KFH47457.1 - 2.7 7.5 21.6 4.4 6.9 21.6 1.3 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 KFH47457.1 - 2.9 8.0 5.9 5.6 7.1 5.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LRRC37AB_C PF14914.6 KFH47457.1 - 3.1 7.7 6.1 5.1 7.0 6.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Neur_chan_memb PF02932.16 KFH47457.1 - 4.4 7.3 4.7 6.5 6.7 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 KFH47457.1 - 5 6.9 10.6 8.7 6.1 10.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus Kei1 PF08552.11 KFH47457.1 - 6.1 6.7 6.6 12 5.8 6.6 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Suf PF05843.14 KFH47457.1 - 8 6.3 11.2 15 5.5 11.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HSP70 PF00012.20 KFH47458.1 - 0.31 9.2 4.3 0.36 9.0 4.3 1.1 1 0 0 1 1 1 0 Hsp70 protein Phage_Gp23 PF10669.9 KFH47458.1 - 5.7 7.3 10.3 1.3 9.3 5.8 2.1 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Glyco_hydro_61 PF03443.14 KFH47459.1 - 6.7e-58 196.0 0.3 8.4e-58 195.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AMP-binding PF00501.28 KFH47460.1 - 1.7e-81 274.0 0.0 2.7e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFH47460.1 - 1.3e-59 202.1 0.0 6.8e-31 107.4 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KFH47460.1 - 7.5e-08 32.6 0.0 3.4e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH47460.1 - 0.00034 21.5 0.0 0.0017 19.3 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FSA_C PF10479.9 KFH47460.1 - 0.15 10.2 0.2 0.23 9.6 0.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus P5CR_dimer PF14748.6 KFH47461.1 - 5.8e-28 97.2 3.0 1e-27 96.4 3.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFH47461.1 - 2.6e-11 43.9 0.0 6.4e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3438 PF11920.8 KFH47461.1 - 0.1 11.8 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) LRR_8 PF13855.6 KFH47462.1 - 1.6e-11 43.8 4.7 1.6e-07 31.0 0.5 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFH47462.1 - 5.9e-08 32.9 2.5 9.8e-06 25.8 1.8 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH47462.1 - 0.001 19.3 2.5 1.9 9.3 1.6 4.1 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KFH47462.1 - 0.14 12.3 2.0 8.2 6.8 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeat Amidase PF01425.21 KFH47463.1 - 1.4e-112 377.0 0.1 2e-112 376.5 0.1 1.2 1 0 0 1 1 1 1 Amidase Methyltransf_24 PF13578.6 KFH47464.1 - 5.5e-10 40.2 0.0 9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KFH47464.1 - 0.00069 18.8 0.0 0.029 13.5 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase Ribosomal_S27e PF01667.17 KFH47466.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KFH47466.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KFH47466.1 - 0.67 10.0 7.1 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Gpr1_Fun34_YaaH PF01184.19 KFH47467.1 - 6.4e-34 117.4 21.7 7.9e-34 117.1 21.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Dicty_CAR PF05462.11 KFH47467.1 - 0.035 13.2 5.9 0.047 12.8 5.9 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DUF4191 PF13829.6 KFH47468.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pkinase PF00069.25 KFH47469.1 - 1.3e-71 241.0 0.0 1.9e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47469.1 - 4.1e-46 157.4 0.0 7.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFH47469.1 - 2.2e-19 69.6 0.0 6.7e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KFH47469.1 - 1.8e-07 30.3 0.0 3.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH47469.1 - 4.9e-07 29.3 0.0 8.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFH47469.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFH47469.1 - 0.028 14.3 0.6 0.1 12.5 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFH47469.1 - 0.029 13.7 0.0 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 KFH47469.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Seadorna_VP7 PF07387.11 KFH47469.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FHA PF00498.26 KFH47470.1 - 7.8e-18 64.6 0.1 2.1e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFH47470.1 - 4.2e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KFH47470.1 - 0.003 17.1 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 YhfZ C-terminal domain DUF2175 PF09943.9 KFH47470.1 - 0.67 10.3 5.9 0.12 12.6 1.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GAS PF13851.6 KFH47470.1 - 0.89 8.9 12.8 0.021 14.2 2.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KFH47470.1 - 1.7 9.3 11.8 56 4.4 10.1 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 KFH47470.1 - 2.4 8.3 7.6 38 4.5 6.5 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 KFH47470.1 - 6.2 7.1 10.5 3.2 8.0 1.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA PI3K_P85_iSH2 PF16454.5 KFH47470.1 - 6.4 6.3 11.2 80 2.8 11.3 2.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1297 PF06973.12 KFH47471.1 - 0.057 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) SIP1 PF04938.12 KFH47472.1 - 1.3e-06 28.3 1.5 0.00034 20.4 0.0 3.2 3 1 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) FAD_binding_3 PF01494.19 KFH47473.1 - 4.8e-71 239.8 0.0 6.5e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFH47473.1 - 1.3e-10 41.4 1.8 1.2e-07 31.6 0.5 2.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFH47473.1 - 0.00077 20.0 0.0 0.14 12.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH47473.1 - 0.0017 17.7 0.3 0.47 9.6 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH47473.1 - 0.016 15.4 0.2 0.3 11.4 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH47473.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KFH47473.1 - 0.12 11.7 0.0 1.6 8.0 0.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 KFH47474.1 - 6.1e-18 65.0 0.0 4.7e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH47474.1 - 1e-08 35.0 0.0 1.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH47474.1 - 5.3e-05 23.2 0.0 7.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain EBV-NA3 PF05009.12 KFH47475.1 - 1.2 8.6 4.4 12 5.3 3.3 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.12 KFH47475.1 - 2.1 7.6 4.7 3.3 6.9 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein SSP160 PF06933.11 KFH47476.1 - 6.3 4.9 14.5 9.2 4.3 14.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PRP1_N PF06424.12 KFH47477.1 - 5.4e-51 172.9 9.1 1.3e-50 171.6 9.1 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFH47477.1 - 1.8e-30 103.0 33.8 8e-05 23.1 0.2 14.7 6 3 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 KFH47477.1 - 1.9e-28 98.8 15.8 5.7e-07 30.0 0.1 10.5 6 3 3 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFH47477.1 - 3.8e-13 49.8 13.9 0.0016 19.1 0.0 8.6 6 2 4 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFH47477.1 - 1.2e-11 43.8 11.9 0.79 10.0 0.0 10.7 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFH47477.1 - 3.4e-11 42.7 7.4 3.6 8.2 0.0 10.8 9 2 2 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH47477.1 - 3.4e-10 39.3 5.3 0.016 15.3 0.0 9.0 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH47477.1 - 1.2e-07 31.8 6.7 0.0024 18.0 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFH47477.1 - 1.1e-06 28.2 2.7 0.34 10.6 0.0 6.7 6 2 2 8 8 8 2 TPR repeat NARP1 PF12569.8 KFH47477.1 - 8.3e-06 25.0 7.3 0.88 8.4 0.0 6.0 3 1 3 7 7 7 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KFH47477.1 - 1e-05 25.1 0.0 0.53 10.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH47477.1 - 1.3e-05 25.3 0.3 0.072 13.3 0.0 4.6 3 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFH47477.1 - 2.6e-05 24.6 3.2 16 6.4 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH47477.1 - 0.00013 21.7 0.1 1.1 9.4 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFH47477.1 - 0.00095 18.9 17.6 0.057 13.1 0.6 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KFH47477.1 - 0.0033 17.4 3.8 3 7.7 0.0 4.9 3 2 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 KFH47477.1 - 0.0064 15.3 1.0 1.7 7.3 0.0 3.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) Suf PF05843.14 KFH47477.1 - 0.0086 16.1 0.2 1.8 8.5 0.0 3.9 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) SPOB_a PF14689.6 KFH47477.1 - 0.024 14.3 0.1 0.25 11.1 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain GILT PF03227.16 KFH47477.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) ChAPs PF09295.10 KFH47477.1 - 0.13 11.2 2.3 1.1 8.2 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Dioxygenase_C PF00775.21 KFH47478.1 - 5.8e-45 153.0 0.0 7.8e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KFH47478.1 - 3.3e-26 90.9 0.0 5.1e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KFH47478.1 - 0.019 15.2 0.0 0.097 13.0 0.0 2.2 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Thiolase_N PF00108.23 KFH47479.1 - 6.8e-76 255.0 5.1 1.1e-75 254.4 5.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH47479.1 - 8.4e-42 141.7 0.1 2.2e-41 140.4 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFH47479.1 - 0.0021 17.7 1.0 0.035 13.7 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KFH47479.1 - 0.025 14.7 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cadherin_tail PF15974.5 KFH47479.1 - 0.16 12.3 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Sulfotransfer_4 PF17784.1 KFH47480.1 - 2.8e-55 187.5 0.1 3.4e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH47480.1 - 0.00049 20.6 0.0 0.001 19.5 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Vac7 PF12751.7 KFH47481.1 - 5.5e-158 526.4 5.3 5.5e-158 526.4 5.3 2.8 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 Cu-oxidase_3 PF07732.15 KFH47482.1 - 1.4e-44 150.9 7.0 3e-42 143.4 0.2 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFH47482.1 - 1.1e-35 123.1 0.0 1.5e-34 119.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFH47482.1 - 2.5e-31 108.3 14.8 2.8e-30 104.9 2.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase MelC1 PF06236.11 KFH47482.1 - 0.0014 18.7 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosinase co-factor MelC1 Arylsulfotran_2 PF14269.6 KFH47483.1 - 2.5e-53 181.4 1.4 3.8e-53 180.8 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFH47483.1 - 2.5e-20 72.7 0.2 1e-19 70.7 0.2 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) S-l_SbsC_C PF18316.1 KFH47483.1 - 0.0057 17.1 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 S-layer protein SbsC C-terminal domain DUF21 PF01595.20 KFH47484.1 - 1.8e-34 119.0 0.0 2.8e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFH47484.1 - 4.1e-08 33.5 2.8 0.00051 20.4 0.2 2.9 2 0 0 2 2 2 2 CBS domain DHDPS PF00701.22 KFH47485.1 - 1.7e-25 89.3 0.0 2.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.12 KFH47485.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) zf_C2H2_10 PF18414.1 KFH47486.1 - 0.24 11.0 0.9 0.52 9.9 0.9 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger Mgm101p PF06420.12 KFH47487.1 - 3.2e-79 264.4 0.0 4.3e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Ndc1_Nup PF09531.10 KFH47487.1 - 0.22 10.2 5.4 0.25 10.0 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 KFH47487.1 - 9.7 6.0 10.6 14 5.5 10.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 KFH47488.1 - 5.2e-17 61.8 34.8 5.2e-17 61.8 34.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH47488.1 - 0.0082 15.0 2.1 0.0082 15.0 2.1 2.5 2 1 1 3 3 3 2 MFS_1 like family Gate PF07670.14 KFH47488.1 - 0.051 13.9 7.3 0.061 13.6 1.1 3.0 2 1 0 2 2 2 0 Nucleoside recognition DUF3185 PF11381.8 KFH47488.1 - 0.095 12.7 5.0 5.4 7.1 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3357 PF11837.8 KFH47489.1 - 0.59 10.6 3.3 2.6 8.5 0.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3357) RPE65 PF03055.15 KFH47490.1 - 1.6e-109 367.2 0.0 1.8e-109 367.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1664 PF07889.12 KFH47491.1 - 0.013 15.5 4.6 0.013 15.5 4.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HeLo PF14479.6 KFH47491.1 - 0.038 13.8 5.5 0.11 12.3 5.5 1.8 1 0 0 1 1 1 0 Prion-inhibition and propagation LETM1 PF07766.13 KFH47491.1 - 0.19 11.1 6.9 0.38 10.0 6.9 1.5 1 0 0 1 1 1 0 LETM1-like protein ComP_DUS PF16732.5 KFH47491.1 - 0.29 12.0 3.3 2.1 9.3 0.6 2.5 2 0 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF4200 PF13863.6 KFH47491.1 - 0.89 10.0 41.4 0.17 12.3 8.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KFH47491.1 - 1.7 7.9 23.8 3.1 7.0 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KFH47491.1 - 2.7 8.2 19.4 0.99 9.6 7.4 3.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KFH47491.1 - 2.8 7.1 12.2 6.6 5.9 12.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 KFH47491.1 - 3.2 6.2 13.7 0.41 9.2 8.7 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A NopRA1 PF16201.5 KFH47491.1 - 5.7 6.5 5.9 4 7.0 3.5 1.9 1 1 1 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Tho2 PF11262.8 KFH47491.1 - 8.7 5.4 16.4 1.2 8.3 11.9 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PIN_5 PF08745.11 KFH47491.1 - 8.8 5.7 9.5 0.57 9.6 3.1 2.0 2 0 0 2 2 2 0 PINc domain ribonuclease ODC_AZ PF02100.17 KFH47492.1 - 8.7e-45 151.4 0.2 1.2e-44 150.9 0.2 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Peptidase_C14 PF00656.22 KFH47493.1 - 1.1e-62 212.3 0.0 1.3e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF3730 PF12530.8 KFH47493.1 - 0.14 11.7 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Meth_synt_2 PF01717.18 KFH47494.1 - 1.1e-16 61.1 0.0 2.4e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFH47494.1 - 0.0049 16.4 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Yip1 PF04893.17 KFH47496.1 - 0.033 13.9 0.8 0.15 11.8 0.8 1.8 1 1 0 1 1 1 0 Yip1 domain Trimer_CC PF08954.11 KFH47497.1 - 0.034 13.7 2.1 0.057 13.0 0.1 2.5 2 0 0 2 2 2 0 Trimerisation motif ARID PF01388.21 KFH47498.1 - 4.6e-17 62.5 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SEN1_N PF12726.7 KFH47498.1 - 0.1 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal CBFD_NFYB_HMF PF00808.23 KFH47499.1 - 2.3e-17 63.0 0.2 3.7e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFH47499.1 - 0.00016 22.1 0.0 0.0007 20.0 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIS_C PF01096.18 KFH47500.1 - 0.27 11.1 1.2 0.97 9.3 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Methyltransf_23 PF13489.6 KFH47501.1 - 4.4e-13 49.4 0.0 7.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47501.1 - 3.1e-08 34.2 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH47501.1 - 3e-07 30.4 0.0 6.5e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47501.1 - 9.7e-07 29.5 0.0 5.6e-06 27.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47501.1 - 1.9e-06 28.5 0.0 3.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH47501.1 - 0.00029 20.3 0.0 0.00063 19.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Ribosomal_L16 PF00252.18 KFH47502.1 - 1.1e-44 151.6 0.0 1.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Glyoxalase PF00903.25 KFH47503.1 - 4.7e-37 127.1 0.1 1.9e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFH47503.1 - 1e-13 51.5 0.0 1.1e-05 25.7 0.0 3.7 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFH47503.1 - 0.00014 22.7 0.0 0.82 10.5 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFH47503.1 - 0.00016 21.6 0.9 0.054 13.4 0.3 3.7 3 1 0 3 3 3 1 Glyoxalase-like domain MoaF PF10703.9 KFH47503.1 - 0.024 14.6 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain Vps62 PF06101.11 KFH47504.1 - 6.3e-12 44.6 0.3 1.2e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Ysc84 PF04366.12 KFH47505.1 - 2.4e-41 140.5 0.2 4e-41 139.7 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KFH47505.1 - 8.8e-15 54.0 0.2 4.6e-14 51.8 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFH47505.1 - 1.3e-12 47.4 0.0 2.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFH47505.1 - 1.9e-11 43.4 0.0 4.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KFH47505.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) COX14 PF14880.6 KFH47507.1 - 1.7e-14 53.3 0.3 1.7e-14 53.3 0.3 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.11 KFH47507.1 - 0.024 14.2 0.4 0.045 13.3 0.4 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GPHR_N PF12537.8 KFH47507.1 - 0.075 13.1 0.4 0.29 11.2 0.0 2.2 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal ArfGap PF01412.18 KFH47508.1 - 6.5e-40 135.9 0.5 9.4e-40 135.3 0.5 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KFH47508.1 - 0.09 12.6 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Pex24p PF06398.11 KFH47509.1 - 5e-99 331.7 0.0 6.5e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SpoIIID PF12116.8 KFH47509.1 - 0.22 11.6 0.4 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein D Pam16 PF03656.13 KFH47510.1 - 9.1e-30 103.3 0.1 1.2e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Pam16 DUF2802 PF10975.8 KFH47510.1 - 0.06 13.5 0.2 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) TRAPPC-Trs85 PF12739.7 KFH47511.1 - 0.22 10.4 0.1 0.32 9.9 0.1 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2236 PF09995.9 KFH47512.1 - 2.5e-30 106.3 0.0 4.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Vps36_ESCRT-II PF11605.8 KFH47514.1 - 0.03 14.5 0.0 0.093 12.9 0.0 1.8 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 CHCH PF06747.13 KFH47516.1 - 0.00017 21.6 11.9 0.00027 21.0 11.9 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFH47516.1 - 0.0082 16.1 3.5 0.03 14.3 0.9 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KFH47516.1 - 0.01 16.2 3.0 0.016 15.5 3.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) GT-D PF08759.11 KFH47516.1 - 0.079 12.6 0.1 0.099 12.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Cmc1 PF08583.10 KFH47516.1 - 0.12 12.5 8.2 1.2 9.2 8.2 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like SUIM_assoc PF16619.5 KFH47516.1 - 0.18 11.9 0.2 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PRP38 PF03371.15 KFH47518.1 - 1.8e-57 194.0 0.0 2.2e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF357 PF04010.13 KFH47518.1 - 0.11 12.6 0.0 0.58 10.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF357) CDC45 PF02724.14 KFH47518.1 - 0.31 9.3 6.1 0.35 9.1 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KFH47518.1 - 1 9.0 12.2 1.5 8.4 12.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ketoacyl-synt PF00109.26 KFH47519.1 - 6.9e-65 219.1 0.1 6.9e-65 219.1 0.1 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFH47519.1 - 4.5e-52 176.6 0.0 9.2e-51 172.3 0.0 2.7 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KFH47519.1 - 1.1e-45 156.5 4.0 1.8e-45 155.9 4.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KFH47519.1 - 3.4e-42 144.7 0.0 7.5e-40 137.0 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFH47519.1 - 9.7e-23 80.4 0.0 4.7e-22 78.2 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFH47519.1 - 1.4e-18 67.5 0.0 6.8e-18 65.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KFH47519.1 - 1e-14 55.7 0.0 1e-12 49.2 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH47519.1 - 4.9e-13 49.2 0.0 3.2e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KFH47519.1 - 1.3e-11 44.6 0.1 6.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KFH47519.1 - 7.5e-11 41.9 0.1 8.7e-10 38.4 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KFH47519.1 - 1e-10 41.8 0.0 2.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFH47519.1 - 1.8e-09 38.1 0.3 1.9e-08 34.7 0.3 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFH47519.1 - 1.8e-09 38.2 0.0 8.3e-09 36.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH47519.1 - 6.4e-08 32.5 0.0 2e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47519.1 - 1e-07 32.5 0.0 4.2e-07 30.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KFH47519.1 - 6.2e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KFH47519.1 - 3.9e-05 23.3 0.0 8.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KFH47519.1 - 9.2e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KFH47519.1 - 0.001 18.5 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KFH47519.1 - 0.0088 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.18 KFH47519.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 KFH47519.1 - 0.033 13.3 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase SAT PF16073.5 KFH47519.1 - 1.1 9.0 6.7 0.065 13.0 0.5 2.2 2 0 0 2 2 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis TFIIIC_sub6 PF10419.9 KFH47521.1 - 3.3e-24 84.6 0.0 6.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain RTC PF01137.21 KFH47522.1 - 1.7e-50 171.3 0.0 3.5e-50 170.3 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Pyr_redox_3 PF13738.6 KFH47523.1 - 1.7e-17 63.6 0.1 2e-14 53.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH47523.1 - 7.3e-15 55.0 0.0 1.9e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH47523.1 - 2.4e-09 36.8 0.1 1.1e-06 28.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFH47523.1 - 4.7e-08 31.9 0.0 3.4e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH47523.1 - 7.7e-06 26.1 0.0 4.6e-05 23.6 0.0 2.4 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFH47523.1 - 5.3e-05 22.5 0.2 0.0046 16.1 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFH47523.1 - 9.1e-05 21.8 0.0 0.00063 19.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFH47523.1 - 0.00018 22.0 0.1 0.83 10.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH47523.1 - 0.00022 20.1 0.1 0.003 16.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFH47523.1 - 0.00032 19.9 0.0 0.0019 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFH47523.1 - 0.0025 17.2 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFH47523.1 - 0.0039 17.1 0.1 2.8 7.8 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFH47523.1 - 0.0077 15.6 0.2 0.062 12.7 0.0 2.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFH47523.1 - 0.0095 16.2 0.0 0.047 14.0 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KFH47523.1 - 0.013 15.1 1.1 0.31 10.6 1.1 2.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFH47523.1 - 0.029 14.4 0.1 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KFH47523.1 - 0.043 13.1 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KFH47523.1 - 0.043 13.9 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KFH47523.1 - 0.066 13.7 0.0 4.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding SnoaL_2 PF12680.7 KFH47523.1 - 0.1 13.2 0.3 0.1 13.2 0.3 2.7 3 0 0 3 3 2 0 SnoaL-like domain SelR PF01641.18 KFH47524.1 - 2.2e-47 160.1 0.0 3.8e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KFH47524.1 - 0.013 15.2 0.3 0.18 11.6 0.0 2.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KFH47524.1 - 0.13 12.4 0.3 0.3 11.3 0.3 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 KFH47524.1 - 0.14 11.7 1.1 1.2 8.7 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2076 PF09849.9 KFH47524.1 - 0.2 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-Mss51 PF13824.6 KFH47524.1 - 0.47 10.6 2.2 5 7.3 0.2 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 KFH47524.1 - 0.53 10.4 3.1 5.3 7.1 2.4 2.4 1 1 2 3 3 3 0 Double zinc ribbon Transferase PF02458.15 KFH47525.1 - 3.4e-08 32.6 0.0 3.3e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Transferase family CbiC PF02570.15 KFH47525.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase IMD PF08397.11 KFH47527.1 - 0.002 17.6 4.5 0.046 13.1 4.5 2.2 1 1 0 1 1 1 1 IRSp53/MIM homology domain SRRM_C PF15230.6 KFH47527.1 - 1.1 9.9 14.3 0.16 12.5 8.8 2.4 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Folliculin PF11704.8 KFH47527.1 - 5.2 6.9 6.3 8.3 6.3 0.2 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport VIR_N PF15912.5 KFH47528.1 - 0.037 13.6 1.0 0.077 12.6 1.0 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Zn_clus PF00172.18 KFH47528.1 - 0.098 12.8 12.9 1 9.6 12.9 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.7 KFH47529.1 - 1.7e-12 48.2 0.0 2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH47529.1 - 1.8e-09 37.8 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFH47529.1 - 0.0084 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein KH_1 PF00013.29 KFH47530.1 - 2.6e-95 312.2 28.5 7.6e-14 51.3 0.1 14.5 15 1 0 15 15 15 11 KH domain SLS PF14611.6 KFH47530.1 - 3.1e-11 43.5 4.4 0.096 12.5 0.0 6.9 4 1 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFH47530.1 - 9.2e-10 38.2 27.1 0.02 14.7 0.3 7.9 7 1 1 8 8 8 4 KH domain KH_4 PF13083.6 KFH47530.1 - 0.0044 16.9 10.0 2.8 7.9 0.0 5.9 6 0 0 6 6 6 2 KH domain BON PF04972.17 KFH47530.1 - 0.0053 17.0 3.1 14 6.0 0.0 4.8 4 0 0 4 4 4 2 BON domain MOEP19 PF16005.5 KFH47530.1 - 0.038 14.0 0.0 6.3 6.9 0.0 3.6 4 0 0 4 4 4 0 KH-like RNA-binding domain KH_5 PF13184.6 KFH47530.1 - 0.039 14.0 6.3 22 5.2 0.0 5.5 5 0 0 5 5 5 0 NusA-like KH domain DUF211 PF02680.14 KFH47530.1 - 0.69 10.1 3.7 13 6.0 0.3 3.4 4 0 0 4 4 4 0 Uncharacterized ArCR, COG1888 APH PF01636.23 KFH47531.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phosducin PF02114.16 KFH47532.1 - 1.5e-16 60.2 0.1 1.9e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KFH47532.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Acyl_transf_3 PF01757.22 KFH47533.1 - 6.5e-33 114.2 19.2 3.2e-32 112.0 19.2 2.1 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 KFH47533.1 - 0.00014 21.8 2.1 0.00014 21.8 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF418) COX16 PF14138.6 KFH47534.1 - 1.1e-32 112.4 0.2 1.5e-32 112.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 CLN3 PF02487.17 KFH47535.1 - 1.4e-39 136.3 2.7 2.4e-39 135.5 2.7 1.3 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KFH47535.1 - 0.82 8.5 43.8 6.3 5.6 42.1 2.4 1 1 0 1 1 1 0 Major Facilitator Superfamily RNR_inhib PF08591.10 KFH47536.1 - 2.2e-31 109.3 0.0 4.7e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF3649 PF12365.8 KFH47537.1 - 0.087 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Apolipoprotein PF01442.18 KFH47539.1 - 0.037 13.9 0.3 0.06 13.2 0.3 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ETRAMP PF09716.10 KFH47539.1 - 1.8 8.7 4.5 22 5.2 0.6 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Romo1 PF10247.9 KFH47540.1 - 1.1e-28 99.4 16.5 1.3e-28 99.1 16.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFH47540.1 - 0.00051 20.4 4.3 0.00064 20.1 4.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KFH47540.1 - 1.2 9.3 11.3 7 6.9 11.3 1.9 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 KFH47540.1 - 6.2 6.7 9.1 6.1 6.7 2.4 2.6 2 1 0 2 2 2 0 Glycine-zipper domain Amidohydro_1 PF01979.20 KFH47541.1 - 5.6e-18 65.4 0.1 1.7e-16 60.5 0.1 2.6 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH47541.1 - 8.4e-10 38.7 0.2 7.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family OCD_Mu_crystall PF02423.15 KFH47542.1 - 1.3e-13 50.6 0.0 3.9e-09 35.9 0.0 2.9 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFH47542.1 - 0.029 14.4 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PYRIN PF02758.16 KFH47542.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain RrnaAD PF00398.20 KFH47543.1 - 3.6e-65 219.7 0.0 4.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFH47543.1 - 8.3e-07 29.6 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47543.1 - 3.2e-05 24.5 0.0 7.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFH47543.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KFH47543.1 - 0.0026 17.6 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KFH47543.1 - 0.0058 16.0 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KFH47543.1 - 0.0079 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Nop53 PF07767.11 KFH47543.1 - 0.0098 15.3 0.3 0.015 14.7 0.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Methyltransf_12 PF08242.12 KFH47543.1 - 0.015 16.1 0.1 0.046 14.5 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFH47543.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_lid_4 PF17864.1 KFH47543.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_28 PF02636.17 KFH47543.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Drf_GBD PF06371.13 KFH47546.1 - 2.1e-15 56.8 0.9 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain TB2_DP1_HVA22 PF03134.19 KFH47548.1 - 1e-21 76.7 8.9 9.5e-21 73.5 8.9 2.1 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Lipase_GDSL_2 PF13472.6 KFH47549.1 - 1.9e-14 54.5 1.9 2.5e-14 54.1 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KFH47549.1 - 0.00012 22.3 0.0 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH47549.1 - 0.00016 21.7 0.3 0.00029 20.9 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase EF-hand_9 PF14658.6 KFH47549.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain UCR_hinge PF02320.16 KFH47550.1 - 8.8e-27 93.1 10.5 8.8e-27 93.1 10.5 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein BUD22 PF09073.10 KFH47550.1 - 0.07 12.5 14.9 0.077 12.3 14.9 1.0 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 KFH47550.1 - 0.09 12.6 13.9 0.11 12.3 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 KFH47550.1 - 0.42 10.7 2.4 0.42 10.7 2.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 KFH47550.1 - 0.54 9.2 6.2 0.57 9.1 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4471 PF14740.6 KFH47550.1 - 0.59 9.3 4.2 0.73 9.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CDC45 PF02724.14 KFH47550.1 - 0.7 8.1 11.2 0.72 8.1 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFH47550.1 - 0.8 7.8 18.9 0.84 7.8 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family PPL5 PF18168.1 KFH47550.1 - 1.4 8.1 5.2 1.7 7.9 5.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Lin-8 PF03353.15 KFH47550.1 - 1.5 8.3 13.8 1.7 8.1 13.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_phi PF04931.13 KFH47550.1 - 1.7 6.7 24.5 2 6.4 24.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 KFH47550.1 - 1.7 8.8 8.9 2.3 8.4 8.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 KFH47550.1 - 1.8 7.9 10.3 2.1 7.7 10.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2428 PF10350.9 KFH47550.1 - 1.9 7.7 5.3 2.7 7.2 5.3 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) SDA1 PF05285.12 KFH47550.1 - 2 7.7 19.2 2.3 7.6 19.2 1.1 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 KFH47550.1 - 2 7.1 14.7 2.3 6.9 14.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 KFH47550.1 - 2.1 7.1 7.1 2.2 7.0 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GET2 PF08690.10 KFH47550.1 - 2.1 7.9 7.6 2.7 7.6 7.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 KFH47550.1 - 2.1 7.0 11.3 2.5 6.8 11.3 1.0 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KFH47550.1 - 2.3 6.9 8.3 2.3 6.9 8.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 KFH47550.1 - 2.4 7.1 3.7 2.7 6.9 3.7 1.1 1 0 0 1 1 1 0 CLN3 protein tRNA_bind_2 PF13725.6 KFH47550.1 - 3.6 7.2 12.1 4.8 6.8 12.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain DUF4045 PF13254.6 KFH47550.1 - 3.7 7.1 14.4 4.3 6.9 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 KFH47550.1 - 3.9 6.4 5.6 4.3 6.2 5.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CobT PF06213.12 KFH47550.1 - 4.3 6.6 19.8 5.3 6.3 19.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.6 KFH47550.1 - 4.9 5.8 9.7 5.4 5.6 9.7 1.1 1 0 0 1 1 1 0 Raftlin RNA_polI_A34 PF08208.11 KFH47550.1 - 5.6 7.0 15.9 6.4 6.8 15.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RRN3 PF05327.11 KFH47550.1 - 6.6 5.2 9.2 7 5.1 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP70 PF00012.20 KFH47550.1 - 7.1 4.7 12.2 8 4.5 12.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Neur_chan_memb PF02932.16 KFH47550.1 - 8.1 6.4 6.8 9.1 6.3 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KFH47550.1 - 8.7 4.3 9.7 9.6 4.2 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PDCD7 PF16021.5 KFH47551.1 - 0.15 11.2 9.4 0.27 10.3 9.4 1.3 1 0 0 1 1 1 0 Programmed cell death protein 7 PLN_propep PF16485.5 KFH47551.1 - 2.5 7.9 5.1 0.49 10.1 0.7 2.2 2 0 0 2 2 2 0 Protealysin propeptide F-box PF00646.33 KFH47552.1 - 0.00011 21.9 0.4 0.00028 20.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.6 KFH47552.1 - 0.079 13.6 0.1 2.4 9.0 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat WSC PF01822.19 KFH47553.1 - 4.5e-11 42.8 7.9 4.5e-11 42.8 7.9 2.8 2 1 0 2 2 2 1 WSC domain adh_short_C2 PF13561.6 KFH47554.1 - 1.2e-60 205.0 0.4 1.9e-60 204.3 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH47554.1 - 1.4e-49 168.2 0.5 2e-49 167.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH47554.1 - 5.1e-12 46.1 0.1 7.5e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH47554.1 - 4.9e-06 26.2 0.1 9.9e-06 25.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH47554.1 - 0.0022 17.5 0.1 0.004 16.6 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFH47554.1 - 0.0056 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KFH47554.1 - 0.037 14.7 0.1 0.085 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF5612 PF18462.1 KFH47554.1 - 0.78 9.5 3.1 2.3 8.0 0.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5612) WW PF00397.26 KFH47555.1 - 5.3e-08 32.8 3.2 1.3e-07 31.6 3.2 1.7 1 0 0 1 1 1 1 WW domain Ribosomal_L50 PF10501.9 KFH47556.1 - 2.1e-11 43.9 0.0 4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.27 KFH47556.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 SAP domain DOPA_dioxygen PF08883.11 KFH47557.1 - 2.2e-44 150.0 0.0 2.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family adh_short PF00106.25 KFH47558.1 - 3.6e-22 78.8 0.0 6.1e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH47558.1 - 5.8e-16 58.8 0.1 7.1e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH47558.1 - 3.3e-06 27.1 0.0 5.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH47558.1 - 3.8e-05 23.3 0.2 0.00016 21.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH47558.1 - 0.096 12.1 0.0 0.78 9.1 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KFH47559.1 - 3.7e-33 114.7 2.6 5.2e-33 114.2 0.4 2.1 1 1 2 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47559.1 - 3.6e-07 30.2 10.6 6.8e-07 29.3 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.26 KFH47559.1 - 0.079 13.2 3.9 0.2 11.9 3.9 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain LSM PF01423.22 KFH47560.1 - 7.7e-12 44.7 0.0 1.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFH47560.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Gly_transf_sug PF04488.15 KFH47561.1 - 1.5e-12 48.0 0.0 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Jiv90 PF14901.6 KFH47561.1 - 0.18 12.0 0.9 0.3 11.3 0.3 1.6 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone RAI1 PF08652.11 KFH47562.1 - 2.5e-28 98.0 0.0 4.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease MMR_HSR1 PF01926.23 KFH47563.1 - 1.7e-16 60.3 0.3 7.2e-15 55.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFH47563.1 - 2.6e-07 30.3 0.3 3e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFH47563.1 - 2.8e-06 27.3 0.2 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFH47563.1 - 0.0096 16.0 0.2 0.62 10.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KFH47563.1 - 0.042 12.8 0.2 0.085 11.8 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KFH47563.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 KFH47563.1 - 0.13 11.8 0.1 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-RanBP PF00641.18 KFH47564.1 - 1.4e-18 65.9 12.5 5.4e-11 41.6 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KFH47564.1 - 3.4e-08 33.2 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KFH47564.1 - 7.6e-07 29.8 0.0 1.1e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Rox3 PF08633.10 KFH47565.1 - 1.2e-69 234.7 0.0 1.6e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Glyco_hydro_76 PF03663.14 KFH47566.1 - 2.4e-139 464.9 6.5 2.8e-139 464.7 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFH47566.1 - 0.038 13.1 8.6 0.37 9.8 0.3 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Transglut_core PF01841.19 KFH47567.1 - 2.4e-11 44.1 0.3 6.1e-11 42.8 0.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KFH47567.1 - 1.5e-07 30.9 0.1 3.7e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFH47567.1 - 0.0006 19.4 0.1 0.0006 19.4 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFH47567.1 - 0.021 14.7 0.2 0.049 13.5 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain SARAF PF06682.12 KFH47567.1 - 7.1 6.2 16.0 0.14 11.8 8.5 1.9 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FMO-like PF00743.19 KFH47568.1 - 2.1e-34 118.8 0.0 1.8e-19 69.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFH47568.1 - 2.4e-13 50.0 0.0 5e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH47568.1 - 1e-12 47.9 0.4 1.1e-06 28.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH47568.1 - 1.8e-10 40.5 0.0 5.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFH47568.1 - 5.4e-08 32.8 0.2 0.0052 16.4 0.0 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFH47568.1 - 1.1e-06 28.1 0.0 0.00017 20.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFH47568.1 - 2.6e-06 27.5 0.0 7.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFH47568.1 - 7.4e-06 26.0 2.8 0.00024 21.1 0.3 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFH47568.1 - 0.0019 17.0 0.5 0.069 11.8 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KFH47568.1 - 0.0048 17.4 0.6 2.2 8.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KFH47568.1 - 0.013 14.9 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KFH47568.1 - 0.018 15.1 0.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFH47568.1 - 0.042 13.1 0.3 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KFH47568.1 - 0.13 11.2 0.3 4.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KFH47568.1 - 0.2 12.0 0.1 0.48 10.7 0.0 1.6 2 0 0 2 2 1 0 TrkA-N domain FAD_binding_2 PF00890.24 KFH47568.1 - 0.25 10.4 1.2 0.68 8.9 0.1 2.2 3 1 1 4 4 4 0 FAD binding domain SelP_N PF04592.14 KFH47569.1 - 0.2 11.0 14.4 0.36 10.2 14.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RRM_1 PF00076.22 KFH47570.1 - 3.3e-33 113.3 0.0 1.9e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH47570.1 - 0.0088 15.6 0.0 0.09 12.4 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH47570.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 KFH47570.1 - 0.042 13.5 0.9 3.2 7.5 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RmlD_sub_bind PF04321.17 KFH47571.1 - 1.7e-52 178.3 0.0 2.1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFH47571.1 - 9e-23 81.0 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH47571.1 - 1.3e-11 44.5 0.0 2.6e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFH47571.1 - 1.9e-09 37.1 0.3 2.5e-06 26.9 0.3 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFH47571.1 - 7.2e-09 35.2 0.0 2.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KFH47571.1 - 3.9e-08 32.6 0.0 1.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFH47571.1 - 0.019 14.5 1.2 2.2 7.8 0.4 3.0 2 1 0 2 2 2 0 NmrA-like family KR PF08659.10 KFH47571.1 - 0.29 11.0 1.6 9.9 6.0 1.6 2.4 1 1 0 1 1 1 0 KR domain ANAPC8 PF04049.13 KFH47572.1 - 1.2e-53 180.9 0.5 1.2e-53 180.9 0.5 2.5 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KFH47572.1 - 1.5e-20 71.6 11.0 6.8e-05 22.8 0.0 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFH47572.1 - 2.2e-19 68.4 7.5 9e-05 22.1 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH47572.1 - 4e-12 45.3 15.5 0.048 13.8 0.0 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFH47572.1 - 4.4e-11 42.6 12.1 0.0056 17.4 0.1 8.9 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFH47572.1 - 2.1e-08 33.7 0.1 1.1e-06 28.2 0.1 3.0 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 KFH47572.1 - 4.5e-08 33.6 3.0 2.4e-05 24.9 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFH47572.1 - 8.8e-06 25.4 6.0 0.032 14.3 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFH47572.1 - 1.5e-05 25.2 18.4 0.18 12.1 0.1 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH47572.1 - 8.5e-05 23.0 8.9 5.6 7.6 0.0 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH47572.1 - 0.0001 22.4 10.4 0.051 13.8 0.7 5.5 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFH47572.1 - 0.00019 21.6 0.0 6.4 7.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFH47572.1 - 0.008 16.0 4.1 2.1 8.3 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH47572.1 - 0.031 14.4 14.6 2.2 8.5 0.3 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH47572.1 - 0.032 13.6 0.4 0.032 13.6 0.4 2.6 3 0 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 KFH47572.1 - 0.14 12.8 21.0 9.8 7.1 0.5 8.1 10 0 0 10 10 9 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KFH47572.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF3856 PF12968.7 KFH47572.1 - 0.33 11.0 6.3 1.1 9.3 0.1 3.2 3 1 1 4 4 3 0 Domain of Unknown Function (DUF3856) Abhydrolase_1 PF00561.20 KFH47574.1 - 8.3e-12 45.3 0.1 1.2e-08 35.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH47574.1 - 4.8e-09 35.8 0.0 1.3e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 GATA PF00320.27 KFH47575.1 - 6.2e-05 22.5 2.5 0.0066 16.0 0.4 2.5 2 0 0 2 2 2 2 GATA zinc finger HCO3_cotransp PF00955.21 KFH47576.1 - 1.2e-77 261.9 9.6 7.4e-39 133.9 0.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family Mito_carr PF00153.27 KFH47577.1 - 6.3e-60 199.1 1.0 3.3e-19 68.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.29 KFH47578.1 - 0.0029 18.1 0.1 0.0066 16.9 0.1 1.6 1 0 0 1 1 1 1 PH domain Methyltransf_32 PF13679.6 KFH47579.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KFH47580.1 - 5e-53 179.7 0.3 6.4e-53 179.3 0.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFH47580.1 - 3.7e-33 114.0 0.0 8.4e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KFH47580.1 - 0.00023 21.4 0.0 0.00057 20.1 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KFH47580.1 - 0.017 15.3 0.1 0.042 14.0 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KFH47580.1 - 0.073 12.3 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFH47580.1 - 0.094 12.1 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RsbU_N PF08673.10 KFH47580.1 - 0.18 11.9 0.2 0.44 10.7 0.1 1.7 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Ribosomal_L4 PF00573.22 KFH47581.1 - 1.6e-33 116.0 0.1 2.2e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFH47581.1 - 2.8e-27 94.5 1.6 2.8e-27 94.5 1.6 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain UCH PF00443.29 KFH47582.1 - 7.6e-24 84.6 0.0 1.1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFH47582.1 - 1.8e-12 47.4 0.2 3.8e-12 46.4 0.2 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFH47582.1 - 0.0095 15.6 0.0 0.047 13.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 KFH47582.1 - 0.12 12.7 0.2 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) CENP-B_dimeris PF09026.10 KFH47582.1 - 2 8.9 10.1 4.7 7.6 10.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KFH47582.1 - 7.1 7.1 10.9 0.65 10.4 5.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 KFH47583.1 - 1.3e-42 145.1 7.9 1.3e-42 145.1 7.9 1.5 2 0 0 2 2 2 1 Protein trafficking PGA2 Smr PF01713.21 KFH47583.1 - 0.015 15.6 0.2 0.043 14.2 0.0 1.8 2 0 0 2 2 2 0 Smr domain LdpA_C PF12617.8 KFH47583.1 - 0.27 10.8 2.0 0.41 10.2 2.0 1.6 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal Pol_alpha_B_N PF08418.10 KFH47584.1 - 1.7e-75 254.2 0.0 2.2e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KFH47584.1 - 1.5e-36 125.8 0.2 2.6e-36 125.0 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B IF4E PF01652.18 KFH47586.1 - 6.4e-54 182.1 0.0 8.7e-54 181.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MTS PF05175.14 KFH47587.1 - 2.5e-07 30.4 0.0 5.8e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KFH47587.1 - 3e-07 30.4 0.0 6e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47587.1 - 0.0005 20.7 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KFH47587.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmC_N PF17827.1 KFH47587.1 - 0.0024 18.4 0.6 0.0067 17.0 0.6 1.8 1 1 0 1 1 1 1 PrmC N-terminal domain Methyltransf_10 PF05971.12 KFH47587.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase UPF0020 PF01170.18 KFH47587.1 - 0.017 14.8 0.0 0.29 10.8 0.0 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 KFH47587.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFH47587.1 - 0.085 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 KFH47587.1 - 0.15 11.5 0.0 2.5 7.5 0.0 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa PrmA PF06325.13 KFH47587.1 - 0.29 10.5 0.0 0.4 10.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S14 PF00253.21 KFH47588.1 - 2.4e-14 52.8 3.3 3.1e-14 52.4 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KFH47588.1 - 0.009 15.9 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Phage_Nu1 PF07471.12 KFH47588.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 PTR2 PF00854.21 KFH47589.1 - 9.9e-76 255.1 2.0 1.3e-75 254.8 2.0 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFH47589.1 - 2.7e-05 23.3 19.3 0.016 14.1 0.6 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily HET PF06985.11 KFH47590.1 - 9.8e-10 39.0 0.0 2.3e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ELO PF01151.18 KFH47591.1 - 1.5e-62 211.4 16.8 1.8e-62 211.1 16.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.32 KFH47592.1 - 6.8e-27 93.2 22.7 0.00052 20.8 0.1 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47592.1 - 8.7e-07 29.2 0.5 4.1 7.8 0.0 7.3 5 2 4 9 9 8 1 Anaphase-promoting complex subunit 4 WD40 domain Mub_B2 PF17966.1 KFH47592.1 - 0.0016 19.1 0.3 0.1 13.3 0.2 2.9 2 1 0 2 2 2 1 Mub B2-like domain PD40 PF07676.12 KFH47592.1 - 0.047 13.6 0.1 25 5.0 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Methyltransf_32 PF13679.6 KFH47593.1 - 1.6e-23 83.5 0.0 2.9e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain HSBP1 PF06825.12 KFH47594.1 - 7.1e-16 57.8 0.5 8.3e-16 57.6 0.5 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 KFH47594.1 - 0.00018 21.8 0.1 0.00026 21.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KFH47594.1 - 0.023 14.9 0.6 0.029 14.6 0.6 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain MMS19_C PF12460.8 KFH47594.1 - 0.024 13.8 0.2 0.024 13.7 0.2 1.0 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Matrilin_ccoil PF10393.9 KFH47594.1 - 0.038 13.8 0.6 0.34 10.8 0.6 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DNA_repr_REX1B PF14966.6 KFH47594.1 - 0.041 14.5 0.2 0.05 14.3 0.2 1.3 1 0 0 1 1 1 0 DNA repair REX1-B DUF1664 PF07889.12 KFH47594.1 - 0.041 13.9 0.2 0.049 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CHD5 PF04420.14 KFH47594.1 - 0.17 11.7 0.8 0.2 11.5 0.8 1.3 1 1 0 1 1 1 0 CHD5-like protein TPALS PF18178.1 KFH47595.1 - 0.073 12.5 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family DEAD PF00270.29 KFH47596.1 - 1.2e-46 158.7 0.0 3.5e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH47596.1 - 3.9e-32 110.9 0.0 8.1e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH47596.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFH47596.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.22 KFH47597.1 - 4.6e-23 80.7 0.1 5.1e-23 80.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFH47597.1 - 0.046 13.9 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KFH47597.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain GLE1 PF07817.13 KFH47599.1 - 5.5e-59 199.4 0.0 7.6e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein DKCLD PF08068.12 KFH47600.1 - 1.1e-34 118.3 0.2 1.1e-32 111.9 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KFH47600.1 - 4.8e-24 85.4 0.4 5.4e-21 75.5 0.4 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFH47600.1 - 1.1e-21 76.7 1.0 2.2e-21 75.8 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KFH47600.1 - 4.1e-21 74.7 0.5 9.4e-21 73.6 0.5 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFH47600.1 - 0.00033 20.8 0.0 0.00084 19.5 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DUF1179 PF06678.11 KFH47600.1 - 0.39 10.7 3.4 0.8 9.7 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Med19 PF10278.9 KFH47600.1 - 0.58 10.1 9.9 0.97 9.3 9.4 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zf-rbx1 PF12678.7 KFH47601.1 - 4.1e-11 43.0 1.3 1.1e-10 41.7 1.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFH47601.1 - 4e-07 30.3 9.0 2.5e-06 27.7 9.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFH47601.1 - 1.4e-06 28.0 1.2 2.4e-06 27.3 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH47601.1 - 2.9e-06 27.2 0.6 3.8e-05 23.6 0.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFH47601.1 - 4.5e-06 26.4 5.2 2e-05 24.3 2.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH47601.1 - 5e-06 26.4 1.9 1.2e-05 25.1 2.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH47601.1 - 8.9e-05 22.3 0.3 8.9e-05 22.3 0.3 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFH47601.1 - 0.0009 19.1 1.6 0.0009 19.1 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFH47601.1 - 0.00093 18.8 0.9 0.0021 17.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFH47601.1 - 0.016 14.9 0.8 0.016 14.9 0.8 3.2 3 0 0 3 3 3 0 RING-like zinc finger PQ-loop PF04193.14 KFH47601.1 - 0.025 14.4 0.3 0.073 12.8 0.3 1.8 1 0 0 1 1 1 0 PQ loop repeat zf-C3H2C3 PF17122.5 KFH47601.1 - 0.17 12.0 4.9 1.4 9.0 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger DUF2921 PF11145.8 KFH47601.1 - 0.27 9.0 0.2 0.44 8.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 KFH47601.1 - 0.3 11.2 6.9 0.054 13.6 2.6 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFH47601.1 - 7.6 6.8 5.2 24 5.2 5.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain WD40 PF00400.32 KFH47602.1 - 6.5e-22 77.4 4.7 6.6e-05 23.6 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 KFH47602.1 - 0.0036 16.7 0.0 0.044 13.1 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 KFH47602.1 - 0.021 15.1 0.0 1.2 9.4 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFH47602.1 - 0.067 13.7 0.5 3.5 8.2 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain Nha1_C PF08619.10 KFH47602.1 - 1.1 8.3 15.2 2 7.5 15.2 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM176 PF14851.6 KFH47602.1 - 2.8 7.6 6.0 6.2 6.5 6.0 1.5 1 0 0 1 1 1 0 FAM176 family WD40 PF00400.32 KFH47603.1 - 4.3e-16 59.0 14.4 3.3e-08 34.1 1.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat NLE PF08154.12 KFH47603.1 - 6.6e-14 52.2 0.2 1.1e-13 51.5 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain RNB PF00773.19 KFH47604.1 - 1.4e-78 264.5 0.0 2.6e-78 263.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KFH47604.1 - 1.8e-25 89.0 0.0 6e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KFH47604.1 - 3.4e-25 87.9 0.0 7.7e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFH47604.1 - 6.3e-07 29.5 0.0 0.0021 18.2 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFH47604.1 - 0.0065 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain SDP_N PF12278.8 KFH47604.1 - 0.088 12.9 0.0 0.088 12.9 0.0 3.1 2 1 1 3 3 3 0 Sex determination protein N terminal Ric8 PF10165.9 KFH47607.1 - 6.7e-76 256.2 0.0 2.5e-75 254.3 0.0 1.7 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn SPC22 PF04573.12 KFH47608.1 - 2.8e-39 134.3 0.1 5.9e-38 130.0 0.1 2.0 1 1 0 1 1 1 1 Signal peptidase subunit MKT1_C PF12246.8 KFH47610.1 - 1.3e-65 221.0 0.0 1.7e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KFH47610.1 - 6.2e-32 109.8 0.0 1.3e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KFH47610.1 - 0.00015 22.2 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain COX14 PF14880.6 KFH47611.1 - 0.047 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly FAM35_C PF15793.5 KFH47611.1 - 0.14 11.5 0.2 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein family FAM35, C-terminal WD40 PF00400.32 KFH47612.1 - 2.8e-28 97.6 3.7 2.8e-06 27.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KFH47612.1 - 6.8e-26 90.3 0.1 2.6e-25 88.4 0.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KFH47612.1 - 2.6e-05 24.4 0.3 0.081 13.2 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Urm1 PF09138.11 KFH47613.1 - 4.1e-33 113.6 0.0 4.6e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFH47613.1 - 0.00022 21.8 0.0 0.00029 21.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family DIOX_N PF14226.6 KFH47614.1 - 9.5e-23 81.2 0.0 1.5e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH47614.1 - 2.7e-14 53.5 0.0 5.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily rve_3 PF13683.6 KFH47614.1 - 0.11 12.3 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Rabaptin PF03528.15 KFH47615.1 - 0.036 12.8 0.5 0.045 12.5 0.5 1.1 1 0 0 1 1 1 0 Rabaptin NmrA PF05368.13 KFH47616.1 - 3e-78 262.6 0.0 3.8e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFH47616.1 - 1.2e-07 31.8 0.0 3.2e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF2498 PF10692.9 KFH47616.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Nucleo_P87 PF07267.11 KFH47616.1 - 0.41 9.5 0.9 0.54 9.1 0.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mtf2_C PF14061.6 KFH47617.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KFH47617.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Occludin_ELL PF07303.13 KFH47617.1 - 1.9 9.3 10.3 4.6 8.0 1.3 2.7 2 0 0 2 2 2 0 Occludin homology domain Golgin_A5 PF09787.9 KFH47617.1 - 2 7.8 24.6 1.1 8.7 9.5 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 IFT57 PF10498.9 KFH47617.1 - 5.6 5.8 21.5 0.028 13.4 6.4 2.7 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Vps54 PF07928.12 KFH47619.1 - 4.2e-51 172.9 0.5 1.7e-50 170.9 0.0 2.3 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 KFH47619.1 - 8.8e-05 21.9 2.8 0.00012 21.5 0.7 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF4363 PF14276.6 KFH47619.1 - 0.22 11.7 4.9 6.9 6.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) FUSC PF04632.12 KFH47619.1 - 8.9 4.7 11.8 0.34 9.4 2.1 2.5 2 1 0 3 3 3 0 Fusaric acid resistance protein family Fcf1 PF04900.12 KFH47620.1 - 1.1e-34 118.8 0.3 2.2e-34 117.8 0.1 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KFH47620.1 - 9.8e-13 48.4 1.0 1.4e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 PIN like domain GCV_T PF01571.21 KFH47620.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4706 PF15797.5 KFH47620.1 - 0.12 12.9 0.1 1 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) Fungal_trans PF04082.18 KFH47621.1 - 9.9e-22 77.2 1.2 1.5e-21 76.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47621.1 - 3.8e-07 30.1 13.3 7.1e-07 29.2 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EphA2_TM PF14575.6 KFH47622.1 - 7.7e-05 23.5 0.0 0.0002 22.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4048 PF13257.6 KFH47623.1 - 3e-05 24.0 19.8 3e-05 24.0 19.8 4.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4048) CENP-H PF05837.12 KFH47623.1 - 0.14 12.6 1.4 0.42 11.0 1.4 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Dicty_REP PF05086.12 KFH47623.1 - 0.22 9.5 1.4 0.32 8.9 1.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.7 KFH47624.1 - 1.2e-32 112.3 0.2 2.1e-11 44.2 0.6 3.7 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH47624.1 - 1.7e-29 101.8 0.2 5.4e-09 36.4 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH47624.1 - 2.6e-21 73.4 1.5 0.0043 17.5 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFH47624.1 - 1.8e-19 69.5 5.0 4.9e-05 23.5 0.2 6.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFH47624.1 - 4.3e-18 64.9 2.5 0.00027 21.3 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat ECH_2 PF16113.5 KFH47625.1 - 2.2e-126 421.9 0.0 2.9e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFH47625.1 - 1.9e-27 96.2 0.0 3e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Fungal_trans_2 PF11951.8 KFH47626.1 - 4.7e-17 61.9 0.0 5.7e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain GAS2 PF02187.17 KFH47627.1 - 2.6e-07 30.6 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Pmp3 PF01679.17 KFH47628.1 - 3.6e-09 36.7 9.5 3.6e-09 36.7 9.5 1.9 2 1 0 2 2 2 1 Proteolipid membrane potential modulator DUF2244 PF10003.9 KFH47628.1 - 0.2 11.3 0.4 0.26 11.0 0.4 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Dak1 PF02733.17 KFH47629.1 - 4.5e-104 347.7 6.1 6.1e-104 347.3 6.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KFH47629.1 - 3.3e-47 160.6 0.2 3.3e-47 160.6 0.2 1.6 2 0 0 2 2 2 1 DAK2 domain Fungal_trans PF04082.18 KFH47630.1 - 2e-22 79.5 0.0 5.7e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47630.1 - 1.3e-10 41.2 11.4 2.3e-10 40.4 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 KFH47630.1 - 0.029 13.1 0.1 0.056 12.1 0.1 1.4 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Pkinase PF00069.25 KFH47631.1 - 1.7e-69 234.1 0.0 2.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47631.1 - 2.4e-49 167.9 0.0 3.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH47631.1 - 9.5e-06 24.6 0.0 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH47631.1 - 1e-05 25.0 0.0 9.3e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFH47631.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI2 PF06432.11 KFH47632.1 - 1.2 8.6 5.1 1.6 8.1 5.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase LTV PF04180.14 KFH47633.1 - 7.3e-125 417.7 16.6 8.3e-125 417.5 16.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF676 PF05057.14 KFH47634.1 - 0.00016 21.3 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFH47634.1 - 0.00035 20.4 0.1 0.0012 18.6 0.1 1.8 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFH47634.1 - 0.006 17.2 2.0 0.006 17.2 2.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH47634.1 - 0.0088 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFH47634.1 - 0.048 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3510 PF12022.8 KFH47634.1 - 0.076 13.4 7.0 0.21 12.0 7.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) UPF0227 PF05728.12 KFH47634.1 - 0.22 11.4 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) OmpH PF03938.14 KFH47634.1 - 0.68 10.3 22.0 1.1 9.6 22.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KFH47634.1 - 2.4 7.6 7.8 3.6 7.1 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KFH47634.1 - 7.1 4.4 7.1 9.8 4.0 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cohesin_load PF10345.9 KFH47635.1 - 2e-90 304.0 6.7 6.4e-72 242.9 4.2 2.1 2 0 0 2 2 2 2 Cohesin loading factor POT1 PF02765.17 KFH47636.1 - 2.8e-09 36.9 0.0 4.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 NADH_B2 PF14813.6 KFH47637.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF5301 PF17225.3 KFH47637.1 - 0.51 10.8 0.1 0.51 10.8 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Zn_clus PF00172.18 KFH47638.1 - 1.3e-06 28.4 13.8 1.3e-06 28.4 10.5 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3014 PF11219.8 KFH47638.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Pox_A_type_inc PF04508.12 KFH47638.1 - 0.46 10.4 3.6 1.1 9.2 3.6 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TIMELESS PF04821.14 KFH47639.1 - 1.1e-88 297.2 0.1 5.1e-88 294.9 0.1 2.3 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KFH47639.1 - 6.2e-35 121.4 4.3 6.2e-35 121.4 4.3 3.7 3 2 1 4 4 4 1 Timeless protein C terminal region Cnd1_N PF12922.7 KFH47639.1 - 2.1 8.2 12.4 0.58 10.0 0.2 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1, N-term Tom7 PF08038.12 KFH47640.1 - 2.4e-20 71.9 0.1 2.7e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 TOM7 family Malic_M PF03949.15 KFH47642.1 - 8.6e-97 323.4 0.0 1.2e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFH47642.1 - 2.2e-72 242.7 0.0 3.4e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Zn_clus PF00172.18 KFH47643.1 - 9.6e-08 32.0 5.7 1.8e-07 31.2 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH47643.1 - 0.065 12.0 0.1 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pkinase PF00069.25 KFH47644.1 - 1.3e-69 234.5 0.0 1.7e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47644.1 - 4.7e-36 124.4 0.0 9.9e-36 123.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH47644.1 - 0.0093 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFH47644.1 - 0.0094 15.3 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFH47644.1 - 0.065 12.0 0.0 0.065 12.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KFH47644.1 - 0.083 12.5 0.1 0.083 12.5 0.1 1.5 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KFH47644.1 - 0.23 10.3 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Homeodomain PF00046.29 KFH47645.1 - 1.1e-17 63.5 2.0 2e-17 62.8 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFH47645.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain IPP-2 PF04979.14 KFH47645.1 - 0.23 12.2 3.0 0.89 10.3 3.0 2.1 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Aconitase PF00330.20 KFH47646.1 - 8.2e-106 354.8 0.4 7.1e-105 351.7 0.4 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFH47646.1 - 2.5e-24 86.1 0.0 5.6e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain polyprenyl_synt PF00348.17 KFH47647.1 - 5.5e-91 304.1 0.0 6.8e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Utp13 PF08625.11 KFH47648.1 - 2.6e-51 173.3 0.2 4.2e-51 172.6 0.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KFH47648.1 - 1e-47 159.1 27.4 5.4e-06 27.0 0.1 11.9 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47648.1 - 4.4e-11 42.9 9.7 0.6 10.5 0.0 8.1 6 4 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFH47648.1 - 9.9e-05 21.3 0.1 4.2 6.0 0.0 4.7 4 1 1 5 5 5 2 Nup133 N terminal like Nup160 PF11715.8 KFH47648.1 - 0.00028 19.7 6.0 0.7 8.5 0.1 4.9 2 2 1 5 5 5 3 Nucleoporin Nup120/160 Fn_bind PF02986.14 KFH47648.1 - 0.45 10.3 2.7 2.8 7.7 2.6 2.3 2 0 0 2 2 2 0 Fibronectin binding repeat ZZ PF00569.17 KFH47649.1 - 0.0053 16.6 1.0 2.5 8.0 0.0 3.0 3 0 0 3 3 3 2 Zinc finger, ZZ type DUF1272 PF06906.11 KFH47649.1 - 0.76 9.9 3.2 14 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) MIP PF00230.20 KFH47650.1 - 4.7e-41 141.0 6.0 6.3e-41 140.6 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_M41 PF01434.18 KFH47652.1 - 1.9e-69 233.4 0.1 2.9e-69 232.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFH47652.1 - 1.3e-41 142.1 0.0 5.7e-41 140.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH47652.1 - 2.1e-12 46.7 0.0 4.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFH47652.1 - 4.7e-11 43.0 0.0 1.2e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KFH47652.1 - 0.00094 19.2 0.1 0.0082 16.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFH47652.1 - 0.0041 16.4 0.1 0.0075 15.5 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KFH47652.1 - 0.011 15.9 0.0 0.064 13.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFH47652.1 - 0.016 14.9 0.0 0.058 13.1 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH47652.1 - 0.017 15.5 0.3 0.57 10.5 0.1 2.9 2 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KFH47652.1 - 0.05 14.1 0.2 2.9 8.4 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFH47652.1 - 0.051 13.9 2.1 1.5 9.1 0.1 3.2 4 0 0 4 4 4 0 AAA domain Phage_TAC_10 PF10963.8 KFH47652.1 - 0.11 12.7 0.0 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone IstB_IS21 PF01695.17 KFH47652.1 - 0.13 12.0 0.1 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFH47652.1 - 0.15 12.2 0.1 0.58 10.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KFH47652.1 - 0.2 11.0 0.3 0.49 9.7 0.3 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 KFH47653.1 - 7.8e-57 192.0 0.2 1e-56 191.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFH47653.1 - 6.7e-25 87.6 0.0 1.6e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFH47653.1 - 2.8e-16 59.7 3.7 6.8e-16 58.4 3.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH47653.1 - 3.1e-05 24.0 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFH47653.1 - 0.0013 18.6 0.1 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KFH47653.1 - 0.024 14.2 0.4 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFH47653.1 - 0.06 13.1 0.2 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glycogen_syn PF05693.13 KFH47654.1 - 0 1170.6 0.0 0 1170.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KFH47654.1 - 3.6e-05 23.8 0.1 7.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KFH47654.1 - 5.8e-05 22.9 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFH47654.1 - 0.00017 21.2 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH47654.1 - 0.00045 20.6 0.0 0.45 10.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFH47654.1 - 0.00048 20.6 0.0 0.0015 19.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain MFAP1 PF06991.11 KFH47655.1 - 6.8e-69 232.0 29.8 6.8e-69 232.0 29.8 2.8 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Y2_Tnp PF04986.13 KFH47655.1 - 1.4 8.9 5.7 0.78 9.8 3.0 1.8 1 1 1 2 2 2 0 Putative transposase UPF0220 PF05255.11 KFH47656.1 - 1.4e-68 229.6 4.4 1.6e-68 229.5 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ECF_trnsprt PF12822.7 KFH47656.1 - 0.037 14.1 6.4 0.094 12.8 1.6 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component DUF410 PF04190.13 KFH47657.1 - 6.3e-91 304.7 0.0 7.7e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Thioredoxin PF00085.20 KFH47658.1 - 5.1e-58 193.4 0.0 5e-29 100.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KFH47658.1 - 3.9e-25 88.6 0.6 1.7e-24 86.5 0.4 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KFH47658.1 - 9.3e-20 71.1 0.1 9.9e-10 38.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFH47658.1 - 7.1e-15 55.1 0.0 2.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFH47658.1 - 4.1e-10 39.8 0.2 0.001 19.4 0.0 3.3 3 2 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KFH47658.1 - 9.8e-10 38.5 0.0 0.00028 21.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KFH47658.1 - 9.8e-09 35.2 0.0 0.0049 16.8 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KFH47658.1 - 1.5e-05 24.8 0.2 0.078 12.7 0.1 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 KFH47658.1 - 0.00013 22.0 0.1 0.69 9.8 0.0 2.9 2 1 1 3 3 3 3 Thioredoxin-like domain TraF PF13728.6 KFH47658.1 - 0.00016 21.6 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein ERp29_N PF07912.13 KFH47658.1 - 0.00035 20.7 0.6 0.034 14.3 0.0 3.1 3 0 0 3 3 3 1 ERp29, N-terminal domain HyaE PF07449.11 KFH47658.1 - 0.00055 19.9 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KFH47658.1 - 0.0017 18.5 1.2 1.9 8.8 0.0 3.2 2 2 0 2 2 2 2 Glutaredoxin Thioredoxin_9 PF14595.6 KFH47658.1 - 0.0026 17.5 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 KFH47658.1 - 0.0066 16.5 0.0 4 7.5 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KFH47658.1 - 0.01 16.0 2.1 1.2 9.3 0.1 2.9 2 2 0 3 3 3 0 Thioredoxin LAT PF15234.6 KFH47658.1 - 0.019 14.7 0.0 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells Flagellin_IN PF07196.13 KFH47658.1 - 1.5 9.0 4.8 12 6.2 0.0 3.2 3 0 0 3 3 3 0 Flagellin hook IN motif AMP-binding PF00501.28 KFH47659.1 - 8.3e-14 51.0 0.0 2.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme F-box-like PF12937.7 KFH47660.1 - 4.3e-06 26.5 0.2 8.8e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFH47660.1 - 0.055 13.9 2.4 26 5.4 0.0 4.5 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) Syntaxin-6_N PF09177.11 KFH47662.1 - 1.8e-28 99.0 3.1 4.2e-28 97.8 0.3 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KFH47662.1 - 0.00011 22.1 0.8 0.00032 20.6 0.8 1.8 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KFH47662.1 - 0.0046 16.7 0.3 0.0076 16.0 0.3 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 LPP PF04728.13 KFH47662.1 - 0.013 15.9 3.6 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SKA1 PF07160.12 KFH47662.1 - 0.027 14.3 0.4 0.99 9.2 0.2 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 LIF_OSM PF01291.17 KFH47662.1 - 0.21 11.7 2.1 0.53 10.4 0.3 2.2 2 1 0 2 2 2 0 LIF / OSM family CENP-Q PF13094.6 KFH47662.1 - 0.25 11.5 7.0 1.9 8.7 0.2 2.6 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 KFH47662.1 - 0.36 9.7 5.3 1.1 8.1 0.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KFH47662.1 - 0.57 10.0 5.4 1.2 8.9 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH RmuC PF02646.16 KFH47662.1 - 0.67 9.0 5.7 5.6 6.0 0.5 2.3 2 0 0 2 2 2 0 RmuC family Prefoldin_2 PF01920.20 KFH47662.1 - 1.2 9.1 5.7 13 5.8 0.8 2.9 2 1 0 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 KFH47662.1 - 1.4 9.2 5.0 1 9.6 0.3 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 KFH47662.1 - 2.9 8.1 14.0 1.7 8.9 3.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 KFH47662.1 - 4 7.1 8.4 2.9 7.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 KFH47662.1 - 6.4 7.3 7.6 14 6.2 0.5 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 KFH47662.1 - 8.7 6.7 9.9 17 5.7 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Sulfotransfer_4 PF17784.1 KFH47663.1 - 2.4e-61 207.3 0.0 2.8e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH47663.1 - 0.29 11.5 1.6 1.3 9.4 0.1 2.4 2 1 0 3 3 3 0 Sulfotransferase family Proteasome PF00227.26 KFH47664.1 - 4.4e-31 107.9 0.0 4.9e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 KFH47664.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) RNA_pol_L_2 PF13656.6 KFH47665.1 - 8.9e-22 76.7 0.1 1.1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFH47665.1 - 4.2e-07 29.3 0.0 1.2e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain E3_UbLigase_EDD PF11547.8 KFH47665.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD NPCC PF08058.11 KFH47667.1 - 1.8e-28 99.2 0.0 2.6e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component Glyco_hydro_43 PF04616.14 KFH47668.1 - 1.7e-23 83.4 0.0 2.8e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 ERG2_Sigma1R PF04622.12 KFH47669.1 - 1.1e-97 325.5 0.1 1.3e-97 325.3 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KFH47669.1 - 0.055 13.4 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_C48 PF02902.19 KFH47670.1 - 2.2e-33 115.9 0.0 4e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DNA_pol_A_exo1 PF01612.20 KFH47671.1 - 8.1e-17 61.5 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Ferritin_2 PF13668.6 KFH47672.1 - 6e-39 133.4 1.7 9.3e-39 132.7 1.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain Thymidylat_synt PF00303.19 KFH47673.1 - 2.9e-109 364.3 0.0 3.3e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase XRN_M PF17846.1 KFH47674.1 - 1.9e-98 330.3 2.8 3.1e-98 329.6 2.8 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFH47674.1 - 2.1e-97 325.3 0.0 3.9e-97 324.4 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFH47674.1 - 2.4e-69 232.9 0.6 3.6e-69 232.4 0.0 1.6 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KFH47674.1 - 6.6e-34 116.0 0.5 1.8e-33 114.6 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KFH47674.1 - 1.8e-20 72.8 0.2 3.5e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KFH47674.1 - 5.5e-06 26.4 0.1 1.2e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF2533 PF10752.9 KFH47674.1 - 0.019 15.4 0.1 0.072 13.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) zf-C2H2 PF00096.26 KFH47676.1 - 6.2e-16 57.9 25.4 0.00041 20.6 1.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH47676.1 - 7.2e-13 48.3 32.0 4.9e-09 36.2 2.1 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH47676.1 - 6.2e-08 32.8 21.4 0.019 15.7 0.7 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger Sialidase PF02973.16 KFH47676.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain zf-C2H2_8 PF15909.5 KFH47676.1 - 0.071 13.4 12.8 0.34 11.2 3.2 3.8 1 1 3 4 4 4 0 C2H2-type zinc ribbon C1_4 PF07975.12 KFH47676.1 - 0.073 13.3 0.5 0.073 13.3 0.5 2.4 2 1 0 2 2 2 0 TFIIH C1-like domain FOXP-CC PF16159.5 KFH47676.1 - 0.094 13.4 6.7 9.7 6.9 0.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFH47676.1 - 0.42 10.7 8.6 5.9 7.0 0.7 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 KFH47676.1 - 1.8 9.1 13.4 5.6 7.5 1.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ribosomal_S28e PF01200.18 KFH47677.1 - 6.7e-32 109.3 1.4 7.4e-32 109.1 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e CN_hydrolase PF00795.22 KFH47678.1 - 5.1e-16 58.8 0.0 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase MCM PF00493.23 KFH47680.1 - 8.3e-105 348.8 0.1 3.5e-104 346.8 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFH47680.1 - 4.7e-37 126.7 0.3 1.1e-36 125.4 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFH47680.1 - 4e-28 97.7 1.2 1.1e-27 96.3 1.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFH47680.1 - 1.5e-16 60.9 1.0 3.5e-16 59.7 1.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH47680.1 - 2e-06 27.4 0.0 0.00019 20.9 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFH47680.1 - 8.2e-06 25.9 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFH47680.1 - 0.00027 20.8 0.0 0.002 18.0 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFH47680.1 - 0.026 15.0 0.1 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFH47680.1 - 0.031 14.0 1.3 0.099 12.4 0.4 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFH47680.1 - 0.042 13.6 0.1 0.46 10.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFH47680.1 - 0.31 11.4 1.1 3.9 7.8 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain DER1 PF04511.15 KFH47681.1 - 1.8e-23 83.5 4.7 2.1e-23 83.3 4.7 1.0 1 0 0 1 1 1 1 Der1-like family SAC3_GANP PF03399.16 KFH47682.1 - 2.6e-93 312.6 0.0 4.7e-93 311.8 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP family COX5A PF02284.16 KFH47683.1 - 3.9e-41 139.2 0.2 5.4e-41 138.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4188 PF13826.6 KFH47684.1 - 9.2e-31 106.6 0.0 1.3e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KFH47684.1 - 0.038 13.4 0.3 0.12 11.8 0.3 1.6 1 1 0 1 1 1 0 Haem-containing dehydratase Rep_fac_C PF08542.11 KFH47686.1 - 4.8e-23 81.4 0.0 1.3e-22 80.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KFH47686.1 - 8.5e-12 45.1 0.0 1.4e-08 34.7 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KFH47686.1 - 1.9e-11 44.5 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFH47686.1 - 4.9e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH47686.1 - 1.8e-06 28.5 0.0 0.0001 22.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFH47686.1 - 4e-05 23.4 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFH47686.1 - 5.5e-05 23.5 0.1 0.17 12.2 0.0 2.6 2 1 1 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 KFH47686.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KFH47686.1 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFH47686.1 - 0.0035 16.7 0.0 0.028 13.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KFH47686.1 - 0.0045 16.8 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MeaB PF03308.16 KFH47686.1 - 0.0058 15.6 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 KFH47686.1 - 0.0071 16.7 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KFH47686.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFH47686.1 - 0.012 15.0 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 KFH47686.1 - 0.019 14.9 0.2 0.07 13.0 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 KFH47686.1 - 0.025 14.3 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFH47686.1 - 0.035 14.5 0.1 0.1 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 KFH47686.1 - 0.037 13.9 0.1 0.53 10.2 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DEAD PF00270.29 KFH47686.1 - 0.041 13.7 0.1 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase KTI12 PF08433.10 KFH47686.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 KFH47686.1 - 0.092 12.7 0.1 0.41 10.6 0.0 2.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DNA_ligase_A_M PF01068.21 KFH47687.1 - 2.2e-21 76.5 0.0 3.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFH47687.1 - 8.7e-18 65.2 0.0 1.7e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KFH47687.1 - 4.7e-05 23.7 0.0 8.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Aminotran_1_2 PF00155.21 KFH47688.1 - 3.7e-06 26.4 0.0 1.7e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II Proteasome PF00227.26 KFH47689.1 - 3.3e-55 186.5 0.1 4.4e-55 186.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFH47689.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature COPI_assoc PF08507.10 KFH47690.1 - 6.2e-30 103.9 9.7 7.5e-30 103.7 9.7 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2583 PF10762.9 KFH47690.1 - 0.26 11.7 3.2 0.65 10.5 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) Reticulon PF02453.17 KFH47691.1 - 2.8e-34 118.3 4.1 4e-34 117.8 4.1 1.2 1 0 0 1 1 1 1 Reticulon Prominin PF05478.11 KFH47691.1 - 0.065 11.2 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Prominin Wzy_C PF04932.15 KFH47691.1 - 0.12 12.0 0.9 0.41 10.3 0.0 2.1 2 1 0 2 2 2 0 O-Antigen ligase Methyltransf_8 PF05148.15 KFH47692.1 - 1.6e-58 198.1 0.0 2.4e-57 194.3 0.0 2.6 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KFH47692.1 - 2.6e-05 24.8 0.0 0.00011 22.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47692.1 - 0.0014 19.3 0.0 0.16 12.7 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFH47692.1 - 0.041 13.9 0.0 0.041 13.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_S64 PF08192.11 KFH47692.1 - 0.87 8.0 9.0 1.1 7.6 9.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC27 PF09507.10 KFH47692.1 - 1.9 7.8 34.4 3 7.1 34.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 KFH47692.1 - 4.2 6.0 13.3 6.3 5.5 13.3 1.3 1 0 0 1 1 1 0 Presenilin zf-CCHC_2 PF13696.6 KFH47693.1 - 3.2e-07 30.0 3.0 3.2e-07 30.0 3.0 2.6 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 KFH47693.1 - 0.15 12.5 0.3 0.15 12.5 0.3 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G MAGE_N PF12440.8 KFH47693.1 - 8.1 7.2 9.1 3.2 8.5 0.1 3.6 3 2 0 3 3 3 0 Melanoma associated antigen family N terminal Ysc84 PF04366.12 KFH47694.1 - 8.9e-28 96.6 0.0 1.5e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hexokinase_2 PF03727.16 KFH47695.1 - 2.5e-47 161.3 0.0 3.4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFH47695.1 - 3.1e-38 131.7 0.0 4.8e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Myb_DNA-binding PF00249.31 KFH47696.1 - 0.044 14.0 0.0 0.2 11.9 0.0 2.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Hid1 PF12722.7 KFH47696.1 - 1.2 7.2 4.0 1.8 6.6 4.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOG1_N PF17835.1 KFH47697.1 - 1e-49 168.6 0.1 1e-49 168.6 0.1 2.4 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KFH47697.1 - 4.1e-27 93.9 1.2 1.2e-26 92.4 1.2 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KFH47697.1 - 1.7e-26 91.7 0.3 4.6e-26 90.4 0.3 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KFH47697.1 - 3.8e-16 59.2 0.0 8.4e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFH47697.1 - 1.4e-08 34.5 0.4 3e-08 33.3 0.0 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFH47697.1 - 0.0021 18.2 0.0 1.8 8.6 0.0 2.9 1 1 0 2 2 2 2 Dynamin family Ras PF00071.22 KFH47697.1 - 0.0042 16.7 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFH47697.1 - 0.012 15.5 4.1 1.4 8.8 0.1 3.8 4 1 0 4 4 4 0 RsgA GTPase AAA_16 PF13191.6 KFH47697.1 - 0.017 15.5 1.7 0.19 12.1 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain MBR1 PF17058.5 KFH47697.1 - 0.025 14.9 3.5 0.056 13.7 3.5 1.6 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Roc PF08477.13 KFH47697.1 - 0.087 13.0 0.0 0.62 10.3 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFH47697.1 - 3.7 8.0 0.0 3.7 8.0 0.0 2.8 2 1 0 2 2 1 0 AAA domain Amidohydro_1 PF01979.20 KFH47698.1 - 1.2e-13 51.2 0.1 2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFH47698.1 - 0.0008 19.0 0.0 0.0029 17.2 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase family Linker_histone PF00538.19 KFH47698.1 - 0.09 13.2 0.2 16 6.0 0.0 2.7 2 0 0 2 2 2 0 linker histone H1 and H5 family Soyouz_module PF14313.6 KFH47698.1 - 0.099 12.4 1.0 14 5.5 0.0 3.4 2 1 1 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PDZ_1 PF12812.7 KFH47699.1 - 4.9e-54 180.3 0.0 8.6e-34 115.4 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KFH47699.1 - 1.8e-20 74.3 0.5 5.7e-19 69.5 0.2 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 KFH47699.1 - 1.1e-12 47.5 0.2 0.00051 19.8 0.1 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KFH47699.1 - 1.4e-12 47.7 0.2 0.0036 17.6 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 KFH47699.1 - 1.1e-06 28.9 0.0 0.023 15.0 0.0 3.8 3 0 0 3 3 3 2 PDZ domain 4HPAD_g_N PF18671.1 KFH47699.1 - 0.0042 16.7 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 KFH47699.1 - 0.018 15.0 0.4 23 5.0 0.1 4.1 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KFH47699.1 - 0.11 11.2 0.2 0.2 10.3 0.2 1.3 1 0 0 1 1 1 0 Peptidase S46 MFS_1 PF07690.16 KFH47700.1 - 5e-24 84.9 30.9 8.6e-14 51.2 26.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF5326 PF17260.2 KFH47700.1 - 0.07 13.3 0.6 0.07 13.3 0.6 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5326) OATP PF03137.20 KFH47700.1 - 0.33 9.2 6.2 0.05 11.9 1.1 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GCP_C_terminal PF04130.13 KFH47701.1 - 1.4e-79 267.8 0.0 3.4e-79 266.5 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFH47701.1 - 7.4e-28 98.1 0.0 1.4e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Focadhesin PF11229.8 KFH47701.1 - 0.062 11.5 0.1 0.095 10.9 0.1 1.2 1 0 0 1 1 1 0 Focadhesin Aldo_ket_red PF00248.21 KFH47702.1 - 1e-52 179.2 0.0 4.2e-52 177.2 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family MRP-L47 PF06984.13 KFH47703.1 - 2.8e-21 75.4 0.2 5.2e-21 74.6 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KFH47703.1 - 0.12 11.9 0.7 0.2 11.1 0.7 1.3 1 0 0 1 1 1 0 Clc-like NPR2 PF06218.11 KFH47704.1 - 6.7e-124 414.0 0.0 3.8e-101 339.0 0.0 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Myb_DNA-binding PF00249.31 KFH47705.1 - 0.044 14.0 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DTHCT PF08070.11 KFH47705.1 - 0.5 11.1 16.8 2.1 9.1 5.8 2.3 1 1 1 2 2 2 0 DTHCT (NUC029) region eIF-3c_N PF05470.12 KFH47705.1 - 2.8 6.2 6.1 3.4 5.9 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_Ag35 PF03286.14 KFH47705.1 - 5.5 6.7 13.3 14 5.4 13.3 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein SGL PF08450.12 KFH47706.1 - 5.2e-28 98.3 0.0 6.8e-28 97.9 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KFH47706.1 - 4.6e-05 23.4 0.0 0.00025 21.1 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KFH47706.1 - 0.00011 22.3 0.0 0.00081 19.5 0.0 2.3 2 0 0 2 2 2 1 Arylesterase FA_hydroxylase PF04116.13 KFH47707.1 - 1e-26 93.8 15.7 1e-26 93.8 15.7 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Lebercilin PF15619.6 KFH47708.1 - 0.54 9.9 3.6 5 6.7 0.0 2.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MFS_1 PF07690.16 KFH47709.1 - 1.3e-40 139.4 9.2 1.3e-40 139.4 9.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH47709.1 - 1.8e-09 37.0 1.6 1.8e-09 37.0 1.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 KFH47709.1 - 0.009 15.0 1.2 0.009 15.0 1.2 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_3 PF05977.13 KFH47709.1 - 2.5 6.4 7.2 1.5 7.1 1.4 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 KFH47711.1 - 1e-33 116.7 24.9 3.6e-27 95.2 5.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH47711.1 - 4.7e-08 32.3 6.8 4.7e-08 32.3 6.8 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFH47711.1 - 0.006 15.5 2.7 0.006 15.5 2.7 2.9 2 1 0 2 2 2 1 MFS_1 like family CUE PF02845.16 KFH47712.1 - 7.1e-10 38.4 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KFH47712.1 - 0.00038 20.4 1.8 0.00084 19.3 1.8 1.5 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 VIR_N PF15912.5 KFH47712.1 - 0.0015 18.2 4.1 0.0018 17.9 3.7 1.3 2 0 0 2 2 2 1 Virilizer, N-terminal DUF2205 PF10224.9 KFH47713.1 - 0.85 9.7 5.9 0.26 11.3 2.0 2.1 2 0 0 2 2 2 0 Short coiled-coil protein SNF2_N PF00176.23 KFH47714.1 - 3e-69 233.4 0.0 4.5e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFH47714.1 - 4.8e-19 68.1 0.0 1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFH47714.1 - 2.3e-14 53.7 0.0 5.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KFH47714.1 - 2.6e-08 33.6 9.1 2.6e-08 33.6 9.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH47714.1 - 9.8e-07 28.5 10.0 9.8e-07 28.5 10.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH47714.1 - 1.5e-06 28.1 9.7 4.1e-06 26.7 9.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFH47714.1 - 6.1e-06 26.0 9.4 1.9e-05 24.4 7.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH47714.1 - 4.7e-05 23.6 8.1 4.7e-05 23.6 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFH47714.1 - 0.00036 20.4 7.2 0.00083 19.3 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH47714.1 - 0.0031 17.4 9.1 0.0031 17.4 9.1 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFH47714.1 - 0.0033 17.7 4.3 0.0086 16.3 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFH47714.1 - 0.0059 16.7 7.8 0.013 15.7 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFH47714.1 - 0.006 16.4 1.7 0.015 15.2 1.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFH47714.1 - 0.089 12.9 1.8 0.2 11.7 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KFH47714.1 - 0.57 10.0 5.6 1.5 8.7 5.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFH47714.1 - 0.72 10.0 7.2 2.1 8.6 7.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_clus PF00172.18 KFH47715.1 - 4.8e-06 26.6 10.0 4.8e-06 26.6 10.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fez1 PF06818.15 KFH47716.1 - 0.00042 20.8 2.1 0.00071 20.1 2.1 1.3 1 0 0 1 1 1 1 Fez1 HMMR_N PF15905.5 KFH47716.1 - 0.00059 19.4 6.1 0.0011 18.6 6.1 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DASH_Spc34 PF08657.10 KFH47716.1 - 0.46 10.2 3.9 11 5.7 3.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 CREPT PF16566.5 KFH47716.1 - 0.53 10.4 5.0 1 9.6 0.1 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 KFH47716.1 - 1.1 8.6 6.8 0.14 11.5 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFH47716.1 - 6.6 7.1 10.0 0.36 11.2 3.9 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.6 KFH47716.1 - 9.1 5.6 14.8 4.3 6.6 1.1 2.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding UQ_con PF00179.26 KFH47717.1 - 1.2e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme tRNA-synt_1b PF00579.25 KFH47718.1 - 1.6e-71 241.0 0.0 2.4e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KFH47718.1 - 9e-44 148.1 0.0 1.7e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain HMG_box PF00505.19 KFH47719.1 - 1.4e-05 25.4 0.0 3.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFH47719.1 - 0.0028 18.2 0.4 0.0075 16.8 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain SLAC1 PF03595.17 KFH47720.1 - 1.4e-88 297.3 48.4 1.5e-88 297.2 48.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Sec62 PF03839.16 KFH47721.1 - 1.7e-67 227.1 4.9 1.7e-67 227.1 4.9 1.7 2 1 0 2 2 2 1 Translocation protein Sec62 DUF2207 PF09972.9 KFH47721.1 - 0.013 14.3 0.2 0.02 13.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) cobW PF02492.19 KFH47722.1 - 3.2e-48 163.7 0.3 4.1e-48 163.3 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFH47722.1 - 5.4e-06 26.4 0.1 0.094 12.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 KFH47722.1 - 0.0016 17.5 1.2 2.1 7.3 0.1 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFH47722.1 - 0.002 18.4 0.4 0.41 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 KFH47722.1 - 0.0028 17.2 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KFH47722.1 - 0.0033 17.9 0.2 0.012 16.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KFH47722.1 - 0.0062 16.4 0.2 0.7 9.6 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFH47722.1 - 0.0092 16.1 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFH47722.1 - 0.015 14.6 0.8 2.1 7.6 0.2 2.3 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFH47722.1 - 0.019 15.4 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KFH47722.1 - 0.029 14.1 0.9 0.46 10.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFH47722.1 - 0.039 13.7 0.4 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KFH47722.1 - 0.066 13.8 0.2 0.28 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFH47722.1 - 0.075 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KFH47722.1 - 0.64 9.0 2.8 0.28 10.2 0.3 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro_47 PF01532.20 KFH47723.1 - 4.5e-113 378.6 0.0 5.9e-113 378.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 p450 PF00067.22 KFH47724.1 - 9.2e-57 192.8 0.0 1.2e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Haem_oxygenas_2 PF14518.6 KFH47725.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Iron-containing redox enzyme Flavoprotein PF02441.19 KFH47726.1 - 2.8e-46 157.1 0.0 3.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.7 KFH47727.1 - 5e-23 81.5 0.0 3.1e-12 46.9 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFH47727.1 - 1.1e-18 66.7 0.5 5.9e-05 23.3 0.0 6.9 7 0 0 7 7 6 3 Ankyrin repeat Ank_3 PF13606.6 KFH47727.1 - 1.2e-16 59.1 0.2 0.00014 22.0 0.0 6.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFH47727.1 - 6.6e-16 58.5 0.1 1.5e-08 35.0 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH47727.1 - 1.6e-14 53.7 0.1 2.8e-08 33.9 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 KFH47727.1 - 3.2e-07 30.4 0.1 6.8e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFH47727.1 - 2.6e-05 24.7 0.1 6.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFH47727.1 - 0.019 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFH47727.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFH47727.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KFH47727.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KFH47727.1 - 0.17 11.0 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FNIP PF05725.12 KFH47727.1 - 0.2 11.8 0.0 0.61 10.3 0.0 1.8 2 0 0 2 2 2 0 FNIP Repeat MAS20 PF02064.15 KFH47728.1 - 5.1e-41 139.8 0.6 5.9e-41 139.6 0.6 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.12 KFH47728.1 - 0.0054 16.3 1.1 0.0067 16.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Rhabdo_ncap PF00945.18 KFH47728.1 - 0.018 13.9 0.3 0.022 13.6 0.3 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein AP-5_subunit_s1 PF15001.6 KFH47728.1 - 0.041 13.9 0.6 0.046 13.7 0.6 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4703 PF15775.5 KFH47728.1 - 2.2 8.0 5.2 3.3 7.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) RibD_C PF01872.17 KFH47730.1 - 1.4e-33 116.4 0.0 1.7e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain SH3_18 PF18354.1 KFH47730.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 CarS bacterial SH3 domain Fungal_trans PF04082.18 KFH47731.1 - 4.2e-13 48.9 0.4 1.4e-12 47.2 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFH47731.1 - 2e-06 28.0 7.8 1.8e-05 24.9 1.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KFH47731.1 - 0.00085 19.6 4.4 0.0016 18.7 4.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFH47731.1 - 0.0014 19.3 15.1 0.063 14.1 5.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH47731.1 - 0.4 11.2 14.6 0.37 11.3 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFH47731.1 - 1.8 8.9 6.8 8.8 6.7 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_76 PF03663.14 KFH47733.1 - 2.3e-54 185.3 11.3 2.7e-54 185.1 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFH47733.1 - 1.8e-07 30.5 4.0 0.00057 19.1 0.0 3.0 1 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFH47733.1 - 0.0036 15.9 1.0 1.1 7.6 0.0 2.3 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Bromodomain PF00439.25 KFH47735.1 - 2.2e-32 111.0 0.1 6.7e-17 61.3 0.1 2.6 2 0 0 2 2 2 2 Bromodomain ArAE_2_N PF10337.9 KFH47736.1 - 1.6e-11 43.9 19.6 1.3e-05 24.5 5.9 3.6 2 2 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KFH47736.1 - 5.5e-10 39.4 19.7 5.5e-10 39.4 19.7 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KFH47736.1 - 3.3e-05 22.9 21.2 0.0033 16.3 17.6 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter Ribosomal_60s PF00428.19 KFH47736.1 - 0.088 13.4 2.2 23 5.7 3.8 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4407 PF14362.6 KFH47736.1 - 1.2 8.4 6.5 1.9 7.8 4.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Hydrolase PF00702.26 KFH47737.1 - 2.5e-08 34.5 0.0 2.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFH47737.1 - 5.1e-08 33.2 0.0 6.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH47737.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DASH_Dad4 PF08650.10 KFH47738.1 - 9.3e-16 57.6 1.5 1e-15 57.5 1.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 tRNA-synt_2b PF00587.25 KFH47739.1 - 4.1e-32 111.6 0.1 1.3e-28 100.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFH47739.1 - 1.6e-08 34.6 0.0 3.8e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Anticodon binding domain Cytomega_UL20A PF05984.12 KFH47739.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Hemerythrin PF01814.23 KFH47740.1 - 4.8e-09 36.9 0.6 6.8e-09 36.4 0.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TAP42 PF04177.12 KFH47741.1 - 1.3e-95 320.2 0.0 1.5e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.8 KFH47741.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 KIF-1 binding protein C terminal Actin PF00022.19 KFH47742.1 - 7.9e-17 61.0 0.0 8.2e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 Actin Spem1 PF15670.5 KFH47744.1 - 0.11 12.1 10.3 0.14 11.7 10.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Syndecan PF01034.20 KFH47744.1 - 0.11 12.4 0.9 0.18 11.7 0.9 1.2 1 0 0 1 1 1 0 Syndecan domain Ctr PF04145.15 KFH47744.1 - 0.22 12.1 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family WD40 PF00400.32 KFH47745.1 - 5.1e-18 65.1 9.2 0.00078 20.2 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH47745.1 - 0.0033 17.7 0.1 2.7 8.4 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3258 PF11646.8 KFH47745.1 - 0.19 11.9 0.0 0.72 10.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF3258 Got1 PF04178.12 KFH47746.1 - 1.4e-14 54.4 12.7 1.9e-14 54.1 12.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Methyltransf_11 PF08241.12 KFH47747.1 - 6.7e-06 26.7 0.0 9.3e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47747.1 - 2.7e-05 24.8 0.0 6.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47747.1 - 0.054 14.2 0.0 0.12 13.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain CybS PF05328.12 KFH47748.1 - 3.8e-46 156.1 0.0 4.8e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 KFH47748.1 - 0.054 13.5 0.9 0.49 10.5 0.8 2.0 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Kinesin PF00225.23 KFH47749.1 - 1.5e-113 379.1 0.4 4.2e-113 377.7 0.4 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFH47749.1 - 5.5e-27 94.5 0.1 2.4e-26 92.5 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 KFH47749.1 - 0.011 16.0 15.8 0.011 16.0 15.8 3.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) TetR_C_31 PF17940.1 KFH47749.1 - 0.43 10.8 2.2 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LURAP PF14854.6 KFH47749.1 - 1.7 8.6 8.4 5.4 7.0 0.7 3.3 3 0 0 3 3 3 0 Leucine rich adaptor protein CENP-F_leu_zip PF10473.9 KFH47749.1 - 3.8 7.5 69.4 5.5 7.0 24.7 5.0 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH PF00169.29 KFH47750.1 - 0.096 13.2 0.0 0.21 12.1 0.0 1.6 1 1 0 1 1 1 0 PH domain MscL PF01741.18 KFH47751.1 - 9.7e-20 71.1 0.2 1.2e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 KFH47751.1 - 0.012 15.5 1.7 0.021 14.7 1.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4690 PF15756.5 KFH47754.1 - 4.1e-05 24.1 0.1 0.00016 22.2 0.1 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SH3_9 PF14604.6 KFH47754.1 - 6.4e-05 22.7 0.2 0.00013 21.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFH47754.1 - 0.00048 19.7 0.1 0.00096 18.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 KFH47754.1 - 0.0027 17.8 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 KFH47754.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A DUF1803 PF08820.10 KFH47754.1 - 0.041 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) DAP10 PF07213.11 KFH47754.1 - 0.33 11.0 1.4 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 DAP10 membrane protein PLDc_2 PF13091.6 KFH47755.1 - 5.4e-16 58.7 0.0 2.4e-06 27.5 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KFH47755.1 - 1.5e-14 53.5 0.2 2e-06 27.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif TFIID-18kDa PF02269.16 KFH47756.1 - 1.2e-26 92.6 2.7 1.4e-26 92.3 0.2 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit SUR7 PF06687.12 KFH47757.1 - 1.2e-25 90.5 0.0 1.4e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KFH47757.1 - 0.00011 22.1 4.3 0.00023 21.1 4.3 1.5 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF5134 PF17197.4 KFH47757.1 - 0.0014 18.5 1.6 0.0027 17.6 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) Acyl_transf_3 PF01757.22 KFH47757.1 - 0.25 10.4 4.7 0.079 12.0 1.8 1.5 2 0 0 2 2 2 0 Acyltransferase family DUF5362 PF17319.2 KFH47757.1 - 0.38 10.6 5.1 1.5 8.7 0.0 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5362) DUF2157 PF09925.9 KFH47757.1 - 4.5 7.0 9.6 1 9.1 4.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ank_2 PF12796.7 KFH47758.1 - 9.8e-57 189.5 0.0 1.8e-10 41.3 0.2 7.3 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH47758.1 - 7.3e-46 154.0 0.1 4.9e-06 27.0 0.0 11.3 7 4 6 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFH47758.1 - 8.7e-41 137.5 4.4 5.7e-06 26.5 0.0 10.0 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH47758.1 - 2.7e-40 131.7 2.1 0.0047 17.3 0.0 14.7 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 KFH47758.1 - 1.1e-34 117.3 6.6 0.014 15.9 0.0 14.2 14 1 1 15 15 15 10 Ankyrin repeat Sec63 PF02889.16 KFH47759.1 - 1.6e-136 453.5 0.0 6e-80 268.1 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFH47759.1 - 2.1e-51 174.2 0.3 8.7e-27 94.0 0.2 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KFH47759.1 - 7.7e-22 78.1 0.0 1.1e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH47759.1 - 1.8e-16 60.4 0.5 1.2e-06 28.9 0.0 4.7 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFH47759.1 - 7.1e-08 32.8 0.0 0.016 15.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFH47759.1 - 1.8e-06 28.3 0.5 0.00066 20.0 0.4 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFH47759.1 - 2.6e-06 27.3 0.1 0.018 14.8 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KFH47759.1 - 0.0017 18.7 0.1 2.4 8.6 0.0 4.3 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFH47759.1 - 0.029 13.5 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KFH47759.1 - 0.074 12.5 0.3 20 4.5 0.1 3.6 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 KFH47759.1 - 0.11 11.9 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SMC_N PF02463.19 KFH47760.1 - 4.7e-67 225.6 18.6 3.1e-65 219.7 18.6 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFH47760.1 - 2.6e-20 72.9 0.5 2.6e-20 72.9 0.5 3.1 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFH47760.1 - 7.5e-11 42.4 5.4 0.00017 21.5 0.1 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MscS_porin PF12795.7 KFH47760.1 - 1.7e-06 27.7 32.9 1.7e-06 27.7 32.9 5.8 2 2 2 5 5 5 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.6 KFH47760.1 - 0.00011 21.9 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tup_N PF08581.10 KFH47760.1 - 0.0032 17.7 4.1 0.0032 17.7 4.1 8.3 5 4 3 8 8 8 1 Tup N-terminal HSBP1 PF06825.12 KFH47760.1 - 0.02 14.7 16.5 0.066 13.1 0.7 4.2 4 0 0 4 4 4 0 Heat shock factor binding protein 1 YbbR PF07949.12 KFH47760.1 - 0.024 14.9 0.2 0.37 11.1 0.0 3.1 2 0 0 2 2 2 0 YbbR-like protein ABC_tran PF00005.27 KFH47760.1 - 0.047 14.2 0.0 0.047 14.2 0.0 5.9 4 2 0 4 4 4 0 ABC transporter DNA_topoisoIV PF00521.20 KFH47761.1 - 1.9e-118 396.0 0.4 4.3e-118 394.9 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFH47761.1 - 2.4e-48 163.6 3.3 2.4e-48 163.6 3.3 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFH47761.1 - 5e-25 88.0 2.1 1.1e-24 86.9 2.1 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFH47761.1 - 8.6e-13 48.8 0.1 2e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFH47761.1 - 1.5e-06 28.3 0.2 1.3e-05 25.4 0.0 2.8 3 0 0 3 3 3 1 Toprim domain HATPase_c_3 PF13589.6 KFH47761.1 - 0.1 12.4 1.1 0.3 10.9 0.3 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3112 PF11309.8 KFH47762.1 - 4.2e-12 46.0 7.2 5.3e-09 35.9 0.0 2.7 2 2 0 3 3 3 2 Protein of unknown function (DUF3112) MIG-14_Wnt-bd PF06664.12 KFH47762.1 - 0.48 9.6 12.1 0.3 10.3 7.9 2.1 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion MFS_Mycoplasma PF07672.13 KFH47762.1 - 4.4 6.5 10.8 0.28 10.4 5.4 1.6 2 0 0 2 2 2 0 Mycoplasma MFS transporter SUN PF03856.13 KFH47763.1 - 2.7e-77 259.5 8.7 3.5e-77 259.2 8.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF572 PF04502.13 KFH47763.1 - 1 9.0 6.9 1.4 8.4 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 KFH47763.1 - 8.9 5.8 7.0 13 5.3 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DAO PF01266.24 KFH47764.1 - 9e-63 213.0 5.6 1e-62 212.8 5.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH47764.1 - 1.1e-05 25.6 0.6 2.6e-05 24.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KFH47764.1 - 0.00061 18.5 0.1 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 KFH47764.1 - 0.00064 19.2 0.8 0.0033 16.8 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH47764.1 - 0.00077 18.8 0.4 0.0016 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KFH47764.1 - 0.0048 16.2 0.4 0.027 13.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFH47764.1 - 0.13 12.6 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pribosyltran PF00156.27 KFH47765.1 - 9e-17 61.0 0.8 1.4e-16 60.5 0.8 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFH47765.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Myb_Cef PF11831.8 KFH47766.1 - 1.1e-48 166.0 8.0 1.1e-48 166.0 8.0 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFH47766.1 - 1.1e-22 79.9 4.8 8.8e-11 41.8 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH47766.1 - 1.7e-20 73.0 7.9 7.6e-15 54.9 3.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Golgin_A5 PF09787.9 KFH47766.1 - 0.0017 17.9 4.0 0.0017 17.9 4.0 2.4 3 0 0 3 3 3 1 Golgin subfamily A member 5 Rap1_C PF11626.8 KFH47766.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.1 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Thiolase_N PF00108.23 KFH47768.1 - 1.6e-87 293.2 0.5 2.6e-87 292.5 0.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFH47768.1 - 1.5e-38 131.2 1.2 1.5e-38 131.2 1.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFH47768.1 - 6.9e-06 25.8 3.4 1.5e-05 24.7 1.7 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFH47768.1 - 1.3 9.0 4.5 13 5.8 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HSP70 PF00012.20 KFH47769.1 - 1e-267 889.2 16.2 1.2e-267 889.0 16.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFH47769.1 - 3.7e-14 52.3 5.7 2.6e-12 46.2 2.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFH47769.1 - 0.00014 21.7 0.1 0.00048 19.9 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SMBP PF16785.5 KFH47769.1 - 0.049 13.9 4.9 0.13 12.4 4.9 1.8 1 0 0 1 1 1 0 Small metal-binding protein Med9 PF07544.13 KFH47769.1 - 0.8 9.8 3.4 19 5.4 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GCP_N_terminal PF17681.1 KFH47770.1 - 1.5e-62 212.0 0.0 3.1e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFH47770.1 - 8.9e-62 209.3 0.7 8.9e-62 209.3 0.7 2.1 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal TT_ORF2 PF02957.15 KFH47770.1 - 0.14 13.1 0.1 0.14 13.1 0.1 2.5 3 0 0 3 3 3 0 TT viral ORF2 Exo84_C PF16528.5 KFH47771.1 - 2.7e-78 262.5 0.2 2.7e-78 262.5 0.2 2.5 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KFH47771.1 - 3.3e-16 59.1 2.4 1.3e-15 57.3 2.4 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KFH47771.1 - 0.0022 18.1 0.3 0.16 12.0 0.0 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KFH47771.1 - 0.12 10.4 4.4 0.063 11.2 0.3 2.0 2 0 0 2 2 2 0 Prominin DUF2383 PF09537.10 KFH47771.1 - 0.47 10.8 4.5 16 5.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF4407 PF14362.6 KFH47771.1 - 1.8 7.9 8.8 11 5.2 8.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ada3 PF10198.9 KFH47772.1 - 1.5e-52 177.2 1.8 1.6e-52 177.1 0.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Ribosomal_60s PF00428.19 KFH47772.1 - 0.66 10.6 5.3 2.6 8.7 5.3 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DASH_Ask1 PF08655.10 KFH47773.1 - 5.2e-20 71.1 0.0 1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Fungal_trans_2 PF11951.8 KFH47774.1 - 5.2e-16 58.4 1.5 4.5e-09 35.6 0.2 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47774.1 - 5e-08 32.9 11.6 8.5e-08 32.2 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH47774.1 - 0.097 11.7 0.1 0.3 10.1 0.1 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Ist1 PF03398.14 KFH47775.1 - 2.2e-60 203.3 0.7 2.9e-60 202.9 0.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1479 PF07350.12 KFH47776.1 - 7.2e-165 548.8 0.0 8.4e-165 548.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KFH47776.1 - 0.019 15.2 0.3 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) GTP_EFTU PF00009.27 KFH47777.1 - 4.9e-52 176.3 0.0 8.1e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFH47777.1 - 4.6e-20 71.5 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFH47777.1 - 8.5e-13 48.2 0.0 6.9e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFH47777.1 - 2.6e-05 24.5 0.0 0.00011 22.5 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF615 PF04751.14 KFH47777.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF615) zf-RING_2 PF13639.6 KFH47778.1 - 3.8e-09 36.7 7.5 6.4e-09 36.0 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFH47778.1 - 3.2e-06 26.9 6.4 5.7e-06 26.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH47778.1 - 2.1e-05 24.1 7.5 2.1e-05 24.1 7.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFH47778.1 - 0.00015 21.5 6.4 0.00026 20.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH47778.1 - 0.00022 21.4 5.0 0.00074 19.8 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFH47778.1 - 0.00062 19.7 6.9 0.001 19.0 6.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFH47778.1 - 0.0063 16.1 5.3 0.014 15.0 5.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KFH47778.1 - 0.0092 16.0 6.5 0.029 14.4 6.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFH47778.1 - 0.014 15.4 3.3 0.029 14.4 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.9 KFH47778.1 - 0.18 12.3 0.1 0.18 12.3 0.1 1.7 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 LapA_dom PF06305.11 KFH47778.1 - 0.24 11.3 4.5 0.1 12.4 1.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3955 PF13127.6 KFH47778.1 - 0.28 11.0 2.5 0.45 10.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Prok-RING_4 PF14447.6 KFH47778.1 - 0.39 10.6 9.3 0.77 9.7 9.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFH47778.1 - 0.48 10.3 9.0 0.82 9.6 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFH47778.1 - 5.6 7.2 9.0 10 6.3 9.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RIBIOP_C PF04950.12 KFH47779.1 - 6.2e-93 311.4 0.1 6.2e-93 311.4 0.1 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFH47779.1 - 5e-29 100.2 0.0 3.4e-28 97.6 0.0 2.5 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KFH47779.1 - 2.9e-05 24.3 0.0 0.00012 22.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH47779.1 - 3.3e-05 24.4 0.0 0.00019 21.8 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KFH47779.1 - 0.0002 21.0 0.0 0.059 12.9 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFH47779.1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KFH47779.1 - 0.00055 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KFH47779.1 - 0.00071 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFH47779.1 - 0.00078 20.0 0.0 0.00078 20.0 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_33 PF13671.6 KFH47779.1 - 0.00095 19.3 1.0 0.0032 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFH47779.1 - 0.0049 17.2 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH47779.1 - 0.007 16.1 0.2 0.029 14.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KFH47779.1 - 0.0086 15.3 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KFH47779.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 KFH47779.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KFH47779.1 - 0.016 15.1 0.3 0.42 10.5 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KFH47779.1 - 0.018 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KFH47779.1 - 0.019 15.0 0.0 0.062 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KFH47779.1 - 0.024 14.5 0.4 0.5 10.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 KFH47779.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 KFH47779.1 - 0.035 14.0 0.2 0.073 13.0 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KFH47779.1 - 0.035 14.7 0.0 0.035 14.7 0.0 4.3 5 1 0 5 5 3 0 AAA domain RsgA_GTPase PF03193.16 KFH47779.1 - 0.036 14.0 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KFH47779.1 - 0.037 14.3 0.0 0.037 14.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KFH47779.1 - 0.04 13.7 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain pXO2-72 PF17443.2 KFH47779.1 - 0.042 14.1 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 Rad17 PF03215.15 KFH47779.1 - 0.045 13.7 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KFH47779.1 - 0.046 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFH47779.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KFH47779.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFH47779.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KFH47779.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KFH47779.1 - 0.15 12.0 0.0 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Asp_protease PF09668.10 KFH47780.1 - 2.9e-58 195.1 0.2 4.3e-58 194.5 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFH47780.1 - 8.8e-23 80.7 0.1 2.8e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFH47780.1 - 5.3e-11 43.0 0.0 1.5e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 KFH47780.1 - 2e-09 37.1 0.1 4.1e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFH47780.1 - 1.2e-08 34.7 0.5 2.8e-08 33.5 0.5 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 KFH47780.1 - 0.00015 22.0 0.1 0.00093 19.5 0.0 2.4 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.11 KFH47780.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KFH47780.1 - 0.0011 18.7 0.1 0.0032 17.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 KFH47780.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain bZIP_1 PF00170.21 KFH47781.1 - 6.4e-08 32.6 9.8 1.4e-07 31.5 9.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF5094 PF17015.5 KFH47781.1 - 1.3 9.1 5.0 0.21 11.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) FPN1 PF06963.12 KFH47782.1 - 1.1e-112 376.8 16.4 1.2e-112 376.6 16.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Tyr-DNA_phospho PF06087.12 KFH47783.1 - 1.5e-158 528.1 0.0 1.8e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KFH47783.1 - 0.013 15.3 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Het-C PF07217.11 KFH47784.1 - 1.1e-235 783.5 0.0 1.4e-235 783.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pox_VLTF3 PF04947.14 KFH47784.1 - 0.026 14.2 0.1 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like ResIII PF04851.15 KFH47785.1 - 2.4e-27 96.0 0.0 5.3e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH47785.1 - 1.6e-15 57.4 0.4 2.2e-14 53.7 0.0 2.8 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFH47785.1 - 3.8e-11 43.1 0.0 8.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFH47785.1 - 2.4e-06 27.4 0.0 5.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KFH47785.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KFH47785.1 - 0.012 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 KFH47785.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Protamine_like PF06382.11 KFH47785.1 - 0.038 14.2 0.3 0.69 10.1 0.2 2.3 2 0 0 2 2 2 0 Protamine and protamine like DUF3072 PF11272.8 KFH47785.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) GDI PF00996.18 KFH47786.1 - 2.3e-191 636.0 0.0 2.6e-191 635.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KFH47786.1 - 0.037 14.2 0.1 0.09 13.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH47786.1 - 0.14 12.8 0.1 0.59 10.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DnaJ PF00226.31 KFH47787.1 - 7.8e-22 77.2 1.3 1.5e-21 76.3 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain HIT PF01230.23 KFH47788.1 - 1.4e-17 64.3 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 KFH47788.1 - 0.012 15.5 0.4 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 KFH47788.1 - 0.049 14.1 0.0 0.074 13.5 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Eaf7 PF07904.13 KFH47790.1 - 4.1e-27 94.7 0.2 4.1e-27 94.7 0.2 1.7 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 AlkA_N PF06029.11 KFH47790.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 AlkA N-terminal domain SRP-alpha_N PF04086.13 KFH47790.1 - 4.9 7.0 12.9 8.3 6.2 12.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPP4R2 PF09184.11 KFH47790.1 - 6.7 6.2 9.4 10 5.6 9.4 1.3 1 0 0 1 1 1 0 PPP4R2 NOT2_3_5 PF04153.18 KFH47791.1 - 1.4e-22 80.2 5.2 2.4e-11 43.8 3.0 2.3 2 0 0 2 2 2 2 NOT2 / NOT3 / NOT5 family TPR_2 PF07719.17 KFH47792.1 - 5.7e-07 29.2 4.5 0.34 11.2 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFH47792.1 - 5.9e-06 25.9 3.7 0.85 9.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFH47792.1 - 0.00065 20.2 0.9 0.00065 20.2 0.9 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH47792.1 - 0.0075 16.5 1.1 0.017 15.3 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFH47792.1 - 0.034 14.3 2.9 2.4 8.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH47792.1 - 1.1 10.3 9.1 1.7 9.6 0.4 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.20 KFH47794.1 - 1.7e-56 190.1 1.6 1.9e-56 189.9 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pterin_4a PF01329.19 KFH47795.1 - 7.9e-26 90.1 0.7 2.9e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Fungal_trans PF04082.18 KFH47796.1 - 2.4e-32 112.0 0.0 6e-32 110.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH47796.1 - 4.7e-09 36.2 9.3 7.6e-09 35.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArAE_1_C PF11728.8 KFH47796.1 - 0.25 11.3 0.9 1.7 8.6 0.2 2.1 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Ribonuclease_T2 PF00445.18 KFH47797.1 - 2.1e-31 109.6 0.1 3.4e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family NCA2 PF08637.10 KFH47798.1 - 1.3e-108 362.6 0.0 2e-108 362.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 KFH47798.1 - 0.042 12.8 0.1 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Myb_DNA-bind_3 PF12776.7 KFH47799.1 - 0.0074 17.3 1.2 0.016 16.2 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1459 PF07312.11 KFH47799.1 - 1.3 9.3 6.9 10 6.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Ccdc124 PF06244.12 KFH47800.1 - 7.8e-28 97.6 21.9 2e-26 93.1 21.9 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF5539 PF17693.1 KFH47800.1 - 2.9 7.5 5.8 0.64 9.6 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5539) Fungal_trans_2 PF11951.8 KFH47801.1 - 1.2e-05 24.4 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KFH47802.1 - 2.5e-09 36.5 0.0 4.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DASH_Dam1 PF08653.10 KFH47803.1 - 0.075 12.9 0.2 0.54 10.1 0.0 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 CDO_I PF05995.12 KFH47804.1 - 1e-43 148.6 0.0 1.2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFH47804.1 - 0.022 14.2 0.2 0.045 13.2 0.2 1.7 1 1 0 1 1 1 0 PCO_ADO Mob1_phocein PF03637.17 KFH47805.1 - 1.5e-22 80.4 0.1 2.2e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KFH47805.1 - 0.036 14.3 3.9 0.09 13.1 3.9 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Pribosyltran PF00156.27 KFH47806.1 - 6.3e-17 61.5 0.0 9.2e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFH47806.1 - 0.00043 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CD52 PF15116.6 KFH47806.1 - 0.14 12.2 4.7 0.31 11.1 4.7 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen Semialdhyde_dh PF01118.24 KFH47807.1 - 3.5e-30 104.9 0.1 9.5e-30 103.5 0.0 1.8 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KFH47807.1 - 5.5e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain NAD_binding_10 PF13460.6 KFH47807.1 - 0.022 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 KFH47807.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KFH47807.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PfkB PF00294.24 KFH47808.1 - 6.4e-54 183.3 0.0 8.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PCI PF01399.27 KFH47809.1 - 0.0015 19.0 0.0 3 8.4 0.0 3.0 3 0 0 3 3 3 2 PCI domain TetR_C_20 PF17925.1 KFH47809.1 - 0.013 15.7 0.4 0.045 14.1 0.4 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IBN_N PF03810.19 KFH47811.1 - 8.6e-14 51.2 0.2 9.1e-13 47.9 0.0 2.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFH47811.1 - 0.00048 20.2 0.5 0.0052 16.9 0.1 2.9 3 0 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.10 KFH47811.1 - 0.0012 17.7 0.2 0.022 13.6 0.0 2.2 2 0 0 2 2 2 1 Cse1 DUF3385 PF11865.8 KFH47811.1 - 0.25 11.2 2.4 0.93 9.4 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Wyosine_form PF08608.12 KFH47813.1 - 2.8e-24 85.2 0.0 6.5e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KFH47813.1 - 2.2e-23 83.5 0.1 6.4e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KFH47813.1 - 3.5e-09 37.0 0.8 1.7e-06 28.3 0.0 3.5 2 1 0 3 3 3 1 Flavodoxin Transp_cyt_pur PF02133.15 KFH47815.1 - 1.6e-27 96.4 35.1 2.9e-26 92.2 35.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_76 PF03663.14 KFH47816.1 - 4.8e-131 437.6 3.2 5.4e-131 437.4 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFH47816.1 - 0.00033 19.8 3.2 0.3 10.1 0.1 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFH47816.1 - 0.0028 16.2 0.1 0.16 10.4 0.0 2.3 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 KFH47816.1 - 0.18 11.0 4.1 0.68 9.1 1.4 2.3 1 1 1 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Aminotran_1_2 PF00155.21 KFH47817.1 - 9.9e-64 215.8 0.0 1.2e-63 215.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFH47817.1 - 0.056 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Allinase Med21 PF11221.8 KFH47818.1 - 9.6e-45 152.4 7.9 1.1e-44 152.2 7.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex CtIP_N PF10482.9 KFH47818.1 - 0.002 18.2 2.6 0.023 14.7 0.7 2.2 1 1 1 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 KFH47818.1 - 0.0022 17.4 5.9 0.048 13.0 0.1 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4226 PF10774.9 KFH47818.1 - 0.014 15.7 4.9 1.4 9.3 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Mei5 PF10376.9 KFH47818.1 - 0.019 14.8 1.9 0.021 14.7 1.9 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein Med9 PF07544.13 KFH47818.1 - 0.028 14.5 1.5 0.028 14.5 1.5 2.6 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 KFH47818.1 - 0.062 13.5 3.6 0.08 13.1 1.6 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RACo_linker PF17650.1 KFH47818.1 - 0.064 13.1 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 RACo linker region HMMR_N PF15905.5 KFH47818.1 - 0.14 11.6 7.6 0.11 12.0 5.4 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TraB PF01963.17 KFH47818.1 - 0.2 11.5 3.1 0.21 11.4 2.4 1.3 1 1 0 1 1 1 0 TraB family DUF2841 PF11001.8 KFH47818.1 - 0.22 11.6 1.9 0.26 11.3 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2841) Peptidase_M16 PF00675.20 KFH47818.1 - 0.35 10.8 2.3 2.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF16 PF01519.16 KFH47818.1 - 0.47 11.0 3.8 0.67 10.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 KFH47818.1 - 0.55 10.8 10.5 1.5 9.3 10.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region AHSP PF09236.10 KFH47818.1 - 0.78 10.2 4.0 1.6 9.2 1.0 2.7 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein Maf PF02545.14 KFH47819.1 - 1.4e-47 161.6 0.0 1.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ubiquitin PF00240.23 KFH47820.1 - 2e-19 69.1 0.0 3.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFH47820.1 - 2.9e-07 30.2 0.1 2.9e-07 30.2 0.1 3.0 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFH47820.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFH47820.1 - 3e-05 24.1 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFH47820.1 - 0.0045 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GET2 PF08690.10 KFH47820.1 - 0.01 15.6 2.9 0.01 15.6 2.9 2.9 2 1 0 2 2 2 0 GET complex subunit GET2 HOIP-UBA PF16678.5 KFH47820.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_2 PF14560.6 KFH47820.1 - 0.16 12.4 0.2 0.75 10.3 0.2 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KFH47820.1 - 0.43 10.5 11.2 0.26 11.2 6.7 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain MatE PF01554.18 KFH47821.1 - 5.6e-55 185.4 28.1 1.5e-32 112.4 12.0 2.4 2 0 0 2 2 2 2 MatE RabGAP-TBC PF00566.18 KFH47822.1 - 5.8e-49 166.7 0.0 1.7e-48 165.1 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1664 PF07889.12 KFH47822.1 - 0.0055 16.7 5.2 0.0055 16.7 5.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) BST2 PF16716.5 KFH47822.1 - 0.013 16.0 6.3 0.013 16.0 6.3 3.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Psu PF07455.11 KFH47822.1 - 0.016 14.8 1.5 2.4 7.7 0.1 2.9 3 0 0 3 3 3 0 Phage polarity suppression protein (Psu) Laminin_II PF06009.12 KFH47822.1 - 1.9 8.5 11.9 0.062 13.3 4.2 2.4 2 0 0 2 2 2 0 Laminin Domain II APG6_N PF17675.1 KFH47822.1 - 7.1 7.2 39.4 0.15 12.6 13.0 4.6 3 1 1 4 4 4 0 Apg6 coiled-coil region AHL_synthase PF17327.2 KFH47823.1 - 0.27 10.2 0.0 0.39 9.7 0.0 1.1 1 0 0 1 1 1 0 Acyl homoserine lactone synthase Zn_clus PF00172.18 KFH47824.1 - 6.6e-07 29.3 10.4 1.2e-06 28.6 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH47824.1 - 0.00018 20.4 0.4 0.00018 20.4 0.4 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain SR-25 PF10500.9 KFH47824.1 - 0.16 11.6 3.7 0.24 11.0 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KFH47824.1 - 0.4 11.4 4.3 0.77 10.5 4.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Actin PF00022.19 KFH47825.1 - 6.5e-49 166.6 0.0 7e-24 84.2 0.0 3.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFH47825.1 - 0.039 12.8 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein HLH PF00010.26 KFH47826.1 - 2.4e-06 27.4 0.2 4e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyoxalase PF00903.25 KFH47826.1 - 0.039 14.2 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KFH47827.1 - 1.2e-24 87.2 0.8 2e-16 60.2 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH47827.1 - 7.4e-07 29.3 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFH47827.1 - 8.7e-05 21.8 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFH47827.1 - 9.3e-05 21.8 0.0 0.0076 15.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH47827.1 - 0.00029 20.5 0.1 0.0028 17.3 0.0 2.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFH47827.1 - 0.0011 18.0 0.1 0.072 12.1 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KFH47827.1 - 0.0073 15.6 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KFH47827.1 - 0.0081 14.9 0.0 0.016 13.9 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KFH47827.1 - 0.036 14.6 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH47827.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KFH47827.1 - 0.19 11.4 0.0 0.75 9.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFH47827.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UQ_con PF00179.26 KFH47828.1 - 1.6e-52 176.9 0.1 1.8e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH47828.1 - 0.00083 19.1 0.0 0.00092 18.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFH47828.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.4 1 1 0 1 1 1 0 RWD domain DcpS PF05652.12 KFH47830.1 - 2.6e-36 124.6 0.0 4e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KFH47830.1 - 1.1e-29 103.2 0.0 1.8e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding 2OG-FeII_Oxy_2 PF13532.6 KFH47831.1 - 1.6e-35 123.1 0.0 2.1e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KFH47831.1 - 1.5e-09 37.8 6.5 2.9e-09 36.9 6.5 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KFH47831.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 CUE domain YL1_C PF08265.11 KFH47832.1 - 3.1e-15 55.6 0.1 4.9e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain p450 PF00067.22 KFH47833.1 - 1e-55 189.3 0.0 1.4e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LCM PF04072.14 KFH47835.1 - 3.2e-20 72.9 0.0 2.5e-19 69.9 0.0 2.3 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SlyX PF04102.12 KFH47836.1 - 0.0037 17.8 4.3 0.55 10.9 1.8 2.4 2 0 0 2 2 2 2 SlyX PriC PF07445.12 KFH47836.1 - 0.0046 16.9 0.6 0.0068 16.3 0.6 1.3 1 0 0 1 1 1 1 Primosomal replication protein priC Asparaginase_II PF06089.12 KFH47836.1 - 0.29 10.1 4.1 0.37 9.8 0.3 2.0 2 0 0 2 2 2 0 L-asparaginase II Mitofilin PF09731.9 KFH47836.1 - 0.5 9.1 4.9 0.81 8.5 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PEGSRP PF07623.11 KFH47836.1 - 0.54 10.1 13.4 2.1 8.3 3.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) DEAD PF00270.29 KFH47838.1 - 5.1e-43 146.9 0.1 7.1e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH47838.1 - 5.2e-22 78.3 0.0 1.6e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH47838.1 - 0.0004 20.4 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFH47838.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KFH47838.1 - 0.0042 17.4 0.1 0.014 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH47838.1 - 1.6 8.4 5.1 62 3.2 5.1 2.7 1 1 0 1 1 1 0 AAA domain Profilin PF00235.19 KFH47839.1 - 6.3e-40 136.4 0.0 7.2e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Profilin ADH_zinc_N PF00107.26 KFH47840.1 - 7e-31 106.9 0.3 1.2e-30 106.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH47840.1 - 5.2e-10 40.5 0.0 8.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH47840.1 - 6.8e-05 22.7 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KFH47840.1 - 0.00061 20.0 0.2 0.0011 19.3 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KFH47840.1 - 0.026 14.0 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KFH47840.1 - 0.48 9.7 7.7 0.63 9.3 6.0 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Terpene_synth_C PF03936.16 KFH47841.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Thioredoxin PF00085.20 KFH47842.1 - 8.1e-42 141.4 0.2 5.5e-27 93.8 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KFH47842.1 - 9.3e-11 42.0 0.0 3.9e-05 23.7 0.0 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFH47842.1 - 2.2e-06 28.1 1.5 0.014 15.9 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFH47842.1 - 5.8e-06 26.6 0.1 0.011 16.0 0.0 3.8 4 0 0 4 4 4 1 Thioredoxin-like TraF PF13728.6 KFH47842.1 - 0.00071 19.5 0.2 0.0039 17.0 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFH47842.1 - 0.0058 16.4 0.3 2.4 7.9 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin HyaE PF07449.11 KFH47842.1 - 0.0078 16.2 0.0 1.7 8.6 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 KFH47842.1 - 0.019 14.3 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFH47842.1 - 0.024 14.8 0.1 0.27 11.4 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 KFH47842.1 - 0.024 14.5 0.6 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family Cupin_1 PF00190.22 KFH47843.1 - 1.6e-15 57.0 0.5 2.1e-15 56.6 0.5 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFH47843.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Cupin domain DUF2415 PF10313.9 KFH47844.1 - 2.3e-11 43.4 0.0 4.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KFH47844.1 - 0.0003 21.0 0.0 3.5 8.0 0.0 3.7 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFH47844.1 - 0.2 12.2 0.8 1.1e+02 3.5 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 KFH47844.1 - 0.21 12.5 0.5 16 6.6 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Ras PF00071.22 KFH47845.1 - 8.5e-40 136.0 0.0 1.7e-37 128.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFH47845.1 - 4.3e-31 107.6 0.0 6.1e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH47845.1 - 7.3e-11 41.8 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFH47845.1 - 0.00046 20.3 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFH47845.1 - 0.0045 17.4 0.0 0.0075 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFH47845.1 - 0.017 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KFH47845.1 - 0.037 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFH47845.1 - 0.073 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 KFH47845.1 - 0.18 10.6 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 KFH47845.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain INCENP_ARK-bind PF03941.15 KFH47846.1 - 1.8e-22 79.0 1.2 5.8e-22 77.4 1.2 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Synaptobrevin PF00957.21 KFH47847.1 - 3.2e-14 52.5 0.7 4.8e-14 51.9 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFH47847.1 - 8.2e-13 48.2 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP68 PF16969.5 KFH47848.1 - 3.3e-201 670.1 7.5 3.8e-201 669.9 7.5 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF4510 PF14971.6 KFH47848.1 - 0.018 15.4 3.4 0.039 14.3 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) SNF2_N PF00176.23 KFH47849.1 - 4.8e-66 222.9 0.0 7e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH47849.1 - 1.5e-12 47.8 0.0 4.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KFH47849.1 - 3.7e-07 30.0 1.4 6.7e-07 29.2 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KFH47849.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFH47849.1 - 0.0023 18.0 0.0 0.026 14.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KFH47849.1 - 0.0033 17.3 0.3 0.0095 15.8 0.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFH47849.1 - 0.0033 17.3 0.6 0.0078 16.1 0.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH47849.1 - 0.0042 17.1 0.2 0.0098 15.9 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH47849.1 - 0.0098 16.2 0.4 0.023 15.1 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain HIRAN PF08797.11 KFH47849.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain zf-C3HC4_2 PF13923.6 KFH47849.1 - 1.8 8.4 6.1 7.4 6.5 6.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MOSC PF03473.17 KFH47850.1 - 8.3e-17 61.4 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFH47850.1 - 7.1e-11 42.0 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Metallophos PF00149.28 KFH47851.1 - 3.7e-38 132.1 0.4 5.9e-38 131.4 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFH47851.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3419 PF11899.8 KFH47852.1 - 3.6e-163 543.3 0.0 4.5e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KFH47852.1 - 5.5e-12 45.8 0.0 9.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH47852.1 - 1.1e-08 35.7 0.0 2.8e-06 28.0 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH47852.1 - 2.8e-08 34.4 0.0 1.3e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH47852.1 - 4e-08 33.2 0.0 1.5e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH47852.1 - 1.9e-07 31.6 0.0 0.00016 22.3 0.0 4.1 5 0 0 5 5 5 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH47852.1 - 1e-06 28.3 0.0 0.0044 16.4 0.0 2.9 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFH47852.1 - 0.00023 21.0 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S13 PF00416.22 KFH47854.1 - 8.6e-55 184.6 2.8 1e-54 184.4 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KFH47854.1 - 0.024 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin-6_N PF09177.11 KFH47854.1 - 0.048 14.2 0.0 0.18 12.4 0.0 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2746 PF10874.8 KFH47854.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) PP28 PF10252.9 KFH47854.1 - 0.15 12.5 0.7 0.28 11.7 0.2 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 ATP-synt PF00231.19 KFH47855.1 - 2.8e-79 266.7 1.4 3.4e-79 266.5 1.4 1.0 1 0 0 1 1 1 1 ATP synthase GNVR PF13807.6 KFH47855.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase zf-HC5HC2H_2 PF13832.6 KFH47856.1 - 1.2e-18 67.3 2.3 1.2e-18 67.3 2.3 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KFH47856.1 - 2.8e-17 62.7 0.0 5.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KFH47856.1 - 1.5e-11 44.3 3.7 1.5e-11 44.3 3.7 4.5 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.29 KFH47856.1 - 2.4e-11 43.4 51.2 1e-06 28.5 8.3 6.3 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 KFH47856.1 - 2.9e-07 29.9 5.9 2.9e-07 29.9 5.9 5.3 7 0 0 7 7 7 2 PHD-finger Prok-RING_1 PF14446.6 KFH47856.1 - 0.006 16.5 36.4 0.013 15.5 5.3 4.3 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 ELM2 PF01448.24 KFH47856.1 - 0.0071 17.1 0.2 0.024 15.4 0.2 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFH47856.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Metallophos PF00149.28 KFH47857.1 - 1.8e-10 41.7 0.2 2.7e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFH47857.1 - 3.2e-06 27.4 0.0 3.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hydrolase_4 PF12146.8 KFH47859.1 - 9.2e-12 44.7 0.1 3.1e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFH47859.1 - 2e-11 44.9 12.2 2e-11 44.9 12.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH47859.1 - 5.1e-06 26.3 5.5 1.1e-05 25.2 2.4 2.8 2 2 1 3 3 3 1 alpha/beta hydrolase fold Dus PF01207.17 KFH47860.1 - 7.1e-45 153.4 0.0 2.1e-44 151.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NUDIX_2 PF13869.6 KFH47861.1 - 7e-79 263.8 0.0 8.3e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RhoGAP PF00620.27 KFH47862.1 - 2.3e-27 95.7 0.0 3.5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SBDS_C PF09377.10 KFH47863.1 - 3e-43 146.5 0.0 4.9e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KFH47863.1 - 6.9e-36 122.2 0.1 1.2e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 KFH47863.1 - 0.081 12.9 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) tRNA-synt_His PF13393.6 KFH47865.1 - 4.8e-39 134.5 0.0 1.2e-32 113.5 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFH47865.1 - 2.2e-12 46.9 0.0 4.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFH47865.1 - 3.3e-05 23.5 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KFH47865.1 - 0.0032 17.5 0.0 0.009 16.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KFH47865.1 - 0.012 14.7 0.0 0.092 11.8 0.0 2.0 1 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) ELO PF01151.18 KFH47866.1 - 1.8e-80 270.1 5.6 2.1e-80 269.9 5.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Nop14 PF04147.12 KFH47867.1 - 1.1e-291 970.2 31.2 1.4e-291 969.9 31.2 1.1 1 0 0 1 1 1 1 Nop14-like family DUF702 PF05142.12 KFH47868.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) HAMP PF00672.25 KFH47869.1 - 9.6e-39 131.6 15.3 4.6e-08 33.3 0.4 7.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KFH47869.1 - 4.5e-31 107.7 1.1 1.4e-30 106.1 0.4 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFH47869.1 - 3e-26 91.8 0.7 4.7e-25 87.9 0.3 3.2 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 KFH47869.1 - 1.3e-16 60.4 5.9 1.7e-16 60.0 0.6 4.0 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KFH47869.1 - 8e-06 26.2 11.4 6.2 7.3 0.0 7.2 2 2 4 7 7 7 1 Syntaxin-like protein Fib_alpha PF08702.10 KFH47869.1 - 0.013 15.7 29.7 0.61 10.3 0.2 6.2 6 0 0 6 6 6 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KFH47869.1 - 0.015 15.5 46.0 1.7 8.9 2.8 9.6 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 KFH47869.1 - 0.023 14.3 23.5 1.2 8.7 6.1 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) GLE1 PF07817.13 KFH47869.1 - 0.024 13.8 3.1 15 4.7 0.0 4.4 2 1 2 4 4 4 0 GLE1-like protein DUF4279 PF14106.6 KFH47869.1 - 0.045 14.0 0.0 34 4.7 0.0 4.5 6 0 0 6 6 5 0 Domain of unknown function (DUF4279) DUF3829 PF12889.7 KFH47869.1 - 0.2 11.1 10.8 3.6 7.0 0.1 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF3829) GatB_Yqey PF02637.18 KFH47869.1 - 0.23 11.3 0.1 0.23 11.3 0.1 3.7 5 0 0 5 5 5 0 GatB domain GhoS PF11080.8 KFH47869.1 - 0.42 10.6 8.5 0.59 10.2 0.1 3.8 4 0 0 4 4 4 0 Endoribonuclease GhoS BORCS6 PF10157.9 KFH47869.1 - 0.9 9.8 12.0 7.5 6.8 0.2 5.6 3 2 2 6 6 6 0 BLOC-1-related complex sub-unit 6 PMC2NT PF08066.12 KFH47869.1 - 2.6 8.8 9.6 4.2 8.1 1.7 4.8 4 1 1 5 5 5 0 PMC2NT (NUC016) domain TetR_C_25 PF17933.1 KFH47869.1 - 2.7 8.4 5.9 18 5.7 0.0 4.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain MoaC PF01967.21 KFH47870.1 - 1e-54 184.3 4.0 1.7e-54 183.6 4.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KFH47870.1 - 2.4e-36 124.5 0.0 1.7e-35 121.8 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFH47870.1 - 1.5e-25 90.5 0.0 3.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFH47870.1 - 3.1e-05 24.3 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFH47870.1 - 0.055 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4187 PF13821.6 KFH47871.1 - 2.2e-21 75.3 1.9 6e-21 74.0 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFH47871.1 - 2.6e-10 40.0 3.7 5.9e-10 38.9 3.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFH47871.1 - 0.018 15.2 1.3 0.059 13.5 1.3 1.9 1 0 0 1 1 1 0 G-patch domain BTV_NS2 PF04514.12 KFH47871.1 - 0.041 12.7 6.6 0.06 12.2 6.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rimk_N PF18030.1 KFH47871.1 - 0.35 11.3 1.3 3.7 8.0 0.1 2.4 2 0 0 2 2 2 0 RimK PreATP-grasp domain Peptidase_M3 PF01432.20 KFH47872.1 - 4.4e-119 398.7 0.0 6.8e-119 398.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KFH47872.1 - 0.034 13.8 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Oxysterol_BP PF01237.18 KFH47873.1 - 9.8e-92 307.6 0.1 2e-89 300.1 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein RRM_1 PF00076.22 KFH47874.1 - 2e-10 40.4 0.0 5.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MARVEL PF01284.23 KFH47875.1 - 0.0061 16.6 5.5 0.0061 16.6 5.5 2.0 2 1 1 3 3 3 1 Membrane-associating domain MutS_V PF00488.21 KFH47876.1 - 1.5e-70 237.1 0.0 3.7e-70 235.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFH47876.1 - 2.1e-49 168.3 4.8 4.2e-49 167.4 4.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFH47876.1 - 3e-18 66.1 0.0 1.2e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KFH47876.1 - 7e-09 36.1 0.0 2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KFH47876.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH47876.1 - 0.22 12.0 0.0 0.63 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KFH47877.1 - 4.5e-54 183.5 0.0 7.1e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFH47877.1 - 3.1e-24 84.6 10.9 7.5e-17 61.0 0.4 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFH47877.1 - 2.4e-19 69.7 0.0 6e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KFH47877.1 - 9.5e-16 58.0 0.0 4.8e-15 55.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KFH47877.1 - 5.3e-08 32.4 1.5 7.8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KFH47877.1 - 0.00011 22.6 12.0 0.00027 21.2 0.1 4.4 2 1 1 3 3 3 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KFH47877.1 - 0.00014 21.9 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 KFH47877.1 - 0.0053 17.4 0.2 0.037 14.7 0.2 2.6 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 KFH47877.1 - 0.0067 16.4 0.0 0.041 13.9 0.0 2.4 1 0 0 1 1 1 1 SLIDE DnaJ PF00226.31 KFH47878.1 - 1.1e-10 41.4 2.1 2.8e-10 40.2 0.5 2.4 2 1 0 2 2 2 1 DnaJ domain RRS1 PF04939.12 KFH47879.1 - 3.6e-55 186.3 2.4 4.3e-55 186.0 2.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TonB_N PF16031.5 KFH47879.1 - 0.0083 16.6 3.0 0.017 15.7 3.0 1.5 1 0 0 1 1 1 1 TonB polyproline region Peptidase_M22 PF00814.25 KFH47880.1 - 1.1e-47 163.1 0.0 6.4e-46 157.2 0.0 2.8 1 1 0 1 1 1 1 Glycoprotease family Inositol_P PF00459.25 KFH47882.1 - 5.6e-42 144.1 0.0 1.4e-41 142.8 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family GMC_oxred_N PF00732.19 KFH47883.1 - 4.4e-46 157.6 0.2 7.2e-46 156.9 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFH47883.1 - 1e-26 94.2 0.9 5e-26 92.0 0.3 2.4 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFH47883.1 - 2e-07 30.6 0.2 2.1e-06 27.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH47883.1 - 5.4e-07 29.0 0.1 9.9e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 KFH47883.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH47883.1 - 0.0022 18.2 0.6 0.0069 16.6 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH47883.1 - 0.0063 15.8 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFH47883.1 - 0.007 15.8 0.5 0.01 15.2 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH47883.1 - 0.0084 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFH47883.1 - 0.099 13.2 0.0 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH47883.1 - 0.23 10.7 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3818 PF12825.7 KFH47884.1 - 1.6e-131 438.4 6.4 2.1e-131 438.0 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KFH47884.1 - 3.5e-39 133.8 0.3 7.2e-39 132.7 0.3 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KFH47884.1 - 4.6e-14 52.4 0.1 9.5e-13 48.1 0.0 3.2 3 1 0 3 3 3 1 PX domain Myc_N PF01056.18 KFH47884.1 - 0.3 11.0 2.2 0.25 11.2 0.2 1.8 2 0 0 2 2 2 0 Myc amino-terminal region AAA PF00004.29 KFH47885.1 - 1.6e-56 190.4 0.0 2.1e-43 147.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KFH47885.1 - 4.5e-28 97.5 0.3 1.2e-27 96.1 0.3 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFH47885.1 - 3.1e-12 46.1 2.9 3.5e-07 29.9 0.0 2.9 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 KFH47885.1 - 7.3e-10 39.5 9.2 7.2e-05 23.2 0.0 4.9 4 2 1 6 6 4 2 AAA ATPase domain AAA_18 PF13238.6 KFH47885.1 - 1.3e-06 28.9 0.0 0.0063 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFH47885.1 - 1.8e-06 28.2 0.0 0.055 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KFH47885.1 - 3e-06 26.9 0.0 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KFH47885.1 - 3.3e-06 27.1 0.2 0.003 17.5 0.0 3.1 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 KFH47885.1 - 8e-06 25.9 0.1 0.019 15.0 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFH47885.1 - 1.2e-05 25.6 1.9 0.029 14.6 0.2 3.7 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KFH47885.1 - 1.3e-05 25.2 0.2 0.17 11.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFH47885.1 - 2.5e-05 24.1 0.0 0.014 15.2 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFH47885.1 - 0.00019 21.6 0.1 0.23 11.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFH47885.1 - 0.00029 20.9 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFH47885.1 - 0.00043 19.6 0.0 0.85 8.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KFH47885.1 - 0.0016 18.8 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KFH47885.1 - 0.002 17.6 0.1 0.77 9.1 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFH47885.1 - 0.0029 17.3 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFH47885.1 - 0.0038 17.0 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFH47885.1 - 0.0038 16.5 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 KFH47885.1 - 0.0044 17.4 0.2 2.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KFH47885.1 - 0.0049 17.0 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KFH47885.1 - 0.0073 16.8 0.0 2.7 8.5 0.0 2.8 3 0 0 3 3 2 1 ABC transporter SKI PF01202.22 KFH47885.1 - 0.0075 16.4 0.1 0.91 9.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase AAA_25 PF13481.6 KFH47885.1 - 0.0088 15.6 2.3 1.3 8.5 0.1 3.6 3 1 1 4 4 4 1 AAA domain PEX-2N PF09263.10 KFH47885.1 - 0.011 16.0 0.0 7 7.1 0.0 2.6 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal NB-ARC PF00931.22 KFH47885.1 - 0.013 14.7 0.2 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 KFH47885.1 - 0.016 14.6 0.0 4 6.7 0.0 2.4 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 KFH47885.1 - 0.017 15.1 0.0 0.65 9.9 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KFH47885.1 - 0.029 14.6 0.1 8.4 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFH47885.1 - 0.03 14.2 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KFH47885.1 - 0.034 13.3 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFH47885.1 - 0.052 13.3 0.1 10 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFH47885.1 - 0.11 11.6 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KFH47885.1 - 0.13 11.5 0.7 11 5.1 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain Cytidylate_kin2 PF13189.6 KFH47885.1 - 0.14 12.3 0.5 7.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Cytidylate kinase-like family NTPase_1 PF03266.15 KFH47885.1 - 0.18 11.7 0.2 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 NTPase Fungal_trans PF04082.18 KFH47886.1 - 1.4e-12 47.2 0.3 3.3e-12 46.0 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFH47886.1 - 2.1e-12 46.8 6.2 1.3e-05 25.4 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH47886.1 - 2.9e-07 30.7 13.6 0.00048 20.7 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.18 KFH47886.1 - 4.7e-06 26.6 10.1 1.2e-05 25.3 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KFH47886.1 - 1.6e-05 25.1 5.0 0.022 15.2 0.5 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KFH47886.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFH47886.1 - 2.6 8.4 8.0 0.5 10.7 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Peptidase_M16_M PF16187.5 KFH47887.1 - 6.7e-97 324.1 0.5 9.6e-97 323.6 0.5 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KFH47887.1 - 3.9e-35 121.5 0.0 5.9e-21 75.3 0.0 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFH47887.1 - 4.1e-32 111.2 0.0 1.3e-31 109.6 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.32 KFH47888.1 - 0.011 16.6 0.4 12 6.9 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat CTP_transf_like PF01467.26 KFH47889.1 - 3e-19 69.6 0.0 4.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like zf-GRF PF06839.12 KFH47891.1 - 8.8e-06 25.7 7.1 1.8e-05 24.7 7.1 1.6 1 0 0 1 1 1 1 GRF zinc finger bZIP_1 PF00170.21 KFH47891.1 - 0.0045 17.0 0.1 0.0078 16.3 0.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor IHABP4_N PF16174.5 KFH47891.1 - 0.21 12.2 0.2 0.21 12.2 0.2 2.6 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal Cut12 PF11500.8 KFH47891.1 - 0.24 11.4 0.1 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Spindle pole body formation-associated protein AMP-binding PF00501.28 KFH47892.1 - 0 1522.4 0.0 1.1e-77 261.4 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KFH47892.1 - 0 1283.6 0.0 4.6e-51 173.9 0.0 9.8 9 1 0 9 9 9 9 Condensation domain PP-binding PF00550.25 KFH47892.1 - 4.4e-74 244.8 0.1 1.9e-13 50.6 0.1 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site p450 PF00067.22 KFH47892.1 - 5e-47 160.7 0.0 1.1e-46 159.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding_C PF13193.6 KFH47892.1 - 2.3e-12 47.7 0.0 0.00038 21.4 0.0 6.4 6 0 0 6 6 6 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KFH47892.1 - 0.011 14.5 0.0 1.8 7.1 0.0 3.3 4 0 0 4 4 4 0 Transferase family DUF5122 PF17164.4 KFH47892.1 - 0.32 11.3 5.4 48 4.4 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DAP3 PF10236.9 KFH47893.1 - 3e-86 289.4 0.0 3.9e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 zf-CHCC PF10276.9 KFH47894.1 - 6.1e-15 55.0 0.8 9.4e-15 54.4 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain ProQ PF04352.13 KFH47894.1 - 0.042 13.7 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 ProQ/FINO family PDEase_I PF00233.19 KFH47895.1 - 5e-64 216.3 0.0 7.4e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 KFH47896.1 - 1.1e-19 70.4 1.1 1.1e-19 70.4 1.1 3.2 4 0 0 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.6 KFH47896.1 - 4.9e-07 30.0 5.3 4.9e-07 30.0 5.3 3.8 4 0 0 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 KFH47896.1 - 0.00029 20.5 4.5 0.00029 20.5 4.5 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFH47896.1 - 0.00077 19.3 5.0 0.00077 19.3 5.0 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KFH47896.1 - 0.0025 18.1 2.6 0.0025 18.1 2.6 2.8 3 0 0 3 3 2 1 RING-like domain zf-RING_UBOX PF13445.6 KFH47896.1 - 0.01 15.8 6.2 0.01 15.8 6.2 3.8 3 0 0 3 3 3 0 RING-type zinc-finger DZR PF12773.7 KFH47896.1 - 0.045 13.8 6.0 2.2 8.4 3.8 2.9 2 0 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KFH47896.1 - 0.056 13.6 8.4 0.081 13.1 1.3 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 KFH47896.1 - 0.085 12.7 2.8 0.13 12.2 0.5 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-piccolo PF05715.13 KFH47896.1 - 0.49 10.6 11.2 0.88 9.8 4.1 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger DUF4690 PF15756.5 KFH47896.1 - 0.8 10.3 4.3 2.6 8.7 1.9 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage zinc_ribbon_2 PF13240.6 KFH47896.1 - 6.4 6.6 7.0 29 4.6 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain ABC_tran PF00005.27 KFH47898.1 - 8.1e-35 120.3 0.0 3.2e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KFH47898.1 - 6e-12 45.2 5.3 6e-12 45.2 5.3 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFH47898.1 - 1.8e-11 43.9 1.4 0.00038 20.0 0.1 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFH47898.1 - 2.7e-11 43.9 4.8 0.18 11.6 1.3 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFH47898.1 - 3e-06 27.2 0.1 0.19 11.4 0.0 3.3 3 1 0 4 4 4 2 AAA ATPase domain Fer4 PF00037.27 KFH47898.1 - 1e-05 25.2 2.7 1e-05 25.2 2.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.6 KFH47898.1 - 1.6e-05 25.2 0.2 0.0037 17.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFH47898.1 - 4.4e-05 23.9 0.0 0.053 13.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFH47898.1 - 5.2e-05 23.2 0.2 0.03 14.2 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4_10 PF13237.6 KFH47898.1 - 6e-05 23.1 8.9 0.0047 17.0 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain AAA_16 PF13191.6 KFH47898.1 - 0.00016 22.1 0.0 0.3 11.5 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFH47898.1 - 0.00027 20.6 0.3 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH47898.1 - 0.0003 20.7 0.1 0.77 9.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KFH47898.1 - 0.00042 20.9 0.0 0.08 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFH47898.1 - 0.00065 20.3 0.1 2.3 8.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain Fer4_21 PF14697.6 KFH47898.1 - 0.00078 19.5 10.8 0.0016 18.5 10.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 KFH47898.1 - 0.00086 19.1 1.6 0.092 12.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KFH47898.1 - 0.002 18.5 0.1 0.93 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KFH47898.1 - 0.0027 17.9 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KFH47898.1 - 0.0028 16.4 0.0 0.0028 16.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KFH47898.1 - 0.0029 17.3 2.9 0.073 12.7 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KFH47898.1 - 0.0033 17.4 0.8 0.56 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KFH47898.1 - 0.0037 17.0 0.3 2.6 7.7 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase Fer4_6 PF12837.7 KFH47898.1 - 0.0039 17.2 2.7 0.0039 17.2 2.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 KFH47898.1 - 0.004 17.7 6.5 0.011 16.3 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain NB-ARC PF00931.22 KFH47898.1 - 0.013 14.7 0.1 1.1 8.4 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain TsaE PF02367.17 KFH47898.1 - 0.014 15.4 0.1 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFH47898.1 - 0.016 14.7 1.2 0.16 11.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFH47898.1 - 0.019 15.2 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KFH47898.1 - 0.035 14.3 10.6 0.077 13.2 10.6 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_5 PF07728.14 KFH47898.1 - 0.042 13.8 0.7 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFH47898.1 - 0.058 13.1 0.3 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFH47898.1 - 0.088 12.9 0.5 26 4.9 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KFH47898.1 - 0.099 12.9 0.0 15 5.9 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 KFH47898.1 - 0.11 13.5 0.4 0.11 13.5 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KFH47898.1 - 0.18 11.5 0.0 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Mg_chelatase PF01078.21 KFH47898.1 - 0.19 11.1 0.5 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KFH47898.1 - 0.29 11.0 2.3 5.4 6.9 0.1 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KFH47898.1 - 0.43 10.3 4.5 0.73 9.6 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 KFH47898.1 - 3.1 8.1 10.7 0.28 11.3 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_membrane PF00664.23 KFH47899.1 - 2.1e-85 286.7 30.2 3e-48 164.8 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH47899.1 - 5.9e-64 214.7 0.0 5.9e-31 107.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH47899.1 - 5.7e-12 45.5 5.7 4.6e-05 22.9 1.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFH47899.1 - 4.1e-08 33.2 0.0 0.0023 17.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFH47899.1 - 1.1e-07 32.2 0.7 0.024 14.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KFH47899.1 - 1.9e-07 31.1 1.0 0.0079 15.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KFH47899.1 - 4.8e-07 28.9 0.0 0.08 11.7 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KFH47899.1 - 5.3e-07 29.7 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFH47899.1 - 6.9e-07 28.9 0.4 0.0017 18.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH47899.1 - 5.1e-06 27.1 1.2 0.0028 18.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH47899.1 - 5.3e-06 26.9 3.3 0.037 14.4 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFH47899.1 - 7.6e-06 25.9 0.1 0.31 10.8 0.1 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFH47899.1 - 7.9e-05 22.7 0.0 0.43 10.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFH47899.1 - 8e-05 22.3 0.2 0.69 9.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KFH47899.1 - 0.0014 18.6 0.0 0.5 10.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_membrane_3 PF13748.6 KFH47899.1 - 0.0018 17.6 0.2 0.0042 16.4 0.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA PF00004.29 KFH47899.1 - 0.0019 18.6 3.5 9.4 6.7 0.1 4.5 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFH47899.1 - 0.0026 17.3 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region PRK PF00485.18 KFH47899.1 - 0.0028 17.4 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 KFH47899.1 - 0.0036 17.2 0.0 0.92 9.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 KFH47899.1 - 0.0046 16.6 0.5 1.8 8.2 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KFH47899.1 - 0.0078 16.8 0.0 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFH47899.1 - 0.0083 16.3 0.0 0.41 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFH47899.1 - 0.0089 16.3 0.1 3.4 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KFH47899.1 - 0.024 14.8 2.8 4.2 7.7 0.5 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KFH47899.1 - 0.036 13.8 0.2 5.6 6.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFH47899.1 - 0.038 13.2 0.0 3.7 6.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KFH47899.1 - 0.042 13.1 0.0 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KFH47899.1 - 0.046 13.6 0.3 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KFH47899.1 - 0.059 13.5 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 KFH47899.1 - 0.066 12.8 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KFH47899.1 - 0.17 12.1 0.1 33 4.7 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFH47899.1 - 0.17 12.0 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFH47899.1 - 0.17 12.3 0.0 19 5.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ADK PF00406.22 KFH47900.1 - 5.1e-44 150.0 0.0 6.8e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFH47900.1 - 8.5e-36 123.4 0.0 1.2e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH47900.1 - 1.3e-07 32.2 0.0 2.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFH47900.1 - 5.7e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFH47900.1 - 0.00059 19.6 0.2 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase PT PF04886.12 KFH47900.1 - 0.006 16.1 11.5 0.015 14.9 11.5 1.6 1 0 0 1 1 1 1 PT repeat Zeta_toxin PF06414.12 KFH47900.1 - 0.11 11.8 0.1 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Prenyltrans PF00432.21 KFH47901.1 - 5.3e-59 195.6 10.1 1.9e-11 43.5 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFH47901.1 - 0.00032 19.9 0.3 0.13 11.3 0.1 3.1 1 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFH47901.1 - 0.0021 17.2 0.0 0.033 13.3 0.0 2.6 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain AAA_11 PF13086.6 KFH47903.1 - 2.7e-61 207.6 0.2 5.6e-61 206.6 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFH47903.1 - 2.4e-53 180.7 0.0 5e-53 179.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH47903.1 - 7.4e-13 48.6 0.0 1e-11 44.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH47903.1 - 9e-09 35.8 0.0 3.4e-08 34.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KFH47903.1 - 1e-06 28.6 0.0 0.4 10.4 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFH47903.1 - 5.2e-06 25.9 0.3 4.9e-05 22.7 0.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFH47903.1 - 9.7e-06 25.7 0.0 3.5e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFH47903.1 - 2.1e-05 24.4 0.1 0.0019 18.0 0.0 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KFH47903.1 - 0.00012 21.7 0.1 0.00049 19.7 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KFH47903.1 - 0.00026 20.9 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KFH47903.1 - 0.0007 19.9 0.1 0.048 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFH47903.1 - 0.0013 18.3 0.2 0.029 13.9 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFH47903.1 - 0.0027 17.5 0.0 0.012 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFH47903.1 - 0.0033 17.8 0.1 0.0079 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KFH47903.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KFH47903.1 - 0.0057 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KFH47903.1 - 0.0099 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Flavi_DEAD PF07652.14 KFH47903.1 - 0.015 15.3 0.1 0.056 13.4 0.1 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_5 PF07728.14 KFH47903.1 - 0.018 15.1 0.0 0.07 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 4HB_MCP_1 PF12729.7 KFH47903.1 - 0.019 14.5 0.9 0.027 14.0 0.1 1.6 2 0 0 2 2 1 0 Four helix bundle sensory module for signal transduction PhoH PF02562.16 KFH47903.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 KFH47903.1 - 0.024 15.0 0.3 0.11 12.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KFH47903.1 - 0.029 14.2 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain NTPase_1 PF03266.15 KFH47903.1 - 0.051 13.5 0.7 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 NTPase Zot PF05707.12 KFH47903.1 - 0.061 13.0 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PIF1 PF05970.14 KFH47903.1 - 0.076 12.2 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.7 KFH47903.1 - 0.083 11.8 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain ATPase PF06745.13 KFH47903.1 - 0.088 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KFH47903.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFH47903.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter UvrD_C PF13361.6 KFH47903.1 - 0.12 11.7 0.0 2.3 7.5 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain TTRAP PF14203.6 KFH47903.1 - 0.14 12.1 0.1 0.44 10.6 0.1 1.8 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Ribosomal_L30_N PF08079.12 KFH47903.1 - 1.8 8.9 6.0 4.2 7.7 6.0 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain DEAD PF00270.29 KFH47904.1 - 8.6e-48 162.4 0.0 2e-47 161.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH47904.1 - 8.8e-29 100.1 0.0 8.5e-28 96.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH47904.1 - 0.00093 19.2 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 KFH47904.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase APH PF01636.23 KFH47905.1 - 2.1e-10 40.9 0.3 3.9e-10 40.1 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH47905.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase FHA PF00498.26 KFH47907.1 - 4.8e-17 62.1 0.1 1e-16 61.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFH47907.1 - 1.7e-09 37.8 0.0 3.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MutS_V PF00488.21 KFH47908.1 - 2.9e-73 245.9 0.3 7.7e-73 244.5 0.1 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KFH47908.1 - 2.2e-36 125.9 3.4 4.5e-36 124.9 3.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFH47908.1 - 8.5e-30 103.3 0.0 2.1e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFH47908.1 - 9.7e-11 42.1 0.4 4.8e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 MutS domain II MutS_IV PF05190.18 KFH47908.1 - 3.1e-05 24.2 0.1 0.0001 22.6 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 KFH47908.1 - 0.0011 18.9 0.1 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) AAA_27 PF13514.6 KFH47908.1 - 0.1 12.1 0.2 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFH47908.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH47908.1 - 0.19 12.2 1.2 0.81 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain ORC6 PF05460.13 KFH47908.1 - 1.1 8.4 5.1 1.8 7.7 5.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Glyco_hydro_16 PF00722.21 KFH47909.1 - 7.9e-07 28.7 0.5 2.2e-05 24.0 0.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 Cupin_8 PF13621.6 KFH47910.1 - 3.8e-19 69.4 0.1 1.4e-14 54.4 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain F-box-like PF12937.7 KFH47910.1 - 3.8e-10 39.5 0.1 8.8e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 KFH47910.1 - 1e-09 38.8 0.0 2.4e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.33 KFH47910.1 - 5.5e-07 29.3 0.1 1.2e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.12 KFH47910.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein F-box_4 PF15966.5 KFH47910.1 - 0.15 12.0 0.1 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 F-box Kdo PF06293.14 KFH47911.1 - 0.00032 20.1 0.0 0.00071 19.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH47911.1 - 0.0012 18.8 0.6 0.0034 17.3 0.5 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFH47911.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Trs65 PF12735.7 KFH47912.1 - 3.2e-112 375.0 0.0 4.3e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SNARE_assoc PF09335.11 KFH47913.1 - 1.6e-15 57.6 5.0 1.6e-15 57.6 5.0 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1348 PF07080.11 KFH47914.1 - 7e-60 200.6 9.4 8e-60 200.5 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KFH47914.1 - 1.8e-08 35.0 0.4 2.3e-08 34.6 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFH47914.1 - 0.00038 20.8 0.0 0.00058 20.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 KFH47914.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase OTT_1508_deam PF14441.6 KFH47915.1 - 3.8e-17 62.0 0.1 6.9e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Adeno_E1B_19K PF01691.16 KFH47915.1 - 0.15 11.6 0.5 1.1 8.8 0.3 2.3 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen 14-3-3 PF00244.20 KFH47916.1 - 2.6e-106 354.1 3.9 3e-106 353.9 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm71 PF15602.6 KFH47916.1 - 0.085 12.9 0.2 2.3 8.3 0.0 2.2 1 1 0 2 2 2 0 Immunity protein 71 Ribosomal_L1 PF00687.21 KFH47917.1 - 1.1e-45 155.9 0.3 1.3e-45 155.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family BRF1 PF07741.13 KFH47918.1 - 0.064 13.6 4.2 2.6 8.5 0.2 2.5 2 1 0 2 2 2 0 Brf1-like TBP-binding domain DUF3275 PF11679.8 KFH47918.1 - 0.52 10.3 6.2 1.2 9.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) CorA PF01544.18 KFH47919.1 - 2.7e-10 40.0 1.8 6.6e-10 38.8 0.4 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Ureide_permease PF07168.11 KFH47919.1 - 0.11 11.2 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Ureide permease Zot PF05707.12 KFH47919.1 - 0.14 11.8 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) MFS_1 PF07690.16 KFH47920.1 - 4.4e-25 88.4 22.2 6.9e-25 87.7 21.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaA_N PF11638.8 KFH47920.1 - 0.0074 16.0 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 DnaA N-terminal domain eIF2_C PF09173.11 KFH47921.1 - 2.8e-34 117.2 0.5 6.9e-34 116.0 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFH47921.1 - 2e-22 79.7 1.5 2.2e-21 76.3 1.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFH47921.1 - 3.2e-10 40.2 0.4 1.5e-09 38.1 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH47921.1 - 0.0037 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFH47921.1 - 0.0053 16.8 1.1 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KFH47921.1 - 0.045 13.7 0.3 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase ApoO PF09769.9 KFH47922.1 - 4.9e-44 149.4 0.5 1.6e-43 147.8 0.0 2.0 3 0 0 3 3 3 1 Apolipoprotein O Arf PF00025.21 KFH47923.1 - 2.2e-74 248.6 0.0 2.5e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFH47923.1 - 1.4e-14 54.4 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFH47923.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFH47923.1 - 1.1e-11 44.5 0.3 1.7e-07 30.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFH47923.1 - 1.6e-11 44.1 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFH47923.1 - 2.1e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFH47923.1 - 8.1e-07 29.1 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFH47923.1 - 9.4e-05 22.0 0.0 0.0077 15.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFH47923.1 - 0.009 15.5 0.6 0.034 13.7 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KFH47923.1 - 0.13 12.8 0.1 0.22 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain Transcrip_reg PF01709.20 KFH47924.1 - 2e-61 207.5 0.0 2.3e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Cnd2 PF05786.14 KFH47925.1 - 0 1028.3 7.5 0 1028.0 7.5 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF3602 PF12223.8 KFH47925.1 - 0.041 14.5 0.1 0.21 12.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) CNDH2_N PF06278.11 KFH47925.1 - 0.046 13.9 1.9 0.064 13.5 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Alginate_lyase2 PF08787.11 KFH47926.1 - 2.7e-39 135.4 0.0 4e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Alginate lyase ELMO_CED12 PF04727.13 KFH47927.1 - 2.7e-48 164.4 0.0 5.3e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFH47927.1 - 3.2e-37 128.1 0.0 5.8e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KFH47927.1 - 1.2e-16 61.0 0.0 5.2e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) SR-25 PF10500.9 KFH47928.1 - 0.046 13.3 8.7 0.061 12.9 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 KFH47928.1 - 0.19 10.4 2.2 0.22 10.2 2.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Topoisom_I PF01028.20 KFH47929.1 - 7.7e-98 326.4 4.6 2e-97 325.0 4.6 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFH47929.1 - 1e-89 299.7 6.3 1e-89 299.7 6.3 3.1 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFH47929.1 - 5.3e-28 96.8 0.2 2.3e-27 94.7 0.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.25 KFH47930.1 - 1.1e-34 120.0 0.0 8.5e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH47930.1 - 4.9e-14 52.2 0.0 2.8e-12 46.5 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFH47930.1 - 0.0033 17.4 0.0 0.0073 16.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFH47930.1 - 0.094 12.0 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DnaJ_C PF01556.18 KFH47931.1 - 4.9e-36 124.0 0.1 6.8e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFH47931.1 - 3e-25 88.1 3.8 5.7e-25 87.2 3.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFH47931.1 - 3.1e-16 59.5 17.9 5.4e-16 58.7 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain PhnA_Zn_Ribbon PF08274.12 KFH47931.1 - 0.18 11.8 1.3 64 3.6 0.0 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Anti-TRAP PF15777.5 KFH47931.1 - 0.21 11.6 16.4 0.22 11.5 2.6 2.8 1 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_9 PF14369.6 KFH47931.1 - 0.54 10.6 2.8 32 4.9 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 KFH47931.1 - 0.6 10.1 9.1 0.48 10.5 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 KFH47931.1 - 1.5 9.0 6.7 2.1 8.4 1.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 KFH47931.1 - 2.7 8.1 8.0 71 3.5 8.0 2.3 1 1 0 1 1 1 0 zinc-ribbons MARVEL PF01284.23 KFH47932.1 - 0.053 13.6 11.1 0.065 13.3 9.2 2.0 1 1 1 2 2 2 0 Membrane-associating domain SfLAP PF11139.8 KFH47932.1 - 0.12 11.8 2.2 0.64 9.4 2.6 1.8 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein DUF3328 PF11807.8 KFH47932.1 - 0.15 11.8 0.6 16 5.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) DUF2700 PF10912.8 KFH47932.1 - 0.37 10.8 4.7 16 5.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2700) DUF2569 PF10754.9 KFH47932.1 - 2 8.8 8.4 0.33 11.4 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Vpu PF00558.19 KFH47932.1 - 3.4 7.5 6.3 3 7.7 0.7 2.7 2 1 1 3 3 3 0 Vpu protein 7tm_3 PF00003.22 KFH47932.1 - 9.3 5.9 12.4 1.4e+02 2.1 12.8 2.0 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF3074 PF11274.8 KFH47933.1 - 6.4e-59 199.0 1.1 2.3e-57 194.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Caldesmon PF02029.15 KFH47933.1 - 7.3e-06 25.0 18.6 1.3e-05 24.1 18.6 1.5 1 0 0 1 1 1 1 Caldesmon START PF01852.19 KFH47933.1 - 0.0089 15.5 0.0 0.024 14.0 0.1 1.7 2 0 0 2 2 2 1 START domain DUF2031 PF09592.10 KFH47933.1 - 6.2 6.3 14.6 9.9 5.6 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) tRNA-synt_1b PF00579.25 KFH47934.1 - 2.6e-18 66.4 0.0 5.3e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PMM PF03332.13 KFH47935.1 - 5.2e-103 343.6 0.0 6.1e-103 343.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KFH47935.1 - 0.028 14.1 0.0 0.27 10.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CAP_GLY PF01302.25 KFH47936.1 - 3.3e-17 62.2 0.7 1.4e-16 60.3 0.5 2.1 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KFH47936.1 - 4.4e-07 29.6 9.5 0.00019 21.2 1.6 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF4407 PF14362.6 KFH47936.1 - 0.00061 19.2 6.3 0.00061 19.2 6.3 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KFH47936.1 - 0.0012 17.6 2.4 0.0012 17.6 2.4 2.8 2 1 0 3 3 3 1 AAA domain Spc7 PF08317.11 KFH47936.1 - 0.0029 16.5 27.7 0.4 9.5 3.3 3.5 2 1 2 4 4 4 4 Spc7 kinetochore protein ADIP PF11559.8 KFH47936.1 - 0.0049 17.0 14.9 0.14 12.3 0.5 3.8 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 KFH47936.1 - 0.0086 15.5 8.2 3.1 7.1 0.3 3.2 3 0 0 3 3 3 2 FAM76 protein Med4 PF10018.9 KFH47936.1 - 0.014 15.1 2.6 0.014 15.1 2.6 2.8 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.20 KFH47936.1 - 0.048 13.6 19.4 0.35 10.8 2.5 3.8 2 1 1 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 KFH47936.1 - 0.062 13.8 7.1 4.7 7.8 0.4 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KFH47936.1 - 0.077 13.2 0.3 0.077 13.2 0.3 4.6 4 1 0 4 4 3 0 Autophagy protein 16 (ATG16) DUF1857 PF08982.11 KFH47936.1 - 0.078 12.8 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Sec2p PF06428.11 KFH47936.1 - 0.27 11.2 17.6 0.35 10.9 0.9 4.4 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p DUF745 PF05335.13 KFH47936.1 - 0.28 10.9 14.5 0.67 9.6 1.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF745) EzrA PF06160.12 KFH47936.1 - 0.32 9.1 12.9 0.1 10.8 8.2 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Spc29 PF17082.5 KFH47936.1 - 0.34 10.7 14.3 0.089 12.6 6.3 2.5 2 1 0 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 KFH47936.1 - 0.35 10.9 11.4 1.3 9.0 1.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KFH47936.1 - 0.71 8.7 20.5 0.94 8.3 13.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KFH47936.1 - 1.4 9.0 6.5 3.1 7.8 0.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEARLI-4 PF05278.12 KFH47936.1 - 1.8 8.1 13.0 3 7.3 6.1 2.5 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) RasGAP_C PF03836.15 KFH47936.1 - 2.3 8.4 5.2 34 4.6 0.1 3.2 3 0 0 3 3 3 0 RasGAP C-terminus BLOC1_2 PF10046.9 KFH47936.1 - 2.3 8.6 18.6 0.63 10.4 2.9 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF241 PF03087.14 KFH47936.1 - 2.3 8.0 10.1 0.26 11.1 1.3 3.0 4 0 0 4 4 4 0 Arabidopsis protein of unknown function TMF_DNA_bd PF12329.8 KFH47936.1 - 2.6 8.1 36.3 0.061 13.3 4.5 5.2 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding GspL_C PF12693.7 KFH47936.1 - 2.6 7.9 5.0 25 4.7 0.6 2.5 1 1 1 2 2 2 0 GspL periplasmic domain XLF PF09302.11 KFH47936.1 - 2.7 8.1 12.2 23 5.1 0.3 4.0 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SHE3 PF17078.5 KFH47936.1 - 3.4 7.3 16.1 11 5.6 11.0 2.7 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 KFH47936.1 - 3.6 7.4 18.0 1.2 8.9 4.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DHR10 PF18595.1 KFH47936.1 - 4.9 7.2 35.2 0.56 10.3 9.8 4.0 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KFH47936.1 - 5.4 7.4 28.0 18 5.7 10.2 3.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 KFH47936.1 - 9 7.0 28.2 3.1 8.5 1.3 4.9 3 1 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.12 KFH47936.1 - 9.4 6.3 11.3 5.7 7.0 1.4 3.5 3 0 0 3 3 3 0 Laminin Domain II DUF16 PF01519.16 KFH47936.1 - 9.8 6.7 8.9 52 4.4 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 DEAD PF00270.29 KFH47937.1 - 6.9e-17 61.8 0.0 1.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH47937.1 - 8e-06 26.2 0.0 5e-05 23.6 0.0 2.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH47937.1 - 0.00036 20.6 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KFH47937.1 - 0.0069 17.0 0.0 0.062 13.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.6 KFH47937.1 - 0.16 12.2 1.7 1 9.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain Glyco_hydro_16 PF00722.21 KFH47938.1 - 1.4e-39 135.4 0.5 2.1e-39 134.8 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MSA-2c PF12238.8 KFH47939.1 - 1.2 9.1 4.1 2.1 8.3 4.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c IATP PF04568.12 KFH47940.1 - 1.1e-32 112.3 2.1 1.3e-32 112.1 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HAMP PF00672.25 KFH47940.1 - 0.052 13.9 0.2 0.79 10.1 0.1 2.3 2 0 0 2 2 2 0 HAMP domain DUF2205 PF10224.9 KFH47940.1 - 0.11 12.6 4.6 0.15 12.1 4.6 1.3 1 0 0 1 1 1 0 Short coiled-coil protein Nop25 PF09805.9 KFH47940.1 - 0.46 10.9 9.6 0.58 10.6 9.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FYVE PF01363.21 KFH47941.1 - 3.4e-16 59.1 8.0 7.4e-16 58.1 8.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KFH47941.1 - 0.035 14.3 8.3 0.035 14.3 8.3 2.5 3 0 0 3 3 3 0 AN1-like Zinc finger Pex14_N PF04695.13 KFH47941.1 - 0.84 10.3 12.0 0.14 12.8 2.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-DNA_Pol PF08996.10 KFH47941.1 - 1.9 8.2 7.7 11 5.7 3.5 2.7 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Arm_3 PF16186.5 KFH47942.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Atypical Arm repeat UQ_con PF00179.26 KFH47943.1 - 2.8e-23 82.1 0.0 3.2e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH47943.1 - 5.2e-06 26.2 0.0 8.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFH47943.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KFH47943.1 - 0.015 15.5 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain PCI PF01399.27 KFH47944.1 - 1.2e-14 54.7 0.3 1.4e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KFH47944.1 - 1.1e-09 37.8 0.8 1.1e-09 37.8 0.8 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Vps35 PF03635.17 KFH47944.1 - 0.017 13.6 0.0 0.24 9.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 WD40 PF00400.32 KFH47945.1 - 0.044 14.7 1.8 21 6.2 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 KFH47945.1 - 0.1 12.6 0.2 8.3 6.5 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Dot_icm_IcmQ PF09475.10 KFH47946.1 - 0.061 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF2428 PF10350.9 KFH47948.1 - 2.4e-60 204.1 0.0 5.4e-60 203.0 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KFH47948.1 - 5.6e-08 32.4 9.9 0.41 11.0 0.0 7.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFH47948.1 - 1.9e-07 31.3 2.3 1.4 9.3 0.1 6.4 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 KFH47948.1 - 0.017 15.6 0.6 2.1 8.9 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat MMS22L_C PF14911.6 KFH47948.1 - 0.056 12.5 0.2 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal HEAT_2 PF13646.6 KFH47949.1 - 1.9e-11 44.2 1.8 0.095 13.1 0.0 6.6 5 2 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KFH47949.1 - 3.7e-06 27.4 0.0 0.031 14.9 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFH47949.1 - 1.4e-05 25.2 0.0 0.82 9.7 0.0 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFH47949.1 - 0.00016 21.6 13.8 0.4 11.1 0.0 8.8 11 0 0 11 11 11 2 HEAT repeat UNC45-central PF11701.8 KFH47949.1 - 0.063 13.2 0.0 3 7.8 0.0 3.7 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KFH47949.1 - 0.35 11.4 0.0 0.35 11.4 0.0 7.5 8 2 1 9 9 9 0 HEAT-like repeat Halogen_Hydrol PF10112.9 KFH47950.1 - 0.039 14.0 0.2 0.047 13.7 0.2 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein KxDL PF10241.9 KFH47950.1 - 0.047 14.0 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein Nsp1_C PF05064.13 KFH47950.1 - 0.07 12.9 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region CLZ PF16526.5 KFH47950.1 - 0.07 13.5 0.4 0.095 13.1 0.4 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APH PF01636.23 KFH47951.1 - 6.7e-12 45.8 0.7 1.2e-11 45.0 0.7 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KFH47951.1 - 0.0012 18.9 4.5 0.0023 18.1 4.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Clavanin PF05452.11 KFH47951.1 - 0.24 11.6 1.6 0.54 10.5 0.3 2.2 3 0 0 3 3 3 0 Clavanin Nsp1_C PF05064.13 KFH47953.1 - 1.1e-38 131.6 3.0 1.1e-38 131.6 3.0 2.1 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KFH47953.1 - 2.4e-15 57.2 199.4 1.7e-06 28.8 29.0 7.6 2 1 7 9 9 8 7 Nucleoporin FG repeat region V-SNARE PF05008.15 KFH47953.1 - 0.42 11.0 7.0 0.91 9.9 0.6 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ERM PF00769.19 KFH47953.1 - 0.42 10.4 8.3 0.68 9.7 8.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NPV_P10 PF05531.12 KFH47953.1 - 0.53 10.8 1.3 1.9 9.0 0.1 2.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein MAS20 PF02064.15 KFH47953.1 - 0.61 10.2 2.1 1.3 9.2 2.1 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Laminin_II PF06009.12 KFH47953.1 - 0.64 10.0 7.1 2.3 8.2 0.5 2.5 2 1 0 2 2 2 0 Laminin Domain II Mer2 PF09074.10 KFH47953.1 - 0.77 9.5 5.2 0.47 10.2 0.8 2.1 2 0 0 2 2 2 0 Mer2 DUF1664 PF07889.12 KFH47953.1 - 1.3 9.1 4.4 22 5.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MIP-T3_C PF17749.1 KFH47953.1 - 1.4 8.9 7.1 0.74 9.8 0.1 3.0 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region FPP PF05911.11 KFH47953.1 - 1.4 7.1 8.6 4.9 5.2 5.8 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil KxDL PF10241.9 KFH47953.1 - 2 8.8 4.2 22 5.4 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF4201 PF13870.6 KFH47953.1 - 2.1 8.1 5.2 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 KFH47953.1 - 2.5 8.5 10.9 0.38 11.1 2.1 2.9 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_13 PF13166.6 KFH47953.1 - 3.1 6.3 7.0 3.7 6.1 1.8 2.0 1 1 1 2 2 2 0 AAA domain DUF4200 PF13863.6 KFH47953.1 - 3.5 8.1 9.0 25 5.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.6 KFH47953.1 - 5.3 6.3 7.7 4.5 6.6 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KFH47953.1 - 6.7 7.3 8.0 4.1 8.0 1.7 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 KFH47953.1 - 8.2 6.5 9.0 36 4.4 0.0 3.8 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Ribul_P_3_epim PF00834.19 KFH47954.1 - 1.9e-62 210.2 0.0 8.2e-62 208.1 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KFH47954.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 KFH47954.1 - 0.091 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Hydrolase_4 PF12146.8 KFH47956.1 - 8.3e-09 35.1 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH47956.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KFH47956.1 - 8.4e-05 21.5 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 KFH47956.1 - 0.00088 18.9 0.0 0.002 17.7 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFH47956.1 - 0.003 17.1 0.0 0.0082 15.6 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family SLD3 PF08639.10 KFH47957.1 - 2.8e-160 534.7 10.2 2.8e-160 534.7 10.2 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 ArfGap PF01412.18 KFH47959.1 - 3.9e-33 114.0 0.5 1.1e-32 112.5 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFH47959.1 - 6e-24 85.1 14.4 9.5e-24 84.4 14.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFH47959.1 - 9.3e-13 48.6 0.1 2.2e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 PH domain DUF202 PF02656.15 KFH47960.1 - 1e-20 74.0 3.8 1e-20 74.0 3.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.8 KFH47960.1 - 0.15 11.9 1.9 0.22 11.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Proteasome PF00227.26 KFH47961.1 - 2.5e-45 154.3 0.0 3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PRA1 PF03208.19 KFH47962.1 - 3.1e-32 111.2 1.0 4.4e-32 110.7 1.0 1.2 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 KFH47962.1 - 0.31 11.7 3.0 0.28 11.8 0.2 2.2 2 0 0 2 2 2 0 Renin receptor-like protein PV-1 PF06637.11 KFH47962.1 - 2.8 6.7 7.1 4.2 6.1 7.1 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-CCHC PF00098.23 KFH47963.1 - 6e-08 32.4 2.0 1e-07 31.7 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle MPP6 PF10175.9 KFH47963.1 - 9.9e-06 26.1 16.5 0.0029 18.1 16.2 3.0 1 1 1 2 2 2 1 M-phase phosphoprotein 6 zf-CCHC_4 PF14392.6 KFH47963.1 - 0.091 12.5 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle BNIP2 PF12496.8 KFH47963.1 - 5 7.6 12.2 96 3.4 12.2 2.1 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RR_TM4-6 PF06459.12 KFH47963.1 - 5.4 6.8 10.2 7.7 6.3 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C2H2 PF00096.26 KFH47964.1 - 4.6e-13 48.8 10.9 1.7e-06 28.2 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH47964.1 - 3.2e-08 33.7 9.2 0.002 18.8 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH47964.1 - 4.1e-08 33.3 12.3 1.8e-07 31.3 4.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KFH47964.1 - 4.3e-07 30.1 4.2 9.7e-05 22.6 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFH47964.1 - 2.3e-06 27.7 3.7 0.0013 19.0 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFH47964.1 - 0.00019 21.3 11.0 0.0056 16.6 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFH47964.1 - 0.012 15.2 3.4 1.5 8.5 0.1 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFH47964.1 - 0.025 14.6 1.5 0.025 14.6 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 KFH47964.1 - 0.065 12.8 2.0 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFH47964.1 - 0.12 13.1 0.8 5.5 7.7 0.1 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFH47964.1 - 0.27 11.0 5.7 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFH47964.1 - 0.74 10.2 4.1 12 6.3 0.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFH47964.1 - 1.6 8.9 5.6 8.8 6.5 0.8 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFH47964.1 - 6.3 6.8 8.0 5.7 7.0 2.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KFH47964.1 - 9.4 6.8 7.5 1.1e+02 3.3 7.5 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 KFH47964.1 - 9.4 6.4 6.6 21 5.2 1.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF2383 PF09537.10 KFH47965.1 - 0.14 12.5 0.2 2.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Na_Ca_ex PF01699.24 KFH47966.1 - 2.2e-50 170.5 41.2 1.1e-27 96.9 16.5 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MARVEL PF01284.23 KFH47966.1 - 0.0031 17.5 0.3 0.0031 17.5 0.3 3.7 2 1 1 3 3 3 1 Membrane-associating domain DUF4481 PF14800.6 KFH47966.1 - 0.26 10.7 0.7 4.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) zf-CCCH PF00642.24 KFH47967.1 - 0.00022 21.1 19.8 0.0018 18.1 1.0 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFH47967.1 - 0.0057 16.4 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFH47967.1 - 0.56 10.3 10.5 0.38 10.9 0.6 3.4 3 0 0 3 3 3 0 Zinc finger domain DUF5102 PF17104.5 KFH47968.1 - 1.2e-107 360.3 3.9 2e-107 359.6 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) MCM PF00493.23 KFH47969.1 - 8.7e-104 345.5 0.0 1.3e-103 344.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFH47969.1 - 1.7e-29 102.2 1.0 3.2e-29 101.3 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFH47969.1 - 1.1e-21 77.0 0.5 2.6e-21 75.8 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFH47969.1 - 1.6e-17 64.0 3.1 5.7e-17 62.2 3.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFH47969.1 - 1.4e-07 31.1 0.0 1.2e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFH47969.1 - 4e-06 26.9 0.0 2.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KFH47969.1 - 0.0024 17.7 0.0 0.0077 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KFH47969.1 - 0.019 14.8 0.0 0.07 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KFH47969.1 - 0.049 14.3 1.5 0.14 12.8 0.1 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal UPF0047 PF01894.17 KFH47970.1 - 1.3e-36 125.3 0.0 1.5e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RL10P_insert PF17777.1 KFH47971.1 - 7.6e-23 80.3 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFH47971.1 - 2.5e-22 78.9 0.0 6.2e-22 77.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KFH47971.1 - 8.3e-18 64.8 5.7 8.3e-18 64.8 5.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MFS_2 PF13347.6 KFH47972.1 - 8.2e-10 37.8 12.0 1.6e-09 36.9 1.2 2.7 2 0 0 2 2 2 2 MFS/sugar transport protein Rota_VP4_MID PF17477.2 KFH47972.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain RRM_1 PF00076.22 KFH47973.1 - 2.1e-17 62.7 0.0 4.4e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFH47973.1 - 5.7e-06 26.8 14.7 5.7e-06 26.8 14.7 3.0 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 HMG_box PF00505.19 KFH47974.1 - 6.2e-15 55.4 1.1 6.2e-15 55.4 1.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFH47974.1 - 2.9e-14 53.4 1.1 2.9e-14 53.4 1.1 2.0 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.30 KFH47974.1 - 2.9e-11 43.6 0.0 5.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFH47974.1 - 3.1e-09 36.8 0.3 1.3e-08 34.9 0.0 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) WYL_3 PF18488.1 KFH47974.1 - 0.038 14.3 2.5 0.085 13.2 2.5 1.5 1 0 0 1 1 1 0 WYL domain DUF5613 PF18467.1 KFH47974.1 - 0.16 12.4 3.6 0.28 11.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) SMC_ScpA PF02616.14 KFH47974.1 - 0.54 10.1 1.3 0.79 9.6 1.3 1.1 1 0 0 1 1 1 0 Segregation and condensation protein ScpA CDK2AP PF09806.9 KFH47974.1 - 6.9 6.7 8.0 0.32 11.0 2.2 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Diphthami_syn_2 PF01902.17 KFH47975.1 - 1.2e-19 70.7 0.0 8.5e-14 51.6 0.0 3.1 3 0 0 3 3 3 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KFH47975.1 - 5.2e-10 39.4 0.1 7.5e-06 26.0 0.0 3.6 3 1 0 3 3 3 3 Endoribonuclease L-PSP C2 PF00168.30 KFH47976.1 - 3.2e-84 277.9 0.0 1.4e-23 83.1 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KFH47976.1 - 0.00034 20.2 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Cgr1 PF03879.14 KFH47977.1 - 2.6e-33 114.6 27.9 3e-33 114.4 27.9 1.0 1 0 0 1 1 1 1 Cgr1 family STAT_bind PF02864.15 KFH47977.1 - 1.4 9.5 6.7 1.8 9.1 6.7 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain DUF4192 PF13830.6 KFH47977.1 - 1.9 8.5 6.7 2.3 8.2 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) UQ_con PF00179.26 KFH47978.1 - 1.7e-32 112.0 0.0 2.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH47978.1 - 0.0094 15.6 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B BphX PF06139.12 KFH47978.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 2 0 0 2 2 2 0 BphX-like Prok-E2_E PF14462.6 KFH47978.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E Glyco_transf_22 PF03901.17 KFH47979.1 - 3.2e-63 214.4 19.1 4.2e-63 214.0 19.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Wzy_C PF04932.15 KFH47979.1 - 0.3 10.7 3.2 1.2 8.8 1.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase FF PF01846.19 KFH47980.1 - 3.6e-46 155.1 15.0 4.7e-13 49.1 0.0 6.7 6 1 0 6 6 6 5 FF domain WW PF00397.26 KFH47980.1 - 1.9e-17 63.0 20.1 2e-09 37.4 5.8 2.7 2 0 0 2 2 2 2 WW domain Lipin_mid PF16876.5 KFH47980.1 - 0.062 13.4 0.1 2.5 8.3 0.1 2.8 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain HycH PF07450.11 KFH47980.1 - 0.071 13.5 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH RhoGAP-FF1 PF16512.5 KFH47980.1 - 0.22 12.2 13.6 8.3 7.2 0.2 4.9 5 2 0 5 5 5 0 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KFH47980.1 - 5.9 7.2 7.6 26 5.1 0.3 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Cytochrom_B562 PF07361.11 KFH47980.1 - 7.7 7.2 7.2 2.9 8.6 1.3 2.9 3 0 0 3 3 3 0 Cytochrome b562 tRNA-synt_1 PF00133.22 KFH47982.1 - 1.7e-223 743.3 1.0 2.2e-222 739.6 1.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFH47982.1 - 1.7e-33 115.8 1.2 4.5e-33 114.4 1.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFH47982.1 - 5.3e-13 48.5 0.5 1.6e-06 27.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFH47982.1 - 8.3e-13 48.3 0.7 2.4e-09 36.9 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KFH47982.1 - 2.1e-05 24.7 7.1 2.1e-05 24.7 7.1 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Erp_C PF06780.11 KFH47982.1 - 0.44 10.6 3.1 1.1 9.2 3.1 1.6 1 0 0 1 1 1 0 Erp protein C-terminus Amino_oxidase PF01593.24 KFH47983.1 - 1.4e-84 285.0 0.1 4.5e-70 237.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFH47983.1 - 3e-13 49.9 0.0 7.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain HMG_box_2 PF09011.10 KFH47983.1 - 2.6e-09 37.6 7.9 2.6e-09 37.6 7.9 2.3 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.19 KFH47983.1 - 5.1e-09 36.4 12.2 5.2e-08 33.2 6.7 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 KFH47983.1 - 9.5e-08 32.2 0.0 2.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH47983.1 - 0.0015 18.1 2.2 0.0019 17.8 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH47983.1 - 0.0065 15.7 0.1 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH47983.1 - 0.11 12.4 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Packaging_FI PF14000.6 KFH47983.1 - 0.33 11.4 3.3 0.65 10.4 3.3 1.4 1 0 0 1 1 1 0 DNA packaging protein FI HrpB7 PF09486.10 KFH47984.1 - 0.0032 17.9 6.2 0.068 13.6 1.4 2.5 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) DUF2721 PF11026.8 KFH47984.1 - 0.0047 16.8 1.2 0.011 15.6 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) Spc29 PF17082.5 KFH47984.1 - 0.047 13.5 4.6 0.94 9.3 0.6 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 KFH47984.1 - 0.057 13.5 0.3 2 8.5 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KFH47984.1 - 0.061 13.4 0.2 0.096 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 KFH47984.1 - 0.065 13.4 3.6 8.9 6.6 0.1 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 KFH47984.1 - 0.11 12.8 2.6 0.36 11.1 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KFH47984.1 - 0.11 12.7 0.7 0.57 10.4 0.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 KFH47984.1 - 0.19 12.2 2.7 14 6.2 0.0 2.8 2 1 1 3 3 3 0 Cell division protein ZapB BLOC1_2 PF10046.9 KFH47984.1 - 0.24 11.7 1.2 23 5.4 0.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCU PF04678.13 KFH47984.1 - 0.39 10.8 1.4 2.4 8.2 1.4 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter adh_short_C2 PF13561.6 KFH47985.1 - 2.4e-43 148.4 2.5 3e-43 148.1 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH47985.1 - 2.4e-38 131.6 0.1 3e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH47985.1 - 2.3e-10 40.7 1.2 3.7e-10 40.0 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFH47985.1 - 0.12 12.3 1.5 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFH47985.1 - 0.12 13.0 1.1 0.2 12.2 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_34 PF05637.12 KFH47986.1 - 1e-65 221.9 1.0 1.5e-65 221.3 1.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DEAD PF00270.29 KFH47987.1 - 1.5e-44 151.9 1.1 2.4e-44 151.2 1.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH47987.1 - 4.6e-32 110.7 0.2 8.8e-31 106.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH47987.1 - 2e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFH47987.1 - 0.00016 21.5 0.1 0.00033 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFH47987.1 - 0.0009 19.6 1.5 0.004 17.5 0.5 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KFH47987.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 KFH47987.1 - 0.02 15.1 0.8 0.1 12.8 0.8 2.1 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KFH47987.1 - 0.077 13.0 0.2 0.37 10.8 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.25 KFH47987.1 - 0.089 12.1 0.2 0.48 9.7 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) fragilysinNterm PF16376.5 KFH47987.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin UvrD-helicase PF00580.21 KFH47987.1 - 0.12 11.9 0.2 0.19 11.2 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mitoc_mL59 PF18126.1 KFH47988.1 - 3.6e-43 147.0 2.2 6.6e-43 146.1 2.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KFH47988.1 - 7.3e-18 64.0 0.4 1.2e-17 63.4 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KFH47988.1 - 7.8e-12 45.1 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Anp1 PF03452.14 KFH47989.1 - 2.4e-108 361.6 0.0 2.8e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFH47989.1 - 0.0018 18.1 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HAD_2 PF13419.6 KFH47990.1 - 3.3e-17 63.2 0.0 8.9e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFH47990.1 - 5.7e-09 36.6 0.0 4.4e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH47990.1 - 7.6e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KFH47990.1 - 0.0085 16.5 0.0 0.036 14.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 KFH47990.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 AIB PF15334.6 KFH47990.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein DUF2834 PF11196.8 KFH47991.1 - 0.00018 21.8 1.9 0.045 14.1 0.3 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2834) DUF1771 PF08590.10 KFH47992.1 - 8.5e-15 54.9 11.6 8.5e-15 54.9 11.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KFH47992.1 - 1.3e-08 34.6 8.4 3e-06 27.1 0.6 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KFH47992.1 - 3.2e-08 33.3 3.8 0.001 18.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 KFH47992.1 - 6.1e-07 29.7 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 KFH47992.1 - 1e-05 25.2 11.2 0.00014 21.6 0.3 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFH47992.1 - 6.2e-05 23.3 4.4 0.11 13.0 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 KFH47992.1 - 0.00031 21.0 0.2 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 KFH47992.1 - 0.047 13.9 2.4 2 8.7 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KFH47992.1 - 1.3 9.7 5.5 2.2 9.0 0.4 2.5 1 1 1 2 2 2 0 Torus domain Pet100 PF09803.9 KFH47993.1 - 7.9e-19 67.9 0.2 9.9e-19 67.6 0.2 1.1 1 0 0 1 1 1 1 Pet100 Skp1 PF01466.19 KFH47995.1 - 1.5e-29 101.9 0.4 3.4e-29 100.7 0.4 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFH47995.1 - 3e-20 72.2 1.6 4.8e-20 71.5 0.0 2.1 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain Sec1 PF00995.23 KFH47998.1 - 5.1e-126 422.2 0.0 5.7e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DGCR6 PF07324.11 KFH47998.1 - 0.068 12.8 1.1 0.26 10.9 0.5 2.2 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein FAD_binding_2 PF00890.24 KFH48000.1 - 5.7e-123 411.1 2.2 7e-123 410.8 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFH48000.1 - 6.3e-43 145.8 0.2 9.4e-43 145.3 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KFH48000.1 - 2.7e-05 23.5 0.2 0.017 14.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KFH48000.1 - 4.6e-05 22.8 0.6 0.025 13.8 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFH48000.1 - 0.00016 20.9 0.5 0.047 12.8 1.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFH48000.1 - 0.006 15.9 0.5 0.016 14.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFH48000.1 - 0.1 12.1 1.3 0.22 11.1 1.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFH48000.1 - 0.16 10.7 0.6 0.71 8.5 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_38N PF01074.22 KFH48001.1 - 3.4e-86 289.2 0.2 5.2e-86 288.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFH48001.1 - 9.5e-50 169.6 0.0 2e-49 168.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFH48001.1 - 1.5e-27 95.6 0.0 3.1e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFH48001.1 - 2.2e-11 43.7 0.0 5.5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_15 PF00723.21 KFH48001.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 CorA PF01544.18 KFH48002.1 - 9.7e-39 133.4 0.4 7.1e-38 130.6 0.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Osmo_CC PF08946.10 KFH48002.1 - 0.075 13.3 0.5 0.19 12.0 0.5 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil ORC6 PF05460.13 KFH48002.1 - 0.77 9.0 7.9 1.9 7.7 7.9 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Spt20 PF12090.8 KFH48002.1 - 7.2 6.2 10.1 14 5.2 10.1 1.4 1 0 0 1 1 1 0 Spt20 family R3H PF01424.22 KFH48003.1 - 1.6e-14 53.6 0.8 3e-14 52.8 0.8 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KFH48003.1 - 0.00025 21.0 34.8 0.00067 19.7 14.1 15.0 14 2 1 15 15 15 6 NF-X1 type zinc finger Hydrolase_4 PF12146.8 KFH48004.1 - 9.2e-10 38.2 0.0 1.5e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFH48004.1 - 1.5e-09 38.8 2.1 1.5e-09 38.8 2.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH48004.1 - 5e-09 36.2 0.0 7.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFH48004.1 - 3.3e-05 23.9 0.5 7.6e-05 22.7 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFH48004.1 - 0.0032 17.0 0.0 0.087 12.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFH48004.1 - 0.029 14.2 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFH48004.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase HRG PF16954.5 KFH48004.1 - 0.15 12.5 0.3 0.38 11.2 0.3 1.6 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Peptidase_M24 PF00557.24 KFH48005.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SapB_1 PF05184.15 KFH48005.1 - 0.006 16.6 0.4 0.046 13.7 0.0 2.6 2 0 0 2 2 2 1 Saposin-like type B, region 1 NPR3 PF03666.13 KFH48006.1 - 1.3 7.7 5.3 1.8 7.3 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HMG_box PF00505.19 KFH48007.1 - 6.3e-25 87.4 1.5 8.5e-25 87.0 1.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFH48007.1 - 7.3e-18 64.9 2.2 9.6e-18 64.6 2.2 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KFH48007.1 - 0.0016 19.0 1.0 0.0041 17.7 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KFH48007.1 - 0.013 15.5 0.4 0.025 14.5 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KFH48007.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Dpy-30 PF05186.13 KFH48008.1 - 6.9e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Tantalus PF15386.6 KFH48009.1 - 0.12 12.4 0.1 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Drosophila Tantalus-like ATP_bind_1 PF03029.17 KFH48010.1 - 6.1e-74 248.8 0.0 1.4e-73 247.6 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KFH48010.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KFH48010.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFH48010.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFH48010.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFH48010.1 - 0.014 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFH48010.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KFH48010.1 - 0.018 15.1 0.0 0.019 15.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KFH48010.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFH48010.1 - 0.03 14.2 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFH48010.1 - 0.042 14.4 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KFH48010.1 - 0.044 13.3 0.0 7.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KFH48010.1 - 0.058 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFH48010.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_10 PF12846.7 KFH48010.1 - 0.1 11.5 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 KFH48010.1 - 0.13 12.3 0.0 0.44 10.6 0.0 2.0 1 1 1 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFH48010.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DRMBL PF07522.14 KFH48012.1 - 9.7e-33 112.6 0.0 1.6e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KFH48012.1 - 1.6e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PGM_PMM_I PF02878.16 KFH48013.1 - 7e-34 116.5 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFH48013.1 - 1.7e-25 89.4 0.0 3.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFH48013.1 - 2.7e-16 60.0 0.0 5.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFH48013.1 - 1.2e-06 28.5 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GPI-anchored PF10342.9 KFH48014.1 - 1.6e-21 76.8 0.1 1.6e-21 76.8 0.1 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tmemb_cc2 PF10267.9 KFH48015.1 - 0.0059 15.8 0.8 0.0059 15.8 0.8 2.2 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein zf-RING_2 PF13639.6 KFH48016.1 - 0.0044 17.3 8.8 0.0044 17.3 8.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-ANAPC11 PF12861.7 KFH48016.1 - 0.96 9.5 7.8 0.26 11.4 3.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M76 PF09768.9 KFH48017.1 - 1.2e-69 233.5 1.9 1.4e-69 233.2 1.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KFH48017.1 - 0.011 15.6 2.4 0.013 15.4 0.9 1.7 1 1 0 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 KFH48017.1 - 0.034 14.4 0.1 0.049 14.0 0.1 1.3 1 0 0 1 1 1 0 Effector protein Cys_knot PF00007.22 KFH48017.1 - 0.036 14.3 1.6 1.1 9.5 0.5 2.3 2 0 0 2 2 2 0 Cystine-knot domain DUF1996 PF09362.10 KFH48018.1 - 1.2e-61 208.7 0.5 1.9e-61 208.0 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KFH48018.1 - 2.2e-17 63.0 7.4 4.7e-17 62.0 7.4 1.6 1 0 0 1 1 1 1 WSC domain Ndc1_Nup PF09531.10 KFH48018.1 - 1.2 7.8 2.0 1.5 7.5 2.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SARAF PF06682.12 KFH48019.1 - 3.3e-86 290.0 8.8 4.8e-85 286.1 8.8 1.9 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TauE PF01925.19 KFH48019.1 - 0.012 15.3 0.7 0.012 15.3 0.7 2.0 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF3262 PF11660.8 KFH48019.1 - 0.074 13.4 0.5 0.16 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Pex2_Pex12 PF04757.14 KFH48021.1 - 1.3e-42 145.9 3.8 1.7e-42 145.6 3.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KFH48021.1 - 3.8e-12 45.8 8.5 5.9e-12 45.2 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH48021.1 - 1.4e-11 44.5 8.7 2.1e-11 44.0 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFH48021.1 - 1.6e-10 40.6 6.3 2.5e-10 40.1 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH48021.1 - 5.8e-10 38.9 6.5 8.9e-10 38.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH48021.1 - 5.9e-08 32.6 7.0 1.1e-07 31.7 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH48021.1 - 2.3e-07 30.6 5.5 3.8e-07 30.0 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFH48021.1 - 2.6e-07 30.8 6.4 4.4e-07 30.1 6.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFH48021.1 - 6.7e-07 29.1 6.6 1.1e-06 28.4 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFH48021.1 - 1.1e-06 28.7 7.6 1.7e-06 28.1 7.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFH48021.1 - 0.00025 20.9 1.8 0.00044 20.1 1.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFH48021.1 - 0.00035 20.7 5.7 0.00059 19.9 5.7 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KFH48021.1 - 0.0032 17.2 1.1 0.0055 16.5 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KFH48021.1 - 0.044 13.8 2.4 0.075 13.1 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFH48021.1 - 0.068 13.0 6.7 0.15 11.9 6.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFH48021.1 - 0.16 11.8 3.3 0.33 10.7 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Hydrolase_4 PF12146.8 KFH48022.1 - 4.7e-15 55.5 0.0 8.9e-10 38.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFH48022.1 - 8.9e-10 38.6 0.1 3e-06 27.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH48022.1 - 3.8e-05 24.4 0.0 0.00011 22.9 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KFH48022.1 - 5.2e-05 22.1 0.0 0.099 11.3 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 KFH48022.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KFH48022.1 - 0.0007 19.3 0.0 0.0019 17.9 0.0 1.6 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFH48022.1 - 0.0019 17.7 0.0 0.014 14.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFH48022.1 - 0.0042 16.7 0.0 0.07 12.7 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KFH48022.1 - 0.0069 16.3 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KFH48022.1 - 0.2 11.5 0.0 0.58 10.0 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Glyco_hydro_53 PF07745.13 KFH48023.1 - 8.8e-103 343.9 0.0 1e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KFH48023.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4015 PF13200.6 KFH48023.1 - 0.059 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain MFS_1 PF07690.16 KFH48024.1 - 1.1e-37 129.8 41.8 1.1e-37 129.8 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48024.1 - 3.4e-08 32.8 2.2 3.4e-08 32.8 2.2 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter UCH PF00443.29 KFH48025.1 - 2.2e-35 122.4 0.0 2.1e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH48025.1 - 2.5e-06 27.3 3.1 0.035 13.7 1.6 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Glyoxal_oxid_N PF07250.11 KFH48026.1 - 5.5e-28 97.8 0.0 2.2e-27 95.8 0.0 1.9 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KFH48026.1 - 1.2e-21 76.8 0.0 2.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) WSC PF01822.19 KFH48026.1 - 2.2e-14 53.4 3.8 4.1e-14 52.5 3.8 1.4 1 0 0 1 1 1 1 WSC domain Rax2 PF12768.7 KFH48027.1 - 5.3e-76 254.8 0.1 3.6e-74 248.9 0.0 3.3 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Kelch_4 PF13418.6 KFH48027.1 - 0.029 14.4 0.1 0.65 10.1 0.0 3.2 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF5122 PF17164.4 KFH48027.1 - 0.1 12.9 16.2 15 6.0 0.0 8.1 10 0 0 10 10 10 0 Domain of unknown function (DUF5122) beta-propeller Kelch_1 PF01344.25 KFH48027.1 - 0.13 11.9 0.2 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Caps_synth PF05704.12 KFH48028.1 - 9.6e-14 51.4 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KFH48028.1 - 1.7e-06 28.6 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFH48028.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Efg1 PF10153.9 KFH48029.1 - 2.3e-33 114.9 8.0 5.4e-33 113.7 8.0 1.6 1 0 0 1 1 1 1 rRNA-processing protein Efg1 LRV_FeS PF05484.11 KFH48029.1 - 0.087 12.8 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 LRV protein FeS4 cluster Ribosomal_S19 PF00203.21 KFH48030.1 - 3e-33 113.6 0.2 3.9e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KFH48030.1 - 0.043 13.5 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase FAD_binding_6 PF00970.24 KFH48032.1 - 2.1e-30 105.0 0.0 3.3e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFH48032.1 - 1.1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFH48032.1 - 0.00026 21.2 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain ATG11 PF10377.9 KFH48034.1 - 1.2e-43 148.2 0.7 1.2e-43 148.2 0.7 4.0 3 1 2 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 KFH48034.1 - 5.6e-05 22.4 8.5 5.6e-05 22.4 8.5 6.3 2 2 3 5 5 5 1 Autophagy protein Apg17 Cleaved_Adhesin PF07675.11 KFH48034.1 - 7.6e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Cleaved Adhesin Domain FERM_f0 PF16511.5 KFH48034.1 - 0.0091 16.3 0.3 1.4 9.3 0.1 2.8 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM P34-Arc PF04045.14 KFH48035.1 - 3.4e-99 331.4 0.4 5e-99 330.9 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc MaoC_dehydratas PF01575.19 KFH48036.1 - 1.2e-19 70.1 0.0 1.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFH48036.1 - 0.014 15.5 0.0 8.6 6.5 0.0 2.6 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KFH48036.1 - 0.035 14.5 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Iwr1 PF08574.10 KFH48037.1 - 1.4e-06 29.2 0.8 1.4e-06 29.2 0.8 3.9 4 1 0 4 4 4 2 Transcription factor Iwr1 DUF3453 PF11935.8 KFH48038.1 - 1.9e-67 227.2 0.0 1.2e-66 224.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) CH PF00307.31 KFH48039.1 - 3.1e-13 49.9 0.0 4.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain K_channel_TID PF07941.11 KFH48039.1 - 0.024 15.1 3.8 0.024 15.1 3.8 5.3 5 1 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain CAMSAP_CH PF11971.8 KFH48039.1 - 0.23 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain TTKRSYEDQ PF10212.9 KFH48039.1 - 5 6.0 11.7 7 5.5 11.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Complex1_49kDa PF00346.19 KFH48040.1 - 6.3e-124 412.5 0.0 8.7e-124 412.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KFH48040.1 - 0.0039 16.2 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RRM_1 PF00076.22 KFH48041.1 - 5e-25 87.1 0.4 8.9e-11 41.5 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.22 KFH48042.1 - 1.8e-20 73.5 0.0 2.4e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 KFH48043.1 - 6.5e-14 51.5 0.1 2.2e-09 37.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glypican PF01153.19 KFH48043.1 - 8.6 5.1 6.3 14 4.4 6.3 1.2 1 0 0 1 1 1 0 Glypican Acetyltransf_3 PF13302.7 KFH48044.1 - 2.3e-26 93.1 0.0 2.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH48044.1 - 3.8e-08 33.6 0.0 5.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KFH48044.1 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATG101 PF07855.12 KFH48045.1 - 2.6e-52 176.9 0.0 3.4e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 KFH48045.1 - 0.5 10.4 3.7 0.88 9.6 2.6 1.8 1 1 1 2 2 2 0 Mo-co oxidoreductase dimerisation domain LSM PF01423.22 KFH48046.1 - 8.9e-19 67.0 0.7 1.1e-18 66.6 0.7 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFH48046.1 - 0.032 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KFH48046.1 - 0.034 14.3 0.1 0.042 14.0 0.1 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain KH_1 PF00013.29 KFH48049.1 - 1.7e-40 136.7 10.4 8e-16 57.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFH48049.1 - 1.4e-09 37.6 9.2 0.012 15.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFH48049.1 - 1.7e-07 31.0 3.8 0.062 13.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFH48049.1 - 0.00014 21.8 6.3 0.24 11.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain EF-hand_4 PF12763.7 KFH48050.1 - 6.8e-26 90.2 0.0 5e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KFH48050.1 - 1.3e-05 24.9 1.3 0.00086 19.1 0.2 2.9 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 KFH48050.1 - 9.5e-05 22.7 70.0 0.00056 20.3 45.7 6.4 6 2 0 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KFH48050.1 - 0.0079 16.6 1.0 0.67 10.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFH48050.1 - 0.029 14.3 0.1 6.1 7.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain E3_binding PF02817.17 KFH48050.1 - 0.035 14.5 0.0 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 e3 binding domain CAP_GLY PF01302.25 KFH48051.1 - 6.5e-14 51.7 0.2 2.2e-13 50.0 0.2 1.9 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 KFH48051.1 - 6e-11 42.4 6.2 0.077 13.4 0.1 5.0 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH48051.1 - 1.9e-10 40.3 2.9 0.0063 16.3 1.2 4.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFH48051.1 - 1.9e-05 24.4 9.2 7.2 6.9 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KFH48051.1 - 2.8e-05 23.7 0.0 0.00031 20.3 0.0 2.4 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KFH48051.1 - 0.015 15.7 3.1 1.2e+02 3.9 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat HEPN_SAV2148 PF18725.1 KFH48051.1 - 0.059 12.8 0.1 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 SAV2148-like HEPN DEAD PF00270.29 KFH48052.1 - 1.5e-30 106.3 0.0 2.9e-30 105.3 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH48052.1 - 7.8e-21 74.5 0.2 6.6e-20 71.5 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48052.1 - 4.6e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit APH PF01636.23 KFH48053.1 - 1e-41 143.5 0.0 1.4e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFH48053.1 - 4.3e-06 26.3 0.0 1.6e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFH48053.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFH48053.1 - 0.00023 20.6 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.14 KFH48053.1 - 0.00092 18.5 0.0 0.0042 16.3 0.0 1.8 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 KFH48053.1 - 0.0017 18.0 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFH48053.1 - 0.075 12.4 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KFH48053.1 - 0.14 11.0 0.1 0.55 9.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) HEAT_2 PF13646.6 KFH48054.1 - 9.8e-05 22.7 3.1 0.059 13.8 0.3 4.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KFH48054.1 - 0.00062 19.8 2.4 0.19 12.1 0.0 4.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KFH48054.1 - 0.0012 18.9 0.3 9.7 6.2 0.0 4.9 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFH48054.1 - 0.0077 16.7 2.0 0.1 13.1 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat NopRA1 PF16201.5 KFH48054.1 - 0.072 12.7 0.0 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 SWIRM-assoc_2 PF16496.5 KFH48054.1 - 0.35 9.7 11.2 0.71 8.7 11.2 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Nitr_red_assoc PF09655.10 KFH48054.1 - 1.2 9.8 3.6 26 5.4 0.0 3.2 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DSPc PF00782.20 KFH48055.1 - 1.2e-24 86.6 0.0 5e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFH48055.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Mt_ATP-synt_B PF05405.14 KFH48056.1 - 4.9e-53 179.1 8.0 6.5e-53 178.7 8.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 KFH48056.1 - 0.1 12.7 3.1 0.058 13.5 1.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NPV_P10 PF05531.12 KFH48056.1 - 0.47 11.0 6.0 5.4 7.6 6.0 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cullin PF00888.22 KFH48057.1 - 4.9e-200 666.3 0.7 6.2e-200 665.9 0.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFH48057.1 - 3.8e-26 90.9 0.3 1.2e-25 89.3 0.3 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DFF-C PF09033.10 KFH48057.1 - 0.028 14.3 0.3 0.088 12.7 0.3 1.8 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain YpjP PF14005.6 KFH48057.1 - 0.063 13.3 3.2 0.16 12.0 0.0 3.0 3 0 0 3 3 3 0 YpjP-like protein Ctr PF04145.15 KFH48059.1 - 3.9e-32 111.9 11.6 1.1e-31 110.4 11.6 1.6 1 1 0 1 1 1 1 Ctr copper transporter family LPG_synthase_TM PF03706.13 KFH48059.1 - 0.03 13.9 6.7 0.036 13.6 6.7 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Sigma_1s PF02454.16 KFH48059.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma 1s protein DUF962 PF06127.11 KFH48059.1 - 0.13 12.3 2.3 0.44 10.7 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) mRNA_cap_enzyme PF01331.19 KFH48061.1 - 1.2e-54 185.1 0.1 1.7e-54 184.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFH48061.1 - 1.8e-31 109.0 0.0 3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KFH48061.1 - 3.4e-07 30.1 0.0 0.00011 21.9 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KFH48061.1 - 0.0053 17.1 0.0 0.008 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Pkinase PF00069.25 KFH48062.1 - 1.9e-69 234.0 0.0 2.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48062.1 - 2.3e-42 145.0 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48062.1 - 2.7e-05 23.6 0.0 6.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFH48062.1 - 0.0019 17.6 0.2 0.0033 16.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFH48062.1 - 0.053 13.1 0.3 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFH48062.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KFH48062.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Levi_coat PF01819.17 KFH48062.1 - 0.082 12.9 1.0 2.2 8.3 0.9 2.3 2 0 0 2 2 2 0 Levivirus coat protein Haspin_kinase PF12330.8 KFH48062.1 - 0.085 11.8 0.9 0.14 11.1 0.9 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFH48062.1 - 0.76 8.5 3.9 1.6 7.4 3.9 1.5 1 1 0 1 1 1 0 Fungal protein kinase Sybindin PF04099.12 KFH48064.1 - 3.1e-16 59.6 0.0 2.5e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family AA_kinase PF00696.28 KFH48065.1 - 4.9e-38 131.1 1.4 6.5e-38 130.7 1.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFH48065.1 - 8.9e-17 60.8 1.4 3e-16 59.2 0.1 2.3 2 0 0 2 2 2 1 PUA domain MTS PF05175.14 KFH48066.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain MSC PF09402.10 KFH48067.1 - 1.1e-115 386.8 0.0 1.5e-115 386.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KFH48067.1 - 3.1e-16 58.8 0.0 5.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KFH48067.1 - 0.0017 17.9 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 Thymopoietin protein RabGAP-TBC PF00566.18 KFH48068.1 - 6.4e-28 97.9 2.0 2.1e-27 96.2 2.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-bind_7 PF15963.5 KFH48069.1 - 7.8e-25 86.6 0.5 7.8e-25 86.6 0.5 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFH48069.1 - 2.5e-06 27.6 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH48069.1 - 0.0019 18.4 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain CBFB_NFYA PF02045.15 KFH48070.1 - 3e-28 98.2 5.3 6e-28 97.2 5.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KFH48070.1 - 0.051 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein SF3b1 PF08920.10 KFH48071.1 - 7.9e-27 94.1 7.5 7.9e-27 94.1 7.5 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KFH48071.1 - 1.2e-13 51.2 0.8 0.016 15.7 0.0 8.4 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KFH48071.1 - 3.3e-12 46.6 4.9 0.1 13.0 0.1 7.6 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 KFH48071.1 - 1.1e-09 37.7 8.1 0.81 10.1 0.0 9.0 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 KFH48071.1 - 2.3e-06 27.7 1.5 1.3 9.0 0.0 6.3 6 2 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFH48071.1 - 1.2e-05 25.8 0.2 1.1 9.9 0.0 5.5 6 0 0 6 6 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFH48071.1 - 1.3e-05 24.0 0.6 0.0033 16.1 0.1 3.2 2 2 1 3 3 3 1 Adaptin N terminal region DUF3385 PF11865.8 KFH48071.1 - 6.4e-05 22.9 1.6 0.0033 17.3 0.0 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KFH48071.1 - 0.00012 21.9 0.3 0.95 9.1 0.0 4.3 5 0 0 5 5 5 2 NUC173 domain Dopey_N PF04118.14 KFH48071.1 - 0.0012 18.0 0.5 11 5.0 0.0 4.6 5 0 0 5 5 5 1 Dopey, N-terminal UNC45-central PF11701.8 KFH48071.1 - 0.0021 18.1 0.0 0.0069 16.4 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KFH48071.1 - 0.012 15.2 0.1 1.9 8.0 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 KFH48071.1 - 0.022 13.1 0.3 4.5 5.4 0.0 3.8 2 1 2 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 KFH48071.1 - 0.13 11.3 0.0 7.3 5.6 0.0 3.2 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Nore1-SARAH PF16517.5 KFH48071.1 - 2.3 8.2 4.9 9.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain NUDIX PF00293.28 KFH48075.1 - 1.2e-08 35.1 0.0 2.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Hyccin PF09790.9 KFH48075.1 - 0.028 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Hyccin CPSase_L_D2 PF02786.17 KFH48076.1 - 5.7e-81 271.0 0.1 8.7e-81 270.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KFH48076.1 - 8e-68 228.1 0.0 1.3e-67 227.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KFH48076.1 - 1.3e-38 131.9 0.0 2.7e-38 130.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 KFH48076.1 - 1.1e-26 94.0 0.0 2.2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 KFH48076.1 - 3.9e-21 75.2 0.0 2.4e-10 40.5 0.0 3.1 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFH48076.1 - 1.3e-18 66.6 2.8 1.8e-18 66.1 1.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFH48076.1 - 1.5e-11 44.0 0.5 1.7e-06 27.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KFH48076.1 - 2.5e-09 37.0 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFH48076.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KFH48076.1 - 4.4e-05 22.8 0.1 0.013 14.8 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KFH48076.1 - 7e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KFH48076.1 - 0.00017 22.2 0.1 0.63 10.8 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.11 KFH48076.1 - 0.00037 20.1 0.0 0.0016 18.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KFH48076.1 - 0.0027 17.3 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain NQRA PF05896.11 KFH48076.1 - 0.0044 16.5 0.2 0.0076 15.7 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 KFH48076.1 - 0.012 15.6 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 KFH48076.1 - 0.044 13.7 0.3 0.12 12.4 0.3 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 KFH48076.1 - 0.054 12.7 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KFH48076.1 - 0.068 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.6 KFH48076.1 - 0.18 11.0 0.0 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp GCV_H PF01597.19 KFH48076.1 - 0.21 11.5 0.2 0.68 9.8 0.1 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein ThiF PF00899.21 KFH48077.1 - 3.8e-64 216.4 0.0 5.4e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFH48077.1 - 3.2e-26 91.3 0.0 5.3e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KFH48077.1 - 6.2e-05 23.1 0.6 0.00023 21.3 0.1 2.2 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFH48077.1 - 0.059 13.6 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UAE_UbL PF14732.6 KFH48077.1 - 0.098 13.3 0.0 0.38 11.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.27 KFH48077.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH48077.1 - 0.17 11.8 0.3 7.7 6.5 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding UBA_e1_thiolCys PF10585.9 KFH48077.1 - 0.22 11.4 0.9 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site MFS_1 PF07690.16 KFH48078.1 - 5.4e-31 107.8 33.0 8e-31 107.2 33.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48078.1 - 2.2e-11 43.3 4.0 2.2e-11 43.3 4.0 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 KFH48078.1 - 0.00031 19.7 0.9 0.00069 18.6 0.9 1.6 1 0 0 1 1 1 1 POT family Gly-zipper_YMGG PF13441.6 KFH48078.1 - 1.8 8.4 8.1 1.5 8.6 3.2 3.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KFH48078.1 - 8.1 6.5 10.3 4.3 7.4 4.9 3.2 2 1 0 2 2 2 0 Glycine zipper Podoplanin PF05808.11 KFH48079.1 - 0.0083 16.2 1.4 0.014 15.5 1.4 1.3 1 0 0 1 1 1 1 Podoplanin Trp_oprn_chp PF09534.10 KFH48079.1 - 0.013 15.3 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3318 PF11780.8 KFH48079.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) S-AdoMet_synt_C PF02773.16 KFH48080.1 - 2.8e-65 218.5 1.0 3.2e-65 218.3 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFH48080.1 - 2.4e-45 153.6 0.0 4.9e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFH48080.1 - 1.1e-43 148.0 0.8 1.8e-43 147.2 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Sel1 PF08238.12 KFH48081.1 - 3.6e-11 43.3 6.1 0.008 16.8 0.4 3.9 4 0 0 4 4 4 3 Sel1 repeat HGTP_anticodon PF03129.20 KFH48083.1 - 7e-23 80.6 0.4 6.1e-22 77.6 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFH48083.1 - 2e-08 34.4 0.0 9.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) TFIIA PF03153.13 KFH48084.1 - 0.00017 21.7 6.2 0.00019 21.6 6.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit G10 PF01125.17 KFH48085.1 - 4.2e-63 211.5 7.0 4.7e-63 211.3 7.0 1.0 1 0 0 1 1 1 1 G10 protein DUF1257 PF06868.11 KFH48085.1 - 0.12 12.7 1.0 0.19 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) PTS_2-RNA PF01885.16 KFH48087.1 - 1e-63 214.7 0.0 1.2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CSTF2_hinge PF14327.6 KFH48088.1 - 1.7e-31 108.5 2.5 3.3e-31 107.6 2.5 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KFH48088.1 - 1.2e-21 76.3 0.0 2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KFH48088.1 - 7.4e-12 44.7 7.8 7.4e-12 44.7 7.8 3.4 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KFH48088.1 - 0.037 14.1 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 KFH48088.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_5 PF13893.6 KFH48088.1 - 0.2 11.2 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KFH48089.1 - 0.00013 22.2 0.0 0.00047 20.4 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 KFH48089.1 - 0.00099 19.9 20.6 0.00099 19.9 20.6 8.2 3 1 2 5 5 5 1 Nucleoporin FG repeat region NUP214 PF16755.5 KFH48089.1 - 0.025 13.8 0.0 0.062 12.5 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40 PF00400.32 KFH48089.1 - 0.1 13.5 0.9 0.96 10.4 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Pox_Ag35 PF03286.14 KFH48089.1 - 2.4 7.9 9.3 0.41 10.4 4.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BSP_II PF05432.11 KFH48089.1 - 9.8 5.8 15.9 0.34 10.6 8.1 2.4 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.25 KFH48091.1 - 7.3e-67 225.5 0.0 1.5e-66 224.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48091.1 - 4.2e-36 124.6 0.0 7.1e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48091.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFH48091.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFH48091.1 - 0.036 14.0 1.6 0.055 13.4 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFH48091.1 - 0.082 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Apq12 PF12716.7 KFH48092.1 - 9.5e-12 44.7 17.9 1.9e-11 43.7 17.9 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Rhomboid PF01694.22 KFH48092.1 - 0.14 12.1 6.7 0.12 12.4 5.8 1.4 1 1 0 1 1 1 0 Rhomboid family HEPN_AbiA_CTD PF18732.1 KFH48093.1 - 0.23 11.4 0.0 0.27 11.2 0.0 1.1 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain PHD PF00628.29 KFH48094.1 - 1.6e-12 47.1 19.4 8.5e-08 32.0 10.3 2.6 2 1 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KFH48094.1 - 0.0041 17.0 7.5 0.58 10.1 0.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFH48094.1 - 0.036 13.6 13.2 0.12 11.9 3.8 3.1 3 0 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 KFH48094.1 - 0.037 13.6 6.0 0.9 9.1 1.9 2.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 KFH48094.1 - 3.2 7.9 9.6 7 6.8 2.9 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger MPC PF03650.13 KFH48095.1 - 4.7e-33 113.6 0.0 6.3e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers adh_short_C2 PF13561.6 KFH48096.1 - 3.1e-39 134.9 0.1 3.8e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH48096.1 - 1.8e-34 118.9 0.2 2.2e-34 118.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH48096.1 - 6.4e-12 45.7 0.1 9.3e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH48096.1 - 0.0029 17.1 0.0 0.0099 15.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFH48096.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PDZ PF00595.24 KFH48096.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RNase_T PF00929.24 KFH48097.1 - 3.2e-25 89.6 0.0 3.7e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease VRR_NUC PF08774.11 KFH48098.1 - 2.8e-21 75.6 0.0 8.1e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Pyrid_ox_like PF16242.5 KFH48098.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like RHH_1 PF01402.21 KFH48098.1 - 0.046 13.7 0.4 0.2 11.6 0.4 2.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family U3_snoRNA_assoc PF08297.11 KFH48098.1 - 1 10.1 0.0 1 10.1 0.0 2.7 3 0 0 3 3 3 0 U3 snoRNA associated THF_DHG_CYH PF00763.23 KFH48100.1 - 1.8e-26 92.7 0.1 2.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KFH48100.1 - 1.9e-14 53.3 0.0 6.2e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MTS PF05175.14 KFH48100.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Saf_2TM PF18303.1 KFH48101.1 - 0.12 12.0 0.9 0.72 9.4 0.7 1.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain FAA_hydrolase PF01557.18 KFH48102.1 - 1.8e-53 181.4 0.0 2.2e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family WD40 PF00400.32 KFH48103.1 - 1.5e-59 196.5 17.1 2.2e-10 40.9 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48103.1 - 2.9e-23 82.0 0.0 0.00049 20.3 0.0 6.2 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH48103.1 - 1.1e-08 35.2 0.0 5.5e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFH48103.1 - 3.5e-08 32.5 1.2 0.052 12.2 0.2 4.5 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFH48103.1 - 5e-08 32.3 0.2 0.92 8.4 0.0 5.3 2 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KFH48103.1 - 7.7e-06 25.2 1.8 0.8 8.7 0.1 4.2 2 1 2 4 4 4 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 KFH48103.1 - 0.00011 21.6 0.0 0.098 12.0 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 KFH48103.1 - 0.00014 20.8 0.1 0.24 10.1 0.0 3.7 2 2 1 4 4 4 1 Nup133 N terminal like Frtz PF11768.8 KFH48103.1 - 0.0026 16.1 0.0 0.26 9.5 0.0 2.4 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KFH48103.1 - 0.0057 15.8 0.0 0.65 9.0 0.0 3.2 1 1 3 4 4 4 1 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 KFH48103.1 - 0.049 12.5 0.9 5.8 5.7 0.0 2.9 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain NHL PF01436.21 KFH48103.1 - 0.14 12.3 1.1 16 5.8 0.3 3.7 4 0 0 4 4 4 0 NHL repeat zinc_ribbon_16 PF17034.5 KFH48104.1 - 6e-18 65.2 7.4 1.1e-17 64.4 7.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KFH48104.1 - 1.6e-06 27.7 4.3 1.6e-06 27.7 4.3 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-FPG_IleRS PF06827.14 KFH48104.1 - 0.56 10.1 6.7 1 9.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Methyltr_RsmB-F PF01189.17 KFH48106.1 - 4.5e-16 59.1 0.0 1.3e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Pkinase PF00069.25 KFH48107.1 - 1.9e-69 234.0 2.4 1.6e-68 231.0 2.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48107.1 - 7.6e-53 179.4 0.1 1.4e-52 178.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFH48107.1 - 6.6e-23 80.8 0.0 2e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFH48107.1 - 3e-06 26.8 0.0 5.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KFH48107.1 - 1.2e-05 25.7 0.2 6.5e-05 23.3 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 KFH48107.1 - 2.6e-05 23.2 0.0 2.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFH48107.1 - 0.0012 17.8 0.6 0.0012 17.8 0.6 2.3 2 1 0 2 2 2 1 Haspin like kinase domain PH PF00169.29 KFH48107.1 - 0.0036 17.8 0.1 0.0088 16.5 0.1 1.7 1 0 0 1 1 1 1 PH domain APH PF01636.23 KFH48107.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFH48107.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DDRGK PF09756.9 KFH48107.1 - 0.7 9.5 14.5 1.8 8.1 14.5 1.6 1 0 0 1 1 1 0 DDRGK domain CENP-H PF05837.12 KFH48108.1 - 8.8e-33 113.1 0.6 8.8e-33 113.1 0.6 2.5 2 1 0 2 2 2 1 Centromere protein H (CENP-H) RRN9 PF10680.9 KFH48108.1 - 0.11 12.8 0.2 0.38 11.1 0.2 1.9 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor DUF2868 PF11067.8 KFH48108.1 - 0.42 10.1 3.3 0.58 9.6 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Cnn_1N PF07989.11 KFH48108.1 - 1.1 9.4 7.8 3.4 7.9 0.3 3.1 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KFH48108.1 - 6.2 7.1 11.3 3.2 8.0 3.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding MFS_1 PF07690.16 KFH48109.1 - 9.7e-29 100.4 15.9 1.3e-28 99.9 15.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 KFH48111.1 - 2e-05 24.1 0.5 0.0004 19.8 0.0 2.3 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) Transgly_assoc PF04226.13 KFH48111.1 - 0.038 14.2 0.6 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein DUF1656 PF07869.12 KFH48111.1 - 0.14 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Tubulin PF00091.25 KFH48112.1 - 6.3e-65 219.1 0.0 8.8e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFH48112.1 - 8.9e-45 151.9 0.0 1.4e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFH48112.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Zn_clus PF00172.18 KFH48113.1 - 2.2e-07 30.9 9.5 3.7e-07 30.1 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 KFH48113.1 - 1.5 9.2 4.2 11 6.4 4.9 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF4140 PF13600.6 KFH48114.1 - 0.14 12.6 1.8 0.26 11.7 1.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KFH48114.1 - 0.15 11.1 2.1 0.24 10.4 2.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-H2C2_2 PF13465.6 KFH48116.1 - 6.7e-09 35.8 18.5 4.7e-05 23.6 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFH48116.1 - 2e-07 31.1 11.5 2.2e-05 24.7 4.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KFH48116.1 - 6.5e-06 26.3 1.3 1.8e-05 25.0 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFH48116.1 - 5.6e-05 23.0 8.7 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFH48116.1 - 0.00018 22.1 19.0 0.0013 19.4 3.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFH48116.1 - 0.00053 20.2 4.2 0.00074 19.7 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFH48116.1 - 0.041 14.2 2.4 0.054 13.8 1.3 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFH48116.1 - 0.099 12.4 7.4 2.1 8.2 0.6 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFH48116.1 - 0.62 10.0 4.8 12 5.9 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Arginosuc_synth PF00764.19 KFH48117.1 - 3.3e-146 487.6 0.0 3.7e-146 487.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFH48117.1 - 0.022 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TPR_3 PF07720.12 KFH48117.1 - 0.038 14.0 0.2 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA_Me_trans PF03054.16 KFH48117.1 - 0.049 12.4 0.1 0.12 11.1 0.1 1.6 1 0 0 1 1 1 0 tRNA methyl transferase TPR_2 PF07719.17 KFH48120.1 - 1.4e-30 102.9 32.4 0.00031 20.6 0.1 13.0 13 0 0 13 13 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 KFH48120.1 - 2.3e-30 103.1 29.8 9.9e-06 25.2 0.2 12.3 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48120.1 - 1.1e-24 84.6 23.2 0.00027 20.9 0.1 12.5 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFH48120.1 - 3.1e-18 64.4 13.4 0.0003 20.6 0.1 10.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFH48120.1 - 1.3e-16 60.7 23.5 1.6e-05 25.1 2.1 10.2 6 3 3 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFH48120.1 - 4.3e-16 58.2 37.4 0.035 14.9 0.0 13.3 13 2 2 15 15 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFH48120.1 - 3e-14 53.3 26.4 0.026 15.0 0.0 10.7 8 2 3 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 KFH48120.1 - 3.6e-13 48.9 7.0 0.51 10.8 0.1 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFH48120.1 - 2.3e-12 47.3 30.2 6.4e-06 26.7 0.3 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFH48120.1 - 1.2e-10 41.3 22.9 0.018 15.6 0.0 11.4 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFH48120.1 - 1.6e-08 34.1 29.2 0.0062 16.4 0.1 10.3 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFH48120.1 - 4.3e-08 32.7 16.4 0.28 10.9 0.1 9.5 9 0 0 9 9 9 2 TPR repeat PPR PF01535.20 KFH48120.1 - 0.02 15.1 0.0 7.6 7.0 0.0 4.2 2 0 0 2 2 2 0 PPR repeat ANAPC3 PF12895.7 KFH48120.1 - 0.027 14.7 19.3 0.82 9.9 0.2 6.9 8 1 1 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 NDUFA12 PF05071.16 KFH48121.1 - 4.6e-11 43.4 0.2 4.6e-11 43.4 0.2 2.3 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 FAD_binding_3 PF01494.19 KFH48122.1 - 2.7e-28 99.3 0.2 6.5e-27 94.7 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KFH48122.1 - 1.3e-05 24.4 0.5 0.0025 16.9 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 KFH48122.1 - 0.00022 20.9 0.8 0.37 10.3 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH48122.1 - 0.00059 19.2 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KFH48122.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KFH48122.1 - 0.076 11.9 0.1 1.6 7.5 0.0 2.5 2 1 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KFH48122.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KFH48122.1 - 0.092 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SNase PF00565.17 KFH48123.1 - 1.5e-24 86.6 0.1 2.1e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue LRR_6 PF13516.6 KFH48125.1 - 1e-14 53.3 0.1 0.00063 19.6 0.0 6.4 7 0 0 7 7 7 3 Leucine Rich repeat F-box-like PF12937.7 KFH48125.1 - 2.4e-11 43.3 0.2 7.7e-11 41.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH48125.1 - 8.3e-09 35.1 0.1 2.8e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KFH48125.1 - 1.7e-06 28.3 2.3 0.28 11.7 0.0 5.3 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFH48125.1 - 4.5e-05 23.4 3.2 0.11 13.1 0.1 5.7 6 0 0 6 6 6 1 Leucine Rich Repeat PRANC PF09372.10 KFH48125.1 - 0.0091 16.3 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 PRANC domain F-box_4 PF15966.5 KFH48125.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 F-box 3-HAO PF06052.12 KFH48127.1 - 4.9e-64 214.5 0.0 5.6e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KFH48127.1 - 2.6e-06 27.0 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFH48127.1 - 0.00053 19.6 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFH48127.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 KFH48127.1 - 0.033 14.4 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 KFH48127.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein DZR PF12773.7 KFH48127.1 - 0.23 11.5 1.8 0.64 10.1 1.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon SET PF00856.28 KFH48128.1 - 8.7e-09 36.0 0.0 5.3e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 SET domain BTB_2 PF02214.22 KFH48129.1 - 2.5e-08 34.2 0.1 5.9e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_S13_N PF08069.12 KFH48130.1 - 1.5e-30 105.0 0.1 2.7e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFH48130.1 - 1.6e-15 57.0 0.2 2.5e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFH48130.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Forkhead PF00250.18 KFH48131.1 - 1.7e-33 114.7 0.0 3.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Amastin PF07344.11 KFH48132.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3040 PF11239.8 KFH48132.1 - 0.041 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Sds3 PF08598.11 KFH48133.1 - 3.8e-12 46.7 6.1 3.8e-12 46.7 6.1 2.8 1 1 1 2 2 2 1 Sds3-like AbiH PF14253.6 KFH48133.1 - 0.2 11.5 1.9 0.37 10.6 1.9 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH WD40 PF00400.32 KFH48134.1 - 4.4e-51 169.7 24.6 6.6e-07 29.9 0.2 11.5 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48134.1 - 1.3e-19 70.3 6.5 0.0095 16.2 0.1 9.0 4 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFH48134.1 - 3.4e-19 69.1 0.3 6.2e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFH48134.1 - 1.6e-08 33.9 0.7 0.18 10.7 0.0 4.4 4 2 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFH48134.1 - 3.7e-05 23.2 0.0 5.7 6.2 0.0 4.1 4 0 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 KFH48134.1 - 0.00023 20.0 0.2 0.14 10.8 0.1 3.9 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Frtz PF11768.8 KFH48134.1 - 0.029 12.7 0.0 2.6 6.2 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KFH48134.1 - 0.04 13.8 0.4 2.2 8.1 0.0 3.6 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFH48134.1 - 0.046 12.5 4.8 3.8 6.2 0.1 4.2 3 1 2 5 5 5 0 Nup133 N terminal like Hira PF07569.11 KFH48134.1 - 0.38 10.4 1.9 2.7 7.6 0.0 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split MAS20 PF02064.15 KFH48134.1 - 1.4 9.0 3.6 2.2 8.4 1.4 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor SNF5 PF04855.12 KFH48136.1 - 7e-66 222.4 2.0 3.8e-65 220.0 0.2 2.6 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Synaphin PF05835.12 KFH48136.1 - 0.65 10.3 0.0 0.65 10.3 0.0 3.1 3 0 0 3 3 3 0 Synaphin protein Totivirus_coat PF05518.11 KFH48136.1 - 4 5.4 13.6 6.9 4.6 13.6 1.3 1 0 0 1 1 1 0 Totivirus coat protein OGG_N PF07934.12 KFH48137.1 - 1.6e-18 66.9 0.0 3.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KFH48137.1 - 1.8e-15 57.3 0.0 2.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFH48137.1 - 7.8e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif LRR_4 PF12799.7 KFH48138.1 - 0.037 14.5 9.7 5.3 7.6 0.3 5.4 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) HupH_C PF04809.13 KFH48138.1 - 0.064 13.0 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region RR_TM4-6 PF06459.12 KFH48139.1 - 0.67 9.7 14.4 0.11 12.3 10.7 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1943 PF09172.11 KFH48139.1 - 5.6 6.1 5.7 8.3 5.5 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Vfa1 PF08432.10 KFH48139.1 - 9 6.6 18.6 18 5.6 18.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AMPK1_CBM PF16561.5 KFH48140.1 - 7.4e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MaoC_dehydratas PF01575.19 KFH48142.1 - 1.7e-23 82.5 0.0 3.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFH48142.1 - 6.4e-07 29.6 0.0 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF5102 PF17104.5 KFH48143.1 - 1.6e-05 25.1 4.2 0.033 14.2 1.8 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) RNA_pol_L_2 PF13656.6 KFH48144.1 - 2.2e-31 107.4 0.0 2.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFH48144.1 - 5.3e-11 41.8 0.0 7.6e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Roughex PF06020.11 KFH48144.1 - 0.38 9.8 3.6 0.49 9.4 3.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RNA_pol_Rpo13 PF12136.8 KFH48144.1 - 0.69 9.9 7.1 1.4 8.9 7.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CBF PF03914.17 KFH48145.1 - 3.6e-35 121.5 1.1 1.6e-34 119.4 0.2 2.5 2 1 1 3 3 3 1 CBF/Mak21 family Pkinase PF00069.25 KFH48146.1 - 2.1e-55 187.9 0.0 1.2e-50 172.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48146.1 - 3.6e-33 115.0 0.0 4.2e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48146.1 - 7.3e-07 28.8 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH48146.1 - 0.0015 18.5 4.0 0.0037 17.2 0.4 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH48146.1 - 0.0026 16.6 0.0 0.0059 15.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FliT PF05400.13 KFH48146.1 - 0.59 11.0 8.3 3.8 8.4 0.5 3.3 3 0 0 3 3 3 0 Flagellar protein FliT HTH_31 PF13560.6 KFH48147.1 - 0.064 13.6 0.1 0.098 13.0 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Git3 PF11710.8 KFH48148.1 - 5.3e-18 65.5 4.6 5.3e-18 65.5 4.6 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KFH48148.1 - 2.9e-09 36.6 12.1 6.5e-09 35.5 9.4 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KFH48148.1 - 1.7e-06 27.4 9.2 2.8e-06 26.7 9.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KFH48148.1 - 0.88 9.7 4.4 0.22 11.6 0.3 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term TIP41 PF04176.13 KFH48149.1 - 2.7e-67 225.5 0.1 3.5e-67 225.2 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family DUF3446 PF11928.8 KFH48149.1 - 3 8.2 9.2 5.4 7.4 9.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain UAA PF08449.11 KFH48150.1 - 4.5e-43 147.6 4.9 6.1e-43 147.1 4.9 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFH48150.1 - 4.7e-08 33.3 23.6 2.9e-06 27.5 5.4 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KFH48150.1 - 2.1e-05 23.8 0.3 0.16 11.1 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KFH48150.1 - 0.029 13.7 8.5 0.61 9.4 1.2 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 KFH48150.1 - 0.035 13.0 3.9 2.5 7.0 1.2 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like LSM PF01423.22 KFH48151.1 - 9.5e-18 63.7 0.0 1.2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFH48151.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 KFH48151.1 - 0.025 15.2 2.4 0.036 14.7 2.4 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Nop14 PF04147.12 KFH48152.1 - 1.5 6.9 36.0 2.1 6.5 36.0 1.1 1 0 0 1 1 1 0 Nop14-like family Mucin PF01456.17 KFH48152.1 - 3.1 7.8 10.1 8.5 6.4 10.1 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein PX PF00787.24 KFH48153.1 - 1.4e-18 66.9 0.0 6e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFH48153.1 - 2.6e-11 43.5 8.3 2.6e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like SET PF00856.28 KFH48154.1 - 1.7e-06 28.5 0.9 2.7e-06 27.9 0.9 1.4 1 0 0 1 1 1 1 SET domain Pkinase PF00069.25 KFH48155.1 - 7.1e-50 169.8 0.0 9.8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48155.1 - 4.7e-28 98.2 0.0 6.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48155.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFH48155.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH48155.1 - 0.028 14.3 0.5 1.2 9.0 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-LYAR PF08790.11 KFH48156.1 - 1.9e-14 53.3 3.6 1.9e-14 53.3 3.6 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3810 PF12725.7 KFH48157.1 - 0.0075 15.6 0.2 0.015 14.6 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) PKD_channel PF08016.12 KFH48158.1 - 0.006 15.3 6.2 0.13 10.9 1.1 2.2 2 0 0 2 2 2 2 Polycystin cation channel PSRT PF07636.11 KFH48158.1 - 0.017 14.8 0.4 0.017 14.8 0.4 1.8 2 0 0 2 2 2 0 PSRT BRE1 PF08647.11 KFH48159.1 - 8.8e-27 93.0 11.4 8.8e-27 93.0 11.4 6.9 3 2 2 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KFH48159.1 - 7.6e-09 35.3 8.6 1.3e-08 34.6 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFH48159.1 - 4.7e-08 32.8 7.2 8e-08 32.0 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFH48159.1 - 5.2e-08 32.6 11.7 9.5e-08 31.8 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH48159.1 - 2.1e-07 30.6 9.6 3.7e-07 29.9 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH48159.1 - 2.7e-06 27.6 9.1 4.6e-06 26.9 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFH48159.1 - 4.6e-06 26.6 9.3 9.2e-06 25.6 9.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFH48159.1 - 4.8e-06 26.4 10.7 8.2e-06 25.7 10.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain VGPC1_C PF16799.5 KFH48159.1 - 0.0022 17.9 0.6 0.0022 17.9 0.6 3.8 3 0 0 3 3 3 1 C-terminal membrane-localisation domain of ion-channel, VCN1 JIP_LZII PF16471.5 KFH48159.1 - 0.0032 17.6 2.9 0.0032 17.6 2.9 7.1 4 2 1 6 6 6 2 JNK-interacting protein leucine zipper II zf-C3HC4_4 PF15227.6 KFH48159.1 - 0.0057 16.8 7.1 0.011 15.8 7.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DivIC PF04977.15 KFH48159.1 - 0.014 15.2 2.8 0.014 15.2 2.8 9.5 4 2 4 9 9 9 0 Septum formation initiator zf-rbx1 PF12678.7 KFH48159.1 - 0.025 14.9 8.1 0.12 12.6 8.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C2HC_2 PF13913.6 KFH48159.1 - 0.033 14.1 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-RING_6 PF14835.6 KFH48159.1 - 0.092 12.6 2.1 0.19 11.6 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TSC22 PF01166.18 KFH48159.1 - 0.11 12.9 26.6 1.5 9.2 0.8 7.2 5 1 3 8 8 7 0 TSC-22/dip/bun family zf-RING_4 PF14570.6 KFH48159.1 - 0.25 11.2 7.2 1.1 9.1 7.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFH48159.1 - 0.27 11.1 5.2 0.56 10.1 5.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2935 PF11155.8 KFH48159.1 - 0.43 10.9 11.7 36 4.7 1.7 4.7 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) zf-UDP PF14569.6 KFH48159.1 - 0.54 10.4 3.8 1.5 8.9 3.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2H2_jaz PF12171.8 KFH48159.1 - 1.4 9.2 4.9 28 5.2 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 KFH48159.1 - 1.7 8.8 11.2 14 5.9 11.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 KFH48159.1 - 3.3 7.6 5.1 8.2 6.3 5.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger Baculo_PEP_C PF04513.12 KFH48159.1 - 5.6 7.0 33.7 3.4 7.7 4.9 5.0 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KFH48159.1 - 7.4 6.9 23.5 3.9 7.8 1.3 5.5 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) RNA_pol_A_bac PF01000.26 KFH48160.1 - 1.5e-25 89.7 0.0 2.9e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFH48160.1 - 1.5e-20 72.4 0.0 2.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C1_2 PF03107.16 KFH48161.1 - 0.054 13.8 6.1 0.099 13.0 6.1 1.4 1 0 0 1 1 1 0 C1 domain EXS PF03124.14 KFH48162.1 - 1e-112 376.7 9.7 1.2e-112 376.6 9.7 1.0 1 0 0 1 1 1 1 EXS family LapA_dom PF06305.11 KFH48162.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Complex1_LYR_2 PF13233.6 KFH48163.1 - 1.4e-06 29.0 0.1 1.9e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFH48163.1 - 0.00011 22.2 0.2 0.00027 20.9 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Telomere_reg-2 PF10193.9 KFH48164.1 - 8.7e-35 119.5 0.0 3.2e-34 117.6 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein Proteasome PF00227.26 KFH48166.1 - 6.6e-47 159.5 0.0 8.3e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFH48166.1 - 1.3e-13 50.1 0.2 1.3e-13 50.1 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Pkinase PF00069.25 KFH48167.1 - 2.6e-53 181.1 0.0 3.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48167.1 - 7.8e-42 143.3 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFH48167.1 - 0.0013 17.7 0.2 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KFH48167.1 - 0.0065 15.8 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFH48167.1 - 0.0072 16.3 0.7 0.34 10.8 0.1 3.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH48167.1 - 0.0091 14.8 0.0 0.035 12.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFH48167.1 - 0.18 11.2 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glucosamine_iso PF01182.20 KFH48168.1 - 2.9e-69 233.4 0.0 3.6e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peroxin-3 PF04882.12 KFH48169.1 - 3.5e-175 583.5 0.8 4.1e-175 583.3 0.8 1.0 1 0 0 1 1 1 1 Peroxin-3 PI-PLC-X PF00388.19 KFH48170.1 - 4.3e-10 39.4 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain GFO_IDH_MocA PF01408.22 KFH48172.1 - 9e-10 39.4 0.0 2.2e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFH48172.1 - 1.4e-05 25.0 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PUF PF00806.19 KFH48173.1 - 3e-19 67.6 0.1 0.00079 19.0 0.0 6.3 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KFH48173.1 - 2.5e-14 52.8 0.0 5.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFH48173.1 - 0.0099 15.7 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif COPIIcoated_ERV PF07970.12 KFH48175.1 - 9.2e-89 297.0 0.0 2.1e-88 295.9 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFH48175.1 - 2.8e-31 107.7 0.2 1.3e-30 105.6 0.0 2.2 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NUDIX PF00293.28 KFH48176.1 - 0.0062 16.6 0.2 0.02 15.0 0.1 2.0 2 0 0 2 2 2 1 NUDIX domain dCMP_cyt_deam_1 PF00383.23 KFH48177.1 - 2.7e-14 52.9 0.0 4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KFH48177.1 - 7.1e-09 36.0 2.6 4.3e-08 33.4 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KFH48177.1 - 0.00035 20.2 0.6 0.16 11.5 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Dicty_REP PF05086.12 KFH48178.1 - 8.9 4.1 19.1 0.16 9.9 11.4 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Acyl-CoA_dh_N PF02771.16 KFH48179.1 - 6.8e-25 87.9 0.3 1.3e-24 87.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFH48179.1 - 2.7e-24 86.1 0.2 4.7e-24 85.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFH48179.1 - 3.4e-17 62.4 0.0 7.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFH48179.1 - 1.6e-05 25.2 0.1 2.9e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1524 PF07510.11 KFH48180.1 - 9e-09 35.3 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Drc1-Sld2 PF11719.8 KFH48181.1 - 3.3e-103 346.7 22.4 3.8e-103 346.5 22.4 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DUF569 PF04601.13 KFH48181.1 - 0.019 14.7 0.1 0.048 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF569) M_domain PF12938.7 KFH48181.1 - 0.61 9.8 5.7 1.3 8.8 5.7 1.5 1 0 0 1 1 1 0 M domain of GW182 FGE-sulfatase PF03781.16 KFH48182.1 - 7.1e-43 147.1 4.8 9.7e-43 146.6 4.8 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 COX6B PF02297.17 KFH48183.1 - 3.5e-20 72.0 4.4 4.5e-20 71.7 4.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ATP_bind_3 PF01171.20 KFH48184.1 - 6.1e-43 146.7 0.0 6.6e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family APG5 PF04106.12 KFH48184.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg5 tRNA_Me_trans PF03054.16 KFH48184.1 - 0.12 11.1 0.0 0.37 9.5 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase Asp PF00026.23 KFH48185.1 - 6.2e-109 364.2 0.0 7.4e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH48185.1 - 1.4e-15 58.0 1.4 5.3e-13 49.6 1.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFH48185.1 - 4e-05 23.5 0.0 0.00082 19.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFH48185.1 - 6e-05 23.6 0.1 0.71 10.6 0.0 3.0 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KFH48185.1 - 0.0016 18.9 0.0 2.4 8.8 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease tRNA-synt_2b PF00587.25 KFH48186.1 - 5.3e-21 75.4 0.0 7.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFH48186.1 - 2.5e-08 34.1 0.8 4.2e-08 33.4 0.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HlyD_D4 PF16572.5 KFH48186.1 - 2.8 7.9 7.7 0.62 10.0 1.2 2.8 3 0 0 3 3 3 0 Long alpha hairpin domain of cation efflux system protein, CusB CFIA_Pcf11 PF11526.8 KFH48188.1 - 0.0001 22.7 3.3 0.00045 20.7 3.2 2.0 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 KFH48188.1 - 0.00014 21.7 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.13 KFH48188.1 - 0.00044 21.0 0.0 0.0017 19.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.6 KFH48188.1 - 0.13 13.2 1.7 6.9 7.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFH48188.1 - 0.71 9.5 6.5 0.74 9.5 2.9 2.6 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 KFH48188.1 - 1.5 8.6 3.8 0.83 9.4 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF3337 PF11816.8 KFH48189.1 - 1.5e-53 181.2 0.0 1.5e-53 181.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFH48189.1 - 2.6e-16 59.7 9.8 0.0003 21.5 0.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KFH48189.1 - 0.00017 20.4 0.1 0.0029 16.3 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFH48189.1 - 0.028 14.7 0.1 3.7 7.9 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ATG13 PF10033.9 KFH48189.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 13 ANAPC1 PF12859.7 KFH48190.1 - 3.7e-37 127.8 0.1 3.7e-37 127.8 0.1 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KFH48190.1 - 0.036 14.5 1.6 9.3 6.9 0.2 4.0 3 0 0 3 3 3 0 Proteasome/cyclosome repeat tRNA-synt_2 PF00152.20 KFH48191.1 - 1.3e-78 264.3 0.0 1.7e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFH48191.1 - 2.9e-09 36.8 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sec23_trunk PF04811.15 KFH48193.1 - 2.2e-52 178.0 0.0 5.1e-52 176.9 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFH48193.1 - 1.1e-23 83.0 0.0 2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFH48193.1 - 3.6e-17 62.9 0.0 6.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFH48193.1 - 8.9e-16 57.7 5.7 1.9e-15 56.6 5.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFH48193.1 - 2.4e-06 27.3 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Gon7 PF08738.10 KFH48194.1 - 1.9e-12 47.2 1.8 1.3e-11 44.5 0.7 2.0 1 1 1 2 2 2 2 Gon7 family GatB_N PF02934.15 KFH48195.1 - 9e-98 327.0 0.0 1.2e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KFH48195.1 - 4.5e-14 52.6 0.0 2.8e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 GatB domain WBS_methylT PF12589.8 KFH48195.1 - 0.21 12.4 3.0 1.5 9.6 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome FRQ PF09421.10 KFH48196.1 - 0 1454.2 51.2 0 1453.9 51.2 1.0 1 0 0 1 1 1 1 Frequency clock protein MscS_porin PF12795.7 KFH48196.1 - 2.4 7.7 4.6 0.48 9.9 1.1 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EBP PF05241.12 KFH48197.1 - 6.5e-57 191.8 8.5 8e-57 191.6 8.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein MoeA_N PF03453.17 KFH48198.1 - 0.017 14.9 3.8 0.034 13.9 3.8 1.7 1 1 0 1 1 1 0 MoeA N-terminal region (domain I and II) UQ_con PF00179.26 KFH48199.1 - 2.6e-50 169.7 0.0 2.9e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFH48199.1 - 0.0039 16.9 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFH48199.1 - 0.033 14.5 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KFH48199.1 - 0.037 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF917 PF06032.12 KFH48200.1 - 1.7e-126 421.8 0.6 2.6e-126 421.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KFH48200.1 - 3.7e-29 101.9 0.3 2.3e-26 92.7 0.0 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFH48200.1 - 5.5e-27 94.6 0.1 2.2e-24 86.1 0.0 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 KFH48200.1 - 3.1e-05 23.6 0.3 0.00021 20.9 0.1 2.4 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KFH48200.1 - 0.00021 20.1 0.3 0.0056 15.3 0.0 2.4 2 0 0 2 2 2 1 MutL protein DDR PF08841.10 KFH48200.1 - 0.032 13.2 0.8 6 5.8 0.0 2.7 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 KFH48200.1 - 0.041 13.1 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 StbA protein FtsA PF14450.6 KFH48200.1 - 0.054 13.9 0.9 26 5.3 0.0 3.5 3 0 0 3 3 3 0 Cell division protein FtsA RAP1 PF07218.11 KFH48202.1 - 0.4 8.9 1.5 0.37 9.0 1.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LIM_bind PF01803.16 KFH48203.1 - 1.9e-75 253.5 0.0 1.9e-75 253.5 0.0 4.1 3 1 0 3 3 3 1 LIM-domain binding protein SPX PF03105.19 KFH48204.1 - 1.9e-37 130.1 0.0 6.6e-24 85.5 0.0 2.5 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 KFH48204.1 - 3.7e-32 112.0 34.8 2.3e-31 109.4 34.8 1.9 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFH48204.1 - 1.6e-26 93.3 33.1 1.6e-26 93.3 33.1 1.8 2 1 0 2 2 2 1 Citrate transporter Rcd1 PF04078.13 KFH48204.1 - 0.13 11.5 1.4 0.56 9.4 0.3 2.1 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like SMN PF06003.12 KFH48205.1 - 2e-08 33.9 8.1 1.1e-06 28.2 1.5 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) MSA-2c PF12238.8 KFH48205.1 - 0.02 14.9 0.3 0.026 14.5 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c eIF3_N PF09440.10 KFH48206.1 - 1.7e-25 90.0 3.8 6.7e-17 62.2 2.2 3.1 3 1 1 4 4 4 2 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFH48206.1 - 2.1e-14 53.9 0.0 6.9e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain DUF771 PF05595.11 KFH48206.1 - 0.029 14.3 0.2 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF771) U3_assoc_6 PF08640.11 KFH48207.1 - 4.8e-28 97.0 1.2 3.2e-26 91.2 0.5 3.1 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KFH48207.1 - 5.7e-05 22.4 0.7 0.0001 21.6 0.6 1.5 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFH48207.1 - 0.00064 20.3 0.0 0.62 11.0 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFH48207.1 - 0.12 12.5 1.3 22 5.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FHA PF00498.26 KFH48208.1 - 1.4e-13 50.9 0.0 2.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Hydrolase PF00702.26 KFH48208.1 - 0.021 15.1 0.0 0.25 11.6 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH48208.1 - 0.042 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Presenilin PF01080.17 KFH48208.1 - 1.5 7.5 5.8 2 7.1 5.8 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KFH48209.1 - 9.1e-22 77.5 85.1 1.2e-17 63.9 55.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH48209.1 - 2.6e-05 22.9 25.8 4.2e-05 22.2 25.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAM165 PF14981.6 KFH48209.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.5 3 0 0 3 3 3 0 FAM165 family DNA_pol_A_exo1 PF01612.20 KFH48210.1 - 1.6e-40 138.7 0.0 2.4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFH48210.1 - 7.2e-28 97.1 1.3 2.4e-27 95.5 1.3 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFH48210.1 - 1.3e-11 44.3 0.0 2.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain RR_TM4-6 PF06459.12 KFH48210.1 - 9.7 5.9 16.2 16 5.2 16.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GRAB PF10375.9 KFH48211.1 - 3.3e-09 36.3 0.1 7.1e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KFH48211.1 - 4.1e-05 22.6 24.0 4.1e-05 22.6 24.0 2.9 2 1 1 3 3 2 1 Spc7 kinetochore protein Rootletin PF15035.6 KFH48211.1 - 0.012 15.6 19.1 0.012 15.6 19.1 3.6 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Dak2 PF02734.17 KFH48211.1 - 0.11 12.4 4.2 0.42 10.5 4.2 2.1 1 0 0 1 1 1 0 DAK2 domain DUF1664 PF07889.12 KFH48211.1 - 0.12 12.4 28.8 0.15 12.1 1.0 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) HicB_lk_antitox PF15919.5 KFH48211.1 - 0.47 10.6 4.1 2.1 8.5 0.6 2.9 2 1 1 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system Baculo_PEP_C PF04513.12 KFH48211.1 - 0.71 9.9 18.4 0.31 11.1 2.4 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KFH48211.1 - 0.86 9.6 31.8 0.96 9.5 6.4 4.3 1 1 2 4 4 4 0 Laminin Domain II Golgin_A5 PF09787.9 KFH48211.1 - 0.91 8.9 61.1 0.36 10.3 22.8 3.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 Filament PF00038.21 KFH48211.1 - 0.98 8.9 55.6 1.9 8.0 31.0 2.4 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 KFH48211.1 - 1.8 8.7 30.6 5 7.3 8.4 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3967 PF13152.6 KFH48211.1 - 1.9 8.3 8.2 2.2 8.1 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) KASH_CCD PF14662.6 KFH48211.1 - 2.7 7.8 55.8 1.2 9.0 10.9 3.5 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF745 PF05335.13 KFH48211.1 - 3.3 7.4 45.9 0.11 12.2 12.3 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 KFH48211.1 - 3.6 8.1 18.1 0.72 10.4 3.5 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 KFH48211.1 - 3.9 7.8 36.4 0.67 10.3 3.3 4.2 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Tup_N PF08581.10 KFH48211.1 - 4.6 7.6 32.0 0.06 13.6 3.1 4.9 2 1 2 4 4 4 0 Tup N-terminal CHD5 PF04420.14 KFH48212.1 - 4.7e-56 189.0 0.5 1.1e-55 187.8 0.5 1.6 1 1 0 1 1 1 1 CHD5-like protein KH_1 PF00013.29 KFH48213.1 - 3.1e-49 164.6 14.6 1.8e-17 62.9 1.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFH48213.1 - 1.7e-12 47.0 1.7 0.012 15.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFH48213.1 - 2.3e-08 33.8 5.5 0.18 11.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFH48213.1 - 0.00024 21.1 2.8 1.7 8.8 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KFH48213.1 - 0.00051 20.0 0.0 0.22 11.6 0.0 3.0 3 0 0 3 3 3 1 KH-like RNA-binding domain Sugar_tr PF00083.24 KFH48214.1 - 9.6e-93 311.5 24.4 1.2e-92 311.2 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH48214.1 - 4.1e-16 58.9 45.9 6e-11 41.9 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.9 KFH48215.1 - 2.6e-38 131.8 9.0 2.6e-38 131.8 9.0 2.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KFH48215.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Img2 PF05046.14 KFH48216.1 - 1.7e-20 73.1 0.0 2.2e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF4050 PF13259.6 KFH48219.1 - 1.4e-52 178.7 0.9 3.3e-52 177.5 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Macoilin PF09726.9 KFH48219.1 - 0.17 10.4 0.4 0.19 10.3 0.4 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KFH48219.1 - 0.18 10.0 3.5 0.25 9.6 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PHF12_MRG_bd PF16737.5 KFH48220.1 - 0.026 14.2 0.7 0.28 10.9 0.4 2.3 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain NAD_binding_6 PF08030.12 KFH48223.1 - 4.7e-31 108.0 0.0 7.7e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH48223.1 - 2.6e-21 75.8 0.6 1.6e-20 73.2 0.0 2.5 3 0 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.19 KFH48223.1 - 3.6e-19 69.1 10.7 3.6e-19 69.1 10.7 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KFH48223.1 - 0.079 13.6 0.0 0.33 11.6 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Mis14 PF08641.12 KFH48225.1 - 2e-18 67.0 0.9 4.8e-18 65.8 0.1 1.9 2 0 0 2 2 2 1 Kinetochore protein Mis14 like VitK2_biosynth PF02621.14 KFH48225.1 - 0.013 15.1 0.8 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Menaquinone biosynthesis Rpn3_C PF08375.11 KFH48226.1 - 8.2e-27 93.4 1.6 2.9e-26 91.7 1.6 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KFH48226.1 - 5.3e-21 75.1 0.3 5.8e-20 71.8 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KFH48226.1 - 0.0063 16.5 0.1 0.022 14.8 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat FMO-like PF00743.19 KFH48227.1 - 3e-30 105.1 0.0 2.9e-24 85.4 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFH48227.1 - 6.4e-14 51.9 0.0 4.6e-11 42.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFH48227.1 - 6.4e-10 38.7 0.0 1.9e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFH48227.1 - 6.2e-09 35.5 0.0 2.1e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH48227.1 - 5.8e-06 26.4 0.1 0.0015 18.6 0.1 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFH48227.1 - 0.007 15.6 0.3 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH48227.1 - 0.045 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH48227.1 - 0.15 11.6 2.2 0.62 9.6 0.1 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 KFH48228.1 - 1.2e-36 126.0 0.0 2e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH48228.1 - 1e-27 97.2 0.0 1.8e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH48228.1 - 5.3e-06 26.5 0.1 2.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFH48228.1 - 0.0023 17.5 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KFH48228.1 - 0.034 14.8 0.0 0.091 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KFH48229.1 - 5.7e-38 130.7 43.6 5.7e-38 130.7 43.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48229.1 - 6.1e-10 38.6 10.7 6.1e-10 38.6 10.7 2.1 3 1 0 3 3 3 1 Sugar (and other) transporter Sporozoite_P67 PF05642.11 KFH48230.1 - 0.24 9.4 7.7 0.4 8.7 7.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.11 KFH48230.1 - 2.5 7.6 15.6 0.046 13.3 6.8 2.0 2 0 0 2 2 2 0 PPP4R2 Astro_capsid_p PF12226.8 KFH48230.1 - 4.2 6.4 10.2 8.6 5.4 10.2 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Herpes_pp85 PF04637.12 KFH48230.1 - 7.2 4.9 8.3 3.6 5.9 6.0 1.6 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Glyco_hydro_16 PF00722.21 KFH48231.1 - 1.3e-11 44.3 0.1 1.7e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Asp PF00026.23 KFH48232.1 - 1.6e-62 211.7 1.0 2e-62 211.4 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFH48232.1 - 1e-10 42.2 1.1 1.3e-08 35.3 0.4 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFH48232.1 - 0.0062 17.2 0.0 0.17 12.5 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KFH48232.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KFH48232.1 - 0.12 13.0 0.0 0.8 10.3 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Pneumo_att_G PF05539.11 KFH48232.1 - 4.2 6.9 6.8 7.9 6.0 6.8 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Fungal_trans_2 PF11951.8 KFH48233.1 - 1.9e-33 115.8 2.9 1.8e-21 76.4 1.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48233.1 - 1.2e-08 34.9 12.0 2.3e-08 34.0 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KFH48233.1 - 0.064 13.2 4.7 0.24 11.4 4.7 2.1 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.16 KFH48235.1 - 1.6e-31 109.5 69.1 5.1e-28 98.0 32.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH48235.1 - 0.0011 17.9 6.3 0.017 14.0 0.3 2.5 2 1 0 2 2 2 2 MFS_1 like family TrpP PF17099.5 KFH48235.1 - 0.038 13.8 1.8 0.099 12.4 1.8 1.7 1 0 0 1 1 1 0 Tryptophan transporter TrpP DNA_methylase PF00145.17 KFH48237.1 - 6.4e-33 114.5 0.0 1.9e-32 113.0 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KFH48237.1 - 2.4e-05 24.2 0.2 0.1 12.4 0.0 2.7 3 0 0 3 3 3 2 BAH domain Fungal_trans PF04082.18 KFH48238.1 - 0.00018 20.6 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TEP1_N PF05386.11 KFH48238.1 - 0.39 10.4 1.8 2.9 7.6 0.4 2.5 2 0 0 2 2 2 0 TEP1 N-terminal domain AIP3 PF03915.13 KFH48239.1 - 3.3e-155 517.2 7.0 5e-155 516.6 7.0 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 RasGAP_C PF03836.15 KFH48239.1 - 0.027 14.6 4.4 0.28 11.3 0.1 4.0 3 1 0 4 4 4 0 RasGAP C-terminus DUF1664 PF07889.12 KFH48239.1 - 0.039 14.0 6.7 3.6 7.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Med11 PF10280.9 KFH48239.1 - 0.055 13.9 0.5 1.7 9.1 0.0 2.9 2 0 0 2 2 2 0 Mediator complex protein FliL PF03748.14 KFH48239.1 - 0.09 13.4 2.4 0.58 10.8 0.0 3.3 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL NPV_P10 PF05531.12 KFH48239.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 KFH48239.1 - 0.27 11.6 7.3 13 6.3 0.0 4.4 4 0 0 4 4 4 0 Syntaxin-like protein Fib_alpha PF08702.10 KFH48239.1 - 0.87 9.8 7.5 27 5.0 0.0 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KFH48239.1 - 1.2 8.9 6.3 0.18 11.5 0.2 2.8 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Glyco_hydro_61 PF03443.14 KFH48240.1 - 4.8e-53 180.2 0.0 5.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ATP-synt_C PF00137.21 KFH48241.1 - 2.6e-11 43.7 13.0 5e-11 42.8 13.0 1.5 1 0 0 1 1 1 1 ATP synthase subunit C adh_short PF00106.25 KFH48242.1 - 4.2e-22 78.6 0.0 7.8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH48242.1 - 1.1e-19 70.9 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH48242.1 - 3.9e-05 23.6 0.0 7.1e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Pkinase PF00069.25 KFH48245.1 - 1.3e-38 132.9 0.0 1.8e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48245.1 - 3.1e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFH48245.1 - 1.8e-06 28.2 0.1 3.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFH48245.1 - 0.0032 17.7 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KFH48245.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peptidase_M43 PF05572.13 KFH48246.1 - 2.2e-12 47.1 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KFH48246.1 - 0.00093 19.4 0.0 0.0024 18.1 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KFH48246.1 - 0.0011 18.8 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 KFH48246.1 - 0.0042 16.8 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFH48246.1 - 0.037 13.3 0.7 0.056 12.6 0.7 1.2 1 0 0 1 1 1 0 Met-zincin EF-hand_8 PF13833.6 KFH48246.1 - 0.051 13.4 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Reprolysin_3 PF13582.6 KFH48246.1 - 0.084 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Prenylcys_lyase PF07156.14 KFH48247.1 - 1.6e-89 300.6 0.0 2e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KFH48247.1 - 1.6e-12 47.4 0.0 3.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFH48247.1 - 7.9e-10 38.6 0.0 2e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFH48247.1 - 3.6e-06 26.8 1.0 1.3e-05 24.9 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFH48247.1 - 7.9e-05 22.7 0.2 0.00079 19.4 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFH48247.1 - 0.0011 18.3 0.0 0.0028 16.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFH48247.1 - 0.0087 15.3 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KFH48247.1 - 0.042 12.9 0.5 0.079 12.0 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KFH48247.1 - 0.06 13.9 0.2 0.73 10.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH48247.1 - 0.061 12.6 0.5 0.6 9.3 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH48247.1 - 0.1 11.3 0.2 0.15 10.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KFH48247.1 - 0.14 11.2 0.6 0.21 10.6 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF883 PF05957.13 KFH48248.1 - 0.0036 17.9 9.2 0.063 13.9 0.6 2.8 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KFH48248.1 - 0.018 14.9 4.1 0.079 12.8 4.1 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CsbD PF05532.12 KFH48248.1 - 0.05 13.5 36.7 17 5.4 12.8 5.0 1 1 3 4 4 4 0 CsbD-like YtxH PF12732.7 KFH48248.1 - 3.3 8.3 17.3 22 5.7 7.6 3.0 1 1 1 2 2 2 0 YtxH-like protein DivIVA PF05103.13 KFH48248.1 - 7 6.7 11.4 9.9 6.3 4.7 2.3 1 1 1 2 2 2 0 DivIVA protein zf-C2H2 PF00096.26 KFH48250.1 - 2.1e-05 24.7 12.2 0.0074 16.7 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH48250.1 - 0.00031 21.0 3.8 0.00031 21.0 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH48250.1 - 0.0014 19.3 12.0 0.084 13.8 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KFH48250.1 - 0.25 10.6 0.5 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KFH48250.1 - 9.3 6.1 7.7 6.2 6.7 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DSBA PF01323.20 KFH48251.1 - 1.5e-37 129.3 0.0 1.7e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KFH48251.1 - 0.0013 18.7 0.0 0.052 13.6 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_5 PF13743.6 KFH48251.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KFH48251.1 - 0.0054 16.9 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF1525 PF07511.11 KFH48251.1 - 0.0092 16.1 0.2 0.025 14.7 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1525) Thioredoxin_2 PF13098.6 KFH48251.1 - 0.021 15.3 0.1 1.4 9.4 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain DUF3984 PF13136.6 KFH48252.1 - 9.2e-60 202.8 19.9 9.2e-60 202.8 19.9 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3984) Cwf_Cwc_15 PF04889.12 KFH48252.1 - 0.95 9.1 12.9 2.9 7.5 12.9 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2263 PF10021.9 KFH48253.1 - 1.6e-07 31.8 0.0 2.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Med9 PF07544.13 KFH48254.1 - 1.9e-15 56.7 1.2 3e-15 56.1 1.2 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DHR10 PF18595.1 KFH48254.1 - 0.0062 16.6 2.8 0.0062 16.6 2.8 1.4 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 KFH48254.1 - 0.032 14.0 0.1 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 MetOD2 PF18548.1 KFH48254.1 - 0.058 13.5 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Metanogen output domain 2 DUF4140 PF13600.6 KFH48254.1 - 0.076 13.5 3.5 0.42 11.1 3.5 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc29 PF17082.5 KFH48254.1 - 0.077 12.8 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Med21 PF11221.8 KFH48254.1 - 0.4 10.9 3.0 1.9 8.8 3.0 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Myb_DNA-bind_6 PF13921.6 KFH48256.1 - 1.9e-17 63.2 2.3 4.3e-10 39.7 0.2 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFH48256.1 - 1.6e-16 60.2 8.0 4.9e-09 36.3 0.0 4.0 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFH48256.1 - 0.0041 17.5 2.8 0.017 15.5 2.8 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KFH48256.1 - 0.2 11.9 0.2 16 5.8 0.6 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF2293 PF10056.9 KFH48256.1 - 0.33 11.2 3.1 3.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) SYS1 PF09801.9 KFH48257.1 - 1.5e-47 161.4 3.0 1.7e-47 161.2 3.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Phage_holin_5_1 PF06946.11 KFH48257.1 - 0.57 10.6 3.2 1.3 9.5 3.2 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Folliculin PF11704.8 KFH48258.1 - 1.4e-59 201.1 0.0 3.4e-59 199.9 0.0 1.6 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport zf-C2H2_3 PF13878.6 KFH48259.1 - 3.6e-06 26.7 0.0 9.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO CDC45 PF02724.14 KFH48259.1 - 1.7 6.9 6.5 2.2 6.4 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 KFH48262.1 - 8.5e-12 44.6 0.0 2.4e-10 39.8 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 KFH48263.1 - 5.4e-33 114.8 0.0 8.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KFH48263.1 - 2.4e-05 24.9 0.0 0.029 15.0 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFH48263.1 - 0.0058 16.4 0.0 1.9 8.3 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KFH48263.1 - 0.052 14.1 0.0 3 8.5 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1744 PF08490.12 KFH48264.1 - 5.2e-149 496.2 0.0 7.3e-149 495.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFH48264.1 - 1.5e-75 254.4 0.1 2.3e-75 253.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFH48264.1 - 1.9e-15 56.5 0.0 8e-13 47.9 0.0 2.7 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFH48264.1 - 5.6e-09 36.0 0.2 1.7e-08 34.4 0.2 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFH48264.1 - 1e-05 25.6 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol3_alpha PF07733.12 KFH48264.1 - 0.0082 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain MFS_1 PF07690.16 KFH48265.1 - 1.6e-33 116.1 27.4 1.6e-33 116.1 24.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KFH48265.1 - 0.00081 19.1 0.7 0.00081 19.1 0.7 2.2 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like Cupin_1 PF00190.22 KFH48267.1 - 7.6e-16 58.1 0.3 1.3e-15 57.3 0.3 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFH48267.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Glyco_hydro_47 PF01532.20 KFH48268.1 - 4.7e-176 586.2 0.0 6.4e-176 585.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 KFH48269.1 - 2.5e-45 154.2 0.7 6.6e-45 152.8 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFH48269.1 - 9.9e-10 38.2 0.1 6.4e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFH48269.1 - 8e-09 35.6 0.3 3.1e-08 33.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH48269.1 - 6.3e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFH48269.1 - 2.9e-07 31.0 0.5 3.2e-05 24.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFH48269.1 - 4.9e-06 25.9 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFH48269.1 - 4.9e-05 23.6 1.4 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFH48269.1 - 0.00026 20.8 0.0 0.00076 19.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFH48269.1 - 0.00037 20.2 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 KFH48269.1 - 0.00039 20.4 0.0 0.031 14.3 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFH48269.1 - 0.00053 20.5 0.0 0.0016 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KFH48269.1 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KFH48269.1 - 0.00099 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFH48269.1 - 0.0016 18.0 0.1 0.0096 15.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KFH48269.1 - 0.0018 18.3 0.1 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFH48269.1 - 0.002 17.4 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KFH48269.1 - 0.0023 17.9 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 NTPase DegS PF05384.11 KFH48269.1 - 0.0027 17.2 0.5 0.0055 16.2 0.5 1.4 1 0 0 1 1 1 1 Sensor protein DegS AAA_30 PF13604.6 KFH48269.1 - 0.0047 16.7 0.1 0.012 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KFH48269.1 - 0.0059 16.5 0.2 0.11 12.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_3 PF07726.11 KFH48269.1 - 0.0061 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFH48269.1 - 0.0071 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFH48269.1 - 0.0082 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFH48269.1 - 0.0096 15.3 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KFH48269.1 - 0.011 15.5 0.1 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KFH48269.1 - 0.018 14.8 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFH48269.1 - 0.03 13.7 0.9 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KFH48269.1 - 0.033 14.1 0.6 0.24 11.3 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KFH48269.1 - 0.039 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KFH48269.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KFH48269.1 - 0.076 12.7 0.1 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFH48269.1 - 0.11 12.0 1.4 0.27 10.8 0.1 2.1 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KFH48269.1 - 0.13 12.5 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFH48269.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Acetyltransf_8 PF13523.6 KFH48271.1 - 2.3e-47 160.3 1.1 3.3e-47 159.8 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CRAL_TRIO PF00650.20 KFH48272.1 - 3.2e-35 121.2 0.0 5.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFH48272.1 - 3.6e-07 30.3 0.1 1e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFH48272.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Herpes_U59 PF04529.12 KFH48272.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein DUF1769 PF08588.10 KFH48272.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Peroxidase_2 PF01328.17 KFH48274.1 - 3.8e-57 193.8 0.0 4.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Mito_carr PF00153.27 KFH48275.1 - 3.3e-67 222.5 12.0 2.4e-26 91.5 0.2 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFH48275.1 - 4.9e-17 62.1 0.7 2.6e-11 43.8 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFH48275.1 - 4.1e-16 57.3 3.8 4.5e-05 22.7 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFH48275.1 - 8e-15 53.4 2.9 3.7e-06 26.4 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFH48275.1 - 2.7e-12 45.6 4.1 0.00051 19.4 0.3 3.8 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 KFH48275.1 - 2.3e-06 27.9 0.0 7.3e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KFH48275.1 - 2.6e-06 27.2 3.0 0.00063 19.5 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair Serine_protease PF18405.1 KFH48275.1 - 0.031 13.5 4.4 2.1 7.4 0.1 3.5 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Alpha-2-MRAP_C PF06401.11 KFH48275.1 - 0.18 11.7 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain EF-hand_14 PF17959.1 KFH48275.1 - 0.29 11.5 0.6 1 9.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain XPG_I PF00867.18 KFH48276.1 - 5.2e-32 110.1 0.0 9.5e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFH48276.1 - 2.2e-31 108.3 0.0 4.7e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFH48276.1 - 6.4e-06 26.7 0.0 2.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 KFH48276.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus HHH_5 PF14520.6 KFH48276.1 - 0.016 15.8 0.0 0.043 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.7 KFH48276.1 - 0.037 14.1 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif GN3L_Grn1 PF08701.11 KFH48276.1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.4 2 1 1 3 3 3 0 GNL3L/Grn1 putative GTPase Lactamase_B_6 PF16661.5 KFH48278.1 - 1.9e-64 216.7 0.0 2.9e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFH48278.1 - 3.8e-50 170.4 0.9 7.4e-50 169.4 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFH48278.1 - 2.2e-17 63.3 0.3 1.4e-15 57.5 0.0 3.3 4 0 0 4 4 4 1 Beta-Casp domain RMMBL PF07521.12 KFH48278.1 - 4.8e-16 58.4 0.0 1.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFH48278.1 - 0.049 13.1 0.0 0.81 9.2 0.0 2.4 1 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFH48278.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Aldose_epim PF01263.20 KFH48279.1 - 5.4e-55 186.8 0.0 7.4e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase WSC PF01822.19 KFH48280.1 - 1.4e-11 44.4 6.8 2.6e-11 43.5 6.8 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KFH48280.1 - 4e-05 22.9 0.8 8.2e-05 21.9 0.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 KFH48280.1 - 0.002 18.2 0.5 0.0042 17.1 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 KFH48280.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Insulin_TMD PF17870.1 KFH48280.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5305 PF17231.2 KFH48280.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PPTA PF01239.22 KFH48280.1 - 0.22 11.3 0.5 0.53 10.1 0.5 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat PIP5K PF01504.18 KFH48281.1 - 3.6e-102 341.3 0.1 3.6e-102 341.3 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase AKAP7_NLS PF10469.9 KFH48282.1 - 2.1e-30 106.2 0.0 2.8e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 KFH48282.1 - 0.054 13.7 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 LigT like Phosphoesterase Cutinase PF01083.22 KFH48283.1 - 2.3e-44 151.5 0.0 2.7e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KFH48283.1 - 0.00047 20.1 0.0 0.00065 19.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KFH48283.1 - 0.0047 16.5 0.1 0.0065 16.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_transf_28 PF03033.20 KFH48283.1 - 0.065 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Spore_YtfJ PF09579.10 KFH48284.1 - 0.13 12.5 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Glyco_hydro_16 PF00722.21 KFH48285.1 - 4.4e-27 94.7 0.1 6.3e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UPF0203 PF05254.12 KFH48286.1 - 8.6e-27 93.2 3.8 9.9e-27 93.0 3.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KFH48286.1 - 0.00063 19.7 4.8 0.0083 16.1 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KFH48286.1 - 0.00069 19.9 1.5 0.0015 18.8 1.5 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 KFH48286.1 - 0.07 13.4 4.4 0.46 10.7 4.3 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KFH48286.1 - 0.28 12.1 3.8 0.91 10.4 1.0 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5339) NDUF_B7 PF05676.13 KFH48286.1 - 0.48 10.2 4.6 4.2 7.2 0.2 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SRR1 PF07985.12 KFH48287.1 - 9.3e-06 25.6 0.0 3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 SRR1 NeuB PF03102.14 KFH48287.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 NeuB family YebG PF07130.12 KFH48289.1 - 0.024 14.5 1.9 0.031 14.1 0.1 2.1 2 0 0 2 2 2 0 YebG protein Ank_3 PF13606.6 KFH48290.1 - 5.9e-08 32.4 0.1 1.7 9.5 0.0 7.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_2 PF12796.7 KFH48290.1 - 1.8e-07 31.7 0.2 0.32 11.6 0.0 5.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48290.1 - 2.6e-07 31.1 4.6 0.13 12.9 0.0 6.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KFH48290.1 - 3.3e-06 27.3 0.8 0.36 11.4 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KFH48290.1 - 0.00059 20.1 5.5 3.6 8.0 0.0 6.4 8 0 0 8 8 8 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KFH48290.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH48290.1 - 0.021 14.7 0.3 0.039 13.8 0.3 1.5 1 0 0 1 1 1 0 F-box domain TFIID_20kDa PF03847.13 KFH48291.1 - 4.1e-18 65.6 0.2 9.1e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A HbrB PF08539.11 KFH48292.1 - 1.4e-52 178.1 0.2 4.5e-52 176.4 0.0 2.0 2 0 0 2 2 2 1 HbrB-like Hpt PF01627.23 KFH48293.1 - 8.6e-11 42.0 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Hpt domain MgsA_C PF12002.8 KFH48294.1 - 1.1e-60 204.3 0.1 2.7e-60 203.1 0.1 1.7 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFH48294.1 - 1.1e-23 83.3 0.6 2.7e-23 82.1 0.6 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFH48294.1 - 4.6e-14 53.0 0.1 8.7e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFH48294.1 - 2.7e-09 37.0 0.0 5.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFH48294.1 - 4.2e-06 27.3 0.9 0.013 15.8 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KFH48294.1 - 8.4e-06 25.6 0.0 0.00062 19.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KFH48294.1 - 1.6e-05 24.9 0.1 0.00011 22.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFH48294.1 - 6.9e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFH48294.1 - 8e-05 22.1 0.1 0.2 11.0 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFH48294.1 - 0.00029 21.1 0.2 0.0012 19.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFH48294.1 - 0.00062 19.1 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 KFH48294.1 - 0.0013 18.6 0.0 0.22 11.3 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit DUF815 PF05673.13 KFH48294.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KFH48294.1 - 0.0051 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 KFH48294.1 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KFH48294.1 - 0.0063 16.5 0.2 0.61 10.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFH48294.1 - 0.021 15.2 0.2 0.17 12.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain SKI PF01202.22 KFH48294.1 - 0.024 14.8 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.6 KFH48294.1 - 0.04 14.2 0.8 0.12 12.6 0.8 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFH48294.1 - 0.047 14.2 0.0 0.079 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFH48294.1 - 0.054 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 KFH48294.1 - 0.063 13.0 0.2 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KFH48294.1 - 0.068 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFH48294.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFH48294.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFH48294.1 - 0.17 11.3 0.0 0.41 10.0 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein TsaE PF02367.17 KFH48294.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fungal_trans PF04082.18 KFH48295.1 - 1.3e-13 50.6 0.1 2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48295.1 - 0.00011 22.2 15.0 0.00022 21.3 15.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clathrin PF00637.20 KFH48296.1 - 7.7e-19 68.0 4.3 1.3e-17 64.0 4.7 2.6 3 1 0 3 3 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 KFH48296.1 - 0.002 18.0 0.3 0.0041 17.0 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.9 KFH48296.1 - 0.0025 18.1 2.5 0.37 11.1 1.2 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40_like PF17005.5 KFH48296.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain DNA_pol_phi PF04931.13 KFH48296.1 - 0.079 11.1 37.1 0.14 10.2 37.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Vps39_2 PF10367.9 KFH48296.1 - 0.1 13.1 0.1 0.44 11.0 0.1 2.0 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 BUD22 PF09073.10 KFH48296.1 - 0.13 11.6 28.3 0.016 14.6 19.5 2.3 2 0 0 2 2 2 0 BUD22 TPR_7 PF13176.6 KFH48296.1 - 0.18 11.9 1.2 1.2 9.3 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 KFH48296.1 - 0.44 10.3 2.2 0.89 9.4 2.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger TPR_8 PF13181.6 KFH48296.1 - 0.58 10.5 2.0 6.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 KFH48296.1 - 0.66 9.8 6.3 8.7 6.1 5.4 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein zf-RING_2 PF13639.6 KFH48296.1 - 0.9 9.9 3.2 0.8 10.1 0.5 2.1 2 0 0 2 2 2 0 Ring finger domain SAPS PF04499.15 KFH48296.1 - 5 5.8 8.9 8.9 5.0 8.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DnaJ PF00226.31 KFH48297.1 - 1.5e-06 28.2 0.1 2.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PIRT PF15099.6 KFH48298.1 - 1.3 8.6 10.1 0.041 13.5 1.2 2.7 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family DUF2613 PF11021.8 KFH48298.1 - 2.6 8.2 6.1 0.51 10.5 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) polyprenyl_synt PF00348.17 KFH48300.1 - 6.5e-75 251.5 0.0 1.3e-74 250.5 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFH48300.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 PSI_integrin PF17205.3 KFH48300.1 - 0.14 12.0 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Integrin plexin domain Ferric_reduct PF01794.19 KFH48301.1 - 1.3e-23 83.5 14.5 2.9e-23 82.3 14.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFH48301.1 - 1.3e-06 28.6 0.2 0.048 13.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFH48301.1 - 7.9e-06 25.9 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain ECH_1 PF00378.20 KFH48302.1 - 9.3e-40 136.5 0.2 4.3e-37 127.8 0.1 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH48302.1 - 3.1e-25 89.4 0.1 6.2e-22 78.5 0.1 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ABC_membrane PF00664.23 KFH48303.1 - 2.1e-92 309.7 30.6 1.2e-52 179.2 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH48303.1 - 1.8e-63 213.1 0.0 1.9e-31 109.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFH48303.1 - 4.5e-14 52.4 1.9 0.00032 20.2 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFH48303.1 - 3.5e-07 29.9 0.7 0.022 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KFH48303.1 - 7e-06 26.1 2.2 1.3 8.7 0.1 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFH48303.1 - 7.8e-06 25.7 0.8 0.0031 17.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFH48303.1 - 1e-05 26.0 2.7 0.12 12.8 0.1 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KFH48303.1 - 2e-05 25.0 0.0 2 8.8 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFH48303.1 - 2.3e-05 23.8 0.4 0.33 10.2 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 KFH48303.1 - 4.6e-05 23.7 0.1 1.2 9.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KFH48303.1 - 0.00011 22.2 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KFH48303.1 - 0.00051 20.6 0.0 1.8 9.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain APS_kinase PF01583.20 KFH48303.1 - 0.0006 19.7 0.2 0.095 12.6 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 KFH48303.1 - 0.00072 19.2 0.1 3.7 7.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF3987 PF13148.6 KFH48303.1 - 0.00084 18.4 0.1 0.56 9.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) SbcCD_C PF13558.6 KFH48303.1 - 0.00096 19.3 0.7 3.9 7.8 0.3 3.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KFH48303.1 - 0.0023 16.8 0.3 0.1 11.4 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 KFH48303.1 - 0.0033 17.6 0.1 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFH48303.1 - 0.0081 16.2 0.1 8.2 6.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KFH48303.1 - 0.01 16.0 1.3 0.65 10.1 0.1 2.6 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KFH48303.1 - 0.011 16.3 0.4 3 8.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFH48303.1 - 0.025 15.0 0.2 15 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KFH48303.1 - 0.035 13.3 0.0 7.1 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 KFH48303.1 - 0.043 13.0 0.2 8.6 5.5 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 KFH48303.1 - 0.057 13.4 0.0 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KFH48303.1 - 0.12 12.1 0.1 0.65 9.7 0.0 2.4 3 1 0 3 3 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KFH48303.1 - 0.16 12.0 0.2 15 5.7 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KFH48303.1 - 0.17 11.4 0.7 14 5.2 0.1 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region Glyco_transf_20 PF00982.21 KFH48304.1 - 5.1e-195 648.7 0.0 5.9e-195 648.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KFH48304.1 - 0.031 14.0 0.2 0.083 12.6 0.1 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain KAR9 PF08580.10 KFH48305.1 - 0.34 9.4 5.1 0.43 9.1 5.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Amidohydro_1 PF01979.20 KFH48307.1 - 1.7e-22 80.2 0.0 3.1e-14 53.0 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KFH48307.1 - 1.6e-13 51.0 0.1 1.5e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.21 KFH48308.1 - 1.3e-47 162.5 0.0 2.9e-45 154.7 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 KFH48308.1 - 0.0046 17.1 0.0 3.3 8.0 0.0 2.9 2 1 0 2 2 2 2 Death domain PglL_A PF15864.5 KFH48309.1 - 2.4 8.0 4.7 1.6 8.6 0.6 2.2 2 0 0 2 2 2 0 Protein glycosylation ligase Vps39_1 PF10366.9 KFH48310.1 - 1.1e-34 119.0 0.0 2.6e-33 114.5 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFH48310.1 - 1.4e-26 93.0 0.0 4.1e-26 91.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFH48310.1 - 2.2e-16 60.3 0.0 5.2e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFH48310.1 - 1e-05 25.4 1.2 0.00024 21.0 0.2 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_12 PF13424.6 KFH48310.1 - 0.002 18.4 0.5 3.8 7.9 0.0 4.2 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH48310.1 - 0.062 13.1 6.6 1.1 9.1 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFH48310.1 - 0.14 12.7 0.2 10 6.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48310.1 - 1 9.8 3.5 36 4.9 0.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFH48310.1 - 1.1 9.5 5.1 55 4.2 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Actin PF00022.19 KFH48311.1 - 1.4e-20 73.4 0.1 2.4e-19 69.2 0.0 2.8 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.13 KFH48311.1 - 0.17 10.7 0.0 2.2 7.0 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein UCH PF00443.29 KFH48312.1 - 8.4e-40 136.9 0.0 1.4e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFH48312.1 - 2.5e-09 37.2 0.3 1.5e-08 34.7 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KFH48312.1 - 1e-07 31.7 0.0 0.0007 19.5 0.0 3.0 2 0 0 2 2 2 2 A repeated domain in UCH-protein Fungal_trans PF04082.18 KFH48313.1 - 8.3e-07 28.3 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Caskin-Pro-rich PF16907.5 KFH48314.1 - 0.023 15.2 0.6 0.023 15.2 0.6 6.5 6 1 1 7 7 7 0 Proline rich region of Caskin proteins FAD_binding_4 PF01565.23 KFH48316.1 - 2.9e-22 78.9 1.5 5.1e-22 78.1 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFH48316.1 - 0.0015 18.6 0.1 0.0035 17.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cyclin_N PF00134.23 KFH48317.1 - 4.9e-13 48.9 2.2 5.3e-13 48.8 0.5 1.9 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFH48317.1 - 0.013 15.9 0.8 0.046 14.1 0.2 2.2 2 0 0 2 2 2 0 Cyclin C-terminal domain Turandot PF07240.11 KFH48317.1 - 0.14 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Chorion_3 PF05387.11 KFH48317.1 - 0.16 11.6 3.9 0.21 11.2 3.9 1.1 1 0 0 1 1 1 0 Chorion family 3 VSP PF03302.13 KFH48318.1 - 0.00012 21.1 2.3 0.00023 20.1 2.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein UPF0060 PF02694.15 KFH48318.1 - 0.045 14.0 0.2 0.08 13.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF4177 PF13783.6 KFH48319.1 - 0.14 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) C2 PF00168.30 KFH48320.1 - 1.1e-27 96.3 0.0 1.1e-15 57.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain PPTA PF01239.22 KFH48321.1 - 0.006 16.3 18.5 0.024 14.4 0.8 4.0 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Mito_carr PF00153.27 KFH48323.1 - 2.6e-46 155.5 8.2 3e-18 65.5 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFH48323.1 - 0.0033 16.6 1.1 0.073 12.2 0.1 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease CfAFP PF05264.11 KFH48324.1 - 2.8 7.9 8.8 10 6.1 0.3 2.1 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) GH115_C PF17829.1 KFH48325.1 - 4.9e-06 26.5 0.4 0.012 15.5 0.1 2.4 2 1 1 3 3 3 2 Gylcosyl hydrolase family 115 C-terminal domain Ank_2 PF12796.7 KFH48326.1 - 7.1e-21 74.6 0.3 1.6e-10 41.4 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48326.1 - 1.4e-15 57.4 4.0 2.6e-07 31.1 0.3 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH48326.1 - 3.8e-15 54.5 2.0 0.0014 18.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFH48326.1 - 8.4e-15 54.6 8.3 4.5e-06 26.8 0.4 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH48326.1 - 4.4e-13 49.0 8.7 0.00012 22.3 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeat zf-CCCH_6 PF18585.1 KFH48326.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Acyl-CoA_dh_1 PF00441.24 KFH48327.1 - 5.8e-43 146.7 0.2 8.2e-43 146.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFH48327.1 - 5.8e-22 78.5 0.0 1.3e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFH48327.1 - 7.8e-21 74.1 0.1 1.3e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KFH48327.1 - 5.6e-20 71.3 0.4 1e-19 70.4 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KFH48327.1 - 6.2e-09 36.2 0.0 9.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KFH48327.1 - 0.073 13.6 0.0 0.67 10.5 0.0 2.4 2 1 1 3 3 3 0 C6 domain Apidaecin PF00807.17 KFH48327.1 - 8 6.7 7.1 18 5.6 7.1 1.6 1 0 0 1 1 1 0 Apidaecin FAD_binding_3 PF01494.19 KFH48328.1 - 1.7e-29 103.1 0.4 4.3e-18 65.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFH48328.1 - 8.6e-10 38.3 0.5 0.0004 19.7 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH48328.1 - 1.6e-07 31.3 0.5 0.00066 19.4 0.2 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFH48328.1 - 1.6e-07 31.5 0.1 1.1e-05 25.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFH48328.1 - 9.2e-06 25.1 0.0 0.0024 17.2 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFH48328.1 - 1.2e-05 24.6 0.5 0.015 14.4 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KFH48328.1 - 0.00022 20.2 0.5 0.041 12.7 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KFH48328.1 - 0.00024 21.6 0.1 0.2 12.2 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFH48328.1 - 0.00028 20.3 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KFH48328.1 - 0.00057 18.7 0.0 0.026 13.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFH48328.1 - 0.0012 18.0 0.1 0.0026 16.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFH48328.1 - 0.0034 16.5 0.0 0.065 12.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 KFH48328.1 - 0.0038 17.2 0.3 0.21 11.6 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFH48328.1 - 0.17 11.1 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.6 KFH48330.1 - 4.1e-62 209.8 0.3 4.7e-62 209.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH48330.1 - 6.5e-47 159.5 0.1 8.1e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH48330.1 - 5.9e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFH48330.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFH48330.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KFH48330.1 - 0.043 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 KFH48331.1 - 3.7e-104 349.1 23.7 4.8e-104 348.7 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH48331.1 - 1.4e-24 86.7 60.2 2.1e-23 82.8 32.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KFH48331.1 - 0.52 10.9 5.0 0.8 10.3 2.6 2.6 1 1 1 2 2 2 0 Phage holin family 2 Gpi1 PF05024.15 KFH48332.1 - 8e-77 257.6 4.4 1.5e-76 256.7 4.4 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 KFH48332.1 - 0.0021 17.5 0.3 0.0041 16.5 0.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyoxalase PF00903.25 KFH48333.1 - 0.00032 20.9 0.1 0.0018 18.5 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XPG_I PF00867.18 KFH48334.1 - 6e-26 90.6 0.0 1.4e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KFH48334.1 - 1.6e-22 80.4 1.7 3.5e-22 79.3 0.5 2.3 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KFH48334.1 - 1.2e-06 28.9 0.0 2.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DUF4452 PF14618.6 KFH48336.1 - 1.2e-76 256.3 15.8 1.4e-76 256.0 15.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Retinal PF15449.6 KFH48336.1 - 0.0059 14.5 12.8 0.0089 13.9 12.8 1.2 1 0 0 1 1 1 1 Retinal protein AAA PF00004.29 KFH48338.1 - 6.6e-32 110.7 0.0 9.1e-14 52.0 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFH48338.1 - 2.6e-12 47.2 5.6 0.24 11.7 0.0 6.4 3 3 1 4 4 4 3 AAA domain AAA_5 PF07728.14 KFH48338.1 - 3.7e-11 43.2 0.8 0.018 15.0 0.0 5.1 3 3 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_6 PF17866.1 KFH48338.1 - 4e-10 39.7 3.3 5.9e-09 36.0 0.2 3.9 5 0 0 5 5 3 1 AAA lid domain AAA_16 PF13191.6 KFH48338.1 - 1.3e-08 35.4 2.4 1.5 9.1 0.0 5.5 3 2 1 5 5 5 2 AAA ATPase domain AAA_30 PF13604.6 KFH48338.1 - 1.4e-08 34.7 0.1 0.052 13.3 0.0 4.1 3 1 0 3 3 3 3 AAA domain AAA_33 PF13671.6 KFH48338.1 - 2.9e-07 30.7 0.0 0.65 10.1 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_24 PF13479.6 KFH48338.1 - 1.1e-06 28.5 0.5 0.97 9.1 0.1 3.4 3 0 0 3 3 3 3 AAA domain AAA_28 PF13521.6 KFH48338.1 - 1.9e-06 28.2 0.9 0.67 10.2 0.0 4.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KFH48338.1 - 3.4e-06 27.4 0.0 3.1 8.2 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 KFH48338.1 - 4.2e-06 27.3 0.1 2.7 8.5 0.0 4.4 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KFH48338.1 - 4.4e-06 26.5 0.2 4.4 7.0 0.0 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFH48338.1 - 1.1e-05 24.9 0.1 0.57 9.5 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFH48338.1 - 7.3e-05 22.5 0.2 0.34 10.6 0.0 4.0 4 1 0 4 4 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 KFH48338.1 - 0.00021 20.9 0.7 0.7 9.4 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_17 PF13207.6 KFH48338.1 - 0.00024 21.5 2.6 0.2 12.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 KFH48338.1 - 0.0015 18.9 4.2 4.6 7.6 0.0 4.4 4 1 1 5 5 4 0 AAA domain Torsin PF06309.11 KFH48338.1 - 0.0017 18.5 0.0 17 5.5 0.0 3.4 3 0 0 3 3 3 0 Torsin IstB_IS21 PF01695.17 KFH48338.1 - 0.0017 18.1 0.0 19 4.9 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.6 KFH48338.1 - 0.0023 17.8 1.1 0.57 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KFH48338.1 - 0.0025 18.3 0.1 3.5 8.2 0.0 3.6 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 KFH48338.1 - 0.0034 17.1 0.0 0.85 9.4 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 KFH48338.1 - 0.0037 17.2 1.6 7.5 6.4 0.0 3.4 3 0 0 3 3 3 0 NTPase Viral_helicase1 PF01443.18 KFH48338.1 - 0.0044 16.8 0.0 3.4 7.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KFH48338.1 - 0.005 16.9 0.0 7.2 6.7 0.0 3.8 3 2 0 3 3 3 0 Sigma-54 interaction domain VirE PF05272.11 KFH48338.1 - 0.0095 15.7 0.0 0.48 10.1 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E TsaE PF02367.17 KFH48338.1 - 0.013 15.5 0.1 28 4.7 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KFH48338.1 - 0.015 14.4 0.1 5.5 6.1 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 KFH48338.1 - 0.018 15.0 0.0 3.4 7.6 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase PhoH PF02562.16 KFH48338.1 - 0.022 14.2 0.1 30 4.0 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein KTI12 PF08433.10 KFH48338.1 - 0.022 14.2 0.0 25 4.2 0.0 3.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KFH48338.1 - 0.037 13.7 0.3 2.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase ResIII PF04851.15 KFH48338.1 - 0.078 13.0 2.8 31 4.5 0.0 4.6 4 2 1 5 5 5 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFH48338.1 - 0.085 12.4 1.2 38 3.8 0.0 4.1 4 0 0 4 4 4 0 AAA domain DNA_pol3_delta2 PF13177.6 KFH48338.1 - 0.12 12.1 0.0 3.4 7.4 0.0 2.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit CbiA PF01656.23 KFH48338.1 - 0.19 11.8 3.3 10 6.2 0.0 3.7 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KFH48338.1 - 0.27 10.8 6.8 0.52 9.9 0.0 3.8 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KFH48338.1 - 0.35 10.8 1.5 43 4.0 0.1 3.5 3 0 0 3 3 3 0 NACHT domain ATPase PF06745.13 KFH48338.1 - 0.75 9.1 3.1 23 4.2 0.1 3.4 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.9 KFH48338.1 - 1.2 8.3 3.2 74 2.4 0.0 4.0 4 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFH48339.1 - 3.5e-50 170.1 0.1 6.4e-24 85.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.24 KFH48339.1 - 9.7e-48 162.4 36.8 1.3e-26 93.4 11.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 KFH48339.1 - 1.7e-13 51.1 5.3 0.005 16.7 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFH48339.1 - 8.7e-09 35.1 0.8 0.001 18.6 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFH48339.1 - 3.4e-08 34.1 0.3 0.007 16.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFH48339.1 - 5.3e-08 32.5 2.9 0.0047 16.6 0.2 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFH48339.1 - 5.6e-08 33.5 0.4 0.0011 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH48339.1 - 1.3e-07 31.7 0.6 0.017 15.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFH48339.1 - 2.6e-07 31.0 0.2 0.071 13.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KFH48339.1 - 3.7e-06 26.7 0.1 0.027 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFH48339.1 - 3e-05 23.8 2.2 0.053 13.2 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KFH48339.1 - 3.6e-05 24.1 0.2 0.047 14.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFH48339.1 - 5.6e-05 23.1 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 KFH48339.1 - 6.2e-05 22.2 0.5 0.27 10.2 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KFH48339.1 - 0.00016 22.0 0.1 0.8 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFH48339.1 - 0.00028 21.1 5.8 0.15 12.3 0.4 3.4 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 KFH48339.1 - 0.00034 20.4 0.2 0.33 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 KFH48339.1 - 0.0004 20.2 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 CDR ABC transporter cobW PF02492.19 KFH48339.1 - 0.0014 18.2 2.2 0.5 9.9 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KFH48339.1 - 0.0016 18.2 0.1 3.3 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 KFH48339.1 - 0.0016 18.4 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 KFH48339.1 - 0.002 18.3 0.5 2.8 8.3 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KFH48339.1 - 0.0027 17.8 1.6 1.3 9.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFH48339.1 - 0.0053 16.6 0.6 1 9.1 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KFH48339.1 - 0.0082 15.5 4.3 0.52 9.6 1.1 2.7 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KFH48339.1 - 0.0098 16.1 0.1 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFH48339.1 - 0.013 15.5 0.9 1.8 8.5 0.1 3.5 4 0 0 4 4 4 0 NTPase AAA_18 PF13238.6 KFH48339.1 - 0.016 15.8 0.1 4.1 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 KFH48339.1 - 0.016 14.6 0.7 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KFH48339.1 - 0.018 15.0 0.7 8.5 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KFH48339.1 - 0.033 14.4 0.2 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 KFH48339.1 - 0.04 13.4 0.5 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PRK PF00485.18 KFH48339.1 - 0.052 13.3 0.3 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 KFH48339.1 - 0.058 12.7 0.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.14 KFH48339.1 - 0.082 12.8 0.7 8.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 KFH48339.1 - 0.083 12.6 0.4 6.8 6.4 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA PF00004.29 KFH48339.1 - 0.1 13.0 0.6 9.8 6.6 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFH48339.1 - 0.12 11.9 0.5 15 5.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 KFH48339.1 - 0.15 11.7 1.1 11 5.6 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KFH48339.1 - 0.15 12.5 0.1 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KFH48339.1 - 0.16 11.3 0.3 11 5.3 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRPRB PF09439.10 KFH48339.1 - 0.18 11.2 0.5 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFH48339.1 - 0.22 11.3 0.5 25 4.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 KFH48339.1 - 0.24 10.6 0.1 13 4.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 KFH48339.1 - 0.34 9.8 1.1 2 7.3 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF3087 PF11286.8 KFH48339.1 - 3.5 7.1 6.7 0.19 11.2 0.2 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF3087) Sec7 PF01369.20 KFH48340.1 - 1.5e-27 96.5 0.1 4.5e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KFH48340.1 - 1.1e-19 71.0 0.0 2.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PDGF_N PF04692.13 KFH48340.1 - 0.24 12.2 2.0 0.65 10.8 0.2 2.8 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region IKI3 PF04762.12 KFH48341.1 - 9.1e-302 1003.6 0.0 1.1e-301 1003.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KFH48341.1 - 0.00021 21.5 0.6 3 8.2 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_10 PF13374.6 KFH48341.1 - 4.4 7.3 5.4 46 4.1 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFH48341.1 - 5.8 7.3 8.6 1.2 9.5 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Gpr1_Fun34_YaaH PF01184.19 KFH48343.1 - 3.2e-53 180.4 17.7 4.6e-53 179.9 17.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1772 PF08592.11 KFH48343.1 - 10 6.5 11.1 8.3 6.7 9.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) ATPase_2 PF01637.18 KFH48344.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KFH48344.1 - 6.2e-08 33.2 0.0 1.7e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFH48344.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH48344.1 - 0.13 12.5 0.3 0.42 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain Gti1_Pac2 PF09729.9 KFH48345.1 - 1.2e-43 149.3 3.1 1e-36 126.7 0.2 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family PG_binding_2 PF08823.11 KFH48346.1 - 0.1 12.9 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain APH PF01636.23 KFH48347.1 - 4.6e-13 49.7 0.0 9.4e-12 45.4 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH48347.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AMP-binding PF00501.28 KFH48348.1 - 1.7e-73 247.6 0.0 3.4e-73 246.6 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KFH48348.1 - 2.8e-60 204.3 0.0 1.1e-35 123.2 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KFH48348.1 - 8.2e-28 96.6 0.0 3.8e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KFH48348.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RRM_1 PF00076.22 KFH48349.1 - 3.3e-14 52.5 0.0 6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFH48349.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH48349.1 - 0.029 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DMAP1_like PF17024.5 KFH48349.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative DMAP1-like RL PF17797.1 KFH48349.1 - 0.17 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 RL domain FAM60A PF15396.6 KFH48349.1 - 2.7 8.0 6.4 0.26 11.2 1.5 1.8 2 0 0 2 2 2 0 Protein Family FAM60A FMO-like PF00743.19 KFH48350.1 - 1.1e-51 175.9 0.0 2.6e-51 174.6 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFH48350.1 - 1.2e-16 60.9 0.0 3.4e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH48350.1 - 7.5e-12 45.1 0.0 8.3e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH48350.1 - 5.6e-08 32.9 0.0 1.9e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFH48350.1 - 1.8e-07 30.6 0.0 4.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KFH48350.1 - 0.00021 20.7 0.0 0.42 10.0 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFH48350.1 - 0.00026 21.5 2.7 0.061 13.9 0.3 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KFH48350.1 - 0.0004 20.6 2.0 0.00049 20.3 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 KFH48350.1 - 0.00075 18.9 0.0 1.1 8.5 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KFH48350.1 - 0.0011 19.0 0.0 0.84 9.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KFH48350.1 - 0.0022 18.2 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFH48350.1 - 0.0031 17.2 0.0 1.4 8.4 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase IlvN PF07991.12 KFH48350.1 - 0.021 14.4 0.2 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 KFH48350.1 - 0.04 13.3 0.2 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 ThiF family ELFV_dehydrog PF00208.21 KFH48350.1 - 0.071 12.8 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KFH48350.1 - 0.093 13.0 3.0 1.9 8.8 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KFH48350.1 - 0.19 10.4 0.0 11 4.6 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KFH48350.1 - 0.8 9.6 4.8 0.29 11.0 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 KFH48351.1 - 1.4e-12 48.7 4.2 1.4e-12 48.7 4.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFH48351.1 - 7.3e-12 45.5 0.6 1.4e-11 44.6 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH48351.1 - 9.2e-09 34.9 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFH48351.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 KFH48351.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KFH48351.1 - 0.9 9.6 2.6 1.4 9.0 1.6 1.7 2 0 0 2 2 2 0 Thioesterase domain DASH_Spc34 PF08657.10 KFH48352.1 - 1.3e-48 166.0 9.4 1.2e-24 87.5 6.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 SDA1 PF05285.12 KFH48352.1 - 0.006 16.0 13.6 0.0079 15.7 13.6 1.2 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 KFH48352.1 - 0.046 13.1 14.5 0.073 12.4 14.5 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KFH48352.1 - 0.059 13.1 15.4 0.093 12.5 15.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF740 PF05340.12 KFH48352.1 - 0.29 9.8 8.2 0.86 8.3 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF740) COPI_C PF06957.11 KFH48352.1 - 0.31 9.7 14.1 0.46 9.2 14.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pox_RNA_Pol_19 PF05320.12 KFH48352.1 - 0.36 10.8 7.8 0.59 10.1 7.8 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RPN2_C PF18004.1 KFH48352.1 - 0.55 10.1 9.0 1 9.3 9.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DASH_Spc19 PF08287.11 KFH48352.1 - 0.88 9.4 9.4 1.5 8.7 9.4 1.5 1 0 0 1 1 1 0 Spc19 Nop14 PF04147.12 KFH48352.1 - 1.2 7.3 19.7 1.6 6.8 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KFH48352.1 - 2.1 7.0 3.5 3.2 6.4 3.5 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 KFH48352.1 - 2.1 6.3 24.5 2.8 6.0 24.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFH48352.1 - 2.6 6.2 18.4 3.7 5.7 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 KFH48352.1 - 6.5 6.9 8.0 2.8 8.1 5.7 1.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 KFH48352.1 - 8.9 6.6 12.2 16 5.7 12.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 KFH48352.1 - 9.8 5.4 19.2 14 4.8 19.2 1.2 1 1 0 1 1 1 0 BUD22 MOZ_SAS PF01853.18 KFH48353.1 - 2.6e-55 186.9 0.0 3.9e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFH48353.1 - 1.8e-08 33.8 0.1 0.003 17.1 0.0 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KFH48353.1 - 0.0036 17.7 0.0 0.078 13.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH48353.1 - 0.026 14.7 0.0 0.074 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family VID27 PF08553.10 KFH48355.1 - 5.4e-192 637.5 0.1 6.8e-192 637.2 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KFH48355.1 - 3.9e-76 254.7 0.2 3.9e-76 254.7 0.2 2.9 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 KFH48355.1 - 2.6e-41 140.3 1.1 5.9e-41 139.2 0.5 1.9 2 0 0 2 2 2 1 VID27 PH-like domain DEAD PF00270.29 KFH48356.1 - 1.5e-43 148.6 0.0 2.2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH48356.1 - 4.7e-27 94.5 0.4 4.7e-27 94.5 0.4 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48356.1 - 0.00036 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFH48356.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.11 KFH48356.1 - 4.1 8.1 20.0 8.3 7.2 20.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family API5 PF05918.11 KFH48356.1 - 7.3 5.3 10.1 14 4.3 10.1 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TBCC PF07986.12 KFH48357.1 - 1.3e-26 92.7 0.4 1.3e-25 89.4 0.4 2.1 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFH48357.1 - 5.7e-09 36.4 0.3 1.1e-08 35.6 0.3 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Mu-like_Pro PF10123.9 KFH48357.1 - 0.1 12.1 0.5 0.16 11.5 0.5 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Cu_bind_like PF02298.17 KFH48358.1 - 0.012 15.6 0.0 0.038 14.0 0.0 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain ABC_membrane PF00664.23 KFH48359.1 - 1.1e-40 140.0 11.0 1.4e-40 139.7 11.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFH48359.1 - 8.4e-34 117.0 0.0 2.3e-33 115.6 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KFH48359.1 - 2.2e-05 24.0 0.0 0.0095 15.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFH48359.1 - 0.00012 22.5 0.1 0.00033 21.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFH48359.1 - 0.00021 21.2 0.2 0.034 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFH48359.1 - 0.0012 19.1 0.0 0.0037 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFH48359.1 - 0.0028 17.6 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFH48359.1 - 0.0072 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFH48359.1 - 0.0075 16.3 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFH48359.1 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFH48359.1 - 0.017 14.9 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFH48359.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFH48359.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH48359.1 - 0.028 13.7 0.0 0.076 12.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KFH48359.1 - 0.04 14.4 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFH48359.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KFH48359.1 - 0.047 14.1 0.0 0.24 11.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFH48359.1 - 0.049 14.2 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFH48359.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFH48359.1 - 0.069 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 KFH48359.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KFH48359.1 - 0.13 12.5 0.3 2.4 8.4 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KFH48359.1 - 0.16 11.9 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 KFH48359.1 - 0.17 11.1 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Vma12 PF11712.8 KFH48360.1 - 2.5e-46 157.2 0.0 3.7e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C3HC4_3 PF13920.6 KFH48361.1 - 0.00038 20.3 9.0 0.0006 19.6 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH48361.1 - 0.034 14.5 11.2 0.065 13.6 11.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KFH48361.1 - 0.051 13.5 7.5 0.098 12.5 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH48361.1 - 2.6 8.0 8.5 5.3 7.0 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4097 PF13349.6 KFH48362.1 - 1.8e-06 27.5 0.7 0.035 13.4 0.6 3.3 3 0 0 3 3 3 3 Putative adhesin Golgin_A5 PF09787.9 KFH48363.1 - 0.011 15.2 6.8 0.019 14.5 6.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ADIP PF11559.8 KFH48363.1 - 0.013 15.6 10.7 0.028 14.5 10.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM184 PF15665.5 KFH48363.1 - 0.017 14.9 8.2 0.031 14.1 8.2 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF3150 PF11348.8 KFH48363.1 - 0.037 13.3 0.6 0.061 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Spc7 PF08317.11 KFH48363.1 - 0.055 12.3 8.0 0.086 11.7 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1192 PF06698.11 KFH48363.1 - 0.066 13.3 0.9 0.19 11.8 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 KFH48363.1 - 0.069 13.7 11.4 0.12 12.9 11.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Lebercilin PF15619.6 KFH48363.1 - 0.074 12.7 13.6 0.73 9.5 4.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IFT57 PF10498.9 KFH48363.1 - 0.078 11.9 4.1 0.12 11.3 4.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Csm1_N PF18504.1 KFH48363.1 - 0.42 11.0 12.1 0.44 10.9 0.0 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain UPF0242 PF06785.11 KFH48363.1 - 0.69 10.0 7.9 1.2 9.2 7.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFH48363.1 - 0.86 8.9 4.2 1.5 8.1 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KFH48363.1 - 1.1 9.4 21.9 0.78 9.9 16.7 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4653 PF15546.6 KFH48363.1 - 4.5 6.8 10.4 3.5 7.2 8.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4653) ARID PF01388.21 KFH48364.1 - 3.1e-07 31.0 1.5 7.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain UDPGT PF00201.18 KFH48365.1 - 6.8e-10 38.3 0.0 1.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFH48365.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 KFH48365.1 - 0.045 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain 6PF2K PF01591.18 KFH48366.1 - 1.6e-79 266.3 0.0 2e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFH48366.1 - 1.2e-34 119.7 0.0 1.9e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFH48366.1 - 2.6e-07 30.9 0.1 6.2e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFH48366.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 F-box-like PF12937.7 KFH48367.1 - 7.9e-05 22.5 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like FOXP-CC PF16159.5 KFH48368.1 - 2.1 9.0 5.1 6.2 7.5 5.2 1.7 1 1 0 1 1 1 0 FOXP coiled-coil domain DUF829 PF05705.14 KFH48369.1 - 1.7e-42 146.0 0.0 2e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Med24_N PF11277.8 KFH48369.1 - 0.2 9.7 0.0 0.26 9.3 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF155 PF02582.14 KFH48370.1 - 1.1e-45 155.9 0.0 1.4e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1861 PF08950.10 KFH48370.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1861) DUF4051 PF13260.6 KFH48370.1 - 0.085 12.6 0.4 0.16 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Cupin_1 PF00190.22 KFH48370.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF3767 PF12597.8 KFH48371.1 - 8.2e-37 125.1 0.0 1.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CCB1 PF12046.8 KFH48371.1 - 0.065 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Linker_histone PF00538.19 KFH48373.1 - 4.7e-28 97.3 0.1 4.7e-28 97.3 0.1 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 KFH48373.1 - 1.3 8.7 17.7 1.8 8.4 17.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3140 PF11338.8 KFH48374.1 - 2.9e-35 120.5 1.0 2.9e-35 120.5 1.0 3.0 2 1 2 4 4 4 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KFH48374.1 - 3.7e-13 49.4 4.8 3.7e-13 49.4 4.8 2.6 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Cwf_Cwc_15 PF04889.12 KFH48374.1 - 0.0069 16.1 22.9 0.014 15.1 22.9 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.12 KFH48374.1 - 5.5 4.8 10.2 7.1 4.5 10.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4820 PF16091.5 KFH48374.1 - 9.7 5.5 9.5 17 4.7 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pkinase PF00069.25 KFH48375.1 - 2.5e-74 250.0 0.0 3.5e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48375.1 - 4e-31 108.2 0.0 2e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFH48375.1 - 7.2e-07 28.8 0.1 0.93 8.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KFH48375.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFH48375.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFH48375.1 - 0.033 14.1 0.0 0.91 9.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFH48375.1 - 0.17 10.8 0.1 0.7 8.8 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain RabGAP-TBC PF00566.18 KFH48376.1 - 2.2e-48 164.8 0.0 3.9e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HOOK PF05622.12 KFH48376.1 - 0.045 11.9 2.2 0.088 10.9 2.2 1.3 1 0 0 1 1 1 0 HOOK protein TRI12 PF06609.13 KFH48377.1 - 2.6e-25 88.9 16.6 3.4e-25 88.5 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH48377.1 - 9e-23 80.8 43.1 1.3e-22 80.2 40.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily BacA PF02673.18 KFH48377.1 - 0.0021 17.9 9.7 0.055 13.2 0.7 3.5 2 1 1 3 3 3 1 Bacitracin resistance protein BacA DUF3040 PF11239.8 KFH48377.1 - 0.077 13.3 0.0 0.077 13.3 0.0 5.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3040) Pox_A14 PF05767.12 KFH48377.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Saf_2TM PF18303.1 KFH48377.1 - 6.8 6.3 7.2 21 4.7 0.0 3.9 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain DUF2157 PF09925.9 KFH48377.1 - 9 6.1 18.7 2.6 7.9 0.9 4.0 1 1 1 3 3 3 0 Predicted membrane protein (DUF2157) TauD PF02668.16 KFH48378.1 - 2.8e-55 188.0 0.7 3.2e-55 187.8 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_3 PF00933.21 KFH48379.1 - 8.6e-45 153.5 0.0 1.3e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Asp_protease_2 PF13650.6 KFH48380.1 - 9.2e-13 48.7 0.0 3.6e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KFH48380.1 - 1.1e-09 38.7 0.0 1.7e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Hexapep PF00132.24 KFH48384.1 - 1.1e-06 28.1 4.5 0.0019 17.9 0.3 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFH48384.1 - 9.5e-05 20.7 0.9 0.00014 20.2 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KFH48384.1 - 0.0001 22.7 0.0 0.00081 19.8 0.0 2.3 2 1 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KFH48384.1 - 0.00017 20.6 1.7 0.0004 19.4 1.7 1.5 1 1 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KFH48384.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 KFH48384.1 - 0.069 12.9 6.6 2.9 7.7 0.2 3.5 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Abhydrolase_3 PF07859.13 KFH48385.1 - 2.1e-62 210.7 0.0 2.9e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFH48385.1 - 1.4e-06 27.5 0.0 2.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFH48385.1 - 9.8e-06 25.2 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KFH48385.1 - 0.055 12.3 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase R3H PF01424.22 KFH48387.1 - 5.2e-12 45.6 0.6 9.3e-12 44.8 0.6 1.4 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KFH48387.1 - 9.1e-05 22.2 0.0 0.00022 21.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SQS_PSY PF00494.19 KFH48388.1 - 9.8e-60 202.3 0.0 1.6e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.17 KFH48388.1 - 2e-24 85.7 0.0 3.7e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 Pkinase PF00069.25 KFH48389.1 - 2.1e-37 128.9 0.0 3.4e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48389.1 - 8.7e-18 64.5 0.0 3.8e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFH48389.1 - 1e-06 28.9 0.1 4.8e-06 26.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH48389.1 - 0.0015 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFH48389.1 - 0.005 16.4 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFH48389.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFH48389.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KFH48389.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SDA1 PF05285.12 KFH48390.1 - 9.5e-96 321.2 37.4 9.5e-96 321.2 37.4 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KFH48390.1 - 1.6e-21 76.4 0.3 5.6e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain Dict-STAT-coil PF09267.10 KFH48390.1 - 0.058 13.8 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF2277 PF10041.9 KFH48390.1 - 0.94 9.9 4.0 4.1 7.8 0.1 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2277) DUF1249 PF06853.12 KFH48391.1 - 0.085 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) Imm57 PF15596.6 KFH48391.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 57 MFS_1 PF07690.16 KFH48392.1 - 3.7e-25 88.6 39.0 5.9e-25 87.9 39.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily JmjC PF02373.22 KFH48393.1 - 3.2e-38 130.7 0.5 9.8e-38 129.1 0.5 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFH48393.1 - 2.5e-20 72.7 6.9 4.5e-20 71.8 6.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFH48393.1 - 5.4e-19 68.2 7.5 5.4e-19 68.2 7.5 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KFH48393.1 - 6.1e-15 54.9 0.5 1.7e-14 53.5 0.5 1.8 1 0 0 1 1 1 1 jmjN domain PRP21_like_P PF12230.8 KFH48393.1 - 0.087 12.7 2.1 0.32 10.8 2.1 2.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Ala_racemase_N PF01168.20 KFH48394.1 - 1.9e-31 109.5 0.1 2.3e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KFH48394.1 - 6.9e-24 84.3 0.1 1.5e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KFH48394.1 - 0.073 12.7 3.3 0.69 9.5 2.1 2.4 2 1 1 3 3 3 0 Serine dehydratase alpha chain GTP_CH_N PF12471.8 KFH48394.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal ADH_zinc_N PF00107.26 KFH48398.1 - 3e-22 79.0 0.0 5.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFH48398.1 - 1.5e-21 76.3 2.8 2.3e-21 75.7 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH48398.1 - 1.8e-07 32.3 0.0 2.9e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFH48398.1 - 0.023 14.1 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFH48398.1 - 0.23 11.5 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2953 PF11167.8 KFH48399.1 - 0.035 14.2 0.3 0.2 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Arginosuc_synth PF00764.19 KFH48400.1 - 4.8e-45 154.5 0.0 7.3e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Amino_oxidase PF01593.24 KFH48400.1 - 2e-33 116.4 0.1 4.2e-33 115.3 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFH48400.1 - 7.4e-11 42.1 0.0 2e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Asn_synthase PF00733.21 KFH48400.1 - 0.00055 19.7 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Asparagine synthase Pyr_redox_2 PF07992.14 KFH48400.1 - 0.0049 16.1 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase QueC PF06508.13 KFH48400.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF1977 PF09320.11 KFH48401.1 - 1.5e-31 108.8 0.1 3.6e-31 107.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFH48401.1 - 1.2e-18 67.0 0.1 2e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KFH48402.1 - 5.1e-22 78.2 0.0 9.5e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48402.1 - 8e-08 32.3 13.7 1.5e-07 31.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KFH48402.1 - 0.0071 15.5 0.2 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TSC22 PF01166.18 KFH48402.1 - 0.18 12.1 0.5 0.37 11.1 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family NUDIX PF00293.28 KFH48403.1 - 1.6e-16 60.6 0.5 2e-16 60.2 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFH48403.1 - 0.00082 19.3 0.1 0.0018 18.3 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain PRIMA1 PF16101.5 KFH48403.1 - 8.8 6.4 6.9 16 5.6 6.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAD_binding_3 PF01494.19 KFH48404.1 - 1.5e-17 63.9 0.2 4.4e-10 39.3 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KFH48404.1 - 6e-07 28.9 0.1 1.1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFH48404.1 - 9.9e-06 25.7 0.2 2.3e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFH48404.1 - 3.3e-05 23.3 0.2 6.6e-05 22.3 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH48404.1 - 4.3e-05 23.2 0.5 0.0054 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFH48404.1 - 0.00065 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFH48404.1 - 0.0024 17.0 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KFH48404.1 - 0.0029 18.1 0.1 0.0071 16.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH48404.1 - 0.0057 15.4 0.2 0.0083 14.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KFH48404.1 - 0.0088 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFH48404.1 - 0.0096 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFH48404.1 - 0.021 13.7 0.0 0.29 10.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KFH48404.1 - 0.021 14.1 0.1 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KFH48404.1 - 0.028 13.7 0.2 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFH48404.1 - 0.1 11.7 0.6 0.73 8.8 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Tcp11 PF05794.13 KFH48406.1 - 4.4e-99 332.6 0.0 4.4e-99 332.6 0.0 2.2 2 0 0 2 2 2 1 T-complex protein 11 DUF4413 PF14372.6 KFH48406.1 - 0.068 13.5 0.5 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Methyltransf_2 PF00891.18 KFH48407.1 - 7.3e-08 32.0 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Fungal_trans_2 PF11951.8 KFH48408.1 - 6.3e-24 84.5 0.3 8.1e-24 84.1 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-TRAF PF02176.18 KFH48409.1 - 1e-10 42.2 26.7 1.7e-08 35.0 3.5 3.9 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFH48409.1 - 5.5e-09 35.7 5.7 5.5e-09 35.7 5.7 3.6 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH48409.1 - 1.4e-08 34.5 4.2 1.4e-08 34.5 4.2 3.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFH48409.1 - 5.4e-08 32.9 5.9 5.4e-08 32.9 5.9 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFH48409.1 - 1.8e-07 30.9 2.5 1.8e-07 30.9 2.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH48409.1 - 3.2e-07 30.3 7.9 3.2e-07 30.3 7.9 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH48409.1 - 5.4e-07 29.8 5.1 5.4e-07 29.8 5.1 3.8 2 1 1 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KFH48409.1 - 6.2e-06 26.1 2.9 6.2e-06 26.1 2.9 3.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 KFH48409.1 - 4.2e-05 23.9 9.0 4.2e-05 23.9 9.0 3.1 1 1 2 3 3 3 1 TRAF-like zinc-finger zf-Nse PF11789.8 KFH48409.1 - 0.013 15.3 2.7 0.013 15.3 2.7 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFH48409.1 - 0.047 13.6 2.3 0.14 12.0 2.3 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFH48409.1 - 0.058 13.5 0.5 0.058 13.5 0.5 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.16 KFH48409.1 - 0.073 13.0 24.5 0.13 12.2 0.2 3.8 3 1 2 5 5 5 0 Seven in absentia protein family DUF1664 PF07889.12 KFH48409.1 - 0.094 12.8 1.5 7 6.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prok-RING_4 PF14447.6 KFH48409.1 - 0.14 12.1 21.7 0.21 11.5 8.0 4.2 2 2 2 4 4 4 0 Prokaryotic RING finger family 4 ADH_zinc_N_2 PF13602.6 KFH48410.1 - 6.9e-20 72.5 0.0 1.1e-19 71.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH48410.1 - 1.1e-10 41.6 0.0 3.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ima1_N PF09779.9 KFH48412.1 - 3.3e-32 112.2 1.6 5.6e-32 111.4 1.6 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.7 KFH48412.1 - 0.02 14.9 2.4 0.02 14.9 2.4 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 KFH48412.1 - 0.023 14.7 3.2 1.5 8.9 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KFH48412.1 - 0.31 11.0 6.2 0.037 13.9 1.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain AAA PF00004.29 KFH48413.1 - 1.4e-43 148.5 0.0 2.2e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFH48413.1 - 5e-15 55.0 0.0 9.7e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFH48413.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFH48413.1 - 2.9e-07 30.8 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KFH48413.1 - 4.8e-07 29.6 2.3 1.2e-06 28.3 2.3 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KFH48413.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFH48413.1 - 4.3e-05 23.8 0.3 0.018 15.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFH48413.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFH48413.1 - 0.00062 20.3 0.1 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFH48413.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFH48413.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFH48413.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 KFH48413.1 - 0.0066 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC Prot_ATP_OB_N PF17758.1 KFH48413.1 - 0.0069 16.0 0.1 0.022 14.4 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KFH48413.1 - 0.0076 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFH48413.1 - 0.0097 15.8 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFH48413.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFH48413.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KFH48413.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFH48413.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFH48413.1 - 0.025 14.0 0.0 0.093 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 KFH48413.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFH48413.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFH48413.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFH48413.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFH48413.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KFH48413.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KFH48413.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH48413.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KFH48413.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain HR1 PF02185.16 KFH48413.1 - 0.45 10.7 3.2 0.91 9.7 2.6 1.8 1 1 0 1 1 1 0 Hr1 repeat Pkinase PF00069.25 KFH48415.1 - 7.4e-31 107.5 0.0 1.1e-29 103.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48415.1 - 9e-16 57.9 0.0 1.4e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48415.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ADH_N PF08240.12 KFH48416.1 - 8e-05 22.5 0.6 0.00046 20.0 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFH48416.1 - 0.00036 21.6 0.2 0.0045 18.0 0.1 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_4 PF08386.10 KFH48417.1 - 2.2e-18 66.3 0.0 5.3e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KFH48417.1 - 8.4e-13 48.6 0.0 8e-09 35.5 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 KFH48418.1 - 4e-33 114.8 29.9 6.3e-33 114.2 29.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Nitrate_red_del PF02613.15 KFH48419.1 - 0.18 11.8 1.5 0.33 11.0 0.2 2.1 2 0 0 2 2 2 0 Nitrate reductase delta subunit DUF3080 PF11279.8 KFH48419.1 - 0.24 10.6 8.1 0.021 14.1 1.8 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3080) Pox_Ag35 PF03286.14 KFH48419.1 - 1.5 8.6 13.2 1 9.1 4.1 2.5 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Acetyltransf_6 PF13480.7 KFH48419.1 - 2.4 8.3 8.3 2.3 8.4 0.1 3.6 2 1 2 4 4 4 0 Acetyltransferase (GNAT) domain GTP_cyclohydroI PF01227.22 KFH48419.1 - 7.6 5.9 9.1 1.2 8.6 0.7 2.8 2 1 1 3 3 3 0 GTP cyclohydrolase I CAP PF00188.26 KFH48420.1 - 1.7e-17 64.4 0.5 4e-17 63.2 0.5 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family HET PF06985.11 KFH48423.1 - 4e-27 95.4 0.5 1e-26 94.1 0.5 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Utp8 PF10395.9 KFH48424.1 - 5.7e-09 35.1 0.0 1.1e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Utp8 family Aldo_ket_red PF00248.21 KFH48425.1 - 2.6e-30 105.7 0.0 6.2e-28 97.8 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family CDC24 PF06395.11 KFH48425.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Pyridoxal_deC PF00282.19 KFH48426.1 - 4.9e-75 252.6 0.0 7e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4431 PF14485.6 KFH48426.1 - 0.096 12.5 0.0 0.72 9.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4431) rRNA_proc-arch PF13234.6 KFH48427.1 - 1.9e-86 290.3 0.0 1.1e-85 287.8 0.0 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KFH48427.1 - 5.3e-52 175.8 2.3 1.4e-51 174.4 1.8 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KFH48427.1 - 6.8e-19 68.3 0.0 2.1e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH48427.1 - 4.6e-07 30.2 0.0 1.3e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48427.1 - 2e-05 24.6 0.0 6.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFH48427.1 - 0.002 18.4 0.0 0.067 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFH48427.1 - 0.025 13.7 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KFH48427.1 - 0.1 12.5 0.2 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Gln-synt_C-ter PF18318.1 KFH48427.1 - 0.42 10.5 2.0 7.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain SRP-alpha_N PF04086.13 KFH48427.1 - 6.8 6.5 17.5 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Aminotran_3 PF00202.21 KFH48428.1 - 9.8e-111 370.3 0.0 1.2e-110 369.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFH48428.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Acetyltransf_1 PF00583.25 KFH48429.1 - 3.3e-06 27.3 0.0 2.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH48429.1 - 6.9e-06 26.4 0.1 0.00058 20.2 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH48429.1 - 3.3e-05 23.8 0.0 0.0002 21.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH48429.1 - 5.3e-05 23.3 0.1 0.0046 17.0 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH48429.1 - 0.00036 20.4 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein PPR_2 PF13041.6 KFH48430.1 - 5.9e-16 58.4 1.2 7.4e-05 22.9 0.0 5.0 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 KFH48430.1 - 3.9e-10 39.3 10.8 0.00013 22.0 0.0 5.4 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 KFH48430.1 - 3.4e-09 36.6 0.2 0.00036 20.5 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFH48430.1 - 0.00013 21.4 0.2 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFH48430.1 - 0.002 17.8 5.3 4.1 7.2 0.1 4.4 4 0 0 4 4 4 2 PPR repeat WLM PF08325.10 KFH48431.1 - 1.2e-48 165.8 0.1 1.2e-48 165.8 0.1 1.5 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KFH48431.1 - 6.3e-05 23.1 0.6 0.00015 21.9 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 KFH48431.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 SprT-like PF10263.9 KFH48431.1 - 0.068 13.0 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DIT1_PvcA PF05141.12 KFH48432.1 - 1.4e-93 313.4 0.0 1.8e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KFH48432.1 - 5.8e-21 75.5 0.0 1e-20 74.7 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF5470 PF17564.2 KFH48432.1 - 0.23 11.7 2.5 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Cullin_binding PF03556.15 KFH48433.1 - 3.8e-33 114.5 10.0 5.2e-33 114.0 10.0 1.2 1 0 0 1 1 1 1 Cullin binding Spt20 PF12090.8 KFH48434.1 - 1.2e-43 149.4 0.4 1.2e-43 149.4 0.4 2.9 3 1 0 3 3 3 2 Spt20 family TERB2 PF15101.6 KFH48434.1 - 8.9 6.3 14.8 21 5.1 14.8 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Aminotran_1_2 PF00155.21 KFH48435.1 - 7.8e-69 232.6 0.0 1e-68 232.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFH48435.1 - 0.00011 21.6 0.1 0.00048 19.6 0.0 1.9 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KFH48435.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFH48435.1 - 0.0025 16.4 0.0 0.0048 15.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFH48435.1 - 0.014 14.3 0.0 0.031 13.2 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Amidohydro_3 PF07969.11 KFH48436.1 - 7.7e-66 223.5 0.3 8.9e-66 223.3 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KFH48436.1 - 4.1e-07 29.6 0.0 0.061 12.6 0.0 3.6 2 1 0 2 2 2 2 Amidohydrolase family ER_lumen_recept PF00810.18 KFH48437.1 - 1.4e-53 181.7 6.6 2.1e-53 181.1 6.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFH48437.1 - 0.46 10.3 12.5 0.77 9.6 0.2 3.6 3 1 1 4 4 4 0 PQ loop repeat CorA PF01544.18 KFH48438.1 - 2.1e-27 96.2 4.1 7.3e-24 84.6 1.3 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Alg14 PF08660.11 KFH48439.1 - 5.4e-39 133.9 0.0 7.7e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Amidase PF01425.21 KFH48440.1 - 3.7e-57 194.3 0.8 1.7e-55 188.8 0.8 2.6 1 1 0 1 1 1 1 Amidase ADH_N PF08240.12 KFH48441.1 - 1.1e-29 102.5 1.0 2e-29 101.7 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH48441.1 - 8.1e-28 97.0 0.4 1.3e-27 96.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH48441.1 - 2.1e-08 35.3 0.1 3.5e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFH48441.1 - 1.7e-07 30.9 0.4 2.6e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KFH48441.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.6 KFH48441.1 - 0.00029 21.3 0.8 0.00047 20.6 0.1 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFH48441.1 - 0.0092 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFH48441.1 - 0.06 13.9 0.8 0.39 11.3 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFH48441.1 - 0.061 12.6 0.2 0.097 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Y_phosphatase2 PF03162.13 KFH48442.1 - 2.3e-43 147.6 0.0 3.4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KFH48442.1 - 1.6e-07 31.5 0.0 5.2e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFH48442.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Arrestin_C PF02752.22 KFH48443.1 - 1.7e-15 57.7 0.0 4e-14 53.2 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFH48443.1 - 5.8e-06 26.4 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain FbpC_C_terminal PF17845.1 KFH48443.1 - 0.061 13.4 0.4 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain SesA PF17107.5 KFH48444.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Aminotran_5 PF00266.19 KFH48446.1 - 1.2e-29 103.4 0.0 1.6e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V IPK PF03770.16 KFH48447.1 - 1.2e-56 191.7 0.0 2.2e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Fungal_trans_2 PF11951.8 KFH48448.1 - 1.7e-56 191.7 0.6 2.9e-56 190.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48448.1 - 2.2e-07 30.9 16.2 3.9e-07 30.1 16.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MotA_ExbB PF01618.16 KFH48448.1 - 0.033 13.9 0.4 0.095 12.4 0.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family SUIM_assoc PF16619.5 KFH48448.1 - 0.5 10.5 6.5 1.2 9.2 6.5 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FMO-like PF00743.19 KFH48449.1 - 1.8e-32 112.5 0.0 2.5e-21 75.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFH48449.1 - 6.7e-12 45.2 0.0 8.8e-09 35.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFH48449.1 - 8.7e-12 44.9 0.2 1.9e-08 34.0 0.2 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH48449.1 - 3e-06 26.7 0.1 0.00012 21.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH48449.1 - 0.00036 20.6 0.1 0.083 12.9 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding TOBE_2 PF08402.10 KFH48449.1 - 0.00082 19.5 0.1 0.0055 16.9 0.0 2.1 2 0 0 2 2 2 1 TOBE domain NAD_binding_8 PF13450.6 KFH48449.1 - 0.0015 18.8 0.0 0.0058 16.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH48449.1 - 0.014 15.9 0.3 1.4 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH48449.1 - 0.018 14.6 0.1 0.39 10.3 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF4147 PF13660.6 KFH48449.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Zn_clus PF00172.18 KFH48451.1 - 6.5e-09 35.8 7.2 1.1e-08 35.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH48451.1 - 0.00054 19.1 0.1 0.0023 17.0 0.0 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF5412 PF17428.2 KFH48452.1 - 0.055 13.3 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5412) CRCB PF02537.15 KFH48453.1 - 4.4e-39 132.7 12.2 8.6e-23 80.5 8.5 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Glycos_transf_1 PF00534.20 KFH48454.1 - 1.4e-33 115.9 0.0 3.4e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFH48454.1 - 5.5e-17 62.5 0.1 1.9e-16 60.7 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFH48454.1 - 3.4e-16 59.7 0.7 1.1e-15 58.1 0.7 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFH48454.1 - 9.9e-08 32.6 7.4 1.2e-07 32.4 0.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFH48454.1 - 4.1e-05 23.9 0.0 7.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KFH48454.1 - 0.002 18.2 0.4 0.52 10.3 0.0 2.5 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus LicD PF04991.13 KFH48455.1 - 3.6e-22 79.6 2.7 4.1e-16 59.8 1.7 2.3 1 1 1 2 2 2 2 LicD family P21-Arc PF04062.14 KFH48456.1 - 2.4e-71 239.3 0.0 2.7e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit RdRP PF05183.12 KFH48457.1 - 3.8e-102 342.9 0.0 8.6e-74 249.2 0.0 4.5 2 2 1 3 3 3 3 RNA dependent RNA polymerase zf-UBP PF02148.19 KFH48457.1 - 0.041 14.2 0.3 0.31 11.4 0.4 2.2 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein FAD_binding_9 PF08021.11 KFH48457.1 - 0.14 12.4 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Ank_4 PF13637.6 KFH48458.1 - 1.5e-21 76.4 0.3 4.1e-06 27.2 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH48458.1 - 2.4e-21 76.1 0.0 3.7e-12 46.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH48458.1 - 2e-20 70.7 0.1 0.00055 20.2 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFH48458.1 - 2.9e-17 62.5 3.5 1.7e-08 34.5 0.2 5.2 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH48458.1 - 1.5e-15 56.9 1.3 3.4e-05 24.1 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat TFIIE_beta PF02186.15 KFH48458.1 - 0.025 14.9 0.0 0.084 13.2 0.0 1.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain TFIID_30kDa PF03540.13 KFH48459.1 - 5.2e-26 90.3 0.3 8.6e-26 89.7 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KFH48459.1 - 5 7.7 7.4 13 6.4 7.4 1.8 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Goodbye PF17109.5 KFH48460.1 - 5.9e-12 46.1 0.1 5.9e-12 46.1 0.1 2.2 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KFH48460.1 - 1.8e-06 28.3 0.6 7.6e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFH48460.1 - 1.9e-06 28.4 0.3 4.4e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KFH48460.1 - 1.9e-06 27.9 0.0 5.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 KFH48460.1 - 4e-05 24.1 5.0 0.068 13.7 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH48460.1 - 6e-05 22.6 0.4 0.00016 21.2 0.4 1.7 1 0 0 1 1 1 1 MalT-like TPR region AFG1_ATPase PF03969.16 KFH48460.1 - 0.04 12.8 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.22 KFH48460.1 - 0.052 12.7 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain TPR_2 PF07719.17 KFH48460.1 - 0.13 12.5 3.4 5.8 7.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Torsin PF06309.11 KFH48460.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Torsin Unstab_antitox PF09720.10 KFH48460.1 - 0.23 11.5 1.3 36 4.5 0.4 3.1 2 0 0 2 2 2 0 Putative addiction module component Cluap1 PF10234.9 KFH48460.1 - 0.69 9.3 6.9 4.1 6.7 4.9 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 TPR_14 PF13428.6 KFH48460.1 - 1.6 9.7 11.9 21 6.3 0.4 5.5 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFH48460.1 - 5.6 7.3 6.6 30 5.0 0.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KFH48461.1 - 3.8e-08 33.3 10.8 5.5e-08 32.8 10.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFH48462.1 - 3.8e-49 167.4 0.1 3.1e-33 115.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48462.1 - 1.5e-21 76.9 0.2 2.9e-19 69.4 0.1 3.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48462.1 - 4.4e-05 23.0 0.0 0.00013 21.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFH48462.1 - 0.017 15.1 0.1 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTP_transf_like PF01467.26 KFH48464.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase-like MFS_1 PF07690.16 KFH48465.1 - 8.3e-16 57.9 38.5 3.2e-15 55.9 33.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48465.1 - 3.5e-05 22.9 9.0 3.5e-05 22.9 9.0 3.0 2 1 2 4 4 4 1 Sugar (and other) transporter Glyco_hydro_12 PF01670.16 KFH48466.1 - 8.8e-36 123.9 6.2 1e-35 123.7 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_31 PF01055.26 KFH48467.1 - 2.4e-93 313.7 0.0 3e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFH48467.1 - 1.3e-12 47.8 0.2 8.5e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Cyclase PF04199.13 KFH48468.1 - 1e-14 54.9 0.1 4.8e-14 52.7 0.0 1.8 1 1 1 2 2 2 1 Putative cyclase SLD5_C PF16922.5 KFH48468.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Striatin PF08232.12 KFH48469.1 - 7.1e-41 140.4 6.1 1.5e-40 139.3 6.1 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 KFH48469.1 - 5e-24 84.1 18.5 2.4e-05 25.0 0.2 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48469.1 - 4.2e-05 23.8 0.1 3.8 7.9 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ADH_N_2 PF16884.5 KFH48469.1 - 0.022 14.7 1.8 0.035 14.0 0.0 2.2 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase CALCOCO1 PF07888.11 KFH48469.1 - 0.11 11.4 6.2 0.17 10.8 6.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ge1_WD40 PF16529.5 KFH48469.1 - 0.2 10.6 0.0 0.65 8.9 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4407 PF14362.6 KFH48469.1 - 9.5 5.5 7.4 15 4.8 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XPA_C PF05181.12 KFH48471.1 - 2.3e-26 91.5 1.6 4.7e-26 90.5 1.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus ArfGap PF01412.18 KFH48471.1 - 0.0085 16.2 1.1 0.0085 16.2 1.1 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf FRG1 PF06229.12 KFH48471.1 - 0.018 14.7 0.8 0.04 13.6 0.8 1.6 1 0 0 1 1 1 0 FRG1-like domain zf-C3HC4_3 PF13920.6 KFH48471.1 - 2 8.3 7.6 0.35 10.8 3.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XPA_N PF01286.18 KFH48471.1 - 2.3 8.4 12.3 0.14 12.2 6.4 2.0 2 0 0 2 2 2 0 XPA protein N-terminal Beta-lactamase PF00144.24 KFH48472.1 - 7e-52 176.7 1.9 9.5e-52 176.3 1.9 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFH48472.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Gin PF10764.9 KFH48473.1 - 0.037 14.0 0.4 0.057 13.4 0.4 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Neur_chan_memb PF02932.16 KFH48474.1 - 0.37 10.8 2.1 0.88 9.6 2.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PTCB-BRCT PF12738.7 KFH48476.1 - 2.8e-41 139.3 0.4 4.1e-18 65.1 0.2 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KFH48476.1 - 4.5e-39 132.7 0.0 1.8e-13 50.7 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFH48476.1 - 2.4e-15 56.7 0.0 0.00027 21.3 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFH48476.1 - 2e-08 34.4 1.4 0.012 15.9 0.0 4.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KFH48476.1 - 0.0047 17.0 0.0 1.4 9.0 0.0 3.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 KFH48477.1 - 8e-22 77.6 57.4 2.6e-15 56.2 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ECH_1 PF00378.20 KFH48478.1 - 4.2e-22 78.7 0.0 5.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH48478.1 - 3.7e-05 23.4 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Histone PF00125.24 KFH48479.1 - 8.6e-18 65.0 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFH48479.1 - 7.7e-13 47.9 0.1 1.9e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFH48479.1 - 3.4e-05 24.0 0.0 5.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C48 PF02902.19 KFH48480.1 - 0.22 11.3 0.2 0.4 10.5 0.2 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain APH PF01636.23 KFH48481.1 - 0.0011 19.0 0.0 0.0039 17.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family HET PF06985.11 KFH48483.1 - 2.2e-27 96.2 1.0 1.2e-22 80.9 0.7 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 KFH48483.1 - 7.1e-14 51.7 1.4 6.3e-11 42.3 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH48483.1 - 3.6e-12 46.7 0.1 1.1e-11 45.2 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48483.1 - 3.7e-08 33.8 0.3 2.5e-06 27.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFH48483.1 - 9.1e-08 32.2 0.1 0.046 14.2 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFH48483.1 - 1.7e-06 27.9 0.0 0.12 13.0 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat DUF4530 PF15039.6 KFH48483.1 - 0.21 11.7 0.6 0.51 10.5 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF445 PF04286.12 KFH48484.1 - 0.00067 19.6 9.7 0.0008 19.3 4.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Alpha_Helical PF18489.1 KFH48484.1 - 0.043 14.0 0.7 0.13 12.5 0.7 1.8 1 0 0 1 1 1 0 Alpha helical domain Ge1_WD40 PF16529.5 KFH48484.1 - 0.14 11.1 0.0 0.68 8.8 0.0 1.9 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1754 PF08555.10 KFH48484.1 - 1.8 9.4 0.0 1.8 9.4 0.0 4.4 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Alpha_L_fucos PF01120.17 KFH48485.1 - 0.047 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase OmdA PF13376.6 KFH48486.1 - 1.9e-19 69.4 0.5 2.5e-19 69.1 0.5 1.1 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated bZIP_1 PF00170.21 KFH48487.1 - 1.9e-08 34.3 9.8 3.9e-08 33.3 9.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFH48487.1 - 0.00054 20.0 9.8 0.002 18.2 9.8 2.0 1 1 0 1 1 1 1 Basic region leucine zipper ZapB PF06005.12 KFH48487.1 - 0.15 12.6 0.2 0.15 12.6 0.2 3.3 4 0 0 4 4 4 0 Cell division protein ZapB FAM193_C PF15914.5 KFH48487.1 - 0.15 11.8 0.4 0.38 10.5 0.4 1.6 1 0 0 1 1 1 0 FAM193 family C-terminal DivIC PF04977.15 KFH48487.1 - 1.6 8.6 6.8 0.76 9.6 0.9 2.6 2 0 0 2 2 2 0 Septum formation initiator COesterase PF00135.28 KFH48488.1 - 6.1e-81 272.8 0.0 8.2e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFH48488.1 - 9.6e-05 22.3 0.2 0.00076 19.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Steroid_dh PF02544.16 KFH48489.1 - 1.5e-19 70.5 0.1 1.2e-18 67.6 0.1 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFH48489.1 - 0.00013 21.6 1.7 0.00018 21.1 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ADH_zinc_N PF00107.26 KFH48490.1 - 1.1e-22 80.4 0.1 1.7e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFH48490.1 - 4.6e-20 73.0 0.0 7.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFH48490.1 - 3e-06 27.1 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KFH48490.1 - 0.00012 21.9 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Condensation PF00668.20 KFH48491.1 - 0 2089.1 0.0 1e-84 284.9 0.0 9.3 9 0 0 9 9 9 9 Condensation domain AMP-binding PF00501.28 KFH48491.1 - 0 1886.7 0.0 2.2e-73 247.3 0.0 9.2 8 1 0 8 8 8 8 AMP-binding enzyme PP-binding PF00550.25 KFH48491.1 - 7.7e-100 327.3 14.8 4.9e-12 46.0 0.0 9.8 9 0 0 9 9 9 8 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH48491.1 - 6.6e-52 174.4 12.8 3e-07 31.3 0.0 12.2 11 0 0 11 11 11 9 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KFH48491.1 - 8.3e-16 58.5 0.0 0.00097 19.8 0.0 4.5 4 0 0 4 4 4 3 Methyltransferase domain Methyltransf_23 PF13489.6 KFH48491.1 - 3.7e-13 49.6 0.0 0.005 16.7 0.0 5.9 6 0 0 6 6 6 3 Methyltransferase domain Methyltransf_11 PF08241.12 KFH48491.1 - 3.2e-11 43.7 0.0 0.013 16.1 0.0 4.2 3 0 0 3 3 3 3 Methyltransferase domain Methyltransf_31 PF13847.6 KFH48491.1 - 5.5e-10 39.2 0.0 0.049 13.4 0.0 3.7 3 0 0 3 3 3 3 Methyltransferase domain DUF547 PF04784.14 KFH48491.1 - 3.6e-06 27.0 0.1 10 6.2 0.0 6.3 7 0 0 7 7 6 1 Protein of unknown function, DUF547 DUF2183 PF09949.9 KFH48491.1 - 0.1 12.9 0.0 21 5.5 0.0 4.0 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2183) IF2_assoc PF08364.11 KFH48491.1 - 2.7 8.3 4.9 1.5e+02 2.7 0.0 5.2 6 0 0 6 6 6 0 Bacterial translation initiation factor IF-2 associated region SNF2_N PF00176.23 KFH48492.1 - 1.6e-69 234.3 0.0 2.2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFH48492.1 - 1.2e-25 89.2 0.0 2.3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFH48492.1 - 7.9e-16 58.4 0.0 1.9e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48492.1 - 8e-07 29.2 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KFH48492.1 - 0.00019 21.2 5.4 0.00031 20.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFH48492.1 - 0.00062 19.6 5.0 0.0013 18.6 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH48492.1 - 0.0011 18.8 7.2 0.002 17.9 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFH48492.1 - 0.012 16.0 7.9 0.026 14.8 7.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFH48492.1 - 0.017 15.1 7.6 0.035 14.1 7.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFH48492.1 - 0.087 12.8 6.3 0.25 11.3 6.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain ERAP1_C PF11838.8 KFH48493.1 - 1.3e-84 284.4 0.0 3.3e-84 283.1 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFH48493.1 - 2.2e-81 272.6 2.9 3.8e-81 271.8 2.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFH48493.1 - 7e-45 153.5 0.4 7e-45 153.5 0.4 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 KFH48493.1 - 0.027 14.5 0.2 0.15 12.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF45 DUF2808 PF10989.8 KFH48493.1 - 0.043 13.8 0.4 0.21 11.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2808) Mito_carr PF00153.27 KFH48494.1 - 6.9e-46 154.1 6.8 7.6e-18 64.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KFH48495.1 - 1.1e-32 113.4 28.9 1.1e-32 113.4 28.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_Ca_ex PF01699.24 KFH48496.1 - 3.2e-20 72.6 30.6 8.5e-16 58.3 13.0 4.0 4 1 1 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KFH48496.1 - 2.7e-16 60.0 11.5 2.7e-16 60.0 11.5 3.8 3 0 0 3 3 3 1 Inner membrane component domain SPO22 PF08631.10 KFH48498.1 - 9.9e-55 186.0 5.5 6.8e-54 183.2 0.4 3.6 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KFH48498.1 - 0.79 10.1 10.4 2.9 8.2 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat BC10 PF06726.12 KFH48499.1 - 7.3e-18 64.6 10.9 1e-17 64.1 10.9 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Ank_2 PF12796.7 KFH48500.1 - 2.8e-14 53.5 0.3 2e-10 41.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48500.1 - 4.1e-14 52.8 4.6 4.4e-05 23.9 0.0 6.2 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH48500.1 - 1.4e-13 50.6 3.9 1.2e-06 28.7 0.3 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFH48500.1 - 9.5e-13 48.1 7.2 3.9e-07 30.2 0.4 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH48500.1 - 1.1e-08 34.7 3.6 3.9e-05 23.7 0.1 5.5 6 1 0 6 6 6 1 Ankyrin repeat Y_phosphatase PF00102.27 KFH48501.1 - 1.9e-59 201.1 0.2 2.1e-33 115.8 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KFH48501.1 - 2.5e-12 47.3 0.0 5.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KFH48501.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFH48501.1 - 0.073 12.9 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CCAP PF11105.8 KFH48501.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a KGG PF10685.9 KFH48502.1 - 1.5e-25 88.7 16.5 5.6e-11 42.3 0.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif DUF2474 PF10617.9 KFH48503.1 - 3.3 7.7 6.2 3.6 7.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Cellulase PF00150.18 KFH48504.1 - 1e-51 176.0 4.1 1.2e-51 175.8 4.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KFH48504.1 - 0.00043 20.0 0.5 0.00056 19.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) DUF5103 PF17116.5 KFH48504.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) Fungal_trans PF04082.18 KFH48505.1 - 4.1e-17 62.1 0.7 6.1e-17 61.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFH48505.1 - 7e-08 32.5 12.2 0.0013 19.1 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH48505.1 - 3.5e-07 30.4 12.1 6.2e-07 29.6 6.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain DUF2722 PF10846.8 KFH48505.1 - 0.00066 18.7 10.4 0.002 17.2 10.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FAM91_C PF14648.6 KFH48505.1 - 0.0011 18.0 2.8 0.0017 17.3 2.8 1.2 1 0 0 1 1 1 1 FAM91 C-terminus zf-C2H2_4 PF13894.6 KFH48505.1 - 0.0013 19.4 12.3 0.1 13.5 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Spt20 PF12090.8 KFH48505.1 - 0.0014 18.2 17.5 0.0035 17.0 17.5 1.6 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 KFH48505.1 - 0.0016 18.5 11.3 0.0016 18.5 11.3 2.9 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 KFH48505.1 - 0.014 14.4 4.1 0.027 13.5 4.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-C2H2_jaz PF12171.8 KFH48505.1 - 0.043 14.1 3.5 0.44 10.9 0.4 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFH48505.1 - 0.44 10.8 2.4 1.3 9.3 2.4 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain DDHD PF02862.17 KFH48505.1 - 0.72 10.0 5.7 0.16 12.1 1.0 2.1 2 0 0 2 2 2 0 DDHD domain zf-met PF12874.7 KFH48505.1 - 2.3 8.7 4.9 0.64 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CNDH2_C PF16858.5 KFH48505.1 - 3.2 7.5 12.2 0.073 12.9 5.4 1.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ndc1_Nup PF09531.10 KFH48505.1 - 6 5.4 10.0 0.18 10.4 0.4 2.4 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 KFH48505.1 - 6.3 6.1 9.7 12 5.1 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.6 KFH48505.1 - 6.4 4.6 23.1 14 3.4 23.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S9 PF00326.21 KFH48506.1 - 1.3e-15 57.5 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFH48506.1 - 5.2e-09 36.3 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KFH48506.1 - 1.7e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFH48506.1 - 8.2e-06 25.6 0.0 0.0017 18.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFH48506.1 - 0.00046 19.5 0.0 0.032 13.5 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFH48506.1 - 0.0023 18.6 0.2 0.003 18.2 0.2 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 KFH48506.1 - 0.0048 16.3 0.1 0.23 10.8 0.1 2.6 2 1 0 2 2 2 1 Secretory lipase FSH1 PF03959.13 KFH48506.1 - 0.007 16.1 0.0 0.0083 15.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1989 PF09347.10 KFH48507.1 - 7.7e-65 217.6 0.0 9.6e-65 217.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RTA1 PF04479.13 KFH48508.1 - 2.5e-35 122.0 6.4 7.9e-33 113.8 6.4 2.2 1 1 0 1 1 1 1 RTA1 like protein UPF0182 PF03699.13 KFH48508.1 - 0.28 9.2 2.0 0.41 8.7 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4131 PF13567.6 KFH48508.1 - 3 7.5 5.6 1.8 8.2 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1980 PF09323.10 KFH48508.1 - 3.4 7.6 6.1 0.61 10.0 1.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Alk_phosphatase PF00245.20 KFH48509.1 - 1.9e-102 343.3 0.0 2.4e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFH48509.1 - 0.00017 21.1 0.1 0.00035 20.0 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1294 PF06961.13 KFH48509.1 - 0.089 13.1 0.2 0.23 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) DUF4246 PF14033.6 KFH48510.1 - 1.5e-168 561.6 3.2 1.8e-168 561.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KFH48510.1 - 0.0063 16.9 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF2271 PF10029.9 KFH48510.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) MCPVI PF02993.14 KFH48511.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_S19 PF00203.21 KFH48512.1 - 1.6e-24 85.6 0.0 1.9e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 ABC_membrane PF00664.23 KFH48513.1 - 5.6e-90 301.7 34.5 3.1e-46 158.2 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFH48513.1 - 2.3e-68 228.9 0.0 1.1e-32 113.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFH48513.1 - 9.4e-13 48.1 5.1 1.7e-05 24.4 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFH48513.1 - 2e-09 38.1 2.6 0.00013 22.4 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KFH48513.1 - 3.6e-07 29.3 2.6 0.011 14.6 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KFH48513.1 - 5.8e-07 29.2 0.2 0.024 14.4 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KFH48513.1 - 1e-06 29.0 2.5 0.016 15.5 0.2 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFH48513.1 - 1.8e-06 27.9 0.0 0.074 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KFH48513.1 - 2.6e-06 27.2 0.0 0.018 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFH48513.1 - 2.4e-05 24.3 0.0 4.3 7.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFH48513.1 - 0.00017 21.6 0.0 0.51 10.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KFH48513.1 - 0.00063 20.2 2.3 1.4 9.3 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFH48513.1 - 0.0007 19.4 1.2 0.43 10.3 0.0 3.8 3 2 0 3 3 3 1 AAA domain Rad17 PF03215.15 KFH48513.1 - 0.0007 19.6 0.1 0.83 9.5 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain SbcCD_C PF13558.6 KFH48513.1 - 0.00083 19.5 0.7 5.4 7.3 0.2 3.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KFH48513.1 - 0.0014 18.2 0.1 0.91 9.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KFH48513.1 - 0.0019 18.5 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFH48513.1 - 0.0063 16.7 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFH48513.1 - 0.0083 16.7 0.0 3.8 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFH48513.1 - 0.01 15.6 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 KFH48513.1 - 0.01 15.0 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 KFH48513.1 - 0.019 15.4 0.0 5.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KFH48513.1 - 0.02 15.4 0.5 8.1 6.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFH48513.1 - 0.055 13.6 0.1 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KFH48513.1 - 0.06 13.4 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 KFH48513.1 - 0.086 12.8 0.0 18 5.2 0.0 3.0 3 0 0 3 3 2 0 NACHT domain ATP-synt_ab PF00006.25 KFH48513.1 - 0.086 12.5 0.2 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Dala_Dala_lig_N PF01820.21 KFH48513.1 - 0.12 12.8 0.0 8.9 6.8 0.0 3.0 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Zeta_toxin PF06414.12 KFH48513.1 - 0.15 11.3 0.0 22 4.2 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin FumaraseC_C PF10415.9 KFH48513.1 - 0.72 10.3 2.7 18 5.8 0.4 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus ApbA_C PF08546.11 KFH48514.1 - 7.8e-32 110.1 0.0 1.2e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFH48514.1 - 9.8e-24 83.7 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 KFH48514.1 - 0.015 15.9 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain Sacchrp_dh_NADP PF03435.18 KFH48514.1 - 0.025 14.8 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KFH48514.1 - 0.12 11.9 0.5 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFH48514.1 - 0.19 11.8 0.4 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Chorismate_synt PF01264.21 KFH48515.1 - 4.4e-140 466.0 0.0 5e-140 465.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF2786 PF10979.8 KFH48515.1 - 5 7.1 5.8 1.3 9.0 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) EpuA PF11772.8 KFH48516.1 - 0.73 9.6 5.8 1.5 8.6 5.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta KH_6 PF15985.5 KFH48517.1 - 0.026 14.9 0.1 0.064 13.6 0.1 1.7 1 0 0 1 1 1 0 KH domain AAA PF00004.29 KFH48518.1 - 1.2e-08 35.5 0.9 5.8e-07 30.0 2.5 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH48518.1 - 9.3e-06 26.1 0.0 3.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFH48518.1 - 0.00013 22.5 0.0 0.00043 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFH48518.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 KFH48518.1 - 0.0064 16.4 0.1 0.25 11.3 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KFH48518.1 - 0.0072 16.6 0.2 0.022 15.1 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFH48518.1 - 0.011 16.1 1.0 0.037 14.4 1.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFH48518.1 - 0.013 15.7 0.1 0.031 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH48518.1 - 0.026 13.8 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.12 KFH48518.1 - 0.028 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFH48518.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFH48518.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ATPase_2 PF01637.18 KFH48518.1 - 0.17 11.8 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ufd2P_core PF10408.9 KFH48519.1 - 3.1e-212 706.6 8.2 4.3e-212 706.1 8.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFH48519.1 - 1.3e-26 92.6 0.5 5.3e-26 90.6 0.5 2.2 2 0 0 2 2 2 1 U-box domain Efg1 PF10153.9 KFH48519.1 - 0.093 13.1 7.1 0.058 13.8 1.1 2.6 2 0 0 2 2 2 0 rRNA-processing protein Efg1 CCDC-167 PF15188.6 KFH48519.1 - 0.27 11.6 6.3 0.21 12.0 0.9 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Abhydrolase_3 PF07859.13 KFH48520.1 - 4.7e-33 114.8 0.0 3.9e-21 75.9 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFH48520.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_35 PF01301.19 KFH48521.1 - 2.4e-85 286.9 0.4 4.7e-85 286.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KFH48521.1 - 3e-59 199.9 0.1 5.5e-59 199.0 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KFH48521.1 - 3.4e-50 169.4 1.3 1.3e-30 106.3 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KFH48521.1 - 1.2e-20 72.9 0.0 2.5e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KFH48521.1 - 5.1e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KFH48521.1 - 5.1e-06 26.1 0.1 0.00038 19.9 0.1 2.5 1 1 1 2 2 2 1 Beta-galactosidase DUF2407_C PF13373.6 KFH48522.1 - 4.7e-34 117.6 0.0 6.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KFH48522.1 - 5.3e-23 81.6 0.0 7.8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KFH48522.1 - 0.00023 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CN_hydrolase PF00795.22 KFH48523.1 - 8.2e-36 123.7 0.0 4.6e-29 101.6 0.0 2.5 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase FAD_binding_3 PF01494.19 KFH48524.1 - 2.6e-56 191.4 0.0 3.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFH48524.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KFH48524.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein zf-FPG_IleRS PF06827.14 KFH48525.1 - 0.14 12.1 0.3 0.45 10.4 0.3 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS MFS_1 PF07690.16 KFH48526.1 - 1.1e-38 133.1 29.3 1.1e-38 133.1 29.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48526.1 - 1e-06 27.9 7.6 1e-06 27.9 7.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Oxysterol_BP PF01237.18 KFH48528.1 - 1.2e-46 159.2 0.1 2.2e-38 132.1 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Bombolitin PF08096.11 KFH48528.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Bombolitin family TT_ORF1 PF02956.14 KFH48529.1 - 3.5 6.2 7.3 3.7 6.1 7.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 COX7C PF02935.16 KFH48530.1 - 1.9e-22 79.2 1.2 2.9e-22 78.7 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF4396 PF14342.6 KFH48531.1 - 8.7e-45 152.5 0.7 1.2e-44 152.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DMT_YdcZ PF04657.13 KFH48531.1 - 0.051 13.8 0.9 0.051 13.8 0.9 1.6 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ Aim19 PF10315.9 KFH48532.1 - 0.0076 16.5 0.4 0.012 15.9 0.3 1.5 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 LSM PF01423.22 KFH48533.1 - 6.4e-19 67.4 0.0 7.7e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.27 KFH48534.1 - 3.7e-19 69.0 0.0 7.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFH48534.1 - 3.1e-07 30.7 0.7 9e-07 29.2 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFH48534.1 - 0.00016 22.0 0.1 0.0004 20.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFH48534.1 - 0.0014 18.7 0.1 0.0047 17.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFH48534.1 - 0.13 12.4 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Dynamin family ATG27 PF09451.10 KFH48535.1 - 1.8e-92 309.9 0.0 2.2e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Ald_Xan_dh_C2 PF02738.18 KFH48536.1 - 4.6e-208 692.1 0.3 6.5e-208 691.6 0.3 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFH48536.1 - 5.7e-48 162.9 0.0 1.2e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFH48536.1 - 2.5e-33 114.7 0.4 6.3e-33 113.4 0.4 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KFH48536.1 - 1.2e-29 102.5 1.0 2.8e-29 101.3 0.1 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KFH48536.1 - 2.7e-29 101.0 0.1 5.8e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFH48536.1 - 6.5e-08 32.4 0.6 2.4e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KFH48536.1 - 0.016 15.2 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain GHMP_kinases_C PF08544.13 KFH48536.1 - 0.35 11.3 1.2 1.8 9.0 0.3 2.7 2 0 0 2 2 2 0 GHMP kinases C terminal UPRTase PF14681.6 KFH48537.1 - 9.9e-71 237.5 0.0 1.1e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFH48537.1 - 0.00034 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 KFH48537.1 - 0.094 12.0 0.0 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase MRP-S25 PF13741.6 KFH48538.1 - 6.9e-64 215.6 8.0 3.8e-60 203.3 1.6 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KFH48538.1 - 0.021 15.1 1.6 0.031 14.5 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Fungal_trans PF04082.18 KFH48539.1 - 3.2e-24 85.4 1.0 4.2e-22 78.4 0.0 2.9 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48539.1 - 1.7e-07 31.2 10.1 2.7e-07 30.6 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3848 PF12959.7 KFH48539.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) GFA PF04828.14 KFH48540.1 - 1.1e-17 64.1 3.5 2.3e-08 34.2 0.4 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme PHO4 PF01384.20 KFH48541.1 - 5.2e-113 377.5 13.0 6e-113 377.3 13.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family HNH_2 PF13391.6 KFH48542.1 - 1e-09 38.4 0.0 2.7e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease zf-C2H2 PF00096.26 KFH48543.1 - 0.0021 18.4 5.3 0.0021 18.4 5.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH48543.1 - 0.013 15.9 1.4 0.013 15.9 1.4 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH48543.1 - 0.14 13.1 0.5 0.14 13.1 0.5 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Ricin_B_lectin PF00652.22 KFH48544.1 - 2.3e-06 27.9 0.0 5.8e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DEC-1_N PF04625.13 KFH48544.1 - 8 5.4 8.0 11 4.8 8.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DAO PF01266.24 KFH48545.1 - 3.2e-29 102.6 2.5 3.7e-29 102.4 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFH48545.1 - 0.014 14.6 0.1 0.027 13.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH48545.1 - 0.097 12.9 0.2 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFH48545.1 - 0.15 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 KFH48546.1 - 7.3e-11 41.9 0.0 1.2e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Ras family Chs7 PF12271.8 KFH48547.1 - 1.9e-119 398.3 13.2 2.1e-119 398.1 13.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone UPF0242 PF06785.11 KFH48547.1 - 1.9 8.6 3.4 38 4.3 3.4 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4281 PF14108.6 KFH48547.1 - 4.4 7.7 11.4 0.12 12.8 4.2 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4281) ADH_zinc_N_2 PF13602.6 KFH48548.1 - 1.8e-26 93.7 0.1 3.1e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFH48548.1 - 2.8e-16 59.7 0.4 9.2e-16 58.0 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HATPase_c_3 PF13589.6 KFH48549.1 - 1.4e-16 60.5 0.0 2.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KFH48549.1 - 4.7e-08 32.9 0.0 3.2e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KFH48549.1 - 6.4e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gcd10p PF04189.13 KFH48551.1 - 1e-119 399.2 0.0 1.2e-119 398.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family zf-C2H2_8 PF15909.5 KFH48553.1 - 0.91 9.9 7.5 0.19 12.1 3.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KFH48553.1 - 0.99 10.0 7.6 0.44 11.1 1.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH48553.1 - 1.9 9.5 11.2 0.52 11.3 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pho88 PF10032.9 KFH48555.1 - 9.3e-82 272.7 0.1 1e-81 272.5 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) MINDY_DUB PF04424.13 KFH48556.1 - 3e-24 85.3 0.0 5.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Abhydrolase_2 PF02230.16 KFH48557.1 - 2.2e-21 76.7 0.0 2e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFH48557.1 - 0.00019 21.0 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFH48557.1 - 0.0093 15.6 0.1 9.2 5.8 0.0 3.0 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFH48557.1 - 0.032 14.1 0.0 0.58 10.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold ATP13 PF12921.7 KFH48558.1 - 2.9e-22 78.7 0.0 8.4e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression Clathrin PF00637.20 KFH48559.1 - 5.2e-22 78.3 3.5 1.8e-20 73.3 0.4 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 KFH48559.1 - 1.1e-15 57.6 0.3 2.4e-15 56.5 0.3 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KFH48559.1 - 6e-06 26.2 5.2 1.7e-05 24.8 5.2 1.8 1 1 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KFH48559.1 - 0.00056 19.8 1.7 0.001 19.0 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFH48559.1 - 0.00071 19.4 2.4 0.0016 18.2 2.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH48559.1 - 0.011 15.8 1.5 0.028 14.4 1.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFH48559.1 - 0.048 13.5 1.6 0.1 12.5 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RGS PF00615.19 KFH48559.1 - 0.083 13.2 0.2 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain zf-RING_2 PF13639.6 KFH48559.1 - 0.085 13.2 2.7 0.18 12.2 2.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 KFH48559.1 - 0.24 11.2 0.8 0.9 9.3 0.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KFH48559.1 - 0.35 10.9 1.3 0.87 9.7 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFH48559.1 - 0.43 10.9 2.1 1 9.7 2.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ank_2 PF12796.7 KFH48561.1 - 3.2e-07 30.9 0.0 7.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48561.1 - 2.5e-06 27.9 0.2 1.5e-05 25.4 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFH48561.1 - 1.4e-05 25.3 0.1 0.00028 21.2 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFH48561.1 - 0.0023 18.3 0.1 0.15 12.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KFH48561.1 - 0.1 13.0 0.1 0.66 10.4 0.1 2.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) LRR_4 PF12799.7 KFH48562.1 - 1.9e-23 82.1 35.0 1.9e-05 25.0 0.9 9.0 5 2 3 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH48562.1 - 3e-13 49.3 33.2 0.00057 19.6 3.9 7.0 5 1 2 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 KFH48562.1 - 6.3e-06 25.8 16.0 1.1 9.5 0.3 6.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_9 PF14580.6 KFH48562.1 - 9.9e-06 25.2 11.2 0.091 12.3 0.7 4.1 1 1 2 4 4 4 3 Leucine-rich repeat Nucleo_P87 PF07267.11 KFH48562.1 - 0.084 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_1 PF00561.20 KFH48563.1 - 1.3e-11 44.7 0.0 7.6e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH48563.1 - 1.5e-08 35.5 0.1 3.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFH48563.1 - 7.3e-07 28.2 0.0 1.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KFH48563.1 - 7.2e-06 25.4 0.0 1.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFH48563.1 - 0.00023 20.9 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 KFH48563.1 - 0.00056 21.0 0.2 1.4 10.1 0.0 2.7 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KFH48563.1 - 0.1 13.1 0.0 4.5 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) BPL_LplA_LipB PF03099.19 KFH48565.1 - 1.2e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HicA_toxin PF07927.12 KFH48565.1 - 0.0003 20.7 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, MFS_1 PF07690.16 KFH48566.1 - 7.5e-28 97.5 47.9 5e-22 78.3 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFH48567.1 - 1.4e-68 231.8 18.8 1.7e-68 231.5 18.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH48567.1 - 3.4e-22 78.9 46.6 3.4e-22 78.9 46.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48567.1 - 1.6e-08 33.8 18.0 6e-08 32.0 8.0 3.3 3 0 0 3 3 3 3 Sugar (and other) transporter LRR_6 PF13516.6 KFH48569.1 - 0.0033 17.4 5.6 0.12 12.5 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KFH48569.1 - 0.0049 16.6 10.3 0.046 13.5 0.0 4.8 5 1 1 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 KFH48569.1 - 0.011 16.1 7.8 1.8 9.1 0.0 5.8 5 2 2 8 8 8 0 Leucine Rich repeats (2 copies) PLDc_3 PF13918.6 KFH48570.1 - 0.038 13.6 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 PLD-like domain Cyclin PF08613.11 KFH48571.1 - 1.1e-11 45.3 0.0 2.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFH48571.1 - 6.9e-05 22.6 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain FSH1 PF03959.13 KFH48573.1 - 1.5e-35 122.8 0.0 1.9e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KFH48573.1 - 0.00042 20.0 0.1 0.85 9.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFH48573.1 - 0.1 12.4 1.1 6.3 6.5 0.3 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Cupin_7 PF12973.7 KFH48574.1 - 5.3e-07 29.5 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KFH48574.1 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DNA_ligase_A_M PF01068.21 KFH48575.1 - 5.1e-44 150.4 0.0 2.3e-43 148.2 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFH48575.1 - 2.2e-42 145.3 0.0 5.2e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KFH48575.1 - 4.4e-18 65.5 0.0 3.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KFH48575.1 - 5.4e-18 65.8 0.0 1.4e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KFH48575.1 - 1.1e-14 54.8 0.5 2.8e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KFH48575.1 - 1.7e-09 37.9 0.0 5.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KFH48575.1 - 2.7e-05 24.2 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KFH48575.1 - 0.0006 20.0 0.0 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 KFH48575.1 - 0.0091 15.8 0.0 0.84 9.4 0.0 2.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain MFS_1 PF07690.16 KFH48576.1 - 2.1e-32 112.5 27.4 2.1e-32 112.5 27.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48576.1 - 6e-06 25.4 8.0 6e-06 25.4 8.0 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter DUF3716 PF12511.8 KFH48577.1 - 1.1e-07 31.7 9.0 2.1e-07 30.9 9.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Plasmodium_Vir PF05795.11 KFH48577.1 - 1.7 8.0 3.0 3 7.2 3.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rrn6 PF10214.9 KFH48577.1 - 7.3 5.0 10.9 9.1 4.6 8.8 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DUF4887 PF16228.5 KFH48577.1 - 9.6 6.4 12.1 24 5.1 12.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DHquinase_I PF01487.15 KFH48578.1 - 8.1e-22 78.6 0.0 1.3e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFH48578.1 - 3.6e-10 40.2 0.1 6.1e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KFH48578.1 - 9.7e-10 38.0 0.1 2.1e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_dh_N PF08501.11 KFH48578.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KFH48578.1 - 1.6e-06 28.3 0.0 3.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KFH48578.1 - 0.00014 22.1 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain OCD_Mu_crystall PF02423.15 KFH48578.1 - 0.026 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ABC_tran PF00005.27 KFH48578.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFH48578.1 - 0.083 13.3 0.7 1.1 9.6 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.6 KFH48578.1 - 0.092 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFH48578.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Homeobox_KN PF05920.11 KFH48579.1 - 4.3e-14 52.1 0.9 1e-13 50.9 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KFH48579.1 - 3.1e-10 40.0 11.5 5.8e-06 26.2 0.4 4.7 5 1 0 5 5 5 3 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KFH48579.1 - 4.8e-05 23.1 0.2 0.00017 21.4 0.2 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KFH48579.1 - 0.0021 18.8 4.3 0.0021 18.8 4.3 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH48579.1 - 0.0089 16.4 13.7 0.065 13.7 4.2 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFH48579.1 - 0.26 11.6 2.5 0.77 10.1 2.5 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFH48579.1 - 0.75 10.2 6.6 14 6.0 0.1 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) BIR PF00653.21 KFH48579.1 - 7 7.4 8.5 5.1 7.8 0.1 3.3 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain zf-FCS PF06467.14 KFH48579.1 - 8.2 6.5 7.7 2.8 7.9 1.0 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif 2OG-Fe_Oxy_2 PF10014.9 KFH48580.1 - 1.8e-47 161.6 1.3 2.2e-47 161.3 1.3 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase PS_pyruv_trans PF04230.13 KFH48580.1 - 0.2 11.6 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase CoA_transf_3 PF02515.17 KFH48581.1 - 6.9e-62 209.7 0.0 2.7e-61 207.8 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III DUF1751 PF08551.10 KFH48582.1 - 5.6e-28 97.4 4.7 1.2e-27 96.4 4.7 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KFH48582.1 - 0.0035 17.4 12.2 0.0062 16.5 12.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1600 PF07667.11 KFH48582.1 - 0.5 10.6 6.2 8 6.7 5.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Myb_DNA-binding PF00249.31 KFH48583.1 - 1.7e-15 56.9 2.0 2.7e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFH48583.1 - 1.2e-07 31.8 3.5 0.00074 19.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KFH48583.1 - 0.18 12.0 0.4 0.39 10.9 0.4 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SUIM_assoc PF16619.5 KFH48583.1 - 5.6 7.1 19.9 2.9 8.0 8.5 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PHD PF00628.29 KFH48584.1 - 4.6e-11 42.4 6.0 1.1e-10 41.2 6.0 1.7 1 0 0 1 1 1 1 PHD-finger DUF2520 PF10728.9 KFH48584.1 - 0.069 12.9 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) PHD_3 PF13922.6 KFH48584.1 - 0.11 12.9 0.2 0.36 11.2 0.2 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Erv26 PF04148.13 KFH48585.1 - 1.4e-89 299.3 1.6 1.7e-89 299.1 1.6 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 ThrE PF06738.12 KFH48586.1 - 1.1e-71 241.0 6.4 1.3e-68 231.0 2.9 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFH48586.1 - 1.5e-05 25.1 1.1 1.5e-05 25.1 1.1 3.4 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE CBM_19 PF03427.13 KFH48587.1 - 0.2 11.7 0.3 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Sugar_tr PF00083.24 KFH48588.1 - 7.1e-135 450.4 20.2 8.3e-135 450.1 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH48588.1 - 1.7e-23 83.2 30.5 1.7e-23 83.2 30.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily HECT PF00632.25 KFH48589.1 - 5e-75 252.8 0.0 6.9e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 4HBT PF03061.22 KFH48590.1 - 8e-13 48.5 0.1 1.3e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KFH48590.1 - 0.0018 17.6 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase MaoC_dehydratas PF01575.19 KFH48590.1 - 0.0019 17.8 0.1 0.004 16.7 0.1 1.5 1 1 0 1 1 1 1 MaoC like domain DUF4442 PF14539.6 KFH48590.1 - 0.0062 16.7 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) Glyco_hydro_15 PF00723.21 KFH48591.1 - 5.6e-93 312.2 0.0 8.4e-93 311.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KFH48591.1 - 1.8e-31 107.9 0.2 4e-31 106.8 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain adh_short_C2 PF13561.6 KFH48592.1 - 4.7e-70 235.8 1.1 5.3e-70 235.6 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFH48592.1 - 1.3e-52 178.1 1.2 1.5e-52 177.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFH48592.1 - 3.8e-14 53.0 0.7 6.5e-14 52.2 0.7 1.3 1 0 0 1 1 1 1 KR domain sCache_3_2 PF17203.4 KFH48592.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 Ribosomal_L3 PF00297.22 KFH48593.1 - 7.3e-185 614.2 9.8 8.3e-185 614.0 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2464 PF10240.9 KFH48593.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 Sulfotransfer_4 PF17784.1 KFH48594.1 - 1.3e-59 201.6 0.0 1.7e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFH48594.1 - 1.7e-05 25.3 1.1 0.002 18.5 0.0 3.0 1 1 1 3 3 3 2 Sulfotransferase family COX6B PF02297.17 KFH48595.1 - 7e-18 64.6 3.7 8.2e-18 64.4 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KFH48595.1 - 0.011 15.7 1.4 0.019 15.0 1.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KFH48595.1 - 0.06 13.3 1.6 0.061 13.3 0.8 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain Methyltransf_23 PF13489.6 KFH48596.1 - 5.7e-11 42.5 0.0 8.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH48596.1 - 2e-09 37.9 0.0 4.9e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH48596.1 - 1.1e-07 32.5 0.0 1.9e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH48596.1 - 8.1e-07 29.7 0.0 2.5e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH48596.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH48596.1 - 0.024 14.0 0.0 0.26 10.6 0.0 2.0 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CAP_GLY PF01302.25 KFH48597.1 - 2.2e-21 75.6 1.6 3.4e-21 75.0 1.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KFH48597.1 - 1.6e-20 73.3 0.0 3.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KFH48597.1 - 0.0003 20.5 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_2 PF00152.20 KFH48598.1 - 9e-76 254.9 0.2 1.3e-75 254.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFH48598.1 - 3.8e-09 36.4 0.0 9.2e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFH48598.1 - 2.5e-08 33.7 0.0 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF5492 PF17596.2 KFH48598.1 - 0.099 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5492) GDC-P PF02347.16 KFH48599.1 - 2.2e-159 530.9 0.1 8.2e-148 492.8 0.0 3.4 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFH48599.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFH48599.1 - 0.0088 14.6 0.0 0.14 10.6 0.0 2.1 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFH48599.1 - 0.051 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AP_endonuc_2 PF01261.24 KFH48600.1 - 2.8e-30 105.3 0.0 3.7e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FAR1 PF03101.15 KFH48601.1 - 0.00032 21.4 0.5 0.00032 21.4 0.5 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain CPSF100_C PF13299.6 KFH48601.1 - 0.022 14.9 4.3 0.039 14.1 4.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KFH48601.1 - 1.5 7.5 12.1 2.2 6.9 12.1 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KFH48601.1 - 1.9 8.2 3.5 3.3 7.4 3.5 1.5 1 0 0 1 1 1 0 Connexin DUF3043 PF11241.8 KFH48601.1 - 4 7.4 15.3 6.7 6.7 15.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SVIP PF15811.5 KFH48601.1 - 6.1 7.4 17.4 15 6.2 17.4 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Chorismate_bind PF00425.18 KFH48602.1 - 6.6e-91 304.4 0.0 2e-90 302.9 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KFH48602.1 - 1.5e-26 93.3 0.4 2.4e-22 79.7 0.0 3.9 4 1 0 4 4 4 2 Anthranilate synthase component I, N terminal region Pyr_redox_3 PF13738.6 KFH48603.1 - 1e-06 28.2 0.0 0.00012 21.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFH48603.1 - 9.2e-06 24.4 0.0 1.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFH48603.1 - 0.00017 20.9 0.0 0.00065 19.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFH48603.1 - 0.00031 20.9 0.0 0.0014 18.8 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH48603.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFH48603.1 - 0.05 13.2 0.4 12 5.4 0.1 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thioredoxin_7 PF13899.6 KFH48604.1 - 2.4e-14 53.3 0.0 5.1e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KFH48604.1 - 9.8e-11 41.3 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFH48604.1 - 1.7e-07 31.4 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Ribosomal_60s PF00428.19 KFH48604.1 - 2.1 9.0 11.4 4.8 7.8 2.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C48 PF02902.19 KFH48605.1 - 5.6e-21 75.4 0.0 1e-20 74.5 0.0 1.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HPP PF04982.13 KFH48606.1 - 2.8e-41 140.5 6.7 4.5e-41 139.9 6.7 1.3 1 0 0 1 1 1 1 HPP family OPT PF03169.15 KFH48606.1 - 0.011 14.4 1.2 0.019 13.6 1.2 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4126 PF13548.6 KFH48606.1 - 0.4 10.3 12.1 0.74 9.5 12.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4126) AMP-binding PF00501.28 KFH48607.1 - 3.7e-267 885.7 0.0 6.9e-91 304.9 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFH48607.1 - 3.7e-246 817.1 0.1 1e-89 301.3 0.2 5.1 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.25 KFH48607.1 - 1.6e-44 150.1 0.3 2.1e-14 53.6 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFH48607.1 - 7.5e-27 94.1 0.0 1e-08 36.1 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 KFH48607.1 - 1.6e-26 93.8 0.0 5e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFH48607.1 - 0.00056 20.6 0.1 0.0056 17.3 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family AATase PF07247.12 KFH48607.1 - 0.0018 16.9 0.1 0.93 8.0 0.0 2.5 2 0 0 2 2 2 2 Alcohol acetyltransferase Abhydrolase_1 PF00561.20 KFH48607.1 - 0.11 12.1 0.0 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold CitT PF12431.8 KFH48607.1 - 0.28 11.6 1.1 55 4.3 0.0 3.6 3 0 0 3 3 3 0 Transcriptional regulator Zn_clus PF00172.18 KFH48608.1 - 4e-08 33.2 9.0 6.8e-08 32.5 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH48608.1 - 5.7e-07 28.7 1.3 9.1e-07 28.0 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF726 PF05277.12 KFH48609.1 - 1.3e-96 323.5 0.0 1.8e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SIP1 PF04938.12 KFH48609.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Cyclase PF04199.13 KFH48610.1 - 7.9e-16 58.5 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase NAD_binding_10 PF13460.6 KFH48611.1 - 1.1e-22 80.8 0.2 1.5e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH48611.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFH48611.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TFIIA PF03153.13 KFH48612.1 - 0.0018 18.4 28.0 0.0031 17.6 28.0 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KFH48612.1 - 0.73 9.1 23.0 0.15 11.4 14.3 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KFH48612.1 - 6.2 4.9 22.7 10 4.2 22.7 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.18 KFH48613.1 - 5.2e-19 68.3 0.1 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48613.1 - 1.4e-05 25.1 9.3 2.4e-05 24.4 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.12 KFH48613.1 - 0.089 13.4 2.1 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Striatin family DUF1373 PF07117.11 KFH48613.1 - 0.15 12.0 6.5 0.27 11.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) SUIM_assoc PF16619.5 KFH48613.1 - 5.7 7.1 11.6 0.95 9.6 1.5 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 KFH48614.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoVAD PF07451.11 KFH48614.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF1343 PF07075.11 KFH48615.1 - 5.3e-110 368.1 0.0 6.2e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) SinI PF08671.10 KFH48615.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI S10_plectin PF03501.15 KFH48616.1 - 5.4e-43 145.0 0.1 6.6e-43 144.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain COG5 PF10392.9 KFH48617.1 - 0.0026 17.9 2.6 0.038 14.2 0.4 3.4 3 1 0 3 3 3 1 Golgi transport complex subunit 5 DUF4795 PF16043.5 KFH48617.1 - 0.018 14.6 1.2 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF812 PF05667.11 KFH48617.1 - 0.023 13.6 3.7 0.034 13.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4142 PF13628.6 KFH48617.1 - 0.051 13.8 4.3 0.45 10.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4142) HSBP1 PF06825.12 KFH48617.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF2040 PF09745.9 KFH48617.1 - 0.16 12.0 2.3 2 8.5 0.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) DUF445 PF04286.12 KFH48617.1 - 1.2 8.8 4.4 1.8 8.3 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) UVR PF02151.19 KFH48617.1 - 1.3 8.8 5.1 2.9 7.7 2.5 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif Homeobox_KN PF05920.11 KFH48618.1 - 1.4e-15 56.9 1.5 3.4e-15 55.6 1.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KFH48618.1 - 8.8e-14 51.3 5.1 6.3e-06 26.1 0.1 5.2 5 1 0 5 5 5 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KFH48618.1 - 8.4e-05 22.3 0.2 8.4e-05 22.3 0.2 2.3 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KFH48618.1 - 0.0035 18.1 3.8 0.0035 18.1 3.8 4.8 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFH48618.1 - 0.21 12.1 20.5 0.044 14.3 3.9 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 KFH48618.1 - 0.53 9.9 4.3 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_clus PF00172.18 KFH48618.1 - 0.94 9.7 3.3 5.1 7.3 3.3 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KFH48618.1 - 0.99 9.5 3.3 4.2 7.5 3.1 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF974 PF06159.13 KFH48619.1 - 2.9e-80 269.6 0.0 3.5e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) B12D PF06522.11 KFH48620.1 - 0.00081 19.1 0.2 0.0013 18.5 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Citrate_bind PF16114.5 KFH48621.1 - 5.2e-87 289.9 0.0 7.1e-87 289.5 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KFH48621.1 - 1.9e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KFH48621.1 - 0.038 12.1 0.0 0.053 11.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) SPRY PF00622.28 KFH48622.1 - 0.00014 22.0 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 SPRY domain KH_1 PF00013.29 KFH48623.1 - 1.5e-10 40.7 0.1 8e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 KH domain SbcD_C PF12320.8 KFH48623.1 - 0.07 13.4 0.1 13 6.1 0.1 2.3 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain DUF4410 PF14366.6 KFH48623.1 - 0.12 12.2 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Fungal_trans_2 PF11951.8 KFH48624.1 - 4e-06 25.9 2.7 1.1e-05 24.4 2.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFH48625.1 - 2.7e-35 121.9 38.7 8.6e-21 74.2 4.0 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48625.1 - 0.00016 20.6 15.8 0.0063 15.4 4.6 3.5 3 1 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.13 KFH48626.1 - 2.4e-69 234.3 23.4 3.1e-69 234.0 23.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFH48626.1 - 4.8e-20 71.8 60.0 4.4e-18 65.3 57.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily NuiA PF07924.11 KFH48627.1 - 0.0015 18.9 0.0 0.092 13.1 0.0 2.2 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein LKAAEAR PF15478.6 KFH48627.1 - 0.039 14.2 0.0 0.083 13.2 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif DJ-1_PfpI PF01965.24 KFH48628.1 - 3.7e-13 49.6 0.0 6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFH48628.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 KFH48628.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Sugar_tr PF00083.24 KFH48629.1 - 4.8e-97 325.7 14.6 5.6e-97 325.4 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH48629.1 - 4.5e-20 71.9 34.6 1.3e-13 50.6 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.8 KFH48630.1 - 1.8e-12 47.3 3.5 6.5e-11 42.3 3.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) OTCace_N PF02729.21 KFH48631.1 - 1.3e-43 148.6 0.0 1.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFH48631.1 - 7.8e-43 146.3 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain RRM_1 PF00076.22 KFH48632.1 - 1.5e-47 159.3 0.0 1.4e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH48632.1 - 9.5e-07 28.7 0.3 0.0023 17.9 0.1 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFH48632.1 - 3.7e-05 23.5 0.0 0.051 13.4 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFH48632.1 - 9.1e-05 22.4 0.0 0.0018 18.3 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KFH48632.1 - 0.00028 20.9 0.0 0.054 13.6 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KFH48632.1 - 0.024 14.2 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ING PF12998.7 KFH48633.1 - 5.2e-07 30.2 0.3 0.004 17.7 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFH48633.1 - 2.1e-06 27.5 8.0 3.6e-06 26.8 8.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFH48633.1 - 0.37 11.1 1.9 0.85 9.9 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain SOR_SNZ PF01680.17 KFH48634.1 - 6.1e-103 343.0 7.0 8.4e-103 342.5 7.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KFH48634.1 - 7.1e-11 41.9 4.9 5.1e-07 29.3 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFH48634.1 - 1.5e-05 24.3 0.9 0.1 11.6 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 KFH48634.1 - 0.00078 18.7 0.3 0.013 14.7 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 KFH48634.1 - 0.0028 17.7 0.0 0.0083 16.2 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 KFH48634.1 - 0.0073 15.8 0.4 0.088 12.3 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein DUF4398 PF14346.6 KFH48634.1 - 0.0085 16.7 1.0 0.03 14.9 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) NanE PF04131.14 KFH48634.1 - 0.011 14.9 1.5 0.15 11.2 0.0 2.8 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KFH48634.1 - 0.079 12.3 1.8 0.54 9.6 0.1 2.6 2 2 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 KFH48634.1 - 0.92 8.8 9.6 0.68 9.3 2.5 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Hamartin PF04388.12 KFH48635.1 - 1.3e-15 57.1 45.3 5.7e-14 51.7 40.3 4.5 1 1 1 2 2 2 1 Hamartin protein Sec7_N PF12783.7 KFH48635.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Macoilin PF09726.9 KFH48635.1 - 0.39 9.2 41.0 0.38 9.3 39.1 1.6 1 1 1 2 2 2 0 Macoilin family GATase PF00117.28 KFH48636.1 - 4.5e-47 160.3 0.0 6.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KFH48636.1 - 6.2e-46 155.4 0.0 1.2e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KFH48636.1 - 1.9e-05 24.5 0.2 0.0018 18.1 0.1 2.3 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.24 KFH48636.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glyco_transf_20 PF00982.21 KFH48637.1 - 9.4e-164 545.6 0.1 1.3e-163 545.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFH48637.1 - 6.7e-45 153.0 0.0 1e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KFH48637.1 - 0.078 12.7 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Choline_kinase PF01633.20 KFH48638.1 - 6.4e-61 205.6 0.0 1.3e-60 204.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KFH48638.1 - 1.6e-18 66.1 0.0 3.1e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KFH48638.1 - 4.5e-05 23.5 0.2 4.5e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Reprolysin_5 PF13688.6 KFH48639.1 - 7e-57 192.8 1.5 7e-57 192.8 1.5 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFH48639.1 - 3e-49 167.6 0.3 7.6e-49 166.3 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFH48639.1 - 1.7e-43 148.6 0.1 2.9e-43 147.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFH48639.1 - 1.2e-16 61.2 35.4 1.2e-16 61.2 35.4 4.7 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFH48639.1 - 1.9e-09 38.1 0.0 7.8e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFH48639.1 - 4.6e-06 26.7 3.8 0.00011 22.1 3.8 2.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFH48639.1 - 0.00014 22.4 10.6 0.00014 22.4 10.6 5.0 2 1 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KFH48639.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide RRM_1 PF00076.22 KFH48640.1 - 6.6e-20 70.7 0.0 9.7e-20 70.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH48640.1 - 3.5e-06 27.1 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFH48640.1 - 0.00048 20.1 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KFH48640.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFH48640.1 - 0.0037 16.8 0.0 0.0074 15.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFH48640.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KFH48640.1 - 0.17 11.8 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif DUF3237 PF11578.8 KFH48641.1 - 3.1e-23 82.2 0.0 4.4e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OST-HTH PF12872.7 KFH48641.1 - 0.23 11.3 0.0 0.43 10.4 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Mucin PF01456.17 KFH48641.1 - 3.1 7.8 18.9 6.5 6.8 18.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pam17 PF08566.10 KFH48642.1 - 4.3e-62 208.8 0.0 6.1e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 V_ATPase_I PF01496.19 KFH48643.1 - 3.2e-299 994.5 0.0 3.6e-299 994.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YojJ PF10372.9 KFH48643.1 - 0.018 15.1 0.4 10 6.3 0.0 3.0 3 0 0 3 3 2 0 Bacterial membrane-spanning protein N-terminus CheZ PF04344.13 KFH48643.1 - 0.022 14.7 2.0 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ MAD PF05557.13 KFH48643.1 - 0.054 11.9 2.2 0.63 8.3 0.4 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Tnp_22_trimer PF17489.2 KFH48643.1 - 0.054 13.5 1.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 L1 transposable element trimerization domain Golgin_A5 PF09787.9 KFH48643.1 - 0.11 11.9 4.5 1.5 8.2 0.7 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3552 PF12072.8 KFH48643.1 - 0.2 11.1 3.5 8.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) EzrA PF06160.12 KFH48643.1 - 0.22 9.6 4.2 1.6 6.8 0.3 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4763 PF15960.5 KFH48643.1 - 0.23 10.8 0.8 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 KFH48643.1 - 0.24 10.2 2.3 4.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein PspB PF06667.12 KFH48643.1 - 0.32 11.1 2.3 1.3 9.2 0.2 2.9 3 0 0 3 3 3 0 Phage shock protein B UPF0449 PF15136.6 KFH48643.1 - 0.42 11.1 2.9 16 6.1 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Prefoldin_2 PF01920.20 KFH48643.1 - 0.43 10.6 2.6 5.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit CorA PF01544.18 KFH48643.1 - 0.44 9.8 3.2 8 5.7 0.4 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Fmp27_WPPW PF10359.9 KFH48643.1 - 0.57 9.0 2.3 2.1 7.1 0.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4140 PF13600.6 KFH48643.1 - 0.68 10.4 4.4 1.2 9.6 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1515 PF07439.11 KFH48643.1 - 0.83 9.7 0.0 0.83 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 KFH48643.1 - 1.3 9.1 4.9 1.9 8.5 0.3 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KFH48643.1 - 1.8 7.8 5.1 1.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KFH48643.1 - 2.1 8.8 5.3 7.7 7.0 0.5 2.6 2 0 0 2 2 2 0 Cell division protein ZapB SCO1-SenC PF02630.14 KFH48644.1 - 1.2e-48 164.4 0.0 1.6e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFH48644.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFH48644.1 - 0.042 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KFH48644.1 - 0.064 13.0 0.0 0.38 10.5 0.0 2.0 1 1 0 1 1 1 0 Redoxin MFS_1 PF07690.16 KFH48645.1 - 8.5e-46 156.5 38.7 8.5e-46 156.5 38.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48645.1 - 9.5e-13 47.8 9.9 9.5e-13 47.8 9.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KFH48645.1 - 0.0016 16.9 14.0 0.0041 15.6 4.0 2.2 1 1 1 2 2 2 2 Transmembrane secretion effector PI-PLC-X PF00388.19 KFH48646.1 - 2.7e-43 147.0 0.0 4.5e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFH48646.1 - 6.6e-38 129.6 0.0 9.7e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFH48646.1 - 0.00015 22.0 0.0 0.00037 20.7 0.0 1.7 1 1 0 1 1 1 1 C2 domain DNA_pol3_delta2 PF13177.6 KFH48649.1 - 9.8e-11 41.7 0.1 2.2e-10 40.6 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KFH48649.1 - 9e-07 29.2 0.1 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFH48649.1 - 3.3e-06 27.6 0.1 7.1e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH48649.1 - 0.00013 22.4 0.3 0.0015 18.9 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 KFH48649.1 - 0.00075 19.9 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 KFH48649.1 - 0.001 18.8 0.2 0.0027 17.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFH48649.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KFH48649.1 - 0.022 15.2 0.0 0.065 13.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.13 KFH48649.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit T4SS-DNA_transf PF02534.14 KFH48649.1 - 0.079 11.7 0.1 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Mob1_phocein PF03637.17 KFH48650.1 - 1.4e-69 233.5 0.0 1.8e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ank_2 PF12796.7 KFH48651.1 - 1.4e-42 144.1 0.3 1.2e-12 48.2 0.0 5.8 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFH48651.1 - 1.4e-30 105.3 0.1 2.6e-06 27.9 0.0 7.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH48651.1 - 3.7e-27 91.4 1.2 0.0024 18.2 0.0 10.3 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KFH48651.1 - 3e-23 81.6 4.7 2.9e-05 24.2 0.0 7.8 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KFH48651.1 - 3.4e-19 68.4 7.4 0.0017 18.7 0.0 8.4 9 1 0 9 9 9 4 Ankyrin repeat Phage_T7_Capsid PF05396.11 KFH48651.1 - 0.027 14.8 0.0 11 6.4 0.0 3.9 3 1 1 4 4 4 0 Phage T7 capsid assembly protein DLH PF01738.18 KFH48653.1 - 1.1e-24 87.2 0.0 2.3e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KFH48653.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal OSCP PF00213.18 KFH48655.1 - 8.8e-46 156.2 0.9 1e-45 155.9 0.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit SRA1 PF07304.11 KFH48656.1 - 2.4e-12 46.8 0.0 2.4e-12 46.8 0.0 3.9 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KFH48656.1 - 3.2e-11 43.4 0.2 6.1e-10 39.2 0.1 2.7 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFH48656.1 - 1.7e-07 31.8 0.5 0.22 12.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Prp18 PF02840.15 KFH48656.1 - 0.052 13.6 1.9 0.07 13.2 0.3 2.0 2 1 0 2 2 2 0 Prp18 domain SLX9 PF15341.6 KFH48657.1 - 1.3e-33 116.2 4.1 1.8e-33 115.7 4.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 V_ATPase_I PF01496.19 KFH48657.1 - 0.016 13.2 0.2 0.018 13.0 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S28 PF05577.12 KFH48658.1 - 1.8e-52 178.6 0.0 1e-51 176.2 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 p450 PF00067.22 KFH48659.1 - 2.5e-86 290.3 0.0 3e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VARLMGL PF14383.6 KFH48659.1 - 0.24 11.0 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 DUF761-associated sequence motif RRM_1 PF00076.22 KFH48660.1 - 1.4e-08 34.5 0.1 8.2e-06 25.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFH48660.1 - 4.4e-08 33.0 0.0 0.00027 20.8 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 KFH48660.1 - 3.6e-06 27.2 0.0 7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFH48660.1 - 0.0014 18.5 5.4 0.0027 17.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 KFH48660.1 - 0.0028 17.5 0.0 0.2 11.5 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif Transcrip_act PF04949.13 KFH48660.1 - 0.068 13.1 7.4 0.12 12.3 7.4 1.3 1 0 0 1 1 1 0 Transcriptional activator Ribosomal_60s PF00428.19 KFH48660.1 - 0.068 13.8 0.1 0.29 11.7 0.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spc7 PF08317.11 KFH48660.1 - 0.07 12.0 11.2 0.11 11.4 11.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf_CCCH_4 PF18345.1 KFH48660.1 - 0.072 13.2 4.2 0.14 12.2 4.2 1.5 1 0 0 1 1 1 0 Zinc finger domain Atg14 PF10186.9 KFH48660.1 - 0.093 11.8 5.1 0.13 11.3 5.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PHM7_cyt PF14703.6 KFH48660.1 - 1.2 9.3 7.4 0.65 10.2 0.1 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Exonuc_VII_L PF02601.15 KFH48660.1 - 1.5 8.4 5.9 2.2 7.8 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 KFH48660.1 - 3.5 6.0 10.8 5.1 5.5 10.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein UPF0242 PF06785.11 KFH48660.1 - 4.1 7.5 10.6 6.5 6.8 10.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KFH48660.1 - 4.7 7.5 16.1 8.3 6.7 16.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KFH48660.1 - 9.3 5.5 12.5 14 4.9 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RFC1 PF08519.12 KFH48661.1 - 1.9e-58 197.1 0.0 1e-57 194.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFH48661.1 - 4.5e-15 55.8 0.0 1.2e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFH48661.1 - 8.6e-10 39.2 0.0 6.2e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFH48661.1 - 7.6e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFH48661.1 - 0.0049 17.3 0.0 0.028 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFH48661.1 - 0.0069 16.9 0.2 0.038 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFH48661.1 - 0.0088 16.3 0.0 0.1 12.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFH48661.1 - 0.025 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFH48661.1 - 0.035 13.9 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KFH48661.1 - 0.059 13.3 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KFH48661.1 - 0.063 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KFH48661.1 - 0.089 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFH48661.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFH48661.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PTCB-BRCT PF12738.7 KFH48661.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_28 PF13521.6 KFH48661.1 - 0.29 11.4 2.8 0.75 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Hydrolase_6 PF13344.6 KFH48662.1 - 4.6e-16 58.8 0.0 9.8e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH48662.1 - 1.1e-15 57.4 0.0 2.9e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like FYVE_2 PF02318.16 KFH48664.1 - 0.16 12.2 16.4 0.65 10.2 2.6 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger Prenyltransf PF01255.19 KFH48665.1 - 1.5e-80 270.0 0.0 2.2e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase C2 PF00168.30 KFH48666.1 - 3.5e-09 36.9 0.0 6.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain TRAPPC10 PF12584.8 KFH48667.1 - 2.1e-25 89.3 0.0 4.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF2057 PF09829.9 KFH48667.1 - 0.027 14.6 0.0 0.09 12.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) MutS_V PF00488.21 KFH48668.1 - 4.1e-63 212.8 0.4 9.1e-63 211.7 0.4 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFH48668.1 - 7.3e-29 101.4 1.2 2e-28 99.9 1.2 1.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KFH48668.1 - 1.1e-07 32.3 0.0 4.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFH48668.1 - 3.6e-07 30.4 0.1 9.1e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV Mak10 PF04112.13 KFH48669.1 - 1.2e-60 203.8 0.0 4.5e-60 202.0 0.0 1.9 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CHCH PF06747.13 KFH48670.1 - 3.2e-07 30.3 16.1 8e-06 25.8 5.6 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KFH48670.1 - 7.8e-06 25.8 8.0 0.00078 19.4 3.6 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KFH48670.1 - 0.14 12.5 9.1 1.1 9.6 1.4 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KFH48670.1 - 0.42 10.7 10.1 0.19 11.7 0.8 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4381 PF14316.6 KFH48671.1 - 0.04 14.2 1.1 0.059 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 KFH48671.1 - 0.24 11.2 0.4 0.38 10.6 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RPN6_N PF18055.1 KFH48672.1 - 5.2e-41 139.7 4.7 5.9e-41 139.5 2.6 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KFH48672.1 - 3.8e-21 75.6 0.1 1.5e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KFH48672.1 - 1.4e-10 40.7 0.5 1.4e-10 40.7 0.5 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KFH48672.1 - 0.00012 21.8 0.2 0.00012 21.8 0.2 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_12 PF13424.6 KFH48672.1 - 0.0018 18.6 17.9 0.18 12.1 0.7 5.1 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFH48672.1 - 0.0021 17.5 1.7 0.0021 17.5 1.7 2.5 2 2 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KFH48672.1 - 0.0086 16.0 1.0 12 6.2 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KFH48672.1 - 0.012 15.6 0.1 0.083 12.9 0.0 2.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KFH48672.1 - 0.036 14.2 0.1 0.27 11.4 0.0 2.4 3 0 0 3 3 3 0 DprA winged helix domain DASH_Dad1 PF08649.10 KFH48673.1 - 8e-28 96.4 1.8 9.7e-28 96.1 1.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KFH48673.1 - 0.012 15.6 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 SART-1 PF03343.13 KFH48675.1 - 3.1e-187 624.0 58.0 3.6e-187 623.8 58.0 1.0 1 0 0 1 1 1 1 SART-1 family AHSA1 PF08327.11 KFH48676.1 - 0.029 14.6 0.1 0.054 13.7 0.1 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Fimbrial_PilY2 PF14481.6 KFH48676.1 - 0.11 12.1 0.8 3.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Type 4 fimbrial biogenesis protein PilY2 ALGX PF16822.5 KFH48677.1 - 0.027 14.2 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Peptidase_M20 PF01546.28 KFH48678.1 - 6.7e-23 81.5 1.7 2.9e-21 76.1 1.7 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFH48678.1 - 1.2e-19 70.2 0.0 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFH48678.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KFH48678.1 - 0.066 12.2 0.2 0.43 9.5 0.1 2.0 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase MFS_1 PF07690.16 KFH48679.1 - 1.1e-49 169.3 40.8 5.5e-49 167.0 41.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH48679.1 - 4.6e-13 48.5 16.9 6.4e-13 48.0 16.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH48679.1 - 2.2e-11 43.3 9.6 2.2e-11 43.3 9.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KFH48679.1 - 0.00021 20.7 5.7 0.00021 20.7 5.7 2.3 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KFH48679.1 - 1.2 7.4 16.9 0.11 10.7 3.4 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Mito_carr PF00153.27 KFH48680.1 - 7.7e-48 160.4 4.6 1.1e-16 60.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 KFH48680.1 - 0.033 14.1 1.1 0.075 13.0 0.3 2.1 2 1 0 2 2 2 0 UcrQ family Wzz PF02706.15 KFH48680.1 - 0.17 12.2 0.5 1.1 9.6 0.1 2.4 3 0 0 3 3 3 0 Chain length determinant protein Skp1_POZ PF03931.15 KFH48681.1 - 1.6e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Mpv17_PMP22 PF04117.12 KFH48682.1 - 8.8e-11 41.9 6.3 2.3e-10 40.5 6.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family FMO-like PF00743.19 KFH48684.1 - 3.5e-16 58.7 0.0 8.4e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFH48684.1 - 3.2e-11 43.0 0.0 5.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFH48684.1 - 4.6e-11 43.0 0.3 6.3e-10 39.3 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFH48684.1 - 2.9e-09 37.0 0.2 2.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFH48684.1 - 7.1e-07 28.7 0.1 4.1e-05 22.9 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFH48684.1 - 0.00018 20.9 0.0 0.25 10.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH48684.1 - 0.00038 20.1 0.0 0.062 12.9 0.0 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFH48684.1 - 0.005 16.1 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KFH48684.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KFH48684.1 - 0.025 15.2 0.2 8.3 7.1 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFH48684.1 - 0.038 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GET2 PF08690.10 KFH48685.1 - 3.1e-53 181.5 0.0 3.8e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Pkinase PF00069.25 KFH48687.1 - 4.4e-55 186.9 0.2 1.6e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48687.1 - 7.6e-37 127.0 0.0 1.9e-36 125.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48687.1 - 3.8e-06 26.4 0.0 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFH48687.1 - 0.02 14.8 3.1 0.042 13.8 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFH48687.1 - 0.32 9.7 1.5 0.47 9.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF3896 PF13035.6 KFH48687.1 - 0.43 10.8 0.1 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) FAM76 PF16046.5 KFH48687.1 - 1.4 8.2 4.6 1.1 8.6 2.2 1.9 2 0 0 2 2 2 0 FAM76 protein Fungal_trans PF04082.18 KFH48688.1 - 2.6e-16 59.5 0.3 4.5e-16 58.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48688.1 - 3.4e-07 30.3 13.4 6e-07 29.5 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RILP PF11461.8 KFH48688.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Rab interacting lysosomal protein CCD48 PF15799.5 KFH48688.1 - 0.034 12.5 0.7 0.058 11.7 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Ndc1_Nup PF09531.10 KFH48688.1 - 0.04 12.6 0.3 0.072 11.8 0.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aldo_ket_red PF00248.21 KFH48689.1 - 1.2e-16 60.7 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KFH48690.1 - 3.6e-39 134.7 33.9 5.7e-39 134.0 33.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFH48690.1 - 3.6e-15 55.8 18.1 9.7e-15 54.4 18.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFH48690.1 - 3.6e-06 25.7 1.8 3.6e-06 25.7 1.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4112 PF13430.6 KFH48690.1 - 0.15 12.3 1.7 0.36 11.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) COX14 PF14880.6 KFH48690.1 - 0.93 9.4 0.0 0.93 9.4 0.0 2.9 4 0 0 4 4 4 0 Cytochrome oxidase c assembly PPI_Ypi1 PF07491.11 KFH48691.1 - 5.7e-25 86.9 0.5 2.3e-24 85.0 0.5 2.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.9 KFH48691.1 - 1.5 8.3 18.4 2.7 7.5 18.4 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Syntaphilin PF15290.6 KFH48691.1 - 6.1 6.4 11.1 0.8 9.3 7.1 1.5 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp SMC_Nse1 PF07574.13 KFH48692.1 - 5.1e-64 215.8 0.1 6.4e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFH48692.1 - 2.1e-13 50.3 5.1 3.1e-13 49.8 5.1 1.3 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFH48692.1 - 0.016 15.5 3.3 0.017 15.4 0.5 2.1 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 KFH48692.1 - 0.24 11.7 1.7 0.45 10.8 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 KFH48692.1 - 0.71 9.8 5.0 1.2 9.1 5.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SNO PF01174.19 KFH48693.1 - 5.4e-57 192.7 0.0 1.5e-55 188.0 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFH48693.1 - 1.1e-09 38.2 0.0 1.8e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KFH48693.1 - 2e-05 24.4 0.0 0.00021 21.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KFH48693.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KFH48693.1 - 0.0045 16.7 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S51 GATase_5 PF13507.6 KFH48693.1 - 0.011 14.8 0.1 0.58 9.2 0.0 2.3 2 1 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 KFH48693.1 - 0.093 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like TAF4 PF05236.14 KFH48694.1 - 1.6e-30 106.8 0.2 4.9e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.32 KFH48695.1 - 7.3e-07 29.8 11.0 0.15 13.0 0.0 6.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48695.1 - 0.00016 21.9 0.3 2.2 8.6 0.0 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH48695.1 - 0.028 14.3 0.0 13 5.6 0.0 3.2 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A MMR_HSR1 PF01926.23 KFH48696.1 - 3.5e-05 23.9 0.0 0.31 11.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Oxidored_FMN PF00724.20 KFH48698.1 - 3.4e-55 187.7 0.0 4.4e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AIG2_2 PF13772.6 KFH48699.1 - 0.0072 16.7 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family DS PF01916.17 KFH48700.1 - 2.3e-132 440.6 0.0 2.7e-132 440.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Pkinase PF00069.25 KFH48701.1 - 2.4e-69 233.7 0.0 3.4e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48701.1 - 8.9e-51 172.6 0.0 1.5e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFH48701.1 - 8.2e-05 21.5 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFH48701.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KFH48701.1 - 0.27 10.1 0.0 5.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Aminotran_4 PF01063.19 KFH48702.1 - 1.3e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Cas1_AcylT PF07779.12 KFH48703.1 - 8.3e-53 180.0 0.0 1.6e-52 179.0 0.0 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p WD40 PF00400.32 KFH48704.1 - 2.4e-17 63.0 9.2 0.00029 21.5 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48704.1 - 1.2e-05 25.6 0.1 0.18 12.1 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 KFH48705.1 - 8e-47 155.2 33.9 5.5e-08 32.3 0.1 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFH48705.1 - 5.6e-42 138.5 23.6 1.9e-05 24.4 0.0 10.2 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48705.1 - 7.2e-29 97.6 19.5 0.00081 19.4 0.6 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 KFH48705.1 - 1.3e-27 96.1 12.3 3e-06 27.8 0.1 7.0 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFH48705.1 - 1.8e-24 84.3 22.3 0.0024 18.1 0.1 9.1 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFH48705.1 - 7e-24 84.1 16.5 5.4e-06 26.8 0.2 6.9 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFH48705.1 - 2.9e-22 77.4 10.8 0.0083 16.9 0.1 9.0 3 2 6 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFH48705.1 - 1.3e-20 72.8 29.8 3.5e-06 26.6 0.2 9.1 5 2 4 9 9 9 5 TPR repeat TPR_6 PF13174.6 KFH48705.1 - 1.6e-18 66.0 15.6 0.014 16.0 0.6 10.0 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFH48705.1 - 6.2e-17 61.7 25.1 3.6e-05 24.0 1.0 7.4 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KFH48705.1 - 1.1e-14 53.2 13.6 0.0096 15.9 0.1 9.2 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFH48705.1 - 3.3e-14 52.8 9.7 0.00081 19.5 0.1 6.1 3 2 2 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH48705.1 - 1.4e-10 41.2 9.7 6.1e-08 32.8 2.5 3.0 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFH48705.1 - 1e-09 38.0 9.3 0.0014 17.9 3.6 5.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 KFH48705.1 - 1.1e-05 25.2 9.5 0.47 10.1 0.0 4.9 3 2 0 4 4 4 3 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KFH48705.1 - 0.0001 22.3 0.1 1.1 9.3 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KFH48705.1 - 0.0015 18.8 0.5 3.1 8.2 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 KFH48705.1 - 0.011 15.5 4.4 0.23 11.2 0.2 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 KFH48705.1 - 0.038 13.0 0.1 7.9 5.4 0.0 2.4 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KFH48705.1 - 0.11 12.4 14.9 3.6 7.6 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.17 KFH48705.1 - 0.14 12.6 12.1 4.3 7.8 0.1 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain SNAP PF14938.6 KFH48705.1 - 0.86 9.0 15.8 5 6.5 3.7 4.3 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 KFH48705.1 - 1.4 9.1 21.2 9.5 6.4 0.4 6.4 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 KFH48705.1 - 7.2 6.3 5.9 50 3.5 0.0 4.2 4 2 0 4 4 4 0 26S proteasome subunit RPN7 MFS_1 PF07690.16 KFH48706.1 - 3.5e-43 147.9 32.0 3.5e-43 147.9 32.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFH48706.1 - 9.4e-10 37.5 1.9 1.4e-09 37.0 1.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFH48706.1 - 3.8e-07 29.4 22.3 1.5e-06 27.4 22.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.9 KFH48706.1 - 0.0097 16.1 9.1 0.03 14.5 0.9 3.2 3 0 0 3 3 3 2 Predicted membrane protein (DUF2178) Methyltransf_25 PF13649.6 KFH48707.1 - 4.8e-11 43.2 0.0 8.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH48707.1 - 1e-10 42.1 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH48707.1 - 5.2e-07 29.6 0.0 8.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH48707.1 - 1.9e-05 25.3 0.0 3.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH48707.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF3446 PF11928.8 KFH48707.1 - 6.8 7.1 8.4 15 6.0 4.5 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain K_oxygenase PF13434.6 KFH48709.1 - 1.6e-14 53.8 0.0 4.7e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFH48709.1 - 2e-07 30.6 0.0 0.018 14.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH48709.1 - 7e-07 28.8 0.0 0.017 14.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH48709.1 - 5.2e-05 23.0 6.5 0.12 12.0 2.5 3.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFH48709.1 - 5.7e-05 22.5 0.1 0.0089 15.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFH48709.1 - 0.00071 19.8 0.3 0.015 15.6 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFH48709.1 - 0.0032 16.8 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFH48709.1 - 0.011 15.7 0.1 0.47 10.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFH48709.1 - 0.021 13.6 0.0 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KFH48709.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFH48709.1 - 0.084 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HRI1 PF16815.5 KFH48710.1 - 1.1e-74 251.0 0.7 1.3e-74 250.8 0.7 1.0 1 0 0 1 1 1 1 Protein HRI1 WD40 PF00400.32 KFH48711.1 - 1e-57 190.7 35.4 1.2e-10 41.7 0.5 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48711.1 - 8e-24 83.8 6.6 5e-05 23.5 0.1 6.5 3 3 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH48711.1 - 2e-07 31.1 0.3 0.00078 19.4 0.0 3.7 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFH48711.1 - 6.3e-07 28.7 0.2 0.8 8.6 0.0 5.1 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFH48711.1 - 1e-05 25.3 0.9 0.31 11.0 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFH48711.1 - 1.7e-05 23.7 2.9 5.2 5.6 0.1 5.3 4 2 2 6 6 6 2 Nucleoporin Nup120/160 NLE PF08154.12 KFH48711.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Proteasome_A_N PF10584.9 KFH48711.1 - 0.014 15.1 0.0 14 5.5 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KFH48711.1 - 0.029 13.7 0.0 29 3.8 0.0 3.7 4 0 0 4 4 4 0 WD40-like domain ASH PF15780.5 KFH48711.1 - 0.03 14.5 0.2 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AMP-binding PF00501.28 KFH48713.1 - 5.7e-64 216.3 0.0 7.5e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH48713.1 - 1.1e-06 29.5 0.0 2.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sde2_N_Ubi PF13019.6 KFH48714.1 - 2.8e-70 235.4 0.6 3.7e-70 235.0 0.6 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 KFH48714.1 - 0.016 15.7 2.5 3 8.5 2.3 2.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain His_Phos_1 PF00300.22 KFH48714.1 - 0.067 12.9 2.1 0.095 12.4 2.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) P16-Arc PF04699.14 KFH48717.1 - 1.3e-51 175.0 0.0 1.5e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Fungal_trans PF04082.18 KFH48718.1 - 8.4e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48718.1 - 1.4e-05 25.1 9.9 2.5e-05 24.3 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain L51_S25_CI-B8 PF05047.16 KFH48719.1 - 5.1e-18 64.7 0.2 8.5e-18 64.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Coatomer_b_Cpla PF14806.6 KFH48719.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.2 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform RSN1_7TM PF02714.15 KFH48720.1 - 5e-72 242.5 29.5 5e-72 242.5 29.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFH48720.1 - 6.6e-38 129.9 0.9 6.6e-38 129.9 0.9 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFH48720.1 - 3.9e-36 124.9 0.0 5.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Glyco_hydro_cc PF11790.8 KFH48721.1 - 4.5e-56 190.1 1.8 5.6e-56 189.8 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ala_racemase_N PF01168.20 KFH48723.1 - 1.9e-20 73.5 0.0 2.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-RING_2 PF13639.6 KFH48724.1 - 2.5e-12 46.9 4.3 4.9e-12 46.0 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFH48724.1 - 1.5e-10 40.6 0.9 3e-10 39.6 0.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFH48724.1 - 2.4e-07 30.5 4.0 3.9e-07 29.8 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFH48724.1 - 7.5e-07 28.9 3.6 1.2e-06 28.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFH48724.1 - 1.2e-05 25.5 5.0 2.8e-05 24.3 5.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFH48724.1 - 5.4e-05 23.1 1.8 9.3e-05 22.3 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFH48724.1 - 0.0003 20.6 4.3 0.00055 19.7 4.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFH48724.1 - 0.0013 18.6 2.2 0.0022 17.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH48724.1 - 0.014 15.4 3.0 0.032 14.2 2.9 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFH48724.1 - 0.021 14.9 0.8 0.043 13.9 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFH48724.1 - 0.3 10.9 3.4 0.61 9.9 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KFH48724.1 - 0.41 10.7 4.9 0.85 9.7 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KFH48724.1 - 3.7 7.5 6.2 0.81 9.6 2.7 1.8 2 0 0 2 2 1 0 PHD-finger WBS_methylT PF12589.8 KFH48725.1 - 1.8e-15 57.4 5.3 3.2e-15 56.6 5.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KFH48725.1 - 2.1e-11 44.3 0.0 3.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH48725.1 - 2.9e-10 40.7 0.0 7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH48725.1 - 1.6e-05 25.5 0.0 4.1e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH48725.1 - 0.00014 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFH48725.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KFH48725.1 - 0.005 16.7 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFH48725.1 - 0.04 13.2 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF2884 PF11101.8 KFH48726.1 - 0.0049 16.4 0.5 0.0094 15.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Ntox28 PF15605.6 KFH48726.1 - 0.27 11.5 3.0 1.1 9.5 1.3 2.8 2 1 1 3 3 3 0 Bacterial toxin 28 Shikimate_dh_N PF08501.11 KFH48727.1 - 5.6e-19 68.2 0.0 9.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFH48727.1 - 9.4e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain TPP_enzyme_M PF00205.22 KFH48727.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.20 KFH48727.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ecm29 PF13001.7 KFH48728.1 - 4.9e-142 474.1 0.0 5.2e-140 467.4 0.0 2.6 2 0 0 2 2 2 2 Proteasome stabiliser Sec7_N PF12783.7 KFH48728.1 - 0.042 13.7 0.2 0.25 11.3 0.2 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3385 PF11865.8 KFH48728.1 - 0.14 12.1 0.0 23 4.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 KFH48728.1 - 0.26 11.8 18.2 4.6 7.9 0.2 7.4 8 0 0 8 8 8 0 HEAT-like repeat HEAT PF02985.22 KFH48728.1 - 0.55 10.6 14.9 15 6.2 0.0 6.6 8 0 0 8 8 8 0 HEAT repeat HEAT_2 PF13646.6 KFH48728.1 - 0.66 10.4 16.4 0.75 10.2 0.1 6.1 6 0 0 6 6 6 0 HEAT repeats Nup54 PF13874.6 KFH48729.1 - 4.6e-38 130.5 1.0 4.6e-38 130.5 1.0 2.4 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KFH48729.1 - 4.7e-16 58.1 5.2 1.1e-15 56.8 5.2 1.7 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain V-SNARE_C PF12352.8 KFH48729.1 - 0.002 18.4 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus FUSC PF04632.12 KFH48729.1 - 0.013 14.1 7.7 0.021 13.4 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.13 KFH48729.1 - 0.038 14.1 0.8 0.038 14.1 0.8 3.2 2 1 1 3 3 3 0 DivIVA protein Adhesin_P1_N PF18652.1 KFH48729.1 - 0.045 13.8 2.5 0.12 12.5 2.5 1.7 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain Nucleoporin_FG PF13634.6 KFH48729.1 - 0.055 14.3 22.2 0.15 13.0 22.2 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region SesA PF17107.5 KFH48729.1 - 0.088 13.0 0.7 14 5.9 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3782 PF12644.7 KFH48729.1 - 0.16 12.1 2.0 4.1 7.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Cep57_MT_bd PF06657.13 KFH48729.1 - 0.24 11.9 7.8 0.32 11.5 0.4 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Nbl1_Borealin_N PF10444.9 KFH48729.1 - 1.6 8.5 6.1 2 8.1 0.8 2.9 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal CCDC-167 PF15188.6 KFH48729.1 - 1.7 9.0 9.7 14 6.1 4.8 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 KFH48729.1 - 1.8 7.8 11.4 1.2 8.4 0.2 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KFH48729.1 - 2 8.7 5.0 20 5.5 0.6 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CLZ PF16526.5 KFH48729.1 - 6.9 7.1 8.7 4.4 7.7 1.5 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ndc1_Nup PF09531.10 KFH48729.1 - 8.2 5.0 6.0 2 7.0 3.2 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup 2-Hacid_dh_C PF02826.19 KFH48730.1 - 1.6e-56 190.5 0.0 2.3e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFH48730.1 - 5.5e-34 116.7 0.0 6.6e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KFH48730.1 - 0.0003 20.9 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KFH48730.1 - 0.00069 19.8 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFH48730.1 - 0.0074 15.9 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Oxidored_nitro PF00148.19 KFH48730.1 - 0.039 12.7 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.21 KFH48730.1 - 0.11 11.8 1.3 1.8 7.8 1.2 2.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4690 PF15756.5 KFH48731.1 - 0.0013 19.3 0.1 0.0025 18.4 0.1 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 KFH48731.1 - 0.16 10.8 1.0 0.2 10.5 1.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adaptin_N PF01602.20 KFH48732.1 - 9.5e-120 400.6 11.0 1.1e-119 400.3 11.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFH48732.1 - 5.9e-46 155.3 0.0 1.6e-45 153.9 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFH48732.1 - 1.1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KFH48732.1 - 0.012 15.7 0.2 0.045 13.9 0.2 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 IMS PF00817.20 KFH48733.1 - 3e-38 131.2 0.0 6.7e-38 130.0 0.0 1.5 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFH48733.1 - 5.5e-13 49.6 0.1 1e-12 48.8 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFH48733.1 - 0.043 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif zf_UBZ PF18439.1 KFH48733.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Tom5 PF10642.9 KFH48734.1 - 2.5e-11 43.4 0.3 2.7e-11 43.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DHquinase_II PF01220.19 KFH48735.1 - 1.2e-62 209.7 0.0 1.3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II MFS_1 PF07690.16 KFH48738.1 - 3.3e-29 101.9 21.8 3.3e-29 101.9 21.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFH48738.1 - 5.5 5.7 10.3 0.83 8.4 2.2 2.5 3 0 0 3 3 3 0 MFS_1 like family CENP-Q PF13094.6 KFH48739.1 - 4.2e-48 163.7 0.8 4.2e-48 163.7 0.8 3.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit RFX5_DNA_bdg PF14621.6 KFH48739.1 - 4.9 6.9 39.5 2 8.2 5.4 3.7 1 1 1 3 3 3 0 RFX5 DNA-binding domain MRG PF05712.13 KFH48740.1 - 1.5e-60 203.9 0.5 2.2e-60 203.3 0.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFH48740.1 - 1.5e-06 28.0 0.2 2.9e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DENN PF02141.21 KFH48741.1 - 1.7e-59 200.9 0.0 2.7e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFH48741.1 - 3.5e-14 52.5 0.1 6.9e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KFH48741.1 - 3.9e-14 53.2 0.0 1.3e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.22 KFH48741.1 - 0.007 16.2 4.5 0.013 15.3 4.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFH48741.1 - 0.01 16.2 6.4 0.019 15.3 6.4 1.4 1 0 0 1 1 1 1 C1 domain PHD PF00628.29 KFH48741.1 - 0.02 14.8 4.8 0.043 13.7 4.8 1.6 1 0 0 1 1 1 0 PHD-finger RecR PF02132.15 KFH48741.1 - 0.14 11.7 0.5 0.3 10.7 0.5 1.5 1 0 0 1 1 1 0 RecR protein Prok-RING_1 PF14446.6 KFH48741.1 - 1.9 8.5 4.9 4.2 7.4 4.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Inositol_P PF00459.25 KFH48742.1 - 1.3e-80 270.8 0.0 1.5e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Citrate_synt PF00285.21 KFH48744.1 - 3.6e-20 72.3 0.0 1.2e-16 60.8 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KFH48744.1 - 3.9e-18 65.9 0.0 1.2e-17 64.4 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFH48744.1 - 1.2e-15 57.6 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFH48744.1 - 4.6e-06 26.5 0.0 0.00018 21.3 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Baculo_PEP_C PF04513.12 KFH48745.1 - 0.063 13.3 1.1 0.094 12.7 1.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3987 PF13148.6 KFH48745.1 - 0.97 8.4 2.8 1.1 8.2 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FAD_binding_1 PF00667.20 KFH48747.1 - 7.6e-32 110.7 0.0 1.5e-31 109.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFH48747.1 - 4.3e-30 104.8 0.0 6.5e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFH48747.1 - 1.1e-15 58.2 0.0 2.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2828 PF11443.8 KFH48748.1 - 7.6e-251 833.7 0.3 8.8e-251 833.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Methyltransf_25 PF13649.6 KFH48748.1 - 0.12 13.1 0.1 0.76 10.5 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain ALS_ss_C PF10369.9 KFH48749.1 - 1.9e-15 56.8 0.0 1.7e-14 53.8 0.0 2.3 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KFH48749.1 - 2.8e-13 49.4 0.1 4.9e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KFH48749.1 - 1.2e-07 31.4 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KFH48749.1 - 0.021 14.8 0.0 5.3 7.1 0.0 2.7 2 1 0 2 2 2 0 ACT domain p450 PF00067.22 KFH48750.1 - 1.1e-56 192.6 0.0 2.3e-56 191.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.6 KFH48751.1 - 0.0043 17.0 0.0 24 5.3 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.7 KFH48751.1 - 0.04 13.8 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 F-box-like Cnl2_NKP2 PF09447.10 KFH48752.1 - 7.1e-20 70.9 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF5082 PF16888.5 KFH48752.1 - 0.0016 18.7 0.1 0.0045 17.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KFH48752.1 - 0.0085 15.5 0.5 0.01 15.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KFH48752.1 - 0.034 14.1 1.3 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Spc19 Prefoldin_2 PF01920.20 KFH48752.1 - 0.048 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit Zip PF02535.22 KFH48753.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.13 KFH48753.1 - 0.12 13.0 2.4 0.17 12.5 1.3 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAP PF02037.27 KFH48755.1 - 8.2e-11 41.4 0.2 1.3e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 SAP domain MS_channel PF00924.18 KFH48756.1 - 2.5e-18 66.4 2.0 4.3e-18 65.6 2.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KFH48756.1 - 0.0054 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KFH48756.1 - 0.014 14.9 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KFH48756.1 - 0.023 14.6 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KFH48756.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair AMP-binding PF00501.28 KFH48757.1 - 1.9e-84 283.7 0.1 2.3e-84 283.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH48757.1 - 4.5e-27 94.8 1.0 3.4e-25 88.8 1.4 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFH48757.1 - 1.1e-19 70.1 0.5 3.2e-19 68.6 0.5 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3712 PF12505.8 KFH48758.1 - 4.1e-09 36.8 0.1 3.2e-08 33.9 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KFH48758.1 - 3.6e-05 24.2 0.0 1.1 9.8 0.0 4.2 3 1 1 4 4 4 2 Late embryogenesis abundant protein Fructosamin_kin PF03881.14 KFH48759.1 - 5.1e-31 108.0 0.0 8.7e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase AAA_16 PF13191.6 KFH48759.1 - 5.4e-06 26.9 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 KFH48759.1 - 4.7e-05 23.2 0.0 8.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 KFH48759.1 - 5.6e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain 6PF2K PF01591.18 KFH48759.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF829 PF05705.14 KFH48759.1 - 0.033 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 KFH48759.1 - 0.053 14.1 3.9 0.092 13.3 0.0 3.4 4 0 0 4 4 4 0 Alpha/beta hydrolase family NB-ARC PF00931.22 KFH48759.1 - 0.065 12.4 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 KFH48759.1 - 0.12 12.7 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SGL PF08450.12 KFH48759.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Torsin PF06309.11 KFH48759.1 - 0.2 11.7 0.0 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 Torsin CPSF73-100_C PF11718.8 KFH48761.1 - 1.1e-85 286.6 0.0 1.5e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFH48761.1 - 1.8e-30 105.4 0.0 4e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KFH48761.1 - 6.7e-19 68.7 0.8 1.4e-18 67.7 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFH48761.1 - 2.8e-18 66.1 0.1 4.8e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFH48761.1 - 1.6e-11 43.9 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFH48761.1 - 7.2e-06 25.6 0.5 1.9e-05 24.2 0.5 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFH48761.1 - 1e-05 25.5 0.2 2.5e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFH48761.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family PBP PF01161.20 KFH48762.1 - 2.2e-15 57.1 0.0 2.7e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M20 PF01546.28 KFH48763.1 - 1.4e-31 109.9 0.0 2.5e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFH48763.1 - 9.6e-12 44.8 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFH48763.1 - 0.0042 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Clr5 PF14420.6 KFH48763.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain CENP-F_C_Rb_bdg PF10490.9 KFH48763.1 - 0.15 11.5 0.1 0.48 9.9 0.1 1.8 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 IMUP PF15761.5 KFH48763.1 - 0.53 11.0 5.7 1 10.1 5.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein BTB PF00651.31 KFH48764.1 - 4.3e-25 88.1 0.0 4.2e-11 43.1 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KFH48764.1 - 1e-07 32.3 0.8 3.8e-07 30.5 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFH48764.1 - 2.2e-07 31.4 0.1 1e-06 29.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFH48764.1 - 6e-06 26.4 0.1 3.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFH48764.1 - 1.8e-05 24.7 0.5 0.2 12.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFH48764.1 - 0.0028 18.0 0.7 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Imm68 PF15583.6 KFH48764.1 - 0.081 13.1 0.1 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 68 Ribosomal_L16 PF00252.18 KFH48765.1 - 1.6e-30 105.8 0.6 2.3e-30 105.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DBR1 PF05011.13 KFH48766.1 - 2.2e-48 164.2 0.2 7.5e-48 162.5 0.0 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFH48766.1 - 0.00039 21.0 0.1 0.00064 20.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ThiF PF00899.21 KFH48767.1 - 7.2e-60 202.4 0.0 1.7e-59 201.2 0.0 1.5 1 1 1 2 2 2 1 ThiF family Rhodanese PF00581.20 KFH48767.1 - 1.1e-11 45.2 0.0 4.4e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KFH48767.1 - 0.052 13.6 0.0 0.33 11.0 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABC_tran_CTD PF16326.5 KFH48767.1 - 0.072 13.3 1.0 0.13 12.5 1.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Rpp20 PF12328.8 KFH48768.1 - 4.5e-29 101.1 2.6 5.7e-29 100.8 2.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KFH48768.1 - 2.9e-13 49.4 0.0 4.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Alba RRM_1 PF00076.22 KFH48769.1 - 3.2e-31 106.9 0.3 2.8e-15 55.9 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH48769.1 - 2.7e-05 24.2 0.0 0.048 13.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFH48769.1 - 0.00094 18.8 0.0 1 9.0 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.6 KFH48769.1 - 0.0042 16.7 0.4 0.0042 16.7 0.4 1.8 2 1 0 2 2 2 1 Putative metallopeptidase domain DbpA PF03880.15 KFH48769.1 - 0.0086 16.0 0.6 4.5 7.3 0.1 3.2 3 0 0 3 3 3 1 DbpA RNA binding domain DUF4783 PF16022.5 KFH48769.1 - 0.032 14.4 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Limkain-b1 PF11608.8 KFH48769.1 - 0.059 13.4 0.2 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Glyco_hydro_63 PF03200.16 KFH48770.1 - 5e-06 25.6 10.3 1.9e-05 23.6 0.1 3.9 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain DUF2205 PF10224.9 KFH48771.1 - 1.6e-36 124.1 0.5 2.2e-36 123.7 0.5 1.2 1 0 0 1 1 1 1 Short coiled-coil protein MTHFR PF02219.17 KFH48773.1 - 2.9e-114 381.2 0.0 4.1e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GrpE PF01025.19 KFH48774.1 - 2.1e-51 173.9 4.6 2.9e-51 173.4 4.6 1.2 1 0 0 1 1 1 1 GrpE LXG PF04740.12 KFH48774.1 - 0.0028 17.4 1.8 0.0038 17.0 1.8 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF334 PF03904.13 KFH48774.1 - 0.021 14.4 0.4 0.029 13.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) UAA PF08449.11 KFH48775.1 - 2.8e-10 39.9 18.5 3.9e-10 39.4 18.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFH48775.1 - 6.9e-05 23.0 8.6 6.9e-05 23.0 8.6 2.4 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 KFH48775.1 - 0.00053 19.4 3.5 0.00053 19.4 3.5 2.3 1 1 1 2 2 2 1 Triose-phosphate Transporter family ETF PF01012.21 KFH48776.1 - 2.4e-45 154.7 1.0 3.2e-45 154.3 1.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CN_hydrolase PF00795.22 KFH48777.1 - 2.7e-33 115.4 0.0 3.9e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFH48777.1 - 2.5e-19 69.3 0.1 1.4e-18 66.9 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFH48777.1 - 0.0023 17.6 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase Dynamin_N PF00350.23 KFH48778.1 - 4.6e-31 108.1 0.0 1.1e-30 106.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFH48778.1 - 5.4e-14 52.1 0.0 4.5e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFH48778.1 - 7.7e-05 22.7 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DotU PF09850.9 KFH48778.1 - 0.3 10.8 2.1 0.54 9.9 0.3 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU AAA_16 PF13191.6 KFH48778.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain Chromo PF00385.24 KFH48779.1 - 1.8e-07 31.0 0.2 1.6e-06 27.9 0.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain IF-2B PF01008.17 KFH48781.1 - 2.2e-75 253.5 0.9 2.5e-75 253.3 0.9 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CAP PF00188.26 KFH48782.1 - 3.2e-21 76.5 2.3 4.3e-21 76.0 2.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.11 KFH48782.1 - 0.0048 16.9 30.2 0.0048 16.9 30.2 2.3 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Fungal_trans PF04082.18 KFH48783.1 - 1.1e-07 31.1 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48783.1 - 4e-06 26.8 8.5 6.7e-06 26.1 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KFH48784.1 - 0.4 10.7 57.4 0.73 9.9 3.4 6.6 5 0 0 5 5 5 0 AT hook motif Myb_DNA-binding PF00249.31 KFH48785.1 - 1.5e-09 37.9 0.0 3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFH48785.1 - 0.022 14.7 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 Myb DNA-binding like CUB_2 PF02408.20 KFH48786.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain F-box-like PF12937.7 KFH48787.1 - 2.8e-08 33.5 0.0 5.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH48787.1 - 9.2e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 KFH48787.1 - 7.7e-05 22.3 14.5 0.00049 19.8 4.4 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif RAP80_UIM PF18282.1 KFH48787.1 - 0.023 14.5 0.1 0.1 12.4 0.1 2.1 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Casc1_N PF15927.5 KFH48787.1 - 0.28 10.8 3.5 0.46 10.2 3.5 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Abp2 PF09441.10 KFH48788.1 - 1e-75 253.5 0.0 1.7e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 RTP1_C1 PF10363.9 KFH48790.1 - 3.5e-22 78.7 0.5 2e-20 73.0 0.0 2.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KFH48790.1 - 3.6e-13 48.9 0.2 8.9e-13 47.7 0.2 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Kinesin_assoc PF16183.5 KFH48790.1 - 0.0038 17.4 0.3 0.0088 16.2 0.3 1.6 1 0 0 1 1 1 1 Kinesin-associated MMS19_C PF12460.8 KFH48790.1 - 0.036 13.2 1.9 0.13 11.3 1.2 2.1 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal V-ATPase_H_N PF03224.14 KFH48790.1 - 0.042 13.1 1.3 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 V-ATPase subunit H dsDNA_bind PF01984.20 KFH48790.1 - 0.056 13.7 1.8 0.14 12.5 1.8 1.6 1 0 0 1 1 1 0 Double-stranded DNA-binding domain RIX1 PF08167.12 KFH48790.1 - 0.1 12.3 0.2 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KFH48790.1 - 0.15 10.6 0.6 3.4 6.1 0.1 2.9 3 1 1 4 4 4 0 Adaptin N terminal region DDE_Tnp_1 PF01609.21 KFH48790.1 - 0.21 11.2 0.4 0.36 10.4 0.4 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF4778 PF16008.5 KFH48790.1 - 0.26 11.3 2.6 0.16 12.0 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) AATF-Che1 PF13339.6 KFH48790.1 - 0.51 11.0 3.3 0.35 11.6 0.8 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PBP1_TM PF14812.6 KFH48790.1 - 2.5 8.5 6.5 6.7 7.2 6.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal hDGE_amylase PF14701.6 KFH48791.1 - 1.8e-177 590.9 0.0 2.3e-177 590.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFH48791.1 - 1.6e-119 399.2 0.1 3.3e-119 398.2 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFH48791.1 - 3.9e-89 298.7 0.0 1.3e-88 297.0 0.0 1.9 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFH48791.1 - 2.9e-29 101.0 0.0 6.7e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFH48791.1 - 0.063 12.8 0.0 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, catalytic domain GATA PF00320.27 KFH48792.1 - 9.3e-31 105.1 16.3 1.1e-15 56.9 3.0 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFH48792.1 - 6.2e-06 25.6 4.7 0.018 14.5 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFH48792.1 - 9.8e-05 22.4 1.2 0.17 12.0 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KFH48792.1 - 0.0015 18.6 7.7 0.063 13.4 0.1 3.0 3 0 0 3 3 3 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KFH48792.1 - 0.03 14.5 8.6 0.37 11.0 0.6 2.6 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KFH48792.1 - 0.075 13.1 13.4 0.84 9.7 1.2 3.3 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KFH48792.1 - 0.11 12.4 11.7 0.18 11.8 0.5 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain TDP43_N PF18694.1 KFH48792.1 - 0.11 12.3 0.1 23 4.9 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain FYVE PF01363.21 KFH48792.1 - 0.26 11.5 2.2 13 6.0 0.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 KFH48792.1 - 0.33 10.4 12.1 2.5 7.6 0.5 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KFH48792.1 - 0.73 9.9 9.1 0.2 11.7 0.7 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-RRN7 PF11781.8 KFH48792.1 - 0.95 9.2 11.2 0.072 12.8 0.6 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 KFH48792.1 - 1.7 8.5 9.3 2.4 8.0 0.5 2.6 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Rubredoxin_2 PF18073.1 KFH48792.1 - 2.8 7.8 9.4 27 4.6 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain ADK_lid PF05191.14 KFH48792.1 - 5 7.2 6.1 8.1 6.5 0.2 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 KFH48792.1 - 5.7 6.8 10.8 21 5.0 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Ras PF00071.22 KFH48793.1 - 7.3e-47 159.0 0.0 9.7e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFH48793.1 - 3.3e-20 72.5 0.0 6.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFH48793.1 - 1.2e-05 24.9 0.0 3.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KFH48793.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol_phi PF04931.13 KFH48794.1 - 0.17 10.0 15.4 0.21 9.7 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 KFH48794.1 - 0.43 10.3 7.6 0.54 10.0 7.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.15 KFH48794.1 - 0.45 9.2 4.7 0.48 9.2 4.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KFH48794.1 - 0.94 7.7 11.2 1.1 7.5 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFH48794.1 - 2.2 6.4 14.7 2.4 6.2 14.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFH48794.1 - 6.7 5.9 14.3 7.7 5.7 14.3 1.1 1 0 0 1 1 1 0 BUD22 Pes-10 PF07149.11 KFH48794.1 - 8.4 5.3 9.0 11 4.9 9.0 1.1 1 0 0 1 1 1 0 Pes-10 Asp PF00026.23 KFH48796.1 - 3.5e-08 33.2 0.0 6.5e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 KFH48796.1 - 0.033 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 KFH48796.1 - 0.038 13.8 1.7 0.065 13.0 1.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ArfGap PF01412.18 KFH48797.1 - 5.9e-31 107.0 0.1 1.1e-30 106.1 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 KFH48798.1 - 3e-66 222.7 0.5 4.4e-66 222.1 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFH48798.1 - 2.2e-33 114.6 0.0 7.2e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFH48798.1 - 1.6e-21 76.1 0.0 5.3e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KFH48798.1 - 6.4e-12 45.4 0.0 2.1e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFH48798.1 - 1.4e-11 44.6 0.1 4.7e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFH48798.1 - 0.00029 20.9 0.3 0.00069 19.7 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAST_1 PF06743.15 KFH48798.1 - 0.069 13.1 0.0 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 PAD_M PF08527.10 KFH48798.1 - 0.086 12.5 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain p450 PF00067.22 KFH48799.1 - 2.6e-46 158.3 0.0 3.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 KFH48800.1 - 1e-15 58.6 0.1 1.8e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.12 KFH48800.1 - 0.0014 18.3 0.2 2.5 7.6 0.0 3.3 3 0 0 3 3 3 3 Substrate binding domain of ABC-type glycine betaine transport system NAD_binding_3 PF03447.16 KFH48800.1 - 0.012 16.2 0.3 0.019 15.6 0.3 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KFH48801.1 - 5.3e-125 417.8 16.6 6e-125 417.6 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFH48801.1 - 7.4e-23 81.0 36.4 7.8e-16 57.9 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.6 KFH48801.1 - 0.0097 16.0 1.5 0.0097 16.0 1.5 3.0 4 0 0 4 4 4 1 YtpI-like protein DUF4271 PF14093.6 KFH48801.1 - 0.23 11.4 0.1 0.23 11.4 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4271) DUF2530 PF10745.9 KFH48801.1 - 1.7 8.9 9.4 0.058 13.6 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Zip PF02535.22 KFH48802.1 - 1.2e-51 175.9 0.5 2.2e-51 175.1 0.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Sds3 PF08598.11 KFH48803.1 - 4.6e-24 85.6 12.9 5.7e-24 85.3 11.9 1.6 1 1 0 1 1 1 1 Sds3-like Acetyltransf_1 PF00583.25 KFH48804.1 - 1.9e-09 37.8 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH48804.1 - 0.004 17.6 0.0 0.0058 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFH48804.1 - 0.02 15.0 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFH48804.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFH48804.1 - 0.16 12.6 0.0 0.23 12.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFH48804.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ribosomal_L30 PF00327.20 KFH48806.1 - 3.3e-16 58.9 0.1 4.2e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SNAP PF14938.6 KFH48807.1 - 2e-115 385.1 15.4 2.3e-115 384.9 15.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFH48807.1 - 4.4e-08 33.3 8.0 0.0012 19.1 0.6 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFH48807.1 - 0.0012 18.8 14.6 0.088 13.0 0.4 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48807.1 - 0.016 15.4 14.3 0.34 11.2 0.6 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFH48807.1 - 0.066 13.3 9.3 4.4 7.6 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_long PF17177.4 KFH48807.1 - 0.12 11.7 5.1 0.061 12.7 0.4 2.4 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_1 PF00515.28 KFH48807.1 - 0.36 10.7 15.7 0.24 11.3 0.4 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFH48807.1 - 4.4 8.4 10.2 52 5.1 0.0 4.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TMEM135_C_rich PF15982.5 KFH48808.1 - 0.096 13.3 2.0 0.45 11.1 0.4 2.8 2 1 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 Not3 PF04065.15 KFH48809.1 - 0.0018 17.7 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Pox_A_type_inc PF04508.12 KFH48809.1 - 0.014 15.3 0.2 0.042 13.7 0.2 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ead_Ea22 PF13935.6 KFH48809.1 - 0.043 14.5 0.2 0.061 14.0 0.2 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein NUP PF06516.11 KFH48809.1 - 0.084 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) PFL-like PF02901.15 KFH48809.1 - 0.087 11.4 0.2 0.1 11.2 0.2 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like BLOC1_2 PF10046.9 KFH48809.1 - 0.18 12.1 1.5 0.88 9.9 0.8 2.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GP24_25 PF17388.2 KFH48810.1 - 3.7 7.5 5.1 23 5.0 0.4 2.2 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 NAD_Gly3P_dh_N PF01210.23 KFH48811.1 - 2e-45 154.6 0.1 4.4e-45 153.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFH48811.1 - 3.6e-41 140.8 0.1 5.9e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KFH48811.1 - 0.018 15.6 0.0 5.9 7.5 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HABP4_PAI-RBP1 PF04774.15 KFH48811.1 - 0.038 14.8 0.5 0.068 14.0 0.5 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Iso_dh PF00180.20 KFH48813.1 - 7.7e-78 262.1 0.0 8.9e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glu-tRNAGln PF02686.15 KFH48814.1 - 4.5e-12 46.1 0.1 8.2e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Clr2 PF10383.9 KFH48816.1 - 2.2e-07 31.7 1.7 4.4e-06 27.6 0.0 3.3 2 2 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KFH48816.1 - 1.9e-06 28.6 0.5 3.8e-06 27.6 0.5 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 2OG-FeII_Oxy PF03171.20 KFH48817.1 - 2e-14 53.9 0.0 5.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFH48817.1 - 4.2e-13 50.1 0.0 6.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ATP-synt_Eps PF04627.13 KFH48819.1 - 3.1e-24 84.7 2.2 4.4e-24 84.2 2.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Lipase_GDSL_2 PF13472.6 KFH48820.1 - 5.4e-11 43.2 0.1 9.9e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFH48820.1 - 4.2e-10 39.9 0.3 1.9e-09 37.8 0.3 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 KFH48820.1 - 0.087 12.8 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal CMAS PF02353.20 KFH48821.1 - 6e-11 42.1 0.0 1.1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KFH48821.1 - 1.2e-08 34.9 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFH48821.1 - 3.1e-08 34.2 0.1 5.6e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH48821.1 - 2e-05 25.1 0.0 3.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFH48821.1 - 2.4e-05 25.0 0.0 4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH48821.1 - 0.0035 17.2 0.0 0.0067 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFH48821.1 - 0.0075 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFH48821.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 KFH48821.1 - 0.058 13.0 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KFH48821.1 - 0.16 11.2 0.0 0.93 8.7 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Lactamase_B_4 PF13691.6 KFH48823.1 - 5.5e-20 70.8 0.1 6e-19 67.5 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KFH48823.1 - 9.1e-19 67.8 0.6 7.4e-18 64.8 0.6 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFH48823.1 - 0.0018 18.3 0.1 0.0054 16.8 0.1 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pyr_redox_2 PF07992.14 KFH48824.1 - 1.9e-48 165.2 0.0 5.1e-48 163.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFH48824.1 - 2.7e-13 50.3 0.0 5.1e-10 39.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFH48824.1 - 1.8e-06 27.4 0.0 7.4e-05 22.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFH48824.1 - 0.0032 16.6 0.9 1.1 8.2 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KFH48824.1 - 0.0037 17.5 0.1 1.3 9.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFH48824.1 - 0.032 13.5 0.1 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KFH48824.1 - 0.27 10.8 2.7 50 3.3 0.1 3.6 3 1 0 4 4 4 0 FAD dependent oxidoreductase TPR_2 PF07719.17 KFH48825.1 - 9.1e-38 125.3 7.5 8.7e-06 25.5 0.2 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFH48825.1 - 8.2e-36 120.4 6.2 2.4e-07 30.3 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFH48825.1 - 1.4e-27 95.1 7.7 7.9e-08 31.9 0.1 7.4 5 2 3 8 8 8 4 TPR repeat DnaJ PF00226.31 KFH48825.1 - 2.4e-26 91.7 1.0 7.7e-26 90.0 1.0 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KFH48825.1 - 1.2e-25 89.8 16.0 1.1e-09 38.7 0.1 6.0 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48825.1 - 3.7e-22 76.6 5.1 0.0023 18.0 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFH48825.1 - 8.5e-22 77.5 4.7 5.4e-07 30.2 1.2 5.7 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFH48825.1 - 7.2e-21 73.1 10.6 0.00098 19.8 0.9 8.5 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFH48825.1 - 2.7e-16 59.6 11.3 5.7e-05 23.3 0.4 5.5 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFH48825.1 - 4.1e-16 58.1 10.8 0.0038 17.5 0.4 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFH48825.1 - 4e-14 52.5 3.7 9.5e-07 28.9 0.1 5.3 3 3 3 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFH48825.1 - 6.5e-13 48.7 5.7 1e-05 25.7 0.3 4.2 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFH48825.1 - 1.8e-09 36.9 1.9 0.18 11.9 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFH48825.1 - 1.9e-09 37.6 17.8 0.039 14.6 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFH48825.1 - 2.9e-09 36.6 7.9 0.00079 18.7 0.7 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFH48825.1 - 8.7e-07 29.0 2.7 0.76 10.6 0.0 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFH48825.1 - 8.2e-06 26.3 7.6 0.038 14.4 0.1 4.7 2 1 2 4 4 4 2 Alkyl sulfatase dimerisation BTAD PF03704.17 KFH48825.1 - 6.8e-05 23.3 11.4 0.15 12.4 0.9 5.1 3 3 1 4 4 4 2 Bacterial transcriptional activator domain NARP1 PF12569.8 KFH48825.1 - 0.00012 21.2 3.2 0.17 10.7 0.1 3.9 2 1 2 4 4 4 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 KFH48825.1 - 0.00051 19.5 1.6 0.52 9.6 0.2 2.4 2 0 0 2 2 2 2 MalT-like TPR region MIT PF04212.18 KFH48825.1 - 0.0016 18.5 7.8 0.12 12.5 0.1 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 KFH48825.1 - 0.0017 18.6 6.0 1.1 9.6 0.1 4.7 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFH48825.1 - 0.0086 15.9 14.4 4.5 7.3 0.9 6.8 7 1 1 8 8 8 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFH48825.1 - 0.014 15.3 0.7 0.83 9.6 0.3 2.3 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal NatB_MDM20 PF09797.9 KFH48825.1 - 0.016 14.2 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit ChAPs PF09295.10 KFH48825.1 - 0.024 13.7 1.6 0.13 11.2 0.1 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 KFH48825.1 - 0.029 13.8 3.5 0.48 9.8 0.0 3.0 2 1 2 4 4 4 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 KFH48825.1 - 0.13 12.3 12.7 13 5.9 0.2 5.5 6 1 1 7 7 4 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 KFH48825.1 - 0.13 12.3 3.7 1.9 8.5 0.4 3.5 3 1 0 4 4 4 0 Putative TPR-like repeat TPM_phosphatase PF04536.14 KFH48825.1 - 0.15 12.2 2.9 9.1 6.5 0.2 3.3 2 1 1 3 3 3 0 TPM domain YfiO PF13525.6 KFH48825.1 - 0.21 11.3 9.1 0.031 14.0 1.0 2.6 3 0 0 3 3 2 0 Outer membrane lipoprotein SHNi-TPR PF10516.9 KFH48825.1 - 0.29 10.6 5.6 22 4.6 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR DUF627 PF04781.12 KFH48825.1 - 0.46 10.5 2.2 8.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF627) ERG4_ERG24 PF01222.17 KFH48826.1 - 6.5e-162 539.2 2.4 7.4e-162 539.0 2.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFH48826.1 - 0.0017 17.9 1.8 0.0033 17.0 1.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) TruD PF01142.18 KFH48827.1 - 7.6e-59 199.6 0.1 1.3e-55 188.9 0.0 3.1 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Steroid_dh PF02544.16 KFH48829.1 - 7.6e-17 61.7 0.1 1.3e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase zf-C2H2 PF00096.26 KFH48830.1 - 6.4e-06 26.3 19.4 1.9e-05 24.8 3.7 4.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH48830.1 - 4.8e-05 23.8 2.5 4.8e-05 23.8 2.5 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFH48830.1 - 7.6e-05 23.0 4.2 7.6e-05 23.0 4.2 3.6 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFH48830.1 - 0.00021 21.5 1.1 0.00072 19.8 1.1 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFH48830.1 - 0.014 15.3 2.3 0.033 14.2 2.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFH48830.1 - 0.03 14.6 3.3 0.066 13.5 1.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 KFH48830.1 - 0.083 13.3 2.2 0.15 12.5 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KFH48830.1 - 0.35 11.6 6.5 0.11 13.3 3.3 1.8 2 0 0 2 2 1 0 TRAF-type zinc finger ARS2 PF04959.13 KFH48830.1 - 1.1 9.7 5.3 5.2 7.4 5.3 2.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2HE PF16278.5 KFH48830.1 - 2 8.9 4.7 6.1 7.4 4.6 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KFH48830.1 - 3 7.8 6.4 0.63 10.0 1.8 2.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type WW PF00397.26 KFH48831.1 - 3.8e-07 30.1 2.7 9.1e-07 28.9 2.7 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KFH48831.1 - 0.079 13.3 1.0 0.16 12.4 1.0 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Glyco_hydro_129 PF11308.8 KFH48831.1 - 0.087 12.0 1.5 0.12 11.6 1.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 CorA PF01544.18 KFH48832.1 - 1.3e-06 28.0 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ERCC3_RAD25_C PF16203.5 KFH48833.1 - 5.1e-122 405.8 0.4 9.7e-122 404.9 0.4 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFH48833.1 - 4e-34 117.5 0.0 3.1e-33 114.6 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48833.1 - 2.8e-15 56.7 0.0 5.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFH48833.1 - 3e-12 46.9 0.1 8e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFH48833.1 - 3.3e-08 32.6 0.0 4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Anillin PF08174.11 KFH48834.1 - 9.9e-13 48.7 0.0 3.3e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFH48834.1 - 2e-09 37.9 0.0 6.4e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFH48834.1 - 0.036 14.5 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Metallophos PF00149.28 KFH48835.1 - 2.1e-40 139.4 0.1 2.7e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFH48835.1 - 2.9e-23 82.0 1.8 4.4e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Hat1_N PF10394.9 KFH48837.1 - 5.9e-45 153.4 0.0 9.6e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KFH48837.1 - 0.00088 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH48837.1 - 0.0078 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFH48837.1 - 0.081 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipoprotein_21 PF14041.6 KFH48837.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 LppP/LprE lipoprotein UBA PF00627.31 KFH48838.1 - 1.2e-25 89.0 9.5 1.3e-13 50.5 0.5 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KFH48838.1 - 5.9e-25 86.8 13.4 1.1e-24 85.9 13.4 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KFH48838.1 - 2.7e-20 71.9 0.2 5e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFH48838.1 - 1.6e-07 31.0 0.2 3.1e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KFH48838.1 - 0.002 17.9 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KFH48838.1 - 0.023 14.8 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like eIF-5a PF01287.20 KFH48838.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF2407 PF10302.9 KFH48838.1 - 0.098 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WIYLD PF10440.9 KFH48838.1 - 0.12 12.1 0.7 1.6 8.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ubiquitin_5 PF18037.1 KFH48838.1 - 0.15 12.4 0.4 0.28 11.6 0.4 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain FAD_binding_4 PF01565.23 KFH48839.1 - 4.2e-25 88.1 0.6 1.1e-24 86.8 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Proteasome PF00227.26 KFH48840.1 - 2e-55 187.3 0.1 2.9e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFH48840.1 - 1.2e-11 44.0 0.4 3.6e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature IL6 PF00489.17 KFH48840.1 - 0.042 13.4 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family CDI PF02234.19 KFH48840.1 - 2 8.7 4.2 5.9 7.2 1.4 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ubiq_cyt_C_chap PF03981.12 KFH48841.1 - 5.2e-35 120.6 0.2 1.6e-34 119.0 0.1 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone RicinB_lectin_2 PF14200.6 KFH48842.1 - 3.6e-06 27.6 3.2 0.0035 18.0 0.5 2.8 2 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.10 KFH48842.1 - 0.00076 18.8 0.5 0.0013 18.1 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KFH48842.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NICE-1 PF15845.5 KFH48842.1 - 0.019 15.8 2.4 0.048 14.4 2.4 1.7 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family PGF-CTERM PF18204.1 KFH48842.1 - 0.029 14.4 6.9 0.061 13.3 6.9 1.6 1 0 0 1 1 1 0 PGF-CTERM motif Rax2 PF12768.7 KFH48842.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity GT87 PF09594.10 KFH48842.1 - 0.042 13.5 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF4381 PF14316.6 KFH48842.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CoatB PF10389.9 KFH48842.1 - 0.051 13.4 1.3 0.051 13.4 1.3 2.7 3 0 0 3 3 3 0 Bacteriophage coat protein B Amidase PF01425.21 KFH48842.1 - 0.07 12.1 6.4 0.12 11.4 6.4 1.3 1 0 0 1 1 1 0 Amidase Acetyltransf_7 PF13508.7 KFH48843.1 - 2.1e-05 24.9 0.0 4.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFH48843.1 - 0.00012 22.3 0.0 0.00034 20.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFH48843.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFH48843.1 - 0.14 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Scs3p PF10261.9 KFH48844.1 - 4.8e-72 242.4 9.8 6.2e-72 242.0 9.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PHD PF00628.29 KFH48845.1 - 5.4e-09 35.8 7.1 5.4e-09 35.8 7.1 2.7 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KFH48845.1 - 1.9e-07 31.3 23.6 1.1e-06 28.9 3.4 3.8 3 1 1 4 4 4 2 Ring finger domain zf-rbx1 PF12678.7 KFH48845.1 - 2.8e-07 30.7 2.6 2.8e-07 30.7 2.6 3.3 4 0 0 4 4 4 2 RING-H2 zinc finger domain PHD_2 PF13831.6 KFH48845.1 - 9.2e-07 28.3 1.6 9.2e-07 28.3 1.6 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 KFH48845.1 - 5.7e-05 22.9 3.5 5.7e-05 22.9 3.5 2.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFH48845.1 - 0.00013 21.9 12.1 0.003 17.6 1.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KFH48845.1 - 0.0013 18.5 2.7 0.0013 18.5 2.7 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFH48845.1 - 0.0014 18.5 3.3 0.0014 18.5 3.3 3.6 4 0 0 4 4 4 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFH48845.1 - 0.0032 17.1 3.2 0.0032 17.1 3.2 3.0 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KFH48845.1 - 0.0041 16.9 3.4 0.0041 16.9 3.4 3.9 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 KFH48845.1 - 0.042 13.5 0.3 0.042 13.5 0.3 2.5 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain FAM193_C PF15914.5 KFH48845.1 - 0.054 13.2 0.8 0.13 12.0 0.8 1.7 1 0 0 1 1 1 0 FAM193 family C-terminal Prok-RING_1 PF14446.6 KFH48845.1 - 0.31 11.0 12.2 0.027 14.4 3.5 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 GAGA PF09237.11 KFH48845.1 - 0.42 10.5 3.6 8.8 6.2 0.4 3.1 2 0 0 2 2 2 0 GAGA factor PHD_3 PF13922.6 KFH48845.1 - 3.8 8.0 8.2 4 7.9 0.5 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_9 PF13901.6 KFH48845.1 - 3.8 7.4 14.6 2.4 8.1 3.5 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 KFH48845.1 - 7.1 6.6 23.5 0.15 12.0 4.1 3.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Lectin_leg-like PF03388.13 KFH48846.1 - 1.3e-60 204.6 0.1 1.8e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KFH48846.1 - 9.8e-08 31.8 0.0 5e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.10 KFH48846.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 CH PF00307.31 KFH48847.1 - 8.2e-48 161.1 0.1 7e-23 80.9 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFH48847.1 - 2.1e-27 95.0 1.0 8e-25 86.7 0.1 2.8 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KFH48847.1 - 2.8e-13 49.5 0.2 1e-06 28.5 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KFH48847.1 - 0.00028 20.6 0.9 0.003 17.4 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain Spectrin PF00435.21 KFH48847.1 - 0.0022 18.4 7.9 0.58 10.7 4.7 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_7 PF13499.6 KFH48847.1 - 0.0093 16.4 2.2 0.0093 16.4 2.2 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KFH48847.1 - 0.019 14.8 0.5 0.36 10.7 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KFH48847.1 - 0.037 13.6 0.3 0.73 9.5 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF2884 PF11101.8 KFH48847.1 - 0.69 9.4 3.4 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) G-gamma PF00631.22 KFH48848.1 - 1.2e-24 86.0 0.0 1.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain DEAD PF00270.29 KFH48849.1 - 2.4e-40 138.2 0.0 5.2e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH48849.1 - 4.7e-30 104.2 0.0 9.8e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH48849.1 - 5.8e-06 26.4 0.0 1.7e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFH48849.1 - 0.0077 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KFH48849.1 - 0.033 13.9 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase DUF3246 PF11596.8 KFH48849.1 - 0.51 9.7 1.6 0.96 8.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-C2H2 PF00096.26 KFH48850.1 - 3.6e-27 93.3 51.8 1.2e-05 25.5 0.9 10.5 10 1 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH48850.1 - 8.6e-23 79.1 53.6 0.0013 19.4 0.8 11.0 11 0 0 11 11 11 8 C2H2-type zinc finger FOXP-CC PF16159.5 KFH48850.1 - 3.3e-09 37.2 32.3 0.0066 17.1 0.1 7.8 7 1 1 8 8 8 4 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KFH48850.1 - 8.5e-09 35.4 57.4 0.00036 20.8 0.5 10.5 12 0 0 12 12 12 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFH48850.1 - 1.1e-05 25.1 0.4 1.1e-05 25.1 0.4 10.0 12 1 0 12 12 11 1 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFH48850.1 - 0.00014 22.1 17.5 0.00035 20.8 2.1 4.6 2 1 2 4 4 4 1 C2H2-type zinc ribbon zf-met PF12874.7 KFH48850.1 - 0.00024 21.4 12.7 0.94 10.0 0.0 6.8 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFH48850.1 - 0.0017 18.6 21.6 1.6 9.1 0.0 8.2 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFH48850.1 - 0.003 17.7 19.1 0.47 10.6 1.1 5.1 2 1 0 3 3 3 2 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 KFH48850.1 - 0.0033 17.0 16.3 1.2 8.8 2.0 5.2 4 1 1 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain DUF4187 PF13821.6 KFH48850.1 - 0.016 15.0 0.1 0.095 12.5 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) C1_4 PF07975.12 KFH48850.1 - 0.02 15.1 18.1 1.8 8.9 0.2 5.6 4 1 1 5 5 5 0 TFIIH C1-like domain zf_UBZ PF18439.1 KFH48850.1 - 1.2 8.8 9.8 6.1 6.5 0.1 4.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 KFH48850.1 - 1.4 9.5 7.7 12 6.5 0.1 5.1 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain IBR PF01485.21 KFH48850.1 - 3.4 8.0 24.1 18 5.6 0.3 5.1 2 2 3 5 5 5 0 IBR domain, a half RING-finger domain Fungal_trans PF04082.18 KFH48851.1 - 0.00065 18.8 0.2 0.0011 18.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH48851.1 - 0.019 15.1 1.4 0.041 14.0 1.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 KFH48853.1 - 3.8e-14 52.4 0.0 7.2e-14 51.5 0.0 1.4 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KFH48853.1 - 1.7e-11 44.5 0.0 4.1e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KFH48853.1 - 2.6e-08 34.1 0.2 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat GCV_T PF01571.21 KFH48854.1 - 3.6e-05 23.2 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Thiol_cytolys_C PF17440.2 KFH48854.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain ICMT PF04140.14 KFH48855.1 - 3.4e-28 97.9 0.2 7.3e-28 96.8 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFH48855.1 - 2.5e-09 37.5 0.5 2.5e-09 37.5 0.5 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFH48855.1 - 0.0066 16.0 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KFH48855.1 - 0.033 13.7 8.4 0.045 13.3 7.2 1.8 1 1 1 2 2 2 0 NnrU protein ATP-synt_J PF04911.12 KFH48855.1 - 0.12 12.0 2.1 1.1 8.9 0.3 2.5 2 0 0 2 2 2 0 ATP synthase j chain Zn_clus PF00172.18 KFH48856.1 - 9.4e-09 35.3 13.6 9.4e-09 35.3 13.6 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH48856.1 - 0.002 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KFH48857.1 - 7.4e-83 278.7 0.0 1.2e-82 278.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFH48857.1 - 9.9e-05 21.0 0.0 0.00015 20.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFH48857.1 - 0.0013 17.8 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFH48857.1 - 0.0057 16.0 0.2 0.0092 15.3 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family MMS1_N PF10433.9 KFH48858.1 - 4.6e-156 520.3 0.0 6.3e-156 519.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFH48858.1 - 2.1e-95 319.7 0.0 1.1e-94 317.4 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KFH48858.1 - 0.15 12.4 0.0 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ECH_1 PF00378.20 KFH48859.1 - 5.8e-77 258.4 0.1 6.6e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFH48859.1 - 5e-35 121.6 0.3 4.2e-32 112.0 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EF-hand_6 PF13405.6 KFH48860.1 - 1.3e-11 43.4 1.1 2.2e-05 24.0 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFH48860.1 - 3.2e-08 32.5 2.6 0.004 16.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFH48860.1 - 9.4e-07 29.2 3.1 2.8e-05 24.5 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFH48860.1 - 1e-05 25.3 0.1 0.073 12.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFH48860.1 - 5.7e-05 23.4 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFH48860.1 - 0.00012 21.4 4.9 0.005 16.3 0.3 2.3 2 0 0 2 2 2 2 EF hand DPM2 PF07297.12 KFH48861.1 - 1.6e-30 105.2 1.6 1.8e-30 105.0 1.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LapA_dom PF06305.11 KFH48861.1 - 0.0013 18.5 0.2 0.0021 17.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain PIG-P PF08510.12 KFH48861.1 - 0.0014 18.5 0.7 0.0015 18.4 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 KFH48861.1 - 0.0099 16.0 4.8 0.039 14.0 4.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) COX14 PF14880.6 KFH48861.1 - 0.14 12.0 1.8 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly ADH_N PF08240.12 KFH48862.1 - 2.3e-25 88.6 6.3 4e-25 87.8 6.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFH48862.1 - 7.4e-16 58.3 0.1 3.2e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFH48862.1 - 0.0017 17.8 0.2 0.0029 17.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF892 PF05974.12 KFH48862.1 - 0.22 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) UPF0242 PF06785.11 KFH48863.1 - 1.4 9.0 2.7 2.8 8.0 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 KFH48865.1 - 1.1e-27 95.7 23.9 8.7e-05 23.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48865.1 - 2.3e-11 43.8 0.2 0.55 10.6 0.0 5.9 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFH48865.1 - 0.00053 19.9 0.0 0.065 13.1 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DHFR_1 PF00186.19 KFH48866.1 - 3.2e-30 105.0 0.0 1.3e-29 103.0 0.0 2.0 1 1 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.20 KFH48866.1 - 2.7e-15 56.6 0.0 4.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Nnf1 PF03980.14 KFH48867.1 - 7.9e-34 116.3 0.5 7.9e-34 116.3 0.5 1.9 2 0 0 2 2 2 1 Nnf1 FlgN PF05130.12 KFH48867.1 - 0.082 13.4 2.7 8.5 6.9 0.3 2.5 1 1 1 2 2 2 0 FlgN protein HAUS6_N PF14661.6 KFH48867.1 - 0.11 12.0 0.5 0.39 10.3 0.5 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GrpE PF01025.19 KFH48867.1 - 0.13 12.0 0.5 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 GrpE SlyX PF04102.12 KFH48867.1 - 1.3 9.7 5.5 26 5.5 1.6 3.0 2 2 0 2 2 2 0 SlyX Arrestin_N PF00339.29 KFH48868.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Methyltransf_25 PF13649.6 KFH48869.1 - 6.7e-12 46.0 0.0 4e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFH48869.1 - 6.3e-08 33.2 0.0 7.2e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFH48869.1 - 3.3e-07 30.2 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFH48869.1 - 1.3e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFH48869.1 - 1.1e-05 25.0 0.0 0.00039 19.8 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFH48869.1 - 0.00051 20.7 0.0 0.0011 19.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFH48869.1 - 0.029 13.8 0.0 8.8 5.8 0.0 2.6 3 0 0 3 3 3 0 Putative methyltransferase MTS PF05175.14 KFH48869.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF4602 PF15375.6 KFH48870.1 - 6.4e-08 33.0 19.6 7e-07 29.6 19.6 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) CFIA_Pcf11 PF11526.8 KFH48870.1 - 0.073 13.6 4.5 0.17 12.4 4.5 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Nop14 PF04147.12 KFH48870.1 - 0.29 9.3 20.4 0.44 8.7 20.4 1.2 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.9 KFH48870.1 - 1.6 9.2 21.5 0.031 14.8 12.4 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 KFH48870.1 - 6.6 6.0 27.4 14 5.0 27.4 1.5 1 1 0 1 1 1 0 SDA1 DUF2040 PF09745.9 KFH48871.1 - 1.7e-38 131.4 18.9 1.7e-38 131.4 18.9 3.1 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.9 KFH48871.1 - 1.9 8.6 9.3 0.1 12.7 2.6 2.1 2 0 0 2 2 2 0 Apoptogenic protein 1 Ank_2 PF12796.7 KFH48872.1 - 1.6e-18 67.1 0.0 1.6e-12 47.8 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFH48872.1 - 6.9e-12 44.5 0.2 0.00054 20.2 0.1 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KFH48872.1 - 7.5e-12 45.5 0.0 9.7e-08 32.4 0.1 4.2 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFH48872.1 - 2.1e-11 43.7 3.4 0.00016 22.0 0.2 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFH48872.1 - 2e-09 37.5 3.5 0.00032 20.9 0.2 3.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) PhoLip_ATPase_C PF16212.5 KFH48874.1 - 3.7e-81 272.5 23.6 3.7e-81 272.5 23.6 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFH48874.1 - 5.2e-27 93.3 3.8 1.7e-26 91.7 3.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFH48874.1 - 5.5e-12 45.6 0.0 4.4e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFH48874.1 - 9e-10 39.2 2.4 6e-05 23.4 0.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFH48874.1 - 1e-07 31.6 0.1 2.7e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFH48874.1 - 0.0026 17.6 0.2 0.0078 16.0 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PH_9 PF15410.6 KFH48875.1 - 1.1e-07 32.3 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFH48875.1 - 0.0037 17.7 0.1 0.0065 17.0 0.1 1.4 1 0 0 1 1 1 1 PH domain DUF2587 PF10759.9 KFH48875.1 - 0.041 13.4 0.7 0.42 10.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2587) Sacchrp_dh_NADP PF03435.18 KFH48876.1 - 1.7e-16 60.7 0.0 3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KFH48876.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFH48876.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KFH48878.1 - 1.4e-25 89.9 0.0 1.2e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFH48878.1 - 4e-19 69.1 0.0 6.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH48878.1 - 0.0011 19.0 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFH48878.1 - 0.022 14.1 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) SSB PF00436.25 KFH48879.1 - 1.6e-19 69.9 0.0 1.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Stm1_N PF09598.10 KFH48880.1 - 9.5e-07 29.6 1.8 9.5e-07 29.6 1.8 3.8 4 0 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KFH48880.1 - 0.00019 22.3 8.3 0.00019 22.3 8.3 2.9 2 2 2 4 4 4 1 Hyaluronan / mRNA binding family MMR_HSR1_Xtn PF16897.5 KFH48881.1 - 6.5e-41 138.6 0.6 3.4e-40 136.3 0.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KFH48881.1 - 2e-20 73.0 0.0 6.1e-20 71.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFH48881.1 - 8.2e-19 67.4 0.0 1.7e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KFH48881.1 - 3.9e-09 36.2 0.0 1.8e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFH48881.1 - 0.00074 19.6 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KFH48881.1 - 0.0012 18.4 0.2 7.2 6.1 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFH48881.1 - 0.0091 15.0 0.1 0.027 13.4 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFH48881.1 - 0.039 13.9 0.1 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase CBS PF00571.28 KFH48881.1 - 0.099 13.1 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 CBS domain AIG1 PF04548.16 KFH48881.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family M PF02370.16 KFH48881.1 - 7.4 7.5 5.4 39 5.3 0.5 2.8 2 0 0 2 2 2 0 M protein repeat DUF543 PF04418.12 KFH48882.1 - 6.7e-29 99.7 0.0 8.6e-29 99.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pinin_SDK_memA PF04696.13 KFH48883.1 - 2.3e-33 115.0 14.9 2.3e-33 115.0 14.9 1.8 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KFH48883.1 - 1.5e-05 25.2 9.8 1.5e-05 25.2 9.8 3.8 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Ndc1_Nup PF09531.10 KFH48883.1 - 0.65 8.6 9.5 0.74 8.4 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EMC3_TMCO1 PF01956.16 KFH48883.1 - 0.86 9.3 6.4 1.5 8.6 6.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MDM10 PF12519.8 KFH48883.1 - 3.1 6.6 6.8 3.7 6.3 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FUSC PF04632.12 KFH48883.1 - 4.9 5.6 4.3 7 5.0 4.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRIMA1 PF16101.5 KFH48883.1 - 5.8 7.0 14.2 16 5.6 14.2 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dus PF01207.17 KFH48884.1 - 1.6e-62 211.4 0.0 2.4e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF2894 PF11445.8 KFH48884.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF155 PF02582.14 KFH48885.1 - 4.4e-54 183.2 0.4 5.9e-54 182.8 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3535 PF12054.8 KFH48886.1 - 3.8e-129 431.7 2.4 1.7e-128 429.6 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFH48886.1 - 5.7e-67 225.9 0.0 1.6e-66 224.5 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.22 KFH48886.1 - 4e-20 70.2 1.5 0.0075 16.4 0.0 7.9 7 0 0 7 7 7 5 HEAT repeat Helicase_C PF00271.31 KFH48886.1 - 5.9e-19 68.5 0.0 2.4e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 KFH48886.1 - 1.9e-08 34.5 6.8 0.0011 19.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFH48886.1 - 1.4e-07 32.0 0.1 0.42 11.3 0.0 4.0 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFH48886.1 - 5e-05 23.7 6.9 44 4.7 0.1 7.7 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.8 KFH48886.1 - 0.0021 17.7 0.1 1.8 8.1 0.0 3.6 2 1 1 3 3 3 2 CLASP N terminal ERCC3_RAD25_C PF16203.5 KFH48886.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 KFH48887.1 - 6.7e-09 36.2 9.6 0.066 14.1 0.1 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48887.1 - 0.00061 20.0 0.0 0.74 10.2 0.0 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 KFH48887.1 - 0.0061 16.4 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1652) PD40 PF07676.12 KFH48887.1 - 0.0078 16.1 0.8 0.21 11.6 0.2 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFH48887.1 - 0.0091 15.0 0.3 2.1 7.2 0.0 3.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TruB_C PF09142.11 KFH48887.1 - 0.012 15.3 1.7 0.67 9.8 0.1 3.9 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal DUF2457 PF10446.9 KFH48888.1 - 2.5e-169 564.3 40.9 2.5e-169 564.3 40.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 KFH48888.1 - 0.0052 16.8 17.0 0.0052 16.8 17.0 2.4 1 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 KFH48888.1 - 1.1 8.7 36.0 0.19 11.2 30.1 2.3 2 0 0 2 2 2 0 SDA1 Synaptobrevin PF00957.21 KFH48890.1 - 3e-06 26.9 6.1 0.082 12.7 0.1 4.2 1 1 3 4 4 4 3 Synaptobrevin Laminin_I PF06008.14 KFH48890.1 - 9.9e-06 25.4 8.6 0.0008 19.2 1.1 2.7 1 1 1 2 2 2 2 Laminin Domain I Alanine_zipper PF11839.8 KFH48890.1 - 2e-05 24.9 9.4 0.0051 17.2 1.0 3.2 1 1 2 3 3 3 3 Alanine-zipper, major outer membrane lipoprotein Sec34 PF04136.15 KFH48890.1 - 0.00036 20.4 3.3 0.052 13.4 0.0 2.6 1 1 2 3 3 3 3 Sec34-like family BLOC1_2 PF10046.9 KFH48890.1 - 0.0018 18.5 8.1 0.49 10.7 5.2 3.0 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 KFH48890.1 - 0.0022 18.0 4.2 0.012 15.7 0.3 2.2 1 1 1 2 2 2 2 Laminin Domain II DUF4337 PF14235.6 KFH48890.1 - 0.0061 16.7 4.3 0.0061 16.7 4.3 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4337) ZapB PF06005.12 KFH48890.1 - 0.0065 16.9 13.7 0.054 13.9 0.4 3.3 1 1 2 3 3 3 2 Cell division protein ZapB Vfa1 PF08432.10 KFH48890.1 - 0.0088 16.4 4.2 0.2 12.0 4.2 2.0 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF948 PF06103.11 KFH48890.1 - 0.012 15.8 2.3 0.21 11.8 0.2 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 KFH48890.1 - 0.014 15.2 18.7 0.21 11.4 8.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2120 PF09893.9 KFH48890.1 - 0.014 15.5 0.6 0.014 15.5 0.6 1.5 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF2935 PF11155.8 KFH48890.1 - 0.015 15.6 1.4 0.25 11.7 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) UPF0449 PF15136.6 KFH48890.1 - 0.016 15.7 8.8 0.27 11.7 0.3 3.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF3450 PF11932.8 KFH48890.1 - 0.018 14.4 7.2 0.18 11.1 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KFH48890.1 - 0.031 14.3 15.1 0.041 13.9 1.1 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3552 PF12072.8 KFH48890.1 - 0.032 13.6 12.8 3.7 6.9 12.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Nup88 PF10168.9 KFH48890.1 - 0.041 11.7 4.0 0.16 9.7 4.0 1.8 1 1 1 2 2 2 0 Nuclear pore component GldM_N PF12081.8 KFH48890.1 - 0.054 13.6 7.1 2.5 8.2 1.8 2.5 1 1 1 2 2 2 0 GldM N-terminal domain KASH_CCD PF14662.6 KFH48890.1 - 0.061 13.2 11.5 0.14 12.0 4.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1759 PF03564.15 KFH48890.1 - 0.07 13.1 0.8 0.84 9.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) NPV_P10 PF05531.12 KFH48890.1 - 0.11 12.9 3.9 2.2 8.8 0.4 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 KFH48890.1 - 0.14 11.6 11.0 0.21 11.0 9.7 1.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 KFH48890.1 - 0.14 10.0 0.3 0.18 9.7 0.3 1.2 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 KFH48890.1 - 0.21 11.8 13.9 0.46 10.7 8.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PMC2NT PF08066.12 KFH48890.1 - 0.21 12.3 6.1 0.75 10.5 2.8 2.7 1 1 1 2 2 2 0 PMC2NT (NUC016) domain JIP_LZII PF16471.5 KFH48890.1 - 0.26 11.5 9.9 3.2 8.0 0.1 3.4 4 0 0 4 4 3 0 JNK-interacting protein leucine zipper II XhlA PF10779.9 KFH48890.1 - 0.27 11.5 8.5 0.12 12.6 1.1 3.0 2 1 1 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 KFH48890.1 - 0.31 11.1 2.6 1.1 9.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFH48890.1 - 0.32 9.8 14.4 1.5 7.6 1.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4795 PF16043.5 KFH48890.1 - 0.34 10.5 10.8 2.5 7.6 10.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) EMP24_GP25L PF01105.24 KFH48890.1 - 0.57 10.1 5.3 6.3 6.7 0.5 2.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.7 KFH48890.1 - 0.66 10.1 15.7 1.1 9.4 14.7 1.9 1 1 0 1 1 1 0 Tropomyosin like Sipho_Gp157 PF05565.11 KFH48890.1 - 0.71 9.9 10.2 0.76 9.8 3.4 2.7 1 1 0 2 2 2 0 Siphovirus Gp157 DUF2205 PF10224.9 KFH48890.1 - 1.2 9.1 7.0 3.9 7.5 2.2 3.2 1 1 1 2 2 2 0 Short coiled-coil protein bZIP_1 PF00170.21 KFH48890.1 - 1.6 8.9 11.6 4.8 7.4 3.0 3.7 1 1 3 4 4 4 0 bZIP transcription factor Nup54 PF13874.6 KFH48890.1 - 1.7 8.8 7.1 1.9 8.6 4.5 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YabA PF06156.13 KFH48890.1 - 2.3 8.9 7.2 7.1 7.3 1.5 3.0 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 KFH48890.1 - 2.8 8.4 9.9 5.4 7.4 9.9 1.5 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 KFH48890.1 - 3.3 7.8 15.3 4 7.5 9.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Troponin PF00992.20 KFH48890.1 - 5 7.4 14.4 0.4 11.0 7.0 2.4 1 1 1 2 2 2 0 Troponin LPP PF04728.13 KFH48890.1 - 5.6 7.4 6.5 29 5.1 1.7 3.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 KFH48890.1 - 7.4 6.6 13.4 1.7 8.8 4.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PXA PF02194.15 KFH48891.1 - 3.2e-45 154.4 0.4 8e-45 153.0 0.1 1.9 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KFH48891.1 - 0.0011 19.5 0.0 0.0078 16.8 0.0 2.3 3 0 0 3 3 3 1 Sorting nexin C terminal PHD PF00628.29 KFH48892.1 - 8.2e-07 28.8 9.8 1.4e-06 28.1 9.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KFH48893.1 - 2.6e-06 27.2 7.2 4.5e-06 26.5 7.2 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KFH48893.1 - 0.053 14.1 0.0 0.16 12.6 0.0 1.9 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KFH48893.1 - 0.064 13.5 1.7 0.13 12.6 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SIMPL PF04402.14 KFH48893.1 - 0.52 10.7 8.0 0.078 13.4 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) SNF2_N PF00176.23 KFH48894.1 - 2.6e-72 243.5 0.3 2.6e-72 243.5 0.3 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH48894.1 - 2.3e-21 76.2 0.8 1.6e-18 67.1 0.0 4.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KFH48894.1 - 8.3e-18 64.2 0.3 2.1e-17 63.0 0.3 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KFH48894.1 - 6.9e-17 61.5 14.8 6.9e-17 61.5 14.8 4.8 5 0 0 5 5 5 1 HSA SnAC PF14619.6 KFH48894.1 - 4.4e-15 56.1 1.5 4.4e-15 56.1 1.5 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KFH48894.1 - 1.1e-11 44.3 5.2 1.1e-11 44.3 5.2 2.0 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KFH48894.1 - 8e-11 42.2 1.7 6.5e-10 39.3 0.0 3.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RBR PF17208.3 KFH48894.1 - 0.00065 20.4 5.9 0.00065 20.4 5.9 3.4 3 0 0 3 3 3 1 RNA binding Region Paf1 PF03985.13 KFH48896.1 - 3.2e-104 349.3 9.9 4e-104 349.0 9.9 1.0 1 0 0 1 1 1 1 Paf1 NAD_binding_10 PF13460.6 KFH48897.1 - 2.3e-08 34.1 0.0 9.2e-07 28.9 0.0 2.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFH48897.1 - 4e-06 26.5 0.0 7.6e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFH48897.1 - 1.6e-05 24.0 0.0 5.5e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFH48897.1 - 0.044 12.9 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFH48897.1 - 0.092 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFH48897.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KFH48897.1 - 0.23 10.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein FMN_dh PF01070.18 KFH48898.1 - 4.2e-96 322.0 0.1 2.2e-95 319.6 0.1 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFH48898.1 - 1.4e-07 31.0 0.1 2.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFH48898.1 - 8.7e-06 25.0 1.1 3e-05 23.2 0.4 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFH48898.1 - 0.035 13.5 0.3 0.077 12.4 0.3 1.6 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 KFH48898.1 - 0.066 12.5 0.3 0.93 8.7 0.1 2.6 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG DUF2347 PF09804.9 KFH48899.1 - 6.9e-106 354.0 0.0 1e-105 353.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KFH48899.1 - 7.2e-69 232.0 0.2 7.2e-69 232.0 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KFH48899.1 - 3.7e-06 25.9 0.0 0.0047 15.7 0.0 3.2 3 0 0 3 3 3 2 Transport protein Avl9 SPA PF08616.10 KFH48899.1 - 2e-05 24.5 0.0 5.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis DEAD PF00270.29 KFH48900.1 - 4.3e-46 156.9 0.2 9.1e-46 155.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFH48900.1 - 1.8e-27 95.9 0.1 9.2e-27 93.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Glyoxalase PF00903.25 KFH48900.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UTP25 PF06862.12 KFH48900.1 - 0.094 11.5 0.8 0.47 9.2 0.0 2.4 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cpn60_TCP1 PF00118.24 KFH48901.1 - 9.5e-154 512.6 5.1 1.1e-153 512.5 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 KFH48901.1 - 0.0084 16.0 0.1 6.4 6.8 0.0 2.4 2 0 0 2 2 2 2 MftR C-terminal domain FumaraseC_C PF10415.9 KFH48901.1 - 0.12 12.8 0.7 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Fumarase C C-terminus ABM PF03992.16 KFH48902.1 - 1.3e-08 34.8 0.1 1.6e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase UCR_hinge PF02320.16 KFH48902.1 - 0.0075 16.4 0.1 0.0099 16.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF3859 PF12975.7 KFH48902.1 - 0.057 13.4 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Imm8 PF15586.6 KFH48902.1 - 0.07 13.2 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 8 DUF1295 PF06966.12 KFH48903.1 - 2.8e-33 115.4 6.9 3.5e-33 115.1 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KFH48903.1 - 0.0021 18.5 0.5 0.094 13.1 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Prominin PF05478.11 KFH48904.1 - 0.16 9.9 0.3 0.21 9.5 0.3 1.1 1 0 0 1 1 1 0 Prominin DUF4083 PF13314.6 KFH48904.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PhyH PF05721.13 KFH48905.1 - 0.0012 19.2 0.0 0.0065 16.7 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PI-PLC-X PF00388.19 KFH48906.1 - 2.4e-63 212.0 0.0 3.6e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFH48906.1 - 5.6e-42 142.7 0.0 1.1e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFH48906.1 - 0.039 14.4 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like bcl-2I13 PF12201.8 KFH48907.1 - 0.028 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing NTF2 PF02136.20 KFH48908.1 - 4.3e-25 88.6 0.7 6.6e-25 88.0 0.7 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFH48908.1 - 2.7e-06 27.1 0.1 4.7e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFH48908.1 - 0.042 13.9 0.4 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif Hydrolase_6 PF13344.6 KFH48909.1 - 2.5e-26 91.7 0.0 4e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFH48909.1 - 3.8e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFH48909.1 - 9.4e-13 48.9 0.0 9.4e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFH48909.1 - 5.3e-05 23.4 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KFH48909.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) MA3 PF02847.17 KFH48910.1 - 5.2e-23 81.2 0.0 1.3e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Na_trans_assoc PF06512.13 KFH48910.1 - 0.23 11.7 4.9 0.42 10.9 4.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated FAM176 PF14851.6 KFH48910.1 - 0.54 9.9 4.9 1.4 8.6 4.9 1.7 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 KFH48910.1 - 0.58 8.6 5.3 0.81 8.2 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KFH48910.1 - 3.4 5.9 15.9 0.036 12.4 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 KFH48910.1 - 3.8 5.6 12.5 5.8 5.0 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.6 KFH48911.1 - 3.6e-86 290.4 51.2 5.3e-48 164.7 34.0 7.6 3 3 4 7 7 7 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KFH48911.1 - 3.4e-11 42.9 0.0 0.008 16.1 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat DUF919 PF06034.11 KFH48912.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PX PF00787.24 KFH48913.1 - 1.6e-14 53.8 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 PX domain U3_snoRNA_assoc PF08297.11 KFH48914.1 - 1e-16 61.4 3.2 1e-16 61.4 3.2 3.3 2 1 0 2 2 2 1 U3 snoRNA associated Presenilin PF01080.17 KFH48914.1 - 2.7 6.7 7.7 2.5 6.8 7.7 1.3 1 0 0 1 1 1 0 Presenilin DIOX_N PF14226.6 KFH48916.1 - 1.4e-23 83.9 0.1 2.6e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFH48916.1 - 2.5e-20 72.9 0.0 4.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2236 PF09995.9 KFH48917.1 - 1.5e-11 45.0 2.4 2.3e-11 44.4 2.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) adh_short PF00106.25 KFH48918.1 - 3.3e-32 111.5 0.0 4.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFH48918.1 - 5.2e-22 78.5 0.0 1.4e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFH48918.1 - 1.3e-10 41.5 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KFH48918.1 - 0.015 15.0 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 KFH48918.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KFH48918.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Raptor_N PF14538.6 KFH48918.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Ku_PK_bind PF08785.11 KFH48919.1 - 5.4e-37 126.6 0.0 1.1e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KFH48919.1 - 5.3e-27 94.9 0.0 1.1e-26 93.8 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFH48919.1 - 7.9e-12 45.4 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KFH48919.1 - 0.00013 22.3 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KFH48919.1 - 0.029 15.1 0.0 0.1 13.3 0.0 1.9 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Peptidase_M18 PF02127.15 KFH48920.1 - 4.1e-168 559.7 0.0 7.7e-168 558.7 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFH48920.1 - 1.2e-05 24.5 0.0 9.4e-05 21.6 0.0 2.3 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Rotamase_3 PF13616.6 KFH48921.1 - 1.1e-17 64.7 0.2 2e-17 63.8 0.2 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KFH48921.1 - 1.3e-15 58.1 0.1 1.7e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFH48921.1 - 2.4e-05 25.2 0.1 2.9e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PTPLA PF04387.14 KFH48922.1 - 2.4e-58 196.5 6.5 3.9e-58 195.8 6.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Nop14 PF04147.12 KFH48923.1 - 0.002 16.4 14.6 0.002 16.4 14.6 2.6 3 0 0 3 3 3 1 Nop14-like family SelB-wing_2 PF09106.11 KFH48923.1 - 0.68 10.2 2.8 9.3 6.5 0.2 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix ADD_DNMT3 PF17980.1 KFH48923.1 - 0.69 9.9 4.2 0.45 10.6 0.6 2.2 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 MFS_1 PF07690.16 KFH48924.1 - 3.4e-25 88.7 26.3 8.4e-13 48.0 4.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KFH48924.1 - 8.1e-06 24.7 0.0 8.1e-06 24.7 0.0 2.6 2 2 1 3 3 3 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 KFH48924.1 - 0.025 13.4 16.5 0.41 9.4 0.8 3.8 4 0 0 4 4 4 0 Sugar (and other) transporter MFS_1_like PF12832.7 KFH48924.1 - 0.058 12.2 8.5 1.2 7.9 0.2 3.6 2 2 1 3 3 3 0 MFS_1 like family TraL PF07178.11 KFH48924.1 - 9.9 6.7 9.2 3.9 8.0 0.1 3.3 3 0 0 3 3 3 0 TraL protein SnoaL_4 PF13577.6 KFH48925.1 - 0.0087 16.2 0.4 0.013 15.6 0.4 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KFH48925.1 - 0.0091 16.6 0.6 0.017 15.7 0.6 1.6 1 1 0 1 1 1 1 SnoaL-like domain Polyhedrin PF00738.18 KFH48925.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 1 1 2 2 2 0 Polyhedrin YEATS PF03366.16 KFH48926.1 - 4.5e-28 97.0 0.3 7.1e-28 96.4 0.3 1.3 1 0 0 1 1 1 1 YEATS family DUF641 PF04859.12 KFH48926.1 - 0.022 15.1 0.3 0.042 14.2 0.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CN_hydrolase PF00795.22 KFH48927.1 - 4.9e-41 140.8 0.0 5.7e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pam16 PF03656.13 KFH48928.1 - 4.8e-07 29.8 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KFH48928.1 - 1.3e-05 25.2 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KFH48928.1 - 0.11 12.1 0.9 0.11 12.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Pkinase PF00069.25 KFH48929.1 - 3.3e-50 170.9 0.0 1.7e-49 168.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48929.1 - 4.8e-19 68.7 0.0 3.7e-18 65.8 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase DUF2075 PF09848.9 KFH48929.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) LRR_4 PF12799.7 KFH48930.1 - 1.5e-13 50.7 10.4 0.00084 19.7 0.5 4.4 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFH48930.1 - 4.1e-12 45.7 8.2 5.2e-08 32.5 3.3 3.3 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KFH48930.1 - 8.3e-05 22.6 6.5 11 7.0 0.1 5.9 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KFH48930.1 - 0.0038 16.7 0.3 0.013 15.0 0.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFH48930.1 - 0.035 14.1 9.8 5.8 7.2 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Hom_end PF05204.14 KFH48930.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Homing endonuclease AAA PF00004.29 KFH48931.1 - 6.6e-49 165.7 0.0 4.5e-42 143.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFH48931.1 - 6.7e-08 33.1 0.2 0.00083 19.8 0.3 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KFH48931.1 - 1.3e-07 31.3 0.0 5.3e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KFH48931.1 - 5.7e-07 29.4 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFH48931.1 - 1.3e-05 25.4 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFH48931.1 - 0.0022 18.3 1.3 0.058 13.7 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFH48931.1 - 0.0029 17.6 0.0 0.014 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFH48931.1 - 0.0041 17.5 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KFH48931.1 - 0.0085 15.8 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFH48931.1 - 0.0092 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFH48931.1 - 0.011 15.8 0.4 0.031 14.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KFH48931.1 - 0.013 16.0 0.0 0.065 13.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFH48931.1 - 0.026 14.4 0.0 0.28 11.1 0.0 2.6 3 0 0 3 3 2 0 NACHT domain Mg_chelatase PF01078.21 KFH48931.1 - 0.06 12.7 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFH48931.1 - 0.063 13.5 0.8 0.27 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KFH48931.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KFH48931.1 - 0.071 12.9 0.0 6.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KFH48931.1 - 0.097 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KFH48931.1 - 0.12 12.9 0.0 0.6 10.6 0.0 2.2 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.26 KFH48931.1 - 0.13 11.9 0.0 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFH48931.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KFH48931.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KFH48931.1 - 0.67 9.7 0.0 0.67 9.7 0.0 4.0 3 1 0 3 3 2 0 AAA domain CDC37_N PF03234.14 KFH48932.1 - 4.5e-49 166.6 0.1 4.5e-49 166.6 0.1 3.2 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KFH48932.1 - 3.3e-37 127.0 0.2 8.2e-37 125.7 0.2 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KFH48932.1 - 2.9e-29 101.1 0.9 2.9e-29 101.1 0.9 2.8 2 1 0 2 2 2 1 Cdc37 C terminal domain LPD39 PF18858.1 KFH48932.1 - 0.015 15.4 4.6 1.2 9.1 0.4 3.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 39 Rx_N PF18052.1 KFH48932.1 - 0.031 14.5 0.8 0.13 12.5 0.8 2.1 1 0 0 1 1 1 0 Rx N-terminal domain eIF-3c_N PF05470.12 KFH48932.1 - 0.032 12.5 2.5 0.055 11.8 2.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus hGDE_central PF14702.6 KFH48932.1 - 0.13 12.0 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Central domain of human glycogen debranching enzyme SAPS PF04499.15 KFH48932.1 - 0.17 10.6 1.8 0.32 9.7 1.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_S8 PF00410.19 KFH48933.1 - 5.1e-22 78.2 0.0 6.9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_hydro_3_C PF01915.22 KFH48934.1 - 3.6e-43 147.9 0.0 7.4e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFH48934.1 - 4.3e-35 121.6 0.0 7.7e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFH48934.1 - 1.7e-18 66.5 0.1 3.1e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain EHN PF06441.12 KFH48935.1 - 4.7e-27 94.5 0.1 1e-26 93.4 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFH48935.1 - 2.2e-09 37.3 0.1 4e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH48935.1 - 0.00022 21.9 0.7 0.00037 21.2 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CEP170_C PF15308.6 KFH48936.1 - 0.16 10.5 3.5 0.091 11.3 1.3 1.6 2 0 0 2 2 2 0 CEP170 C-terminus ATP-synt_E PF05680.12 KFH48937.1 - 5.6e-23 81.1 0.2 6.4e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain Erf4 PF10256.9 KFH48938.1 - 5.8e-38 129.6 0.0 8.6e-38 129.0 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3602 PF12223.8 KFH48939.1 - 3.9e-09 37.0 14.3 6.1e-05 23.5 3.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KFH48939.1 - 0.089 12.4 9.0 1.5 8.4 0.3 2.9 1 1 2 3 3 3 0 GTP1/OBG Pectate_lyase_3 PF12708.7 KFH48940.1 - 1.7e-94 315.6 20.2 7e-83 277.7 6.1 3.2 4 1 1 5 5 5 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFH48940.1 - 3.4e-05 23.5 6.0 0.054 13.2 0.5 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hyd_65N_2 PF14498.6 KFH48941.1 - 2.6e-47 161.7 0.0 4.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 KFH48941.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Haspin_kinase PF12330.8 KFH48942.1 - 4.1e-31 108.3 0.0 5.5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Rdx PF10262.9 KFH48943.1 - 3.3e-33 113.7 0.0 4.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Rdx family SMC_N PF02463.19 KFH48944.1 - 2.1e-54 184.3 41.4 2e-33 115.7 11.8 2.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFH48944.1 - 9.3e-31 106.6 0.0 8.7e-30 103.4 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KFH48944.1 - 1.3e-19 71.2 37.9 3.3e-15 56.7 3.7 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KFH48944.1 - 1.1e-18 68.5 2.2 1.1e-18 68.5 2.2 7.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 KFH48944.1 - 3.4e-17 63.2 6.6 1.3e-08 35.0 0.0 3.8 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFH48944.1 - 0.00038 20.6 1.8 0.0009 19.4 0.1 2.5 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFH48944.1 - 0.0036 17.0 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HHH_3 PF12836.7 KFH48944.1 - 0.0078 16.5 0.1 1.8 8.9 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Peptidase_C71 PF12386.8 KFH48944.1 - 0.26 10.9 1.9 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei ABC_tran PF00005.27 KFH48944.1 - 0.95 10.0 0.0 0.95 10.0 0.0 6.2 3 2 0 3 3 3 0 ABC transporter Med10 PF09748.9 KFH48945.1 - 8.7e-53 177.4 0.0 1.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4972 PF16342.5 KFH48945.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF1825 PF08855.10 KFH48945.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) DUF3877 PF12993.7 KFH48945.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Herpes_LMP1 PF05297.11 KFH48946.1 - 0.045 13.0 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EphA2_TM PF14575.6 KFH48946.1 - 0.05 14.5 0.0 0.097 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFH48946.1 - 0.072 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Saf_2TM PF18303.1 KFH48946.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4381 PF14316.6 KFH48946.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Xpo1 PF08389.12 KFH48947.1 - 1.6e-35 122.4 5.5 1.7e-35 122.2 0.4 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KFH48947.1 - 0.00012 22.1 0.9 3.3 8.2 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Mce4_CUP1 PF11887.8 KFH48947.1 - 0.00061 19.3 1.5 0.0013 18.3 0.7 1.9 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative HEAT_EZ PF13513.6 KFH48947.1 - 0.002 18.6 1.8 46 4.7 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat SHR3_chaperone PF08229.11 KFH48947.1 - 0.04 12.9 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 RIX1 PF08167.12 KFH48947.1 - 0.11 12.2 0.8 1.8 8.3 0.1 3.2 2 1 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF5310 PF17237.2 KFH48947.1 - 0.14 12.0 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Amidohydro_2 PF04909.14 KFH48948.1 - 4.3e-29 102.2 0.0 5.8e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KFH48948.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Glyco_hydro_1 PF00232.18 KFH48949.1 - 1.9e-149 497.9 0.0 2.4e-149 497.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Tmemb_170 PF10190.9 KFH48951.1 - 1.3e-22 80.1 15.8 1.6e-22 79.9 15.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DAG1 PF05454.11 KFH48951.1 - 0.24 10.7 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3336 PF11815.8 KFH48952.1 - 4.3e-52 175.5 7.3 6.6e-52 174.9 7.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFH48952.1 - 4.2e-18 66.3 0.5 2e-17 64.0 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase PspB PF06667.12 KFH48952.1 - 0.91 9.6 4.8 0.46 10.6 0.5 2.4 1 1 1 2 2 2 0 Phage shock protein B DUF1682 PF07946.14 KFH48953.1 - 3.9e-110 368.1 1.3 4.5e-110 367.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Thioesterase PF00975.20 KFH48953.1 - 0.27 11.3 1.5 0.48 10.5 1.5 1.4 1 0 0 1 1 1 0 Thioesterase domain Ins_P5_2-kin PF06090.12 KFH48955.1 - 4.1e-39 135.0 0.0 1e-38 133.6 0.0 1.7 2 1 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase ubiquitin PF00240.23 KFH48956.1 - 0.0016 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KFH48956.1 - 0.03 15.0 0.0 0.063 14.0 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RIX1 PF08167.12 KFH48958.1 - 7.2e-66 221.5 0.6 4.6e-63 212.4 0.1 2.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis RNA_pol_Rpc4 PF05132.14 KFH48958.1 - 5.2 7.5 9.5 74 3.7 7.4 3.0 2 1 0 2 2 2 0 RNA polymerase III RPC4 P5CR_dimer PF14748.6 KFH48959.1 - 1.5e-30 105.5 4.2 3e-30 104.5 4.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFH48959.1 - 1.1e-11 45.2 0.3 1.2e-09 38.6 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Nuc_deoxyrib_tr PF05014.15 KFH48959.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase AMP-binding PF00501.28 KFH48960.1 - 1.2e-74 251.4 0.0 1.5e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFH48960.1 - 1e-19 71.3 0.3 2e-19 70.3 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OKR_DC_1_N PF03709.15 KFH48960.1 - 0.054 13.8 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain CAP_N PF01213.19 KFH48960.1 - 0.14 11.6 2.7 0.23 10.9 2.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KFH48960.1 - 3.3 7.8 5.5 6.2 6.9 5.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Carb_anhydrase PF00194.21 KFH48961.1 - 4.3e-32 111.6 0.0 9e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HET PF06985.11 KFH48962.1 - 7.5e-22 78.3 0.1 7.9e-21 74.9 0.1 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Thiamine_BP PF01910.17 KFH48963.1 - 4.5e-34 116.2 1.2 5.1e-34 116.0 1.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 KFH48963.1 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4745 PF15923.5 KFH48963.1 - 0.036 14.0 0.2 0.053 13.5 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) PCI PF01399.27 KFH48964.1 - 2e-08 34.7 0.1 2e-08 34.7 0.1 2.9 3 0 0 3 3 3 1 PCI domain Glyco_hydro_16 PF00722.21 KFH48967.1 - 3.9e-13 49.3 0.5 6.1e-13 48.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L12 PF00542.19 KFH48968.1 - 2.1e-19 69.6 3.9 2.1e-19 69.6 3.9 2.5 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFH48968.1 - 1.6e-10 40.5 5.9 2e-09 37.0 5.7 2.6 1 1 0 1 1 1 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KFH48968.1 - 0.038 13.8 1.0 0.15 11.9 0.1 2.3 2 1 1 3 3 3 0 Stage VI sporulation protein F TrkH PF02386.16 KFH48969.1 - 7e-147 489.9 1.3 4.6e-146 487.2 0.2 2.0 2 0 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 KFH48969.1 - 0.77 9.6 8.2 0.098 12.6 1.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal EspB_PE PF18625.1 KFH48970.1 - 0.1 13.1 0.9 0.96 9.9 0.6 2.6 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain Pox_A12 PF04651.13 KFH48970.1 - 0.19 11.8 0.4 0.38 10.8 0.4 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein His_biosynth PF00977.21 KFH48971.1 - 7.7e-35 120.4 0.0 9.3e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFH48971.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Pkinase PF00069.25 KFH48973.1 - 2.1e-57 194.5 0.0 2.6e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48973.1 - 2.7e-34 118.6 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFH48973.1 - 7.6e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFH48973.1 - 0.0014 18.3 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFH48973.1 - 0.0026 16.6 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase zf-HC5HC2H_2 PF13832.6 KFH48974.1 - 3.5e-33 114.1 7.4 3.5e-33 114.1 7.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFH48974.1 - 2.9e-31 109.0 1.2 9.4e-31 107.3 0.5 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFH48974.1 - 1.6e-25 89.2 6.8 1.6e-25 89.2 6.8 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFH48974.1 - 1.1e-14 53.6 2.2 1.1e-14 53.6 2.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFH48974.1 - 3.9e-08 33.1 28.4 6.8e-08 32.3 12.6 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KFH48974.1 - 0.013 15.1 2.0 0.013 15.1 2.0 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Stb3 PF10330.9 KFH48975.1 - 1.4e-38 130.8 0.0 2.2e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein p450 PF00067.22 KFH48976.1 - 1e-53 182.7 0.0 1.4e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_14 PF13428.6 KFH48977.1 - 0.002 18.8 5.0 0.084 13.7 1.8 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH48977.1 - 0.0032 17.2 0.2 0.15 11.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFH48977.1 - 0.005 17.1 0.7 0.011 16.0 0.7 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFH48977.1 - 0.0075 16.9 2.9 0.018 15.7 2.6 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFH48977.1 - 0.015 15.4 2.7 0.065 13.4 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFH48977.1 - 0.043 14.0 0.3 0.17 12.2 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Zip PF02535.22 KFH48978.1 - 2.5e-31 109.2 0.1 8.7e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MAP2_projctn PF08377.10 KFH48978.1 - 0.64 8.0 3.0 0.89 7.5 3.0 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain zf-CHY PF05495.12 KFH48979.1 - 1.1e-11 45.1 21.0 2.1e-11 44.1 21.0 1.5 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.12 KFH48979.1 - 2.7 8.3 16.9 2.5 8.4 0.5 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFH48979.1 - 3.9 7.7 18.1 2.2 8.5 9.9 2.6 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.19 KFH48979.1 - 4.1 7.5 12.9 20 5.3 12.9 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1899 PF08953.11 KFH48980.1 - 9.8e-34 115.1 0.1 2.1e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFH48980.1 - 7.6e-19 67.3 0.2 1.6e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFH48980.1 - 4.5e-12 46.3 3.5 6.1e-05 23.7 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFH48980.1 - 7.4e-06 26.2 0.0 0.002 18.4 0.1 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH48980.1 - 0.013 14.2 0.1 0.43 9.2 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 AlphaC_C PF17480.2 KFH48980.1 - 0.032 14.2 0.3 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 AlphaC C-terminal SlyX PF04102.12 KFH48980.1 - 0.49 11.1 5.6 0.2 12.3 0.5 2.5 2 0 0 2 2 2 0 SlyX DUF966 PF06136.13 KFH48980.1 - 1.3 8.6 7.6 2 8.1 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RL10P_insert PF17777.1 KFH48981.1 - 4.8e-21 74.5 0.0 7.9e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFH48981.1 - 4.8e-21 74.8 0.0 7.4e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 LMBR1 PF04791.16 KFH48984.1 - 1.1e-111 374.2 10.3 1.3e-111 374.0 10.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein RNA_pol_3_Rpc31 PF11705.8 KFH48985.1 - 0.006 16.9 7.7 0.006 16.9 7.7 2.7 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KFH48985.1 - 0.13 11.6 19.4 0.18 11.1 19.4 1.3 1 0 0 1 1 1 0 BUD22 DUF2151 PF10221.9 KFH48985.1 - 0.42 9.2 6.4 0.54 8.8 6.4 1.3 1 1 0 1 1 1 0 Cell cycle and development regulator Astro_capsid_p PF12226.8 KFH48985.1 - 4.8 6.2 21.9 0.03 13.5 9.6 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein RNA_pol_Rpb6 PF01192.22 KFH48986.1 - 4e-17 61.9 0.1 8.4e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 KFH48986.1 - 0.82 9.6 3.1 1.8 8.5 3.1 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Esterase PF00756.20 KFH48987.1 - 1.6e-47 162.3 0.0 1.9e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KFH48987.1 - 1.8e-05 24.3 0.0 7.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFH48987.1 - 0.00024 20.7 0.1 0.00035 20.1 0.1 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFH48987.1 - 0.0075 15.6 0.1 0.027 13.7 0.1 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KFH48987.1 - 0.044 13.3 0.1 0.082 12.4 0.1 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KFH48987.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme MRP-L46 PF11788.8 KFH48989.1 - 4.5e-24 85.5 0.0 7.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KFH48989.1 - 0.0014 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain FAD-oxidase_C PF02913.19 KFH48990.1 - 1.3e-54 185.5 0.2 2.1e-54 184.8 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFH48990.1 - 5.6e-36 123.3 0.2 1e-35 122.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2235 PF09994.9 KFH48991.1 - 8.9e-76 255.0 0.0 1.8e-75 254.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BppU_IgG PF18667.1 KFH48991.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain VasL PF12486.8 KFH48991.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL MBOAT PF03062.19 KFH48992.1 - 1.2e-21 77.5 15.8 1.2e-21 77.5 15.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KFH48992.1 - 0.0013 18.9 2.5 0.0045 17.2 2.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Phage_Mu_F PF04233.14 KFH48992.1 - 0.067 13.9 0.6 0.12 13.1 0.6 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein Dicty_REP PF05086.12 KFH48992.1 - 0.7 7.8 8.1 0.96 7.3 8.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.18 KFH48993.1 - 0.023 14.8 8.6 0.04 14.0 8.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mad3_BUB1_I PF08311.12 KFH48993.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Lipase_GDSL_2 PF13472.6 KFH48994.1 - 8.5e-06 26.3 0.0 0.00019 21.9 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family LysM PF01476.20 KFH48995.1 - 0.00015 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 KFH48995.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain PSI_integrin PF17205.3 KFH48996.1 - 0.047 13.4 0.9 0.13 12.0 0.9 1.8 1 0 0 1 1 1 0 Integrin plexin domain Zn_clus PF00172.18 KFH48996.1 - 0.32 11.2 14.4 0.16 12.1 3.7 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KFH48997.1 - 2e-14 54.1 0.2 3e-14 53.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH48997.1 - 0.00011 21.9 0.1 0.00033 20.3 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFH48997.1 - 0.00061 19.2 0.1 0.93 8.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFH48997.1 - 0.004 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFH48997.1 - 0.029 14.0 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Endonuclease_NS PF01223.23 KFH48998.1 - 6.7e-66 222.3 0.0 8e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ketoacyl-synt PF00109.26 KFH48999.1 - 2.5e-56 191.1 0.6 2.5e-56 191.1 0.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFH48999.1 - 3.3e-34 117.4 0.5 5.9e-34 116.6 0.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFH48999.1 - 0.041 13.2 0.2 0.32 10.3 0.1 2.0 2 0 0 2 2 2 0 Thiolase, N-terminal domain SNF2_N PF00176.23 KFH49000.1 - 2.3e-44 151.6 0.9 3.3e-44 151.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFH49000.1 - 3.2e-22 79.0 2.6 6e-22 78.1 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFH49000.1 - 5.9e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFH49000.1 - 0.00023 20.9 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KFH49000.1 - 0.00025 20.4 0.1 0.00052 19.3 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFH49000.1 - 0.002 17.9 0.0 0.0085 15.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase EF-hand_2 PF09068.11 KFH49000.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 EF hand U1snRNP70_N PF12220.8 KFH49001.1 - 1.2e-24 86.8 5.3 2.4e-24 85.8 5.3 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KFH49001.1 - 1.6e-12 47.1 0.1 7.5e-12 44.9 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFH49001.1 - 0.00021 21.3 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Cylicin_N PF15241.6 KFH49001.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Cylicin N-terminus zf-Tim10_DDP PF02953.15 KFH49002.1 - 4.6e-17 61.4 0.8 4.6e-17 61.4 0.8 2.1 2 0 0 2 2 2 1 Tim10/DDP family zinc finger PALP PF00291.25 KFH49003.1 - 1.3e-63 215.2 0.2 1.8e-63 214.7 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4_2 PF13923.6 KFH49003.1 - 6.8e-07 29.0 4.4 6.8e-07 29.0 4.4 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFH49003.1 - 1.6e-06 27.9 0.4 1.6e-06 27.9 0.4 3.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 KFH49003.1 - 2e-06 27.5 5.7 2e-06 27.5 5.7 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFH49003.1 - 3.5e-06 26.9 4.4 3.5e-06 26.9 4.4 4.8 6 1 1 7 7 7 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFH49003.1 - 1.5e-05 25.2 6.5 1.5e-05 25.2 6.5 4.7 4 2 0 4 4 4 1 Ring finger domain SH3_9 PF14604.6 KFH49003.1 - 2.5e-05 24.0 0.0 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_4 PF15227.6 KFH49003.1 - 0.00015 21.8 4.6 0.00015 21.8 4.6 4.9 5 2 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFH49003.1 - 0.0008 19.3 4.5 0.0008 19.3 4.5 5.8 6 0 0 6 6 6 1 zinc-RING finger domain SH3_1 PF00018.28 KFH49003.1 - 0.00097 18.7 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain 2OG-FeII_Oxy_2 PF13532.6 KFH49004.1 - 0.0021 18.3 0.2 0.23 11.6 0.1 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1138 PF06592.13 KFH49004.1 - 0.2 11.7 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) Zn_clus PF00172.18 KFH49005.1 - 1.2e-08 34.9 6.8 2.1e-08 34.1 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFH49005.1 - 0.0047 15.8 0.7 0.035 12.9 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Afi1 PF07792.12 KFH49006.1 - 2.9e-46 157.2 0.1 5.2e-46 156.4 0.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KFH49006.1 - 5.8e-36 122.9 0.0 1.1e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFH49006.1 - 3.1e-07 29.4 0.1 0.013 14.2 0.0 3.6 3 1 1 4 4 4 2 Transport protein Avl9 SPT6_acidic PF14632.6 KFH49006.1 - 0.077 13.6 13.5 0.16 12.5 13.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2347 PF09804.9 KFH49006.1 - 0.13 11.8 0.0 0.64 9.6 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF3042 PF11240.8 KFH49006.1 - 4 7.5 5.7 9 6.4 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Nucleo_P87 PF07267.11 KFH49006.1 - 4.2 6.1 4.2 6.6 5.5 4.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FXR_C1 PF16096.5 KFH49006.1 - 7.5 6.8 10.9 1.2 9.4 5.6 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 NACHT PF05729.12 KFH49007.1 - 4.1e-08 33.3 0.0 1.1e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 KFH49007.1 - 3.1e-07 30.0 0.5 5.2e-07 29.3 0.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KFH49007.1 - 4.6e-05 23.9 0.0 0.00036 21.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFH49007.1 - 0.0017 18.6 0.0 0.0054 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SesA PF17107.5 KFH49007.1 - 0.0021 18.3 1.9 0.011 15.9 1.1 2.3 2 1 1 3 3 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 KFH49007.1 - 0.0047 16.1 0.0 0.0097 15.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PilJ PF13675.6 KFH49007.1 - 0.052 13.6 1.3 0.088 12.8 0.1 2.0 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.12 KFH49007.1 - 0.07 13.6 3.1 1.5 9.4 0.4 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 KFH49007.1 - 0.075 13.5 0.1 0.76 10.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DLP_helical PF18709.1 KFH49007.1 - 0.083 12.1 0.1 0.51 9.5 0.0 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain AAA_14 PF13173.6 KFH49007.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain USP7_C2 PF14533.6 KFH49007.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal PSY3 PF16836.5 KFH49007.1 - 0.17 11.3 0.0 0.45 10.0 0.0 1.6 1 1 1 2 2 2 0 Shu complex component Psy3, DNA-binding description Noelin-1 PF12308.8 KFH49007.1 - 0.2 11.6 1.1 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF745 PF05335.13 KFH49007.1 - 0.23 11.1 1.6 0.79 9.4 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 KFH49007.1 - 4.9 7.2 10.4 28 4.7 0.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L37ae PF01780.19 KFH49008.1 - 8.9e-40 134.7 10.6 9.9e-40 134.5 10.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KFH49008.1 - 0.0012 19.0 1.9 0.0017 18.5 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Sgf11 PF08209.11 KFH49008.1 - 0.033 13.7 1.2 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_Tnp_IS1595 PF12760.7 KFH49008.1 - 0.042 13.8 2.4 0.074 13.0 2.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1451 PF07295.11 KFH49008.1 - 0.095 12.7 0.7 0.13 12.2 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_2 PF03107.16 KFH49008.1 - 0.1 12.9 1.9 4 7.8 0.1 2.1 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 KFH49008.1 - 0.27 11.3 5.0 0.35 10.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger FMO-like PF00743.19 KFH49010.1 - 9.8e-17 60.6 0.0 6.7e-13 47.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFH49010.1 - 6e-13 48.8 0.0 1.5e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFH49010.1 - 5.1e-06 25.9 0.0 0.0054 15.9 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFH49010.1 - 1.4e-05 24.5 0.0 5e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFH49010.1 - 1.8e-05 24.1 0.0 6e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFH49010.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFH49010.1 - 9.1e-05 22.5 0.0 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFH49010.1 - 0.021 14.1 0.0 0.083 12.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family GSH_synth_ATP PF03917.17 KFH49012.1 - 3.9e-138 460.3 0.0 4.5e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFH49012.1 - 3e-32 111.1 0.0 5.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Aldedh PF00171.22 KFH49013.1 - 2.5e-168 560.3 0.0 3.2e-168 560.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAUS6_N PF14661.6 KFH49014.1 - 0.027 14.0 0.3 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.8 KFH49014.1 - 0.14 11.5 4.5 0.22 10.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PspB PF06667.12 KFH49014.1 - 0.15 12.1 6.2 0.26 11.3 6.2 1.4 1 0 0 1 1 1 0 Phage shock protein B bZIP_2 PF07716.15 KFH49014.1 - 0.52 10.4 20.7 0.96 9.6 20.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF2183 PF09949.9 KFH49015.1 - 5.4e-31 106.9 0.0 1.5e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KFH49015.1 - 0.00023 20.7 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) STE PF02200.16 KFH49016.1 - 3e-48 162.8 0.1 4.7e-48 162.2 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-H2C2_2 PF13465.6 KFH49016.1 - 1.6e-07 31.4 2.5 1.6e-07 31.4 2.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFH49016.1 - 1.8e-05 25.0 13.2 0.0034 17.7 3.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFH49016.1 - 0.0039 17.9 12.8 0.034 15.0 2.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KFH49016.1 - 0.1 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon HTH_Tnp_Tc5 PF03221.16 KFH49017.1 - 2.8e-11 43.3 0.0 1.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFH49017.1 - 1.7e-09 37.2 0.1 3.1e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KFH49017.1 - 0.0033 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KFH49017.1 - 0.0074 16.1 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.22 KFH49017.1 - 0.083 12.8 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_Tnp_4 PF13613.6 KFH49017.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease SPX PF03105.19 KFH49018.1 - 3.5 7.5 6.9 5.6 6.8 6.9 1.3 1 0 0 1 1 1 0 SPX domain AMP-binding PF00501.28 KFH49019.1 - 1.5e-68 231.4 1.0 1.1e-25 90.1 0.0 4.6 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 KFH49019.1 - 3.1e-11 44.1 0.1 9.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 KFH49019.1 - 0.00016 21.6 0.3 0.00038 20.4 0.3 1.6 1 0 0 1 1 1 1 Gas vesicle protein G Big_2 PF02368.18 KFH49019.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Ecl1 PF12855.7 KFH49020.1 - 2.2e-33 116.9 18.8 2.2e-33 116.9 18.8 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins DUF2256 PF10013.9 KFH49020.1 - 0.91 9.7 4.7 4.7 7.4 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FLZ PF04570.14 KFH49020.1 - 1 8.9 5.1 3.1 7.3 5.1 1.7 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Ribosomal_L19 PF01245.20 KFH49021.1 - 1.2e-08 34.8 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Glyco_hydro_61 PF03443.14 KFH49022.1 - 3.7e-55 187.0 0.3 4.8e-55 186.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MSA-2c PF12238.8 KFH49022.1 - 2.2 8.2 7.2 3.5 7.6 7.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c BP28CT PF08146.12 KFH49023.1 - 1.6e-43 148.3 0.1 1.9e-42 144.8 0.1 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KFH49023.1 - 2.2e-25 89.2 7.3 6.2e-25 87.8 0.1 5.1 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KFH49023.1 - 4.9e-06 26.4 9.3 0.031 14.5 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KFH49023.1 - 3.7e-05 24.0 12.5 0.4 11.1 0.6 6.8 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KFH49023.1 - 0.0069 16.9 12.5 0.8 10.3 0.2 6.9 5 3 3 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 KFH49023.1 - 0.051 13.8 1.1 1.2 9.3 0.1 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KFH49023.1 - 0.29 10.4 4.8 0.29 10.4 0.7 3.1 3 0 0 3 3 3 0 V-ATPase subunit H WD40 PF00400.32 KFH49024.1 - 4.3e-32 109.6 18.3 1.9e-07 31.6 0.0 7.4 8 0 0 8 8 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KFH49024.1 - 1.3e-11 44.2 0.7 2.8e-11 43.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFH49024.1 - 3.2e-08 33.2 0.1 6.7e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KFH49024.1 - 9.4e-08 32.3 0.2 0.012 15.8 0.0 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFH49024.1 - 0.00038 19.3 1.6 0.76 8.3 0.0 3.9 1 1 3 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KFH49024.1 - 0.025 14.2 0.1 0.48 10.0 0.1 2.6 1 1 1 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KFH49024.1 - 0.025 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 F-box Cytochrom_D1 PF02239.16 KFH49024.1 - 0.041 12.4 0.1 0.13 10.8 0.1 1.8 1 0 0 1 1 1 0 Cytochrome D1 heme domain STE PF02200.16 KFH49024.1 - 0.086 13.3 0.1 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 STE like transcription factor Nucleoporin_N PF08801.11 KFH49024.1 - 0.096 11.4 0.1 14 4.2 0.0 2.7 3 1 0 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KFH49024.1 - 0.2 10.6 0.1 0.78 8.6 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein iPGM_N PF06415.13 KFH49025.1 - 4.9e-76 254.9 0.0 7.4e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KFH49025.1 - 3.1e-65 220.0 0.0 3.6e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFH49025.1 - 1.4e-08 34.8 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFH49025.1 - 4.9e-06 26.2 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFH49025.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 PglZ domain ATP-synt_DE_N PF02823.16 KFH49026.1 - 6.5e-17 61.2 0.1 9.3e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain STE3 PF02076.15 KFH49027.1 - 6.2e-66 222.6 14.4 7.8e-66 222.2 14.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 KFH49027.1 - 0.0088 15.4 9.0 0.016 14.5 9.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4260 PF14079.6 KFH49027.1 - 0.23 11.4 2.4 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) zf-Mss51 PF13824.6 KFH49028.1 - 1.2e-30 105.3 6.5 2.3e-30 104.5 6.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KFH49028.1 - 0.0031 17.5 0.2 0.0031 17.5 0.2 1.8 2 0 0 2 2 2 1 MYND finger DUF1610 PF07754.11 KFH49028.1 - 0.056 13.4 1.5 0.099 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Iso_dh PF00180.20 KFH49029.1 - 1.6e-127 425.5 0.0 1.8e-127 425.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Urb2 PF10441.9 KFH49030.1 - 4.2e-59 199.9 0.6 1.6e-58 198.0 0.0 2.4 3 0 0 3 3 3 1 Urb2/Npa2 family DUF1870 PF08965.10 KFH49030.1 - 3 7.9 4.7 4.2 7.4 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1870) Abhydrolase_1 PF00561.20 KFH49032.1 - 1.5e-24 87.1 0.1 1.6e-19 70.6 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFH49032.1 - 2.8e-17 64.1 2.4 5.1e-17 63.2 2.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFH49032.1 - 7.2e-13 48.3 0.0 2.3e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFH49032.1 - 0.062 12.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DnaJ PF00226.31 KFH49034.1 - 3.9e-17 62.1 1.1 1.1e-16 60.6 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFH49034.1 - 1.3e-10 40.9 0.0 1.6e-05 24.2 0.0 2.5 3 0 0 3 3 3 2 Sec63 Brl domain CDC45 PF02724.14 KFH49034.1 - 7.7 4.7 6.5 15 3.8 6.5 1.4 1 0 0 1 1 1 0 CDC45-like protein EB1 PF03271.17 KFH49035.1 - 1e-16 60.9 2.7 2.2e-16 59.8 2.7 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KFH49035.1 - 1.7e-07 31.3 1.0 3.1e-07 30.6 1.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KFH49035.1 - 0.0035 17.4 0.4 0.0054 16.8 0.4 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein HMG_box PF00505.19 KFH49036.1 - 1.3e-05 25.5 0.5 4.5e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box CCDC106 PF15794.5 KFH49036.1 - 0.0033 17.2 0.8 0.0033 17.2 0.8 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 106 HMG_box_2 PF09011.10 KFH49036.1 - 0.0035 17.9 0.5 0.0035 17.9 0.5 2.2 2 1 0 2 2 2 1 HMG-box domain SAD_SRA PF02182.17 KFH49037.1 - 6.9e-08 32.3 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Endonuc_Holl PF10107.9 KFH49037.1 - 7.1 6.5 5.9 2.9 7.7 3.3 1.6 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Acyltransferase PF01553.21 KFH49039.1 - 2.4e-32 111.4 0.0 3.9e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 KFH49039.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP Topoisom_bac PF01131.20 KFH49040.1 - 3.4e-104 349.1 0.0 3.2e-99 332.7 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KFH49040.1 - 8.5e-17 61.3 0.0 1.8e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EBV-NA1 PF02905.14 KFH49040.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain bZIP_1 PF00170.21 KFH49041.1 - 3.5e-06 27.0 6.1 3.5e-06 27.0 6.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF5595 PF18077.1 KFH49041.1 - 0.23 11.5 0.8 0.61 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) bZIP_2 PF07716.15 KFH49041.1 - 0.31 11.1 8.7 0.14 12.3 5.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 KFH49041.1 - 0.35 10.8 2.6 0.61 10.0 2.2 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.6 KFH49041.1 - 3.6 6.9 4.8 4.2 6.6 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4203 PF13886.6 KFH49042.1 - 1.4e-53 181.5 25.3 1.8e-53 181.2 25.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) OAD_gamma PF04277.13 KFH49042.1 - 0.7 10.5 4.4 3.2 8.4 0.1 3.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4451 PF14616.6 KFH49043.1 - 4e-25 88.4 0.1 6.6e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) L51_S25_CI-B8 PF05047.16 KFH49044.1 - 3.3e-15 55.7 0.0 7.4e-15 54.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GHL10 PF02638.15 KFH49044.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 WD40 PF00400.32 KFH49046.1 - 6.7e-09 36.2 12.5 0.007 17.2 0.3 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Rer1 PF03248.13 KFH49048.1 - 7.2e-78 260.2 10.6 8.3e-78 260.0 10.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 KFH49048.1 - 0.38 10.4 6.4 0.27 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CIAPIN1 PF05093.13 KFH49049.1 - 8.5e-39 132.1 3.3 1.4e-38 131.4 3.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KFH49049.1 - 1.3e-33 116.0 0.0 1.8e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus VirE PF05272.11 KFH49049.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Hom_end PF05204.14 KFH49049.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Homing endonuclease Arf PF00025.21 KFH49050.1 - 1.5e-66 223.1 0.0 1.7e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFH49050.1 - 3.3e-10 39.7 0.1 1.3e-06 27.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFH49050.1 - 6.2e-08 32.3 0.0 8.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFH49050.1 - 9.6e-08 32.3 0.0 3.2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFH49050.1 - 2e-07 30.7 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFH49050.1 - 3.5e-07 30.3 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFH49050.1 - 2.4e-05 23.8 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFH49050.1 - 0.0038 16.8 0.1 0.14 11.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF4149 PF13664.6 KFH49051.1 - 7.7e-25 87.2 4.5 8.5e-25 87.0 2.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KFH49051.1 - 0.0014 18.9 0.1 0.002 18.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5510 PF17629.2 KFH49051.1 - 0.097 12.6 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Fungal_trans PF04082.18 KFH49052.1 - 1.2e-18 67.1 0.1 2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFH49052.1 - 1.4e-05 25.1 15.4 2.8e-05 24.2 15.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_MA PF01140.19 KFH49052.1 - 0.011 15.4 0.2 0.079 12.7 0.1 2.1 2 0 0 2 2 2 0 Matrix protein (MA), p15 DUF883 PF05957.13 KFH49052.1 - 0.011 16.3 2.0 0.017 15.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Duffy_binding PF05424.11 KFH49052.1 - 0.58 10.2 2.0 4.4 7.3 0.3 2.2 2 0 0 2 2 2 0 Duffy binding domain Asp-B-Hydro_N PF05279.11 KFH49053.1 - 1.6 8.7 30.9 2.4 8.2 30.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 KFH49053.1 - 6.9 5.0 29.8 9.2 4.6 29.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PH_10 PF15411.6 KFH49054.1 - 7.1e-28 97.3 0.3 1.2e-27 96.6 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KFH49054.1 - 2.1e-14 54.1 0.0 3.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFH49054.1 - 2e-10 40.9 0.1 5.8e-10 39.3 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KFH49054.1 - 0.0004 20.6 5.6 0.00071 19.9 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFH49054.1 - 0.0026 17.7 5.5 0.0043 17.0 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFH49054.1 - 0.017 15.4 2.6 0.038 14.3 2.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFH49054.1 - 0.021 14.7 4.6 0.038 13.8 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFH49054.1 - 0.078 12.6 6.5 0.023 14.3 3.5 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFH49054.1 - 0.08 13.3 4.5 0.15 12.4 4.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KFH49054.1 - 0.09 12.7 5.2 0.16 11.8 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFH49054.1 - 0.096 12.5 3.7 0.24 11.2 3.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF1147 PF06615.11 KFH49054.1 - 0.22 11.6 0.4 0.49 10.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 KFH49054.1 - 1.3 9.1 5.5 2.8 8.1 5.5 1.6 1 0 0 1 1 1 0 Zinc-finger PDEase_II PF02112.15 KFH49057.1 - 9.5e-52 176.2 0.0 1.2e-19 70.6 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KFH49057.1 - 0.056 13.4 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily BCNT PF07572.12 KFH49059.1 - 6.1e-22 77.5 1.1 1.4e-21 76.3 1.1 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development SYF2 PF08231.12 KFH49061.1 - 2e-56 190.8 15.0 2e-56 190.8 15.0 2.1 2 0 0 2 2 2 1 SYF2 splicing factor DsbG_N PF18257.1 KFH49061.1 - 0.11 12.7 0.6 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Mannosidase_ig PF17786.1 KFH49063.1 - 5.2e-20 71.9 0.8 1.2e-18 67.5 0.1 3.2 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFH49063.1 - 2.2e-09 38.0 0.0 6.8e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFH49063.1 - 0.0049 16.6 0.1 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KFH49063.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3439 PF11921.8 KFH49063.1 - 0.028 14.4 0.3 0.06 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_2_N PF02837.18 KFH49063.1 - 0.038 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Nbl1_Borealin_N PF10444.9 KFH49063.1 - 0.042 13.5 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal FemAB_like PF04339.12 KFH49063.1 - 0.055 12.6 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Arf PF00025.21 KFH49064.1 - 8e-59 198.0 0.4 9.1e-59 197.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFH49064.1 - 7.4e-10 39.1 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFH49064.1 - 5.3e-09 35.9 0.0 6.1e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFH49064.1 - 5.8e-09 35.6 0.5 0.0016 17.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFH49064.1 - 7.3e-08 32.1 0.0 9.3e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFH49064.1 - 8.7e-07 28.5 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFH49064.1 - 4.7e-06 26.7 0.0 7.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFH49064.1 - 0.017 15.2 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KFH49064.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KFH49064.1 - 0.13 11.2 0.1 0.54 9.2 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 KFH49064.1 - 0.18 11.1 0.1 0.41 9.9 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Eno-Rase_FAD_bd PF07055.12 KFH49064.1 - 0.25 11.8 0.8 4.1 7.9 0.0 2.6 3 0 0 3 3 2 0 Enoyl reductase FAD binding domain Whi5 PF08528.11 KFH49065.1 - 7.5e-09 35.0 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Cwf_Cwc_15 PF04889.12 KFH49065.1 - 0.051 13.3 9.8 0.012 15.3 6.8 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.26 KFH49066.1 - 8.1e-29 99.2 1.0 1e-28 98.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KFH49066.1 - 0.079 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain APH PF01636.23 KFH49067.1 - 3.1e-10 40.4 0.2 5.8e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFH49067.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase IcmF-related PF06761.12 KFH49067.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing EcKinase PF02958.20 KFH49067.1 - 0.22 10.8 0.0 1.2 8.3 0.0 2.1 2 1 1 3 3 3 0 Ecdysteroid kinase Actin PF00022.19 KFH49068.1 - 4e-29 101.5 0.0 1.2e-17 63.6 0.0 2.9 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KFH49068.1 - 0.00015 21.1 0.3 0.26 10.4 0.1 2.4 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KFH49068.1 - 0.0003 21.2 0.0 0.014 15.8 0.0 2.5 3 0 0 3 3 3 1 Cell division protein FtsA MreB_Mbl PF06723.13 KFH49068.1 - 0.0071 15.2 0.0 0.04 12.7 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein NRDE-2 PF08424.10 KFH49069.1 - 2.3e-99 332.5 5.0 2.7e-98 329.1 3.7 2.5 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFH49069.1 - 0.00041 20.9 0.1 19 6.4 0.0 5.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFH49069.1 - 0.034 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFH49069.1 - 0.11 12.9 1.3 0.48 10.9 0.2 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Trp_DMAT PF11991.8 KFH49070.1 - 6.5e-90 302.2 0.0 8e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase OPT PF03169.15 KFH49072.1 - 1e-184 615.7 44.9 1.2e-184 615.5 44.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mtc PF03820.17 KFH49073.1 - 2.4e-114 381.6 0.0 2.7e-114 381.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PhnH PF05845.12 KFH49073.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Glyco_transf_90 PF05686.12 KFH49074.1 - 1.2e-14 54.1 2.5 5.7e-11 42.0 0.7 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 TIM PF00121.18 KFH49076.1 - 5.2e-88 294.5 0.9 5.9e-88 294.3 0.9 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EF-hand_13 PF17958.1 KFH49076.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain STT3 PF02516.14 KFH49077.1 - 4e-143 477.9 34.2 2e-138 462.4 31.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Abhydrolase_6 PF12697.7 KFH49078.1 - 0.00031 21.4 2.3 0.00062 20.4 1.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KFH49078.1 - 0.0035 17.1 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFH49078.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KFH49078.1 - 0.028 13.7 0.3 0.087 12.1 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFH49078.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-C2H2 PF00096.26 KFH49081.1 - 0.016 15.7 3.5 0.039 14.4 3.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFH49081.1 - 0.37 11.3 3.0 5.5 7.6 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFH49081.1 - 1.8 9.6 4.0 4.8 8.3 4.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4484 PF14831.6 KFH49082.1 - 1.7e-17 64.2 0.9 2e-17 64.0 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) PHF5 PF03660.14 KFH49084.1 - 8.4e-53 177.0 9.7 9.6e-53 176.8 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KFH49084.1 - 0.34 8.7 6.7 0.36 8.7 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KFH49084.1 - 2.4 8.3 15.7 5.7 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon CAF1 PF04857.20 KFH49085.1 - 1.5e-54 185.3 0.0 2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.24 KFH49085.1 - 0.065 13.8 0.0 0.88 10.1 0.0 2.2 2 0 0 2 2 2 0 Exonuclease SGL PF08450.12 KFH49086.1 - 1e-63 215.2 0.0 1.4e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KFH49086.1 - 0.0021 18.1 0.0 0.0055 16.7 0.0 1.6 1 1 1 2 2 2 1 Esterase-like activity of phytase Arylesterase PF01731.20 KFH49086.1 - 0.041 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Lactonase PF10282.9 KFH49086.1 - 0.088 12.0 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Reg_prop PF07494.11 KFH49086.1 - 0.13 12.6 0.5 26 5.5 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller RTA1 PF04479.13 KFH49088.1 - 4.4e-67 225.7 10.2 7e-67 225.0 10.2 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.9 KFH49088.1 - 0.04 13.9 2.2 0.089 12.8 2.2 1.6 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) WD40 PF00400.32 KFH49089.1 - 2.3e-08 34.5 9.5 0.58 11.1 0.0 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat SBF_like PF13593.6 KFH49091.1 - 1.3e-88 297.3 16.3 1.5e-88 297.1 16.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KFH49091.1 - 2.6e-09 37.0 9.2 6.4e-09 35.8 9.2 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family FapA PF03961.13 KFH49092.1 - 6e-05 21.8 1.2 6.9e-05 21.6 1.2 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Bactofilin PF04519.13 KFH49092.1 - 0.0001 22.5 1.5 0.0023 18.2 1.2 2.2 1 1 0 1 1 1 1 Polymer-forming cytoskeletal MinC_C PF03775.16 KFH49092.1 - 0.43 10.6 2.0 8.3 6.5 1.7 2.8 1 1 2 3 3 3 0 Septum formation inhibitor MinC, C-terminal domain PUF PF00806.19 KFH49093.1 - 3.7e-30 101.9 6.2 3.9e-05 23.1 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat PalH PF08733.10 KFH49094.1 - 0.29 10.1 4.3 0.35 9.8 4.3 1.0 1 0 0 1 1 1 0 PalH/RIM21 Nucleoside_tran PF01733.18 KFH49095.1 - 4.8e-39 134.6 6.0 2.7e-37 128.8 6.0 2.7 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KFH49095.1 - 1.4e-07 30.7 28.2 0.00045 19.3 3.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily HK PF02110.15 KFH49096.1 - 2.2e-75 253.2 5.1 3.5e-75 252.6 5.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KFH49096.1 - 3.4e-58 196.0 1.7 7.6e-58 194.8 1.7 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KFH49096.1 - 0.00044 19.7 2.1 0.00056 19.4 0.3 2.0 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase Zn_clus PF00172.18 KFH49097.1 - 4.5e-13 49.1 30.9 2.3e-07 30.8 12.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFH49097.1 - 4.4e-11 42.3 0.4 6.6e-11 41.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.31 KFH49099.1 - 3.3e-14 52.8 0.4 9e-13 48.2 0.0 2.8 3 0 0 3 3 3 1 DnaJ domain Presenilin PF01080.17 KFH49099.1 - 2.4 6.8 6.4 2.9 6.5 6.4 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 KFH49099.1 - 7.5 4.3 5.8 9.7 4.0 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CTK3 PF12243.8 KFH49100.1 - 3.1e-48 162.8 0.1 4.6e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KFH49100.1 - 1.6e-19 69.8 7.9 1.6e-19 69.8 7.9 1.7 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Rcd1 PF04078.13 KFH49100.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like GFA PF04828.14 KFH49101.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Catalase PF00199.19 KFH49103.1 - 1.7e-165 550.8 0.0 2.4e-165 550.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KFH49103.1 - 2.4e-47 160.4 0.1 3.7e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KFH49103.1 - 1e-19 70.5 0.0 2.3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Eno-Rase_FAD_bd PF07055.12 KFH49103.1 - 0.14 12.6 0.3 16 6.0 0.2 2.8 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Isochorismatase PF00857.20 KFH49104.1 - 9.2e-21 74.8 0.4 2.8e-20 73.2 0.4 1.7 1 1 0 1 1 1 1 Isochorismatase family Biotin_lipoyl PF00364.22 KFH49105.1 - 9e-21 73.5 0.5 1.9e-20 72.4 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFH49105.1 - 7.8e-10 38.9 1.4 1.7e-09 37.9 0.2 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFH49105.1 - 0.0034 17.2 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KFH49105.1 - 0.031 15.0 0.2 0.98 10.2 0.0 2.7 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.16 KFH49105.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1640 PF07798.11 KFH49106.1 - 4.7e-47 160.3 5.3 6.6e-47 159.8 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SOG2 PF10428.9 KFH49106.1 - 0.12 11.6 9.8 0.16 11.2 9.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pneumo_att_G PF05539.11 KFH49106.1 - 0.19 11.3 8.2 0.28 10.7 8.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G dCache_2 PF08269.11 KFH49106.1 - 0.36 10.0 2.8 0.76 8.9 2.8 1.6 1 0 0 1 1 1 0 Cache domain DUF1664 PF07889.12 KFH49106.1 - 0.39 10.8 5.1 0.089 12.8 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3123 PF11321.8 KFH49106.1 - 0.44 11.2 2.4 1.2 9.9 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF4407 PF14362.6 KFH49106.1 - 1.6 8.0 9.1 3.2 7.0 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_14 PF13428.6 KFH49107.1 - 1e-07 32.1 22.9 0.0049 17.6 0.2 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFH49107.1 - 6.7e-07 29.0 1.1 0.036 14.3 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFH49107.1 - 3.2e-06 27.1 0.8 0.0073 16.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFH49107.1 - 4.3e-06 26.4 10.1 0.034 14.3 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFH49107.1 - 1.5e-05 25.4 4.1 0.015 15.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFH49107.1 - 0.00012 22.1 4.5 1.4 9.1 0.7 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFH49107.1 - 0.00023 20.9 2.0 0.52 10.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFH49107.1 - 0.0004 20.2 7.4 3 8.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFH49107.1 - 0.017 15.4 13.0 2.7 8.3 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFH49107.1 - 0.028 15.0 18.4 0.15 12.8 0.5 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFH49107.1 - 0.24 12.1 3.6 0.79 10.5 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_5 PF07728.14 KFH49108.1 - 4.6e-124 408.9 0.0 3.6e-21 75.6 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFH49108.1 - 1.1e-55 186.4 12.4 8e-25 87.1 0.0 5.4 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_3 PF07726.11 KFH49108.1 - 3.1e-31 107.9 0.0 6.4e-10 39.0 0.0 7.5 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KFH49108.1 - 1.4e-30 105.5 1.2 9.1e-30 102.9 0.0 3.0 3 0 0 3 3 2 1 Midasin AAA lid domain AAA PF00004.29 KFH49108.1 - 5.7e-29 101.2 0.0 0.00012 22.6 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFH49108.1 - 8.6e-28 97.1 0.9 3.8e-05 23.3 0.0 7.0 6 1 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 KFH49108.1 - 4.4e-27 95.5 15.1 2.8e-05 24.6 0.4 8.9 7 2 0 7 7 6 6 AAA ATPase domain Dynein_heavy PF03028.15 KFH49108.1 - 5.8e-26 90.9 0.0 0.0012 18.9 0.0 8.0 7 0 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KFH49108.1 - 7.1e-22 77.8 0.0 0.0072 15.3 0.0 8.7 8 1 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KFH49108.1 - 5.1e-20 72.1 0.6 0.0063 16.8 0.0 8.6 7 0 0 7 7 7 4 AAA domain Sigma54_activat PF00158.26 KFH49108.1 - 2.5e-18 66.3 0.0 0.0036 17.0 0.1 6.0 5 0 0 5 5 5 4 Sigma-54 interaction domain TsaE PF02367.17 KFH49108.1 - 4.9e-18 65.3 3.5 0.0011 19.0 0.2 6.2 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFH49108.1 - 2e-17 63.7 0.1 0.0069 16.6 0.0 7.6 7 1 0 7 7 7 3 AAA domain AAA_18 PF13238.6 KFH49108.1 - 2e-16 60.7 3.7 0.03 14.9 0.0 7.5 7 0 0 7 7 6 3 AAA domain AAA_14 PF13173.6 KFH49108.1 - 9.9e-15 54.7 0.0 0.025 14.6 0.0 6.6 6 0 0 6 6 5 2 AAA domain RuvB_N PF05496.12 KFH49108.1 - 3.6e-14 52.8 3.1 0.0035 17.1 0.0 6.6 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KFH49108.1 - 5.5e-14 52.5 0.3 0.00026 21.1 0.0 5.5 5 0 0 5 5 5 2 Sigma-54 interaction domain NACHT PF05729.12 KFH49108.1 - 9.6e-14 51.6 2.6 0.13 12.2 0.1 6.1 5 0 0 5 5 5 4 NACHT domain RNA_helicase PF00910.22 KFH49108.1 - 1.5e-12 47.9 0.4 0.15 12.5 0.0 6.5 6 0 0 6 6 6 2 RNA helicase T2SSE PF00437.20 KFH49108.1 - 1.7e-12 47.0 1.4 0.016 14.3 0.0 6.2 7 0 0 7 7 6 3 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KFH49108.1 - 4.9e-11 42.8 2.0 0.029 14.3 0.1 6.0 6 0 0 6 6 6 2 RsgA GTPase AAA_25 PF13481.6 KFH49108.1 - 3.1e-10 40.0 1.3 0.54 9.8 0.0 5.7 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.6 KFH49108.1 - 3.6e-10 40.3 2.3 0.48 10.7 0.0 6.7 6 0 0 6 6 5 1 AAA domain Zeta_toxin PF06414.12 KFH49108.1 - 7.5e-10 38.4 5.6 0.12 11.7 0.0 6.5 6 0 0 6 6 5 2 Zeta toxin ABC_tran PF00005.27 KFH49108.1 - 1.8e-09 38.2 9.2 0.063 13.8 0.0 6.9 7 0 0 7 7 5 2 ABC transporter IstB_IS21 PF01695.17 KFH49108.1 - 2.6e-09 37.1 0.1 1.5 8.5 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_19 PF13245.6 KFH49108.1 - 8.5e-09 35.9 2.4 4.9 7.5 0.0 6.5 6 0 0 6 6 5 0 AAA domain NTPase_1 PF03266.15 KFH49108.1 - 1.1e-08 35.2 5.0 1.6 8.6 0.0 6.3 6 0 0 6 6 6 2 NTPase Mg_chelatase PF01078.21 KFH49108.1 - 1.7e-08 34.1 0.3 9.1 5.6 0.0 7.8 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KFH49108.1 - 4.7e-08 33.2 0.8 0.31 11.0 0.0 5.6 6 0 0 6 6 5 2 Rad17 P-loop domain DUF815 PF05673.13 KFH49108.1 - 1.4e-07 31.0 1.8 1 8.5 0.0 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFH49108.1 - 2.9e-07 30.3 1.8 0.1 12.3 0.0 4.9 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KFH49108.1 - 4.3e-07 29.7 2.8 1.1 8.8 0.0 5.4 6 0 0 6 6 4 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KFH49108.1 - 1.6e-06 27.7 2.7 7.5 6.4 0.0 6.7 8 0 0 8 8 6 0 P-loop containing region of AAA domain cobW PF02492.19 KFH49108.1 - 3.2e-06 26.8 2.8 8.5 5.9 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KFH49108.1 - 3.3e-06 27.2 0.0 5.2 6.9 0.0 6.0 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KFH49108.1 - 4.5e-06 26.7 0.1 1.8 8.6 0.0 5.2 5 0 0 5 5 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain TniB PF05621.11 KFH49108.1 - 5e-06 26.0 0.2 2.6 7.4 0.0 5.7 6 0 0 6 6 6 1 Bacterial TniB protein TIP49 PF06068.13 KFH49108.1 - 5.6e-06 25.8 1.7 3.3 6.8 0.0 5.0 6 0 0 6 6 5 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KFH49108.1 - 1.1e-05 25.3 0.1 1.1 9.0 0.0 5.2 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KFH49108.1 - 1.3e-05 25.0 2.8 7.9 6.1 0.8 7.0 7 1 0 7 7 6 0 AAA domain NB-ARC PF00931.22 KFH49108.1 - 1.4e-05 24.5 4.1 2.5 7.2 0.0 5.5 5 0 0 5 5 5 1 NB-ARC domain ResIII PF04851.15 KFH49108.1 - 1.6e-05 25.0 0.0 4 7.4 0.0 5.6 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit dNK PF01712.19 KFH49108.1 - 3.1e-05 23.9 2.0 13 5.6 0.0 5.3 5 0 0 5 5 5 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 KFH49108.1 - 3.5e-05 23.8 0.3 32 4.6 0.0 5.6 5 0 0 5 5 5 0 50S ribosome-binding GTPase DnaB_C PF03796.15 KFH49108.1 - 4.1e-05 23.0 0.3 0.03 13.7 0.0 3.8 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain Bac_DnaA PF00308.18 KFH49108.1 - 0.00011 22.1 0.8 12 5.6 0.0 5.7 7 0 0 7 7 5 0 Bacterial dnaA protein Roc PF08477.13 KFH49108.1 - 0.00016 21.9 1.1 8.7 6.6 0.0 5.4 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 KFH49108.1 - 0.00016 22.1 6.4 5.2 7.5 0.0 5.3 5 0 0 5 5 4 0 AAA domain ATP_bind_1 PF03029.17 KFH49108.1 - 0.00047 20.0 1.8 20 4.8 0.0 5.0 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein GAF_2 PF13185.6 KFH49108.1 - 0.00069 19.9 0.0 0.43 10.9 0.0 4.1 4 0 0 4 4 2 1 GAF domain Thymidylate_kin PF02223.17 KFH49108.1 - 0.00078 19.2 2.0 18 4.9 0.1 5.8 6 0 0 6 6 4 0 Thymidylate kinase MeaB PF03308.16 KFH49108.1 - 0.00085 18.4 1.0 0.34 9.9 0.1 3.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VWA PF00092.28 KFH49108.1 - 0.001 19.4 0.3 0.0085 16.4 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_9 PF12781.7 KFH49108.1 - 0.0018 17.5 0.0 0.61 9.2 0.0 4.6 6 0 0 6 6 4 1 ATP-binding dynein motor region CPT PF07931.12 KFH49108.1 - 0.0019 18.1 0.6 44 3.9 0.0 5.2 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KFH49108.1 - 0.0024 17.2 0.1 15 4.8 0.0 4.4 4 0 0 4 4 4 0 KaiC SRPRB PF09439.10 KFH49108.1 - 0.005 16.3 0.6 27 4.1 0.0 4.6 5 0 0 5 5 4 0 Signal recognition particle receptor beta subunit KTI12 PF08433.10 KFH49108.1 - 0.011 15.2 0.4 4.1 6.8 0.0 4.1 5 0 0 5 5 4 0 Chromatin associated protein KTI12 SKI PF01202.22 KFH49108.1 - 0.013 15.6 0.6 31 4.7 0.0 4.3 4 0 0 4 4 4 0 Shikimate kinase VWA_2 PF13519.6 KFH49108.1 - 0.014 16.0 0.9 0.044 14.4 0.1 2.4 2 0 0 2 2 1 0 von Willebrand factor type A domain KAP_NTPase PF07693.14 KFH49108.1 - 0.037 13.3 0.0 28 3.8 0.0 4.3 5 0 0 5 5 5 0 KAP family P-loop domain DEAD PF00270.29 KFH49108.1 - 0.057 13.2 0.3 19 5.0 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.16 KFH49108.1 - 0.073 12.5 1.1 9.5 5.6 0.0 4.1 5 0 0 5 5 4 0 PhoH-like protein AAA_8 PF12780.7 KFH49108.1 - 0.096 12.0 0.1 9.4 5.5 0.0 4.0 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 DUF87 PF01935.17 KFH49108.1 - 0.32 11.0 1.8 44 4.1 0.1 4.4 4 0 0 4 4 2 0 Helicase HerA, central domain MobB PF03205.14 KFH49108.1 - 0.67 9.9 5.2 47 3.9 0.1 5.1 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B VPS9 PF02204.18 KFH49109.1 - 4e-22 78.4 0.0 8.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFH49109.1 - 0.0035 17.6 0.2 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) Spt20 PF12090.8 KFH49109.1 - 0.15 11.7 18.5 0.15 11.6 9.9 2.3 2 0 0 2 2 2 0 Spt20 family ASD2 PF08687.11 KFH49109.1 - 0.17 11.4 9.4 1.6 8.2 0.7 3.1 3 0 0 3 3 3 0 Apx/Shroom domain ASD2 Roughex PF06020.11 KFH49109.1 - 0.94 8.5 11.8 0.11 11.6 4.4 2.5 2 0 0 2 2 2 0 Drosophila roughex protein SPG4 PF17325.2 KFH49109.1 - 4.2 8.5 9.3 2 9.5 2.0 2.8 2 0 0 2 2 2 0 Stationary phase protein 4 RR_TM4-6 PF06459.12 KFH49109.1 - 4.9 6.9 7.2 2.2 8.0 0.3 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SUIM_assoc PF16619.5 KFH49109.1 - 7.8 6.7 25.7 0.22 11.6 8.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Band_3_cyto PF07565.13 KFH49109.1 - 9.3 6.0 10.0 4.2 7.1 2.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acremonium_chrysogenum_ATCC_11550-ASM76926v1/GCA_000769265.1_ASM76926v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acremonium_chrysogenum_ATCC_11550-ASM76926v1/GCA_000769265.1_ASM76926v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acremonium_chrysogenum_ATCC_11550-ASM76926v1/GCA_000769265.1_ASM76926v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acremonium_chrysogenum_ATCC_11550-ASM76926v1/GCA_000769265.1_ASM76926v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 11:05:16 2019 # [ok]